Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0359 translation elongation factor aEF-1 alpha subunit 79.33 1 19 23 1247 7.751E10 1157.70 75.06 22 576 91982.31 79.33 23 671 421 45.7 4.73 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 72.68 1 15 15 190 1.186E10 190.96 72.68 15 94 12905.60 72.68 15 96 355 38.2 4.68 HVO_0880 conserved hypothetical protein 72.64 1 24 24 247 2.918E9 249.89 72.64 24 124 15679.18 72.64 24 123 307 36.3 4.74 HVO_0356 translation elongation factor aEF-2 71.94 1 46 46 889 3.133E10 821.22 70.56 45 444 51517.81 71.94 46 445 727 80.4 4.73 HVO_2900 fumarate hydratase 66.95 1 21 21 186 9.173E9 180.87 66.95 21 94 11058.56 66.95 21 92 469 50.1 4.78 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 66.40 1 16 16 179 1.274E10 134.88 63.78 15 88 10264.60 66.40 16 91 381 41.0 4.23 HVO_2862 serine hydroxymethyltransferase 65.30 1 16 16 297 8.422E9 232.62 63.13 15 146 16623.58 65.30 16 151 415 44.3 4.53 HVO_2413 translation elongation factor aEF-1 alpha subunit 64.76 1 15 19 178 1.050E10 114.06 57.38 17 84 9397.66 58.33 18 94 420 45.6 4.75 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 64.57 1 15 15 202 8.403E9 168.60 64.57 15 103 11516.37 64.57 15 99 350 37.6 4.54 HVO_0677 aspartate--tRNA ligase 64.52 1 20 20 277 9.462E9 229.61 64.52 20 142 15231.97 62.21 18 135 434 48.7 4.50 HVO_0025 thiosulfate sulfurtransferase 61.89 1 12 12 250 2.126E10 173.77 59.44 11 127 12410.81 61.89 12 123 286 32.1 4.28 HVO_A0207 CRISPR-associated protein Cas7 60.00 1 12 12 87 1.608E9 83.55 51.18 11 43 5179.73 60.00 12 44 340 38.2 4.54 HVO_0329 branched-chain amino acid aminotransferase 59.94 1 16 16 115 4.482E9 104.69 59.94 16 57 7080.28 59.94 15 58 312 35.0 4.58 HVO_0581 "cell division protein FtsZ, type II" 59.75 1 15 15 91 2.583E9 77.26 59.75 15 46 5238.73 59.75 15 45 400 42.5 4.75 HVO_0433 F420H2:NADP oxidoreductase 59.46 1 6 6 31 1.726E9 25.07 59.46 6 15 1489.68 59.46 6 16 222 23.3 4.72 HVO_2783 30S ribosomal protein S4 59.43 1 10 10 66 3.756E9 50.58 59.43 10 32 4076.34 59.43 10 34 175 20.1 5.24 HVO_0778 thermosome subunit 3 59.16 1 22 24 188 3.055E9 201.09 57.82 23 94 12190.32 59.16 24 94 524 55.2 4.59 HVO_1921 serine--tRNA ligase 59.13 1 22 22 97 2.364E9 83.47 59.13 22 48 5800.04 59.13 22 49 460 52.0 4.46 HVO_2724 beta-lactamase domain protein 58.89 1 19 19 154 5.885E9 109.89 58.67 18 74 8871.10 52.22 17 80 450 50.1 5.40 HVO_0175 DNA polymerase sliding clamp 58.70 1 8 8 142 4.962E9 96.59 58.70 8 70 7153.39 58.70 8 72 247 26.7 4.39 HVO_0133 thermosome subunit 1 58.57 1 23 25 183 5.712E9 156.13 50.89 22 92 11685.97 58.57 24 91 560 58.9 4.25 HVO_2384 CBS domain protein 58.42 1 19 19 131 8.131E9 75.67 58.42 19 64 6914.85 57.11 18 67 380 42.5 5.01 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 58.01 1 12 12 245 1.079E10 193.98 58.01 12 123 12507.08 58.01 12 122 312 34.5 4.98 HVO_0861 SufB domain protein 57.71 1 15 15 89 3.916E9 82.85 54.23 14 46 5404.91 57.71 15 43 402 44.7 4.23 HVO_1273 inosine-5'-monophosphate dehydrogenase 57.43 1 17 17 203 5.963E9 164.37 54.82 16 98 11306.68 57.43 17 105 498 53.3 4.55 HVO_2588 isocitrate dehydrogenase (NADP) 57.04 1 22 22 179 1.156E10 186.42 51.79 20 89 11418.50 55.13 21 90 419 45.8 4.59 HVO_0850 proteasome-activating nucleotidase 56.54 1 15 16 72 1.345E9 58.81 49.14 14 34 3785.77 56.54 16 38 405 45.6 4.60 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 56.51 1 15 15 148 7.809E9 175.76 56.51 15 74 11619.61 54.69 14 74 384 41.4 4.41 HVO_0859 FeS assembly ATPase SufC 56.15 1 16 16 99 4.089E9 90.09 54.15 15 48 6653.10 56.15 15 51 301 33.4 4.35 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 56.08 1 21 21 144 6.082E9 131.45 56.08 21 71 8274.34 56.08 21 73 592 66.6 4.61 HVO_0455 thermosome subunit 2 54.94 1 23 24 235 6.145E9 169.82 54.94 24 116 12286.71 51.35 23 119 557 59.3 4.37 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 54.45 1 11 11 70 2.643E9 55.22 54.45 11 35 3712.34 54.45 11 35 281 30.6 4.59 HVO_2968 phosphoglycerate dehydrogenase 53.33 1 20 20 232 1.060E10 246.14 51.62 19 116 16215.01 53.33 20 116 525 55.3 4.36 HVO_2487 aspartate-semialdehyde dehydrogenase 53.20 1 9 9 84 6.228E9 53.89 53.20 9 40 4113.17 53.20 9 44 344 36.6 4.41 HVO_2544 30S ribosomal protein S5 51.87 1 10 10 58 7.009E9 33.87 40.65 9 29 3021.84 49.53 9 29 214 23.3 9.29 HVO_1145 30S ribosomal protein S1e 51.82 1 10 10 52 1.331E9 52.72 51.82 10 25 3378.36 51.82 10 27 220 24.8 4.86 HVO_1637 FKBP-type peptidylprolyl isomerase 51.31 1 9 10 72 4.685E9 60.15 28.10 8 30 4257.61 51.31 10 42 306 33.8 3.76 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 51.22 1 11 11 126 5.421E9 102.07 48.43 10 60 7790.56 51.22 11 66 287 31.0 4.73 HVO_1502 3-isopropylmalate dehydrogenase 50.93 1 13 13 70 2.627E9 71.08 43.21 12 31 5077.55 50.93 13 39 324 33.7 4.23 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 24 1.369E9 4.07 37.91 4 10 843.78 50.33 5 14 153 16.9 4.21 HVO_3007 malate dehydrogenase 50.33 1 12 12 226 9.973E9 262.54 50.33 12 111 13649.66 50.33 12 115 304 32.6 4.40 HVO_2913 superoxide dismutase (Mn) 50.25 1 0 6 45 6.438E9 43.44 37.19 5 22 2913.26 45.73 5 23 199 22.3 4.48 HVO_A0475 superoxide dismutase (Mn) 50.00 1 0 6 45 6.438E9 43.44 37.00 5 22 2913.26 45.50 5 23 200 22.4 4.45 HVO_0347 DNA-directed RNA polymerase subunit B'' 49.90 1 21 21 140 1.849E9 96.67 49.90 21 70 7552.11 49.90 21 70 521 58.9 5.00 HVO_2552 30S ribosomal protein S4e 49.80 1 8 8 104 1.625E10 99.93 49.80 8 53 5870.22 49.80 8 51 247 26.6 4.58 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 49.48 1 5 5 30 1.639E9 25.12 38.66 4 11 2161.38 49.48 5 19 194 20.7 4.12 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 49.46 1 7 7 22 4.781E8 12.46 36.41 5 10 1133.80 49.46 7 12 184 19.8 5.30 HVO_0869 glutamate synthase large subunit 48.97 1 53 53 298 3.743E9 268.23 48.51 52 147 17827.25 47.72 52 151 1511 163.8 4.70 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 48.36 1 14 14 76 1.748E9 50.97 48.36 14 38 3766.70 48.36 14 38 457 48.4 4.35 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 48.09 1 12 12 41 7.606E8 36.29 48.09 12 20 1911.34 48.09 12 21 445 47.8 4.86 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 47.89 1 6 6 50 2.067E9 36.33 47.89 6 24 2627.07 47.89 6 26 190 20.6 4.30 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 47.87 1 7 7 40 1.750E9 27.30 45.21 6 19 2020.36 47.87 7 21 188 20.5 4.60 HVO_2519 conserved hypothetical protein 47.38 1 13 13 68 1.502E9 39.33 42.67 12 32 3909.64 46.07 12 36 382 40.7 4.35 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 47.21 1 13 13 68 3.578E9 53.32 42.30 12 32 4456.72 47.21 13 36 305 33.8 4.74 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 47.20 1 9 9 46 1.014E9 42.21 47.20 9 23 2547.61 47.20 9 23 286 31.2 4.54 HVO_0055 CBS domain protein 47.18 1 9 9 66 3.087E9 60.73 47.18 9 33 3991.87 47.18 9 33 284 30.8 4.27 HVO_2204 "FtsZ family protein, type III" 47.09 1 13 15 83 3.060E9 71.40 47.09 15 42 5009.03 45.32 14 41 395 42.0 4.68 HVO_2558 30S ribosomal protein S3 47.04 1 13 13 160 4.977E9 159.96 42.76 12 79 10884.13 45.39 12 81 304 33.4 4.06 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 47.03 1 8 8 27 3.955E8 17.62 47.03 8 14 1047.37 41.58 7 13 202 22.2 5.11 HVO_0240 Lrp/AsnC family transcription regulator 46.71 1 5 6 24 1.569E9 12.30 41.45 5 11 1165.90 46.71 6 13 152 16.9 4.39 HVO_0348 DNA-directed RNA polymerase subunit B' 46.63 1 22 22 141 2.033E9 122.06 45.16 21 71 7399.05 46.63 22 70 609 67.7 4.92 HVO_0999 DRTGG domain protein 46.56 1 12 12 83 1.802E9 81.90 46.56 12 42 4857.43 46.56 12 41 378 39.8 4.44 HVO_1132 adenylosuccinate synthase 46.50 1 18 18 261 8.134E9 201.61 43.34 17 126 14200.28 46.50 18 135 443 48.2 4.56 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 162 4.497E9 147.97 43.25 7 77 10273.60 46.37 8 85 289 29.8 4.27 HVO_0239 glutamine synthetase 46.27 1 15 15 99 6.866E9 77.00 46.27 15 48 5508.99 46.27 15 51 456 50.5 4.56 HVO_1541 glycerol kinase 46.27 1 18 18 107 3.714E9 55.81 42.94 17 50 6402.49 46.27 18 57 510 56.7 4.50 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 46.12 1 21 21 334 2.181E10 344.79 44.85 20 166 22611.02 46.12 21 168 631 68.4 4.49 HVO_1545 dihydroxyacetone kinase subunit DhaL 46.12 1 9 9 44 2.416E9 39.16 46.12 9 22 2489.96 46.12 9 22 232 24.8 4.48 HVO_1454 aspartate carbamoyltransferase catalytic subunit 46.05 1 9 9 33 4.444E8 18.48 46.05 9 17 1464.36 46.05 9 16 304 33.7 4.92 HVO_1481 UspA domain protein 45.40 1 6 6 45 3.221E9 34.41 45.40 6 22 2738.86 45.40 6 23 163 17.7 4.40 HVO_1300 triosephosphate isomerase 45.33 1 6 6 42 3.749E9 44.31 45.33 6 20 3096.28 45.33 6 22 214 21.3 4.26 HVO_A0206 CRISPR-associated protein Cas8b 45.33 1 23 23 109 2.422E9 86.79 41.42 22 56 5761.05 43.79 22 53 717 79.3 4.60 HVO_1955 aconitate hydratase 45.26 1 25 25 407 2.003E10 407.88 44.50 24 199 27753.30 45.26 25 208 654 70.4 4.45 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 44.94 1 9 9 53 6.670E8 46.81 44.94 9 27 3419.72 44.94 9 26 336 36.8 4.12 HVO_1649 methionine adenosyltransferase 44.78 1 11 11 41 7.704E8 28.34 44.78 11 20 1961.76 35.07 10 21 402 43.5 4.45 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 44.76 1 16 16 72 2.469E9 52.67 40.19 13 33 4437.67 44.76 16 39 525 56.4 4.40 HVO_2646 dihydroxy-acid dehydratase 44.35 1 16 16 133 4.337E9 122.43 44.35 16 65 7146.09 44.35 16 68 584 61.8 4.42 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 44.20 1 20 20 281 8.035E9 247.78 44.20 20 143 16949.85 44.20 20 138 586 64.0 4.49 HVO_0317 A-type ATP synthase subunit B 44.02 1 12 13 134 9.353E9 148.84 42.31 12 67 10504.32 44.02 13 67 468 51.9 4.25 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 44.02 1 12 12 40 1.137E9 30.90 41.98 11 19 2243.03 44.02 12 21 343 38.4 4.94 HVO_2861 conserved hypothetical protein 44.00 1 10 10 51 1.286E9 50.38 35.27 9 26 2963.12 40.73 9 25 275 29.1 4.27 HVO_0860 SufB domain protein 43.91 1 16 16 137 5.568E9 113.45 40.76 15 67 8738.16 43.91 16 70 476 53.2 4.69 HVO_2969 threonine synthase 43.91 1 13 13 86 3.702E9 63.18 43.91 13 42 4395.57 43.91 13 44 419 44.4 4.49 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 43.81 1 9 9 42 7.747E8 37.53 43.81 9 21 2527.94 43.81 9 21 226 25.5 4.25 HVO_0104 DNA repair and recombination protein RadA 43.73 1 12 12 86 4.129E9 62.81 38.48 11 41 5465.11 43.73 12 45 343 37.3 4.64 HVO_2191 formyltetrahydrofolate deformylase 43.73 1 11 11 49 2.458E9 42.08 43.73 10 24 2963.91 40.67 10 25 327 36.2 4.63 HVO_1507 acetolactate synthase small subunit 43.58 1 7 7 29 4.197E8 16.02 43.58 7 15 1285.24 43.58 7 14 218 23.7 4.94 HVO_2889 RecJ domain protein 43.48 1 24 24 196 7.292E9 165.60 42.80 23 96 12118.31 40.33 23 100 729 79.1 4.37 HVO_0870 proline--tRNA ligase 43.24 1 13 14 81 1.839E9 66.86 37.09 12 38 5232.16 42.21 13 43 488 54.9 4.44 HVO_B0118 SMC-like protein Sph2 43.17 1 24 24 153 2.771E9 129.35 42.24 23 77 7412.55 36.96 21 76 644 73.8 4.41 HVO_1973 conserved hypothetical protein 43.11 1 4 4 20 1.929E8 12.36 43.11 4 10 880.71 43.11 4 10 167 18.1 4.36 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 43.10 1 8 8 51 1.603E9 40.85 38.38 7 26 2685.20 41.08 7 25 297 31.3 4.36 HVO_2015 conserved hypothetical protein 42.90 1 10 10 202 2.246E10 185.63 42.90 10 100 14299.78 42.90 10 102 345 37.7 4.25 HVO_0203 replication factor C small subunit 42.81 1 11 11 47 1.053E9 36.70 42.81 11 24 2069.08 40.37 10 23 327 36.2 4.51 HVO_1373 acyl-CoA dehydrogenase 42.30 1 10 10 48 9.114E8 26.81 42.30 10 24 2107.16 42.30 10 24 383 42.5 4.61 HVO_1590 DnaK-type molecular chaperone Hsp70 42.24 1 22 22 199 6.353E9 175.04 42.24 22 100 12374.52 41.28 21 99 625 67.2 4.18 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.11 1 9 9 39 7.605E8 21.78 42.11 9 19 1815.00 42.11 9 20 266 27.8 4.84 HVO_1080 conserved hypothetical protein 42.02 1 5 5 21 4.250E8 17.82 42.02 5 11 967.97 42.02 5 10 188 21.1 4.31 HVO_2057 sugar nucleotidyltransferase 42.02 1 13 13 71 2.360E9 48.85 42.02 13 36 3383.93 42.02 13 35 357 37.8 4.44 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 41.38 1 12 12 71 3.566E9 73.42 39.77 11 34 4309.43 41.38 12 37 435 46.9 4.63 HVO_0894 acyl-CoA synthetase 41.24 1 9 20 132 2.821E9 93.38 39.73 19 64 6264.59 41.24 20 68 662 74.3 4.48 HVO_A0205 CRISPR-associated endoribonuclease Cas6 41.18 1 11 11 50 1.141E9 47.87 41.18 11 26 3134.90 41.18 11 24 272 31.0 5.44 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 41.07 1 17 17 59 1.291E9 54.00 39.57 16 29 3806.51 41.07 17 30 599 65.3 4.51 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 41.04 1 3 3 7 7.960E7 11.23 41.04 3 4 388.02 24.63 2 3 134 13.9 4.55 HVO_1504 3-isopropylmalate dehydratase large subunit 41.01 1 18 18 115 3.298E9 96.35 41.01 18 59 6281.02 39.11 17 56 473 51.6 4.55 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 40.93 1 11 11 57 1.833E9 37.25 37.07 9 26 3155.97 33.98 10 31 259 29.9 4.36 HVO_2013 "FtsZ family protein, type III" 40.86 1 7 8 43 3.143E8 37.67 40.86 8 21 2749.32 40.86 8 22 394 41.5 4.61 HVO_0354 30S ribosomal protein S7 40.69 1 6 6 19 7.404E8 15.21 26.47 5 9 1072.43 40.69 6 10 204 22.6 5.14 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 40.61 1 17 18 66 7.867E8 47.82 35.47 16 32 3098.87 40.61 18 34 623 62.1 5.30 HVO_0161 ATP phosphoribosyltransferase 40.57 1 9 9 50 7.468E8 33.06 40.57 9 25 2637.78 40.57 9 25 281 30.4 4.60 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 40.56 1 9 9 52 1.623E9 34.46 40.56 9 25 2411.82 40.56 9 27 360 39.6 4.39 HVO_0480 phosphoglycerate kinase 40.40 1 14 14 54 1.780E9 56.53 40.40 14 27 3497.53 40.40 14 27 401 43.6 4.37 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 40.36 1 10 10 37 2.486E9 27.15 40.36 10 17 1905.83 40.36 10 20 280 30.1 4.44 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 41 1.363E9 43.63 40.26 5 21 3360.19 40.26 5 20 154 17.5 4.50 HVO_1506 ketol-acid reductoisomerase 40.23 1 9 9 60 7.318E8 57.91 40.23 9 31 3661.58 40.23 9 29 348 37.9 4.34 HVO_0357 ACT domain protein 40.21 1 5 5 35 9.757E8 28.15 40.21 5 18 1540.99 40.21 5 17 189 20.2 4.59 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 22 6.720E8 13.20 40.00 4 11 1133.45 40.00 4 11 130 14.1 4.79 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 39.92 1 16 16 63 1.629E9 42.86 36.90 14 30 3192.51 39.92 16 33 496 55.0 4.53 HVO_0743 probable phosphodiesterase 39.87 1 20 20 103 2.230E9 68.65 38.53 19 50 5267.94 39.87 20 53 449 50.5 4.56 HVO_1212 KaiC-type circadian regulator CirA 39.84 1 9 9 54 3.078E9 50.66 37.40 8 25 4431.24 39.84 9 29 246 27.5 4.45 HVO_1546 dihydroxyacetone kinase subunit DhaK 39.76 1 12 12 148 3.701E9 67.59 39.76 12 73 5785.04 39.76 12 75 332 34.8 4.22 HVO_1198 UspA domain protein 39.31 1 5 5 16 1.210E9 12.10 39.31 5 8 916.50 39.31 5 8 145 15.6 4.75 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 39.23 1 10 10 72 5.752E9 47.89 39.23 10 34 3703.46 39.23 10 38 413 45.8 4.45 HVO_0400 conserved hypothetical protein 38.89 1 3 3 7 1.960E8 1.91 38.89 3 4 138.26 38.89 3 3 126 13.9 4.68 HVO_0353 30S ribosomal protein S12 38.73 1 7 7 36 1.024E9 31.23 38.73 7 18 1752.40 38.73 7 18 142 15.5 9.91 HVO_0109 cysteine desulfurase 38.73 1 12 12 39 9.231E8 29.96 38.73 12 19 2108.33 32.16 11 20 426 46.8 4.56 HVO_0313 A-type ATP synthase subunit E 38.66 1 6 6 27 7.223E8 24.01 31.44 4 11 1610.10 38.66 6 16 194 22.0 4.31 HVO_2419 hydroxymethylglutaryl-CoA synthase 38.65 1 12 12 61 2.379E9 46.64 33.93 11 29 2765.19 38.65 12 32 445 50.1 4.64 HVO_1858 30S ribosomal protein S19e 38.41 1 3 3 14 1.826E7 9.80 26.49 2 6 466.68 38.41 3 8 151 16.7 4.84 HVO_0536 ferritin 38.07 1 3 3 11 5.178E8 12.29 38.07 3 6 541.55 38.07 3 5 176 19.9 4.50 HVO_0449 prephenate dehydratase 38.06 1 8 8 35 1.061E9 27.06 35.82 7 18 1893.58 38.06 8 17 268 28.7 4.64 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 51 1.649E9 39.98 35.50 8 22 3367.56 38.05 9 29 431 46.1 4.48 HVO_2040 NAD-dependent epimerase/dehydratase 37.91 1 5 10 48 2.181E9 47.05 32.35 9 22 3226.12 37.91 10 26 306 33.8 4.51 HVO_0729 inorganic pyrophosphatase 37.85 1 8 8 59 3.090E9 59.05 37.85 8 29 4059.02 37.85 8 30 177 20.4 4.16 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 37.84 1 7 7 48 1.633E9 43.57 37.84 7 23 3061.22 37.84 7 25 259 28.0 4.50 HVO_0316 A-type ATP synthase subunit A 37.71 1 16 16 130 5.619E9 129.92 36.35 15 66 8376.75 37.71 16 64 586 64.5 4.25 HVO_0401 UspA domain protein 37.50 1 4 4 25 1.197E9 17.34 37.50 4 12 1639.44 37.50 4 13 152 16.4 4.79 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 37.50 1 11 11 37 6.683E8 23.76 37.50 11 19 1697.92 35.71 10 18 336 38.0 4.61 HVO_1914 acetyl-CoA C-acyltransferase 37.40 1 8 8 32 1.079E9 24.33 34.75 7 16 1778.97 28.91 7 16 377 39.9 4.41 HVO_0358 homoserine dehydrogenase 37.22 1 6 7 31 1.638E9 22.45 37.22 7 16 1619.22 35.33 6 15 317 32.4 4.44 HVO_2059 NAD-dependent epimerase/dehydratase 37.10 1 7 7 31 1.219E9 22.14 28.71 6 16 1556.39 34.52 6 15 310 34.1 4.40 HVO_1562 proteasome beta subunit 37.04 1 7 7 18 4.865E8 11.20 37.04 7 10 818.83 31.28 5 8 243 26.0 4.63 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 37.02 1 16 16 82 2.684E9 70.96 37.02 16 44 4424.78 31.09 12 38 624 67.6 4.27 HVO_0717 "cell division protein FtsZ, type I" 36.94 1 13 13 78 3.505E9 60.79 36.94 13 38 5020.34 36.94 13 40 379 39.8 4.40 HVO_1091 proteasome alpha subunit 36.90 1 9 10 58 2.505E9 53.88 36.90 9 29 3682.23 36.90 10 29 252 27.6 4.56 HVO_0324 arginine--tRNA ligase 36.63 1 18 18 79 1.278E9 70.09 36.63 18 40 4828.97 32.71 17 39 587 65.0 4.35 HVO_2774 enolase 36.59 1 9 9 64 4.624E9 50.28 36.59 9 32 3626.71 34.84 8 32 399 42.0 4.37 HVO_0661 dCTP deaminase (dUMP-forming) 36.41 1 4 4 12 1.186E8 4.49 36.41 4 7 324.25 23.08 3 5 195 21.2 4.59 HVO_2981 uracil phosphoribosyltransferase 36.28 1 6 6 19 1.624E9 10.38 24.34 3 7 836.06 30.97 5 12 226 24.5 4.49 HVO_0424 ABC-type transport system ATP-binding protein 36.09 1 16 16 56 8.630E8 49.06 32.78 14 29 2766.34 36.09 16 27 604 67.2 4.49 HVO_1690 DHH family phosphoesterase 36.08 1 9 9 34 3.521E8 23.37 36.08 9 18 1390.21 29.90 8 16 485 52.1 4.48 HVO_0024 thiosulfate sulfurtransferase 36.05 1 6 6 31 1.350E9 14.29 31.40 5 13 1605.75 36.05 6 18 258 28.4 4.30 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 35.94 1 15 15 46 1.243E9 32.63 29.07 13 22 2324.62 35.94 15 24 626 67.6 4.65 HVO_1082 homolog to orotate phosphoribosyltransferase 35.71 1 6 6 33 1.157E9 24.97 35.71 6 16 1714.40 35.71 6 17 210 22.3 4.42 HVO_0937 FMN-binding domain protein 35.62 1 3 3 14 1.468E8 5.96 35.62 3 7 466.67 35.62 3 7 146 16.2 4.36 HVO_0212 homolog to lactoylglutathione lyase 35.48 1 3 3 11 4.387E8 8.59 35.48 3 5 552.55 35.48 3 6 124 13.5 4.13 HVO_2336 pyridoxal biosynthesis lyase PdxS 35.43 1 7 7 37 6.898E8 28.64 31.79 6 16 2255.98 35.43 7 21 302 32.5 4.81 HVO_1932 2-D-hydroxyacid dehydrogenase 35.39 1 8 8 24 1.706E8 17.57 27.27 7 11 1092.49 35.39 8 13 308 33.0 4.60 HVO_0602 3-dehydroquinate dehydratase 35.22 1 6 6 25 3.290E8 18.89 28.34 5 12 1225.77 35.22 6 13 247 27.3 4.51 HVO_0806 pyruvate kinase 35.21 1 17 17 79 2.575E9 51.73 35.21 17 40 4219.53 34.70 16 39 585 62.0 4.54 HVO_1593 PAC2 family protein 35.08 1 4 4 11 5.398E8 5.81 28.63 3 5 383.31 35.08 4 6 248 26.6 4.46 HVO_1684 threonine--tRNA ligase 34.99 1 19 19 105 3.024E9 85.40 34.99 19 52 6472.54 34.99 19 53 643 73.4 4.45 HVO_0167 adenosylhomocysteinase 34.81 1 10 10 31 8.931E8 24.71 30.37 8 12 2203.42 34.81 10 19 428 46.6 4.39 HVO_A0156 acyl-CoA synthetase 34.79 1 5 16 92 2.736E9 61.15 33.58 15 45 4168.63 34.79 16 47 664 74.0 4.40 HVO_2961 dihydrolipoyl dehydrogenase 34.74 1 12 12 42 4.389E8 35.81 34.74 12 21 2289.62 34.74 12 21 475 49.9 4.41 HVO_0292 replication protein A 34.73 1 9 9 27 5.169E8 15.62 34.73 9 13 1288.85 31.83 8 14 311 34.6 4.31 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 34.65 1 6 6 24 3.047E8 18.75 30.31 5 11 1210.78 34.65 6 13 254 26.9 4.42 HVO_2621 phosphoenolpyruvate carboxylase 34.56 1 25 25 110 2.758E9 68.51 34.56 25 54 5977.04 34.56 25 56 897 102.3 4.64 HVO_2813 RimK family protein 34.44 1 12 12 71 3.236E9 63.48 34.44 12 35 4636.51 34.44 12 36 453 49.0 4.73 HVO_2624 CTP synthase 34.43 1 14 14 67 2.207E9 48.07 30.78 12 31 4019.22 34.43 14 36 549 60.8 4.70 HVO_0809 methionine--tRNA ligase 34.32 1 18 18 76 1.334E9 50.89 34.32 18 38 4021.61 34.32 18 38 740 81.9 4.37 HVO_0243 threonine aldolase 34.31 1 7 7 23 2.491E8 15.31 34.31 7 11 1259.96 34.31 7 12 341 35.6 4.55 HVO_0314 A-type ATP synthase subunit C 34.20 1 10 10 56 8.266E8 40.26 30.17 9 27 3726.09 34.20 10 29 348 38.7 4.50 HVO_2436 malic enzyme (NADP) 34.09 1 15 19 86 1.282E9 81.00 34.09 19 43 5134.46 28.36 17 43 751 81.4 4.55 HVO_0980 NADH dehydrogenase-like complex subunit CD 33.75 1 10 14 46 9.068E8 30.84 30.70 13 23 2009.83 31.06 12 23 557 63.4 4.53 17318569 keratin 1 [Homo sapiens] 33.39 1 1 23 124 2.393E9 113.51 33.39 23 61 8166.10 33.39 23 63 644 66.0 8.12 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 33.33 1 7 7 33 8.405E8 29.24 32.73 6 16 1981.94 33.33 7 17 330 36.3 4.35 HVO_1084 adenylosuccinate lyase 33.26 1 11 11 60 6.962E8 39.24 33.26 11 30 2892.34 33.26 11 30 463 50.8 4.70 HVO_0789 tryptophan synthase alpha subunit 33.21 1 6 6 28 4.896E8 25.49 28.52 5 13 1784.77 33.21 6 15 277 29.6 4.21 HVO_1284 GTP cyclohydrolase III 32.95 1 6 6 17 1.989E8 18.10 32.95 6 8 1177.86 32.95 6 9 261 28.9 4.70 HVO_1031 thioredoxin-disulfide reductase 32.75 1 7 7 33 7.454E8 27.12 32.75 7 16 1786.01 32.75 7 17 342 37.4 4.46 HVO_0417 metal-dependent carboxypeptidase 32.67 1 13 13 51 8.834E8 31.26 32.67 13 25 2305.58 32.67 13 26 502 57.3 4.42 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 32.65 1 9 9 36 5.999E8 27.88 32.65 9 19 1681.46 30.88 8 17 340 38.8 4.58 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 32.62 1 31 31 183 1.932E9 136.34 28.94 28 92 9439.40 31.27 30 91 1033 114.3 4.45 HVO_1189 aldehyde dehydrogenase 32.48 1 15 15 62 2.335E9 59.44 32.48 15 31 3507.86 32.48 15 31 508 56.1 4.59 HVO_1657 phosphoribosylamine--glycine ligase 32.24 1 13 13 56 1.604E9 34.03 32.24 13 27 2992.07 32.24 13 29 428 45.5 4.20 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 31.99 1 0 22 122 2.393E9 111.52 31.99 22 60 8027.07 31.99 22 62 644 66.0 8.12 HVO_2348 GTP cyclohydrolase MptA 31.82 1 7 7 31 6.850E8 11.56 31.82 7 17 938.82 30.19 5 14 308 33.5 4.68 HVO_1727 TATA-binding transcription initiation factor 31.72 1 6 7 48 3.444E9 36.11 29.03 6 24 3483.29 27.96 6 24 186 19.9 4.36 HVO_1133 conserved hypothetical protein 31.68 1 2 2 3 1.428E8 4.45 31.68 2 3 101 11.7 4.58 HVO_0393 UvrABC system protein A 31.64 1 23 23 76 4.180E8 54.76 30.72 22 38 3118.31 27.98 21 38 983 108.6 4.82 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 31 4.051E9 33.92 31.45 3 15 2719.55 31.45 3 16 124 14.2 5.22 HVO_1488 D-gluconate dehydratase 31.31 1 9 11 48 1.793E9 26.18 31.31 11 23 2286.03 31.31 11 25 412 45.8 4.60 HVO_2417 conserved hypothetical protein 31.28 1 4 4 12 3.493E8 9.21 31.28 4 6 723.67 31.28 4 6 195 21.6 3.65 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 31.03 1 10 11 38 7.543E8 26.80 31.03 11 20 1560.26 29.02 9 18 348 38.2 4.32 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 31.00 1 14 14 69 7.357E8 55.58 25.00 12 32 4089.49 31.00 14 37 600 65.3 4.68 HVO_2790 ATP-binding protein Mrp 30.92 1 6 6 27 4.808E8 19.07 30.92 6 14 1372.31 30.92 6 13 346 36.8 4.50 HVO_2688 TrmB family transcription regulator 30.88 1 9 9 40 2.090E9 38.37 30.88 9 20 3133.31 30.88 9 20 353 39.3 4.58 HVO_2225 AstE family protein 30.79 1 6 6 22 1.150E9 14.34 30.79 6 11 1096.90 30.79 6 11 341 36.9 4.53 HVO_1576 NAD-dependent epimerase/dehydratase 30.72 1 4 9 40 1.353E9 35.04 30.72 9 19 2328.92 30.72 9 21 306 33.9 4.51 HVO_1306 chorismate synthase 30.65 1 7 7 41 2.514E8 34.87 30.65 7 21 1842.44 30.65 7 20 385 41.9 4.83 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 30.38 1 10 10 40 8.216E8 43.31 30.38 10 20 2057.13 30.38 10 20 474 53.4 4.59 HVO_1901 translation initiation factor aIF-2 gamma subunit 30.17 1 9 9 72 2.742E9 51.92 30.17 9 34 3909.46 30.17 9 38 411 43.9 4.36 HVO_2347 conserved hypothetical protein 30.00 1 3 3 12 2.468E8 13.53 30.00 3 6 962.59 30.00 3 6 140 15.5 4.37 HVO_2773 30S ribosomal protein S2 30.00 1 4 4 60 4.609E9 55.77 30.00 4 30 3679.60 30.00 4 30 260 28.3 4.16 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 29.95 1 14 14 58 9.903E8 29.46 28.74 13 29 2419.84 28.90 13 29 661 71.0 4.35 HVO_C0069 GFO family oxidoreductase 29.94 1 8 8 37 2.506E8 27.79 27.78 7 18 1659.04 29.94 8 19 324 36.0 5.10 HVO_0008 aspartate kinase 29.85 1 9 9 71 3.925E9 49.81 29.85 9 34 3595.96 29.85 9 37 392 41.7 4.46 HVO_2130 IclR family transcription regulator 29.78 1 7 7 24 4.170E8 15.09 25.74 6 10 1541.63 29.78 7 14 272 30.1 5.55 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 29.75 1 8 8 26 1.785E8 26.95 29.75 8 13 1754.25 29.75 8 13 363 39.3 4.97 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 29.72 1 10 10 44 9.405E8 28.73 29.72 10 22 2331.40 29.72 10 22 471 51.0 4.48 HVO_1573 DNA gyrase subunit A 29.70 1 19 19 74 1.275E9 59.46 29.70 19 37 3575.95 28.65 18 37 862 94.8 4.56 HVO_1291 fumarylacetoacetase family protein 29.63 1 3 3 8 1.275E9 7.32 29.63 3 4 446.21 29.63 3 4 243 26.3 4.55 HVO_1125 cysteine--tRNA ligase 29.55 1 10 10 46 8.425E8 34.48 29.55 10 23 2299.93 29.55 10 23 494 55.2 4.56 HVO_1172 NAD-dependent epimerase/dehydratase 29.52 1 7 7 35 1.942E9 25.61 26.98 6 16 1733.89 29.52 7 19 315 34.9 4.34 HVO_2643 NADPH:quinone reductase 29.19 1 6 6 30 2.917E8 24.04 29.19 6 15 1534.25 29.19 6 15 346 37.2 4.55 HVO_0350 DNA-directed RNA polymerase subunit A'' 29.12 1 12 13 52 2.772E9 45.75 27.45 12 26 3066.49 28.88 12 26 419 46.1 4.35 HVO_1123 thioredoxin-disulfide reductase 28.94 1 7 7 40 1.206E9 15.42 25.79 6 18 1997.74 28.94 7 22 349 37.3 4.32 HVO_A0406 conserved hypothetical protein 28.89 1 1 8 28 6.708E8 15.83 28.89 8 14 1329.97 28.89 8 14 405 44.4 5.30 HVO_1878 NAD synthase 28.62 1 6 6 14 3.311E8 6.89 19.57 5 6 586.66 28.62 6 8 276 29.6 4.37 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 28.57 1 7 7 29 2.874E8 21.01 28.57 7 15 1402.91 28.57 7 14 364 39.3 4.35 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 28.57 1 3 3 8 8.243E7 2.48 20.88 2 3 370.59 28.57 3 5 91 10.4 4.07 HVO_0049 argininosuccinate synthase 28.15 1 10 10 44 2.722E9 35.70 28.15 10 23 2201.61 26.17 9 21 405 44.5 4.34 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 27.98 1 5 5 11 3.809E8 5.49 27.98 5 7 226.00 14.77 3 4 386 42.1 4.49 HVO_1338 replication protein A 27.87 1 8 8 25 6.403E8 18.31 27.87 8 13 1304.42 22.72 7 12 427 46.0 4.36 HVO_1572 DNA gyrase subunit B 27.86 1 12 13 37 4.825E8 19.98 21.91 11 19 1354.24 25.51 12 18 639 71.2 4.83 HVO_0549 2-keto-3-deoxygluconate kinase 27.81 1 7 8 28 3.581E8 13.14 24.06 7 14 1128.63 25.94 7 14 320 34.1 4.34 HVO_0792 3-dehydroquinate synthase type II 27.81 1 10 10 46 1.376E9 45.03 27.81 10 23 2927.29 27.81 10 23 392 43.1 4.44 HVO_1087 UspA domain protein 27.66 1 4 4 9 1.550E8 5.19 27.66 4 4 561.70 27.66 4 5 141 15.2 4.98 HVO_2706 translation initiation factor aIF-2B delta subunit 27.66 1 4 4 20 6.916E8 16.66 27.66 4 10 818.86 27.66 4 10 282 30.7 4.42 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 27.62 1 6 6 38 4.595E8 26.01 27.62 6 18 1751.62 27.62 6 20 362 39.6 4.82 HVO_2700 AAA-type ATPase (CDC48 subfamily) 27.59 1 17 18 51 5.794E8 20.77 27.59 18 27 1779.30 23.34 15 24 754 82.8 4.75 HVO_2239 UspA domain protein 27.46 1 4 4 16 9.228E8 16.48 27.46 4 8 875.71 27.46 4 8 142 15.4 4.16 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 27.42 1 6 6 15 1.458E8 10.11 27.42 6 8 574.49 21.67 5 7 383 42.0 4.49 HVO_2675 histidinol dehydrogenase 27.34 1 6 6 18 2.938E8 9.82 25.00 5 9 846.33 27.34 6 9 428 45.4 4.50 HVO_1370 gamma-glutamyl phosphate reductase 27.25 1 9 9 38 1.316E9 33.11 27.25 9 19 2047.46 27.25 9 19 444 48.1 4.34 HVO_2188 phosphoribosylformylglycinamidine synthase 1 27.23 1 5 5 14 3.449E8 7.77 27.23 5 7 621.61 27.23 5 7 224 23.9 4.36 HVO_1299 HTH domain protein 27.17 1 4 4 7 1.166E8 0.00 19.08 3 3 302.93 27.17 4 4 173 18.9 4.84 HVO_0467 PhoU/TrkA-C domain protein 27.11 1 8 8 29 4.252E8 22.15 27.11 8 15 1355.32 23.38 7 14 402 43.3 4.49 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 27.11 1 12 12 30 7.735E8 13.69 21.91 10 14 1270.10 27.11 12 16 461 50.7 4.73 HVO_0511 NAD-dependent epimerase/dehydratase 27.10 1 5 5 18 2.049E8 7.20 27.10 5 9 737.38 27.10 5 9 262 29.3 4.78 HVO_0694 probable phosphoribosyltransferase 27.00 1 6 6 20 6.730E7 9.65 27.00 6 10 989.88 27.00 6 10 237 27.0 4.32 HVO_0415 repair helicase 26.95 1 12 12 49 1.232E9 33.17 21.43 9 23 2518.94 24.03 11 26 616 69.6 4.70 HVO_B0061 precorrin-2 C20-methyltransferase 26.81 1 4 4 14 2.506E8 8.81 19.15 3 6 669.26 26.81 4 8 235 25.3 4.63 HVO_0573 endonuclease IV 26.80 1 5 5 21 9.388E8 5.55 20.27 4 10 887.61 26.80 5 11 291 31.4 4.44 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 26.75 1 7 7 37 8.493E8 21.17 26.75 7 19 1323.52 26.75 7 18 415 44.4 4.41 HVO_1175 DUF2110 family protein 26.67 1 4 4 28 1.462E9 25.60 26.67 4 14 1608.62 26.67 4 14 225 24.4 4.63 HVO_2496 adenylate kinase 26.44 1 5 5 28 1.953E9 27.76 26.44 5 13 1795.47 26.44 5 15 208 23.1 4.25 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 26.43 1 7 7 31 2.327E8 28.85 26.43 7 16 1556.03 26.43 7 15 454 48.5 4.46 HVO_0041 ornithine carbamoyltransferase 26.42 1 5 5 15 4.960E8 10.22 26.42 5 8 634.69 26.42 5 7 299 32.7 4.37 HVO_0874 beta-lactamase domain protein 26.41 1 14 14 71 2.193E9 62.01 26.41 14 35 4500.27 26.41 14 36 640 71.9 5.14 HVO_0812 phosphoenolpyruvate synthase 26.15 1 18 18 54 4.786E8 34.29 23.52 16 26 2621.84 21.29 16 28 761 83.1 4.63 HVO_2756 50S ribosomal protein L10 26.15 1 6 6 49 1.221E9 45.59 26.15 6 25 2850.26 26.15 6 24 348 36.9 3.99 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 11 1.079E8 7.47 26.15 3 6 510.05 26.15 3 5 130 13.4 8.56 HVO_0429 archaemetzincin 26.01 1 2 2 3 1.157E8 156.40 26.01 2 3 173 19.3 6.54 HVO_1577 conserved hypothetical protein 25.99 1 4 4 15 7.594E8 7.40 25.99 4 7 664.38 25.99 4 8 177 19.4 4.74 HVO_2721 amidophosphoribosyltransferase 25.96 1 7 7 28 1.541E9 17.45 25.96 7 14 1002.88 25.96 7 14 493 53.4 4.78 HVO_1527 glucose-1-phosphate uridylyltransferase 25.93 1 6 6 25 4.602E8 15.03 25.93 6 13 1228.34 23.46 5 12 243 27.5 4.70 HVO_0233 ribose-phosphate pyrophosphokinase 25.80 1 4 4 14 4.491E8 6.80 25.80 4 7 480.03 25.80 4 7 283 29.6 4.40 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 25.79 1 9 9 38 4.279E8 23.65 25.79 9 19 1548.27 25.79 9 19 473 50.8 4.58 HVO_B0059 cobalt-precorrin 5A hydrolase 25.77 1 5 5 18 1.877E8 16.46 25.77 5 9 880.62 25.77 5 9 326 34.5 4.51 HVO_1871 UPF0447 family protein 25.75 1 10 10 47 1.033E9 33.69 22.36 9 23 2336.46 25.75 10 24 501 56.1 4.59 HVO_2726 glutamate--tRNA ligase 25.64 1 10 10 44 4.518E8 26.71 25.64 10 22 2167.85 25.64 10 22 585 65.2 4.58 40354192 keratin 10 [Homo sapiens] 25.51 1 0 14 47 3.460E8 35.75 24.32 13 24 2434.38 22.26 13 23 584 58.8 5.16 HVO_0788 tryptophan synthase beta subunit 25.36 1 8 8 33 6.645E8 30.60 23.70 7 15 2051.77 25.36 8 18 422 45.7 4.65 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 25.13 1 0 14 47 3.460E8 35.75 23.95 13 24 2434.38 21.92 13 23 593 59.5 5.21 >sp|TRYP_PIG| 25.11 1 4 4 110 3.833E10 132.29 25.11 4 54 9279.43 25.11 4 56 231 24.4 7.18 HVO_0466 citrate (si)-synthase 25.07 1 9 9 55 2.496E9 56.05 22.16 7 25 3873.05 25.07 9 30 379 41.8 4.55 HVO_0138 tyrosine--tRNA ligase 25.00 1 7 7 34 1.052E9 16.49 25.00 7 17 1470.03 18.60 6 17 328 36.1 4.34 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 24.93 1 9 9 59 3.744E9 51.47 24.93 8 29 3427.15 24.93 9 30 357 40.3 4.40 HVO_0349 DNA-directed RNA polymerase subunit A' 24.90 1 20 20 94 1.379E9 77.21 22.03 18 45 5879.16 24.90 20 49 976 108.8 4.81 HVO_2454 anthranilate synthase component I 24.81 1 10 10 34 8.189E8 19.66 24.81 10 17 1530.15 24.81 10 17 524 55.9 4.56 7428712 "keratin 1, type II, cytoskeletal - human" 24.73 1 0 18 104 1.603E9 87.04 24.73 18 51 6445.81 24.73 18 53 643 65.5 6.35 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 24.60 1 5 5 26 2.384E9 30.12 24.60 5 13 2292.59 24.60 5 13 252 26.0 4.39 HVO_1025 acetyl-CoA C-acyltransferase 24.54 1 6 6 28 8.039E8 21.92 24.54 6 13 1488.98 24.54 6 15 383 40.7 4.56 HVO_0206 alanine--tRNA ligase 24.51 1 19 19 64 4.983E8 48.70 22.45 17 30 3428.87 23.43 18 34 922 102.4 4.54 HVO_1187 conserved hypothetical protein 24.48 1 3 3 9 9.217E7 6.36 24.48 3 5 380.01 24.48 3 4 143 16.4 4.86 HVO_1866 uridylate kinase 24.47 1 4 4 22 7.306E8 19.39 24.47 4 11 1074.66 24.47 4 11 237 24.6 4.42 HVO_0046 putative glutamate--argW ligase 24.40 1 5 5 27 5.859E8 27.21 24.40 5 13 1638.84 24.40 5 14 291 31.9 4.87 HVO_0787 indole-3-glycerol-phosphate synthase 24.30 1 4 4 12 2.656E8 5.38 24.30 4 6 478.25 24.30 4 6 251 26.7 4.44 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 24.21 1 7 7 28 7.141E8 17.85 24.21 7 14 1163.18 24.21 7 14 347 36.8 4.93 HVO_2168 AAA-type ATPase (MoxR subfamily) 24.01 1 6 6 15 2.082E8 5.72 20.06 5 7 563.92 24.01 6 8 329 35.9 4.54 HVO_0388 homolog to ribonuclease R 23.69 1 10 10 31 3.205E8 25.84 17.77 9 15 1659.13 23.69 10 16 439 50.3 4.73 HVO_1076 sugar nucleotidyltransferase 23.60 1 6 6 33 1.649E9 29.46 23.60 6 17 1973.80 21.74 5 16 322 35.8 4.20 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 23.55 1 5 5 12 5.544E7 11.23 23.55 5 6 489.91 23.55 5 6 327 36.2 4.63 HVO_2912 ThiJ/PfpI domain protein 23.38 1 2 2 6 9.038E7 2.36 23.38 2 3 275.39 23.38 2 3 201 20.9 4.36 HVO_0699 translation initiation factor aIF-2 alpha subunit 23.31 1 6 6 24 4.702E8 19.64 23.31 6 12 1257.76 23.31 6 12 266 29.5 4.46 HVO_A0432 conserved hypothetical protein 23.21 1 0 7 20 3.682E8 13.58 23.21 7 10 1115.80 23.21 7 10 405 44.5 5.24 HVO_0601 homoserine dehydrogenase 23.10 1 5 6 30 4.853E8 24.25 23.10 6 16 1696.50 21.20 5 14 316 32.2 4.25 HVO_1018 RecJ domain protein 22.75 1 13 13 57 1.174E9 47.35 22.75 13 30 3422.70 21.96 12 27 633 69.8 4.58 HVO_1575 arginase 22.74 1 4 4 16 2.420E8 7.19 22.74 4 8 342.26 22.74 4 8 299 31.0 4.58 HVO_1778 catalase-peroxidase 22.70 1 11 11 76 2.189E9 59.44 22.70 11 38 4377.17 22.70 11 38 718 80.0 4.31 HVO_1459 ThuA family protein 22.69 1 3 3 16 6.721E8 16.66 22.69 3 8 1101.68 22.69 3 8 238 26.8 4.67 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 22.67 1 13 13 61 9.836E8 37.55 19.37 11 27 3357.06 22.67 13 34 697 74.5 4.13 HVO_2536 CHP00300 family protein 22.60 1 4 4 14 4.867E8 0.00 22.60 4 7 237.23 22.60 4 7 416 44.8 4.51 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 22.59 1 4 4 15 3.272E8 20.08 22.59 4 8 1060.63 18.89 3 7 270 29.1 4.35 HVO_1957 proteasome-activating nucleotidase 22.57 1 6 7 17 1.703E8 7.73 20.39 6 8 618.26 19.66 6 9 412 45.6 4.48 HVO_1412 diphosphomevalonate decarboxylase 22.53 1 8 8 28 1.518E9 17.36 22.53 8 14 1343.94 22.53 8 14 324 35.4 4.78 HVO_A0496 UspA domain protein 22.41 1 6 6 22 9.377E8 7.82 22.41 6 11 637.85 22.41 6 11 290 31.4 4.60 HVO_1965 rRNA maturation endonuclease Nob1 22.37 1 2 2 2 3.330E7 0.00 22.37 2 2 152 16.8 4.70 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 22.36 1 3 3 4 2.439E7 0.00 10.97 2 2 156.04 15.61 2 2 237 26.2 4.70 HVO_1823 UspA domain protein 22.22 1 3 3 12 2.815E8 14.13 22.22 3 6 728.73 22.22 3 6 153 16.4 4.60 HVO_1880 conserved hypothetical protein 22.22 1 4 4 16 7.103E7 7.96 22.22 4 8 875.59 22.22 4 8 225 23.8 4.59 HVO_2793 conserved hypothetical protein 22.22 1 3 3 5 7.129E7 0.00 17.06 2 2 152.85 22.22 3 3 252 27.1 4.46 HVO_B0352 cupin 2 barrel domain protein 22.22 1 2 2 3 3.125E7 279.03 22.22 2 3 117 12.3 4.30 HVO_0829 peptidase S9 family protein 22.20 1 8 8 32 2.956E8 24.64 22.20 8 17 1852.75 16.45 7 15 608 67.4 4.54 HVO_1567 conserved hypothetical protein 22.13 1 4 4 8 2.491E8 4.52 22.13 4 4 326.45 22.13 4 4 235 25.7 4.36 HVO_2781 DNA-directed RNA polymerase subunit D 22.01 1 4 4 36 1.859E9 27.60 22.01 4 18 2366.79 22.01 4 18 259 28.1 4.32 HVO_2313 siroheme decarboxylase AhbB 21.81 1 3 3 8 4.981E8 5.66 21.81 3 4 358.22 21.81 3 4 353 39.6 4.64 HVO_2060 NUDIX family hydrolase 21.79 1 3 3 6 2.201E8 1.93 21.79 3 3 182.95 21.79 3 3 156 17.7 4.41 HVO_1478 transcription initiation factor TFB 21.77 1 4 7 33 1.146E9 25.55 21.77 7 16 2265.85 21.77 7 17 317 35.7 5.47 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 21.72 1 3 4 16 4.029E8 15.08 21.72 4 8 923.10 21.72 4 8 267 29.1 4.63 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 21.71 1 5 5 16 2.005E8 4.65 21.71 5 8 648.04 21.71 5 8 327 36.0 4.73 HVO_A0458 ParA domain protein 21.65 1 4 4 12 2.025E8 9.06 21.65 4 6 608.37 21.65 4 6 291 32.2 4.79 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 21.62 1 6 6 15 1.637E8 13.78 21.62 6 7 1012.81 21.62 6 8 333 36.7 4.56 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 21.62 1 8 8 57 1.714E9 42.53 21.62 8 28 3211.46 21.62 8 29 370 41.9 4.48 HVO_0122 phosphoglycerate dehydrogenase 21.60 1 5 5 15 4.359E7 11.07 14.51 4 7 629.80 21.60 5 8 324 35.3 5.35 HVO_2716 acyl-CoA dehydrogenase 21.52 1 5 5 25 2.963E8 29.30 21.52 5 13 1493.20 21.52 5 12 381 41.3 4.65 HVO_1164 HD family hydrolase 21.48 1 5 5 16 4.899E8 10.03 21.48 5 8 814.13 21.48 5 8 270 29.8 4.87 HVO_A0307 Lrp/AsnC family transcription regulator 21.47 1 3 3 10 1.055E8 6.25 21.47 3 5 506.31 21.47 3 5 177 19.4 4.39 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 21.45 1 6 6 20 1.059E9 8.74 21.45 6 9 1066.11 21.45 6 11 373 40.2 4.44 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 21.34 1 4 4 9 5.680E8 3.22 11.07 2 3 399.20 21.34 4 6 253 26.0 4.60 HVO_2008 archaeosine synthase 21.20 1 8 8 22 5.815E8 10.38 21.20 8 11 857.83 18.46 7 11 585 64.9 4.81 HVO_0712 shikimate dehydrogenase (nonfunctional) 21.19 1 2 2 2 8.012E7 0.00 21.19 2 2 269 27.7 4.65 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 21.13 1 3 3 16 3.650E8 15.23 21.13 3 8 1089.52 21.13 3 8 336 36.0 4.51 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 21.09 1 2 2 9 7.561E7 9.58 21.09 2 5 454.64 21.09 2 4 128 13.0 4.31 HVO_1854 histidine--tRNA ligase 20.88 1 8 8 40 1.409E9 25.57 20.88 8 20 2135.71 20.88 8 20 431 47.1 4.37 HVO_1446 "fructose-1,6-bisphosphatase" 20.88 1 3 3 7 6.839E7 2.71 12.79 2 3 255.57 20.88 3 4 297 31.6 4.45 HVO_1374 acyl-CoA synthetase 20.80 1 8 8 25 1.096E9 22.37 14.83 7 12 1424.92 20.80 8 13 553 61.1 4.50 HVO_2156 UspA domain protein 20.60 1 5 5 19 8.080E8 7.11 20.60 5 9 771.59 20.60 5 10 301 31.6 4.69 HVO_0541 aconitate hydratase 20.58 1 14 14 45 2.395E9 16.34 15.35 11 20 1708.92 18.98 12 25 938 102.1 4.40 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 20.51 1 8 8 27 1.701E8 28.10 20.51 8 14 1427.59 18.55 7 13 512 53.8 4.78 HVO_1048 phosphoribosylformylglycinamidine synthase 2 20.51 1 8 8 38 4.683E8 49.02 19.52 7 19 2666.58 15.81 7 19 702 72.9 4.18 HVO_0519 replication protein A 20.50 1 8 8 45 6.266E8 28.34 20.50 8 21 2197.01 20.50 8 24 483 51.0 4.13 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 20.38 1 4 4 14 1.470E8 14.04 20.38 4 7 840.13 20.38 4 7 265 29.3 4.92 HVO_2425 GNAT family acetyltransferase 20.37 1 4 4 10 7.668E8 2.52 20.37 4 5 299.37 20.37 4 5 216 24.4 4.54 HVO_0214 L-lactate dehydrogenase 20.31 1 7 7 43 2.241E9 32.49 18.44 6 21 2657.13 20.31 7 22 320 34.5 4.49 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 20.31 1 6 6 31 1.216E9 34.51 17.22 5 15 2120.64 20.31 6 16 453 47.5 4.63 HVO_1571 DNA topoisomerase VI subunit B 20.05 1 10 10 36 5.283E8 19.83 16.42 8 16 2087.14 20.05 10 20 798 87.4 4.73 HVO_1510 2-isopropylmalate synthase 20.00 1 6 6 24 1.582E9 21.15 20.00 6 12 1463.74 18.64 5 12 440 47.7 4.82 HVO_2481 HD family hydrolase 19.74 1 4 4 10 1.158E8 0.00 19.74 4 5 252.56 19.74 4 5 390 42.7 6.14 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 19.70 1 19 19 52 5.608E8 30.08 17.21 16 25 2266.05 17.60 17 27 1284 141.2 4.35 HVO_1020 HEAT-PBS family protein 19.57 1 6 6 26 1.909E8 25.31 19.57 6 13 1604.14 19.57 6 13 419 45.5 3.95 HVO_2708 YfiH family protein 19.57 1 3 3 15 1.900E8 12.06 19.57 3 8 792.20 19.57 3 7 322 35.4 4.35 HVO_A0133 conserved hypothetical protein 19.52 1 4 4 10 2.328E8 5.83 19.52 4 5 488.55 19.52 4 5 292 30.8 5.17 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 19.51 1 7 7 26 4.214E8 21.40 19.51 7 13 1185.86 19.51 7 13 615 67.6 4.88 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 19.44 1 5 5 21 4.719E8 13.00 19.44 5 10 986.67 19.44 5 11 427 45.4 4.56 HVO_1610 conserved hypothetical protein 19.43 1 2 2 3 6.993E7 201.91 19.43 2 3 283 30.5 4.55 HVO_2690 GFO family oxidoreductase 19.40 1 6 6 18 4.187E8 14.12 17.49 5 9 829.49 19.40 6 9 366 40.0 4.60 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 24 1.826E9 14.44 19.31 5 11 1380.87 19.31 5 13 378 39.7 4.67 HVO_0017 conserved hypothetical protein 19.27 1 3 3 12 5.549E8 9.64 19.27 3 6 741.46 19.27 3 6 192 21.9 4.50 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 19.14 1 3 3 15 2.970E8 9.37 19.14 3 8 828.04 19.14 3 7 324 33.6 3.99 HVO_1289 OsmC domain protein 18.94 1 2 2 10 1.134E9 12.88 18.94 2 5 886.27 18.94 2 5 132 14.2 3.85 HVO_0697 PAC2 family protein 18.82 1 2 2 16 5.849E8 18.13 18.82 2 8 905.24 18.82 2 8 255 27.4 4.08 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 18.69 1 4 4 11 8.344E7 4.39 16.39 3 5 277.24 18.69 4 6 305 32.7 4.56 HVO_1654 cysteine synthase 18.63 1 4 4 12 5.279E8 8.28 18.63 4 6 558.18 18.63 4 6 306 32.3 4.32 HVO_2256 DUF262 family protein 18.61 1 9 9 30 3.286E8 21.25 17.10 8 14 1381.17 18.61 9 16 462 54.9 4.89 HVO_0916 diphthine synthase 18.59 1 3 3 10 2.834E8 6.46 18.59 3 5 380.74 18.59 3 5 269 29.1 4.54 HVO_1660 DisA-N domain protein 18.59 1 4 4 18 8.336E8 17.38 18.59 4 9 1077.58 18.59 4 9 269 28.9 4.73 HVO_2717 alanine--tRNA ligase 18.59 1 6 6 21 1.528E8 14.08 15.58 5 10 1079.96 18.59 6 11 398 41.6 4.39 HVO_2707 GFO family oxidoreductase 18.55 1 5 5 20 5.198E8 16.57 18.55 5 10 966.41 18.55 5 10 372 41.0 4.55 HVO_2763 homolog to ribonuclease Z 18.55 1 4 4 14 1.797E8 9.44 16.13 3 7 633.45 18.55 4 7 248 26.6 4.53 HVO_B0018 ParA domain protein 18.47 1 3 3 11 1.622E8 8.80 18.47 3 6 401.40 18.47 3 5 287 31.7 4.74 HVO_A0388 Lrp/AsnC family transcription regulator 18.39 1 3 3 7 1.754E8 0.00 18.39 3 4 109.57 18.39 3 3 174 20.1 4.86 HVO_2960 dihydrolipoamide S-acyltransferase 18.23 1 7 7 23 1.735E8 15.93 18.23 7 12 1209.89 18.23 7 11 521 54.9 4.40 HVO_B0055 conserved hypothetical protein 18.22 1 3 3 6 6.432E7 3.63 18.22 3 3 267.82 18.22 3 3 225 23.9 4.69 HVO_0484 50S ribosomal protein L10e 18.18 1 2 2 4 0.000E0 2.19 18.18 2 2 163.34 18.18 2 2 176 19.8 8.72 HVO_1287 PfpI family protease 18.18 1 2 2 20 1.608E8 5.88 18.18 2 10 616.53 18.18 2 10 198 21.5 4.53 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 18.06 1 7 8 22 9.755E8 10.39 15.78 5 10 966.06 16.35 7 12 526 57.2 4.31 HVO_2948 phenylalanine--tRNA ligase alpha subunit 18.04 1 5 5 32 5.520E8 25.86 18.04 5 16 1696.67 18.04 5 16 499 55.1 4.41 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 18.02 1 5 5 12 1.124E8 4.15 14.83 4 5 592.11 18.02 5 7 344 39.1 4.73 HVO_2548 50S ribosomal protein L6 17.98 1 2 2 6 6.136E7 6.45 17.98 2 3 287.21 17.98 2 3 178 19.6 4.68 HVO_1809 isochorismatase family protein 17.89 1 3 3 3 3.601E7 156.63 17.89 3 3 190 21.0 4.55 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 17.84 1 3 3 14 5.255E8 10.17 17.84 3 7 753.23 17.84 3 7 269 28.3 4.49 HVO_2614 uridine phosphorylase 17.77 1 3 3 26 1.625E9 21.02 17.77 3 13 1288.80 17.77 3 13 242 25.8 4.30 HVO_2879 ornithine cyclodeaminase 17.77 1 4 4 8 3.140E8 0.00 7.53 2 3 275.99 17.77 4 5 332 34.6 4.45 HVO_2945 valine--tRNA ligase 17.70 1 13 13 47 1.214E9 25.78 14.60 10 21 2562.97 17.70 13 26 870 98.9 4.36 HVO_2965 phosphoserine phosphatase 17.67 1 2 2 2 3.579E7 1.72 17.67 2 2 215 23.2 4.51 HVO_1867 lysine--tRNA ligase 17.66 1 7 7 21 3.797E8 10.30 11.53 6 10 777.99 16.22 6 11 555 62.1 4.46 HVO_2435 peptidase M24 family protein 17.66 1 5 5 12 2.091E8 11.60 14.40 4 6 798.07 14.40 4 6 368 40.0 4.53 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 17.65 1 4 4 20 3.805E8 5.30 17.65 4 10 910.46 17.65 4 10 357 39.8 4.41 HVO_2227 siroheme decarboxylase AhbA 17.58 1 3 3 10 4.678E7 5.36 11.24 2 4 268.99 17.58 3 6 347 39.1 4.69 HVO_1134 conserved hypothetical protein 17.57 1 9 9 39 3.833E8 27.99 16.25 8 18 1770.97 17.57 9 21 757 80.6 4.35 HVO_1387 enoyl-CoA hydratase 17.51 1 4 4 22 3.332E8 9.70 17.51 4 11 1054.38 17.51 4 11 257 27.5 4.51 HVO_1148 30S ribosomal protein S15 17.42 1 2 2 2 1.645E8 172.73 17.42 2 2 155 17.5 4.91 HVO_A0331 D-galactonate dehydratase 17.19 1 3 3 9 1.798E8 2.53 13.80 2 4 335.24 17.19 3 5 384 42.8 4.83 HVO_0100 NMD3 family protein 17.07 1 4 4 9 1.285E8 2.00 17.07 4 4 271.99 17.07 4 5 375 41.6 4.46 HVO_1508 acetolactate synthase large subunit 17.04 1 6 6 15 2.906E8 13.75 12.61 5 7 798.23 17.04 6 8 587 62.3 4.36 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 16.97 1 3 3 9 2.230E8 3.04 9.39 2 4 383.96 16.97 3 5 277 30.6 4.30 HVO_2205 arNOG06768 family NADH-binding domain protein 16.94 1 4 4 18 7.477E7 18.68 16.94 4 9 1064.93 16.94 4 9 301 32.0 5.00 HVO_1550 acyl-CoA thioester hydrolase 16.88 1 2 2 12 2.833E8 12.84 16.88 2 6 741.94 16.88 2 6 160 17.6 4.55 HVO_A0266 IclR family transcription regulator 16.86 1 3 3 12 1.479E8 18.24 16.86 3 6 953.67 16.86 3 6 255 27.7 6.05 HVO_0997 peptidase M24 family protein 16.85 1 3 3 10 6.731E7 6.79 16.85 3 4 498.75 16.85 3 6 368 39.9 4.49 HVO_0044 acetylglutamate kinase 16.82 1 4 4 18 2.538E8 15.26 16.82 4 9 981.21 16.82 4 9 327 33.2 4.49 HVO_2507 Lrp/AsnC family transcription regulator 16.79 1 3 3 7 6.774E7 4.15 16.79 3 4 253.44 10.22 2 3 137 15.5 4.67 HVO_1496 phosphotransferase system component I 16.64 1 8 8 33 2.832E8 20.41 16.64 8 16 1531.12 16.64 8 17 565 60.3 4.21 HVO_B0382 TATA-binding transcription initiation factor 16.49 1 2 2 14 2.499E8 14.90 16.49 2 7 706.99 16.49 2 7 188 20.1 4.12 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 16.47 1 0 2 4 5.819E8 0.00 16.47 2 2 165.63 16.47 2 2 85 10.0 5.94 HVO_A0636 YbaK domain protein 16.46 1 2 2 14 1.262E8 11.27 16.46 2 7 716.70 16.46 2 7 158 16.7 4.54 HVO_0402 DUF124 family protein 16.44 1 2 2 10 9.092E8 2.86 16.44 2 5 338.82 16.44 2 5 225 24.0 4.58 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 16.40 1 3 3 9 1.476E8 4.45 9.52 2 4 477.97 16.40 3 5 189 21.7 4.46 HVO_1344 SBDS family protein 16.39 1 3 3 8 5.356E7 1.70 16.39 3 4 342.23 16.39 3 4 238 26.5 4.51 HVO_1847 oligoendopeptidase PepF 16.36 1 8 8 17 3.279E8 9.51 16.36 8 9 791.35 15.03 7 8 599 68.5 4.41 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 16.33 1 6 6 26 7.254E8 19.39 16.33 6 12 1448.43 16.33 6 14 447 48.5 4.56 HVO_B0371 aldehyde dehydrogenase 16.33 1 5 5 13 1.353E8 13.76 16.33 5 7 820.61 16.33 5 6 496 52.5 4.39 HVO_1531 UDP-glucose 6-dehydrogenase 16.28 1 6 6 19 4.421E8 7.99 14.19 5 9 806.25 16.28 6 10 430 45.9 4.50 HVO_0970 ribulose-bisphosphate carboxylase large subunit 16.18 1 6 6 28 3.839E8 20.79 16.18 6 14 1416.82 16.18 6 14 414 43.9 4.59 HVO_2639 DUF1611 family protein 16.13 1 5 5 15 1.244E8 8.60 12.61 4 7 639.17 16.13 5 8 341 36.3 4.44 HVO_A0418 conserved hypothetical protein 16.13 1 2 2 3 9.831E6 335.56 16.13 2 3 155 17.9 4.67 HVO_2338 homoserine kinase 16.04 1 2 2 4 3.379E8 0.00 16.04 2 2 99.42 16.04 2 2 293 29.8 4.88 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 16.02 1 3 3 14 1.332E8 11.77 16.02 3 7 728.77 16.02 3 7 231 25.0 4.25 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 15.90 1 12 12 34 3.348E8 29.60 12.94 10 16 2390.15 13.12 10 18 1082 117.2 4.32 HVO_0572 lipoate-protein ligase 15.64 1 3 4 9 1.276E8 5.79 13.09 3 4 464.86 15.64 4 5 275 30.5 4.84 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 15.52 1 5 5 9 1.174E8 5.09 15.52 5 5 312.67 12.32 4 4 406 45.5 5.08 HVO_1295 histidinol-phosphate aminotransferase 15.51 1 4 4 11 1.064E8 12.86 11.63 3 5 659.88 15.51 4 6 361 39.4 4.51 HVO_0054 glycine--tRNA ligase 15.49 1 6 6 23 2.745E9 24.31 13.13 5 11 1878.17 15.49 6 12 594 64.9 4.21 HVO_A0350 conserved hypothetical protein 15.49 1 3 3 8 2.403E7 6.42 15.49 3 4 506.54 15.49 3 4 213 23.8 9.64 HVO_1623 conserved hypothetical protein 15.44 1 4 4 16 2.456E8 8.67 15.44 4 8 756.05 15.44 4 8 298 32.8 4.56 HVO_0158 TATA-binding transcription initiation factor 15.34 1 2 3 9 8.033E8 3.78 15.34 3 5 375.47 11.64 2 4 189 20.3 4.22 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 15.31 1 3 3 17 1.499E8 12.65 15.31 3 9 676.77 15.31 3 8 294 32.5 4.75 HVO_2333 conserved hypothetical protein 15.26 1 4 4 7 1.869E8 2.80 15.26 4 4 273.15 12.99 3 3 308 34.9 4.54 HVO_1391 NUDIX family hydrolase 15.23 1 2 2 6 3.388E7 0.00 15.23 2 3 229.70 15.23 2 3 151 17.4 5.01 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 15.16 1 5 5 9 8.236E7 5.25 11.09 4 4 345.01 15.16 5 5 442 46.9 4.58 HVO_2456 anthranilate phosphoribosyltransferase 15.11 1 2 3 7 2.515E8 1.79 15.11 3 4 200.65 11.18 2 3 331 33.8 4.35 HVO_2581 quinolinate synthase A 15.06 1 5 5 10 2.145E8 3.77 15.06 5 5 420.23 15.06 5 5 385 42.0 4.41 HVO_1236 acyl-CoA synthetase 14.77 1 5 5 12 3.530E8 3.64 11.40 4 6 367.34 14.77 5 6 535 59.1 4.60 HVO_1918 probable metallo-beta-lactamase family hydrolase 14.57 1 2 2 7 1.010E8 0.00 14.57 2 5 60.33 14.57 2 2 302 34.0 4.55 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 14.53 1 4 4 8 3.858E7 5.52 8.43 2 3 404.08 14.53 4 5 344 37.0 4.55 HVO_2908 dihydropteroate synthase 14.51 1 4 4 10 7.496E7 8.00 14.51 4 5 346.28 14.51 4 5 379 40.8 4.53 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 14.43 1 2 2 2 1.246E8 142.75 14.43 2 2 97 10.8 4.53 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 14.29 1 3 3 10 5.050E8 2.20 14.29 3 5 332.36 14.29 3 5 238 24.7 4.15 HVO_1348 probable YjeF family carbohydrate kinase 14.23 1 4 4 14 1.531E8 16.22 14.23 4 7 705.40 14.23 4 7 478 48.8 4.45 HVO_2702 alpha/beta hydrolase fold protein 14.23 1 3 3 8 5.604E7 5.77 14.23 3 4 292.12 14.23 3 4 260 28.0 4.53 HVO_2761 mevalonate kinase 14.17 1 3 3 8 5.796E7 1.75 14.17 3 4 322.11 14.17 3 4 367 38.2 4.31 HVO_B0331 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 14.16 1 2 2 2 0.000E0 43.85 14.16 2 2 353 39.0 4.77 HVO_1235 creatininase 14.02 1 3 3 13 7.966E7 2.56 10.61 2 6 498.97 14.02 3 7 264 29.2 4.84 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 13.99 1 5 5 11 1.459E8 5.69 9.90 3 4 397.00 13.99 5 7 586 63.4 4.70 HVO_1816 dihydroorotase 13.99 1 5 5 13 1.447E8 10.57 13.99 5 7 558.76 9.09 3 6 429 45.4 4.40 HVO_2712 3'-5' RNA ligase 13.99 1 4 4 6 7.932E7 3.94 12.35 3 3 229.90 12.14 3 3 486 53.4 4.92 HVO_2759 peptidase M42 family protein 13.84 1 4 5 14 5.959E8 6.09 13.84 5 7 612.71 13.84 5 7 354 37.0 4.40 HVO_0234 conserved hypothetical protein 13.82 1 2 2 6 2.558E7 5.28 13.82 2 3 233.56 13.82 2 3 275 28.1 4.48 HVO_2467 NADPH:quinone reductase 13.71 1 3 3 10 4.559E7 11.63 13.71 3 5 591.86 13.71 3 5 321 33.0 4.51 HVO_2947 phenylalanine--tRNA ligase beta subunit 13.68 1 7 7 29 9.417E8 11.01 11.75 6 14 1417.90 13.68 7 15 570 63.3 4.46 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 11 3.132E8 5.19 13.66 2 5 655.20 13.66 2 6 183 20.0 4.21 HVO_3014 origin-associated GTP-binding protein OapA 13.62 1 2 2 2 2.636E8 81.06 13.62 2 2 213 24.0 5.01 HVO_2373 30S ribosomal protein S8e 13.60 1 2 2 6 9.742E7 3.73 13.60 2 3 234.48 13.60 2 3 125 13.6 10.48 HVO_1491 HAD superfamily hydrolase 13.48 1 5 5 21 1.358E8 8.05 13.48 5 11 822.63 13.48 5 10 408 44.4 4.60 HVO_1380 methylmalonyl-CoA mutase subunit A 13.44 1 5 5 16 6.960E7 3.54 13.44 5 8 373.46 13.44 5 8 558 61.9 4.41 HVO_1804 nicotinate phosphoribosyltransferase 13.40 1 4 4 11 3.138E8 6.63 10.31 3 5 409.07 13.40 4 6 388 41.1 4.60 HVO_0431 HAD superfamily hydrolase 13.38 1 3 3 7 1.524E8 3.68 13.38 3 4 209.91 7.75 2 3 284 30.4 4.26 HVO_1547 isoleucine--tRNA ligase 13.33 1 9 9 45 6.839E8 41.62 13.33 9 23 2374.62 13.33 9 22 1043 117.9 4.30 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 13.27 1 3 3 8 1.300E8 3.54 13.27 3 4 311.14 13.27 3 4 422 43.6 4.72 HVO_2580 L-aspartate oxidase 13.22 1 4 4 14 5.864E7 14.48 13.22 4 7 959.69 13.22 4 7 537 55.8 4.63 HVO_1337 rpa-associated protein 13.16 1 7 7 23 7.880E8 14.79 10.43 5 10 1227.94 13.16 7 13 623 64.8 3.68 HVO_1937 "probable 5,10-methylenetetrahydrofolate reductase" 13.11 1 2 2 3 1.061E8 0.00 13.11 2 3 328 34.5 4.63 HVO_2108 IclR family transcription regulator 13.04 1 2 2 4 7.778E7 1.64 13.04 2 2 109.45 13.04 2 2 253 28.0 5.74 HVO_1371 glutamate 5-kinase 12.96 1 2 2 5 4.587E8 3.30 12.96 2 3 127.61 12.96 2 2 301 32.0 4.25 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 12.95 1 4 4 15 6.736E8 11.43 12.95 4 7 996.70 12.95 4 8 363 39.7 4.25 HVO_1079 sulfate adenylyltransferase small subunit 12.92 1 3 3 6 2.167E8 1.64 12.92 3 3 165.53 12.92 3 3 325 37.5 4.18 HVO_1895 KEOPS complex subunit Kae1/Bud32 12.86 1 4 4 11 5.707E8 4.88 12.86 4 6 444.52 9.06 3 5 552 59.0 5.07 HVO_1570 DNA topoisomerase VI subunit A 12.84 1 4 4 9 4.215E8 4.21 10.11 3 4 458.17 12.84 4 5 366 41.8 4.63 HVO_1698 CBS/parB domain protein 12.83 1 2 3 10 8.508E8 5.59 12.83 3 6 398.74 12.83 3 4 265 29.4 4.92 HVO_2072 S-layer glycoprotein 12.82 1 5 5 96 2.174E9 72.38 12.82 5 49 2515.13 12.82 5 47 827 85.1 3.65 HVO_1465 naphthoate synthase 12.79 1 3 3 8 2.586E8 9.39 12.79 3 4 367.60 12.79 3 4 305 33.9 4.83 HVO_0658 tRNA pseudouridine(13) synthase TruD 12.74 1 3 3 10 1.487E8 0.00 12.74 3 5 237.91 12.74 3 5 463 50.6 4.70 HVO_0681 DNA topoisomerase I 12.74 1 8 8 24 1.090E8 14.12 9.05 6 10 1371.74 12.74 8 14 840 93.6 4.58 HVO_2951 tryptophan--tRNA ligase 12.67 1 5 5 11 1.828E8 4.32 11.15 4 5 372.18 12.67 5 6 529 59.1 4.53 HVO_1268 conserved hypothetical protein 12.66 1 2 2 8 7.473E7 6.24 12.66 2 4 259.20 12.66 2 4 237 26.4 5.21 HVO_0889 FAD-dependent oxidoreductase 12.62 1 2 2 6 1.345E8 4.85 12.62 2 3 459.72 12.62 2 3 214 21.8 3.89 HVO_2306 receiver box response regulator 12.50 1 2 2 4 1.048E8 4.41 12.50 2 2 193.80 12.50 2 2 248 26.5 4.13 HVO_1683 4-alpha-glucanotransferase 12.50 1 5 5 15 1.110E8 3.98 12.50 5 8 526.57 12.50 5 7 496 56.3 4.45 HVO_1372 pyrroline-5-carboxylate reductase 12.45 1 3 3 8 2.171E8 9.55 12.45 3 4 599.40 12.45 3 4 257 26.8 4.01 HVO_A0551 acyl-CoA synthetase 12.45 1 4 4 13 1.440E8 2.25 12.45 4 6 436.29 12.45 4 7 538 59.6 4.65 HVO_2068 "FtsZ family protein, type III" 12.43 1 2 3 8 2.143E8 3.64 12.43 3 4 360.52 12.43 3 4 370 38.7 4.49 HVO_B0115 fumarylacetoacetase family protein 12.37 1 3 3 9 4.083E8 5.33 8.13 2 4 449.31 12.37 3 5 283 30.3 4.21 HVO_1824 conserved hypothetical protein 12.35 1 4 4 10 2.690E8 8.05 12.35 4 5 416.28 12.35 4 5 429 47.4 4.20 HVO_2547 50S ribosomal protein L32e 12.34 1 2 2 12 9.944E7 9.01 12.34 2 6 637.89 12.34 2 6 235 25.8 4.75 HVO_B0114 IclR family transcription regulator 12.30 1 3 3 10 1.328E8 5.78 12.30 3 5 594.23 12.30 3 5 252 28.4 5.44 HVO_2297 deoxyhypusine synthase 12.26 1 2 2 8 1.205E8 2.32 12.26 2 4 219.28 12.26 2 4 359 38.6 4.59 HVO_A0485 aminotransferase class V 12.25 1 3 3 10 1.213E8 5.21 12.25 3 5 538.72 12.25 3 5 351 37.3 4.26 HVO_0087 porphobilinogen synthase 12.23 1 3 3 11 2.171E8 3.94 9.17 2 5 403.55 12.23 3 6 327 35.3 4.72 HVO_1327 AAA-type ATPase (CDC48 subfamily) 12.23 1 4 5 11 3.311E8 6.91 10.19 4 5 495.99 12.23 5 6 736 78.1 4.88 HVO_0552 DNA mismatch repair protein MutS 12.12 1 8 8 24 3.565E8 8.63 9.31 6 11 789.79 12.12 8 13 924 99.2 4.65 HVO_C0067 FAD-dependent oxidoreductase 12.12 1 3 3 10 6.916E7 11.76 12.12 3 5 625.31 12.12 3 5 396 42.7 4.30 HVO_1879 enoyl-CoA hydratase 12.12 1 3 3 5 2.175E7 397.00 12.12 3 5 231 24.3 5.21 HVO_1098 diaminopimelate decarboxylase 12.05 1 5 5 11 2.575E8 7.87 12.05 5 6 420.79 10.36 4 5 415 44.4 5.02 HVO_2784 30S ribosomal protein S13 11.98 1 2 2 6 3.731E8 3.90 11.98 2 3 221.74 11.98 2 3 167 18.9 5.17 HVO_1979 tRNA pseudouridine synthase Pus10 11.94 1 4 4 10 8.477E8 10.18 10.30 3 5 758.99 6.79 3 5 427 46.9 4.39 HVO_2648 phosphoglycerate dehydrogenase 11.91 1 3 3 8 1.897E8 4.13 11.91 3 4 311.51 11.91 3 4 319 34.2 4.64 HVO_1967 glucose-6-phosphate isomerase 11.86 1 3 3 6 2.038E8 3.90 7.44 2 3 245.57 7.91 2 3 430 45.6 4.40 HVO_2662 homolog to lactoylglutathione lyase 11.85 1 3 3 9 3.161E7 4.47 11.85 3 5 305.05 11.85 3 4 329 36.5 4.48 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 11.82 1 5 5 16 1.429E8 7.70 9.93 4 7 779.23 11.82 5 9 423 43.9 4.31 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 11.81 1 3 3 4 6.139E7 217.63 11.81 3 4 381 40.5 4.51 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 11.79 1 2 2 4 9.625E7 0.00 11.79 2 2 92.66 11.79 2 2 280 30.0 4.92 HVO_2610 deoxyribose-phosphate aldolase 11.79 1 2 2 4 1.975E8 2.52 11.79 2 2 146.26 11.79 2 2 212 21.9 4.23 HVO_0228 ParA domain protein 11.74 1 2 2 3 3.151E8 345.23 11.74 2 3 247 24.6 4.16 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 11.64 1 4 4 16 1.480E8 16.18 11.64 4 8 896.52 11.64 4 8 378 39.8 4.45 HVO_1140 acyl-CoA dehydrogenase 11.58 1 4 4 10 2.705E8 6.23 11.58 4 5 498.09 11.58 4 5 380 41.2 4.55 HVO_0868 NAD-dependent epimerase/dehydratase 11.55 1 4 4 8 1.302E8 1.74 7.60 3 4 213.29 11.55 4 4 329 36.1 4.55 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 11.50 1 3 3 10 6.651E7 6.53 11.50 3 5 390.99 11.50 3 5 287 31.8 4.93 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 11.42 1 3 3 14 2.208E8 6.61 11.42 3 7 592.10 11.42 3 7 464 53.1 4.54 HVO_1311 probable oxidoreductase (short-chain dehydrogenase family) 11.39 1 3 3 10 2.775E8 4.57 11.39 3 5 555.68 11.39 3 5 281 30.1 4.46 HVO_0911 GTP-binding protein Drg 11.38 1 4 4 10 1.107E8 2.20 11.38 4 4 413.95 11.38 4 6 369 40.5 4.81 HVO_0853 DNA double-strand break repair protein Mre11 11.34 1 3 3 9 1.696E8 8.93 7.94 2 4 487.78 11.34 3 5 441 48.1 4.39 HVO_1129 conserved hypothetical protein 11.28 1 3 3 11 1.805E8 10.87 11.28 3 5 624.09 11.28 3 6 390 43.0 4.44 HVO_1625 conserved hypothetical protein 11.16 1 5 5 16 2.698E8 19.37 11.16 5 8 1214.13 11.16 5 8 654 70.1 4.04 HVO_2918 thymidylate synthase 11.14 1 2 2 6 7.527E7 4.93 11.14 2 3 198.85 11.14 2 3 332 37.5 4.61 HVO_B0149 oleate hydratase 11.07 1 3 3 10 5.588E7 2.00 4.69 2 4 320.53 11.07 3 6 533 60.1 4.64 HVO_1038 uracil-DNA glycosylase superfamily protein 11.06 1 2 2 4 9.698E7 0.00 11.06 2 2 112.79 11.06 2 2 208 22.7 4.61 HVO_1685 conserved hypothetical protein 10.98 1 5 5 16 1.757E8 1.95 10.98 5 8 626.09 10.98 5 8 492 54.5 5.74 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 10.97 1 2 2 6 5.155E7 1.78 10.97 2 3 226.01 10.97 2 3 237 25.4 4.46 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 10.96 1 3 3 14 2.170E8 11.90 10.96 3 7 609.63 10.96 3 7 365 39.0 4.61 HVO_A0465 TetR family transcription regulator 10.95 1 2 2 2 7.311E7 104.81 10.95 2 2 210 23.7 4.48 HVO_C0044 PLD domain protein 10.81 1 2 2 6 7.509E7 4.72 10.81 2 3 235.21 10.81 2 3 333 36.4 4.94 HVO_1453 glutamate dehydrogenase (NADP) 10.79 1 4 4 12 3.592E8 8.34 10.79 4 5 701.09 10.79 4 7 417 45.7 4.49 HVO_1460 enoyl-CoA hydratase 10.78 1 2 2 3 1.551E7 3.37 10.78 2 3 269 28.2 4.49 HVO_0452 leucine--tRNA ligase 10.65 1 7 7 30 2.873E8 19.38 10.65 7 15 1401.25 10.65 7 15 958 109.5 4.37 HVO_2380 AAA-type ATPase (CDC48 subfamily) 10.63 1 6 6 14 2.126E8 2.18 9.56 5 7 407.78 9.56 5 7 743 81.9 4.82 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 10.63 1 3 3 9 1.283E8 2.50 7.09 2 3 386.71 10.63 3 6 395 42.4 4.54 HVO_2777 30S ribosomal protein S9 10.61 1 2 2 2 2.734E7 168.48 10.61 2 2 132 14.7 9.74 HVO_A0452 UspA domain protein 10.58 1 3 3 6 2.761E7 0.00 10.58 3 3 224.08 10.58 3 3 293 31.3 4.63 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 10.57 1 2 2 4 1.192E7 1.89 10.57 2 2 165.06 10.57 2 2 265 28.7 4.87 HVO_0120 signal recognition particle receptor FtsY 10.53 1 3 3 6 9.074E7 3.79 10.53 3 3 313.76 10.53 3 3 456 48.2 4.17 HVO_0867 HD family hydrolase 10.43 1 2 2 6 8.074E6 5.77 10.43 2 3 508.64 10.43 2 3 230 26.2 4.78 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 10.43 1 3 3 7 1.591E8 0.00 8.41 2 3 206.06 10.43 3 4 345 36.9 4.68 HVO_1073 ThiJ/PfpI family protein 10.27 1 2 2 10 1.263E8 8.68 10.27 2 5 461.07 10.27 2 5 224 23.9 4.12 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 10.23 1 4 4 10 2.007E8 7.92 10.23 4 6 289.93 10.23 4 4 430 45.1 4.50 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 10.20 1 2 2 4 2.297E8 4.27 10.20 2 2 190.50 10.20 2 2 353 36.7 4.65 HVO_0304 electron transfer flavoprotein alpha subunit 10.09 1 2 2 4 3.410E8 323.54 10.09 2 4 317 33.5 4.18 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 4 1.904E7 372.99 10.00 2 4 190 21.0 4.74 HVO_B0266 glutamate dehydrogenase (NAD) 9.89 1 4 4 10 7.219E7 11.59 9.89 4 5 696.03 9.89 4 5 435 47.3 4.63 HVO_B0143 receiver/sensor box histidine kinase 9.88 1 5 5 12 2.066E8 9.18 8.21 4 5 594.19 9.88 5 7 597 66.0 4.41 HVO_2564 50S ribosomal protein L3 9.76 1 3 3 6 2.423E7 3.84 9.76 3 3 213.72 9.76 3 3 338 37.2 6.68 HVO_1323 "shikimate kinase, archaeal-type" 9.69 1 2 2 10 4.556E8 8.76 9.69 2 4 557.29 9.69 2 6 289 29.5 4.30 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 9.66 1 2 2 2 1.481E8 87.06 9.66 2 2 383 41.9 4.21 HVO_0818 threonine synthase 9.51 1 2 3 14 5.622E8 7.01 9.51 3 7 622.97 5.40 2 7 389 40.8 4.31 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 9.51 1 2 2 6 1.496E8 4.70 9.51 2 3 307.91 9.51 2 3 305 34.1 4.91 HVO_2501 alpha/beta hydrolase fold protein 9.49 1 2 2 4 2.925E7 5.41 9.49 2 2 235.89 9.49 2 2 316 35.3 5.72 HVO_0123 signal recognition particle 54K protein 9.46 1 3 3 7 1.485E8 6.65 7.31 2 3 394.90 9.46 3 4 465 50.9 4.50 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 9.44 1 2 2 11 5.899E7 14.24 9.44 2 5 769.20 9.44 2 6 339 38.1 4.50 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 9.44 1 3 3 7 2.722E8 3.85 6.39 2 3 321.35 9.44 3 4 360 38.5 4.45 HVO_B0200 malate synthase 9.40 1 2 2 7 7.040E8 9.12 9.40 2 3 486.81 9.40 2 4 436 48.3 4.30 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 9.30 1 4 4 28 3.864E8 21.33 9.30 4 14 1303.67 9.30 4 14 430 44.2 4.37 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 9.26 1 3 3 9 3.075E8 7.73 9.26 3 4 490.58 9.26 3 5 324 36.6 4.68 HVO_1199 acyl-CoA dehydrogenase 9.21 1 3 3 9 1.019E8 6.36 9.21 3 4 484.09 9.21 3 5 380 41.5 4.64 HVO_2160 conserved hypothetical protein 9.17 1 14 14 90 1.394E9 80.46 9.17 14 46 5666.91 8.64 13 44 2257 232.7 3.92 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 9.11 1 0 5 21 3.228E8 14.43 9.11 5 11 1270.09 7.20 4 10 472 51.6 5.16 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 9.09 1 0 5 21 3.228E8 14.43 9.09 5 11 1270.09 7.19 4 10 473 51.2 5.05 HVO_0979 NADH dehydrogenase-like complex subunit B 9.01 1 2 2 6 1.855E8 4.01 9.01 2 3 316.25 9.01 2 3 233 26.1 5.01 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 8.99 1 5 5 12 7.619E8 8.99 8.99 5 6 709.39 8.99 5 6 612 67.3 4.16 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 8.99 1 4 4 12 1.328E8 3.57 8.99 4 6 410.97 8.99 4 6 634 66.1 4.54 HVO_2250 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 8.84 1 2 2 2 1.477E8 0.00 8.84 2 2 181 19.5 4.28 HVO_0848 endonuclease III 8.81 1 2 2 5 1.864E7 3.61 8.81 2 3 128.60 8.81 2 2 227 25.5 4.55 HVO_1356 sensor box histidine kinase 8.73 1 3 3 10 1.947E8 6.99 8.73 3 5 398.18 8.73 3 5 550 61.1 4.60 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 8.67 1 2 2 2 1.067E8 122.31 8.67 2 2 323 34.9 5.24 HVO_2427 replication factor C large subunit 8.61 1 4 4 10 7.593E7 9.72 8.61 4 5 464.15 8.61 4 5 488 53.4 4.67 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 8.61 1 1 2 7 2.145E8 4.77 8.61 2 4 291.26 8.61 2 3 267 28.8 4.55 HVO_0733 transcription initiation factor TFB 8.59 1 0 3 10 6.599E8 7.77 8.59 3 5 683.84 8.59 3 5 326 37.2 6.00 HVO_1578 probable NADH dehydrogenase 8.56 1 2 2 3 9.868E7 6.40 8.56 2 3 397 42.8 4.40 HVO_1783 conserved hypothetical protein 8.48 1 2 2 6 2.553E7 5.18 8.48 2 3 275.20 8.48 2 3 224 24.1 5.90 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 8.48 1 2 2 10 1.330E8 6.08 8.48 2 6 240.80 8.48 2 4 401 43.1 4.60 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 8.36 1 4 4 5 9.398E7 471.06 8.36 4 5 658 72.1 4.70 HVO_1097 diaminopimelate epimerase 8.33 1 2 2 6 4.761E7 7.57 8.33 2 3 300.94 8.33 2 3 288 29.9 4.48 47132620 keratin 2a [Homo sapiens] 8.29 1 3 6 37 9.247E8 27.40 8.29 6 17 2284.26 8.29 6 20 639 65.4 8.00 HVO_0670 glutathione S-transferase 8.28 1 3 3 3 4.766E7 168.01 8.28 3 3 326 38.1 4.56 HVO_B0038A D-xylonate dehydratase 8.25 1 1 3 14 2.867E8 5.26 8.25 3 8 532.91 4.61 2 6 412 45.5 4.55 HVO_B0324 conserved hypothetical protein 8.24 1 3 3 8 8.930E7 2.51 8.24 3 4 431.52 8.24 3 4 449 48.0 4.58 HVO_0551 DNA mismatch repair protein MutL 8.16 1 4 4 9 1.812E8 5.57 8.16 4 6 272.81 3.67 2 3 735 78.7 4.50 HVO_B0057 precorrin-3B C17-methyltransferase 8.14 1 3 3 10 3.196E8 10.22 6.69 2 5 782.79 5.52 2 5 344 36.3 4.31 HVO_0893 methylmalonyl-CoA mutase subunit A 8.13 1 3 3 10 1.223E8 8.00 8.13 3 5 439.78 8.13 3 5 566 63.1 4.36 HVO_0322 MinD/ParA domain protein 8.09 1 2 2 14 1.102E8 8.38 8.09 2 7 776.42 8.09 2 7 581 58.8 3.70 HVO_1424 conserved hypothetical protein 8.08 1 2 2 3 6.258E7 1.86 8.08 2 3 359 40.9 4.60 HVO_2153 probable copper-containing oxidoreductase 8.05 1 2 2 6 2.319E8 8.45 8.05 2 3 425.31 8.05 2 3 385 42.1 5.82 HVO_2923 proteasome alpha subunit 8.03 1 1 2 7 6.771E8 3.58 8.03 2 4 300.21 8.03 2 3 249 26.7 4.39 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 8.02 1 2 2 6 3.239E7 7.00 8.02 2 3 288.43 8.02 2 3 349 37.0 4.70 HVO_2211 TrkA domain protein 7.93 1 2 2 2 1.476E8 114.79 7.93 2 2 227 24.5 4.72 HVO_1553 hydroxypyruvate reductase 7.92 1 3 3 6 3.444E7 4.85 7.92 3 3 278.14 7.92 3 3 442 45.2 4.50 HVO_0197 PurE family protein 7.91 1 2 2 2 5.357E7 104.76 7.91 2 2 253 25.5 4.42 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 7.87 1 0 4 11 2.592E8 8.54 7.87 4 6 700.30 5.79 3 5 432 48.1 5.02 HVO_0042 acetylornithine deacetylase 7.87 1 2 2 7 3.824E8 6.41 7.87 2 3 364.60 7.87 2 4 381 41.0 4.34 HVO_1058 TrkA domain protein 7.87 1 3 3 8 1.865E8 6.93 7.87 3 4 522.91 7.87 3 4 445 47.7 4.35 HVO_2158 malic enzyme (NADP) 7.59 1 0 4 25 3.627E8 18.31 7.59 4 13 1194.49 6.79 3 12 751 81.4 4.55 HVO_B0001 Orc1-type DNA replication protein 7.56 1 3 3 7 1.416E8 4.19 5.37 2 3 284.60 7.56 3 4 410 45.8 5.33 HVO_0469 AstE family protein 7.55 1 2 2 8 2.531E8 7.16 7.55 2 4 431.74 7.55 2 4 318 33.9 5.85 HVO_A0586 sugar nucleotidyltransferase 7.54 1 2 2 8 1.724E8 4.69 7.54 2 4 362.22 7.54 2 4 411 43.7 4.69 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 7.51 1 4 4 13 2.560E8 6.32 7.51 4 7 625.07 4.96 3 6 706 73.3 4.39 HVO_0745 "FtsZ family protein, type III" 7.50 1 2 2 8 6.836E7 5.85 7.50 2 4 352.28 7.50 2 4 360 37.1 4.51 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 7.47 1 3 3 9 7.173E7 9.82 5.19 2 4 574.69 7.47 3 5 482 50.6 4.31 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 7.46 1 0 4 11 2.592E8 8.54 7.46 4 6 700.30 5.48 3 5 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 7.46 1 0 4 11 2.592E8 8.54 7.46 4 6 700.30 5.48 3 5 456 49.2 4.77 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 7.43 1 2 2 7 1.885E8 0.00 7.43 2 3 185.48 7.43 2 4 377 39.2 4.18 HVO_0195 ribose-5-phosphate isomerase 7.39 1 2 2 6 2.371E8 3.77 7.39 2 3 277.86 7.39 2 3 230 23.2 4.54 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 7.34 1 2 2 4 1.341E7 3.77 7.34 2 2 140.98 7.34 2 2 286 30.8 4.46 HVO_0826 peptidase M42 family protein 7.18 1 2 2 6 1.856E7 0.00 7.18 2 3 200.37 7.18 2 3 348 37.7 4.54 HVO_2600 methionyl aminopeptidase 7.09 1 2 2 4 1.691E8 382.76 7.09 2 4 296 32.3 4.41 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 6 1.001E8 4.28 7.07 2 3 240.38 7.07 2 3 297 32.3 3.98 HVO_2883 conserved hypothetical protein 6.98 1 5 5 12 9.576E7 6.48 5.56 4 6 431.97 6.27 4 6 702 78.9 4.48 HVO_1413 probable NADH dehydrogenase 6.90 1 2 2 2 3.224E7 1.67 6.90 2 2 377 39.7 4.67 HVO_0760 "probable glycosyltransferase, type 2" 6.79 1 2 2 2 5.632E7 1.61 6.79 2 2 368 40.7 4.82 HVO_2001 tRNA-guanine(15) transglycosylase 6.78 1 2 2 10 4.807E7 12.09 6.78 2 5 486.20 6.78 2 5 516 56.3 4.59 HVO_0001 Orc1-type DNA replication protein 6.74 1 2 2 2 1.032E7 0.00 6.74 2 2 564 62.1 4.39 HVO_0968 NADH dehydrogenase-like complex subunit CD 6.74 1 0 4 9 2.768E8 8.52 6.74 4 5 500.78 5.32 3 4 564 63.3 4.60 HVO_0464 threonine ammonia-lyase 6.70 1 2 2 5 5.785E7 2.55 6.70 2 2 223.76 6.70 2 3 403 43.7 4.72 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 6.69 1 2 2 14 6.956E8 10.08 6.69 2 7 544.61 6.69 2 7 299 32.0 4.53 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 6.67 1 2 2 9 2.109E8 6.48 6.67 2 4 426.28 6.67 2 5 360 39.5 4.31 HVO_1710 alpha amylase 6.65 1 5 5 20 1.526E8 7.30 6.65 5 10 842.50 6.65 5 10 677 75.0 4.45 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 6.65 1 2 2 6 4.762E7 5.02 6.65 2 3 172.09 6.65 2 3 406 43.1 4.60 HVO_0854 DNA double-strand break repair ATPase Rad50 6.61 1 4 4 13 7.715E7 6.76 5.60 3 6 563.15 6.61 4 7 893 100.0 4.58 HVO_2932 GTP-binding protein 6.57 1 2 2 3 3.330E8 0.00 6.57 2 3 396 43.5 4.51 HVO_1500 1-phosphofructokinase 6.56 1 2 2 2 2.250E7 190.16 6.56 2 2 305 32.0 4.51 HVO_2350 YyaL family protein 6.52 1 2 2 8 1.838E8 6.11 6.52 2 4 387.48 6.52 2 4 552 58.8 4.59 HVO_C0077 sarcosine oxidase 6.46 1 2 2 4 9.021E7 2.14 6.46 2 2 132.83 6.46 2 2 387 42.9 4.70 HVO_1309 peptidase M24 family protein 6.39 1 2 2 6 7.581E7 4.67 6.39 2 3 263.48 6.39 2 3 391 42.1 4.36 HVO_0662 HTH domain protein / thiamine-phosphate synthase 6.35 1 2 2 6 5.029E7 3.68 6.35 2 3 302.66 6.35 2 3 299 31.9 4.44 HVO_2266 hypothetical protein 6.29 1 2 2 8 0.000E0 1.69 6.29 2 4 344.55 6.29 2 4 493 56.7 4.54 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 6.20 1 2 2 4 1.026E8 1.93 6.20 2 2 207.10 6.20 2 2 516 56.7 4.89 HVO_0321 peptide chain release factor aRF-1 6.04 1 2 2 6 2.192E8 2.40 6.04 2 3 249.63 6.04 2 3 414 46.6 4.83 HVO_A0092 acyl-CoA dehydrogenase 6.04 1 2 2 4 2.502E7 0.00 6.04 2 2 104.01 6.04 2 2 381 42.2 4.83 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 5.99 1 2 2 6 1.249E8 0.00 5.99 2 3 162.78 5.99 2 3 584 63.3 4.79 HVO_A0328 2-keto-3-deoxygluconate kinase 5.97 1 1 2 5 1.430E8 1.76 5.97 2 2 249.91 5.97 2 3 318 34.0 4.60 HVO_B0154 receiver/sensor box histidine kinase 5.92 1 6 6 16 1.459E8 7.01 5.92 6 8 545.29 5.92 6 8 1301 144.1 4.39 HVO_1711 glucoamylase 5.89 1 6 6 13 1.395E8 10.87 4.50 5 6 670.34 5.89 6 7 1511 166.1 4.64 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 5.88 1 2 2 4 1.307E8 2.09 5.88 2 2 237.63 5.88 2 2 459 50.5 4.63 HVO_0741 DNA-directed DNA polymerase X 5.84 1 2 2 4 6.841E7 3.70 5.84 2 2 186.75 5.84 2 2 582 62.6 4.44 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 5.81 1 3 3 4 1.130E8 0.00 4.59 2 2 77.50 3.38 2 2 740 85.6 4.70 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 5.75 1 0 3 5 3.772E8 0.00 5.75 3 3 165.63 3.50 2 2 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 5.75 1 0 3 5 3.772E8 0.00 5.75 3 3 165.63 3.50 2 2 400 44.1 5.14 HVO_C0057 Orc1-type DNA replication protein 5.74 1 2 2 4 5.611E7 0.00 5.74 2 2 173.96 5.74 2 2 418 46.3 5.02 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 5.67 1 2 2 4 2.713E7 1.67 5.67 2 2 158.89 5.67 2 2 388 41.9 4.35 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 5.61 1 3 3 8 1.411E8 0.00 4.30 2 4 125.32 5.61 3 4 838 89.1 4.65 HVO_1375 O-succinylbenzoic acid--CoA ligase 5.54 1 2 2 3 8.929E7 360.71 5.54 2 3 614 64.7 4.28 HVO_1725 Orc1-type DNA replication protein 5.49 1 2 2 4 1.180E7 1.94 5.49 2 2 153.62 5.49 2 2 401 44.5 5.19 HVO_0639 AAA-type ATPase (MoxR subfamily) 5.38 1 2 2 6 6.457E7 4.20 5.38 2 3 313.98 5.38 2 3 316 34.7 4.89 HVO_1354 DNA mismatch repair protein MutS 5.34 1 2 2 3 6.326E7 203.25 5.34 2 3 580 62.1 4.56 HVO_3000 DNA ligase (NAD) 5.29 1 3 3 9 1.038E9 6.96 5.29 3 5 616.35 3.86 2 4 699 75.8 4.50 HVO_C0042 helicase domain protein 5.26 1 5 5 14 2.073E8 8.18 5.26 5 7 765.31 5.26 5 7 1274 144.4 4.67 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 5.25 1 2 2 2 5.976E7 105.81 5.25 2 2 438 46.4 4.58 HVO_0744 homolog to carboxylate-amine ligase 5.15 1 2 2 2 3.030E8 146.78 5.15 2 2 369 41.7 4.88 HVO_1113 "FtsZ family protein, type III" 5.14 1 0 2 4 4.741E8 1.84 5.14 2 2 122.39 5.14 2 2 389 40.8 4.89 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 5.01 1 2 2 6 1.478E7 2.03 5.01 2 3 200.71 5.01 2 3 379 41.7 4.83 HVO_A0257 Orc1-type DNA replication protein 4.94 1 2 2 7 2.619E7 0.00 4.94 2 3 268.94 4.94 2 4 425 48.0 4.94 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 4.88 1 2 2 6 1.920E8 3.69 4.88 2 3 269.99 4.88 2 3 492 52.1 4.83 HVO_2321 bacterial-type DNA primase DnaG 4.87 1 2 2 8 9.264E7 1.82 4.87 2 4 380.62 4.87 2 4 472 49.4 4.36 HVO_1340 "probable glycosyltransferase, type 1" 4.80 1 2 2 4 5.598E7 1.74 4.80 2 2 234.95 4.80 2 2 375 41.0 4.42 HVO_C0001 Orc1-type DNA replication protein 4.66 1 2 2 3 1.170E8 214.70 4.66 2 3 408 45.2 4.97 HVO_A0158 acyl-CoA synthetase 4.62 1 0 3 16 8.636E8 8.67 4.62 3 8 904.78 4.62 3 8 650 71.2 4.63 HVO_0689 chromosome segregation protein Smc 4.52 1 4 5 11 1.079E8 6.08 4.03 4 5 498.74 4.52 5 6 1240 138.1 4.39 HVO_B0111 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 4.49 1 2 2 4 3.759E7 2.05 4.49 2 2 103.63 4.49 2 2 401 44.2 4.54 HVO_0069 sulfatase 4.47 1 3 3 5 2.594E7 1.69 3.11 2 2 168.45 4.47 3 3 515 57.4 4.35 HVO_1723 DNA repair helicase Rad25 4.32 1 2 2 2 2.316E7 2.73 4.32 2 2 695 76.8 4.69 HVO_C0043 conserved hypothetical protein 4.24 1 3 3 7 6.337E7 2.37 4.24 3 4 221.21 4.24 3 3 661 73.8 4.75 HVO_2871 pyridoxal phosphate-dependent aminotransferase 4.22 1 2 2 4 4.890E7 2.47 4.22 2 2 156.07 4.22 2 2 450 49.1 4.70 HVO_0896 acyl-CoA synthetase 4.07 1 2 2 6 4.246E7 5.01 4.07 2 3 177.14 4.07 2 3 540 59.8 4.56 HVO_B0233 alpha-L-arabinofuranosidase 3.72 1 2 2 4 3.260E7 1.94 3.72 2 2 164.29 3.72 2 2 511 57.5 4.39 21961227 Keratin 6B [Homo sapiens] 3.55 1 0 3 20 2.514E8 3.22 3.55 3 9 966.77 3.55 3 11 564 60.0 8.00 31074631 keratin 1b [Homo sapiens] 3.46 1 0 2 18 6.679E8 9.10 3.46 2 8 1120.16 3.46 2 10 578 61.8 5.97 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 12 2.141E8 5.89 3.45 2 6 630.06 3.45 2 6 464 50.6 5.47 4557890 keratin 5 [Homo sapiens] 3.22 1 0 3 16 2.331E8 5.30 3.22 3 7 975.87 3.22 3 9 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 3.22 1 0 3 16 2.331E8 5.30 3.22 3 7 975.87 3.22 3 9 590 62.4 8.06 HVO_0014 ATP-dependent DNA helicase Hel308a 3.14 1 2 2 6 1.012E7 4.94 3.14 2 3 255.43 3.14 2 3 827 90.3 4.67 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 2.60 1 0 2 14 2.331E8 3.22 2.60 2 6 859.11 2.60 2 8 384 42.4 5.40 4504919 keratin 8 [Homo sapiens] 2.07 1 0 2 14 2.331E8 3.22 2.07 2 6 859.11 2.07 2 8 483 53.7 5.59 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 1.77 1 0 2 14 2.331E8 3.22 1.77 2 6 859.11 1.77 2 8 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 1.77 1 0 2 14 2.331E8 3.22 1.77 2 6 859.11 1.77 2 8 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 1.77 1 0 2 14 2.331E8 3.22 1.77 2 6 859.11 1.77 2 8 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 1.77 1 0 2 14 2.331E8 3.22 1.77 2 6 859.11 1.77 2 8 564 60.0 7.72