ssp2419
- Apparent physicochemical properties on 2-DE gel
- Molecular mass = 55.39 kDa
- Isoelectric point = 5.40
- Identification
Protein name = 60 kDa heat shock protein, mitochondrial (Hsp60)
- Method: Matching to the corresponding pot on MRC-5 2-DE database (J. E. Celis)
- Theoretical properties
- Molecular mass = 57,963 Da (Processed form)
- Isoelectric point = 5.24 (Processed form)
- Tissue/cell specificity
Ubiquitous
- Intracellular localization
Mitochondrial
- Activities/functions
Chaperonin implicated in mitochondrial protein import and macromolecular assembly. Together with Hsp10, facilitates the correct folding of imported proteins. May also prevent misfolding and promote the refolding and proper assembly of unfolded polypeptides generated under stress conditions in the mitochondrial matrix.
- Related databases
UniProtKB/Swiss-Prot: P10809 (CH60_HUMAN)