Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0359 translation elongation factor aEF-1 alpha subunit 80.52 1 22 26 935 3.339E10 882.09 76.25 25 437 68882.84 80.52 26 498 421 45.7 4.73 HVO_0880 conserved hypothetical protein 79.80 1 33 34 382 2.452E9 389.91 78.50 33 190 25404.83 79.80 33 192 307 36.3 4.74 HVO_0356 translation elongation factor aEF-2 78.54 1 49 49 805 1.176E10 822.12 76.89 47 402 52031.29 78.54 49 403 727 80.4 4.73 HVO_1454 aspartate carbamoyltransferase catalytic subunit 75.66 1 14 14 69 5.678E8 68.69 62.50 13 34 4492.06 75.66 14 35 304 33.7 4.92 HVO_1507 acetolactate synthase small subunit 73.85 1 12 12 54 3.325E8 45.79 73.85 11 26 3590.21 73.85 12 28 218 23.7 4.94 HVO_2900 fumarate hydratase 71.43 1 21 21 145 2.269E9 156.72 63.75 20 74 9494.18 71.43 21 71 469 50.1 4.78 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 70.29 1 18 18 242 5.061E9 233.68 70.29 18 121 16027.78 70.29 18 121 350 37.6 4.54 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 68.68 1 15 15 84 9.972E8 95.45 68.68 15 42 5943.67 68.68 15 42 281 30.6 4.59 HVO_0104 DNA repair and recombination protein RadA 68.22 1 17 17 113 1.535E9 108.96 62.97 16 57 8410.48 68.22 17 56 343 37.3 4.64 HVO_2862 serine hydroxymethyltransferase 67.23 1 17 17 208 4.225E9 193.53 67.23 17 106 13763.15 67.23 17 102 415 44.3 4.53 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 66.40 1 17 17 125 3.983E9 97.16 66.40 17 62 7170.30 66.40 17 63 381 41.0 4.23 HVO_1921 serine--tRNA ligase 66.09 1 28 28 142 1.080E9 138.14 66.09 28 70 9053.06 66.09 28 72 460 52.0 4.46 HVO_0329 branched-chain amino acid aminotransferase 65.38 1 17 17 101 1.343E9 94.27 65.38 17 53 6445.55 65.38 17 48 312 35.0 4.58 HVO_0348 DNA-directed RNA polymerase subunit B' 65.35 1 33 33 220 1.595E9 212.80 65.35 33 110 13849.12 65.35 33 110 609 67.7 4.92 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 63.99 1 12 12 51 5.113E8 46.94 63.99 12 25 3145.64 63.99 12 26 286 31.2 4.54 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 63.28 1 17 17 74 1.564E9 58.05 58.03 15 35 4961.59 63.28 17 39 305 33.8 4.74 HVO_0055 CBS domain protein 63.03 1 12 12 65 1.274E9 69.13 63.03 12 33 5413.41 63.03 12 32 284 30.8 4.27 HVO_0581 "cell division protein FtsZ, type II" 63.00 1 17 18 105 1.029E9 102.44 61.50 17 53 7339.10 61.25 16 52 400 42.5 4.75 HVO_0455 thermosome subunit 2 62.66 1 28 29 170 1.809E9 161.15 62.66 29 86 11240.33 62.66 29 84 557 59.3 4.37 HVO_1273 inosine-5'-monophosphate dehydrogenase 61.85 1 20 20 238 2.028E9 244.52 59.24 19 117 16248.10 61.85 20 121 498 53.3 4.55 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 61.76 1 17 17 70 4.603E8 57.94 61.76 16 35 4196.39 61.76 17 35 340 38.8 4.58 HVO_0778 thermosome subunit 3 61.45 1 25 27 161 1.609E9 165.25 58.40 25 80 11898.85 61.45 27 81 524 55.2 4.59 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 60.90 1 16 16 82 6.926E8 76.57 60.90 16 41 4979.54 60.90 16 41 422 43.6 4.72 HVO_0025 thiosulfate sulfurtransferase 60.84 1 12 12 253 6.610E9 239.06 59.44 11 130 14152.01 60.84 12 123 286 32.1 4.28 HVO_0602 3-dehydroquinate dehydratase 60.32 1 11 11 40 1.861E8 26.75 60.32 11 19 2193.33 60.32 11 21 247 27.3 4.51 HVO_0161 ATP phosphoribosyltransferase 60.14 1 13 13 71 4.953E8 66.39 60.14 13 38 4803.49 60.14 13 33 281 30.4 4.60 HVO_0347 DNA-directed RNA polymerase subunit B'' 60.08 1 29 29 187 1.268E9 145.85 58.35 28 94 11413.55 60.08 28 93 521 58.9 5.00 HVO_2756 50S ribosomal protein L10 60.06 1 14 14 98 1.271E9 72.37 58.33 13 49 6010.27 60.06 14 49 348 36.9 3.99 HVO_2621 phosphoenolpyruvate carboxylase 59.53 1 43 43 307 2.302E9 276.49 56.63 42 154 19202.30 59.53 43 153 897 102.3 4.64 HVO_2413 translation elongation factor aEF-1 alpha subunit 59.52 1 14 18 144 5.748E9 84.80 55.24 17 69 8023.05 59.52 18 75 420 45.6 4.75 HVO_0859 FeS assembly ATPase SufC 59.47 1 17 17 159 2.794E9 124.16 57.48 15 80 9841.06 59.47 17 79 301 33.4 4.35 HVO_2191 formyltetrahydrofolate deformylase 59.33 1 16 16 81 1.010E9 72.82 59.33 16 40 5337.58 59.33 16 41 327 36.2 4.63 HVO_0861 SufB domain protein 59.20 1 16 16 126 2.355E9 129.22 55.72 15 65 9069.45 52.99 15 61 402 44.7 4.23 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 58.92 1 13 13 74 1.246E9 54.02 54.21 12 36 4001.57 58.92 13 38 297 31.3 4.36 HVO_0239 glutamine synthetase 58.77 1 20 22 147 3.515E9 146.07 58.77 21 72 9830.06 57.46 20 75 456 50.5 4.56 HVO_0850 proteasome-activating nucleotidase 58.52 1 16 17 106 7.961E8 136.20 51.60 15 53 7644.18 58.52 17 53 405 45.6 4.60 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 58.33 1 11 11 173 3.551E9 169.59 58.33 11 87 11520.59 58.33 11 86 312 34.5 4.98 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 58.31 1 13 13 44 5.662E8 34.50 58.31 13 22 2610.39 58.31 13 22 355 38.2 4.68 HVO_0677 aspartate--tRNA ligase 58.29 1 18 18 234 4.033E9 258.86 53.00 17 117 16388.50 58.29 17 117 434 48.7 4.50 HVO_2968 phosphoglycerate dehydrogenase 58.29 1 20 20 178 2.831E9 206.93 56.57 19 87 13969.33 58.29 20 91 525 55.3 4.36 HVO_1541 glycerol kinase 58.04 1 22 22 151 3.110E9 112.61 54.71 21 75 9534.02 50.20 20 76 510 56.7 4.50 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 57.74 1 18 18 67 4.135E8 57.69 57.74 18 33 4207.27 57.74 18 34 336 38.0 4.61 HVO_0869 glutamate synthase large subunit 57.64 1 71 72 449 2.106E9 439.19 56.59 70 227 29598.62 57.58 69 222 1511 163.8 4.70 HVO_2544 30S ribosomal protein S5 57.48 1 10 10 67 3.211E9 49.31 54.67 9 32 3706.39 57.48 10 35 214 23.3 9.29 HVO_0870 proline--tRNA ligase 57.17 1 19 19 100 1.084E9 79.46 50.61 17 48 5977.58 57.17 19 52 488 54.9 4.44 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 57.14 1 14 14 78 5.960E8 89.06 57.14 14 40 6116.05 57.14 14 38 343 38.4 4.94 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 57.14 1 6 6 28 1.882E8 19.80 50.26 5 14 1298.30 57.14 6 14 189 21.7 4.46 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 56.51 1 15 15 138 2.816E9 162.02 56.51 15 68 11192.50 56.51 15 70 384 41.4 4.41 HVO_2889 RecJ domain protein 56.38 1 31 31 212 2.800E9 216.80 56.38 31 107 14738.70 55.69 30 105 729 79.1 4.37 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 56.12 1 21 21 99 5.543E8 105.20 54.01 18 49 6815.93 56.12 21 50 474 53.4 4.59 HVO_2724 beta-lactamase domain protein 56.00 1 21 21 208 2.406E9 179.06 53.33 19 103 12382.15 56.00 21 105 450 50.1 5.40 HVO_0860 SufB domain protein 55.88 1 21 21 187 2.302E9 184.11 47.48 19 88 13141.84 55.88 21 99 476 53.2 4.69 HVO_2588 isocitrate dehydrogenase (NADP) 55.85 1 20 20 203 4.771E9 189.65 52.74 19 100 14195.00 55.85 20 103 419 45.8 4.59 HVO_1133 conserved hypothetical protein 55.45 1 4 4 18 9.269E7 15.37 55.45 4 9 1308.08 55.45 4 9 101 11.7 4.58 HVO_1338 replication protein A 55.04 1 17 18 65 3.752E8 52.20 55.04 18 33 3545.12 53.86 17 32 427 46.0 4.36 HVO_2384 CBS domain protein 54.47 1 17 18 118 1.447E9 92.42 53.16 17 59 7009.15 54.47 18 59 380 42.5 5.01 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 54.42 1 13 13 44 5.170E8 43.41 51.38 12 22 2798.43 50.83 11 22 362 39.6 4.82 HVO_1284 GTP cyclohydrolase III 54.41 1 9 9 30 3.575E8 24.59 38.31 7 14 1658.67 54.41 9 16 261 28.9 4.70 HVO_2336 pyridoxal biosynthesis lyase PdxS 54.30 1 12 12 53 3.380E8 49.60 41.72 9 24 3489.92 54.30 12 29 302 32.5 4.81 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 54.05 1 14 14 69 6.438E8 73.39 54.05 14 34 4759.22 54.05 14 35 457 48.4 4.35 HVO_2969 threonine synthase 53.94 1 17 17 85 1.649E9 93.37 48.21 16 42 6551.75 53.94 17 43 419 44.4 4.49 HVO_0317 A-type ATP synthase subunit B 53.85 1 15 17 134 3.210E9 156.68 53.85 17 68 10016.07 53.85 17 66 468 51.9 4.25 HVO_1684 threonine--tRNA ligase 53.65 1 30 30 156 1.379E9 146.35 53.65 30 78 10222.03 53.65 30 78 643 73.4 4.45 HVO_2059 NAD-dependent epimerase/dehydratase 53.55 1 11 11 46 5.959E8 33.52 53.55 11 23 2861.61 53.55 11 23 310 34.1 4.40 HVO_2700 AAA-type ATPase (CDC48 subfamily) 53.45 1 36 37 130 3.274E8 103.34 51.99 35 65 6661.03 52.52 36 65 754 82.8 4.75 HVO_2519 conserved hypothetical protein 53.40 1 13 13 72 6.504E8 90.65 48.69 12 33 6359.47 53.40 13 39 382 40.7 4.35 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 53.38 1 22 22 155 1.850E9 133.89 53.38 22 78 9525.61 53.38 22 77 592 66.6 4.61 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 53.33 1 13 13 66 6.700E8 46.81 51.39 12 32 4133.56 53.33 13 34 360 39.6 4.39 HVO_2013 "FtsZ family protein, type III" 53.30 1 11 11 46 4.792E8 53.52 53.30 11 23 3654.95 47.46 10 23 394 41.5 4.61 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 52.82 1 25 25 117 8.352E8 91.97 51.21 24 58 6611.17 50.20 24 59 496 55.0 4.53 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 52.81 1 8 9 25 2.211E8 13.70 52.81 9 12 996.65 52.81 9 13 267 29.1 4.63 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 52.76 1 8 8 36 5.185E8 34.37 44.49 7 17 2519.36 52.76 8 19 254 26.9 4.42 HVO_1332 conserved hypothetical protein 52.71 1 6 6 16 2.608E8 8.33 27.91 4 7 1056.29 47.29 5 9 129 14.9 4.16 HVO_0393 UvrABC system protein A 52.70 1 39 39 155 2.854E8 167.56 51.27 37 77 9781.41 52.70 39 78 983 108.6 4.82 HVO_0240 Lrp/AsnC family transcription regulator 52.63 1 6 7 32 5.009E8 17.34 47.37 6 15 1672.90 52.63 7 17 152 16.9 4.39 HVO_1132 adenylosuccinate synthase 52.37 1 23 23 168 3.145E9 140.06 49.21 22 83 10355.55 52.37 23 85 443 48.2 4.56 HVO_1306 chorismate synthase 52.21 1 13 13 75 2.883E8 77.86 52.21 13 37 4450.05 52.21 13 38 385 41.9 4.83 HVO_1502 3-isopropylmalate dehydrogenase 51.85 1 13 13 82 1.651E9 71.53 42.59 11 39 5852.70 51.85 13 43 324 33.7 4.23 HVO_0292 replication protein A 51.77 1 12 12 49 2.931E8 48.94 51.77 12 24 3383.84 51.77 12 25 311 34.6 4.31 HVO_1189 aldehyde dehydrogenase 51.77 1 20 20 108 1.501E9 98.48 43.31 18 51 6821.70 51.77 20 57 508 56.1 4.59 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 51.60 1 23 23 110 6.310E8 108.02 51.44 22 54 7016.35 51.60 23 56 626 67.6 4.65 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 51.57 1 13 13 95 2.231E9 84.48 51.57 13 47 5932.52 51.57 13 48 413 45.8 4.45 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 51.56 1 21 21 100 1.021E9 90.29 51.56 20 49 6861.41 47.46 20 51 512 53.8 4.78 HVO_A0406 conserved hypothetical protein 51.36 1 3 13 54 5.134E8 44.93 51.36 13 28 3338.52 48.89 12 26 405 44.4 5.30 HVO_1084 adenylosuccinate lyase 51.19 1 20 20 84 6.226E8 64.56 43.63 18 41 5201.62 46.65 18 43 463 50.8 4.70 HVO_1123 thioredoxin-disulfide reductase 51.00 1 12 12 51 6.612E8 43.11 47.85 11 23 2794.81 51.00 12 28 349 37.3 4.32 HVO_1973 conserved hypothetical protein 50.90 1 5 5 31 2.771E8 31.45 41.92 4 15 2607.95 50.90 5 16 167 18.1 4.36 HVO_1506 ketol-acid reductoisomerase 50.86 1 9 9 62 1.283E9 69.82 50.86 9 33 4088.56 40.52 8 29 348 37.9 4.34 HVO_2624 CTP synthase 50.64 1 20 20 112 8.952E8 87.60 46.81 17 52 7002.14 50.64 20 60 549 60.8 4.70 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 50.64 1 22 22 115 8.262E8 101.37 46.47 21 59 7151.58 45.51 20 56 624 67.6 4.27 HVO_0133 thermosome subunit 1 50.54 1 19 21 163 2.094E9 180.49 43.57 18 82 11858.96 49.29 20 81 560 58.9 4.25 HVO_0046 putative glutamate--argW ligase 50.52 1 11 11 79 8.782E8 78.32 50.52 11 39 5562.52 50.52 11 40 291 31.9 4.87 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 23 2.904E8 10.03 37.91 4 11 878.95 50.33 5 12 153 16.9 4.21 HVO_2783 30S ribosomal protein S4 50.29 1 11 11 58 1.415E9 48.67 50.29 11 29 3587.49 50.29 11 29 175 20.1 5.24 HVO_1370 gamma-glutamyl phosphate reductase 50.00 1 17 17 78 6.333E8 68.14 50.00 17 39 4470.04 50.00 17 39 444 48.1 4.34 HVO_0480 phosphoglycerate kinase 49.88 1 18 18 108 1.312E9 102.95 48.13 17 53 8047.85 49.88 18 55 401 43.6 4.37 HVO_2774 enolase 49.87 1 12 12 61 1.349E9 58.80 49.87 12 31 3949.29 43.61 11 30 399 42.0 4.37 HVO_0467 PhoU/TrkA-C domain protein 49.75 1 18 18 61 1.600E8 43.86 47.76 17 31 3250.04 49.75 18 30 402 43.3 4.49 HVO_1145 30S ribosomal protein S1e 49.55 1 11 11 61 1.287E9 67.57 49.55 11 30 4614.30 49.55 11 31 220 24.8 4.86 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 49.44 1 14 14 66 4.511E8 74.63 49.44 14 33 4118.36 49.44 14 33 445 47.8 4.86 HVO_0729 inorganic pyrophosphatase 49.15 1 8 8 51 1.229E9 55.82 49.15 7 25 3452.30 49.15 8 26 177 20.4 4.16 HVO_1545 dihydroxyacetone kinase subunit DhaL 49.14 1 10 10 47 7.047E8 38.95 46.12 9 22 2915.37 49.14 10 25 232 24.8 4.48 HVO_0206 alanine--tRNA ligase 49.02 1 33 33 192 6.000E8 194.50 48.16 32 94 12595.87 49.02 33 98 922 102.4 4.54 HVO_1080 conserved hypothetical protein 48.94 1 9 9 26 4.081E8 21.07 44.68 7 13 1514.01 48.40 8 13 188 21.1 4.31 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 48.79 1 9 9 92 1.719E9 85.94 39.10 7 43 6977.41 48.79 9 49 289 29.8 4.27 HVO_0789 tryptophan synthase alpha subunit 48.74 1 8 8 39 4.594E8 39.34 48.74 8 21 2759.47 48.74 8 18 277 29.6 4.21 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 48.50 1 10 11 58 2.052E9 70.74 44.74 10 29 4613.88 45.86 10 29 266 27.8 4.84 HVO_1504 3-isopropylmalate dehydratase large subunit 48.41 1 19 20 164 3.320E9 161.65 48.41 20 84 11490.03 48.41 20 80 473 51.6 4.55 HVO_2548 50S ribosomal protein L6 48.31 1 6 6 20 1.428E8 25.82 48.31 6 10 1594.21 48.31 6 10 178 19.6 4.68 HVO_2015 conserved hypothetical protein 48.12 1 11 11 162 7.179E9 170.01 48.12 11 79 11072.89 48.12 11 83 345 37.7 4.25 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 48.08 1 10 10 104 1.382E9 107.19 46.34 9 53 7185.63 48.08 10 51 287 31.0 4.73 HVO_A0207 CRISPR-associated protein Cas7 47.94 1 10 10 55 9.003E8 57.67 47.94 10 28 3782.97 47.94 10 27 340 38.2 4.54 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 47.89 1 6 6 43 9.413E8 35.59 47.89 6 22 3253.91 47.89 6 21 190 20.6 4.30 HVO_0353 30S ribosomal protein S12 47.89 1 9 10 47 8.922E8 52.23 43.66 9 23 3010.89 44.37 9 24 142 15.5 9.91 HVO_2204 "FtsZ family protein, type III" 47.85 1 13 16 87 1.355E9 95.57 47.85 16 44 6587.62 47.85 16 43 395 42.0 4.68 HVO_3007 malate dehydrogenase 47.70 1 13 13 147 4.113E9 135.92 47.70 13 73 8193.16 47.70 13 74 304 32.6 4.40 HVO_0024 thiosulfate sulfurtransferase 47.67 1 10 10 47 5.876E8 49.11 43.02 9 22 3186.22 42.64 9 25 258 28.4 4.30 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 47.52 1 8 8 38 1.564E8 32.78 47.52 8 19 2121.15 47.52 8 19 202 22.2 5.11 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 47.39 1 22 22 302 6.290E9 298.23 42.16 20 150 20520.54 46.59 21 152 631 68.4 4.49 HVO_2487 aspartate-semialdehyde dehydrogenase 47.38 1 10 10 59 1.464E9 47.13 47.38 10 29 3447.79 47.38 10 30 344 36.6 4.41 HVO_0433 F420H2:NADP oxidoreductase 47.30 1 7 7 34 4.995E8 33.99 47.30 7 16 2491.27 47.30 7 18 222 23.3 4.72 HVO_2435 peptidase M24 family protein 47.28 1 11 11 46 2.987E8 49.74 47.28 11 23 3225.50 47.28 11 23 368 40.0 4.53 HVO_1082 homolog to orotate phosphoribosyltransferase 47.14 1 9 9 35 5.398E8 27.99 47.14 9 19 1904.60 40.00 7 16 210 22.3 4.42 HVO_A0205 CRISPR-associated endoribonuclease Cas6 47.06 1 12 12 57 3.820E8 58.59 43.75 11 28 3951.14 47.06 12 29 272 31.0 5.44 HVO_2558 30S ribosomal protein S3 47.04 1 13 13 124 3.799E9 121.40 42.76 11 58 9835.49 47.04 13 66 304 33.4 4.06 HVO_2552 30S ribosomal protein S4e 46.96 1 7 7 129 7.330E9 117.31 46.96 7 67 7016.44 46.96 7 62 247 26.6 4.58 HVO_2549 30S ribosomal protein S8 46.92 1 6 6 20 6.177E8 18.82 46.92 6 10 1238.68 46.92 6 10 130 14.1 4.79 HVO_2782 30S ribosomal protein S11 46.92 1 5 5 20 2.560E8 19.83 46.92 5 10 1277.36 46.92 5 10 130 13.4 8.56 HVO_0694 probable phosphoribosyltransferase 46.84 1 11 11 39 1.359E8 34.91 43.46 10 19 2338.78 46.84 11 20 237 27.0 4.32 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 46.79 1 11 11 61 1.562E9 79.16 46.79 11 29 4748.63 46.79 10 32 280 30.1 4.44 HVO_2779 50S ribosomal protein L18e 46.55 1 6 6 18 6.427E7 13.41 46.55 6 9 1002.50 46.55 6 9 116 12.7 8.50 HVO_1955 aconitate hydratase 46.48 1 25 25 226 4.793E9 231.06 45.41 24 111 15908.00 46.48 25 115 654 70.4 4.45 HVO_0717 "cell division protein FtsZ, type I" 46.44 1 15 15 84 1.343E9 74.31 46.44 15 43 5688.90 46.44 15 41 379 39.8 4.40 HVO_0999 DRTGG domain protein 46.30 1 12 12 71 4.925E8 83.30 46.30 12 35 5531.02 46.30 12 36 378 39.8 4.44 HVO_1690 DHH family phosphoesterase 46.19 1 12 12 54 1.921E8 58.75 46.19 12 27 3617.12 46.19 12 27 485 52.1 4.48 HVO_2188 phosphoribosylformylglycinamidine synthase 1 45.54 1 8 8 34 6.684E8 34.73 45.54 8 17 2476.03 45.54 8 17 224 23.9 4.36 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 45.54 1 9 9 50 5.501E8 61.75 40.18 8 24 4376.47 45.54 9 26 336 36.8 4.12 HVO_A0206 CRISPR-associated protein Cas8b 45.47 1 24 24 87 4.695E8 84.09 42.12 22 43 5494.40 45.47 24 44 717 79.3 4.60 HVO_0167 adenosylhomocysteinase 45.33 1 13 13 70 5.383E8 67.78 41.12 12 34 4627.80 45.33 13 36 428 46.6 4.39 HVO_1300 triosephosphate isomerase 45.33 1 6 6 52 1.549E9 53.99 45.33 6 25 3193.74 45.33 6 27 214 21.3 4.26 HVO_0316 A-type ATP synthase subunit A 45.22 1 21 21 172 2.774E9 211.07 45.22 21 86 13717.44 45.22 21 86 586 64.5 4.25 HVO_0874 beta-lactamase domain protein 45.16 1 25 25 121 1.240E9 119.01 44.22 24 60 8603.52 45.16 25 61 640 71.9 5.14 HVO_0809 methionine--tRNA ligase 45.14 1 23 23 124 7.643E8 134.06 45.14 23 63 9362.59 43.65 22 61 740 81.9 4.37 HVO_2981 uracil phosphoribosyltransferase 45.13 1 10 10 46 8.724E8 51.66 42.92 9 21 4076.89 45.13 10 25 226 24.5 4.49 HVO_0388 homolog to ribonuclease R 45.10 1 18 18 88 5.349E8 80.88 45.10 18 43 6068.31 45.10 18 45 439 50.3 4.73 HVO_1637 FKBP-type peptidylprolyl isomerase 44.77 1 10 11 90 3.853E9 99.36 36.27 10 43 6974.55 44.77 11 47 306 33.8 3.76 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 44.76 1 17 17 116 1.759E9 116.22 42.86 16 57 8532.75 44.76 17 59 525 56.4 4.40 HVO_2419 hydroxymethylglutaryl-CoA synthase 44.72 1 16 16 84 8.764E8 63.03 44.72 16 41 5014.86 44.72 16 43 445 50.1 4.64 HVO_0175 DNA polymerase sliding clamp 44.53 1 7 7 89 3.056E9 63.80 44.53 7 45 5044.02 35.22 6 44 247 26.7 4.39 HVO_1824 conserved hypothetical protein 44.52 1 13 13 50 2.625E8 62.90 44.52 13 25 3925.55 44.52 13 25 429 47.4 4.20 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 44.47 1 16 16 62 4.900E8 34.32 44.47 16 32 3118.48 39.26 14 30 461 50.7 4.73 HVO_0449 prephenate dehydratase 44.40 1 9 9 37 5.914E8 41.47 44.40 9 19 2528.05 44.40 9 18 268 28.7 4.64 HVO_1867 lysine--tRNA ligase 44.32 1 17 17 62 1.671E8 45.95 44.32 17 31 3305.27 38.56 16 31 555 62.1 4.46 HVO_A0636 YbaK domain protein 44.30 1 4 4 16 1.192E8 24.35 44.30 4 8 1438.39 44.30 4 8 158 16.7 4.54 HVO_0511 NAD-dependent epimerase/dehydratase 44.27 1 8 8 35 1.660E8 26.58 35.11 7 16 1938.72 39.69 7 19 262 29.3 4.78 HVO_0314 A-type ATP synthase subunit C 44.25 1 15 15 63 9.062E8 52.02 40.23 14 30 4290.12 44.25 15 33 348 38.7 4.50 HVO_2130 IclR family transcription regulator 44.12 1 12 12 35 2.027E8 31.03 44.12 11 17 2115.44 43.75 11 18 272 30.1 5.55 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 44.11 1 14 14 59 6.441E8 41.69 42.97 13 29 3439.16 44.11 14 30 526 57.2 4.31 HVO_0349 DNA-directed RNA polymerase subunit A' 44.06 1 36 36 208 1.155E9 200.50 42.62 35 105 14252.32 43.55 35 103 976 108.8 4.81 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 44.03 1 20 20 171 2.109E9 158.68 44.03 20 88 11276.46 43.00 19 83 586 64.0 4.49 HVO_0980 NADH dehydrogenase-like complex subunit CD 43.99 1 16 21 106 8.583E8 90.35 43.99 21 53 6726.18 43.99 21 53 557 63.4 4.53 HVO_A0458 ParA domain protein 43.99 1 8 8 23 1.107E8 20.27 43.99 8 12 1116.87 38.83 7 11 291 32.2 4.79 HVO_0806 pyruvate kinase 43.93 1 17 17 118 1.191E9 117.65 43.93 17 59 8088.07 43.93 17 59 585 62.0 4.54 HVO_2646 dihydroxy-acid dehydratase 43.84 1 18 18 124 1.165E9 127.99 43.84 18 62 8887.98 43.84 18 62 584 61.8 4.42 HVO_0313 A-type ATP synthase subunit E 43.81 1 6 7 32 3.483E8 27.89 34.02 5 14 2217.82 43.81 7 18 194 22.0 4.31 HVO_2454 anthranilate synthase component I 43.70 1 19 19 87 4.817E8 90.40 43.70 19 44 5920.32 43.70 19 43 524 55.9 4.56 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 43.63 1 9 9 44 8.020E8 52.11 43.63 9 21 3381.90 43.63 9 23 259 28.0 4.50 HVO_0792 3-dehydroquinate synthase type II 43.37 1 12 13 83 8.070E8 92.92 43.37 13 42 6146.05 42.09 12 41 392 43.1 4.44 HVO_1091 proteasome alpha subunit 43.25 1 10 11 51 1.241E9 56.67 43.25 11 26 3492.81 43.25 11 25 252 27.6 4.56 HVO_1590 DnaK-type molecular chaperone Hsp70 43.20 1 25 25 224 2.570E9 168.65 43.20 25 110 12521.90 43.20 25 114 625 67.2 4.18 HVO_B0118 SMC-like protein Sph2 43.17 1 27 28 122 1.059E9 114.86 43.17 27 60 7351.31 42.39 27 62 644 73.8 4.41 HVO_0415 repair helicase 42.86 1 20 20 94 7.141E8 90.25 42.86 20 45 6571.54 42.86 20 49 616 69.6 4.70 HVO_0203 replication factor C small subunit 42.51 1 12 12 57 4.232E8 66.19 42.51 12 28 4453.35 42.51 12 29 327 36.2 4.51 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 42.38 1 13 13 69 5.214E8 62.50 42.38 13 34 3877.24 42.38 13 35 453 47.5 4.63 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 42.15 1 10 11 55 2.276E8 40.98 42.15 11 27 2939.78 42.15 11 28 363 39.3 4.97 HVO_2425 GNAT family acetyltransferase 42.13 1 7 7 33 3.137E8 24.74 42.13 7 16 1868.53 42.13 7 17 216 24.4 4.54 HVO_0138 tyrosine--tRNA ligase 42.07 1 10 10 44 4.518E8 30.56 42.07 10 22 2430.83 42.07 10 22 328 36.1 4.34 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 41.99 1 7 7 31 2.477E8 25.08 41.99 7 15 1973.09 41.99 7 16 231 25.0 4.25 HVO_0212 homolog to lactoylglutathione lyase 41.94 1 3 3 10 2.110E8 11.93 41.94 3 5 679.22 41.94 3 5 124 13.5 4.13 HVO_2773 30S ribosomal protein S2 41.92 1 7 7 58 3.299E9 53.62 41.92 7 27 4000.07 41.92 7 31 260 28.3 4.16 HVO_0196 conserved hypothetical protein 41.82 1 2 2 3 2.211E8 5.68 41.82 2 3 55 6.2 4.81 HVO_2057 sugar nucleotidyltransferase 41.74 1 12 12 63 9.079E8 65.26 41.74 12 31 4398.28 41.74 12 32 357 37.8 4.44 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 41.72 1 38 38 220 1.198E9 210.40 40.27 36 111 14351.37 41.72 38 109 1033 114.3 4.45 HVO_2813 RimK family protein 41.72 1 14 14 98 9.241E8 93.58 41.72 14 49 6770.64 41.72 14 49 453 49.0 4.73 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 41.63 1 13 13 50 2.625E8 47.18 41.63 13 25 3240.46 41.63 13 25 454 48.5 4.46 HVO_1031 thioredoxin-disulfide reductase 41.52 1 10 10 50 4.466E8 47.43 39.77 9 24 3079.78 41.52 10 26 342 37.4 4.46 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 41.50 1 20 20 90 3.586E8 86.51 35.50 18 44 6266.57 41.50 20 46 600 65.3 4.68 HVO_0484 50S ribosomal protein L10e 41.48 1 7 7 23 2.133E8 23.42 41.48 7 12 1581.47 36.36 6 11 176 19.8 8.72 HVO_0536 ferritin 41.48 1 4 4 18 1.833E8 28.07 41.48 4 10 1109.04 31.25 3 8 176 19.9 4.50 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 41.40 1 16 16 80 5.824E8 72.27 36.94 14 38 5160.11 41.40 16 42 471 51.0 4.48 HVO_2726 glutamate--tRNA ligase 41.37 1 20 20 103 5.778E8 69.35 41.37 20 51 5335.55 41.37 20 52 585 65.2 4.58 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 41.31 1 12 12 77 1.209E9 50.18 37.45 11 37 4585.94 41.31 12 40 259 29.9 4.36 HVO_1572 DNA gyrase subunit B 41.31 1 23 23 114 6.514E8 84.95 41.31 23 58 6476.51 41.31 23 56 639 71.2 4.83 HVO_2883 conserved hypothetical protein 41.17 1 20 20 78 1.660E8 80.75 41.17 20 40 5366.71 38.46 19 38 702 78.9 4.48 HVO_0829 peptidase S9 family protein 41.12 1 13 13 40 2.355E8 31.17 41.12 13 20 2051.85 41.12 13 20 608 67.4 4.54 HVO_1164 HD family hydrolase 41.11 1 10 10 34 3.062E8 17.78 37.04 9 16 2215.98 41.11 10 18 270 29.8 4.87 HVO_1783 conserved hypothetical protein 41.07 1 6 6 19 7.054E7 10.52 41.07 6 9 910.39 41.07 6 10 224 24.1 5.90 HVO_0350 DNA-directed RNA polymerase subunit A'' 41.05 1 17 17 74 1.372E9 71.86 35.56 16 39 4564.90 39.86 16 35 419 46.1 4.35 HVO_0417 metal-dependent carboxypeptidase 41.04 1 15 15 53 3.417E8 48.56 36.06 13 25 3770.51 41.04 15 28 502 57.3 4.42 HVO_2436 malic enzyme (NADP) 41.01 1 21 25 116 3.552E8 99.91 36.88 24 56 7590.35 38.08 24 60 751 81.4 4.55 HVO_2040 NAD-dependent epimerase/dehydratase 40.85 1 5 11 57 9.130E8 52.21 40.85 11 28 3756.25 40.85 11 29 306 33.8 4.51 HVO_0406 RNA-binding protein AU-1 40.81 1 14 14 51 1.967E8 42.88 40.81 14 26 3034.46 38.89 13 25 468 49.9 4.53 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 40.61 1 9 9 39 2.243E8 40.54 40.61 8 19 2274.26 40.61 9 20 330 36.3 4.35 HVO_0321 peptide chain release factor aRF-1 40.58 1 15 15 51 3.724E8 24.13 38.41 14 25 2634.79 38.65 14 26 414 46.6 4.83 HVO_0519 replication protein A 40.58 1 16 17 73 4.685E8 70.51 40.58 17 36 5137.58 38.30 16 37 483 51.0 4.13 HVO_0661 dCTP deaminase (dUMP-forming) 40.51 1 5 5 25 1.072E8 15.26 40.51 5 12 1132.14 40.51 5 13 195 21.2 4.59 HVO_0109 cysteine desulfurase 40.38 1 13 13 63 4.094E8 64.83 40.38 13 31 4400.63 39.20 12 32 426 46.8 4.56 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 38 2.490E8 38.54 32.47 4 20 2946.98 40.26 5 18 154 17.5 4.50 HVO_0243 threonine aldolase 40.18 1 9 9 43 1.479E8 50.12 40.18 9 22 3259.32 40.18 9 21 341 35.6 4.55 HVO_A0432 conserved hypothetical protein 40.00 1 1 11 41 3.856E8 36.33 40.00 11 22 2610.44 37.53 10 19 405 44.5 5.24 HVO_1932 2-D-hydroxyacid dehydrogenase 39.94 1 9 9 24 1.324E8 17.09 28.90 7 11 1117.84 39.94 9 13 308 33.0 4.60 HVO_2333 conserved hypothetical protein 39.94 1 9 9 24 9.001E7 12.89 39.94 9 12 836.40 39.94 9 12 308 34.9 4.54 HVO_1854 histidine--tRNA ligase 39.91 1 14 14 66 5.727E8 75.61 38.05 13 32 4640.02 39.91 14 34 431 47.1 4.37 HVO_1212 KaiC-type circadian regulator CirA 39.84 1 9 9 48 1.117E9 59.05 39.84 9 24 3977.29 39.84 9 24 246 27.5 4.45 HVO_0008 aspartate kinase 39.54 1 11 11 53 1.666E9 49.34 39.54 11 27 3381.56 38.01 10 26 392 41.7 4.46 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 39.53 1 13 13 45 2.526E8 33.25 39.53 13 22 2396.11 39.53 13 23 473 50.8 4.58 HVO_0324 arginine--tRNA ligase 39.52 1 19 19 92 1.010E9 102.20 39.52 19 46 6603.08 39.52 19 46 587 65.0 4.35 HVO_A0496 UspA domain protein 39.31 1 10 10 57 4.305E8 54.20 39.31 10 28 3596.93 39.31 10 29 290 31.4 4.60 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 39.20 1 10 10 42 8.288E7 33.57 32.72 9 19 2470.04 39.20 10 23 324 36.6 4.68 HVO_1901 translation initiation factor aIF-2 gamma subunit 39.17 1 13 13 91 1.394E9 55.44 39.17 13 46 4578.91 39.17 13 45 411 43.9 4.36 HVO_1018 RecJ domain protein 39.02 1 25 25 138 1.099E9 112.79 39.02 25 69 8888.23 36.02 24 69 633 69.8 4.58 HVO_0743 probable phosphodiesterase 38.98 1 22 22 110 9.752E8 95.44 38.98 22 55 6953.17 37.64 21 55 449 50.5 4.56 HVO_1577 conserved hypothetical protein 38.98 1 7 7 24 3.425E8 25.28 27.68 5 11 1612.61 38.98 7 13 177 19.4 4.74 HVO_0400 conserved hypothetical protein 38.89 1 3 3 10 9.888E7 11.06 38.89 3 5 753.72 38.89 3 5 126 13.9 4.68 HVO_1778 catalase-peroxidase 38.72 1 20 20 98 1.420E9 93.99 38.02 19 49 6503.70 38.02 19 49 718 80.0 4.31 HVO_1465 naphthoate synthase 38.69 1 7 7 31 2.425E8 35.37 30.16 6 15 2327.48 38.69 7 16 305 33.9 4.83 HVO_1125 cysteine--tRNA ligase 38.66 1 14 14 55 4.199E8 64.71 38.66 14 27 3773.31 38.66 14 28 494 55.2 4.56 HVO_B0059 cobalt-precorrin 5A hydrolase 38.65 1 9 9 34 1.483E8 28.43 27.30 7 16 2210.21 38.65 9 18 326 34.5 4.51 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 38.62 1 11 11 60 9.879E8 63.94 30.80 10 30 4022.71 38.62 11 30 435 46.9 4.63 HVO_0017 conserved hypothetical protein 38.54 1 4 5 20 1.574E8 9.57 38.54 5 10 1112.61 38.54 5 10 192 21.9 4.50 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 38.50 1 9 9 51 6.004E8 45.69 38.50 9 24 3406.64 38.50 9 27 226 25.5 4.25 HVO_0911 GTP-binding protein Drg 38.48 1 12 12 37 8.945E7 22.27 35.50 11 19 2239.46 38.48 12 18 369 40.5 4.81 HVO_2348 GTP cyclohydrolase MptA 38.31 1 7 7 45 3.301E8 24.21 29.22 6 23 2005.16 38.31 7 22 308 33.5 4.68 HVO_2547 50S ribosomal protein L32e 38.30 1 8 8 32 3.594E8 28.39 31.06 7 16 2196.00 35.74 7 16 235 25.8 4.75 HVO_0424 ABC-type transport system ATP-binding protein 38.25 1 18 18 93 4.018E8 93.51 36.26 17 45 5176.14 38.25 18 48 604 67.2 4.49 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 38.22 1 12 12 74 6.152E8 76.61 38.22 12 37 4897.52 38.22 12 37 348 38.2 4.32 HVO_2723 RNA-binding protein Lsm 38.16 1 2 2 2 1.963E7 203.50 38.16 2 2 76 8.3 4.09 HVO_0788 tryptophan synthase beta subunit 38.15 1 13 13 54 4.331E8 49.97 38.15 13 27 3389.31 38.15 13 27 422 45.7 4.65 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 76 6.701E8 80.38 35.50 8 37 5469.75 38.05 9 39 431 46.1 4.48 HVO_0049 argininosuccinate synthase 37.28 1 14 14 75 1.671E9 61.00 37.28 14 38 4559.00 37.28 14 37 405 44.5 4.34 HVO_2643 NADPH:quinone reductase 37.28 1 9 9 51 1.733E8 32.67 37.28 9 26 2561.14 35.55 8 25 346 37.2 4.55 HVO_0354 30S ribosomal protein S7 37.25 1 7 7 27 4.938E8 20.75 28.43 6 13 1736.93 37.25 7 14 204 22.6 5.14 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.05 1 11 11 80 1.090E9 54.86 37.05 11 40 3984.01 37.05 11 40 332 34.8 4.22 HVO_2918 thymidylate synthase 37.05 1 7 7 20 1.143E8 16.11 37.05 7 10 1320.00 37.05 7 10 332 37.5 4.61 HVO_1654 cysteine synthase 36.93 1 8 8 32 3.004E8 34.70 36.93 8 16 2025.39 36.93 8 16 306 32.3 4.32 HVO_B0061 precorrin-2 C20-methyltransferase 36.60 1 7 7 27 1.163E8 23.29 36.60 7 13 1443.38 36.60 7 14 235 25.3 4.63 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 36.56 1 15 15 62 3.742E8 74.83 36.56 15 31 5529.33 36.56 15 31 599 65.3 4.51 HVO_0041 ornithine carbamoyltransferase 36.45 1 7 7 47 4.163E8 48.98 36.45 7 23 2959.18 36.45 7 24 299 32.7 4.37 HVO_1571 DNA topoisomerase VI subunit B 36.34 1 21 21 87 4.354E8 72.00 33.96 20 42 5419.48 36.34 21 45 798 87.4 4.73 17318569 keratin 1 [Homo sapiens] 36.18 1 1 24 110 6.104E8 110.05 36.18 24 54 7981.16 36.18 24 56 644 66.0 8.12 HVO_A0266 IclR family transcription regulator 36.08 1 7 7 28 1.254E8 20.50 36.08 7 14 1617.34 36.08 7 14 255 27.7 6.05 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 36.08 1 4 4 27 9.520E8 31.56 25.26 3 11 2677.28 36.08 4 16 194 20.7 4.12 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 36.01 1 16 16 98 6.138E8 89.02 36.01 16 50 6197.81 36.01 16 48 586 63.4 4.70 HVO_1649 methionine adenosyltransferase 35.82 1 12 12 44 2.443E8 42.89 35.82 12 22 2945.20 35.82 12 22 402 43.5 4.45 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 35.56 1 8 8 43 2.310E8 44.20 35.56 8 22 2686.80 35.56 8 21 270 29.1 4.35 HVO_1097 diaminopimelate epimerase 35.42 1 6 6 17 1.909E8 17.92 31.94 5 8 1161.78 35.42 6 9 288 29.9 4.48 HVO_0549 2-keto-3-deoxygluconate kinase 35.31 1 9 10 38 4.600E8 26.52 31.56 9 18 2641.47 35.31 10 20 320 34.1 4.34 HVO_1574 NUDIX family hydrolase 35.26 1 4 4 8 3.277E7 3.49 32.05 3 4 502.12 25.00 3 4 156 17.6 4.98 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 35.21 1 7 8 26 1.003E8 25.38 35.21 8 13 1482.16 35.21 8 13 267 28.8 4.55 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 35.12 1 12 12 74 4.942E8 62.21 35.12 12 37 4312.00 35.12 12 37 447 48.5 4.56 HVO_1076 sugar nucleotidyltransferase 35.09 1 7 7 44 5.115E8 51.80 35.09 7 22 3344.57 35.09 7 22 322 35.8 4.20 HVO_0452 leucine--tRNA ligase 34.97 1 26 26 103 6.284E8 100.10 33.19 24 52 7604.16 32.15 25 51 958 109.5 4.37 HVO_2481 HD family hydrolase 34.87 1 8 8 16 1.087E8 8.72 28.21 7 8 699.16 32.82 7 8 390 42.7 6.14 HVO_2675 histidinol dehydrogenase 34.81 1 10 10 41 3.865E8 34.68 34.81 10 20 2981.08 34.81 10 21 428 45.4 4.50 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 34.78 1 0 23 106 6.104E8 105.20 34.78 23 52 7681.00 34.78 23 54 644 66.0 8.12 HVO_1576 NAD-dependent epimerase/dehydratase 34.64 1 5 11 48 6.803E8 32.37 33.01 10 23 2918.29 34.64 11 25 306 33.9 4.51 HVO_1295 histidinol-phosphate aminotransferase 34.63 1 9 9 32 1.149E8 27.78 34.63 9 16 1687.63 34.63 9 16 361 39.4 4.51 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 34.59 1 14 14 117 1.248E9 97.74 34.59 14 59 7190.85 34.59 14 58 370 41.9 4.48 HVO_1371 glutamate 5-kinase 34.55 1 7 7 30 5.461E8 36.31 34.55 7 15 2396.95 34.55 7 15 301 32.0 4.25 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 34.52 1 11 11 38 1.413E8 38.85 34.52 11 19 2538.13 34.52 11 19 420 45.0 4.86 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 34.43 1 10 10 35 2.393E8 17.65 34.43 10 18 1793.07 34.43 10 17 427 45.4 4.56 HVO_2417 conserved hypothetical protein 34.36 1 5 5 25 3.904E8 28.28 31.28 4 12 1663.93 34.36 5 13 195 21.6 3.65 HVO_1573 DNA gyrase subunit A 34.22 1 26 26 118 5.857E8 101.14 34.22 26 59 7191.62 33.06 25 59 862 94.8 4.56 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 34.15 1 7 7 30 8.630E7 32.23 34.15 7 15 1715.86 34.15 7 15 287 31.8 4.93 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 34.04 1 5 5 28 3.859E8 10.95 34.04 5 14 1111.40 34.04 5 14 188 20.5 4.60 HVO_0979 NADH dehydrogenase-like complex subunit B 33.91 1 7 7 23 1.810E8 21.44 33.91 7 12 1131.99 31.33 6 11 233 26.1 5.01 HVO_1025 acetyl-CoA C-acyltransferase 33.68 1 10 10 34 4.065E8 26.68 33.68 10 17 1907.60 33.68 10 17 383 40.7 4.56 HVO_2961 dihydrolipoyl dehydrogenase 33.68 1 12 12 54 3.620E8 53.96 28.21 11 26 3885.33 33.68 12 28 475 49.9 4.41 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 33.52 1 10 10 53 2.782E8 51.05 33.52 10 26 3975.70 33.52 10 27 364 39.3 4.35 HVO_0541 aconitate hydratase 33.48 1 22 22 63 3.141E8 23.66 29.21 19 29 3090.45 32.52 21 34 938 102.1 4.40 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 33.33 1 9 9 36 1.652E8 34.64 33.33 9 18 2383.06 33.33 9 18 333 36.7 4.56 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 33.33 1 6 7 23 5.921E8 24.53 26.59 6 12 1863.36 33.33 7 11 252 26.0 4.39 HVO_B0371 aldehyde dehydrogenase 33.27 1 9 9 33 1.307E8 41.08 33.27 9 17 2403.41 33.27 9 16 496 52.5 4.39 HVO_1459 ThuA family protein 33.19 1 4 4 19 5.340E8 33.98 33.19 4 10 1677.63 22.69 3 9 238 26.8 4.67 HVO_1250 redoxin domain protein 33.16 1 3 3 7 3.798E7 2.22 27.27 2 2 451.04 33.16 3 5 187 20.5 4.03 HVO_1481 UspA domain protein 33.13 1 4 4 28 5.587E8 24.17 33.13 4 14 1612.34 33.13 4 14 163 17.7 4.40 HVO_0601 homoserine dehydrogenase 32.91 1 5 6 27 4.199E8 35.76 32.91 6 14 2424.15 32.91 6 13 316 32.2 4.25 HVO_0401 UspA domain protein 32.89 1 4 4 14 4.069E8 12.32 32.89 4 7 923.44 32.89 4 7 152 16.4 4.79 HVO_1880 conserved hypothetical protein 32.89 1 6 7 26 9.211E7 19.06 30.22 6 12 1705.68 32.89 7 14 225 23.8 4.59 HVO_1491 HAD superfamily hydrolase 32.84 1 11 11 37 1.128E8 23.07 31.13 10 18 1865.78 27.94 10 19 408 44.4 4.60 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 32.83 1 7 7 27 9.085E7 35.32 32.83 7 14 2318.06 32.83 7 13 265 29.3 4.92 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 32.77 1 9 9 50 7.166E8 46.09 32.77 9 25 2807.95 32.77 9 25 415 44.4 4.41 HVO_2256 DUF262 family protein 32.68 1 14 14 49 2.570E8 32.73 27.71 12 23 3161.81 30.95 13 26 462 54.9 4.89 HVO_2913 superoxide dismutase (Mn) 32.66 1 0 4 22 1.956E9 24.65 32.66 4 11 1760.12 32.66 4 11 199 22.3 4.48 HVO_1348 probable YjeF family carbohydrate kinase 32.64 1 12 12 37 9.806E7 34.96 29.71 11 18 2116.28 32.64 12 19 478 48.8 4.45 HVO_1816 dihydroorotase 32.63 1 8 8 27 1.324E8 20.17 32.63 8 14 1663.22 32.63 8 13 429 45.4 4.40 HVO_2777 30S ribosomal protein S9 32.58 1 4 4 12 4.603E7 11.79 32.58 4 6 769.84 32.58 4 6 132 14.7 9.74 HVO_A0475 superoxide dismutase (Mn) 32.50 1 0 4 22 1.956E9 24.65 32.50 4 11 1760.12 32.50 4 11 200 22.4 4.45 HVO_1500 1-phosphofructokinase 32.46 1 7 7 21 1.023E8 11.02 29.51 6 10 779.15 32.46 7 11 305 32.0 4.51 HVO_2948 phenylalanine--tRNA ligase alpha subunit 32.46 1 9 9 41 5.301E8 29.25 32.46 9 20 2204.84 32.46 9 21 499 55.1 4.41 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 32.45 1 7 7 28 2.143E8 28.36 32.45 7 14 1735.74 32.45 7 14 265 28.7 4.87 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 32.41 1 6 6 24 3.115E8 14.94 19.37 4 11 1276.56 32.41 6 13 253 26.0 4.60 HVO_1198 UspA domain protein 32.41 1 3 4 11 2.947E8 7.89 32.41 4 6 396.56 32.41 4 5 145 15.6 4.75 HVO_1660 DisA-N domain protein 32.34 1 7 7 27 3.182E8 30.45 32.34 7 14 2055.64 32.34 7 13 269 28.9 4.73 HVO_2712 3'-5' RNA ligase 32.30 1 12 12 43 1.874E8 31.89 30.86 11 21 2405.81 32.30 12 22 486 53.4 4.92 HVO_1148 30S ribosomal protein S15 32.26 1 4 4 14 5.000E7 11.41 32.26 4 6 948.30 32.26 4 8 155 17.5 4.91 HVO_0812 phosphoenolpyruvate synthase 32.19 1 19 19 61 2.243E8 60.57 27.07 17 30 3931.75 29.83 18 31 761 83.1 4.63 HVO_C0069 GFO family oxidoreductase 32.10 1 9 9 51 1.597E8 43.06 32.10 9 26 2793.25 32.10 9 25 324 36.0 5.10 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 31.96 1 3 3 10 1.871E8 6.71 31.96 3 5 654.55 31.96 3 5 97 10.8 4.53 HVO_2225 AstE family protein 31.96 1 6 6 27 4.322E8 28.07 31.96 6 13 1749.73 31.96 6 14 341 36.9 4.53 HVO_1478 transcription initiation factor TFB 31.86 1 5 10 55 4.866E8 53.61 31.86 10 27 4241.12 31.86 10 28 317 35.7 5.47 HVO_2721 amidophosphoribosyltransferase 31.85 1 10 10 40 5.593E8 37.85 31.85 10 20 2267.91 31.85 10 20 493 53.4 4.78 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 31.79 1 6 6 15 5.978E7 10.65 24.64 5 7 807.75 31.79 6 8 280 30.0 4.92 HVO_2708 YfiH family protein 31.68 1 7 7 29 4.362E8 30.42 31.68 7 14 2081.57 31.68 7 15 322 35.4 4.35 HVO_1871 UPF0447 family protein 31.54 1 13 13 49 4.211E8 40.65 28.14 12 24 2919.26 31.54 13 25 501 56.1 4.59 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 16 1.779E9 16.28 31.45 3 8 1239.68 31.45 3 8 124 14.2 5.22 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 31.35 1 6 6 19 1.946E8 11.34 31.35 6 10 672.24 31.35 6 9 386 42.1 4.49 HVO_2908 dihydropteroate synthase 31.13 1 8 8 23 9.135E7 15.32 31.13 8 12 1002.61 31.13 8 11 379 40.8 4.53 HVO_1020 HEAT-PBS family protein 31.03 1 10 10 34 3.169E8 35.50 26.73 9 16 2795.44 31.03 10 18 419 45.5 3.95 HVO_B0018 ParA domain protein 31.01 1 5 5 19 9.389E7 13.36 31.01 5 10 970.12 26.13 4 9 287 31.7 4.74 HVO_2383 DNA repair and recombination protein RadB 31.00 1 6 6 21 1.510E8 20.36 31.00 6 12 1418.62 30.57 5 9 229 24.6 5.02 HVO_1623 conserved hypothetical protein 30.87 1 6 6 32 2.434E8 26.80 30.87 6 16 2025.43 30.87 6 16 298 32.8 4.56 HVO_1488 D-gluconate dehydratase 30.83 1 9 11 80 1.021E9 82.92 30.83 11 40 5188.82 30.83 11 40 412 45.8 4.60 HVO_A0331 D-galactonate dehydratase 30.73 1 7 7 25 2.555E8 27.41 30.73 7 13 1700.60 30.73 7 12 384 42.8 4.83 HVO_1134 conserved hypothetical protein 30.65 1 15 16 64 2.216E8 67.80 29.06 14 31 4273.93 30.65 16 33 757 80.6 4.35 HVO_0214 L-lactate dehydrogenase 30.63 1 10 10 51 1.546E9 41.97 30.63 10 25 3353.15 30.63 10 26 320 34.5 4.49 HVO_0795 transcription initiation factor TFB 30.45 1 6 9 34 3.278E8 31.57 30.45 9 17 2279.48 30.45 9 17 335 37.4 5.59 HVO_0970 ribulose-bisphosphate carboxylase large subunit 30.43 1 11 11 44 1.898E8 42.97 30.43 11 21 2993.52 30.43 11 23 414 43.9 4.59 HVO_B0084 conserved hypothetical protein 30.43 1 2 2 5 3.705E7 0.00 30.43 2 2 145.10 30.43 2 3 138 14.3 4.70 HVO_2879 ornithine cyclodeaminase 30.42 1 7 7 26 2.769E8 17.16 22.89 6 12 1835.73 28.01 6 14 332 34.6 4.45 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 30.34 1 14 14 47 2.543E8 55.74 30.34 14 24 3311.03 30.34 14 23 623 62.1 5.30 HVO_1553 hydroxypyruvate reductase 30.32 1 10 10 29 8.757E7 14.51 30.32 10 15 1240.21 28.51 9 14 442 45.2 4.50 HVO_2496 adenylate kinase 30.29 1 5 5 22 4.947E8 30.73 30.29 5 11 1531.54 30.29 5 11 208 23.1 4.25 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 30.26 1 9 9 54 6.453E8 47.40 24.21 8 28 3223.51 30.26 9 26 347 36.8 4.93 HVO_1804 nicotinate phosphoribosyltransferase 30.15 1 9 9 27 1.957E8 33.37 27.06 8 12 2295.86 30.15 9 15 388 41.1 4.60 HVO_2313 siroheme decarboxylase AhbB 30.03 1 9 9 38 2.372E8 30.95 30.03 9 19 2111.46 30.03 9 19 353 39.6 4.64 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 30.00 1 10 10 48 1.779E8 37.38 27.91 9 24 2621.83 30.00 10 24 430 45.1 4.50 HVO_2347 conserved hypothetical protein 30.00 1 3 3 8 3.729E7 10.21 30.00 3 4 557.25 30.00 3 4 140 15.5 4.37 HVO_0100 NMD3 family protein 29.87 1 7 7 30 9.161E7 29.54 29.87 7 15 1884.93 29.87 7 15 375 41.6 4.46 HVO_2543 50S ribosomal protein L30 29.87 1 3 3 7 4.317E7 1.67 29.87 3 3 220.33 29.87 3 4 154 17.1 4.77 HVO_2947 phenylalanine--tRNA ligase beta subunit 29.82 1 13 13 49 3.222E8 34.10 27.72 11 23 3188.80 29.82 13 26 570 63.3 4.46 HVO_1858 30S ribosomal protein S19e 29.80 1 2 2 3 7.991E7 265.78 29.80 2 3 151 16.7 4.84 HVO_0868 NAD-dependent epimerase/dehydratase 29.79 1 9 9 19 1.061E8 1.92 27.36 8 9 693.57 26.44 8 10 329 36.1 4.55 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 29.79 1 7 7 21 2.234E8 19.97 29.79 7 11 1405.57 28.02 6 10 339 38.1 4.50 HVO_1568 alpha/beta hydrolase fold protein 29.60 1 6 6 21 6.313E7 15.25 24.19 4 8 1299.20 29.60 6 13 277 29.4 4.94 HVO_2564 50S ribosomal protein L3 29.59 1 8 8 40 1.763E8 35.34 29.59 8 20 2484.67 29.59 8 20 338 37.2 6.68 HVO_1657 phosphoribosylamine--glycine ligase 29.44 1 11 11 71 1.275E9 37.49 29.44 11 34 3684.17 29.44 11 37 428 45.5 4.20 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 29.39 1 25 25 139 8.179E8 150.07 27.91 24 68 10763.34 28.84 24 71 1082 117.2 4.32 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 29.32 1 16 16 48 2.517E8 31.79 29.32 15 25 2779.30 25.21 15 23 706 73.3 4.39 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 29.18 1 6 6 35 3.486E8 32.70 29.18 6 18 2262.51 29.18 6 17 377 39.2 4.18 HVO_1235 creatininase 29.17 1 5 5 16 8.547E7 2.15 23.48 4 7 612.89 29.17 5 9 264 29.2 4.84 HVO_C0001 Orc1-type DNA replication protein 29.17 1 10 10 32 1.333E8 26.47 29.17 10 16 1835.34 29.17 10 16 408 45.2 4.97 HVO_0876 methylglyoxal synthase 29.13 1 3 3 6 3.152E7 4.36 29.13 3 3 324.44 29.13 3 3 127 13.9 4.48 HVO_1508 acetolactate synthase large subunit 29.13 1 10 10 48 5.967E8 62.39 29.13 10 24 3586.08 29.13 10 24 587 62.3 4.36 HVO_2690 GFO family oxidoreductase 28.96 1 9 9 48 7.955E8 38.97 28.96 9 24 2702.74 28.96 9 24 366 40.0 4.60 HVO_2781 DNA-directed RNA polymerase subunit D 28.96 1 6 6 40 7.518E8 39.09 28.96 6 20 3175.36 28.96 6 20 259 28.1 4.32 HVO_2536 CHP00300 family protein 28.85 1 6 6 25 8.387E7 14.53 28.85 6 13 909.41 28.85 6 12 416 44.8 4.51 HVO_0658 tRNA pseudouridine(13) synthase TruD 28.73 1 9 9 28 1.293E8 29.07 28.73 9 14 1704.55 28.73 9 14 463 50.6 4.70 HVO_1570 DNA topoisomerase VI subunit A 28.69 1 7 7 29 2.894E8 23.24 25.96 6 13 2157.08 28.69 7 16 366 41.8 4.63 HVO_2793 conserved hypothetical protein 28.57 1 5 5 14 6.988E7 11.05 28.57 5 7 698.96 28.57 5 7 252 27.1 4.46 HVO_2580 L-aspartate oxidase 28.49 1 12 12 52 2.048E8 45.52 27.00 11 25 3693.47 28.49 12 27 537 55.8 4.63 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 28.46 1 13 13 53 3.650E8 45.25 25.53 11 25 2858.07 25.69 12 28 615 67.6 4.88 HVO_2861 conserved hypothetical protein 28.36 1 8 8 40 5.856E8 41.75 28.36 8 20 2708.79 28.36 8 20 275 29.1 4.27 HVO_1698 CBS/parB domain protein 28.30 1 5 6 15 8.209E7 9.43 28.30 6 7 754.83 28.30 6 8 265 29.4 4.92 HVO_1172 NAD-dependent epimerase/dehydratase 28.25 1 9 9 34 8.528E8 34.34 25.71 8 15 3232.17 25.71 8 19 315 34.9 4.34 HVO_0551 DNA mismatch repair protein MutL 28.16 1 12 13 38 7.799E7 34.56 19.59 10 17 2380.04 28.16 13 21 735 78.7 4.50 HVO_1550 acyl-CoA thioester hydrolase 28.13 1 4 4 16 1.167E8 13.02 21.25 3 7 1100.09 28.13 4 9 160 17.6 4.55 HVO_1567 conserved hypothetical protein 28.09 1 4 5 12 1.594E8 4.73 28.09 5 7 540.98 17.02 3 5 235 25.7 4.36 HVO_0357 ACT domain protein 28.04 1 5 5 18 3.417E8 20.33 28.04 5 10 1207.77 28.04 5 8 189 20.2 4.59 HVO_1291 fumarylacetoacetase family protein 27.98 1 5 5 18 4.851E8 21.10 27.98 5 9 1276.80 27.98 5 9 243 26.3 4.55 HVO_1727 TATA-binding transcription initiation factor 27.96 1 6 6 27 8.678E8 24.15 27.96 6 13 2171.59 27.96 6 14 186 19.9 4.36 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 27.85 1 5 5 17 1.967E8 15.02 27.85 5 8 1029.22 27.85 5 9 237 25.4 4.46 HVO_B0001 Orc1-type DNA replication protein 27.80 1 9 10 26 9.988E7 17.47 24.15 9 12 1342.76 27.80 10 14 410 45.8 5.33 HVO_1578 probable NADH dehydrogenase 27.71 1 6 6 20 2.549E8 15.82 27.71 6 9 1121.84 27.71 6 11 397 42.8 4.40 HVO_3014 origin-associated GTP-binding protein OapA 27.70 1 5 5 17 1.153E8 12.92 24.88 4 9 823.75 27.70 5 8 213 24.0 5.01 HVO_1527 glucose-1-phosphate uridylyltransferase 27.57 1 7 7 44 5.811E8 30.03 27.57 7 21 2588.30 27.57 7 23 243 27.5 4.70 HVO_2239 UspA domain protein 27.46 1 4 4 18 2.478E8 18.53 27.46 4 9 1229.52 27.46 4 9 142 15.4 4.16 HVO_1866 uridylate kinase 27.43 1 5 5 25 4.371E8 20.62 27.43 5 13 1676.06 24.47 4 12 237 24.6 4.42 HVO_1547 isoleucine--tRNA ligase 27.42 1 18 18 98 7.319E8 104.73 27.42 18 49 6279.11 27.42 18 49 1043 117.9 4.30 HVO_2227 siroheme decarboxylase AhbA 27.38 1 7 7 23 9.919E7 18.65 27.38 7 12 1274.02 25.07 6 11 347 39.1 4.69 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 27.32 1 3 3 12 2.266E8 5.27 13.66 2 5 676.99 27.32 3 7 183 20.0 4.21 HVO_B0026 probable oxidoreductase (short-chain dehydrogenase family) 27.24 1 4 4 11 5.320E7 8.98 14.40 2 4 573.22 27.24 4 7 257 26.7 4.55 HVO_1967 glucose-6-phosphate isomerase 27.21 1 8 8 36 2.208E8 32.93 27.21 8 18 2565.44 23.72 7 18 430 45.6 4.40 HVO_0573 endonuclease IV 27.15 1 5 5 27 5.399E8 28.87 27.15 5 13 2213.55 27.15 5 14 291 31.4 4.44 HVO_0916 diphthine synthase 27.14 1 6 6 23 2.762E8 13.78 27.14 6 12 1263.32 27.14 6 11 269 29.1 4.54 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 27.12 1 18 18 71 7.740E8 58.34 24.53 16 34 5131.35 27.12 18 37 697 74.5 4.13 HVO_0699 translation initiation factor aIF-2 alpha subunit 27.07 1 6 6 24 4.610E8 29.95 27.07 6 12 1703.00 27.07 6 12 266 29.5 4.46 HVO_0681 DNA topoisomerase I 27.02 1 17 17 58 1.660E8 38.77 26.19 16 29 3273.16 27.02 17 29 840 93.6 4.58 HVO_0879 DUF371 family protein 26.95 1 3 3 13 4.949E7 7.23 26.95 3 6 501.35 26.95 3 7 141 15.3 4.65 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 26.92 1 4 4 18 1.608E8 23.24 26.92 4 9 1285.52 26.92 4 9 208 22.6 4.36 HVO_0122 phosphoglycerate dehydrogenase 26.85 1 6 6 19 1.269E8 16.10 26.85 6 10 1027.28 26.85 6 9 324 35.3 5.35 HVO_2380 AAA-type ATPase (CDC48 subfamily) 26.78 1 17 17 49 1.468E8 36.74 25.98 16 24 2880.89 26.78 17 25 743 81.9 4.82 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 26.77 1 5 5 18 1.425E8 11.62 26.77 5 9 908.32 26.77 5 9 269 28.3 4.49 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 26.71 1 7 7 19 1.165E8 16.60 26.71 7 9 1611.20 26.71 7 10 337 35.9 4.69 HVO_A0133 conserved hypothetical protein 26.71 1 6 6 17 1.361E8 15.81 25.00 5 8 1261.89 26.71 6 9 292 30.8 5.17 HVO_0997 peptidase M24 family protein 26.63 1 6 6 17 8.519E7 16.55 26.63 6 8 1045.39 26.63 6 9 368 39.9 4.49 47132620 keratin 2a [Homo sapiens] 26.60 1 7 13 49 4.027E8 41.91 26.60 13 24 3012.49 26.60 13 25 639 65.4 8.00 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 26.60 1 8 8 30 8.665E7 18.97 26.60 8 15 1533.66 26.60 8 15 406 45.5 5.08 7428712 "keratin 1, type II, cytoskeletal - human" 26.59 1 0 18 92 5.718E8 94.34 26.59 18 45 6890.10 26.59 18 47 643 65.5 6.35 HVO_0972 DUF1628 family protein 26.59 1 2 2 5 7.975E7 585.89 26.59 2 5 173 17.7 4.09 40354192 keratin 10 [Homo sapiens] 26.54 1 0 12 44 1.875E8 42.38 26.54 12 22 3016.31 26.54 12 22 584 58.8 5.16 HVO_1496 phosphotransferase system component I 26.37 1 12 12 48 2.422E8 48.75 26.37 12 24 3152.34 26.37 12 24 565 60.3 4.21 HVO_2784 30S ribosomal protein S13 26.35 1 4 4 18 2.734E8 17.47 26.35 4 9 1140.41 26.35 4 9 167 18.9 5.17 HVO_1562 proteasome beta subunit 26.34 1 6 6 31 3.422E8 26.62 26.34 6 15 1934.78 26.34 6 16 243 26.0 4.63 HVO_0044 acetylglutamate kinase 26.30 1 5 5 20 2.797E8 21.89 26.30 5 10 1699.22 26.30 5 10 327 33.2 4.49 HVO_2759 peptidase M42 family protein 26.27 1 7 7 38 1.096E8 47.69 26.27 7 19 2671.60 26.27 7 19 354 37.0 4.40 HVO_1327 AAA-type ATPase (CDC48 subfamily) 26.22 1 12 13 51 1.698E8 31.03 26.22 13 25 2426.27 24.32 12 26 736 78.1 4.88 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 26.14 1 0 12 44 1.875E8 42.38 26.14 12 22 3016.31 26.14 12 22 593 59.5 5.21 HVO_0048 argininosuccinate lyase 26.02 1 9 9 30 1.205E8 24.33 24.18 8 14 2051.27 26.02 9 16 488 50.8 4.53 HVO_0466 citrate (si)-synthase 25.86 1 8 8 55 6.504E8 70.63 25.86 8 28 4118.00 25.86 8 27 379 41.8 4.55 HVO_2960 dihydrolipoamide S-acyltransferase 25.72 1 13 13 54 2.206E8 59.21 25.72 13 26 3936.02 25.72 13 28 521 54.9 4.40 HVO_1412 diphosphomevalonate decarboxylase 25.62 1 8 8 36 9.401E8 16.17 25.62 8 18 1805.13 25.62 8 18 324 35.4 4.78 HVO_2427 replication factor C large subunit 25.61 1 11 11 34 8.422E7 34.32 23.16 10 17 2068.71 24.18 10 17 488 53.4 4.67 HVO_0358 homoserine dehydrogenase 25.55 1 5 6 24 3.413E8 25.24 18.61 5 11 1588.19 25.55 6 13 317 32.4 4.44 HVO_1079 sulfate adenylyltransferase small subunit 25.54 1 6 6 19 2.216E8 16.44 25.54 6 10 1195.07 25.54 6 9 325 37.5 4.18 HVO_1925 probable GTP-binding protein 25.54 1 6 6 21 1.256E8 5.79 25.54 6 10 891.45 25.54 6 11 325 36.5 4.72 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 25.49 1 7 7 30 3.899E8 20.43 25.49 7 15 1641.65 25.49 7 15 357 39.8 4.41 HVO_2068 "FtsZ family protein, type III" 25.41 1 5 5 22 2.291E8 26.99 25.41 5 11 1968.22 25.41 5 11 370 38.7 4.49 HVO_C0077 sarcosine oxidase 25.32 1 5 5 16 8.025E7 22.67 25.32 5 8 1128.92 25.32 5 8 387 42.9 4.70 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 25.31 1 5 5 22 3.255E8 30.84 25.31 5 11 1861.62 25.31 5 11 324 33.6 3.99 HVO_2108 IclR family transcription regulator 25.30 1 4 4 7 3.396E7 0.00 12.25 2 2 250.64 25.30 4 5 253 28.0 5.74 HVO_1048 phosphoribosylformylglycinamidine synthase 2 25.21 1 12 12 73 7.905E8 85.97 24.22 11 35 5666.94 25.21 12 38 702 72.9 4.18 HVO_2951 tryptophan--tRNA ligase 25.14 1 10 10 34 1.421E8 16.75 25.14 10 17 1409.58 25.14 10 17 529 59.1 4.53 HVO_2717 alanine--tRNA ligase 25.13 1 9 9 35 1.617E8 32.44 20.60 7 16 2484.00 25.13 9 19 398 41.6 4.39 >sp|TRYP_PIG| 25.11 1 4 4 65 1.856E10 71.22 25.11 4 32 5003.07 25.11 4 33 231 24.4 7.18 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 25.08 1 11 11 36 1.233E8 26.90 23.56 10 17 2311.94 25.08 11 19 658 72.1 4.70 HVO_1979 tRNA pseudouridine synthase Pus10 25.06 1 8 8 34 3.724E8 29.87 23.42 7 17 2123.06 17.33 7 17 427 46.9 4.39 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 25.05 1 10 10 27 8.663E7 23.28 23.97 9 13 1724.32 25.05 10 14 459 50.5 4.63 HVO_0034 acyl-CoA thioester hydrolase 25.00 1 4 4 28 2.253E8 30.40 25.00 4 14 2223.60 25.00 4 14 164 18.3 4.65 HVO_1581 cytidine deaminase 25.00 1 3 3 5 2.251E7 1.79 20.00 2 2 235.66 25.00 3 3 140 15.0 4.22 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 25.00 1 3 3 10 1.174E8 14.15 25.00 3 5 790.54 25.00 3 5 184 19.8 5.30 HVO_0854 DNA double-strand break repair ATPase Rad50 24.97 1 17 17 56 1.318E8 56.70 23.63 16 26 3528.85 24.97 17 30 893 100.0 4.58 HVO_0123 signal recognition particle 54K protein 24.95 1 11 11 48 2.696E8 40.43 22.80 10 23 3111.38 24.95 11 25 465 50.9 4.50 HVO_1725 Orc1-type DNA replication protein 24.94 1 7 8 17 4.931E7 7.33 19.45 6 7 896.95 24.94 8 10 401 44.5 5.19 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 24.93 1 9 9 69 1.553E9 67.41 17.65 8 34 4160.91 24.93 9 35 357 40.3 4.40 HVO_1531 UDP-glucose 6-dehydrogenase 24.88 1 10 10 48 2.121E8 41.55 24.88 10 24 2978.63 24.88 10 24 430 45.9 4.50 HVO_0889 FAD-dependent oxidoreductase 24.77 1 3 3 8 8.582E7 6.33 24.77 3 4 660.72 24.77 3 4 214 21.8 3.89 HVO_1453 glutamate dehydrogenase (NADP) 24.70 1 8 9 29 1.820E8 16.83 21.10 7 13 1571.43 24.70 9 16 417 45.7 4.49 HVO_0042 acetylornithine deacetylase 24.67 1 8 8 27 3.950E8 11.97 24.67 8 13 1246.16 24.67 8 14 381 41.0 4.34 HVO_0769 TRAM domain protein 24.63 1 4 4 11 5.724E7 7.45 24.63 4 5 632.56 24.63 4 6 134 14.8 4.32 HVO_2205 arNOG06768 family NADH-binding domain protein 24.58 1 5 5 20 7.656E7 24.52 24.58 5 10 1422.65 24.58 5 10 301 32.0 5.00 HVO_1510 2-isopropylmalate synthase 24.55 1 8 8 32 1.317E9 41.10 22.73 7 16 2505.22 24.55 8 16 440 47.7 4.82 HVO_1711 glucoamylase 24.49 1 30 30 106 1.463E8 76.13 24.49 30 52 6002.41 24.49 30 54 1511 166.1 4.64 HVO_1187 conserved hypothetical protein 24.48 1 3 3 11 3.483E7 5.92 24.48 3 6 465.89 24.48 3 5 143 16.4 4.86 HVO_0019 probable S-adenosylmethionine-dependent methyltransferase (homolog to 24-sterol C-methyltransferase) 24.34 1 3 3 16 4.841E7 10.56 24.34 3 8 769.35 24.34 3 8 226 25.6 4.64 HVO_2156 UspA domain protein 24.25 1 6 6 24 4.046E8 25.77 24.25 6 11 2120.27 24.25 6 13 301 31.6 4.69 HVO_B0114 IclR family transcription regulator 24.21 1 6 6 18 3.146E7 6.11 24.21 6 9 731.04 24.21 6 9 252 28.4 5.44 HVO_1073 ThiJ/PfpI family protein 24.11 1 4 4 12 1.115E8 13.36 24.11 4 6 690.24 24.11 4 6 224 23.9 4.12 HVO_2562 50S ribosomal protein L23 24.10 1 2 2 6 3.596E7 5.91 24.10 2 3 539.12 24.10 2 3 83 9.4 5.48 HVO_1683 4-alpha-glucanotransferase 23.99 1 9 9 21 6.264E7 8.80 23.99 9 11 647.70 21.98 8 10 496 56.3 4.45 HVO_2761 mevalonate kinase 23.98 1 5 5 19 6.860E7 19.46 23.98 5 10 869.68 18.26 4 9 367 38.2 4.31 HVO_0670 glutathione S-transferase 23.93 1 6 7 15 1.632E8 7.78 19.33 6 8 648.12 19.02 5 7 326 38.1 4.56 HVO_2716 acyl-CoA dehydrogenase 23.88 1 6 6 23 6.859E7 24.78 23.88 6 11 1468.21 23.88 6 12 381 41.3 4.65 HVO_2008 archaeosine synthase 23.76 1 11 11 40 3.272E8 25.66 23.76 11 21 2158.63 22.56 10 19 585 64.9 4.81 HVO_0054 glycine--tRNA ligase 23.74 1 9 9 35 1.226E9 40.18 18.86 7 16 2913.06 23.74 9 19 594 64.9 4.21 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 23.61 1 5 5 25 1.447E8 12.64 23.61 5 12 1072.14 23.61 5 13 305 34.1 4.91 HVO_2998 homoserine O-acetyltransferase 23.61 1 5 5 20 7.176E7 22.25 23.61 5 10 1396.01 23.61 5 10 415 44.8 4.69 HVO_1175 DUF2110 family protein 23.56 1 5 5 26 6.813E8 27.86 23.56 5 13 1962.60 23.56 5 13 225 24.4 4.63 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 23.55 1 7 7 25 1.867E8 26.88 20.35 6 11 2152.99 23.55 7 14 344 39.1 4.73 HVO_0697 PAC2 family protein 23.53 1 3 3 20 2.829E8 25.47 23.53 3 10 1752.27 23.53 3 10 255 27.4 4.08 HVO_2266 hypothetical protein 23.53 1 10 10 37 1.916E8 22.60 23.53 10 18 1984.25 23.53 10 19 493 56.7 4.54 HVO_1918 probable metallo-beta-lactamase family hydrolase 23.51 1 3 3 7 4.009E7 7.15 23.51 3 4 363.11 23.51 3 3 302 34.0 4.55 HVO_2790 ATP-binding protein Mrp 23.41 1 5 5 21 2.465E8 24.04 23.41 5 10 1546.65 23.41 5 11 346 36.8 4.50 HVO_1879 enoyl-CoA hydratase 23.38 1 3 3 6 3.060E7 2.39 15.58 2 2 233.36 23.38 3 4 231 24.3 5.21 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 23.06 1 9 9 30 1.187E8 33.49 23.06 9 15 2103.65 23.06 9 15 516 56.7 4.89 HVO_0087 porphobilinogen synthase 22.94 1 5 5 18 5.196E7 13.92 22.94 5 9 801.17 14.98 4 9 327 35.3 4.72 HVO_1625 conserved hypothetical protein 22.94 1 12 12 36 1.137E8 39.98 20.34 11 18 2687.57 22.17 11 18 654 70.1 4.04 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 22.88 1 8 8 27 2.285E8 19.14 22.88 8 14 1729.00 20.59 7 13 612 67.3 4.16 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 22.83 1 3 3 16 5.904E7 12.91 22.83 3 8 1111.72 22.83 3 8 219 22.4 4.06 HVO_2168 AAA-type ATPase (MoxR subfamily) 22.80 1 5 5 14 9.031E7 13.39 17.02 3 6 855.83 22.80 5 8 329 35.9 4.54 HVO_1174 transcription initiation factor TFE 22.73 1 2 2 6 7.539E7 7.46 22.73 2 3 413.95 22.73 2 3 176 20.6 4.23 HVO_A0328 2-keto-3-deoxygluconate kinase 22.64 1 5 6 16 2.242E8 9.47 22.64 6 8 647.81 22.64 6 8 318 34.0 4.60 HVO_0470 threonine synthase 22.62 1 5 5 15 7.863E7 7.35 22.62 5 7 674.59 22.62 5 8 367 39.2 4.59 HVO_0552 DNA mismatch repair protein MutS 22.62 1 16 16 47 1.997E8 36.75 19.16 14 23 2710.40 21.65 15 24 924 99.2 4.65 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 22.56 1 5 5 12 7.101E7 11.74 22.56 5 6 875.39 22.56 5 6 328 36.1 4.67 HVO_0360 30S ribosomal protein S10 22.55 1 2 2 8 1.432E8 9.94 22.55 2 4 624.89 22.55 2 4 102 11.5 4.88 HVO_1847 oligoendopeptidase PepF 22.54 1 12 12 46 1.386E8 38.76 22.54 12 23 2688.72 22.54 12 23 599 68.5 4.41 HVO_1391 NUDIX family hydrolase 22.52 1 3 3 8 4.516E7 9.43 22.52 3 4 591.19 22.52 3 4 151 17.4 5.01 HVO_1878 NAD synthase 22.46 1 6 6 21 1.620E8 18.79 22.46 6 11 1143.47 19.57 5 10 276 29.6 4.37 HVO_B0127 oxidoreductase (luciferase family protein) 22.40 1 5 5 16 6.908E7 16.01 22.40 5 9 760.78 17.35 4 7 317 35.7 4.60 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 22.39 1 5 5 20 6.211E7 18.45 22.39 5 10 1170.67 22.39 5 10 268 27.9 4.87 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 22.38 1 4 4 18 1.977E8 15.46 18.41 3 8 1324.95 22.38 4 10 277 30.6 4.30 HVO_1503 3-isopropylmalate dehydratase small subunit 22.28 1 4 4 23 2.429E8 12.99 22.28 4 11 1052.50 22.28 4 12 202 22.0 4.15 HVO_B0115 fumarylacetoacetase family protein 22.26 1 5 5 16 2.003E8 17.54 22.26 5 9 1238.98 20.49 4 7 283 30.3 4.21 HVO_1823 UspA domain protein 22.22 1 3 3 6 2.450E7 6.47 22.22 3 3 201.87 22.22 3 3 153 16.4 4.60 HVO_1989 tRNA (pseudouridine(54)-N(1))-methyltransferase 22.22 1 2 2 10 9.683E7 10.75 22.22 2 5 567.28 22.22 2 5 198 21.9 4.79 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 22.22 1 7 7 26 3.941E8 11.61 19.17 6 12 1378.98 22.22 7 14 360 38.5 4.45 HVO_0894 acyl-CoA synthetase 22.21 1 5 11 28 1.134E8 19.11 20.69 10 13 1502.87 20.69 10 15 662 74.3 4.48 HVO_2906 tRNA (cytidine/uridine-2'-O-)-methyltransferase 22.18 1 4 4 8 2.905E7 5.06 22.18 4 4 445.98 22.18 4 4 275 30.6 4.58 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 22.13 1 5 5 17 6.715E7 2.13 22.13 5 9 483.39 19.54 4 8 348 36.7 4.69 HVO_0768 radical SAM domain protein 22.12 1 7 7 14 5.909E7 4.53 14.69 5 6 462.70 22.12 7 8 565 62.0 4.84 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 22.12 1 24 24 98 2.513E8 76.95 22.12 24 49 5393.55 22.12 24 49 1284 141.2 4.35 HVO_0220 ATP-dependent DNA helicase MCM 22.08 1 14 14 43 6.433E7 32.89 22.08 14 23 2476.35 19.94 12 20 702 78.8 4.73 HVO_0429 archaemetzincin 21.97 1 2 3 9 8.194E7 4.24 21.97 3 5 447.78 17.92 2 4 173 19.3 6.54 HVO_1656 YyaL family protein 21.76 1 13 13 48 6.171E7 18.33 20.48 12 24 2118.81 18.07 12 24 703 77.3 4.49 HVO_0867 HD family hydrolase 21.74 1 4 4 22 1.148E8 19.31 21.74 4 11 1233.14 21.74 4 11 230 26.2 4.78 HVO_2421 probable DNA-binding protein 21.70 1 3 3 6 6.285E7 1.99 21.70 3 3 229.02 21.70 3 3 235 25.8 4.89 HVO_2001 tRNA-guanine(15) transglycosylase 21.51 1 7 7 20 1.732E8 16.98 21.51 7 10 1112.98 21.51 7 10 516 56.3 4.59 HVO_2707 GFO family oxidoreductase 21.51 1 6 7 23 4.860E8 27.76 19.62 6 11 1497.54 21.51 7 12 372 41.0 4.55 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 21.41 1 7 8 30 7.502E7 13.08 19.06 7 15 1110.12 21.41 8 15 383 42.0 4.49 HVO_2662 homolog to lactoylglutathione lyase 21.28 1 6 6 22 1.000E8 21.81 21.28 6 11 1359.21 21.28 6 11 329 36.5 4.48 HVO_2706 translation initiation factor aIF-2B delta subunit 21.28 1 5 5 26 2.941E8 15.46 21.28 5 13 1375.30 21.28 5 13 282 30.7 4.42 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 21.27 1 6 6 15 8.648E7 11.39 21.27 6 8 946.22 18.55 5 7 442 46.9 4.58 HVO_2688 TrmB family transcription regulator 21.25 1 6 7 27 4.761E8 23.90 19.83 6 13 2006.94 21.25 7 14 353 39.3 4.58 HVO_2229 flavin-containing amine-oxidoreductase 21.22 1 5 6 17 6.097E7 11.89 18.60 5 8 617.18 21.22 6 9 344 37.9 4.92 HVO_2554 50S ribosomal protein L14 21.21 1 4 4 14 1.616E8 7.88 21.21 4 7 763.49 21.21 4 7 132 14.2 9.76 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 21.14 1 4 4 10 4.143E7 8.51 21.14 4 5 497.52 21.14 4 5 175 18.8 4.63 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 21.09 1 2 2 10 8.025E7 10.56 21.09 2 5 851.63 21.09 2 5 128 13.0 4.31 HVO_2648 phosphoglycerate dehydrogenase 21.00 1 5 5 16 1.043E8 12.21 21.00 5 8 923.42 21.00 5 8 319 34.2 4.64 HVO_B0182 deoxyhypusine synthase 20.99 1 6 6 24 1.195E8 14.98 20.99 6 12 1230.16 20.99 6 12 324 35.6 4.30 HVO_0561 50S ribosomal protein L15e 20.92 1 4 4 12 1.016E8 8.21 20.92 4 6 799.44 20.92 4 6 196 22.5 11.15 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 20.90 1 2 2 2 2.770E7 270.55 20.90 2 2 134 13.9 4.55 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 20.82 1 6 6 20 1.833E8 7.52 20.82 6 10 895.47 20.82 6 10 365 39.0 4.61 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 20.80 1 6 6 19 6.817E7 8.69 17.13 5 9 1113.50 20.80 6 10 327 36.0 4.73 HVO_1937 "probable 5,10-methylenetetrahydrofolate reductase" 20.73 1 3 3 5 5.120E7 1.65 9.15 2 2 149.52 20.73 3 3 328 34.5 4.63 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 6 3.537E7 6.10 20.71 2 3 416.43 20.71 2 3 140 16.0 5.57 HVO_0179 Lrp/AsnC family transcription regulator / TrkA domain protein 20.69 1 4 4 11 7.901E7 10.15 20.69 4 6 603.26 20.69 4 5 261 28.0 4.58 HVO_0826 peptidase M42 family protein 20.69 1 4 4 16 8.145E7 17.31 20.69 4 8 1179.39 20.69 4 8 348 37.7 4.54 HVO_1139 squalene synthase 20.67 1 3 3 10 1.406E8 10.83 20.67 3 5 634.27 20.67 3 5 358 39.7 4.54 HVO_C0042 helicase domain protein 20.64 1 22 22 71 1.698E8 58.09 20.09 21 35 4217.65 20.64 22 36 1274 144.4 4.67 HVO_2412 Lrp/AsnC family transcription regulator 20.50 1 3 3 10 5.505E7 6.07 20.50 3 5 562.78 20.50 3 5 161 17.7 4.55 HVO_2965 phosphoserine phosphatase 20.47 1 3 3 8 4.939E7 4.66 20.47 3 4 450.93 20.47 3 4 215 23.2 4.51 HVO_1575 arginase 20.40 1 4 4 14 1.498E8 6.82 20.40 4 7 627.25 20.40 4 7 299 31.0 4.58 HVO_2888 homolog to elongator complex protein ELP3 20.36 1 10 10 21 6.709E7 17.49 17.82 9 10 1101.35 19.09 9 11 550 62.6 5.01 HVO_2255 conserved hypothetical protein 20.34 1 4 4 6 5.300E7 1.82 13.98 3 3 237.43 15.68 3 3 236 27.7 5.60 HVO_0733 transcription initiation factor TFB 20.25 1 2 7 28 4.137E8 24.33 20.25 7 14 1779.59 20.25 7 14 326 37.2 6.00 HVO_B0382 TATA-binding transcription initiation factor 20.21 1 3 3 10 7.659E7 6.78 20.21 3 5 568.27 20.21 3 5 188 20.1 4.12 HVO_2555 30S ribosomal protein S17 20.18 1 2 2 6 7.248E7 4.46 20.18 2 3 388.58 20.18 2 3 114 12.7 4.81 HVO_2298 UPF0135 family protein 20.16 1 2 2 2 2.698E7 109.57 20.16 2 2 253 26.5 4.37 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 20.06 1 6 6 30 1.642E8 26.43 20.06 6 15 1942.02 20.06 6 15 349 37.0 4.70 HVO_0402 DUF124 family protein 20.00 1 3 3 9 1.323E8 5.69 20.00 3 4 423.31 20.00 3 5 225 24.0 4.58 HVO_1098 diaminopimelate decarboxylase 20.00 1 7 7 24 1.910E8 15.83 20.00 7 12 1007.04 16.87 6 12 415 44.4 5.02 HVO_1129 conserved hypothetical protein 20.00 1 5 5 15 1.792E8 17.39 20.00 5 7 972.92 20.00 5 8 390 43.0 4.44 HVO_1501 DeoR family transcription regulator GlpR 20.00 1 4 4 12 5.013E7 13.26 20.00 4 6 872.04 20.00 4 6 255 28.0 4.97 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 20.00 1 6 6 17 8.512E7 12.50 20.00 6 9 769.45 20.00 6 8 345 36.9 4.68 HVO_2702 alpha/beta hydrolase fold protein 20.00 1 4 4 16 1.026E8 4.92 20.00 4 8 702.69 20.00 4 8 260 28.0 4.53 HVO_0120 signal recognition particle receptor FtsY 19.96 1 6 6 18 7.430E7 18.74 19.96 6 9 1233.42 19.96 6 9 456 48.2 4.17 HVO_2614 uridine phosphorylase 19.83 1 4 4 18 6.261E8 15.22 19.83 4 8 1076.76 19.83 4 10 242 25.8 4.30 HVO_1299 HTH domain protein 19.65 1 3 3 13 5.132E7 11.55 19.65 3 7 754.97 19.65 3 6 173 18.9 4.84 HVO_2467 NADPH:quinone reductase 19.63 1 5 5 26 1.894E8 21.73 19.63 5 13 1760.49 19.63 5 13 321 33.0 4.51 HVO_2453 anthranilate synthase component II 19.61 1 2 2 6 6.886E7 1.76 19.61 2 3 199.38 19.61 2 3 204 21.8 4.55 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 19.55 1 4 4 15 5.709E7 6.56 19.55 4 7 695.10 19.55 4 8 266 29.7 4.32 HVO_0818 threonine synthase 19.54 1 7 7 30 2.488E8 22.39 19.54 7 15 1505.07 19.54 7 15 389 40.8 4.31 HVO_2945 valine--tRNA ligase 19.54 1 15 15 67 6.097E8 67.44 17.13 13 33 4805.18 19.54 15 34 870 98.9 4.36 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 19.40 1 7 7 24 1.388E8 17.64 19.40 7 12 1247.16 19.40 7 12 464 53.1 4.54 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 25 9.388E8 20.19 19.31 5 12 1793.81 19.31 5 13 378 39.7 4.67 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 19.30 1 7 7 34 5.523E8 18.48 19.30 7 17 1716.16 19.30 7 17 373 40.2 4.44 HVO_0194 Orc1-type DNA replication protein 19.25 1 8 8 23 5.275E7 5.86 15.51 7 11 982.92 19.25 8 12 374 42.2 4.94 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 19.25 1 20 20 57 1.288E8 37.05 16.93 18 28 2996.82 18.20 19 29 1335 150.5 4.60 HVO_1948 NUDIX family hydrolase 19.25 1 3 3 5 1.932E7 2.08 13.90 2 2 292.50 19.25 3 3 187 20.9 4.45 HVO_B0117 conserved hypothetical protein 19.23 1 3 4 11 2.962E7 7.24 16.35 3 5 653.99 19.23 4 6 208 23.3 4.58 HVO_2153 probable copper-containing oxidoreductase 19.22 1 6 6 28 1.690E8 12.65 19.22 6 13 1315.32 19.22 6 15 385 42.1 5.82 HVO_A0307 Lrp/AsnC family transcription regulator 19.21 1 3 3 12 1.163E8 8.22 19.21 3 6 776.48 19.21 3 6 177 19.4 4.39 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 19.15 1 5 5 24 1.088E8 19.84 19.15 5 12 1718.15 19.15 5 12 329 36.3 4.49 HVO_1289 OsmC domain protein 18.94 1 2 2 30 8.288E8 48.12 18.94 2 15 3835.94 18.94 2 15 132 14.2 3.85 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 18.93 1 9 9 29 1.162E8 29.82 18.93 9 14 1732.88 18.93 9 15 634 66.1 4.54 HVO_A0002 conserved hypothetical protein 18.75 1 2 2 8 3.291E7 7.78 18.75 2 4 650.60 18.75 2 4 192 20.7 4.02 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 18.74 1 5 5 12 4.613E7 9.38 18.74 5 6 794.12 18.74 5 6 475 49.3 4.49 HVO_1356 sensor box histidine kinase 18.73 1 6 6 17 1.230E8 13.27 18.73 6 9 727.90 16.36 5 8 550 61.1 4.60 HVO_1957 proteasome-activating nucleotidase 18.69 1 6 7 20 1.500E8 12.96 18.69 7 9 1107.77 18.69 7 11 412 45.6 4.48 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 18.65 1 6 6 13 4.967E7 5.05 18.65 6 7 549.98 18.65 6 6 386 40.0 4.68 HVO_0326 CTP-dependent riboflavin kinase 18.57 1 3 3 8 8.161E7 10.01 18.57 3 4 651.23 18.57 3 4 237 25.9 4.55 HVO_B0130 DUF296 family protein 18.52 1 2 2 8 1.573E8 5.69 18.52 2 4 530.70 18.52 2 4 135 14.8 4.41 HVO_2912 ThiJ/PfpI domain protein 18.41 1 2 2 8 8.371E7 8.91 18.41 2 4 543.74 18.41 2 4 201 20.9 4.36 HVO_1718 "6-carboxy-5,6,7,8-tetrahydropterin synthase" 18.35 1 2 2 8 6.754E7 12.09 18.35 2 4 668.31 18.35 2 4 158 17.1 4.78 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 19 2.344E8 20.22 18.29 4 10 1519.38 18.29 4 9 257 26.8 4.01 HVO_2952 tRNA-splicing endonuclease 18.29 1 4 4 10 8.859E7 8.17 18.29 4 5 408.85 18.29 4 5 339 37.4 4.74 HVO_0234 conserved hypothetical protein 18.18 1 3 3 10 4.080E7 15.69 18.18 3 5 774.22 18.18 3 5 275 28.1 4.48 HVO_2456 anthranilate phosphoribosyltransferase 18.13 1 4 4 11 1.912E8 11.61 18.13 4 6 640.91 18.13 4 5 331 33.8 4.35 HVO_1716 7-cyano-7-deazaguanine synthase 18.03 1 4 4 12 6.493E7 6.28 18.03 4 7 380.49 13.52 3 5 244 26.8 4.42 HVO_0719 transcription elongation factor Spt5/NusG 18.00 1 3 3 6 4.988E7 3.86 14.00 2 2 428.67 18.00 3 4 150 16.3 4.50 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 17.99 1 5 5 14 1.175E8 9.18 17.99 5 7 675.65 15.87 4 7 378 39.8 4.45 HVO_1337 rpa-associated protein 17.98 1 8 8 29 2.557E8 29.72 17.98 8 14 1686.19 17.98 8 15 623 64.8 3.68 HVO_2600 methionyl aminopeptidase 17.91 1 6 6 19 2.117E8 12.74 13.85 5 9 1058.89 15.88 5 10 296 32.3 4.41 HVO_0712 shikimate dehydrogenase (nonfunctional) 17.84 1 3 3 4 4.105E7 6.70 17.84 3 4 269 27.7 4.65 HVO_0569 RIO-type serine/threonine protein kinase 17.82 1 4 4 10 4.503E7 2.84 17.82 4 5 410.28 17.82 4 5 303 34.4 4.94 HVO_2873 flap endonuclease Fen1 17.79 1 4 4 11 5.594E7 8.46 17.79 4 5 701.72 17.79 4 6 326 36.4 4.40 HVO_0407 conserved hypothetical protein 17.74 1 2 2 6 4.894E7 3.59 17.74 2 3 245.76 17.74 2 3 124 13.4 4.44 HVO_0931 UspA domain protein 17.61 1 1 2 6 8.904E7 8.11 17.61 2 3 479.45 17.61 2 3 142 15.2 4.46 HVO_2639 DUF1611 family protein 17.60 1 4 4 26 1.265E8 27.50 17.60 4 13 1630.88 17.60 4 13 341 36.3 4.44 HVO_B0143 receiver/sensor box histidine kinase 17.59 1 7 7 20 6.086E7 18.46 17.59 7 10 1233.16 17.59 7 10 597 66.0 4.41 HVO_1895 KEOPS complex subunit Kae1/Bud32 17.57 1 7 7 20 1.070E8 20.12 17.57 7 10 1106.00 17.57 7 10 552 59.0 5.07 HVO_A0586 sugar nucleotidyltransferase 17.52 1 5 5 18 6.699E7 11.78 17.52 5 9 1092.06 17.52 5 9 411 43.7 4.69 HVO_0600 ACT domain protein 17.51 1 3 3 8 6.044E7 4.33 17.51 3 4 318.18 17.51 3 4 177 19.2 4.44 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 17.49 1 4 4 14 7.091E7 18.45 17.49 4 7 1113.28 17.49 4 7 446 47.9 4.39 HVO_B0256 aldehyde ferredoxin oxidoreductase 17.48 1 6 6 13 2.746E7 9.01 13.15 5 6 554.49 17.48 6 7 555 59.9 4.55 HVO_A0547 DUF1028 family protein 17.42 1 4 4 7 4.335E7 2.64 10.81 3 3 369.03 17.42 4 4 333 35.2 4.16 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 17.30 1 3 3 7 3.595E7 4.24 17.30 3 4 172.11 10.55 2 3 237 26.2 4.70 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 17.12 1 4 4 17 5.817E7 9.24 17.12 4 8 721.65 17.12 4 9 438 46.4 4.58 HVO_2636 PspA domain protein 17.03 1 4 4 14 1.733E7 14.05 17.03 4 7 1101.86 17.03 4 7 276 30.9 4.61 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 17.02 1 7 7 24 1.858E8 18.60 17.02 7 12 1333.67 17.02 7 12 423 43.9 4.31 HVO_0469 AstE family protein 16.98 1 4 4 12 1.131E8 13.25 16.98 4 6 941.78 16.98 4 6 318 33.9 5.85 HVO_A0486 hydrogenase expression/formation protein 16.96 1 3 3 12 6.828E7 12.93 16.96 3 6 871.08 16.96 3 6 336 33.8 4.06 HVO_1268 conserved hypothetical protein 16.88 1 3 3 8 4.132E7 6.00 16.88 3 4 450.35 9.70 2 4 237 26.4 5.21 HVO_2189 phosphoribosylformylglycinamidine synthase component PurS 16.87 1 1 2 2 6.408E7 0.00 16.87 2 2 83 9.3 4.50 HVO_2504 probable oxidoreductase (short-chain dehydrogenase family) 16.81 1 3 3 8 9.668E6 4.06 16.81 3 4 347.09 16.81 3 4 232 24.8 4.59 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 16.78 1 7 7 16 9.003E7 6.05 15.75 6 8 719.90 12.67 6 8 584 63.3 4.79 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 16.54 1 5 5 9 9.357E7 6.34 5.25 2 3 540.46 16.54 5 6 381 40.5 4.51 HVO_2501 alpha/beta hydrolase fold protein 16.46 1 4 4 14 4.591E7 7.95 16.46 4 7 644.39 16.46 4 7 316 35.3 5.72 HVO_1413 probable NADH dehydrogenase 16.45 1 5 5 11 5.828E7 7.53 14.06 4 5 749.56 16.45 5 6 377 39.7 4.67 HVO_B0055 conserved hypothetical protein 16.44 1 5 5 14 1.176E8 4.54 16.44 5 7 715.23 16.44 5 7 225 23.9 4.69 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 16.39 1 3 3 12 7.452E7 11.50 16.39 3 6 559.39 16.39 3 6 305 32.7 4.56 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 16.33 1 2 2 6 6.168E7 6.11 16.33 2 3 317.92 16.33 2 3 294 32.5 4.75 HVO_B0375 Spo0M family protein 16.33 1 2 2 6 2.429E7 7.75 16.33 2 3 433.74 16.33 2 3 245 27.2 4.35 HVO_1058 TrkA domain protein 16.18 1 6 6 23 1.388E8 15.36 14.38 5 11 1108.82 16.18 6 12 445 47.7 4.35 HVO_0056 conserved hypothetical protein 16.15 1 2 2 4 2.396E7 1.61 16.15 2 2 126.62 16.15 2 2 192 20.9 4.16 HVO_2763 homolog to ribonuclease Z 16.13 1 3 3 15 5.920E7 5.37 16.13 3 8 374.87 16.13 3 7 248 26.6 4.53 HVO_A0452 UspA domain protein 16.04 1 3 3 8 2.438E7 2.43 16.04 3 4 283.88 16.04 3 4 293 31.3 4.63 HVO_1375 O-succinylbenzoic acid--CoA ligase 15.96 1 7 7 14 5.248E7 12.30 15.96 7 7 775.46 15.96 7 7 614 64.7 4.28 HVO_0853 DNA double-strand break repair protein Mre11 15.87 1 5 5 15 9.042E7 6.51 14.51 4 7 651.71 15.87 5 8 441 48.1 4.39 HVO_1899 DNA-directed RNA polymerase subunit E 15.79 1 3 3 13 8.522E7 8.43 15.79 3 6 748.44 15.79 3 7 190 21.0 4.74 HVO_0001 Orc1-type DNA replication protein 15.78 1 7 8 24 5.187E7 17.22 15.78 8 12 1498.68 15.78 8 12 564 62.1 4.39 HVO_0190 TIGR00268 family protein 15.77 1 4 4 12 2.351E7 8.83 15.77 4 6 562.69 15.77 4 6 298 32.5 4.60 HVO_B0060 precorrin-4 C11-methyltransferase 15.77 1 3 3 14 1.037E8 8.91 15.77 3 7 443.16 15.77 3 7 279 29.7 4.22 HVO_0760 "probable glycosyltransferase, type 2" 15.76 1 6 6 18 5.024E7 7.90 15.76 6 9 978.20 15.76 6 9 368 40.7 4.82 HVO_A0601 NosL family protein 15.76 1 2 2 2 5.132E6 1.76 15.76 2 2 203 21.5 4.60 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 15.60 1 3 3 12 6.078E7 5.51 15.60 3 6 447.47 15.60 3 6 327 36.2 4.63 HVO_0328 NAD-dependent epimerase/dehydratase 15.54 1 2 2 4 2.966E7 2.63 15.54 2 2 98.29 15.54 2 2 296 31.7 5.07 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 15.52 1 4 4 14 3.817E7 16.74 15.52 4 7 1118.74 15.52 4 7 406 43.1 4.60 HVO_0639 AAA-type ATPase (MoxR subfamily) 15.51 1 4 4 15 4.780E7 2.66 15.51 4 7 643.94 15.51 4 8 316 34.7 4.89 HVO_2072 S-layer glycoprotein 15.48 1 5 5 122 1.606E9 99.06 15.48 5 62 4165.74 15.48 5 60 827 85.1 3.65 HVO_B0324 conserved hypothetical protein 15.37 1 6 6 14 3.448E7 8.67 15.37 6 7 593.20 15.37 6 7 449 48.0 4.58 HVO_2581 quinolinate synthase A 15.32 1 5 5 20 1.731E8 17.15 15.32 5 10 1175.67 15.32 5 10 385 42.0 4.41 HVO_A0498 conserved hypothetical protein 15.30 1 5 5 14 6.020E7 3.97 15.30 5 7 488.89 13.72 4 7 379 42.7 4.55 HVO_1629 conserved hypothetical protein 15.25 1 6 6 20 7.070E7 19.28 15.25 6 10 1117.45 15.25 6 10 531 56.3 4.69 HVO_0195 ribose-5-phosphate isomerase 15.22 1 3 3 10 1.175E8 7.21 15.22 3 5 564.00 15.22 3 5 230 23.2 4.54 HVO_A0087 fumarylacetoacetase family protein 15.22 1 3 3 12 2.611E8 16.17 15.22 3 6 961.81 15.22 3 6 289 32.0 4.21 HVO_A0092 acyl-CoA dehydrogenase 15.22 1 5 5 13 4.415E7 9.58 13.39 4 6 735.11 15.22 5 7 381 42.2 4.83 HVO_0228 ParA domain protein 14.98 1 3 3 6 1.210E8 4.44 7.29 2 3 376.98 11.74 2 3 247 24.6 4.16 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 14.94 1 3 3 12 6.187E7 1.97 14.94 3 6 492.37 14.94 3 6 261 27.0 4.44 HVO_1087 UspA domain protein 14.89 1 3 3 8 6.991E7 7.14 14.89 3 4 619.71 14.89 3 4 141 15.2 4.98 HVO_3000 DNA ligase (NAD) 14.88 1 8 8 23 3.750E8 16.44 14.88 8 12 1210.58 13.16 7 11 699 75.8 4.50 HVO_1296 probable adenylate kinase 14.79 1 2 2 6 2.976E7 1.68 14.79 2 3 241.14 14.79 2 3 169 18.7 4.44 HVO_A0228 5'-nucleotidase SurE 14.78 1 2 2 10 3.074E7 14.06 14.78 2 5 1061.59 14.78 2 5 291 31.5 4.59 HVO_0787 indole-3-glycerol-phosphate synthase 14.74 1 3 3 6 4.980E7 5.01 14.74 3 3 258.09 14.74 3 3 251 26.7 4.44 HVO_2665 HpcH/HpaI aldolase family protein 14.72 1 4 4 12 8.099E7 10.27 14.72 4 6 618.08 14.72 4 6 265 28.3 4.50 HVO_1579 uridine phosphorylase 14.71 1 2 2 7 8.528E7 7.10 14.71 2 4 337.99 14.71 2 3 272 29.0 4.64 HVO_1485 conserved hypothetical protein 14.69 1 2 2 2 1.482E7 0.00 14.69 2 2 211 23.0 4.42 HVO_1685 conserved hypothetical protein 14.63 1 6 6 15 7.346E7 13.31 12.40 5 7 883.18 14.63 6 8 492 54.5 5.74 HVO_1593 PAC2 family protein 14.52 1 2 2 6 9.710E7 7.94 14.52 2 3 429.00 14.52 2 3 248 26.6 4.46 HVO_0233 ribose-phosphate pyrophosphokinase 14.49 1 3 3 15 1.194E8 13.27 14.49 3 8 994.81 14.49 3 7 283 29.6 4.40 HVO_0741 DNA-directed DNA polymerase X 14.43 1 5 5 10 2.286E7 6.40 14.43 5 5 423.66 14.43 5 5 582 62.6 4.44 HVO_2373 30S ribosomal protein S8e 14.40 1 2 2 8 7.431E7 5.44 14.40 2 4 358.43 14.40 2 4 125 13.6 10.48 HVO_1809 isochorismatase family protein 14.21 1 2 2 6 4.000E7 2.55 14.21 2 3 280.26 14.21 2 3 190 21.0 4.55 HVO_0069 sulfatase 14.17 1 7 7 15 3.173E7 7.96 7.77 4 6 839.05 14.17 7 9 515 57.4 4.35 HVO_1536 phosphoglycolate phosphatase 14.16 1 2 2 4 1.526E7 4.82 14.16 2 2 246.50 14.16 2 2 226 24.1 4.27 HVO_2311 glutamyl-tRNA reductase 14.10 1 4 4 9 1.892E7 8.12 9.76 3 4 658.33 14.10 4 5 461 49.2 4.54 HVO_B0154 receiver/sensor box histidine kinase 14.07 1 14 14 44 6.520E7 28.86 14.07 14 22 2421.88 14.07 14 22 1301 144.1 4.39 HVO_2158 malic enzyme (NADP) 13.85 1 2 6 29 2.274E8 18.42 9.72 5 14 1417.48 13.85 6 15 751 81.4 4.55 HVO_1179 homolog to NAD kinase 13.84 1 3 3 4 6.530E7 292.55 13.84 3 4 354 36.7 4.60 HVO_1861 thiamine-monophosphate kinase 13.80 1 4 4 12 3.871E7 9.75 13.80 4 6 658.68 13.80 4 6 297 30.8 4.32 HVO_A0021 conserved hypothetical protein 13.74 1 2 2 3 5.450E7 388.32 13.74 2 3 131 14.9 4.42 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 13.61 1 4 4 17 7.591E7 17.23 13.61 4 9 1005.35 10.56 3 8 360 39.5 4.31 HVO_A0476 conserved hypothetical protein 13.60 1 4 4 11 4.327E7 5.26 11.18 3 5 633.31 13.60 4 6 331 35.4 4.26 HVO_0866 homolog to alanine-tRNA ligase 13.52 1 2 2 4 2.881E7 5.98 13.52 2 2 390.67 13.52 2 2 244 27.1 4.74 HVO_0989 conserved hypothetical protein 13.49 1 2 2 6 7.647E7 0.00 13.49 2 3 186.32 13.49 2 3 126 14.4 4.81 HVO_2955 DEAD/DEAH box helicase 13.48 1 8 8 15 6.330E7 2.47 11.30 7 7 417.35 11.04 7 8 779 85.8 4.94 HVO_0156 "tRNA (guanine(10),N(2))-dimethyltransferase" 13.40 1 4 4 12 2.715E7 14.44 13.40 4 6 808.23 13.40 4 6 321 34.2 5.25 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 13.38 1 5 5 17 2.876E8 17.95 13.38 5 9 964.36 11.71 4 8 299 32.0 4.53 HVO_1407 HTH domain protein 13.33 1 2 2 7 6.086E7 2.40 13.33 2 3 328.92 13.33 2 4 225 24.9 4.45 HVO_1419 HTH-10 family transcription regulator 13.33 1 3 3 5 2.874E7 0.00 13.33 3 3 57.01 10.22 2 2 225 25.2 4.77 HVO_0797 conserved hypothetical protein 13.29 1 2 2 6 2.882E7 6.26 13.29 2 3 226.00 13.29 2 3 173 17.6 4.44 HVO_1354 DNA mismatch repair protein MutS 13.28 1 8 8 23 9.620E7 16.63 13.28 8 12 1041.75 11.90 7 11 580 62.1 4.56 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 13.28 1 4 4 12 6.994E7 5.30 13.28 4 6 419.60 13.28 4 6 482 50.6 4.31 HVO_2248 conserved hypothetical protein 13.28 1 3 3 8 1.515E7 6.45 13.28 3 4 378.76 13.28 3 4 271 31.3 4.77 HVO_0304 electron transfer flavoprotein alpha subunit 13.25 1 2 2 5 9.114E7 680.46 13.25 2 5 317 33.5 4.18 HVO_0848 endonuclease III 13.22 1 2 2 6 3.689E7 5.12 13.22 2 3 266.53 13.22 2 3 227 25.5 4.55 HVO_A0388 Lrp/AsnC family transcription regulator 13.22 1 2 2 8 4.552E7 3.93 13.22 2 4 358.31 13.22 2 4 174 20.1 4.86 HVO_0732 "ribonuclease H, type 1" 13.20 1 3 3 8 2.870E7 4.60 13.20 3 4 376.78 13.20 3 4 197 21.5 5.07 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 13.16 1 4 4 11 5.868E7 9.53 9.62 3 5 723.63 9.87 3 6 395 42.4 4.54 HVO_1323 "shikimate kinase, archaeal-type" 13.15 1 3 3 14 2.681E8 11.77 13.15 3 7 1128.23 13.15 3 7 289 29.5 4.30 HVO_1936 F420-0:gamma-glutamyl ligase 13.15 1 3 3 8 5.049E7 4.77 13.15 3 4 452.12 13.15 3 4 251 27.4 4.68 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 13.15 1 4 4 22 1.353E8 21.45 13.15 4 11 1104.61 13.15 4 11 403 41.1 4.73 HVO_B0057 precorrin-3B C17-methyltransferase 13.08 1 3 3 12 1.615E8 14.83 13.08 3 6 939.24 13.08 3 6 344 36.3 4.31 HVO_2529 probable oxidoreductase (short-chain dehydrogenase family) 13.04 1 2 2 6 5.492E7 5.09 13.04 2 3 312.80 13.04 2 3 230 23.6 4.72 HVO_0781 S-adenosylmethionine hydroxide adenosyltransferase family protein 12.98 1 2 2 2 2.287E6 138.59 12.98 2 2 262 27.7 4.79 HVO_1648 adenylate cyclase 12.97 1 2 2 6 2.074E7 2.54 12.97 2 3 281.58 12.97 2 3 185 20.5 4.34 HVO_1077 diphthamide biosynthesis protein Dph6 12.92 1 2 2 6 5.042E7 4.08 12.92 2 3 337.77 12.92 2 3 240 26.0 4.15 HVO_B0066 Lrp/AsnC family transcription regulator 12.80 1 2 2 6 3.875E7 8.60 12.80 2 3 385.02 12.80 2 3 164 18.5 4.41 HVO_0824 "probable glycosyltransferase, type 1" 12.78 1 3 3 12 2.615E7 5.76 12.78 3 6 610.82 12.78 3 6 352 39.6 5.08 HVO_1995 conserved hypothetical protein 12.76 1 3 3 14 3.447E7 14.34 12.76 3 7 826.15 12.76 3 7 243 26.5 4.39 HVO_A0150 TrmB family transcription regulator 12.71 1 5 5 15 1.519E8 10.23 12.71 5 7 833.76 12.71 5 8 354 39.0 4.63 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 12.66 1 4 4 11 4.214E7 7.48 12.66 4 6 586.78 8.18 3 5 379 41.7 4.83 HVO_0675 pantoate kinase 12.64 1 3 3 6 5.182E7 3.59 9.39 2 3 284.16 7.22 2 3 277 27.8 4.54 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 12.56 1 4 4 12 1.310E8 12.60 12.56 4 6 722.45 12.56 4 6 398 43.4 4.37 HVO_2004 serine O-acetyltransferase 12.54 1 2 3 14 4.508E8 8.87 12.54 3 7 586.41 12.54 3 7 287 31.9 5.21 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 12.53 1 5 5 15 7.271E7 8.49 10.25 4 7 858.49 12.53 5 8 439 47.2 4.59 HVO_1446 "fructose-1,6-bisphosphatase" 12.46 1 2 2 4 2.134E7 595.66 12.46 2 4 297 31.6 4.45 HVO_0757 probable oxidoreductase (aldo-keto reductase family protein) 12.40 1 3 3 6 2.492E7 0.00 12.40 3 3 143.62 12.40 3 3 363 39.1 4.77 HVO_A0524 3-hydroxyacyl-CoA dehydrogenase 12.24 1 2 2 2 1.463E7 100.07 12.24 2 2 294 31.3 4.45 HVO_C0054 hypothetical protein 12.21 1 3 3 10 3.826E7 5.21 12.21 3 5 368.54 12.21 3 5 344 37.5 4.70 HVO_A0550 receiver/sensor box histidine kinase 12.09 1 9 10 23 3.313E7 16.96 11.30 9 12 1297.39 10.96 9 11 885 95.9 4.46 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 12.05 1 8 8 38 9.946E7 21.04 12.05 8 20 1611.22 12.05 8 18 838 89.1 4.65 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 12.04 1 0 6 15 1.160E8 12.69 12.04 6 8 649.75 10.19 5 7 432 48.1 5.02 HVO_0568 TrmB family transcription regulator 12.03 1 4 4 11 1.616E7 8.13 8.31 3 5 567.87 12.03 4 6 349 38.3 4.56 HVO_A0485 aminotransferase class V 11.97 1 3 3 10 9.414E7 12.33 11.97 3 5 852.55 11.97 3 5 351 37.3 4.26 HVO_A0439 DUF2800 family protein 11.96 1 1 3 3 4.082E7 127.15 11.96 3 3 326 36.9 4.51 HVO_1723 DNA repair helicase Rad25 11.94 1 8 8 26 5.430E7 17.06 11.94 8 13 1432.07 9.93 7 13 695 76.8 4.69 HVO_0837 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 11.93 1 2 2 8 2.601E7 9.78 11.93 2 4 575.69 11.93 2 4 243 24.8 4.48 HVO_2160 conserved hypothetical protein 11.92 1 16 16 131 1.409E9 171.77 11.92 16 64 11881.86 11.92 16 67 2257 232.7 3.92 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 11.86 1 4 4 9 8.507E7 1.90 11.86 4 4 312.84 11.86 4 5 388 41.9 4.35 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 11.85 1 3 3 29 2.391E8 25.26 11.85 3 14 1934.46 11.85 3 15 363 39.7 4.25 HVO_C0043 conserved hypothetical protein 11.80 1 5 5 9 2.818E7 3.00 9.68 4 4 212.42 11.80 5 5 661 73.8 4.75 HVO_2891 thymidine kinase 11.79 1 2 2 10 3.253E7 9.32 11.79 2 5 628.44 11.79 2 5 195 21.4 4.63 HVO_1344 SBDS family protein 11.76 1 2 2 7 3.836E7 7.43 11.76 2 4 426.40 11.76 2 3 238 26.5 4.51 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 6 3.072E8 2.25 11.64 2 2 273.57 11.64 2 4 189 20.3 4.22 HVO_2250 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 11.60 1 2 2 8 8.823E7 1.64 11.60 2 4 212.38 11.60 2 4 181 19.5 4.28 HVO_2350 YyaL family protein 11.59 1 4 4 16 7.882E7 6.66 11.59 4 8 730.78 11.59 4 8 552 58.8 4.59 HVO_2858 Lrp/AsnC family transcription regulator 11.54 1 2 2 4 1.423E7 1.96 11.54 2 2 149.22 11.54 2 2 156 17.6 4.61 HVO_1150 IS200-type transposase 11.54 1 2 2 4 3.488E7 327.45 11.54 2 4 130 14.7 5.49 HVO_2056 "probable epimerase (homolog to dTDP-4-dehydrorhamnose 3,5-epimerase)" 11.54 1 2 2 3 1.915E7 353.60 11.54 2 3 156 18.3 4.55 HVO_A0257 Orc1-type DNA replication protein 11.53 1 4 4 13 2.895E7 13.56 11.53 4 7 780.99 7.53 3 6 425 48.0 4.94 HVO_1710 alpha amylase 11.52 1 8 8 24 9.320E7 13.51 11.52 8 12 1393.46 11.52 8 12 677 75.0 4.45 HVO_2510 GNAT family acetyltransferase 11.51 1 3 3 8 3.382E7 4.01 11.51 3 4 527.85 11.51 3 4 304 33.7 4.49 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 11.46 1 5 5 14 2.449E7 7.86 11.46 5 7 541.01 11.46 5 7 410 46.0 4.89 HVO_1565 DNA ligase (ATP) 11.45 1 6 6 22 2.666E7 19.18 11.45 6 11 1242.78 11.45 6 11 585 62.7 4.44 HVO_2545 50S ribosomal protein L18 11.41 1 2 2 4 4.967E7 1.87 11.41 2 2 173.26 11.41 2 2 184 20.2 5.60 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 11.40 1 5 5 32 3.284E8 24.34 11.40 5 16 1821.48 11.40 5 16 430 44.2 4.37 HVO_0431 HAD superfamily hydrolase 11.27 1 3 3 10 4.697E7 6.33 11.27 3 5 500.86 11.27 3 5 284 30.4 4.26 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 11.23 1 0 6 18 1.107E8 16.97 11.23 6 9 931.61 11.23 6 9 472 51.6 5.16 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 11.22 1 7 7 19 6.768E7 15.14 11.22 7 9 1023.28 11.22 7 10 740 85.6 4.70 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 11.20 1 0 5 24 1.334E8 20.46 11.20 5 12 1606.40 11.20 5 12 384 42.4 5.40 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 11.20 1 2 2 6 3.500E7 4.92 11.20 2 3 408.19 11.20 2 3 241 26.1 4.58 HVO_1681 DNA N-glycosylase 11.18 1 3 3 8 3.537E7 8.64 11.18 3 4 570.13 11.18 3 4 304 34.2 4.63 HVO_B0277 HTH domain protein 11.07 1 2 2 6 3.910E7 2.15 11.07 2 3 141.02 11.07 2 3 262 29.5 4.50 HVO_1038 uracil-DNA glycosylase superfamily protein 11.06 1 2 2 4 6.035E7 4.16 11.06 2 2 173.02 11.06 2 2 208 22.7 4.61 HVO_1340 "probable glycosyltransferase, type 1" 10.93 1 4 4 11 1.305E8 7.98 10.93 4 6 585.94 9.07 3 5 375 41.0 4.42 HVO_1374 acyl-CoA synthetase 10.85 1 5 5 18 6.918E7 12.23 10.85 5 9 1073.06 10.85 5 9 553 61.1 4.50 HVO_1470 isochorismate synthase 10.84 1 3 3 12 1.107E8 6.88 10.84 3 6 642.08 10.84 3 6 443 47.7 4.56 HVO_2131 "fructose-1,6-bisphosphatase" 10.73 1 2 2 8 2.179E7 12.09 10.73 2 4 604.56 10.73 2 4 289 31.3 4.48 21961227 Keratin 6B [Homo sapiens] 10.64 1 0 7 36 1.795E8 32.72 10.64 7 18 2432.54 10.64 7 18 564 60.0 8.00 HVO_1650 polyphosphate kinase 10.58 1 6 6 14 2.478E7 8.10 7.21 5 7 617.91 8.65 5 7 832 93.6 4.65 HVO_A0119 cyclase family protein 10.57 1 0 2 4 1.343E8 0.00 10.57 2 2 113.07 10.57 2 2 227 25.5 4.59 HVO_A0415 cyclase family protein 10.57 1 0 2 4 1.343E8 0.00 10.57 2 2 113.07 10.57 2 2 227 25.5 4.59 HVO_0014 ATP-dependent DNA helicase Hel308a 10.52 1 7 7 20 5.527E7 11.33 10.52 7 10 1021.98 10.52 7 10 827 90.3 4.67 HVO_1387 enoyl-CoA hydratase 10.51 1 2 2 2 1.923E7 104.27 10.51 2 2 257 27.5 4.51 HVO_1537 Orc1-type DNA replication protein 10.50 1 3 3 9 2.942E7 3.98 10.50 3 4 252.57 10.50 3 5 400 42.4 5.52 HVO_A0158 acyl-CoA synthetase 10.46 1 1 4 10 4.059E7 2.43 10.46 4 5 356.39 8.92 3 5 650 71.2 4.63 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 10.36 1 3 3 12 4.185E7 10.61 10.36 3 6 629.39 10.36 3 6 386 41.3 4.46 HVO_1228 halocyanin 10.35 1 8 8 30 8.634E7 28.36 10.35 8 15 2002.88 10.35 8 15 821 83.7 4.17 HVO_A0583 IclR family transcription regulator 10.16 1 3 3 6 1.904E7 1.98 10.16 3 3 217.11 10.16 3 3 256 27.9 5.07 HVO_C0050 conserved hypothetical protein 10.15 1 2 2 7 1.678E7 0.00 10.15 2 3 231.18 10.15 2 4 266 30.7 4.59 HVO_0322 MinD/ParA domain protein 10.15 1 3 3 17 2.086E8 21.43 10.15 3 8 1202.91 10.15 3 9 581 58.8 3.70 HVO_A0156 acyl-CoA synthetase 10.09 1 0 6 16 1.134E8 8.32 10.09 6 8 704.15 8.58 5 8 664 74.0 4.40 HVO_0148 urease alpha subunit 10.04 1 3 3 3 3.763E7 0.00 10.04 3 3 568 60.3 4.54 HVO_0135 RIO-type serine/threonine protein kinase 10.00 1 3 3 14 3.687E7 9.28 10.00 3 7 820.50 10.00 3 7 290 33.0 4.81 HVO_2914 conserved hypothetical protein 10.00 1 2 2 2 2.175E7 68.60 10.00 2 2 140 16.1 4.61 4557890 keratin 5 [Homo sapiens] 9.83 1 0 7 31 1.434E8 24.78 8.31 6 15 1962.16 9.83 7 16 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 9.83 1 0 7 31 1.434E8 24.78 8.31 6 15 1962.16 9.83 7 16 590 62.4 8.06 HVO_0689 chromosome segregation protein Smc 9.68 1 9 9 25 6.545E7 13.95 9.68 9 13 1017.40 9.03 8 12 1240 138.1 4.39 HVO_2736 tRNA(Met) cytidine acetyltransferase 9.68 1 6 6 18 3.144E7 3.52 9.68 6 9 573.76 9.68 6 9 754 81.2 4.96 HVO_0476 conserved hypothetical protein 9.63 1 2 2 8 1.756E7 5.57 9.63 2 4 471.18 9.63 2 4 218 23.8 4.60 HVO_1864 molybdopterin synthase catalytic subunit 9.58 1 3 3 10 6.780E7 6.28 9.58 3 5 411.71 9.58 3 5 261 27.9 4.41 HVO_B0200 malate synthase 9.40 1 2 2 8 2.410E8 5.22 9.40 2 4 679.24 9.40 2 4 436 48.3 4.30 HVO_2573 probable methenyltetrahydrofolate cyclohydrolase 9.35 1 2 2 8 6.300E7 11.75 9.35 2 4 882.89 9.35 2 4 310 32.7 3.92 HVO_2697 DNA primase small subunit 9.35 1 3 3 10 1.952E7 6.77 9.35 3 5 439.51 9.35 3 5 385 42.6 4.72 HVO_A0093 IclR family transcription regulator 9.35 1 3 3 10 1.484E7 0.00 9.35 3 5 361.79 9.35 3 5 246 27.5 5.15 HVO_2932 GTP-binding protein 9.34 1 3 3 11 6.056E7 2.22 9.34 3 6 436.63 9.34 3 5 396 43.5 4.51 HVO_C0067 FAD-dependent oxidoreductase 9.34 1 3 3 16 8.849E7 18.91 9.34 3 8 974.76 9.34 3 8 396 42.7 4.30 HVO_A0401 Fido domain protein 9.33 1 2 2 6 9.352E6 4.85 9.33 2 3 310.51 9.33 2 3 386 43.5 4.72 HVO_A0551 acyl-CoA synthetase 9.29 1 4 4 14 2.780E7 19.96 9.29 4 7 956.86 9.29 4 7 538 59.6 4.65 HVO_1357 receiver/bat box HTH-10 family transcription regulator 9.28 1 4 4 8 4.063E7 8.09 9.28 4 5 350.18 8.25 3 3 582 62.7 4.40 HVO_0558 SAMP-activating enzyme E1 9.26 1 2 2 8 6.821E7 4.15 9.26 2 4 553.22 9.26 2 4 270 28.7 4.35 HVO_0507 creatininase 9.17 1 2 2 6 3.354E7 0.00 9.17 2 3 196.22 9.17 2 3 240 25.6 4.56 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 9.15 1 4 4 7 3.152E7 0.00 9.15 4 4 316.62 7.72 3 3 492 52.1 4.83 HVO_1373 acyl-CoA dehydrogenase 9.14 1 2 2 2 3.388E8 2.33 9.14 2 2 383 42.5 4.61 HVO_0572 lipoate-protein ligase 9.09 1 2 2 6 3.051E7 5.83 9.09 2 3 384.70 9.09 2 3 275 30.5 4.84 HVO_A0562 urocanate hydratase 9.03 1 4 4 9 2.169E7 9.18 9.03 4 5 414.75 6.94 3 4 620 67.9 4.70 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 9.00 1 3 3 10 3.392E7 6.10 9.00 3 5 673.75 9.00 3 5 400 44.2 4.32 HVO_2880 probable peptide chain release factor pelota 8.99 1 3 3 8 1.108E8 5.10 8.99 3 4 499.10 8.99 3 4 356 39.3 4.63 HVO_2503 kynureninase 8.94 1 2 3 7 4.936E7 0.00 7.29 2 3 243.47 8.94 3 4 425 46.0 4.54 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 8.87 1 0 6 28 1.434E8 22.17 8.87 6 14 1775.07 8.87 6 14 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 8.87 1 0 6 28 1.434E8 22.17 8.87 6 14 1775.07 8.87 6 14 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 8.87 1 0 6 28 1.434E8 22.17 8.87 6 14 1775.07 8.87 6 14 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 8.87 1 0 6 28 1.434E8 22.17 8.87 6 14 1775.07 8.87 6 14 564 60.0 7.72 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 8.78 1 3 4 11 4.102E7 8.17 8.78 4 5 624.40 8.78 4 6 444 47.1 4.77 HVO_0680 (S)-3-O-geranylgeranylglyceryl phosphate synthase 1 8.75 1 2 2 3 1.217E8 326.24 8.75 2 3 240 26.5 4.17 HVO_1309 peptidase M24 family protein 8.70 1 4 4 20 1.235E8 18.42 8.70 4 10 1026.73 8.70 4 10 391 42.1 4.36 HVO_0305 electron transfer flavoprotein beta subunit 8.68 1 2 2 4 6.578E7 3.79 8.68 2 4 265 28.5 4.04 HVO_B0149 oleate hydratase 8.63 1 3 4 7 1.854E8 2.04 8.63 4 4 181.56 5.07 3 3 533 60.1 4.64 HVO_0522 HdaI-type histone deacetylase 8.61 1 3 3 7 4.579E6 3.91 8.61 3 4 368.78 5.93 2 3 337 36.3 4.45 HVO_1812 conserved hypothetical protein 8.53 1 3 3 10 5.377E7 7.99 8.53 3 5 644.75 8.53 3 5 375 40.5 4.50 HVO_1914 acetyl-CoA C-acyltransferase 8.49 1 2 2 4 5.353E7 0.00 8.49 2 2 180.83 8.49 2 2 377 39.9 4.41 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 8.39 1 2 2 5 2.432E7 0.00 8.39 2 3 120.04 8.39 2 2 286 30.8 4.46 HVO_A0003 ParA domain protein 8.39 1 2 2 8 1.007E7 7.52 8.39 2 4 476.10 8.39 2 4 274 30.3 4.53 HVO_1746 DUF2800 family protein 8.36 1 1 2 4 5.524E7 5.66 8.36 2 2 204.43 8.36 2 2 323 36.5 4.37 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 8.25 1 0 4 11 1.160E8 10.34 8.25 4 6 512.14 6.25 3 5 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 8.25 1 0 4 11 1.160E8 10.34 8.25 4 6 512.14 6.25 3 5 400 44.1 5.14 HVO_1457 conserved hypothetical protein 8.25 1 2 2 4 2.274E7 0.00 8.25 2 2 124.15 8.25 2 2 291 32.8 4.40 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 8.24 1 3 3 10 4.382E7 5.63 8.24 3 5 499.40 8.24 3 5 437 47.1 4.72 HVO_B0101 IclR family transcription regulator 8.17 1 2 2 4 1.869E7 2.70 8.17 2 2 289.22 8.17 2 2 257 28.6 5.02 HVO_0968 NADH dehydrogenase-like complex subunit CD 8.16 1 0 5 22 3.298E8 24.80 8.16 5 11 1533.23 8.16 5 11 564 63.3 4.60 HVO_2640 conserved hypothetical protein 8.09 1 3 3 5 2.353E7 2.70 8.09 3 3 203.08 6.15 2 2 309 33.9 4.56 HVO_1704 homolog to arabinopyranose mutase 8.05 1 3 3 9 4.089E7 8.73 5.97 2 4 844.15 8.05 3 5 385 43.4 4.23 HVO_2923 proteasome alpha subunit 8.03 1 1 2 6 3.437E8 6.85 8.03 2 3 376.36 8.03 2 3 249 26.7 4.39 HVO_0236 tRNA (guanine(26)-N(2))-dimethyltransferase 7.98 1 2 2 3 2.414E7 198.32 7.98 2 3 376 40.9 4.97 HVO_1425 conserved hypothetical protein 7.92 1 2 2 6 5.436E7 0.00 7.92 2 3 288.42 7.92 2 3 265 30.4 4.61 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 7.84 1 2 2 8 2.702E8 5.63 7.84 2 4 334.19 7.84 2 4 574 62.8 4.17 HVO_2905 MaoC family protein 7.84 1 1 2 3 9.933E7 204.23 7.84 2 3 153 17.2 4.32 HVO_2321 bacterial-type DNA primase DnaG 7.63 1 3 3 6 3.885E7 4.57 7.63 3 3 257.94 7.63 3 3 472 49.4 4.36 HVO_B0233 alpha-L-arabinofuranosidase 7.63 1 3 3 6 2.806E7 6.32 7.63 3 3 372.78 7.63 3 3 511 57.5 4.39 HVO_1083 glucose 1-dehydrogenase 7.56 1 2 2 3 3.779E7 273.55 7.56 2 3 357 39.0 4.73 HVO_1380 methylmalonyl-CoA mutase subunit A 7.53 1 3 3 10 4.071E7 9.20 7.53 3 5 550.03 7.53 3 5 558 61.9 4.41 HVO_2628 GHMP family kinase (homolog to beta-ribofuranosylaminobenzene 5'-phosphate synthase) 7.50 1 2 2 4 2.174E7 2.67 7.50 2 2 260.10 7.50 2 2 320 33.5 5.27 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 7.42 1 3 3 8 5.558E7 8.62 7.42 3 4 450.52 7.42 3 4 337 35.9 4.39 HVO_A0559 histidine ammonia-lyase 7.39 1 3 3 6 2.415E7 4.71 7.39 3 3 219.07 7.39 3 3 528 55.5 4.84 HVO_A0254 DUF234 domain protein 7.38 1 4 4 12 3.673E7 6.27 5.86 3 6 512.96 7.38 4 6 461 52.7 4.78 HVO_1564 conserved hypothetical protein 7.27 1 3 3 7 2.811E7 9.05 7.27 3 4 309.04 4.72 2 3 509 56.5 4.65 HVO_0687 M20 family amidohydrolase 7.21 1 3 3 10 2.412E7 4.88 7.21 3 5 630.69 7.21 3 5 444 47.5 4.58 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 7.19 1 0 4 14 1.107E8 14.61 7.19 4 7 794.00 7.19 4 7 473 51.2 5.05 HVO_0077 uroporphyrin-III C-methyltransferase 7.17 1 2 2 5 1.901E7 1.82 7.17 2 2 166.65 7.17 2 3 293 30.5 4.50 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 7.12 1 2 2 4 2.703E7 3.95 7.12 2 2 271.58 7.12 2 2 323 34.9 5.24 HVO_2263 conserved hypothetical protein 7.12 1 4 4 8 1.007E8 4.09 5.99 3 4 334.13 4.99 3 4 801 89.5 5.54 HVO_1047 NADPH:quinone reductase 7.12 1 2 2 3 3.133E7 349.09 7.12 2 3 323 33.8 4.27 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 7.11 1 4 4 10 4.129E7 5.76 3.26 3 4 476.53 7.11 4 6 858 93.9 4.69 386849 keratin type II 7.10 1 0 4 12 9.045E7 12.69 7.10 4 6 820.81 7.10 4 6 563 59.9 7.94 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 6 1.086E8 7.60 7.07 2 3 508.07 7.07 2 3 297 32.3 3.98 HVO_A0560 imidazolonepropionase 7.04 1 2 2 4 1.293E7 0.00 7.04 2 2 123.36 7.04 2 2 412 42.4 4.46 HVO_0029 UvrABC system protein B 7.02 1 4 4 12 3.331E7 8.47 7.02 4 6 617.25 7.02 4 6 698 79.0 4.45 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 8 5.741E8 2.49 6.94 3 4 525.02 6.94 3 4 389 40.8 4.89 HVO_2860 conserved hypothetical protein 6.94 1 3 3 8 1.874E7 0.00 6.94 3 4 327.37 6.94 3 4 562 58.9 4.49 HVO_B0025 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 6.94 1 2 2 3 3.636E7 135.68 6.94 2 3 346 37.2 4.53 HVO_1735 conserved hypothetical protein 6.82 1 4 4 14 1.955E7 5.57 6.82 4 7 573.06 6.82 4 7 660 75.7 4.50 HVO_A0064 Orc1-type DNA replication protein 6.81 1 1 2 4 3.297E7 0.00 6.81 2 2 55.12 6.81 2 2 499 55.5 4.91 HVO_B0052 PQQ repeat protein 6.80 1 3 3 8 4.478E7 6.18 6.80 3 4 454.54 6.80 3 4 412 44.1 5.48 HVO_2605 MiaB-like tRNA modifying enzyme 6.76 1 2 2 10 5.885E7 1.94 6.76 2 5 415.16 6.76 2 5 429 47.4 5.03 31074631 keratin 1b [Homo sapiens] 6.75 1 1 4 17 2.313E8 14.05 6.75 4 9 990.29 4.67 3 8 578 61.8 5.97 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 6.69 1 2 2 4 2.436E7 0.00 6.69 2 2 116.46 6.69 2 2 359 39.4 4.91 HVO_0815 arNOG05395 family transcription regulator 6.56 1 2 2 6 1.580E7 1.97 6.56 2 3 186.52 6.56 2 3 259 26.9 4.42 HVO_1008 GFO family oxidoreductase 6.33 1 2 2 6 2.752E7 4.15 6.33 2 3 319.92 6.33 2 3 332 36.0 4.72 HVO_2381 UPF0272 family protein 6.29 1 2 2 6 3.014E7 8.45 6.29 2 3 593.05 6.29 2 3 493 52.3 4.88 HVO_1668 gamma-glutamylcysteine synthetase 6.15 1 2 2 6 1.363E7 1.81 6.15 2 3 271.15 6.15 2 3 358 39.9 4.72 HVO_2809 succinate dehydrogenase subunit B (iron-sulfur protein) 6.14 1 2 2 8 2.826E7 2.26 6.14 2 4 323.54 6.14 2 4 293 33.9 5.27 HVO_0745 "FtsZ family protein, type III" 6.11 1 2 2 4 2.136E7 1.89 6.11 2 2 183.22 6.11 2 2 360 37.1 4.51 HVO_2479 2-phospho-L-lactate transferase 6.06 1 2 2 4 1.204E7 4.40 6.06 2 2 257.07 6.06 2 2 330 34.7 4.32 HVO_1676 transcription initiation factor TFB 6.02 1 0 2 8 1.747E8 7.66 6.02 2 4 466.93 6.02 2 4 332 37.3 5.49 HVO_0662 HTH domain protein / thiamine-phosphate synthase 6.02 1 2 2 3 2.562E7 392.42 6.02 2 3 299 31.9 4.44 HVO_2058 NAD-dependent epimerase/dehydratase (homolog to dTDP-4-dehydrorhamnose reductase) 6.00 1 2 2 8 1.941E8 5.99 6.00 2 4 456.18 6.00 2 4 300 32.0 4.22 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 5.95 1 2 2 7 9.897E7 6.03 5.95 2 4 314.04 5.95 2 3 353 36.7 4.65 HVO_2187 CHP01210 family protein 5.83 1 2 2 4 1.691E7 2.56 5.83 2 2 182.30 5.83 2 2 360 40.0 4.58 HVO_2871 pyridoxal phosphate-dependent aminotransferase 5.56 1 2 3 8 1.043E7 6.56 5.56 3 4 341.43 5.56 3 4 450 49.1 4.70 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 5.51 1 2 2 6 1.257E9 2.58 5.51 2 3 283.18 5.51 2 3 345 37.0 3.95 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 5.48 1 0 3 10 1.042E8 10.34 5.48 3 5 512.14 5.48 3 5 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 5.48 1 0 3 10 1.042E8 10.34 5.48 3 5 512.14 5.48 3 5 456 49.2 4.77 HVO_1169 "probable glycosyltransferase, type 1" 5.43 1 2 2 4 1.026E7 3.49 5.43 2 2 166.60 5.43 2 2 368 40.8 4.73 HVO_1052 transcription initiation factor TFB 5.42 1 0 2 8 1.719E8 7.50 5.42 2 4 486.45 5.42 2 4 332 37.3 5.25 HVO_2598 polyphosphate kinase 5.35 1 3 3 4 9.619E7 1.74 3.08 2 2 99.83 3.88 2 2 747 83.6 5.11 HVO_0311 A-type ATP synthase subunit I 5.32 1 3 4 11 5.171E7 9.40 5.32 4 6 551.12 4.50 3 5 733 79.5 4.41 HVO_2071 conserved hypothetical protein 5.28 1 3 3 8 6.465E7 7.94 5.28 3 4 490.41 5.28 3 4 549 58.4 4.72 HVO_2683 5'-nucleotidase family hydrolase 5.23 1 2 2 2 2.180E7 151.54 5.23 2 2 459 48.5 4.60 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 5.06 1 3 3 6 6.715E7 4.18 5.06 3 3 237.04 5.06 3 3 573 62.9 4.45 HVO_0477 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 5.02 1 2 2 3 1.074E8 384.29 5.02 2 3 319 33.4 4.18 HVO_0283 archaea-specific helicase AshA 4.97 1 2 3 3 5.060E7 157.24 4.97 3 3 684 76.3 5.53 HVO_1651 thiamine / thiouridine biosynthesis protein ThiI 4.86 1 2 2 4 5.111E6 4.60 4.86 2 2 264.98 4.86 2 2 391 41.7 4.82 4504911 keratin 13 isoform b [Homo sapiens] 4.76 1 0 2 6 4.899E7 7.26 4.76 2 3 344.04 4.76 2 3 420 45.8 4.88 HVO_B0038A D-xylonate dehydratase 4.61 1 0 2 16 4.992E8 12.09 4.61 2 8 864.14 4.61 2 8 412 45.5 4.55 HVO_A0346 XerC/D-like integrase 4.58 1 2 2 6 9.508E6 6.22 4.58 2 3 255.97 4.58 2 3 415 46.8 4.78 HVO_A0267 D-galactonate dehydratase 4.44 1 2 2 4 4.357E6 4.15 4.44 2 2 226.51 4.44 2 2 383 42.5 4.86 HVO_1916 Kef-type transport system (probable substrate potassium) 4.41 1 3 3 6 5.179E7 4.31 4.41 3 3 345.61 4.41 3 3 635 66.2 4.63 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 4.37 1 0 2 6 4.899E7 7.26 4.37 2 3 344.04 4.37 2 3 458 49.6 4.96 HVO_A0001 Orc1-type DNA replication protein 4.33 1 1 2 2 4.148E7 2.40 4.33 2 2 416 47.0 4.97 HVO_0073 single-stranded-DNA-specific exonuclease RecJ1 4.20 1 2 2 8 2.058E7 4.33 4.20 2 4 338.74 4.20 2 4 476 50.6 4.68 HVO_C0074 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 4.06 1 2 2 4 1.875E7 4.59 4.06 2 2 245.32 4.06 2 2 690 75.9 4.79 HVO_2042 Orc1-type DNA replication protein 3.91 1 2 2 3 8.271E6 274.20 3.91 2 3 409 45.6 5.30 HVO_0418 homolog to haloviral protein 3.82 1 2 2 4 6.521E6 0.00 3.82 2 2 114.28 3.82 2 2 498 57.6 5.22 31074633 keratin 6L [Homo sapiens] 3.55 1 0 2 8 1.096E8 7.87 3.55 2 4 589.47 3.55 2 4 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 3.55 1 0 2 8 1.096E8 7.87 3.55 2 4 589.47 3.55 2 4 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 3.55 1 0 2 8 1.096E8 7.87 3.55 2 4 589.47 3.55 2 4 535 57.7 7.20 4504919 keratin 8 [Homo sapiens] 3.52 1 0 3 20 1.138E8 11.20 3.52 3 10 1122.92 3.52 3 10 483 53.7 5.59 HVO_0990 DHH family phosphoesterase 3.50 1 1 2 2 1.907E7 69.17 3.50 2 2 486 51.9 4.59 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 8 1.507E8 7.93 3.45 2 4 453.77 3.45 2 4 464 50.6 5.47 HVO_1940 DNA mismatch repair protein MutS 3.15 1 3 3 6 1.715E7 1.90 3.15 3 3 183.27 3.15 3 3 921 99.4 4.42 HVO_2183 aldehyde ferredoxin oxidoreductase 3.11 1 2 2 4 5.119E6 360.39 3.11 2 4 643 69.3 4.59 HVO_0065 DNA-directed DNA polymerase D large subunit 2.91 1 2 2 8 2.815E7 2.36 2.91 2 4 153.86 2.91 2 4 1202 133.9 4.60 109255249 keratin 4 [Homo sapiens] 2.69 1 0 2 6 6.700E7 4.57 2.69 2 3 338.39 2.69 2 3 594 63.9 8.25 46397807 "Keratin, type I cuticular Ha7 (Hair keratin, type I Ha7)" 2.67 1 0 2 3 1.283E8 224.27 2.67 2 3 449 49.7 4.96 18266794 "Keratin, type I cuticular Ha8 (Hair keratin, type I Ha8)" 2.63 1 0 2 3 1.283E8 224.27 2.63 2 3 456 50.5 4.84 15431318 type I hair keratin 8 [Homo sapiens] 2.63 1 0 2 3 1.283E8 224.27 2.63 2 3 456 50.4 4.84 66774007 "Keratin, type II cytoskeletal 1b" 2.60 1 0 2 12 6.531E7 6.02 2.60 2 6 556.10 2.60 2 6 576 61.7 5.85 HVO_0301 receiver/sensor box histidine kinase 1.91 1 0 2 3 1.552E7 279.84 1.91 2 3 629 68.9 4.64 HVO_B0173 SMC-like protein Sph4 1.66 1 1 2 2 1.826E5 112.68 1.66 2 2 662 74.4 4.49