Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0356 translation elongation factor aEF-2 80.61 1 47 47 943 2.422E10 850.45 80.61 47 470 55088.87 80.61 47 473 727 80.4 4.73 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 78.87 1 17 17 196 8.597E9 205.79 78.87 17 98 14170.88 78.87 17 98 355 38.2 4.68 HVO_0359 translation elongation factor aEF-1 alpha subunit 78.62 1 21 24 1163 6.003E10 1099.07 73.16 22 538 85848.74 78.62 24 625 421 45.7 4.73 HVO_1454 aspartate carbamoyltransferase catalytic subunit 73.36 1 13 13 57 4.190E8 48.39 73.36 13 28 3266.01 73.36 13 29 304 33.7 4.92 HVO_0329 branched-chain amino acid aminotransferase 72.44 1 21 21 132 3.384E9 137.13 72.44 21 66 8454.74 68.59 19 66 312 35.0 4.58 HVO_0880 conserved hypothetical protein 71.99 1 25 25 249 4.351E9 260.38 71.99 25 125 17667.97 71.99 24 124 307 36.3 4.74 HVO_0055 CBS domain protein 70.42 1 14 14 70 2.493E9 65.26 67.25 13 34 4806.39 70.42 14 36 284 30.8 4.27 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 70.29 1 17 17 187 6.608E9 192.83 70.29 17 93 13357.29 70.29 17 94 350 37.6 4.54 HVO_1921 serine--tRNA ligase 69.78 1 26 26 138 2.132E9 141.07 69.78 26 70 9751.39 69.78 26 68 460 52.0 4.46 HVO_0581 "cell division protein FtsZ, type II" 67.50 1 17 17 107 2.359E9 113.54 67.50 17 53 8012.44 64.50 16 54 400 42.5 4.75 HVO_0046 putative glutamate--argW ligase 67.35 1 11 11 57 1.073E9 50.69 67.35 11 30 3522.28 45.36 9 27 291 31.9 4.87 HVO_2862 serine hydroxymethyltransferase 66.99 1 16 17 236 8.786E9 181.05 66.99 16 120 13829.08 66.99 17 116 415 44.3 4.53 HVO_0175 DNA polymerase sliding clamp 64.78 1 10 10 129 6.168E9 98.43 64.78 10 65 7210.86 64.78 10 64 247 26.7 4.39 HVO_2900 fumarate hydratase 64.18 1 17 17 183 6.815E9 200.40 62.26 16 93 12896.52 64.18 17 90 469 50.1 4.78 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 64.16 1 16 16 114 5.065E9 98.66 64.16 16 57 7660.83 64.16 16 57 413 45.8 4.45 HVO_0161 ATP phosphoribosyltransferase 64.06 1 12 12 57 1.130E9 46.46 60.14 11 28 3507.08 64.06 12 29 281 30.4 4.60 HVO_0602 3-dehydroquinate dehydratase 63.56 1 12 12 52 4.362E8 43.93 63.56 12 26 3078.13 63.56 12 26 247 27.3 4.51 HVO_0850 proteasome-activating nucleotidase 63.46 1 17 19 105 1.961E9 94.60 56.54 17 50 6685.53 63.46 19 55 405 45.6 4.60 HVO_0133 thermosome subunit 1 63.21 1 21 23 153 4.337E9 140.43 54.29 21 77 10224.38 58.75 22 76 560 58.9 4.25 HVO_2413 translation elongation factor aEF-1 alpha subunit 63.10 1 16 19 140 1.419E10 124.70 51.90 16 65 9601.84 63.10 19 75 420 45.6 4.75 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 61.34 1 6 6 39 1.698E9 23.93 50.52 5 17 2464.33 61.34 6 22 194 20.7 4.12 HVO_1273 inosine-5'-monophosphate dehydrogenase 61.24 1 20 20 208 4.743E9 194.41 58.63 19 105 13427.68 61.24 20 103 498 53.3 4.55 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 60.93 1 15 15 77 1.427E9 80.43 60.93 15 38 5957.72 60.93 15 39 343 38.4 4.94 HVO_0239 glutamine synthetase 60.53 1 18 18 133 5.962E9 134.31 51.97 16 65 8886.61 60.53 18 68 456 50.5 4.56 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 60.50 1 12 12 67 1.932E9 69.88 60.50 12 33 4935.25 60.50 12 34 281 30.6 4.59 HVO_2519 conserved hypothetical protein 60.21 1 14 14 73 1.486E9 79.12 55.50 13 35 5955.50 60.21 14 38 382 40.7 4.35 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 58.45 1 23 23 153 4.962E9 148.68 58.45 23 77 9656.50 58.45 23 76 592 66.6 4.61 HVO_0433 F420H2:NADP oxidoreductase 58.11 1 8 8 27 6.738E8 31.65 50.45 7 13 1944.44 58.11 8 14 222 23.3 4.72 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 58.06 1 15 15 80 2.014E9 61.25 54.44 14 39 4600.76 58.06 15 41 360 39.6 4.39 HVO_1637 FKBP-type peptidylprolyl isomerase 57.52 1 10 11 72 5.862E9 56.53 49.02 10 34 5386.39 55.88 10 38 306 33.8 3.76 HVO_0861 SufB domain protein 57.46 1 17 17 125 3.976E9 121.72 53.98 16 63 9305.62 57.46 17 62 402 44.7 4.23 HVO_2015 conserved hypothetical protein 57.39 1 13 13 215 1.660E10 218.60 57.39 13 109 16080.43 50.14 12 106 345 37.7 4.25 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 57.22 1 14 14 188 9.066E9 160.39 49.34 13 92 10888.31 57.22 14 96 381 41.0 4.23 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 56.85 1 17 17 69 9.873E8 41.34 56.85 17 34 3719.78 56.85 17 35 336 38.0 4.61 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 56.77 1 15 15 156 6.075E9 188.46 56.77 15 78 12854.01 56.77 15 78 384 41.4 4.41 HVO_0870 proline--tRNA ligase 56.56 1 19 19 108 2.434E9 107.40 54.10 17 53 7407.93 56.56 19 55 488 54.9 4.44 HVO_2191 formyltetrahydrofolate deformylase 56.27 1 14 14 71 2.346E9 72.86 56.27 14 36 4880.68 56.27 14 35 327 36.2 4.63 HVO_0348 DNA-directed RNA polymerase subunit B' 55.99 1 25 25 175 2.661E9 168.19 55.83 24 86 11171.54 55.99 25 89 609 67.7 4.92 HVO_0025 thiosulfate sulfurtransferase 55.94 1 9 9 361 1.577E10 355.15 55.94 9 181 21441.88 55.94 9 180 286 32.1 4.28 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 55.36 1 16 16 99 1.736E9 90.42 55.36 16 50 6394.51 55.36 16 49 457 48.4 4.35 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 55.13 1 10 10 167 7.950E9 178.03 55.13 10 83 11322.74 55.13 10 84 312 34.5 4.98 HVO_2384 CBS domain protein 55.00 1 18 19 154 5.630E9 161.93 52.63 18 77 10222.78 53.68 18 77 380 42.5 5.01 HVO_2889 RecJ domain protein 54.87 1 28 28 225 6.157E9 224.93 52.67 27 111 15582.73 54.87 28 114 729 79.1 4.37 HVO_2435 peptidase M24 family protein 54.35 1 12 12 38 6.417E8 28.31 54.35 12 21 2274.84 51.09 11 17 368 40.0 4.53 HVO_0455 thermosome subunit 2 54.22 1 23 24 214 4.425E9 196.36 54.22 24 105 13352.62 54.22 24 109 557 59.3 4.37 HVO_A0207 CRISPR-associated protein Cas7 54.12 1 11 11 78 2.396E9 88.95 54.12 11 39 5388.58 54.12 11 39 340 38.2 4.54 HVO_2969 threonine synthase 53.94 1 18 18 108 3.043E9 97.15 53.94 18 54 6836.86 53.94 18 54 419 44.4 4.49 HVO_2204 "FtsZ family protein, type III" 53.92 1 16 19 98 3.340E9 101.64 51.65 18 48 7087.88 53.92 19 50 395 42.0 4.68 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 53.85 1 9 9 44 9.127E8 38.44 53.85 9 22 2492.63 53.85 9 22 286 31.2 4.54 HVO_0347 DNA-directed RNA polymerase subunit B'' 53.74 1 26 26 186 2.527E9 153.72 53.74 26 93 10964.67 52.78 25 93 521 58.9 5.00 HVO_0467 PhoU/TrkA-C domain protein 53.73 1 18 18 79 4.863E8 75.48 53.73 18 39 4810.33 53.73 18 40 402 43.3 4.49 HVO_2724 beta-lactamase domain protein 53.56 1 19 19 171 5.298E9 132.33 53.56 19 85 9931.52 53.56 18 86 450 50.1 5.40 HVO_0869 glutamate synthase large subunit 53.47 1 64 65 411 3.876E9 391.82 52.15 63 200 28323.29 53.47 65 211 1511 163.8 4.70 HVO_0240 Lrp/AsnC family transcription regulator 53.29 1 6 7 25 9.206E8 17.22 48.03 6 12 1447.00 47.37 6 13 152 16.9 4.39 HVO_1507 acetolactate synthase small subunit 53.21 1 9 9 34 2.708E8 32.83 53.21 9 17 2087.94 53.21 9 17 218 23.7 4.94 HVO_1189 aldehyde dehydrogenase 53.15 1 19 19 133 3.376E9 111.76 45.87 18 64 8338.31 53.15 19 69 508 56.1 4.59 HVO_0677 aspartate--tRNA ligase 53.00 1 16 16 266 8.319E9 289.68 53.00 16 136 18955.37 53.00 16 130 434 48.7 4.50 HVO_2588 isocitrate dehydrogenase (NADP) 52.51 1 19 19 181 1.081E10 191.67 49.40 18 88 12282.12 52.51 19 93 419 45.8 4.59 HVO_0104 DNA repair and recombination protein RadA 52.48 1 12 12 88 3.840E9 75.75 47.23 11 43 6677.03 52.48 12 45 343 37.3 4.64 HVO_0778 thermosome subunit 3 52.29 1 21 23 156 3.187E9 163.96 52.29 23 78 11275.75 52.29 23 78 524 55.2 4.59 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 52.12 1 12 12 84 2.937E9 56.18 48.26 11 40 5359.05 52.12 12 44 259 29.9 4.36 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 51.90 1 9 9 122 4.225E9 129.95 43.25 7 59 9046.28 51.90 9 63 289 29.8 4.27 HVO_2968 phosphoglycerate dehydrogenase 51.81 1 17 17 181 8.024E9 230.00 51.81 17 89 14684.35 49.14 16 92 525 55.3 4.36 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 51.80 1 15 15 68 3.369E9 57.04 46.89 14 32 4429.86 51.80 15 36 305 33.8 4.74 HVO_3007 malate dehydrogenase 51.64 1 14 14 213 9.048E9 188.10 37.83 13 106 10606.43 51.64 14 107 304 32.6 4.40 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 51.42 1 21 21 92 1.054E9 111.81 51.42 21 46 7571.20 51.42 21 46 599 65.3 4.51 HVO_0449 prephenate dehydratase 51.12 1 10 10 51 1.163E9 47.61 51.12 10 26 3180.91 51.12 10 25 268 28.7 4.64 HVO_1338 replication protein A 51.05 1 15 15 60 8.634E8 50.17 48.24 14 28 3347.49 51.05 15 32 427 46.0 4.36 HVO_2621 phosphoenolpyruvate carboxylase 50.61 1 35 35 234 2.834E9 209.83 50.61 35 117 15018.39 50.61 35 117 897 102.3 4.64 HVO_0859 FeS assembly ATPase SufC 50.50 1 12 12 118 3.653E9 86.50 50.50 12 58 7032.82 50.50 12 60 301 33.4 4.35 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 50.32 1 21 21 97 1.228E9 91.90 49.20 20 49 6703.91 48.40 20 48 626 67.6 4.65 HVO_1502 3-isopropylmalate dehydrogenase 50.31 1 12 12 91 1.672E9 72.61 42.59 11 41 6093.87 50.31 12 50 324 33.7 4.23 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 50.30 1 10 10 47 9.267E8 50.32 40.18 8 23 4252.79 50.30 10 24 336 36.8 4.12 HVO_0212 homolog to lactoylglutathione lyase 50.00 1 4 4 18 3.624E8 22.70 50.00 4 9 1408.93 50.00 4 9 124 13.5 4.13 HVO_1684 threonine--tRNA ligase 49.77 1 25 25 143 3.166E9 108.28 45.41 23 70 9153.25 49.77 25 73 643 73.4 4.45 HVO_1654 cysteine synthase 49.67 1 10 10 37 6.740E8 23.45 42.48 9 18 2115.88 49.67 10 19 306 32.3 4.32 HVO_0317 A-type ATP synthase subunit B 49.57 1 14 15 114 5.770E9 127.81 49.57 15 56 8419.55 49.57 15 58 468 51.9 4.25 HVO_1145 30S ribosomal protein S1e 49.55 1 10 10 44 8.196E8 50.08 49.55 10 22 3265.88 49.55 10 22 220 24.8 4.86 HVO_0393 UvrABC system protein A 49.54 1 35 35 143 6.502E8 136.26 48.73 34 71 9308.44 47.51 34 72 983 108.6 4.82 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 49.52 1 20 20 111 2.052E9 101.75 49.52 20 56 7331.77 49.52 20 55 624 67.6 4.27 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 49.48 1 10 10 118 3.901E9 115.89 49.48 10 59 8359.84 49.48 10 59 287 31.0 4.73 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 49.41 1 15 15 71 1.024E9 56.10 49.41 15 36 4616.30 49.41 15 35 340 38.8 4.58 HVO_0292 replication protein A 49.20 1 11 11 45 6.423E8 44.48 49.20 11 22 2968.37 49.20 11 23 311 34.6 4.31 HVO_2544 30S ribosomal protein S5 49.07 1 10 10 54 3.835E9 51.62 49.07 10 29 3518.48 46.73 9 25 214 23.3 9.29 HVO_0789 tryptophan synthase alpha subunit 48.74 1 8 8 46 6.447E8 45.05 44.04 7 23 2547.79 48.74 8 23 277 29.6 4.21 HVO_0661 dCTP deaminase (dUMP-forming) 48.72 1 6 6 24 1.892E8 15.22 48.72 6 12 1022.11 48.72 6 12 195 21.2 4.59 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 48.57 1 14 14 61 1.238E9 68.74 47.68 13 29 4039.61 48.57 14 32 453 47.5 4.63 HVO_0860 SufB domain protein 48.53 1 16 16 137 4.272E9 109.92 45.38 15 65 8717.37 41.81 15 72 476 53.2 4.69 HVO_2013 "FtsZ family protein, type III" 48.48 1 9 9 43 8.043E8 48.52 48.48 9 21 3133.19 42.64 8 22 394 41.5 4.61 HVO_0989 conserved hypothetical protein 48.41 1 8 8 31 3.567E8 10.00 42.06 7 15 1341.47 48.41 8 16 126 14.4 4.81 HVO_0874 beta-lactamase domain protein 48.13 1 24 24 98 2.372E9 80.04 45.78 23 48 6853.26 48.13 24 50 640 71.9 5.14 HVO_1459 ThuA family protein 47.90 1 5 5 31 1.158E9 31.74 47.90 5 16 2289.27 33.19 4 15 238 26.8 4.67 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 47.89 1 6 6 34 1.585E9 31.39 47.89 6 16 2306.89 47.89 6 18 190 20.6 4.30 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 47.86 1 19 19 340 1.598E10 339.93 46.59 18 169 24779.48 41.20 18 171 631 68.4 4.49 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 47.78 1 22 22 236 7.513E9 208.21 44.20 21 122 16120.83 47.78 22 114 586 64.0 4.49 HVO_0400 conserved hypothetical protein 47.62 1 3 3 9 9.237E7 4.25 47.62 3 5 189.88 47.62 3 4 126 13.9 4.68 HVO_1084 adenylosuccinate lyase 47.52 1 18 18 78 1.090E9 67.99 47.52 18 39 5424.12 42.98 17 39 463 50.8 4.70 HVO_1572 DNA gyrase subunit B 47.10 1 24 24 107 1.035E9 84.30 44.29 22 54 6592.79 47.10 24 53 639 71.2 4.83 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 46.79 1 10 10 70 2.661E9 98.79 45.00 9 34 5904.22 46.79 10 36 280 30.1 4.44 HVO_1132 adenylosuccinate synthase 46.73 1 19 19 181 5.747E9 148.98 43.57 18 89 11790.13 46.73 19 92 443 48.2 4.56 HVO_1973 conserved hypothetical protein 46.71 1 4 4 23 3.878E8 34.83 37.72 3 11 2108.47 46.71 4 12 167 18.1 4.36 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 46.50 1 16 16 85 1.128E9 80.77 41.61 15 42 5171.41 46.50 16 43 471 51.0 4.48 HVO_2059 NAD-dependent epimerase/dehydratase 46.45 1 10 10 54 1.894E9 34.09 46.45 10 27 3114.74 46.45 10 27 310 34.1 4.40 HVO_2700 AAA-type ATPase (CDC48 subfamily) 46.42 1 31 32 130 9.318E8 91.26 46.42 32 64 7267.26 46.42 32 66 754 82.8 4.75 HVO_0480 phosphoglycerate kinase 46.38 1 16 16 66 1.788E9 57.63 42.89 15 32 4190.02 46.38 16 34 401 43.6 4.37 HVO_A0205 CRISPR-associated endoribonuclease Cas6 46.32 1 11 11 53 1.174E9 62.04 46.32 11 27 4641.09 46.32 11 26 272 31.0 5.44 HVO_0999 DRTGG domain protein 46.30 1 12 12 66 1.132E9 46.84 46.30 12 33 3712.96 46.30 12 33 378 39.8 4.44 HVO_2783 30S ribosomal protein S4 46.29 1 9 9 47 1.401E9 39.91 46.29 9 23 3198.57 46.29 9 24 175 20.1 5.24 HVO_2646 dihydroxy-acid dehydratase 46.23 1 17 17 137 3.095E9 121.51 46.23 17 67 8448.67 46.23 17 70 584 61.8 4.42 HVO_0511 NAD-dependent epimerase/dehydratase 46.18 1 8 8 43 4.543E8 25.90 46.18 8 22 2082.52 35.88 7 21 262 29.3 4.78 HVO_0008 aspartate kinase 46.17 1 11 11 53 2.793E9 41.85 29.85 9 25 3040.02 46.17 11 28 392 41.7 4.46 HVO_0717 "cell division protein FtsZ, type I" 46.17 1 14 14 94 4.857E9 92.24 46.17 14 47 6526.10 46.17 14 47 379 39.8 4.40 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 45.84 1 13 13 61 1.137E9 63.21 42.92 12 30 4267.81 45.84 13 31 445 47.8 4.86 HVO_A0331 D-galactonate dehydratase 45.83 1 9 9 40 4.823E8 34.48 43.23 8 19 2279.32 45.83 9 21 384 42.8 4.83 HVO_B0118 SMC-like protein Sph2 45.81 1 29 29 165 2.533E9 159.66 45.81 29 85 10199.60 44.57 28 80 644 73.8 4.41 HVO_0024 thiosulfate sulfurtransferase 45.74 1 9 9 50 1.447E9 35.60 41.09 8 24 3491.35 45.74 9 26 258 28.4 4.30 HVO_2487 aspartate-semialdehyde dehydrogenase 45.64 1 9 9 82 4.355E9 72.57 45.64 9 39 4623.75 45.64 9 43 344 36.6 4.41 HVO_0829 peptidase S9 family protein 45.39 1 16 16 67 8.761E8 50.22 43.26 15 33 3586.86 45.39 16 34 608 67.4 4.54 HVO_1300 triosephosphate isomerase 45.33 1 6 6 46 2.837E9 46.81 45.33 6 23 3166.60 45.33 6 23 214 21.3 4.26 HVO_2726 glutamate--tRNA ligase 45.13 1 22 22 103 1.270E9 70.61 45.13 22 50 5470.68 45.13 22 53 585 65.2 4.58 HVO_1506 ketol-acid reductoisomerase 45.11 1 10 10 51 1.468E9 53.06 45.11 10 25 3200.64 45.11 10 26 348 37.9 4.34 HVO_0167 adenosylhomocysteinase 45.09 1 12 12 69 1.211E9 70.70 40.89 11 31 5813.95 45.09 12 38 428 46.6 4.39 HVO_1649 methionine adenosyltransferase 45.02 1 11 11 47 5.432E8 34.67 45.02 11 24 2835.77 45.02 11 23 402 43.5 4.45 HVO_0424 ABC-type transport system ATP-binding protein 44.70 1 19 19 113 7.793E8 117.57 42.72 18 54 7214.70 44.70 19 59 604 67.2 4.49 HVO_1955 aconitate hydratase 44.65 1 23 23 335 1.720E10 317.11 43.58 22 165 23555.13 44.65 23 170 654 70.4 4.45 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 44.63 1 12 12 46 3.635E8 41.75 42.15 11 23 3146.16 44.63 12 23 363 39.3 4.97 HVO_2624 CTP synthase 44.63 1 16 16 87 2.875E9 64.76 42.62 15 43 5230.68 44.63 16 44 549 60.8 4.70 HVO_0601 homoserine dehydrogenase 44.30 1 6 6 25 7.151E8 29.56 44.30 6 13 1990.05 31.01 5 12 316 32.2 4.25 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 44.30 1 16 16 71 1.172E9 75.20 39.87 14 34 4927.09 44.30 16 37 474 53.4 4.59 HVO_0809 methionine--tRNA ligase 44.19 1 22 22 117 1.673E9 122.03 44.19 22 56 8956.22 44.19 22 61 740 81.9 4.37 HVO_2130 IclR family transcription regulator 44.12 1 11 11 46 5.428E8 44.61 40.07 10 22 3267.93 44.12 11 24 272 30.1 5.55 HVO_1387 enoyl-CoA hydratase 43.97 1 8 8 27 3.988E8 13.67 39.30 7 13 1255.72 43.97 8 14 257 27.5 4.51 HVO_0388 homolog to ribonuclease R 43.96 1 17 17 84 6.364E8 95.08 43.96 17 42 6070.49 43.96 17 42 439 50.3 4.73 HVO_B0059 cobalt-precorrin 5A hydrolase 43.87 1 10 10 45 5.399E8 44.12 43.87 10 22 2590.79 43.87 10 23 326 34.5 4.51 HVO_2419 hydroxymethylglutaryl-CoA synthase 43.82 1 15 15 84 2.300E9 73.67 43.82 14 41 5088.09 43.82 15 43 445 50.1 4.64 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 43.76 1 14 14 39 8.212E8 27.49 30.23 12 18 2100.57 43.76 14 21 473 50.8 4.58 HVO_0203 replication factor C small subunit 43.73 1 13 13 59 8.098E8 52.55 41.90 12 27 3933.31 43.73 13 32 327 36.2 4.51 HVO_2225 AstE family protein 43.70 1 8 8 41 1.100E9 48.32 43.70 8 20 2702.26 43.70 8 21 341 36.9 4.53 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 43.60 1 17 17 67 2.367E8 59.45 43.60 17 33 4500.59 43.60 17 34 516 56.7 4.89 HVO_2348 GTP cyclohydrolase MptA 43.51 1 9 9 39 8.099E8 24.36 34.42 8 21 1473.92 43.51 9 18 308 33.5 4.68 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 43.37 1 10 10 42 7.729E8 28.22 40.33 9 20 2157.74 43.37 10 22 362 39.6 4.82 HVO_1082 homolog to orotate phosphoribosyltransferase 43.33 1 8 8 27 4.531E8 19.29 43.33 8 14 1591.32 43.33 8 13 210 22.3 4.42 HVO_0470 threonine synthase 43.32 1 9 9 28 1.731E8 19.78 32.43 7 13 1661.68 43.32 9 15 367 39.2 4.59 HVO_0118 50S ribosomal protein L20e 43.10 1 1 2 3 1.357E8 5.88 43.10 2 3 58 6.4 6.52 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 43.03 1 10 10 58 8.149E8 56.97 43.03 10 29 4093.65 43.03 10 29 330 36.3 4.35 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 42.93 1 6 6 28 3.675E8 23.89 37.50 5 12 1959.43 42.93 6 16 184 19.8 5.30 HVO_2552 30S ribosomal protein S4e 42.91 1 9 9 111 9.958E9 96.24 42.91 9 55 5850.33 42.91 9 56 247 26.6 4.58 HVO_A0496 UspA domain protein 42.76 1 10 10 50 1.398E9 41.57 42.76 10 25 3066.94 39.66 9 25 290 31.4 4.60 HVO_1541 glycerol kinase 42.55 1 16 16 116 4.462E9 111.77 39.22 15 57 7945.86 38.04 15 59 510 56.7 4.50 HVO_A0206 CRISPR-associated protein Cas8b 42.54 1 23 23 105 1.828E9 91.30 42.54 23 54 6319.28 39.75 22 51 717 79.3 4.60 HVO_0406 RNA-binding protein AU-1 42.52 1 13 13 52 2.725E9 37.18 42.52 13 26 2593.51 42.52 13 26 468 49.9 4.53 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 42.46 1 8 8 51 1.949E9 54.90 42.46 8 26 3998.35 42.46 8 25 252 26.0 4.39 HVO_2558 30S ribosomal protein S3 42.43 1 10 10 128 4.981E9 122.92 38.16 9 60 9807.14 42.43 10 68 304 33.4 4.06 HVO_2690 GFO family oxidoreductase 42.35 1 11 11 42 1.108E9 29.42 42.35 11 21 2510.20 37.16 10 21 366 40.0 4.60 HVO_0316 A-type ATP synthase subunit A 42.32 1 19 19 156 5.286E9 163.31 42.32 19 78 11109.98 42.32 19 78 586 64.5 4.25 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 42.29 1 15 15 86 3.376E9 82.64 40.38 14 41 5979.70 42.29 15 45 525 56.4 4.40 HVO_1212 KaiC-type circadian regulator CirA 42.28 1 10 10 52 2.581E9 62.83 42.28 10 26 4391.91 42.28 10 26 246 27.5 4.45 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 42.08 1 9 9 50 1.440E9 49.19 42.08 9 25 3470.19 42.08 9 25 259 28.0 4.50 HVO_2057 sugar nucleotidyltransferase 42.02 1 13 13 76 2.196E9 75.96 42.02 13 38 5266.75 39.78 12 38 357 37.8 4.44 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 42.01 1 38 38 203 2.311E9 182.30 40.46 36 99 13033.98 42.01 38 104 1033 114.3 4.45 HVO_2774 enolase 41.85 1 10 10 75 2.292E9 75.69 41.85 10 36 5595.12 41.85 10 39 399 42.0 4.37 HVO_0894 acyl-CoA synthetase 41.84 1 10 20 126 3.171E9 132.48 40.33 19 62 8598.78 41.84 20 64 662 74.3 4.48 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 41.84 1 7 7 28 3.010E8 30.23 41.84 7 14 1920.81 41.84 7 14 294 32.5 4.75 HVO_0196 conserved hypothetical protein 41.82 1 2 2 6 3.446E8 6.11 41.82 2 3 334.73 41.82 2 3 55 6.2 4.81 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 41.76 1 13 13 65 1.046E9 61.63 33.79 11 31 4690.97 41.76 13 34 364 39.3 4.35 HVO_2205 arNOG06768 family NADH-binding domain protein 41.53 1 9 9 31 2.113E8 38.16 41.53 9 16 2344.50 41.53 9 15 301 32.0 5.00 HVO_1031 thioredoxin-disulfide reductase 41.52 1 10 10 52 7.330E8 46.86 41.52 10 25 3671.39 41.52 10 27 342 37.4 4.46 HVO_2040 NAD-dependent epimerase/dehydratase 41.50 1 6 10 87 2.480E9 55.70 41.50 10 43 4989.83 41.50 10 44 306 33.8 4.51 HVO_2961 dihydrolipoyl dehydrogenase 41.47 1 13 13 68 9.081E8 76.26 36.00 12 33 5165.79 41.47 13 35 475 49.9 4.41 HVO_0911 GTP-binding protein Drg 41.46 1 12 12 47 2.500E8 39.16 41.46 12 24 2648.40 39.57 11 23 369 40.5 4.81 HVO_2454 anthranilate synthase component I 41.41 1 18 18 69 1.039E9 71.13 41.41 18 34 4907.24 41.41 18 35 524 55.9 4.56 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 41.38 1 11 11 75 2.784E9 64.04 37.01 10 37 4459.96 35.86 10 38 435 46.9 4.63 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 41.35 1 10 10 37 8.478E8 35.21 41.35 10 18 2600.12 41.35 10 19 266 27.8 4.84 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 41.19 1 13 13 58 4.849E8 47.48 41.19 13 29 2990.95 41.19 13 29 454 48.5 4.46 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 41.13 1 17 17 98 1.702E9 82.88 41.13 17 48 6151.64 41.13 17 50 496 55.0 4.53 HVO_2675 histidinol dehydrogenase 41.12 1 10 10 43 6.914E8 37.82 41.12 10 21 2836.94 41.12 10 22 428 45.4 4.50 HVO_1481 UspA domain protein 41.10 1 5 5 24 9.677E8 26.47 41.10 5 12 1671.75 41.10 5 12 163 17.7 4.40 HVO_1332 conserved hypothetical protein 41.09 1 4 4 13 4.450E8 8.76 32.56 3 6 801.23 41.09 4 7 129 14.9 4.16 HVO_0324 arginine--tRNA ligase 41.06 1 22 22 120 2.112E9 115.15 41.06 22 60 7506.96 38.16 21 60 587 65.0 4.35 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 40.93 1 18 19 95 1.068E9 95.08 38.36 18 47 5800.59 40.93 19 48 623 62.1 5.30 HVO_0980 NADH dehydrogenase-like complex subunit CD 40.93 1 14 19 105 2.102E9 78.98 40.93 19 52 5747.67 40.93 19 53 557 63.4 4.53 HVO_1690 DHH family phosphoesterase 40.82 1 12 12 66 5.769E8 66.15 40.82 12 32 5089.82 40.82 12 34 485 52.1 4.48 HVO_0206 alanine--tRNA ligase 40.78 1 30 30 158 1.064E9 123.97 39.91 29 77 10180.57 40.78 30 81 922 102.4 4.54 HVO_1284 GTP cyclohydrolase III 40.61 1 8 8 36 5.215E8 35.20 40.61 8 17 2825.63 40.61 8 19 261 28.9 4.70 HVO_1623 conserved hypothetical protein 40.60 1 8 8 30 3.223E8 25.36 40.60 8 15 1644.67 40.60 8 15 298 32.8 4.56 HVO_0792 3-dehydroquinate synthase type II 40.56 1 11 11 72 1.635E9 60.67 40.56 11 36 3793.34 40.56 11 36 392 43.1 4.44 HVO_2756 50S ribosomal protein L10 40.52 1 8 8 43 1.316E9 29.19 40.52 8 21 2296.50 40.52 8 22 348 36.9 3.99 HVO_0417 metal-dependent carboxypeptidase 40.44 1 15 15 61 1.324E9 47.75 34.26 12 29 4086.97 40.44 15 32 502 57.3 4.42 HVO_0109 cysteine desulfurase 40.38 1 13 13 58 8.930E8 66.99 40.38 13 29 4263.92 40.38 13 29 426 46.8 4.56 HVO_2861 conserved hypothetical protein 40.36 1 9 9 41 1.247E9 41.19 40.36 9 20 2475.46 40.36 9 21 275 29.1 4.27 HVO_2948 phenylalanine--tRNA ligase alpha subunit 40.28 1 9 9 41 1.133E9 49.70 40.28 9 21 2932.60 40.28 9 20 499 55.1 4.41 HVO_1306 chorismate synthase 40.26 1 11 11 69 6.225E8 73.89 40.26 11 35 4170.25 40.26 11 34 385 41.9 4.83 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 16 2.718E8 15.13 40.26 5 8 1050.88 40.26 5 8 154 17.5 4.50 HVO_1504 3-isopropylmalate dehydratase large subunit 40.17 1 16 17 99 3.370E9 102.33 40.17 17 50 7042.11 40.17 17 49 473 51.6 4.55 HVO_0353 30S ribosomal protein S12 40.14 1 8 8 32 1.192E9 33.08 40.14 8 16 1963.53 40.14 8 16 142 15.5 9.91 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 14 8.679E8 16.72 40.00 4 7 1127.56 40.00 4 7 130 14.1 4.79 HVO_0349 DNA-directed RNA polymerase subunit A' 39.86 1 30 30 159 2.042E9 140.95 39.86 30 79 10753.22 39.86 30 80 976 108.8 4.81 HVO_2981 uracil phosphoribosyltransferase 39.82 1 9 9 37 1.968E9 33.28 37.61 8 15 2762.48 39.82 9 22 226 24.5 4.49 HVO_0415 repair helicase 39.77 1 19 19 85 1.516E9 93.48 38.31 18 42 6450.21 39.77 19 43 616 69.6 4.70 HVO_1091 proteasome alpha subunit 39.68 1 9 10 57 1.949E9 63.42 39.68 10 29 4240.02 39.68 10 28 252 27.6 4.56 HVO_1854 histidine--tRNA ligase 39.68 1 15 15 81 1.300E9 57.63 39.68 15 41 5189.69 39.68 15 40 431 47.1 4.37 HVO_1545 dihydroxyacetone kinase subunit DhaL 39.66 1 7 7 41 1.125E9 35.21 39.66 7 20 2666.98 39.66 7 21 232 24.8 4.48 HVO_A0156 acyl-CoA synthetase 39.46 1 9 19 110 3.171E9 107.40 37.95 18 54 7295.45 39.46 19 56 664 74.0 4.40 HVO_0788 tryptophan synthase beta subunit 39.34 1 11 11 48 8.559E8 51.16 36.73 10 23 3588.29 39.34 11 25 422 45.7 4.65 HVO_1198 UspA domain protein 39.31 1 5 5 24 7.386E8 20.96 39.31 5 12 1713.59 39.31 5 12 145 15.6 4.75 HVO_1901 translation initiation factor aIF-2 gamma subunit 39.17 1 13 13 86 2.635E9 58.25 37.47 12 41 4610.46 39.17 13 45 411 43.9 4.36 HVO_2883 conserved hypothetical protein 39.17 1 19 19 66 3.256E8 57.08 36.89 17 32 4245.60 39.17 19 34 702 78.9 4.48 HVO_1125 cysteine--tRNA ligase 39.07 1 15 15 58 7.208E8 40.07 37.04 13 27 3548.19 37.04 14 31 494 55.2 4.56 HVO_0743 probable phosphodiesterase 38.98 1 20 20 113 2.637E9 85.93 38.98 20 56 6980.19 38.98 20 57 449 50.5 4.56 HVO_2759 peptidase M42 family protein 38.98 1 9 9 47 2.304E8 46.10 38.98 9 23 3350.65 38.98 9 24 354 37.0 4.40 HVO_2256 DUF262 family protein 38.96 1 17 17 51 5.198E8 26.48 33.98 15 25 2777.27 38.96 17 26 462 54.9 4.89 HVO_0243 threonine aldolase 38.71 1 10 10 45 4.261E8 45.24 38.71 10 22 3278.96 38.71 10 23 341 35.6 4.55 HVO_0313 A-type ATP synthase subunit E 38.66 1 5 5 30 5.780E8 46.01 31.44 4 15 2611.72 33.51 4 15 194 22.0 4.31 HVO_1018 RecJ domain protein 38.55 1 22 22 119 2.024E9 110.40 38.55 22 61 8449.50 35.55 21 58 633 69.8 4.58 HVO_2380 AAA-type ATPase (CDC48 subfamily) 38.49 1 20 20 62 2.650E8 47.93 36.07 18 30 3457.95 38.49 20 32 743 81.9 4.82 HVO_2790 ATP-binding protein Mrp 38.44 1 8 8 33 4.913E8 29.97 38.44 8 16 2082.80 38.44 8 17 346 36.8 4.50 HVO_2336 pyridoxal biosynthesis lyase PdxS 38.41 1 10 10 42 7.882E8 41.09 34.77 8 20 3357.32 38.41 10 22 302 32.5 4.81 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 38.33 1 20 20 93 9.204E8 85.76 35.17 18 44 6357.09 38.33 20 49 600 65.3 4.68 HVO_1571 DNA topoisomerase VI subunit B 38.22 1 22 22 109 7.764E8 80.07 35.84 21 55 5692.40 37.47 21 54 798 87.4 4.73 HVO_2536 CHP00300 family protein 38.22 1 8 8 23 3.915E8 13.03 38.22 8 12 855.69 33.89 7 11 416 44.8 4.51 HVO_0812 phosphoenolpyruvate synthase 38.11 1 25 25 84 5.913E8 80.24 36.93 24 42 5342.22 34.43 24 42 761 83.1 4.63 HVO_0536 ferritin 38.07 1 3 3 10 4.084E8 15.58 38.07 3 5 734.49 38.07 3 5 176 19.9 4.50 HVO_2716 acyl-CoA dehydrogenase 38.06 1 11 11 49 5.903E8 36.28 38.06 11 24 3296.50 38.06 11 25 381 41.3 4.65 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 114 2.131E9 117.79 35.50 8 56 7962.53 38.05 9 58 431 46.1 4.48 HVO_0694 probable phosphoribosyltransferase 37.97 1 7 7 30 3.471E8 35.30 37.97 7 15 2312.84 37.97 7 15 237 27.0 4.32 HVO_1568 alpha/beta hydrolase fold protein 37.91 1 7 7 26 1.539E8 10.83 33.57 6 12 1218.29 37.91 7 14 277 29.4 4.94 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 37.78 1 9 9 38 4.538E8 48.62 37.78 9 19 2726.28 37.78 9 19 270 29.1 4.35 HVO_C0069 GFO family oxidoreductase 37.65 1 10 10 47 4.364E8 50.88 37.65 10 24 2725.21 37.65 10 23 324 36.0 5.10 HVO_0314 A-type ATP synthase subunit C 37.36 1 11 11 53 1.537E9 49.04 33.33 10 25 3823.67 37.36 11 28 348 38.7 4.50 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.35 1 13 13 149 5.611E9 107.86 37.35 13 73 8126.22 37.35 12 76 332 34.8 4.22 HVO_2562 50S ribosomal protein L23 37.35 1 3 3 7 1.559E7 6.72 24.10 2 3 610.03 37.35 3 4 83 9.4 5.48 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 37.20 1 7 7 32 5.613E8 29.87 37.20 7 17 2127.43 37.20 7 15 336 36.0 4.51 HVO_0122 phosphoglycerate dehydrogenase 37.04 1 9 9 31 4.772E8 32.53 29.94 8 15 2214.50 36.73 8 16 324 35.3 5.35 HVO_1076 sugar nucleotidyltransferase 36.96 1 8 8 44 1.571E9 43.01 36.96 8 22 3080.65 36.96 8 22 322 35.8 4.20 HVO_1590 DnaK-type molecular chaperone Hsp70 36.80 1 19 19 156 4.783E9 148.87 36.80 19 80 10672.71 36.80 19 76 625 67.2 4.18 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 36.77 1 11 11 38 6.809E8 30.07 36.77 11 19 2120.69 33.49 10 19 427 45.4 4.56 HVO_0806 pyruvate kinase 36.75 1 14 14 87 2.142E9 93.59 36.75 14 43 6088.49 32.65 13 44 585 62.0 4.54 HVO_A0273 ThuA family protein 36.71 1 4 4 11 1.077E8 7.73 36.71 4 5 695.86 24.89 3 6 237 26.5 4.77 HVO_A0406 conserved hypothetical protein 36.54 1 2 10 44 9.659E8 24.02 36.54 10 24 2196.34 36.54 10 20 405 44.4 5.30 HVO_2333 conserved hypothetical protein 36.36 1 9 9 28 2.089E8 19.31 36.36 9 14 1185.16 36.36 9 14 308 34.9 4.54 HVO_2436 malic enzyme (NADP) 36.22 1 18 22 112 1.142E9 139.42 36.22 22 57 8947.66 36.22 22 55 751 81.4 4.55 HVO_1531 UDP-glucose 6-dehydrogenase 36.05 1 12 12 44 6.104E8 40.48 36.05 12 23 2945.20 26.74 10 21 430 45.9 4.50 HVO_2813 RimK family protein 35.98 1 13 13 97 2.454E9 84.47 33.77 12 47 6177.82 35.98 13 50 453 49.0 4.73 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 35.92 1 11 11 49 1.428E9 52.85 35.92 11 24 3099.23 35.92 11 25 348 38.2 4.32 HVO_2481 HD family hydrolase 35.90 1 9 11 38 1.952E8 23.47 35.90 11 19 1883.72 30.26 10 19 390 42.7 6.14 HVO_1172 NAD-dependent epimerase/dehydratase 35.87 1 10 10 36 2.310E9 29.84 33.33 9 17 2363.82 35.87 10 19 315 34.9 4.34 HVO_1575 arginase 35.79 1 6 6 24 4.917E8 18.16 35.79 6 12 1374.84 35.79 6 12 299 31.0 4.58 HVO_0997 peptidase M24 family protein 35.60 1 8 8 30 1.963E8 21.83 35.60 8 15 1865.47 35.60 8 15 368 39.9 4.49 HVO_1164 HD family hydrolase 35.56 1 8 8 34 5.695E8 26.26 31.48 7 16 2178.26 35.56 8 18 270 29.8 4.87 HVO_0321 peptide chain release factor aRF-1 35.51 1 14 14 54 6.333E8 31.31 33.33 13 27 3167.24 35.51 14 27 414 46.6 4.83 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 35.38 1 6 6 22 5.047E8 16.51 31.41 5 9 1389.62 35.38 6 13 277 30.6 4.30 HVO_0549 2-keto-3-deoxygluconate kinase 35.31 1 9 10 40 7.850E8 37.86 31.56 9 19 2928.49 35.31 10 21 320 34.1 4.34 HVO_2721 amidophosphoribosyltransferase 35.29 1 11 11 52 1.598E9 49.29 35.29 11 26 3205.24 35.29 11 26 493 53.4 4.78 HVO_C0001 Orc1-type DNA replication protein 35.29 1 11 11 43 2.896E8 35.89 33.58 10 22 2314.69 35.29 11 21 408 45.2 4.97 HVO_0138 tyrosine--tRNA ligase 35.06 1 7 7 40 1.420E9 24.44 35.06 7 20 2286.79 35.06 7 20 328 36.1 4.34 HVO_0541 aconitate hydratase 34.97 1 22 22 87 1.122E9 60.09 33.90 21 43 4914.80 34.01 21 44 938 102.1 4.40 HVO_1123 thioredoxin-disulfide reductase 34.96 1 9 9 44 1.396E9 29.53 31.81 8 20 2999.72 34.96 9 24 349 37.3 4.32 HVO_1348 probable YjeF family carbohydrate kinase 34.94 1 12 12 39 2.504E8 36.92 32.22 11 19 2364.88 34.94 12 20 478 48.8 4.45 HVO_A0636 YbaK domain protein 34.81 1 3 3 11 2.431E8 15.83 34.81 3 6 852.97 34.81 3 5 158 16.7 4.54 HVO_0848 endonuclease III 34.80 1 6 6 16 7.722E7 4.57 34.80 6 8 539.69 34.80 6 8 227 25.5 4.55 HVO_2706 translation initiation factor aIF-2B delta subunit 34.75 1 7 7 29 7.416E8 24.94 34.75 7 14 1684.97 34.75 7 15 282 30.7 4.42 HVO_1140 acyl-CoA dehydrogenase 34.74 1 11 11 42 5.219E8 45.45 34.74 11 21 3011.47 34.74 11 21 380 41.2 4.55 HVO_1025 acetyl-CoA C-acyltransferase 34.73 1 9 9 56 7.217E8 55.07 34.73 9 28 3882.85 34.73 9 28 383 40.7 4.56 HVO_1080 conserved hypothetical protein 34.57 1 4 4 15 4.308E8 12.24 34.57 4 7 965.56 34.57 4 8 188 21.1 4.31 HVO_2908 dihydropteroate synthase 34.56 1 9 9 34 2.832E8 34.57 29.29 8 17 2123.95 34.56 9 17 379 40.8 4.53 HVO_2947 phenylalanine--tRNA ligase beta subunit 34.56 1 14 14 59 1.652E9 41.75 28.95 10 27 3812.83 34.56 14 32 570 63.3 4.46 HVO_1824 conserved hypothetical protein 34.50 1 11 11 39 5.253E8 41.65 33.57 10 19 2765.74 34.50 11 20 429 47.4 4.20 HVO_0729 inorganic pyrophosphatase 34.46 1 7 7 48 2.518E9 44.47 34.46 7 24 3436.79 34.46 7 24 177 20.4 4.16 HVO_1465 naphthoate synthase 34.43 1 8 8 24 3.473E8 20.63 30.49 7 11 1529.61 34.43 8 13 305 33.9 4.83 HVO_1778 catalase-peroxidase 34.40 1 17 17 92 2.292E9 102.92 31.75 16 44 6506.22 34.40 17 48 718 80.0 4.31 HVO_2417 conserved hypothetical protein 34.36 1 5 5 23 7.455E8 22.01 34.36 5 12 1445.70 26.67 4 11 195 21.6 3.65 HVO_1932 2-D-hydroxyacid dehydrogenase 34.09 1 9 9 36 3.267E8 40.31 34.09 9 18 2624.75 34.09 9 18 308 33.0 4.60 HVO_1867 lysine--tRNA ligase 33.87 1 15 15 55 4.501E8 38.54 33.87 15 28 2822.39 32.79 14 27 555 62.1 4.46 HVO_1079 sulfate adenylyltransferase small subunit 33.85 1 8 8 30 4.352E8 36.99 23.69 7 15 2121.49 32.00 7 15 325 37.5 4.18 HVO_2708 YfiH family protein 33.85 1 7 7 26 1.072E9 39.76 33.85 7 13 2617.53 33.85 7 13 322 35.4 4.35 HVO_1660 DisA-N domain protein 33.83 1 7 7 30 6.089E8 38.40 33.83 7 15 2173.44 33.83 7 15 269 28.9 4.73 HVO_2425 GNAT family acetyltransferase 33.80 1 6 6 23 3.614E8 22.95 33.80 6 11 1564.38 33.80 6 12 216 24.4 4.54 HVO_0041 ornithine carbamoyltransferase 33.78 1 6 6 30 7.053E8 32.99 33.78 6 15 1859.90 33.78 6 15 299 32.7 4.37 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 33.78 1 11 11 69 8.804E8 61.17 33.78 11 35 4189.15 33.78 11 34 447 48.5 4.56 HVO_B0114 IclR family transcription regulator 33.73 1 8 8 30 1.919E8 25.61 33.73 8 15 1751.59 33.73 8 15 252 28.4 5.44 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 33.60 1 6 6 30 7.043E8 14.70 28.85 5 14 1717.82 33.60 6 16 253 26.0 4.60 40354192 keratin 10 [Homo sapiens] 33.56 1 0 21 82 1.185E9 72.10 33.56 21 41 5032.88 33.56 21 41 584 58.8 5.16 HVO_2156 UspA domain protein 33.55 1 6 6 24 7.261E8 23.07 33.55 6 12 1823.58 33.55 6 12 301 31.6 4.69 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 33.51 1 4 4 30 6.966E8 12.12 33.51 4 15 1265.23 33.51 4 15 188 20.5 4.60 HVO_0358 homoserine dehydrogenase 33.44 1 5 6 34 8.421E8 36.25 33.44 6 17 2092.46 33.44 6 17 317 32.4 4.44 HVO_2712 3'-5' RNA ligase 33.13 1 12 12 50 4.205E8 33.30 33.13 12 25 2805.15 31.89 11 25 486 53.4 4.92 HVO_1816 dihydroorotase 33.10 1 10 10 37 2.387E8 32.68 33.10 10 19 2278.16 33.10 10 18 429 45.4 4.40 HVO_A0092 acyl-CoA dehydrogenase 33.07 1 8 8 33 2.580E8 14.40 33.07 8 16 1396.44 33.07 8 17 381 42.2 4.83 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 33.05 1 0 21 82 1.185E9 72.10 33.05 21 41 5032.88 33.05 21 41 593 59.5 5.21 HVO_1327 AAA-type ATPase (CDC48 subfamily) 33.02 1 16 17 69 4.620E8 40.75 31.39 16 34 3471.07 33.02 17 35 736 78.1 4.88 HVO_0401 UspA domain protein 32.89 1 4 4 14 5.954E8 9.06 25.00 3 6 876.53 32.89 4 8 152 16.4 4.79 HVO_1370 gamma-glutamyl phosphate reductase 32.88 1 13 13 78 1.077E9 61.39 32.88 13 39 4679.60 32.88 13 39 444 48.1 4.34 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 32.74 1 7 7 52 9.802E8 51.57 32.74 7 26 3744.14 32.74 7 26 226 25.5 4.25 HVO_1508 acetolactate synthase large subunit 32.71 1 10 10 43 9.367E8 48.58 32.71 10 22 2967.01 27.26 9 21 587 62.3 4.36 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 32.71 1 5 5 22 6.145E8 15.34 32.71 5 11 1091.09 32.71 5 11 269 28.3 4.49 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 32.68 1 5 5 14 4.777E8 9.16 32.68 5 7 766.51 32.68 5 7 254 26.9 4.42 HVO_2913 superoxide dismutase (Mn) 32.66 1 0 4 21 3.906E9 20.92 32.66 4 11 1552.63 32.66 4 10 199 22.3 4.48 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 32.51 1 12 12 59 1.127E9 49.43 32.51 12 30 3343.82 26.81 11 29 526 57.2 4.31 HVO_A0475 superoxide dismutase (Mn) 32.50 1 0 4 21 3.906E9 20.92 32.50 4 11 1552.63 32.50 4 10 200 22.4 4.45 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 32.47 1 6 6 22 3.601E8 18.72 32.47 6 11 1294.86 32.47 6 11 231 25.0 4.25 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 32.43 1 11 11 72 3.271E9 67.95 32.43 11 36 4756.45 32.43 11 36 370 41.9 4.48 47132620 keratin 2a [Homo sapiens] 32.39 1 12 18 66 1.642E9 61.40 32.39 18 33 4826.64 32.39 18 33 639 65.4 8.00 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 32.23 1 11 11 35 8.829E8 35.76 32.23 11 18 2263.72 27.34 10 17 512 53.8 4.78 HVO_2619 ubiquitin-like modifier protein SAMP1 32.18 1 2 2 2 1.213E8 57.21 32.18 2 2 87 8.9 4.26 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 32.17 1 9 9 36 1.433E9 24.96 32.17 9 18 2074.39 32.17 9 18 373 40.2 4.44 HVO_2952 tRNA-splicing endonuclease 32.15 1 7 7 26 1.968E8 23.11 32.15 7 14 1539.09 32.15 7 12 339 37.4 4.74 17318569 keratin 1 [Homo sapiens] 32.14 1 1 22 158 2.290E9 162.53 32.14 22 79 10980.60 32.14 22 79 644 66.0 8.12 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 32.14 1 18 19 85 1.410E9 60.65 32.14 19 42 4886.65 32.14 19 43 697 74.5 4.13 HVO_0519 replication protein A 32.09 1 12 12 51 7.318E8 47.87 32.09 12 25 3309.82 32.09 12 26 483 51.0 4.13 HVO_1391 NUDIX family hydrolase 31.79 1 4 4 8 7.332E7 7.90 31.79 4 4 578.90 31.79 4 4 151 17.4 5.01 HVO_A0266 IclR family transcription regulator 31.76 1 7 7 29 2.943E8 30.61 27.84 6 14 1839.20 31.76 7 15 255 27.7 6.05 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 31.69 1 10 10 43 3.468E8 28.36 28.49 9 21 2418.78 31.69 10 22 344 39.1 4.73 HVO_A0432 conserved hypothetical protein 31.60 1 1 9 38 9.096E8 24.02 31.60 9 20 2026.18 31.60 9 18 405 44.5 5.24 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 18 2.383E9 20.36 31.45 3 9 1336.30 31.45 3 9 124 14.2 5.22 HVO_B0382 TATA-binding transcription initiation factor 31.38 1 4 4 12 2.723E8 13.73 31.38 4 6 881.11 31.38 4 6 188 20.1 4.12 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 31.35 1 6 6 20 6.145E8 22.26 31.35 6 10 1327.57 31.35 6 10 386 42.1 4.49 HVO_1134 conserved hypothetical protein 31.31 1 15 15 64 5.268E8 46.60 31.31 15 32 3774.98 31.31 15 32 757 80.6 4.35 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 31.23 1 8 8 31 4.222E8 35.09 31.23 8 15 2602.14 31.23 8 16 333 36.7 4.56 HVO_0049 argininosuccinate synthase 31.11 1 11 11 51 2.867E9 45.82 31.11 11 25 3029.68 30.62 10 26 405 44.5 4.34 HVO_1847 oligoendopeptidase PepF 31.05 1 13 13 56 4.723E8 46.92 31.05 13 27 3332.64 31.05 13 29 599 68.5 4.41 HVO_B0018 ParA domain protein 31.01 1 5 5 19 1.931E8 14.93 31.01 5 10 1185.87 31.01 5 9 287 31.7 4.74 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 30.89 1 8 8 28 2.657E8 14.04 27.22 7 13 1722.50 30.89 8 15 327 36.0 4.73 HVO_1562 proteasome beta subunit 30.86 1 5 5 24 3.456E8 16.62 30.86 5 12 1268.99 30.86 5 12 243 26.0 4.63 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 48 1.565E9 40.28 25.06 7 24 2926.64 30.84 8 24 415 44.4 4.41 HVO_2008 archaeosine synthase 30.77 1 13 13 45 8.726E8 34.09 29.06 12 22 2619.56 30.77 13 23 585 64.9 4.81 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 30.75 1 0 21 154 2.290E9 158.46 30.75 21 77 10786.66 30.75 21 77 644 66.0 8.12 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 30.68 1 7 7 18 1.101E9 18.36 23.30 5 8 1198.50 27.14 6 10 339 38.1 4.50 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 30.57 1 7 7 19 1.547E8 9.83 30.57 7 9 838.48 30.57 7 10 386 40.0 4.68 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 30.34 1 4 5 12 5.651E8 4.35 13.11 3 5 560.62 30.34 5 7 267 29.1 4.63 HVO_1553 hydroxypyruvate reductase 30.32 1 10 10 34 1.637E8 22.08 30.32 10 17 1770.79 30.32 10 17 442 45.2 4.50 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 30.30 1 7 7 42 1.982E9 34.82 25.59 6 19 2446.29 30.30 7 23 297 31.3 4.36 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 30.28 1 11 11 37 2.167E8 31.83 30.28 11 19 2213.51 28.10 10 18 459 50.5 4.63 HVO_1967 glucose-6-phosphate isomerase 30.23 1 9 9 38 5.124E8 34.65 30.23 9 19 2830.56 30.23 9 19 430 45.6 4.40 HVO_2951 tryptophan--tRNA ligase 30.06 1 13 13 46 4.275E8 29.43 25.90 12 22 1908.26 26.28 12 24 529 59.1 4.53 HVO_2773 30S ribosomal protein S2 30.00 1 4 4 41 3.873E9 44.20 30.00 4 21 2861.97 30.00 4 20 260 28.3 4.16 HVO_A0003 ParA domain protein 29.93 1 6 6 18 1.190E8 13.19 29.93 6 9 903.11 29.93 6 9 274 30.3 4.53 HVO_0681 DNA topoisomerase I 29.76 1 19 19 68 3.941E8 53.05 27.02 17 33 3994.03 29.76 19 35 840 93.6 4.58 HVO_1236 acyl-CoA synthetase 29.72 1 12 12 44 6.102E8 35.68 29.72 11 21 3082.39 29.72 12 23 535 59.1 4.60 HVO_1573 DNA gyrase subunit A 29.70 1 21 21 95 1.269E9 105.98 27.96 19 46 6819.16 29.70 21 49 862 94.8 4.56 HVO_1133 conserved hypothetical protein 29.70 1 2 2 3 1.924E8 357.91 29.70 2 3 101 11.7 4.58 HVO_2338 homoserine kinase 29.69 1 4 4 13 1.489E8 5.47 25.60 3 6 462.94 29.69 4 7 293 29.8 4.88 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 29.67 1 7 7 25 2.729E8 19.54 29.67 7 13 1288.77 24.33 6 12 337 35.9 4.69 HVO_1478 transcription initiation factor TFB 29.65 1 5 9 48 1.172E9 41.07 29.65 9 24 3302.38 29.65 9 24 317 35.7 5.47 HVO_1804 nicotinate phosphoribosyltransferase 29.64 1 8 8 22 2.891E8 20.46 26.55 7 10 1367.16 29.64 8 12 388 41.1 4.60 HVO_2648 phosphoglycerate dehydrogenase 29.47 1 6 6 19 2.575E8 11.12 29.47 6 10 1026.22 25.08 5 9 319 34.2 4.64 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 29.39 1 8 8 47 8.417E8 53.46 23.34 7 23 3431.43 29.39 8 24 347 36.8 4.93 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 29.38 1 7 7 19 2.348E8 8.31 29.38 7 10 587.00 29.38 7 9 422 43.6 4.72 HVO_1577 conserved hypothetical protein 29.38 1 5 5 16 3.466E8 9.81 29.38 5 8 842.50 29.38 5 8 177 19.4 4.74 HVO_1488 D-gluconate dehydratase 29.37 1 8 10 65 1.582E9 58.32 25.73 9 32 4148.27 29.37 10 33 412 45.8 4.60 HVO_0350 DNA-directed RNA polymerase subunit A'' 29.36 1 11 11 49 2.829E9 51.92 29.36 11 25 3646.61 24.58 10 24 419 46.1 4.35 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 29.32 1 8 8 39 3.776E8 35.03 29.32 8 19 2605.84 29.32 8 20 324 36.6 4.68 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 29.28 1 13 13 62 1.086E9 44.23 29.28 13 32 3654.02 27.33 12 30 461 50.7 4.73 HVO_2688 TrmB family transcription regulator 29.18 1 8 8 36 2.085E9 45.39 29.18 8 18 3174.91 29.18 8 18 353 39.3 4.58 HVO_1235 creatininase 29.17 1 5 5 14 1.532E8 8.09 29.17 5 7 832.58 29.17 5 7 264 29.2 4.84 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 29.02 1 8 8 25 1.355E8 14.22 22.69 7 12 1385.27 29.02 8 13 379 41.7 4.83 HVO_2918 thymidylate synthase 28.92 1 6 6 20 2.414E8 17.65 28.92 6 10 1353.11 28.92 6 10 332 37.5 4.61 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 28.85 1 7 7 20 3.090E8 16.36 23.61 6 10 1070.16 26.89 6 10 305 34.1 4.91 HVO_0658 tRNA pseudouridine(13) synthase TruD 28.73 1 8 8 30 2.439E8 26.29 28.73 8 15 1622.55 28.73 8 15 463 50.6 4.70 HVO_1914 acetyl-CoA C-acyltransferase 28.65 1 7 7 34 6.201E8 32.68 28.65 7 17 2425.60 28.65 7 17 377 39.9 4.41 HVO_1593 PAC2 family protein 28.63 1 3 3 8 3.496E8 7.27 28.63 3 4 425.71 28.63 3 4 248 26.6 4.46 HVO_2879 ornithine cyclodeaminase 28.61 1 6 6 19 2.410E9 14.91 16.87 4 7 1571.01 28.61 6 12 332 34.6 4.45 HVO_0552 DNA mismatch repair protein MutS 28.57 1 20 20 67 4.384E8 58.07 27.16 19 33 3851.82 26.62 19 34 924 99.2 4.65 HVO_1547 isoleucine--tRNA ligase 28.57 1 19 19 97 1.382E9 85.46 28.57 19 48 5846.49 26.17 18 49 1043 117.9 4.30 HVO_0431 HAD superfamily hydrolase 28.52 1 5 5 13 3.415E8 4.68 28.52 5 7 360.61 22.89 4 6 284 30.4 4.26 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 28.51 1 9 9 31 2.314E8 14.68 28.51 9 15 1703.52 28.51 9 16 442 46.9 4.58 HVO_2580 L-aspartate oxidase 28.49 1 12 12 56 4.542E8 44.33 28.49 12 29 3436.99 26.63 11 27 537 55.8 4.63 HVO_2912 ThiJ/PfpI domain protein 28.36 1 3 3 14 1.435E8 11.27 28.36 3 8 671.29 28.36 3 6 201 20.9 4.36 HVO_1871 UPF0447 family protein 28.34 1 14 14 72 1.054E9 55.00 24.95 13 35 4002.06 28.34 13 37 501 56.1 4.59 HVO_2643 NADPH:quinone reductase 28.32 1 8 8 48 9.026E8 38.22 28.32 8 24 3054.78 28.32 8 24 346 37.2 4.55 HVO_2370 HAD superfamily hydrolase 28.31 1 2 2 2 3.691E8 0.00 28.31 2 2 219 23.4 4.78 HVO_1625 conserved hypothetical protein 28.29 1 11 11 37 3.480E8 39.69 28.29 11 19 2526.31 26.91 10 18 654 70.1 4.04 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 28.29 1 8 8 37 6.879E8 24.05 25.77 7 18 2082.96 28.29 8 19 357 39.8 4.41 HVO_1491 HAD superfamily hydrolase 28.19 1 10 10 41 3.612E8 34.25 28.19 10 20 2623.76 28.19 10 21 408 44.4 4.60 HVO_B0375 Spo0M family protein 28.16 1 4 4 12 1.392E8 13.43 28.16 4 6 809.86 28.16 4 6 245 27.2 4.35 HVO_A0388 Lrp/AsnC family transcription regulator 28.16 1 4 4 9 1.187E8 4.87 28.16 4 5 329.98 28.16 4 4 174 20.1 4.86 HVO_2188 phosphoribosylformylglycinamidine synthase 1 28.13 1 5 5 21 6.315E8 20.82 28.13 5 10 1489.41 28.13 5 11 224 23.9 4.36 HVO_1576 NAD-dependent epimerase/dehydratase 28.10 1 4 8 51 1.868E9 40.86 28.10 8 25 3228.68 28.10 8 26 306 33.9 4.51 HVO_1412 diphosphomevalonate decarboxylase 28.09 1 9 9 50 2.191E9 29.51 28.09 9 25 2686.14 28.09 9 25 324 35.4 4.78 HVO_2427 replication factor C large subunit 28.07 1 12 12 39 2.456E8 40.05 28.07 12 20 2255.68 28.07 12 19 488 53.4 4.67 HVO_0328 NAD-dependent epimerase/dehydratase 28.04 1 5 5 23 7.954E7 10.83 28.04 5 12 1163.17 28.04 5 11 296 31.7 5.07 HVO_0357 ACT domain protein 28.04 1 5 5 27 8.765E8 22.23 28.04 5 14 1582.01 28.04 5 13 189 20.2 4.59 HVO_1657 phosphoribosylamine--glycine ligase 28.04 1 9 9 48 2.352E9 38.88 25.23 8 23 2954.25 28.04 9 25 428 45.5 4.20 HVO_0452 leucine--tRNA ligase 27.97 1 20 20 74 8.469E8 66.12 25.99 18 36 4849.93 27.97 20 38 958 109.5 4.37 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 27.88 1 28 28 118 7.285E8 77.01 27.88 28 59 5944.88 27.26 26 59 1284 141.2 4.35 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 27.87 1 6 6 14 1.095E8 14.63 24.59 5 6 790.05 27.87 6 8 305 32.7 4.56 HVO_2960 dihydrolipoamide S-acyltransferase 27.83 1 11 11 47 3.177E8 57.99 27.83 11 23 3577.50 27.83 11 24 521 54.9 4.40 HVO_2467 NADPH:quinone reductase 27.73 1 6 6 32 4.959E8 27.15 27.73 6 16 2076.55 27.73 6 16 321 33.0 4.51 HVO_1291 fumarylacetoacetase family protein 27.57 1 5 5 23 1.007E9 27.27 25.51 4 11 1605.72 27.57 5 12 243 26.3 4.55 HVO_B0001 Orc1-type DNA replication protein 27.56 1 10 10 27 2.174E8 20.23 27.56 10 13 1475.32 27.56 10 14 410 45.8 5.33 HVO_2239 UspA domain protein 27.46 1 4 4 12 4.676E8 5.74 27.46 4 6 496.14 27.46 4 6 142 15.4 4.16 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 27.32 1 5 5 24 5.390E8 23.04 27.32 5 11 1264.86 27.32 5 13 377 39.2 4.18 HVO_2614 uridine phosphorylase 27.27 1 4 4 24 1.451E9 20.89 17.77 3 11 1329.92 27.27 4 13 242 25.8 4.30 HVO_0573 endonuclease IV 27.15 1 5 5 22 1.065E9 14.92 27.15 5 11 1606.13 27.15 5 11 291 31.4 4.44 HVO_0156 "tRNA (guanine(10),N(2))-dimethyltransferase" 27.10 1 7 7 19 6.307E7 15.38 27.10 7 10 813.68 27.10 6 9 321 34.2 5.25 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 26.92 1 4 4 21 2.743E8 26.25 26.92 4 11 1708.35 26.92 4 10 208 22.6 4.36 HVO_0214 L-lactate dehydrogenase 26.88 1 8 8 50 2.952E9 49.91 26.88 8 26 3124.93 19.69 6 24 320 34.5 4.49 HVO_A0458 ParA domain protein 26.80 1 5 5 14 2.337E8 11.32 26.80 5 7 821.58 26.80 5 7 291 32.2 4.79 HVO_1097 diaminopimelate epimerase 26.74 1 5 5 17 1.953E8 26.23 23.26 4 8 1466.63 26.74 5 9 288 29.9 4.48 HVO_1503 3-isopropylmalate dehydratase small subunit 26.73 1 4 4 16 3.082E8 10.37 17.82 3 7 825.68 26.73 4 9 202 22.0 4.15 HVO_1199 acyl-CoA dehydrogenase 26.58 1 6 6 16 9.982E7 10.78 26.58 6 8 665.12 26.58 6 8 380 41.5 4.64 HVO_0867 HD family hydrolase 26.52 1 6 6 25 1.877E8 21.27 26.52 6 12 1643.79 26.52 6 13 230 26.2 4.78 HVO_0194 Orc1-type DNA replication protein 26.47 1 8 8 23 2.472E8 9.95 26.47 8 12 977.76 24.60 7 11 374 42.2 4.94 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 26.43 1 22 22 97 1.075E9 93.79 25.69 21 48 7302.21 26.43 22 49 1082 117.2 4.32 HVO_1020 HEAT-PBS family protein 26.25 1 9 9 34 4.754E8 36.87 26.25 9 17 2604.29 26.25 9 17 419 45.5 3.95 HVO_2781 DNA-directed RNA polymerase subunit D 26.25 1 5 5 39 1.660E9 23.64 26.25 5 19 2333.52 26.25 5 20 259 28.1 4.32 HVO_1570 DNA topoisomerase VI subunit A 26.23 1 7 7 28 5.910E8 14.96 26.23 7 14 1422.99 26.23 7 14 366 41.8 4.63 HVO_1685 conserved hypothetical protein 26.22 1 12 12 45 3.430E8 23.76 26.22 12 22 2114.31 26.22 12 23 492 54.5 5.74 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 14 1.342E8 12.09 26.15 3 7 806.89 26.15 3 7 130 13.4 8.56 HVO_2496 adenylate kinase 25.96 1 4 4 20 1.074E9 21.99 25.96 4 10 1512.14 25.96 4 10 208 23.1 4.25 HVO_0466 citrate (si)-synthase 25.86 1 9 9 73 3.642E9 93.46 25.86 9 37 5601.01 25.86 9 36 379 41.8 4.55 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 25.78 1 6 6 24 2.067E8 19.69 25.78 6 12 1166.98 25.78 6 12 287 31.8 4.93 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 25.69 1 10 11 52 7.272E8 46.36 23.58 10 26 3290.07 25.69 11 26 615 67.6 4.88 7428712 "keratin 1, type II, cytoskeletal - human" 25.66 1 0 18 135 2.189E9 140.67 25.66 18 68 9574.73 25.66 18 67 643 65.5 6.35 HVO_1698 CBS/parB domain protein 25.66 1 5 6 17 1.450E8 4.83 25.66 6 9 551.93 23.77 5 8 265 29.4 4.92 HVO_A0485 aminotransferase class V 25.64 1 6 6 25 4.124E8 17.78 19.66 5 12 1390.48 25.64 6 13 351 37.3 4.26 HVO_2717 alanine--tRNA ligase 25.63 1 8 8 31 1.948E8 28.84 22.61 7 15 1918.91 25.63 8 16 398 41.6 4.39 HVO_1356 sensor box histidine kinase 25.45 1 9 9 23 2.345E8 24.66 23.09 8 11 1277.13 25.45 9 12 550 61.1 4.60 HVO_2068 "FtsZ family protein, type III" 25.41 1 5 5 16 4.592E8 23.61 25.41 5 8 1634.78 25.41 5 8 370 38.7 4.49 HVO_C0042 helicase domain protein 25.35 1 28 28 100 6.308E8 94.02 24.33 27 50 6494.44 25.35 28 50 1274 144.4 4.67 HVO_1880 conserved hypothetical protein 25.33 1 5 5 17 8.615E7 15.35 25.33 5 9 965.10 20.00 4 8 225 23.8 4.59 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 25.28 1 5 5 15 3.094E8 16.38 18.87 4 7 1132.17 25.28 5 8 265 28.7 4.87 HVO_1727 TATA-binding transcription initiation factor 25.27 1 5 5 23 1.631E9 17.75 25.27 5 12 1611.20 25.27 5 11 186 19.9 4.36 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 25.25 1 4 4 10 7.123E7 9.05 25.25 4 5 601.33 25.25 4 5 202 22.2 5.11 HVO_1048 phosphoribosylformylglycinamidine synthase 2 25.21 1 12 12 56 1.260E9 66.57 24.22 11 25 4607.40 25.21 12 31 702 72.9 4.18 HVO_B0371 aldehyde dehydrogenase 25.20 1 6 6 22 2.330E8 11.25 20.16 5 9 1019.12 25.20 6 13 496 52.5 4.39 >sp|TRYP_PIG| 25.11 1 4 4 133 4.878E10 149.83 25.11 4 68 10213.66 25.11 4 65 231 24.4 7.18 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 25.08 1 6 6 30 2.184E8 19.68 25.08 6 15 1639.07 25.08 6 15 327 36.2 4.63 HVO_0100 NMD3 family protein 25.07 1 6 6 20 1.820E8 18.12 25.07 6 10 1272.77 22.67 5 10 375 41.6 4.46 HVO_A0288 probable oxidoreductase (short-chain dehydrogenase family) 25.00 1 5 5 20 8.719E7 21.87 25.00 5 10 1471.42 25.00 5 10 280 29.9 4.74 HVO_0123 signal recognition particle 54K protein 24.95 1 10 10 43 5.043E8 39.97 22.80 9 20 3097.18 24.95 10 23 465 50.9 4.50 HVO_0916 diphthine synthase 24.91 1 5 5 16 8.384E8 15.14 24.91 5 8 1021.37 24.91 5 8 269 29.1 4.54 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 24.87 1 4 4 19 2.520E8 8.68 17.99 3 9 1204.43 24.87 4 10 189 21.7 4.46 HVO_0768 radical SAM domain protein 24.78 1 7 7 16 1.101E8 7.20 24.78 7 8 413.62 24.78 7 8 565 62.0 4.84 HVO_0551 DNA mismatch repair protein MutL 24.76 1 12 12 51 3.026E8 43.01 24.76 12 26 3234.72 24.76 12 25 735 78.7 4.50 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 24.72 1 5 6 22 2.170E8 23.96 24.72 6 11 1539.64 24.72 6 11 267 28.8 4.55 HVO_1510 2-isopropylmalate synthase 24.55 1 7 7 29 1.316E9 24.57 24.55 7 14 1885.78 24.55 7 15 440 47.7 4.82 HVO_0469 AstE family protein 24.53 1 6 6 21 3.094E8 22.23 24.53 6 10 1323.32 24.53 6 11 318 33.9 5.85 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 24.53 1 5 5 21 3.463E8 20.18 24.53 5 10 1623.37 24.53 5 11 265 29.3 4.92 HVO_1957 proteasome-activating nucleotidase 24.51 1 6 8 21 1.785E8 12.62 22.82 7 10 979.91 24.51 8 11 412 45.6 4.48 HVO_0795 transcription initiation factor TFB 24.48 1 7 7 25 2.847E8 19.24 24.48 7 13 1074.25 24.48 7 12 335 37.4 5.59 HVO_1866 uridylate kinase 24.47 1 4 4 21 7.359E8 25.62 24.47 4 10 1709.27 24.47 4 11 237 24.6 4.42 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 24.40 1 10 10 37 2.470E8 24.14 24.40 10 19 1931.83 24.40 10 18 586 63.4 4.70 HVO_2266 hypothetical protein 24.34 1 9 9 38 4.934E8 27.24 24.34 9 19 2190.34 24.34 9 19 493 56.7 4.54 HVO_2250 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 24.31 1 3 3 10 1.116E8 5.56 24.31 3 5 369.36 24.31 3 5 181 19.5 4.28 HVO_1340 "probable glycosyltransferase, type 1" 24.27 1 7 7 24 4.886E8 10.07 24.27 7 12 1583.64 24.27 7 12 375 41.0 4.42 HVO_2564 50S ribosomal protein L3 24.26 1 6 6 17 1.134E8 10.15 24.26 6 9 935.32 20.71 5 8 338 37.2 6.68 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 24.13 1 10 10 39 3.152E8 39.25 24.13 10 20 2855.16 24.13 10 19 634 66.1 4.54 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 24.02 1 8 8 25 3.384E8 22.41 19.32 6 11 1330.70 24.02 8 14 383 42.0 4.49 HVO_0220 ATP-dependent DNA helicase MCM 23.93 1 13 13 35 1.944E8 23.89 22.79 12 16 1872.29 23.93 13 19 702 78.8 4.73 HVO_1527 glucose-1-phosphate uridylyltransferase 23.87 1 7 7 34 7.851E8 28.96 23.46 6 17 2094.86 23.87 7 17 243 27.5 4.70 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 23.84 1 6 6 17 2.298E8 6.84 23.84 6 8 800.63 23.84 6 9 323 34.9 5.24 HVO_1187 conserved hypothetical protein 23.78 1 3 3 5 6.264E7 1.68 13.99 2 2 136.32 23.78 3 3 143 16.4 4.86 HVO_1550 acyl-CoA thioester hydrolase 23.75 1 3 3 10 3.774E8 8.34 16.88 2 4 780.83 23.75 3 6 160 17.6 4.55 HVO_0120 signal recognition particle receptor FtsY 23.68 1 7 7 21 2.819E8 20.05 15.79 6 10 1279.41 23.68 7 11 456 48.2 4.17 HVO_0304 electron transfer flavoprotein alpha subunit 23.66 1 4 4 21 4.787E8 12.37 20.50 3 9 1252.38 23.66 4 12 317 33.5 4.18 HVO_B0040 IclR family transcription regulator 23.51 1 5 5 18 5.186E7 4.64 23.51 5 9 562.63 23.51 5 9 251 27.2 5.30 HVO_0893 methylmalonyl-CoA mutase subunit A 23.50 1 10 10 44 7.110E8 42.35 23.50 10 22 2845.85 23.50 10 22 566 63.1 4.36 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 23.48 1 6 6 20 1.251E8 8.55 19.21 5 9 884.04 23.48 6 11 328 36.1 4.67 HVO_1087 UspA domain protein 23.40 1 3 3 7 1.038E8 6.99 23.40 3 4 402.45 8.51 2 3 141 15.2 4.98 HVO_1337 rpa-associated protein 23.27 1 9 9 33 9.540E8 27.40 23.27 9 16 2031.57 23.27 9 17 623 64.8 3.68 HVO_1453 glutamate dehydrogenase (NADP) 23.26 1 8 8 27 7.195E8 18.43 23.26 8 14 1367.90 23.26 8 13 417 45.7 4.49 HVO_1287 PfpI family protease 23.23 1 3 3 10 2.536E8 7.39 23.23 3 5 457.99 23.23 3 5 198 21.5 4.53 HVO_1579 uridine phosphorylase 23.16 1 4 4 12 1.823E8 13.43 23.16 4 6 672.57 23.16 4 6 272 29.0 4.64 HVO_3014 origin-associated GTP-binding protein OapA 23.00 1 4 4 12 2.037E8 6.56 19.72 3 5 580.51 23.00 4 7 213 24.0 5.01 HVO_1567 conserved hypothetical protein 22.98 1 4 4 17 5.387E8 16.12 22.98 4 8 1012.15 22.98 4 9 235 25.7 4.36 HVO_0970 ribulose-bisphosphate carboxylase large subunit 22.95 1 8 8 62 6.590E8 49.15 22.95 8 31 4002.42 22.95 8 31 414 43.9 4.59 HVO_B0143 receiver/sensor box histidine kinase 22.95 1 11 11 41 4.523E8 36.88 22.95 11 21 2662.27 22.95 11 20 597 66.0 4.41 HVO_1179 homolog to NAD kinase 22.88 1 5 5 16 8.239E7 8.01 22.88 5 8 602.13 22.88 5 8 354 36.7 4.60 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 22.83 1 3 3 8 9.336E7 6.45 22.83 3 4 434.65 22.83 3 4 219 22.4 4.06 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 22.83 1 6 6 16 1.621E8 12.84 21.00 5 7 1259.55 22.83 6 9 438 46.4 4.58 HVO_1783 conserved hypothetical protein 22.77 1 3 3 8 8.239E7 5.02 22.77 3 4 360.79 22.77 3 4 224 24.1 5.90 HVO_2784 30S ribosomal protein S13 22.75 1 3 3 9 1.672E8 6.66 22.75 3 5 539.37 22.75 3 4 167 18.9 5.17 HVO_0826 peptidase M42 family protein 22.70 1 5 5 21 1.113E8 14.93 22.70 5 10 1074.33 22.70 5 11 348 37.7 4.54 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 22.69 1 7 7 60 3.719E9 69.34 22.69 7 30 4116.74 22.69 7 30 357 40.3 4.40 HVO_2313 siroheme decarboxylase AhbB 22.66 1 5 5 21 4.932E8 17.40 19.83 4 10 1329.74 22.66 5 11 353 39.6 4.64 HVO_0354 30S ribosomal protein S7 22.55 1 4 4 14 4.607E8 13.15 22.55 4 7 923.40 22.55 4 7 204 22.6 5.14 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 22.53 1 7 7 28 2.028E8 24.76 22.53 7 14 1715.37 22.53 7 14 475 49.3 4.49 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 22.52 1 13 13 56 3.673E8 54.26 20.11 12 27 3717.90 22.52 13 29 706 73.3 4.39 HVO_0745 "FtsZ family protein, type III" 22.50 1 4 4 14 1.695E8 7.38 22.50 4 8 859.62 13.89 3 6 360 37.1 4.51 HVO_2662 homolog to lactoylglutathione lyase 22.49 1 5 5 20 1.654E8 17.71 22.49 5 10 1383.46 22.49 5 10 329 36.5 4.48 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 22.33 1 7 7 30 4.519E8 25.08 22.33 7 15 2023.53 22.33 7 15 430 45.1 4.50 HVO_1500 1-phosphofructokinase 22.30 1 4 4 16 2.233E8 11.09 22.30 4 8 733.95 22.30 4 8 305 32.0 4.51 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 22.22 1 4 4 15 3.264E8 18.44 12.65 3 7 1325.50 22.22 4 8 324 33.6 3.99 HVO_1989 tRNA (pseudouridine(54)-N(1))-methyltransferase 22.22 1 2 2 6 1.258E8 4.97 22.22 2 3 280.44 22.22 2 3 198 21.9 4.79 HVO_2793 conserved hypothetical protein 22.22 1 4 4 14 1.662E8 10.41 22.22 4 7 766.62 22.22 4 7 252 27.1 4.46 HVO_2347 conserved hypothetical protein 22.14 1 2 2 6 9.674E7 4.44 22.14 2 3 400.52 22.14 2 3 140 15.5 4.37 HVO_1374 acyl-CoA synthetase 22.06 1 10 10 37 9.246E8 35.01 19.53 9 18 2392.78 22.06 10 19 553 61.1 4.50 HVO_0876 methylglyoxal synthase 22.05 1 2 2 4 7.578E8 4.86 22.05 2 4 127 13.9 4.48 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 21.94 1 3 3 11 1.455E8 2.10 10.55 2 5 280.37 21.94 3 6 237 26.2 4.70 HVO_0853 DNA double-strand break repair protein Mre11 21.77 1 9 9 31 2.147E8 18.93 21.32 8 15 1586.73 21.77 9 16 441 48.1 4.39 HVO_A0133 conserved hypothetical protein 21.58 1 6 6 28 4.480E8 22.84 19.86 5 13 1909.56 21.58 6 15 292 30.8 5.17 HVO_A0551 acyl-CoA synthetase 21.56 1 10 10 38 5.540E8 42.17 21.56 10 19 2601.51 21.56 10 19 538 59.6 4.65 HVO_0639 AAA-type ATPase (MoxR subfamily) 21.52 1 6 6 29 1.523E8 21.46 21.52 6 15 1692.99 21.52 6 14 316 34.7 4.89 HVO_1380 methylmalonyl-CoA mutase subunit A 21.51 1 8 8 36 1.931E8 35.55 21.51 8 18 2279.58 21.51 8 18 558 61.9 4.41 HVO_2707 GFO family oxidoreductase 21.51 1 6 7 29 1.209E9 33.17 19.62 6 14 2127.20 21.51 7 15 372 41.0 4.55 HVO_B0057 precorrin-3B C17-methyltransferase 21.51 1 4 4 20 5.402E8 18.92 21.51 4 10 1144.31 21.51 4 10 344 36.3 4.31 HVO_1375 O-succinylbenzoic acid--CoA ligase 21.50 1 9 9 27 2.545E8 27.03 18.08 8 13 1816.85 21.50 9 14 614 64.7 4.28 HVO_A0476 conserved hypothetical protein 21.45 1 5 5 14 8.015E7 4.83 21.45 5 7 665.18 21.45 5 7 331 35.4 4.26 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 21.43 1 10 10 33 2.784E8 23.40 11.55 6 14 2016.94 21.43 10 19 658 72.1 4.70 HVO_0054 glycine--tRNA ligase 21.38 1 8 8 30 2.335E9 24.46 19.02 7 14 2432.72 21.38 8 16 594 64.9 4.21 HVO_0937 FMN-binding domain protein 21.23 1 2 2 8 1.100E8 9.75 21.23 2 4 565.29 21.23 2 4 146 16.2 4.36 HVO_1446 "fructose-1,6-bisphosphatase" 21.21 1 4 4 14 1.357E8 13.69 17.17 3 6 983.94 21.21 4 8 297 31.6 4.45 HVO_1885 TrkA domain protein 21.20 1 2 2 6 1.572E8 2.60 21.20 2 3 202.57 21.20 2 3 217 23.4 4.75 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 21.12 1 8 8 25 4.348E8 13.89 18.97 7 12 1206.07 21.12 8 13 464 53.1 4.54 HVO_1268 conserved hypothetical protein 21.10 1 3 3 12 9.424E7 12.06 21.10 3 6 912.94 21.10 3 6 237 26.4 5.21 HVO_2168 AAA-type ATPase (MoxR subfamily) 20.97 1 6 6 22 3.202E8 21.52 20.97 6 11 1312.50 20.97 6 11 329 35.9 4.54 HVO_0741 DNA-directed DNA polymerase X 20.96 1 6 6 25 1.034E8 19.68 20.96 6 13 1109.35 14.95 5 12 582 62.6 4.44 HVO_2108 IclR family transcription regulator 20.95 1 4 4 12 8.390E7 4.34 20.95 4 6 430.20 20.95 4 6 253 28.0 5.74 HVO_1371 glutamate 5-kinase 20.93 1 5 5 22 4.557E8 26.41 20.93 5 11 2034.83 20.93 5 11 301 32.0 4.25 HVO_0001 Orc1-type DNA replication protein 20.92 1 9 9 27 9.994E7 27.93 20.92 9 14 1580.66 20.92 9 13 564 62.1 4.39 HVO_2029 Lrp/AsnC family transcription regulator 20.92 1 1 2 9 5.818E8 6.43 20.92 2 4 451.83 20.92 2 5 153 16.9 4.21 HVO_1373 acyl-CoA dehydrogenase 20.89 1 4 4 11 4.225E8 10.15 12.01 3 5 731.14 20.89 4 6 383 42.5 4.61 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 20.88 1 2 2 7 4.226E7 4.74 20.88 2 3 360.51 20.88 2 4 91 10.4 4.07 HVO_0233 ribose-phosphate pyrophosphokinase 20.85 1 4 4 25 2.838E8 20.33 20.85 4 13 1546.65 20.85 4 12 283 29.6 4.40 HVO_1711 glucoamylase 20.85 1 24 24 79 5.432E8 63.33 18.46 22 38 4836.30 20.85 24 41 1511 166.1 4.64 HVO_B0130 DUF296 family protein 20.74 1 2 2 6 3.704E8 1.92 20.74 2 3 316.38 20.74 2 3 135 14.8 4.41 HVO_0854 DNA double-strand break repair ATPase Rad50 20.72 1 16 16 49 3.951E8 44.54 19.93 15 24 3135.17 20.72 16 25 893 100.0 4.58 HVO_2761 mevalonate kinase 20.71 1 5 5 14 1.354E8 16.95 13.62 4 6 941.21 20.71 5 8 367 38.2 4.31 HVO_B0324 conserved hypothetical protein 20.71 1 7 7 20 1.780E8 11.53 12.92 5 9 1119.66 20.71 7 11 449 48.0 4.58 HVO_1710 alpha amylase 20.68 1 11 11 32 3.122E8 22.99 13.00 9 15 2120.29 19.35 10 17 677 75.0 4.45 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 20.59 1 7 7 24 5.010E8 16.66 20.59 7 12 1234.95 20.59 7 12 612 67.3 4.16 HVO_B0115 fumarylacetoacetase family protein 20.49 1 4 4 18 6.048E8 13.78 20.49 4 9 1113.17 20.49 4 9 283 30.3 4.21 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 20.45 1 23 24 76 3.637E8 34.13 20.45 24 39 3349.63 17.23 21 37 1335 150.5 4.60 HVO_A0150 TrmB family transcription regulator 20.34 1 6 6 25 3.635E8 16.37 17.23 5 12 1381.04 20.34 6 13 354 39.0 4.63 HVO_A0307 Lrp/AsnC family transcription regulator 20.34 1 3 3 9 1.721E8 8.99 14.12 2 4 661.60 20.34 3 5 177 19.4 4.39 HVO_0580 putative tRNA 2-thiolation protein 20.25 1 5 5 9 7.271E7 4.90 20.25 5 5 289.64 17.76 4 4 321 36.1 5.01 HVO_0014 ATP-dependent DNA helicase Hel308a 20.07 1 14 14 50 3.227E8 35.52 20.07 14 25 2942.93 17.41 13 25 827 90.3 4.67 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 20.06 1 6 6 19 1.981E8 13.80 15.12 4 8 1346.07 20.06 6 11 344 37.0 4.55 HVO_0402 DUF124 family protein 20.00 1 3 3 10 6.361E8 6.84 20.00 3 5 550.99 20.00 3 5 225 24.0 4.58 HVO_A0586 sugar nucleotidyltransferase 19.95 1 6 6 22 2.304E8 9.94 19.95 6 11 1286.07 19.95 6 11 411 43.7 4.69 HVO_1723 DNA repair helicase Rad25 19.86 1 11 11 31 1.233E8 27.27 18.99 10 15 1861.91 18.99 10 16 695 76.8 4.69 HVO_1139 squalene synthase 19.83 1 5 5 18 2.765E8 14.11 19.83 5 9 1094.78 19.83 5 9 358 39.7 4.54 HVO_2779 50S ribosomal protein L18e 19.83 1 2 2 10 4.644E7 10.84 19.83 2 5 698.94 19.83 2 5 116 12.7 8.50 HVO_0979 NADH dehydrogenase-like complex subunit B 19.74 1 4 4 10 1.913E8 1.73 19.74 4 5 363.25 19.74 4 5 233 26.1 5.01 HVO_1323 "shikimate kinase, archaeal-type" 19.72 1 4 4 20 3.989E8 15.71 19.72 4 10 1475.16 19.72 4 10 289 29.5 4.30 HVO_0048 argininosuccinate lyase 19.67 1 6 6 30 2.475E8 32.46 19.67 6 15 2323.96 19.67 6 15 488 50.8 4.53 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 19.57 1 2 2 6 1.216E8 4.44 19.57 2 3 294.01 19.57 2 3 184 20.0 4.75 HVO_1878 NAD synthase 19.57 1 5 5 20 2.753E8 11.65 19.57 5 10 978.43 19.57 5 10 276 29.6 4.37 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 19.49 1 1 10 36 9.684E8 34.32 19.49 10 18 2272.68 19.49 10 18 472 51.6 5.16 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 19.46 1 13 13 43 1.670E8 25.36 19.46 13 20 2590.10 19.46 13 23 740 85.6 4.70 HVO_A0452 UspA domain protein 19.45 1 4 4 11 8.042E7 4.97 19.45 4 5 499.46 19.45 4 6 293 31.3 4.63 HVO_A0087 fumarylacetoacetase family protein 19.38 1 5 5 17 3.632E8 13.69 19.38 5 9 931.02 19.38 5 8 289 32.0 4.21 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 22 2.122E9 20.57 19.31 5 11 1615.35 16.67 4 11 378 39.7 4.67 HVO_1496 phosphotransferase system component I 19.29 1 10 10 39 5.451E8 33.18 19.29 10 20 2601.58 19.29 10 19 565 60.3 4.21 HVO_0056 conserved hypothetical protein 19.27 1 3 3 6 5.822E7 1.91 12.50 2 3 185.85 14.58 2 3 192 20.9 4.16 HVO_0234 conserved hypothetical protein 19.27 1 3 3 8 1.063E8 2.49 19.27 3 4 223.47 19.27 3 4 275 28.1 4.48 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 19.27 1 6 6 18 9.946E7 6.61 19.27 6 9 703.88 12.93 5 9 410 46.0 4.89 HVO_2636 PspA domain protein 19.20 1 5 5 16 5.252E7 16.56 16.67 4 8 1317.82 19.20 5 8 276 30.9 4.61 HVO_C0077 sarcosine oxidase 19.12 1 4 4 13 1.795E8 14.75 19.12 4 6 999.77 19.12 4 7 387 42.9 4.70 HVO_2581 quinolinate synthase A 18.96 1 6 6 32 4.143E8 25.57 18.96 6 16 1884.28 18.96 6 16 385 42.0 4.41 HVO_0712 shikimate dehydrogenase (nonfunctional) 18.96 1 3 3 7 1.153E8 3.47 18.96 3 4 215.06 18.96 3 3 269 27.7 4.65 HVO_0034 acyl-CoA thioester hydrolase 18.90 1 2 2 8 1.993E8 3.86 18.90 2 4 429.03 18.90 2 4 164 18.3 4.65 HVO_0143 PhzF family protein 18.84 1 2 2 2 2.086E7 29.27 18.84 2 2 292 31.8 4.40 HVO_0697 PAC2 family protein 18.82 1 2 2 14 6.466E8 17.21 18.82 2 7 1366.91 18.82 2 7 255 27.4 4.08 HVO_1501 DeoR family transcription regulator GlpR 18.82 1 4 4 17 1.385E8 12.82 18.82 4 8 905.02 18.82 4 9 255 28.0 4.97 HVO_B0200 malate synthase 18.81 1 4 4 14 4.838E8 20.15 18.81 4 7 1077.88 18.81 4 7 436 48.3 4.30 HVO_2001 tRNA-guanine(15) transglycosylase 18.80 1 5 5 18 3.082E8 22.74 18.80 5 9 1409.91 15.31 4 9 516 56.3 4.59 HVO_0818 threonine synthase 18.77 1 6 6 30 5.008E8 25.30 18.77 6 15 1905.14 18.77 6 15 389 40.8 4.31 HVO_A0002 conserved hypothetical protein 18.75 1 2 2 6 6.288E7 10.53 18.75 2 3 723.90 18.75 2 3 192 20.7 4.02 HVO_2547 50S ribosomal protein L32e 18.72 1 3 3 14 1.253E8 17.31 18.72 3 7 1063.10 18.72 3 7 235 25.8 4.75 HVO_1407 HTH domain protein 18.67 1 3 3 13 9.437E7 7.34 18.67 3 7 654.14 18.67 3 6 225 24.9 4.45 HVO_0087 porphobilinogen synthase 18.65 1 6 6 27 4.044E8 26.97 18.65 6 13 1846.36 18.65 6 14 327 35.3 4.72 HVO_2945 valine--tRNA ligase 18.62 1 15 15 71 1.378E9 82.12 16.21 12 33 5730.02 18.62 15 38 870 98.9 4.36 HVO_A0465 TetR family transcription regulator 18.57 1 3 3 9 1.357E8 6.88 18.57 3 4 546.77 18.57 3 5 210 23.7 4.48 HVO_2763 homolog to ribonuclease Z 18.55 1 4 4 18 3.031E8 13.68 18.55 4 9 1065.10 18.55 4 9 248 26.6 4.53 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 20 4.659E8 19.97 18.29 4 10 1236.40 18.29 4 10 257 26.8 4.01 HVO_1177 CinA N-terminal domain protein 18.26 1 2 2 7 1.914E8 2.48 18.26 2 3 307.85 18.26 2 4 230 24.5 4.36 HVO_0484 50S ribosomal protein L10e 18.18 1 2 2 8 2.315E8 7.59 18.18 2 4 581.05 18.18 2 4 176 19.8 8.72 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 18.18 1 4 4 16 2.446E8 9.82 18.18 4 8 836.25 18.18 4 8 286 30.8 4.46 HVO_1683 4-alpha-glucanotransferase 18.15 1 7 7 23 2.692E8 17.17 16.13 6 11 1281.28 18.15 7 12 496 56.3 4.45 HVO_0699 translation initiation factor aIF-2 alpha subunit 18.05 1 5 5 30 6.241E8 25.16 18.05 5 15 1744.00 18.05 5 15 266 29.5 4.46 HVO_3000 DNA ligase (NAD) 18.03 1 8 8 36 8.315E8 17.45 18.03 8 19 1633.47 14.88 7 17 699 75.8 4.50 HVO_1803 conserved hypothetical protein 18.00 1 3 3 7 6.579E7 7.46 18.00 3 4 321.75 12.50 2 3 200 21.7 5.07 HVO_0429 archaemetzincin 17.92 1 2 2 8 2.000E8 4.17 17.92 2 4 454.43 17.92 2 4 173 19.3 6.54 HVO_0824 "probable glycosyltransferase, type 1" 17.90 1 5 5 12 1.169E8 8.04 17.90 5 6 562.47 17.90 5 6 352 39.6 5.08 HVO_1559 HTH/CBS domain protein 17.88 1 2 2 2 4.297E7 1.60 17.88 2 2 179 19.5 4.48 HVO_0414 peptidase M24 family protein 17.80 1 3 3 10 1.096E8 2.11 17.80 3 4 310.86 17.80 3 6 382 39.4 4.82 HVO_0441 probable metallo-beta-lactamase family hydrolase 17.79 1 2 2 6 8.702E7 4.77 17.79 2 3 261.78 17.79 2 3 208 22.7 4.51 HVO_1295 histidinol-phosphate aminotransferase 17.73 1 4 4 21 3.820E8 18.58 17.73 4 10 1428.45 17.73 4 11 361 39.4 4.51 HVO_B0052 PQQ repeat protein 17.72 1 6 6 14 1.283E8 7.11 17.72 6 7 815.48 17.72 6 7 412 44.1 5.48 HVO_0017 conserved hypothetical protein 17.71 1 3 3 10 3.448E8 7.81 14.06 2 4 690.10 17.71 3 6 192 21.9 4.50 HVO_1129 conserved hypothetical protein 17.69 1 4 5 20 3.713E8 22.15 17.69 5 10 1229.98 17.69 5 10 390 43.0 4.44 HVO_1823 UspA domain protein 17.65 1 2 2 6 2.249E7 6.49 17.65 2 3 391.54 17.65 2 3 153 16.4 4.60 HVO_1098 diaminopimelate decarboxylase 17.59 1 7 7 26 4.019E8 12.09 17.59 7 13 1012.75 17.59 7 13 415 44.4 5.02 HVO_2350 YyaL family protein 17.57 1 6 6 17 1.471E8 7.56 17.57 6 8 747.80 17.57 6 9 552 58.8 4.59 HVO_A0635 probable cysteine desulfurase 17.52 1 4 4 9 3.648E8 8.73 15.09 3 4 460.15 17.52 4 5 371 40.4 4.53 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 17.49 1 4 4 16 1.771E8 26.36 17.49 4 8 1600.03 17.49 4 8 446 47.9 4.39 HVO_A0439 DUF2800 family protein 17.48 1 3 4 12 4.735E7 7.54 17.48 4 6 582.26 17.48 4 6 326 36.9 4.51 HVO_2383 DNA repair and recombination protein RadB 17.47 1 3 3 12 1.852E8 9.02 17.47 3 6 699.63 17.47 3 6 229 24.6 5.02 HVO_0179 Lrp/AsnC family transcription regulator / TrkA domain protein 17.24 1 3 3 11 1.774E8 8.42 17.24 3 6 600.83 17.24 3 5 261 28.0 4.58 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 17.23 1 3 4 12 2.075E8 12.59 17.23 4 6 928.11 17.23 4 6 383 41.9 4.21 HVO_1656 YyaL family protein 17.21 1 11 11 50 1.780E8 26.67 17.21 11 25 2584.87 17.21 11 25 703 77.3 4.49 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 17.12 1 6 6 28 1.593E8 27.41 14.89 5 13 1553.61 17.12 6 15 403 41.1 4.73 HVO_1650 polyphosphate kinase 17.07 1 11 11 31 1.249E8 17.86 17.07 11 16 1554.71 17.07 11 15 832 93.6 4.65 HVO_0209 acyl-CoA dehydrogenase 17.05 1 6 6 22 1.147E8 10.94 17.05 6 10 967.47 17.05 6 12 387 42.4 4.93 HVO_B0058 precorrin-3B C17-methyltransferase 17.01 1 3 3 10 6.074E7 5.53 17.01 3 5 494.99 17.01 3 5 294 31.8 4.40 HVO_2227 siroheme decarboxylase AhbA 17.00 1 4 4 12 1.438E8 12.76 17.00 4 6 914.72 17.00 4 6 347 39.1 4.69 HVO_A0328 2-keto-3-deoxygluconate kinase 16.98 1 3 4 18 2.282E8 10.60 16.98 4 9 828.84 16.98 4 9 318 34.0 4.60 HVO_A0305 methylmalonate-semialdehyde dehydrogenase 16.97 1 6 6 20 1.597E8 20.52 16.97 6 10 1245.07 16.97 6 10 489 52.1 4.59 HVO_B0111 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 16.96 1 4 4 15 1.281E8 11.90 16.96 4 8 633.10 16.96 4 7 401 44.2 4.54 HVO_A0486 hydrogenase expression/formation protein 16.96 1 3 3 10 1.003E8 8.38 16.96 3 5 609.59 16.96 3 5 336 33.8 4.06 HVO_1175 DUF2110 family protein 16.89 1 3 3 16 1.465E9 23.08 16.89 3 8 1490.23 16.89 3 8 225 24.4 4.63 HVO_1419 HTH-10 family transcription regulator 16.89 1 2 2 4 2.130E7 0.00 16.89 2 2 123.86 16.89 2 2 225 25.2 4.77 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 16.67 1 0 7 46 3.850E8 34.72 16.67 7 23 2960.27 16.67 7 23 384 42.4 5.40 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 16.67 1 6 6 21 1.282E8 15.78 16.67 6 11 1160.76 16.67 6 10 420 45.0 4.86 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 16.54 1 5 5 13 1.607E8 4.56 11.55 4 6 569.33 16.54 5 7 381 40.5 4.51 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 16.49 1 2 2 8 2.127E8 5.94 16.49 2 4 301.33 16.49 2 4 97 10.8 4.53 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 16.47 1 0 2 8 1.124E9 5.29 16.47 2 4 435.11 16.47 2 4 85 10.0 5.94 HVO_2923 proteasome alpha subunit 16.47 1 3 4 21 4.869E8 9.24 16.47 4 10 1022.40 16.47 4 11 249 26.7 4.39 HVO_0868 NAD-dependent epimerase/dehydratase 16.41 1 5 5 16 1.218E8 6.93 12.46 4 7 813.72 16.41 5 9 329 36.1 4.55 HVO_B0183 YgeA family protein 16.33 1 4 4 12 3.159E8 7.54 16.33 4 6 543.72 16.33 4 6 245 26.8 4.58 HVO_2072 S-layer glycoprotein 16.32 1 6 6 45 2.176E9 30.54 16.32 6 24 1703.87 11.49 5 21 827 85.1 3.65 HVO_0180 23S rRNA (uridine-2'-O-) methyltransferase 16.22 1 3 3 6 6.276E7 5.20 16.22 3 3 263.47 16.22 3 3 259 28.3 4.70 HVO_2600 methionyl aminopeptidase 16.22 1 6 6 18 2.964E8 13.15 12.16 5 8 1142.18 16.22 6 10 296 32.3 4.41 HVO_0326 CTP-dependent riboflavin kinase 16.03 1 3 3 9 1.191E8 9.44 12.24 2 4 705.73 16.03 3 5 237 25.9 4.55 HVO_2060 NUDIX family hydrolase 16.03 1 2 2 6 2.776E8 0.00 16.03 2 3 163.87 16.03 2 3 156 17.7 4.41 HVO_A0257 Orc1-type DNA replication protein 16.00 1 7 8 21 1.046E8 11.43 16.00 7 10 1120.66 13.18 7 11 425 48.0 4.94 HVO_1725 Orc1-type DNA replication protein 15.96 1 6 6 23 1.433E8 12.22 13.47 5 11 1280.62 15.96 6 12 401 44.5 5.19 HVO_1895 KEOPS complex subunit Kae1/Bud32 15.94 1 6 6 19 1.575E8 22.05 15.94 6 10 1237.64 14.31 5 9 552 59.0 5.07 HVO_B0060 precorrin-4 C11-methyltransferase 15.77 1 3 3 18 2.686E8 10.55 15.77 3 9 763.90 15.77 3 9 279 29.7 4.22 HVO_B0182 deoxyhypusine synthase 15.74 1 4 4 14 1.033E8 10.45 15.74 4 7 906.68 15.74 4 7 324 35.6 4.30 HVO_0475 conserved hypothetical protein 15.71 1 3 3 10 4.645E7 5.97 15.71 3 5 321.55 15.71 3 5 312 32.5 4.74 HVO_2456 anthranilate phosphoribosyltransferase 15.71 1 3 3 10 3.882E8 4.88 15.71 3 5 387.58 15.71 3 5 331 33.8 4.35 HVO_2914 conserved hypothetical protein 15.71 1 2 2 4 6.340E7 0.00 15.71 2 2 94.77 15.71 2 2 140 16.1 4.61 HVO_1979 tRNA pseudouridine synthase Pus10 15.69 1 6 6 27 8.946E8 26.77 15.69 6 14 1739.02 15.69 6 13 427 46.9 4.39 HVO_0195 ribose-5-phosphate isomerase 15.65 1 3 3 8 2.136E8 4.20 15.65 3 4 391.90 15.65 3 4 230 23.2 4.54 HVO_1629 conserved hypothetical protein 15.63 1 6 6 20 6.053E8 13.16 15.63 6 10 1011.67 15.63 6 10 531 56.3 4.69 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 15.62 1 5 5 21 2.149E8 11.27 15.62 5 10 827.43 15.62 5 11 365 39.0 4.61 HVO_A0555 DUF162 family protein 15.60 1 2 2 2 4.266E7 0.00 15.60 2 2 218 23.7 4.12 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 15.58 1 5 5 24 4.027E8 22.91 15.58 5 12 1483.98 15.58 5 12 430 44.2 4.37 HVO_0069 sulfatase 15.53 1 6 6 11 1.457E8 3.28 10.87 4 5 615.87 13.98 5 6 515 57.4 4.35 HVO_0760 "probable glycosyltransferase, type 2" 15.49 1 5 5 12 1.193E8 7.30 15.49 5 6 791.33 15.49 5 6 368 40.7 4.82 HVO_1594 tRNA/rRNA cytosine-C5-methylase 15.34 1 4 4 12 1.800E8 11.92 15.34 4 6 708.68 15.34 4 6 313 34.6 4.69 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 15.34 1 5 5 24 3.264E8 17.28 15.34 5 12 1288.02 15.34 5 12 378 39.8 4.45 HVO_1812 conserved hypothetical protein 15.20 1 4 4 16 1.295E8 12.88 15.20 4 8 773.05 15.20 4 8 375 40.5 4.50 HVO_2777 30S ribosomal protein S9 15.15 1 2 2 6 5.017E7 1.70 15.15 2 3 299.50 15.15 2 3 132 14.7 9.74 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 15.15 1 5 5 19 1.594E8 5.38 15.15 5 9 574.18 15.15 5 10 482 50.6 4.31 HVO_1344 SBDS family protein 15.13 1 3 3 11 5.672E7 6.95 15.13 3 6 470.77 15.13 3 5 238 26.5 4.51 HVO_0733 transcription initiation factor TFB 15.03 1 1 5 18 1.033E9 17.27 15.03 5 9 1247.27 15.03 5 9 326 37.2 6.00 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 15.02 1 4 4 14 9.610E7 9.77 15.02 4 7 823.17 15.02 4 7 406 43.1 4.60 HVO_2530 homolog to phosphoribosylamine--glycine ligase 15.00 1 4 4 11 8.209E7 5.87 15.00 4 6 568.35 8.18 3 5 440 49.8 4.70 HVO_1250 redoxin domain protein 14.97 1 2 2 4 1.627E8 786.70 14.97 2 4 187 20.5 4.03 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 14.80 1 7 7 31 2.221E8 26.75 14.80 7 14 1748.33 14.80 7 17 838 89.1 4.65 HVO_1681 DNA N-glycosylase 14.80 1 3 3 10 4.023E7 9.63 14.80 3 5 751.89 14.80 3 5 304 34.2 4.63 HVO_0029 UvrABC system protein B 14.76 1 8 8 23 1.266E8 20.74 13.47 7 11 1410.00 14.76 8 12 698 79.0 4.45 HVO_1008 GFO family oxidoreductase 14.76 1 3 3 8 8.036E7 3.50 14.76 3 4 332.07 14.76 3 4 332 36.0 4.72 HVO_0670 glutathione S-transferase 14.72 1 4 4 16 1.537E8 13.44 14.72 4 8 895.68 14.72 4 8 326 38.1 4.56 HVO_1452 citryl-CoA lyase (citrate lyase beta subunit / ATP citrate synthase beta subunit) 14.70 1 2 2 8 5.342E7 7.41 14.70 2 4 438.27 14.70 2 4 279 29.0 4.54 HVO_1918 probable metallo-beta-lactamase family hydrolase 14.57 1 2 2 8 1.580E8 6.11 14.57 2 4 380.62 14.57 2 4 302 34.0 4.55 HVO_1424 conserved hypothetical protein 14.48 1 4 4 12 1.229E8 3.28 14.48 4 6 438.90 14.48 4 6 359 40.9 4.60 HVO_1357 receiver/bat box HTH-10 family transcription regulator 14.43 1 4 4 11 1.520E8 7.18 14.43 4 5 610.43 14.43 4 6 582 62.7 4.40 HVO_B0026 probable oxidoreductase (short-chain dehydrogenase family) 14.40 1 2 2 8 1.317E8 5.02 14.40 2 4 346.14 14.40 2 4 257 26.7 4.55 21961227 Keratin 6B [Homo sapiens] 14.36 1 0 9 60 4.773E8 48.29 14.36 9 30 3817.08 14.36 9 30 564 60.0 8.00 HVO_1413 probable NADH dehydrogenase 14.32 1 4 4 14 2.452E8 13.70 14.32 4 7 958.48 14.32 4 7 377 39.7 4.67 HVO_2479 2-phospho-L-lactate transferase 14.24 1 4 4 13 6.998E7 6.75 10.61 3 6 835.67 14.24 4 7 330 34.7 4.32 HVO_2702 alpha/beta hydrolase fold protein 14.23 1 3 3 15 2.163E8 4.61 14.23 3 8 525.83 14.23 3 7 260 28.0 4.53 HVO_1809 isochorismatase family protein 14.21 1 2 2 6 9.798E7 2.69 14.21 2 3 252.55 14.21 2 3 190 21.0 4.55 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 14.20 1 4 4 16 1.592E8 14.68 14.20 4 8 887.07 14.20 4 8 345 36.9 4.68 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 14.18 1 3 3 12 9.084E7 10.21 14.18 3 6 775.52 14.18 3 6 268 27.9 4.87 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 14.16 1 1 8 30 9.684E8 25.73 14.16 8 15 1832.67 14.16 8 15 473 51.2 5.05 HVO_0464 threonine ammonia-lyase 14.14 1 5 5 13 9.562E7 4.81 14.14 5 7 480.99 9.43 3 6 403 43.7 4.72 HVO_A0228 5'-nucleotidase SurE 14.09 1 2 2 8 1.148E8 7.66 14.09 2 4 464.19 14.09 2 4 291 31.5 4.59 HVO_2639 DUF1611 family protein 14.08 1 2 2 8 1.529E8 8.07 14.08 2 4 498.74 14.08 2 4 341 36.3 4.44 HVO_0990 DHH family phosphoesterase 13.99 1 5 5 20 1.664E8 14.93 13.99 5 10 1076.18 13.99 5 10 486 51.9 4.59 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 13.99 1 4 4 13 8.417E7 9.93 13.99 4 7 658.16 13.99 4 6 386 41.3 4.46 HVO_1058 TrkA domain protein 13.93 1 6 6 23 3.250E8 12.97 13.93 6 12 1033.18 12.13 5 11 445 47.7 4.35 4557890 keratin 5 [Homo sapiens] 13.90 1 0 9 52 4.773E8 34.92 13.90 9 27 3111.66 12.20 8 25 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 13.90 1 0 9 52 4.773E8 34.92 13.90 9 27 3111.66 12.20 8 25 590 62.4 8.06 HVO_1299 HTH domain protein 13.87 1 2 2 3 1.917E8 7.18 13.87 2 3 173 18.9 4.84 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 13.87 1 5 5 19 1.978E8 6.11 13.87 5 10 673.33 13.87 5 9 584 63.3 4.79 HVO_0689 chromosome segregation protein Smc 13.79 1 14 14 46 4.239E8 30.30 13.79 14 24 2453.44 13.39 13 22 1240 138.1 4.39 HVO_1864 molybdopterin synthase catalytic subunit 13.79 1 4 4 7 1.298E8 1.81 13.79 4 4 268.76 10.34 3 3 261 27.9 4.41 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 13.72 1 4 4 17 1.788E8 11.54 13.72 4 8 873.88 13.72 4 9 401 43.1 4.60 HVO_1899 DNA-directed RNA polymerase subunit E 13.68 1 3 3 11 1.116E8 6.61 13.68 3 5 546.60 13.68 3 6 190 21.0 4.74 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 2 1.158E8 144.97 13.66 2 2 183 20.0 4.21 HVO_C0043 conserved hypothetical protein 13.62 1 6 6 18 2.358E8 10.92 13.62 6 9 935.68 13.62 6 9 661 73.8 4.75 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 13.61 1 4 4 20 2.818E8 14.60 13.61 4 10 1032.09 13.61 4 10 360 39.5 4.31 HVO_2873 flap endonuclease Fen1 13.50 1 3 3 9 1.219E8 5.64 6.44 2 4 541.71 13.50 3 5 326 36.4 4.40 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 13.50 1 5 5 20 1.006E8 10.97 13.50 5 10 1167.73 13.50 5 10 437 47.1 4.72 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 13.45 1 2 2 6 3.090E8 4.54 13.45 2 3 285.32 13.45 2 3 238 24.7 4.15 HVO_C0054 hypothetical protein 13.37 1 3 3 7 8.044E7 1.75 13.37 3 4 190.87 10.76 2 3 344 37.5 4.70 HVO_1925 probable GTP-binding protein 13.23 1 4 4 15 1.296E8 3.82 13.23 4 8 574.69 8.92 3 7 325 36.5 4.72 HVO_B0101 IclR family transcription regulator 13.23 1 3 3 10 4.665E7 8.40 13.23 3 5 620.72 13.23 3 5 257 28.6 5.02 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 13.19 1 0 7 28 8.562E8 26.61 13.19 7 14 1651.28 13.19 7 14 432 48.1 5.02 HVO_B0061 precorrin-2 C20-methyltransferase 13.19 1 3 3 12 1.709E8 7.33 13.19 3 6 660.22 13.19 3 6 235 25.3 4.63 HVO_2503 kynureninase 13.18 1 4 4 11 1.552E8 3.02 10.35 3 5 745.50 13.18 4 6 425 46.0 4.54 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 13.16 1 4 4 16 1.303E8 13.10 9.62 3 7 1058.26 13.16 4 9 395 42.4 4.54 HVO_0044 acetylglutamate kinase 13.15 1 3 3 8 2.428E8 8.86 13.15 3 4 599.56 13.15 3 4 327 33.2 4.49 HVO_B0154 receiver/sensor box histidine kinase 13.14 1 12 12 37 2.149E8 22.40 12.07 11 18 1730.82 13.14 12 19 1301 144.1 4.39 HVO_1741 conserved hypothetical protein 13.11 1 3 3 5 2.179E7 1.88 13.11 3 3 168.18 10.06 2 2 328 37.6 4.46 HVO_2871 pyridoxal phosphate-dependent aminotransferase 13.11 1 5 5 19 2.088E8 15.26 10.89 4 9 1197.08 13.11 5 10 450 49.1 4.70 HVO_1150 IS200-type transposase 13.08 1 2 2 7 1.813E8 3.85 13.08 2 4 360.17 13.08 2 3 130 14.7 5.49 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 13.00 1 5 5 17 2.176E8 19.23 11.11 4 8 1214.81 13.00 5 9 423 43.9 4.31 HVO_0600 ACT domain protein 12.99 1 2 2 4 1.153E8 2.28 12.99 2 2 253.91 12.99 2 2 177 19.2 4.44 HVO_0568 TrmB family transcription regulator 12.89 1 4 4 8 8.708E7 2.26 7.16 2 3 261.50 12.89 4 5 349 38.3 4.56 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 12.86 1 3 3 7 8.021E7 2.22 12.86 3 4 290.53 12.86 3 3 280 30.0 4.92 HVO_2363 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 12.82 1 2 2 6 6.255E7 4.16 12.82 2 3 247.57 12.82 2 3 273 27.6 4.40 HVO_1746 DUF2800 family protein 12.69 1 2 3 8 6.323E7 4.16 12.69 3 4 311.81 12.69 3 4 323 36.5 4.37 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 12.67 1 3 3 18 1.191E9 11.10 12.67 3 9 1409.33 12.67 3 9 363 39.7 4.25 HVO_A0498 conserved hypothetical protein 12.66 1 4 4 6 1.205E8 0.00 5.28 2 2 224.91 12.66 4 4 379 42.7 4.55 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 12.59 1 0 8 48 4.773E8 34.72 12.59 8 24 3043.46 12.59 8 24 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 12.59 1 0 8 48 4.773E8 34.72 12.59 8 24 3043.46 12.59 8 24 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 12.59 1 0 8 48 4.773E8 34.72 12.59 8 24 3043.46 12.59 8 24 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 12.59 1 0 8 48 4.773E8 34.72 12.59 8 24 3043.46 12.59 8 24 564 60.0 7.72 HVO_B0233 alpha-L-arabinofuranosidase 12.52 1 5 5 14 1.459E8 14.42 12.52 5 7 1106.61 12.52 5 7 511 57.5 4.39 HVO_2306 receiver box response regulator 12.50 1 2 2 6 1.255E8 1.82 12.50 2 3 160.42 12.50 2 3 248 26.5 4.13 HVO_2955 DEAD/DEAH box helicase 12.45 1 7 7 17 1.592E8 12.34 9.50 6 8 818.20 12.45 7 9 779 85.8 4.94 HVO_0322 MinD/ParA domain protein 12.39 1 4 4 19 4.785E8 19.95 12.39 4 9 1494.25 12.39 4 10 581 58.8 3.70 HVO_1995 conserved hypothetical protein 12.35 1 3 3 8 8.663E7 7.81 12.35 3 4 467.29 12.35 3 4 243 26.5 4.39 HVO_1578 probable NADH dehydrogenase 12.34 1 4 4 12 2.020E8 7.82 12.34 4 7 504.24 6.30 2 5 397 42.8 4.40 HVO_1651 thiamine / thiouridine biosynthesis protein ThiI 12.28 1 3 3 6 2.693E7 2.78 12.28 3 3 373.60 12.28 3 3 391 41.7 4.82 HVO_B0066 Lrp/AsnC family transcription regulator 12.20 1 2 2 8 7.581E7 5.91 12.20 2 4 480.07 12.20 2 4 164 18.5 4.41 HVO_2529 probable oxidoreductase (short-chain dehydrogenase family) 12.17 1 2 2 6 5.527E7 8.23 12.17 2 3 402.12 12.17 2 3 230 23.6 4.72 HVO_2160 conserved hypothetical protein 12.14 1 17 17 148 3.588E9 169.10 12.14 17 74 12058.75 12.14 17 74 2257 232.7 3.92 HVO_B0116 probable oxidoreductase (short-chain dehydrogenase family) 12.08 1 2 2 6 6.614E7 6.20 12.08 2 3 348.44 12.08 2 3 265 28.0 4.53 HVO_2356 GNAT family acetyltransferase 12.04 1 3 3 8 1.295E8 2.56 12.04 3 4 338.95 12.04 3 4 407 45.1 4.64 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 11.97 1 4 4 9 9.269E7 5.00 11.97 4 5 293.46 10.11 3 4 376 41.8 4.91 HVO_1174 transcription initiation factor TFE 11.93 1 2 2 2 5.949E7 198.77 11.93 2 2 176 20.6 4.23 HVO_2229 flavin-containing amine-oxidoreductase 11.92 1 3 3 12 2.092E8 4.00 11.92 3 6 486.04 11.92 3 6 344 37.9 4.92 HVO_0755 NAD-dependent epimerase/dehydratase 11.74 1 2 2 3 7.235E7 4.27 11.74 2 3 298 32.3 4.91 HVO_1311 probable oxidoreductase (short-chain dehydrogenase family) 11.74 1 3 3 10 8.188E7 8.86 11.74 3 5 552.72 11.74 3 5 281 30.1 4.46 HVO_2501 alpha/beta hydrolase fold protein 11.71 1 3 3 8 9.158E7 9.00 11.71 3 5 434.41 9.49 2 3 316 35.3 5.72 HVO_1425 conserved hypothetical protein 11.70 1 3 3 10 8.898E7 2.24 11.70 3 5 384.46 11.70 3 5 265 30.4 4.61 HVO_0547 conserved hypothetical protein 11.68 1 2 2 5 4.526E7 2.49 11.68 2 3 215.88 11.68 2 2 214 24.0 4.39 HVO_A0296 probable oxidoreductase (short-chain dehydrogenase family) 11.55 1 2 2 4 4.757E7 0.00 11.55 2 2 151.20 11.55 2 2 251 26.1 4.72 HVO_A0158 acyl-CoA synthetase 11.54 1 3 6 23 1.654E9 15.75 11.54 6 11 1140.03 11.54 6 12 650 71.2 4.63 HVO_B0031 probable oxidoreductase (short-chain dehydrogenase family) 11.46 1 2 2 2 3.581E7 1.66 11.46 2 2 253 27.0 4.55 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 11.43 1 2 2 6 8.335E7 5.68 11.43 2 3 264.64 11.43 2 3 175 18.8 4.63 HVO_C0044 PLD domain protein 11.41 1 3 3 10 7.856E7 8.00 11.41 3 5 595.21 11.41 3 5 333 36.4 4.94 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 11.39 1 2 2 6 1.879E8 5.00 11.39 2 3 277.59 11.39 2 3 237 25.4 4.46 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 11.37 1 4 4 16 7.466E8 11.75 11.37 4 8 856.86 11.37 4 8 299 32.0 4.53 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 11.35 1 5 5 20 1.877E8 18.34 11.35 5 10 955.88 11.35 5 10 661 71.0 4.35 HVO_A0550 receiver/sensor box histidine kinase 11.30 1 9 9 24 1.107E8 18.66 8.25 7 11 1469.59 11.30 9 13 885 95.9 4.46 HVO_2736 tRNA(Met) cytidine acetyltransferase 11.27 1 7 7 15 1.024E8 9.33 9.28 6 8 583.34 8.75 5 7 754 81.2 4.96 HVO_0207 alpha/beta hydrolase fold protein 11.24 1 3 3 8 4.716E7 5.13 11.24 3 4 322.13 11.24 3 4 258 27.0 4.42 HVO_0454 ornithine cyclodeaminase 11.18 1 3 3 7 1.318E8 2.70 11.18 3 4 242.35 6.95 2 3 331 35.6 4.23 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 11.15 1 3 3 10 1.004E8 13.30 11.15 3 5 798.41 11.15 3 5 574 62.8 4.17 HVO_1565 DNA ligase (ATP) 11.11 1 5 5 16 7.067E7 10.38 11.11 5 8 980.72 11.11 5 8 585 62.7 4.44 HVO_1928 5-formyltetrahydrofolate cyclo-ligase 11.11 1 2 2 8 6.946E7 8.44 11.11 2 4 511.12 11.11 2 4 243 26.5 4.69 HVO_2263 conserved hypothetical protein 11.11 1 7 7 20 1.239E8 10.29 11.11 7 10 882.64 11.11 7 10 801 89.5 5.54 HVO_A0547 DUF1028 family protein 11.11 1 3 3 7 9.863E7 0.00 6.61 2 3 185.44 11.11 3 4 333 35.2 4.16 HVO_A0591 DICT domain protein 11.07 1 2 2 5 4.689E7 2.29 11.07 2 2 210.55 11.07 2 3 253 27.8 4.50 HVO_1537 Orc1-type DNA replication protein 11.00 1 4 4 11 2.901E8 0.00 8.00 3 5 311.18 11.00 4 6 400 42.4 5.52 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 10.94 1 3 3 7 7.249E7 1.73 10.94 3 4 167.37 7.90 2 3 329 36.3 4.49 HVO_A0583 IclR family transcription regulator 10.94 1 3 3 12 5.739E7 11.17 10.94 3 6 696.03 10.94 3 6 256 27.9 5.07 HVO_0569 RIO-type serine/threonine protein kinase 10.89 1 3 3 7 4.838E7 1.86 10.89 3 4 210.27 8.58 2 3 303 34.4 4.94 HVO_1437 conserved hypothetical protein 10.84 1 2 2 6 7.045E7 2.55 10.84 2 3 381.45 10.84 2 3 203 22.3 4.94 386849 keratin type II 10.83 1 0 6 16 4.176E8 13.52 10.83 6 8 1124.19 10.83 6 8 563 59.9 7.94 HVO_1077 diphthamide biosynthesis protein Dph6 10.83 1 2 2 8 1.150E8 8.64 10.83 2 4 477.19 10.83 2 4 240 26.0 4.15 HVO_1615 conserved hypothetical protein 10.76 1 3 3 5 4.694E7 0.00 7.17 2 2 172.93 10.76 3 3 251 28.4 4.59 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 10.75 1 0 5 17 8.562E8 10.68 8.00 4 8 853.44 10.75 5 9 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 10.75 1 0 5 17 8.562E8 10.68 8.00 4 8 853.44 10.75 5 9 400 44.1 5.14 HVO_1354 DNA mismatch repair protein MutS 10.69 1 5 5 12 2.157E8 4.23 10.69 5 6 384.45 10.69 5 6 580 62.1 4.56 HVO_1941 AAA-type ATPase (MoxR subfamily) 10.69 1 3 3 9 4.370E7 8.32 10.69 3 5 362.37 6.60 2 4 318 34.8 4.83 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 10.60 1 3 3 11 7.548E7 10.32 8.02 2 5 794.78 10.60 3 6 349 37.0 4.70 HVO_0448 imidazoleglycerol-phosphate synthase subunit HisH 10.50 1 2 2 7 1.281E8 4.38 10.50 2 4 288.26 10.50 2 3 219 23.4 4.23 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 10.48 1 5 5 18 1.435E8 15.97 10.48 5 9 1130.19 10.48 5 9 439 47.2 4.59 HVO_1439 cysteine synthase 10.43 1 2 2 4 5.794E7 1.81 10.43 2 2 126.78 10.43 2 2 326 34.7 4.53 HVO_B0004 serine hydroxymethyltransferase 10.36 1 1 2 3 4.527E9 261.10 10.36 2 3 415 44.4 4.46 HVO_1585 acyl-CoA synthetase 10.33 1 6 6 15 1.155E8 8.61 10.33 6 7 828.06 10.33 6 8 668 74.1 4.48 HVO_A0350 conserved hypothetical protein 10.33 1 2 2 6 1.762E8 6.69 10.33 2 3 380.03 10.33 2 3 213 23.8 9.64 HVO_0042 acetylornithine deacetylase 10.24 1 3 3 10 4.348E8 8.10 10.24 3 5 719.11 10.24 3 5 381 41.0 4.34 HVO_B0029 xylose dehydrogenase (NADP) 10.15 1 3 3 7 1.346E8 7.73 7.69 2 3 412.22 10.15 3 4 325 34.7 4.39 HVO_2153 probable copper-containing oxidoreductase 10.13 1 3 3 16 1.034E8 12.05 10.13 3 8 821.41 10.13 3 8 385 42.1 5.82 HVO_2998 homoserine O-acetyltransferase 10.12 1 3 3 9 1.202E8 4.14 10.12 3 5 422.98 7.71 2 4 415 44.8 4.69 HVO_0675 pantoate kinase 10.11 1 2 2 3 1.239E8 5.59 10.11 2 3 277 27.8 4.54 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 10.10 1 3 3 10 1.243E8 8.82 10.10 3 5 456.11 10.10 3 5 406 45.5 5.08 HVO_0522 HdaI-type histone deacetylase 10.09 1 2 2 7 7.607E7 10.10 10.09 2 3 728.76 10.09 2 4 337 36.3 4.45 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 10.06 1 3 3 12 1.528E8 4.29 10.06 3 6 439.79 10.06 3 6 348 36.7 4.69 HVO_0815 arNOG05395 family transcription regulator 10.04 1 2 2 7 8.697E7 3.63 10.04 2 4 285.45 10.04 2 3 259 26.9 4.42 HVO_0558 SAMP-activating enzyme E1 10.00 1 2 2 12 1.675E8 7.59 10.00 2 6 763.71 10.00 2 6 270 28.7 4.35 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 9.96 1 2 2 8 1.451E8 4.81 9.96 2 4 257.78 9.96 2 4 261 27.0 4.44 HVO_1936 F420-0:gamma-glutamyl ligase 9.96 1 2 2 7 1.482E8 4.33 9.96 2 3 374.10 9.96 2 4 251 27.4 4.68 HVO_1470 isochorismate synthase 9.93 1 2 2 10 1.393E8 4.09 9.93 2 5 361.98 9.93 2 5 443 47.7 4.56 HVO_B0266 glutamate dehydrogenase (NAD) 9.89 1 4 4 10 1.315E8 7.12 9.89 4 5 535.50 8.05 3 5 435 47.3 4.63 HVO_2906 tRNA (cytidine/uridine-2'-O-)-methyltransferase 9.82 1 2 2 6 5.287E7 2.22 9.82 2 3 284.28 9.82 2 3 275 30.6 4.58 HVO_2255 conserved hypothetical protein 9.75 1 2 2 6 5.581E7 4.07 9.75 2 3 268.21 9.75 2 3 236 27.7 5.60 HVO_0019 probable S-adenosylmethionine-dependent methyltransferase (homolog to 24-sterol C-methyltransferase) 9.73 1 2 2 9 1.946E8 9.36 9.73 2 4 564.61 9.73 2 5 226 25.6 4.64 HVO_0135 RIO-type serine/threonine protein kinase 9.66 1 3 3 8 8.521E7 1.80 9.66 3 4 387.87 9.66 3 4 290 33.0 4.81 31559829 keratin 25A [Homo sapiens] 9.56 1 1 2 3 6.572E8 4.47 9.56 2 3 450 49.3 5.08 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 9.54 1 3 3 7 7.364E7 0.00 9.54 3 3 198.03 9.54 3 4 388 41.9 4.35 HVO_2888 homolog to elongator complex protein ELP3 9.45 1 4 4 14 1.259E8 13.13 9.45 4 7 843.57 9.45 4 7 550 62.6 5.01 HVO_0896 acyl-CoA synthetase 9.44 1 5 5 20 1.184E8 15.73 9.44 5 10 1040.22 9.44 5 10 540 59.8 4.56 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 9.44 1 3 3 13 4.135E8 12.54 6.39 2 6 929.92 9.44 3 7 360 38.5 4.45 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 9.40 1 2 2 3 8.826E7 224.86 9.40 2 3 266 29.7 4.32 HVO_C0067 FAD-dependent oxidoreductase 9.34 1 4 4 13 1.645E8 14.36 9.34 4 7 607.39 9.34 4 6 396 42.7 4.30 HVO_2510 GNAT family acetyltransferase 9.21 1 2 2 6 1.095E8 4.00 9.21 2 3 305.44 9.21 2 3 304 33.7 4.49 HVO_2183 aldehyde ferredoxin oxidoreductase 9.18 1 4 4 12 5.710E7 9.51 9.18 4 6 560.86 9.18 4 6 643 69.3 4.59 HVO_2932 GTP-binding protein 9.09 1 3 3 12 9.948E7 6.30 9.09 3 6 579.11 9.09 3 6 396 43.5 4.51 HVO_1740 conserved hypothetical protein 9.05 1 2 2 6 5.978E7 2.12 9.05 2 3 240.32 9.05 2 3 210 24.4 4.49 HVO_A0545 TetR family transcription regulator 9.05 1 2 2 6 2.822E7 3.56 9.05 2 3 290.62 9.05 2 3 199 23.0 4.78 HVO_0483 RimK family protein 8.97 1 2 2 2 1.784E8 0.00 8.97 2 2 290 31.5 5.47 HVO_0831 ArgK-type transport ATPase 8.87 1 3 3 8 1.061E8 4.32 8.87 3 4 438.66 8.87 3 4 372 39.6 4.65 HVO_0724 ArsA family ATPase 8.80 1 3 3 8 5.939E7 6.17 8.80 3 4 422.25 8.80 3 4 409 43.9 4.22 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 8.78 1 3 4 13 1.189E8 3.49 8.78 4 7 527.88 7.66 3 6 444 47.1 4.77 HVO_A0306 4-aminobutyrate aminotransferase 8.76 1 3 3 10 7.548E7 9.81 8.76 3 5 705.92 8.76 3 5 445 47.6 4.68 HVO_0656 conserved hypothetical protein 8.71 1 2 2 6 1.085E7 0.00 8.71 2 3 128.16 8.71 2 3 241 26.3 6.11 HVO_1169 "probable glycosyltransferase, type 1" 8.70 1 4 4 9 4.032E7 1.73 5.16 3 4 315.30 8.70 4 5 368 40.8 4.73 HVO_0305 electron transfer flavoprotein beta subunit 8.68 1 2 2 10 4.620E8 6.85 8.68 2 5 484.37 8.68 2 5 265 28.5 4.04 HVO_0003 DNA-directed DNA polymerase D exonuclease subunit DP1 8.63 1 3 3 9 3.725E7 7.81 4.13 2 4 354.70 8.63 3 5 533 57.8 4.77 HVO_1368 probable metallo-beta-lactamase family hydrolase 8.61 1 2 2 5 3.629E8 7.77 8.61 2 5 267 29.3 4.49 HVO_0764 conserved hypothetical protein 8.46 1 1 2 5 3.239E8 0.00 8.46 2 3 80.83 8.46 2 2 260 28.2 4.79 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 8.38 1 4 4 12 1.413E8 11.01 8.38 4 6 675.82 8.38 4 6 573 62.9 4.45 HVO_2211 TrkA domain protein 8.37 1 2 2 6 1.024E8 6.48 8.37 2 3 266.28 8.37 2 3 227 24.5 4.72 HVO_C0057 Orc1-type DNA replication protein 8.37 1 3 3 12 4.757E7 11.76 8.37 3 6 769.93 8.37 3 6 418 46.3 5.02 HVO_0572 lipoate-protein ligase 8.36 1 2 2 4 5.445E7 7.29 8.36 2 2 401.74 8.36 2 2 275 30.5 4.84 HVO_2321 bacterial-type DNA primase DnaG 8.26 1 4 4 11 7.471E8 5.16 8.26 4 5 455.66 8.26 4 6 472 49.4 4.36 HVO_B0038A D-xylonate dehydratase 8.25 1 1 3 17 6.984E8 13.09 8.25 3 9 856.31 8.25 3 8 412 45.5 4.55 HVO_A0342 IclR family transcription regulator 8.12 1 2 2 7 3.218E7 5.82 8.12 2 4 245.68 8.12 2 3 271 30.6 5.19 HVO_1668 gamma-glutamylcysteine synthetase 8.10 1 3 3 10 3.285E7 3.81 8.10 3 5 528.47 8.10 3 5 358 39.9 4.72 HVO_1861 thiamine-monophosphate kinase 8.08 1 2 2 6 5.083E7 4.05 8.08 2 3 256.20 8.08 2 3 297 30.8 4.32 HVO_B0069 aldehyde dehydrogenase 8.06 1 2 2 4 3.593E7 2.42 8.06 2 2 139.74 8.06 2 2 459 50.1 4.74 HVO_1272 TrmB family transcription regulator 8.01 1 3 3 4 4.501E7 4.87 8.01 3 4 362 40.5 4.48 HVO_A0553 adenosylcobyric acid synthase 8.01 1 2 2 6 4.124E7 0.00 8.01 2 2 132.20 8.01 2 4 512 52.6 4.50 HVO_2158 malic enzyme (NADP) 7.99 1 0 4 18 8.332E8 24.27 7.99 4 9 1567.03 7.99 4 9 751 81.4 4.55 HVO_0968 NADH dehydrogenase-like complex subunit CD 7.98 1 0 5 28 1.578E9 18.95 7.98 5 14 1403.10 7.98 5 14 564 63.3 4.60 HVO_B0223 conserved hypothetical protein 7.94 1 2 2 5 4.836E7 5.98 7.94 2 3 295.18 7.94 2 2 277 29.8 4.51 HVO_A0001 Orc1-type DNA replication protein 7.93 1 2 2 4 5.097E7 2.18 7.93 2 2 152.51 7.93 2 2 416 47.0 4.97 HVO_A0064 Orc1-type DNA replication protein 7.82 1 2 2 6 5.003E7 1.71 7.82 2 3 178.69 7.82 2 3 499 55.5 4.91 HVO_A0524 3-hydroxyacyl-CoA dehydrogenase 7.82 1 2 2 6 6.944E7 8.99 7.82 2 3 499.10 7.82 2 3 294 31.3 4.45 HVO_2035 TrmB family transcription regulator 7.80 1 3 3 8 2.637E7 7.45 7.80 3 4 281.88 7.80 3 4 372 40.9 5.07 HVO_1779 transducer protein Htr8 7.79 1 2 2 2 3.104E8 0.00 7.79 2 2 603 65.0 4.46 HVO_1879 enoyl-CoA hydratase 7.79 1 2 2 4 5.269E7 2.35 7.79 2 2 197.08 7.79 2 2 231 24.3 5.21 HVO_A0180 SMC-like protein Sph1 7.76 1 3 4 9 1.420E8 3.99 7.76 4 5 281.85 7.76 4 4 593 66.4 4.58 HVO_2979 CobW domain protein 7.71 1 2 2 4 0.000E0 4.37 7.71 2 2 206.67 7.71 2 2 441 46.8 4.53 HVO_2767 ATP-dependent DNA helicase Dna2 7.69 1 6 6 18 3.536E7 11.69 7.69 6 9 837.15 7.69 6 9 884 97.5 4.86 HVO_2554 50S ribosomal protein L14 7.58 1 2 2 8 1.180E8 4.99 7.58 2 4 288.54 7.58 2 4 132 14.2 9.76 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 7.46 1 0 5 20 8.562E8 16.33 7.46 5 10 1110.10 7.46 5 10 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 7.46 1 0 5 20 8.562E8 16.33 7.46 5 10 1110.10 7.46 5 10 456 49.2 4.77 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 7.46 1 5 5 12 1.949E8 8.39 7.46 5 6 538.63 7.46 5 6 898 97.7 4.45 HVO_2448 probable oxidoreductase (aldo-keto reductase family protein) 7.34 1 2 2 3 4.685E7 198.38 7.34 2 3 327 36.5 4.94 HVO_2004 serine O-acetyltransferase 7.32 1 1 2 9 7.729E8 4.57 7.32 2 5 347.31 7.32 2 4 287 31.9 5.21 HVO_B0127 oxidoreductase (luciferase family protein) 7.26 1 3 3 9 5.016E7 2.10 7.26 3 4 374.98 7.26 3 5 317 35.7 4.60 HVO_1697 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 7.21 1 4 5 16 7.320E7 6.32 7.21 5 8 661.51 5.17 4 8 1026 111.2 4.54 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 7.11 1 4 4 11 9.519E7 5.50 7.11 4 6 539.03 3.26 3 5 858 93.9 4.69 HVO_B0055 conserved hypothetical protein 7.11 1 2 2 5 3.148E8 2.09 7.11 2 2 192.93 7.11 2 3 225 23.9 4.69 HVO_1228 halocyanin 7.06 1 5 5 11 8.151E7 6.91 7.06 5 6 474.22 5.72 4 5 821 83.7 4.17 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 6.96 1 2 2 4 2.811E7 1.78 6.96 2 2 153.66 6.96 2 2 359 39.4 4.91 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 14 1.456E9 7.57 6.94 3 7 775.26 6.94 3 7 389 40.8 4.89 31074633 keratin 6L [Homo sapiens] 6.92 1 0 4 10 4.066E8 8.42 6.92 4 5 765.49 6.92 4 5 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 6.92 1 0 4 10 4.066E8 8.42 6.92 4 5 765.49 6.92 4 5 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 6.92 1 0 4 10 4.066E8 8.42 6.92 4 5 765.49 6.92 4 5 535 57.7 7.20 HVO_2369 conserved hypothetical protein 6.84 1 3 3 6 3.264E6 2.02 6.84 3 3 274.64 6.84 3 3 424 47.3 5.06 HVO_0687 M20 family amidohydrolase 6.76 1 3 3 7 5.439E7 2.55 4.28 2 3 335.16 6.76 3 4 444 47.5 4.58 HVO_0286 CinA N-terminal domain protein 6.57 1 2 2 4 2.541E7 1.69 6.57 2 2 87.59 6.57 2 2 274 28.9 4.22 HVO_2175 SMC-like protein Sph3 6.57 1 2 2 2 1.964E8 48.23 6.57 2 2 654 74.2 4.54 HVO_A0254 DUF234 domain protein 6.51 1 4 4 10 5.702E7 2.26 6.51 4 5 441.27 6.51 4 5 461 52.7 4.78 HVO_A0159 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 6.46 1 2 2 6 8.625E7 3.59 6.46 2 3 190.89 6.46 2 3 387 42.7 4.44 HVO_2311 glutamyl-tRNA reductase 6.29 1 3 3 7 5.181E7 3.98 4.12 2 3 348.10 6.29 3 4 461 49.2 4.54 HVO_A0562 urocanate hydratase 6.29 1 3 3 14 8.290E7 14.54 6.29 3 7 1051.81 6.29 3 7 620 67.9 4.70 HVO_0591 L-threonine-O-3-phosphate decarboxylase 6.18 1 2 2 3 4.408E7 121.30 6.18 2 3 340 36.0 4.54 HVO_2640 conserved hypothetical protein 6.15 1 2 2 6 5.832E7 0.00 6.15 2 3 217.45 6.15 2 3 309 33.9 4.56 HVO_C0074 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 6.09 1 3 3 8 6.460E7 4.13 6.09 3 3 339.29 6.09 3 5 690 75.9 4.79 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 5.95 1 2 2 8 3.387E8 7.02 5.95 2 4 409.08 5.95 2 4 353 36.7 4.65 HVO_1047 NADPH:quinone reductase 5.88 1 2 2 6 2.223E7 4.73 5.88 2 3 309.33 5.88 2 3 323 33.8 4.27 HVO_2812 AstE family protein 5.87 1 2 2 3 1.509E8 2.77 5.87 2 3 341 37.3 5.14 4504919 keratin 8 [Homo sapiens] 5.80 1 0 4 36 2.665E8 23.60 5.80 4 18 2138.82 5.80 4 18 483 53.7 5.59 HVO_1596 DUF790 family protein 5.80 1 2 2 6 4.925E7 2.12 5.80 2 3 253.10 5.80 2 3 500 53.9 4.65 18031720 keratin protein K6irs [Homo sapiens] 5.49 1 0 3 11 1.684E8 9.06 5.49 3 5 510.84 5.49 3 6 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 5.48 1 0 3 11 1.684E8 9.06 5.48 3 5 510.84 5.48 3 6 511 55.8 6.89 HVO_2071 conserved hypothetical protein 5.46 1 3 3 12 1.385E8 12.11 5.46 3 6 882.80 5.46 3 6 549 58.4 4.72 4504911 keratin 13 isoform b [Homo sapiens] 5.24 1 0 3 12 1.474E8 9.83 5.24 3 6 640.35 5.24 3 6 420 45.8 4.88 HVO_1735 conserved hypothetical protein 5.15 1 5 5 12 2.777E7 3.67 5.15 5 6 500.80 5.15 5 6 660 75.7 4.50 HVO_1309 peptidase M24 family protein 5.12 1 2 2 10 4.692E8 9.93 5.12 2 5 577.96 5.12 2 5 391 42.1 4.36 HVO_0148 urease alpha subunit 5.11 1 2 2 4 3.001E7 2.32 5.11 2 2 169.32 5.11 2 2 568 60.3 4.54 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 5.04 1 2 2 8 5.863E7 5.73 5.04 2 4 430.09 5.04 2 4 337 35.9 4.39 HVO_B0146 aminotransferase class V 5.04 1 2 2 2 5.040E7 95.78 5.04 2 2 377 41.2 4.93 HVO_0311 A-type ATP synthase subunit I 4.91 1 3 3 10 9.029E7 5.53 4.91 3 5 407.48 4.91 3 5 733 79.5 4.41 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 4.80 1 0 3 12 1.474E8 9.83 4.80 3 6 640.35 4.80 3 6 458 49.6 4.96 HVO_B0257 4-aminobutyrate aminotransferase 4.79 1 2 2 8 3.276E7 3.77 4.79 2 4 238.71 4.79 2 4 459 49.3 4.92 HVO_2482 HD family hydrolase 4.68 1 0 2 8 8.905E7 2.11 4.68 2 4 405.75 4.68 2 4 406 44.7 4.89 HVO_0038 cytochrome P450 4.59 1 2 2 2 4.087E7 49.25 4.59 2 2 458 52.2 4.89 109255249 keratin 4 [Homo sapiens] 4.55 1 0 3 6 2.068E8 5.08 4.55 3 3 410.96 4.55 3 3 594 63.9 8.25 HVO_1564 conserved hypothetical protein 4.52 1 2 2 3 1.176E8 240.45 4.52 2 3 509 56.5 4.65 HVO_2381 UPF0272 family protein 4.46 1 2 2 8 4.355E7 3.85 4.46 2 4 274.44 4.46 2 4 493 52.3 4.88 HVO_0757 probable oxidoreductase (aldo-keto reductase family protein) 4.41 1 2 2 5 2.293E7 2.08 4.41 2 3 164.97 4.41 2 2 363 39.1 4.77 HVO_0140 conserved hypothetical protein 4.35 1 2 2 4 2.724E7 0.00 4.35 2 2 74.02 4.35 2 2 689 77.5 4.77 HVO_2911 deoxyribodipyrimidine photolyase 4.34 1 2 2 4 7.315E6 1.74 4.34 2 2 132.06 4.34 2 2 484 54.5 4.79 HVO_0065 DNA-directed DNA polymerase D large subunit 4.33 1 3 3 6 6.962E7 2.52 4.33 3 3 159.60 4.33 3 3 1202 133.9 4.60 HVO_2860 conserved hypothetical protein 4.27 1 2 2 2 8.398E7 0.00 4.27 2 2 562 58.9 4.49 HVO_2605 MiaB-like tRNA modifying enzyme 4.20 1 2 2 4 3.182E7 2.18 4.20 2 2 233.59 4.20 2 2 429 47.4 5.03 HVO_2575 homolog to translation elongation factor aEF-1 alpha subunit 4.12 1 2 2 4 2.831E7 0.00 4.12 2 2 144.00 4.12 2 2 534 57.8 4.81 HVO_2598 polyphosphate kinase 4.02 1 2 2 5 5.320E7 0.00 4.02 2 2 167.69 4.02 2 3 747 83.6 5.11 HVO_0073 single-stranded-DNA-specific exonuclease RecJ1 3.99 1 2 2 4 3.553E7 0.00 3.99 2 2 153.41 3.99 2 2 476 50.6 4.68 HVO_1940 DNA mismatch repair protein MutS 3.80 1 3 3 10 3.505E7 5.88 3.80 3 5 526.16 3.80 3 5 921 99.4 4.42 HVO_1916 Kef-type transport system (probable substrate potassium) 3.78 1 3 3 7 1.526E8 0.00 3.78 3 4 204.44 3.78 3 3 635 66.2 4.63 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 9 2.451E8 6.67 3.63 2 4 427.61 3.63 2 5 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.59 1 0 2 9 2.451E8 6.67 3.59 2 4 427.61 3.59 2 5 529 57.8 7.71 28173564 keratin 6 irs3 [Homo sapiens] 3.52 1 0 2 9 2.451E8 6.67 3.52 2 4 427.61 3.52 2 5 540 58.9 7.23 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 8 8.539E8 6.24 3.45 2 4 538.06 3.45 2 4 464 50.6 5.47 HVO_B0149 oleate hydratase 3.38 1 1 2 5 5.178E8 1.63 3.38 2 2 186.34 3.38 2 3 533 60.1 4.64 31074631 keratin 1b [Homo sapiens] 3.29 1 0 2 6 1.318E9 6.12 3.29 2 3 486.49 3.29 2 3 578 61.8 5.97 HVO_0418 homolog to haloviral protein 3.21 1 2 2 6 1.148E7 1.62 3.21 2 3 186.60 3.21 2 3 498 57.6 5.22 27894337 keratin 20 [Homo sapiens] 2.59 1 0 2 8 6.795E7 7.31 2.59 2 4 477.20 2.59 2 4 424 48.5 5.69 HVO_A0209 CRISPR-associated helicase Cas3 2.45 1 2 2 4 3.176E7 2.54 2.45 2 2 142.51 2.45 2 2 937 103.6 4.93 HVO_B0265 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 1.62 1 1 2 2 4.412E8 0.00 1.62 2 2 1048 112.5 4.61