Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0356 translation elongation factor aEF-2 78.95 1 44 44 569 4.785E9 577.33 78.95 44 286 35449.01 78.95 44 283 727 80.4 4.73 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 72.29 1 18 18 198 1.921E9 213.50 70.29 17 98 13633.47 72.29 18 100 350 37.6 4.54 HVO_0359 translation elongation factor aEF-1 alpha subunit 72.21 1 21 25 753 1.143E10 737.34 72.21 24 362 54070.62 72.21 25 391 421 45.7 4.73 HVO_0880 conserved hypothetical protein 69.71 1 27 27 213 7.568E8 195.80 69.06 26 106 12931.81 69.71 27 107 307 36.3 4.74 HVO_2862 serine hydroxymethyltransferase 67.23 1 17 17 183 1.299E9 192.18 65.06 16 91 12346.57 67.23 17 92 415 44.3 4.53 HVO_1273 inosine-5'-monophosphate dehydrogenase 66.67 1 21 21 176 9.527E8 188.67 64.06 20 87 11039.98 66.67 21 89 498 53.3 4.55 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 66.40 1 17 17 145 1.812E9 107.08 66.40 17 73 8006.09 66.40 17 72 381 41.0 4.23 HVO_1921 serine--tRNA ligase 66.09 1 26 26 106 4.638E8 94.03 66.09 25 52 6534.58 58.26 25 54 460 52.0 4.46 HVO_0602 3-dehydroquinate dehydratase 63.16 1 11 12 35 5.733E7 22.52 53.04 11 17 1464.22 57.09 11 18 247 27.3 4.51 HVO_2900 fumarate hydratase 63.11 1 17 17 106 9.988E8 114.22 63.11 17 53 6443.32 63.11 17 53 469 50.1 4.78 HVO_1454 aspartate carbamoyltransferase catalytic subunit 62.17 1 13 13 57 1.140E8 67.72 62.17 13 29 4048.60 62.17 13 28 304 33.7 4.92 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 61.21 1 14 14 56 3.515E8 59.13 61.21 14 29 3790.87 55.16 13 27 281 30.6 4.59 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 60.90 1 12 12 133 1.753E9 107.44 60.90 12 66 7707.01 60.90 12 67 312 34.5 4.98 HVO_0859 FeS assembly ATPase SufC 60.47 1 15 15 99 1.033E9 81.90 58.47 14 50 6102.77 60.47 15 49 301 33.4 4.35 HVO_2724 beta-lactamase domain protein 60.44 1 19 20 138 1.224E9 127.60 60.44 20 70 7209.56 55.78 18 68 450 50.1 5.40 HVO_0850 proteasome-activating nucleotidase 60.25 1 17 17 70 3.147E8 71.25 53.09 15 34 5095.00 60.25 17 36 405 45.6 4.60 HVO_0239 glutamine synthetase 60.09 1 19 19 119 1.213E9 111.55 48.90 17 58 7751.17 60.09 19 61 456 50.5 4.56 HVO_2588 isocitrate dehydrogenase (NADP) 59.90 1 21 21 171 1.883E9 180.18 56.80 20 87 11148.75 52.51 20 84 419 45.8 4.59 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 59.48 1 14 14 57 2.563E8 56.33 59.48 14 28 4162.27 59.48 14 29 343 38.4 4.94 HVO_1507 acetolactate synthase small subunit 58.72 1 8 8 28 7.313E7 10.57 58.72 8 14 1247.97 58.72 8 14 218 23.7 4.94 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 58.59 1 16 16 132 1.258E9 146.15 58.59 16 64 10525.14 58.59 16 68 384 41.4 4.41 HVO_2889 RecJ domain protein 58.16 1 28 29 194 1.202E9 183.45 58.16 29 95 12592.87 58.16 29 99 729 79.1 4.37 HVO_0433 F420H2:NADP oxidoreductase 57.21 1 7 7 20 1.370E8 19.63 57.21 7 10 1230.54 57.21 7 10 222 23.3 4.72 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 56.93 1 23 23 95 7.929E8 89.09 52.70 21 47 6025.22 50.51 22 48 592 66.6 4.61 HVO_0778 thermosome subunit 3 56.68 1 21 23 134 5.737E8 146.86 54.01 21 67 9507.13 56.68 23 67 524 55.2 4.59 HVO_0167 adenosylhomocysteinase 56.54 1 16 16 59 2.368E8 63.94 52.34 15 28 3954.42 56.54 16 31 428 46.6 4.39 HVO_2191 formyltetrahydrofolate deformylase 55.66 1 15 15 65 4.596E8 49.77 55.66 15 33 3601.67 55.66 15 32 327 36.2 4.63 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 55.41 1 9 9 29 5.119E7 19.48 55.41 9 14 1668.15 55.41 9 15 231 25.0 4.25 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 54.88 1 13 13 53 6.514E8 30.32 50.17 12 26 2640.40 54.88 13 27 297 31.3 4.36 HVO_0348 DNA-directed RNA polymerase subunit B' 54.84 1 25 25 126 5.837E8 130.44 54.84 25 63 8144.47 54.84 25 63 609 67.7 4.92 HVO_1145 30S ribosomal protein S1e 54.55 1 9 9 41 2.912E8 40.08 54.55 9 20 2974.71 54.55 9 21 220 24.8 4.86 HVO_0677 aspartate--tRNA ligase 54.15 1 18 18 142 1.773E9 142.90 53.00 17 70 8513.35 54.15 18 72 434 48.7 4.50 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 54.08 1 11 11 48 2.781E8 40.58 54.08 11 24 2717.31 54.08 11 24 355 38.2 4.68 HVO_0104 DNA repair and recombination protein RadA 53.94 1 13 13 85 6.627E8 60.87 46.94 11 41 6119.58 53.94 13 44 343 37.3 4.64 HVO_0055 CBS domain protein 53.87 1 11 11 74 6.005E8 80.88 53.87 11 38 5765.69 46.48 10 36 284 30.8 4.27 HVO_2413 translation elongation factor aEF-1 alpha subunit 53.81 1 12 16 94 1.212E9 71.44 53.81 16 45 4817.49 53.81 16 49 420 45.6 4.75 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 53.54 1 8 8 37 1.376E8 34.91 53.54 8 19 2491.48 53.54 8 18 254 26.9 4.42 HVO_2968 phosphoglycerate dehydrogenase 52.76 1 18 18 145 1.350E9 172.14 52.76 18 73 11340.08 52.76 18 72 525 55.3 4.36 HVO_0317 A-type ATP synthase subunit B 52.35 1 16 17 124 1.403E9 156.91 52.35 17 62 9776.22 52.35 17 62 468 51.9 4.25 HVO_0347 DNA-directed RNA polymerase subunit B'' 52.02 1 27 27 161 4.812E8 95.53 52.02 27 81 8850.59 50.86 25 80 521 58.9 5.00 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 51.75 1 9 9 29 1.767E8 23.41 51.75 9 14 1652.29 51.75 9 15 286 31.2 4.54 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 51.66 1 12 12 44 1.271E8 45.27 51.66 12 22 2475.40 51.66 12 22 422 43.6 4.72 HVO_0861 SufB domain protein 51.49 1 14 14 103 1.012E9 111.84 48.01 13 50 7872.77 51.49 14 53 402 44.7 4.23 HVO_0025 thiosulfate sulfurtransferase 51.40 1 12 12 87 2.579E9 55.16 48.95 11 45 4843.01 51.40 12 42 286 32.1 4.28 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 51.33 1 12 12 65 6.587E8 41.35 46.49 11 31 3215.68 51.33 12 34 413 45.8 4.45 HVO_2059 NAD-dependent epimerase/dehydratase 51.29 1 10 10 33 2.467E8 20.30 41.94 8 16 1878.37 51.29 10 17 310 34.1 4.40 HVO_0329 branched-chain amino acid aminotransferase 51.28 1 13 13 71 5.083E8 69.42 51.28 13 37 3934.48 51.28 13 34 312 35.0 4.58 HVO_1506 ketol-acid reductoisomerase 51.15 1 9 9 31 1.770E8 30.66 40.80 8 15 2088.73 42.53 8 16 348 37.9 4.34 HVO_0792 3-dehydroquinate synthase type II 50.77 1 13 13 63 2.664E8 69.55 50.77 13 31 4427.04 50.77 13 32 392 43.1 4.44 HVO_2646 dihydroxy-acid dehydratase 50.68 1 17 17 85 6.970E8 79.10 50.68 17 43 5146.02 45.72 16 42 584 61.8 4.42 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 12 1.075E8 5.06 37.91 4 6 445.21 38.56 4 6 153 16.9 4.21 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 49.48 1 11 11 69 6.299E8 61.45 49.48 11 34 4265.12 49.48 11 35 287 31.0 4.73 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 48.79 1 9 9 69 7.432E8 80.00 43.25 7 32 6032.64 48.79 9 37 289 29.8 4.27 HVO_0133 thermosome subunit 1 48.39 1 18 20 117 8.086E8 124.04 41.79 18 57 9008.10 48.04 19 60 560 58.9 4.25 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 47.94 1 14 14 50 1.274E8 42.77 47.94 14 25 2782.56 47.94 14 25 340 38.8 4.58 HVO_1084 adenylosuccinate lyase 47.73 1 18 18 67 2.751E8 52.86 47.73 18 32 4168.51 47.73 17 35 463 50.8 4.70 HVO_0455 thermosome subunit 2 47.58 1 22 23 137 5.852E8 136.22 46.32 22 66 9249.85 47.58 23 71 557 59.3 4.37 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 47.19 1 12 12 43 2.003E8 42.88 47.19 12 22 2685.39 45.17 11 21 445 47.8 4.86 HVO_2552 30S ribosomal protein S4e 46.96 1 7 7 109 2.708E9 96.75 46.96 7 55 5881.29 46.96 7 54 247 26.6 4.58 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 46.79 1 6 6 40 5.919E8 38.61 32.14 5 19 3110.60 46.79 6 21 280 30.1 4.44 HVO_0581 "cell division protein FtsZ, type II" 46.75 1 12 12 53 4.935E8 62.07 46.75 12 27 3891.83 46.75 12 26 400 42.5 4.75 HVO_1132 adenylosuccinate synthase 46.73 1 22 22 150 1.415E9 116.03 43.57 20 72 9372.93 46.73 22 78 443 48.2 4.56 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 46.65 1 19 19 83 3.008E8 89.63 42.01 18 40 5220.48 46.65 19 43 626 67.6 4.65 HVO_0393 UvrABC system protein A 46.49 1 33 33 120 1.290E8 89.22 45.68 32 60 6310.65 44.46 32 60 983 108.6 4.82 HVO_2624 CTP synthase 46.45 1 18 18 84 3.092E8 65.27 42.62 15 39 4822.71 43.90 17 45 549 60.8 4.70 HVO_2969 threonine synthase 46.30 1 14 14 69 5.962E8 64.62 46.30 14 35 5207.62 46.30 14 34 419 44.4 4.49 HVO_0087 porphobilinogen synthase 46.18 1 9 9 30 8.893E7 24.17 38.53 8 15 1413.97 46.18 9 15 327 35.3 4.72 HVO_0869 glutamate synthase large subunit 46.13 1 52 53 277 6.972E8 246.36 44.94 51 137 17415.82 45.60 52 140 1511 163.8 4.70 HVO_1123 thioredoxin-disulfide reductase 46.13 1 10 10 37 2.578E8 21.73 24.36 7 14 2734.42 46.13 10 23 349 37.3 4.32 HVO_2774 enolase 46.12 1 11 12 53 6.180E8 28.59 44.36 11 27 2967.31 43.61 11 26 399 42.0 4.37 HVO_0240 Lrp/AsnC family transcription regulator 46.05 1 5 6 16 2.035E8 6.88 40.79 5 8 904.97 34.21 5 8 152 16.9 4.39 HVO_0806 pyruvate kinase 45.98 1 19 19 92 6.205E8 73.79 45.98 19 45 5518.40 45.98 19 47 585 62.0 4.54 HVO_2544 30S ribosomal protein S5 45.79 1 7 7 38 8.057E8 38.95 42.52 6 18 2545.37 45.79 7 20 214 23.3 9.29 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 45.51 1 20 20 96 4.267E8 97.91 45.35 19 46 6021.23 45.51 20 50 624 67.6 4.27 HVO_0999 DRTGG domain protein 45.50 1 12 12 50 2.299E8 50.70 45.50 12 25 3628.24 45.50 12 25 378 39.8 4.44 HVO_2336 pyridoxal biosynthesis lyase PdxS 45.36 1 10 10 40 9.336E7 34.38 41.72 9 19 2406.97 45.36 10 21 302 32.5 4.81 HVO_2981 uracil phosphoribosyltransferase 45.13 1 10 10 38 3.297E8 34.42 42.04 8 16 3019.16 45.13 10 22 226 24.5 4.49 HVO_1541 glycerol kinase 45.10 1 16 16 93 9.484E8 75.07 41.76 15 44 6480.66 45.10 16 49 510 56.7 4.50 HVO_1637 FKBP-type peptidylprolyl isomerase 44.77 1 11 12 62 1.159E9 67.99 36.27 11 30 4685.25 44.77 12 32 306 33.8 3.76 HVO_2487 aspartate-semialdehyde dehydrogenase 44.77 1 8 8 66 8.706E8 82.81 44.77 8 33 4010.05 44.77 8 33 344 36.6 4.41 HVO_0870 proline--tRNA ligase 44.67 1 14 14 69 3.292E8 54.44 42.21 13 35 4389.40 44.67 14 34 488 54.9 4.44 HVO_0324 arginine--tRNA ligase 44.46 1 21 21 93 3.864E8 91.12 41.91 19 44 6074.70 44.46 21 49 587 65.0 4.35 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 44.44 1 12 12 53 2.654E8 45.72 44.44 12 27 2888.45 36.67 11 26 360 39.6 4.39 HVO_A0207 CRISPR-associated protein Cas7 44.41 1 10 10 48 2.757E8 58.32 44.41 10 24 3677.79 44.41 10 24 340 38.2 4.54 HVO_0480 phosphoglycerate kinase 44.14 1 15 15 82 5.468E8 91.39 44.14 15 41 6778.97 44.14 15 41 401 43.6 4.37 HVO_1370 gamma-glutamyl phosphate reductase 44.14 1 15 15 56 2.068E8 41.95 44.14 15 28 3090.48 44.14 15 28 444 48.1 4.34 HVO_2204 "FtsZ family protein, type III" 44.05 1 13 15 72 5.694E8 77.66 44.05 15 36 5236.33 44.05 15 36 395 42.0 4.68 HVO_2384 CBS domain protein 43.95 1 14 14 77 6.379E8 61.37 42.63 13 40 4756.91 40.26 12 37 380 42.5 5.01 HVO_0860 SufB domain protein 43.91 1 17 17 112 1.263E9 106.79 40.76 16 53 7252.47 43.91 17 59 476 53.2 4.69 HVO_2621 phosphoenolpyruvate carboxylase 43.81 1 31 31 172 5.705E8 158.26 43.81 31 86 10756.86 43.70 30 86 897 102.3 4.64 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 43.75 1 19 19 74 2.957E8 60.35 41.13 17 35 4665.00 43.75 19 39 496 55.0 4.53 HVO_0424 ABC-type transport system ATP-binding protein 43.71 1 19 19 75 1.841E8 72.55 43.71 19 38 4215.95 43.71 19 37 604 67.2 4.49 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 43.63 1 9 9 38 3.407E8 47.72 43.63 9 19 3483.23 43.63 9 19 259 28.0 4.50 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 43.61 1 12 12 52 4.327E8 37.84 38.69 11 24 3248.41 43.61 12 28 305 33.8 4.74 HVO_0212 homolog to lactoylglutathione lyase 43.55 1 3 3 12 1.074E8 15.21 43.55 3 6 770.26 43.55 3 6 124 13.5 4.13 HVO_1504 3-isopropylmalate dehydratase large subunit 43.13 1 17 18 123 7.037E8 123.10 43.13 18 62 8971.22 40.59 16 61 473 51.6 4.55 HVO_1684 threonine--tRNA ligase 43.08 1 24 24 115 5.121E8 103.35 43.08 24 58 7193.15 43.08 24 57 643 73.4 4.45 HVO_0046 putative glutamate--argW ligase 42.96 1 9 9 41 2.669E8 42.79 42.96 9 20 2690.96 35.74 8 21 291 31.9 4.87 HVO_2015 conserved hypothetical protein 42.90 1 10 10 112 2.726E9 109.52 42.90 10 56 7413.84 42.90 10 56 345 37.7 4.25 HVO_2783 30S ribosomal protein S4 42.86 1 9 9 48 4.406E8 51.37 42.86 9 24 3130.47 42.86 9 24 175 20.1 5.24 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 42.57 1 7 7 21 3.364E7 18.33 37.13 6 10 1332.51 42.57 7 11 202 22.2 5.11 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.48 1 9 9 38 1.951E8 48.30 42.48 9 19 3053.83 42.48 9 19 266 27.8 4.84 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 42.48 1 15 15 79 6.182E8 66.57 40.57 14 40 4737.40 42.48 15 39 525 56.4 4.40 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 42.47 1 20 20 236 3.318E9 235.69 41.20 19 117 16125.31 42.47 20 119 631 68.4 4.49 HVO_2558 30S ribosomal protein S3 42.43 1 10 10 90 1.504E9 102.78 38.16 9 43 7325.31 42.43 10 47 304 33.4 4.06 HVO_2188 phosphoribosylformylglycinamidine synthase 1 42.41 1 7 7 33 1.710E8 29.73 42.41 7 16 2127.77 42.41 7 17 224 23.9 4.36 HVO_0980 NADH dehydrogenase-like complex subunit CD 42.37 1 15 19 80 2.482E8 65.73 42.37 19 40 4858.60 37.52 18 40 557 63.4 4.53 HVO_0874 beta-lactamase domain protein 42.03 1 22 22 107 5.062E8 85.83 42.03 22 54 7216.33 42.03 22 53 640 71.9 5.14 HVO_2057 sugar nucleotidyltransferase 42.02 1 13 13 75 3.383E8 65.08 42.02 13 38 4492.86 39.78 12 37 357 37.8 4.44 HVO_1590 DnaK-type molecular chaperone Hsp70 41.76 1 23 23 122 8.796E8 118.21 41.76 23 61 8301.75 41.76 23 61 625 67.2 4.18 HVO_B0059 cobalt-precorrin 5A hydrolase 41.72 1 9 9 33 6.396E7 34.81 34.66 8 16 2121.60 41.72 9 17 326 34.5 4.51 HVO_0316 A-type ATP synthase subunit A 41.64 1 19 19 127 1.323E9 141.38 41.64 18 63 10041.06 41.64 19 64 586 64.5 4.25 HVO_0789 tryptophan synthase alpha subunit 41.52 1 7 7 35 1.367E8 35.18 41.52 7 17 1916.69 41.52 7 18 277 29.6 4.21 HVO_0449 prephenate dehydratase 41.42 1 8 8 35 2.086E8 44.14 41.42 8 18 2444.75 41.42 8 17 268 28.7 4.64 HVO_0203 replication factor C small subunit 41.28 1 12 12 61 1.492E8 51.69 41.28 12 31 3646.62 41.28 12 30 327 36.2 4.51 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 41.14 1 12 12 64 2.093E8 55.34 41.14 12 33 3796.35 41.14 12 31 457 48.4 4.35 HVO_0661 dCTP deaminase (dUMP-forming) 41.03 1 5 5 14 4.907E7 7.35 41.03 5 7 705.11 41.03 5 7 195 21.2 4.59 HVO_0024 thiosulfate sulfurtransferase 40.70 1 7 7 24 1.862E8 18.20 36.05 6 11 1243.24 40.70 7 13 258 28.4 4.30 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 40.40 1 13 13 60 2.583E8 55.90 40.40 13 29 3649.50 40.40 13 31 453 47.5 4.63 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 40.27 1 34 34 165 3.111E8 144.07 38.82 33 80 10287.95 40.27 34 85 1033 114.3 4.45 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 40.21 1 5 5 13 7.604E7 9.21 40.21 5 7 649.28 31.96 4 6 97 10.8 4.53 HVO_2961 dihydrolipoyl dehydrogenase 40.21 1 12 12 50 1.255E8 45.60 34.74 11 24 3107.35 40.21 12 26 475 49.9 4.41 HVO_0292 replication protein A 40.19 1 10 10 34 1.124E8 34.14 40.19 10 17 2515.35 40.19 10 17 311 34.6 4.31 HVO_1649 methionine adenosyltransferase 40.05 1 12 12 40 1.104E8 26.57 40.05 12 20 2337.50 40.05 12 20 402 43.5 4.45 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 29 2.543E8 32.52 40.00 4 15 1769.82 40.00 4 14 130 14.1 4.79 HVO_1502 3-isopropylmalate dehydrogenase 39.81 1 10 10 64 6.568E8 49.25 39.81 10 32 4198.32 39.81 10 32 324 33.7 4.23 HVO_1091 proteasome alpha subunit 39.68 1 9 10 45 5.245E8 55.28 39.68 10 23 3091.34 36.11 9 22 252 27.6 4.56 HVO_0118 50S ribosomal protein L20e 39.66 1 2 2 2 0.000E0 114.01 39.66 2 2 58 6.4 6.52 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 39.59 1 18 18 132 8.477E8 128.20 39.59 18 67 8923.60 39.59 18 65 586 64.0 4.49 HVO_1459 ThuA family protein 39.50 1 5 5 14 4.629E7 14.67 30.25 4 7 861.98 31.93 4 7 238 26.8 4.67 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 39.50 1 18 18 73 2.002E8 77.16 33.50 16 35 5169.36 39.50 18 38 600 65.3 4.68 HVO_0358 homoserine dehydrogenase 39.43 1 7 7 38 1.992E8 29.33 39.43 7 19 2166.60 39.43 7 19 317 32.4 4.44 HVO_A0206 CRISPR-associated protein Cas8b 39.33 1 23 23 76 2.000E8 65.12 37.80 22 39 4218.36 36.54 22 37 717 79.3 4.60 HVO_1082 homolog to orotate phosphoribosyltransferase 39.05 1 7 7 21 9.637E7 15.27 39.05 7 11 1088.74 35.71 6 10 210 22.3 4.42 HVO_0400 conserved hypothetical protein 38.89 1 3 3 11 2.792E7 10.35 38.89 3 5 849.39 38.89 3 6 126 13.9 4.68 HVO_0161 ATP phosphoribosyltransferase 38.79 1 9 9 39 1.857E8 36.27 36.65 8 19 2859.57 38.79 9 20 281 30.4 4.60 HVO_0743 probable phosphodiesterase 38.75 1 20 20 96 4.783E8 66.02 38.75 20 48 5614.45 37.42 19 48 449 50.5 4.56 HVO_0313 A-type ATP synthase subunit E 38.66 1 5 5 22 1.227E8 22.42 31.44 4 11 1091.30 33.51 4 11 194 22.0 4.31 HVO_A0205 CRISPR-associated endoribonuclease Cas6 38.60 1 9 9 38 1.484E8 44.96 38.60 9 20 2835.60 35.29 8 18 272 31.0 5.44 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 38.56 1 16 16 52 1.426E8 59.79 37.23 15 27 4041.97 34.89 15 25 599 65.3 4.51 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 38.51 1 12 12 53 2.804E8 60.45 38.51 12 26 3256.93 38.51 12 27 348 38.2 4.32 HVO_0519 replication protein A 38.30 1 15 15 70 1.945E8 57.10 38.30 15 35 4474.71 38.30 15 35 483 51.0 4.13 HVO_0809 methionine--tRNA ligase 38.11 1 20 20 89 2.517E8 78.47 38.11 20 45 5680.95 36.62 19 44 740 81.9 4.37 HVO_2013 "FtsZ family protein, type III" 38.07 1 7 7 22 1.283E8 19.29 31.47 6 10 1384.98 31.47 6 12 394 41.5 4.61 HVO_1332 conserved hypothetical protein 37.98 1 5 5 18 9.603E7 13.79 29.46 4 8 1329.42 37.98 5 10 129 14.9 4.16 HVO_0206 alanine--tRNA ligase 37.96 1 26 26 117 1.940E8 98.16 36.23 24 58 7091.23 37.96 26 59 922 102.4 4.54 HVO_2519 conserved hypothetical protein 37.96 1 10 10 49 2.584E8 46.79 33.25 9 23 3466.66 37.96 10 26 382 40.7 4.35 HVO_0350 DNA-directed RNA polymerase subunit A'' 37.71 1 16 16 69 5.488E8 68.97 32.22 15 33 4550.88 37.71 16 36 419 46.1 4.35 HVO_0349 DNA-directed RNA polymerase subunit A' 37.50 1 29 29 139 3.402E8 142.85 37.50 29 70 9706.98 36.99 28 69 976 108.8 4.81 HVO_1550 acyl-CoA thioester hydrolase 37.50 1 4 4 13 5.929E7 10.59 30.63 3 6 1096.40 37.50 4 7 160 17.6 4.55 HVO_1172 NAD-dependent epimerase/dehydratase 37.46 1 9 9 41 3.393E8 31.12 34.92 8 19 3027.93 37.46 9 22 315 34.9 4.34 HVO_1284 GTP cyclohydrolase III 37.16 1 8 8 25 1.732E8 22.98 33.33 7 12 1518.38 37.16 8 13 261 28.9 4.70 HVO_1955 aconitate hydratase 37.16 1 20 20 171 2.216E9 184.74 35.93 19 86 12536.34 37.16 19 85 654 70.4 4.45 HVO_1031 thioredoxin-disulfide reductase 37.13 1 9 9 34 1.688E8 25.74 37.13 9 17 1841.93 37.13 9 17 342 37.4 4.46 HVO_2756 50S ribosomal protein L10 37.07 1 9 9 39 2.637E8 25.34 36.78 8 19 2176.96 37.07 9 20 348 36.9 3.99 HVO_0717 "cell division protein FtsZ, type I" 36.94 1 11 11 59 6.402E8 58.22 36.94 11 28 4638.68 36.94 11 31 379 39.8 4.40 HVO_2419 hydroxymethylglutaryl-CoA synthase 36.85 1 13 13 49 3.317E8 33.83 33.71 12 25 2269.53 36.85 13 24 445 50.1 4.64 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 36.84 1 5 5 41 4.068E8 45.24 36.84 5 20 3153.95 36.84 5 21 190 20.6 4.30 HVO_1338 replication protein A 36.77 1 13 13 38 1.130E8 33.07 36.77 13 20 2445.87 33.96 11 18 427 46.0 4.36 HVO_2773 30S ribosomal protein S2 36.54 1 6 6 49 1.061E9 48.66 36.54 6 25 3545.27 36.54 6 24 260 28.3 4.16 HVO_3007 malate dehydrogenase 36.51 1 12 12 149 1.722E9 117.42 33.55 11 73 7524.72 36.51 12 76 304 32.6 4.40 HVO_0041 ornithine carbamoyltransferase 36.45 1 7 7 32 1.596E8 21.33 33.11 6 15 1836.90 36.45 7 17 299 32.7 4.37 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 36.29 1 10 10 61 2.869E8 37.67 32.43 9 29 3572.40 36.29 10 32 259 29.9 4.36 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 36.08 1 4 4 26 4.303E8 25.06 25.26 3 10 2580.40 36.08 4 16 194 20.7 4.12 HVO_2726 glutamate--tRNA ligase 36.07 1 17 17 60 1.233E8 55.66 36.07 16 29 3456.14 36.07 17 31 585 65.2 4.58 HVO_1932 2-D-hydroxyacid dehydrogenase 36.04 1 8 8 24 4.897E7 20.20 36.04 8 12 1413.72 36.04 8 12 308 33.0 4.60 HVO_B0118 SMC-like protein Sph2 36.02 1 24 25 104 4.247E8 88.47 36.02 24 52 5608.41 35.25 24 52 644 73.8 4.41 HVO_0138 tyrosine--tRNA ligase 35.98 1 7 7 34 2.739E8 21.22 35.98 7 17 1747.25 35.98 7 17 328 36.1 4.34 HVO_2454 anthranilate synthase component I 35.88 1 15 15 52 1.890E8 49.97 35.88 15 26 3439.59 35.88 15 26 524 55.9 4.56 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 35.84 1 8 8 42 2.283E8 30.25 35.84 8 21 2598.01 35.84 8 21 226 25.5 4.25 40354192 keratin 10 [Homo sapiens] 35.45 1 0 19 64 2.831E8 64.43 35.45 19 33 3903.52 35.27 18 31 584 58.8 5.16 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 35.44 1 13 13 58 2.386E8 69.27 35.44 13 29 4390.94 35.44 13 29 474 53.4 4.59 HVO_0175 DNA polymerase sliding clamp 35.22 1 6 6 72 1.063E9 56.55 35.22 6 35 4327.70 35.22 6 37 247 26.7 4.39 HVO_1572 DNA gyrase subunit B 35.21 1 17 17 61 1.260E8 56.22 35.21 17 31 3830.89 32.08 16 30 639 71.2 4.83 HVO_1076 sugar nucleotidyltransferase 35.09 1 7 7 21 1.536E8 25.01 35.09 7 11 1860.34 23.60 5 10 322 35.8 4.20 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 34.91 1 0 19 64 2.831E8 64.43 34.91 19 33 3903.52 34.74 18 31 593 59.5 5.21 HVO_2813 RimK family protein 34.66 1 12 12 61 2.776E8 63.90 34.66 12 31 4172.44 34.66 12 30 453 49.0 4.73 HVO_1371 glutamate 5-kinase 34.55 1 8 8 27 1.906E8 23.52 34.55 8 13 1684.58 34.55 8 14 301 32.0 4.25 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 34.49 1 14 14 52 1.739E8 33.63 34.49 14 27 2399.44 29.72 12 25 461 50.7 4.73 HVO_0729 inorganic pyrophosphatase 34.46 1 7 7 34 4.123E8 29.65 34.46 7 17 1795.93 34.46 7 17 177 20.4 4.16 HVO_2740 nucleoside-diphosphate kinase 34.42 1 4 4 14 3.421E7 10.93 34.42 4 7 1112.18 34.42 4 7 154 17.5 4.50 HVO_1306 chorismate synthase 34.29 1 9 9 35 1.666E8 41.44 34.29 9 17 2104.79 34.29 9 18 385 41.9 4.83 HVO_0314 A-type ATP synthase subunit C 34.20 1 10 10 40 2.626E8 31.50 30.17 9 19 2598.61 34.20 10 21 348 38.7 4.50 HVO_1854 histidine--tRNA ligase 34.11 1 12 12 48 1.805E8 49.38 27.15 10 23 3306.65 34.11 12 25 431 47.1 4.37 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 33.96 1 10 10 38 7.688E7 27.46 33.96 10 19 2040.50 33.96 10 19 427 45.4 4.56 HVO_0100 NMD3 family protein 33.87 1 8 8 26 5.495E7 28.84 33.87 8 13 1725.16 33.87 8 13 375 41.6 4.46 HVO_2700 AAA-type ATPase (CDC48 subfamily) 33.82 1 24 25 82 1.136E8 63.54 33.82 25 41 4508.00 33.82 25 41 754 82.8 4.75 HVO_0008 aspartate kinase 33.67 1 7 7 47 5.801E8 43.97 33.67 7 23 2489.25 33.67 7 24 392 41.7 4.46 47132620 keratin 2a [Homo sapiens] 33.65 1 13 19 77 2.975E8 68.23 33.65 19 38 5056.83 33.65 19 39 639 65.4 8.00 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 33.46 1 11 11 43 2.219E8 35.12 33.46 11 22 2408.58 27.76 10 21 526 57.2 4.31 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 33.41 1 8 8 39 2.473E8 50.68 29.23 6 18 2860.47 33.41 8 21 431 46.1 4.48 HVO_1577 conserved hypothetical protein 33.33 1 5 5 12 9.516E7 10.35 28.81 4 6 690.81 33.33 5 6 177 19.4 4.74 HVO_2781 DNA-directed RNA polymerase subunit D 33.20 1 7 7 48 4.970E8 45.84 28.96 6 23 3277.63 33.20 7 25 259 28.1 4.32 HVO_1973 conserved hypothetical protein 32.93 1 3 3 11 6.470E7 15.04 23.95 2 5 828.23 32.93 3 6 167 18.1 4.36 HVO_0601 homoserine dehydrogenase 32.91 1 6 6 25 1.661E8 31.70 32.91 6 12 2052.27 32.91 6 13 316 32.2 4.25 HVO_0788 tryptophan synthase beta subunit 32.70 1 10 10 38 1.359E8 34.14 30.09 9 16 2110.22 32.70 10 22 422 45.7 4.65 HVO_1510 2-isopropylmalate synthase 32.50 1 9 9 42 3.696E8 46.66 31.14 8 20 2758.93 32.50 9 22 440 47.7 4.82 HVO_1198 UspA domain protein 32.41 1 4 4 14 1.177E8 9.28 32.41 4 7 830.50 32.41 4 7 145 15.6 4.75 HVO_0109 cysteine desulfurase 32.39 1 12 12 39 1.359E8 33.03 30.52 11 18 2408.61 32.39 12 21 426 46.8 4.56 HVO_2040 NAD-dependent epimerase/dehydratase 32.35 1 4 8 37 2.789E8 29.01 32.35 8 18 2350.40 32.35 8 19 306 33.8 4.51 HVO_2436 malic enzyme (NADP) 32.22 1 14 17 69 1.602E8 78.37 31.56 16 34 4477.21 32.22 17 35 751 81.4 4.55 17318569 keratin 1 [Homo sapiens] 32.14 1 1 22 103 4.613E8 115.78 32.14 21 51 7639.70 32.14 22 52 644 66.0 8.12 HVO_2643 NADPH:quinone reductase 32.08 1 7 7 38 6.354E7 29.33 32.08 7 19 2009.09 32.08 7 19 346 37.2 4.55 HVO_1018 RecJ domain protein 32.07 1 19 19 79 3.205E8 70.77 30.81 18 39 5647.54 32.07 19 40 633 69.8 4.58 HVO_1025 acetyl-CoA C-acyltransferase 31.85 1 9 9 31 1.971E8 23.05 31.85 9 15 1969.12 31.85 9 16 383 40.7 4.56 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 31.74 1 14 14 65 1.269E8 54.70 31.74 14 32 4193.55 31.74 14 33 586 63.4 4.70 HVO_0573 endonuclease IV 31.62 1 6 6 27 1.989E8 32.24 31.62 6 14 2291.25 31.62 6 13 291 31.4 4.44 HVO_1164 HD family hydrolase 31.48 1 8 8 26 7.743E7 11.71 27.41 7 12 1525.28 31.48 8 14 270 29.8 4.87 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 31.42 1 12 12 45 1.877E8 44.47 31.42 12 23 2648.06 31.42 12 22 471 51.0 4.48 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 31.35 1 6 6 16 5.534E7 14.81 26.94 5 8 650.59 22.54 5 8 386 42.1 4.49 HVO_2189 phosphoribosylformylglycinamidine synthase component PurS 31.33 1 2 2 3 2.013E7 338.39 31.33 2 3 83 9.3 4.50 HVO_1125 cysteine--tRNA ligase 31.17 1 11 11 35 9.913E7 31.82 27.53 10 17 2315.80 31.17 11 18 494 55.2 4.56 HVO_1690 DHH family phosphoesterase 31.13 1 9 9 30 1.120E8 32.18 31.13 9 15 1891.38 31.13 9 15 485 52.1 4.48 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 31.10 1 10 10 40 1.919E8 37.38 31.10 10 20 2687.39 31.10 10 20 447 48.5 4.56 HVO_1212 KaiC-type circadian regulator CirA 30.89 1 6 6 29 3.601E8 42.25 30.89 6 15 2664.84 30.89 6 14 246 27.5 4.45 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 30.78 1 25 25 103 2.213E8 92.50 28.19 23 49 7310.39 28.65 24 54 1082 117.2 4.32 HVO_2417 conserved hypothetical protein 30.77 1 4 4 17 7.621E7 18.33 27.69 3 8 1366.39 30.77 4 9 195 21.6 3.65 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 30.75 1 0 21 99 4.613E8 111.00 30.75 20 49 7355.55 30.75 21 50 644 66.0 8.12 HVO_1576 NAD-dependent epimerase/dehydratase 30.72 1 4 8 34 2.349E8 25.04 30.72 8 17 1982.48 30.72 8 17 306 33.9 4.51 HVO_0415 repair helicase 30.52 1 15 15 63 1.160E8 60.23 30.52 15 31 4162.21 30.52 15 32 616 69.6 4.70 HVO_0321 peptide chain release factor aRF-1 30.43 1 10 10 34 1.199E8 24.23 28.50 9 17 1845.00 23.43 9 17 414 46.6 4.83 HVO_2435 peptidase M24 family protein 30.43 1 7 7 31 6.859E7 23.65 30.43 7 15 2136.12 30.43 7 16 368 40.0 4.53 HVO_A0406 conserved hypothetical protein 30.37 1 2 9 25 1.159E8 16.76 27.90 8 13 1307.75 24.69 8 12 405 44.4 5.30 HVO_0911 GTP-binding protein Drg 30.35 1 9 9 27 4.601E7 20.65 25.75 8 13 1802.33 30.35 9 14 369 40.5 4.81 HVO_0549 2-keto-3-deoxygluconate kinase 30.31 1 8 9 32 1.712E8 24.40 28.13 8 16 1975.22 30.31 9 16 320 34.1 4.34 HVO_B0061 precorrin-2 C20-methyltransferase 30.21 1 5 5 13 3.055E7 5.79 30.21 5 7 468.86 30.21 5 6 235 25.3 4.63 HVO_1465 naphthoate synthase 30.16 1 6 6 27 8.114E7 25.71 30.16 6 13 1520.54 30.16 6 14 305 33.9 4.83 HVO_2721 amidophosphoribosyltransferase 30.02 1 10 10 41 4.503E8 30.37 30.02 10 20 2278.55 30.02 10 21 493 53.4 4.78 HVO_C0069 GFO family oxidoreductase 29.94 1 8 8 25 6.579E7 25.72 29.94 8 14 1300.74 29.63 7 11 324 36.0 5.10 HVO_0243 threonine aldolase 29.91 1 7 7 30 5.005E7 27.48 29.91 7 15 1617.17 29.91 7 15 341 35.6 4.55 HVO_1778 catalase-peroxidase 29.67 1 16 16 72 3.673E8 64.39 29.67 16 36 4088.21 28.97 15 36 718 80.0 4.31 HVO_0353 30S ribosomal protein S12 29.58 1 5 5 24 4.137E8 31.37 29.58 5 12 1707.85 29.58 5 12 142 15.5 9.91 HVO_0360 30S ribosomal protein S10 29.41 1 3 3 9 3.555E7 8.64 29.41 3 5 557.45 22.55 2 4 102 11.5 4.88 HVO_1488 D-gluconate dehydratase 29.37 1 8 10 63 4.410E8 62.78 29.37 10 32 3842.96 29.37 10 31 412 45.8 4.60 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 29.30 1 9 9 34 9.133E7 30.00 29.30 9 17 1832.83 29.30 9 17 430 45.1 4.50 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 29.26 1 7 7 32 1.091E8 21.45 29.26 7 16 1990.40 29.26 7 16 270 29.1 4.35 HVO_1573 DNA gyrase subunit A 29.12 1 22 22 88 2.211E8 80.35 27.73 21 44 5367.03 29.12 22 44 862 94.8 4.56 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 29.09 1 6 6 22 8.103E7 12.25 29.09 6 11 1138.49 29.09 6 11 330 36.3 4.35 HVO_2562 50S ribosomal protein L23 28.92 1 2 2 3 1.052E7 531.61 28.92 2 3 83 9.4 5.48 HVO_1496 phosphotransferase system component I 28.85 1 13 13 47 1.058E8 45.93 28.85 13 24 3059.81 28.85 13 23 565 60.3 4.21 HVO_0694 probable phosphoribosyltransferase 28.69 1 6 6 24 1.800E7 26.36 28.69 6 12 2004.04 28.69 6 12 237 27.0 4.32 HVO_1491 HAD superfamily hydrolase 28.68 1 10 10 28 4.144E7 13.47 26.47 9 14 1256.66 23.77 9 14 408 44.4 4.60 HVO_1824 conserved hypothetical protein 28.67 1 8 8 26 8.294E7 29.80 28.67 8 13 2036.95 25.17 7 13 429 47.4 4.20 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 28.67 1 8 8 37 2.920E8 28.63 28.67 8 18 2123.06 28.67 8 19 415 44.4 4.41 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 28.57 1 7 7 18 2.652E7 12.20 28.57 7 9 919.82 23.00 6 9 287 31.8 4.93 HVO_2861 conserved hypothetical protein 28.36 1 8 8 36 1.728E8 29.56 28.36 8 19 1998.95 28.36 8 17 275 29.1 4.27 HVO_0979 NADH dehydrogenase-like complex subunit B 28.33 1 5 5 20 5.588E7 11.69 28.33 5 10 960.81 28.33 5 10 233 26.1 5.01 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 28.27 1 6 6 29 1.734E8 38.81 28.27 6 15 2561.02 28.27 6 14 336 36.8 4.12 HVO_0997 peptidase M24 family protein 28.26 1 6 6 22 2.444E7 19.87 28.26 6 11 1462.58 28.26 6 11 368 39.9 4.49 HVO_1623 conserved hypothetical protein 28.19 1 5 5 17 9.307E7 19.06 17.45 4 8 1231.73 28.19 5 9 298 32.8 4.56 HVO_B0130 DUF296 family protein 28.15 1 3 3 8 2.647E7 1.82 28.15 3 5 272.44 20.74 2 3 135 14.8 4.41 HVO_0467 PhoU/TrkA-C domain protein 28.11 1 9 9 26 4.998E7 27.16 26.12 8 12 1713.31 28.11 9 14 402 43.3 4.49 HVO_2883 conserved hypothetical protein 28.06 1 15 15 44 5.559E7 42.16 25.78 14 21 2806.58 28.06 15 23 702 78.9 4.48 HVO_0357 ACT domain protein 28.04 1 5 5 18 1.207E8 20.97 28.04 5 9 1363.08 28.04 5 9 189 20.2 4.59 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 27.98 1 8 8 28 1.399E8 26.78 27.98 8 14 1458.40 27.98 8 14 336 38.0 4.61 HVO_2130 IclR family transcription regulator 27.94 1 7 7 32 6.017E7 24.21 20.96 5 13 1927.67 27.94 7 19 272 30.1 5.55 HVO_A0496 UspA domain protein 27.93 1 7 7 31 1.335E8 24.35 27.93 7 17 1506.59 27.93 7 14 290 31.4 4.60 HVO_1804 nicotinate phosphoribosyltransferase 27.84 1 8 8 24 7.536E7 27.35 24.74 7 11 1839.45 27.84 8 13 388 41.1 4.60 HVO_B0371 aldehyde dehydrogenase 27.82 1 7 7 26 3.626E7 15.10 27.82 7 13 1122.66 27.82 7 13 496 52.5 4.39 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 27.72 1 3 3 7 2.045E7 2.70 16.30 2 3 276.02 27.72 3 4 184 19.8 5.30 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 27.69 1 17 17 71 3.130E8 53.98 26.11 16 34 4845.50 27.69 17 37 697 74.5 4.13 HVO_1967 glucose-6-phosphate isomerase 27.67 1 9 9 30 7.634E7 33.31 27.67 8 14 2077.65 27.67 9 16 430 45.6 4.40 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 27.66 1 3 3 12 1.372E8 11.87 27.66 3 6 546.52 27.66 3 6 188 20.5 4.60 HVO_1545 dihydroxyacetone kinase subunit DhaL 27.59 1 5 5 19 1.967E8 19.31 27.59 5 9 1337.96 27.59 5 10 232 24.8 4.48 HVO_2225 AstE family protein 27.57 1 5 5 18 1.405E8 21.38 27.57 5 9 1230.85 27.57 5 9 341 36.9 4.53 HVO_2675 histidinol dehydrogenase 27.57 1 7 7 27 1.905E8 31.64 26.40 6 13 2050.21 27.57 7 14 428 45.4 4.50 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 27.55 1 7 7 37 1.028E8 32.11 27.55 7 19 2141.22 27.55 7 18 363 39.3 4.97 HVO_1727 TATA-binding transcription initiation factor 27.42 1 5 5 21 3.686E8 12.13 24.73 4 9 1193.94 27.42 5 12 186 19.9 4.36 HVO_0429 archaemetzincin 27.17 1 3 3 10 3.194E7 10.72 27.17 3 5 701.33 27.17 3 5 173 19.3 6.54 HVO_1880 conserved hypothetical protein 27.11 1 5 5 16 2.195E7 14.11 27.11 5 8 1048.75 27.11 5 8 225 23.8 4.59 HVO_1575 arginase 27.09 1 6 6 20 8.257E7 18.19 27.09 6 10 957.14 27.09 6 10 299 31.0 4.58 HVO_1847 oligoendopeptidase PepF 27.05 1 11 11 37 5.963E7 26.27 27.05 11 18 2015.79 27.05 11 19 599 68.5 4.41 HVO_2948 phenylalanine--tRNA ligase alpha subunit 27.05 1 6 6 29 1.309E8 29.65 27.05 6 15 1854.01 19.84 5 14 499 55.1 4.41 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 26.97 1 3 4 12 8.489E7 10.32 18.35 3 5 563.78 26.97 4 7 267 29.1 4.63 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 26.95 1 10 10 45 1.234E8 56.32 26.95 10 23 3569.58 26.95 10 22 512 53.8 4.78 HVO_2156 UspA domain protein 26.91 1 7 7 25 1.416E8 20.98 26.91 7 13 1784.13 24.25 6 12 301 31.6 4.69 HVO_1867 lysine--tRNA ligase 26.85 1 13 13 39 7.729E7 27.39 26.85 13 20 2038.48 26.85 13 19 555 62.1 4.46 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 26.65 1 9 9 41 1.540E8 46.21 26.65 9 21 3291.86 26.65 9 20 364 39.3 4.35 HVO_1080 conserved hypothetical protein 26.60 1 5 5 20 1.136E8 19.15 26.60 5 10 1349.84 26.60 5 10 188 21.1 4.31 HVO_2690 GFO family oxidoreductase 26.50 1 8 8 39 3.074E8 29.13 26.50 8 20 2325.39 26.50 8 19 366 40.0 4.60 HVO_1020 HEAT-PBS family protein 26.49 1 9 9 31 1.383E8 27.94 24.82 8 14 2785.92 26.49 9 17 419 45.5 3.95 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 26.49 1 11 11 56 4.178E8 27.41 26.49 11 28 3108.76 23.51 10 28 370 41.9 4.48 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 26.41 1 7 7 23 4.513E7 15.54 20.77 6 11 1461.71 26.41 7 12 337 35.9 4.69 HVO_2639 DUF1611 family protein 26.39 1 6 6 21 4.790E7 20.51 26.39 6 11 1291.66 16.13 5 10 341 36.3 4.44 HVO_1570 DNA topoisomerase VI subunit A 26.23 1 7 7 21 1.078E8 16.40 26.23 7 11 1123.35 22.40 5 10 366 41.8 4.63 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 14 8.207E7 9.82 26.15 3 7 824.72 26.15 3 7 130 13.4 8.56 HVO_C0001 Orc1-type DNA replication protein 25.98 1 10 10 28 4.227E7 22.08 25.98 10 14 1514.41 25.98 10 14 408 45.2 4.97 HVO_2496 adenylate kinase 25.96 1 4 4 18 1.748E8 15.25 25.96 4 9 1140.10 25.96 4 9 208 23.1 4.25 HVO_2547 50S ribosomal protein L32e 25.96 1 4 4 16 5.878E7 15.68 18.72 3 7 1347.99 25.96 4 9 235 25.8 4.75 HVO_2706 translation initiation factor aIF-2B delta subunit 25.89 1 6 6 19 1.005E8 8.37 25.89 6 8 1018.19 25.89 6 11 282 30.7 4.42 HVO_1654 cysteine synthase 25.82 1 7 7 23 1.206E8 18.79 25.49 6 11 1505.06 25.82 7 12 306 32.3 4.32 HVO_1481 UspA domain protein 25.77 1 3 3 14 7.746E7 9.61 25.77 3 7 629.61 25.77 3 7 163 17.7 4.40 HVO_2777 30S ribosomal protein S9 25.76 1 3 3 8 1.385E7 9.25 25.76 3 4 625.23 25.76 3 4 132 14.7 9.74 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 25.68 1 12 13 41 1.701E8 49.19 25.36 12 20 2909.53 25.68 13 21 623 62.1 5.30 7428712 "keratin 1, type II, cytoskeletal - human" 25.66 1 0 18 89 3.770E8 103.98 25.66 17 44 6818.06 25.66 18 45 643 65.5 6.35 HVO_1189 aldehyde dehydrogenase 25.59 1 11 11 43 4.156E8 40.67 23.82 10 21 2484.68 25.59 11 22 508 56.1 4.59 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 25.31 1 5 5 20 1.839E8 15.52 25.31 5 10 1364.46 25.31 5 10 324 33.6 3.99 HVO_1901 translation initiation factor aIF-2 gamma subunit 25.30 1 9 9 56 5.548E8 28.36 20.19 8 27 2953.48 25.30 9 29 411 43.9 4.36 HVO_1048 phosphoribosylformylglycinamidine synthase 2 25.21 1 12 12 63 3.312E8 69.24 24.22 11 30 4576.98 25.21 12 33 702 72.9 4.18 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 25.21 1 3 3 7 4.147E7 4.49 25.21 3 3 373.70 25.21 3 4 238 24.7 4.15 >sp|TRYP_PIG| 25.11 1 4 4 58 9.385E9 72.24 25.11 4 29 4856.62 25.11 4 29 231 24.4 7.18 HVO_0401 UspA domain protein 25.00 1 3 3 10 7.001E7 7.00 25.00 3 5 543.27 25.00 3 5 152 16.4 4.79 HVO_2300 translation initiation factor aIF-5A 25.00 1 2 2 16 5.180E8 17.42 25.00 2 8 1139.59 25.00 2 8 124 14.2 5.22 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 24.95 1 9 9 24 1.203E8 22.30 22.41 8 11 1464.60 24.95 9 13 473 50.8 4.58 HVO_0916 diphthine synthase 24.91 1 5 5 18 8.732E7 12.77 24.91 5 9 998.65 24.91 5 9 269 29.1 4.54 HVO_0867 HD family hydrolase 24.78 1 5 5 13 2.942E7 2.37 24.78 5 7 494.76 18.70 4 6 230 26.2 4.78 HVO_0889 FAD-dependent oxidoreductase 24.77 1 3 3 14 4.653E7 15.98 24.77 3 7 1207.34 24.77 3 7 214 21.8 3.89 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 24.67 1 7 7 29 9.061E7 30.08 24.67 7 14 1811.70 24.67 7 15 454 48.5 4.46 HVO_0658 tRNA pseudouridine(13) synthase TruD 24.62 1 8 8 27 4.063E7 22.60 22.25 7 13 1380.05 24.62 8 14 463 50.6 4.70 HVO_1373 acyl-CoA dehydrogenase 24.54 1 6 6 12 3.164E7 8.39 22.72 5 6 599.72 20.89 5 6 383 42.5 4.61 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 24.50 1 12 12 42 8.469E7 42.62 24.50 12 21 2589.24 24.50 12 21 706 73.3 4.39 HVO_0552 DNA mismatch repair protein MutS 24.46 1 16 16 52 8.194E7 49.34 23.05 15 26 2880.96 22.08 15 26 924 99.2 4.65 HVO_2153 probable copper-containing oxidoreductase 24.42 1 7 7 20 4.120E7 17.48 24.42 7 10 1186.29 24.42 7 10 385 42.1 5.82 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 24.29 1 7 7 23 2.982E7 13.44 24.29 7 11 1249.05 24.29 7 12 420 45.0 4.86 HVO_2580 L-aspartate oxidase 24.21 1 10 10 34 1.009E8 36.18 24.21 10 17 2293.58 24.21 10 17 537 55.8 4.63 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 24.03 1 6 6 16 1.409E8 17.88 20.99 5 7 1307.08 24.03 6 9 362 39.6 4.82 HVO_0829 peptidase S9 family protein 24.01 1 10 10 26 5.129E7 13.73 24.01 10 13 901.59 22.20 9 13 608 67.4 4.54 HVO_0049 argininosuccinate synthase 23.95 1 10 10 41 4.884E8 29.45 22.47 9 19 2171.41 23.95 10 22 405 44.5 4.34 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 23.91 1 7 7 36 4.375E8 34.10 23.91 7 18 2866.86 23.91 7 18 435 46.9 4.63 HVO_1508 acetolactate synthase large subunit 23.85 1 8 8 29 1.851E8 32.97 23.85 8 15 2219.97 23.85 8 14 587 62.3 4.36 HVO_2947 phenylalanine--tRNA ligase beta subunit 23.68 1 9 9 30 1.786E8 21.72 21.75 8 14 2101.19 23.68 9 16 570 63.3 4.46 HVO_1356 sensor box histidine kinase 23.64 1 8 8 17 4.337E7 13.90 18.91 7 8 727.36 21.27 7 9 550 61.1 4.60 HVO_1175 DUF2110 family protein 23.56 1 5 5 16 2.599E8 15.66 23.56 5 8 1062.85 23.56 5 8 225 24.4 4.63 HVO_1871 UPF0447 family protein 23.55 1 9 9 37 1.227E8 37.00 20.16 8 17 2119.18 23.55 9 20 501 56.1 4.59 HVO_0697 PAC2 family protein 23.53 1 3 3 20 1.037E8 26.93 23.53 3 10 1792.09 23.53 3 10 255 27.4 4.08 HVO_2313 siroheme decarboxylase AhbB 23.51 1 4 4 13 6.881E7 18.64 23.51 4 7 941.41 17.56 3 6 353 39.6 4.64 HVO_1547 isoleucine--tRNA ligase 23.49 1 17 17 62 1.981E8 65.15 21.86 15 32 3688.20 22.24 16 30 1043 117.9 4.30 HVO_1527 glucose-1-phosphate uridylyltransferase 23.46 1 5 5 21 1.590E8 14.81 23.46 5 11 1061.81 23.46 5 10 243 27.5 4.70 HVO_1348 probable YjeF family carbohydrate kinase 23.43 1 8 8 30 3.100E7 33.75 23.43 8 15 1989.75 23.43 8 15 478 48.8 4.45 HVO_0123 signal recognition particle 54K protein 23.23 1 8 8 26 6.044E7 15.41 21.08 7 12 1195.05 23.23 8 14 465 50.9 4.50 HVO_A0331 D-galactonate dehydratase 23.18 1 6 6 27 6.955E7 14.22 23.18 6 13 1277.49 23.18 6 14 384 42.8 4.83 HVO_2759 peptidase M42 family protein 23.16 1 6 6 28 7.311E7 19.22 23.16 6 14 1467.84 23.16 6 14 354 37.0 4.40 HVO_0812 phosphoenolpyruvate synthase 23.13 1 17 17 57 7.376E7 38.62 20.89 15 27 3514.64 23.13 17 30 761 83.1 4.63 HVO_1660 DisA-N domain protein 23.05 1 5 5 22 1.193E8 26.28 23.05 5 11 1756.45 23.05 5 11 269 28.9 4.73 HVO_2784 30S ribosomal protein S13 22.75 1 3 3 8 6.477E7 6.93 22.75 3 4 519.45 22.75 3 4 167 18.9 5.17 HVO_0484 50S ribosomal protein L10e 22.73 1 3 3 8 4.297E7 6.65 22.73 3 4 397.01 22.73 3 4 176 19.8 8.72 HVO_2554 50S ribosomal protein L14 22.73 1 3 3 7 1.051E8 2.48 13.64 2 3 371.75 22.73 3 4 132 14.2 9.76 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 22.66 1 2 2 6 3.126E7 5.43 22.66 2 3 480.00 22.66 2 3 128 13.0 4.31 HVO_0681 DNA topoisomerase I 22.62 1 15 15 46 5.588E7 37.17 22.02 14 22 2763.66 22.62 15 24 840 93.6 4.58 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 22.53 1 5 5 15 1.023E8 9.33 17.79 4 7 570.26 22.53 5 8 253 26.0 4.60 HVO_B0149 oleate hydratase 22.51 1 8 9 26 1.048E8 13.46 19.14 7 11 1413.64 20.08 8 15 533 60.1 4.64 HVO_2333 conserved hypothetical protein 22.08 1 4 4 8 2.701E7 4.47 22.08 4 4 239.27 22.08 4 4 308 34.9 4.54 HVO_1571 DNA topoisomerase VI subunit B 22.06 1 11 11 39 1.625E8 39.07 17.67 9 19 2796.40 22.06 11 20 798 87.4 4.73 HVO_1295 histidinol-phosphate aminotransferase 21.88 1 6 6 23 8.179E7 16.68 19.67 5 11 1515.59 21.88 6 12 361 39.4 4.51 HVO_2952 tRNA-splicing endonuclease 21.83 1 5 5 7 1.895E7 2.85 14.75 4 4 167.54 14.45 3 3 339 37.4 4.74 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 21.80 1 8 8 25 5.833E7 16.80 14.83 6 11 1770.12 21.80 8 14 344 39.1 4.73 HVO_1478 transcription initiation factor TFB 21.77 1 4 7 30 1.787E8 28.86 21.77 7 15 1936.15 21.77 7 15 317 35.7 5.47 HVO_0354 30S ribosomal protein S7 21.57 1 4 4 16 1.176E8 19.10 21.57 4 8 1289.21 21.57 4 8 204 22.6 5.14 HVO_2348 GTP cyclohydrolase MptA 21.43 1 4 4 20 1.239E8 11.45 21.43 4 10 744.87 13.31 3 10 308 33.5 4.68 HVO_0214 L-lactate dehydrogenase 21.25 1 7 7 28 5.606E8 26.84 19.69 6 13 1984.66 21.25 7 15 320 34.5 4.49 HVO_0406 RNA-binding protein AU-1 21.15 1 7 7 24 4.970E7 22.46 21.15 7 12 1358.60 21.15 7 12 468 49.9 4.53 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 21.09 1 4 4 12 3.169E7 4.92 21.09 4 6 420.39 21.09 4 6 294 32.5 4.75 HVO_2481 HD family hydrolase 21.03 1 5 5 7 3.358E7 0.00 9.49 2 2 189.67 21.03 5 5 390 42.7 6.14 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 21.01 1 5 5 19 1.142E8 17.10 21.01 5 10 1190.76 21.01 5 9 357 39.8 4.41 HVO_2564 50S ribosomal protein L3 21.01 1 5 5 20 5.656E7 21.11 21.01 5 10 1354.08 21.01 5 10 338 37.2 6.68 HVO_B0084 conserved hypothetical protein 21.01 1 2 2 4 9.362E6 1.78 21.01 2 2 159.94 21.01 2 2 138 14.3 4.70 HVO_0122 phosphoglycerate dehydrogenase 20.99 1 5 5 15 5.252E7 13.44 20.99 5 8 891.90 19.14 4 7 324 35.3 5.35 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 20.88 1 2 2 6 1.502E7 4.07 20.88 2 3 266.13 20.88 2 3 91 10.4 4.07 HVO_2008 archaeosine synthase 20.85 1 9 9 27 1.621E8 19.39 19.66 8 13 1667.12 20.85 9 14 585 64.9 4.81 HVO_1979 tRNA pseudouridine synthase Pus10 20.84 1 7 7 32 1.443E8 26.34 20.84 7 16 2070.41 20.84 7 16 427 46.9 4.39 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 20.80 1 6 6 12 2.412E7 6.46 17.13 5 6 689.58 20.80 6 6 327 36.0 4.73 HVO_2548 50S ribosomal protein L6 20.79 1 3 3 8 2.879E7 8.54 20.79 3 4 558.12 20.79 3 4 178 19.6 4.68 HVO_2960 dihydrolipoamide S-acyltransferase 20.73 1 9 9 33 7.201E7 18.81 20.73 9 17 1736.34 19.19 8 16 521 54.9 4.40 HVO_2347 conserved hypothetical protein 20.71 1 2 2 6 2.134E7 7.29 20.71 2 3 407.69 20.71 2 3 140 15.5 4.37 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 6 2.349E7 5.84 20.71 2 3 330.92 20.71 2 3 140 16.0 5.57 HVO_2790 ATP-binding protein Mrp 20.52 1 4 4 16 6.896E7 18.98 20.52 4 8 1332.43 20.52 4 8 346 36.8 4.50 HVO_2716 acyl-CoA dehydrogenase 20.47 1 5 5 20 3.334E7 25.41 20.47 5 10 1294.22 20.47 5 10 381 41.3 4.65 HVO_2239 UspA domain protein 20.42 1 3 3 12 5.491E7 11.94 20.42 3 6 854.01 20.42 3 6 142 15.4 4.16 HVO_1453 glutamate dehydrogenase (NADP) 20.38 1 7 7 21 8.313E7 13.37 18.47 6 10 1352.37 20.38 7 11 417 45.7 4.49 HVO_2648 phosphoglycerate dehydrogenase 20.38 1 6 6 16 3.692E7 11.89 17.55 5 8 1028.72 18.18 5 8 319 34.2 4.64 HVO_A0636 YbaK domain protein 20.25 1 2 2 4 3.215E7 1.81 20.25 2 2 199.64 20.25 2 2 158 16.7 4.54 HVO_0675 pantoate kinase 20.22 1 5 5 14 3.144E7 6.46 20.22 5 8 527.15 16.25 4 6 277 27.8 4.54 HVO_1546 dihydroxyacetone kinase subunit DhaK 20.18 1 7 7 33 2.117E8 29.67 20.18 7 16 2052.79 20.18 7 17 332 34.8 4.22 HVO_0837 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 20.16 1 4 4 9 1.535E7 10.08 16.05 3 4 479.67 20.16 4 5 243 24.8 4.48 HVO_1578 probable NADH dehydrogenase 20.15 1 4 4 12 6.454E7 8.22 20.15 4 6 466.58 20.15 4 6 397 42.8 4.40 HVO_1134 conserved hypothetical protein 20.08 1 12 12 35 7.490E7 34.64 18.76 11 17 2410.57 18.63 11 18 757 80.6 4.35 HVO_1412 diphosphomevalonate decarboxylase 20.06 1 7 7 38 3.911E8 20.26 20.06 7 19 1962.05 20.06 7 19 324 35.4 4.78 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 19.94 1 21 21 71 9.757E7 60.22 18.69 20 35 3886.93 19.94 21 36 1284 141.2 4.35 HVO_2380 AAA-type ATPase (CDC48 subfamily) 19.92 1 11 11 34 4.657E7 26.65 19.11 10 17 1767.91 17.90 10 17 743 81.9 4.82 HVO_1657 phosphoribosylamine--glycine ligase 19.86 1 9 9 55 4.680E8 32.49 19.86 9 27 3143.77 19.86 9 28 428 45.5 4.20 HVO_2779 50S ribosomal protein L18e 19.83 1 3 3 10 1.514E7 7.21 19.83 3 5 497.74 19.83 3 5 116 12.7 8.50 HVO_A0432 conserved hypothetical protein 19.75 1 0 7 22 1.159E8 16.76 17.28 6 11 1252.48 19.75 7 11 405 44.5 5.24 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 19.71 1 3 3 12 3.248E7 16.08 19.71 3 7 831.41 13.94 2 5 208 22.6 4.36 HVO_1299 HTH domain protein 19.65 1 3 3 8 2.863E7 5.60 19.65 3 4 283.05 19.65 3 4 173 18.9 4.84 HVO_2383 DNA repair and recombination protein RadB 19.65 1 4 4 16 2.582E7 8.86 19.65 4 8 709.20 19.65 4 8 229 24.6 5.02 HVO_1300 triosephosphate isomerase 19.63 1 4 4 41 6.445E8 48.48 19.63 4 20 3300.03 19.63 4 21 214 21.3 4.26 HVO_2717 alanine--tRNA ligase 19.60 1 6 6 23 4.714E7 15.46 16.58 5 11 1296.66 19.60 6 12 398 41.6 4.39 HVO_1878 NAD synthase 19.57 1 5 5 26 7.453E7 16.52 19.57 5 12 1504.04 19.57 5 14 276 29.6 4.37 HVO_0466 citrate (si)-synthase 19.53 1 7 7 37 2.557E8 43.32 17.94 6 18 2852.17 19.53 7 19 379 41.8 4.55 HVO_A0133 conserved hypothetical protein 19.52 1 4 4 13 4.509E7 11.66 19.52 4 7 691.84 14.38 3 6 292 30.8 5.17 HVO_2543 50S ribosomal protein L30 19.48 1 2 2 7 1.674E7 4.05 19.48 2 3 267.18 19.48 2 4 154 17.1 4.77 HVO_1327 AAA-type ATPase (CDC48 subfamily) 19.43 1 9 10 34 6.319E7 15.44 19.43 10 16 1648.07 19.43 10 18 736 78.1 4.88 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 19.36 1 4 4 19 1.192E8 25.17 19.36 4 9 1558.55 19.36 4 10 377 39.2 4.18 HVO_2712 3'-5' RNA ligase 19.34 1 7 7 21 4.961E7 13.31 19.34 7 11 1194.71 15.02 6 10 486 53.4 4.92 HVO_0044 acetylglutamate kinase 19.27 1 5 5 16 1.179E8 21.41 19.27 5 8 1341.72 19.27 5 8 327 33.2 4.49 HVO_0699 translation initiation factor aIF-2 alpha subunit 19.17 1 4 4 20 1.096E8 19.27 19.17 4 10 1187.19 19.17 4 10 266 29.5 4.46 HVO_2168 AAA-type ATPase (MoxR subfamily) 19.15 1 4 4 14 4.480E7 12.71 19.15 4 7 854.99 19.15 4 7 329 35.9 4.54 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 19.13 1 5 5 13 3.428E7 15.13 19.13 5 6 786.11 19.13 5 7 345 36.9 4.68 HVO_2951 tryptophan--tRNA ligase 19.09 1 7 7 18 5.902E7 14.17 13.80 5 9 702.70 17.58 6 9 529 59.1 4.53 HVO_1531 UDP-glucose 6-dehydrogenase 19.07 1 8 8 32 8.226E7 27.73 19.07 8 16 1903.12 19.07 8 16 430 45.9 4.50 HVO_A0087 fumarylacetoacetase family protein 19.03 1 4 4 19 1.277E8 17.42 19.03 4 10 1193.69 19.03 4 9 289 32.0 4.21 HVO_2688 TrmB family transcription regulator 18.98 1 5 5 16 1.580E8 18.88 18.98 5 9 1173.83 17.28 4 7 353 39.3 4.58 HVO_1289 OsmC domain protein 18.94 1 2 2 8 2.411E8 12.11 18.94 2 4 904.43 18.94 2 4 132 14.2 3.85 HVO_0417 metal-dependent carboxypeptidase 18.92 1 8 8 27 1.028E8 26.83 18.92 8 13 1912.58 18.92 8 14 502 57.3 4.42 HVO_0034 acyl-CoA thioester hydrolase 18.90 1 2 2 16 1.063E8 16.06 18.90 2 8 882.21 18.90 2 8 164 18.3 4.65 HVO_1816 dihydroorotase 18.88 1 5 5 22 3.940E7 20.40 18.88 5 11 1420.22 18.88 5 11 429 45.4 4.40 HVO_0970 ribulose-bisphosphate carboxylase large subunit 18.84 1 6 6 40 6.796E7 37.58 18.84 6 20 2579.29 18.84 6 20 414 43.9 4.59 HVO_1097 diaminopimelate epimerase 18.75 1 4 4 18 2.749E7 20.53 15.28 3 8 1287.61 18.75 4 10 288 29.9 4.48 HVO_1957 proteasome-activating nucleotidase 18.69 1 6 6 18 5.154E7 6.04 18.69 6 9 663.90 18.69 6 9 412 45.6 4.48 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 18.61 1 5 5 19 1.450E8 20.24 15.56 4 9 1568.71 18.61 5 10 360 38.5 4.45 HVO_0326 CTP-dependent riboflavin kinase 18.57 1 4 4 11 2.790E7 6.92 14.35 3 5 721.37 18.57 4 6 237 25.9 4.55 HVO_1866 uridylate kinase 18.57 1 4 4 20 2.035E8 12.36 18.57 4 9 1194.63 18.57 4 11 237 24.6 4.42 HVO_2763 homolog to ribonuclease Z 18.55 1 4 4 15 2.417E7 3.86 18.55 4 7 458.56 16.13 3 8 248 26.6 4.53 HVO_2536 CHP00300 family protein 18.51 1 5 5 14 4.256E7 2.60 15.63 4 6 557.49 18.51 5 8 416 44.8 4.51 HVO_A0266 IclR family transcription regulator 18.43 1 4 4 16 3.824E7 13.93 18.43 4 8 1079.07 18.43 4 8 255 27.7 6.05 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 18.36 1 4 4 10 2.351E7 7.46 18.36 4 5 369.60 18.36 4 5 305 34.1 4.91 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 16 8.378E7 18.43 18.29 4 8 1277.15 18.29 4 8 257 26.8 4.01 HVO_2427 replication factor C large subunit 18.24 1 8 8 28 2.365E7 29.37 18.24 8 14 1807.55 18.24 8 14 488 53.4 4.67 HVO_A0307 Lrp/AsnC family transcription regulator 18.08 1 3 3 6 1.122E7 4.56 18.08 3 3 347.47 18.08 3 3 177 19.4 4.39 HVO_0156 "tRNA (guanine(10),N(2))-dimethyltransferase" 18.07 1 5 5 12 1.529E7 12.23 18.07 5 6 738.38 18.07 5 6 321 34.2 5.25 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 17.99 1 3 3 13 5.879E7 3.99 17.99 3 6 545.63 17.99 3 7 189 21.7 4.46 HVO_1949 conserved hypothetical protein 17.92 1 2 2 2 2.085E7 95.51 17.92 2 2 173 18.6 4.27 HVO_0452 leucine--tRNA ligase 17.85 1 11 11 45 1.946E8 44.45 17.85 11 22 3023.69 17.85 11 23 958 109.5 4.37 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 17.84 1 3 3 12 9.106E7 8.43 17.84 3 6 684.14 17.84 3 6 269 28.3 4.49 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 17.82 1 3 3 7 2.420E7 0.00 17.82 3 3 182.84 17.82 3 4 348 36.7 4.69 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 17.82 1 8 8 19 4.530E7 16.02 17.82 8 10 1345.48 16.72 7 9 634 66.1 4.54 HVO_B0055 conserved hypothetical protein 17.78 1 4 4 16 4.480E7 13.44 17.78 4 8 805.20 17.78 4 8 225 23.9 4.69 HVO_2879 ornithine cyclodeaminase 17.77 1 4 4 18 9.565E7 12.16 10.24 3 7 826.49 17.77 4 11 332 34.6 4.45 HVO_B0018 ParA domain protein 17.77 1 3 3 8 3.198E7 0.00 17.77 3 4 219.36 17.77 3 4 287 31.7 4.74 HVO_0120 signal recognition particle receptor FtsY 17.76 1 5 5 17 3.993E7 16.71 17.76 5 9 1158.40 14.69 4 8 456 48.2 4.17 HVO_2945 valine--tRNA ligase 17.70 1 12 12 43 1.918E8 23.67 16.21 11 21 2167.51 17.70 12 22 870 98.9 4.36 HVO_0233 ribose-phosphate pyrophosphokinase 17.67 1 4 4 12 5.828E7 11.73 17.67 4 6 633.30 17.67 4 6 283 29.6 4.40 HVO_2965 phosphoserine phosphatase 17.67 1 2 2 8 2.456E7 6.32 17.67 2 4 335.91 17.67 2 4 215 23.2 4.51 HVO_1337 rpa-associated protein 17.66 1 8 8 28 1.893E8 23.71 17.66 8 13 1618.10 17.66 8 15 623 64.8 3.68 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 17.65 1 6 6 27 1.089E8 17.17 17.65 6 14 1502.60 10.95 5 13 612 67.3 4.16 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 17.58 1 5 5 24 2.385E8 16.69 17.58 5 12 1025.58 17.58 5 12 347 36.8 4.93 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 17.56 1 7 7 30 1.137E8 32.66 17.56 7 15 1994.91 17.56 7 15 615 67.6 4.88 HVO_A0021 conserved hypothetical protein 17.56 1 2 2 3 2.789E7 321.10 17.56 2 3 131 14.9 4.42 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 17.46 1 4 4 16 2.012E8 15.50 17.46 4 8 1080.20 17.46 4 8 252 26.0 4.39 HVO_B0345 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 17.46 1 4 4 6 1.165E7 2.28 14.55 3 3 166.34 9.79 3 3 378 41.2 4.84 HVO_0048 argininosuccinate lyase 17.42 1 7 7 16 4.617E7 11.64 17.42 7 8 730.44 17.42 7 8 488 50.8 4.53 HVO_2708 YfiH family protein 17.39 1 4 4 13 9.138E7 17.37 17.39 4 6 1138.34 17.39 4 7 322 35.4 4.35 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 17.36 1 4 4 14 2.573E7 14.83 17.36 4 7 1019.49 17.36 4 7 265 29.3 4.92 HVO_2205 arNOG06768 family NADH-binding domain protein 17.28 1 4 4 12 2.219E7 15.72 17.28 4 6 737.74 17.28 4 6 301 32.0 5.00 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 17.23 1 3 4 14 4.186E7 12.76 17.23 4 7 783.58 17.23 4 7 267 28.8 4.55 HVO_0787 indole-3-glycerol-phosphate synthase 17.13 1 3 3 8 2.398E7 5.93 17.13 3 4 470.70 17.13 3 4 251 26.7 4.44 HVO_A0486 hydrogenase expression/formation protein 16.96 1 3 3 11 1.375E7 6.35 16.96 3 6 542.10 16.96 3 5 336 33.8 4.06 HVO_1562 proteasome beta subunit 16.87 1 3 3 11 1.482E8 11.16 12.76 2 5 807.08 16.87 3 6 243 26.0 4.63 HVO_2467 NADPH:quinone reductase 16.82 1 4 4 16 7.972E7 13.94 16.82 4 8 901.35 16.82 4 8 321 33.0 4.51 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 16.72 1 4 4 15 1.054E8 12.49 16.72 4 7 971.86 16.72 4 8 299 32.0 4.53 HVO_0043 acetylornithine aminotransferase 16.67 1 4 4 21 4.944E8 27.34 16.67 4 11 1687.51 12.96 3 10 378 39.7 4.67 HVO_0054 glycine--tRNA ligase 16.67 1 6 6 24 4.579E8 29.60 14.31 5 11 2151.23 16.67 6 13 594 64.9 4.21 HVO_B0115 fumarylacetoacetase family protein 16.61 1 3 3 10 1.946E7 15.10 16.61 3 5 800.08 16.61 3 5 283 30.3 4.21 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 16.56 1 7 7 25 3.043E7 18.33 16.56 7 12 1514.20 16.56 7 13 459 50.5 4.63 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 16.52 1 5 5 22 6.262E7 21.20 16.52 5 11 1693.53 16.52 5 11 333 36.7 4.56 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 16.47 1 0 2 10 2.686E8 5.23 16.47 2 5 306.09 16.47 2 5 85 10.0 5.94 HVO_0795 transcription initiation factor TFB 16.42 1 3 5 20 9.675E7 17.33 16.42 5 10 1164.48 16.42 5 10 335 37.4 5.59 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 16.39 1 3 3 16 2.353E7 9.31 16.39 3 8 778.60 16.39 3 8 305 32.7 4.56 HVO_1344 SBDS family protein 16.39 1 3 3 5 1.047E7 4.74 11.76 2 2 254.03 16.39 3 3 238 26.5 4.51 HVO_0853 DNA double-strand break repair protein Mre11 16.33 1 4 4 8 3.226E7 7.79 10.88 3 4 418.27 12.24 3 4 441 48.1 4.39 HVO_2072 S-layer glycoprotein 16.32 1 6 6 51 8.033E8 46.23 16.32 6 29 1907.45 16.32 6 22 827 85.1 3.65 HVO_0879 DUF371 family protein 16.31 1 2 2 10 1.073E7 6.32 16.31 2 5 509.29 16.31 2 5 141 15.3 4.65 HVO_1500 1-phosphofructokinase 16.07 1 4 4 18 2.554E7 7.82 16.07 4 9 737.66 16.07 4 9 305 32.0 4.51 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 16.01 1 4 4 11 1.553E7 5.10 12.07 3 5 490.13 16.01 4 6 406 43.1 4.60 HVO_2416 TatD-related deoxyribonuclease 15.96 1 2 2 2 7.973E6 0.00 15.96 2 2 282 30.8 4.75 HVO_0551 DNA mismatch repair protein MutL 15.78 1 9 9 23 2.665E7 11.07 13.61 8 11 842.62 15.78 9 12 735 78.7 4.50 HVO_1725 Orc1-type DNA replication protein 15.71 1 5 6 14 1.935E7 5.31 13.22 5 5 977.87 15.71 6 9 401 44.5 5.19 HVO_1710 alpha amylase 15.66 1 8 8 21 3.502E7 10.80 15.66 8 11 964.86 9.01 7 10 677 75.0 4.45 HVO_2913 superoxide dismutase (Mn) 15.58 1 0 3 14 5.449E8 15.79 15.58 3 7 1041.05 15.58 3 7 199 22.3 4.48 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 15.55 1 5 5 18 1.786E8 15.22 15.55 5 9 1155.93 15.55 5 9 373 40.2 4.44 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 15.53 1 3 3 7 2.808E7 8.59 10.50 2 3 597.50 15.53 3 4 219 22.4 4.06 HVO_A0475 superoxide dismutase (Mn) 15.50 1 0 3 14 5.449E8 15.79 15.50 3 7 1041.05 15.50 3 7 200 22.4 4.45 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 15.41 1 6 6 49 7.381E8 59.84 15.41 6 24 3260.28 15.41 6 25 357 40.3 4.40 HVO_A0485 aminotransferase class V 15.38 1 4 4 16 5.002E7 19.46 15.38 4 8 1077.21 15.38 4 8 351 37.3 4.26 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 15.38 1 5 5 13 2.037E7 5.85 13.12 4 6 633.48 15.38 5 7 442 46.9 4.58 HVO_2581 quinolinate synthase A 15.32 1 5 5 18 1.058E8 15.87 15.32 5 9 948.61 15.32 5 9 385 42.0 4.41 HVO_0195 ribose-5-phosphate isomerase 15.22 1 3 3 10 5.199E7 6.71 15.22 3 5 599.93 15.22 3 5 230 23.2 4.54 HVO_2001 tRNA-guanine(15) transglycosylase 15.12 1 5 5 15 3.129E7 16.18 15.12 5 8 1016.98 13.18 4 7 516 56.3 4.59 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 15.04 1 0 8 30 1.893E8 24.70 15.04 8 15 1423.24 15.04 8 15 472 51.6 5.16 HVO_0042 acetylornithine deacetylase 14.96 1 4 4 18 1.380E8 9.79 14.96 4 9 829.72 14.96 4 9 381 41.0 4.34 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 14.94 1 3 3 8 1.855E7 2.96 14.94 3 4 428.70 14.94 3 4 241 26.1 4.58 HVO_1501 DeoR family transcription regulator GlpR 14.90 1 3 3 7 1.834E7 7.27 14.90 3 4 393.43 9.80 2 3 255 28.0 4.97 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 14.90 1 5 5 22 3.660E7 18.14 14.90 5 11 1089.15 14.90 5 11 349 37.0 4.70 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 14.89 1 6 6 19 5.540E7 16.98 14.89 6 10 954.71 14.89 6 9 423 43.9 4.31 HVO_1291 fumarylacetoacetase family protein 14.81 1 2 2 10 2.436E8 10.04 14.81 2 5 520.67 14.81 2 5 243 26.3 4.55 HVO_A0476 conserved hypothetical protein 14.80 1 4 4 10 1.344E7 8.21 14.80 4 5 629.05 14.80 4 5 331 35.4 4.26 HVO_A0228 5'-nucleotidase SurE 14.78 1 2 2 8 3.249E7 7.98 14.78 2 4 645.23 14.78 2 4 291 31.5 4.59 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 14.76 1 3 3 5 9.353E6 1.97 7.52 2 2 246.68 14.76 3 3 359 39.4 4.91 HVO_1783 conserved hypothetical protein 14.73 1 2 2 6 1.349E7 7.58 14.73 2 3 388.56 14.73 2 3 224 24.1 5.90 HVO_0402 DUF124 family protein 14.67 1 2 2 2 4.090E7 147.52 14.67 2 2 225 24.0 4.58 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 14.63 1 2 2 3 7.360E7 299.93 14.63 2 3 376 41.8 4.91 HVO_2266 hypothetical protein 14.60 1 6 6 24 7.301E7 12.10 14.60 6 11 1368.31 14.60 6 13 493 56.7 4.54 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 14.60 1 4 4 21 1.605E8 11.10 14.60 4 10 1003.43 14.60 4 11 363 39.7 4.25 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 14.59 1 4 4 12 4.391E7 8.49 14.59 4 6 605.31 14.59 4 6 329 36.3 4.49 HVO_2068 "FtsZ family protein, type III" 14.59 1 3 3 7 4.214E7 10.72 9.19 2 3 676.72 14.59 3 4 370 38.7 4.49 HVO_0388 homolog to ribonuclease R 14.58 1 8 8 29 6.727E7 35.23 14.58 8 14 2087.20 14.58 8 15 439 50.3 4.73 HVO_1391 NUDIX family hydrolase 14.57 1 2 2 3 3.164E7 307.32 14.57 2 3 151 17.4 5.01 HVO_0511 NAD-dependent epimerase/dehydratase 14.50 1 3 3 7 4.330E7 3.45 14.50 3 4 317.62 14.50 3 3 262 29.3 4.78 HVO_2373 30S ribosomal protein S8e 14.40 1 2 2 6 3.291E7 3.61 14.40 2 3 307.96 14.40 2 3 125 13.6 10.48 HVO_B0026 probable oxidoreductase (short-chain dehydrogenase family) 14.40 1 2 2 6 1.993E7 4.68 14.40 2 3 233.60 14.40 2 3 257 26.7 4.55 HVO_2456 anthranilate phosphoribosyltransferase 14.20 1 3 3 12 6.938E7 9.37 14.20 3 6 723.53 14.20 3 6 331 33.8 4.35 HVO_2600 methionyl aminopeptidase 13.85 1 4 4 14 7.113E7 12.11 9.80 3 6 1041.99 13.85 4 8 296 32.3 4.41 HVO_0469 AstE family protein 13.84 1 3 3 8 2.987E7 8.17 13.84 3 4 507.87 13.84 3 4 318 33.9 5.85 HVO_2758 50S ribosomal protein L11 13.84 1 2 2 3 7.522E7 425.68 13.84 2 3 159 16.8 4.04 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 13.76 1 6 6 17 2.447E7 18.61 13.76 6 8 1272.98 13.76 6 9 516 56.7 4.89 HVO_0712 shikimate dehydrogenase (nonfunctional) 13.75 1 2 2 4 2.030E7 2.05 13.75 2 2 136.72 13.75 2 2 269 27.7 4.65 HVO_0194 Orc1-type DNA replication protein 13.64 1 5 5 14 1.947E7 4.98 13.64 5 7 411.57 13.64 5 7 374 42.2 4.94 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 13.61 1 4 4 14 5.239E7 8.99 13.61 4 7 672.18 13.61 4 7 360 39.5 4.31 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 13.53 1 1 7 26 1.893E8 22.45 13.53 7 13 1284.82 13.53 7 13 473 51.2 5.05 HVO_0989 conserved hypothetical protein 13.49 1 2 2 4 2.717E7 0.00 13.49 2 2 202.09 13.49 2 2 126 14.4 4.81 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 13.49 1 4 4 11 2.712E7 8.00 13.49 4 6 461.65 10.05 3 5 378 39.8 4.45 HVO_0769 TRAM domain protein 13.43 1 2 2 6 1.403E7 6.05 13.43 2 3 389.36 13.43 2 3 134 14.8 4.32 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 13.42 1 3 3 6 2.797E7 2.18 9.87 2 3 269.08 6.84 2 3 395 42.4 4.54 HVO_1698 CBS/parB domain protein 13.21 1 2 3 11 5.243E7 6.95 13.21 3 5 576.60 13.21 3 6 265 29.4 4.92 HVO_1375 O-succinylbenzoic acid--CoA ligase 13.19 1 4 4 9 2.178E7 11.52 7.33 3 4 502.12 13.19 4 5 614 64.7 4.28 HVO_B0256 aldehyde ferredoxin oxidoreductase 13.15 1 5 5 17 2.469E7 15.03 13.15 5 8 915.88 13.15 5 9 555 59.9 4.55 HVO_0180 23S rRNA (uridine-2'-O-) methyltransferase 13.13 1 2 2 4 2.524E7 2.61 13.13 2 2 233.01 13.13 2 2 259 28.3 4.70 HVO_0541 aconitate hydratase 13.11 1 9 9 31 6.113E7 15.26 12.05 8 14 1698.16 13.11 9 17 938 102.1 4.40 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 13.06 1 3 3 9 1.594E7 6.91 8.21 2 4 603.42 13.06 3 5 268 27.9 4.87 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 13.05 1 4 5 15 3.458E7 10.80 13.05 5 7 776.98 13.05 5 8 383 42.0 4.49 HVO_1648 adenylate cyclase 12.97 1 2 2 6 4.433E6 4.30 12.97 2 3 301.72 12.97 2 3 185 20.5 4.34 HVO_B0066 Lrp/AsnC family transcription regulator 12.80 1 2 2 8 1.581E7 9.41 12.80 2 4 407.87 12.80 2 4 164 18.5 4.41 HVO_B0114 IclR family transcription regulator 12.70 1 3 3 4 6.896E6 2.39 8.73 2 2 132.98 8.73 2 2 252 28.4 5.44 HVO_B0001 Orc1-type DNA replication protein 12.68 1 4 5 14 2.866E7 3.54 9.02 4 5 780.52 12.68 5 9 410 45.8 5.33 HVO_C0077 sarcosine oxidase 12.66 1 3 3 12 1.936E7 12.31 12.66 3 6 960.59 12.66 3 6 387 42.9 4.70 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 12.60 1 3 3 10 3.719E7 12.54 12.60 3 5 681.17 12.60 3 5 365 39.0 4.61 HVO_1058 TrkA domain protein 12.58 1 5 5 15 5.525E7 15.84 10.34 4 7 862.11 12.58 5 8 445 47.7 4.35 HVO_0056 conserved hypothetical protein 12.50 1 2 2 2 1.473E7 198.65 12.50 2 2 192 20.9 4.16 HVO_1446 "fructose-1,6-bisphosphatase" 12.46 1 2 2 4 5.894E6 589.00 12.46 2 4 297 31.6 4.45 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 12.44 1 4 4 10 1.159E7 9.28 12.44 4 5 563.94 12.44 4 5 386 40.0 4.68 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 12.41 1 3 3 10 2.933E7 6.65 12.41 3 5 551.68 12.41 3 5 266 29.7 4.32 HVO_0322 MinD/ParA domain protein 12.39 1 4 4 13 8.350E7 15.87 12.39 4 6 762.43 12.39 4 7 581 58.8 3.70 HVO_2256 DUF262 family protein 12.34 1 6 6 18 6.701E7 17.91 12.34 6 9 1059.07 12.34 6 9 462 54.9 4.89 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 12.32 1 3 4 13 2.580E7 12.24 12.32 4 7 605.73 9.85 3 6 406 45.5 5.08 HVO_1925 probable GTP-binding protein 12.31 1 3 3 11 2.916E7 1.61 12.31 3 6 325.31 12.31 3 5 325 36.5 4.72 HVO_3000 DNA ligase (NAD) 12.30 1 6 6 19 1.445E8 14.37 10.30 5 9 976.24 12.30 6 10 699 75.8 4.50 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 12.28 1 5 5 11 4.049E7 5.83 10.99 4 5 617.87 12.28 5 6 464 53.1 4.54 HVO_B0382 TATA-binding transcription initiation factor 12.23 1 2 2 5 1.657E7 0.00 12.23 2 2 211.66 12.23 2 3 188 20.1 4.12 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 12.17 1 8 8 24 4.147E7 18.02 10.62 7 12 1258.79 12.17 8 12 838 89.1 4.65 HVO_1625 conserved hypothetical protein 11.93 1 6 6 21 3.550E7 20.98 10.86 5 10 1512.26 11.93 6 11 654 70.1 4.04 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 11.91 1 4 4 10 2.130E7 7.64 9.68 3 5 456.50 7.69 3 5 403 41.1 4.73 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 11.86 1 4 4 15 2.476E7 11.46 11.86 4 8 782.22 11.86 4 7 388 41.9 4.35 HVO_1711 glucoamylase 11.85 1 15 15 50 3.857E7 37.78 11.85 15 25 2809.07 11.85 15 25 1511 166.1 4.64 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 11.81 1 0 6 24 1.893E8 18.52 11.81 6 12 1116.73 11.81 6 12 432 48.1 5.02 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 11.80 1 4 4 13 8.088E7 11.20 11.80 4 7 940.00 10.03 3 6 339 38.1 4.50 HVO_2891 thymidine kinase 11.79 1 2 2 6 8.335E6 2.31 11.79 2 3 357.13 11.79 2 3 195 21.4 4.63 HVO_0228 ParA domain protein 11.74 1 2 2 3 7.477E7 415.49 11.74 2 3 247 24.6 4.16 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 11.70 1 5 5 14 3.618E7 17.35 11.70 5 7 919.24 11.70 5 7 658 72.1 4.70 HVO_0733 transcription initiation factor TFB 11.66 1 1 4 13 1.614E8 16.78 11.66 4 7 818.10 8.59 3 6 326 37.2 6.00 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 8 1.095E8 2.98 11.64 2 4 349.40 11.64 2 4 189 20.3 4.22 HVO_1150 IS200-type transposase 11.54 1 2 2 8 1.307E7 4.86 11.54 2 4 461.38 11.54 2 4 130 14.7 5.49 HVO_0001 Orc1-type DNA replication protein 11.52 1 5 6 22 1.819E7 13.32 11.52 6 10 1170.78 11.52 6 12 564 62.1 4.39 HVO_1723 DNA repair helicase Rad25 11.51 1 8 8 20 2.850E7 16.59 11.51 8 10 1230.09 11.51 8 10 695 76.8 4.69 HVO_1629 conserved hypothetical protein 11.49 1 4 4 12 2.611E7 9.49 11.49 4 6 549.74 11.49 4 6 531 56.3 4.69 HVO_B0200 malate synthase 11.47 1 3 3 11 4.564E7 13.45 11.47 3 6 764.09 11.47 3 5 436 48.3 4.30 HVO_1861 thiamine-monophosphate kinase 11.45 1 3 3 10 1.453E7 7.53 11.45 3 5 524.71 11.45 3 5 297 30.8 4.32 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 11.39 1 2 2 6 4.319E7 5.43 11.39 2 3 343.37 11.39 2 3 237 25.4 4.46 HVO_1098 diaminopimelate decarboxylase 11.33 1 4 4 14 6.842E7 9.09 11.33 4 7 534.00 11.33 4 7 415 44.4 5.02 HVO_1129 conserved hypothetical protein 11.28 1 3 3 9 4.178E7 11.70 10.00 2 4 593.32 11.28 3 5 390 43.0 4.44 HVO_2561 50S ribosomal protein L2 11.20 1 2 2 4 1.706E7 0.00 11.20 2 2 121.95 11.20 2 2 241 25.6 10.40 HVO_2918 thymidylate synthase 11.14 1 2 2 6 2.629E7 4.56 11.14 2 3 265.82 11.14 2 3 332 37.5 4.61 HVO_0220 ATP-dependent DNA helicase MCM 11.11 1 8 8 23 2.519E7 9.56 11.11 8 12 942.66 11.11 8 11 702 78.8 4.73 HVO_B0057 precorrin-3B C17-methyltransferase 11.05 1 2 2 10 1.141E8 11.82 11.05 2 5 776.54 11.05 2 5 344 36.3 4.31 HVO_2707 GFO family oxidoreductase 11.02 1 4 4 14 1.002E8 15.10 11.02 4 7 1075.85 11.02 4 7 372 41.0 4.55 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 11.00 1 3 3 8 3.439E7 0.00 11.00 3 4 229.20 11.00 3 4 482 50.6 4.31 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 10.97 1 3 3 10 1.285E7 10.47 10.97 3 5 679.70 10.97 3 5 383 41.9 4.21 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 10.96 1 5 5 20 2.215E7 10.85 10.96 5 10 1051.48 10.96 5 10 584 63.3 4.79 HVO_0868 NAD-dependent epimerase/dehydratase 10.94 1 4 4 11 2.969E7 6.09 10.94 4 5 720.48 10.94 4 6 329 36.1 4.55 HVO_1565 DNA ligase (ATP) 10.94 1 6 6 18 9.807E6 12.49 10.94 6 9 884.33 10.94 6 9 585 62.7 4.44 HVO_1503 3-isopropylmalate dehydratase small subunit 10.89 1 2 2 10 9.583E7 4.00 10.89 2 5 393.86 10.89 2 5 202 22.0 4.15 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 10.88 1 3 4 10 7.275E6 10.47 10.88 4 5 437.62 10.88 4 5 386 41.3 4.46 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 10.83 1 2 2 8 6.556E7 10.15 10.83 2 4 631.16 10.83 2 4 277 30.6 4.30 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 10.76 1 4 4 7 1.888E7 1.88 10.76 4 4 172.23 7.87 3 3 381 40.5 4.51 HVO_1179 homolog to NAD kinase 10.73 1 2 2 4 1.063E8 0.00 10.73 2 2 118.08 10.73 2 2 354 36.7 4.60 HVO_1581 cytidine deaminase 10.71 1 2 2 2 1.218E7 167.75 10.71 2 2 140 15.0 4.22 HVO_B0324 conserved hypothetical protein 10.69 1 4 4 14 2.597E7 14.21 10.69 4 7 854.35 10.69 4 7 449 48.0 4.58 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 10.55 1 2 2 6 1.110E7 2.26 10.55 2 3 145.21 10.55 2 3 237 26.2 4.70 HVO_0818 threonine synthase 10.54 1 4 4 19 1.039E8 4.66 10.54 4 10 942.97 10.54 4 9 389 40.8 4.31 HVO_0854 DNA double-strand break repair ATPase Rad50 10.53 1 10 10 25 1.518E8 15.57 9.74 9 12 1243.22 10.53 10 13 893 100.0 4.58 HVO_A0254 DUF234 domain protein 10.41 1 6 6 11 1.408E7 2.77 5.86 3 4 515.29 10.41 6 7 461 52.7 4.78 HVO_2702 alpha/beta hydrolase fold protein 10.38 1 2 2 8 2.534E7 4.98 10.38 2 4 416.06 10.38 2 4 260 28.0 4.53 HVO_1685 conserved hypothetical protein 10.37 1 5 5 14 2.141E7 6.95 10.37 5 7 561.14 10.37 5 7 492 54.5 5.74 HVO_2761 mevalonate kinase 10.35 1 2 2 2 3.510E7 2.81 10.35 2 2 367 38.2 4.31 HVO_0826 peptidase M42 family protein 10.34 1 3 3 14 2.136E7 15.04 10.34 3 7 949.20 10.34 3 7 348 37.7 4.54 HVO_2158 malic enzyme (NADP) 10.25 1 1 4 15 6.899E7 14.15 10.25 4 8 781.90 8.52 3 7 751 81.4 4.55 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 10.23 1 4 4 12 1.116E8 11.00 10.23 4 6 732.59 10.23 4 6 430 44.2 4.37 HVO_2507 Lrp/AsnC family transcription regulator 10.22 1 2 2 4 1.310E7 1.66 10.22 2 2 96.52 10.22 2 2 137 15.5 4.67 HVO_0670 glutathione S-transferase 10.12 1 3 3 8 1.449E7 5.96 10.12 3 4 489.34 10.12 3 4 326 38.1 4.56 21961227 Keratin 6B [Homo sapiens] 10.11 1 0 7 33 1.707E8 24.55 10.11 7 17 1986.82 10.11 7 16 564 60.0 8.00 HVO_1228 halocyanin 10.11 1 7 7 23 2.985E7 11.45 8.04 6 11 1212.18 10.11 7 12 821 83.7 4.17 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 10.09 1 2 2 4 1.624E7 0.00 10.09 2 2 146.84 10.09 2 2 327 36.2 4.63 HVO_1937 "probable 5,10-methylenetetrahydrofolate reductase" 10.06 1 2 2 4 1.524E7 4.69 10.06 2 2 203.79 10.06 2 2 328 34.5 4.63 HVO_0760 "probable glycosyltransferase, type 2" 10.05 1 3 3 10 1.537E7 7.51 10.05 3 5 538.34 10.05 3 5 368 40.7 4.82 4557890 keratin 5 [Homo sapiens] 10.00 1 0 7 34 1.523E8 32.37 10.00 7 17 2143.76 10.00 7 17 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 10.00 1 0 7 34 1.523E8 32.37 10.00 7 17 2143.76 10.00 7 17 590 62.4 8.06 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 4 3.518E7 4.91 10.00 2 4 190 21.0 4.74 HVO_2565 conserved hypothetical protein 10.00 1 2 2 2 8.434E6 0.00 10.00 2 2 280 30.3 4.70 HVO_0719 transcription elongation factor Spt5/NusG 10.00 1 2 2 3 1.949E7 286.00 10.00 2 3 150 16.3 4.50 HVO_2160 conserved hypothetical protein 9.92 1 15 15 73 1.672E8 94.32 9.92 15 36 5923.18 9.92 15 37 2257 232.7 3.92 HVO_2998 homoserine O-acetyltransferase 9.88 1 3 3 10 1.943E7 3.81 9.88 3 5 421.36 9.88 3 5 415 44.8 4.69 HVO_3014 origin-associated GTP-binding protein OapA 9.86 1 2 2 8 3.269E7 5.64 9.86 2 4 386.40 9.86 2 4 213 24.0 5.01 HVO_2906 tRNA (cytidine/uridine-2'-O-)-methyltransferase 9.82 1 2 2 4 1.360E7 3.74 9.82 2 2 217.45 9.82 2 2 275 30.6 4.58 HVO_B0127 oxidoreductase (luciferase family protein) 9.78 1 2 2 6 1.538E7 6.24 9.78 2 3 168.58 9.78 2 3 317 35.7 4.60 HVO_0019 probable S-adenosylmethionine-dependent methyltransferase (homolog to 24-sterol C-methyltransferase) 9.73 1 2 2 3 7.727E6 326.84 9.73 2 3 226 25.6 4.64 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 9.71 1 2 2 4 1.274E7 4.25 9.71 2 2 144.03 9.71 2 2 175 18.8 4.63 HVO_0848 endonuclease III 9.69 1 2 2 6 9.520E6 3.71 9.69 2 3 266.97 9.69 2 3 227 25.5 4.55 HVO_A0458 ParA domain protein 9.62 1 2 2 8 3.069E7 8.79 9.62 2 4 383.59 9.62 2 4 291 32.2 4.79 HVO_1936 F420-0:gamma-glutamyl ligase 9.56 1 2 2 6 1.743E7 7.02 9.56 2 3 366.64 9.56 2 3 251 27.4 4.68 HVO_A0452 UspA domain protein 9.56 1 2 2 6 7.578E6 5.61 9.56 2 3 435.37 9.56 2 3 293 31.3 4.63 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 9.53 1 5 5 15 2.595E7 6.19 9.53 5 8 536.55 9.53 5 7 661 71.0 4.35 HVO_0639 AAA-type ATPase (MoxR subfamily) 9.49 1 3 3 11 2.275E7 1.71 6.96 2 5 451.27 9.49 3 6 316 34.7 4.89 HVO_A0586 sugar nucleotidyltransferase 9.49 1 3 3 10 2.037E7 8.07 9.49 3 5 478.71 9.49 3 5 411 43.7 4.69 HVO_1995 conserved hypothetical protein 9.47 1 2 2 6 8.507E6 4.49 9.47 2 3 314.53 9.47 2 3 243 26.5 4.39 HVO_0190 TIGR00268 family protein 9.40 1 2 2 7 1.443E7 0.00 9.40 2 3 196.73 9.40 2 4 298 32.5 4.60 HVO_1593 PAC2 family protein 9.27 1 2 2 2 4.233E6 179.77 9.27 2 2 248 26.6 4.46 HVO_0558 SAMP-activating enzyme E1 9.26 1 2 2 6 1.846E7 4.30 9.26 2 3 436.92 9.26 2 3 270 28.7 4.35 HVO_2080 conserved hypothetical protein 9.26 1 3 3 9 8.646E6 6.33 9.26 3 4 378.88 9.26 3 5 540 57.0 4.30 HVO_1895 KEOPS complex subunit Kae1/Bud32 9.24 1 3 3 14 2.071E7 23.00 9.24 3 7 1124.10 9.24 3 7 552 59.0 5.07 HVO_1079 sulfate adenylyltransferase small subunit 9.23 1 3 3 10 9.602E7 13.53 9.23 3 5 740.00 9.23 3 5 325 37.5 4.18 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 9.15 1 2 2 8 2.912E7 12.06 9.15 2 4 524.69 9.15 2 4 328 36.1 4.67 HVO_0572 lipoate-protein ligase 9.09 1 2 2 12 1.305E7 8.22 9.09 2 6 792.86 9.09 2 6 275 30.5 4.84 HVO_0894 acyl-CoA synthetase 9.06 1 1 4 11 2.520E7 13.16 9.06 4 6 630.63 6.95 3 5 662 74.3 4.48 HVO_1323 "shikimate kinase, archaeal-type" 9.00 1 2 2 12 6.387E7 8.84 9.00 2 6 658.40 9.00 2 6 289 29.5 4.30 HVO_2860 conserved hypothetical protein 8.90 1 4 4 10 1.210E7 9.02 5.52 3 5 545.89 8.90 4 5 562 58.9 4.49 HVO_2187 CHP01210 family protein 8.89 1 2 2 2 1.961E7 2.30 8.89 2 2 360 40.0 4.58 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 8.85 1 0 4 23 1.198E8 15.59 8.85 4 12 1444.32 8.85 4 11 384 42.4 5.40 HVO_0017 conserved hypothetical protein 8.85 1 2 2 7 4.115E7 0.00 8.85 2 4 236.23 8.85 2 3 192 21.9 4.50 HVO_1553 hydroxypyruvate reductase 8.82 1 4 4 12 1.869E7 2.03 8.82 4 6 507.92 6.56 3 6 442 45.2 4.50 HVO_0014 ATP-dependent DNA helicase Hel308a 8.71 1 6 6 15 2.257E7 6.19 8.71 6 8 604.70 6.05 5 7 827 90.3 4.67 HVO_2908 dihydropteroate synthase 8.71 1 2 2 6 4.689E7 7.04 8.71 2 3 387.90 8.71 2 3 379 40.8 4.53 HVO_A0035 "FtsZ family protein, type III" 8.63 1 1 2 2 2.864E8 80.93 8.63 2 2 394 41.1 4.81 HVO_A0551 acyl-CoA synthetase 8.36 1 4 4 13 1.744E7 9.75 8.36 4 7 695.44 8.36 4 6 538 59.6 4.65 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 8.33 1 0 6 29 1.523E8 19.56 8.33 6 15 1664.79 8.33 6 14 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 8.33 1 0 6 29 1.523E8 19.56 8.33 6 15 1664.79 8.33 6 14 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 8.33 1 0 6 29 1.523E8 19.56 8.33 6 15 1664.79 8.33 6 14 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 8.33 1 0 6 29 1.523E8 19.56 8.33 6 15 1664.79 8.33 6 14 564 60.0 7.72 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 8.31 1 10 10 28 3.490E7 14.31 7.94 9 12 1346.46 8.31 10 16 1335 150.5 4.60 HVO_1354 DNA mismatch repair protein MutS 8.28 1 4 4 14 2.181E7 7.81 8.28 4 7 537.48 8.28 4 7 580 62.1 4.56 HVO_1716 7-cyano-7-deazaguanine synthase 8.20 1 2 2 5 2.989E7 1.90 8.20 2 3 108.20 8.20 2 2 244 26.8 4.42 HVO_C0054 hypothetical protein 8.14 1 2 2 6 1.642E7 6.07 8.14 2 3 363.17 8.14 2 3 344 37.5 4.70 HVO_0179 Lrp/AsnC family transcription regulator / TrkA domain protein 8.05 1 2 2 2 7.491E6 2.53 8.05 2 2 261 28.0 4.58 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 8.04 1 3 3 9 5.560E7 12.04 8.04 3 5 573.37 5.28 2 4 398 43.4 4.37 HVO_2923 proteasome alpha subunit 8.03 1 1 2 6 2.103E8 6.98 8.03 2 3 442.98 8.03 2 3 249 26.7 4.39 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 8.00 1 0 4 18 1.893E8 14.12 8.00 4 9 813.41 8.00 4 9 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 8.00 1 0 4 18 1.893E8 14.12 8.00 4 9 813.41 8.00 4 9 400 44.1 5.14 HVO_2430 ABC-type transport system ATP-binding protein (probable substrate glutamine) 7.85 1 2 2 2 1.575E8 0.00 7.85 2 2 242 26.6 4.88 HVO_2614 uridine phosphorylase 7.85 1 2 2 13 4.008E8 10.60 7.85 2 6 769.53 7.85 2 7 242 25.8 4.30 HVO_2321 bacterial-type DNA primase DnaG 7.84 1 4 4 9 2.365E7 4.57 6.36 3 4 507.42 7.84 4 5 472 49.4 4.36 HVO_1656 YyaL family protein 7.82 1 6 6 17 1.000E7 8.87 6.97 5 8 738.70 7.82 6 9 703 77.3 4.49 HVO_0968 NADH dehydrogenase-like complex subunit CD 7.80 1 0 4 16 1.147E8 14.42 7.80 4 8 992.89 7.80 4 8 564 63.3 4.60 HVO_2227 siroheme decarboxylase AhbA 7.78 1 2 2 6 2.971E7 9.14 7.78 2 3 534.50 7.78 2 3 347 39.1 4.69 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 7.72 1 3 3 8 1.483E7 1.69 7.72 3 4 279.20 7.72 3 4 337 35.9 4.39 HVO_B0182 deoxyhypusine synthase 7.72 1 2 2 8 5.313E7 5.54 7.72 2 4 491.40 7.72 2 4 324 35.6 4.30 HVO_A0150 TrmB family transcription regulator 7.63 1 3 3 10 4.735E7 3.71 7.63 3 5 505.91 7.63 3 5 354 39.0 4.63 HVO_A0257 Orc1-type DNA replication protein 7.53 1 3 3 8 5.854E6 7.32 7.53 3 4 515.94 7.53 3 4 425 48.0 4.94 HVO_B0052 PQQ repeat protein 7.52 1 3 3 7 1.427E7 6.41 5.10 2 3 453.49 7.52 3 4 412 44.1 5.48 HVO_A0547 DUF1028 family protein 7.51 1 3 3 7 1.289E7 2.84 7.51 3 4 353.43 7.51 2 3 333 35.2 4.16 HVO_2628 GHMP family kinase (homolog to beta-ribofuranosylaminobenzene 5'-phosphate synthase) 7.50 1 2 2 4 7.835E6 4.01 7.50 2 2 237.98 7.50 2 2 320 33.5 5.27 HVO_B0375 Spo0M family protein 7.35 1 2 2 4 7.753E6 2.36 7.35 2 2 213.84 7.35 2 2 245 27.2 4.35 HVO_1169 "probable glycosyltransferase, type 1" 7.34 1 3 3 5 6.085E6 0.00 5.43 2 2 216.58 7.34 3 3 368 40.8 4.73 HVO_2004 serine O-acetyltransferase 7.32 1 1 2 9 1.948E8 2.53 7.32 2 4 448.88 7.32 2 5 287 31.9 5.21 HVO_2697 DNA primase small subunit 7.27 1 2 2 6 7.437E6 5.00 7.27 2 3 342.70 7.27 2 3 385 42.6 4.72 HVO_1139 squalene synthase 7.26 1 2 2 8 3.452E7 5.25 7.26 2 4 350.33 7.26 2 4 358 39.7 4.54 HVO_0135 RIO-type serine/threonine protein kinase 7.24 1 2 2 6 9.267E6 6.76 7.24 2 3 406.37 7.24 2 3 290 33.0 4.81 HVO_2421 probable DNA-binding protein 7.23 1 2 2 2 1.155E7 116.57 7.23 2 2 235 25.8 4.89 HVO_1357 receiver/bat box HTH-10 family transcription regulator 7.22 1 3 3 8 1.447E7 4.55 7.22 3 4 335.74 7.22 3 4 582 62.7 4.40 HVO_2311 glutamyl-tRNA reductase 7.16 1 2 2 6 1.272E7 3.44 7.16 2 3 330.70 7.16 2 3 461 49.2 4.54 HVO_1047 NADPH:quinone reductase 7.12 1 2 2 8 1.030E7 6.13 7.12 2 4 365.78 7.12 2 4 323 33.8 4.27 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 6 4.038E7 7.17 7.07 2 3 471.88 7.07 2 3 297 32.3 3.98 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 7.02 1 0 4 18 1.893E8 14.12 7.02 4 9 813.41 7.02 4 9 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 7.02 1 0 4 18 1.893E8 14.12 7.02 4 9 813.41 7.02 4 9 456 49.2 4.77 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 7.00 1 2 2 3 1.172E7 2.76 7.00 2 3 400 44.2 4.32 HVO_1309 peptidase M24 family protein 6.91 1 3 3 9 3.578E7 3.64 3.58 2 4 411.37 6.91 3 5 391 42.1 4.36 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 6.81 1 2 2 5 1.025E7 5.07 6.81 2 2 222.70 6.81 2 3 323 34.9 5.24 HVO_2071 conserved hypothetical protein 6.74 1 3 3 8 1.565E7 7.77 6.74 3 4 485.56 6.74 3 4 549 58.4 4.72 HVO_2108 IclR family transcription regulator 6.72 1 2 2 2 9.248E6 0.00 6.72 2 2 253 28.0 5.74 HVO_2381 UPF0272 family protein 6.69 1 3 3 7 1.647E7 7.16 4.67 2 3 491.44 6.69 3 4 493 52.3 4.88 HVO_1419 HTH-10 family transcription regulator 6.67 1 2 2 6 1.306E7 4.60 6.67 2 3 219.69 6.67 2 3 225 25.2 4.77 HVO_0304 electron transfer flavoprotein alpha subunit 6.62 1 2 2 5 4.681E7 689.35 6.62 2 5 317 33.5 4.18 386849 keratin type II 6.57 1 0 4 13 1.118E8 10.32 6.57 4 7 758.30 6.57 4 6 563 59.9 7.94 HVO_2932 GTP-binding protein 6.57 1 2 2 6 3.552E7 5.10 6.57 2 3 358.81 6.57 2 3 396 43.5 4.51 HVO_0824 "probable glycosyltransferase, type 1" 6.53 1 2 2 8 8.475E6 7.25 6.53 2 4 504.73 6.53 2 4 352 39.6 5.08 HVO_2183 aldehyde ferredoxin oxidoreductase 6.53 1 3 3 7 2.671E6 6.33 4.20 2 3 366.96 6.53 3 4 643 69.3 4.59 HVO_1864 molybdopterin synthase catalytic subunit 6.51 1 2 2 8 2.269E7 1.90 6.51 2 4 323.68 6.51 2 4 261 27.9 4.41 HVO_A0093 IclR family transcription regulator 6.50 1 2 2 6 6.936E6 0.00 6.50 2 3 141.11 6.50 2 3 246 27.5 5.15 HVO_2873 flap endonuclease Fen1 6.44 1 2 2 7 1.866E7 5.01 6.44 2 4 380.30 6.44 2 3 326 36.4 4.40 HVO_0431 HAD superfamily hydrolase 6.34 1 2 2 8 1.750E7 2.02 6.34 2 4 318.03 6.34 2 4 284 30.4 4.26 HVO_B0143 receiver/sensor box histidine kinase 6.20 1 3 3 8 1.734E7 8.49 6.20 3 4 621.95 6.20 3 4 597 66.0 4.41 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 6.08 1 2 3 7 5.158E7 2.05 6.08 3 3 329.06 6.08 3 4 444 47.1 4.77 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 6.08 1 5 5 13 9.305E6 8.79 5.27 4 6 625.80 6.08 5 7 740 85.6 4.70 HVO_0029 UvrABC system protein B 6.02 1 4 4 8 2.056E7 1.82 6.02 4 4 294.49 6.02 4 4 698 79.0 4.45 HVO_2350 YyaL family protein 5.98 1 3 3 7 2.058E7 1.69 5.07 2 3 273.34 5.98 3 4 552 58.8 4.59 HVO_2302 ubiquinone biosynthesis protein UbiB 5.91 1 1 2 2 4.492E5 0.00 5.91 2 2 558 63.0 4.69 HVO_B0054 sirohydrochlorin cobaltochelatase 5.91 1 2 2 2 5.613E6 94.85 5.91 2 2 406 44.1 4.72 HVO_A0550 receiver/sensor box histidine kinase 5.88 1 4 4 10 1.251E7 8.07 5.88 4 5 511.45 5.88 4 5 885 95.9 4.46 HVO_C0042 helicase domain protein 5.81 1 6 6 18 2.077E7 11.04 5.81 6 9 858.41 5.81 6 9 1274 144.4 4.67 HVO_1425 conserved hypothetical protein 5.66 1 2 2 7 1.601E7 1.71 5.66 2 3 335.79 5.66 2 4 265 30.4 4.61 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 5.66 1 2 2 6 1.328E7 6.87 5.66 2 3 397.73 5.66 2 3 265 28.7 4.87 HVO_1812 conserved hypothetical protein 5.60 1 2 2 6 2.037E7 5.70 5.60 2 3 302.53 5.60 2 3 375 40.5 4.50 HVO_1681 DNA N-glycosylase 5.59 1 2 2 6 8.480E6 4.23 5.59 2 3 423.13 5.59 2 3 304 34.2 4.63 HVO_A0156 acyl-CoA synthetase 5.57 1 0 3 9 2.520E7 10.18 5.57 3 5 479.99 3.46 2 4 664 74.0 4.40 HVO_2229 flavin-containing amine-oxidoreductase 5.52 1 2 2 4 1.500E7 3.05 5.52 2 2 127.00 5.52 2 2 344 37.9 4.92 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 5.47 1 2 2 6 1.658E7 8.27 5.47 2 3 520.24 5.47 2 3 475 49.3 4.49 HVO_1052 transcription initiation factor TFB 5.42 1 0 2 8 5.796E7 5.26 5.42 2 4 399.62 5.42 2 4 332 37.3 5.25 HVO_2605 MiaB-like tRNA modifying enzyme 5.36 1 2 2 8 9.031E6 4.26 5.36 2 4 272.50 5.36 2 4 429 47.4 5.03 HVO_A0328 2-keto-3-deoxygluconate kinase 5.35 1 1 2 4 1.239E8 0.00 5.35 2 2 160.46 5.35 2 2 318 34.0 4.60 HVO_0580 putative tRNA 2-thiolation protein 5.30 1 2 2 4 9.622E6 4.58 5.30 2 2 237.15 5.30 2 2 321 36.1 5.01 HVO_B0233 alpha-L-arabinofuranosidase 5.28 1 2 2 4 1.966E7 2.63 5.28 2 2 221.49 5.28 2 2 511 57.5 4.39 31074633 keratin 6L [Homo sapiens] 5.23 1 0 3 12 1.181E8 12.31 5.23 3 6 883.88 5.23 3 6 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 5.23 1 0 3 12 1.181E8 12.31 5.23 3 6 883.88 5.23 3 6 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 5.23 1 0 3 12 1.181E8 12.31 5.23 3 6 883.88 5.23 3 6 535 57.7 7.20 HVO_1683 4-alpha-glucanotransferase 5.04 1 3 3 8 2.352E7 4.33 5.04 3 4 415.77 5.04 3 4 496 56.3 4.45 HVO_0687 M20 family amidohydrolase 4.95 1 2 2 4 1.815E7 4.91 4.95 2 2 311.46 4.95 2 2 444 47.5 4.58 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 4.89 1 3 3 10 1.506E7 6.26 4.89 3 5 367.46 4.89 3 5 573 62.9 4.45 HVO_1735 conserved hypothetical protein 4.85 1 3 3 6 1.659E6 4.13 4.85 3 3 288.64 4.85 3 3 660 75.7 4.50 HVO_1340 "probable glycosyltransferase, type 1" 4.80 1 2 2 2 3.451E7 3.66 4.80 2 2 375 41.0 4.42 HVO_2880 probable peptide chain release factor pelota 4.78 1 2 2 6 4.660E7 4.94 4.78 2 3 351.12 4.78 2 3 356 39.3 4.63 HVO_C0057 Orc1-type DNA replication protein 4.78 1 2 2 8 1.658E7 8.75 4.78 2 4 489.56 4.78 2 4 418 46.3 5.02 4504911 keratin 13 isoform b [Homo sapiens] 4.76 1 0 2 9 1.184E8 8.13 4.76 2 5 457.06 4.76 2 4 420 45.8 4.88 HVO_1374 acyl-CoA synthetase 4.70 1 2 2 3 2.456E7 501.79 4.70 2 3 553 61.1 4.50 31074631 keratin 1b [Homo sapiens] 4.67 1 0 3 16 1.454E8 12.73 4.67 3 8 998.66 4.67 3 8 578 61.8 5.97 HVO_B0038A D-xylonate dehydratase 4.61 1 0 2 16 1.493E8 12.82 4.61 2 8 828.35 4.61 2 8 412 45.5 4.55 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 4.53 1 2 2 6 4.385E7 2.28 4.53 2 3 291.54 4.53 2 3 353 36.7 4.65 HVO_1413 probable NADH dehydrogenase 4.51 1 2 2 4 1.230E7 4.25 4.51 2 2 235.62 4.51 2 2 377 39.7 4.67 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 4.39 1 2 2 3 7.675E6 241.89 4.39 2 3 410 46.0 4.89 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 4.37 1 0 2 9 1.184E8 8.13 4.37 2 5 457.06 4.37 2 4 458 49.6 4.96 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 4.34 1 2 2 8 3.446E7 6.24 4.34 2 4 368.51 4.34 2 4 438 46.4 4.58 HVO_0689 chromosome segregation protein Smc 4.27 1 5 5 10 2.643E7 6.43 2.34 3 4 591.69 4.27 5 6 1240 138.1 4.39 HVO_0073 single-stranded-DNA-specific exonuclease RecJ1 4.20 1 2 2 2 6.527E6 125.06 4.20 2 2 476 50.6 4.68 HVO_2369 conserved hypothetical protein 4.01 1 2 2 3 4.901E6 151.54 4.01 2 3 424 47.3 5.06 18031720 keratin protein K6irs [Homo sapiens] 3.73 1 0 2 10 7.655E7 9.75 3.73 2 5 580.87 3.73 2 5 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 3.72 1 0 2 10 7.655E7 9.75 3.72 2 5 580.87 3.72 2 5 511 55.8 6.89 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 3.66 1 2 2 4 1.232E7 2.02 3.66 2 2 157.14 3.66 2 2 437 47.1 4.72 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 10 7.655E7 9.75 3.63 2 5 580.87 3.63 2 5 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.59 1 0 2 10 7.655E7 9.75 3.59 2 5 580.87 3.59 2 5 529 57.8 7.71 4504919 keratin 8 [Homo sapiens] 3.52 1 0 3 20 9.495E7 13.20 3.52 3 10 1080.35 3.52 3 10 483 53.7 5.59 28173564 keratin 6 irs3 [Homo sapiens] 3.52 1 0 2 10 7.655E7 9.75 3.52 2 5 580.87 3.52 2 5 540 58.9 7.23 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 10 1.385E8 7.07 3.45 2 5 349.57 3.45 2 5 464 50.6 5.47 HVO_B0154 receiver/sensor box histidine kinase 3.38 1 4 4 11 2.021E7 12.18 3.38 4 6 573.89 3.38 4 5 1301 144.1 4.39 HVO_1113 "FtsZ family protein, type III" 3.34 1 0 2 6 2.737E8 3.24 3.34 2 3 328.51 3.34 2 3 389 40.8 4.89 HVO_2955 DEAD/DEAH box helicase 3.34 1 3 3 6 1.516E7 1.61 3.34 3 3 214.85 3.34 3 3 779 85.8 4.94 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 3.26 1 3 3 10 1.435E7 3.85 3.26 3 5 397.02 3.26 3 5 858 93.9 4.69 HVO_0065 DNA-directed DNA polymerase D large subunit 3.24 1 2 2 4 1.562E7 2.10 3.24 2 2 112.47 3.24 2 2 1202 133.9 4.60 HVO_C0043 conserved hypothetical protein 3.18 1 2 2 2 1.098E7 136.55 3.18 2 2 661 73.8 4.75 HVO_A0001 Orc1-type DNA replication protein 3.13 1 2 2 2 7.571E6 0.00 3.13 2 2 416 47.0 4.97 HVO_0069 sulfatase 3.11 1 2 2 4 1.682E7 0.00 3.11 2 2 180.41 3.11 2 2 515 57.4 4.35 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 2.96 1 2 2 4 1.325E7 343.87 2.96 2 4 439 47.2 4.59 HVO_2888 homolog to elongator complex protein ELP3 2.91 1 2 2 3 1.761E7 1.65 2.91 2 3 550 62.6 5.01 HVO_2736 tRNA(Met) cytidine acetyltransferase 2.65 1 2 2 4 7.727E6 0.00 2.65 2 2 228.56 2.65 2 2 754 81.2 4.96 66774007 "Keratin, type II cytoskeletal 1b" 2.60 1 0 2 12 7.729E7 6.02 2.60 2 6 584.26 2.60 2 6 576 61.7 5.85 HVO_A0064 Orc1-type DNA replication protein 2.40 1 1 2 4 1.658E7 350.36 2.40 2 4 499 55.5 4.91