Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI >sp|TRYP_PIG| 32.90 1 6 6 631 1.732E10 943.18 32.90 6 315 42601.11 25.11 5 316 231 24.4 7.18 HVO_0239 glutamine synthetase 73.90 1 30 33 1782 8.880E9 2339.26 68.42 31 883 121435.95 69.52 30 899 456 50.5 4.56 HVO_2757 50S ribosomal protein L1 88.68 1 21 21 1932 7.665E9 2703.61 83.96 20 954 118755.29 88.68 21 978 212 23.1 4.42 HVO_2564 50S ribosomal protein L3 76.63 1 21 21 1646 7.654E9 1649.11 73.96 19 835 79347.02 76.63 21 811 338 37.2 6.68 HVO_0455 thermosome subunit 2 75.04 1 39 41 3561 7.484E9 5055.67 75.04 41 1810 244814.43 75.04 41 1751 557 59.3 4.37 HVO_0133 thermosome subunit 1 74.11 1 33 35 4213 7.459E9 5223.30 74.11 35 2067 253077.61 74.11 35 2146 560 58.9 4.25 HVO_0778 thermosome subunit 3 72.14 1 33 35 2152 6.683E9 3352.64 71.18 34 1072 160646.72 72.14 35 1080 524 55.2 4.59 HVO_2547 50S ribosomal protein L32e 52.77 1 9 10 617 6.428E9 742.84 45.53 9 301 35026.15 52.77 10 316 235 25.8 4.75 HVO_2561 50S ribosomal protein L2 39.83 1 12 12 761 6.398E9 769.08 39.83 12 373 44630.71 39.83 12 388 241 25.6 10.40 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 62.33 1 14 14 1429 5.676E9 1728.46 62.33 14 728 66351.65 57.03 13 701 377 39.2 4.18 HVO_1145 30S ribosomal protein S1e 83.18 1 23 23 1126 5.640E9 1410.02 82.73 21 560 60187.99 83.18 22 566 220 24.8 4.86 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 38.24 1 15 15 984 5.483E9 928.87 37.91 14 489 51951.78 38.24 15 495 612 67.3 4.16 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 60.06 1 24 25 784 3.841E9 861.11 60.06 24 390 42329.09 56.89 24 394 631 68.4 4.49 HVO_2072 S-layer glycoprotein 16.32 1 6 6 2991 3.792E9 3634.25 16.32 6 1489 140594.59 16.32 6 1502 827 85.1 3.65 HVO_0980 NADH dehydrogenase-like complex subunit CD 71.81 1 22 29 618 3.657E9 590.22 61.58 27 309 34748.75 70.74 28 309 557 63.4 4.53 HVO_0317 A-type ATP synthase subunit B 66.88 1 25 25 397 3.505E9 481.78 61.54 24 195 24309.95 66.88 25 202 468 51.9 4.25 HVO_0561 50S ribosomal protein L15e 26.53 1 6 7 81 3.471E9 71.81 26.53 7 40 4481.87 26.53 7 41 196 22.5 11.15 HVO_2548 50S ribosomal protein L6 95.51 1 13 13 878 3.206E9 1153.84 89.33 11 426 53444.16 95.51 13 452 178 19.6 4.68 HVO_0812 phosphoenolpyruvate synthase 57.03 1 39 39 742 2.979E9 729.27 55.85 37 369 37690.84 55.19 37 373 761 83.1 4.63 HVO_0359 translation elongation factor aEF-1 alpha subunit 79.57 1 16 19 565 2.942E9 671.24 66.51 17 274 35797.90 79.57 19 291 421 45.7 4.73 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 56.78 1 16 16 489 2.874E9 520.76 56.78 16 240 24461.14 56.78 16 249 398 43.4 4.37 HVO_1091 proteasome alpha subunit 66.27 1 13 15 290 2.871E9 327.31 65.87 14 147 16876.18 64.29 14 143 252 27.6 4.56 HVO_1578 probable NADH dehydrogenase 48.61 1 21 21 854 2.852E9 1268.27 48.61 21 424 59954.22 48.61 21 430 397 42.8 4.40 HVO_2756 50S ribosomal protein L10 64.66 1 13 13 756 2.841E9 1035.14 64.66 13 377 39256.18 64.66 13 379 348 36.9 3.99 HVO_1488 D-gluconate dehydratase 48.54 1 13 17 492 2.752E9 591.18 47.57 15 244 27905.59 48.54 17 248 412 45.8 4.60 HVO_0484 50S ribosomal protein L10e 48.86 1 10 10 274 2.729E9 246.29 48.86 10 134 15592.84 46.59 9 140 176 19.8 8.72 HVO_A0133 conserved hypothetical protein 48.97 1 14 14 443 2.426E9 656.98 48.97 14 220 30942.02 48.97 14 223 292 30.8 5.17 HVO_2153 probable copper-containing oxidoreductase 60.78 1 19 19 472 2.226E9 447.02 60.78 19 239 25426.50 60.78 19 233 385 42.1 5.82 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 58.33 1 11 11 478 2.095E9 436.69 58.33 11 249 22571.30 58.33 11 229 312 34.5 4.98 HVO_2542 50S ribosomal protein L15 59.39 1 9 9 251 2.072E9 364.85 59.39 9 126 16283.90 59.39 9 125 165 17.8 4.93 HVO_2543 50S ribosomal protein L30 56.49 1 7 7 217 1.990E9 223.22 56.49 7 107 13974.96 56.49 7 110 154 17.1 4.77 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 29.29 1 5 5 479 1.890E9 673.78 29.29 5 242 33142.32 29.29 5 237 297 32.3 3.98 HVO_0968 NADH dehydrogenase-like complex subunit CD 10.64 1 0 7 119 1.855E9 116.81 10.64 7 59 7797.46 9.57 6 60 564 63.3 4.60 HVO_2724 beta-lactamase domain protein 68.89 1 26 26 651 1.770E9 581.89 68.89 26 313 33920.18 67.78 25 338 450 50.1 5.40 HVO_2774 enolase 50.88 1 14 14 280 1.760E9 271.06 48.62 12 146 15213.88 50.88 14 134 399 42.0 4.37 HVO_1020 HEAT-PBS family protein 44.87 1 17 17 448 1.725E9 486.52 39.14 15 220 28008.69 44.87 17 228 419 45.5 3.95 HVO_0801 stomatin family protein 57.08 1 23 27 458 1.702E9 604.74 57.08 27 229 30808.46 57.08 27 229 424 46.4 4.37 HVO_0316 A-type ATP synthase subunit A 47.27 1 19 19 345 1.666E9 481.36 45.73 18 173 23216.48 37.54 17 172 586 64.5 4.25 HVO_2563 50S ribosomal protein L4 75.00 1 16 16 392 1.614E9 400.18 75.00 16 194 19777.75 75.00 16 198 248 27.0 6.44 HVO_2545 50S ribosomal protein L18 72.83 1 5 5 487 1.545E9 593.44 72.83 5 242 28618.34 72.83 5 245 184 20.2 5.60 HVO_2554 50S ribosomal protein L14 53.79 1 9 9 543 1.498E9 707.46 50.00 8 273 28982.03 43.94 8 270 132 14.2 9.76 HVO_2784 30S ribosomal protein S13 67.07 1 11 11 89 1.478E9 84.48 56.89 10 44 5315.97 67.07 11 45 167 18.9 5.17 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 57.72 1 26 26 619 1.462E9 662.89 57.72 26 311 34337.14 57.72 26 308 615 67.6 4.88 HVO_2380 AAA-type ATPase (CDC48 subfamily) 73.76 1 47 47 614 1.297E9 667.95 71.74 45 307 36317.40 73.76 47 307 743 81.9 4.82 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 68.86 1 15 15 314 1.261E9 328.06 68.86 15 155 16938.54 68.86 15 159 350 37.6 4.54 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 42.00 1 11 11 179 1.258E9 171.93 42.00 11 88 8159.02 42.00 11 91 400 44.2 4.32 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 46.95 1 27 27 444 1.238E9 558.66 46.95 27 222 27192.05 46.95 27 222 573 62.9 4.45 HVO_1508 acetolactate synthase large subunit 43.61 1 14 15 451 1.205E9 596.76 42.25 14 226 26370.12 43.61 15 225 587 62.3 4.36 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 44.59 1 10 10 360 1.192E9 349.61 44.59 10 173 17287.80 44.59 10 187 388 41.9 4.35 HVO_0356 translation elongation factor aEF-2 58.73 1 33 33 409 1.189E9 470.57 58.73 33 207 22233.40 58.73 33 202 727 80.4 4.73 HVO_2779 50S ribosomal protein L18e 85.34 1 10 10 144 1.171E9 207.42 85.34 10 73 9490.03 85.34 10 71 116 12.7 8.50 HVO_1506 ketol-acid reductoisomerase 63.79 1 15 15 597 1.163E9 554.27 59.48 13 277 28491.22 63.79 15 320 348 37.9 4.34 HVO_2620 cytochrome bc1 complex Rieske iron-sulfur protein 53.38 1 6 6 148 1.157E9 188.03 53.38 6 75 8870.34 53.38 6 73 281 30.2 4.31 HVO_0725 probable oxidoreductase (short-chain dehydrogenase family) 71.89 1 15 16 243 1.123E9 320.95 71.89 16 122 16098.99 71.89 15 121 281 30.2 4.78 HVO_1540 glycerol-3-phosphate dehydrogenase subunit C 33.26 1 12 12 166 1.075E9 208.07 33.26 12 84 11688.79 26.15 11 82 436 48.6 4.61 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 43.00 1 19 19 363 1.034E9 443.20 39.42 18 183 23461.70 43.00 19 180 586 64.0 4.49 HVO_0841 cytochrome bc1 complex cytochrome b/c subunit 34.25 1 7 7 116 9.893E8 145.38 29.92 6 58 7588.19 34.25 7 58 254 28.8 5.72 HVO_2889 RecJ domain protein 55.83 1 31 31 511 9.780E8 652.31 55.83 31 257 34354.27 55.83 31 254 729 79.1 4.37 HVO_2160 conserved hypothetical protein 17.01 1 23 23 374 9.663E8 503.66 17.01 23 189 23899.40 17.01 23 185 2257 232.7 3.92 HVO_0979 NADH dehydrogenase-like complex subunit B 40.77 1 11 11 142 9.466E8 146.29 40.77 11 69 8690.79 40.77 11 73 233 26.1 5.01 HVO_0783 ATP-dependent protease La 54.61 1 25 25 303 9.389E8 282.31 54.61 24 151 15706.49 54.61 25 152 694 75.4 4.86 HVO_0311 A-type ATP synthase subunit I 33.70 1 18 18 263 9.073E8 246.24 33.70 18 129 14014.67 33.70 18 134 733 79.5 4.41 HVO_1888 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfate/tungstate) 34.21 1 8 9 151 8.874E8 214.72 33.04 8 76 9368.09 34.21 9 75 342 35.9 4.34 HVO_2070 conserved hypothetical protein 35.48 1 13 13 280 8.618E8 371.15 35.48 13 139 17722.60 35.48 13 141 544 58.1 4.50 HVO_1831 ferredoxin (2Fe-2S) 41.45 1 5 5 102 8.567E8 127.67 22.80 4 49 6411.70 41.45 5 53 193 20.4 3.98 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 43.03 1 10 10 1849 8.309E8 2647.18 43.03 10 927 93505.48 43.03 10 922 574 62.8 4.17 HVO_0349 DNA-directed RNA polymerase subunit A' 53.48 1 42 42 727 8.257E8 926.74 53.48 42 367 47128.52 50.82 40 360 976 108.8 4.81 HVO_1603 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfonate) 37.64 1 6 6 165 7.911E8 230.88 37.64 6 82 8283.93 37.64 6 83 348 37.2 4.35 HVO_1871 UPF0447 family protein 32.73 1 13 13 234 7.874E8 238.33 29.34 12 113 14131.52 32.73 13 121 501 56.1 4.59 HVO_2900 fumarate hydratase 66.31 1 19 19 291 7.625E8 361.11 66.31 19 145 16171.05 66.31 19 146 469 50.1 4.78 HVO_1692 probable iron-sulfur protein (4Fe-4S) 45.98 1 22 23 222 7.552E8 231.58 45.98 23 111 13031.45 36.70 21 111 733 80.2 4.49 HVO_1228 halocyanin 28.14 1 15 15 334 7.412E8 456.43 27.53 14 170 21478.74 28.14 15 164 821 83.7 4.17 HVO_2080 conserved hypothetical protein 28.89 1 7 7 141 7.200E8 155.31 28.89 7 71 6953.34 28.89 7 70 540 57.0 4.30 HVO_2553 50S ribosomal protein L24 38.98 1 4 4 68 7.142E8 58.92 38.98 4 34 3853.17 38.98 4 34 118 13.4 4.73 HVO_2552 30S ribosomal protein S4e 35.63 1 7 7 66 7.081E8 83.41 35.63 7 33 4222.98 35.63 7 33 247 26.6 4.58 HVO_0329 branched-chain amino acid aminotransferase 75.64 1 20 20 288 7.028E8 355.61 75.64 20 144 18663.34 75.64 20 144 312 35.0 4.58 HVO_3007 malate dehydrogenase 44.08 1 11 11 126 6.992E8 140.49 44.08 11 62 6486.52 44.08 11 64 304 32.6 4.40 HVO_1530 dolichyl-monophosphooligosaccharide--protein glycotransferase AglB 26.85 1 19 19 237 6.961E8 268.30 26.85 19 118 13904.17 26.85 19 119 1054 113.6 4.56 HVO_0447 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate/phosphonate) 20.40 1 2 2 134 6.720E8 81.72 20.40 2 66 3209.49 20.40 2 68 348 36.5 3.75 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 30.72 1 13 13 180 6.685E8 234.93 30.72 13 90 11406.00 30.72 13 90 586 63.4 4.70 HVO_2758 50S ribosomal protein L11 40.25 1 6 6 66 6.682E8 76.74 32.70 5 31 3619.39 40.25 6 35 159 16.8 4.04 HVO_2621 phosphoenolpyruvate carboxylase 54.52 1 41 42 549 6.545E8 689.16 54.52 42 275 31964.81 54.52 42 274 897 102.3 4.64 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 15.65 1 3 3 66 6.484E8 45.17 15.65 3 33 2407.86 15.65 3 33 345 37.0 3.95 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 39.75 1 0 24 219 6.481E8 275.49 38.82 23 110 14196.92 37.58 23 109 644 66.0 8.12 17318569 keratin 1 [Homo sapiens] 41.15 1 1 25 223 6.481E8 280.00 40.22 24 112 14460.53 38.98 24 111 644 66.0 8.12 HVO_1976 protein-export membrane protein SecD 41.79 1 12 13 125 6.357E8 216.71 41.79 13 64 10883.32 41.79 13 61 524 55.0 4.51 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 53.81 1 13 13 184 6.355E8 250.26 53.81 13 92 12428.63 53.81 13 92 381 41.0 4.23 HVO_0907 cox-type terminal oxidase subunit I 16.19 1 6 6 64 6.329E8 64.41 15.19 5 32 3343.25 16.19 6 32 599 65.7 5.11 HVO_0869 glutamate synthase large subunit 57.84 1 67 68 732 6.199E8 889.99 57.84 68 368 47104.92 57.84 68 364 1511 163.8 4.70 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 59.93 1 10 10 167 6.047E8 180.35 59.93 10 84 9889.32 59.93 10 83 287 31.0 4.73 HVO_2798 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 13.73 1 4 4 74 6.043E8 63.23 13.73 4 36 3496.26 13.73 4 38 437 44.6 3.95 HVO_0117 translation initiation factor aIF-6 33.48 1 6 6 89 5.864E8 120.56 33.48 6 44 5514.48 33.48 6 45 221 23.0 4.27 HVO_1014 cox-type terminal oxidase subunit II 14.68 1 2 2 96 5.811E8 99.78 14.68 2 50 4444.51 14.68 2 46 252 27.7 4.59 7428712 "keratin 1, type II, cytoskeletal - human" 28.93 1 0 18 189 5.711E8 238.35 28.93 18 95 11932.50 28.93 18 94 643 65.5 6.35 HVO_2923 proteasome alpha subunit 52.61 1 9 11 76 5.708E8 78.23 52.61 11 39 4338.85 50.60 10 37 249 26.7 4.39 HVO_2544 30S ribosomal protein S5 28.50 1 5 5 42 5.666E8 57.70 23.83 4 22 2835.41 23.83 4 20 214 23.3 9.29 HVO_1273 inosine-5'-monophosphate dehydrogenase 61.04 1 20 20 345 5.483E8 377.13 58.43 19 173 18326.54 61.04 20 172 498 53.3 4.55 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 53.01 1 11 11 117 5.364E8 144.28 53.01 11 58 7668.19 53.01 11 59 266 27.8 4.84 HVO_B0038A D-xylonate dehydratase 19.66 1 2 7 46 5.349E8 30.89 14.32 6 23 2053.01 19.66 7 23 412 45.5 4.55 HVO_2759 peptidase M42 family protein 72.32 1 19 19 242 5.321E8 311.01 72.32 19 121 15303.27 72.32 19 121 354 37.0 4.40 HVO_0987 NADH dehydrogenase-like complex subunit M 13.36 1 5 5 51 5.291E8 47.05 13.36 5 26 2973.34 13.36 5 25 509 54.7 5.08 HVO_1975 protein-export membrane protein SecF 15.33 1 3 3 52 5.278E8 69.30 11.15 2 24 3924.96 15.33 3 28 287 30.4 4.55 HVO_2541 protein translocase subunit SecY 17.79 1 6 8 118 5.176E8 90.06 17.79 8 59 5815.19 16.97 7 59 489 52.3 6.81 HVO_1778 catalase-peroxidase 39.00 1 20 20 175 5.176E8 164.94 38.72 19 88 8782.06 39.00 20 87 718 80.0 4.31 HVO_A0207 CRISPR-associated protein Cas7 59.71 1 12 12 168 5.114E8 183.82 59.71 12 84 8816.76 59.71 12 84 340 38.2 4.54 HVO_1562 proteasome beta subunit 41.98 1 8 8 235 4.964E8 239.16 41.98 8 122 12536.66 41.98 8 113 243 26.0 4.63 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 65.88 1 19 20 159 4.935E8 193.45 61.18 17 75 10076.79 65.88 20 84 340 38.8 4.58 HVO_2809 succinate dehydrogenase subunit B (iron-sulfur protein) 33.79 1 13 13 125 4.901E8 96.59 33.79 13 62 6305.00 33.79 13 63 293 33.9 5.27 HVO_1400 ABC-type transport system ATP-binding protein (probable substrate sugar) 73.03 1 28 28 246 4.815E8 255.79 70.91 27 123 12836.22 71.68 27 123 519 56.8 4.68 HVO_1522 hexuronic acid methyltransferase AglP 60.25 1 14 14 116 4.805E8 112.28 56.07 13 56 6438.59 60.25 14 60 239 26.2 4.98 HVO_0832 alpha/beta hydrolase fold protein 26.30 1 6 6 157 4.630E8 186.49 26.30 6 77 11379.72 26.30 6 80 308 33.3 4.67 HVO_0049 argininosuccinate synthase 31.36 1 11 11 174 4.581E8 145.07 31.36 11 87 8528.93 31.36 11 87 405 44.5 4.34 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 58.76 1 26 26 303 4.573E8 360.31 58.76 26 151 18392.53 58.76 26 152 599 65.3 4.51 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 51.49 1 17 17 138 4.536E8 142.90 51.49 17 69 8238.47 51.49 17 69 336 38.0 4.61 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 66.82 1 16 17 191 4.530E8 228.70 66.82 17 96 11828.38 65.88 16 95 422 43.6 4.72 HVO_0972 DUF1628 family protein 53.18 1 4 4 480 4.480E8 855.82 53.18 4 241 37731.98 53.18 4 239 173 17.7 4.09 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 33.85 1 24 25 210 4.465E8 218.62 33.41 24 105 11404.37 33.85 25 105 898 97.7 4.45 HVO_2015 conserved hypothetical protein 34.20 1 8 8 126 4.341E8 149.21 34.20 8 64 7461.32 34.20 8 62 345 37.7 4.25 HVO_2551 50S ribosomal protein L5 27.91 1 5 5 137 4.282E8 160.73 27.91 5 69 8698.21 27.91 5 68 172 19.1 4.78 HVO_0314 A-type ATP synthase subunit C 50.29 1 16 16 162 4.263E8 201.17 46.26 15 79 11053.25 45.69 15 83 348 38.7 4.50 HVO_2436 malic enzyme (NADP) 47.14 1 19 24 352 4.259E8 458.85 47.14 24 177 22091.12 47.14 24 175 751 81.4 4.55 HVO_2778 50S ribosomal protein L13 53.79 1 6 6 94 4.220E8 125.62 53.79 6 48 6356.20 49.66 5 46 145 16.0 5.43 HVO_0677 aspartate--tRNA ligase 58.53 1 16 16 215 4.199E8 238.19 58.53 16 107 11604.09 58.53 16 108 434 48.7 4.50 47132620 keratin 2a [Homo sapiens] 28.64 1 8 14 87 4.147E8 92.92 28.64 14 44 5435.21 28.64 14 43 639 65.4 8.00 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 38.75 1 7 7 115 4.098E8 168.78 38.75 7 58 7929.26 36.68 6 57 289 29.8 4.27 HVO_2378 ABC-type transport system ATP-binding protein (probable substrate phosphate) 36.82 1 14 14 107 4.015E8 112.44 36.82 14 52 6612.20 36.82 14 55 296 32.6 4.44 HVO_0817 phytoene dehydrogenase (phytoene desaturase) 64.00 1 24 24 278 3.975E8 326.08 64.00 24 140 15910.23 64.00 24 138 425 46.1 4.98 HVO_1018 RecJ domain protein 48.03 1 26 27 248 3.957E8 259.82 48.03 27 123 15166.11 48.03 27 125 633 69.8 4.58 HVO_1590 DnaK-type molecular chaperone Hsp70 38.08 1 17 17 120 3.923E8 146.38 38.08 17 60 7031.85 33.12 16 60 625 67.2 4.18 HVO_1613 "probable glycosyltransferase, type 2" 25.44 1 4 4 31 3.915E8 35.93 25.44 4 15 2062.78 25.44 4 16 228 25.1 4.79 HVO_2636 PspA domain protein 61.23 1 14 15 120 3.891E8 148.52 57.97 13 58 7202.77 61.23 15 62 276 30.9 4.61 HVO_2588 isocitrate dehydrogenase (NADP) 55.61 1 20 20 179 3.888E8 188.53 52.51 19 89 9195.85 55.61 20 90 419 45.8 4.59 HVO_1955 aconitate hydratase 35.78 1 16 16 171 3.878E8 218.21 35.78 16 85 10900.46 35.78 16 86 654 70.4 4.45 31074631 keratin 1b [Homo sapiens] 3.29 1 0 2 16 3.781E8 18.39 3.29 2 8 1036.53 3.29 2 8 578 61.8 5.97 HVO_2336 pyridoxal biosynthesis lyase PdxS 68.54 1 13 13 174 3.778E8 239.09 64.90 11 83 12639.29 66.23 12 91 302 32.5 4.81 HVO_1799 geranylgeranyl reductase / dolichol omega-reductase 58.78 1 15 15 227 3.677E8 266.20 53.90 14 110 14978.47 58.78 15 117 410 45.4 4.75 HVO_0981 NADH dehydrogenase-like complex subunit H 12.03 1 5 5 26 3.663E8 31.66 12.03 5 13 1821.81 12.03 5 13 349 36.9 5.19 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 53.88 1 24 24 281 3.633E8 359.51 51.94 23 139 18016.31 53.88 24 142 516 56.7 4.89 HVO_0986 NADH dehydrogenase-like complex subunit L 9.59 1 6 7 67 3.611E8 62.71 9.59 7 34 3473.85 9.00 6 33 678 71.7 6.14 HVO_2862 serine hydroxymethyltransferase 59.28 1 12 12 139 3.572E8 167.05 59.28 12 69 8544.11 59.28 12 70 415 44.3 4.53 HVO_0035 stomatin family protein 46.63 1 9 13 110 3.536E8 139.15 46.38 12 53 7288.65 46.63 13 57 401 43.6 4.65 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 34.25 1 9 9 83 3.482E8 86.22 34.25 9 41 4807.10 34.25 9 42 435 46.9 4.63 HVO_2495 DUF106 family protein 36.72 1 10 10 216 3.432E8 258.31 36.72 10 111 13994.66 36.72 10 105 305 33.5 4.58 HVO_2324 SSSF family transport protein 10.42 1 5 5 43 3.317E8 49.74 10.42 5 21 2351.12 10.42 5 22 499 52.9 6.60 HVO_0806 pyruvate kinase 38.63 1 15 15 153 3.311E8 169.87 38.63 15 75 8367.25 36.75 14 78 585 62.0 4.54 HVO_1605 probable NhaC-type sodium/proton antiporter 18.85 1 6 6 22 3.261E8 33.24 18.85 6 12 1339.11 7.88 4 10 520 54.9 4.86 HVO_0530 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 17.94 1 4 4 115 3.219E8 134.39 17.94 4 61 5525.49 17.94 4 54 457 48.1 4.11 HVO_1541 glycerol kinase 47.06 1 15 15 92 3.216E8 87.45 43.73 14 45 5504.67 47.06 15 47 510 56.7 4.50 HVO_1684 threonine--tRNA ligase 42.92 1 25 25 194 3.198E8 200.85 42.92 25 99 10627.96 41.99 24 95 643 73.4 4.45 HVO_2538 alpha/beta hydrolase fold protein 49.20 1 11 11 117 3.187E8 136.28 49.20 11 57 8010.93 49.20 11 60 313 33.8 6.06 HVO_2555 30S ribosomal protein S17 65.79 1 5 5 91 3.145E8 87.15 46.49 4 39 5824.80 65.79 5 52 114 12.7 4.81 HVO_2204 "FtsZ family protein, type III" 42.53 1 11 13 126 3.140E8 148.42 42.53 13 63 7542.49 42.53 13 63 395 42.0 4.68 HVO_2049 "probable glycosyltransferase, type 2" 32.57 1 9 9 51 3.137E8 54.58 32.57 9 25 2738.65 32.57 9 26 307 35.3 5.40 HVO_2487 aspartate-semialdehyde dehydrogenase 54.65 1 10 10 132 3.123E8 121.74 54.65 10 68 5443.49 54.65 10 64 344 36.6 4.41 HVO_2947 phenylalanine--tRNA ligase beta subunit 44.21 1 16 16 145 3.092E8 107.46 42.11 14 68 7260.79 44.21 16 77 570 63.3 4.46 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 44.01 1 11 11 118 3.077E8 145.65 44.01 11 59 7469.76 44.01 11 59 359 39.4 4.91 HVO_1348 probable YjeF family carbohydrate kinase 50.00 1 17 17 135 3.026E8 178.37 49.16 16 67 8891.64 50.00 17 68 478 48.8 4.45 HVO_0945 ba3-type terminal oxidase subunit I 5.26 1 4 4 30 2.974E8 23.77 5.26 4 15 1634.55 5.26 4 15 589 64.3 6.71 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 57.05 1 25 25 210 2.945E8 241.25 57.05 25 106 11251.65 57.05 25 104 624 67.6 4.27 HVO_0773 probable S-adenosylmethionine-dependent methyltransferase 61.35 1 15 15 116 2.897E8 117.13 56.57 13 57 7172.25 61.35 15 59 251 27.8 6.06 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 45.22 1 17 17 123 2.894E8 118.85 45.22 16 60 5834.57 45.22 17 63 471 51.0 4.48 HVO_2560 30S ribosomal protein S19 63.57 1 7 8 68 2.879E8 57.93 60.71 7 33 3602.71 63.57 8 35 140 16.0 5.57 HVO_2158 malic enzyme (NADP) 32.09 1 8 13 145 2.867E8 166.32 32.09 13 73 8059.76 32.09 13 72 751 81.4 4.55 HVO_1189 aldehyde dehydrogenase 55.31 1 22 22 191 2.809E8 176.33 48.03 21 94 9606.89 49.61 21 97 508 56.1 4.59 HVO_2948 phenylalanine--tRNA ligase alpha subunit 47.70 1 11 11 203 2.797E8 293.07 47.70 11 101 12881.65 47.70 11 102 499 55.1 4.41 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 19.61 1 7 7 46 2.793E8 38.79 19.61 7 24 2104.60 19.61 7 22 357 40.3 4.40 HVO_0250 DUF21/CBS domain protein 25.27 1 9 9 85 2.750E8 106.58 25.27 9 43 5266.01 25.27 9 42 471 51.7 4.28 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 109 2.741E8 153.95 38.05 9 55 7147.64 36.66 8 54 431 46.1 4.48 HVO_2960 dihydrolipoamide S-acyltransferase 33.59 1 15 15 117 2.715E8 143.95 33.59 15 58 6667.15 33.59 15 59 521 54.9 4.40 HVO_0763 YphA family protein 22.86 1 1 4 74 2.639E8 43.97 16.00 3 29 5449.94 22.86 4 45 175 18.9 6.54 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 39.33 1 17 18 187 2.631E8 162.38 39.33 18 88 10166.66 39.33 18 99 623 62.1 5.30 HVO_2690 GFO family oxidoreductase 37.16 1 10 10 77 2.584E8 70.72 37.16 10 39 4174.68 37.16 10 38 366 40.0 4.60 HVO_1542 conserved hypothetical protein 22.88 1 4 4 68 2.580E8 86.93 22.88 4 34 4639.60 22.88 4 34 354 36.1 5.48 HVO_2046 sulfatase domain protein 55.06 1 16 16 155 2.554E8 158.89 55.06 16 80 8002.98 53.83 15 75 405 45.5 4.87 HVO_1084 adenylosuccinate lyase 46.87 1 16 18 95 2.552E8 103.95 46.87 18 50 5153.57 44.49 16 45 463 50.8 4.70 HVO_2777 30S ribosomal protein S9 53.79 1 7 7 63 2.540E8 61.17 53.79 7 31 3916.60 53.79 7 32 132 14.7 9.74 HVO_A0548 YphA family protein 22.86 1 1 4 64 2.501E8 43.97 16.00 3 29 3938.50 22.86 4 35 175 18.9 6.54 HVO_0729 inorganic pyrophosphatase 34.46 1 7 7 83 2.482E8 89.78 34.46 7 41 4748.34 34.46 7 42 177 20.4 4.16 HVO_1673 conserved hypothetical protein 42.59 1 7 7 48 2.452E8 66.79 42.59 7 24 3353.40 42.59 7 24 216 23.2 4.58 HVO_0861 SufB domain protein 45.02 1 13 13 145 2.443E8 199.10 45.02 13 72 9463.66 45.02 13 73 402 44.7 4.23 HVO_1507 acetolactate synthase small subunit 73.85 1 16 16 138 2.419E8 176.17 73.85 16 69 8282.84 66.06 15 69 218 23.7 4.94 HVO_2782 30S ribosomal protein S11 43.85 1 5 5 112 2.405E8 126.27 43.85 5 58 7068.19 43.85 5 54 130 13.4 8.56 HVO_0313 A-type ATP synthase subunit E 54.64 1 6 6 75 2.376E8 91.05 47.42 4 32 5263.07 54.64 6 43 194 22.0 4.31 HVO_1529 glycosyltransferase AglG 27.16 1 9 9 94 2.359E8 88.01 27.16 9 46 4772.13 27.16 9 48 313 35.8 4.59 HVO_1858 30S ribosomal protein S19e 85.43 1 12 13 65 2.350E8 42.08 70.86 11 28 3875.09 85.43 13 37 151 16.7 4.84 HVO_0025 thiosulfate sulfurtransferase 37.76 1 6 6 82 2.330E8 89.17 37.76 6 41 3964.19 37.76 6 41 286 32.1 4.28 HVO_1517 dolichyl-phosphate hexosyltransferase AglJ 31.68 1 6 6 52 2.296E8 37.70 28.05 5 24 2413.11 31.68 6 28 303 33.2 4.82 HVO_2559 50S ribosomal protein L22 50.98 1 5 6 52 2.287E8 60.02 41.18 5 24 4089.17 48.37 5 28 153 16.9 5.60 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 37.36 1 12 12 137 2.266E8 128.94 37.36 12 69 6871.62 37.36 12 68 447 48.5 4.56 HVO_2562 50S ribosomal protein L23 71.08 1 7 7 65 2.265E8 70.08 71.08 6 30 4581.13 71.08 7 35 83 9.4 5.48 HVO_0167 adenosylhomocysteinase 51.64 1 17 17 232 2.265E8 240.45 47.43 16 115 12842.67 51.64 17 117 428 46.6 4.39 HVO_2913 superoxide dismutase (Mn) 29.65 1 0 3 38 2.248E8 48.35 29.65 3 19 2489.65 29.65 3 19 199 22.3 4.48 HVO_A0475 superoxide dismutase (Mn) 29.50 1 0 3 38 2.248E8 48.35 29.50 3 19 2489.65 29.50 3 19 200 22.4 4.45 HVO_1245 probable disulfide bond formation protein 25.55 1 5 5 39 2.228E8 44.53 25.55 5 20 2406.94 25.55 5 19 227 24.2 4.50 HVO_2061 "probable glycosyltransferase, type 2" 22.03 1 6 6 58 2.206E8 51.75 22.03 6 28 3168.70 22.03 6 30 413 43.8 4.50 HVO_0860 SufB domain protein 36.97 1 13 13 157 2.198E8 160.33 36.97 13 79 8679.25 36.97 13 78 476 53.2 4.69 HVO_1894 conserved hypothetical protein 29.35 1 2 2 8 2.177E8 4.84 29.35 2 4 285.18 29.35 2 4 92 10.3 4.67 HVO_0988 NADH dehydrogenase-like complex subunit N 9.88 1 3 3 30 2.172E8 37.18 9.88 3 15 2214.17 9.88 3 15 506 52.2 4.64 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 51.82 1 13 13 94 2.147E8 110.74 51.82 13 47 6484.95 51.82 13 47 384 41.4 4.41 HVO_1697 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 27.78 1 24 24 180 2.137E8 202.75 27.78 24 90 11545.48 27.78 24 90 1026 111.2 4.54 HVO_1103 conserved hypothetical protein 16.67 1 4 4 22 2.135E8 17.78 13.07 3 10 1256.65 16.67 4 12 306 31.2 4.74 HVO_2053 "probable glycosyltransferase, type 1" 43.39 1 11 11 56 2.102E8 69.42 35.71 10 27 3694.48 43.39 11 29 378 41.9 4.67 HVO_0358 homoserine dehydrogenase 32.81 1 6 6 48 2.095E8 63.34 32.81 6 24 2937.53 32.81 6 24 317 32.4 4.44 HVO_0654 50S ribosomal protein L43e 39.33 1 3 3 21 2.057E8 29.91 39.33 3 11 1287.95 39.33 3 10 89 9.9 9.98 HVO_2190 gluconate permease 17.34 1 9 9 56 2.051E8 58.54 17.34 9 29 3308.51 17.34 8 27 473 49.0 4.96 HVO_0445 ABC-type transport system permease protein (probable substrate phosphate/phosphonate) 23.99 1 5 5 27 2.041E8 30.27 23.99 5 13 1394.03 23.99 5 14 321 35.5 4.81 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 42.33 1 0 23 162 2.039E8 171.36 39.97 22 80 9898.87 42.33 23 82 593 59.5 5.21 40354192 keratin 10 [Homo sapiens] 42.98 1 0 23 162 2.039E8 171.36 40.58 22 80 9898.87 42.98 23 82 584 58.8 5.16 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 53.71 1 13 13 86 2.031E8 100.92 53.71 13 43 4991.21 53.71 13 43 445 47.8 4.86 HVO_2546 50S ribosomal protein L19e 31.13 1 4 4 102 2.017E8 128.98 31.13 4 51 7613.11 31.13 4 51 151 17.3 9.98 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 32.62 1 29 31 227 2.017E8 238.49 31.17 30 113 12417.02 32.04 29 114 1033 114.3 4.45 HVO_0859 FeS assembly ATPase SufC 35.88 1 11 11 79 2.001E8 75.80 35.88 11 37 4894.44 35.88 11 42 301 33.4 4.35 HVO_1132 adenylosuccinate synthase 45.37 1 20 20 106 1.994E8 107.43 42.21 19 53 5693.20 45.37 19 53 443 48.2 4.56 HVO_2737 50S ribosomal protein L8e 43.33 1 2 2 15 1.993E8 1272.62 43.33 2 15 120 12.6 4.16 HVO_0446 ABC-type transport system ATP-binding protein (probable substrate phosphate/phosphonate) 53.93 1 10 10 76 1.982E8 82.24 50.19 9 35 4472.56 53.93 10 41 267 28.9 4.64 HVO_2150 halocyanin 24.66 1 4 4 47 1.976E8 63.09 24.66 4 24 2963.75 18.23 3 23 373 37.7 4.42 HVO_0581 "cell division protein FtsZ, type II" 48.50 1 12 12 124 1.972E8 175.78 48.50 12 62 7538.42 48.50 12 62 400 42.5 4.75 HVO_1916 Kef-type transport system (probable substrate potassium) 31.97 1 14 16 157 1.971E8 175.94 30.55 14 79 9467.26 31.97 15 78 635 66.2 4.63 HVO_2614 uridine phosphorylase 27.27 1 4 4 17 1.962E8 14.75 27.27 4 9 642.67 23.97 3 8 242 25.8 4.30 HVO_2968 phosphoglycerate dehydrogenase 47.24 1 15 15 118 1.949E8 171.72 47.24 15 59 8415.97 47.24 15 59 525 55.3 4.36 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 47.57 1 12 12 103 1.938E8 91.44 47.57 12 52 5269.50 47.57 12 51 473 50.8 4.58 HVO_2558 30S ribosomal protein S3 32.89 1 8 8 74 1.912E8 103.93 28.62 7 36 6101.02 32.89 8 38 304 33.4 4.06 HVO_0058 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 31.76 1 12 12 110 1.862E8 157.52 31.76 12 55 7768.08 31.76 12 55 444 50.2 4.84 HVO_0982 NADH dehydrogenase-like complex subunit I 27.45 1 4 4 18 1.815E8 23.43 27.45 4 10 1270.19 23.53 3 8 153 17.7 4.88 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 26.34 1 23 23 184 1.743E8 232.52 25.97 22 92 11587.15 25.42 22 92 1082 117.2 4.32 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.36 1 9 9 78 1.729E8 107.93 27.71 8 39 4221.46 30.36 9 39 415 44.4 4.41 HVO_0940 P-type transport ATPase (probable substrate copper/metal cation) 27.29 1 14 14 84 1.710E8 109.19 27.29 14 41 6034.46 27.29 14 43 828 85.9 4.53 HVO_1184 DUF1511 family protein 17.15 1 6 6 22 1.705E8 17.80 14.51 5 10 1305.41 17.15 6 12 379 40.3 4.22 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 52.08 1 9 9 66 1.698E8 87.74 52.08 9 34 3728.85 52.08 9 32 265 29.3 4.92 HVO_0944 ba3-type terminal oxidase subunit II 18.99 1 3 3 28 1.697E8 32.17 18.99 3 14 1781.01 18.99 3 14 179 19.4 4.28 HVO_B0038 ABC-type transport system ATP-binding protein (probable substrate sugar) 12.79 1 2 5 20 1.681E8 24.32 5.48 2 7 1802.06 12.79 5 13 383 41.6 4.53 HVO_2773 30S ribosomal protein S2 26.92 1 3 3 52 1.679E8 90.59 26.92 3 26 3911.82 26.92 3 26 260 28.3 4.16 HVO_3014 origin-associated GTP-binding protein OapA 56.34 1 9 10 73 1.678E8 82.89 53.05 9 36 4128.09 54.46 9 37 213 24.0 5.01 HVO_0829 peptidase S9 family protein 27.47 1 9 9 36 1.677E8 35.20 27.47 9 18 1260.35 27.47 9 18 608 67.4 4.54 HVO_2783 30S ribosomal protein S4 30.86 1 5 5 26 1.676E8 27.54 30.86 5 13 1788.14 30.86 5 13 175 20.1 5.24 HVO_0843 conserved hypothetical protein 35.66 1 7 7 38 1.664E8 27.20 35.66 7 18 2199.64 35.66 7 20 129 14.7 5.57 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 45.39 1 17 17 112 1.656E8 129.25 45.39 17 56 6492.66 40.85 16 56 661 71.0 4.35 HVO_1637 FKBP-type peptidylprolyl isomerase 33.01 1 8 8 100 1.654E8 88.90 24.51 7 47 5198.48 33.01 8 53 306 33.8 3.76 HVO_2008 archaeosine synthase 37.78 1 16 16 110 1.645E8 108.52 36.24 15 53 6174.32 37.78 16 57 585 64.9 4.81 HVO_0044 acetylglutamate kinase 9.48 1 2 2 6 1.632E8 3.75 9.48 2 3 324.32 9.48 2 3 327 33.2 4.49 HVO_C0054 hypothetical protein 28.78 1 8 9 60 1.622E8 69.37 27.62 8 29 3751.96 28.78 9 31 344 37.5 4.70 HVO_1113 "FtsZ family protein, type III" 5.40 1 0 2 11 1.610E8 8.08 5.40 2 6 489.77 5.40 2 5 389 40.8 4.89 HVO_1711 glucoamylase 39.58 1 45 45 255 1.597E8 288.59 36.47 43 127 15611.79 39.58 45 128 1511 166.1 4.64 HVO_0354 30S ribosomal protein S7 35.78 1 5 5 33 1.596E8 51.00 31.86 4 16 2328.51 35.78 5 17 204 22.6 5.14 HVO_1502 3-isopropylmalate dehydrogenase 41.36 1 10 10 90 1.572E8 118.49 32.10 8 41 6494.29 41.36 10 49 324 33.7 4.23 HVO_2646 dihydroxy-acid dehydratase 27.23 1 9 9 99 1.569E8 108.60 27.23 9 50 5447.16 27.23 9 49 584 61.8 4.42 HVO_A0451 transport protein (probable substrate arsenite/antimonite) 15.76 1 9 9 56 1.564E8 72.11 15.76 9 28 3401.84 15.76 9 28 641 68.3 4.60 HVO_2528 phytoene dehydrogenase (phytoene desaturase) 29.80 1 14 14 137 1.548E8 147.64 29.80 14 68 7887.53 29.80 14 69 500 55.8 4.56 HVO_1804 nicotinate phosphoribosyltransferase 32.99 1 9 9 58 1.542E8 80.09 29.90 8 28 3874.56 27.32 8 30 388 41.1 4.60 HVO_3000 DNA ligase (NAD) 1.72 1 1 2 4 1.510E8 5.97 1.72 2 4 699 75.8 4.50 21961227 Keratin 6B [Homo sapiens] 24.82 1 0 13 52 1.510E8 61.43 23.05 12 26 3103.94 22.87 12 26 564 60.0 8.00 HVO_0335 xanthine/uracil permease family transport protein 4.47 1 2 2 8 1.501E8 636.26 4.47 2 8 470 48.4 4.30 31074633 keratin 6L [Homo sapiens] 3.55 1 0 2 8 1.501E8 7.48 3.55 2 4 557.85 3.55 2 4 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 3.55 1 0 2 8 1.501E8 7.48 3.55 2 4 557.85 3.55 2 4 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 3.55 1 0 2 8 1.501E8 7.48 3.55 2 4 557.85 3.55 2 4 535 57.7 7.20 HVO_0881 signal peptide peptidase 32.13 1 7 8 47 1.473E8 49.97 32.13 8 24 2962.44 32.13 8 23 333 35.2 4.37 HVO_0874 beta-lactamase domain protein 32.81 1 17 18 118 1.454E8 123.95 31.09 17 59 7267.01 32.81 18 59 640 71.9 5.14 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 29.11 1 7 7 41 1.451E8 49.41 23.05 6 21 2582.92 26.22 6 20 347 36.8 4.93 HVO_2708 YfiH family protein 34.47 1 7 7 67 1.435E8 96.71 32.30 6 33 4713.42 34.47 7 34 322 35.4 4.35 HVO_2430 ABC-type transport system ATP-binding protein (probable substrate glutamine) 32.64 1 6 6 65 1.434E8 70.09 28.51 5 32 3674.68 32.64 6 33 242 26.6 4.88 HVO_2384 CBS domain protein 23.16 1 5 5 38 1.410E8 47.95 23.16 5 19 2170.47 23.16 5 19 380 42.5 5.01 HVO_A0331 D-galactonate dehydratase 55.99 1 12 12 94 1.401E8 95.91 55.99 12 47 5147.52 55.99 12 47 384 42.8 4.83 HVO_2016 conserved hypothetical protein 28.09 1 9 9 96 1.399E8 125.67 28.09 9 49 6632.12 28.09 9 47 299 31.2 4.70 HVO_2770 conserved hypothetical protein 32.50 1 10 10 51 1.399E8 44.57 32.50 10 26 2859.93 32.50 10 25 320 35.7 5.15 HVO_1454 aspartate carbamoyltransferase catalytic subunit 67.11 1 13 13 100 1.397E8 117.78 67.11 13 50 6220.75 67.11 13 50 304 33.7 4.92 HVO_0717 "cell division protein FtsZ, type I" 24.80 1 7 7 72 1.391E8 105.14 24.80 7 36 5797.79 24.80 7 36 379 39.8 4.40 HVO_B0200 malate synthase 25.69 1 6 6 35 1.387E8 54.58 25.69 6 17 2082.43 25.69 6 18 436 48.3 4.30 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 44.43 1 15 15 105 1.378E8 117.18 44.43 15 52 6344.21 44.43 15 53 592 66.6 4.61 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 28.69 1 17 17 110 1.356E8 93.40 26.11 15 54 5645.20 28.69 17 56 697 74.5 4.13 HVO_0087 porphobilinogen synthase 46.79 1 10 10 86 1.349E8 81.50 46.79 10 42 3924.33 46.79 10 44 327 35.3 4.72 HVO_1751 P-type transport ATPase (probable substrate copper/metal cation) 23.58 1 17 17 117 1.328E8 137.09 23.58 17 59 5975.38 23.58 17 58 861 89.9 4.40 HVO_1710 alpha amylase 17.87 1 10 12 93 1.320E8 83.41 17.13 11 45 5440.43 17.87 12 48 677 75.0 4.45 HVO_2431 ABC-type transport system permease protein (probable substrate glutamine) 27.17 1 5 5 39 1.318E8 32.31 17.75 4 18 2280.63 27.17 5 21 276 29.6 5.15 HVO_1510 2-isopropylmalate synthase 7.50 1 2 2 14 1.309E8 17.99 7.50 2 7 1137.42 7.50 2 7 440 47.7 4.82 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 32.20 1 4 15 72 1.293E8 50.04 32.20 15 36 3291.59 32.20 14 36 472 51.6 5.16 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 25.58 1 2 12 68 1.293E8 53.29 25.58 12 34 3301.90 25.58 11 34 473 51.2 5.05 HVO_B0153_A conserved hypothetical protein 5.93 1 2 2 9 1.277E8 8.34 5.93 2 5 250.73 5.93 2 4 388 41.3 9.45 HVO_1981 hypothetical protein 17.77 1 3 3 371 1.262E8 516.20 17.77 3 187 29547.91 17.77 3 184 197 20.3 4.01 HVO_1306 chorismate synthase 37.40 1 10 10 114 1.250E8 161.78 37.40 10 57 6496.71 37.40 10 57 385 41.9 4.83 HVO_3002 ABC-type transport system ATP-binding protein 38.04 1 9 9 78 1.246E8 86.84 34.97 8 38 4136.34 38.04 9 40 326 34.7 4.31 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 26.42 1 0 14 45 1.241E8 47.43 23.05 12 22 2384.45 24.47 13 23 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 23.40 1 0 13 46 1.241E8 49.44 21.81 12 23 2634.30 21.45 12 23 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 23.40 1 0 13 46 1.241E8 49.44 21.81 12 23 2634.30 21.45 12 23 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 23.40 1 0 13 43 1.241E8 45.11 20.04 11 21 2355.60 21.45 12 22 564 60.0 7.72 386849 keratin type II 22.91 1 0 12 40 1.241E8 43.10 21.31 11 20 2128.66 20.96 11 20 563 59.9 7.94 HVO_0996 DUF21/CBS domain protein 38.15 1 12 12 47 1.235E8 52.67 35.97 11 23 3113.07 38.15 12 24 367 39.1 4.51 HVO_2031 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 13.65 1 2 2 14 1.231E8 26.37 13.65 2 7 1178.90 13.65 2 7 403 42.4 3.99 HVO_1453 glutamate dehydrogenase (NADP) 32.37 1 10 10 70 1.227E8 52.10 26.62 9 33 4192.87 32.37 10 37 417 45.7 4.49 HVO_2969 threonine synthase 42.96 1 11 11 64 1.215E8 74.97 42.96 11 31 3659.44 42.96 11 33 419 44.4 4.49 HVO_0824 "probable glycosyltransferase, type 1" 38.07 1 9 9 44 1.177E8 47.85 32.95 8 21 2659.57 38.07 9 23 352 39.6 5.08 HVO_1082 homolog to orotate phosphoribosyltransferase 62.38 1 9 9 44 1.177E8 52.83 55.24 8 21 2677.60 62.38 9 23 210 22.3 4.42 HVO_0002 signal peptidase I 29.62 1 6 6 25 1.173E8 22.96 25.78 5 12 1327.52 29.62 6 13 287 30.3 4.60 HVO_1110 ABC-type transport system periplasmic substrate-binding protein (probable substrate cobalamin) 15.18 1 3 3 48 1.165E8 77.46 15.18 3 24 3660.50 15.18 3 24 382 39.6 4.25 HVO_0310 A-type ATP synthase subunit H 69.09 1 5 5 48 1.164E8 60.34 69.09 5 24 2717.45 69.09 5 24 110 12.5 4.03 HVO_0348 DNA-directed RNA polymerase subunit B' 50.41 1 21 21 128 1.146E8 131.19 50.08 20 62 6816.27 45.81 19 66 609 67.7 4.92 4557890 keratin 5 [Homo sapiens] 24.75 1 0 15 54 1.115E8 49.05 23.22 14 27 2606.34 24.75 15 27 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 24.75 1 0 15 54 1.115E8 49.05 23.22 14 27 2606.34 24.75 15 27 590 62.4 8.06 HVO_0536 ferritin 48.86 1 4 4 62 1.113E8 71.39 48.86 4 31 2994.10 48.86 4 31 176 19.9 4.50 HVO_1346 GTP-binding protein HflX 56.35 1 20 20 114 1.106E8 117.91 56.35 20 57 6218.99 56.35 20 57 433 48.2 4.73 HVO_1300 triosephosphate isomerase 20.09 1 4 4 22 1.105E8 21.37 20.09 4 11 1221.96 20.09 4 11 214 21.3 4.26 HVO_0711 conserved hypothetical protein 28.70 1 5 5 38 1.102E8 29.92 23.61 4 17 2587.01 28.70 5 21 216 23.1 3.81 HVO_A0205 CRISPR-associated endoribonuclease Cas6 44.49 1 11 11 72 1.096E8 82.45 44.49 11 36 3933.66 44.49 11 36 272 31.0 5.44 HVO_0357 ACT domain protein 30.16 1 5 5 24 1.091E8 27.04 30.16 5 12 1395.35 30.16 5 12 189 20.2 4.59 HVO_0880 conserved hypothetical protein 62.21 1 19 19 135 1.086E8 136.40 59.28 18 66 7369.41 62.21 19 69 307 36.3 4.74 HVO_1870 probable metalloprotease 14.96 1 7 7 51 1.067E8 47.01 11.26 6 25 3209.01 14.96 7 26 595 62.0 4.84 HVO_2695 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 33.59 1 9 9 92 1.063E8 123.79 33.59 9 46 5789.45 33.59 9 46 512 55.4 4.42 HVO_A0049 DUF21/CBS domain protein 32.14 1 10 10 67 1.060E8 77.08 32.14 10 35 3728.11 32.14 10 32 448 48.8 4.31 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 34.29 1 11 11 66 1.058E8 76.62 32.38 10 33 3799.88 34.29 11 33 525 56.4 4.40 31559815 keratin 25B [Homo sapiens] 5.98 1 1 2 5 1.056E8 4.14 5.98 2 5 468 51.8 4.96 HVO_2048 "probable glycosyltransferase, type 1" 46.80 1 15 15 74 1.053E8 73.41 46.80 15 36 3818.56 46.80 15 38 359 40.5 5.30 HVO_1006 ABC-type transport system ATP-binding protein 36.91 1 6 7 51 1.035E8 71.29 35.65 6 25 2940.16 36.91 7 26 317 32.7 4.39 HVO_0237 UPF0761 family protein 13.26 1 5 5 34 1.035E8 47.88 13.26 5 17 2628.64 13.26 5 17 445 46.7 5.14 HVO_2191 formyltetrahydrofolate deformylase 41.28 1 11 11 70 1.033E8 79.99 41.28 11 35 4291.47 41.28 11 35 327 36.2 4.63 109255249 keratin 4 [Homo sapiens] 2.69 1 0 2 8 1.032E8 7.39 2.69 2 4 496.57 2.69 2 4 594 63.9 8.25 HVO_1412 diphosphomevalonate decarboxylase 21.60 1 4 4 17 1.030E8 11.74 21.60 4 9 837.90 8.95 3 8 324 35.4 4.78 HVO_0102 HtpX-like protease 11.60 1 3 4 11 1.014E8 3.88 11.60 4 6 487.75 10.24 3 5 293 32.7 7.50 HVO_A0206 CRISPR-associated protein Cas8b 36.82 1 19 19 113 1.008E8 114.36 32.22 17 55 5779.03 36.82 19 58 717 79.3 4.60 HVO_2169 conserved hypothetical protein 22.25 1 5 5 21 9.954E7 28.63 22.25 5 10 1455.18 22.25 5 11 346 36.5 4.39 HVO_0054 glycine--tRNA ligase 18.18 1 7 7 44 9.816E7 60.01 15.82 6 21 2755.81 18.18 7 23 594 64.9 4.21 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 25.51 1 9 11 57 9.801E7 51.70 23.12 9 28 2827.02 25.51 11 29 584 63.3 4.79 HVO_0307 conserved hypothetical protein 28.73 1 10 10 61 9.798E7 77.27 28.73 10 30 3607.38 28.73 10 31 463 49.0 4.88 HVO_1165 mechanosensitive channel protein MscS 35.43 1 7 7 50 9.787E7 54.56 35.43 7 25 2530.23 35.43 7 25 302 32.6 4.91 31559823 keratin 25D [Homo sapiens] 4.96 1 0 3 16 9.719E7 4.14 4.96 3 8 855.79 4.96 3 8 464 50.6 5.47 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 13.89 1 0 8 47 9.696E7 36.64 13.89 8 24 2122.84 13.89 7 23 432 48.1 5.02 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 8.99 1 0 6 31 9.696E7 20.15 8.99 6 16 1299.81 8.99 5 15 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 8.99 1 0 6 31 9.696E7 20.15 8.99 6 16 1299.81 8.99 5 15 456 49.2 4.77 HVO_0685 DUF3100 family protein 22.45 1 6 6 24 9.532E7 24.95 22.45 6 13 1216.08 18.71 5 11 294 30.1 5.29 HVO_1168 "probable glycosyltransferase, type 1" 33.14 1 9 9 34 9.386E7 45.71 33.14 9 17 2241.51 33.14 9 17 353 39.1 5.01 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 65 9.359E7 70.77 40.00 4 33 2976.65 40.00 4 32 130 14.1 4.79 HVO_1523_A glycosyltransferase AglE 33.22 1 8 8 54 9.355E7 35.48 25.99 7 23 3020.55 33.22 8 31 304 33.8 7.08 HVO_A0428 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 50.97 1 19 19 129 9.292E7 137.67 44.09 18 65 7347.58 50.97 19 64 567 62.4 4.70 HVO_0236 tRNA (guanine(26)-N(2))-dimethyltransferase 9.57 1 3 3 7 9.151E7 6.10 9.57 3 4 255.85 4.52 2 3 376 40.9 4.97 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 16 9.148E7 20.41 3.63 2 8 872.66 3.63 2 8 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.59 1 0 2 16 9.148E7 20.41 3.59 2 8 872.66 3.59 2 8 529 57.8 7.71 28173564 keratin 6 irs3 [Homo sapiens] 3.52 1 0 2 16 9.148E7 20.41 3.52 2 8 872.66 3.52 2 8 540 58.9 7.23 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 48.77 1 11 11 98 9.136E7 101.27 40.74 10 48 6064.09 48.77 11 50 324 36.6 4.68 HVO_A0174 protein translocase subunit SecY 2.66 1 0 2 9 9.126E7 4.13 2.66 2 9 488 51.9 7.06 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 32.71 1 5 5 25 9.103E7 14.84 32.71 5 13 1091.67 32.71 5 12 269 28.3 4.49 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 15.67 1 2 4 32 9.093E7 40.89 15.67 4 15 2460.38 15.67 4 17 383 41.9 4.21 HVO_1496 phosphotransferase system component I 16.99 1 6 6 30 9.092E7 38.89 16.99 6 15 1966.37 16.99 6 15 565 60.3 4.21 HVO_0506 ABC-type transport system ATP-binding/permease protein 17.83 1 7 7 24 9.023E7 13.80 17.83 7 12 979.67 14.88 6 12 645 71.7 4.59 HVO_2456 anthranilate phosphoribosyltransferase 25.98 1 6 6 63 9.010E7 101.98 25.98 6 33 5003.01 25.98 6 30 331 33.8 4.35 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 32.55 1 0 12 39 8.893E7 43.46 27.60 10 19 2201.55 29.69 11 20 384 42.4 5.40 HVO_2013 "FtsZ family protein, type III" 48.48 1 9 9 81 8.833E7 98.62 48.48 9 40 4791.03 48.48 9 41 394 41.5 4.61 HVO_0826 peptidase M42 family protein 30.75 1 5 5 44 8.828E7 63.58 30.75 5 22 2504.16 30.75 5 22 348 37.7 4.54 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 8.00 1 0 4 19 8.763E7 9.17 8.00 4 10 781.30 5.75 3 9 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 8.00 1 0 4 19 8.763E7 9.17 8.00 4 10 781.30 5.75 3 9 400 44.1 5.14 HVO_0809 methionine--tRNA ligase 33.78 1 17 17 98 8.690E7 108.42 33.78 17 49 5882.10 33.78 17 49 740 81.9 4.37 HVO_2624 CTP synthase 26.78 1 9 9 49 8.641E7 43.84 24.77 8 23 2709.99 26.78 9 26 549 60.8 4.70 HVO_2811 succinate dehydrogenase subunit C (cytochrome b-556) 10.69 1 2 2 6 8.631E7 603.51 10.69 2 6 131 14.4 6.79 HVO_2069 RND superfamily permease 28.13 1 14 14 108 8.611E7 117.46 28.13 14 53 6077.09 28.13 14 55 839 89.4 4.42 HVO_2410 UPF0753 family protein 26.79 1 12 12 64 8.574E7 85.47 26.79 12 33 3989.36 22.22 10 31 810 86.9 4.34 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 31.10 1 10 10 56 8.561E7 70.88 31.10 10 28 3492.56 31.10 10 28 492 52.1 4.83 HVO_1478 transcription initiation factor TFB 41.96 1 7 12 77 8.555E7 78.26 41.96 12 39 4292.13 36.59 11 38 317 35.7 5.47 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 38.63 1 10 10 55 8.520E7 56.62 38.63 10 28 2965.19 38.63 10 27 453 47.5 4.63 HVO_0552 DNA mismatch repair protein MutS 34.09 1 22 22 105 8.516E7 121.28 34.09 22 53 6888.12 32.03 21 52 924 99.2 4.65 HVO_2882 DUF4013 family protein 11.67 1 2 2 22 8.501E7 26.06 11.67 2 11 1319.98 11.67 2 11 240 25.4 4.55 18266794 "Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8)" 8.77 1 0 2 4 8.287E7 0.00 8.77 2 4 456 50.5 4.84 15431318 type I hair keratin 8 [Homo sapiens] 8.77 1 0 2 4 8.287E7 0.00 8.77 2 4 456 50.4 4.84 HVO_B0149 oleate hydratase 28.71 1 10 11 59 8.248E7 40.26 22.70 10 31 2384.95 28.71 11 28 533 60.1 4.64 HVO_0743 probable phosphodiesterase 39.20 1 14 14 72 8.238E7 61.55 28.95 12 35 3602.17 39.20 14 37 449 50.5 4.56 HVO_1573 DNA gyrase subunit A 27.38 1 16 16 76 8.225E7 68.93 25.17 15 38 3724.12 22.74 14 38 862 94.8 4.56 HVO_1176 conserved hypothetical protein 20.72 1 6 6 29 8.177E7 26.46 20.72 6 15 1222.61 20.32 5 14 251 27.7 5.11 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 30.32 1 8 8 36 8.170E7 36.94 30.32 8 18 1680.70 30.32 8 18 376 41.8 4.91 HVO_0601 homoserine dehydrogenase 41.14 1 5 5 36 8.043E7 50.81 41.14 5 18 2260.52 41.14 5 18 316 32.2 4.25 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 56.19 1 5 5 35 8.037E7 37.03 45.36 4 16 2673.24 56.19 5 19 194 20.7 4.12 HVO_1591 conserved hypothetical protein 35.61 1 6 6 39 8.035E7 49.20 35.61 6 20 2618.87 35.61 6 19 264 28.7 5.50 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 31.80 1 9 9 69 8.032E7 77.58 28.13 8 33 3952.57 31.80 9 36 327 36.0 4.73 HVO_1504 3-isopropylmalate dehydratase large subunit 26.00 1 10 10 44 7.944E7 56.78 21.99 9 21 3095.10 26.00 10 23 473 51.6 4.55 HVO_2688 TrmB family transcription regulator 27.48 1 7 7 32 7.937E7 41.52 27.48 7 16 2504.85 27.48 7 16 353 39.3 4.58 HVO_2068 "FtsZ family protein, type III" 29.46 1 7 8 43 7.908E7 52.74 29.46 8 22 2919.46 28.38 7 21 370 38.7 4.49 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 31.89 1 10 10 38 7.871E7 34.52 31.89 10 19 1798.24 31.89 10 19 370 41.9 4.48 HVO_0061 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 24.07 1 5 5 39 7.804E7 65.06 24.07 5 20 2987.32 18.62 4 19 349 38.8 6.18 HVO_2521 DUF21/CBS domain protein 12.03 1 3 3 16 7.780E7 24.00 12.03 3 8 1489.30 12.03 3 8 349 38.4 4.42 HVO_1191 proline dehydrogenase 41.94 1 6 6 19 7.707E7 13.92 41.94 6 10 915.30 31.90 5 9 279 31.0 5.02 HVO_1570 DNA topoisomerase VI subunit A 37.43 1 8 8 42 7.665E7 53.65 34.70 7 20 2536.92 37.43 8 22 366 41.8 4.63 HVO_1465 naphthoate synthase 46.56 1 11 11 64 7.578E7 75.14 37.70 9 31 3481.01 43.61 10 33 305 33.9 4.83 HVO_2082 conserved hypothetical protein 18.69 1 4 4 40 7.568E7 51.25 18.69 4 20 2452.02 18.69 4 20 396 40.9 4.50 HVO_0393 UvrABC system protein A 51.17 1 34 34 175 7.543E7 198.86 51.17 34 88 9272.01 51.17 34 87 983 108.6 4.82 HVO_2081 pectin lyase domain protein 30.84 1 19 19 112 7.540E7 136.74 30.84 19 56 7138.99 30.84 19 56 1041 109.7 5.34 HVO_0733 transcription initiation factor TFB 15.95 1 1 6 24 7.490E7 19.64 15.95 6 12 1150.86 15.95 6 12 326 37.2 6.00 HVO_1985 ABC-type transport system ATP-binding protein 38.49 1 7 7 35 7.483E7 37.06 38.49 7 18 2170.66 30.60 6 17 317 35.0 4.54 HVO_2168 AAA-type ATPase (MoxR subfamily) 51.06 1 11 11 55 7.432E7 51.09 42.86 10 27 2667.24 51.06 11 28 329 35.9 4.54 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 26.42 1 5 5 38 7.352E7 44.50 26.42 5 19 1964.43 26.42 5 19 386 42.1 4.49 HVO_0350 DNA-directed RNA polymerase subunit A'' 22.91 1 8 8 44 7.294E7 53.28 22.91 8 22 2553.72 22.91 8 22 419 46.1 4.35 HVO_A0339 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 35.37 1 13 13 86 7.288E7 98.00 35.37 13 43 5028.65 35.37 13 43 557 61.2 4.39 HVO_0206 alanine--tRNA ligase 33.19 1 21 21 150 7.243E7 163.24 30.26 18 73 9184.82 33.19 21 77 922 102.4 4.54 HVO_0244 transport protein (probable substrate zinc/cadmium) 8.28 1 2 2 10 7.239E7 12.22 8.28 2 5 591.42 8.28 2 5 314 34.0 4.60 HVO_1901 translation initiation factor aIF-2 gamma subunit 19.71 1 7 7 53 7.233E7 59.22 19.71 7 27 3019.85 19.71 7 26 411 43.9 4.36 HVO_0570 histidine kinase 30.20 1 8 8 44 7.221E7 35.41 30.20 8 21 2136.48 30.20 8 23 351 37.0 5.11 HVO_1944 conserved hypothetical protein 34.62 1 7 8 56 7.207E7 69.13 34.62 8 28 2989.18 26.68 6 28 416 43.0 4.22 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 39.58 1 7 7 83 7.188E7 116.17 34.23 6 39 5719.31 39.58 7 44 336 36.8 4.12 HVO_1528 glycosyltransferase AglI 25.42 1 6 6 30 7.181E7 31.26 25.42 6 15 1643.43 25.42 6 15 295 32.8 4.72 HVO_0845 conserved hypothetical protein 33.70 1 5 5 43 7.108E7 60.09 25.00 4 21 2463.85 33.70 5 22 276 30.0 4.16 HVO_2205 arNOG06768 family NADH-binding domain protein 55.81 1 11 11 102 7.066E7 138.82 55.81 11 51 6226.96 55.81 11 51 301 32.0 5.00 HVO_1571 DNA topoisomerase VI subunit B 27.44 1 15 15 88 7.065E7 109.67 25.06 14 43 6244.48 27.44 15 45 798 87.4 4.73 HVO_B0153 CapB domain protein 22.16 1 8 8 36 7.048E7 38.24 22.16 8 18 2232.50 22.16 8 18 546 60.7 4.87 HVO_B0093 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 26.70 1 11 11 79 7.044E7 99.34 26.70 11 40 4415.71 26.70 11 39 618 69.1 4.45 HVO_1824 conserved hypothetical protein 23.31 1 8 9 59 7.002E7 72.21 23.31 8 29 3858.61 23.31 9 30 429 47.4 4.20 HVO_1241 SCO1/SenC/PrrC family protein 19.73 1 2 2 21 6.991E7 21.65 19.73 2 12 951.70 19.73 2 9 223 24.6 4.45 HVO_2700 AAA-type ATPase (CDC48 subfamily) 37.93 1 20 21 126 6.945E7 140.29 37.93 21 63 7135.62 37.93 21 63 754 82.8 4.75 HVO_0541 aconitate hydratase 30.49 1 17 17 76 6.927E7 76.14 30.49 17 39 4171.78 25.05 15 37 938 102.1 4.40 HVO_2739 50S ribosomal protein L24e 36.36 1 3 3 17 6.835E7 8.42 36.36 3 8 794.38 36.36 3 9 66 7.5 5.17 31559819 keratin 25C [Homo sapiens] 3.49 1 0 2 10 6.698E7 4.14 3.49 2 5 593.84 3.49 2 5 459 49.8 5.14 HVO_0721 PHP domain protein 42.52 1 7 7 30 6.688E7 24.93 42.52 7 15 1377.29 42.52 7 15 254 28.2 5.97 HVO_0306 conserved hypothetical protein 28.06 1 8 8 36 6.679E7 42.03 28.06 8 18 2295.24 28.06 8 18 392 42.1 4.30 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 47.18 1 16 16 74 6.605E7 69.10 43.95 14 35 3660.59 47.18 16 39 496 55.0 4.53 HVO_2020 DUF502 family protein 22.10 1 4 4 39 6.576E7 52.63 22.10 4 19 3022.50 22.10 4 20 267 29.4 4.35 HVO_0105 FAD-dependent oxidoreductase 33.07 1 10 10 64 6.546E7 67.31 33.07 10 32 3322.18 33.07 10 32 381 41.8 4.70 HVO_1547 isoleucine--tRNA ligase 16.87 1 11 11 39 6.521E7 44.15 16.87 11 20 1808.24 14.00 10 19 1043 117.9 4.30 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 26.39 1 7 7 35 6.510E7 35.54 26.39 7 19 1546.94 23.06 6 16 360 39.6 4.39 HVO_1025 acetyl-CoA C-acyltransferase 21.41 1 6 6 36 6.492E7 46.62 21.41 6 18 2098.52 21.41 6 18 383 40.7 4.56 HVO_1967 glucose-6-phosphate isomerase 33.72 1 9 9 66 6.477E7 86.46 33.72 9 33 4455.07 33.72 9 33 430 45.6 4.40 HVO_1094 ribonuclease P protein component 3 43.72 1 8 8 33 6.477E7 30.82 43.72 8 16 1759.38 43.72 8 17 231 25.6 5.31 HVO_2871 pyridoxal phosphate-dependent aminotransferase 10.00 1 2 2 2 6.440E7 133.98 10.00 2 2 450 49.1 4.70 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 55.29 1 0 5 29 6.437E7 15.78 55.29 5 14 1449.96 55.29 5 15 85 10.0 5.94 HVO_1760 ABC-type transport system ATP-binding protein (probable substrate iron-III) 44.37 1 8 9 54 6.432E7 51.66 44.37 9 27 3198.02 44.37 9 27 293 32.4 4.58 28372503 keratin protein K6irs [Homo sapiens] 7.83 1 0 4 25 6.420E7 30.56 7.83 4 12 1394.91 7.83 4 13 511 55.8 6.89 18031720 keratin protein K6irs [Homo sapiens] 7.84 1 0 4 25 6.420E7 30.56 7.84 4 12 1394.91 7.84 4 13 510 55.7 6.89 HVO_0008 aspartate kinase 24.23 1 5 5 29 6.406E7 23.34 24.23 5 14 1557.74 24.23 5 15 392 41.7 4.46 HVO_C0042 helicase domain protein 19.86 1 19 19 69 6.394E7 67.36 19.86 19 34 3367.66 18.37 18 35 1274 144.4 4.67 HVO_1532 DUF368 family protein 11.18 1 3 3 15 6.391E7 21.00 11.18 3 8 1009.62 11.18 3 7 322 32.8 6.54 HVO_1479 CHP03663 family protein 14.08 1 5 6 21 6.384E7 27.07 14.08 6 11 1231.12 13.35 5 10 547 57.3 5.99 HVO_1554 TraB family protein 18.72 1 7 7 31 6.383E7 25.71 14.80 6 15 1185.68 18.72 7 16 561 59.0 4.58 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 30.49 1 10 10 72 6.376E7 98.19 30.49 10 36 5314.45 30.49 10 36 364 39.3 4.35 HVO_2302 ubiquinone biosynthesis protein UbiB 25.09 1 11 11 48 6.356E7 50.06 25.09 11 24 2545.95 25.09 11 24 558 63.0 4.69 HVO_0347 DNA-directed RNA polymerase subunit B'' 43.57 1 18 18 129 6.354E7 112.76 43.57 18 64 5925.33 43.57 18 65 521 58.9 5.00 HVO_2500 transport protein (probable substrate cationic amino acids) 17.11 1 9 9 45 6.254E7 48.25 17.11 9 21 2446.59 17.11 9 24 748 78.6 4.61 HVO_B0115 fumarylacetoacetase family protein 28.62 1 5 5 15 6.238E7 12.82 28.62 5 8 717.14 28.62 5 7 283 30.3 4.21 HVO_0870 proline--tRNA ligase 49.18 1 14 14 98 6.217E7 84.20 46.72 13 46 5570.36 49.18 14 52 488 54.9 4.44 HVO_A0619 conserved hypothetical protein 24.34 1 7 7 34 6.155E7 37.03 24.34 7 17 1764.04 24.34 7 17 452 48.2 4.68 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 31.58 1 4 5 25 6.138E7 24.75 31.58 5 13 1469.51 29.47 4 12 190 20.6 4.30 HVO_0865 FkbM family methyltransferase 21.83 1 4 4 22 6.129E7 29.07 21.83 4 11 1327.57 21.83 4 11 252 27.7 5.49 HVO_0951 hypothetical protein 17.42 1 5 5 14 6.113E7 15.37 17.42 5 7 866.19 17.42 5 7 333 38.1 4.69 HVO_0975 homolog to membrane-bound mannosyltransferase 11.99 1 6 6 26 6.109E7 27.50 10.62 5 12 1466.26 11.99 6 14 584 62.8 4.97 HVO_2425 GNAT family acetyltransferase 43.98 1 7 8 44 6.107E7 41.00 43.98 8 22 2253.36 37.04 6 22 216 24.4 4.54 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 34.39 1 11 11 49 6.087E7 61.01 28.69 9 23 2945.34 34.39 11 26 474 53.4 4.59 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 25.40 1 5 5 55 6.057E7 79.73 25.40 5 27 4088.05 25.40 5 28 252 26.0 4.39 HVO_1513 conserved hypothetical protein 15.79 1 2 3 15 6.034E7 22.08 15.79 3 8 968.30 14.04 2 7 228 25.1 5.07 HVO_1921 serine--tRNA ligase 44.35 1 16 17 86 6.025E7 89.32 44.35 17 44 4596.56 43.48 16 42 460 52.0 4.46 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 36.34 1 11 11 62 5.964E7 83.68 36.34 11 31 3768.47 36.34 11 31 454 48.5 4.46 HVO_1917 acyl-CoA synthetase 34.38 1 15 16 72 5.958E7 82.52 33.78 15 36 3786.59 34.38 16 36 666 74.0 4.78 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 33.57 1 6 6 34 5.940E7 35.77 33.57 6 17 1964.04 33.57 6 17 280 30.1 4.44 HVO_2618 TrkA-C domain protein 26.75 1 10 10 47 5.928E7 28.82 26.75 10 24 2112.32 26.75 9 23 501 50.6 4.49 HVO_2749 50S ribosomal protein L21e 20.83 1 2 2 9 5.889E7 8.11 20.83 2 5 462.97 20.83 2 4 96 10.6 10.95 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 33.42 1 8 8 55 5.863E7 68.86 33.42 8 28 2744.81 33.42 8 27 386 40.0 4.68 HVO_1589 molecular chaperone DnaJ 15.06 1 6 6 31 5.835E7 14.76 11.95 5 15 1332.51 15.06 6 16 385 41.9 4.97 HVO_2300 translation initiation factor aIF-5A 24.19 1 2 2 8 5.818E7 5.04 24.19 2 4 393.19 24.19 2 4 124 14.2 5.22 HVO_B0292 ABC-type transport system periplasmic substrate-binding protein (probable substrate glycerol-3-phosphate) 22.70 1 8 8 44 5.813E7 46.91 22.70 8 22 2555.02 22.70 8 22 489 52.6 4.36 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 52.68 1 10 10 58 5.806E7 64.15 52.68 10 28 2957.38 52.68 10 30 355 38.2 4.68 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 37.39 1 10 11 52 5.802E7 47.71 37.39 10 25 2519.45 37.39 11 27 345 36.9 4.68 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 21.12 1 11 11 51 5.796E7 62.33 21.12 11 25 3041.97 21.12 11 26 838 89.1 4.65 HVO_0330 DUF502 family protein 9.35 1 2 2 10 5.789E7 11.66 9.35 2 5 617.36 9.35 2 5 214 23.3 4.67 HVO_0798 dolichyl-phosphate mannosyltransferase AglD 10.42 1 6 7 27 5.779E7 16.61 10.42 7 13 1282.73 10.42 7 14 624 66.9 5.19 HVO_2781 DNA-directed RNA polymerase subunit D 26.64 1 5 5 23 5.764E7 24.74 22.39 4 11 1513.57 26.64 5 12 259 28.1 4.32 HVO_B0363 dimethylsulfoxide reductase subunit A (reductase subunit) 39.74 1 23 24 106 5.740E7 122.58 39.74 24 53 6227.89 37.01 23 53 843 92.3 4.79 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 26.89 1 7 7 30 5.729E7 22.40 21.97 6 14 1670.72 26.89 7 16 305 33.8 4.74 HVO_1373 acyl-CoA dehydrogenase 33.42 1 8 8 62 5.696E7 67.76 33.42 8 31 3454.19 33.42 8 31 383 42.5 4.61 HVO_2707 GFO family oxidoreductase 22.58 1 7 7 46 5.683E7 56.88 22.58 7 23 2725.06 22.58 7 23 372 41.0 4.55 HVO_0214 L-lactate dehydrogenase 15.31 1 4 4 18 5.626E7 14.21 12.50 3 8 836.20 15.31 4 10 320 34.5 4.49 HVO_1459 ThuA family protein 24.37 1 3 4 27 5.605E7 26.36 24.37 4 13 1451.15 22.69 3 14 238 26.8 4.67 HVO_0229 conserved hypothetical protein 6.27 1 2 2 3 5.556E7 472.13 6.27 2 3 271 27.3 4.68 HVO_1034 type IV pilus biogenesis complex ATPase subunit 33.87 1 13 13 60 5.540E7 63.24 33.87 13 28 3050.42 33.87 13 32 564 64.2 4.75 HVO_2606 PQQ repeat protein 24.94 1 8 8 51 5.536E7 40.71 24.94 8 24 2516.29 24.94 8 27 437 46.9 4.81 HVO_2161 conserved hypothetical protein 7.52 1 3 3 36 5.530E7 49.26 7.52 3 18 2276.14 7.52 3 18 359 36.7 3.88 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 20.48 1 18 18 77 5.515E7 61.67 20.48 18 37 3810.80 19.47 17 40 1284 141.2 4.35 HVO_1749 conserved hypothetical protein 10.92 1 2 2 40 5.471E7 60.24 10.92 2 20 3147.54 10.92 2 20 284 31.0 3.97 HVO_0718 protein translocase subunit SecE 40.35 1 2 2 6 5.428E7 6.88 40.35 2 3 314.02 40.35 2 3 57 6.2 8.62 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 45.91 1 8 8 40 5.394E7 48.72 45.91 8 20 2618.36 45.91 8 20 281 30.6 4.59 HVO_1130 conserved hypothetical protein 47.15 1 5 5 48 5.392E7 56.48 47.15 5 24 2446.13 47.15 5 24 193 20.1 4.78 HVO_2316 serpin family protein 21.41 1 8 8 45 5.326E7 50.65 21.41 8 22 2836.27 21.41 8 23 453 48.7 4.25 HVO_1066 Mrp-type sodium/proton antiporter system subunit D1 12.21 1 5 5 28 5.322E7 26.17 12.21 5 14 1378.96 12.21 5 14 565 58.1 5.25 HVO_1294 GMC family oxidoreductase 18.06 1 6 6 26 5.295E7 27.50 18.06 6 13 1343.28 18.06 6 13 526 56.7 4.94 HVO_1546 dihydroxyacetone kinase subunit DhaK 27.41 1 8 8 48 5.277E7 63.03 27.41 8 24 2675.97 27.41 8 24 332 34.8 4.22 HVO_B0318 ABC-type transport system periplasmic substrate-binding protein (substrate glucose) 7.93 1 3 3 12 5.261E7 6.53 7.93 3 6 598.74 7.93 3 6 391 42.4 3.95 HVO_0319 A-type ATP synthase subunit D 33.19 1 9 9 54 5.248E7 45.94 33.19 9 26 3059.44 33.19 9 28 235 26.7 4.72 HVO_0420 transducer protein MpcT 29.28 1 8 8 74 5.232E7 104.44 29.28 8 38 4252.37 29.28 8 36 543 57.1 4.12 HVO_2122 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 19.29 1 5 5 18 5.232E7 25.45 19.29 5 9 1381.38 19.29 5 9 368 40.0 4.63 HVO_0116 50S ribosomal protein L31e 22.83 1 2 2 5 5.229E7 1.61 22.83 2 3 114.00 22.83 2 2 92 10.5 5.49 HVO_A0611 ABC-type transport system periplasmic substrate-binding protein (probable substrate zinc) 36.42 1 7 7 32 5.190E7 30.77 36.42 7 16 1335.85 36.42 7 16 335 35.9 4.39 HVO_2943 dihydroorotate dehydrogenase (quinone) 25.93 1 5 5 36 5.188E7 39.32 25.93 5 18 2215.48 25.93 5 18 351 37.4 4.72 HVO_1264 conserved hypothetical protein 31.34 1 4 4 26 5.186E7 28.74 31.34 4 13 1731.88 31.34 4 13 217 23.4 4.22 4504919 keratin 8 [Homo sapiens] 4.76 1 0 3 12 5.152E7 8.26 4.76 3 6 548.48 4.76 3 6 483 53.7 5.59 HVO_1707 ABC-type transport system ATP-binding protein (probable substrate iron-III) 22.37 1 5 5 37 5.124E7 29.97 22.37 5 18 1665.03 22.37 5 19 389 41.9 4.40 HVO_0415 repair helicase 26.30 1 10 11 42 5.123E7 52.48 23.21 10 22 2346.00 21.27 9 20 616 69.6 4.70 HVO_A0627 conserved hypothetical protein 16.38 1 4 4 23 5.109E7 26.22 16.38 4 12 1082.69 16.38 4 11 354 38.1 4.70 HVO_1727 TATA-binding transcription initiation factor 24.73 1 4 4 24 5.079E7 25.58 24.73 4 12 1630.06 24.73 4 12 186 19.9 4.36 HVO_A0624 P-type transport ATPase (probable substrate zinc/cadmium) 17.21 1 10 10 53 4.990E7 57.39 17.21 10 27 3094.35 17.21 10 26 895 92.5 4.42 HVO_0941 conserved hypothetical protein 6.06 1 1 2 3 4.958E7 285.25 6.06 2 3 264 27.3 9.72 HVO_2810 succinate dehydrogenase subunit D 20.33 1 3 3 17 4.941E7 13.96 20.33 3 8 804.06 20.33 3 9 123 13.7 9.82 HVO_2813 RimK family protein 40.62 1 12 12 78 4.890E7 103.34 40.62 12 38 5441.63 40.62 12 40 453 49.0 4.73 HVO_1212 KaiC-type circadian regulator CirA 33.74 1 7 7 46 4.889E7 57.92 33.74 7 23 2980.64 33.74 7 23 246 27.5 4.45 HVO_0774 "probable glycosyltransferase, type 2" 44.33 1 8 8 50 4.843E7 68.20 44.33 8 25 3404.80 44.33 8 25 300 32.3 6.44 4504911 keratin 13 isoform b [Homo sapiens] 6.90 1 0 4 17 4.761E7 15.60 6.90 4 9 694.68 6.90 3 8 420 45.8 4.88 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 6.33 1 0 4 17 4.761E7 15.60 6.33 4 9 694.68 6.33 3 8 458 49.6 4.96 HVO_2519 conserved hypothetical protein 37.43 1 9 9 69 4.761E7 96.23 32.72 8 33 5426.72 37.43 9 36 382 40.7 4.35 HVO_0629 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 13.86 1 4 4 24 4.745E7 25.77 13.86 4 12 1450.05 13.86 4 12 339 36.7 8.40 HVO_2617 TrkA-C domain protein 22.83 1 7 7 33 4.724E7 41.86 22.83 7 17 1865.36 22.83 7 16 403 42.0 4.96 HVO_1552 ArsR family transcription regulator 52.91 1 6 6 33 4.715E7 46.61 43.69 5 16 2249.29 52.91 6 17 206 20.8 4.65 HVO_0118 50S ribosomal protein L20e 43.10 1 2 2 12 4.693E7 8.87 43.10 2 6 775.46 43.10 2 6 58 6.4 6.52 HVO_B0118 SMC-like protein Sph2 17.70 1 9 9 52 4.681E7 58.05 17.70 9 26 3443.61 17.70 9 26 644 73.8 4.41 HVO_0353 30S ribosomal protein S12 28.87 1 4 4 30 4.677E7 28.94 28.87 4 15 1568.34 28.87 4 15 142 15.5 9.91 HVO_1854 histidine--tRNA ligase 21.81 1 7 7 44 4.641E7 54.61 21.81 7 22 2867.08 21.81 7 22 431 47.1 4.37 HVO_1575 arginase 33.11 1 7 7 40 4.639E7 41.67 33.11 7 20 1625.35 33.11 7 20 299 31.0 4.58 HVO_0123 signal recognition particle 54K protein 20.22 1 7 7 30 4.636E7 13.21 18.06 6 13 1522.88 17.42 6 17 465 50.9 4.50 HVO_0048 argininosuccinate lyase 26.84 1 9 9 52 4.622E7 75.74 26.84 9 26 3693.37 26.84 9 26 488 50.8 4.53 HVO_0702 DUF2298 family protein 11.82 1 7 7 24 4.607E7 22.50 11.18 6 10 1394.17 11.82 7 14 787 82.8 6.04 HVO_0724 ArsA family ATPase 20.05 1 5 5 38 4.549E7 48.18 20.05 5 18 2333.30 20.05 5 20 409 43.9 4.22 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 16.49 1 6 6 26 4.548E7 24.06 16.49 6 13 1282.74 16.49 6 13 461 50.7 4.73 HVO_1394 probable NhaC-type sodium/proton antiporter 6.40 1 3 3 16 4.546E7 16.72 4.26 2 6 1416.35 6.40 3 10 516 53.0 4.84 HVO_B0045 diaminobutyrate decarboxylase 4.99 1 2 2 9 4.528E7 3.59 4.99 2 4 317.12 4.99 2 5 521 56.1 4.61 HVO_3001 ABC-type transport system permease protein 8.47 1 2 2 8 4.502E7 10.95 8.47 2 4 518.12 8.47 2 4 307 33.0 9.69 HVO_2195 sensor box histidine kinase (nonfunctional) 3.53 1 1 2 3 4.496E7 180.96 3.53 2 3 679 73.3 4.98 HVO_2945 valine--tRNA ligase 16.09 1 10 10 37 4.472E7 21.52 14.60 9 17 2148.02 12.41 9 20 870 98.9 4.36 HVO_1988 conserved hypothetical protein 13.18 1 2 2 10 4.448E7 19.74 13.18 2 5 865.45 13.18 2 5 349 35.2 4.25 HVO_0104 DNA repair and recombination protein RadA 16.91 1 4 4 13 4.418E7 12.27 9.04 2 4 1323.19 16.91 4 9 343 37.3 4.64 HVO_2033 ABC-type transport system permease protein (probable substrate sugar) 3.46 1 1 2 2 4.400E7 0.00 3.46 2 2 376 38.5 4.65 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 15.22 1 5 5 26 4.393E7 26.83 15.22 5 13 1429.59 15.22 5 13 427 45.4 4.56 HVO_1563 conserved hypothetical protein 27.20 1 3 3 12 4.378E7 15.57 27.20 3 6 974.83 27.20 3 6 125 13.8 11.02 HVO_1370 gamma-glutamyl phosphate reductase 28.15 1 7 7 34 4.364E7 19.19 28.15 7 17 1377.89 28.15 7 17 444 48.1 4.34 HVO_0122 phosphoglycerate dehydrogenase 31.79 1 6 6 34 4.347E7 38.95 19.14 4 14 2189.76 31.79 6 20 324 35.3 5.35 HVO_1148 30S ribosomal protein S15 47.10 1 4 4 26 4.345E7 36.58 47.10 4 13 1961.19 47.10 4 13 155 17.5 4.91 HVO_0842 cytochrome bc1 complex cytochrome b subunit 12.88 1 5 5 45 4.339E7 28.77 12.88 5 22 2002.63 12.88 5 23 264 30.5 6.89 HVO_A0576 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 11.72 1 3 3 6 4.333E7 6.10 11.72 3 3 300.19 11.72 3 3 435 45.5 4.17 HVO_0321 peptide chain release factor aRF-1 4.59 1 2 2 2 4.325E7 1.81 4.59 2 2 414 46.6 4.83 HVO_0788 tryptophan synthase beta subunit 15.64 1 5 5 20 4.304E7 25.74 15.64 5 10 1209.34 15.64 5 10 422 45.7 4.65 HVO_0704 "probable glycosyltransferase, type 2" 58.62 1 10 10 43 4.294E7 41.29 52.11 9 21 2237.40 58.62 10 22 261 28.4 5.30 HVO_B0132 PQQ repeat protein 44.20 1 8 8 49 4.293E7 54.40 44.20 8 24 2143.88 44.20 8 25 405 41.9 4.64 HVO_2533 conserved hypothetical protein 28.27 1 6 6 44 4.232E7 60.42 21.13 5 22 3150.80 28.27 6 22 336 35.1 4.39 HVO_B0371 aldehyde dehydrogenase 27.62 1 5 5 42 4.223E7 74.76 27.62 5 21 2863.95 27.62 5 21 496 52.5 4.39 HVO_2203 conserved hypothetical protein 28.41 1 3 3 44 4.208E7 42.65 28.41 3 23 1869.13 28.41 3 21 264 28.4 4.20 HVO_0285 probable metalloprotease 14.10 1 5 5 24 4.179E7 24.11 14.10 5 12 1539.99 14.10 5 12 390 42.1 4.98 HVO_1284 GTP cyclohydrolase III 18.77 1 4 4 24 4.168E7 28.13 18.77 4 12 1668.92 18.77 4 12 261 28.9 4.70 HVO_0958 conserved hypothetical protein 22.97 1 3 3 22 4.158E7 20.72 22.97 3 11 1093.05 22.97 3 11 148 15.5 10.26 HVO_1609 conserved hypothetical protein 14.48 1 3 3 22 4.098E7 27.99 14.48 3 10 1478.99 14.48 3 12 290 31.0 4.58 HVO_1175 DUF2110 family protein 13.78 1 2 2 8 4.089E7 8.43 13.78 2 4 555.99 13.78 2 4 225 24.4 4.63 HVO_2881 DUF4013 family protein 16.08 1 3 3 10 4.072E7 12.93 16.08 3 5 659.65 16.08 3 5 255 27.5 4.79 HVO_0020 ABC-type transport system ATP-binding protein (probable substrate thiamine) 28.81 1 5 5 26 4.051E7 38.73 28.81 5 13 1850.14 28.81 5 13 361 38.3 4.79 HVO_0203 replication factor C small subunit 29.36 1 8 8 119 4.015E7 133.82 29.36 8 60 7215.87 29.36 8 59 327 36.2 4.51 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 11.71 1 4 4 15 4.000E7 16.89 9.70 3 7 780.76 11.71 4 8 299 32.0 4.53 HVO_1023 conserved hypothetical protein 17.71 1 4 4 22 4.000E7 13.12 17.71 4 11 1170.03 17.71 4 11 271 30.2 4.63 HVO_B0194 conserved hypothetical protein 21.57 1 7 7 24 3.991E7 20.00 21.57 7 11 1382.49 21.57 7 13 394 42.7 5.35 HVO_2993 prepilin peptidase 31.43 1 9 9 36 3.979E7 37.36 31.43 9 19 2003.65 28.00 8 17 350 37.3 4.72 HVO_2187 CHP01210 family protein 26.39 1 6 6 35 3.924E7 31.47 17.22 5 17 1677.70 26.39 6 18 360 40.0 4.58 HVO_1481 UspA domain protein 34.97 1 4 4 22 3.906E7 19.80 34.97 4 11 948.55 34.97 4 11 163 17.7 4.40 HVO_0995 conserved hypothetical protein 5.80 1 2 2 10 3.904E7 7.08 5.80 2 5 474.88 5.80 2 5 345 35.9 4.96 HVO_1593 PAC2 family protein 35.08 1 5 5 30 3.883E7 46.39 35.08 5 15 1928.42 35.08 5 15 248 26.6 4.46 HVO_A0350 conserved hypothetical protein 26.76 1 5 5 13 3.883E7 10.58 21.13 4 6 690.77 26.76 5 7 213 23.8 9.64 HVO_B0135 conserved hypothetical protein 8.68 1 2 2 4 3.871E7 441.00 8.68 2 4 288 28.9 8.81 HVO_0850 proteasome-activating nucleotidase 47.65 1 11 11 89 3.871E7 92.37 42.47 10 44 4519.87 47.65 11 45 405 45.6 4.60 HVO_C0075 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 21.33 1 7 7 61 3.864E7 66.15 15.23 6 29 3285.46 21.33 7 32 558 61.3 4.56 HVO_2163 ABC-type transport system ATP-binding protein (homolog to LolDCE lipoprotein release factor) 38.55 1 7 7 40 3.858E7 61.58 38.55 7 20 2703.62 38.55 7 20 249 26.7 6.90 HVO_2123 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 21.23 1 5 6 26 3.858E7 23.03 21.23 6 14 958.21 21.23 6 12 358 38.8 4.61 HVO_2079 RND superfamily permease 12.53 1 6 6 30 3.842E7 33.55 12.53 6 15 1509.07 12.53 6 15 750 80.5 4.96 HVO_0590 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase 13.52 1 3 3 12 3.821E7 17.04 13.52 3 6 574.57 13.52 3 6 355 35.6 4.30 HVO_2172 conserved hypothetical protein 10.66 1 5 5 62 3.803E7 75.55 10.66 5 31 3530.67 10.66 5 31 741 75.2 4.27 HVO_2800 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 14.23 1 3 3 22 3.756E7 26.49 14.23 3 11 1473.53 14.23 3 11 253 27.6 4.42 HVO_0043 acetylornithine aminotransferase 15.61 1 4 4 26 3.756E7 36.60 15.61 4 13 1659.64 15.61 4 13 378 39.7 4.67 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 31.03 1 8 8 47 3.749E7 53.92 31.03 8 23 2521.91 31.03 8 24 348 38.2 4.32 HVO_2225 AstE family protein 34.31 1 6 6 36 3.743E7 40.12 34.31 6 19 1923.18 24.34 5 17 341 36.9 4.53 HVO_2062 DUF1628 family protein 37.93 1 2 2 398 3.729E7 522.31 37.93 2 206 16922.93 37.93 2 192 145 14.8 3.80 HVO_2607 PQQ repeat protein 22.91 1 6 7 34 3.728E7 30.56 21.67 6 16 1719.61 22.91 7 18 406 42.3 4.86 HVO_2413 translation elongation factor aEF-1 alpha subunit 36.67 1 7 10 93 3.668E7 84.29 36.67 10 45 4837.42 36.67 10 48 420 45.6 4.75 HVO_0417 metal-dependent carboxypeptidase 19.52 1 7 7 37 3.630E7 39.30 16.14 6 16 2098.03 19.52 7 21 502 57.3 4.42 HVO_2165 ABC-type transport system permease protein (homolog to LolDCE lipoprotein release factor) 20.05 1 6 6 22 3.614E7 22.54 20.05 6 11 1031.56 20.05 6 11 429 44.4 5.12 HVO_1164 HD family hydrolase 13.33 1 3 3 16 3.598E7 14.34 13.33 3 9 733.49 13.33 3 7 270 29.8 4.87 HVO_0055 CBS domain protein 41.20 1 8 8 30 3.589E7 33.74 41.20 8 15 1737.64 41.20 8 15 284 30.8 4.27 HVO_1572 DNA gyrase subunit B 26.29 1 12 12 59 3.588E7 66.70 26.29 12 31 2962.78 26.29 12 28 639 71.2 4.83 HVO_1979 tRNA pseudouridine synthase Pus10 6.32 1 2 2 8 3.580E7 8.40 6.32 2 4 482.56 6.32 2 4 427 46.9 4.39 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 25.00 1 8 8 36 3.529E7 53.95 25.00 8 18 2550.16 25.00 8 18 512 53.8 4.78 HVO_1038 uracil-DNA glycosylase superfamily protein 16.35 1 3 3 18 3.529E7 22.32 16.35 3 9 900.68 16.35 3 9 208 22.7 4.61 HVO_B0134 ABC-type transport system ATP-binding protein 28.68 1 4 4 22 3.514E7 23.42 28.68 4 11 845.87 28.68 4 11 258 27.2 4.53 HVO_2427 replication factor C large subunit 18.85 1 7 7 46 3.508E7 45.83 18.85 7 23 2602.12 18.85 7 23 488 53.4 4.67 HVO_2801 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 28.57 1 7 7 55 3.499E7 61.20 23.69 6 27 2819.43 28.57 7 28 287 31.4 4.48 HVO_0892 ABC-type transport system periplasmic substrate-binding protein (probable substrate copper) 15.76 1 8 8 33 3.491E7 32.45 15.76 8 16 1745.03 15.76 8 17 641 67.1 4.70 HVO_0564 ABC-type transport system periplasmic substrate-binding protein (probable substrate maltose) 16.90 1 4 4 19 3.472E7 27.52 16.90 4 10 1099.82 16.90 4 9 432 46.8 4.18 HVO_0600 ACT domain protein 17.51 1 2 2 14 3.447E7 21.72 17.51 2 7 1016.57 17.51 2 7 177 19.2 4.44 HVO_B0197 ABC-type transport system permease protein (probable substrate iron-III) 6.22 1 2 2 12 3.445E7 15.35 6.22 2 6 894.82 6.22 2 6 370 38.7 8.12 HVO_0185 twin arginine translocation system subunit TatCt 10.72 1 5 5 25 3.442E7 23.14 10.72 5 13 1194.55 10.72 5 12 718 77.9 4.94 HVO_0452 leucine--tRNA ligase 17.75 1 12 12 50 3.440E7 58.65 14.93 11 25 2957.34 17.75 12 25 958 109.5 4.37 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 37.23 1 4 4 38 3.428E7 47.83 37.23 4 19 2039.05 37.23 4 19 188 20.5 4.60 HVO_2418 conserved hypothetical protein 18.61 1 9 9 41 3.425E7 53.24 18.61 9 20 2560.73 18.61 9 21 892 94.6 4.16 HVO_1602 ABC-type transport system permease protein (probable substrate sulfonate) 10.73 1 4 4 22 3.419E7 24.10 10.73 4 11 1006.95 10.73 4 11 289 31.0 5.00 HVO_1654 cysteine synthase 22.88 1 5 5 16 3.416E7 14.45 22.88 5 8 834.73 22.88 5 8 306 32.3 4.32 HVO_2721 amidophosphoribosyltransferase 13.39 1 4 4 30 3.366E7 35.42 13.39 4 15 1582.83 13.39 4 15 493 53.4 4.78 HVO_1057 Trk potassium uptake system protein TrkH 4.68 1 3 3 7 3.365E7 5.61 3.56 2 3 374.28 4.68 3 4 534 57.3 6.37 HVO_1868 conserved hypothetical protein 29.05 1 4 4 24 3.342E7 33.99 29.05 4 12 1595.58 29.05 4 12 179 20.0 5.38 HVO_1125 cysteine--tRNA ligase 38.26 1 11 12 65 3.332E7 87.82 38.26 12 33 4001.30 37.45 11 32 494 55.2 4.56 HVO_2047 conserved hypothetical protein 33.45 1 7 7 55 3.314E7 57.78 33.45 7 26 3352.12 33.45 7 29 296 34.2 4.93 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 25.90 1 5 5 26 3.306E7 39.83 25.90 5 13 1911.55 25.90 5 13 305 32.7 4.56 HVO_1443 ABC-type transport system ATP-binding protein 20.91 1 5 5 28 3.300E7 27.26 20.91 5 14 1900.50 20.91 5 14 330 36.3 4.70 HVO_B0037 ABC-type transport system ATP-binding protein (probable substrate sugar) 16.71 1 1 3 17 3.297E7 24.32 5.48 2 7 1608.27 16.71 3 10 383 42.7 4.45 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 11.46 1 2 3 16 3.296E7 23.31 10.03 2 8 1211.92 11.46 3 8 349 37.0 4.70 HVO_2356 GNAT family acetyltransferase 18.92 1 5 5 28 3.295E7 37.99 18.92 5 14 1785.97 18.92 5 14 407 45.1 4.64 HVO_C0074 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 24.78 1 12 12 54 3.259E7 52.47 24.78 12 27 2844.65 24.78 12 27 690 75.9 4.79 HVO_0162 peptidase M48 family protein 10.66 1 3 3 14 3.257E7 18.37 10.66 3 7 759.50 10.66 3 7 366 39.0 9.39 HVO_0046 putative glutamate--argW ligase 20.27 1 5 5 26 3.255E7 22.17 20.27 5 13 1343.70 20.27 5 13 291 31.9 4.87 HVO_2481 HD family hydrolase 40.51 1 8 8 39 3.237E7 33.51 33.59 7 19 1668.44 40.51 8 20 390 42.7 6.14 HVO_0100 NMD3 family protein 6.40 1 2 2 2 3.217E7 4.70 6.40 2 2 375 41.6 4.46 HVO_2998 homoserine O-acetyltransferase 33.98 1 8 8 33 3.212E7 29.12 33.98 8 17 1486.26 31.57 7 16 415 44.8 4.69 HVO_0060 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 12.11 1 4 4 44 3.210E7 64.12 12.11 4 22 3162.91 12.11 4 22 479 51.5 5.11 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 40.18 1 4 4 14 3.146E7 10.67 40.18 4 7 526.42 40.18 4 7 219 22.4 4.06 HVO_0022 ABC-type transport system periplasmic substrate-binding protein (probable substrate thiamine) 23.28 1 5 5 18 3.094E7 22.51 23.28 5 9 941.12 23.28 5 9 378 41.1 4.20 HVO_1523 agl cluster protein AglQ 29.92 1 6 6 52 3.090E7 47.69 29.92 6 26 2471.28 29.92 6 26 371 42.1 6.04 HVO_B0354 conserved hypothetical protein 13.95 1 8 8 38 3.081E7 39.49 13.95 8 19 1972.11 12.26 7 19 767 85.4 4.68 HVO_2716 acyl-CoA dehydrogenase 23.88 1 6 6 30 3.054E7 27.60 23.88 6 15 1345.14 23.88 6 15 381 41.3 4.65 HVO_2267 hypothetical protein 21.04 1 7 7 35 3.038E7 46.41 21.04 7 17 1883.75 21.04 7 18 385 44.3 4.56 HVO_1847 oligoendopeptidase PepF 17.36 1 6 6 27 3.037E7 30.32 13.69 5 12 1537.60 17.36 6 15 599 68.5 4.41 HVO_0466 citrate (si)-synthase 20.84 1 5 5 19 3.033E7 26.74 20.84 5 9 1114.51 20.84 5 10 379 41.8 4.55 HVO_2055 probable transport protein (probable polysaccharide biosynthesis transport protein) 8.90 1 3 3 9 3.017E7 12.12 8.90 3 5 665.67 6.57 2 4 472 51.1 9.11 HVO_1327 AAA-type ATPase (CDC48 subfamily) 29.76 1 11 12 40 3.004E7 50.60 27.17 11 20 2330.45 26.77 11 20 736 78.1 4.88 HVO_0467 PhoU/TrkA-C domain protein 30.10 1 9 9 44 3.000E7 55.32 30.10 9 22 2609.52 30.10 9 22 402 43.3 4.49 HVO_0739 conserved hypothetical protein 14.59 1 3 3 10 2.990E7 7.00 14.59 3 5 458.35 14.59 3 5 329 33.5 4.97 HVO_2496 adenylate kinase 13.46 1 2 2 16 2.960E7 16.28 13.46 2 8 993.40 13.46 2 8 208 23.1 4.25 HVO_1242 conserved hypothetical protein 18.98 1 7 7 18 2.952E7 16.25 18.98 7 10 809.59 14.58 5 8 432 47.1 4.75 HVO_B0295 ABC-type transport system ATP-binding protein (probable substrate glycerol-3-phosphate) 8.75 1 2 3 15 2.952E7 29.21 8.75 3 8 1185.93 8.75 3 7 377 41.2 4.74 HVO_1048 phosphoribosylformylglycinamidine synthase 2 28.35 1 11 11 56 2.952E7 79.35 27.35 10 27 3543.99 28.35 11 29 702 72.9 4.18 HVO_0233 ribose-phosphate pyrophosphokinase 33.57 1 5 5 39 2.951E7 43.42 33.57 5 20 1989.20 33.57 5 19 283 29.6 4.40 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 19.37 1 3 3 10 2.950E7 6.28 19.37 3 5 583.83 15.42 2 5 253 26.0 4.60 HVO_2648 phosphoglycerate dehydrogenase 8.15 1 2 2 8 2.950E7 8.97 8.15 2 4 649.86 8.15 2 4 319 34.2 4.64 HVO_B0082 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 17.05 1 5 5 34 2.949E7 43.34 17.05 5 17 2265.10 17.05 5 17 569 62.8 4.30 HVO_1625 conserved hypothetical protein 14.07 1 6 7 30 2.930E7 35.29 14.07 7 15 1862.51 14.07 7 15 654 70.1 4.04 HVO_2643 NADPH:quinone reductase 30.06 1 6 6 35 2.921E7 29.19 30.06 6 18 1831.64 25.72 5 17 346 37.2 4.55 HVO_1134 conserved hypothetical protein 19.02 1 9 9 28 2.920E7 28.59 19.02 9 14 1465.15 19.02 9 14 757 80.6 4.35 HVO_2040 NAD-dependent epimerase/dehydratase 29.41 1 3 7 55 2.916E7 48.04 29.41 7 28 2591.77 29.41 7 27 306 33.8 4.51 HVO_0309 S-adenosylmethionine-dependent methyltransferase 21.74 1 4 4 20 2.912E7 21.29 21.74 4 10 900.13 21.74 4 10 207 23.7 4.97 HVO_2602 transport protein (probable substrate zinc/cadmium) 18.01 1 4 4 19 2.907E7 22.36 13.83 3 9 1080.99 18.01 4 10 311 33.3 4.77 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 15.92 1 4 4 14 2.888E7 6.68 15.92 4 7 678.05 15.92 4 7 333 36.7 4.56 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 22.12 1 5 5 20 2.884E7 15.48 22.12 5 10 952.27 19.03 4 10 226 25.5 4.25 HVO_1079 sulfate adenylyltransferase small subunit 9.23 1 2 2 9 2.873E7 10.23 9.23 2 5 432.52 9.23 2 4 325 37.5 4.18 HVO_2348 GTP cyclohydrolase MptA 25.32 1 5 5 13 2.859E7 8.86 16.23 4 6 611.27 25.32 5 7 308 33.5 4.68 HVO_A0087 fumarylacetoacetase family protein 13.49 1 2 2 8 2.856E7 7.86 13.49 2 4 434.47 13.49 2 4 289 32.0 4.21 HVO_2066 conserved hypothetical protein 14.18 1 3 3 25 2.846E7 23.29 14.18 3 13 987.95 14.18 3 12 402 42.0 4.54 HVO_2340 amine oxidase family protein 23.34 1 4 4 17 2.836E7 14.46 23.34 4 9 697.75 15.79 3 8 437 48.7 4.44 HVO_2001 tRNA-guanine(15) transglycosylase 16.86 1 4 4 25 2.825E7 22.91 16.86 4 12 1328.10 16.86 4 13 516 56.3 4.59 HVO_2057 sugar nucleotidyltransferase 16.81 1 4 4 22 2.823E7 29.39 16.81 4 11 1271.42 16.81 4 11 357 37.8 4.44 HVO_B0111 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 30.17 1 9 9 67 2.821E7 68.33 30.17 9 33 3170.32 30.17 9 34 401 44.2 4.54 HVO_1660 DisA-N domain protein 18.59 1 4 4 16 2.809E7 21.73 18.59 4 8 1288.21 18.59 4 8 269 28.9 4.73 HVO_2711 DoxX domain protein 14.86 1 5 5 24 2.799E7 16.68 14.86 5 12 1216.54 14.86 5 12 370 38.1 7.06 HVO_2173 DUF1616 family protein 23.65 1 7 7 40 2.795E7 36.25 23.65 7 20 1781.62 23.65 7 20 334 36.6 4.92 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 24.92 1 8 9 27 2.778E7 8.89 23.00 8 14 821.05 20.61 8 13 626 67.6 4.65 HVO_1859 UPF0104 family protein 4.39 1 1 2 8 2.763E7 0.00 4.39 2 4 218.16 4.39 2 4 342 36.0 9.38 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 21.24 1 4 4 14 2.753E7 20.90 21.24 4 7 1323.81 21.24 4 7 259 28.0 4.50 HVO_1198 UspA domain protein 24.14 1 3 3 11 2.724E7 8.52 24.14 3 6 424.78 24.14 3 5 145 15.6 4.75 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 29.37 1 6 6 32 2.701E7 37.86 29.37 6 16 1860.58 29.37 6 16 286 31.2 4.54 HVO_2059 NAD-dependent epimerase/dehydratase 19.35 1 5 5 20 2.692E7 9.73 16.77 4 9 1058.06 19.35 5 11 310 34.1 4.40 HVO_A0550 receiver/sensor box histidine kinase 4.18 1 2 3 4 2.689E7 1.98 4.18 3 4 885 95.9 4.46 HVO_1112 ABC-type transport system ATP-binding protein (probable substrate cobalamin) 7.56 1 2 2 14 2.686E7 23.06 7.56 2 7 1117.70 7.56 2 7 476 49.4 4.55 HVO_2590 probable oxidoreductase (short-chain dehydrogenase family) 15.43 1 3 3 13 2.680E7 6.48 15.43 3 6 439.49 15.43 3 7 311 33.6 4.89 HVO_1262 probable NhaC-type sodium/proton antiporter 7.84 1 2 2 12 2.671E7 17.36 7.84 2 6 756.08 7.84 2 6 485 49.9 4.68 HVO_1558 cytochrome P450 21.43 1 8 9 28 2.668E7 25.40 19.59 8 14 1351.47 20.51 8 14 434 48.4 4.92 HVO_2921 conserved hypothetical protein 15.36 1 4 4 17 2.644E7 19.77 10.78 3 8 965.55 15.36 4 9 306 32.7 4.34 HVO_1657 phosphoribosylamine--glycine ligase 12.15 1 5 5 18 2.638E7 13.34 9.35 4 8 926.16 12.15 5 10 428 45.5 4.20 HVO_1371 glutamate 5-kinase 9.30 1 2 3 11 2.626E7 11.09 9.30 3 6 620.90 9.30 3 5 301 32.0 4.25 HVO_A0380 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 11.37 1 5 5 26 2.621E7 25.70 11.37 5 13 1149.51 11.37 5 13 563 62.8 4.70 HVO_0469 AstE family protein 32.08 1 7 7 26 2.618E7 36.74 32.08 7 13 1727.27 32.08 7 13 318 33.9 5.85 HVO_1398 ABC-type transport system permease protein (probable substrate sugar) 10.08 1 3 3 16 2.616E7 18.00 10.08 3 8 1138.88 10.08 3 8 367 38.4 6.57 HVO_1123 thioredoxin-disulfide reductase 8.60 1 2 2 3 2.613E7 278.51 8.60 2 3 349 37.3 4.32 HVO_0175 DNA polymerase sliding clamp 14.57 1 3 3 28 2.607E7 20.74 14.57 3 14 1524.89 14.57 3 14 247 26.7 4.39 HVO_0681 DNA topoisomerase I 11.67 1 8 8 32 2.586E7 30.43 11.67 8 16 1653.73 11.67 8 16 840 93.6 4.58 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 16.22 1 4 4 15 2.586E7 15.59 16.22 4 8 683.40 8.23 3 7 413 45.8 4.45 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 15.72 1 8 9 30 2.578E7 27.90 15.44 8 14 1658.59 15.72 9 16 706 73.3 4.39 HVO_2167 conserved hypothetical protein 18.81 1 3 3 22 2.572E7 11.71 18.81 3 11 923.39 18.81 3 11 303 31.8 5.12 HVO_1058 TrkA domain protein 6.07 1 2 2 8 2.566E7 9.77 6.07 2 4 536.90 6.07 2 4 445 47.7 4.35 HVO_1545 dihydroxyacetone kinase subunit DhaL 41.81 1 7 8 32 2.565E7 29.97 41.81 8 16 1713.64 41.81 8 16 232 24.8 4.48 HVO_1579 uridine phosphorylase 23.90 1 4 4 13 2.545E7 11.61 22.43 3 6 591.97 23.90 4 7 272 29.0 4.64 HVO_1240 conserved hypothetical protein 20.11 1 5 5 25 2.545E7 11.43 20.11 5 13 967.39 20.11 5 12 353 37.4 4.49 HVO_0573 endonuclease IV 15.12 1 2 2 15 2.525E7 7.98 15.12 2 7 518.62 15.12 2 8 291 31.4 4.44 HVO_2530 homolog to phosphoribosylamine--glycine ligase 13.41 1 4 4 10 2.525E7 5.84 7.05 3 4 373.53 13.41 4 6 440 49.8 4.70 HVO_1289 OsmC domain protein 18.94 1 2 2 5 2.512E7 5.78 18.94 2 3 242.65 18.94 2 2 132 14.2 3.85 HVO_2736 tRNA(Met) cytidine acetyltransferase 4.51 1 3 3 10 2.509E7 8.30 4.51 3 5 528.24 4.51 3 5 754 81.2 4.96 HVO_1568 alpha/beta hydrolase fold protein 31.77 1 5 5 28 2.506E7 33.49 31.77 5 14 1597.93 31.77 5 14 277 29.4 4.94 HVO_1456 receiver/sensor box histidine kinase 2.17 1 0 2 2 2.493E7 0.00 2.17 2 2 506 53.8 4.70 HVO_B0144 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 17.46 1 3 3 16 2.491E7 8.60 17.46 3 8 747.45 17.46 3 8 401 44.3 4.40 HVO_0177 arsenate reductase (glutaredoxin) 18.30 1 2 2 4 2.491E7 0.00 18.30 2 2 46.18 18.30 2 2 153 16.6 4.31 HVO_1477 endonuclease domain protein 14.37 1 2 3 11 2.467E7 15.26 13.15 2 5 447.68 14.37 3 6 327 34.1 4.32 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 12.56 1 4 4 15 2.465E7 22.54 10.73 3 7 1080.48 12.56 4 8 438 46.4 4.58 HVO_2125 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 8.15 1 2 2 8 2.436E7 13.60 8.15 2 4 560.21 8.15 2 4 319 34.9 8.92 HVO_2228 PHP domain protein 15.22 1 4 4 12 2.424E7 10.94 15.22 4 6 799.92 15.22 4 6 289 31.2 9.82 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 10 2.414E7 11.15 11.64 2 5 848.28 11.64 2 5 189 20.3 4.22 HVO_2981 uracil phosphoribosyltransferase 34.51 1 5 5 17 2.400E7 13.25 26.99 4 7 920.66 34.51 5 10 226 24.5 4.49 HVO_0480 phosphoglycerate kinase 19.45 1 6 6 24 2.390E7 32.92 19.45 6 12 1501.67 19.45 6 12 401 43.6 4.37 HVO_0109 cysteine desulfurase 18.31 1 5 5 20 2.389E7 18.24 18.31 5 10 993.32 18.31 5 10 426 46.8 4.56 HVO_B0182 deoxyhypusine synthase 7.72 1 2 2 8 2.362E7 4.46 7.72 2 4 318.40 7.72 2 4 324 35.6 4.30 HVO_1354 DNA mismatch repair protein MutS 12.59 1 7 7 25 2.361E7 22.91 12.59 7 12 1122.15 12.59 7 13 580 62.1 4.56 HVO_0462 cytochrome bd ubiquinol oxidase subunit I 11.39 1 4 4 16 2.361E7 16.41 11.39 4 8 844.91 11.39 4 8 474 52.1 4.77 HVO_2342 MATE efflux family protein 8.70 1 2 2 8 2.359E7 11.65 8.70 2 4 383.95 8.70 2 4 494 51.8 5.47 HVO_0154 conserved hypothetical protein 24.83 1 3 3 12 2.359E7 17.71 24.83 3 6 797.87 24.83 3 6 149 15.8 4.31 HVO_1649 methionine adenosyltransferase 32.09 1 6 6 22 2.354E7 21.79 32.09 6 11 1154.84 32.09 6 11 402 43.5 4.45 HVO_0402 DUF124 family protein 25.33 1 4 4 16 2.318E7 19.93 25.33 4 8 869.52 25.33 4 8 225 24.0 4.58 HVO_A0432 conserved hypothetical protein 18.52 1 0 5 29 2.306E7 24.14 18.52 5 15 1469.26 18.52 5 14 405 44.5 5.24 HVO_A0406 conserved hypothetical protein 24.20 1 1 6 30 2.306E7 24.14 18.52 5 15 1488.37 24.20 6 15 405 44.4 5.30 HVO_1399 ABC-type transport system permease protein (probable substrate sugar) 12.32 1 4 4 25 2.301E7 37.38 12.32 4 12 1819.71 12.32 4 13 422 43.8 4.64 HVO_0697 PAC2 family protein 25.49 1 3 3 10 2.295E7 18.19 25.49 3 5 804.11 25.49 3 5 255 27.4 4.08 HVO_B0154 receiver/sensor box histidine kinase 10.99 1 10 10 42 2.287E7 43.82 10.99 10 20 2176.58 10.99 10 22 1301 144.1 4.39 27894337 keratin 20 [Homo sapiens] 6.60 1 1 3 12 2.287E7 10.99 2.59 2 6 462.19 6.60 2 6 424 48.5 5.69 HVO_A0496 UspA domain protein 25.86 1 6 6 25 2.274E7 19.21 25.86 6 12 1005.34 25.86 6 13 290 31.4 4.60 HVO_0795 transcription initiation factor TFB 21.19 1 3 5 22 2.271E7 27.87 21.19 5 11 1500.21 21.19 5 11 335 37.4 5.59 HVO_1172 NAD-dependent epimerase/dehydratase 15.87 1 4 4 10 2.264E7 12.62 15.87 4 5 650.26 15.87 4 5 315 34.9 4.34 HVO_1690 DHH family phosphoesterase 20.21 1 7 7 24 2.259E7 17.45 20.21 7 12 1217.88 20.21 7 12 485 52.1 4.48 HVO_1495 "phosphotransferase system component IIB, fructose-specific" 13.29 1 2 2 12 2.258E7 17.62 13.29 2 6 715.35 13.29 2 6 158 16.3 4.46 HVO_A0045 HtpX-like protease 7.80 1 2 2 11 2.240E7 13.10 7.80 2 6 375.77 7.80 2 5 295 32.6 9.39 HVO_B0029 xylose dehydrogenase (NADP) 18.15 1 4 4 22 2.240E7 28.35 18.15 4 11 1265.41 18.15 4 11 325 34.7 4.39 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 22.40 1 6 7 24 2.234E7 30.33 21.49 6 12 1347.67 17.87 6 12 442 46.9 4.58 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 13.65 1 3 3 12 2.231E7 19.62 13.65 3 6 751.27 13.65 3 6 403 41.1 4.73 HVO_B0151 NikR family transcription regulator 20.42 1 1 2 3 2.224E7 135.52 20.42 2 3 142 16.1 4.74 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 19.31 1 4 4 46 2.213E7 27.85 15.44 3 21 2547.62 19.31 4 25 259 29.9 4.36 HVO_0953 conserved hypothetical protein 15.69 1 9 9 59 2.213E7 49.31 15.69 9 29 2936.31 15.69 9 30 612 65.9 4.64 HVO_A0088 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 2.83 1 2 4 13 2.201E7 5.16 2.83 4 7 471.36 2.83 4 6 1024 111.3 4.69 HVO_2164 ABC-type transport system permease protein (homolog to LolDCE lipoprotein release factor) 7.30 1 3 3 9 2.196E7 11.27 7.30 3 5 617.91 5.11 2 4 411 42.1 4.72 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 11.76 1 3 3 14 2.196E7 14.01 11.76 3 7 776.53 11.76 3 7 357 39.8 4.41 HVO_0324 arginine--tRNA ligase 13.97 1 6 6 20 2.186E7 22.27 13.97 6 10 920.74 13.97 6 10 587 65.0 4.35 HVO_1137 ion channel pore / TrkA domain protein 24.28 1 8 8 34 2.176E7 36.19 24.28 8 17 1543.05 24.28 8 17 552 58.7 4.56 HVO_2726 glutamate--tRNA ligase 17.26 1 7 7 26 2.172E7 20.71 15.56 6 13 1210.33 17.26 7 13 585 65.2 4.58 HVO_1594 tRNA/rRNA cytosine-C5-methylase 20.13 1 3 3 15 2.164E7 20.49 20.13 3 8 900.75 9.27 2 7 313 34.6 4.69 HVO_1693 conserved hypothetical protein 25.75 1 2 2 8 2.164E7 9.85 25.75 2 5 367.31 25.75 2 3 167 17.3 4.35 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 20.00 1 4 4 23 2.157E7 23.63 9.72 3 11 1268.32 20.00 4 12 360 39.5 4.31 HVO_B0142 ARM/HEAT repeat protein 10.76 1 2 2 4 2.155E7 4.18 10.76 2 2 102.01 10.76 2 2 344 36.1 4.65 HVO_0243 threonine aldolase 26.98 1 6 6 99 2.144E7 104.26 26.98 6 49 6972.57 26.98 6 50 341 35.6 4.55 HVO_0433 F420H2:NADP oxidoreductase 34.23 1 4 4 15 2.140E7 16.10 28.83 3 7 735.40 34.23 4 8 222 23.3 4.72 HVO_A0466 conserved hypothetical protein 15.82 1 4 4 18 2.139E7 19.90 15.82 4 9 678.13 15.82 4 9 550 58.2 4.53 HVO_1601 ABC-type transport system ATP-binding protein (probable substrate sulfonate) 25.09 1 5 5 30 2.100E7 42.60 25.09 5 15 1620.42 25.09 5 15 271 29.0 4.36 HVO_2381 UPF0272 family protein 6.29 1 2 2 18 2.098E7 28.55 6.29 2 9 1264.97 6.29 2 9 493 52.3 4.88 HVO_2241 conserved hypothetical protein 38.03 1 2 2 15 2.064E7 4.03 38.03 2 7 723.76 38.03 2 8 71 7.4 4.96 HVO_1055 TrkA domain protein 30.09 1 5 5 26 2.025E7 23.73 30.09 5 14 1401.98 20.80 4 12 226 24.4 4.39 HVO_0639 AAA-type ATPase (MoxR subfamily) 16.14 1 3 3 15 2.024E7 15.27 16.14 3 7 895.81 16.14 3 8 316 34.7 4.89 HVO_0173 DNA primase large subunit 5.74 1 1 2 3 2.014E7 0.00 5.74 2 3 366 40.0 4.60 HVO_2351 FxsA domain protein 7.22 1 3 3 9 2.009E7 1.81 5.15 2 4 269.54 7.22 3 5 194 20.1 5.29 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 13.72 1 2 2 4 2.003E7 9.68 13.72 2 4 430 44.2 4.37 HVO_A0557 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 13.97 1 2 2 2 1.999E7 32.86 13.97 2 2 408 44.2 4.31 HVO_2171 DUF58 family protein 8.00 1 3 3 18 1.993E7 24.85 8.00 3 9 892.31 8.00 3 9 475 50.8 4.93 HVO_1261 conserved hypothetical protein 13.55 1 6 6 19 1.981E7 16.02 13.55 6 10 795.45 10.87 5 9 598 62.6 4.64 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 21.82 1 5 5 19 1.980E7 22.17 18.78 4 9 1149.68 21.82 5 10 362 39.6 4.82 HVO_1685 conserved hypothetical protein 14.63 1 6 6 26 1.969E7 24.09 14.63 6 13 1490.15 14.63 6 13 492 54.5 5.74 HVO_2411 Mrp-type sodium/proton antiporter system subunit D2 5.06 1 2 2 4 1.966E7 5.89 5.06 2 2 189.51 5.06 2 2 494 51.0 7.94 HVO_1263 conserved hypothetical protein 12.63 1 2 2 3 1.958E7 5.74 12.63 2 3 198 21.0 4.88 HVO_2740 nucleoside-diphosphate kinase 29.87 1 4 4 33 1.955E7 43.17 29.87 4 19 2233.45 29.87 4 14 154 17.5 4.50 HVO_2670 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 6.81 1 6 6 18 1.955E7 9.39 6.81 6 9 718.38 6.81 6 9 1058 113.8 4.69 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 24.20 1 6 6 29 1.951E7 34.98 24.20 6 14 1855.03 24.20 6 15 343 38.4 4.94 HVO_0041 ornithine carbamoyltransferase 29.77 1 5 5 25 1.942E7 17.65 29.77 5 13 1131.55 27.09 4 12 299 32.7 4.37 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 15.13 1 4 4 19 1.921E7 26.35 11.58 3 9 1066.47 15.13 4 10 423 43.9 4.31 HVO_0655 NAD-dependent epimerase/dehydratase 19.35 1 6 6 24 1.919E7 20.16 19.35 6 12 1367.97 19.35 6 12 341 36.9 4.74 HVO_0694 probable phosphoribosyltransferase 21.52 1 3 3 7 1.912E7 4.76 10.13 2 2 311.60 21.52 3 5 237 27.0 4.32 HVO_A0553 adenosylcobyric acid synthase 22.46 1 6 6 26 1.899E7 23.90 22.46 6 13 1075.88 22.46 6 13 512 52.6 4.50 HVO_1340 "probable glycosyltransferase, type 1" 11.73 1 2 4 17 1.895E7 12.23 10.67 3 8 630.18 11.73 4 9 375 41.0 4.42 HVO_0913 MATE efflux family protein 9.58 1 4 4 14 1.876E7 6.65 9.58 4 7 555.60 9.58 4 7 480 49.7 5.16 HVO_A0429 homolog to D-aminoacylase 5.40 1 2 2 2 1.870E7 0.00 5.40 2 2 537 58.8 4.75 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 22.29 1 5 5 23 1.866E7 28.68 22.29 5 12 1361.91 22.29 5 11 323 34.9 5.24 HVO_1097 diaminopimelate epimerase 12.85 1 2 2 2 1.864E7 3.00 12.85 2 2 288 29.9 4.48 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 13.16 1 4 4 18 1.863E7 12.55 9.62 3 8 855.13 13.16 4 10 395 42.4 4.54 HVO_A0097 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 14.77 1 7 7 34 1.860E7 33.23 14.77 7 17 1709.97 14.77 7 17 650 70.2 4.27 HVO_2689 conserved hypothetical protein 9.85 1 2 2 6 1.856E7 8.38 9.85 2 3 405.02 9.85 2 3 264 27.6 4.20 HVO_0148 urease alpha subunit 11.44 1 3 3 16 1.848E7 29.53 11.44 3 8 1357.98 11.44 3 8 568 60.3 4.54 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 20.00 1 3 4 16 1.847E7 11.68 20.00 4 8 603.60 20.00 4 8 265 28.7 4.87 HVO_2745 mechanosensitive channel protein MscS 25.94 1 4 4 21 1.844E7 30.66 20.91 3 10 1197.12 25.94 4 11 397 42.7 4.93 HVO_2286 conserved hypothetical protein 30.41 1 7 7 32 1.839E7 38.37 24.15 6 15 1854.55 30.41 7 17 559 62.3 4.35 HVO_2961 dihydrolipoyl dehydrogenase 25.05 1 7 7 38 1.837E7 41.13 25.05 7 18 1855.12 25.05 7 20 475 49.9 4.41 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 14.29 1 5 5 13 1.836E7 13.35 14.29 5 7 659.62 11.67 4 6 420 45.0 4.86 HVO_0519 replication protein A 21.12 1 8 8 36 1.834E7 37.31 21.12 8 18 1899.81 21.12 8 18 483 51.0 4.13 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 21.10 1 6 6 23 1.820E7 16.81 15.40 5 11 1048.47 21.10 6 12 526 57.2 4.31 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 7.51 1 3 3 16 1.812E7 14.71 7.51 3 8 674.50 7.51 3 8 373 40.2 4.44 HVO_1577 conserved hypothetical protein 44.07 1 5 5 22 1.801E7 29.60 44.07 5 12 1206.07 23.73 4 10 177 19.4 4.74 HVO_2156 UspA domain protein 16.94 1 3 3 16 1.796E7 18.09 16.94 3 8 1070.66 16.94 3 8 301 31.6 4.69 HVO_2958 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit 16.85 1 4 4 12 1.789E7 11.57 16.85 4 6 707.52 16.85 4 6 368 40.9 4.68 HVO_1260 von Willebrand factor type A domain protein 16.26 1 6 7 18 1.786E7 19.64 16.26 7 10 1019.87 9.66 5 8 818 85.1 4.65 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 6.23 1 2 2 6 1.780E7 8.31 6.23 2 3 234.09 6.23 2 3 337 35.9 4.39 HVO_2419 hydroxymethylglutaryl-CoA synthase 4.49 1 2 2 8 1.773E7 3.83 4.49 2 4 363.41 4.49 2 4 445 50.1 4.64 HVO_1658 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 21.67 1 2 2 22 1.762E7 28.60 21.67 2 11 1203.64 21.67 2 11 180 19.6 5.24 HVO_2790 ATP-binding protein Mrp 21.39 1 4 4 18 1.755E7 26.59 21.39 4 9 1123.65 21.39 4 9 346 36.8 4.50 HVO_B0117 conserved hypothetical protein 18.27 1 3 3 8 1.752E7 8.91 18.27 3 4 585.47 18.27 3 4 208 23.3 4.58 HVO_2675 histidinol dehydrogenase 33.88 1 7 7 29 1.751E7 22.36 33.88 7 14 1404.56 28.97 6 15 428 45.4 4.50 HVO_1675 magnesium transport protein CorA 13.76 1 4 4 15 1.751E7 13.71 13.76 4 7 1041.34 13.76 4 8 327 37.2 4.55 HVO_2616 ion channel pore / TrkA domain protein 6.70 1 2 2 8 1.749E7 10.16 6.70 2 4 485.53 6.70 2 4 403 42.7 4.84 HVO_1160 type IV pilus biogenesis complex ATPase subunit 3.73 1 1 2 3 1.743E7 0.00 3.73 2 3 1100 120.4 4.37 HVO_0120 signal recognition particle receptor FtsY 24.56 1 6 6 24 1.738E7 27.42 24.56 6 12 1042.26 24.56 6 12 456 48.2 4.17 HVO_C0069 GFO family oxidoreductase 29.63 1 6 6 30 1.736E7 26.22 29.63 6 15 1211.84 29.63 6 15 324 36.0 5.10 HVO_A0606 major facilitator superfamily transporter 1.83 1 0 2 4 1.730E7 0.00 1.83 2 4 437 46.7 8.28 HVO_1129 conserved hypothetical protein 13.85 1 3 3 12 1.715E7 12.44 13.85 3 6 606.44 13.85 3 6 390 43.0 4.44 HVO_0588 cobalamin (5'-phosphate) synthase 12.20 1 2 2 8 1.695E7 11.94 12.20 2 4 569.25 12.20 2 4 254 24.8 6.90 HVO_0637 DUF11/DUF58 family protein 9.48 1 3 3 11 1.694E7 13.16 9.48 3 6 567.26 7.11 2 5 422 45.1 5.17 HVO_2637 conserved hypothetical protein 8.47 1 2 2 6 1.692E7 5.21 8.47 2 3 312.04 8.47 2 3 366 39.1 4.81 HVO_1576 NAD-dependent epimerase/dehydratase 20.59 1 1 5 25 1.686E7 14.40 20.59 5 13 989.57 20.59 5 12 306 33.9 4.51 HVO_2075 IS1341-type transposase 2.88 1 1 2 3 1.680E7 0.00 2.88 2 3 416 47.1 6.48 HVO_0959 conserved hypothetical protein 20.18 1 3 3 12 1.679E7 8.80 20.18 3 6 619.98 20.18 3 6 228 25.7 4.84 HVO_2183 aldehyde ferredoxin oxidoreductase 3.27 1 2 2 2 1.658E7 1.61 3.27 2 2 643 69.3 4.59 HVO_2630 conserved hypothetical protein 33.44 1 6 6 20 1.641E7 10.99 33.44 6 10 928.95 33.44 6 10 302 32.9 4.48 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 9.92 1 2 2 16 1.625E7 24.42 9.92 2 8 845.00 9.92 2 8 383 42.0 4.49 HVO_B0365 dimethylsulfoxide reductase subunit C 8.24 1 3 3 9 1.611E7 10.70 8.24 3 5 387.76 5.26 2 4 437 47.3 6.81 HVO_0583 conserved hypothetical protein 26.80 1 3 3 22 1.609E7 37.36 26.80 3 11 1636.42 26.80 3 11 194 21.2 4.42 HVO_0933 P-type transport ATPase (probable substrate copper/metal cation) 7.21 1 5 5 18 1.603E7 16.30 7.21 5 10 879.14 4.14 3 8 943 99.2 4.55 HVO_2524 phytoene synthase 32.74 1 6 6 16 1.599E7 7.03 23.30 5 7 609.59 32.74 6 9 339 38.3 4.82 HVO_2084 ABC-type transport system permease protein (probable substrate macrolides) 10.79 1 4 4 14 1.590E7 12.73 8.68 3 6 886.22 10.79 4 8 380 39.9 4.48 HVO_A0156 acyl-CoA synthetase 7.83 1 1 3 12 1.586E7 14.21 7.83 3 6 578.67 7.83 3 6 664 74.0 4.40 HVO_0396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 14.44 1 4 4 12 1.581E7 15.74 14.44 4 6 643.17 14.44 4 6 360 39.2 5.01 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 7.44 1 2 2 10 1.565E7 13.20 7.44 2 5 678.48 7.44 2 5 430 45.1 4.50 HVO_1374 acyl-CoA synthetase 4.70 1 2 2 8 1.565E7 11.45 4.70 2 4 567.76 4.70 2 4 553 61.1 4.50 HVO_B0101 IclR family transcription regulator 26.46 1 5 5 28 1.543E7 35.09 26.46 5 14 1415.59 26.46 5 14 257 28.6 5.02 HVO_2006 conserved hypothetical protein 5.60 1 3 3 41 1.536E7 42.21 5.60 3 21 2310.64 5.60 3 20 679 69.8 4.03 HVO_0894 acyl-CoA synthetase 12.39 1 3 5 20 1.534E7 24.12 12.39 5 10 945.41 12.39 5 10 662 74.3 4.48 HVO_2501 alpha/beta hydrolase fold protein 15.51 1 3 3 18 1.530E7 17.75 15.51 3 9 960.38 15.51 3 9 316 35.3 5.72 HVO_2373 30S ribosomal protein S8e 56.00 1 4 4 28 1.524E7 33.46 56.00 4 14 1414.42 56.00 4 14 125 13.6 10.48 HVO_0789 tryptophan synthase alpha subunit 29.24 1 4 4 12 1.524E7 10.49 29.24 4 6 589.81 29.24 4 6 277 29.6 4.21 HVO_0999 DRTGG domain protein 14.55 1 4 4 17 1.520E7 16.26 14.55 4 9 822.99 14.55 4 8 378 39.8 4.44 HVO_1095 conserved hypothetical protein 11.41 1 2 2 6 1.518E7 5.13 11.41 2 3 372.62 11.41 2 3 184 18.8 4.87 HVO_2339 sensor box histidine kinase 8.75 1 4 4 12 1.517E7 13.81 8.75 4 6 615.32 8.75 4 6 606 64.6 4.74 HVO_1610 conserved hypothetical protein 13.07 1 2 2 4 1.514E7 10.86 13.07 2 4 283 30.5 4.55 HVO_A0283 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 7.33 1 3 3 12 1.514E7 15.40 7.33 3 6 886.56 7.33 3 6 450 49.1 4.51 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 21.55 1 5 5 14 1.513E7 9.04 21.55 5 7 556.36 21.55 5 7 297 31.3 4.36 HVO_0161 ATP phosphoribosyltransferase 31.32 1 4 4 13 1.512E7 12.94 31.32 4 7 908.15 15.30 3 6 281 30.4 4.60 HVO_1615 conserved hypothetical protein 15.94 1 4 4 16 1.512E7 12.67 15.94 4 8 823.08 15.94 4 8 251 28.4 4.59 HVO_A0328 2-keto-3-deoxygluconate kinase 21.07 1 5 5 27 1.511E7 41.65 21.07 5 13 2026.16 21.07 5 14 318 34.0 4.60 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 7.44 1 2 2 7 1.489E7 2.76 7.44 2 3 306.53 7.44 2 4 363 39.7 4.25 HVO_A0158 acyl-CoA synthetase 4.92 1 1 2 12 1.487E7 11.52 4.92 2 6 514.51 4.92 2 6 650 71.2 4.63 HVO_1597 conserved hypothetical protein 20.00 1 2 2 10 1.480E7 15.00 20.00 2 5 551.57 20.00 2 5 130 13.7 4.45 HVO_2872 conserved hypothetical protein 9.17 1 3 3 7 1.473E7 7.73 5.46 2 3 444.04 9.17 3 4 458 50.8 4.81 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 9.57 1 3 3 11 1.472E7 12.32 9.57 3 5 485.75 9.57 3 6 439 47.2 4.59 HVO_0699 translation initiation factor aIF-2 alpha subunit 12.78 1 3 3 16 1.471E7 17.17 12.78 3 8 905.77 12.78 3 8 266 29.5 4.46 HVO_2767 ATP-dependent DNA helicase Dna2 4.98 1 2 3 7 1.468E7 2.28 4.98 3 4 153.79 4.98 3 3 884 97.5 4.86 HVO_1442 ABC-type transport system permease protein 6.42 1 3 3 10 1.465E7 11.19 6.42 3 5 588.77 6.42 3 5 623 63.2 5.34 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 24.51 1 5 5 16 1.452E7 18.03 10.28 3 7 803.63 24.51 5 9 457 48.4 4.35 HVO_1669 fibrillarin-like rRNA/tRNA 2'-O-methyltransferase 10.50 1 2 2 2 1.452E7 1.65 10.50 2 2 219 23.5 4.69 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 7.45 1 3 3 8 1.443E7 11.41 7.45 3 4 426.42 7.45 3 4 658 72.1 4.70 HVO_0792 3-dehydroquinate synthase type II 8.42 1 3 3 7 1.434E7 7.23 5.61 2 3 306.16 8.42 3 4 392 43.1 4.44 HVO_0406 RNA-binding protein AU-1 15.17 1 4 4 14 1.434E7 20.45 15.17 4 7 600.87 15.17 4 7 468 49.9 4.53 HVO_1140 acyl-CoA dehydrogenase 12.63 1 4 4 16 1.423E7 19.86 12.63 4 8 836.21 12.63 4 8 380 41.2 4.55 HVO_2454 anthranilate synthase component I 31.68 1 10 10 36 1.422E7 36.21 31.68 10 18 1526.68 31.68 10 18 524 55.9 4.56 HVO_A0494 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 10.16 1 2 2 10 1.416E7 3.04 10.16 2 5 347.85 10.16 2 5 443 47.8 4.21 HVO_1235 creatininase 23.48 1 4 4 17 1.412E7 14.09 23.48 4 9 583.20 23.48 4 8 264 29.2 4.84 HVO_0408 PrsW family protein 9.86 1 2 2 6 1.409E7 8.86 9.86 2 3 364.97 9.86 2 3 345 35.7 4.83 HVO_1623 conserved hypothetical protein 14.43 1 3 3 16 1.400E7 22.16 14.43 3 8 901.30 14.43 3 8 298 32.8 4.56 HVO_0322 MinD/ParA domain protein 10.33 1 3 3 14 1.400E7 17.23 10.33 3 7 737.28 10.33 3 7 581 58.8 3.70 HVO_A0425 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 13.87 1 4 4 9 1.398E7 8.78 13.87 4 4 534.11 13.87 4 5 346 38.4 5.24 HVO_C0072 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 9.09 1 2 2 10 1.397E7 16.75 9.09 2 5 589.66 9.09 2 5 297 31.6 6.39 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 33.86 1 3 3 8 1.397E7 8.76 33.86 3 4 281.18 33.86 3 4 189 21.7 4.46 HVO_1139 squalene synthase 8.66 1 2 2 10 1.395E7 7.43 8.66 2 5 412.05 8.66 2 5 358 39.7 4.54 HVO_0891 ABC-type transport system ATP-binding protein (probable substrate copper) 7.42 1 2 2 6 1.393E7 1.86 7.42 2 3 206.26 7.42 2 3 283 28.6 4.35 HVO_0240 Lrp/AsnC family transcription regulator 19.74 1 1 2 3 1.386E7 187.93 19.74 2 3 152 16.9 4.39 HVO_0145 replication factor C small subunit 23.17 1 5 5 22 1.378E7 29.78 23.17 5 11 1363.40 23.17 5 11 341 37.8 4.93 HVO_0138 tyrosine--tRNA ligase 19.51 1 5 5 22 1.377E7 17.55 19.51 5 11 1038.45 19.51 5 11 328 36.1 4.34 HVO_1323 "shikimate kinase, archaeal-type" 15.92 1 2 2 2 1.376E7 4.27 15.92 2 2 289 29.5 4.30 HVO_0103 conserved hypothetical protein 8.46 1 2 2 3 1.359E7 418.77 8.46 2 3 201 22.4 4.21 HVO_0146 phosphatidylserine decarboxylase 18.41 1 3 3 14 1.348E7 12.10 18.41 3 7 782.39 18.41 3 7 201 21.7 6.55 HVO_0197 PurE family protein 12.65 1 2 2 8 1.345E7 7.35 12.65 2 4 313.48 12.65 2 4 253 25.5 4.42 HVO_2634 conserved hypothetical protein 10.25 1 2 2 12 1.314E7 13.08 10.25 2 6 486.26 10.25 2 6 361 38.0 4.61 HVO_2071 conserved hypothetical protein 6.92 1 3 4 14 1.311E7 4.05 6.19 3 6 514.21 6.92 4 8 549 58.4 4.72 HVO_2239 UspA domain protein 25.35 1 2 2 6 1.308E7 7.83 25.35 2 3 277.89 25.35 2 3 142 15.4 4.16 HVO_1708 conserved hypothetical protein 9.99 1 5 5 24 1.306E7 25.73 9.99 5 12 1147.04 9.99 5 12 781 82.6 5.22 HVO_1293 conserved hypothetical protein 32.68 1 3 3 13 1.297E7 14.22 32.68 3 6 953.74 32.68 3 7 205 21.6 4.46 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 20.11 1 3 3 7 1.296E7 8.65 20.11 3 4 269.15 12.50 2 3 184 19.8 5.30 HVO_0970 ribulose-bisphosphate carboxylase large subunit 8.21 1 2 2 15 1.292E7 16.35 8.21 2 8 769.52 8.21 2 7 414 43.9 4.59 HVO_0648 DUF2070 family protein 9.89 1 6 6 15 1.288E7 3.67 9.89 6 8 517.12 9.26 5 7 637 67.7 4.77 HVO_2209 probable branched-chain amino acid dehydrogenase E1 component alpha subunit 7.47 1 2 2 7 1.273E7 5.63 7.47 2 3 425.17 7.47 2 4 348 38.7 4.70 HVO_1936 F420-0:gamma-glutamyl ligase 13.15 1 3 3 7 1.270E7 6.69 13.15 3 4 283.91 9.96 2 3 251 27.4 4.68 HVO_1368 probable metallo-beta-lactamase family hydrolase 7.49 1 2 2 14 1.259E7 16.34 7.49 2 7 702.93 7.49 2 7 267 29.3 4.49 HVO_1531 UDP-glucose 6-dehydrogenase 3.49 1 2 2 3 1.255E7 247.55 3.49 2 3 430 45.9 4.50 HVO_1987 signal peptide peptidase 11.04 1 2 2 12 1.255E7 13.35 11.04 2 6 559.42 11.04 2 6 299 31.3 4.56 HVO_1441 ABC-type transport system permease protein 13.92 1 4 4 18 1.242E7 18.71 13.92 4 9 1239.45 13.92 4 9 352 36.7 4.96 HVO_1866 uridylate kinase 10.13 1 2 2 8 1.237E7 8.29 10.13 2 4 482.70 10.13 2 4 237 24.6 4.42 HVO_1972 GNAT family acetyltransferase 30.81 1 5 5 15 1.228E7 12.92 30.81 4 7 776.74 30.81 5 8 211 23.3 6.02 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 6.79 1 2 2 8 1.222E7 9.88 6.79 2 4 442.89 6.79 2 4 324 33.6 3.99 HVO_0882 DUF373 family protein 6.88 1 3 3 10 1.222E7 3.51 6.88 3 5 513.48 6.88 3 5 378 40.2 4.55 HVO_2537 conserved hypothetical protein 20.23 1 3 3 22 1.222E7 30.42 20.23 3 11 1224.99 20.23 3 11 173 18.9 4.46 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 17.86 1 4 5 21 1.217E7 10.17 17.86 5 11 876.00 17.86 5 10 280 30.0 4.92 HVO_0220 ATP-dependent DNA helicase MCM 12.82 1 7 7 25 1.212E7 29.41 12.82 7 13 1454.78 12.82 7 12 702 78.8 4.73 HVO_0064 DUF296 family protein 13.67 1 2 2 7 1.211E7 6.93 13.67 2 3 363.53 13.67 2 4 139 15.6 4.37 HVO_0246 ArsR family transcription regulator 10.00 1 2 2 12 1.201E7 10.81 10.00 2 6 577.40 10.00 2 6 320 31.9 4.41 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 13.37 1 2 2 17 1.201E7 18.44 13.37 2 8 940.19 13.37 2 9 202 22.2 5.11 HVO_1257 AAA-type ATPase (MoxR subfamily) 18.34 1 6 6 20 1.196E7 14.83 18.34 6 10 957.13 18.34 6 10 338 37.4 4.67 HVO_1997 Abi/CAAX family protein 6.61 1 2 2 2 1.191E7 152.21 6.61 2 2 257 26.6 5.90 HVO_1462 "1,4-dihydroxy-2-naphthoate octaprenyltransferase" 12.82 1 4 4 15 1.191E7 10.95 9.62 3 7 805.28 12.82 4 8 312 32.7 8.28 HVO_1629 conserved hypothetical protein 9.60 1 3 3 15 1.190E7 6.83 6.97 2 7 681.30 9.60 3 8 531 56.3 4.69 HVO_A0625 conserved hypothetical protein 8.53 1 3 3 10 1.185E7 11.21 8.53 3 5 509.73 8.53 3 5 469 49.7 9.19 HVO_2266 hypothetical protein 6.29 1 2 2 15 1.181E7 5.13 6.29 2 7 584.12 6.29 2 8 493 56.7 4.54 HVO_1281 "probable glycosyltransferase, type 1" 14.85 1 4 4 17 1.164E7 13.24 14.85 4 9 915.00 14.85 4 8 357 38.7 5.87 HVO_1033 type IV pilus biogenesis complex membrane subunit 2.69 1 1 2 4 1.163E7 442.48 2.69 2 4 707 76.1 5.41 HVO_A0559 histidine ammonia-lyase 3.79 1 2 2 6 1.145E7 4.43 3.79 2 3 236.63 3.79 2 3 528 55.5 4.84 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 14.80 1 3 3 17 1.142E7 21.84 10.83 2 8 1212.86 14.80 3 9 277 30.6 4.30 HVO_0424 ABC-type transport system ATP-binding protein 20.20 1 8 8 21 1.135E7 15.74 14.24 7 10 870.14 20.20 8 11 604 67.2 4.49 HVO_0854 DNA double-strand break repair ATPase Rad50 7.17 1 3 4 7 1.133E7 7.33 6.72 3 3 310.87 7.17 4 4 893 100.0 4.58 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 4.77 1 2 2 10 1.131E7 4.39 4.77 2 5 378.38 4.77 2 5 482 50.6 4.31 HVO_2263 conserved hypothetical protein 3.12 1 2 2 6 1.131E7 6.48 3.12 2 3 242.56 3.12 2 3 801 89.5 5.54 HVO_B0223 conserved hypothetical protein 12.27 1 2 2 7 1.124E7 5.50 12.27 2 3 391.60 12.27 2 4 277 29.8 4.51 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 6.88 1 4 4 10 1.115E7 11.06 6.88 4 5 477.90 6.88 4 5 858 93.9 4.69 HVO_B0273 sensor box histidine kinase 3.70 1 2 2 6 1.110E7 7.81 3.70 2 3 356.96 3.70 2 3 568 61.4 4.92 HVO_2377 ABC-type transport system permease protein (probable substrate phosphate) 4.98 1 2 2 6 1.102E7 0.00 4.98 2 3 141.60 4.98 2 3 542 56.0 5.71 HVO_2557 50S ribosomal protein L29 27.14 1 1 2 13 1.100E7 15.92 27.14 2 7 1012.07 27.14 2 6 70 7.7 4.36 HVO_1187 conserved hypothetical protein 20.98 1 3 3 12 1.100E7 14.39 20.98 3 6 808.42 20.98 3 6 143 16.4 4.86 HVO_2188 phosphoribosylformylglycinamidine synthase 1 17.41 1 2 2 6 1.089E7 4.75 17.41 2 3 200.41 17.41 2 3 224 23.9 4.36 HVO_B0233 alpha-L-arabinofuranosidase 12.13 1 5 5 29 1.087E7 33.00 12.13 5 15 1477.43 9.00 4 14 511 57.5 4.39 HVO_B0131 conserved hypothetical protein 10.45 1 2 2 8 1.079E7 10.09 10.45 2 4 543.58 10.45 2 4 287 32.2 4.84 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 10.86 1 2 2 10 1.077E7 9.83 10.86 2 5 473.38 10.86 2 5 267 29.1 4.63 HVO_0024 thiosulfate sulfurtransferase 15.50 1 2 2 8 1.063E7 5.18 15.50 2 4 313.17 15.50 2 4 258 28.4 4.30 HVO_2311 glutamyl-tRNA reductase 11.50 1 4 4 12 1.057E7 4.26 11.50 4 6 432.23 11.50 4 6 461 49.2 4.54 HVO_2951 tryptophan--tRNA ligase 5.29 1 2 2 7 1.045E7 0.00 5.29 2 3 264.20 5.29 2 4 529 59.1 4.53 HVO_1991 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 16.87 1 4 4 20 1.044E7 32.76 16.87 4 10 1528.56 16.87 4 10 409 45.1 4.21 HVO_A0168 HTH-10 family transcription regulator 15.85 1 2 2 4 1.041E7 8.70 15.85 2 4 246 27.8 4.98 HVO_2600 methionyl aminopeptidase 8.45 1 3 3 7 1.035E7 8.63 6.42 2 3 394.81 8.45 3 4 296 32.3 4.41 HVO_B0100 aldehyde dehydrogenase 10.35 1 4 4 19 1.031E7 21.80 10.35 4 9 1075.13 10.35 4 10 483 50.4 4.31 HVO_2349 TrmB family transcription regulator 10.11 1 2 2 3 1.030E7 4.16 10.11 2 3 267 29.3 4.44 HVO_1069 Mrp-type sodium/proton antiporter system subunit A 2.37 1 2 2 6 1.027E7 7.53 2.37 2 3 312.12 2.37 2 3 801 84.5 5.68 HVO_A0629 sensor box histidine kinase 7.85 1 3 3 14 1.012E7 19.85 7.85 3 7 1049.66 7.85 3 7 548 59.9 4.63 HVO_1706 ABC-type transport system permease protein (probable substrate iron-III) 3.95 1 2 2 8 1.011E7 6.42 3.95 2 4 306.09 3.95 2 4 531 56.3 9.14 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 19.03 1 4 4 18 1.009E7 16.29 19.03 4 9 906.68 19.03 4 9 268 27.9 4.87 HVO_2315 "tritrans,polycis-undecaprenyl-diphosphate synthase" 17.48 1 5 5 21 1.004E7 12.07 17.48 5 10 977.30 17.48 5 11 309 35.1 4.98 HVO_A0586 sugar nucleotidyltransferase 7.06 1 2 2 6 9.980E6 5.11 7.06 2 3 263.72 7.06 2 3 411 43.7 4.69 HVO_2130 IclR family transcription regulator 8.82 1 2 2 6 9.966E6 8.74 8.82 2 3 413.68 8.82 2 3 272 30.1 5.55 HVO_3013 origin-associated protein OapB 33.85 1 3 3 11 9.922E6 2.43 25.38 2 5 309.48 33.85 3 6 130 14.3 4.56 HVO_0810 conserved hypothetical protein 7.98 1 1 2 3 9.629E6 252.44 7.98 2 3 188 19.8 5.00 HVO_1169 "probable glycosyltransferase, type 1" 18.48 1 4 4 12 9.589E6 4.53 11.68 3 5 356.75 18.48 4 7 368 40.8 4.73 HVO_A0162 MATE efflux family protein 8.81 1 3 3 10 9.552E6 9.88 8.81 3 5 619.32 8.81 3 5 488 51.8 5.26 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 8.31 1 2 2 2 9.551E6 213.15 8.31 2 2 337 35.9 4.69 HVO_0662 HTH domain protein / thiamine-phosphate synthase 5.02 1 2 2 6 9.480E6 4.15 5.02 2 3 227.89 5.02 2 3 299 31.9 4.44 HVO_0336 conserved hypothetical protein (nonfunctional) 10.39 1 2 2 2 9.410E6 1.70 10.39 2 2 462 51.2 4.58 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 16.88 1 2 2 6 9.381E6 8.82 16.88 2 3 396.55 16.88 2 3 231 25.0 4.25 HVO_0738 conserved hypothetical protein 38.71 1 2 2 4 9.362E6 2.97 38.71 2 2 227.66 38.71 2 2 93 10.0 4.09 HVO_A0092 acyl-CoA dehydrogenase 15.22 1 5 5 16 9.287E6 6.32 15.22 5 8 623.65 15.22 5 8 381 42.2 4.83 HVO_B0321 GFO family oxidoreductase 10.87 1 4 4 16 9.249E6 15.82 8.42 3 7 799.15 10.87 4 9 368 41.0 4.48 HVO_1295 histidinol-phosphate aminotransferase 13.02 1 3 3 5 9.156E6 5.00 13.02 3 3 154.60 8.59 2 2 361 39.4 4.51 HVO_2861 conserved hypothetical protein 20.36 1 3 3 10 9.132E6 14.88 20.36 3 5 572.47 20.36 3 5 275 29.1 4.27 HVO_0549 2-keto-3-deoxygluconate kinase 9.38 1 2 2 4 9.090E6 291.09 9.38 2 4 320 34.1 4.34 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 6.67 1 2 2 14 9.051E6 14.61 6.67 2 7 682.64 6.67 2 7 600 65.3 4.68 HVO_0388 homolog to ribonuclease R 25.06 1 7 7 25 9.015E6 30.90 25.06 7 12 1333.09 25.06 7 13 439 50.3 4.73 HVO_0687 M20 family amidohydrolase 9.68 1 3 3 13 8.959E6 17.34 7.21 2 6 777.95 9.68 3 7 444 47.5 4.58 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 19.09 1 5 5 16 8.953E6 13.86 19.09 5 8 661.25 19.09 5 8 330 36.3 4.35 HVO_B0382 TATA-binding transcription initiation factor 31.38 1 3 3 7 8.953E6 10.68 16.49 2 3 598.04 31.38 3 4 188 20.1 4.12 HVO_0598 conserved hypothetical protein 10.70 1 2 2 12 8.945E6 7.63 10.70 2 6 514.15 10.70 2 6 243 28.1 5.08 HVO_B0345 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 9.79 1 3 3 8 8.874E6 6.42 9.79 3 4 282.73 9.79 3 4 378 41.2 4.84 HVO_1735 conserved hypothetical protein 9.70 1 5 5 16 8.838E6 15.61 9.70 5 8 741.69 9.70 5 8 660 75.7 4.50 HVO_2883 conserved hypothetical protein 10.40 1 4 5 12 8.599E6 12.05 10.40 5 6 533.57 10.40 5 6 702 78.9 4.48 HVO_1424 conserved hypothetical protein 8.36 1 2 2 8 8.387E6 10.79 8.36 2 4 346.38 8.36 2 4 359 40.9 4.60 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 14.75 1 3 3 16 8.380E6 10.52 14.75 3 8 597.97 14.75 3 8 305 34.1 4.91 HVO_1895 KEOPS complex subunit Kae1/Bud32 5.25 1 2 2 4 8.339E6 6.58 5.25 2 2 328.67 5.25 2 2 552 59.0 5.07 HVO_1676 transcription initiation factor TFB 9.64 1 0 2 10 8.230E6 13.55 9.64 2 5 712.29 9.64 2 5 332 37.3 5.49 HVO_0511 NAD-dependent epimerase/dehydratase 11.07 1 2 2 8 8.056E6 11.00 11.07 2 4 371.54 11.07 2 4 262 29.3 4.78 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 4.10 1 2 2 10 8.052E6 13.00 4.10 2 5 666.55 4.10 2 5 634 66.1 4.54 HVO_2276 conserved hypothetical protein 3.01 1 3 3 9 8.003E6 5.22 2.08 2 4 362.55 3.01 3 5 1397 161.8 4.50 HVO_1447 propionyl-CoA carboxylase carboxyltransferase component 8.61 1 3 3 8 7.979E6 4.69 8.61 3 4 297.20 8.61 3 4 581 63.6 4.70 HVO_2706 translation initiation factor aIF-2B delta subunit 19.50 1 2 2 6 7.927E6 8.56 19.50 2 3 261.94 19.50 2 3 282 30.7 4.42 HVO_1886 ABC-type transport system ATP-binding protein (probable substrate sulfate/tungstate) 12.15 1 2 3 8 7.899E6 7.35 8.68 2 4 375.40 10.76 2 4 288 30.9 5.15 HVO_2124 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 6.29 1 2 2 8 7.891E6 7.61 6.29 2 4 316.75 6.29 2 4 334 35.8 5.01 HVO_2029 Lrp/AsnC family transcription regulator 30.07 1 2 3 7 7.890E6 1.70 17.65 2 3 263.26 30.07 3 4 153 16.9 4.21 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 3.67 1 4 4 12 7.877E6 11.79 3.67 4 6 495.47 3.67 4 6 1335 150.5 4.60 HVO_2397 ABC-type transport system periplasmic substrate-binding protein (probable substrate zinc) 10.05 1 3 3 8 7.876E6 5.10 10.05 2 3 367.71 10.05 3 5 368 40.1 4.53 HVO_0818 threonine synthase 9.25 1 3 3 16 7.863E6 15.63 9.25 3 8 677.27 9.25 3 8 389 40.8 4.31 HVO_1031 thioredoxin-disulfide reductase 17.54 1 3 3 6 7.849E6 6.43 17.54 3 3 213.25 17.54 3 3 342 37.4 4.46 HVO_0621 sensor box histidine kinase 6.03 1 3 3 5 7.774E6 5.16 6.03 3 3 140.33 4.31 2 2 580 63.3 5.63 HVO_1667 TrmB family transcription regulator 30.52 1 3 3 16 7.746E6 23.57 30.52 3 8 1183.82 30.52 3 8 154 16.7 4.46 HVO_2802 ABC-type transport system permease protein (probable substrate branched-chain amino acids) 5.84 1 2 2 20 7.633E6 30.53 5.84 2 10 1223.09 5.84 2 10 445 47.4 8.51 HVO_1867 lysine--tRNA ligase 5.05 1 3 3 7 7.515E6 3.11 5.05 3 3 313.23 5.05 3 4 555 62.1 4.46 HVO_B0228 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 14.38 1 3 3 12 7.393E6 16.79 14.38 3 6 814.35 14.38 3 6 459 50.2 4.36 HVO_1338 replication protein A 7.26 1 3 3 9 7.388E6 7.16 7.26 3 5 435.93 7.26 3 4 427 46.0 4.36 HVO_0219 conditioned medium-induced protein 4 7.96 1 2 2 2 7.375E6 82.97 7.96 2 2 201 22.5 4.22 HVO_0151 urease accessory protein UreD 25.08 1 3 3 11 7.367E6 13.67 25.08 3 6 696.48 10.37 2 5 299 31.3 4.98 HVO_2094 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 7.71 1 2 2 8 7.334E6 9.33 7.71 2 4 345.85 7.71 2 4 415 46.0 4.07 HVO_A0003 ParA domain protein 10.58 1 2 2 6 7.324E6 6.99 10.58 2 3 260.79 10.58 2 3 274 30.3 4.53 HVO_0745 "FtsZ family protein, type III" 11.39 1 3 3 8 7.284E6 9.92 11.39 3 4 390.68 11.39 3 4 360 37.1 4.51 HVO_0494 conserved hypothetical protein 14.39 1 2 2 4 7.130E6 0.00 14.39 2 2 101.68 14.39 2 2 264 27.4 3.95 HVO_2712 3'-5' RNA ligase 11.73 1 4 4 12 7.120E6 5.07 11.73 4 5 450.87 11.73 4 7 486 53.4 4.92 HVO_1862 probable metalloprotease 10.03 1 3 3 8 7.089E6 8.17 8.18 2 3 396.53 10.03 3 5 379 40.9 5.21 HVO_A0491 ABC-type transport system ATP-binding protein (probable substrate sugar) 4.18 1 1 2 4 7.056E6 1.77 4.18 2 2 109.42 4.18 2 2 383 41.1 4.48 HVO_A0267 D-galactonate dehydratase 8.62 1 2 2 4 7.048E6 5.11 8.62 2 2 159.89 8.62 2 2 383 42.5 4.86 HVO_1474 rhomboid family protein 3.46 1 2 2 4 7.042E6 3.79 3.46 2 2 199.97 3.46 2 2 549 58.6 9.89 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 9.05 1 2 2 2 6.984E6 3.79 9.05 2 2 475 49.3 4.49 HVO_2803 ABC-type transport system permease protein (probable substrate branched-chain amino acids) 6.79 1 3 3 11 6.979E6 8.76 6.79 3 6 597.59 5.16 2 5 368 38.2 9.60 HVO_2467 NADPH:quinone reductase 9.97 1 2 2 4 6.954E6 7.00 9.97 2 2 303.24 9.97 2 2 321 33.0 4.51 HVO_A0426 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 15.13 1 4 4 21 6.920E6 21.81 15.13 4 11 785.35 15.13 4 10 337 36.8 5.16 HVO_2052 conserved hypothetical protein 7.85 1 3 3 12 6.828E6 13.14 7.85 3 6 595.34 7.85 3 6 586 66.6 8.18 HVO_0215 iron-sulfur protein (4Fe-4S) 5.68 1 3 3 28 6.648E6 2.13 5.68 3 13 747.69 5.68 3 15 704 78.2 4.58 HVO_2448 probable oxidoreductase (aldo-keto reductase family protein) 4.89 1 2 2 9 6.630E6 5.74 4.89 2 4 419.14 4.89 2 5 327 36.5 4.94 HVO_1925 probable GTP-binding protein 8.31 1 2 2 5 6.614E6 8.35 8.31 2 5 325 36.5 4.72 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 9.30 1 2 2 6 6.542E6 6.62 9.30 2 3 317.79 9.30 2 3 344 39.1 4.73 HVO_2766 ATP-dependent DNA helicase 4.14 1 3 3 8 6.477E6 9.29 4.14 3 4 337.16 4.14 3 4 918 102.7 5.07 HVO_B0102 glycosidase family protein 5.63 1 2 2 2 6.338E6 196.12 5.63 2 2 355 38.7 4.75 HVO_0403 glucokinase 17.08 1 2 2 2 6.334E6 50.72 17.08 2 2 322 33.6 4.35 HVO_1973 conserved hypothetical protein 21.56 1 2 2 8 6.291E6 10.03 21.56 2 4 388.81 21.56 2 4 167 18.1 4.36 HVO_2383 DNA repair and recombination protein RadB 14.41 1 2 2 3 6.263E6 5.56 14.41 2 3 229 24.6 5.02 HVO_2654 homolog to respiratory nitrate reductase b-type cytochrome subunit 5.91 1 2 2 18 6.251E6 25.08 5.91 2 9 1112.22 5.91 2 9 474 51.6 5.69 HVO_1380 methylmalonyl-CoA mutase subunit A 14.52 1 3 3 12 6.240E6 8.70 14.52 3 6 483.40 14.52 3 6 558 61.9 4.41 HVO_1927 DUF389 family protein 10.60 1 4 4 12 6.152E6 11.49 10.60 4 6 372.74 10.60 4 6 434 45.6 4.60 HVO_1548 conserved hypothetical protein 18.81 1 2 2 4 6.040E6 4.66 18.81 2 2 170.91 18.81 2 2 202 22.2 4.96 HVO_2914 conserved hypothetical protein 28.57 1 2 2 2 6.037E6 92.42 28.57 2 2 140 16.1 4.61 HVO_1098 diaminopimelate decarboxylase 8.43 1 3 3 9 5.952E6 2.25 8.43 3 5 401.50 3.86 2 4 415 44.4 5.02 HVO_2685 mechanosensitive channel protein MscS 5.50 1 2 2 8 5.931E6 9.71 5.50 2 4 392.73 5.50 2 4 382 40.4 4.81 HVO_0464 threonine ammonia-lyase 6.95 1 2 2 6 5.890E6 2.25 6.95 2 3 193.91 6.95 2 3 403 43.7 4.72 HVO_B0139 PQQ repeat protein 6.76 1 2 2 8 5.818E6 11.75 6.76 2 4 616.99 6.76 2 4 429 44.6 4.93 HVO_1940 DNA mismatch repair protein MutS 2.93 1 2 2 4 5.799E6 4.37 2.93 2 2 153.81 2.93 2 2 921 99.4 4.42 HVO_1287 PfpI family protease 9.60 1 2 2 6 5.762E6 7.09 9.60 2 3 390.94 9.60 2 3 198 21.5 4.53 HVO_0003 DNA-directed DNA polymerase D exonuclease subunit DP1 2.06 1 1 2 5 5.661E6 0.00 2.06 2 3 100.39 2.06 2 2 533 57.8 4.77 HVO_2017 conserved hypothetical protein 6.54 1 2 2 9 5.632E6 5.16 6.54 2 5 325.05 6.54 2 4 459 48.2 4.98 HVO_2298 UPF0135 family protein 7.91 1 2 2 4 5.518E6 4.54 7.91 2 2 266.30 7.91 2 2 253 26.5 4.37 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 4.32 1 3 3 4 5.488E6 1.90 2.57 2 2 84.61 2.97 2 2 740 85.6 4.70 HVO_2417 conserved hypothetical protein 11.28 1 2 2 5 5.353E6 5.17 11.28 2 2 283.07 11.28 2 3 195 21.6 3.65 HVO_2510 GNAT family acetyltransferase 12.50 1 2 2 6 5.242E6 6.91 12.50 2 3 338.63 12.50 2 3 304 33.7 4.49 HVO_2580 L-aspartate oxidase 5.40 1 2 2 2 5.076E6 3.72 5.40 2 2 537 55.8 4.63 HVO_A0160 sensor box histidine kinase 7.06 1 2 2 2 4.995E6 184.74 7.06 2 2 708 76.5 4.79 HVO_1957 proteasome-activating nucleotidase 9.22 1 3 3 18 4.878E6 23.96 9.22 3 9 1162.97 9.22 3 9 412 45.6 4.48 HVO_1932 2-D-hydroxyacid dehydrogenase 13.31 1 2 2 2 4.812E6 2.38 13.31 2 2 308 33.0 4.60 HVO_0977 N5-carboxyaminoimidazole ribonucleotide mutase 28.57 1 3 3 7 4.774E6 6.13 28.57 3 4 273.35 16.26 2 3 203 21.5 4.36 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 12.94 1 3 3 5 4.667E6 2.52 6.64 2 2 284.98 12.94 3 3 286 30.8 4.46 HVO_0766 Hsp20-type molecular chaperone 13.58 1 2 3 7 4.615E6 2.71 11.11 2 3 328.44 13.58 3 4 162 17.7 4.39 HVO_2873 flap endonuclease Fen1 11.04 1 2 2 8 4.603E6 8.48 11.04 2 4 474.94 11.04 2 4 326 36.4 4.40 HVO_1040 DnaJ domain protein 14.78 1 4 4 14 4.585E6 19.12 14.78 4 7 875.03 14.78 4 7 379 38.3 9.45 HVO_0708 aminodeoxychorismate lyase 10.91 1 2 2 4 4.489E6 2.63 10.91 2 2 103.73 10.91 2 2 330 35.4 4.58 HVO_1943 endoisopeptidase/DUF4129 domain protein 5.76 1 3 3 6 4.365E6 7.60 4.29 2 3 324.41 3.49 2 3 746 78.9 4.65 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 6.49 1 2 2 8 4.361E6 9.45 6.49 2 4 404.99 6.49 2 4 339 38.1 4.50 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 11.04 1 3 3 8 4.317E6 8.76 11.04 3 4 314.07 11.04 3 4 444 47.1 4.77 HVO_2227 siroheme decarboxylase AhbA 12.10 1 2 2 2 4.315E6 128.69 12.10 2 2 347 39.1 4.69 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 9.86 1 2 2 4 4.253E6 2.71 9.86 2 2 75.05 9.86 2 2 365 39.0 4.61 HVO_2812 AstE family protein 4.40 1 1 2 4 4.146E6 1.97 4.40 2 2 120.43 4.40 2 2 341 37.3 5.14 HVO_A0304 homolog to thermosome 7.46 1 2 3 7 4.062E6 1.99 7.46 3 4 163.19 6.78 2 3 590 61.9 4.78 HVO_1945 conserved hypothetical protein 5.75 1 2 2 22 4.047E6 22.57 5.75 2 11 1554.97 5.75 2 11 365 37.0 4.46 HVO_B0324 conserved hypothetical protein 6.46 1 1 2 8 3.733E6 4.52 6.46 2 4 250.13 6.46 2 4 449 48.0 4.58 HVO_1656 YyaL family protein 3.27 1 2 2 2 3.706E6 140.98 3.27 2 2 703 77.3 4.49 HVO_0399 conserved hypothetical protein 8.09 1 2 2 4 3.606E6 2.04 8.09 2 4 346 36.0 3.95 HVO_B0059 cobalt-precorrin 5A hydrolase 8.90 1 2 2 6 3.576E6 4.36 8.90 2 3 208.76 8.90 2 3 326 34.5 4.51 HVO_2350 YyaL family protein 6.34 1 2 3 6 3.549E6 1.81 6.34 3 3 165.61 5.62 2 3 552 58.8 4.59 HVO_A0551 acyl-CoA synthetase 4.46 1 2 2 6 3.516E6 7.93 4.46 2 3 271.21 4.46 2 3 538 59.6 4.65 HVO_B0011 sarcosine oxidase 9.74 1 2 2 2 3.470E6 70.42 9.74 2 2 380 42.1 4.67 HVO_1375 O-succinylbenzoic acid--CoA ligase 3.75 1 1 2 2 3.409E6 0.00 3.75 2 2 614 64.7 4.28 HVO_1761 FKBP-type peptidylprolyl isomerase 12.10 1 2 2 4 3.137E6 2.68 12.10 2 2 174.75 12.10 2 2 157 17.1 4.23 HVO_1425 conserved hypothetical protein 7.92 1 2 2 4 3.114E6 3.90 7.92 2 2 159.25 7.92 2 2 265 30.4 4.61 HVO_0636 conserved hypothetical protein 16.32 1 1 2 2 2.996E6 2.53 16.32 2 2 190 20.1 7.28 HVO_1258 conserved hypothetical protein 9.77 1 3 3 5 2.927E6 4.76 7.49 2 2 239.71 9.77 3 3 307 31.8 4.23 HVO_2056 "probable epimerase (homolog to dTDP-4-dehydrorhamnose 3,5-epimerase)" 11.54 1 3 3 5 2.914E6 0.00 11.54 2 2 267.75 11.54 3 3 156 18.3 4.55 HVO_0126 conserved hypothetical protein 14.75 1 2 2 6 2.875E6 9.56 14.75 2 3 283.78 14.75 2 3 339 35.1 5.06 HVO_B0164 respiratory nitrate reductase catalytic subunit 3.26 1 2 2 2 2.671E6 1.71 3.26 2 2 983 111.1 4.61 HVO_0566 glycoside transferase domain protein 1.80 1 1 2 6 2.622E6 0.00 1.80 2 3 187.41 1.80 2 3 668 73.5 4.53 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 8.78 1 1 2 5 2.622E6 8.17 8.78 2 5 353 36.7 4.65 HVO_B0021 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 5.12 1 2 2 6 2.370E6 2.51 5.12 2 3 118.06 5.12 2 3 644 70.6 4.56 HVO_1372 pyrroline-5-carboxylate reductase 9.73 1 3 3 5 2.332E6 6.78 9.73 3 3 162.79 9.73 2 2 257 26.8 4.01 HVO_C0044 PLD domain protein 9.31 1 2 2 2 2.100E6 111.22 9.31 2 2 333 36.4 4.94 HVO_A0288 probable oxidoreductase (short-chain dehydrogenase family) 11.79 1 2 2 4 2.012E6 5.47 11.79 2 2 183.00 11.79 2 2 280 29.9 4.74 HVO_A0580 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 12.39 1 1 3 3 1.665E6 129.20 12.39 3 3 234 25.8 4.61 HVO_2849 probable PrkA-type serine/threonine protein kinase 2.75 1 1 2 2 1.584E6 132.98 2.75 2 2 690 79.9 4.79 HVO_0797 conserved hypothetical protein 8.67 1 1 2 2 1.511E6 88.48 8.67 2 2 173 17.6 4.44 HVO_A0001 Orc1-type DNA replication protein 6.01 1 1 3 5 1.484E6 0.00 6.01 2 2 91.11 5.77 2 3 416 47.0 4.97 HVO_C0036 conserved hypothetical protein 3.53 1 1 2 2 1.094E6 2.75 3.53 2 2 1304 145.0 4.68 HVO_1223 taxis sensor histidine kinase CheA 5.82 1 1 2 4 1.066E6 0.00 5.82 2 2 95.74 5.82 2 2 756 80.9 4.20 HVO_0748 type IV pilus biogenesis complex ATPase subunit 4.85 1 1 2 2 1.047E6 89.59 4.85 2 2 660 68.4 4.87 HVO_0608 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 6.92 1 1 2 4 9.289E5 0.00 6.92 2 2 74.35 6.92 2 2 347 37.2 4.54 HVO_0535 DUF4013 family protein 3.49 1 0 2 3 6.526E5 0.00 3.49 2 3 229 23.2 8.72 HVO_2565 conserved hypothetical protein 16.07 1 2 2 2 5.095E5 2.33 16.07 2 2 280 30.3 4.70 HVO_0689 chromosome segregation protein Smc 1.29 1 0 2 3 4.135E5 164.80 1.29 2 3 1240 138.1 4.39 HVO_2986 imidazoleglycerol-phosphate dehydratase 6.09 1 2 2 7 3.542E5 3.68 6.09 2 3 319.78 6.09 2 4 197 21.3 4.82 HVO_0014 ATP-dependent DNA helicase Hel308a 3.39 1 2 2 4 0.000E0 7.27 3.39 2 2 365.36 3.39 2 2 827 90.3 4.67 HVO_2012 receiver box response regulator 16.79 1 2 2 2 0.000E0 0.00 16.79 2 2 131 14.2 4.74 HVO_B0328 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 5.87 1 2 2 2 0.000E0 0.00 5.87 2 2 698 78.6 4.63 HVO_2318 "tritrans,polycis-undecaprenyl-diphosphate synthase" 16.83 1 2 2 3 0.000E0 179.57 16.83 2 3 202 23.1 4.63