ssp16
- Identification
Protein name = 14-3-3 protein zeta/delta (Protein kinase C inhibitor protein 1)
- Method of identification: PMF
- Apparent physicochemical properties on 2-DE gel
- Molecular mass = 26.76 kDa
- Isoelectric point = 5.05
- Theoretical Mw and pI
- Tissue/cell specificity
14-3-3 Proteins are highly expressed in neurons, and axonally transported to the nerve ternimals. They may be also present, at lower levels, in various other tissues.
The delta, brain-specific form differs from the zeta form in being phosphorylated.
- Intracellular localization
Cytoplasm
- Activities/functions
Binds to a large number of phosphoproteins by recognition of a phosphoserine or phosphothreonine motif. Binding results in the modulation of the activity of the binding partner.
(It was originally thought to have phospholipase A2 activity.)
- Related databases
SWISS-PROT AC: P63104 (1433Z_HUMAN)