ssp3323
- Apparent physicochemical properties on 2-DE gel
- Molecular mass = 46.14 kDa
- Isoelectric point = 5.55
- Identification
Protein name = Vimentin
- Method: peptide mass fingerprint (PMF)
- Theoretical properties
- Molecular mass = 53,554 Da
- Isoelectric point = 5.1
- Tissue/cell specificity
Highly expressed in fibroblasts, some expression in T and B lymphocytes, and little or no expression in Burkitt's lymphoma cell lines. Expressed in many hormone-independent mammary carcinoma cell lines.
- Intracellular localization
Cytoplasmic
- Post-translational modification
Phosphorylation is enhanced during cell division, at which time vimentin filaments are significantly reorganized.
- Activities/functions
A componet of class-III intermediate filaments found in various non-epithelial cells, especially mesenchymal cells.
- Related databases
UniProtKB/Swiss-Prot: P08670 (VIME_HUMAN)