Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_2548 50S ribosomal protein L6 92.13 1 11 11 294 7.958E8 361.92 91.01 10 139 20142.55 92.13 11 155 178 19.6 4.68 HVO_2757 50S ribosomal protein L1 83.49 1 16 16 941 2.544E9 1352.00 78.77 14 466 58900.40 83.49 16 475 212 23.1 4.42 HVO_1507 acetolactate synthase small subunit 83.03 1 16 16 103 1.150E8 109.29 83.03 16 51 6252.45 83.03 16 52 218 23.7 4.94 HVO_2779 50S ribosomal protein L18e 81.03 1 10 10 101 3.400E8 141.54 81.03 10 51 6892.28 81.03 10 50 116 12.7 8.50 HVO_1454 aspartate carbamoyltransferase catalytic subunit 79.61 1 15 15 91 9.390E7 94.34 79.61 15 45 5101.30 79.61 15 46 304 33.7 4.92 HVO_1145 30S ribosomal protein S1e 79.55 1 18 18 898 1.952E9 1037.92 79.55 18 445 44416.94 79.55 18 453 220 24.8 4.86 HVO_2564 50S ribosomal protein L3 78.11 1 22 22 883 3.437E9 878.61 78.11 21 442 47582.63 76.33 21 441 338 37.2 6.68 HVO_2555 30S ribosomal protein S17 74.56 1 5 5 79 1.367E8 81.37 55.26 4 38 4594.69 74.56 5 41 114 12.7 4.81 HVO_2380 AAA-type ATPase (CDC48 subfamily) 74.16 1 53 53 494 7.234E8 461.10 74.16 52 247 25264.95 73.49 52 247 743 81.9 4.82 HVO_1400 ABC-type transport system ATP-binding protein (probable substrate sugar) 73.99 1 25 25 169 1.388E8 169.56 64.35 23 85 8249.64 73.99 25 84 519 56.8 4.68 HVO_0133 thermosome subunit 1 73.21 1 32 33 3751 5.359E9 4729.48 73.21 33 1869 208264.34 73.21 33 1882 560 58.9 4.25 HVO_0778 thermosome subunit 3 73.09 1 35 36 2183 5.351E9 3185.04 73.09 36 1100 150594.21 73.09 36 1083 524 55.2 4.59 HVO_2545 50S ribosomal protein L18 72.83 1 5 5 172 5.384E8 203.77 72.83 5 85 7977.02 72.83 5 87 184 20.2 5.60 HVO_0455 thermosome subunit 2 71.99 1 36 36 3560 4.254E9 5210.54 71.99 36 1788 248029.54 71.99 36 1772 557 59.3 4.37 HVO_2759 peptidase M42 family protein 70.62 1 18 18 180 2.437E8 229.28 70.62 18 91 10445.80 70.62 18 89 354 37.0 4.40 HVO_1858 30S ribosomal protein S19e 70.20 1 8 8 43 1.250E8 33.16 58.28 7 18 3016.10 70.20 8 25 151 16.7 4.84 HVO_2562 50S ribosomal protein L23 69.88 1 6 6 94 1.351E8 102.24 56.63 5 45 6273.54 69.88 6 49 83 9.4 5.48 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 69.58 1 14 14 102 1.827E8 130.16 69.58 14 51 6058.20 69.58 14 51 355 38.2 4.68 HVO_2563 50S ribosomal protein L4 69.35 1 13 13 497 1.315E9 537.22 69.35 13 238 26793.54 69.35 13 259 248 27.0 6.44 HVO_2724 beta-lactamase domain protein 69.33 1 26 26 441 1.316E9 362.38 68.00 25 219 20457.72 68.22 25 222 450 50.1 5.40 HVO_0239 glutamine synthetase 68.64 1 29 29 1506 4.669E9 1872.40 63.16 28 746 95186.17 66.01 26 760 456 50.5 4.56 HVO_0356 translation elongation factor aEF-2 68.64 1 39 39 442 6.986E8 518.09 64.37 36 218 23179.34 68.64 39 224 727 80.4 4.73 HVO_0329 branched-chain amino acid aminotransferase 67.63 1 19 19 292 5.512E8 366.10 67.63 19 144 19405.23 67.63 19 148 312 35.0 4.58 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 66.86 1 14 14 229 4.864E8 271.57 66.86 14 114 12779.40 66.86 14 115 350 37.6 4.54 HVO_0725 probable oxidoreductase (short-chain dehydrogenase family) 66.19 1 14 14 179 4.488E8 208.20 66.19 14 90 11738.44 66.19 14 89 281 30.2 4.78 HVO_2900 fumarate hydratase 66.10 1 18 18 183 5.846E8 210.35 65.03 17 92 9944.09 66.10 18 91 469 50.1 4.78 HVO_0359 translation elongation factor aEF-1 alpha subunit 65.80 1 16 19 450 1.010E9 538.52 60.57 17 215 28249.17 65.80 19 235 421 45.7 4.73 HVO_0313 A-type ATP synthase subunit E 64.95 1 8 9 46 9.525E7 37.16 57.73 7 18 3082.32 64.95 9 28 194 22.0 4.31 HVO_2756 50S ribosomal protein L10 64.66 1 13 13 574 8.316E8 734.17 62.93 12 289 27441.96 64.66 13 285 348 36.9 3.99 HVO_1273 inosine-5'-monophosphate dehydrogenase 63.45 1 19 19 388 4.790E8 418.01 60.84 18 194 21051.86 63.45 19 194 498 53.3 4.55 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 63.27 1 16 16 124 2.520E8 139.97 63.27 16 62 7849.37 63.27 16 62 422 43.6 4.72 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 62.37 1 12 12 281 8.029E8 256.20 62.37 12 140 14228.56 62.37 12 141 287 31.0 4.73 HVO_0677 aspartate--tRNA ligase 62.21 1 18 18 209 3.822E8 235.88 59.68 17 105 10516.21 62.21 18 104 434 48.7 4.50 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 62.10 1 29 30 339 4.842E8 385.06 62.10 30 171 20059.45 62.10 30 168 599 65.3 4.51 HVO_2205 arNOG06768 family NADH-binding domain protein 61.79 1 13 13 98 5.499E7 139.09 52.49 12 49 6578.77 61.79 13 49 301 32.0 5.00 HVO_2013 "FtsZ family protein, type III" 61.68 1 11 11 91 6.239E7 106.05 61.68 11 46 4230.15 52.03 10 45 394 41.5 4.61 HVO_0880 conserved hypothetical protein 61.56 1 19 19 134 4.470E7 93.11 57.65 17 67 5911.90 61.56 19 67 307 36.3 4.74 HVO_0117 translation initiation factor aIF-6 61.54 1 8 8 44 1.799E8 65.16 57.47 7 22 2640.44 44.80 7 22 221 23.0 4.27 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 61.47 1 19 19 186 3.325E8 204.42 59.41 18 93 11491.27 58.24 16 93 340 38.8 4.58 HVO_2862 serine hydroxymethyltransferase 61.20 1 13 13 150 2.308E8 159.03 61.20 13 77 8498.09 61.20 13 73 415 44.3 4.53 HVO_2560 30S ribosomal protein S19 60.71 1 7 7 51 1.357E8 50.28 60.71 7 25 2614.50 60.71 7 26 140 16.0 5.57 HVO_0773 probable S-adenosylmethionine-dependent methyltransferase 60.56 1 15 15 71 1.688E8 66.77 60.56 15 35 4278.85 60.56 15 36 251 27.8 6.06 HVO_0980 NADH dehydrogenase-like complex subunit CD 59.96 1 21 27 442 1.183E9 446.85 56.19 25 217 26503.12 59.96 27 225 557 63.4 4.53 HVO_2336 pyridoxal biosynthesis lyase PdxS 59.93 1 13 13 134 2.572E8 152.86 56.29 11 61 8487.55 59.93 13 73 302 32.5 4.81 HVO_3014 origin-associated GTP-binding protein OapA 59.62 1 9 9 48 4.905E7 49.27 56.34 8 23 2133.23 59.62 9 25 213 24.0 5.01 HVO_1522 hexuronic acid methyltransferase AglP 59.41 1 13 13 68 1.718E8 54.80 59.41 13 34 3717.49 59.41 13 34 239 26.2 4.98 HVO_2542 50S ribosomal protein L15 59.39 1 9 9 220 5.316E8 292.95 59.39 9 109 14367.46 59.39 9 111 165 17.8 4.93 HVO_0812 phosphoenolpyruvate synthase 59.13 1 40 40 700 1.964E9 805.11 57.95 38 351 38442.78 59.13 40 349 761 83.1 4.63 HVO_0118 50S ribosomal protein L20e 58.62 1 3 3 11 3.639E7 8.23 58.62 3 6 477.38 43.10 2 5 58 6.4 6.52 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 58.62 1 13 13 937 1.980E9 998.75 58.62 13 483 38718.21 58.62 13 454 377 39.2 4.18 HVO_0817 phytoene dehydrogenase (phytoene desaturase) 57.88 1 22 22 178 2.804E8 204.32 57.88 22 91 9889.36 57.88 22 87 425 46.1 4.98 HVO_A0207 CRISPR-associated protein Cas7 57.65 1 13 13 216 3.831E8 222.07 51.76 12 109 10809.03 57.65 13 107 340 38.2 4.54 HVO_2554 50S ribosomal protein L14 57.58 1 10 10 261 8.295E8 314.32 57.58 10 132 12149.32 57.58 10 129 132 14.2 9.76 HVO_2784 30S ribosomal protein S13 57.49 1 10 10 118 9.166E8 121.03 46.71 8 54 8684.84 57.49 10 64 167 18.9 5.17 HVO_1506 ketol-acid reductoisomerase 57.18 1 13 13 361 3.751E8 277.12 52.87 11 154 18155.91 57.18 13 207 348 37.9 4.34 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 57.14 1 18 18 149 3.269E8 144.71 57.14 18 73 8059.56 57.14 18 76 336 38.0 4.61 HVO_0801 stomatin family protein 56.60 1 23 26 322 9.011E8 390.84 56.60 26 161 21139.84 56.60 25 161 424 46.4 4.37 HVO_0167 adenosylhomocysteinase 56.54 1 16 16 148 1.840E8 143.73 52.34 15 68 9212.85 56.54 16 80 428 46.6 4.39 HVO_2543 50S ribosomal protein L30 56.49 1 7 7 142 7.039E8 143.71 56.49 7 70 9061.44 56.49 7 72 154 17.1 4.77 HVO_1189 aldehyde dehydrogenase 55.91 1 23 23 311 5.723E8 238.77 48.62 22 149 13467.52 53.74 22 162 508 56.1 4.59 HVO_2889 RecJ domain protein 55.69 1 29 29 438 5.374E8 523.02 55.69 29 220 27882.35 52.26 28 218 729 79.1 4.37 HVO_1799 geranylgeranyl reductase / dolichol omega-reductase 55.37 1 15 15 109 2.037E8 109.72 55.37 14 52 7064.96 49.02 14 57 410 45.4 4.75 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 55.13 1 10 10 420 1.724E9 393.77 55.13 10 210 20490.69 55.13 10 210 312 34.5 4.98 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 55.03 1 14 14 150 6.742E8 189.41 55.03 14 75 9185.73 51.26 13 75 398 43.4 4.37 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 54.84 1 25 25 274 2.299E8 362.50 52.91 24 137 18378.39 54.84 25 137 516 56.7 4.89 HVO_2777 30S ribosomal protein S9 54.55 1 7 7 58 9.461E7 55.64 54.55 7 29 3269.59 54.55 7 29 132 14.7 9.74 HVO_2923 proteasome alpha subunit 53.82 1 10 11 62 2.152E8 62.32 53.82 11 31 3601.26 40.56 10 31 249 26.7 4.39 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 53.81 1 13 13 211 6.290E8 251.99 53.81 13 106 11796.17 53.81 13 105 381 41.0 4.23 HVO_2538 alpha/beta hydrolase fold protein 53.67 1 12 12 77 1.316E8 58.52 50.48 11 37 4499.45 53.67 12 40 313 33.8 6.06 HVO_2636 PspA domain protein 53.62 1 11 11 143 2.047E8 201.34 53.62 11 73 9721.01 53.62 11 70 276 30.9 4.61 HVO_2487 aspartate-semialdehyde dehydrogenase 53.49 1 10 10 134 2.984E8 140.05 53.49 10 68 5617.68 53.49 10 66 344 36.6 4.41 HVO_0869 glutamate synthase large subunit 53.47 1 60 61 514 2.240E8 591.19 53.21 60 255 31396.76 52.02 60 259 1511 163.8 4.70 HVO_2588 isocitrate dehydrogenase (NADP) 53.46 1 20 20 157 3.878E8 154.59 50.36 19 77 8600.14 53.46 20 80 419 45.8 4.59 HVO_2620 cytochrome bc1 complex Rieske iron-sulfur protein 53.38 1 6 6 111 2.793E8 130.33 53.38 6 56 6031.31 44.48 5 55 281 30.2 4.31 HVO_0317 A-type ATP synthase subunit B 52.99 1 19 19 302 1.299E9 355.41 52.99 19 151 17228.88 51.92 18 151 468 51.9 4.25 HVO_2547 50S ribosomal protein L32e 52.77 1 10 10 341 1.943E9 438.24 43.40 8 167 21886.50 52.77 10 174 235 25.8 4.75 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 52.61 1 21 22 520 3.132E9 541.65 51.35 21 261 27595.56 49.45 21 259 631 68.4 4.49 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 51.92 1 25 25 166 2.504E8 212.35 51.92 25 85 8643.80 47.76 24 81 624 67.6 4.27 HVO_0783 ATP-dependent protease La 51.01 1 24 24 191 2.761E8 179.03 51.01 24 95 9703.48 51.01 24 96 694 75.4 4.86 HVO_A0133 conserved hypothetical protein 50.68 1 14 14 200 8.539E8 259.52 50.68 14 103 12524.01 48.97 13 97 292 30.8 5.17 HVO_1094 ribonuclease P protein component 3 50.65 1 9 9 32 1.926E7 35.91 50.65 9 16 1543.56 47.19 8 16 231 25.6 5.31 HVO_2774 enolase 50.63 1 13 13 189 9.399E8 205.71 50.63 13 96 11690.25 49.37 12 93 399 42.0 4.37 HVO_2046 sulfatase domain protein 50.62 1 15 15 76 1.114E8 57.06 50.62 15 38 3315.35 50.62 15 38 405 45.5 4.87 HVO_0055 CBS domain protein 50.35 1 10 10 33 3.204E7 39.19 50.35 10 17 1873.13 46.13 9 16 284 30.8 4.27 HVO_2778 50S ribosomal protein L13 50.34 1 6 6 62 2.538E8 88.98 50.34 6 31 3980.18 50.34 6 31 145 16.0 5.43 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 50.26 1 13 13 102 2.129E8 99.63 50.26 13 49 5774.95 50.26 13 53 384 41.4 4.41 HVO_2552 30S ribosomal protein S4e 50.20 1 9 9 87 5.949E8 106.60 50.20 9 45 5168.23 50.20 9 42 247 26.6 4.58 HVO_1575 arginase 50.17 1 9 9 47 4.391E7 56.10 50.17 9 24 2363.65 50.17 9 23 299 31.0 4.58 HVO_2782 30S ribosomal protein S11 50.00 1 6 6 45 7.724E7 33.70 50.00 6 23 2258.92 50.00 6 22 130 13.4 8.56 HVO_0348 DNA-directed RNA polymerase subunit B' 49.92 1 19 19 109 6.664E7 141.15 49.92 19 56 6664.84 47.95 18 53 609 67.7 4.92 HVO_2436 malic enzyme (NADP) 49.80 1 20 26 279 3.612E8 322.46 49.80 26 139 17018.36 49.00 25 140 751 81.4 4.55 HVO_0087 porphobilinogen synthase 49.54 1 9 9 62 1.186E8 56.35 49.54 9 31 3094.57 49.54 9 31 327 35.3 4.72 HVO_1488 D-gluconate dehydratase 49.51 1 12 16 218 1.141E9 249.33 48.30 15 108 12828.70 49.51 16 110 412 45.8 4.60 HVO_0314 A-type ATP synthase subunit C 49.43 1 14 14 111 1.748E8 131.05 45.40 13 53 7658.03 44.83 13 58 348 38.7 4.50 HVO_0484 50S ribosomal protein L10e 49.43 1 11 11 153 1.151E9 137.09 49.43 11 76 8590.01 46.59 10 77 176 19.8 8.72 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 49.43 1 23 23 397 6.586E8 438.84 49.43 23 198 21242.31 49.43 23 199 615 67.6 4.88 HVO_0393 UvrABC system protein A 48.93 1 33 33 151 4.495E7 154.79 48.93 33 76 7795.62 48.32 32 75 983 108.6 4.82 HVO_0979 NADH dehydrogenase-like complex subunit B 48.50 1 11 11 88 2.641E8 75.05 40.34 10 41 5100.92 48.50 11 47 233 26.1 5.01 HVO_2559 50S ribosomal protein L22 48.37 1 5 5 44 8.808E7 41.11 38.56 4 18 3865.39 48.37 5 26 153 16.9 5.60 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 48.31 1 12 12 69 1.975E8 61.33 48.31 12 34 3455.92 48.31 12 35 445 47.8 4.86 HVO_1690 DHH family phosphoesterase 48.25 1 13 13 60 2.380E7 52.45 46.60 12 29 3123.25 48.25 13 31 485 52.1 4.48 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 48.17 1 24 24 354 7.365E8 400.58 48.17 24 176 19565.62 48.17 24 178 573 62.9 4.45 HVO_0861 SufB domain protein 48.01 1 15 15 184 2.248E8 227.97 44.53 14 90 11708.33 48.01 15 94 402 44.7 4.23 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 47.92 1 8 8 48 7.424E7 63.43 47.92 8 24 2516.91 47.92 8 24 265 29.3 4.92 HVO_0860 SufB domain protein 47.48 1 17 17 160 2.901E8 148.07 45.80 16 80 8750.47 47.48 17 80 476 53.2 4.69 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 47.44 1 21 21 348 8.599E8 407.13 43.86 20 173 21218.25 47.44 21 175 586 64.0 4.49 HVO_1346 GTP-binding protein HflX 47.34 1 16 16 84 5.438E7 83.52 47.34 16 41 4891.39 47.34 16 43 433 48.2 4.73 HVO_2204 "FtsZ family protein, type III" 47.34 1 13 16 138 1.695E8 158.99 47.34 16 69 8030.68 43.80 15 69 395 42.0 4.68 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 46.91 1 11 11 68 1.066E8 84.48 44.75 10 33 4804.90 46.91 11 35 324 36.6 4.68 HVO_2947 phenylalanine--tRNA ligase beta subunit 46.84 1 18 18 118 2.021E8 101.91 44.74 16 57 6596.88 46.84 18 61 570 63.3 4.46 HVO_2425 GNAT family acetyltransferase 46.76 1 8 8 58 6.980E7 50.68 46.76 8 29 2620.97 46.76 8 29 216 24.4 4.54 HVO_2708 YfiH family protein 46.58 1 9 9 61 1.480E8 74.56 46.58 9 30 3686.47 46.58 9 31 322 35.4 4.35 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 118 3.075E8 163.82 43.25 7 56 8003.38 46.37 8 62 289 29.8 4.27 HVO_1284 GTP cyclohydrolase III 46.36 1 9 9 31 3.646E7 30.41 37.55 8 15 1798.21 46.36 9 16 261 28.9 4.70 HVO_1578 probable NADH dehydrogenase 46.35 1 19 19 572 1.402E9 793.98 46.35 19 287 36706.40 46.35 19 285 397 42.8 4.40 HVO_1684 threonine--tRNA ligase 46.35 1 25 25 169 1.888E8 182.74 46.35 25 84 9520.35 46.35 25 85 643 73.4 4.45 HVO_1649 methionine adenosyltransferase 46.02 1 11 11 38 2.258E7 30.82 36.32 10 18 1569.32 46.02 11 20 402 43.5 4.45 HVO_0581 "cell division protein FtsZ, type II" 45.75 1 11 11 69 1.080E8 86.68 45.75 11 36 3421.98 45.75 11 33 400 42.5 4.75 HVO_1091 proteasome alpha subunit 45.63 1 12 13 221 1.159E9 237.91 45.63 13 110 12658.72 40.08 11 111 252 27.6 4.56 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 45.44 1 16 16 124 1.440E8 129.05 45.44 16 61 6101.28 45.44 16 63 471 51.0 4.48 40354192 keratin 10 [Homo sapiens] 45.21 1 0 26 192 2.280E8 186.63 45.21 26 96 10407.70 45.21 26 96 584 58.8 5.16 HVO_A0491 ABC-type transport system ATP-binding protein (probable substrate sugar) 45.17 1 10 10 68 7.644E7 91.08 42.56 9 33 4424.27 45.17 10 35 383 41.1 4.48 HVO_0025 thiosulfate sulfurtransferase 45.10 1 8 8 57 2.518E8 48.33 42.66 7 29 2566.03 45.10 8 28 286 32.1 4.28 HVO_0536 ferritin 44.89 1 4 4 49 5.977E7 66.72 44.89 4 24 2572.21 44.89 4 25 176 19.9 4.50 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 44.74 1 9 9 91 2.190E8 105.71 44.74 9 46 5191.91 44.74 9 45 266 27.8 4.84 HVO_0085 GlnK-type ammonia transport regulator 44.54 1 4 4 13 7.918E6 16.54 44.54 4 7 868.41 36.13 3 6 119 12.5 4.97 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 44.52 1 0 26 192 2.280E8 186.63 44.52 26 96 10407.70 44.52 26 96 593 59.5 5.21 HVO_1132 adenylosuccinate synthase 44.47 1 18 18 142 2.189E8 145.87 41.31 17 70 8476.31 44.47 18 72 443 48.2 4.56 HVO_0349 DNA-directed RNA polymerase subunit A' 44.36 1 33 33 390 3.680E8 444.35 44.36 33 195 23432.27 43.85 32 195 976 108.8 4.81 HVO_1020 HEAT-PBS family protein 44.15 1 17 17 337 6.542E8 343.37 39.86 16 160 22211.10 44.15 17 177 419 45.5 3.95 HVO_3007 malate dehydrogenase 44.08 1 11 11 144 6.129E8 183.20 41.12 10 74 8939.72 44.08 11 70 304 32.6 4.40 HVO_2553 50S ribosomal protein L24 44.07 1 5 5 60 3.439E8 47.65 44.07 5 30 3199.92 44.07 5 30 118 13.4 4.73 17318569 keratin 1 [Homo sapiens] 43.94 1 2 29 247 4.259E8 280.16 43.01 28 122 15731.63 43.32 28 125 644 66.0 8.12 HVO_1453 glutamate dehydrogenase (NADP) 43.88 1 14 14 93 9.474E7 80.21 38.13 13 46 4999.70 43.88 14 47 417 45.7 4.49 HVO_1568 alpha/beta hydrolase fold protein 43.68 1 8 8 30 2.572E7 36.24 43.68 8 15 1539.73 37.91 7 15 277 29.4 4.94 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 43.61 1 8 8 30 2.385E7 31.47 43.61 8 16 1469.39 28.20 6 14 305 32.7 4.56 HVO_2413 translation elongation factor aEF-1 alpha subunit 43.33 1 9 12 63 3.270E7 51.71 42.38 11 30 3150.99 43.33 12 33 420 45.6 4.75 HVO_2168 AAA-type ATPase (MoxR subfamily) 43.16 1 10 10 31 4.516E7 28.50 43.16 10 15 1577.42 36.47 9 16 329 35.9 4.54 HVO_2153 probable copper-containing oxidoreductase 43.12 1 15 15 155 4.033E8 160.65 41.30 14 76 9319.78 43.12 15 79 385 42.1 5.82 HVO_1348 probable YjeF family carbohydrate kinase 43.10 1 14 14 102 1.205E8 120.63 41.00 12 50 6725.61 43.10 14 52 478 48.8 4.45 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 43.07 1 17 17 97 1.466E8 115.65 43.07 17 49 5495.37 39.70 16 48 592 66.6 4.61 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 43.03 1 10 10 1590 4.497E8 2163.73 43.03 10 799 72850.88 43.03 10 791 574 62.8 4.17 HVO_2015 conserved hypothetical protein 42.90 1 9 9 94 3.276E8 92.83 42.90 9 47 5633.71 42.90 9 47 345 37.7 4.25 HVO_2968 phosphoglycerate dehydrogenase 42.86 1 15 15 144 2.021E8 194.70 42.86 15 72 9796.44 42.86 15 72 525 55.3 4.36 HVO_2561 50S ribosomal protein L2 42.74 1 13 13 501 2.219E9 497.15 42.74 12 249 29277.81 42.74 13 252 241 25.6 10.40 HVO_0850 proteasome-activating nucleotidase 42.72 1 11 11 71 2.095E7 77.98 42.72 11 35 4129.44 42.72 11 36 405 45.6 4.60 HVO_2749 50S ribosomal protein L21e 42.71 1 4 4 14 1.575E7 7.67 42.71 4 7 577.55 42.71 4 7 96 10.6 10.95 HVO_1673 conserved hypothetical protein 42.59 1 7 7 60 1.370E8 68.59 42.59 7 29 3761.35 42.59 7 31 216 23.2 4.58 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 42.55 1 0 27 213 4.259E8 256.15 41.61 26 105 14299.88 41.93 26 108 644 66.0 8.12 HVO_1084 adenylosuccinate lyase 42.55 1 13 14 71 1.576E8 78.10 42.55 14 36 4160.93 42.55 14 35 463 50.8 4.70 HVO_0870 proline--tRNA ligase 42.21 1 13 13 77 6.045E7 78.17 39.75 12 36 4604.41 42.21 13 41 488 54.9 4.44 HVO_2695 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 42.19 1 11 11 117 2.609E8 138.52 42.19 11 59 6455.28 42.19 11 58 512 55.4 4.42 HVO_1824 conserved hypothetical protein 41.96 1 11 11 44 4.875E7 60.89 33.80 10 22 2964.86 36.36 10 22 429 47.4 4.20 HVO_0446 ABC-type transport system ATP-binding protein (probable substrate phosphate/phosphonate) 41.95 1 8 8 56 7.519E7 51.30 38.20 7 24 3334.65 41.95 8 32 267 28.9 4.64 47132620 keratin 2a [Homo sapiens] 41.94 1 14 21 137 2.838E8 157.20 40.06 20 69 8307.86 41.31 20 68 639 65.4 8.00 HVO_0894 acyl-CoA synthetase 41.84 1 9 19 155 2.787E8 180.08 41.84 19 77 8858.95 41.84 19 78 662 74.3 4.48 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 41.80 1 10 10 48 1.929E7 50.88 35.60 9 24 2681.18 37.15 9 24 323 34.9 5.24 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 41.67 1 8 8 74 6.318E7 104.51 36.31 7 35 5648.95 41.67 8 39 336 36.8 4.12 HVO_A0156 acyl-CoA synthetase 41.42 1 7 17 131 2.497E8 140.50 41.42 17 66 7169.39 38.40 16 65 664 74.0 4.40 HVO_2624 CTP synthase 41.35 1 14 14 64 8.612E7 51.25 41.35 14 32 3004.12 38.43 13 32 549 60.8 4.70 HVO_1637 FKBP-type peptidylprolyl isomerase 41.18 1 8 8 66 9.300E7 61.73 32.68 7 32 3023.80 41.18 8 34 306 33.8 3.76 HVO_A0205 CRISPR-associated endoribonuclease Cas6 41.18 1 10 10 56 8.673E7 66.05 41.18 10 28 3535.29 41.18 10 28 272 31.0 5.44 HVO_2068 "FtsZ family protein, type III" 41.08 1 8 8 34 3.633E7 41.64 41.08 8 17 2229.07 33.24 7 17 370 38.7 4.49 HVO_2040 NAD-dependent epimerase/dehydratase 40.85 1 5 10 33 2.009E7 29.61 40.85 10 16 1651.97 40.85 10 17 306 33.8 4.51 HVO_2191 formyltetrahydrofolate deformylase 40.67 1 10 10 34 6.115E7 40.67 40.67 10 17 2062.11 40.67 10 17 327 36.2 4.63 HVO_1465 naphthoate synthase 40.66 1 9 9 66 5.333E7 70.78 35.08 8 32 3623.86 40.66 9 34 305 33.9 4.83 HVO_2948 phenylalanine--tRNA ligase alpha subunit 40.48 1 9 9 109 1.301E8 156.63 40.48 9 54 6786.30 40.48 9 55 499 55.1 4.41 HVO_2621 phosphoenolpyruvate carboxylase 40.47 1 28 28 237 2.286E8 241.72 40.47 28 119 12647.59 40.47 28 118 897 102.3 4.64 HVO_0718 protein translocase subunit SecE 40.35 1 2 2 8 1.414E7 8.38 40.35 2 4 388.58 40.35 2 4 57 6.2 8.62 HVO_1562 proteasome beta subunit 40.33 1 7 7 76 2.135E8 90.03 40.33 7 38 4681.40 40.33 7 38 243 26.0 4.63 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 28 3.083E7 26.28 40.26 5 14 1747.87 40.26 5 14 154 17.5 4.50 HVO_0206 alanine--tRNA ligase 40.13 1 27 27 220 6.041E7 156.12 39.26 26 101 11716.86 36.44 26 119 922 102.4 4.54 HVO_0806 pyruvate kinase 40.00 1 16 16 136 2.242E8 141.76 40.00 16 68 7625.77 40.00 16 68 585 62.0 4.54 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 51 9.663E7 41.65 40.00 4 25 2146.50 40.00 4 26 130 14.1 4.79 HVO_1502 3-isopropylmalate dehydrogenase 39.81 1 9 9 78 1.253E8 89.27 32.10 8 37 5348.76 39.81 9 41 324 33.7 4.23 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 39.72 1 11 11 48 6.834E7 33.83 39.72 11 24 2156.66 39.72 11 24 360 39.6 4.39 HVO_B0132 PQQ repeat protein 39.51 1 8 8 42 1.793E7 42.83 39.51 8 21 1793.56 39.51 8 21 405 41.9 4.64 HVO_0347 DNA-directed RNA polymerase subunit B'' 39.35 1 17 17 87 7.244E7 102.02 39.35 17 44 3899.53 39.35 17 43 521 58.9 5.00 HVO_0654 50S ribosomal protein L43e 39.33 1 3 3 16 5.450E7 14.72 39.33 3 8 923.04 39.33 3 8 89 9.9 9.98 HVO_0824 "probable glycosyltransferase, type 1" 39.20 1 10 10 44 5.941E7 35.53 39.20 10 21 2323.94 39.20 10 23 352 39.6 5.08 HVO_2958 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit 39.13 1 8 8 25 1.237E7 24.32 31.79 7 12 1122.87 39.13 8 13 368 40.9 4.68 HVO_1778 catalase-peroxidase 39.00 1 18 18 111 2.256E8 97.28 38.30 17 55 5241.71 36.35 17 56 718 80.0 4.31 HVO_2758 50S ribosomal protein L11 38.99 1 5 5 29 1.730E8 31.00 31.45 4 14 1663.04 38.99 5 15 159 16.8 4.04 HVO_0316 A-type ATP synthase subunit A 38.91 1 17 17 201 6.064E8 253.08 37.37 16 101 12430.17 38.91 17 100 586 64.5 4.25 HVO_2969 threonine synthase 38.90 1 11 11 64 9.936E7 76.80 34.37 10 32 4004.08 38.90 11 32 419 44.4 4.49 HVO_0859 FeS assembly ATPase SufC 38.87 1 11 11 104 1.223E8 91.24 36.88 10 51 5781.19 38.87 11 53 301 33.4 4.35 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 38.84 1 10 10 47 4.316E7 30.70 38.84 10 24 2238.62 35.36 9 23 345 36.9 4.68 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 38.73 1 15 15 293 1.499E9 313.04 38.73 15 148 16298.16 38.73 15 145 612 67.3 4.16 HVO_0354 30S ribosomal protein S7 38.73 1 6 6 52 1.086E8 79.34 38.73 6 26 3554.57 38.73 6 26 204 22.6 5.14 HVO_0996 DUF21/CBS domain protein 38.69 1 12 12 40 5.898E7 43.64 38.69 12 20 2243.41 38.69 12 20 367 39.1 4.51 HVO_3002 ABC-type transport system ATP-binding protein 38.65 1 11 11 61 7.430E7 61.77 35.58 9 30 3706.11 38.65 11 31 326 34.7 4.31 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 38.41 1 12 12 67 7.597E7 69.00 38.41 12 33 3654.11 38.41 12 34 453 47.5 4.63 HVO_A0206 CRISPR-associated protein Cas8b 38.35 1 20 20 93 8.424E7 104.13 38.35 20 48 4908.84 35.56 19 45 717 79.3 4.60 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 38.06 1 4 4 12 6.858E6 12.84 31.34 3 5 871.96 38.06 4 7 134 13.9 4.55 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 38.05 1 11 11 92 1.072E8 74.99 38.05 11 47 4130.91 38.05 11 45 473 50.8 4.58 HVO_1921 serine--tRNA ligase 38.04 1 15 15 117 4.266E7 95.61 38.04 15 58 5858.46 34.57 14 59 460 52.0 4.46 HVO_2062 DUF1628 family protein 37.93 1 2 2 11 7.625E6 21.00 37.93 2 11 145 14.8 3.80 HVO_1552 ArsR family transcription regulator 37.86 1 4 4 18 1.841E7 23.60 28.64 3 8 1017.25 37.86 4 10 206 20.8 4.65 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 37.84 1 7 7 26 2.465E7 33.17 37.84 7 13 2141.22 37.84 7 13 259 28.0 4.50 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 37.72 1 7 7 44 4.991E7 57.78 37.72 7 22 2903.12 37.72 7 22 281 30.6 4.59 HVO_1191 proline dehydrogenase 37.63 1 5 5 19 2.846E7 15.70 27.60 4 9 930.73 37.63 5 10 279 31.0 5.02 HVO_1955 aconitate hydratase 37.61 1 17 17 197 5.458E8 232.17 36.54 16 97 12465.97 37.61 17 100 654 70.4 4.45 HVO_2373 30S ribosomal protein S8e 37.60 1 4 4 12 2.468E7 12.64 37.60 4 6 596.30 37.60 4 6 125 13.6 10.48 HVO_1636 conserved hypothetical protein 37.50 1 3 3 5 8.069E6 1.86 37.50 2 2 152.36 29.55 2 3 88 9.4 4.82 HVO_A0049 DUF21/CBS domain protein 37.50 1 11 11 51 6.394E7 61.71 31.92 10 25 2806.08 37.50 11 26 448 48.8 4.31 HVO_1125 cysteine--tRNA ligase 37.45 1 11 11 57 2.923E7 74.85 37.45 11 29 2920.65 37.45 11 28 494 55.2 4.56 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 37.23 1 4 4 26 3.519E7 31.99 37.23 4 13 1630.26 37.23 4 13 188 20.5 4.60 HVO_0233 ribose-phosphate pyrophosphokinase 37.10 1 6 6 38 3.030E7 38.45 37.10 6 19 1884.85 37.10 6 19 283 29.6 4.40 HVO_0467 PhoU/TrkA-C domain protein 37.06 1 12 12 45 2.883E7 60.02 33.33 11 22 2911.65 37.06 12 23 402 43.3 4.49 HVO_1541 glycerol kinase 37.06 1 14 14 77 1.060E8 66.41 33.73 13 37 4252.10 37.06 14 40 510 56.7 4.50 HVO_1018 RecJ domain protein 36.97 1 20 21 163 2.484E8 169.88 35.23 19 82 10023.06 35.55 20 81 633 69.8 4.58 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 36.74 1 10 10 29 1.640E7 40.96 33.70 9 14 1829.39 32.87 9 15 362 39.6 4.82 HVO_1697 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 36.74 1 33 35 343 4.292E8 364.00 35.58 33 168 20269.16 36.74 35 175 1026 111.2 4.54 HVO_1082 homolog to orotate phosphoribosyltransferase 36.67 1 6 6 32 5.021E7 33.58 36.67 6 16 1810.34 36.67 6 16 210 22.3 4.42 HVO_2739 50S ribosomal protein L24e 36.36 1 3 3 12 1.528E7 0.00 36.36 3 6 480.56 36.36 3 6 66 7.5 5.17 HVO_1212 KaiC-type circadian regulator CirA 36.18 1 7 7 29 3.205E7 41.25 36.18 7 15 1709.14 29.27 6 14 246 27.5 4.45 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 36.03 1 7 7 348 7.579E8 446.97 31.99 6 173 21255.08 36.03 7 175 297 32.3 3.98 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 36.01 1 8 9 52 5.064E7 52.27 36.01 9 26 2596.13 36.01 9 26 386 40.0 4.68 HVO_2783 30S ribosomal protein S4 36.00 1 6 6 60 1.289E8 48.71 36.00 6 30 3535.72 36.00 6 30 175 20.1 5.24 HVO_0035 stomatin family protein 35.91 1 7 10 64 3.775E8 77.41 35.91 10 32 3898.75 35.91 10 32 401 43.6 4.65 HVO_0972 DUF1628 family protein 35.84 1 3 3 69 2.517E7 106.27 35.84 3 35 4881.89 35.84 3 34 173 17.7 4.09 HVO_A0428 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 35.80 1 17 17 102 5.096E7 104.27 35.80 17 51 5988.60 35.80 17 51 567 62.4 4.70 HVO_1508 acetolactate synthase large subunit 35.78 1 12 12 342 5.059E8 460.23 35.78 12 171 19998.11 35.78 12 171 587 62.3 4.36 HVO_1130 conserved hypothetical protein 35.75 1 4 4 28 3.645E7 24.79 35.75 4 14 1505.57 35.75 4 14 193 20.1 4.78 HVO_2053 "probable glycosyltransferase, type 1" 35.71 1 11 11 54 9.539E7 65.23 35.71 11 26 3355.87 35.71 11 28 378 41.9 4.67 HVO_1006 ABC-type transport system ATP-binding protein 35.65 1 6 6 18 3.936E7 21.54 35.65 6 9 1135.06 35.65 6 9 317 32.7 4.39 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 35.63 1 19 20 125 1.260E8 102.12 35.63 20 60 6053.35 35.63 20 65 623 62.1 5.30 HVO_C0069 GFO family oxidoreductase 35.49 1 8 8 40 2.437E7 41.71 33.33 7 20 2067.42 35.49 8 20 324 36.0 5.10 HVO_B0371 aldehyde dehydrogenase 35.48 1 7 7 38 3.496E7 57.49 35.48 7 19 2297.50 35.48 7 19 496 52.5 4.39 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 35.43 1 29 29 210 1.607E8 235.54 33.88 28 102 12470.21 35.43 29 108 1033 114.3 4.45 HVO_0829 peptidase S9 family protein 35.36 1 13 13 42 3.685E7 26.70 32.40 12 20 1601.87 35.36 13 22 608 67.4 4.54 HVO_2960 dihydrolipoamide S-acyltransferase 35.32 1 19 19 147 1.859E8 176.45 35.32 19 74 8608.55 35.32 19 73 521 54.9 4.40 HVO_B0093 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 35.28 1 13 13 76 1.088E8 94.23 35.28 13 39 3548.68 35.28 13 37 618 69.1 4.45 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 35.24 1 13 13 79 8.064E7 79.12 33.33 12 38 4383.83 35.24 13 41 525 56.4 4.40 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 35.24 1 11 11 52 4.337E7 63.29 35.24 11 26 3095.90 35.24 11 26 454 48.5 4.46 HVO_1591 conserved hypothetical protein 35.23 1 5 5 32 4.745E7 40.45 35.23 5 16 1965.79 35.23 5 16 264 28.7 5.50 HVO_2047 conserved hypothetical protein 35.14 1 9 9 40 1.504E7 38.78 32.77 8 19 2336.88 35.14 9 21 296 34.2 4.93 HVO_1447 propionyl-CoA carboxylase carboxyltransferase component 35.11 1 15 15 73 8.038E7 82.49 35.11 15 36 4468.23 35.11 15 37 581 63.6 4.70 HVO_0843 conserved hypothetical protein 34.88 1 6 6 22 7.303E7 5.90 34.88 6 10 800.87 34.88 6 12 129 14.7 5.57 HVO_1804 nicotinate phosphoribosyltransferase 34.54 1 10 10 56 9.461E7 56.85 31.44 9 27 3499.74 34.54 10 29 388 41.1 4.60 HVO_0353 30S ribosomal protein S12 34.51 1 5 5 26 7.022E7 25.82 34.51 5 14 1162.46 26.76 4 12 142 15.5 9.91 HVO_0729 inorganic pyrophosphatase 34.46 1 8 8 64 1.797E8 70.38 34.46 8 32 3735.45 34.46 8 32 177 20.4 4.16 HVO_B0111 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 34.41 1 12 12 64 7.159E7 57.29 34.41 12 29 3015.19 34.41 12 35 401 44.2 4.54 HVO_2770 conserved hypothetical protein 34.38 1 8 8 36 6.995E7 34.52 26.25 7 17 2203.30 34.38 8 19 320 35.7 5.15 HVO_0433 F420H2:NADP oxidoreductase 34.23 1 4 4 16 1.183E7 21.07 34.23 4 8 789.91 34.23 4 8 222 23.3 4.72 HVO_2049 "probable glycosyltransferase, type 2" 34.20 1 8 8 29 9.842E7 27.94 34.20 8 14 1482.25 34.20 8 15 307 35.3 5.40 HVO_2690 GFO family oxidoreductase 34.15 1 10 10 51 1.255E8 52.24 34.15 10 26 2375.79 32.24 9 25 366 40.0 4.60 HVO_1871 UPF0447 family protein 34.13 1 13 13 160 7.961E8 114.65 30.74 12 76 8306.87 34.13 13 84 501 56.1 4.59 HVO_1306 chorismate synthase 34.03 1 10 10 70 1.297E8 92.26 34.03 10 35 4168.88 34.03 10 35 385 41.9 4.83 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 34.03 1 29 29 129 7.090E7 106.39 34.03 29 65 5872.24 30.45 27 64 1284 141.2 4.35 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 33.94 1 7 7 35 3.879E7 28.38 33.94 7 17 1536.27 33.94 7 18 386 42.1 4.49 HVO_1692 probable iron-sulfur protein (4Fe-4S) 33.83 1 20 20 223 6.067E8 226.93 33.83 20 111 12078.56 33.83 20 112 733 80.2 4.49 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 33.78 1 11 11 104 1.353E8 109.92 33.78 11 52 5513.85 33.78 11 52 447 48.5 4.56 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 33.70 1 9 9 50 9.956E7 56.24 33.70 9 25 2929.30 33.70 9 25 359 39.4 4.91 HVO_0788 tryptophan synthase beta subunit 33.65 1 9 9 40 2.532E7 33.94 21.09 7 19 2326.06 33.65 9 21 422 45.7 4.65 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 33.56 1 9 9 81 2.855E8 97.67 33.56 9 41 4867.11 33.56 9 40 435 46.9 4.63 HVO_1148 30S ribosomal protein S15 33.55 1 4 4 12 1.554E7 14.35 33.55 4 6 900.30 33.55 4 6 155 17.5 4.91 HVO_2809 succinate dehydrogenase subunit B (iron-sulfur protein) 33.45 1 10 10 70 1.724E8 33.02 29.01 9 35 2825.88 33.45 10 35 293 33.9 5.27 HVO_1707 ABC-type transport system ATP-binding protein (probable substrate iron-III) 33.42 1 7 7 43 1.929E7 34.20 33.42 7 23 1795.50 33.42 7 20 389 41.9 4.40 HVO_0357 ACT domain protein 33.33 1 6 6 26 6.657E7 28.19 33.33 6 13 1645.10 33.33 6 13 189 20.2 4.59 HVO_0041 ornithine carbamoyltransferase 33.11 1 6 6 28 2.570E7 30.43 33.11 6 14 1327.51 33.11 6 14 299 32.7 4.37 HVO_2481 HD family hydrolase 33.08 1 7 9 43 2.782E7 15.98 28.97 8 21 1812.33 33.08 9 22 390 42.7 6.14 HVO_2519 conserved hypothetical protein 32.98 1 9 9 37 2.152E7 49.43 28.27 8 17 2553.81 32.98 9 20 382 40.7 4.35 HVO_2643 NADPH:quinone reductase 32.95 1 8 8 46 4.469E7 38.95 32.95 8 23 2500.34 32.95 7 23 346 37.2 4.55 HVO_B0134 ABC-type transport system ATP-binding protein 32.95 1 5 5 21 1.748E7 13.67 32.95 5 10 836.44 32.95 5 11 258 27.2 4.53 HVO_2646 dihydroxy-acid dehydratase 32.88 1 13 13 61 1.975E8 67.37 32.88 13 31 3492.72 32.88 13 30 584 61.8 4.42 HVO_B0115 fumarylacetoacetase family protein 32.86 1 6 6 17 3.383E7 18.73 32.86 6 9 973.18 20.49 5 8 283 30.3 4.21 HVO_0809 methionine--tRNA ligase 32.84 1 18 18 83 5.566E7 95.51 32.84 18 42 4761.75 32.84 18 41 740 81.9 4.37 HVO_0358 homoserine dehydrogenase 32.81 1 6 6 47 1.493E8 60.57 32.81 6 23 2714.65 32.81 6 24 317 32.4 4.44 HVO_2716 acyl-CoA dehydrogenase 32.81 1 8 8 34 3.383E7 45.28 32.81 8 17 1934.33 32.81 8 17 381 41.3 4.65 HVO_0570 histidine kinase 32.76 1 9 9 66 2.977E7 47.09 32.76 9 33 2699.95 32.76 9 33 351 37.0 5.11 HVO_1025 acetyl-CoA C-acyltransferase 32.64 1 9 9 43 7.196E7 57.34 32.64 9 22 2946.34 32.64 8 21 383 40.7 4.56 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 32.61 1 4 4 18 1.704E7 21.17 32.61 4 9 1048.22 32.61 4 9 184 19.8 5.30 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 32.60 1 10 10 34 2.115E7 35.99 32.60 10 17 1683.95 32.60 10 17 457 48.4 4.35 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 32.41 1 22 22 204 2.384E8 221.94 32.41 22 101 11143.42 32.41 22 103 898 97.7 4.45 HVO_B0117 conserved hypothetical protein 32.21 1 4 5 13 5.930E7 14.61 32.21 4 6 817.00 32.21 5 7 208 23.3 4.58 HVO_1603 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfonate) 32.18 1 5 5 93 2.088E8 117.83 32.18 5 46 3943.78 32.18 5 47 348 37.2 4.35 HVO_0982 NADH dehydrogenase-like complex subunit I 32.03 1 5 5 27 6.821E7 33.39 28.10 4 13 1664.12 32.03 5 14 153 17.7 4.88 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 32.02 1 7 7 67 1.455E8 76.97 32.02 7 33 3959.10 32.02 7 34 431 46.1 4.48 HVO_2813 RimK family protein 32.01 1 11 11 71 3.334E7 83.21 29.80 10 35 4864.29 32.01 11 36 453 49.0 4.73 HVO_0841 cytochrome bc1 complex cytochrome b/c subunit 31.89 1 6 6 45 3.597E8 56.17 27.56 5 22 2578.14 31.89 6 23 254 28.8 5.72 HVO_0549 2-keto-3-deoxygluconate kinase 31.87 1 7 8 22 3.216E7 23.70 28.13 7 10 1731.90 31.87 8 12 320 34.1 4.34 HVO_2430 ABC-type transport system ATP-binding protein (probable substrate glutamine) 31.82 1 6 6 53 6.062E7 62.07 31.82 6 27 2860.47 31.82 6 26 242 26.6 4.88 HVO_0122 phosphoglycerate dehydrogenase 31.79 1 6 6 45 3.776E7 65.06 24.69 5 22 3502.20 31.79 6 23 324 35.3 5.35 HVO_2008 archaeosine synthase 31.62 1 13 13 65 1.104E8 72.97 30.09 12 31 3607.37 31.62 13 34 585 64.9 4.81 HVO_A0331 D-galactonate dehydratase 31.51 1 7 7 34 5.325E7 38.62 31.51 7 18 1600.72 31.51 7 16 384 42.8 4.83 HVO_2993 prepilin peptidase 31.43 1 8 8 29 1.592E7 26.18 31.43 8 15 1504.29 31.43 8 14 350 37.3 4.72 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 31.42 1 19 19 91 9.562E7 61.54 29.84 18 45 4428.56 26.83 18 46 697 74.5 4.13 HVO_B0382 TATA-binding transcription initiation factor 31.38 1 4 4 27 1.387E7 36.10 31.38 4 14 1595.03 31.38 4 13 188 20.1 4.12 HVO_1550 acyl-CoA thioester hydrolase 31.25 1 3 3 11 1.107E7 5.86 24.38 2 4 536.64 31.25 3 7 160 17.6 4.55 HVO_2048 "probable glycosyltransferase, type 1" 31.20 1 9 9 26 3.738E7 22.64 25.91 8 13 1467.52 28.69 8 13 359 40.5 5.30 HVO_0743 probable phosphodiesterase 31.18 1 14 14 68 7.234E7 42.16 29.40 13 34 3443.74 31.18 14 34 449 50.5 4.56 HVO_1168 "probable glycosyltransferase, type 1" 31.16 1 9 9 32 4.383E7 34.42 28.05 8 16 1981.74 30.88 8 16 353 39.1 5.01 HVO_2546 50S ribosomal protein L19e 31.13 1 4 4 62 8.293E7 81.82 31.13 4 31 4621.63 31.13 4 31 151 17.3 9.98 HVO_1370 gamma-glutamyl phosphate reductase 31.08 1 10 10 38 4.728E7 29.64 31.08 10 19 2096.98 25.45 9 19 444 48.1 4.34 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 31.05 1 10 10 52 4.323E7 48.43 31.05 10 27 2647.14 25.20 9 25 496 55.0 4.53 HVO_1198 UspA domain protein 31.03 1 3 4 12 1.539E7 14.12 31.03 4 6 613.42 31.03 4 6 145 15.6 4.75 HVO_0020 ABC-type transport system ATP-binding protein (probable substrate thiamine) 31.02 1 6 6 24 7.419E6 24.18 31.02 6 12 1126.36 31.02 6 12 361 38.3 4.79 HVO_0881 signal peptide peptidase 30.93 1 7 7 33 5.252E7 29.95 30.93 7 16 2001.98 30.93 7 17 333 35.2 4.37 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 30.91 1 7 7 38 1.933E7 26.17 25.45 6 19 1493.27 30.91 7 19 330 36.3 4.35 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 75 1.374E8 91.79 30.84 8 37 3977.63 30.84 8 38 415 44.4 4.41 HVO_0350 DNA-directed RNA polymerase subunit A'' 30.79 1 11 11 67 5.853E7 74.72 30.79 11 34 3128.40 30.79 11 33 419 46.1 4.35 HVO_2225 AstE family protein 30.79 1 6 6 33 5.087E7 36.77 30.79 6 17 1881.17 30.79 6 16 341 36.9 4.53 HVO_2606 PQQ repeat protein 30.66 1 10 11 58 3.446E7 44.42 30.66 11 29 2626.77 30.66 11 29 437 46.9 4.81 HVO_1443 ABC-type transport system ATP-binding protein 30.61 1 7 7 26 2.180E7 29.62 30.61 7 13 1797.01 30.61 7 13 330 36.3 4.70 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 30.54 1 9 9 32 1.886E7 40.31 30.54 9 17 2135.06 26.02 8 15 442 46.9 4.58 HVO_2781 DNA-directed RNA polymerase subunit D 30.50 1 6 6 16 7.199E7 16.43 26.25 5 7 1239.14 30.50 6 9 259 28.1 4.32 HVO_2356 GNAT family acetyltransferase 30.47 1 8 8 36 1.499E7 35.91 30.47 8 18 1623.11 30.47 8 18 407 45.1 4.64 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 30.42 1 6 6 36 2.478E7 36.85 30.42 6 18 1944.46 30.42 6 18 286 31.2 4.54 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 30.41 1 7 7 119 3.590E8 94.92 30.41 7 58 5867.64 30.41 7 61 388 41.9 4.35 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 30.32 1 9 9 35 6.302E7 30.71 30.32 9 17 1858.11 30.32 9 18 376 41.8 4.91 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 30.28 1 9 9 46 6.027E7 35.04 26.61 8 22 2563.35 30.28 9 24 327 36.0 4.73 HVO_B0082 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 30.23 1 11 11 59 4.193E7 64.49 30.23 11 29 3502.85 30.23 11 30 569 62.8 4.30 HVO_1175 DUF2110 family protein 30.22 1 3 3 13 2.150E7 7.31 30.22 3 6 468.97 30.22 3 7 225 24.4 4.63 7428712 "keratin 1, type II, cytoskeletal - human" 30.17 1 0 19 166 3.543E8 208.25 30.17 19 82 11348.58 29.55 18 84 643 65.5 6.35 HVO_2675 histidinol dehydrogenase 30.14 1 8 8 45 1.999E7 36.93 28.74 7 22 2009.55 30.14 8 23 428 45.4 4.50 HVO_C0074 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 30.14 1 14 14 55 2.919E7 53.03 30.14 14 28 3279.56 25.36 13 27 690 75.9 4.79 HVO_2081 pectin lyase domain protein 30.07 1 19 19 86 4.871E7 109.84 26.51 18 42 5343.20 30.07 19 44 1041 109.7 5.34 HVO_2378 ABC-type transport system ATP-binding protein (probable substrate phosphate) 30.07 1 10 10 70 1.798E8 73.76 30.07 10 33 4642.81 30.07 10 37 296 32.6 4.44 HVO_0243 threonine aldolase 29.91 1 7 7 49 2.783E7 57.63 29.91 7 24 3270.78 29.91 7 25 341 35.6 4.55 HVO_1888 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfate/tungstate) 29.82 1 8 8 110 4.648E8 133.15 29.82 8 55 5729.35 29.82 8 55 342 35.9 4.34 HVO_C0075 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 29.75 1 11 11 64 3.827E7 68.92 29.75 11 32 3005.60 29.75 11 32 558 61.3 4.56 HVO_1854 histidine--tRNA ligase 29.47 1 11 11 44 3.448E7 63.04 29.47 11 23 2656.02 29.47 11 21 431 47.1 4.37 HVO_0601 homoserine dehydrogenase 29.43 1 5 5 41 4.844E7 56.68 27.53 4 20 2721.95 29.43 5 21 316 32.2 4.25 HVO_2528 phytoene dehydrogenase (phytoene desaturase) 29.40 1 13 13 93 8.914E7 102.86 29.40 13 46 5004.20 29.40 13 47 500 55.8 4.56 HVO_1894 conserved hypothetical protein 29.35 1 2 2 10 1.162E8 6.78 29.35 2 5 325.77 29.35 2 5 92 10.3 4.67 HVO_2069 RND superfamily permease 29.32 1 15 15 83 3.539E7 91.46 29.32 15 43 4754.52 29.32 15 40 839 89.4 4.42 HVO_1967 glucose-6-phosphate isomerase 29.30 1 8 8 38 3.615E7 48.10 29.30 8 19 2396.00 29.30 8 19 430 45.6 4.40 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 29.17 1 5 5 24 4.319E7 23.84 29.17 5 12 1273.22 29.17 5 12 336 36.0 4.51 HVO_2158 malic enzyme (NADP) 29.16 1 7 13 125 2.276E8 126.12 29.16 13 64 6842.02 28.36 12 61 751 81.4 4.55 HVO_2721 amidophosphoribosyltransferase 29.01 1 6 6 23 2.994E7 30.31 22.92 5 11 1214.02 29.01 6 12 493 53.4 4.78 HVO_2544 30S ribosomal protein S5 28.97 1 4 4 30 1.992E8 40.33 28.97 4 15 2114.09 28.97 4 15 214 23.3 9.29 HVO_C0009 hypothetical protein 28.86 1 1 2 4 4.198E5 0.00 28.86 2 2 46.51 28.86 2 2 149 16.5 6.27 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 28.85 1 7 7 30 4.252E7 24.39 28.85 7 15 1582.37 28.85 7 15 305 33.8 4.74 HVO_2648 phosphoglycerate dehydrogenase 28.84 1 7 7 24 3.209E7 27.77 26.02 6 11 1583.83 28.84 7 13 319 34.2 4.64 HVO_1481 UspA domain protein 28.83 1 3 3 14 1.146E7 11.88 28.83 3 7 643.50 28.83 3 7 163 17.7 4.40 HVO_1504 3-isopropylmalate dehydratase large subunit 28.75 1 10 10 53 7.909E7 71.37 28.75 10 27 3455.27 28.75 10 26 473 51.6 4.55 HVO_2998 homoserine O-acetyltransferase 28.67 1 7 7 33 3.066E7 22.29 28.67 7 16 1570.56 28.67 7 17 415 44.8 4.69 HVO_0874 beta-lactamase domain protein 28.59 1 13 15 88 7.579E7 105.41 27.97 14 44 5948.82 26.56 14 44 640 71.9 5.14 HVO_1917 acyl-CoA synthetase 28.53 1 14 14 80 4.308E7 83.71 28.53 14 41 3892.88 28.53 14 39 666 74.0 4.78 HVO_1727 TATA-binding transcription initiation factor 28.49 1 4 5 21 4.352E7 22.00 28.49 5 11 1353.83 24.73 4 10 186 19.9 4.36 HVO_A0519 MaoC family protein 28.21 1 2 2 2 5.824E5 2.42 28.21 2 2 156 17.5 4.60 HVO_1590 DnaK-type molecular chaperone Hsp70 28.16 1 14 14 88 2.331E8 111.21 28.16 14 44 5030.41 28.16 14 44 625 67.2 4.18 HVO_0307 conserved hypothetical protein 28.08 1 10 11 49 4.898E7 52.37 28.08 11 24 2606.44 28.08 11 25 463 49.0 4.88 HVO_2961 dihydrolipoyl dehydrogenase 28.00 1 8 8 33 2.837E7 34.87 28.00 8 18 1359.19 24.21 7 15 475 49.9 4.41 HVO_A0328 2-keto-3-deoxygluconate kinase 27.99 1 6 7 35 1.631E7 44.64 27.99 7 17 2339.38 27.99 7 18 318 34.0 4.60 HVO_1570 DNA topoisomerase VI subunit A 27.87 1 7 7 42 5.865E7 53.83 25.14 6 20 3311.10 27.87 7 22 366 41.8 4.63 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 27.84 1 11 11 68 6.228E7 78.43 27.84 11 35 3411.68 27.84 11 33 661 71.0 4.35 HVO_A0494 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 27.77 1 8 8 135 1.394E8 151.70 27.77 8 68 6883.55 27.77 8 67 443 47.8 4.21 HVO_0774 "probable glycosyltransferase, type 2" 27.67 1 4 4 14 1.119E7 21.12 27.67 4 7 1168.85 27.67 4 7 300 32.3 6.44 HVO_1034 type IV pilus biogenesis complex ATPase subunit 27.66 1 10 10 31 2.812E7 20.09 27.66 10 15 1318.97 27.66 10 16 564 64.2 4.75 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 27.32 1 3 3 24 1.057E8 22.50 16.49 2 9 1831.23 27.32 3 15 194 20.7 4.12 HVO_1523 agl cluster protein AglQ 27.22 1 5 5 29 1.345E7 16.82 27.22 5 14 992.72 27.22 5 15 371 42.1 6.04 HVO_A0619 conserved hypothetical protein 27.21 1 9 9 34 4.637E7 27.24 27.21 9 17 1630.72 27.21 9 17 452 48.2 4.68 HVO_2431 ABC-type transport system permease protein (probable substrate glutamine) 27.17 1 5 5 29 3.827E7 25.72 17.75 4 13 1663.99 27.17 5 16 276 29.6 5.15 HVO_2070 conserved hypothetical protein 27.02 1 11 11 162 3.621E8 244.45 27.02 11 81 11128.99 26.84 10 81 544 58.1 4.50 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 27.00 1 9 9 67 2.282E8 70.42 27.00 9 33 3558.74 27.00 9 34 400 44.2 4.32 HVO_0109 cysteine desulfurase 27.00 1 9 9 49 2.665E7 56.51 27.00 9 24 2806.40 27.00 9 25 426 46.8 4.56 HVO_0999 DRTGG domain protein 26.98 1 7 7 27 2.046E7 24.25 24.34 6 13 1245.31 26.98 7 14 378 39.8 4.44 HVO_0745 "FtsZ family protein, type III" 26.94 1 4 4 14 7.784E6 11.38 26.94 4 8 599.20 18.33 3 6 360 37.1 4.51 HVO_2773 30S ribosomal protein S2 26.92 1 4 4 38 1.106E8 56.21 26.92 4 19 2730.44 26.92 4 19 260 28.3 4.16 HVO_2080 conserved hypothetical protein 26.85 1 7 7 66 2.011E8 77.23 26.85 7 33 3085.02 26.85 7 33 540 57.0 4.30 HVO_1140 acyl-CoA dehydrogenase 26.84 1 8 8 37 5.506E7 46.17 26.84 8 19 2181.48 26.84 8 18 380 41.2 4.55 HVO_1478 transcription initiation factor TFB 26.81 1 5 8 32 3.094E7 30.08 26.81 8 16 1792.18 26.81 8 16 317 35.7 5.47 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 26.79 1 12 12 95 1.865E8 111.23 26.79 12 48 5902.01 26.79 12 47 586 63.4 4.70 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 26.77 1 4 4 26 6.447E7 17.50 26.77 4 13 1263.39 26.77 4 13 269 28.3 4.49 HVO_0311 A-type ATP synthase subunit I 26.74 1 18 18 185 4.834E8 193.79 26.74 18 92 11273.98 26.74 18 93 733 79.5 4.41 HVO_2016 conserved hypothetical protein 26.42 1 8 8 59 6.506E7 79.77 22.07 7 29 3773.31 26.42 8 30 299 31.2 4.70 HVO_0832 alpha/beta hydrolase fold protein 26.30 1 6 6 89 2.433E8 82.81 26.30 6 44 5544.26 26.30 6 45 308 33.3 4.67 HVO_1711 glucoamylase 26.27 1 30 30 128 8.340E7 144.79 26.27 30 64 7428.02 26.27 30 64 1511 166.1 4.64 HVO_0049 argininosuccinate synthase 26.17 1 10 10 94 2.017E8 72.51 26.17 10 47 4180.64 26.17 10 47 405 44.5 4.34 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 26.16 1 6 6 19 1.721E7 22.26 26.16 6 10 934.27 22.38 5 9 344 37.0 4.55 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 26.10 1 8 8 79 7.691E7 100.84 24.45 7 39 5913.51 26.10 8 40 364 39.3 4.35 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 26.04 1 5 5 14 7.032E6 9.16 26.04 5 7 419.56 26.04 5 7 265 28.7 4.87 HVO_2871 pyridoxal phosphate-dependent aminotransferase 26.00 1 7 7 32 2.338E7 40.89 26.00 7 16 2040.10 26.00 7 16 450 49.1 4.70 HVO_0789 tryptophan synthase alpha subunit 25.99 1 4 4 18 1.219E7 18.00 25.99 4 9 546.60 25.99 4 9 277 29.6 4.21 HVO_1976 protein-export membrane protein SecD 25.95 1 9 9 97 1.524E8 144.98 25.95 9 49 7064.94 25.00 8 48 524 55.0 4.51 HVO_2315 "tritrans,polycis-undecaprenyl-diphosphate synthase" 25.89 1 7 7 30 5.755E6 14.98 25.89 7 15 1383.98 25.89 7 15 309 35.1 4.98 HVO_1387 enoyl-CoA hydratase 25.68 1 7 7 26 4.407E7 17.24 25.68 7 12 1252.53 25.68 7 14 257 27.5 4.51 HVO_1048 phosphoribosylformylglycinamidine synthase 2 25.64 1 11 11 50 3.273E7 60.87 24.64 9 24 2896.20 25.64 11 26 702 72.9 4.18 HVO_1613 "probable glycosyltransferase, type 2" 25.44 1 4 4 38 1.480E8 47.04 25.44 4 19 2490.92 25.44 4 19 228 25.1 4.79 HVO_1593 PAC2 family protein 25.40 1 4 4 14 4.720E7 22.03 25.40 4 7 883.78 25.40 4 7 248 26.6 4.46 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 25.40 1 5 5 33 3.843E7 39.96 25.40 5 16 2109.61 25.40 5 17 252 26.0 4.39 HVO_0146 phosphatidylserine decarboxylase 25.37 1 4 4 16 8.256E6 18.11 25.37 4 8 857.72 25.37 4 8 201 21.7 6.55 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 25.36 1 4 4 25 5.720E7 13.64 25.36 4 12 939.73 25.36 4 13 280 30.1 4.44 HVO_2558 30S ribosomal protein S3 25.33 1 6 6 39 1.305E8 57.54 25.33 6 19 3590.30 25.33 6 20 304 33.4 4.06 HVO_0639 AAA-type ATPase (MoxR subfamily) 25.32 1 6 6 25 1.054E7 21.91 25.32 6 13 1080.91 25.32 6 12 316 34.7 4.89 HVO_2348 GTP cyclohydrolase MptA 25.32 1 7 7 31 1.781E7 27.18 25.32 7 16 1013.26 24.68 6 15 308 33.5 4.68 HVO_1412 diphosphomevalonate decarboxylase 25.31 1 5 5 27 1.043E8 19.61 22.84 4 13 1312.01 25.31 5 14 324 35.4 4.78 HVO_1573 DNA gyrase subunit A 25.29 1 18 18 86 6.722E7 73.22 23.09 17 42 5015.76 25.29 18 44 862 94.8 4.56 HVO_1957 proteasome-activating nucleotidase 25.24 1 7 7 41 7.965E6 32.39 25.24 7 20 1649.75 25.24 7 21 412 45.6 4.48 HVO_1847 oligoendopeptidase PepF 25.21 1 11 11 54 1.810E7 63.14 25.21 11 27 2870.68 25.21 11 27 599 68.5 4.41 HVO_2688 TrmB family transcription regulator 25.21 1 7 7 33 6.660E7 38.27 25.21 7 16 2443.84 25.21 7 17 353 39.3 4.58 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 25.20 1 10 10 29 3.023E7 41.80 23.63 9 14 1891.20 25.20 10 15 512 53.8 4.78 >sp|TRYP_PIG| 25.11 1 5 5 560 1.002E10 788.02 25.11 5 280 37944.03 25.11 5 280 231 24.4 7.18 HVO_0319 A-type ATP synthase subunit D 25.11 1 6 6 24 1.864E7 29.71 25.11 6 12 1629.62 25.11 6 12 235 26.7 4.72 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 25.07 1 5 7 34 5.296E7 43.36 22.45 6 16 2372.94 25.07 7 18 383 41.9 4.21 HVO_0845 conserved hypothetical protein 25.00 1 4 4 24 3.498E7 34.26 25.00 4 12 1509.86 25.00 4 12 276 30.0 4.16 HVO_2551 50S ribosomal protein L5 25.00 1 4 4 36 1.214E8 44.37 25.00 4 18 2859.20 25.00 4 18 172 19.1 4.78 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 25.00 1 7 7 42 3.411E7 50.22 25.00 7 21 2221.87 25.00 7 21 348 38.2 4.32 HVO_0724 ArsA family ATPase 24.94 1 8 8 40 3.066E7 25.51 24.94 8 20 1917.17 24.94 8 20 409 43.9 4.22 HVO_2700 AAA-type ATPase (CDC48 subfamily) 24.93 1 15 16 81 2.144E7 85.85 24.93 16 41 4135.48 24.93 16 40 754 82.8 4.75 HVO_0469 AstE family protein 24.84 1 5 5 18 1.820E7 30.58 24.84 5 9 1259.70 24.84 5 9 318 33.9 5.85 HVO_0717 "cell division protein FtsZ, type I" 24.80 1 7 7 58 8.651E7 80.76 24.80 7 29 4136.10 24.80 7 29 379 39.8 4.40 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 24.71 1 0 3 21 6.654E7 5.06 24.71 3 10 880.58 24.71 3 11 85 10.0 5.94 HVO_0826 peptidase M42 family protein 24.71 1 6 6 20 3.400E7 19.40 24.71 6 10 836.92 24.71 6 10 348 37.7 4.54 HVO_0145 replication factor C small subunit 24.63 1 7 7 20 7.769E6 15.45 24.63 7 10 1046.35 24.63 7 10 341 37.8 4.93 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 24.59 1 8 8 33 3.118E7 28.30 24.59 8 16 1748.22 24.59 8 17 427 45.4 4.56 HVO_B0153 CapB domain protein 24.54 1 10 10 43 2.025E8 53.11 23.26 9 22 2743.97 20.33 9 21 546 60.7 4.87 HVO_2316 serpin family protein 24.50 1 8 8 56 4.449E7 54.79 24.50 8 28 2991.99 24.50 8 28 453 48.7 4.25 HVO_0069 sulfatase 24.47 1 7 7 14 4.335E6 9.02 24.47 7 8 462.45 10.10 4 6 515 57.4 4.35 HVO_2061 "probable glycosyltransferase, type 2" 24.46 1 7 8 41 9.409E7 42.01 23.24 7 21 2355.66 21.79 6 20 413 43.8 4.50 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 24.46 1 6 6 27 4.609E7 26.29 24.46 6 14 1429.72 24.46 6 13 413 45.8 4.45 HVO_A0350 conserved hypothetical protein 24.41 1 5 5 19 1.846E7 17.17 24.41 5 10 820.43 24.41 5 9 213 23.8 9.64 HVO_1300 triosephosphate isomerase 24.30 1 5 5 28 8.498E7 28.59 24.30 5 14 1535.73 24.30 5 14 214 21.3 4.26 HVO_2169 conserved hypothetical protein 24.28 1 6 6 29 5.301E7 21.26 24.28 6 14 1439.76 24.28 6 15 346 36.5 4.39 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 24.22 1 12 12 49 2.378E7 45.61 20.40 11 24 2502.17 24.22 12 25 706 73.3 4.39 HVO_0250 DUF21/CBS domain protein 24.20 1 10 10 87 1.117E8 117.41 24.20 10 44 5676.47 24.20 10 43 471 51.7 4.28 HVO_2300 translation initiation factor aIF-5A 24.19 1 2 2 10 1.946E7 9.00 24.19 2 5 605.00 24.19 2 5 124 14.2 5.22 HVO_A0611 ABC-type transport system periplasmic substrate-binding protein (probable substrate zinc) 24.18 1 4 4 10 5.977E6 9.38 24.18 4 5 434.63 24.18 4 5 335 35.9 4.39 HVO_1751 P-type transport ATPase (probable substrate copper/metal cation) 24.16 1 15 15 77 6.329E7 79.94 24.16 15 39 3771.66 24.16 15 38 861 89.9 4.40 HVO_1916 Kef-type transport system (probable substrate potassium) 24.09 1 11 11 106 9.907E7 116.15 24.09 11 54 6467.33 24.09 11 52 635 66.2 4.63 HVO_0423 conserved hypothetical protein 24.04 1 2 2 3 2.104E7 298.36 24.04 2 3 104 10.7 5.78 HVO_0561 50S ribosomal protein L15e 23.98 1 5 6 46 6.393E8 36.05 23.98 6 23 2516.96 23.98 6 23 196 22.5 11.15 HVO_0600 ACT domain protein 23.73 1 3 3 16 1.653E7 19.46 23.73 3 8 902.53 23.73 3 8 177 19.2 4.44 HVO_2537 conserved hypothetical protein 23.70 1 4 4 14 1.135E7 17.85 23.70 4 7 828.08 23.70 4 7 173 18.9 4.46 HVO_A0339 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 23.70 1 9 9 36 3.365E7 37.95 22.26 8 17 2129.00 23.70 9 19 557 61.2 4.39 HVO_2707 GFO family oxidoreductase 23.66 1 8 8 53 1.026E8 67.67 23.66 8 27 3527.47 23.66 8 26 372 41.0 4.55 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 23.64 1 9 9 27 2.845E7 19.89 23.64 9 14 1169.44 22.56 8 13 461 50.7 4.73 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 23.51 1 7 7 28 8.059E7 24.62 23.51 7 14 1634.41 23.51 7 14 370 41.9 4.48 HVO_2943 dihydroorotate dehydrogenase (quinone) 23.36 1 5 5 23 1.136E7 18.03 23.36 5 12 1487.20 23.36 5 11 351 37.4 4.72 HVO_2456 anthranilate phosphoribosyltransferase 23.26 1 4 4 24 2.945E7 33.86 23.26 4 12 1601.02 23.26 4 12 331 33.8 4.35 HVO_1287 PfpI family protease 23.23 1 3 3 10 1.631E7 13.30 23.23 3 5 625.35 23.23 3 5 198 21.5 4.53 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 23.17 1 6 6 40 1.937E8 26.70 19.31 5 18 2058.52 23.17 6 22 259 29.9 4.36 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 23.12 1 9 9 34 5.016E7 30.61 23.12 9 17 1889.79 23.12 9 17 584 63.3 4.79 HVO_0940 P-type transport ATPase (probable substrate copper/metal cation) 23.07 1 12 12 56 1.321E7 73.89 21.86 11 27 3651.78 23.07 12 29 828 85.9 4.53 HVO_0899 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 22.96 1 7 7 31 6.772E7 39.18 22.96 7 16 1688.55 22.96 7 15 466 49.2 4.20 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 22.96 1 4 4 15 6.990E6 18.77 22.96 4 8 687.83 16.67 3 7 270 29.1 4.35 HVO_2123 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 22.91 1 6 6 28 2.660E7 23.61 22.91 6 14 997.12 20.39 5 14 358 38.8 4.61 HVO_1546 dihydroxyacetone kinase subunit DhaK 22.89 1 9 9 46 5.595E7 47.52 22.89 9 23 2612.91 22.89 9 23 332 34.8 4.22 HVO_1576 NAD-dependent epimerase/dehydratase 22.88 1 1 6 25 1.260E7 21.78 22.88 6 12 1371.95 22.88 6 13 306 33.9 4.51 HVO_1571 DNA topoisomerase VI subunit B 22.81 1 12 12 78 5.259E7 94.61 20.43 11 39 4589.26 22.81 12 39 798 87.4 4.73 HVO_1831 ferredoxin (2Fe-2S) 22.80 1 4 4 56 1.542E8 60.97 22.80 4 28 3156.94 22.80 4 28 193 20.4 3.98 HVO_1176 conserved hypothetical protein 22.71 1 5 5 20 5.470E7 7.46 22.71 5 10 934.49 22.71 5 10 251 27.7 5.11 HVO_1459 ThuA family protein 22.69 1 3 3 16 1.874E7 19.46 22.69 3 8 975.84 22.69 3 8 238 26.8 4.67 HVO_B0161 respiratory nitrate reductase iron-sulfur subunit 22.58 1 2 2 2 0.000E0 0.00 22.58 2 2 217 22.6 4.83 HVO_2435 peptidase M24 family protein 22.55 1 5 5 15 1.140E7 16.28 22.55 5 7 799.62 22.55 5 8 368 40.0 4.53 HVO_1540 glycerol-3-phosphate dehydrogenase subunit C 22.48 1 8 9 83 2.400E8 98.39 22.48 9 41 4822.09 22.48 9 42 436 48.6 4.61 HVO_1049 PHP domain protein 22.47 1 3 3 12 5.535E6 6.62 22.47 3 6 523.25 22.47 3 6 227 24.0 5.41 HVO_1076 sugar nucleotidyltransferase 22.36 1 5 5 17 1.648E7 13.11 22.36 5 8 832.19 22.36 5 9 322 35.8 4.20 HVO_1529 glycosyltransferase AglG 22.36 1 8 8 62 1.200E8 59.40 22.36 8 31 3427.55 22.36 8 31 313 35.8 4.59 HVO_B0118 SMC-like protein Sph2 22.36 1 11 11 47 4.791E7 45.78 22.36 11 23 2593.34 22.36 11 24 644 73.8 4.41 HVO_0058 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 22.30 1 9 9 34 8.492E7 42.45 22.30 9 17 2060.20 21.17 8 17 444 50.2 4.84 HVO_0704 "probable glycosyltransferase, type 2" 22.22 1 4 4 18 1.398E7 10.13 22.22 4 9 972.40 22.22 4 9 261 28.4 5.30 HVO_0447 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate/phosphonate) 22.13 1 3 3 132 2.257E8 71.34 22.13 3 68 2086.38 20.40 2 64 348 36.5 3.75 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 22.12 1 5 5 13 1.598E7 12.41 19.03 4 6 749.71 19.03 4 7 226 25.5 4.25 HVO_2467 NADPH:quinone reductase 22.12 1 5 5 15 1.016E7 19.93 22.12 5 8 744.91 16.82 4 7 321 33.0 4.51 HVO_1354 DNA mismatch repair protein MutS 22.07 1 11 11 32 1.207E7 30.27 19.14 9 15 1407.60 22.07 11 17 580 62.1 4.56 HVO_1523_A glycosyltransferase AglE 22.04 1 6 6 16 2.578E7 8.71 14.80 5 6 895.65 22.04 6 10 304 33.8 7.08 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 21.98 1 7 7 24 3.059E7 21.82 21.98 7 12 1119.80 21.98 7 12 373 40.2 4.44 HVO_1513 conserved hypothetical protein 21.93 1 3 3 7 3.160E7 5.57 11.40 2 4 283.13 18.42 2 3 228 25.1 5.07 HVO_1228 halocyanin 21.92 1 12 12 142 2.075E8 167.06 21.92 12 70 7763.56 21.92 12 72 821 83.7 4.17 HVO_0893 methylmalonyl-CoA mutase subunit A 21.91 1 8 9 26 4.414E7 26.54 21.91 9 13 1302.00 20.32 8 13 566 63.1 4.36 HVO_0104 DNA repair and recombination protein RadA 21.87 1 5 5 18 2.567E7 16.35 16.62 4 8 1404.19 21.87 5 10 343 37.3 4.64 HVO_2533 conserved hypothetical protein 21.73 1 5 5 42 3.671E7 49.88 21.73 5 21 2598.78 21.73 5 21 336 35.1 4.39 HVO_1658 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 21.67 1 3 3 7 6.059E6 2.24 21.67 3 4 276.97 21.67 3 3 180 19.6 5.24 HVO_0766 Hsp20-type molecular chaperone 21.60 1 2 2 3 2.943E4 4.80 21.60 2 3 162 17.7 4.39 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 21.52 1 7 7 26 1.784E7 32.43 21.52 7 13 1392.87 21.52 7 13 474 53.4 4.59 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 21.46 1 2 2 8 6.039E6 10.65 21.46 2 4 456.51 21.46 2 4 219 22.4 4.06 HVO_1944 conserved hypothetical protein 21.39 1 6 6 18 2.085E7 21.14 21.39 6 9 945.08 21.39 6 9 416 43.0 4.22 HVO_2267 hypothetical protein 21.30 1 7 7 36 2.533E7 28.63 21.30 7 18 1635.94 21.30 7 18 385 44.3 4.56 HVO_0480 phosphoglycerate kinase 21.20 1 7 7 22 1.554E7 25.53 21.20 7 11 1170.45 21.20 7 11 401 43.6 4.37 HVO_A0551 acyl-CoA synthetase 21.19 1 9 9 43 2.147E7 56.32 21.19 9 22 2135.92 19.52 8 21 538 59.6 4.65 HVO_2665 HpcH/HpaI aldolase family protein 21.13 1 5 5 10 6.388E6 8.25 17.36 4 5 424.67 18.87 4 5 265 28.3 4.50 HVO_B0228 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 21.13 1 5 5 42 2.120E7 52.76 21.13 5 21 1894.92 21.13 5 21 459 50.2 4.36 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 21.05 1 3 3 18 3.708E7 24.98 21.05 3 9 1261.25 21.05 3 9 190 20.6 4.30 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 21.04 1 6 6 38 9.016E7 43.70 21.04 6 19 2095.07 21.04 6 19 347 36.8 4.93 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 20.94 1 3 3 24 1.518E7 31.27 20.94 3 12 1512.92 20.94 3 12 277 30.6 4.30 HVO_0445 ABC-type transport system permease protein (probable substrate phosphate/phosphonate) 20.87 1 4 4 17 6.725E7 20.57 20.87 4 8 934.99 20.87 4 9 321 35.5 4.81 HVO_B0200 malate synthase 20.87 1 5 5 27 8.443E7 33.78 20.87 5 13 1284.14 20.87 5 14 436 48.3 4.30 HVO_1675 magnesium transport protein CorA 20.80 1 5 5 18 1.499E7 20.54 20.80 5 9 1149.43 11.93 4 9 327 37.2 4.55 HVO_1164 HD family hydrolase 20.74 1 5 5 28 2.675E7 24.77 20.74 5 14 1390.41 20.74 5 14 270 29.8 4.87 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 20.71 1 6 7 18 1.070E7 9.63 16.79 4 8 1035.72 18.93 6 10 280 30.0 4.92 HVO_1545 dihydroxyacetone kinase subunit DhaL 20.69 1 3 4 10 1.529E7 3.15 20.69 4 5 482.31 20.69 4 5 232 24.8 4.48 HVO_A0496 UspA domain protein 20.69 1 5 5 32 2.075E7 38.68 20.69 5 16 1772.40 20.69 5 16 290 31.4 4.60 HVO_1528 glycosyltransferase AglI 20.68 1 5 5 20 2.734E7 19.77 20.68 5 10 1003.03 20.68 5 10 295 32.8 4.72 HVO_0552 DNA mismatch repair protein MutS 20.67 1 13 13 37 3.100E7 32.55 20.67 13 19 1671.07 17.75 12 18 924 99.2 4.65 HVO_2495 DUF106 family protein 20.66 1 8 8 102 1.872E8 100.71 20.66 8 52 5734.60 20.66 8 50 305 33.5 4.58 HVO_B0101 IclR family transcription regulator 20.62 1 4 4 10 5.198E6 7.46 20.62 4 5 555.59 20.62 4 5 257 28.6 5.02 HVO_1156 conserved hypothetical protein 20.43 1 2 2 3 1.981E6 0.00 20.43 2 3 328 34.2 4.31 HVO_2617 TrkA-C domain protein 20.35 1 7 7 32 3.098E7 43.66 20.35 7 17 1679.66 20.35 7 15 403 42.0 4.96 HVO_C0054 hypothetical protein 20.35 1 5 5 34 3.925E7 37.90 20.35 5 17 2222.02 20.35 5 17 344 37.5 4.70 HVO_2670 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 20.23 1 17 18 67 6.204E7 47.91 19.75 17 33 3071.45 20.23 18 34 1058 113.8 4.69 HVO_2801 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 20.21 1 4 4 34 3.141E7 32.24 20.21 4 17 1470.27 20.21 4 17 287 31.4 4.48 HVO_2082 conserved hypothetical protein 20.20 1 5 5 17 6.123E7 16.94 20.20 5 9 760.82 18.69 4 8 396 40.9 4.50 HVO_0959 conserved hypothetical protein 20.18 1 3 3 10 9.525E6 9.46 20.18 3 5 505.19 20.18 3 5 228 25.7 4.84 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 20.13 1 2 11 57 7.003E7 43.82 20.13 11 28 2715.50 20.13 11 29 472 51.6 5.16 HVO_1530 dolichyl-monophosphooligosaccharide--protein glycotransferase AglB 20.11 1 18 18 113 1.958E8 133.56 19.54 17 56 5980.14 20.11 18 57 1054 113.6 4.56 HVO_2163 ABC-type transport system ATP-binding protein (homolog to LolDCE lipoprotein release factor) 20.08 1 3 3 13 1.397E7 12.24 20.08 3 6 563.88 20.08 3 7 249 26.7 6.90 HVO_0466 citrate (si)-synthase 20.05 1 6 6 42 5.342E7 58.68 20.05 6 21 2290.55 20.05 6 21 379 41.8 4.55 HVO_1558 cytochrome P450 20.05 1 8 8 31 1.401E7 22.98 20.05 8 15 1204.36 20.05 8 16 434 48.4 4.92 HVO_1572 DNA gyrase subunit B 20.03 1 9 9 36 1.615E7 38.59 20.03 9 19 1518.74 15.49 7 17 639 71.2 4.83 HVO_0285 probable metalloprotease 20.00 1 7 7 27 2.927E7 35.01 20.00 7 14 1818.94 20.00 7 13 390 42.1 4.98 HVO_0310 A-type ATP synthase subunit H 20.00 1 2 2 3 1.024E7 7.00 20.00 2 3 110 12.5 4.03 HVO_1597 conserved hypothetical protein 20.00 1 2 2 8 4.952E6 11.52 20.00 2 4 534.50 20.00 2 4 130 13.7 4.45 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 19.96 1 18 18 110 7.772E7 141.91 18.48 17 54 6806.72 19.96 18 56 1082 117.2 4.32 HVO_0573 endonuclease IV 19.93 1 3 3 29 1.100E7 37.14 19.93 3 14 1524.15 19.93 3 15 291 31.4 4.44 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 19.93 1 5 5 20 2.298E7 15.71 19.93 5 10 950.54 19.93 5 10 286 30.8 4.46 HVO_0048 argininosuccinate lyase 19.88 1 7 7 44 2.839E7 46.56 17.42 6 16 4206.13 19.88 7 28 488 50.8 4.53 HVO_1257 AAA-type ATPase (MoxR subfamily) 19.82 1 6 6 16 1.558E7 12.64 19.82 6 8 764.42 19.82 6 8 338 37.4 4.67 HVO_1184 DUF1511 family protein 19.79 1 7 7 22 7.598E7 20.58 17.15 6 10 1381.13 19.79 7 12 379 40.3 4.22 HVO_2384 CBS domain protein 19.74 1 5 5 22 1.327E8 32.01 19.74 5 11 1594.42 19.74 5 11 380 42.5 5.01 HVO_1241 SCO1/SenC/PrrC family protein 19.73 1 2 2 10 1.502E7 11.86 19.73 2 5 420.09 19.73 2 5 223 24.6 4.45 HVO_1901 translation initiation factor aIF-2 gamma subunit 19.71 1 7 7 39 4.304E7 33.42 19.71 7 20 1668.77 19.71 7 19 411 43.9 4.36 HVO_B0060 precorrin-4 C11-methyltransferase 19.71 1 2 2 2 3.697E6 68.24 19.71 2 2 279 29.7 4.22 HVO_1172 NAD-dependent epimerase/dehydratase 19.68 1 5 5 15 2.465E7 23.34 16.51 4 7 1039.64 19.68 5 8 315 34.9 4.34 HVO_2454 anthranilate synthase component I 19.66 1 7 7 26 1.404E7 30.00 19.66 7 13 1261.53 19.66 7 13 524 55.9 4.56 HVO_0046 putative glutamate--argW ligase 19.59 1 5 5 18 1.228E7 13.15 19.59 5 8 1015.45 19.59 5 10 291 31.9 4.87 HVO_1294 GMC family oxidoreductase 19.58 1 7 7 21 2.912E7 21.59 19.58 7 11 918.78 19.58 6 10 526 56.7 4.94 HVO_0002 signal peptidase I 19.51 1 3 3 14 4.085E7 11.87 19.51 3 7 738.58 19.51 3 7 287 30.3 4.60 HVO_0138 tyrosine--tRNA ligase 19.51 1 5 5 26 1.646E7 26.27 19.51 5 13 1285.11 17.38 4 13 328 36.1 4.34 HVO_2020 DUF502 family protein 19.48 1 3 3 14 3.183E7 21.98 19.48 3 7 1154.05 19.48 3 7 267 29.4 4.35 HVO_0711 conserved hypothetical protein 19.44 1 4 4 16 4.355E7 15.05 14.35 3 7 1037.06 19.44 4 9 216 23.1 3.81 HVO_1327 AAA-type ATPase (CDC48 subfamily) 19.43 1 7 8 29 8.995E6 30.26 19.43 8 15 1426.15 19.43 8 14 736 78.1 4.88 HVO_2059 NAD-dependent epimerase/dehydratase 19.35 1 5 5 24 2.245E7 22.81 19.35 5 12 1220.36 19.35 5 12 310 34.1 4.40 HVO_0854 DNA double-strand break repair ATPase Rad50 19.26 1 11 11 38 1.007E7 39.21 19.26 11 19 2012.72 19.26 11 19 893 100.0 4.58 HVO_1601 ABC-type transport system ATP-binding protein (probable substrate sulfonate) 19.19 1 3 3 5 1.369E7 324.50 19.19 3 5 271 29.0 4.36 HVO_2419 hydroxymethylglutaryl-CoA synthase 19.10 1 6 6 26 2.440E7 15.45 19.10 6 13 1093.73 19.10 6 13 445 50.1 4.64 HVO_0865 FkbM family methyltransferase 19.05 1 4 4 11 2.282E7 13.54 19.05 4 5 690.44 19.05 4 6 252 27.7 5.49 HVO_2057 sugar nucleotidyltransferase 19.05 1 5 5 16 1.744E7 18.60 19.05 5 8 860.08 19.05 5 8 357 37.8 4.44 HVO_0944 ba3-type terminal oxidase subunit II 18.99 1 3 3 29 7.995E7 31.30 18.99 3 14 1729.15 18.99 3 15 179 19.4 4.28 HVO_2209 probable branched-chain amino acid dehydrogenase E1 component alpha subunit 18.97 1 5 5 18 2.766E7 14.26 18.97 5 10 903.98 18.97 5 8 348 38.7 4.70 HVO_1245 probable disulfide bond formation protein 18.94 1 4 4 38 7.839E7 32.47 18.94 4 19 2039.81 18.94 4 19 227 24.2 4.50 HVO_B0021 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 18.94 1 9 9 66 2.793E7 69.52 18.94 9 33 3913.07 18.94 9 33 644 70.6 4.56 HVO_0958 conserved hypothetical protein 18.92 1 2 2 6 2.424E7 7.37 18.92 2 3 345.46 18.92 2 3 148 15.5 10.26 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 18.86 1 5 5 18 1.920E7 19.73 18.86 5 9 1021.42 18.86 5 9 403 41.1 4.73 HVO_B0106 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 18.85 1 5 5 26 2.407E7 30.79 18.85 5 13 1656.08 18.85 5 13 488 52.6 4.13 HVO_0519 replication protein A 18.84 1 6 6 27 1.668E7 34.63 18.84 6 14 1219.35 14.29 5 13 483 51.0 4.13 HVO_0697 PAC2 family protein 18.82 1 2 2 8 1.506E7 15.68 18.82 2 4 616.49 18.82 2 4 255 27.4 4.08 HVO_1517 dolichyl-phosphate hexosyltransferase AglJ 18.81 1 4 4 25 1.197E8 11.32 18.81 4 12 1259.33 18.81 4 13 303 33.2 4.82 HVO_1979 tRNA pseudouridine synthase Pus10 18.74 1 6 6 25 1.955E7 23.74 18.74 6 12 1200.87 18.74 6 13 427 46.9 4.39 HVO_0685 DUF3100 family protein 18.71 1 5 5 26 4.284E7 34.12 18.71 5 13 1749.29 18.71 5 13 294 30.1 5.29 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 18.66 1 5 5 18 2.609E7 27.17 18.66 5 9 1193.50 18.66 5 9 343 38.4 4.94 HVO_0902 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 18.65 1 4 4 12 7.294E6 15.18 18.65 4 6 681.27 18.65 4 6 252 27.3 4.65 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 18.62 1 5 5 26 6.908E7 28.24 18.62 5 13 1336.18 18.62 5 13 349 37.0 4.70 HVO_1660 DisA-N domain protein 18.59 1 4 4 16 2.316E7 21.74 18.59 4 8 1232.27 18.59 4 8 269 28.9 4.73 HVO_1496 phosphotransferase system component I 18.58 1 7 7 53 2.971E7 47.41 18.58 7 27 2578.41 18.58 7 26 565 60.3 4.21 HVO_1914 acetyl-CoA C-acyltransferase 18.57 1 5 5 35 1.167E7 28.84 15.92 4 17 1711.54 18.57 5 18 377 39.9 4.41 HVO_1165 mechanosensitive channel protein MscS 18.54 1 4 4 27 3.994E7 32.78 18.54 4 13 1582.66 18.54 4 14 302 32.6 4.91 HVO_B0194 conserved hypothetical protein 18.53 1 6 6 26 2.234E7 21.37 17.26 5 12 1315.50 18.53 6 14 394 42.7 5.35 HVO_0209 acyl-CoA dehydrogenase 18.35 1 5 5 14 7.116E6 19.77 18.35 5 7 817.48 18.35 5 7 387 42.4 4.93 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 18.35 1 3 3 10 7.466E6 9.82 18.35 3 5 339.14 18.35 3 5 267 29.1 4.63 HVO_2529 probable oxidoreductase (short-chain dehydrogenase family) 18.26 1 2 2 2 4.258E6 97.32 18.26 2 2 230 23.6 4.72 HVO_B0345 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 18.25 1 5 5 10 6.953E6 11.55 18.25 5 6 342.81 8.99 3 4 378 41.2 4.84 HVO_2427 replication factor C large subunit 18.24 1 7 7 42 2.610E7 55.50 18.24 7 21 2350.72 18.24 7 21 488 53.4 4.67 HVO_0123 signal recognition particle 54K protein 18.06 1 7 7 64 2.202E7 45.05 15.91 6 32 2963.17 18.06 7 32 465 50.9 4.50 HVO_0699 translation initiation factor aIF-2 alpha subunit 18.05 1 4 4 16 1.839E7 14.35 18.05 4 8 741.84 18.05 4 8 266 29.5 4.46 HVO_1123 thioredoxin-disulfide reductase 18.05 1 5 5 21 1.222E7 16.00 14.90 4 7 1469.22 18.05 5 14 349 37.3 4.32 HVO_0203 replication factor C small subunit 18.04 1 5 5 21 2.804E7 31.39 18.04 5 11 1263.64 18.04 5 10 327 36.2 4.51 HVO_0583 conserved hypothetical protein 18.04 1 3 3 16 9.993E6 21.83 18.04 3 8 869.92 18.04 3 8 194 21.2 4.42 HVO_2001 tRNA-guanine(15) transglycosylase 18.02 1 5 5 27 1.103E7 25.35 18.02 5 13 1123.58 18.02 5 14 516 56.3 4.59 HVO_0054 glycine--tRNA ligase 18.01 1 7 7 32 7.720E7 38.78 15.66 6 15 2094.40 18.01 7 17 594 64.9 4.21 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 17.97 1 5 5 21 2.926E7 17.83 14.43 4 8 1197.03 17.97 5 13 395 42.4 4.54 HVO_0530 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 17.94 1 4 4 58 1.425E8 56.70 17.94 4 30 2430.83 17.94 4 28 457 48.1 4.11 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 17.82 1 4 4 17 6.292E6 5.37 17.82 4 9 654.13 10.06 3 8 348 36.7 4.69 HVO_2500 transport protein (probable substrate cationic amino acids) 17.78 1 9 9 46 4.419E7 57.25 17.78 9 23 2597.17 17.78 9 23 748 78.6 4.61 HVO_0324 arginine--tRNA ligase 17.72 1 9 9 30 8.643E6 30.72 17.72 9 15 1375.12 17.72 9 15 587 65.0 4.35 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 17.57 1 7 7 24 1.530E7 12.76 17.57 7 12 992.56 17.57 7 12 626 67.6 4.65 HVO_1936 F420-0:gamma-glutamyl ligase 17.53 1 4 4 8 1.466E7 4.57 17.53 4 4 358.15 17.53 4 4 251 27.4 4.68 HVO_0417 metal-dependent carboxypeptidase 17.33 1 7 7 34 8.699E7 30.61 17.33 7 17 2028.25 17.33 7 17 502 57.3 4.42 HVO_0721 PHP domain protein 17.32 1 3 3 10 3.172E7 7.43 17.32 3 5 696.88 17.32 3 5 254 28.2 5.97 HVO_2981 uracil phosphoribosyltransferase 17.26 1 3 3 8 1.667E7 8.21 9.73 2 3 780.42 17.26 3 5 226 24.5 4.49 HVO_A0627 conserved hypothetical protein 17.23 1 4 4 18 1.733E7 19.45 17.23 4 9 951.28 17.23 4 9 354 38.1 4.70 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 17.14 1 5 5 21 1.149E7 18.71 17.14 5 11 1007.49 17.14 5 10 420 45.0 4.86 HVO_0008 aspartate kinase 17.09 1 4 4 24 5.470E7 23.84 17.09 4 11 1319.11 17.09 4 13 392 41.7 4.46 HVO_0306 conserved hypothetical protein 17.09 1 5 5 27 1.394E7 30.70 17.09 5 14 1502.73 14.29 4 13 392 42.1 4.30 HVO_2913 superoxide dismutase (Mn) 17.09 1 0 3 32 2.817E8 38.89 17.09 3 16 2131.93 17.09 3 16 199 22.3 4.48 HVO_1547 isoleucine--tRNA ligase 17.07 1 13 13 47 5.104E7 43.17 17.07 12 25 2208.17 15.53 11 22 1043 117.9 4.30 HVO_2173 DUF1616 family protein 17.07 1 5 5 20 1.401E7 16.42 17.07 5 10 880.33 17.07 5 10 334 36.6 4.92 HVO_1235 creatininase 17.05 1 4 4 12 1.330E7 4.97 17.05 4 6 450.50 17.05 4 6 264 29.2 4.84 HVO_B0323 oxidoreductase domain protein 17.02 1 2 2 2 6.543E5 0.00 17.02 2 2 382 43.2 4.65 HVO_A0475 superoxide dismutase (Mn) 17.00 1 0 3 32 2.817E8 38.89 17.00 3 16 2131.93 17.00 3 16 200 22.4 4.45 HVO_2541 protein translocase subunit SecY 16.97 1 7 7 57 1.258E8 44.85 16.97 7 28 3155.75 16.97 7 29 489 52.3 6.81 HVO_2618 TrkA-C domain protein 16.97 1 6 6 28 3.729E7 21.73 16.97 6 14 1312.80 16.97 6 14 501 50.6 4.49 HVO_0590 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase 16.90 1 3 3 12 1.374E7 15.92 16.90 3 6 407.37 16.90 3 6 355 35.6 4.30 HVO_0931 UspA domain protein 16.90 1 1 2 2 5.659E6 115.38 16.90 2 2 142 15.2 4.46 HVO_1268 conserved hypothetical protein 16.88 1 3 3 4 4.580E6 3.46 12.66 2 2 169.31 12.66 2 2 237 26.4 5.21 HVO_1563 conserved hypothetical protein 16.80 1 2 2 8 3.191E7 9.39 16.80 2 4 519.35 16.80 2 4 125 13.8 11.02 HVO_B0292 ABC-type transport system periplasmic substrate-binding protein (probable substrate glycerol-3-phosphate) 16.77 1 5 5 26 1.739E7 33.27 16.77 5 13 1101.22 16.77 5 13 489 52.6 4.36 HVO_0043 acetylornithine aminotransferase 16.67 1 4 4 21 2.643E7 29.55 12.96 3 10 1384.87 16.67 4 11 378 39.7 4.67 HVO_0400 conserved hypothetical protein 16.67 1 2 2 6 2.639E6 8.18 16.67 2 3 453.77 16.67 2 3 126 13.9 4.68 HVO_2056 "probable epimerase (homolog to dTDP-4-dehydrorhamnose 3,5-epimerase)" 16.67 1 3 3 12 5.956E6 2.84 10.90 2 3 1042.99 16.67 3 9 156 18.3 4.55 HVO_0541 aconitate hydratase 16.63 1 13 13 63 2.907E7 69.59 16.63 13 32 3661.95 16.63 13 31 938 102.1 4.40 HVO_0763 YphA family protein 16.57 1 1 3 23 4.244E7 10.81 9.71 2 10 1633.28 16.57 3 13 175 18.9 6.54 HVO_A0548 YphA family protein 16.57 1 1 3 22 2.889E7 10.81 9.71 2 10 1434.29 16.57 3 12 175 18.9 6.54 HVO_2945 valine--tRNA ligase 16.55 1 10 10 40 3.326E7 19.53 15.06 9 21 1914.24 12.87 9 19 870 98.9 4.36 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 16.52 1 4 4 9 5.107E6 10.38 16.52 4 5 544.32 11.41 3 4 333 36.7 4.56 HVO_B0324 conserved hypothetical protein 16.48 1 5 6 14 4.980E6 15.01 15.59 5 7 435.30 14.48 5 7 449 48.0 4.58 HVO_0309 S-adenosylmethionine-dependent methyltransferase 16.43 1 3 3 12 1.093E7 10.39 16.43 3 6 620.88 16.43 3 6 207 23.7 4.97 HVO_1038 uracil-DNA glycosylase superfamily protein 16.35 1 3 3 11 2.780E7 5.82 16.35 3 6 433.17 16.35 3 5 208 22.7 4.61 HVO_B0102 glycosidase family protein 16.34 1 5 5 13 5.096E6 4.22 13.52 4 5 847.12 16.34 5 8 355 38.7 4.75 HVO_0787 indole-3-glycerol-phosphate synthase 16.33 1 2 2 7 4.035E6 7.12 16.33 2 4 223.53 16.33 2 3 251 26.7 4.44 HVO_2072 S-layer glycoprotein 16.32 1 6 6 2212 2.545E9 2889.25 16.32 6 1107 94471.19 16.32 6 1105 827 85.1 3.65 HVO_2160 conserved hypothetical protein 16.30 1 22 22 454 9.417E8 552.66 16.08 21 229 27255.97 16.30 22 225 2257 232.7 3.92 HVO_2872 conserved hypothetical protein 16.16 1 6 6 16 6.725E6 12.80 16.16 6 8 812.94 16.16 6 8 458 50.8 4.81 HVO_1264 conserved hypothetical protein 16.13 1 3 3 16 1.923E7 22.18 16.13 3 8 1209.41 16.13 3 8 217 23.4 4.22 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 16.07 1 4 11 42 6.693E7 26.93 13.95 10 20 2015.04 16.07 11 22 473 51.2 5.05 HVO_2190 gluconate permease 16.07 1 8 8 57 6.972E7 66.38 16.07 8 29 3376.79 16.07 7 28 473 49.0 4.96 HVO_C0042 helicase domain protein 15.93 1 17 17 67 5.272E7 68.18 15.93 17 33 3659.59 15.93 17 34 1274 144.4 4.67 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 15.87 1 4 4 8 7.043E6 4.06 11.38 3 4 231.84 8.73 3 4 378 39.8 4.45 HVO_B0264 phosphoglycerate dehydrogenase 15.84 1 3 3 6 4.866E6 6.79 15.84 3 3 286.19 15.84 3 3 322 34.8 4.88 HVO_1531 UDP-glucose 6-dehydrogenase 15.81 1 6 6 18 1.864E7 17.85 15.81 6 8 948.56 15.81 6 10 430 45.9 4.50 HVO_2302 ubiquinone biosynthesis protein UbiB 15.77 1 8 8 26 2.860E7 31.58 15.77 8 13 1850.50 15.77 8 13 558 63.0 4.69 HVO_1760 ABC-type transport system ATP-binding protein (probable substrate iron-III) 15.70 1 3 4 18 2.367E7 2.32 15.70 4 9 605.82 15.70 4 9 293 32.4 4.58 HVO_0220 ATP-dependent DNA helicase MCM 15.67 1 9 9 24 9.058E6 27.56 15.67 9 12 1358.30 15.67 9 12 702 78.8 4.73 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 15.67 1 3 3 21 4.419E6 26.58 15.67 3 11 1214.48 15.67 3 10 268 27.9 4.87 HVO_2790 ATP-binding protein Mrp 15.61 1 3 3 12 1.021E7 19.39 15.61 3 6 667.19 15.61 3 6 346 36.8 4.50 HVO_A0451 transport protein (probable substrate arsenite/antimonite) 15.60 1 9 9 42 4.409E7 55.64 15.60 9 21 2994.37 15.60 9 21 641 68.3 4.60 HVO_2630 conserved hypothetical protein 15.56 1 4 4 24 9.273E6 23.76 15.56 4 12 1732.16 15.56 4 12 302 32.9 4.48 HVO_2607 PQQ repeat protein 15.52 1 4 4 16 9.717E6 12.86 15.52 4 8 638.12 15.52 4 8 406 42.3 4.86 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 15.49 1 5 5 16 1.760E7 12.14 15.49 5 8 827.31 15.49 5 8 439 47.2 4.59 HVO_A0092 acyl-CoA dehydrogenase 15.49 1 5 5 14 7.365E6 10.98 15.49 5 7 744.28 15.49 5 7 381 42.2 4.83 HVO_0061 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 15.47 1 3 3 15 1.486E7 17.69 10.03 2 7 851.37 15.47 3 8 349 38.8 6.18 HVO_0420 transducer protein MpcT 15.47 1 4 4 12 9.077E6 16.34 15.47 4 6 594.75 15.47 4 6 543 57.1 4.12 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 15.41 1 3 3 12 8.369E6 8.37 15.41 3 6 452.37 15.41 3 6 305 34.1 4.91 HVO_0953 conserved hypothetical protein 15.36 1 8 8 26 1.247E7 20.68 15.36 8 13 1206.20 15.36 8 13 612 65.9 4.64 HVO_0158 TATA-binding transcription initiation factor 15.34 1 2 3 9 1.540E7 10.99 15.34 3 5 726.15 11.64 2 4 189 20.3 4.22 HVO_2732 FixC family protein 15.34 1 5 6 20 1.495E7 12.49 13.72 5 10 775.63 14.26 5 10 554 59.8 4.83 HVO_1975 protein-export membrane protein SecF 15.33 1 3 3 45 1.771E8 44.07 11.15 2 20 2528.96 15.33 3 25 287 30.4 4.55 HVO_1110 ABC-type transport system periplasmic substrate-binding protein (probable substrate cobalamin) 15.18 1 3 3 29 4.202E7 43.31 15.18 3 15 2370.19 15.18 3 14 382 39.6 4.25 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 15.13 1 4 4 26 1.013E7 38.28 15.13 4 13 1481.99 15.13 4 13 423 43.9 4.31 HVO_B0182 deoxyhypusine synthase 15.12 1 4 4 15 1.371E7 8.96 15.12 4 8 605.63 15.12 4 7 324 35.6 4.30 HVO_0415 repair helicase 15.10 1 7 7 25 2.115E7 27.80 15.10 7 13 1263.60 15.10 7 12 616 69.6 4.70 HVO_1579 uridine phosphorylase 15.07 1 3 3 10 2.087E7 6.47 15.07 3 5 437.27 15.07 3 5 272 29.0 4.64 HVO_1380 methylmalonyl-CoA mutase subunit A 15.05 1 5 5 20 1.346E7 27.87 15.05 5 10 1074.79 15.05 5 10 558 61.9 4.41 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 15.05 1 3 3 12 3.815E7 15.61 15.05 3 6 758.87 15.05 3 6 299 32.0 4.53 HVO_2286 conserved hypothetical protein 15.03 1 4 4 17 9.539E6 24.79 15.03 4 9 1121.23 10.91 3 8 559 62.3 4.35 HVO_1169 "probable glycosyltransferase, type 1" 14.95 1 4 4 7 3.886E6 3.66 12.23 3 3 272.43 14.95 4 4 368 40.8 4.73 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 14.88 1 3 3 8 1.709E7 6.11 14.88 3 4 314.43 7.44 2 4 363 39.7 4.25 HVO_B0057 precorrin-3B C17-methyltransferase 14.83 1 2 2 4 3.167E7 6.45 14.83 2 4 344 36.3 4.31 HVO_1291 fumarylacetoacetase family protein 14.81 1 2 2 10 4.538E7 7.91 14.81 2 5 330.69 14.81 2 5 243 26.3 4.55 HVO_1023 conserved hypothetical protein 14.76 1 3 3 16 1.803E7 17.36 14.76 3 8 830.92 14.76 3 8 271 30.2 4.63 HVO_2297 deoxyhypusine synthase 14.76 1 3 3 9 4.502E6 10.37 14.76 3 5 334.94 14.76 3 4 359 38.6 4.59 HVO_1014 cox-type terminal oxidase subunit II 14.68 1 2 2 37 3.339E7 39.07 14.68 2 19 1918.98 14.68 2 18 252 27.7 4.59 HVO_1373 acyl-CoA dehydrogenase 14.62 1 4 4 13 9.696E6 5.07 14.62 4 6 574.23 14.62 4 7 383 42.5 4.61 HVO_0161 ATP phosphoribosyltransferase 14.59 1 3 3 16 1.057E7 17.47 14.59 3 8 1184.46 14.59 3 8 281 30.4 4.60 HVO_1867 lysine--tRNA ligase 14.59 1 5 5 18 9.689E6 20.07 14.59 5 9 802.23 14.59 5 9 555 62.1 4.46 HVO_1589 molecular chaperone DnaJ 14.55 1 5 5 17 3.104E7 6.34 9.87 3 7 1040.73 14.55 5 10 385 41.9 4.97 HVO_0304 electron transfer flavoprotein alpha subunit 14.51 1 3 3 23 7.711E7 16.61 11.36 2 10 1022.46 14.51 3 13 317 33.5 4.18 HVO_1710 alpha amylase 14.48 1 8 9 41 3.406E7 26.97 13.88 8 20 2148.74 14.48 9 21 677 75.0 4.45 HVO_2150 halocyanin 14.48 1 2 2 18 2.415E7 28.96 14.48 2 9 1237.47 14.48 2 9 373 37.7 4.42 HVO_0240 Lrp/AsnC family transcription regulator 14.47 1 2 2 6 4.672E6 6.75 14.47 2 3 327.36 14.47 2 3 152 16.9 4.39 HVO_A0159 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 14.47 1 4 4 12 1.321E7 11.85 14.47 4 6 453.44 14.47 4 6 387 42.7 4.44 HVO_2165 ABC-type transport system permease protein (homolog to LolDCE lipoprotein release factor) 14.45 1 4 4 14 1.475E7 14.98 14.45 4 7 609.07 14.45 4 7 429 44.4 5.12 HVO_0452 leucine--tRNA ligase 14.41 1 11 11 49 3.501E7 56.56 14.41 11 25 2978.78 14.41 11 24 958 109.5 4.37 HVO_2383 DNA repair and recombination protein RadB 14.41 1 2 2 2 5.866E6 3.44 14.41 2 2 229 24.6 5.02 HVO_1340 "probable glycosyltransferase, type 1" 14.40 1 4 4 14 7.564E6 14.29 14.40 4 7 878.58 14.40 4 7 375 41.0 4.42 HVO_B0026 probable oxidoreductase (short-chain dehydrogenase family) 14.40 1 2 2 6 3.710E6 8.57 14.40 2 3 267.32 14.40 2 3 257 26.7 4.55 HVO_0694 probable phosphoribosyltransferase 14.35 1 3 3 13 3.800E6 13.58 9.28 2 6 557.24 14.35 3 7 237 27.0 4.32 HVO_1040 DnaJ domain protein 14.25 1 5 5 18 3.159E6 20.76 14.25 5 9 929.30 14.25 5 9 379 38.3 9.45 HVO_2187 CHP01210 family protein 14.17 1 4 4 17 2.946E7 11.68 14.17 4 8 844.91 14.17 4 9 360 40.0 4.58 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 14.17 1 3 3 16 4.000E6 13.46 9.84 2 6 864.65 14.17 3 10 254 26.9 4.42 HVO_0629 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 14.16 1 4 4 14 2.233E7 12.56 14.16 4 7 720.53 14.16 4 7 339 36.7 8.40 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 14.12 1 0 8 41 7.003E7 27.66 14.12 8 20 1973.93 14.12 8 21 432 48.1 5.02 HVO_1577 conserved hypothetical protein 14.12 1 2 2 10 1.059E7 12.65 14.12 2 5 551.99 14.12 2 5 177 19.4 4.74 HVO_0154 conserved hypothetical protein 14.09 1 2 2 9 9.322E6 7.76 14.09 2 4 350.41 14.09 2 5 149 15.8 4.31 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 14.01 1 7 7 62 3.070E8 56.47 14.01 7 31 2970.25 14.01 7 31 357 40.3 4.40 HVO_1065 Mrp-type sodium/proton antiporter system subunit E 14.00 1 2 2 14 3.410E7 19.31 14.00 2 7 562.36 14.00 2 7 200 21.7 4.68 HVO_2381 UPF0272 family protein 14.00 1 4 4 21 1.650E7 23.48 14.00 4 10 1059.68 14.00 4 11 493 52.3 4.88 HVO_2951 tryptophan--tRNA ligase 13.99 1 5 5 18 6.009E6 3.49 13.99 5 9 499.93 13.99 5 9 529 59.1 4.53 HVO_0896 acyl-CoA synthetase 13.89 1 5 5 20 6.821E6 23.30 13.89 5 10 965.09 13.89 5 10 540 59.8 4.56 HVO_2530 homolog to phosphoribosylamine--glycine ligase 13.86 1 4 4 13 7.635E6 10.43 7.05 3 6 528.08 13.86 4 7 440 49.8 4.70 HVO_2172 conserved hypothetical protein 13.77 1 7 7 34 2.276E7 44.38 13.77 7 17 2192.50 13.77 7 17 741 75.2 4.27 HVO_2798 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 13.73 1 4 4 69 3.655E8 69.00 13.73 4 34 3302.42 13.73 4 35 437 44.6 3.95 21961227 Keratin 6B [Homo sapiens] 13.65 1 0 7 50 1.377E8 64.11 13.65 7 25 3256.22 13.65 7 25 564 60.0 8.00 HVO_1137 ion channel pore / TrkA domain protein 13.59 1 5 5 16 8.736E6 17.48 13.59 5 8 813.11 13.59 5 8 552 58.7 4.56 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 13.50 1 5 5 42 1.422E7 36.91 13.50 5 21 2163.68 13.50 5 21 526 57.2 4.31 HVO_A0087 fumarylacetoacetase family protein 13.49 1 2 2 6 1.982E7 2.43 13.49 2 3 338.61 13.49 2 3 289 32.0 4.21 HVO_2496 adenylate kinase 13.46 1 2 2 10 2.641E7 12.26 13.46 2 5 646.80 13.46 2 5 208 23.1 4.25 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 13.41 1 6 6 17 8.314E6 20.41 11.83 5 8 979.14 13.41 6 9 634 66.1 4.54 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 13.37 1 9 9 34 2.734E7 37.76 13.37 9 17 1820.42 13.37 9 17 838 89.1 4.65 HVO_A0283 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 13.33 1 5 5 13 2.434E7 16.24 13.33 5 7 849.13 11.56 4 6 450 49.1 4.51 HVO_0237 UPF0761 family protein 13.26 1 5 5 30 4.305E7 47.87 13.26 5 15 2835.48 13.26 5 15 445 46.7 5.14 HVO_1554 TraB family protein 13.19 1 5 5 18 2.046E7 21.23 13.19 5 9 962.18 13.19 5 9 561 59.0 4.58 HVO_2712 3'-5' RNA ligase 13.17 1 4 4 9 5.940E6 2.59 13.17 4 5 234.37 7.00 3 4 486 53.4 4.92 HVO_0044 acetylglutamate kinase 13.15 1 3 3 10 3.983E6 14.39 13.15 3 5 804.13 13.15 3 5 327 33.2 4.49 HVO_C0072 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 13.13 1 3 3 12 4.493E6 11.46 13.13 3 6 543.08 13.13 3 6 297 31.6 6.39 HVO_0396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 13.06 1 3 3 14 2.038E7 17.10 13.06 3 7 1048.39 13.06 3 7 360 39.2 5.01 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 13.05 1 1 8 36 1.087E8 31.31 13.05 8 18 2126.46 13.05 8 18 590 62.4 8.06 HVO_1112 ABC-type transport system ATP-binding protein (probable substrate cobalamin) 13.03 1 4 4 16 1.267E7 25.24 13.03 4 8 1069.00 13.03 4 8 476 49.4 4.55 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 13.01 1 4 4 14 1.975E7 15.44 13.01 4 7 636.60 13.01 4 7 438 46.4 4.58 HVO_0951 hypothetical protein 12.91 1 4 4 24 2.604E7 28.64 12.91 4 12 1647.53 12.91 4 12 333 38.1 4.69 HVO_B0154 receiver/sensor box histidine kinase 12.91 1 12 12 42 2.024E7 40.89 11.22 11 20 2146.71 12.91 12 22 1301 144.1 4.39 HVO_2203 conserved hypothetical protein 12.88 1 3 3 21 9.488E6 23.84 12.88 3 11 1133.13 12.88 3 10 264 28.4 4.20 HVO_0630 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 12.86 1 2 2 10 4.080E7 12.96 12.86 2 5 598.98 12.86 2 5 311 33.1 4.98 HVO_1868 conserved hypothetical protein 12.85 1 2 2 10 9.980E6 9.43 12.85 2 5 430.09 12.85 2 5 179 20.0 5.38 HVO_A0306 4-aminobutyrate aminotransferase 12.81 1 4 4 14 8.633E6 12.93 12.81 4 7 700.24 12.81 4 7 445 47.6 4.68 HVO_0674 4-phosphopantoate--beta-alanine ligase 12.80 1 2 2 2 7.063E5 2.27 12.80 2 2 250 26.5 4.73 HVO_0892 ABC-type transport system periplasmic substrate-binding protein (probable substrate copper) 12.79 1 7 7 21 1.428E7 22.52 12.79 7 10 1050.79 11.70 6 11 641 67.1 4.70 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 12.79 1 3 3 9 2.240E7 7.73 7.74 2 4 312.98 12.79 3 5 297 31.3 4.36 HVO_1615 conserved hypothetical protein 12.75 1 3 3 7 4.811E6 8.06 12.75 3 3 379.60 12.75 3 4 251 28.4 4.59 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 12.75 1 4 4 9 1.121E7 8.64 12.75 4 5 331.08 9.35 3 4 353 36.7 4.65 HVO_1981 hypothetical protein 12.69 1 2 2 70 6.143E6 75.09 12.69 2 35 4765.23 12.69 2 35 197 20.3 4.01 HVO_1199 acyl-CoA dehydrogenase 12.63 1 3 3 8 4.926E6 6.92 12.63 3 4 285.11 12.63 3 4 380 41.5 4.64 HVO_B0038A D-xylonate dehydratase 12.62 1 1 6 44 3.035E8 21.90 11.41 5 22 1881.44 8.98 5 22 412 45.5 4.55 HVO_A0547 DUF1028 family protein 12.61 1 3 3 8 4.235E6 8.84 12.61 3 4 406.49 12.61 3 4 333 35.2 4.16 HVO_1260 von Willebrand factor type A domain protein 12.59 1 5 5 11 6.611E6 13.85 6.97 4 5 594.37 12.59 5 6 818 85.1 4.65 HVO_A0432 conserved hypothetical protein 12.59 1 0 4 9 4.343E6 4.16 10.62 3 4 358.10 12.59 4 5 405 44.5 5.24 HVO_A0406 conserved hypothetical protein 12.59 1 0 4 9 4.343E6 4.16 10.62 3 4 358.10 12.59 4 5 405 44.4 5.30 HVO_B0059 cobalt-precorrin 5A hydrolase 12.58 1 3 3 18 1.138E7 17.05 12.58 3 9 884.08 12.58 3 9 326 34.5 4.51 HVO_1236 acyl-CoA synthetase 12.52 1 5 5 18 6.827E6 11.75 12.52 5 9 736.20 12.52 5 9 535 59.1 4.60 HVO_1242 conserved hypothetical protein 12.50 1 5 5 20 9.686E6 16.29 12.50 5 10 710.85 12.50 5 10 432 47.1 4.75 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 12.45 1 5 5 18 1.578E7 10.64 12.45 5 9 764.38 12.45 5 9 482 50.6 4.31 HVO_1103 conserved hypothetical protein 12.42 1 3 3 10 8.585E7 9.67 8.82 2 4 717.07 12.42 3 6 306 31.2 4.74 HVO_A0522 acetyl-CoA C-acyltransferase 12.40 1 3 3 12 9.280E6 17.23 12.40 3 6 544.34 12.40 3 6 387 39.2 4.77 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 12.27 1 3 3 18 1.628E7 27.98 12.27 3 9 1033.42 12.27 3 9 383 42.0 4.49 HVO_0564 ABC-type transport system periplasmic substrate-binding protein (probable substrate maltose) 12.27 1 4 4 24 3.494E7 37.07 12.27 4 12 1739.39 12.27 4 12 432 46.8 4.18 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 12.23 1 1 6 29 1.248E8 29.59 12.23 6 15 1927.57 8.87 5 14 564 60.2 8.00 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 12.21 1 4 4 12 7.219E6 16.82 12.21 4 6 699.13 12.21 4 6 475 49.3 4.49 HVO_B0266 glutamate dehydrogenase (NAD) 12.18 1 5 5 14 1.608E7 11.87 12.18 5 7 868.71 12.18 5 7 435 47.3 4.63 HVO_1735 conserved hypothetical protein 12.12 1 7 7 19 6.743E6 18.10 12.12 7 9 956.34 12.12 7 10 660 75.7 4.50 HVO_2521 DUF21/CBS domain protein 12.03 1 3 3 12 3.768E7 17.37 12.03 3 6 1035.22 12.03 3 6 349 38.4 4.42 HVO_1985 ABC-type transport system ATP-binding protein 11.99 1 3 3 11 1.560E7 11.55 11.99 3 6 466.93 11.99 3 5 317 35.0 4.54 HVO_1374 acyl-CoA synthetase 11.93 1 6 6 20 5.635E7 22.50 9.40 5 10 1259.60 11.93 6 10 553 61.1 4.50 HVO_2448 probable oxidoreductase (aldo-keto reductase family protein) 11.93 1 4 4 12 1.500E7 8.53 6.12 2 5 750.81 11.93 4 7 327 36.5 4.94 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 11.88 1 0 6 32 1.248E8 35.57 11.88 6 16 2069.69 11.88 6 16 564 60.0 8.00 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 11.87 1 4 4 9 6.961E6 9.38 11.87 4 5 418.66 8.71 3 4 379 41.7 4.83 HVO_A0426 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 11.87 1 3 3 7 4.697E6 5.41 11.87 3 4 239.11 9.20 2 3 337 36.8 5.16 HVO_0988 NADH dehydrogenase-like complex subunit N 11.86 1 4 4 23 5.790E7 30.59 11.86 4 12 1466.26 9.88 3 11 506 52.2 4.64 HVO_1281 "probable glycosyltransferase, type 1" 11.76 1 3 3 8 1.233E6 4.86 11.76 3 4 442.13 11.76 3 4 357 38.7 5.87 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 11.76 1 3 3 8 1.199E7 9.98 11.76 3 4 383.48 11.76 3 4 357 39.8 4.41 HVO_2881 DUF4013 family protein 11.76 1 3 3 8 3.773E7 7.48 9.02 2 4 481.93 11.76 3 4 255 27.5 4.79 HVO_1031 thioredoxin-disulfide reductase 11.70 1 3 3 8 1.179E7 2.51 11.70 3 4 323.76 11.70 3 4 342 37.4 4.46 4557890 keratin 5 [Homo sapiens] 11.69 1 0 7 32 1.087E8 29.51 11.69 7 16 1984.23 11.69 7 16 590 62.4 8.06 HVO_2882 DUF4013 family protein 11.67 1 2 2 6 2.640E7 1.81 11.67 2 3 216.13 11.67 2 3 240 25.4 4.55 HVO_B0143 receiver/sensor box histidine kinase 11.56 1 4 4 9 9.533E6 4.46 5.19 3 4 384.43 11.56 4 5 597 66.0 4.41 HVO_A0380 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 11.55 1 5 5 25 1.220E7 16.91 9.06 4 11 1007.61 11.55 5 14 563 62.8 4.70 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 11.50 1 5 5 20 9.823E6 25.14 9.50 4 10 1229.85 11.50 5 10 600 65.3 4.68 HVO_2122 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 11.41 1 3 3 10 2.596E7 11.40 7.88 2 4 725.36 11.41 3 6 368 40.0 4.63 HVO_A0550 receiver/sensor box histidine kinase 11.41 1 8 9 21 4.677E6 19.46 10.40 8 10 1208.13 11.41 9 11 885 95.9 4.46 HVO_1623 conserved hypothetical protein 11.41 1 2 2 6 7.133E6 8.76 11.41 2 3 399.07 11.41 2 3 298 32.8 4.56 HVO_0195 ribose-5-phosphate isomerase 11.30 1 2 2 6 5.965E6 5.19 11.30 2 3 271.61 11.30 2 3 230 23.2 4.54 HVO_1371 glutamate 5-kinase 11.30 1 3 3 12 9.980E6 12.50 11.30 3 6 734.88 11.30 3 6 301 32.0 4.25 HVO_1129 conserved hypothetical protein 11.28 1 2 3 13 1.189E7 13.90 10.00 2 6 598.74 11.28 3 7 390 43.0 4.44 HVO_0424 ABC-type transport system ATP-binding protein 11.26 1 5 5 17 8.230E6 14.67 8.11 4 8 859.65 11.26 5 9 604 67.2 4.49 HVO_1870 probable metalloprotease 11.26 1 6 6 36 3.920E7 29.29 11.26 6 18 2178.81 11.26 6 18 595 62.0 4.84 HVO_1368 probable metallo-beta-lactamase family hydrolase 11.24 1 3 3 20 1.734E7 20.16 11.24 3 10 972.43 11.24 3 10 267 29.3 4.49 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 11.20 1 0 4 24 9.294E7 29.59 11.20 4 12 1754.61 11.20 4 12 384 42.4 5.40 HVO_2692 ABC-type transport system ATP-binding protein (probable substrate sugar) 11.14 1 3 3 16 1.339E7 14.09 11.14 3 8 850.08 11.14 3 8 395 43.3 4.37 HVO_1983 malate synthase 11.09 1 2 2 5 1.384E7 4.52 11.09 2 2 71.46 11.09 2 3 433 48.0 4.42 HVO_2888 homolog to elongator complex protein ELP3 11.09 1 3 3 4 3.431E6 0.00 9.64 2 2 139.64 5.09 2 2 550 62.6 5.01 HVO_1098 diaminopimelate decarboxylase 11.08 1 4 4 10 5.374E6 3.88 8.43 3 5 421.16 6.51 3 5 415 44.4 5.02 HVO_2536 CHP00300 family protein 11.06 1 2 2 10 1.204E7 5.68 11.06 2 5 338.26 11.06 2 5 416 44.8 4.51 HVO_A0624 P-type transport ATPase (probable substrate zinc/cadmium) 11.06 1 6 6 36 2.621E7 44.96 11.06 6 18 2176.67 11.06 6 18 895 92.5 4.42 HVO_1240 conserved hypothetical protein 11.05 1 4 4 36 8.468E6 33.85 11.05 4 18 1798.98 11.05 4 18 353 37.4 4.49 HVO_0907 cox-type terminal oxidase subunit I 11.02 1 4 4 44 1.403E8 32.80 11.02 4 22 2136.83 11.02 4 22 599 65.7 5.11 HVO_1542 conserved hypothetical protein 11.02 1 2 2 28 1.225E8 44.94 11.02 2 14 2157.24 11.02 2 14 354 36.1 5.48 HVO_1058 TrkA domain protein 11.01 1 4 4 11 9.088E6 13.77 11.01 4 6 499.67 11.01 4 5 445 47.7 4.35 HVO_1657 phosphoribosylamine--glycine ligase 10.98 1 5 5 21 2.217E7 16.44 8.18 4 10 1055.85 10.98 5 11 428 45.5 4.20 HVO_0792 3-dehydroquinate synthase type II 10.97 1 3 3 10 1.064E7 9.79 10.97 3 5 428.82 10.97 3 5 392 43.1 4.44 HVO_A0553 adenosylcobyric acid synthase 10.94 1 3 3 7 5.011E6 7.76 10.94 3 3 252.29 10.94 3 4 512 52.6 4.50 HVO_1510 2-isopropylmalate synthase 10.91 1 4 4 19 4.298E7 14.11 10.91 4 8 911.77 10.91 4 11 440 47.7 4.82 HVO_2318 "tritrans,polycis-undecaprenyl-diphosphate synthase" 10.89 1 2 2 2 9.165E6 164.33 10.89 2 2 202 23.1 4.63 HVO_A0240 ISH9-type transposase ISHvo3 10.87 1 1 2 2 6.139E6 2.05 10.87 2 2 276 31.1 9.48 HVO_1424 conserved hypothetical protein 10.86 1 3 3 8 7.020E6 9.85 10.86 3 4 392.89 10.86 3 4 359 40.9 4.60 HVO_B0029 xylose dehydrogenase (NADP) 10.77 1 3 3 22 1.060E7 30.59 10.77 3 11 1288.62 10.77 3 11 325 34.7 4.39 HVO_2967 conserved hypothetical protein 10.73 1 2 2 4 3.066E6 4.31 10.73 2 2 205.91 10.73 2 2 205 22.4 5.66 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 10.64 1 1 6 30 1.248E8 31.36 10.64 6 15 1997.92 10.64 6 15 564 60.0 8.00 HVO_0986 NADH dehydrogenase-like complex subunit L 10.62 1 7 7 46 1.864E8 35.05 10.62 7 23 2294.49 10.62 7 23 678 71.7 6.14 HVO_2324 SSSF family transport protein 10.62 1 5 5 22 1.036E8 26.18 10.62 5 11 1116.04 10.62 5 11 499 52.9 6.60 HVO_0975 homolog to membrane-bound mannosyltransferase 10.62 1 5 5 18 1.999E7 20.29 10.62 5 9 1049.91 10.62 5 9 584 62.8 4.97 HVO_1959 histidine kinase 10.54 1 2 2 6 2.544E6 582.16 10.54 2 6 294 31.4 4.59 HVO_0175 DNA polymerase sliding clamp 10.53 1 2 2 8 3.390E7 7.96 10.53 2 4 595.75 10.53 2 4 247 26.7 4.39 HVO_0602 3-dehydroquinate dehydratase 10.53 1 2 2 3 1.857E6 1.76 10.53 2 3 247 27.3 4.51 HVO_1932 2-D-hydroxyacid dehydrogenase 10.39 1 3 3 5 3.023E6 5.53 10.39 3 3 167.91 7.14 2 2 308 33.0 4.60 HVO_0683 conserved hypothetical protein 10.39 1 2 2 3 1.464E6 154.37 10.39 2 3 231 25.4 4.54 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 10.37 1 2 2 6 9.810E6 6.54 10.37 2 3 247.94 10.37 2 3 241 26.1 4.58 HVO_B0233 alpha-L-arabinofuranosidase 10.37 1 5 5 22 9.890E6 19.72 10.37 5 11 993.73 10.37 5 11 511 57.5 4.39 HVO_2524 phytoene synthase 10.32 1 2 2 6 6.238E6 1.72 10.32 2 3 167.27 10.32 2 3 339 38.3 4.82 HVO_A0458 ParA domain protein 10.31 1 2 2 4 6.383E6 5.79 10.31 2 2 169.64 10.31 2 2 291 32.2 4.79 HVO_1134 conserved hypothetical protein 10.30 1 6 6 20 1.092E7 24.02 10.30 6 10 952.89 10.30 6 10 757 80.6 4.35 HVO_0818 threonine synthase 10.28 1 4 4 11 1.269E7 6.21 10.28 4 5 502.02 10.28 4 6 389 40.8 4.31 HVO_2800 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 10.28 1 3 3 11 2.395E7 7.06 10.28 3 5 599.04 10.28 3 6 253 27.6 4.42 HVO_2879 ornithine cyclodeaminase 10.24 1 2 2 4 1.013E7 324.10 10.24 2 4 332 34.6 4.45 HVO_A0286 DUF187 family protein 10.21 1 2 2 3 2.753E6 7.76 10.21 2 3 382 42.2 4.75 HVO_1866 uridylate kinase 10.13 1 2 2 8 7.710E6 9.98 10.13 2 4 559.97 10.13 2 4 237 24.6 4.42 386849 keratin type II 10.12 1 0 5 24 1.248E8 28.56 10.12 5 12 1569.28 10.12 5 12 563 59.9 7.94 HVO_1398 ABC-type transport system permease protein (probable substrate sugar) 10.08 1 3 3 14 9.344E6 15.26 10.08 3 7 809.77 10.08 3 7 367 38.4 6.57 HVO_1862 probable metalloprotease 10.03 1 2 2 4 3.436E6 7.45 10.03 2 4 379 40.9 5.21 HVO_0388 homolog to ribonuclease R 10.02 1 4 4 38 5.563E6 30.90 10.02 4 19 1798.21 10.02 4 19 439 50.3 4.73 HVO_0246 ArsR family transcription regulator 10.00 1 2 2 8 6.826E6 6.52 10.00 2 4 282.09 10.00 2 4 320 31.9 4.41 HVO_B0144 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 9.98 1 3 3 18 7.545E6 15.24 9.98 3 9 844.27 9.98 3 9 401 44.3 4.40 HVO_A0586 sugar nucleotidyltransferase 9.98 1 3 3 9 1.004E7 7.44 9.98 3 4 430.76 9.98 3 5 411 43.7 4.69 HVO_0655 NAD-dependent epimerase/dehydratase 9.97 1 3 3 7 6.075E6 5.89 7.04 2 3 504.71 9.97 3 4 341 36.9 4.74 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 9.96 1 2 2 4 3.025E6 2.88 9.96 2 2 192.75 9.96 2 2 261 27.0 4.44 HVO_0995 conserved hypothetical protein 9.86 1 3 3 8 5.892E6 3.84 9.86 3 4 297.23 9.86 3 4 345 35.9 4.96 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 9.85 1 2 2 8 3.835E6 11.60 9.85 2 4 313.63 9.85 2 4 406 43.1 4.60 HVO_B0025 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 9.83 1 3 3 8 2.458E6 4.10 9.83 3 4 288.44 9.83 3 4 346 37.2 4.53 HVO_2600 methionyl aminopeptidase 9.80 1 3 3 8 7.380E6 11.55 9.80 3 4 473.58 9.80 3 4 296 32.3 4.41 HVO_0014 ATP-dependent DNA helicase Hel308a 9.79 1 5 5 21 7.752E6 30.40 9.79 5 11 1526.60 9.79 5 10 827 90.3 4.67 HVO_1372 pyrroline-5-carboxylate reductase 9.73 1 2 2 9 8.095E6 9.72 9.73 2 5 555.07 9.73 2 4 257 26.8 4.01 HVO_1261 conserved hypothetical protein 9.70 1 4 4 14 8.143E6 9.23 9.70 4 7 732.56 9.70 4 7 598 62.6 4.64 HVO_0214 L-lactate dehydrogenase 9.69 1 2 2 8 4.449E7 11.15 9.69 2 4 531.08 9.69 2 4 320 34.5 4.49 31559815 keratin 25B [Homo sapiens] 9.62 1 2 3 5 7.632E6 1.71 5.34 2 2 161.37 9.62 3 3 468 51.8 4.96 HVO_1462 "1,4-dihydroxy-2-naphthoate octaprenyltransferase" 9.62 1 3 3 9 3.113E6 5.31 6.41 2 4 339.04 9.62 3 5 312 32.7 8.28 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 9.57 1 2 2 6 9.145E6 5.28 9.57 2 3 215.55 9.57 2 3 324 33.6 3.99 HVO_0215 iron-sulfur protein (4Fe-4S) 9.52 1 5 5 24 2.094E7 19.05 9.52 5 12 1035.20 9.52 5 12 704 78.2 4.58 HVO_A0524 3-hydroxyacyl-CoA dehydrogenase 9.52 1 3 3 8 2.813E6 7.47 9.52 3 4 503.45 9.52 3 4 294 31.3 4.45 HVO_1972 GNAT family acetyltransferase 9.48 1 2 2 12 7.119E6 9.53 9.48 2 6 688.00 9.48 2 6 211 23.3 6.02 HVO_1337 rpa-associated protein 9.47 1 4 4 21 8.822E6 17.63 9.47 4 11 721.29 9.47 4 10 623 64.8 3.68 HVO_A0160 sensor box histidine kinase 9.46 1 4 4 14 6.100E6 19.44 9.46 4 7 782.73 9.46 4 7 708 76.5 4.79 HVO_A0576 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 9.43 1 3 3 16 3.031E7 20.81 9.43 3 8 1003.08 9.43 3 8 435 45.5 4.17 HVO_A0305 methylmalonate-semialdehyde dehydrogenase 9.41 1 3 3 14 1.677E7 17.31 9.41 3 7 792.19 9.41 3 7 489 52.1 4.59 HVO_0330 DUF502 family protein 9.35 1 2 2 12 1.441E7 13.57 9.35 2 6 540.39 9.35 2 6 214 23.3 4.67 HVO_B0064 conserved hypothetical protein 9.35 1 2 2 42 1.980E8 53.33 9.35 2 21 2562.64 9.35 2 21 278 28.1 5.47 HVO_0687 M20 family amidohydrolase 9.23 1 3 3 14 1.036E7 18.14 9.23 3 7 784.99 9.23 3 7 444 47.5 4.58 HVO_0401 UspA domain protein 9.21 1 2 2 6 2.118E7 10.96 9.21 2 3 549.10 9.21 2 3 152 16.4 4.79 HVO_0981 NADH dehydrogenase-like complex subunit H 9.17 1 3 3 14 7.328E7 16.08 9.17 3 7 843.96 9.17 3 7 349 36.9 5.19 HVO_B0328 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 9.17 1 4 4 19 4.771E6 22.37 9.17 4 10 950.14 6.30 3 9 698 78.6 4.63 HVO_1258 conserved hypothetical protein 9.12 1 3 3 11 3.926E6 6.43 9.12 3 4 590.20 9.12 3 7 307 31.8 4.23 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 9.01 1 2 2 8 4.849E6 11.04 9.01 2 4 741.05 9.01 2 4 344 39.1 4.73 HVO_2602 transport protein (probable substrate zinc/cadmium) 9.00 1 2 2 14 8.846E6 17.91 9.00 2 7 663.67 9.00 2 7 311 33.3 4.77 HVO_1585 acyl-CoA synthetase 8.98 1 3 3 11 3.858E6 15.48 8.98 3 6 424.21 8.98 3 5 668 74.1 4.48 HVO_2418 conserved hypothetical protein 8.97 1 4 4 15 1.041E7 12.92 8.97 4 7 785.61 8.97 4 8 892 94.6 4.16 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 8.94 1 4 4 15 1.941E7 13.39 6.91 3 7 876.96 8.94 4 8 492 52.1 4.83 HVO_B0267 peptidase M24 family protein 8.93 1 3 3 13 3.022E6 7.42 8.93 3 6 546.66 8.93 3 7 392 43.8 4.61 HVO_0402 DUF124 family protein 8.89 1 2 2 8 1.316E7 9.62 8.89 2 4 468.60 8.89 2 4 225 24.0 4.58 84040267 Keratin 6 isoform K6e [Homo sapiens] 8.87 1 0 5 28 1.248E8 29.59 8.87 5 14 1927.57 8.87 5 14 564 60.0 7.72 HVO_1055 TrkA domain protein 8.85 1 2 2 8 5.260E6 3.89 8.85 2 4 371.58 8.85 2 4 226 24.4 4.39 HVO_2932 GTP-binding protein 8.84 1 2 2 3 6.990E6 2.18 8.84 2 3 396 43.5 4.51 HVO_A0429_A homolog to mandelate racemase / homolog to muconate lactonizing enzyme 8.83 1 2 2 4 1.898E6 6.35 8.83 2 2 315.18 8.83 2 2 351 37.1 4.61 HVO_1005 ABC-type transport system permease protein 8.76 1 2 2 2 1.453E8 0.00 8.76 2 2 251 26.4 9.61 HVO_A0301 polysaccharide deacetylase family protein 8.70 1 2 2 2 1.853E6 161.75 8.70 2 2 299 34.2 4.56 HVO_1139 squalene synthase 8.66 1 2 2 4 5.214E6 4.07 8.66 2 2 220.35 8.66 2 2 358 39.7 4.54 HVO_2228 PHP domain protein 8.65 1 2 2 8 1.876E7 11.40 8.65 2 4 608.61 8.65 2 4 289 31.2 9.82 HVO_A0267 D-galactonate dehydratase 8.62 1 2 2 4 5.454E6 4.86 8.62 2 2 133.68 8.62 2 2 383 42.5 4.86 HVO_0733 transcription initiation factor TFB 8.59 1 0 3 6 2.524E7 5.34 8.59 3 3 361.63 8.59 3 3 326 37.2 6.00 HVO_A0570 probable metal-dependent hydrolase 8.58 1 2 3 7 4.123E6 2.16 7.51 2 3 212.56 8.58 3 4 466 50.4 4.56 HVO_0681 DNA topoisomerase I 8.57 1 6 6 20 1.228E7 17.83 8.57 6 10 932.99 8.57 6 10 840 93.6 4.58 HVO_2883 conserved hypothetical protein 8.55 1 4 4 17 5.666E6 20.40 8.55 4 8 1024.44 8.55 4 9 702 78.9 4.48 HVO_B0257 4-aminobutyrate aminotransferase 8.50 1 3 3 10 6.153E6 8.88 8.50 3 5 471.21 8.50 3 5 459 49.3 4.92 HVO_3001 ABC-type transport system permease protein 8.47 1 2 2 10 1.596E7 10.63 8.47 2 5 569.44 8.47 2 5 307 33.0 9.69 HVO_0103 conserved hypothetical protein 8.46 1 2 2 2 7.282E6 234.09 8.46 2 2 201 22.4 4.21 HVO_2509 sensor box histidine kinase 8.41 1 2 2 4 1.980E6 5.13 8.41 2 2 107.07 8.41 2 2 345 36.8 4.69 HVO_A0466 conserved hypothetical protein 8.36 1 2 2 2 6.513E6 2.77 8.36 2 2 550 58.2 4.53 HVO_1033 type IV pilus biogenesis complex membrane subunit 8.35 1 4 4 10 7.221E6 14.53 8.35 4 5 549.54 8.35 4 5 707 76.1 5.41 HVO_0120 signal recognition particle receptor FtsY 8.33 1 2 2 4 6.574E6 6.64 8.33 2 2 354.19 8.33 2 2 456 48.2 4.17 HVO_2156 UspA domain protein 8.31 1 2 2 4 6.168E6 5.96 8.31 2 2 262.70 8.31 2 2 301 31.6 4.69 HVO_1629 conserved hypothetical protein 8.29 1 3 3 10 6.587E6 2.16 5.65 2 4 346.08 8.29 3 6 531 56.3 4.69 HVO_0244 transport protein (probable substrate zinc/cadmium) 8.28 1 2 2 10 2.762E7 7.54 8.28 2 5 454.97 8.28 2 5 314 34.0 4.60 HVO_1609 conserved hypothetical protein 8.28 1 2 2 18 2.800E7 20.41 8.28 2 9 1517.11 8.28 2 9 290 31.0 4.58 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 8.25 1 0 4 21 6.542E7 9.45 8.25 4 10 940.86 8.25 4 11 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 8.25 1 0 4 21 6.542E7 9.45 8.25 4 10 940.86 8.25 4 11 400 44.1 5.14 HVO_2171 DUF58 family protein 8.21 1 3 3 14 1.436E7 9.95 8.21 3 7 611.47 8.21 3 7 475 50.8 4.93 HVO_2726 glutamate--tRNA ligase 8.21 1 4 4 17 1.043E7 8.50 8.21 4 8 723.19 8.21 4 9 585 65.2 4.58 HVO_0968 NADH dehydrogenase-like complex subunit CD 8.16 1 0 6 89 5.613E8 108.43 8.16 6 43 6122.63 8.16 6 46 564 63.3 4.60 HVO_A0085 conserved hypothetical protein 8.02 1 3 3 7 8.544E6 7.27 6.17 2 3 276.19 8.02 3 4 486 52.4 4.84 HVO_2580 L-aspartate oxidase 8.01 1 3 3 8 8.455E6 5.07 8.01 3 4 335.71 8.01 3 4 537 55.8 4.63 HVO_1880 conserved hypothetical protein 8.00 1 1 2 11 3.776E6 2.15 8.00 2 7 204.12 8.00 2 4 225 23.8 4.59 HVO_A0485 aminotransferase class V 7.98 1 2 2 8 9.475E6 10.47 7.98 2 4 512.08 7.98 2 4 351 37.3 4.26 HVO_1878 NAD synthase 7.97 1 2 2 12 8.645E5 9.08 7.97 2 6 648.70 7.97 2 6 276 29.6 4.37 HVO_3008 UPF0148 family protein 7.96 1 2 2 6 4.222E6 1.70 7.96 2 3 334.73 7.96 2 3 201 21.8 4.75 HVO_2360 peptidase S66 family protein 7.94 1 2 2 2 0.000E0 4.54 7.94 2 2 340 38.5 4.87 HVO_2298 UPF0135 family protein 7.91 1 2 2 6 3.980E6 7.29 7.91 2 3 376.29 7.91 2 3 253 26.5 4.37 HVO_A0329 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 7.91 1 2 2 4 4.420E6 3.68 7.91 2 2 138.20 7.91 2 2 215 22.0 4.58 HVO_0739 conserved hypothetical protein 7.90 1 2 2 15 1.608E7 16.75 7.90 2 8 921.48 7.90 2 7 329 33.5 4.97 HVO_1605 probable NhaC-type sodium/proton antiporter 7.88 1 3 3 10 3.120E7 9.21 7.88 3 5 496.52 7.88 3 5 520 54.9 4.86 HVO_2614 uridine phosphorylase 7.85 1 2 2 17 1.903E8 22.52 7.85 2 9 1031.41 7.85 2 8 242 25.8 4.30 HVO_A0629 sensor box histidine kinase 7.85 1 3 3 10 5.218E6 16.92 7.85 3 5 833.94 7.85 3 5 548 59.9 4.63 HVO_1262 probable NhaC-type sodium/proton antiporter 7.84 1 2 2 10 6.388E6 10.18 7.84 2 5 593.64 7.84 2 5 485 49.9 4.68 HVO_1008 GFO family oxidoreductase 7.83 1 2 2 6 1.338E7 7.59 7.83 2 3 333.06 7.83 2 3 332 36.0 4.72 HVO_0185 twin arginine translocation system subunit TatCt 7.80 1 4 4 15 1.328E7 20.90 7.80 4 7 970.91 7.80 4 8 718 77.9 4.94 HVO_A0425 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 7.80 1 2 2 4 8.234E6 4.80 7.80 2 2 257.32 7.80 2 2 346 38.4 5.24 HVO_A0045 HtpX-like protease 7.80 1 2 2 4 1.975E4 2.47 7.80 2 2 145.77 7.80 2 2 295 32.6 9.39 HVO_2227 siroheme decarboxylase AhbA 7.78 1 2 2 4 1.728E6 6.70 7.78 2 2 267.05 7.78 2 2 347 39.1 4.69 HVO_A0493 ABC-type transport system permease protein (probable substrate sugar) 7.77 1 2 2 8 7.142E6 10.93 7.77 2 4 500.56 7.77 2 4 309 34.1 8.65 HVO_1394 probable NhaC-type sodium/proton antiporter 7.75 1 4 4 11 3.038E7 9.24 5.62 3 5 722.11 7.75 4 6 516 53.0 4.84 HVO_2130 IclR family transcription regulator 7.72 1 2 2 8 7.900E6 10.85 7.72 2 4 467.08 7.72 2 4 272 30.1 5.55 HVO_2266 hypothetical protein 7.71 1 3 3 14 5.073E6 4.85 6.29 2 6 638.98 7.71 3 8 493 56.7 4.54 HVO_B0295 ABC-type transport system ATP-binding protein (probable substrate glycerol-3-phosphate) 7.69 1 2 2 15 2.835E7 18.64 7.69 2 8 1104.86 7.69 2 7 377 41.2 4.74 HVO_0162 peptidase M48 family protein 7.65 1 2 2 12 1.804E7 13.36 7.65 2 6 617.22 7.65 2 6 366 39.0 9.39 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 7.64 1 2 2 8 3.362E6 4.68 7.64 2 4 210.51 7.64 2 4 406 45.5 5.08 4504911 keratin 13 isoform b [Homo sapiens] 7.62 1 0 4 13 1.748E7 14.14 7.62 4 7 657.36 5.24 3 6 420 45.8 4.88 HVO_1741 conserved hypothetical protein 7.62 1 2 2 4 2.318E6 0.00 7.62 2 2 92.43 7.62 2 2 328 37.6 4.46 HVO_1066 Mrp-type sodium/proton antiporter system subunit D1 7.61 1 3 3 14 1.384E7 7.36 7.61 3 7 518.86 7.61 3 7 565 58.1 5.25 HVO_B0217 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 7.56 1 3 3 18 1.552E7 20.57 7.56 3 9 996.81 7.56 3 9 476 50.4 4.23 HVO_2164 ABC-type transport system permease protein (homolog to LolDCE lipoprotein release factor) 7.54 1 3 3 12 8.368E6 14.54 7.54 3 6 673.70 7.54 3 6 411 42.1 4.72 HVO_A0097 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 7.54 1 4 4 13 7.386E6 16.19 7.54 4 7 762.99 7.54 4 6 650 70.2 4.27 HVO_1128 sirohydrochlorin cobaltochelatase 7.53 1 2 2 3 7.548E5 225.23 7.53 2 3 292 32.3 4.42 HVO_1654 cysteine synthase 7.52 1 2 2 4 6.029E6 4.46 7.52 2 2 136.60 7.52 2 2 306 32.3 4.32 HVO_2161 conserved hypothetical protein 7.52 1 3 3 22 2.424E7 29.21 7.52 3 11 1403.72 7.52 3 11 359 36.7 3.88 HVO_0255 spermine/spermidine synthase family protein 7.45 1 3 3 8 7.890E6 7.76 7.45 3 4 360.66 7.45 3 4 537 58.0 4.96 HVO_B0100 aldehyde dehydrogenase 7.45 1 3 3 10 7.724E6 5.17 7.45 3 5 402.22 7.45 3 5 483 50.4 4.31 HVO_0022 ABC-type transport system periplasmic substrate-binding protein (probable substrate thiamine) 7.41 1 2 2 10 7.325E6 8.43 7.41 2 5 388.73 7.41 2 5 378 41.1 4.20 HVO_A0559 histidine ammonia-lyase 7.39 1 4 4 14 8.352E6 12.54 7.39 4 7 627.40 7.39 4 7 528 55.5 4.84 HVO_0984 NADH dehydrogenase-like complex subunit J2 7.38 1 2 2 5 8.657E4 0.00 7.38 2 2 225.54 7.38 2 3 122 12.8 4.54 HVO_B0149 oleate hydratase 7.32 1 2 3 5 1.204E7 2.13 3.38 2 2 155.03 7.32 3 3 533 60.1 4.64 HVO_1479 CHP03663 family protein 7.31 1 3 3 10 2.601E7 14.15 7.31 3 5 707.59 7.31 3 5 547 57.3 5.99 HVO_0987 NADH dehydrogenase-like complex subunit M 7.27 1 4 4 21 1.650E8 19.62 7.27 4 12 1154.23 7.27 4 9 509 54.7 5.08 HVO_2977 ArsA family ATPase 7.17 1 2 2 6 4.470E6 8.52 7.17 2 3 162.12 7.17 2 3 321 36.0 4.78 HVO_0702 DUF2298 family protein 7.12 1 4 4 14 1.270E7 14.02 7.12 4 7 880.51 7.12 4 7 787 82.8 6.04 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 6.99 1 0 4 13 1.748E7 14.14 6.99 4 7 657.36 4.80 3 6 458 49.6 4.96 HVO_0868 NAD-dependent epimerase/dehydratase 6.99 1 2 2 2 2.336E6 168.24 6.99 2 2 329 36.1 4.55 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 6.98 1 3 3 12 7.433E6 6.95 6.98 3 6 587.07 6.98 3 6 444 47.1 4.77 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 6.98 1 2 2 11 1.948E7 12.59 6.98 2 5 695.38 6.98 2 6 401 43.1 4.60 HVO_B0131 conserved hypothetical protein 6.97 1 2 2 6 1.591E6 5.13 6.97 2 3 309.27 6.97 2 3 287 32.2 4.84 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 7 5.546E7 1.84 6.94 3 4 201.08 3.34 2 3 389 40.8 4.89 HVO_A0270 glycerol-3-phosphate dehydrogenase subunit B 6.86 1 2 2 6 3.116E6 2.80 6.86 2 3 211.24 6.86 2 3 452 47.7 4.86 HVO_0102 HtpX-like protease 6.83 1 2 2 10 7.271E7 7.05 6.83 2 5 418.32 6.83 2 5 293 32.7 7.50 HVO_0853 DNA double-strand break repair protein Mre11 6.80 1 2 2 6 7.535E6 8.37 6.80 2 3 539.69 6.80 2 3 441 48.1 4.39 HVO_2955 DEAD/DEAH box helicase 6.80 1 3 3 5 2.167E6 1.82 6.80 3 3 139.60 3.85 2 2 779 85.8 4.94 HVO_2873 flap endonuclease Fen1 6.75 1 2 2 4 2.893E6 4.16 6.75 2 2 172.38 6.75 2 2 326 36.4 4.40 HVO_2311 glutamyl-tRNA reductase 6.72 1 2 2 3 2.397E6 4.27 6.72 2 3 461 49.2 4.54 HVO_C0077 sarcosine oxidase 6.72 1 2 2 6 2.458E6 7.29 6.72 2 3 282.24 6.72 2 3 387 42.9 4.70 HVO_1456 receiver/sensor box histidine kinase 6.72 1 1 2 2 2.447E6 164.48 6.72 2 2 506 53.8 4.70 HVO_1272 TrmB family transcription regulator 6.63 1 2 2 6 2.053E6 5.11 6.63 2 3 316.95 6.63 2 3 362 40.5 4.48 HVO_1338 replication protein A 6.56 1 3 3 12 5.439E6 13.20 6.56 3 6 664.94 6.56 3 6 427 46.0 4.36 HVO_2921 conserved hypothetical protein 6.54 1 2 2 2 1.565E7 0.00 6.54 2 2 306 32.7 4.34 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 6.53 1 2 2 2 3.992E6 249.33 6.53 2 2 337 35.9 4.69 HVO_1532 DUF368 family protein 6.52 1 2 2 8 2.645E7 9.69 6.52 2 4 432.75 6.52 2 4 322 32.8 6.54 HVO_0060 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 6.47 1 2 2 47 1.151E7 56.12 6.47 2 24 2319.31 6.47 2 23 479 51.5 5.11 HVO_2976 carbon starvation protein CstA 6.43 1 3 3 10 8.210E6 14.50 6.43 3 5 569.64 6.43 3 5 607 64.2 5.36 HVO_B0122 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) (nonfunctional) 6.43 1 2 2 5 4.897E7 96.36 6.43 2 5 544 60.4 4.32 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 6.39 1 2 2 6 5.650E7 7.72 6.39 2 3 314.64 6.39 2 3 360 39.5 4.31 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 6.38 1 2 2 16 1.935E8 10.61 6.38 2 8 798.20 6.38 2 8 345 37.0 3.95 HVO_2904 HtpX-like protease 6.31 1 2 2 4 1.492E6 4.01 6.31 2 2 101.14 6.31 2 2 317 34.7 7.65 HVO_0933 P-type transport ATPase (probable substrate copper/metal cation) 6.15 1 4 4 22 4.868E6 32.06 6.15 4 11 1592.34 6.15 4 11 943 99.2 4.55 HVO_1859 UPF0104 family protein 6.14 1 2 3 11 7.266E6 2.07 6.14 3 5 344.07 6.14 3 6 342 36.0 9.38 HVO_A0562 urocanate hydratase 6.13 1 2 2 4 2.752E6 2.71 6.13 2 2 138.80 6.13 2 2 620 67.9 4.70 28173552 keratin 6 irs4 [Homo sapiens] 6.05 1 1 3 19 5.788E7 21.89 3.59 2 9 1004.54 6.05 3 10 529 57.8 7.71 HVO_0321 peptide chain release factor aRF-1 6.04 1 2 2 8 4.640E6 8.25 6.04 2 4 297.13 6.04 2 4 414 46.6 4.83 HVO_0990 DHH family phosphoesterase 5.97 1 2 3 6 9.720E5 5.05 5.97 3 3 272.01 5.97 3 3 486 51.9 4.59 HVO_1625 conserved hypothetical protein 5.96 1 3 4 6 9.552E6 6.10 5.35 3 3 350.50 4.59 3 3 654 70.1 4.04 HVO_0798 dolichyl-phosphate mannosyltransferase AglD 5.93 1 3 3 18 1.311E7 21.48 5.93 3 9 793.58 5.93 3 9 624 66.9 5.19 HVO_1685 conserved hypothetical protein 5.89 1 3 3 12 8.852E6 8.80 5.89 3 6 568.17 5.89 3 6 492 54.5 5.74 HVO_2802 ABC-type transport system permease protein (probable substrate branched-chain amino acids) 5.84 1 2 2 8 2.987E6 9.25 5.84 2 4 313.40 5.84 2 4 445 47.4 8.51 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 5.78 1 3 3 16 1.154E7 8.60 5.78 3 8 603.24 5.78 3 8 658 72.1 4.70 HVO_0842 cytochrome bc1 complex cytochrome b subunit 5.68 1 2 2 9 1.616E7 0.00 5.68 2 4 336.92 5.68 2 5 264 30.5 6.89 HVO_2376 ABC-type transport system permease protein (probable substrate phosphate) 5.64 1 2 2 3 5.275E6 227.13 5.64 2 3 319 33.5 4.68 HVO_0970 ribulose-bisphosphate carboxylase large subunit 5.56 1 2 2 6 2.617E7 6.51 5.56 2 3 323.47 5.56 2 3 414 43.9 4.59 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 5.50 1 2 2 3 2.670E6 170.94 5.50 2 3 327 36.2 4.63 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 5.48 1 0 4 25 6.636E7 14.51 5.48 4 12 1267.61 5.48 4 13 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 5.48 1 0 4 25 6.636E7 14.51 5.48 4 12 1267.61 5.48 4 13 456 49.2 4.77 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 5.48 1 2 2 6 1.879E6 6.64 5.48 2 3 290.21 5.48 2 3 365 39.0 4.61 HVO_B0037 ABC-type transport system ATP-binding protein (probable substrate sugar) 5.48 1 0 2 14 3.487E7 23.22 5.48 2 7 1128.65 5.48 2 7 383 42.7 4.45 HVO_B0038 ABC-type transport system ATP-binding protein (probable substrate sugar) 5.48 1 0 2 14 3.487E7 23.22 5.48 2 7 1128.65 5.48 2 7 383 41.6 4.53 HVO_1356 sensor box histidine kinase 5.45 1 2 2 6 1.022E7 2.15 5.45 2 3 248.44 5.45 2 3 550 61.1 4.60 HVO_0945 ba3-type terminal oxidase subunit I 5.43 1 4 4 25 6.392E7 18.67 4.24 3 12 1335.66 5.43 4 13 589 64.3 6.71 HVO_B0321 GFO family oxidoreductase 5.43 1 2 2 8 9.940E6 9.69 5.43 2 4 478.80 5.43 2 4 368 41.0 4.48 HVO_A0064 Orc1-type DNA replication protein 5.41 1 1 2 2 2.575E6 108.76 5.41 2 2 499 55.5 4.91 HVO_1943 endoisopeptidase/DUF4129 domain protein 5.36 1 3 3 10 3.784E6 13.36 5.36 3 5 715.43 5.36 3 5 746 78.9 4.65 HVO_B0354 conserved hypothetical protein 5.35 1 4 4 12 1.066E7 15.84 5.35 4 6 773.34 5.35 4 6 767 85.4 4.68 HVO_2377 ABC-type transport system permease protein (probable substrate phosphate) 5.35 1 2 2 2 1.627E6 70.62 5.35 2 2 542 56.0 5.71 HVO_A0490 family 3 CoA transferase 5.30 1 2 2 4 1.377E6 2.09 5.30 2 2 72.93 5.30 2 2 415 44.4 4.50 HVO_2167 conserved hypothetical protein 5.28 1 2 2 4 6.840E6 2.21 5.28 2 2 188.95 5.28 2 2 303 31.8 5.12 31074633 keratin 6L [Homo sapiens] 5.23 1 0 3 16 1.054E8 16.29 5.23 3 8 1061.58 5.23 3 8 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 5.23 1 0 3 16 1.054E8 16.29 5.23 3 8 1061.58 5.23 3 8 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 5.23 1 0 3 16 1.054E8 16.29 5.23 3 8 1061.58 5.23 3 8 535 57.7 7.20 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 5.23 1 2 2 4 4.612E6 2.74 5.23 2 2 217.23 5.23 2 2 459 50.5 4.63 28173564 keratin 6 irs3 [Homo sapiens] 5.19 1 0 3 19 5.761E7 24.26 5.19 3 10 980.45 3.52 2 9 540 58.9 7.23 HVO_0648 DUF2070 family protein 5.18 1 2 2 10 5.869E6 2.34 5.18 2 5 294.96 5.18 2 5 637 67.7 4.77 HVO_2351 FxsA domain protein 5.15 1 2 2 6 1.942E7 4.43 5.15 2 3 200.18 5.15 2 3 194 20.1 5.29 HVO_1683 4-alpha-glucanotransferase 5.04 1 3 3 5 1.595E6 1.61 3.63 2 2 204.32 5.04 3 3 496 56.3 4.45 HVO_2717 alanine--tRNA ligase 5.03 1 2 2 2 2.376E6 136.44 5.03 2 2 398 41.6 4.39 31074631 keratin 1b [Homo sapiens] 5.02 1 0 3 18 1.622E8 19.28 5.02 3 9 1207.95 5.02 3 9 578 61.8 5.97 HVO_0662 HTH domain protein / thiamine-phosphate synthase 5.02 1 2 2 8 8.958E6 6.37 5.02 2 4 270.34 5.02 2 4 299 31.9 4.44 HVO_2693 ABC-type transport system permease protein (probable substrate sugar) 5.02 1 2 2 6 5.056E6 4.70 5.02 2 3 176.05 5.02 2 3 319 34.7 6.58 HVO_2581 quinolinate synthase A 4.94 1 2 2 8 4.786E6 6.86 4.94 2 4 535.61 4.94 2 4 385 42.0 4.41 HVO_2071 conserved hypothetical protein 4.92 1 2 2 6 6.504E6 2.81 4.92 2 3 292.38 4.92 2 3 549 58.4 4.72 HVO_A0439 DUF2800 family protein 4.91 1 1 2 2 4.572E5 0.00 4.91 2 2 326 36.9 4.51 HVO_2321 bacterial-type DNA primase DnaG 4.87 1 2 2 4 2.983E6 4.00 4.87 2 2 206.98 4.87 2 2 472 49.4 4.36 HVO_0756 phosphoesterase RecJ domain protein 4.82 1 2 2 6 2.513E6 1.76 4.82 2 3 180.51 4.82 2 3 394 41.5 4.78 HVO_1920 transport protein (probable substrate dicarboxylate) 4.79 1 2 2 12 5.204E7 11.92 4.79 2 6 573.95 4.79 2 6 522 55.0 4.74 HVO_0882 DUF373 family protein 4.76 1 2 2 8 4.686E6 4.50 4.76 2 4 421.90 4.76 2 4 378 40.2 4.55 HVO_1696 L-lactate permease 4.74 1 3 3 12 9.194E7 6.59 4.74 3 6 481.19 4.74 3 6 570 60.0 4.72 HVO_1725 Orc1-type DNA replication protein 4.74 1 1 2 2 2.000E6 126.40 4.74 2 2 401 44.5 5.19 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 4.72 1 5 5 12 3.549E6 7.86 4.72 5 6 415.39 4.72 5 6 1335 150.5 4.60 HVO_2482 HD family hydrolase 4.68 1 0 2 7 4.565E6 2.34 4.68 2 3 344.84 4.68 2 4 406 44.7 4.89 HVO_1940 DNA mismatch repair protein MutS 4.67 1 3 3 6 3.787E6 2.82 4.67 3 3 264.01 4.67 3 3 921 99.4 4.42 HVO_0506 ABC-type transport system ATP-binding/permease protein 4.65 1 3 3 6 4.272E6 4.59 4.65 3 3 265.59 4.65 3 3 645 71.7 4.59 HVO_2017 conserved hypothetical protein 4.58 1 2 2 6 2.819E6 1.76 4.58 2 3 185.49 4.58 2 3 459 48.2 4.98 HVO_A0180 SMC-like protein Sph1 4.55 1 2 3 4 8.256E4 0.00 3.71 2 2 133.26 1.85 2 2 593 66.4 4.58 HVO_A0271 glycerol-3-phosphate dehydrogenase subunit C 4.39 1 1 2 6 1.482E7 3.58 4.39 2 3 283.42 4.39 2 3 478 53.1 4.74 HVO_C0073 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 4.36 1 2 2 3 3.398E6 168.42 4.36 2 3 321 35.1 8.28 HVO_1442 ABC-type transport system permease protein 4.33 1 2 2 10 5.433E6 13.47 4.33 2 5 725.99 4.33 2 5 623 63.2 5.34 HVO_0621 sensor box histidine kinase 4.31 1 3 3 11 1.469E6 0.00 4.31 3 5 389.16 4.31 3 6 580 63.3 5.63 HVO_2079 RND superfamily permease 4.27 1 3 3 12 1.122E7 11.87 4.27 3 6 614.39 4.27 3 6 750 80.5 4.96 HVO_A0304 homolog to thermosome 4.24 1 3 3 7 7.742E5 3.88 2.88 2 3 215.55 4.24 3 4 590 61.9 4.78 HVO_1650 polyphosphate kinase 4.21 1 2 2 2 4.726E6 74.92 4.21 2 2 832 93.6 4.65 HVO_B0052 PQQ repeat protein 4.13 1 2 2 7 2.891E6 0.00 4.13 2 3 297.23 4.13 2 4 412 44.1 5.48 HVO_1057 Trk potassium uptake system protein TrkH 4.12 1 1 2 2 5.166E6 0.00 4.12 2 2 534 57.3 6.37 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 4.12 1 2 2 4 3.052E6 3.53 4.12 2 2 164.77 4.12 2 2 437 47.1 4.72 HVO_2256 DUF262 family protein 4.11 1 2 2 4 9.096E6 5.20 4.11 2 2 256.95 4.11 2 2 462 54.9 4.89 HVO_2249 xanthine/uracil permease family transport protein 3.90 1 2 2 15 4.556E6 1.66 3.90 2 8 583.17 3.90 2 7 462 46.8 4.34 HVO_2339 sensor box histidine kinase 3.80 1 2 2 6 5.435E6 6.69 3.80 2 3 349.89 3.80 2 3 606 64.6 4.74 HVO_0744 homolog to carboxylate-amine ligase 3.79 1 1 2 2 3.805E6 90.44 3.79 2 2 369 41.7 4.88 18031720 keratin protein K6irs [Homo sapiens] 3.73 1 0 2 18 8.392E7 21.89 3.73 2 9 980.45 3.73 2 9 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 3.72 1 0 2 18 8.392E7 21.89 3.72 2 9 980.45 3.72 2 9 511 55.8 6.89 109255249 keratin 4 [Homo sapiens] 3.70 1 0 3 13 6.695E7 7.92 3.70 3 6 800.98 3.70 3 7 594 63.9 8.25 HVO_1927 DUF389 family protein 3.69 1 2 2 4 2.789E6 2.57 3.69 2 2 107.31 3.69 2 2 434 45.6 4.60 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 18 8.392E7 21.89 3.63 2 9 980.45 3.63 2 9 523 57.3 6.61 HVO_2860 conserved hypothetical protein 3.56 1 2 2 2 1.826E7 2.24 3.56 2 2 562 58.9 4.49 4504919 keratin 8 [Homo sapiens] 3.52 1 0 2 12 7.540E7 7.01 3.52 2 6 673.38 3.52 2 6 483 53.7 5.59 HVO_0065 DNA-directed DNA polymerase D large subunit 3.49 1 3 3 10 4.244E6 12.56 3.49 3 5 654.67 3.49 3 5 1202 133.9 4.60 HVO_2766 ATP-dependent DNA helicase 3.49 1 2 2 7 4.484E6 7.29 3.49 2 4 141.78 3.49 2 3 918 102.7 5.07 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 14 8.865E7 5.15 3.45 2 7 600.32 3.45 2 7 464 50.6 5.47 HVO_1708 conserved hypothetical protein 3.33 1 2 2 4 8.737E6 0.00 3.33 2 2 90.28 3.33 2 2 781 82.6 5.22 HVO_A0154 SSSF family transport protein 3.28 1 2 2 4 1.545E7 3.50 3.28 2 2 158.77 3.28 2 2 549 58.2 4.75 HVO_0969 transducer protein Htr39 3.26 1 2 2 2 2.676E6 1.65 3.26 2 2 982 104.5 4.08 HVO_A0158 acyl-CoA synthetase 3.23 1 0 2 20 1.099E8 19.42 3.23 2 10 1290.39 3.23 2 10 650 71.2 4.63 HVO_2736 tRNA(Met) cytidine acetyltransferase 3.18 1 2 2 4 2.931E6 5.18 3.18 2 2 212.06 3.18 2 2 754 81.2 4.96 HVO_C0043 conserved hypothetical protein 3.18 1 2 2 2 6.156E6 131.95 3.18 2 2 661 73.8 4.75 HVO_1069 Mrp-type sodium/proton antiporter system subunit A 3.00 1 2 2 4 4.847E6 2.10 3.00 2 2 185.94 3.00 2 2 801 84.5 5.68 HVO_3000 DNA ligase (NAD) 3.00 1 2 2 12 7.825E7 9.47 3.00 2 6 537.80 3.00 2 6 699 75.8 4.50 66774007 "Keratin, type II cytoskeletal 1b" 2.95 1 0 2 6 6.218E7 1.94 2.95 2 3 268.59 2.95 2 3 576 61.7 5.85 HVO_0913 MATE efflux family protein 2.92 1 2 2 4 2.930E6 1.69 2.92 2 2 125.99 2.92 2 2 480 49.7 5.16 27894337 keratin 20 [Homo sapiens] 2.59 1 0 2 8 3.967E6 9.45 2.59 2 4 519.85 2.59 2 4 424 48.5 5.69 HVO_1656 YyaL family protein 2.13 1 2 2 3 3.372E6 185.10 2.13 2 3 703 77.3 4.49 HVO_B0265 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 1.15 1 0 2 2 6.012E7 110.11 1.15 2 2 1048 112.5 4.61