TMIG-2DPAGE Proteome Database of TIG-3 for Cellular Aging Research
TIG-3: normal human diploid fibroblast
cell strain
The cell strain TIG-3, which was established in our institute,
shows
the finite life span up to 70-80 population doubling levels (PDLs). The
cell strain has been widely used for researches on molecular mechanisms
of replicative cell aging and
immortalization. The preparation of our 2-D gel-based proteome database
was
intended for promoting proteomic researches on cellular aging. (Toda T,
Kaji K,
Kimura N. Electrophoresis 19(2), 344-348, 1998) (Toda
T, Satoh M, Sugimoto M, Goto M, Furuichi Y, Kimura N. Mech Ageing Dev 100(2):133-143, 1998) (Toda
T. Experimental
Gerontology 35: 803-810, 2000 (PDF))
( Toda T. Ann N Y Acad Sci 928:71-78, 2001)
The clickable 2-D gel image map:
The colored symbols indicate alterations in each protein spot
with cellular aging.
