ssp6004
- Apparent physicochemical properties on 2-D gel
- Molecular mass = 17.75 kDa
- Isoelectric point = 5.89
- Identification
Protein name = Nucleoside diphosphate kinase A (nm23-H1)
- Theoretical properties
- Molecular mass (Isoform 1) = 17,149 Da
- Isoelectric point (Isoform 1) = 5.81
- Tissue/cell specificity
Isoform 1 is expressed in heart, brain, placenta, lung, liver, skeletal muscle, pancreas, spleen and thymus. Expressed in lung carcinoma cell lines but not in normal lung tissues. Isoform 2 is ubiquitously expressed and its expression is also related to tumor differentiation.
- Intracellular localization
Nucleus, cytoplasm
- Activities/functions
Major role in the synthesis of nucleoside triphosphates other than ATP.
- Related databases
UniProtKB/Swiss-Prot: P15531 (NDKA_HUMAN)