Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0356 translation elongation factor aEF-2 79.92 1 47 47 705 7.431E9 730.20 79.09 46 357 45782.24 78.95 46 348 727 80.4 4.73 HVO_0359 translation elongation factor aEF-1 alpha subunit 79.33 1 21 25 874 2.265E10 826.59 75.06 24 414 64153.89 79.33 25 460 421 45.7 4.73 HVO_1454 aspartate carbamoyltransferase catalytic subunit 76.32 1 15 15 73 1.975E8 75.31 75.99 14 37 4749.15 67.43 14 36 304 33.7 4.92 HVO_0880 conserved hypothetical protein 74.27 1 31 31 358 1.640E9 329.22 74.27 31 179 22378.91 74.27 29 179 307 36.3 4.74 HVO_2900 fumarate hydratase 72.71 1 22 22 148 1.714E9 159.54 70.79 21 74 9623.75 72.71 22 74 469 50.1 4.78 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 70.70 1 16 16 67 6.093E8 52.70 70.70 16 35 4035.08 63.66 14 32 355 38.2 4.68 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 70.29 1 17 17 252 4.053E9 256.99 70.29 17 128 16435.22 70.29 17 124 350 37.6 4.54 HVO_0329 branched-chain amino acid aminotransferase 69.55 1 16 16 95 8.820E8 103.58 56.09 14 46 6243.68 69.55 16 49 312 35.0 4.58 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 68.68 1 15 15 76 5.697E8 73.18 68.68 15 37 4740.11 68.68 15 39 281 30.6 4.59 HVO_2862 serine hydroxymethyltransferase 67.23 1 17 17 179 2.330E9 187.48 67.23 17 92 12587.09 67.23 17 87 415 44.3 4.53 HVO_0104 DNA repair and recombination protein RadA 66.47 1 16 16 107 1.115E9 82.34 61.22 15 51 7511.87 59.77 15 56 343 37.3 4.64 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 66.40 1 17 17 124 2.985E9 98.50 66.40 17 62 6946.07 66.40 17 62 381 41.0 4.23 HVO_1507 acetolactate synthase small subunit 65.60 1 10 10 46 1.771E8 33.17 65.60 10 23 3017.07 65.60 10 23 218 23.7 4.94 HVO_0055 CBS domain protein 65.14 1 13 13 67 9.845E8 72.11 65.14 13 33 5477.50 65.14 13 34 284 30.8 4.27 HVO_0581 "cell division protein FtsZ, type II" 64.75 1 17 17 117 9.242E8 128.40 59.75 16 59 8030.84 64.75 17 58 400 42.5 4.75 HVO_1921 serine--tRNA ligase 63.48 1 26 26 129 7.346E8 124.25 63.48 26 64 8201.56 63.48 26 65 460 52.0 4.46 HVO_2588 isocitrate dehydrogenase (NADP) 63.48 1 23 23 183 3.180E9 163.27 60.38 22 92 12388.82 56.09 22 91 419 45.8 4.59 HVO_0025 thiosulfate sulfurtransferase 63.29 1 13 13 258 5.395E9 244.09 60.84 12 130 15202.26 63.29 13 128 286 32.1 4.28 HVO_1273 inosine-5'-monophosphate dehydrogenase 63.25 1 21 21 232 1.201E9 217.77 60.64 20 115 14268.91 63.25 21 117 498 53.3 4.55 HVO_2783 30S ribosomal protein S4 62.86 1 12 12 58 8.998E8 47.52 62.86 12 29 3702.63 50.29 11 29 175 20.1 5.24 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 62.47 1 16 16 92 1.269E9 63.77 60.29 15 47 5244.41 62.47 16 45 413 45.8 4.45 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 60.93 1 15 15 73 4.518E8 83.26 60.93 15 37 5946.72 60.93 15 36 343 38.4 4.94 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 60.90 1 12 12 168 2.890E9 162.68 60.90 12 85 10343.33 60.90 12 83 312 34.5 4.98 HVO_0778 thermosome subunit 3 60.88 1 23 25 145 9.834E8 165.15 57.82 24 73 10711.01 60.88 24 72 524 55.2 4.59 HVO_0133 thermosome subunit 1 60.36 1 21 23 152 1.354E9 151.77 59.11 22 77 11342.24 53.93 21 75 560 58.9 4.25 HVO_0161 ATP phosphoribosyltransferase 60.14 1 13 13 64 3.591E8 60.87 60.14 13 33 4071.53 60.14 13 31 281 30.4 4.60 HVO_0859 FeS assembly ATPase SufC 60.13 1 18 18 153 1.778E9 118.18 58.14 17 76 9557.41 60.13 18 77 301 33.4 4.35 HVO_0347 DNA-directed RNA polymerase subunit B'' 60.08 1 29 29 190 9.105E8 128.78 60.08 28 92 11002.12 60.08 29 98 521 58.9 5.00 HVO_2519 conserved hypothetical protein 59.95 1 14 14 76 4.640E8 92.06 55.24 13 37 6080.84 59.95 14 39 382 40.7 4.35 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 59.90 1 17 17 143 1.915E9 165.94 59.90 17 71 11687.87 59.90 17 72 384 41.4 4.41 HVO_0348 DNA-directed RNA polymerase subunit B' 59.77 1 29 29 194 1.107E9 195.33 59.77 29 97 13115.27 59.77 29 97 609 67.7 4.92 HVO_1637 FKBP-type peptidylprolyl isomerase 59.48 1 11 12 92 2.694E9 90.61 50.98 11 43 6912.99 44.77 11 49 306 33.8 3.76 HVO_2779 50S ribosomal protein L18e 59.48 1 6 6 21 3.876E7 21.20 59.48 6 11 1077.99 59.48 6 10 116 12.7 8.50 HVO_0677 aspartate--tRNA ligase 59.45 1 18 18 234 2.523E9 237.88 59.45 18 119 15547.83 59.45 18 115 434 48.7 4.50 HVO_2889 RecJ domain protein 59.26 1 29 29 202 1.963E9 217.84 59.26 29 102 14868.38 59.26 29 100 729 79.1 4.37 HVO_0167 adenosylhomocysteinase 58.64 1 16 16 84 4.012E8 76.64 54.44 15 41 5191.06 58.64 16 43 428 46.6 4.39 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 58.04 1 10 10 38 3.468E8 33.44 51.40 9 18 2615.46 58.04 10 20 286 31.2 4.54 HVO_2191 formyltetrahydrofolate deformylase 57.19 1 15 15 74 8.527E8 65.39 57.19 15 37 5117.19 57.19 15 37 327 36.2 4.63 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 57.17 1 18 18 95 4.362E8 114.68 57.17 18 47 7026.35 57.17 18 48 474 53.4 4.59 HVO_0602 3-dehydroquinate dehydratase 57.09 1 11 11 36 1.231E8 27.35 57.09 11 18 1743.04 57.09 11 18 247 27.3 4.51 HVO_1133 conserved hypothetical protein 55.45 1 4 4 19 7.658E7 17.08 55.45 4 9 1304.93 55.45 4 10 101 11.7 4.58 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 55.45 1 14 14 69 2.770E8 78.85 55.45 14 34 4648.80 55.45 14 35 422 43.6 4.72 HVO_2413 translation elongation factor aEF-1 alpha subunit 55.24 1 13 17 143 3.217E9 103.24 55.24 17 70 8096.89 55.24 17 73 420 45.6 4.75 HVO_2968 phosphoglycerate dehydrogenase 55.24 1 19 19 171 1.770E9 198.40 55.24 19 86 13061.19 55.24 19 85 525 55.3 4.36 HVO_0317 A-type ATP synthase subunit B 55.13 1 15 17 133 2.382E9 160.72 55.13 17 66 10175.84 55.13 17 67 468 51.9 4.25 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 55.08 1 14 14 64 9.780E8 53.17 50.16 13 31 4200.04 48.85 12 33 305 33.8 4.74 HVO_1145 30S ribosomal protein S1e 55.00 1 10 10 56 6.787E8 53.47 55.00 10 28 3821.27 55.00 10 28 220 24.8 4.86 HVO_2724 beta-lactamase domain protein 54.44 1 19 19 197 1.886E9 180.31 53.11 18 98 11123.10 51.78 18 99 450 50.1 5.40 HVO_2336 pyridoxal biosynthesis lyase PdxS 54.30 1 12 12 42 2.072E8 38.47 43.71 9 19 2766.25 45.36 11 23 302 32.5 4.81 HVO_2621 phosphoenolpyruvate carboxylase 54.07 1 39 40 271 1.412E9 250.64 54.07 39 136 16783.19 54.07 40 135 897 102.3 4.64 HVO_0869 glutamate synthase large subunit 53.74 1 63 63 397 1.541E9 387.93 51.69 60 198 25954.35 53.74 63 199 1511 163.8 4.70 HVO_1284 GTP cyclohydrolase III 53.64 1 11 11 41 2.549E8 30.95 41.00 9 20 2215.35 53.64 11 21 261 28.9 4.70 HVO_2059 NAD-dependent epimerase/dehydratase 53.55 1 11 11 40 5.070E8 32.65 53.55 11 19 2670.31 53.55 11 21 310 34.1 4.40 HVO_2013 "FtsZ family protein, type III" 53.30 1 11 11 46 3.670E8 48.03 53.30 11 23 3414.21 53.30 11 23 394 41.5 4.61 HVO_0239 glutamine synthetase 53.29 1 19 19 134 2.452E9 135.99 53.29 18 67 9958.04 51.75 18 67 456 50.5 4.56 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 53.24 1 16 16 72 2.903E8 66.43 53.24 15 34 4957.70 53.24 16 38 340 38.8 4.58 HVO_0870 proline--tRNA ligase 52.87 1 17 17 108 6.874E8 86.09 50.41 16 54 6691.31 52.87 17 54 488 54.9 4.44 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 52.19 1 11 11 65 6.673E8 36.38 45.79 9 32 3270.41 52.19 11 33 297 31.3 4.36 HVO_1502 3-isopropylmalate dehydrogenase 51.85 1 13 13 67 9.504E8 59.74 44.14 12 33 4893.33 51.85 13 34 324 33.7 4.23 HVO_2552 30S ribosomal protein S4e 51.82 1 9 9 142 4.595E9 131.96 51.82 9 73 7665.11 51.82 9 69 247 26.6 4.58 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 51.60 1 23 23 106 3.303E8 89.61 49.68 22 51 6731.93 51.60 23 55 626 67.6 4.65 HVO_2756 50S ribosomal protein L10 51.15 1 12 12 74 6.801E8 49.59 49.43 11 36 4833.20 51.15 12 38 348 36.9 3.99 HVO_1973 conserved hypothetical protein 50.90 1 5 5 26 1.664E8 32.68 41.92 4 12 2464.79 50.90 5 14 167 18.1 4.36 HVO_2435 peptidase M24 family protein 50.82 1 11 11 44 1.791E8 40.80 50.82 11 23 2846.48 50.82 11 21 368 40.0 4.53 HVO_1649 methionine adenosyltransferase 50.75 1 14 14 55 2.514E8 53.52 50.75 14 28 3214.20 50.75 14 27 402 43.5 4.45 HVO_1189 aldehyde dehydrogenase 50.59 1 18 18 83 4.849E8 71.65 43.31 17 41 5357.76 50.59 18 42 508 56.1 4.59 HVO_0046 putative glutamate--argW ligase 50.52 1 11 11 65 4.936E8 60.14 50.52 11 31 4728.54 50.52 11 34 291 31.9 4.87 HVO_0480 phosphoglycerate kinase 50.37 1 16 16 89 8.267E8 114.76 50.37 16 46 7597.05 44.14 15 43 401 43.6 4.37 HVO_1541 glycerol kinase 50.20 1 21 21 139 2.118E9 109.36 46.86 20 68 8818.52 50.20 21 71 510 56.7 4.50 HVO_2015 conserved hypothetical protein 50.14 1 12 12 136 5.249E9 139.14 50.14 12 68 9646.07 50.14 12 68 345 37.7 4.25 HVO_0212 homolog to lactoylglutathione lyase 50.00 1 4 4 11 1.867E8 10.97 50.00 4 6 814.56 50.00 4 5 124 13.5 4.13 HVO_0850 proteasome-activating nucleotidase 49.88 1 14 14 97 5.373E8 109.92 44.69 13 49 6811.09 49.88 14 48 405 45.6 4.60 HVO_1338 replication protein A 49.65 1 15 15 51 2.492E8 37.24 48.01 14 26 3052.05 43.09 14 25 427 46.0 4.36 HVO_0860 SufB domain protein 49.58 1 21 21 168 1.563E9 141.62 47.90 20 83 9872.39 49.58 21 85 476 53.2 4.69 HVO_0861 SufB domain protein 49.50 1 14 14 97 1.459E9 94.74 49.50 14 48 7233.52 49.50 14 49 402 44.7 4.23 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 49.48 1 11 11 102 1.315E9 115.88 49.48 11 53 7329.18 47.74 10 49 287 31.0 4.73 HVO_1684 threonine--tRNA ligase 49.46 1 29 29 155 9.906E8 134.24 49.46 29 77 9703.04 49.46 29 78 643 73.4 4.45 HVO_2204 "FtsZ family protein, type III" 49.37 1 13 16 83 1.121E9 90.19 49.37 16 42 6157.81 47.59 15 41 395 42.0 4.68 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 48.99 1 20 20 149 1.498E9 149.92 47.47 19 74 9686.76 48.99 20 75 592 66.6 4.61 HVO_0999 DRTGG domain protein 48.94 1 13 13 72 4.776E8 85.22 48.94 13 36 5409.88 48.94 13 36 378 39.8 4.44 HVO_0292 replication protein A 48.87 1 11 11 47 2.009E8 50.39 48.87 11 24 3446.54 48.87 11 23 311 34.6 4.31 HVO_0206 alanine--tRNA ligase 48.81 1 33 33 173 3.827E8 155.82 47.07 30 86 11262.19 48.81 33 87 922 102.4 4.54 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 48.79 1 9 9 80 1.421E9 80.43 45.67 8 39 6451.81 42.21 8 41 289 29.8 4.27 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 48.76 1 13 13 59 2.987E8 71.05 48.76 13 29 3685.24 48.76 13 30 445 47.8 4.86 HVO_2969 threonine synthase 48.21 1 16 16 84 1.168E9 87.64 46.54 15 42 6582.22 48.21 16 42 419 44.4 4.49 HVO_2384 CBS domain protein 48.16 1 15 15 157 1.556E9 139.30 48.16 15 79 8927.06 48.16 15 78 380 42.5 5.01 HVO_0694 probable phosphoribosyltransferase 48.10 1 10 10 37 2.929E7 34.38 44.30 9 18 2527.66 48.10 10 19 237 27.0 4.32 HVO_2419 hydroxymethylglutaryl-CoA synthase 48.09 1 18 18 76 6.377E8 60.36 48.09 18 37 4263.99 48.09 18 39 445 50.1 4.64 HVO_1132 adenylosuccinate synthase 48.08 1 21 21 153 2.178E9 137.18 44.92 20 75 9879.65 48.08 21 78 443 48.2 4.56 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 47.89 1 6 6 40 5.792E8 36.55 47.89 6 19 2988.82 47.89 6 21 190 20.6 4.30 HVO_0353 30S ribosomal protein S12 47.89 1 10 10 45 5.908E8 46.69 47.89 10 22 2980.89 44.37 9 23 142 15.5 9.91 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 47.78 1 13 13 71 5.782E8 51.08 39.72 12 35 3994.06 47.78 13 36 360 39.6 4.39 HVO_0792 3-dehydroquinate synthase type II 47.70 1 14 14 73 4.934E8 82.11 47.70 14 37 5262.54 46.17 12 36 392 43.1 4.44 HVO_3007 malate dehydrogenase 47.70 1 15 15 158 2.980E9 140.33 47.70 15 80 8289.77 45.72 14 78 304 32.6 4.40 HVO_2544 30S ribosomal protein S5 47.66 1 9 9 55 1.804E9 49.38 47.66 9 29 3185.14 45.33 8 26 214 23.3 9.29 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 47.62 1 15 15 55 3.168E8 39.75 43.15 14 27 3107.69 47.62 15 28 336 38.0 4.61 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 47.52 1 8 8 36 8.894E7 20.11 47.52 8 18 1991.86 47.52 8 18 202 22.2 5.11 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 47.48 1 12 12 68 3.968E8 84.16 47.48 12 33 5195.27 47.48 12 35 457 48.4 4.35 HVO_0203 replication factor C small subunit 47.40 1 13 13 58 3.130E8 54.11 47.40 13 29 3788.13 47.40 13 29 327 36.2 4.51 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 47.02 1 14 14 68 4.013E8 63.22 47.02 14 35 4163.46 47.02 14 33 453 47.5 4.63 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 46.91 1 21 21 310 5.064E9 324.51 45.64 20 155 22173.37 46.91 21 155 631 68.4 4.49 HVO_0393 UvrABC system protein A 46.90 1 34 34 134 2.367E8 129.80 45.37 32 67 8334.54 46.90 34 67 983 108.6 4.82 HVO_2624 CTP synthase 46.45 1 17 17 102 6.796E8 75.46 44.44 16 50 6575.99 44.81 16 52 549 60.8 4.70 HVO_A0406 conserved hypothetical protein 46.42 1 2 12 46 3.238E8 42.49 46.42 12 23 2652.91 46.42 12 23 405 44.4 5.30 HVO_A0206 CRISPR-associated protein Cas8b 46.30 1 24 24 99 4.209E8 87.04 46.30 24 50 5957.98 43.51 23 49 717 79.3 4.60 HVO_1031 thioredoxin-disulfide reductase 46.20 1 11 11 47 2.829E8 41.47 41.52 10 22 2976.87 46.20 11 25 342 37.4 4.46 HVO_0980 NADH dehydrogenase-like complex subunit CD 46.14 1 15 20 104 5.455E8 77.34 46.14 20 53 6060.79 46.14 20 51 557 63.4 4.53 HVO_0809 methionine--tRNA ligase 45.95 1 24 24 113 5.439E8 114.42 45.95 24 56 7733.04 45.00 23 57 740 81.9 4.37 HVO_0424 ABC-type transport system ATP-binding protein 45.70 1 20 20 88 2.867E8 84.74 43.71 19 44 4985.05 45.70 20 44 604 67.2 4.49 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 45.67 1 20 20 107 5.355E8 107.01 44.71 19 53 6896.22 45.67 20 54 624 67.6 4.27 HVO_2188 phosphoribosylformylglycinamidine synthase 1 45.54 1 8 8 37 3.875E8 34.99 45.54 8 18 2654.32 45.54 8 19 224 23.9 4.36 HVO_2558 30S ribosomal protein S3 45.39 1 11 11 117 2.747E9 112.76 41.12 10 57 9163.71 45.39 11 60 304 33.4 4.06 HVO_2961 dihydrolipoyl dehydrogenase 45.26 1 13 13 63 2.261E8 56.06 33.05 10 29 3901.93 45.26 13 34 475 49.9 4.41 HVO_2981 uracil phosphoribosyltransferase 45.13 1 9 9 41 6.412E8 40.04 37.61 8 18 3501.96 45.13 9 23 226 24.5 4.49 HVO_B0118 SMC-like protein Sph2 45.03 1 28 29 113 8.266E8 106.59 43.79 28 59 6699.50 43.48 27 54 644 73.8 4.41 HVO_A0207 CRISPR-associated protein Cas7 45.00 1 9 9 55 7.204E8 57.19 45.00 9 29 3583.08 45.00 9 26 340 38.2 4.54 HVO_2487 aspartate-semialdehyde dehydrogenase 44.77 1 8 8 64 1.117E9 68.85 44.77 8 31 4103.27 44.77 8 33 344 36.6 4.41 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 44.76 1 21 21 105 5.670E8 81.37 44.76 21 52 6504.35 44.76 21 53 496 55.0 4.53 HVO_1690 DHH family phosphoesterase 44.74 1 12 12 41 1.567E8 36.50 44.74 12 21 2606.29 44.74 12 20 485 52.1 4.48 HVO_1123 thioredoxin-disulfide reductase 44.70 1 10 10 43 5.259E8 34.78 41.55 9 20 2648.29 44.70 10 23 349 37.3 4.32 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 44.63 1 11 11 50 1.746E8 36.97 40.77 10 24 2727.65 44.63 11 26 363 39.3 4.97 HVO_A0205 CRISPR-associated endoribonuclease Cas6 44.49 1 11 11 56 3.277E8 55.36 44.49 11 28 3859.01 44.49 11 28 272 31.0 5.44 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 44.41 1 18 18 64 2.506E8 71.52 44.41 18 32 5198.57 44.41 18 32 599 65.3 4.51 HVO_0449 prephenate dehydratase 44.40 1 9 9 38 4.385E8 40.88 44.40 9 19 2679.16 44.40 9 19 268 28.7 4.64 HVO_0455 thermosome subunit 2 44.34 1 22 23 139 1.132E9 124.64 44.34 23 70 9574.61 43.27 22 69 557 59.3 4.37 HVO_1080 conserved hypothetical protein 44.15 1 6 6 25 2.061E8 24.49 39.89 5 12 1623.81 44.15 6 13 188 21.1 4.31 HVO_0806 pyruvate kinase 44.10 1 18 18 118 8.926E8 115.91 44.10 18 59 8051.94 42.91 17 59 585 62.0 4.54 HVO_2549 30S ribosomal protein S8 43.85 1 5 5 26 4.401E8 23.80 43.85 5 13 1658.17 43.85 5 13 130 14.1 4.79 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 43.83 1 22 22 96 2.703E8 70.92 37.83 20 45 6364.35 43.83 22 51 600 65.3 4.68 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 43.76 1 39 39 235 7.524E8 210.16 42.30 37 115 14741.43 41.63 38 120 1033 114.3 4.45 HVO_2646 dihydroxy-acid dehydratase 43.66 1 17 17 117 9.512E8 125.76 43.66 17 59 8284.68 43.66 17 58 584 61.8 4.42 HVO_0109 cysteine desulfurase 43.66 1 15 15 65 2.693E8 55.03 43.66 15 32 4179.57 43.66 15 33 426 46.8 4.56 HVO_0989 conserved hypothetical protein 43.65 1 5 5 13 5.236E7 0.00 41.27 4 6 428.31 43.65 5 7 126 14.4 4.81 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 43.63 1 9 9 44 5.397E8 50.51 43.63 9 21 3545.08 43.63 9 23 259 28.0 4.50 HVO_1084 adenylosuccinate lyase 43.63 1 17 17 66 4.312E8 67.27 37.15 15 32 4715.11 43.63 17 34 463 50.8 4.70 HVO_2774 enolase 43.61 1 11 11 58 1.130E9 54.84 43.61 11 28 3827.10 41.85 10 30 399 42.0 4.37 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 43.43 1 16 16 95 9.624E8 103.72 40.38 14 47 7172.24 42.48 15 48 525 56.4 4.40 HVO_0388 homolog to ribonuclease R 43.28 1 16 16 77 3.662E8 83.65 43.28 16 40 5097.93 40.55 15 37 439 50.3 4.73 HVO_1091 proteasome alpha subunit 43.25 1 10 11 51 9.212E8 54.39 40.87 10 25 3588.48 43.25 11 26 252 27.6 4.56 HVO_1590 DnaK-type molecular chaperone Hsp70 43.04 1 24 24 175 1.649E9 153.46 43.04 24 88 10515.49 43.04 24 87 625 67.2 4.18 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 43.00 1 19 19 165 1.572E9 149.46 43.00 19 86 10665.35 43.00 19 79 586 64.0 4.49 HVO_1504 3-isopropylmalate dehydratase large subunit 42.92 1 16 17 120 1.559E9 137.73 42.92 17 61 9170.48 42.92 17 59 473 51.6 4.55 HVO_0415 repair helicase 42.86 1 20 20 100 4.271E8 87.08 42.86 20 51 6328.06 41.88 19 49 616 69.6 4.70 HVO_1082 homolog to orotate phosphoribosyltransferase 42.86 1 8 8 25 2.688E8 16.55 42.86 8 14 1293.90 35.71 6 11 210 22.3 4.42 HVO_2813 RimK family protein 42.83 1 15 15 94 6.953E8 85.20 42.83 15 47 6162.04 42.83 15 47 453 49.0 4.73 HVO_1545 dihydroxyacetone kinase subunit DhaL 42.67 1 8 8 39 4.719E8 32.89 39.66 7 18 2414.03 42.67 8 21 232 24.8 4.48 HVO_0314 A-type ATP synthase subunit C 42.53 1 15 15 60 4.686E8 44.80 36.49 13 29 3847.25 42.53 15 31 348 38.7 4.50 HVO_2156 UspA domain protein 42.52 1 9 9 34 4.427E8 36.28 42.52 9 17 2592.20 42.52 9 17 301 31.6 4.69 HVO_2425 GNAT family acetyltransferase 42.13 1 7 7 26 8.594E7 14.88 42.13 7 13 1458.03 42.13 7 13 216 24.4 4.54 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.11 1 9 9 58 4.353E8 63.61 42.11 9 29 4303.76 42.11 9 29 266 27.8 4.84 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 41.99 1 7 7 32 1.610E8 28.63 41.99 7 16 2368.13 41.99 7 16 231 25.0 4.25 HVO_0196 conserved hypothetical protein 41.82 1 2 2 6 1.244E8 5.01 41.82 2 3 435.10 41.82 2 3 55 6.2 4.81 HVO_0829 peptidase S9 family protein 41.78 1 14 14 48 1.665E8 41.13 41.78 14 25 2525.80 37.83 13 23 608 67.4 4.54 HVO_2057 sugar nucleotidyltransferase 41.74 1 12 12 68 7.569E8 70.56 41.74 12 34 5071.52 41.74 12 34 357 37.8 4.44 HVO_0316 A-type ATP synthase subunit A 41.64 1 19 19 158 1.859E9 200.19 41.64 19 77 13394.15 41.64 19 81 586 64.5 4.25 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 41.63 1 13 13 51 1.881E8 46.69 41.63 13 26 2873.35 38.55 12 25 454 48.5 4.46 HVO_2373 30S ribosomal protein S8e 41.60 1 3 3 12 4.474E7 6.91 41.60 3 6 491.22 41.60 3 6 125 13.6 10.48 HVO_0087 porphobilinogen synthase 41.59 1 9 9 28 1.382E8 15.11 41.59 9 14 1314.38 41.59 9 14 327 35.3 4.72 HVO_0789 tryptophan synthase alpha subunit 41.52 1 7 7 33 2.561E8 33.05 41.52 7 17 2111.06 41.52 7 16 277 29.6 4.21 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 41.51 1 8 8 26 8.544E7 29.24 41.51 8 14 1874.32 32.83 7 12 265 29.3 4.92 HVO_1824 conserved hypothetical protein 41.49 1 12 12 45 2.201E8 56.83 41.49 12 22 3847.87 41.49 12 23 429 47.4 4.20 HVO_0433 F420H2:NADP oxidoreductase 41.44 1 5 5 24 4.232E8 28.05 41.44 5 12 2044.80 41.44 5 12 222 23.3 4.72 HVO_0358 homoserine dehydrogenase 41.32 1 7 8 39 4.010E8 43.64 41.32 8 20 2655.17 39.43 7 19 317 32.4 4.44 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 41.31 1 11 11 85 8.158E8 50.22 37.45 10 39 4952.60 41.31 11 46 259 29.9 4.36 HVO_0313 A-type ATP synthase subunit E 41.24 1 6 6 37 3.170E8 38.22 31.44 4 15 2499.13 41.24 6 22 194 22.0 4.31 HVO_2700 AAA-type ATPase (CDC48 subfamily) 41.11 1 28 29 109 2.175E8 91.03 41.11 29 56 5835.91 38.20 27 53 754 82.8 4.75 HVO_0743 probable phosphodiesterase 40.98 1 21 21 119 6.768E8 98.21 39.64 20 58 7661.52 40.98 21 61 449 50.5 4.56 HVO_0417 metal-dependent carboxypeptidase 40.84 1 14 14 62 2.965E8 52.15 37.45 13 30 4112.16 40.84 14 32 502 57.3 4.42 HVO_0024 thiosulfate sulfurtransferase 40.70 1 8 8 38 4.121E8 31.97 36.05 7 19 2905.76 40.70 8 19 258 28.4 4.30 HVO_1572 DNA gyrase subunit B 40.69 1 20 20 87 2.980E8 72.46 40.69 20 44 5051.02 40.69 20 43 639 71.2 4.83 HVO_1300 triosephosphate isomerase 40.65 1 5 5 42 9.032E8 36.17 40.65 5 22 2506.76 40.65 5 20 214 21.3 4.26 HVO_0100 NMD3 family protein 40.53 1 10 10 30 9.568E7 30.03 40.53 10 15 1924.56 40.53 10 15 375 41.6 4.46 HVO_1955 aconitate hydratase 40.52 1 21 21 198 3.046E9 204.33 40.52 21 100 14261.36 40.52 21 98 654 70.4 4.45 HVO_0661 dCTP deaminase (dUMP-forming) 40.51 1 5 5 24 1.079E8 11.99 40.51 5 12 1015.84 40.51 5 12 195 21.2 4.59 HVO_0349 DNA-directed RNA polymerase subunit A' 40.47 1 30 30 195 7.513E8 203.00 40.47 30 96 13435.28 40.47 30 99 976 108.8 4.81 HVO_2548 50S ribosomal protein L6 40.45 1 5 5 16 7.227E7 19.56 40.45 5 8 1257.61 40.45 5 8 178 19.6 4.68 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 40.34 1 15 15 64 3.285E8 63.25 36.94 14 31 4079.54 40.34 15 33 471 51.0 4.48 HVO_1306 chorismate synthase 40.26 1 11 11 60 2.303E8 69.29 40.26 11 30 3751.33 40.26 11 30 385 41.9 4.83 HVO_0243 threonine aldolase 40.18 1 9 9 47 9.665E7 52.51 40.18 9 23 3451.66 40.18 9 24 341 35.6 4.55 HVO_2454 anthranilate synthase component I 40.08 1 16 16 59 3.143E8 67.37 40.08 16 30 4832.22 40.08 16 29 524 55.9 4.56 HVO_A0432 conserved hypothetical protein 40.00 1 1 11 35 2.312E8 32.33 40.00 11 18 2213.64 34.32 10 17 405 44.5 5.24 HVO_0138 tyrosine--tRNA ligase 39.94 1 9 9 41 4.271E8 31.49 39.94 9 20 2335.84 39.94 9 21 328 36.1 4.34 HVO_2333 conserved hypothetical protein 39.94 1 10 10 29 8.677E7 14.32 37.66 9 15 1031.06 39.94 10 14 308 34.9 4.54 HVO_1212 KaiC-type circadian regulator CirA 39.84 1 9 9 43 7.973E8 50.98 37.80 8 21 3554.47 39.84 9 22 246 27.5 4.45 HVO_0511 NAD-dependent epimerase/dehydratase 39.69 1 7 7 24 9.026E7 18.97 39.69 7 12 1444.32 30.53 6 12 262 29.3 4.78 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 39.54 1 12 12 57 4.425E8 52.53 33.84 11 27 3393.86 39.54 12 30 526 57.2 4.31 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 39.50 1 10 10 35 2.896E8 22.77 36.46 9 17 2025.99 39.50 10 18 362 39.6 4.82 HVO_0041 ornithine carbamoyltransferase 39.46 1 8 8 48 2.368E8 47.36 39.46 8 24 2898.26 39.46 8 24 299 32.7 4.37 HVO_1854 histidine--tRNA ligase 39.44 1 14 14 76 3.988E8 67.76 39.44 14 38 5254.61 39.44 14 38 431 47.1 4.37 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 39.37 1 6 6 20 2.086E8 24.83 39.37 6 10 1336.38 39.37 6 10 254 26.9 4.42 HVO_1481 UspA domain protein 39.26 1 5 5 26 4.262E8 21.41 39.26 5 12 1369.33 39.26 5 14 163 17.7 4.40 HVO_1901 translation initiation factor aIF-2 gamma subunit 39.17 1 13 13 77 9.400E8 54.74 39.17 13 37 4131.97 39.17 13 40 411 43.9 4.36 HVO_2690 GFO family oxidoreductase 39.07 1 11 11 51 4.960E8 35.81 39.07 11 26 2931.64 39.07 11 25 366 40.0 4.60 HVO_0874 beta-lactamase domain protein 39.06 1 21 21 103 7.769E8 90.41 39.06 21 52 7180.42 39.06 21 51 640 71.9 5.14 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 38.93 1 10 10 48 9.275E8 50.18 38.93 10 23 3578.73 38.93 10 25 280 30.1 4.44 HVO_A0458 ParA domain protein 38.83 1 7 7 22 8.472E7 21.11 38.83 7 12 1103.86 36.08 6 10 291 32.2 4.79 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 38.79 1 8 8 38 1.956E8 38.04 38.79 8 19 2260.45 38.79 8 19 330 36.3 4.35 HVO_1465 naphthoate synthase 38.69 1 7 7 32 1.650E8 25.57 30.16 6 15 1930.02 38.69 7 17 305 33.9 4.83 HVO_0467 PhoU/TrkA-C domain protein 38.56 1 13 13 44 8.771E7 36.38 36.57 12 21 2673.80 38.56 13 23 402 43.3 4.49 HVO_2040 NAD-dependent epimerase/dehydratase 38.56 1 5 9 56 6.309E8 56.04 38.56 9 28 3667.94 38.56 9 28 306 33.8 4.51 HVO_0911 GTP-binding protein Drg 38.48 1 11 11 33 6.025E7 20.09 38.48 11 17 1598.22 36.59 10 16 369 40.5 4.81 47132620 keratin 2a [Homo sapiens] 38.34 1 16 23 109 6.784E8 108.52 38.34 23 54 7265.92 38.34 23 55 639 65.4 8.00 HVO_0519 replication protein A 38.30 1 15 15 71 3.272E8 65.97 38.30 15 34 5040.68 38.30 15 37 483 51.0 4.13 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 38.22 1 12 12 73 4.567E8 76.57 38.22 12 38 4676.15 38.22 12 35 348 38.2 4.32 HVO_0541 aconitate hydratase 38.17 1 23 23 81 3.965E8 45.85 37.10 22 40 4275.87 34.75 22 41 938 102.1 4.40 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 77 5.624E8 87.12 35.50 8 36 5824.64 38.05 9 41 431 46.1 4.48 HVO_2029 Lrp/AsnC family transcription regulator 37.91 1 3 4 20 2.394E8 5.31 37.91 4 10 661.64 37.91 4 10 153 16.9 4.21 HVO_1370 gamma-glutamyl phosphate reductase 37.84 1 14 14 55 3.243E8 44.83 37.84 14 28 3565.06 37.84 14 27 444 48.1 4.34 HVO_1164 HD family hydrolase 37.78 1 9 9 31 1.882E8 20.60 33.70 8 15 2081.07 37.78 9 16 270 29.8 4.87 HVO_2883 conserved hypothetical protein 37.75 1 18 18 70 1.224E8 73.31 37.75 18 35 4839.61 37.75 18 35 702 78.9 4.48 HVO_2726 glutamate--tRNA ligase 37.61 1 17 17 83 3.678E8 57.69 37.61 17 42 4808.23 37.61 17 41 585 65.2 4.58 HVO_1550 acyl-CoA thioester hydrolase 37.50 1 4 4 15 1.224E8 12.37 30.63 3 6 1179.70 37.50 4 9 160 17.6 4.55 HVO_1562 proteasome beta subunit 37.45 1 7 7 40 3.728E8 33.39 37.45 7 20 2346.74 37.45 7 20 243 26.0 4.63 HVO_A0021 conserved hypothetical protein 37.40 1 5 5 12 4.378E7 1.72 24.43 3 4 622.24 37.40 5 8 131 14.9 4.42 HVO_0049 argininosuccinate synthase 37.28 1 14 14 67 1.130E9 39.06 37.28 14 34 3676.63 37.28 14 33 405 44.5 4.34 HVO_0354 30S ribosomal protein S7 37.25 1 7 7 23 2.947E8 21.04 28.43 6 11 1744.94 37.25 7 12 204 22.6 5.14 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.05 1 11 11 88 6.541E8 52.33 37.05 11 45 4001.55 37.05 11 43 332 34.8 4.22 HVO_0321 peptide chain release factor aRF-1 36.96 1 13 13 47 2.419E8 26.35 36.96 13 24 2159.47 35.02 12 23 414 46.6 4.83 HVO_1076 sugar nucleotidyltransferase 36.96 1 8 8 39 4.594E8 44.78 36.96 8 20 2815.63 35.09 7 19 322 35.8 4.20 HVO_0240 Lrp/AsnC family transcription regulator 36.84 1 4 5 17 3.973E8 13.33 31.58 4 7 1180.34 36.84 5 10 152 16.9 4.39 HVO_1018 RecJ domain protein 36.81 1 21 21 108 6.460E8 95.24 35.39 20 54 7365.87 36.81 21 54 633 69.8 4.58 HVO_1198 UspA domain protein 36.55 1 5 5 17 3.771E8 12.98 36.55 5 9 968.63 36.55 5 8 145 15.6 4.75 HVO_2773 30S ribosomal protein S2 36.54 1 7 7 60 2.583E9 80.95 36.15 6 29 4606.77 36.54 7 31 260 28.3 4.16 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 36.52 1 13 13 53 2.284E8 57.34 36.52 13 26 3889.62 36.52 13 27 512 53.8 4.78 HVO_0402 DUF124 family protein 36.44 1 5 5 10 7.128E7 6.15 36.44 5 5 451.27 25.33 4 5 225 24.0 4.58 HVO_0788 tryptophan synthase beta subunit 36.26 1 12 12 47 2.564E8 49.68 32.46 10 24 2560.14 36.26 12 23 422 45.7 4.65 HVO_B0059 cobalt-precorrin 5A hydrolase 36.20 1 8 8 37 7.962E7 34.36 36.20 8 19 2135.91 36.20 8 18 326 34.5 4.51 HVO_2721 amidophosphoribosyltransferase 36.11 1 11 11 44 7.124E8 39.66 36.11 11 22 2961.59 36.11 11 22 493 53.4 4.78 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 36.08 1 4 4 26 5.865E8 26.17 25.26 3 12 2199.58 36.08 4 14 194 20.7 4.12 17318569 keratin 1 [Homo sapiens] 36.02 1 1 26 160 8.918E8 156.16 36.02 26 80 10930.46 36.02 26 80 644 66.0 8.12 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 35.98 1 4 4 27 1.590E8 9.47 35.98 4 14 1263.76 35.98 4 13 189 21.7 4.46 HVO_0008 aspartate kinase 35.97 1 9 9 49 8.526E8 44.85 35.97 9 25 2737.95 35.97 9 24 392 41.7 4.46 HVO_0324 arginine--tRNA ligase 35.95 1 17 17 78 6.211E8 82.83 35.95 17 41 5284.51 33.05 16 37 587 65.0 4.35 HVO_0017 conserved hypothetical protein 35.94 1 4 4 20 8.195E7 7.58 35.94 4 10 968.07 35.94 4 10 192 21.9 4.50 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 35.84 1 8 8 48 4.151E8 43.70 35.84 8 24 2989.07 35.84 8 24 226 25.5 4.25 40354192 keratin 10 [Homo sapiens] 35.79 1 0 19 85 5.480E8 79.06 35.62 18 42 5264.11 35.79 19 43 584 58.8 5.16 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 35.56 1 8 8 38 1.573E8 33.93 35.56 8 19 2336.65 35.56 8 19 270 29.1 4.35 HVO_2643 NADPH:quinone reductase 35.55 1 8 8 50 1.387E8 36.44 35.55 8 25 2509.13 35.55 8 25 346 37.2 4.55 HVO_C0001 Orc1-type DNA replication protein 35.54 1 12 12 32 8.978E7 24.43 31.62 11 15 1808.06 35.54 12 17 408 45.2 4.97 HVO_1571 DNA topoisomerase VI subunit B 35.46 1 20 20 71 2.550E8 65.50 33.08 19 36 4987.45 34.46 19 35 798 87.4 4.73 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 35.24 1 0 19 85 5.480E8 79.06 35.08 18 42 5264.11 35.24 19 43 593 59.5 5.21 HVO_0175 DNA polymerase sliding clamp 35.22 1 6 6 83 1.819E9 65.60 35.22 6 42 5101.07 35.22 6 41 247 26.7 4.39 HVO_3014 origin-associated GTP-binding protein OapA 35.21 1 7 7 20 6.751E7 9.59 29.11 5 9 1055.20 35.21 7 11 213 24.0 5.01 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 35.12 1 12 12 65 3.427E8 59.66 35.12 12 33 4264.70 35.12 12 32 447 48.5 4.56 HVO_0787 indole-3-glycerol-phosphate synthase 35.06 1 5 5 9 2.499E7 4.80 30.68 4 4 360.49 35.06 5 5 251 26.7 4.44 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 34.99 1 17 18 75 3.962E8 86.97 33.55 17 37 4819.93 34.99 18 38 623 62.1 5.30 HVO_2227 siroheme decarboxylase AhbA 34.87 1 7 7 23 1.635E8 19.03 34.87 7 12 1287.22 27.09 6 11 347 39.1 4.69 HVO_A0636 YbaK domain protein 34.81 1 3 3 14 9.238E7 20.90 34.81 3 7 1292.51 34.81 3 7 158 16.7 4.54 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 34.63 1 0 25 156 8.918E8 151.21 34.63 25 78 10643.08 34.63 25 78 644 66.0 8.12 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 34.59 1 13 13 97 6.799E8 62.94 34.59 13 49 5714.86 32.43 12 48 370 41.9 4.48 HVO_0729 inorganic pyrophosphatase 34.46 1 7 7 43 8.248E8 47.20 34.46 7 23 2445.02 34.46 7 20 177 20.4 4.16 HVO_A0307 Lrp/AsnC family transcription regulator 34.46 1 5 5 11 4.702E7 9.41 27.68 4 5 709.39 34.46 5 6 177 19.4 4.39 HVO_2740 nucleoside-diphosphate kinase 34.42 1 4 4 31 1.303E8 34.56 34.42 4 16 2598.20 34.42 4 15 154 17.5 4.50 HVO_1778 catalase-peroxidase 34.40 1 15 15 72 8.139E8 76.64 33.29 14 35 4861.91 34.40 15 37 718 80.0 4.31 HVO_2790 ATP-binding protein Mrp 34.39 1 7 7 24 1.925E8 24.70 34.39 7 13 1603.44 29.48 6 11 346 36.8 4.50 HVO_2417 conserved hypothetical protein 34.36 1 5 5 26 2.441E8 17.41 31.28 4 12 1555.07 34.36 5 14 195 21.6 3.65 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 34.27 1 14 14 55 3.446E8 35.75 34.27 14 29 2882.56 32.32 12 26 461 50.7 4.73 HVO_2675 histidinol dehydrogenase 34.11 1 10 10 39 2.425E8 36.30 28.97 9 19 2571.00 34.11 10 20 428 45.4 4.50 HVO_0717 "cell division protein FtsZ, type I" 34.04 1 12 12 71 9.309E8 71.96 34.04 12 35 5098.87 34.04 12 36 379 39.8 4.40 HVO_0979 NADH dehydrogenase-like complex subunit B 33.91 1 7 7 21 1.222E8 14.72 33.91 7 11 1210.64 31.33 6 10 233 26.1 5.01 HVO_2380 AAA-type ATPase (CDC48 subfamily) 33.65 1 19 19 50 9.834E7 36.30 31.49 17 24 2682.59 32.44 18 26 743 81.9 4.82 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 33.63 1 7 7 36 3.347E8 48.54 28.27 6 17 3275.83 33.63 7 19 336 36.8 4.12 HVO_1344 SBDS family protein 33.61 1 5 5 17 3.660E7 12.27 23.11 4 8 973.80 33.61 5 9 238 26.5 4.51 HVO_1783 conserved hypothetical protein 33.48 1 5 5 19 5.039E7 13.41 29.02 4 9 1044.33 33.48 5 10 224 24.1 5.90 HVO_0601 homoserine dehydrogenase 32.91 1 5 6 27 2.699E8 38.62 32.91 6 14 2250.66 31.01 5 13 316 32.2 4.25 HVO_0401 UspA domain protein 32.89 1 4 4 14 2.419E8 7.51 32.89 4 6 700.15 32.89 4 8 152 16.4 4.79 HVO_2436 malic enzyme (NADP) 32.89 1 15 19 95 2.846E8 95.25 32.22 18 48 6307.24 31.69 18 47 751 81.4 4.55 HVO_2716 acyl-CoA dehydrogenase 32.81 1 8 8 36 9.881E7 31.07 30.45 7 17 2434.72 32.81 8 19 381 41.3 4.65 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 32.62 1 10 10 34 7.612E7 35.92 32.62 10 17 2229.30 32.62 10 17 420 45.0 4.86 HVO_2759 peptidase M42 family protein 32.49 1 8 8 37 9.722E7 37.55 32.49 8 19 2166.50 32.49 8 18 354 37.0 4.40 HVO_1867 lysine--tRNA ligase 32.43 1 15 15 45 1.297E8 35.75 32.43 15 23 2732.10 31.35 14 22 555 62.1 4.46 HVO_A0496 UspA domain protein 32.41 1 8 8 45 3.242E8 47.32 32.41 8 23 2861.66 29.31 7 22 290 31.4 4.60 HVO_1573 DNA gyrase subunit A 32.37 1 23 23 99 4.460E8 91.12 32.37 23 50 5921.30 31.21 22 49 862 94.8 4.56 HVO_1148 30S ribosomal protein S15 32.26 1 3 3 6 2.291E7 5.51 32.26 3 3 377.19 32.26 3 3 155 17.5 4.91 HVO_1623 conserved hypothetical protein 32.21 1 6 6 23 1.627E8 17.96 32.21 6 11 1523.40 32.21 6 12 298 32.8 4.56 HVO_2619 ubiquitin-like modifier protein SAMP1 32.18 1 2 2 4 2.653E7 0.00 32.18 2 2 96.53 32.18 2 2 87 8.9 4.26 HVO_C0069 GFO family oxidoreductase 32.10 1 9 9 49 1.013E8 40.79 29.94 8 24 2582.63 32.10 9 25 324 36.0 5.10 HVO_2225 AstE family protein 31.96 1 6 6 27 3.769E8 31.49 31.96 6 13 1891.66 31.96 6 14 341 36.9 4.53 HVO_2947 phenylalanine--tRNA ligase beta subunit 31.93 1 12 12 40 2.833E8 38.35 28.77 10 18 2769.49 31.93 12 22 570 63.3 4.46 HVO_A0133 conserved hypothetical protein 31.85 1 6 6 22 1.790E8 25.11 31.85 6 11 1589.10 31.85 6 11 292 30.8 5.17 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 31.69 1 3 3 16 9.012E7 9.27 31.69 3 8 683.22 31.69 3 8 183 20.0 4.21 HVO_0406 RNA-binding protein AU-1 31.62 1 10 10 35 1.190E8 34.99 31.62 10 18 2055.09 31.62 10 17 468 49.9 4.53 HVO_0573 endonuclease IV 31.62 1 6 6 27 4.066E8 25.40 31.62 6 14 1661.11 27.15 5 13 291 31.4 4.44 HVO_2130 IclR family transcription regulator 31.62 1 7 7 25 1.304E8 16.56 27.57 6 11 1687.28 31.62 7 14 272 30.1 5.55 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 31.61 1 6 6 18 1.062E8 13.66 31.61 6 10 815.18 22.80 5 8 386 42.1 4.49 HVO_2782 30S ribosomal protein S11 31.54 1 4 4 16 1.270E8 13.39 31.54 4 8 871.07 31.54 4 8 130 13.4 8.56 HVO_B0001 Orc1-type DNA replication protein 31.46 1 9 10 28 7.142E7 15.55 27.80 9 13 1413.33 31.46 10 15 410 45.8 5.33 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 12 9.963E8 19.20 31.45 3 6 1081.70 31.45 3 6 124 14.2 5.22 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 31.34 1 3 3 5 2.484E7 3.72 24.63 2 2 269.07 31.34 3 3 134 13.9 4.55 HVO_2948 phenylalanine--tRNA ligase alpha subunit 31.26 1 8 8 37 3.194E8 36.15 24.05 7 19 2021.02 31.26 8 18 499 55.1 4.41 HVO_1097 diaminopimelate epimerase 31.25 1 6 6 26 8.176E7 27.95 27.78 5 12 1762.94 31.25 6 14 288 29.9 4.48 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 31.23 1 8 8 33 1.383E8 35.23 29.13 7 15 2514.87 31.23 8 18 333 36.7 4.56 HVO_2712 3'-5' RNA ligase 31.07 1 12 12 36 1.416E8 24.63 28.40 10 17 2031.28 31.07 12 19 486 53.4 4.92 HVO_2547 50S ribosomal protein L32e 31.06 1 6 6 25 1.477E8 20.94 23.83 5 11 1873.90 31.06 6 14 235 25.8 4.75 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 31.06 1 14 14 60 2.303E8 53.26 31.06 14 30 3145.39 31.06 14 30 615 67.6 4.88 HVO_1332 conserved hypothetical protein 31.01 1 4 4 14 1.748E8 10.57 22.48 3 6 994.03 31.01 4 8 129 14.9 4.16 HVO_0697 PAC2 family protein 30.98 1 4 4 23 2.421E8 33.94 30.98 4 12 2029.19 30.98 4 11 255 27.4 4.08 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 30.91 1 9 9 36 1.899E8 19.71 30.91 9 17 1920.67 30.91 9 19 427 45.4 4.56 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 41 4.931E8 49.90 30.84 8 21 2684.07 30.84 8 20 415 44.4 4.41 HVO_1488 D-gluconate dehydratase 30.83 1 9 11 71 9.025E8 72.07 30.83 11 35 4786.05 30.83 11 36 412 45.8 4.60 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 30.80 1 10 10 53 7.826E8 47.33 30.80 10 27 3520.84 29.20 9 26 435 46.9 4.63 HVO_1576 NAD-dependent epimerase/dehydratase 30.72 1 4 8 46 5.123E8 34.27 30.72 8 23 2955.72 30.72 8 23 306 33.9 4.51 HVO_0868 NAD-dependent epimerase/dehydratase 30.70 1 9 9 21 7.368E7 6.34 28.88 8 11 832.52 21.88 7 10 329 36.1 4.55 HVO_0549 2-keto-3-deoxygluconate kinase 30.63 1 8 9 36 2.456E8 29.58 26.88 8 18 2532.37 28.75 8 18 320 34.1 4.34 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 30.59 1 26 26 129 5.367E8 125.11 29.11 25 64 9426.66 30.59 26 65 1082 117.2 4.32 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 30.55 1 13 13 70 3.552E8 70.18 30.55 13 36 4575.90 28.84 12 34 586 63.4 4.70 HVO_2781 DNA-directed RNA polymerase subunit D 30.50 1 6 6 33 6.376E8 34.91 26.25 5 16 2833.11 30.50 6 17 259 28.1 4.32 HVO_1531 UDP-glucose 6-dehydrogenase 30.47 1 12 12 49 1.476E8 41.60 30.47 12 25 2954.15 30.47 12 24 430 45.9 4.50 HVO_1654 cysteine synthase 30.39 1 7 7 26 2.061E8 27.33 30.39 7 13 1849.42 30.39 7 13 306 32.3 4.32 HVO_1570 DNA topoisomerase VI subunit A 30.33 1 8 8 25 1.967E8 17.61 25.96 6 12 1672.95 30.33 8 13 366 41.8 4.63 HVO_0350 DNA-directed RNA polymerase subunit A'' 30.31 1 12 12 55 1.029E9 62.08 30.31 12 28 3692.29 29.12 11 27 419 46.1 4.35 HVO_2496 adenylate kinase 30.29 1 5 5 23 6.031E8 31.93 30.29 5 12 1740.56 30.29 5 11 208 23.1 4.25 HVO_B0061 precorrin-2 C20-methyltransferase 30.21 1 5 5 18 7.197E7 14.27 30.21 5 9 795.03 30.21 5 9 235 25.3 4.63 HVO_1506 ketol-acid reductoisomerase 30.17 1 6 6 42 6.430E8 49.58 30.17 6 21 3220.94 30.17 6 21 348 37.9 4.34 HVO_0400 conserved hypothetical protein 30.16 1 2 2 8 6.207E7 7.55 30.16 2 4 611.91 30.16 2 4 126 13.9 4.68 HVO_1871 UPF0447 family protein 30.14 1 12 12 54 3.215E8 44.62 26.75 11 26 3231.53 30.14 12 28 501 56.1 4.59 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 29.95 1 9 9 47 2.249E8 52.72 29.95 9 24 3556.96 29.95 9 23 364 39.3 4.35 HVO_1491 HAD superfamily hydrolase 29.90 1 10 10 32 9.475E7 27.36 26.96 9 17 1732.75 26.96 8 15 408 44.4 4.60 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 29.90 1 3 3 14 1.159E8 14.40 29.90 3 7 866.49 29.90 3 7 97 10.8 4.53 HVO_1858 30S ribosomal protein S19e 29.80 1 2 2 4 5.784E7 494.16 29.80 2 4 151 16.7 4.84 HVO_1527 glucose-1-phosphate uridylyltransferase 29.63 1 8 8 41 3.543E8 32.87 29.63 8 21 2253.18 29.63 8 20 243 27.5 4.70 HVO_0876 methylglyoxal synthase 29.13 1 3 3 8 4.171E7 5.92 29.13 3 4 481.63 29.13 3 4 127 13.9 4.48 HVO_1925 probable GTP-binding protein 28.92 1 7 7 25 9.794E7 6.80 28.92 7 13 904.39 28.92 7 12 325 36.5 4.72 HVO_1496 phosphotransferase system component I 28.85 1 13 13 50 1.781E8 37.71 28.85 13 25 2870.87 28.85 13 25 565 60.3 4.21 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 28.77 1 4 4 14 5.809E7 13.19 16.44 3 7 848.79 28.77 4 7 219 22.4 4.06 HVO_1660 DisA-N domain protein 28.62 1 6 6 23 2.520E8 27.65 23.05 5 11 1853.09 28.62 6 12 269 28.9 4.73 HVO_B0114 IclR family transcription regulator 28.57 1 7 7 22 3.268E7 8.14 28.57 7 11 880.72 28.57 7 11 252 28.4 5.44 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 28.47 1 14 14 48 1.026E8 38.90 24.36 12 23 3145.90 28.47 14 25 706 73.3 4.39 HVO_1025 acetyl-CoA C-acyltransferase 28.46 1 10 10 42 4.509E8 34.28 28.46 10 23 2298.37 28.46 10 19 383 40.7 4.56 HVO_2706 translation initiation factor aIF-2B delta subunit 28.37 1 7 7 27 2.121E8 19.21 28.37 7 13 1550.97 25.89 6 14 282 30.7 4.42 HVO_2861 conserved hypothetical protein 28.36 1 8 8 38 4.415E8 36.52 28.36 8 19 2438.21 28.36 8 19 275 29.1 4.27 HVO_2580 L-aspartate oxidase 28.31 1 11 11 47 1.548E8 24.82 28.31 11 24 2705.15 28.31 11 23 537 55.8 4.63 HVO_2918 thymidylate synthase 28.31 1 5 5 15 7.214E7 11.25 24.10 4 7 989.44 28.31 5 8 332 37.5 4.61 7428712 "keratin 1, type II, cytoskeletal - human" 28.30 1 0 21 142 8.350E8 140.96 28.30 21 71 9824.57 28.30 21 71 643 65.5 6.35 HVO_0452 leucine--tRNA ligase 28.18 1 21 21 88 3.940E8 97.44 28.18 21 44 6860.54 28.18 21 44 958 109.5 4.37 HVO_1568 alpha/beta hydrolase fold protein 28.16 1 6 6 23 3.195E7 18.28 28.16 6 12 1036.19 28.16 6 11 277 29.4 4.94 HVO_B0130 DUF296 family protein 28.15 1 3 3 8 9.617E7 2.24 20.74 2 4 339.30 28.15 3 4 135 14.8 4.41 HVO_0658 tRNA pseudouridine(13) synthase TruD 28.08 1 8 8 30 1.131E8 27.66 28.08 8 15 1976.43 28.08 8 15 463 50.6 4.70 HVO_0357 ACT domain protein 28.04 1 5 5 20 3.213E8 21.84 28.04 5 11 1318.05 28.04 5 9 189 20.2 4.59 HVO_2879 ornithine cyclodeaminase 28.01 1 6 6 22 1.465E8 12.09 20.48 5 10 1195.15 28.01 6 12 332 34.6 4.45 HVO_0812 phosphoenolpyruvate synthase 27.99 1 18 18 74 1.528E8 69.93 27.99 18 37 4608.80 27.99 18 37 761 83.1 4.63 HVO_2708 YfiH family protein 27.95 1 6 6 22 3.234E8 33.09 27.95 6 11 2018.39 27.95 6 11 322 35.4 4.35 HVO_1957 proteasome-activating nucleotidase 27.91 1 8 8 28 1.223E8 19.20 27.91 8 14 1246.15 27.91 8 14 412 45.6 4.48 HVO_A0266 IclR family transcription regulator 27.84 1 6 6 29 9.161E7 18.62 27.84 6 15 1447.73 27.84 6 14 255 27.7 6.05 HVO_1020 HEAT-PBS family protein 27.68 1 9 9 32 1.948E8 34.02 23.39 8 16 2798.89 27.68 9 16 419 45.5 3.95 HVO_1577 conserved hypothetical protein 27.68 1 4 4 21 2.619E8 29.97 23.16 3 10 1718.52 27.68 4 11 177 19.4 4.74 HVO_1967 glucose-6-phosphate isomerase 27.67 1 9 9 37 1.665E8 31.15 27.21 8 18 2672.89 25.58 8 19 430 45.6 4.40 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 27.66 1 3 3 12 1.677E8 6.57 27.66 3 6 474.59 27.66 3 6 188 20.5 4.60 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 27.62 1 9 9 33 1.144E8 22.12 24.42 8 15 2347.56 27.62 9 18 344 39.1 4.73 HVO_2239 UspA domain protein 27.46 1 5 5 18 3.016E8 16.27 27.46 5 9 1189.21 27.46 5 9 142 15.4 4.16 HVO_2481 HD family hydrolase 27.44 1 7 7 15 6.351E7 5.33 24.10 6 8 424.20 24.62 6 7 390 42.7 6.14 HVO_1866 uridylate kinase 27.43 1 5 5 28 3.408E8 20.19 27.43 5 14 1686.77 24.47 4 14 237 24.6 4.42 HVO_1125 cysteine--tRNA ligase 27.33 1 10 10 43 2.176E8 47.43 27.33 10 22 3014.55 27.33 9 21 494 55.2 4.56 HVO_1250 redoxin domain protein 27.27 1 2 2 6 1.570E7 7.37 27.27 2 3 563.90 27.27 2 3 187 20.5 4.03 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 27.21 1 9 9 38 1.226E8 35.61 27.21 9 19 1752.50 27.21 9 19 430 45.1 4.50 HVO_0429 archaemetzincin 27.17 1 3 3 7 6.634E7 6.90 17.92 2 3 503.34 27.17 3 4 173 19.3 6.54 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 27.17 1 6 6 22 8.350E7 19.07 27.17 6 11 1435.84 27.17 6 11 265 28.7 4.87 HVO_1295 histidinol-phosphate aminotransferase 27.15 1 7 7 23 1.015E8 18.50 27.15 7 12 1419.93 20.78 6 11 361 39.4 4.51 HVO_0916 diphthine synthase 27.14 1 6 6 21 2.965E8 15.73 27.14 6 10 1210.14 27.14 6 11 269 29.1 4.54 HVO_1593 PAC2 family protein 27.02 1 5 5 16 9.297E7 12.18 27.02 5 8 773.46 27.02 5 8 248 26.6 4.46 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 26.92 1 4 4 24 1.080E8 31.54 26.92 4 12 1877.99 26.92 4 12 208 22.6 4.36 HVO_1508 acetolactate synthase large subunit 26.92 1 10 10 40 2.969E8 48.26 26.92 10 20 2995.54 26.92 10 20 587 62.3 4.36 HVO_1371 glutamate 5-kinase 26.91 1 7 7 27 3.747E8 32.15 25.25 6 13 2409.37 26.91 7 14 301 32.0 4.25 HVO_2313 siroheme decarboxylase AhbB 26.91 1 7 7 28 2.185E8 31.67 25.50 6 14 1961.13 26.91 7 14 353 39.6 4.64 HVO_2018 conserved hypothetical protein 26.89 1 3 3 5 1.702E7 3.42 15.97 2 2 271.15 26.89 3 3 119 13.4 4.73 HVO_0795 transcription initiation factor TFB 26.87 1 5 8 30 1.953E8 30.01 26.87 8 15 2022.49 26.87 8 15 335 37.4 5.59 HVO_0122 phosphoglycerate dehydrogenase 26.85 1 6 6 23 1.150E8 25.65 22.53 5 11 1626.22 26.85 6 12 324 35.3 5.35 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 26.83 1 6 6 28 6.571E7 24.18 26.83 6 14 1544.99 26.83 6 14 287 31.8 4.93 HVO_1478 transcription initiation factor TFB 26.81 1 5 8 50 3.451E8 51.95 26.81 8 25 3701.79 26.81 8 25 317 35.7 5.47 HVO_2383 DNA repair and recombination protein RadB 26.64 1 5 5 21 6.823E7 27.46 26.64 5 11 1499.51 26.64 5 10 229 24.6 5.02 HVO_0997 peptidase M24 family protein 26.63 1 6 6 21 6.657E7 20.09 26.63 6 11 1417.44 26.63 6 10 368 39.9 4.49 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 26.59 1 6 6 26 6.012E8 30.37 26.59 6 13 2067.35 26.59 6 13 252 26.0 4.39 HVO_2639 DUF1611 family protein 26.39 1 6 6 28 2.474E8 30.40 26.39 6 14 1765.29 26.39 6 14 341 36.3 4.44 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 26.22 1 10 10 36 1.859E8 32.59 26.22 10 17 2065.71 26.22 10 19 473 50.8 4.58 HVO_1847 oligoendopeptidase PepF 26.21 1 11 11 40 1.327E8 39.37 26.21 11 21 2203.66 22.04 10 19 599 68.5 4.41 HVO_0681 DNA topoisomerase I 26.19 1 16 16 56 1.274E8 52.91 26.19 16 28 3723.85 25.36 15 28 840 93.6 4.58 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 25.90 1 4 4 11 6.577E7 10.29 25.90 4 6 642.93 16.39 3 5 305 32.7 4.56 HVO_2951 tryptophan--tRNA ligase 25.90 1 8 8 19 1.005E8 3.96 17.39 6 9 555.06 20.79 6 10 529 59.1 4.53 HVO_0466 citrate (si)-synthase 25.86 1 8 8 55 5.046E8 69.74 25.86 8 28 4192.10 25.86 8 27 379 41.8 4.55 HVO_1327 AAA-type ATPase (CDC48 subfamily) 25.82 1 12 13 41 1.355E8 30.69 25.82 13 21 2196.10 22.83 11 20 736 78.1 4.88 HVO_0551 DNA mismatch repair protein MutL 25.71 1 12 12 33 5.981E7 25.28 24.49 11 16 2117.89 25.71 12 17 735 78.7 4.50 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 25.68 1 16 16 74 4.893E8 67.12 24.68 15 37 5582.73 24.68 15 37 697 74.5 4.13 HVO_1337 rpa-associated protein 25.68 1 11 11 36 2.883E8 28.34 20.87 10 17 1827.69 25.68 11 19 623 64.8 3.68 HVO_1816 dihydroorotase 25.64 1 6 6 20 8.609E7 25.23 25.64 6 10 1544.76 25.64 6 10 429 45.4 4.40 HVO_0214 L-lactate dehydrogenase 25.62 1 9 9 47 1.476E9 40.57 25.62 9 22 3204.50 25.62 9 25 320 34.5 4.49 HVO_2965 phosphoserine phosphatase 25.58 1 4 4 9 2.469E7 9.59 19.53 3 4 509.03 25.58 4 5 215 23.2 4.51 HVO_A0331 D-galactonate dehydratase 25.52 1 6 6 22 1.106E8 16.27 24.22 5 11 1078.06 25.52 6 11 384 42.8 4.83 HVO_1291 fumarylacetoacetase family protein 25.51 1 4 4 16 3.409E8 12.12 25.51 4 8 892.51 25.51 4 8 243 26.3 4.55 HVO_2068 "FtsZ family protein, type III" 25.41 1 5 5 26 1.742E8 27.00 25.41 5 13 1905.08 25.41 5 13 370 38.7 4.49 HVO_1579 uridine phosphorylase 25.37 1 4 4 9 7.811E7 3.98 25.37 4 5 324.79 17.65 3 4 272 29.0 4.64 HVO_C0077 sarcosine oxidase 25.32 1 5 5 18 5.531E7 19.45 25.32 5 9 1265.48 25.32 5 9 387 42.9 4.70 HVO_1727 TATA-binding transcription initiation factor 25.27 1 5 5 22 5.926E8 17.45 25.27 5 11 1518.49 25.27 5 11 186 19.9 4.36 HVO_2205 arNOG06768 family NADH-binding domain protein 25.25 1 5 5 18 5.686E7 25.62 25.25 5 9 1479.80 25.25 5 9 301 32.0 5.00 HVO_1048 phosphoribosylformylglycinamidine synthase 2 25.21 1 12 12 69 5.344E8 77.90 24.22 11 33 5685.17 25.21 12 36 702 72.9 4.18 HVO_2945 valine--tRNA ligase 25.17 1 18 18 71 3.984E8 55.39 23.68 16 36 4437.01 17.93 15 35 870 98.9 4.36 >sp|TRYP_PIG| 25.11 1 4 4 63 1.432E10 68.06 25.11 4 31 4873.32 25.11 4 32 231 24.4 7.18 HVO_B0018 ParA domain protein 25.09 1 3 3 11 6.124E7 7.02 25.09 3 5 649.48 25.09 3 6 287 31.7 4.74 HVO_2008 archaeosine synthase 24.96 1 11 11 38 2.790E8 23.25 24.96 11 19 2159.83 24.96 11 19 585 64.9 4.81 HVO_1079 sulfate adenylyltransferase small subunit 24.92 1 7 7 23 2.324E8 21.64 23.08 6 11 1465.91 24.92 7 12 325 37.5 4.18 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 24.84 1 10 10 25 5.766E7 20.64 24.84 10 13 1391.58 23.53 9 12 459 50.5 4.63 HVO_2995 ferredoxin (2Fe-2S) 24.81 1 2 2 4 5.216E7 0.00 24.81 2 4 129 14.4 3.98 HVO_0123 signal recognition particle 54K protein 24.73 1 10 10 34 1.853E8 28.98 22.58 9 17 2300.91 21.72 8 17 465 50.9 4.50 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 24.66 1 7 7 34 4.193E8 27.44 24.66 7 17 1905.89 24.66 7 17 373 40.2 4.44 HVO_0970 ribulose-bisphosphate carboxylase large subunit 24.64 1 9 9 40 1.674E8 36.88 24.64 9 20 2610.19 24.64 9 20 414 43.9 4.59 HVO_0894 acyl-CoA synthetase 24.47 1 5 12 38 1.173E8 31.81 22.96 11 17 2224.36 24.47 12 21 662 74.3 4.48 HVO_0536 ferritin 24.43 1 2 2 12 1.062E8 21.21 24.43 2 6 953.66 24.43 2 6 176 19.9 4.50 HVO_1575 arginase 24.41 1 5 5 14 1.147E8 8.72 24.41 5 7 707.28 24.41 5 7 299 31.0 4.58 HVO_1547 isoleucine--tRNA ligase 24.35 1 16 16 96 4.985E8 92.13 21.48 15 48 5643.99 24.35 16 48 1043 117.9 4.30 HVO_2665 HpcH/HpaI aldolase family protein 24.15 1 5 5 16 6.711E7 14.32 24.15 5 8 830.21 24.15 5 8 265 28.3 4.50 HVO_2717 alanine--tRNA ligase 24.12 1 8 8 21 1.112E8 14.47 21.11 7 10 1225.23 17.59 6 11 398 41.6 4.39 HVO_2562 50S ribosomal protein L23 24.10 1 2 2 6 3.326E7 7.35 24.10 2 3 558.58 24.10 2 3 83 9.4 5.48 HVO_2960 dihydrolipoamide S-acyltransferase 23.99 1 10 10 42 1.364E8 39.03 23.99 10 21 3110.50 23.99 10 21 521 54.9 4.40 HVO_0769 TRAM domain protein 23.88 1 3 3 9 2.840E7 4.86 23.88 3 4 489.89 23.88 3 5 134 14.8 4.32 HVO_2648 phosphoglycerate dehydrogenase 23.82 1 5 6 19 7.051E7 12.06 21.00 5 10 1211.64 21.63 5 9 319 34.2 4.64 HVO_0552 DNA mismatch repair protein MutS 23.59 1 17 17 50 1.254E8 36.03 22.08 15 24 2631.61 21.65 16 26 924 99.2 4.65 HVO_0048 argininosuccinate lyase 23.57 1 8 8 26 9.621E7 22.04 21.72 7 14 1607.90 21.52 7 12 488 50.8 4.53 HVO_1175 DUF2110 family protein 23.56 1 5 5 24 3.951E8 22.78 23.56 5 12 1633.58 23.56 5 12 225 24.4 4.63 HVO_A0388 Lrp/AsnC family transcription regulator 23.56 1 3 3 11 2.409E7 6.85 23.56 3 5 501.60 23.56 3 6 174 20.1 4.86 HVO_1918 probable metallo-beta-lactamase family hydrolase 23.51 1 3 3 10 4.218E7 10.48 23.51 3 5 598.44 23.51 3 5 302 34.0 4.55 HVO_2662 homolog to lactoylglutathione lyase 23.40 1 5 5 16 8.633E7 9.51 23.40 5 8 935.00 23.40 5 8 329 36.5 4.48 HVO_2564 50S ribosomal protein L3 23.37 1 6 6 25 1.003E8 26.37 23.37 6 12 1917.67 23.37 6 13 338 37.2 6.68 HVO_2536 CHP00300 family protein 23.32 1 6 6 26 7.518E7 11.89 23.32 6 13 1134.15 23.32 6 13 416 44.8 4.51 HVO_0484 50S ribosomal protein L10e 23.30 1 3 3 14 1.099E8 18.65 23.30 3 7 1011.60 23.30 3 7 176 19.8 8.72 HVO_1348 probable YjeF family carbohydrate kinase 23.22 1 9 9 31 7.010E7 30.97 23.22 9 16 1940.98 23.22 9 15 478 48.8 4.45 HVO_1725 Orc1-type DNA replication protein 23.19 1 6 7 15 4.348E7 13.20 18.70 5 6 1310.48 23.19 7 9 401 44.5 5.19 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 23.08 1 6 6 26 1.850E8 21.71 23.08 6 13 1753.36 23.08 6 13 377 39.2 4.18 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 23.06 1 8 8 33 1.275E8 22.86 23.06 8 17 1588.27 19.40 7 16 464 53.1 4.54 HVO_1567 conserved hypothetical protein 22.98 1 4 4 11 1.346E8 11.89 22.98 4 6 743.32 16.60 3 5 235 25.7 4.36 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 22.98 1 24 24 85 1.566E8 72.99 22.98 24 42 4567.39 22.98 24 43 1284 141.2 4.35 HVO_2908 dihydropteroate synthase 22.96 1 6 6 13 5.755E7 7.76 22.96 6 7 565.71 17.41 5 6 379 40.8 4.53 HVO_2784 30S ribosomal protein S13 22.75 1 3 3 8 1.119E8 6.73 22.75 3 4 508.65 22.75 3 4 167 18.9 5.17 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 22.74 1 6 6 18 1.114E8 12.02 21.37 5 8 1017.37 22.74 6 10 365 39.0 4.61 HVO_2348 GTP cyclohydrolase MptA 22.73 1 6 6 39 2.832E8 19.37 22.73 6 20 1448.97 22.73 6 19 308 33.5 4.68 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 22.72 1 6 7 25 6.230E7 21.14 20.37 6 13 1223.69 22.72 7 12 383 42.0 4.49 HVO_1459 ThuA family protein 22.69 1 3 3 18 2.875E8 30.70 22.69 3 9 1739.11 22.69 3 9 238 26.8 4.67 HVO_1880 conserved hypothetical protein 22.67 1 5 5 20 5.681E7 20.32 22.67 5 10 1501.03 22.67 5 10 225 23.8 4.59 HVO_2529 probable oxidoreductase (short-chain dehydrogenase family) 22.61 1 4 4 10 5.742E7 8.85 22.61 4 5 659.31 22.61 4 5 230 23.6 4.72 HVO_0360 30S ribosomal protein S10 22.55 1 2 2 8 9.494E7 9.83 22.55 2 4 630.74 22.55 2 4 102 11.5 4.88 HVO_B0127 oxidoreductase (luciferase family protein) 22.40 1 5 5 16 4.513E7 10.26 22.40 5 8 636.41 22.40 5 8 317 35.7 4.60 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 22.39 1 5 5 20 4.113E7 18.60 22.39 5 10 1409.83 22.39 5 10 268 27.9 4.87 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 22.38 1 4 4 10 1.000E8 9.18 18.41 3 4 927.00 22.38 4 6 277 30.6 4.30 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 22.28 1 5 5 10 3.453E7 3.50 18.73 4 5 429.27 10.63 3 5 395 42.4 4.54 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 22.28 1 3 3 8 7.235E7 11.76 22.28 3 4 645.99 22.28 3 4 184 19.8 5.30 HVO_1172 NAD-dependent epimerase/dehydratase 22.22 1 6 6 30 5.661E8 21.47 19.68 5 13 2468.50 22.22 6 17 315 34.9 4.34 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 22.22 1 4 4 20 1.792E8 18.78 22.22 4 10 1484.21 22.22 4 10 324 33.6 3.99 HVO_0234 conserved hypothetical protein 22.18 1 3 3 12 5.671E7 14.96 22.18 3 6 695.12 22.18 3 6 275 28.1 4.48 HVO_B0371 aldehyde dehydrogenase 22.18 1 6 6 24 7.317E7 24.96 22.18 6 12 1951.25 22.18 6 12 496 52.5 4.39 HVO_1804 nicotinate phosphoribosyltransferase 22.16 1 7 7 22 1.395E8 23.76 19.07 6 10 1599.27 22.16 7 12 388 41.1 4.60 HVO_1657 phosphoribosylamine--glycine ligase 21.96 1 10 10 55 7.532E8 32.59 21.96 10 26 3444.38 21.96 10 29 428 45.5 4.20 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 21.91 1 5 5 25 7.636E7 17.39 15.43 4 12 1422.37 21.91 5 13 324 36.6 4.68 HVO_2168 AAA-type ATPase (MoxR subfamily) 21.88 1 5 5 15 8.375E7 19.75 19.15 4 7 990.01 21.88 5 8 329 35.9 4.54 HVO_2952 tRNA-splicing endonuclease 21.83 1 5 5 15 6.037E7 7.86 21.83 5 8 497.37 21.83 5 7 339 37.4 4.74 HVO_0699 translation initiation factor aIF-2 alpha subunit 21.80 1 5 5 27 2.816E8 21.39 21.80 5 13 1607.36 21.80 5 14 266 29.5 4.46 HVO_1574 NUDIX family hydrolase 21.79 1 2 2 6 1.291E7 5.30 21.79 2 3 360.52 21.79 2 3 156 17.6 4.98 HVO_0867 HD family hydrolase 21.74 1 5 5 22 8.446E7 19.27 21.74 5 11 1296.27 21.74 5 11 230 26.2 4.78 HVO_2256 DUF262 family protein 21.65 1 11 11 39 1.715E8 25.55 21.65 11 20 2067.06 21.65 11 19 462 54.9 4.89 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 21.53 1 5 5 18 1.207E8 24.93 21.53 5 9 1482.90 21.53 5 9 339 38.1 4.50 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 21.51 1 8 8 24 1.667E8 18.37 21.51 8 12 1277.36 21.51 8 12 423 43.9 4.31 HVO_1914 acetyl-CoA C-acyltransferase 21.49 1 6 6 17 8.309E7 6.95 18.83 5 8 834.20 19.10 5 9 377 39.9 4.41 HVO_1098 diaminopimelate decarboxylase 21.45 1 7 7 22 1.577E8 14.07 21.45 7 11 934.03 20.00 6 11 415 44.4 5.02 HVO_1932 2-D-hydroxyacid dehydrogenase 21.43 1 5 5 21 1.098E8 17.58 21.43 5 10 1271.06 21.43 5 11 308 33.0 4.60 HVO_2543 50S ribosomal protein L30 21.43 1 3 3 8 2.671E7 2.02 21.43 3 4 235.98 21.43 3 4 154 17.1 4.77 HVO_A0486 hydrogenase expression/formation protein 21.43 1 4 4 12 3.632E7 9.50 21.43 4 6 809.99 21.43 4 6 336 33.8 4.06 HVO_0837 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 21.40 1 4 4 8 1.606E7 6.94 11.93 2 3 515.90 21.40 4 5 243 24.8 4.48 HVO_0054 glycine--tRNA ligase 21.38 1 8 8 34 7.725E8 41.54 19.02 7 16 2991.86 21.38 8 18 594 64.9 4.21 HVO_1453 glutamate dehydrogenase (NADP) 21.34 1 7 7 27 1.866E8 16.49 21.34 7 13 1526.64 21.34 7 14 417 45.7 4.49 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 21.31 1 5 5 13 5.990E7 9.37 17.70 4 6 531.17 21.31 5 7 305 34.1 4.91 HVO_0937 FMN-binding domain protein 21.23 1 2 2 8 3.059E7 5.91 21.23 2 4 472.02 21.23 2 4 146 16.2 4.36 HVO_0156 "tRNA (guanine(10),N(2))-dimethyltransferase" 21.18 1 6 6 18 2.536E7 14.65 21.18 6 9 999.68 21.18 6 9 321 34.2 5.25 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 21.14 1 4 4 12 4.662E7 8.00 21.14 4 6 500.77 21.14 4 6 175 18.8 4.63 HVO_0194 Orc1-type DNA replication protein 21.12 1 8 8 27 5.511E7 16.80 21.12 8 14 1224.94 21.12 8 13 374 42.2 4.94 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 21.09 1 4 4 12 4.277E7 8.92 21.09 4 6 575.32 21.09 4 6 294 32.5 4.75 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 21.01 1 5 5 23 3.496E8 15.28 21.01 5 12 1441.79 21.01 5 11 357 39.8 4.41 HVO_A0465 TetR family transcription regulator 20.95 1 3 3 9 1.357E7 9.42 20.95 3 5 364.61 12.86 2 4 210 23.7 4.48 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 20.80 1 6 6 15 3.829E7 10.26 17.13 5 6 1040.62 20.80 6 9 327 36.0 4.73 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 20.75 1 6 6 45 3.683E8 44.37 17.58 5 23 2826.69 20.75 6 22 347 36.8 4.93 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 4 1.600E7 3.77 20.71 2 2 288.92 20.71 2 2 140 16.0 5.57 HVO_0826 peptidase M42 family protein 20.69 1 4 4 20 4.234E7 18.68 20.69 4 10 1299.18 20.69 4 10 348 37.7 4.54 HVO_2636 PspA domain protein 20.65 1 5 5 15 2.749E7 15.07 17.39 4 7 1084.83 20.65 5 8 276 30.9 4.61 HVO_2229 flavin-containing amine-oxidoreductase 20.64 1 6 6 16 4.229E7 12.42 20.64 6 9 571.20 14.83 4 7 344 37.9 4.92 HVO_1134 conserved hypothetical protein 20.61 1 13 13 56 1.525E8 57.66 20.61 13 28 3589.77 20.61 13 28 757 80.6 4.35 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 20.60 1 3 4 14 6.085E7 13.48 20.60 4 7 827.85 20.60 4 7 267 28.8 4.55 HVO_2412 Lrp/AsnC family transcription regulator 20.50 1 3 3 9 3.769E7 8.43 20.50 3 5 579.52 20.50 3 4 161 17.7 4.55 HVO_0854 DNA double-strand break repair ATPase Rad50 20.49 1 16 16 56 4.861E7 49.09 20.49 16 28 3411.80 20.49 16 28 893 100.0 4.58 HVO_2554 50S ribosomal protein L14 20.45 1 3 3 10 9.684E7 5.27 20.45 3 5 516.34 20.45 3 5 132 14.2 9.76 HVO_1058 TrkA domain protein 20.22 1 8 8 21 1.071E8 15.51 20.22 8 11 1158.96 20.22 8 10 445 47.7 4.35 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 20.22 1 3 4 15 1.351E8 8.39 20.22 4 8 630.72 20.22 4 7 267 29.1 4.63 HVO_0042 acetylornithine deacetylase 20.21 1 6 6 16 2.131E8 11.88 20.21 6 8 829.78 20.21 6 8 381 41.0 4.34 HVO_B0382 TATA-binding transcription initiation factor 20.21 1 3 3 12 3.986E7 11.13 20.21 3 6 801.57 20.21 3 6 188 20.1 4.12 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 20.16 1 5 5 24 2.393E8 10.78 15.42 4 11 1354.37 20.16 5 13 253 26.0 4.60 HVO_2707 GFO family oxidoreductase 20.16 1 6 6 22 1.885E8 31.31 20.16 6 11 1780.50 20.16 6 11 372 41.0 4.55 HVO_2266 hypothetical protein 19.88 1 8 8 34 1.456E8 27.06 19.88 8 16 2239.24 19.88 8 18 493 56.7 4.54 HVO_2614 uridine phosphorylase 19.83 1 4 4 14 4.920E8 12.01 19.83 4 7 973.99 19.83 4 7 242 25.8 4.30 HVO_2183 aldehyde ferredoxin oxidoreductase 19.75 1 9 9 27 4.401E7 17.84 15.40 7 11 1458.48 19.75 9 16 643 69.3 4.59 HVO_0745 "FtsZ family protein, type III" 19.72 1 4 4 10 2.410E7 7.51 19.72 4 5 587.64 19.72 4 5 360 37.1 4.51 HVO_2777 30S ribosomal protein S9 19.70 1 3 3 10 2.742E7 6.40 15.15 2 4 538.95 19.70 3 6 132 14.7 9.74 HVO_1299 HTH domain protein 19.65 1 3 3 10 4.145E7 6.98 19.65 3 5 695.41 19.65 3 5 173 18.9 4.84 HVO_2467 NADPH:quinone reductase 19.63 1 5 5 24 1.420E8 23.83 19.63 5 12 1540.58 19.63 5 12 321 33.0 4.51 HVO_0179 Lrp/AsnC family transcription regulator / TrkA domain protein 19.54 1 4 4 12 5.542E7 10.93 19.54 4 6 631.52 19.54 4 6 261 28.0 4.58 HVO_0120 signal recognition particle receptor FtsY 19.52 1 6 6 16 6.253E7 17.15 19.52 6 9 1102.86 17.54 5 7 456 48.2 4.17 HVO_0220 ATP-dependent DNA helicase MCM 19.37 1 12 12 39 4.606E7 32.68 19.37 12 20 2291.97 19.37 12 19 702 78.8 4.73 HVO_2108 IclR family transcription regulator 19.37 1 4 4 6 1.977E7 2.92 10.67 2 2 275.04 19.37 4 4 253 28.0 5.74 HVO_1179 homolog to NAD kinase 19.21 1 4 4 11 6.157E7 6.36 12.99 3 5 536.13 19.21 4 6 354 36.7 4.60 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 19.13 1 5 5 18 6.711E7 19.11 19.13 5 9 1311.08 19.13 5 9 345 36.9 4.68 HVO_A0452 UspA domain protein 19.11 1 4 4 8 2.135E7 3.35 19.11 4 4 302.79 19.11 4 4 293 31.3 4.63 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 18.99 1 4 4 14 1.163E8 14.51 18.99 4 7 979.30 18.99 4 7 237 25.4 4.46 HVO_1289 OsmC domain protein 18.94 1 2 2 20 5.576E8 29.42 18.94 2 10 2634.69 18.94 2 10 132 14.2 3.85 HVO_1356 sensor box histidine kinase 18.91 1 7 7 20 8.422E7 8.34 17.45 6 9 754.13 18.91 7 11 550 61.1 4.60 HVO_0034 acyl-CoA thioester hydrolase 18.90 1 3 3 22 1.389E8 16.11 18.90 3 11 1289.02 18.90 3 11 164 18.3 4.65 HVO_C0042 helicase domain protein 18.76 1 20 20 66 1.474E8 58.96 18.76 20 34 4290.49 17.27 19 32 1274 144.4 4.67 HVO_0195 ribose-5-phosphate isomerase 18.70 1 4 4 14 1.022E8 13.32 18.70 4 7 886.21 18.70 4 7 230 23.2 4.54 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 18.61 1 5 5 29 2.118E8 18.53 15.56 4 13 1845.16 18.61 5 16 360 38.5 4.45 HVO_1553 hydroxypyruvate reductase 18.55 1 6 6 20 4.738E7 11.75 18.55 6 10 1014.67 18.55 6 10 442 45.2 4.50 HVO_2912 ThiJ/PfpI domain protein 18.41 1 2 2 9 5.410E7 7.47 18.41 2 4 424.51 18.41 2 5 201 20.9 4.36 HVO_1648 adenylate cyclase 18.38 1 3 3 7 1.456E7 0.00 18.38 3 3 266.85 18.38 3 4 185 20.5 4.34 HVO_B0115 fumarylacetoacetase family protein 18.37 1 4 4 17 1.163E8 18.31 18.37 4 9 919.91 18.37 4 8 283 30.3 4.21 HVO_1718 "6-carboxy-5,6,7,8-tetrahydropterin synthase" 18.35 1 2 2 6 4.284E7 9.74 18.35 2 3 671.60 18.35 2 3 158 17.1 4.78 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 18 1.282E8 19.72 18.29 4 9 1617.64 18.29 4 9 257 26.8 4.01 HVO_2427 replication factor C large subunit 18.24 1 8 8 26 4.878E7 32.07 18.24 8 13 1988.54 18.24 8 13 488 53.4 4.67 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 18.22 1 1 9 38 3.787E8 38.73 18.22 9 20 2165.76 18.22 9 18 472 51.6 5.16 HVO_1287 PfpI family protease 18.18 1 2 2 4 3.696E7 3.03 18.18 2 2 126.87 18.18 2 2 198 21.5 4.53 HVO_0639 AAA-type ATPase (MoxR subfamily) 18.04 1 5 5 20 5.913E7 11.23 18.04 5 10 1053.28 18.04 5 10 316 34.7 4.89 HVO_0719 transcription elongation factor Spt5/NusG 18.00 1 3 3 8 2.548E7 3.26 14.00 2 3 428.60 18.00 3 5 150 16.3 4.50 HVO_0431 HAD superfamily hydrolase 17.96 1 3 3 9 5.691E7 7.37 17.96 3 5 417.18 6.34 2 4 284 30.4 4.26 HVO_0001 Orc1-type DNA replication protein 17.91 1 8 9 30 3.544E7 28.00 17.91 9 15 1994.56 17.91 9 15 564 62.1 4.39 HVO_1412 diphosphomevalonate decarboxylase 17.90 1 7 7 30 6.454E8 10.47 17.90 7 15 1532.42 17.90 7 15 324 35.4 4.78 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 17.84 1 3 3 12 1.221E8 8.80 17.84 3 6 646.35 17.84 3 6 269 28.3 4.49 HVO_B0256 aldehyde ferredoxin oxidoreductase 17.84 1 8 8 32 6.393E7 31.23 17.84 8 16 1764.08 17.84 8 16 555 59.9 4.55 HVO_1503 3-isopropylmalate dehydratase small subunit 17.82 1 3 3 18 1.390E8 17.06 17.82 3 9 814.90 17.82 3 9 202 22.0 4.15 HVO_0818 threonine synthase 17.74 1 6 6 17 1.358E8 6.44 13.62 5 8 694.06 17.74 6 9 389 40.8 4.31 HVO_1711 glucoamylase 17.54 1 21 21 69 1.056E8 64.11 17.54 21 35 4031.10 16.61 20 34 1511 166.1 4.64 HVO_1625 conserved hypothetical protein 17.43 1 8 8 30 7.695E7 34.28 17.43 8 15 2286.95 17.43 8 15 654 70.1 4.04 HVO_1595 conserved hypothetical protein 17.42 1 2 2 3 2.434E7 174.39 17.42 2 3 178 20.2 4.74 HVO_1979 tRNA pseudouridine synthase Pus10 17.33 1 7 7 31 2.474E8 17.61 15.69 6 15 1878.56 17.33 7 16 427 46.9 4.39 4557890 keratin 5 [Homo sapiens] 17.29 1 0 12 54 2.534E8 49.43 17.29 12 28 3136.12 17.29 12 26 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 17.29 1 0 12 54 2.534E8 49.43 17.29 12 28 3136.12 17.29 12 26 590 62.4 8.06 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 17.21 1 4 4 16 5.012E7 11.39 17.21 4 8 937.15 17.21 4 8 337 35.9 4.69 HVO_2311 glutamyl-tRNA reductase 17.14 1 5 5 15 2.019E7 15.91 17.14 5 7 1040.45 17.14 5 8 461 49.2 4.54 HVO_2347 conserved hypothetical protein 17.14 1 2 2 8 1.664E7 9.48 17.14 2 4 545.84 17.14 2 4 140 15.5 4.37 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 17.05 1 7 7 22 7.639E7 16.94 14.34 6 10 1610.30 17.05 7 12 516 56.7 4.89 HVO_1268 conserved hypothetical protein 16.88 1 3 3 8 3.059E7 5.66 16.88 3 4 549.50 16.88 3 4 237 26.4 5.21 HVO_1995 conserved hypothetical protein 16.87 1 4 4 12 3.425E7 10.78 16.87 4 6 814.22 16.87 4 6 243 26.5 4.39 HVO_0304 electron transfer flavoprotein alpha subunit 16.72 1 3 3 9 5.002E7 13.15 13.56 2 3 1146.32 16.72 3 6 317 33.5 4.18 HVO_1500 1-phosphofructokinase 16.72 1 4 4 12 4.761E7 6.74 16.72 4 6 498.66 16.72 4 6 305 32.0 4.51 HVO_2998 homoserine O-acetyltransferase 16.63 1 4 4 17 4.000E7 13.30 9.88 3 8 1012.65 16.63 4 9 415 44.8 4.69 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 16.62 1 5 5 20 8.900E7 21.71 16.62 5 11 1062.22 16.62 5 9 349 37.0 4.70 HVO_1510 2-isopropylmalate synthase 16.59 1 6 6 25 5.900E8 25.31 16.59 6 13 2100.01 16.59 6 12 440 47.7 4.82 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 16.47 1 0 2 8 5.233E8 5.26 16.47 2 4 336.67 16.47 2 4 85 10.0 5.94 HVO_2501 alpha/beta hydrolase fold protein 16.46 1 4 4 14 3.515E7 9.82 11.71 3 6 775.25 16.46 4 8 316 35.3 5.72 HVO_B0055 conserved hypothetical protein 16.44 1 5 5 11 7.439E7 4.30 16.44 5 6 439.07 16.00 4 5 225 23.9 4.69 HVO_0470 threonine synthase 16.35 1 5 5 13 4.528E7 9.16 16.35 5 7 696.45 12.26 4 6 367 39.2 4.59 HVO_B0117 conserved hypothetical protein 16.35 1 3 3 7 2.426E7 6.43 11.54 2 3 522.21 16.35 3 4 208 23.3 4.58 HVO_0853 DNA double-strand break repair protein Mre11 16.33 1 5 5 13 4.132E7 2.97 16.33 5 6 585.88 16.33 5 7 441 48.1 4.39 HVO_B0375 Spo0M family protein 16.33 1 2 2 8 3.037E7 10.33 16.33 2 4 542.75 16.33 2 4 245 27.2 4.35 HVO_0879 DUF371 family protein 16.31 1 2 2 9 1.825E7 2.03 16.31 2 4 283.55 16.31 2 5 141 15.3 4.65 HVO_A0476 conserved hypothetical protein 16.31 1 5 5 16 2.585E7 5.35 16.31 5 8 716.65 16.31 5 8 331 35.4 4.26 HVO_1878 NAD synthase 16.30 1 4 4 23 1.562E8 20.07 16.30 4 12 1316.18 16.30 4 11 276 29.6 4.37 HVO_A0092 acyl-CoA dehydrogenase 16.27 1 4 4 13 3.624E7 6.16 16.27 4 6 476.83 16.27 4 7 381 42.2 4.83 HVO_0135 RIO-type serine/threonine protein kinase 16.21 1 4 4 14 3.477E7 14.34 16.21 4 7 851.88 16.21 4 7 290 33.0 4.81 HVO_2763 homolog to ribonuclease Z 16.13 1 3 3 14 4.743E7 2.43 16.13 3 7 455.87 16.13 3 7 248 26.6 4.53 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 16.11 1 7 7 26 9.146E7 26.40 16.11 7 13 1922.06 16.11 7 13 658 72.1 4.70 HVO_1629 conserved hypothetical protein 16.01 1 7 7 21 6.443E7 16.59 16.01 7 11 1011.94 14.69 6 10 531 56.3 4.69 HVO_2600 methionyl aminopeptidase 15.88 1 6 6 18 1.036E8 13.77 11.82 5 8 1073.00 15.88 6 10 296 32.3 4.41 HVO_2688 TrmB family transcription regulator 15.86 1 5 5 17 4.263E8 17.42 15.86 5 8 1260.67 15.86 5 9 353 39.3 4.58 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 15.85 1 7 7 28 6.627E7 15.90 15.85 7 14 1384.42 15.85 7 14 492 52.1 4.83 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 15.81 1 15 16 50 8.069E7 31.78 15.81 16 26 2211.90 14.68 15 24 1335 150.5 4.60 HVO_1470 isochorismate synthase 15.80 1 3 4 9 2.783E7 4.07 9.93 2 3 319.98 15.80 4 6 443 47.7 4.56 HVO_1899 DNA-directed RNA polymerase subunit E 15.79 1 3 3 11 4.626E7 6.73 15.79 3 6 491.12 15.79 3 5 190 21.0 4.74 HVO_1374 acyl-CoA synthetase 15.73 1 6 6 16 9.871E7 9.86 15.73 6 8 969.25 13.02 5 8 553 61.1 4.50 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 15.71 1 3 3 7 4.117E7 4.38 8.93 2 3 414.06 15.71 3 4 280 30.0 4.92 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 15.68 1 10 10 24 7.613E7 16.03 13.24 8 12 1068.27 14.46 9 12 740 85.6 4.70 HVO_0043 acetylornithine aminotransferase 15.61 1 4 4 19 5.047E8 13.29 15.61 4 10 1091.98 15.61 4 9 378 39.7 4.67 HVO_0044 acetylglutamate kinase 15.60 1 4 4 14 1.470E8 13.46 15.60 4 7 1150.62 15.60 4 7 327 33.2 4.49 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 15.60 1 3 3 10 4.038E7 8.91 15.60 3 5 447.43 15.60 3 5 327 36.2 4.63 HVO_2913 superoxide dismutase (Mn) 15.58 1 0 3 16 1.328E9 19.47 15.58 3 8 1265.78 15.58 3 8 199 22.3 4.48 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 15.52 1 4 4 12 2.671E7 12.25 15.52 4 6 764.66 15.52 4 6 406 43.1 4.60 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 15.52 1 5 5 14 5.635E7 12.88 15.52 5 7 812.44 15.52 5 7 406 45.5 5.08 HVO_1683 4-alpha-glucanotransferase 15.52 1 5 5 11 4.838E7 4.51 15.52 5 5 405.57 15.52 5 6 496 56.3 4.45 HVO_2001 tRNA-guanine(15) transglycosylase 15.50 1 4 4 14 1.135E8 14.42 15.50 4 7 970.81 15.50 4 7 516 56.3 4.59 HVO_A0475 superoxide dismutase (Mn) 15.50 1 0 3 16 1.328E9 19.47 15.50 3 8 1265.78 15.50 3 8 200 22.4 4.45 HVO_2072 S-layer glycoprotein 15.48 1 5 5 79 8.943E8 69.73 15.48 5 39 3007.62 15.48 5 40 827 85.1 3.65 HVO_1698 CBS/parB domain protein 15.47 1 3 4 13 5.649E7 6.77 15.47 4 6 752.55 15.47 4 7 265 29.4 4.92 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 15.41 1 7 7 50 1.142E9 56.34 15.41 7 25 3419.47 15.41 7 25 357 40.3 4.40 HVO_2581 quinolinate synthase A 15.32 1 5 5 18 1.349E8 13.91 15.32 5 9 912.60 15.32 5 9 385 42.0 4.41 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 15.24 1 3 3 7 3.036E7 4.38 15.24 3 3 299.46 15.24 3 4 328 36.1 4.67 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 15.23 1 2 2 8 4.574E7 5.76 15.23 2 4 237.37 15.23 2 4 348 36.7 4.69 HVO_1391 NUDIX family hydrolase 15.23 1 2 2 6 2.993E7 9.63 15.23 2 3 500.63 15.23 2 3 151 17.4 5.01 HVO_A0087 fumarylacetoacetase family protein 15.22 1 3 3 12 1.691E8 13.40 15.22 3 6 767.25 15.22 3 6 289 32.0 4.21 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 15.18 1 2 2 5 3.338E7 3.80 15.18 2 3 309.37 15.18 2 2 336 36.0 4.51 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 15.15 1 5 5 11 3.212E7 3.55 15.15 5 6 407.53 9.34 4 5 482 50.6 4.31 HVO_A0169 DUF106 family protein 15.08 1 2 2 2 0.000E0 29.04 15.08 2 2 305 33.5 5.24 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 14.94 1 3 3 5 4.144E7 0.00 9.96 2 2 191.98 14.94 3 3 261 27.0 4.44 HVO_0689 chromosome segregation protein Smc 14.92 1 14 14 29 4.576E7 7.56 13.06 11 13 1248.91 14.92 14 16 1240 138.1 4.39 HVO_1501 DeoR family transcription regulator GlpR 14.90 1 3 3 12 2.594E7 15.22 14.90 3 6 767.54 14.90 3 6 255 28.0 4.97 HVO_1087 UspA domain protein 14.89 1 3 3 10 7.303E7 7.75 14.89 3 5 623.07 14.89 3 5 141 15.2 4.98 HVO_1129 conserved hypothetical protein 14.87 1 4 4 13 1.039E8 12.88 14.87 4 6 762.12 14.87 4 7 390 43.0 4.44 HVO_1578 probable NADH dehydrogenase 14.86 1 3 3 12 5.524E7 9.71 14.86 3 6 532.04 14.86 3 6 397 42.8 4.40 HVO_C0054 hypothetical protein 14.83 1 4 4 12 5.424E7 13.08 14.83 4 6 777.40 14.83 4 6 344 37.5 4.70 HVO_1936 F420-0:gamma-glutamyl ligase 14.74 1 3 3 8 4.251E7 7.39 14.74 3 4 421.89 14.74 3 4 251 27.4 4.68 HVO_1656 YyaL family protein 14.65 1 9 9 33 4.234E7 12.03 14.65 9 16 1475.89 14.65 9 17 703 77.3 4.49 HVO_2153 probable copper-containing oxidoreductase 14.55 1 4 4 18 7.592E7 13.46 14.55 4 9 991.73 14.55 4 9 385 42.1 5.82 HVO_0848 endonuclease III 14.54 1 3 3 12 1.752E7 12.34 14.54 3 6 752.89 14.54 3 6 227 25.5 4.55 HVO_1375 O-succinylbenzoic acid--CoA ligase 14.50 1 6 6 18 6.042E7 19.25 14.50 6 9 1073.61 14.50 6 9 614 64.7 4.28 HVO_0233 ribose-phosphate pyrophosphokinase 14.49 1 3 3 12 5.561E7 12.14 14.49 3 6 860.54 14.49 3 6 283 29.6 4.40 HVO_1861 thiamine-monophosphate kinase 14.48 1 4 4 14 2.756E7 14.65 14.48 4 7 906.78 14.48 4 7 297 30.8 4.32 HVO_B0026 probable oxidoreductase (short-chain dehydrogenase family) 14.40 1 2 2 10 4.593E7 5.20 14.40 2 5 328.90 14.40 2 5 257 26.7 4.55 HVO_1823 UspA domain protein 14.38 1 2 2 4 1.866E7 1.80 14.38 2 2 152.28 14.38 2 2 153 16.4 4.60 HVO_0077 uroporphyrin-III C-methyltransferase 14.33 1 3 4 8 1.515E7 1.61 14.33 4 5 196.26 7.17 2 3 293 30.5 4.50 HVO_2702 alpha/beta hydrolase fold protein 14.23 1 3 3 12 7.810E7 8.17 14.23 3 6 741.05 14.23 3 6 260 28.0 4.53 HVO_B0154 receiver/sensor box histidine kinase 14.22 1 14 14 46 6.601E7 31.55 14.22 14 23 2612.47 14.22 14 23 1301 144.1 4.39 HVO_0824 "probable glycosyltransferase, type 1" 14.20 1 4 4 8 2.126E7 3.15 14.20 4 4 334.91 14.20 4 4 352 39.6 5.08 HVO_2456 anthranilate phosphoribosyltransferase 14.20 1 3 3 12 1.413E8 15.88 14.20 3 6 817.41 14.20 3 6 331 33.8 4.35 HVO_B0182 deoxyhypusine synthase 14.20 1 4 4 12 6.180E7 10.46 14.20 4 6 625.40 14.20 4 6 324 35.6 4.30 HVO_0014 ATP-dependent DNA helicase Hel308a 14.15 1 10 10 30 3.988E7 22.82 14.15 10 15 1657.37 14.15 10 15 827 90.3 4.67 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 14.11 1 2 3 8 2.651E7 2.02 14.11 3 4 192.92 11.20 2 4 241 26.1 4.58 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 14.02 1 4 4 14 7.205E7 6.50 14.02 4 7 757.32 14.02 4 7 378 39.8 4.45 HVO_A0550 receiver/sensor box histidine kinase 14.01 1 11 11 35 2.331E7 30.39 14.01 11 18 2234.40 14.01 11 17 885 95.9 4.46 HVO_1187 conserved hypothetical protein 13.99 1 2 2 6 2.130E7 1.87 13.99 2 3 273.51 13.99 2 3 143 16.4 4.86 HVO_1928 5-formyltetrahydrofolate cyclo-ligase 13.99 1 2 2 2 8.473E6 128.91 13.99 2 2 243 26.5 4.69 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 13.93 1 3 3 7 1.103E8 6.96 13.93 3 4 411.41 6.69 2 3 359 39.4 4.91 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 13.91 1 3 3 7 4.635E7 3.75 10.53 2 3 335.27 13.91 3 4 266 29.7 4.32 HVO_2758 50S ribosomal protein L11 13.84 1 2 2 3 9.814E7 518.14 13.84 2 3 159 16.8 4.04 HVO_0712 shikimate dehydrogenase (nonfunctional) 13.75 1 2 2 8 4.295E7 6.62 13.75 2 4 330.58 13.75 2 4 269 27.7 4.65 HVO_1485 conserved hypothetical protein 13.74 1 2 2 6 2.211E7 4.61 13.74 2 3 272.35 13.74 2 3 211 23.0 4.42 HVO_2761 mevalonate kinase 13.62 1 3 3 12 3.938E7 18.72 13.62 3 6 744.75 13.62 3 6 367 38.2 4.31 HVO_2565 conserved hypothetical protein 13.57 1 2 2 2 3.435E7 1.76 13.57 2 2 280 30.3 4.70 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 13.54 1 0 7 37 2.361E8 28.71 13.54 7 19 2105.75 13.54 7 18 384 42.4 5.40 HVO_2160 conserved hypothetical protein 13.51 1 17 17 131 9.603E8 176.73 13.51 17 64 11967.96 13.51 17 67 2257 232.7 3.92 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 13.47 1 4 4 11 4.690E7 6.53 13.47 4 6 481.25 8.90 3 5 438 46.4 4.58 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 13.47 1 4 4 12 3.925E7 9.00 8.63 3 6 652.09 13.47 4 6 475 49.3 4.49 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 13.38 1 5 5 20 1.942E8 20.47 13.38 5 10 1269.96 13.38 5 10 299 32.0 4.53 HVO_1407 HTH domain protein 13.33 1 2 2 6 3.312E7 2.30 13.33 2 3 276.47 13.33 2 3 225 24.9 4.45 HVO_0732 "ribonuclease H, type 1" 13.20 1 3 3 8 1.820E7 5.43 13.20 3 4 344.67 13.20 3 4 197 21.5 5.07 HVO_2747 putative tRNA-specific adenosine deaminase 13.20 1 2 2 6 9.466E6 1.61 13.20 2 3 152.67 13.20 2 3 197 22.3 4.75 HVO_1083 glucose 1-dehydrogenase 13.17 1 2 2 6 4.804E7 3.64 13.17 2 3 260.20 13.17 2 3 357 39.0 4.73 HVO_1741 conserved hypothetical protein 13.11 1 4 4 9 1.340E7 4.32 5.49 2 3 360.65 13.11 4 6 328 37.6 4.46 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 13.08 1 2 2 3 2.157E7 124.76 13.08 2 3 237 26.2 4.70 HVO_B0183 YgeA family protein 13.06 1 3 3 7 1.880E7 0.00 9.80 2 3 301.32 13.06 3 4 245 26.8 4.58 HVO_1864 molybdopterin synthase catalytic subunit 13.03 1 3 3 9 3.849E7 6.27 6.51 2 4 357.28 13.03 3 5 261 27.9 4.41 HVO_A0551 acyl-CoA synthetase 13.01 1 6 6 19 3.693E7 18.35 11.34 5 9 1289.59 13.01 6 10 538 59.6 4.65 HVO_1077 diphthamide biosynthesis protein Dph6 12.92 1 2 2 7 2.852E7 2.54 12.92 2 3 371.11 12.92 2 4 240 26.0 4.15 HVO_B0200 malate synthase 12.84 1 3 3 8 8.453E7 12.72 12.84 3 4 622.69 12.84 3 4 436 48.3 4.30 HVO_B0066 Lrp/AsnC family transcription regulator 12.80 1 2 2 6 2.703E7 8.05 12.80 2 3 353.82 12.80 2 3 164 18.5 4.41 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 12.78 1 6 6 22 8.751E7 14.92 12.78 6 11 1117.07 12.78 6 11 634 66.1 4.54 HVO_A0498 conserved hypothetical protein 12.66 1 4 4 10 4.545E7 0.00 5.01 2 4 421.33 12.66 4 6 379 42.7 4.55 HVO_0675 pantoate kinase 12.64 1 3 3 8 3.325E7 3.65 12.64 3 4 248.68 12.64 3 4 277 27.8 4.54 HVO_0889 FAD-dependent oxidoreductase 12.62 1 2 2 6 7.195E7 7.96 12.62 2 3 558.76 12.62 2 3 214 21.8 3.89 HVO_1354 DNA mismatch repair protein MutS 12.59 1 7 7 16 4.095E7 6.93 11.03 6 7 747.13 12.59 7 9 580 62.1 4.56 HVO_0670 glutathione S-transferase 12.58 1 4 4 15 3.147E7 10.67 12.58 4 7 807.85 12.58 4 8 326 38.1 4.56 HVO_0569 RIO-type serine/threonine protein kinase 12.54 1 3 3 8 1.757E7 9.67 12.54 3 4 505.55 12.54 3 4 303 34.4 4.94 HVO_2004 serine O-acetyltransferase 12.54 1 2 3 11 2.281E8 10.82 12.54 3 6 650.36 12.54 3 5 287 31.9 5.21 HVO_0760 "probable glycosyltransferase, type 2" 12.50 1 4 4 16 3.666E7 8.42 12.50 4 8 866.48 12.50 4 8 368 40.7 4.82 HVO_2697 DNA primase small subunit 12.47 1 4 4 13 1.465E7 7.43 12.47 4 7 526.02 12.47 4 6 385 42.6 4.72 HVO_1594 tRNA/rRNA cytosine-C5-methylase 12.46 1 3 3 11 6.492E7 7.14 12.46 3 6 668.95 12.46 3 5 313 34.6 4.69 HVO_1446 "fructose-1,6-bisphosphatase" 12.46 1 2 2 4 2.436E7 730.88 12.46 2 4 297 31.6 4.45 HVO_0190 TIGR00268 family protein 12.42 1 4 4 11 2.237E7 7.73 9.73 3 5 564.19 12.42 4 6 298 32.5 4.60 HVO_1228 halocyanin 12.42 1 8 8 25 3.765E7 20.28 9.38 7 12 1180.83 12.42 8 13 821 83.7 4.17 HVO_A0156 acyl-CoA synthetase 12.35 1 0 7 24 1.160E8 16.68 12.35 7 11 1273.62 12.35 7 13 664 74.0 4.40 HVO_1716 7-cyano-7-deazaguanine synthase 12.30 1 3 3 10 5.379E7 5.35 12.30 3 5 289.29 12.30 3 5 244 26.8 4.42 HVO_1948 NUDIX family hydrolase 12.30 1 2 2 6 2.356E7 0.00 12.30 2 3 298.43 12.30 2 3 187 20.9 4.45 HVO_1373 acyl-CoA dehydrogenase 12.27 1 3 3 9 1.880E7 6.83 12.27 3 5 456.98 12.27 3 4 383 42.5 4.61 HVO_2888 homolog to elongator complex protein ELP3 12.18 1 6 6 22 4.597E7 16.07 12.18 6 11 1134.30 12.18 6 11 550 62.6 5.01 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 12.04 1 5 5 18 3.408E7 18.49 12.04 5 9 1088.43 12.04 5 9 573 62.9 4.45 HVO_A0003 ParA domain protein 12.04 1 3 3 10 1.990E7 9.03 12.04 3 5 564.42 12.04 3 5 274 30.3 4.53 HVO_0441 probable metallo-beta-lactamase family hydrolase 12.02 1 2 2 4 2.631E7 0.00 12.02 2 2 67.85 12.02 2 2 208 22.7 4.51 HVO_2485 biotin--[acetyl-CoA-carboxylase] ligase 11.98 1 2 2 2 2.354E7 155.37 11.98 2 2 334 35.7 4.75 HVO_A0485 aminotransferase class V 11.97 1 3 3 10 7.517E7 11.48 11.97 3 5 832.08 11.97 3 5 351 37.3 4.26 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 11.85 1 3 3 22 2.261E8 16.79 11.85 3 11 1567.87 11.85 3 11 363 39.7 4.25 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 11.81 1 0 6 23 3.682E8 20.26 11.81 6 12 1300.91 11.81 6 11 432 48.1 5.02 HVO_1565 DNA ligase (ATP) 11.79 1 6 6 19 1.603E7 17.31 11.79 6 9 1236.84 11.79 6 10 585 62.7 4.44 HVO_2891 thymidine kinase 11.79 1 2 2 6 9.375E6 2.18 11.79 2 3 354.51 11.79 2 3 195 21.4 4.63 HVO_0733 transcription initiation factor TFB 11.66 1 1 4 18 3.009E8 19.98 11.66 4 9 1233.98 11.66 4 9 326 37.2 6.00 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 11.66 1 3 3 12 3.325E7 10.59 11.66 3 6 736.40 11.66 3 6 446 47.9 4.39 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 9 1.906E8 5.81 11.64 2 4 488.58 11.64 2 5 189 20.3 4.22 HVO_A0230 peptide methionine sulfoxide reductase MsrA (S-form specific) 11.64 1 2 2 6 4.291E7 1.73 11.64 2 3 211.01 11.64 2 3 189 21.0 4.27 HVO_1073 ThiJ/PfpI family protein 11.61 1 2 2 4 3.258E7 0.00 11.61 2 2 114.32 11.61 2 2 224 23.9 4.12 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 11.55 1 3 3 8 1.890E7 3.84 11.55 3 4 375.91 11.55 3 4 329 36.3 4.49 HVO_1150 IS200-type transposase 11.54 1 2 2 10 3.021E7 6.34 11.54 2 5 485.32 11.54 2 5 130 14.7 5.49 HVO_0768 radical SAM domain protein 11.50 1 3 3 10 2.848E7 8.96 11.50 3 5 449.02 11.50 3 5 565 62.0 4.84 HVO_1745 conserved hypothetical protein 11.45 1 2 2 2 2.337E7 0.00 11.45 2 2 227 24.8 4.22 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 11.41 1 4 4 20 6.955E7 21.18 11.41 4 10 1036.42 11.41 4 10 403 41.1 4.73 HVO_A0547 DUF1028 family protein 11.41 1 3 3 7 2.761E7 2.73 11.41 3 4 320.58 11.41 3 3 333 35.2 4.16 HVO_0561 50S ribosomal protein L15e 11.22 1 2 2 6 5.619E7 6.66 11.22 2 3 487.67 11.22 2 3 196 22.5 11.15 HVO_0322 MinD/ParA domain protein 11.19 1 4 4 18 1.633E8 17.93 10.15 3 9 1275.01 11.19 4 9 581 58.8 3.70 HVO_B0143 receiver/sensor box histidine kinase 11.06 1 5 5 16 5.274E7 19.23 11.06 5 8 1151.70 11.06 5 8 597 66.0 4.41 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 10.99 1 0 6 29 3.787E8 30.53 10.99 6 15 1651.00 10.99 6 14 473 51.2 5.05 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 10.97 1 3 3 10 1.977E7 12.93 10.97 3 5 852.98 10.97 3 5 383 41.9 4.21 HVO_1340 "probable glycosyltransferase, type 1" 10.93 1 4 4 14 1.222E8 8.73 10.93 4 7 716.15 10.93 4 7 375 41.0 4.42 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 10.81 1 4 5 14 4.655E7 9.71 10.81 5 7 811.45 8.78 4 7 444 47.1 4.77 HVO_1323 "shikimate kinase, archaeal-type" 10.73 1 3 3 13 9.522E7 12.18 9.00 2 6 1034.66 10.73 3 7 289 29.5 4.30 HVO_2131 "fructose-1,6-bisphosphatase" 10.73 1 2 2 6 1.425E7 7.38 10.73 2 3 412.54 10.73 2 3 289 31.3 4.48 21961227 Keratin 6B [Homo sapiens] 10.64 1 0 8 46 2.920E8 41.89 10.64 8 23 2835.56 10.64 8 23 564 60.0 8.00 HVO_0811 tyrosine decarboxylase 10.64 1 2 2 4 9.197E6 0.00 10.64 2 2 66.45 10.64 2 2 357 38.5 4.97 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 10.62 1 6 6 19 3.086E7 4.02 10.62 6 10 723.82 9.08 5 9 584 63.3 4.79 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 10.56 1 3 3 14 4.647E7 14.25 10.56 3 7 973.31 10.56 3 7 360 39.5 4.31 HVO_0326 CTP-dependent riboflavin kinase 10.55 1 2 2 6 5.252E7 8.30 10.55 2 3 535.39 10.55 2 3 237 25.9 4.55 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 10.53 1 3 3 8 2.051E7 10.94 10.53 3 4 538.92 10.53 3 4 323 34.9 5.24 HVO_B0324 conserved hypothetical protein 10.47 1 4 4 9 3.303E7 4.06 8.46 3 4 295.84 10.47 4 5 449 48.0 4.58 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 10.46 1 0 8 41 2.534E8 32.50 10.46 8 21 2269.24 10.46 8 20 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 10.46 1 0 8 41 2.534E8 32.50 10.46 8 21 2269.24 10.46 8 20 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 10.46 1 0 8 41 2.534E8 32.50 10.46 8 21 2269.24 10.46 8 20 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 10.46 1 0 8 41 2.534E8 32.50 10.46 8 21 2269.24 10.46 8 20 564 60.0 7.72 HVO_A0586 sugar nucleotidyltransferase 10.46 1 3 3 12 3.973E7 14.06 10.46 3 6 831.12 10.46 3 6 411 43.7 4.69 HVO_0968 NADH dehydrogenase-like complex subunit CD 10.46 1 1 6 24 2.153E8 20.77 10.46 6 12 1409.20 10.46 6 12 564 63.3 4.60 HVO_2158 malic enzyme (NADP) 10.39 1 1 5 21 1.290E8 10.01 10.39 5 11 944.79 10.39 5 10 751 81.4 4.55 HVO_1452 citryl-CoA lyase (citrate lyase beta subunit / ATP citrate synthase beta subunit) 10.39 1 2 2 2 1.561E7 290.81 10.39 2 2 279 29.0 4.54 HVO_B0233 alpha-L-arabinofuranosidase 10.37 1 4 4 13 2.490E7 14.02 10.37 4 7 724.11 10.37 4 6 511 57.5 4.39 HVO_1723 DNA repair helicase Rad25 10.36 1 7 7 26 4.134E7 21.50 10.36 7 13 1674.49 10.36 7 13 695 76.8 4.69 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 10.36 1 3 3 12 3.104E7 14.68 10.36 3 6 651.16 10.36 3 6 386 41.3 4.46 HVO_1139 squalene synthase 10.34 1 2 2 5 7.509E7 5.92 10.34 2 3 353.80 10.34 2 2 358 39.7 4.54 HVO_2793 conserved hypothetical protein 10.32 1 2 2 8 4.561E7 10.38 10.32 2 4 441.03 10.32 2 4 252 27.1 4.46 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 10.24 1 3 3 4 2.071E7 272.03 10.24 3 4 381 40.5 4.51 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 10.23 1 4 4 26 1.895E8 19.74 10.23 4 13 1346.51 10.23 4 13 430 44.2 4.37 HVO_A0267 D-galactonate dehydratase 10.18 1 3 3 4 3.850E6 0.00 8.09 2 2 145.62 8.36 2 2 383 42.5 4.86 HVO_2350 YyaL family protein 10.14 1 4 4 16 7.092E7 8.36 10.14 4 8 749.53 10.14 4 8 552 58.8 4.59 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 10.13 1 5 5 17 1.531E8 16.34 10.13 5 9 1254.08 6.70 4 8 612 67.3 4.16 HVO_1059 conserved hypothetical protein 10.00 1 2 2 3 1.138E7 0.00 10.00 2 3 180 20.6 4.97 HVO_1685 conserved hypothetical protein 9.96 1 5 5 16 5.265E7 5.64 9.96 5 8 757.22 9.96 5 8 492 54.5 5.74 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 9.90 1 7 7 30 6.047E7 22.46 9.90 7 15 1950.15 9.90 7 15 838 89.1 4.65 HVO_C0043 conserved hypothetical protein 9.83 1 6 6 13 4.201E7 4.52 6.66 4 6 668.09 9.83 6 7 661 73.8 4.75 HVO_0110 sensor box histidine kinase 9.77 1 2 2 2 5.410E8 0.00 9.77 2 2 348 37.7 4.35 HVO_0019 probable S-adenosylmethionine-dependent methyltransferase (homolog to 24-sterol C-methyltransferase) 9.73 1 2 2 6 2.083E7 6.00 9.73 2 3 358.43 9.73 2 3 226 25.6 4.64 HVO_2640 conserved hypothetical protein 9.71 1 2 2 3 1.819E7 4.70 9.71 2 3 309 33.9 4.56 HVO_1885 TrkA domain protein 9.68 1 2 2 4 4.180E6 0.00 9.68 2 2 92.42 9.68 2 2 217 23.4 4.75 HVO_0476 conserved hypothetical protein 9.63 1 2 2 8 1.584E7 11.63 9.63 2 4 661.19 9.63 2 4 218 23.8 4.60 HVO_2605 MiaB-like tRNA modifying enzyme 9.56 1 3 3 12 2.632E7 13.98 9.56 3 6 649.55 9.56 3 6 429 47.4 5.03 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 9.53 1 3 3 8 1.250E8 4.04 7.72 2 4 283.86 9.53 3 4 661 71.0 4.35 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 9.51 1 4 4 12 2.382E7 2.38 9.51 4 6 501.25 9.51 4 6 410 46.0 4.89 HVO_1140 acyl-CoA dehydrogenase 9.47 1 3 3 8 2.128E7 5.11 9.47 3 4 446.32 9.47 3 4 380 41.2 4.55 HVO_A0350 conserved hypothetical protein 9.39 1 2 2 4 3.413E7 4.14 9.39 2 2 179.81 9.39 2 2 213 23.8 9.64 HVO_0145 replication factor C small subunit 9.38 1 2 2 2 1.999E7 2.22 9.38 2 2 341 37.8 4.93 HVO_1437 conserved hypothetical protein 9.36 1 2 2 6 1.313E7 4.08 9.36 2 3 319.30 9.36 2 3 203 22.3 4.94 HVO_2573 probable methenyltetrahydrofolate cyclohydrolase 9.35 1 2 2 6 5.909E7 8.41 9.35 2 3 449.49 9.35 2 3 310 32.7 3.92 HVO_A0093 IclR family transcription regulator 9.35 1 3 3 8 1.154E7 3.38 9.35 3 4 309.12 9.35 3 4 246 27.5 5.15 HVO_C0067 FAD-dependent oxidoreductase 9.34 1 2 2 11 6.380E7 10.68 9.34 2 6 523.74 9.34 2 5 396 42.7 4.30 HVO_A0401 Fido domain protein 9.33 1 2 2 3 4.457E6 5.66 9.33 2 3 386 43.5 4.72 HVO_B0060 precorrin-4 C11-methyltransferase 9.32 1 2 2 6 4.851E7 3.43 9.32 2 3 234.96 9.32 2 3 279 29.7 4.22 HVO_1055 TrkA domain protein 9.29 1 2 2 6 1.650E7 0.00 9.29 2 3 218.93 9.29 2 3 226 24.4 4.39 HVO_1413 probable NADH dehydrogenase 9.28 1 3 3 7 4.779E7 6.54 9.28 3 3 441.96 9.28 3 4 377 39.7 4.67 HVO_0558 SAMP-activating enzyme E1 9.26 1 2 2 6 3.835E7 5.12 9.26 2 3 494.25 9.26 2 3 270 28.7 4.35 HVO_A0257 Orc1-type DNA replication protein 9.18 1 3 3 14 1.527E7 10.59 9.18 3 7 755.10 9.18 3 7 425 48.0 4.94 HVO_3000 DNA ligase (NAD) 9.16 1 6 6 15 2.916E8 10.00 9.16 6 8 608.10 7.58 5 7 699 75.8 4.50 HVO_1937 "probable 5,10-methylenetetrahydrofolate reductase" 9.15 1 2 2 6 1.949E7 1.64 9.15 2 3 204.73 9.15 2 3 328 34.5 4.63 HVO_0069 sulfatase 9.13 1 4 4 9 2.260E7 7.17 7.57 3 4 523.38 9.13 4 5 515 57.4 4.35 HVO_A0328 2-keto-3-deoxygluconate kinase 9.12 1 1 2 6 1.809E8 4.23 9.12 2 3 339.09 9.12 2 3 318 34.0 4.60 HVO_0572 lipoate-protein ligase 9.09 1 2 2 9 1.737E7 8.97 9.09 2 5 616.70 9.09 2 4 275 30.5 4.84 HVO_1235 creatininase 9.09 1 2 2 5 3.527E7 336.46 9.09 2 5 264 29.2 4.84 HVO_1895 KEOPS complex subunit Kae1/Bud32 9.06 1 3 3 5 5.791E7 12.37 9.06 3 5 552 59.0 5.07 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 9.00 1 3 3 8 9.935E6 7.89 9.00 3 4 560.93 9.00 3 4 400 44.2 4.32 HVO_2955 DEAD/DEAH box helicase 8.99 1 5 5 11 3.678E7 5.79 8.99 5 7 320.24 4.88 3 4 779 85.8 4.94 4504919 keratin 8 [Homo sapiens] 8.90 1 1 6 32 1.654E8 18.18 8.90 6 16 1501.19 8.90 6 16 483 53.7 5.59 HVO_1710 alpha amylase 8.86 1 7 7 19 6.525E7 9.80 8.12 6 9 936.08 8.86 7 10 677 75.0 4.45 HVO_0073 single-stranded-DNA-specific exonuclease RecJ1 8.82 1 3 3 9 2.604E7 5.87 8.82 3 5 410.81 4.20 2 4 476 50.6 4.68 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 8.81 1 3 3 10 3.521E7 3.66 8.81 3 5 431.07 8.81 3 5 386 40.0 4.68 HVO_1584 GNAT family acetyltransferase 8.81 1 2 2 7 1.100E7 2.16 8.81 2 3 315.55 8.81 2 4 193 21.7 4.69 HVO_1313 probable S-adenosylmethionine-dependent methyltransferase 8.78 1 2 2 7 1.991E7 4.22 8.78 2 3 339.51 8.78 2 4 467 51.9 4.60 386849 keratin type II 8.70 1 0 5 17 2.195E8 18.12 8.70 5 9 1034.18 8.70 5 8 563 59.9 7.94 HVO_0305 electron transfer flavoprotein beta subunit 8.68 1 2 2 7 5.049E7 3.50 8.68 2 4 329.67 8.68 2 3 265 28.5 4.04 HVO_1746 DUF2800 family protein 8.67 1 2 2 4 3.017E7 1.90 8.67 2 2 48.03 8.67 2 2 323 36.5 4.37 HVO_1812 conserved hypothetical protein 8.53 1 3 3 12 3.743E7 10.26 8.53 3 6 831.67 8.53 3 6 375 40.5 4.50 HVO_B0038A D-xylonate dehydratase 8.25 1 0 3 20 2.976E8 19.29 8.25 3 10 1069.75 8.25 3 10 412 45.5 4.55 HVO_2860 conserved hypothetical protein 8.19 1 4 4 8 1.587E7 4.14 8.19 4 4 410.30 8.19 4 4 562 58.9 4.49 HVO_0469 AstE family protein 8.18 1 2 2 4 8.249E7 5.72 8.18 2 2 392.33 8.18 2 2 318 33.9 5.85 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 8.18 1 3 3 10 2.835E7 4.79 8.18 3 5 522.93 8.18 3 5 379 41.7 4.83 HVO_2248 conserved hypothetical protein 8.12 1 2 2 4 1.297E7 2.73 8.12 2 2 222.00 8.12 2 2 271 31.3 4.77 HVO_1704 homolog to arabinopyranose mutase 8.05 1 2 2 4 4.472E7 2.50 8.05 2 2 265.23 8.05 2 2 385 43.4 4.23 HVO_2923 proteasome alpha subunit 8.03 1 1 2 8 4.034E8 8.91 8.03 2 4 587.95 8.03 2 4 249 26.7 4.39 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 8.00 1 0 4 16 3.682E8 15.35 8.00 4 8 905.56 8.00 4 8 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 8.00 1 0 4 16 3.682E8 15.35 8.00 4 8 905.56 8.00 4 8 400 44.1 5.14 HVO_1537 Orc1-type DNA replication protein 8.00 1 2 2 4 1.690E7 0.00 8.00 2 2 154.54 8.00 2 2 400 42.4 5.52 HVO_0757 probable oxidoreductase (aldo-keto reductase family protein) 7.99 1 2 2 2 1.689E7 117.29 7.99 2 2 363 39.1 4.77 HVO_1117 HTH-10 family transcription regulator 7.98 1 2 2 3 8.167E6 199.90 7.98 2 3 213 23.3 4.56 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 7.92 1 2 2 8 5.815E7 7.30 7.92 2 4 587.18 7.92 2 4 442 46.9 4.58 HVO_2479 2-phospho-L-lactate transferase 7.88 1 2 2 5 2.303E7 4.30 7.88 2 2 325.65 7.88 2 3 330 34.7 4.32 HVO_B0101 IclR family transcription regulator 7.78 1 2 2 4 2.970E7 4.44 7.78 2 2 130.28 7.78 2 2 257 28.6 5.02 HVO_0065 DNA-directed DNA polymerase D large subunit 7.65 1 5 5 10 5.492E7 0.00 5.66 4 4 241.41 6.91 4 6 1202 133.9 4.60 HVO_2321 bacterial-type DNA primase DnaG 7.63 1 2 2 3 2.225E7 4.92 7.63 2 3 472 49.4 4.36 HVO_A0150 TrmB family transcription regulator 7.63 1 3 3 8 9.355E7 0.00 7.63 3 4 366.60 7.63 3 4 354 39.0 4.63 HVO_2812 AstE family protein 7.62 1 2 2 4 2.612E7 2.73 7.62 2 2 153.49 7.62 2 2 341 37.3 5.14 HVO_0990 DHH family phosphoesterase 7.61 1 3 3 5 2.155E7 0.00 7.61 3 3 86.07 4.73 2 2 486 51.9 4.59 HVO_1380 methylmalonyl-CoA mutase subunit A 7.53 1 3 3 10 3.471E7 7.28 7.53 3 5 482.11 7.53 3 5 558 61.9 4.41 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 7.52 1 3 3 14 3.494E7 3.25 7.52 3 7 508.95 7.52 3 7 439 47.2 4.59 HVO_0197 PurE family protein 7.51 1 2 2 4 1.351E7 2.79 7.51 2 2 185.18 7.51 2 2 253 25.5 4.42 HVO_0741 DNA-directed DNA polymerase X 7.39 1 3 3 10 2.102E7 7.50 7.39 3 5 671.50 7.39 3 5 582 62.6 4.44 HVO_A0254 DUF234 domain protein 7.38 1 4 4 11 2.648E7 7.25 7.38 4 5 541.57 7.38 4 6 461 52.7 4.78 HVO_1169 "probable glycosyltransferase, type 1" 7.34 1 2 2 6 1.083E7 1.87 7.34 2 3 230.62 7.34 2 3 368 40.8 4.73 HVO_2421 probable DNA-binding protein 7.23 1 2 2 6 3.362E7 5.98 7.23 2 3 325.12 7.23 2 3 235 25.8 4.89 HVO_1615 conserved hypothetical protein 7.17 1 2 2 6 1.594E7 1.71 7.17 2 3 260.69 7.17 2 3 251 28.4 4.59 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 7.02 1 0 4 16 3.682E8 15.35 7.02 4 8 905.56 7.02 4 8 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 7.02 1 0 4 16 3.682E8 15.35 7.02 4 8 905.56 7.02 4 8 456 49.2 4.77 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 8 4.122E8 6.25 6.94 3 4 514.45 6.94 3 4 389 40.8 4.89 31074633 keratin 6L [Homo sapiens] 6.92 1 0 4 14 1.973E8 13.40 6.92 4 7 919.17 6.92 4 7 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 6.92 1 0 4 14 1.973E8 13.40 6.92 4 7 919.17 6.92 4 7 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 6.92 1 0 4 14 1.973E8 13.40 6.92 4 7 919.17 6.92 4 7 535 57.7 7.20 HVO_1309 peptidase M24 family protein 6.91 1 3 3 12 1.338E8 3.61 6.91 3 6 486.06 6.91 3 6 391 42.1 4.36 HVO_B0345 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 6.88 1 2 2 4 5.499E7 1.97 6.88 2 2 134.68 6.88 2 2 378 41.2 4.84 HVO_0568 TrmB family transcription regulator 6.88 1 3 3 8 1.269E7 1.97 6.88 3 4 286.24 6.88 3 4 349 38.3 4.56 HVO_1735 conserved hypothetical protein 6.82 1 4 4 11 1.376E7 7.29 6.82 4 5 626.28 6.82 4 6 660 75.7 4.50 HVO_2503 kynureninase 6.82 1 3 3 8 3.808E7 4.48 6.82 3 4 382.83 6.82 3 4 425 46.0 4.54 31074631 keratin 1b [Homo sapiens] 6.75 1 1 4 23 3.952E8 19.37 6.75 4 12 1456.04 4.67 3 11 578 61.8 5.97 HVO_2873 flap endonuclease Fen1 6.75 1 2 2 8 5.681E7 11.67 6.75 2 4 793.96 6.75 2 4 326 36.4 4.40 HVO_1357 receiver/bat box HTH-10 family transcription regulator 6.70 1 3 3 7 2.830E7 4.85 6.70 3 4 329.46 5.67 2 3 582 62.7 4.40 HVO_C0057 Orc1-type DNA replication protein 6.70 1 3 3 6 2.432E7 6.66 6.70 3 3 341.05 6.70 3 3 418 46.3 5.02 HVO_1419 HTH-10 family transcription regulator 6.67 1 2 2 6 4.155E7 1.63 6.67 2 3 236.59 6.67 2 3 225 25.2 4.77 HVO_A0583 IclR family transcription regulator 6.64 1 2 2 4 1.835E7 0.00 6.64 2 2 125.56 6.64 2 2 256 27.9 5.07 HVO_2932 GTP-binding protein 6.57 1 2 2 8 5.383E7 2.26 6.57 2 4 339.40 6.57 2 4 396 43.5 4.51 HVO_0003 DNA-directed DNA polymerase D exonuclease subunit DP1 6.38 1 3 3 6 1.188E7 5.02 6.38 3 3 237.47 6.38 3 3 533 57.8 4.77 HVO_1008 GFO family oxidoreductase 6.33 1 2 2 8 2.845E7 6.38 6.33 2 4 516.46 6.33 2 4 332 36.0 4.72 HVO_1135 conserved hypothetical protein 6.31 1 2 2 2 8.486E6 2.12 6.31 2 2 301 32.8 5.15 HVO_A0562 urocanate hydratase 6.29 1 3 3 8 1.517E7 5.15 6.29 3 4 371.14 6.29 3 4 620 67.9 4.70 HVO_1681 DNA N-glycosylase 6.25 1 2 2 7 1.391E7 4.72 6.25 2 3 495.46 6.25 2 4 304 34.2 4.63 HVO_2809 succinate dehydrogenase subunit B (iron-sulfur protein) 6.14 1 2 2 6 1.732E7 0.00 6.14 2 3 219.44 6.14 2 3 293 33.9 5.27 HVO_1650 polyphosphate kinase 6.13 1 5 5 16 1.483E7 10.57 5.29 4 7 795.90 6.13 5 9 832 93.6 4.65 HVO_0058 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 6.08 1 3 3 4 5.235E6 0.00 4.95 2 2 147.25 2.70 2 2 444 50.2 4.84 HVO_1676 transcription initiation factor TFB 6.02 1 0 2 8 7.821E7 6.70 6.02 2 4 453.38 6.02 2 4 332 37.3 5.49 HVO_2911 deoxyribodipyrimidine photolyase 5.99 1 2 2 2 1.231E7 1.63 5.99 2 2 484 54.5 4.79 HVO_0464 threonine ammonia-lyase 5.96 1 2 2 5 1.661E7 2.88 5.96 2 3 185.29 5.96 2 2 403 43.7 4.72 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 5.95 1 2 2 8 6.801E7 4.48 5.95 2 4 351.02 5.95 2 4 353 36.7 4.65 HVO_2510 GNAT family acetyltransferase 5.92 1 2 2 3 3.862E7 231.81 5.92 2 3 304 33.7 4.49 HVO_A0342 IclR family transcription regulator 5.90 1 2 2 6 7.235E6 3.79 5.90 2 3 286.19 5.90 2 3 271 30.6 5.19 HVO_2187 CHP01210 family protein 5.83 1 2 2 4 1.427E7 2.21 5.83 2 2 239.37 5.83 2 2 360 40.0 4.58 HVO_1838 DUF262/DUF1524 domain protein (nonfunctional) 5.83 1 2 2 2 4.693E7 143.36 5.83 2 2 566 66.1 5.20 HVO_0425 "homolog to catechol-2,3-dioxygenase" 5.75 1 2 2 4 9.397E7 0.00 5.75 2 2 84.68 5.75 2 2 313 33.4 4.68 HVO_2263 conserved hypothetical protein 5.74 1 5 5 15 3.983E7 9.57 5.74 5 7 680.31 5.74 5 8 801 89.5 5.54 HVO_2071 conserved hypothetical protein 5.46 1 3 3 10 2.963E7 9.99 5.46 3 5 685.66 5.46 3 5 549 58.4 4.72 HVO_1052 transcription initiation factor TFB 5.42 1 0 2 8 1.051E8 6.50 5.42 2 4 478.87 5.42 2 4 332 37.3 5.25 31559823 keratin 25D [Homo sapiens] 5.39 1 0 3 15 2.517E8 15.94 5.39 3 8 869.51 5.39 3 7 464 50.6 5.47 HVO_2035 TrmB family transcription regulator 5.38 1 2 2 2 5.304E6 2.26 5.38 2 2 372 40.9 5.07 HVO_0029 UvrABC system protein B 5.30 1 3 3 8 3.386E7 6.88 5.30 3 4 385.29 5.30 3 4 698 79.0 4.45 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 5.28 1 2 2 9 1.335E8 9.50 5.28 2 5 556.25 5.28 2 4 398 43.4 4.37 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 5.15 1 2 2 7 4.122E7 3.34 5.15 2 3 322.81 5.15 2 4 388 41.9 4.35 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 5.04 1 2 2 6 2.671E7 1.76 5.04 2 3 211.72 5.04 2 3 337 35.9 4.39 HVO_1668 gamma-glutamylcysteine synthetase 5.03 1 2 2 4 7.014E6 1.96 5.03 2 2 129.60 5.03 2 2 358 39.9 4.72 HVO_0477 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 5.02 1 2 2 6 1.688E8 3.42 5.02 2 3 315.86 5.02 2 3 319 33.4 4.18 HVO_0687 M20 family amidohydrolase 4.95 1 2 2 8 2.631E7 5.85 4.95 2 4 652.16 4.95 2 4 444 47.5 4.58 4504911 keratin 13 isoform b [Homo sapiens] 4.76 1 0 2 8 1.100E8 10.67 4.76 2 4 521.22 4.76 2 4 420 45.8 4.88 HVO_0522 HdaI-type histone deacetylase 4.75 1 2 2 2 6.279E6 1.62 4.75 2 2 337 36.3 4.45 HVO_A0158 acyl-CoA synthetase 4.62 1 0 3 11 6.126E7 6.07 4.62 3 5 588.51 4.62 3 6 650 71.2 4.63 109255249 keratin 4 [Homo sapiens] 4.55 1 0 3 8 1.135E8 6.40 4.55 3 4 432.23 4.55 3 4 594 63.9 8.25 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 4.55 1 3 3 7 3.235E7 6.34 4.55 3 4 302.83 2.33 2 3 858 93.9 4.69 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 4.37 1 0 2 8 1.100E8 10.67 4.37 2 4 521.22 4.37 2 4 458 49.6 4.96 HVO_B0052 PQQ repeat protein 4.37 1 2 2 6 1.723E7 5.99 4.37 2 3 318.61 4.37 2 3 412 44.1 5.48 31559829 keratin 25A [Homo sapiens] 4.00 1 0 2 11 1.170E8 12.47 4.00 2 6 672.00 4.00 2 5 450 49.3 5.08 31559819 keratin 25C [Homo sapiens] 3.92 1 0 2 11 1.170E8 12.47 3.92 2 6 672.00 3.92 2 5 459 49.8 5.14 HVO_0418 homolog to haloviral protein 3.82 1 2 2 4 5.031E6 1.73 3.82 2 2 142.28 3.82 2 2 498 57.6 5.22 HVO_1916 Kef-type transport system (probable substrate potassium) 3.78 1 3 3 6 3.771E7 0.00 3.78 3 3 127.03 3.78 3 3 635 66.2 4.63 18031720 keratin protein K6irs [Homo sapiens] 3.73 1 0 2 8 1.052E8 7.89 3.73 2 4 340.12 3.73 2 4 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 3.72 1 0 2 8 1.052E8 7.89 3.72 2 4 340.12 3.72 2 4 511 55.8 6.89 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 3.66 1 2 2 8 2.474E7 2.00 3.66 2 4 355.35 3.66 2 4 437 47.1 4.72 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 8 1.052E8 7.89 3.63 2 4 340.12 3.63 2 4 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.59 1 0 2 8 1.052E8 7.89 3.59 2 4 340.12 3.59 2 4 529 57.8 7.71 28173564 keratin 6 irs3 [Homo sapiens] 3.52 1 0 2 8 1.052E8 7.89 3.52 2 4 340.12 3.52 2 4 540 58.9 7.23 HVO_1940 DNA mismatch repair protein MutS 3.37 1 2 2 2 7.451E6 169.60 3.37 2 2 921 99.4 4.42 HVO_0311 A-type ATP synthase subunit I 3.27 1 2 2 6 4.135E7 4.99 3.27 2 3 431.00 3.27 2 3 733 79.5 4.41 HVO_0283 archaea-specific helicase AshA 2.92 1 2 2 3 2.527E7 103.49 2.92 2 3 684 76.3 5.53 HVO_2736 tRNA(Met) cytidine acetyltransferase 2.79 1 2 2 6 1.687E7 0.00 2.79 2 3 203.27 2.79 2 3 754 81.2 4.96 HVO_2175 SMC-like protein Sph3 2.75 1 2 2 4 1.581E7 1.73 2.75 2 2 174.64 2.75 2 2 654 74.2 4.54 66774007 "Keratin, type II cytoskeletal 1b" 2.60 1 0 2 14 1.305E8 5.91 2.60 2 7 646.50 2.60 2 7 576 61.7 5.85 HVO_2767 ATP-dependent DNA helicase Dna2 2.49 1 2 2 3 7.160E6 269.84 2.49 2 3 884 97.5 4.86 HVO_0753 conserved hypothetical protein 2.26 1 2 2 3 2.055E7 0.00 2.26 2 3 1018 106.4 4.86