Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0356 translation elongation factor aEF-2 81.84 1 48 48 952 3.081E10 849.61 76.89 45 466 55336.45 81.84 48 486 727 80.4 4.73 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 78.87 1 17 17 199 9.211E9 238.33 78.87 17 99 15057.24 78.87 17 100 355 38.2 4.68 HVO_0359 translation elongation factor aEF-1 alpha subunit 78.86 1 22 25 1334 7.141E10 1175.78 73.16 22 625 92794.96 78.86 25 709 421 45.7 4.73 HVO_0329 branched-chain amino acid aminotransferase 77.56 1 17 17 95 3.206E9 99.60 77.56 17 47 6585.99 77.56 17 48 312 35.0 4.58 HVO_1454 aspartate carbamoyltransferase catalytic subunit 76.97 1 13 13 50 5.290E8 35.70 63.82 12 25 2977.75 76.97 13 25 304 33.7 4.92 HVO_0989 conserved hypothetical protein 75.40 1 8 8 27 4.019E8 12.71 75.40 8 14 1281.79 69.05 7 13 126 14.4 4.81 HVO_0433 F420H2:NADP oxidoreductase 75.23 1 9 9 31 1.314E9 29.55 58.11 8 15 2039.31 75.23 9 16 222 23.3 4.72 HVO_0880 conserved hypothetical protein 74.92 1 25 25 216 4.233E9 240.80 68.40 23 106 16240.24 74.92 25 110 307 36.3 4.74 HVO_2900 fumarate hydratase 69.08 1 20 20 181 8.357E9 156.07 67.16 19 88 10459.26 69.08 20 93 469 50.1 4.78 HVO_1921 serine--tRNA ligase 67.61 1 24 24 143 2.427E9 138.13 67.61 24 73 9094.73 66.30 23 70 460 52.0 4.46 HVO_2862 serine hydroxymethyltransferase 66.99 1 16 16 221 9.385E9 190.95 65.06 15 111 12812.60 66.99 16 110 415 44.3 4.53 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 66.57 1 15 15 134 6.596E9 131.01 66.57 15 67 9280.73 66.57 15 67 350 37.6 4.54 HVO_A0207 CRISPR-associated protein Cas7 64.12 1 12 12 73 2.534E9 74.51 64.12 12 38 4514.39 64.12 12 35 340 38.2 4.54 HVO_0133 thermosome subunit 1 63.93 1 22 24 214 7.457E9 200.85 63.93 24 106 14700.18 58.57 23 108 560 58.9 4.25 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 62.28 1 14 14 72 1.744E9 64.23 62.28 14 35 4199.47 62.28 14 37 281 30.6 4.59 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 61.93 1 18 18 98 2.370E9 98.53 61.93 18 49 6096.48 61.49 17 49 457 48.4 4.35 HVO_0104 DNA repair and recombination protein RadA 61.81 1 15 15 86 3.850E9 88.42 56.56 14 42 6058.02 61.81 15 44 343 37.3 4.64 HVO_0581 "cell division protein FtsZ, type II" 61.75 1 17 17 84 1.863E9 97.33 57.00 16 41 6174.43 61.75 17 43 400 42.5 4.75 HVO_2588 isocitrate dehydrogenase (NADP) 61.34 1 22 22 195 1.351E10 214.11 58.23 21 99 13184.08 61.34 22 96 419 45.8 4.59 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 61.27 1 27 27 119 2.207E9 139.37 60.60 26 58 9003.11 61.27 27 61 599 65.3 4.51 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 60.93 1 15 15 78 1.144E9 74.54 60.93 15 39 5334.33 60.93 15 39 343 38.4 4.94 HVO_0677 aspartate--tRNA ligase 60.83 1 19 19 281 1.115E10 287.01 60.83 19 140 19056.09 60.83 18 141 434 48.7 4.50 HVO_0870 proline--tRNA ligase 60.66 1 18 18 108 2.796E9 94.25 58.20 17 53 6709.53 60.66 18 55 488 54.9 4.44 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 60.63 1 10 10 38 1.189E9 26.25 56.30 9 19 2113.88 60.63 10 19 254 26.9 4.42 HVO_0239 glutamine synthetase 60.53 1 22 22 159 8.469E9 124.22 60.53 21 79 9023.37 58.99 18 80 456 50.5 4.56 HVO_0602 3-dehydroquinate dehydratase 60.32 1 11 11 52 7.858E8 37.86 56.68 10 24 3107.27 60.32 11 28 247 27.3 4.51 HVO_2724 beta-lactamase domain protein 59.33 1 19 19 188 6.097E9 177.79 59.33 19 96 11293.11 54.00 18 92 450 50.1 5.40 HVO_2413 translation elongation factor aEF-1 alpha subunit 59.29 1 15 18 216 1.242E10 145.89 53.33 16 98 12989.98 59.29 18 118 420 45.6 4.75 HVO_2783 30S ribosomal protein S4 58.86 1 10 10 48 1.749E9 29.87 54.86 9 23 2867.32 58.86 10 25 175 20.1 5.24 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 58.85 1 16 16 134 7.197E9 191.24 58.85 16 68 12272.98 58.85 16 66 384 41.4 4.41 HVO_0778 thermosome subunit 3 58.40 1 21 23 197 4.142E9 227.47 58.40 23 99 14102.04 58.40 23 98 524 55.2 4.59 HVO_0455 thermosome subunit 2 58.35 1 28 29 314 6.347E9 240.33 58.35 28 156 17646.38 58.35 29 158 557 59.3 4.37 HVO_0167 adenosylhomocysteinase 57.94 1 18 18 106 1.723E9 84.93 53.74 17 52 6701.67 51.64 17 54 428 46.6 4.39 HVO_1637 FKBP-type peptidylprolyl isomerase 57.52 1 8 9 63 6.866E9 43.92 49.02 8 26 4621.31 57.52 9 37 306 33.8 3.76 HVO_1273 inosine-5'-monophosphate dehydrogenase 57.43 1 19 19 210 4.363E9 179.05 54.82 18 107 12069.63 57.43 19 103 498 53.3 4.55 HVO_2435 peptidase M24 family protein 57.34 1 14 14 55 8.715E8 47.26 57.34 14 25 3623.00 57.34 14 30 368 40.0 4.53 HVO_0348 DNA-directed RNA polymerase subunit B' 56.98 1 26 26 187 3.430E9 181.46 56.98 26 96 11763.96 56.98 26 91 609 67.7 4.92 HVO_2969 threonine synthase 56.80 1 17 17 86 3.416E9 76.12 52.27 16 41 5156.69 56.80 17 45 419 44.4 4.49 HVO_1914 acetyl-CoA C-acyltransferase 56.76 1 11 11 56 1.987E9 45.13 54.11 10 27 3082.09 56.76 11 29 377 39.9 4.41 HVO_1507 acetolactate synthase small subunit 56.42 1 10 10 44 6.745E8 53.70 56.42 10 22 3267.48 56.42 10 22 218 23.7 4.94 HVO_0400 conserved hypothetical protein 56.35 1 4 4 13 2.628E8 8.96 34.13 3 6 644.60 56.35 4 7 126 13.9 4.68 HVO_2968 phosphoglycerate dehydrogenase 56.19 1 19 19 204 1.039E10 239.99 56.19 19 101 15634.14 50.67 18 103 525 55.3 4.36 HVO_0025 thiosulfate sulfurtransferase 55.94 1 9 9 194 1.773E10 119.86 55.94 9 95 9926.38 55.94 9 99 286 32.1 4.28 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 55.28 1 13 13 75 1.959E9 48.97 51.67 12 39 3812.39 55.28 13 36 360 39.6 4.39 HVO_2621 phosphoenolpyruvate carboxylase 55.18 1 39 40 262 3.908E9 243.73 55.18 40 130 15346.55 54.63 39 132 897 102.3 4.64 HVO_1189 aldehyde dehydrogenase 55.12 1 22 22 190 7.746E9 143.82 47.83 21 95 10840.91 55.12 22 95 508 56.1 4.59 HVO_0347 DNA-directed RNA polymerase subunit B'' 55.09 1 26 26 166 2.898E9 118.85 55.09 26 84 9998.62 55.09 26 82 521 58.9 5.00 HVO_0055 CBS domain protein 54.93 1 10 10 68 2.674E9 61.05 54.93 10 34 4475.71 54.93 10 34 284 30.8 4.27 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 54.86 1 13 13 175 1.554E10 136.96 54.86 13 87 10034.57 54.86 13 88 381 41.0 4.23 HVO_1955 aconitate hydratase 54.74 1 28 28 324 2.358E10 350.17 54.43 27 164 22833.49 46.33 26 160 654 70.4 4.45 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 54.24 1 14 14 102 5.964E9 99.08 54.24 14 51 6669.12 54.24 14 51 413 45.8 4.45 HVO_0480 phosphoglycerate kinase 54.11 1 17 17 75 2.252E9 70.43 46.38 16 37 5125.48 54.11 17 38 401 43.6 4.37 HVO_0240 Lrp/AsnC family transcription regulator 53.95 1 7 8 27 1.046E9 19.60 48.68 7 12 1984.10 53.95 8 15 152 16.9 4.39 HVO_1506 ketol-acid reductoisomerase 53.74 1 11 11 65 2.101E9 59.57 51.15 10 32 3796.42 43.39 10 33 348 37.9 4.34 HVO_0861 SufB domain protein 53.48 1 15 15 103 5.129E9 119.22 50.00 14 51 8082.32 53.48 15 52 402 44.7 4.23 HVO_1690 DHH family phosphoesterase 53.40 1 15 15 69 8.410E8 75.75 50.72 14 35 4736.91 45.77 13 34 485 52.1 4.48 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 53.38 1 21 21 138 5.606E9 142.98 53.38 20 70 8484.63 46.96 20 68 592 66.6 4.61 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 53.16 1 16 16 95 1.429E9 92.81 53.16 16 48 5967.03 53.16 16 47 474 53.4 4.59 HVO_0999 DRTGG domain protein 52.65 1 14 14 68 1.577E9 64.85 48.94 13 34 4560.19 52.65 14 34 378 39.8 4.44 HVO_0869 glutamate synthase large subunit 52.35 1 59 60 396 4.702E9 399.54 51.89 59 198 28081.80 50.43 59 198 1511 163.8 4.70 HVO_0175 DNA polymerase sliding clamp 52.23 1 10 10 100 5.866E9 80.48 46.56 8 49 5808.07 50.61 9 51 247 26.7 4.39 HVO_2013 "FtsZ family protein, type III" 52.03 1 10 10 44 7.382E8 42.03 52.03 10 22 3012.12 52.03 10 22 394 41.5 4.61 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 51.95 1 8 8 29 6.262E8 20.68 51.95 8 15 1710.29 41.99 7 14 231 25.0 4.25 HVO_1284 GTP cyclohydrolase III 51.72 1 9 9 37 4.983E8 30.45 42.91 8 18 2270.64 51.72 9 19 261 28.9 4.70 HVO_0313 A-type ATP synthase subunit E 51.55 1 6 6 25 7.092E8 25.20 44.33 5 12 1684.09 38.66 5 13 194 22.0 4.31 HVO_2384 CBS domain protein 51.05 1 17 17 181 6.546E9 156.70 48.68 16 90 11210.15 51.05 17 91 380 42.5 5.01 HVO_A0458 ParA domain protein 50.86 1 9 9 26 3.283E8 17.59 50.86 9 13 1252.31 50.86 9 13 291 32.2 4.79 HVO_0859 FeS assembly ATPase SufC 50.50 1 13 13 143 4.775E9 112.81 50.50 13 72 8877.30 50.50 13 71 301 33.4 4.35 HVO_0850 proteasome-activating nucleotidase 50.37 1 15 15 114 1.579E9 98.78 45.19 14 59 6517.69 50.37 15 55 405 45.6 4.60 HVO_1502 3-isopropylmalate dehydrogenase 50.31 1 12 12 75 3.669E9 55.15 42.59 11 35 5141.62 50.31 12 40 324 33.7 4.23 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 50.30 1 10 10 69 1.319E9 70.46 40.18 8 32 5352.52 50.30 10 37 336 36.8 4.12 HVO_2015 conserved hypothetical protein 50.14 1 12 12 182 2.066E10 204.85 50.14 12 91 13073.91 50.14 12 91 345 37.7 4.25 HVO_2726 glutamate--tRNA ligase 50.09 1 22 22 97 1.170E9 61.78 50.09 22 50 4672.32 50.09 22 47 585 65.2 4.58 HVO_0310 A-type ATP synthase subunit H 50.00 1 3 3 8 2.918E8 2.09 50.00 3 4 183.35 50.00 3 4 110 12.5 4.03 HVO_2700 AAA-type ATPase (CDC48 subfamily) 49.87 1 31 32 147 1.142E9 95.85 49.87 32 73 7213.58 49.87 32 74 754 82.8 4.75 HVO_2774 enolase 49.87 1 12 12 83 3.806E9 93.99 49.87 12 42 5459.15 48.12 11 41 399 42.0 4.37 HVO_B0118 SMC-like protein Sph2 49.84 1 29 29 170 3.583E9 177.09 47.67 28 86 10409.52 49.84 29 84 644 73.8 4.41 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 49.68 1 22 22 147 2.771E9 130.94 49.68 22 75 9318.54 49.68 22 72 624 67.6 4.27 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 49.65 1 10 10 50 1.098E9 37.42 49.65 10 25 2542.06 49.65 10 25 286 31.2 4.54 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 49.52 1 22 22 110 1.414E9 99.35 49.52 22 55 6746.20 49.52 22 55 626 67.6 4.65 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 49.46 1 7 7 31 1.193E9 28.72 44.02 6 14 2326.16 49.46 7 17 184 19.8 5.30 HVO_2552 30S ribosomal protein S4e 49.39 1 9 9 101 1.121E10 76.55 49.39 9 50 5193.41 49.39 9 51 247 26.6 4.58 HVO_2889 RecJ domain protein 49.25 1 28 28 235 8.758E9 213.23 49.25 28 117 15621.54 49.25 28 118 729 79.1 4.37 HVO_0203 replication factor C small subunit 49.24 1 14 14 54 9.005E8 54.13 46.48 13 27 3483.40 49.24 14 27 327 36.2 4.51 HVO_0161 ATP phosphoribosyltransferase 49.11 1 11 11 58 1.319E9 53.36 49.11 11 30 3365.90 49.11 11 28 281 30.4 4.60 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 49.04 1 9 9 125 7.333E9 119.90 49.04 9 64 7334.90 49.04 9 61 312 34.5 4.98 HVO_2519 conserved hypothetical protein 48.95 1 13 13 104 2.183E9 86.02 44.24 12 51 6648.40 48.95 13 53 382 40.7 4.35 HVO_1132 adenylosuccinate synthase 48.76 1 22 22 185 6.084E9 142.51 45.60 21 93 10396.58 48.76 21 92 443 48.2 4.56 HVO_0789 tryptophan synthase alpha subunit 48.74 1 8 8 54 9.142E8 52.37 48.74 8 29 3394.77 48.74 8 25 277 29.6 4.21 HVO_0317 A-type ATP synthase subunit B 48.72 1 13 14 120 7.953E9 143.14 44.23 13 58 9378.01 48.72 14 62 468 51.9 4.25 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 48.54 1 13 13 68 1.372E9 73.61 46.97 12 34 4566.55 48.54 13 34 445 47.8 4.86 HVO_0860 SufB domain protein 48.53 1 16 16 127 5.146E9 107.96 45.38 15 60 7832.05 41.81 15 67 476 53.2 4.69 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 48.51 1 15 15 63 1.128E9 43.38 48.51 15 32 3743.84 48.51 15 31 336 38.0 4.61 HVO_0467 PhoU/TrkA-C domain protein 48.26 1 16 16 62 5.832E8 50.18 48.26 16 31 3538.28 48.26 16 31 402 43.3 4.49 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 48.20 1 16 16 77 3.313E9 49.11 42.62 14 34 5137.11 48.20 16 43 305 33.8 4.74 HVO_A0156 acyl-CoA synthetase 48.04 1 11 22 181 6.801E9 177.08 46.54 21 86 12907.77 48.04 22 95 664 74.0 4.40 HVO_0206 alanine--tRNA ligase 47.94 1 31 31 162 1.417E9 121.34 43.38 29 78 9862.07 47.94 31 84 922 102.4 4.54 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 47.89 1 6 6 32 1.458E9 33.06 47.89 6 16 2283.91 47.89 6 16 190 20.6 4.30 HVO_0894 acyl-CoA synthetase 47.73 1 12 23 204 6.784E9 208.16 46.22 22 97 14907.81 47.73 23 107 662 74.3 4.48 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 47.65 1 14 14 57 9.092E8 50.50 47.65 14 29 3537.23 47.65 14 28 340 38.8 4.58 HVO_1373 acyl-CoA dehydrogenase 47.52 1 11 11 92 3.081E9 99.81 47.52 11 47 6604.96 47.52 11 45 383 42.5 4.61 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 47.46 1 13 13 64 1.448E9 52.58 47.46 13 32 3865.04 47.46 13 32 453 47.5 4.63 HVO_2191 formyltetrahydrofolate deformylase 47.40 1 12 12 63 1.851E9 52.54 47.40 12 31 3960.90 47.40 12 32 327 36.2 4.63 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 47.33 1 23 23 101 1.218E9 88.90 45.17 22 50 6034.46 47.33 23 51 600 65.3 4.68 HVO_2544 30S ribosomal protein S5 47.20 1 9 9 39 3.869E9 37.32 30.37 6 19 2402.90 44.86 8 20 214 23.3 9.29 HVO_2130 IclR family transcription regulator 47.06 1 9 9 39 4.946E8 28.51 47.06 9 20 2278.13 38.60 8 19 272 30.1 5.55 HVO_2225 AstE family protein 46.92 1 9 9 44 1.295E9 49.38 46.92 9 22 2878.97 39.00 8 22 341 36.9 4.53 HVO_2756 50S ribosomal protein L10 46.84 1 9 9 44 1.895E9 36.47 46.84 9 22 2447.30 46.84 9 22 348 36.9 3.99 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 46.69 1 9 9 119 4.960E9 120.98 43.90 8 61 8345.84 46.69 9 58 287 31.0 4.73 HVO_A0206 CRISPR-associated protein Cas8b 46.58 1 25 25 141 2.548E9 106.13 46.58 25 70 8019.66 46.58 25 71 717 79.3 4.60 HVO_2961 dihydrolipoyl dehydrogenase 46.53 1 14 14 81 1.061E9 89.34 41.05 13 38 6037.90 46.53 14 43 475 49.9 4.41 HVO_2059 NAD-dependent epimerase/dehydratase 46.45 1 10 10 52 2.318E9 39.44 46.45 10 25 3083.21 46.45 10 27 310 34.1 4.40 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 131 5.953E9 126.96 43.25 7 65 8642.25 46.37 8 66 289 29.8 4.27 HVO_1145 30S ribosomal protein S1e 46.36 1 9 9 40 8.878E8 36.33 46.36 9 19 2728.88 46.36 9 21 220 24.8 4.86 HVO_2204 "FtsZ family protein, type III" 46.33 1 13 15 87 3.605E9 94.85 46.33 15 43 6459.34 46.33 15 44 395 42.0 4.68 HVO_1541 glycerol kinase 45.88 1 17 17 106 5.325E9 81.46 42.55 16 51 6423.99 45.88 17 55 510 56.7 4.50 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 45.84 1 19 19 116 3.299E9 95.18 36.76 17 59 6408.71 44.78 18 57 661 71.0 4.35 HVO_1140 acyl-CoA dehydrogenase 45.79 1 12 12 60 1.332E9 39.72 45.79 12 28 3616.99 45.79 12 32 380 41.2 4.55 HVO_0393 UvrABC system protein A 45.78 1 35 35 138 8.419E8 121.96 44.96 34 65 7205.07 45.78 35 73 983 108.6 4.82 HVO_2487 aspartate-semialdehyde dehydrogenase 45.64 1 9 9 92 4.788E9 78.75 45.64 9 45 4961.62 45.64 9 47 344 36.6 4.41 HVO_0809 methionine--tRNA ligase 45.27 1 23 23 111 1.930E9 102.85 45.27 23 55 7345.48 43.65 22 56 740 81.9 4.37 HVO_1684 threonine--tRNA ligase 45.26 1 25 25 143 3.873E9 126.21 44.32 24 71 8389.84 44.01 24 72 643 73.4 4.45 HVO_0324 arginine--tRNA ligase 45.14 1 23 23 129 2.875E9 118.92 45.14 23 63 7922.93 45.14 23 66 587 65.0 4.35 HVO_0829 peptidase S9 family protein 45.07 1 18 18 61 1.190E9 29.60 45.07 18 30 2882.24 45.07 18 31 608 67.4 4.54 HVO_1649 methionine adenosyltransferase 44.78 1 12 12 64 1.081E9 54.38 44.78 12 31 3856.89 44.78 12 33 402 43.5 4.45 HVO_2336 pyridoxal biosynthesis lyase PdxS 44.70 1 11 11 57 6.960E8 36.59 41.06 9 27 3439.27 44.70 11 30 302 32.5 4.81 HVO_2646 dihydroxy-acid dehydratase 44.69 1 17 17 152 4.020E9 157.03 44.69 17 76 10788.48 44.69 17 76 584 61.8 4.42 HVO_1338 replication protein A 44.50 1 11 11 56 8.023E8 58.52 44.50 11 28 3201.47 44.50 11 28 427 46.0 4.36 HVO_1031 thioredoxin-disulfide reductase 44.44 1 11 11 50 9.469E8 48.47 44.44 11 25 3367.42 44.44 11 25 342 37.4 4.46 HVO_0449 prephenate dehydratase 44.40 1 9 9 45 1.255E9 40.88 42.16 8 22 2767.61 44.40 9 23 268 28.7 4.64 HVO_B0001 Orc1-type DNA replication protein 44.39 1 13 14 33 2.584E8 11.74 33.66 12 16 1161.74 44.39 14 17 410 45.8 5.33 HVO_0980 NADH dehydrogenase-like complex subunit CD 44.34 1 15 19 90 1.574E9 66.70 44.34 19 47 4984.30 36.27 18 43 557 63.4 4.53 HVO_0424 ABC-type transport system ATP-binding protein 44.21 1 18 18 76 1.039E9 64.15 38.08 16 36 4330.29 44.21 18 40 604 67.2 4.49 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 44.06 1 19 19 357 1.753E10 369.61 42.79 18 180 24009.64 43.26 18 177 631 68.4 4.49 HVO_0788 tryptophan synthase beta subunit 43.84 1 11 11 51 9.767E8 42.09 43.84 11 26 2509.08 43.84 11 25 422 45.7 4.65 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 43.81 1 16 16 95 3.546E9 100.24 40.76 13 46 6447.28 43.81 16 49 525 56.4 4.40 HVO_0243 threonine aldolase 43.70 1 10 10 55 3.928E8 55.46 43.70 10 26 4013.38 43.70 10 29 341 35.6 4.55 HVO_2948 phenylalanine--tRNA ligase alpha subunit 43.69 1 10 10 53 1.067E9 48.99 36.47 9 25 3605.34 43.69 10 28 499 55.1 4.41 HVO_0792 3-dehydroquinate synthase type II 43.62 1 14 14 79 1.650E9 77.37 43.62 13 38 4791.82 43.62 14 41 392 43.1 4.44 HVO_2419 hydroxymethylglutaryl-CoA synthase 43.60 1 14 14 89 3.421E9 68.10 43.60 14 43 4625.67 43.60 14 46 445 50.1 4.64 HVO_0212 homolog to lactoylglutathione lyase 43.55 1 3 3 16 5.864E8 25.85 43.55 3 8 1578.33 43.55 3 8 124 13.5 4.13 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 43.55 1 16 16 94 2.425E9 84.05 43.55 16 46 5725.40 43.55 16 48 512 53.8 4.78 HVO_1965 rRNA maturation endonuclease Nob1 43.42 1 3 3 4 2.713E8 1.96 43.42 3 4 152 16.8 4.70 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 43.39 1 13 13 53 7.714E8 45.09 43.39 13 27 2831.70 43.39 13 26 454 48.5 4.46 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 43.37 1 11 11 38 7.068E8 27.26 40.33 10 19 1957.69 43.37 10 19 362 39.6 4.82 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 43.17 1 21 21 266 1.037E10 232.89 43.17 21 137 16739.10 43.17 21 129 586 64.0 4.49 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 43.03 1 10 10 62 1.073E9 75.33 43.03 10 31 4371.13 43.03 10 31 330 36.3 4.35 HVO_2624 CTP synthase 42.81 1 17 17 100 2.750E9 65.60 40.62 15 48 5534.92 42.81 17 52 549 60.8 4.70 HVO_2558 30S ribosomal protein S3 42.76 1 10 10 130 5.668E9 135.21 38.49 9 64 9414.01 40.13 9 66 304 33.4 4.06 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 42.76 1 8 8 52 1.571E9 33.78 38.05 7 25 2444.96 42.76 8 27 297 31.3 4.36 HVO_0008 aspartate kinase 42.60 1 9 9 48 3.451E9 34.34 42.60 9 24 2446.76 42.60 9 24 392 41.7 4.46 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.48 1 9 9 41 1.336E9 32.43 42.48 9 20 2708.76 42.48 9 21 266 27.8 4.84 HVO_1084 adenylosuccinate lyase 42.12 1 16 16 66 7.746E8 54.84 32.83 13 31 4295.54 42.12 16 35 463 50.8 4.70 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 42.08 1 9 9 44 1.630E9 49.04 42.08 9 22 3416.25 42.08 9 22 259 28.0 4.50 HVO_0415 repair helicase 42.05 1 20 20 95 1.229E9 92.87 40.58 19 46 6853.11 42.05 20 49 616 69.6 4.70 HVO_1082 homolog to orotate phosphoribosyltransferase 41.90 1 6 6 21 6.282E8 16.31 41.90 6 11 1189.36 31.90 5 10 210 22.3 4.42 HVO_0743 probable phosphodiesterase 41.87 1 21 21 140 2.497E9 121.08 41.87 21 70 9145.14 40.98 20 70 449 50.5 4.56 HVO_1824 conserved hypothetical protein 41.72 1 13 13 55 7.213E8 59.91 41.72 13 28 3818.42 41.72 13 27 429 47.4 4.20 HVO_1504 3-isopropylmalate dehydratase large subunit 41.65 1 15 16 118 5.499E9 133.22 41.65 16 59 8301.95 41.65 16 59 473 51.6 4.55 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 41.43 1 9 9 66 2.016E9 76.25 41.43 9 33 4652.25 39.64 8 33 280 30.1 4.44 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 41.43 1 36 36 231 4.317E9 201.97 39.98 34 113 15189.11 41.43 35 118 1033 114.3 4.45 HVO_2454 anthranilate synthase component I 41.22 1 16 16 63 1.181E9 73.20 41.22 16 31 4881.67 41.22 16 32 524 55.9 4.56 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 41.13 1 18 18 122 2.077E9 91.52 41.13 18 60 6694.01 41.13 18 62 496 55.0 4.53 HVO_1481 UspA domain protein 41.10 1 5 5 29 1.042E9 30.43 41.10 5 15 1881.37 41.10 5 14 163 17.7 4.40 HVO_0997 peptidase M24 family protein 41.03 1 9 9 25 3.202E8 19.08 30.16 7 11 1258.07 41.03 9 14 368 39.9 4.49 HVO_A0406 conserved hypothetical protein 40.99 1 2 12 47 9.257E8 25.16 38.52 10 23 2388.93 36.79 11 24 405 44.4 5.30 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 40.89 1 15 15 59 4.789E8 47.14 35.66 14 29 3351.20 40.89 15 30 516 56.7 4.89 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 40.77 1 8 8 25 2.558E8 23.89 40.77 8 12 1672.74 40.77 8 13 287 31.8 4.93 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 40.72 1 5 5 50 1.746E9 44.98 29.90 4 21 4319.31 40.72 5 29 194 20.7 4.12 HVO_0024 thiosulfate sulfurtransferase 40.70 1 8 8 46 1.335E9 36.69 36.05 7 22 3023.20 40.70 8 24 258 28.4 4.30 HVO_2256 DUF262 family protein 40.69 1 17 18 63 6.388E8 35.81 30.09 15 30 3354.97 40.69 18 33 462 54.9 4.89 HVO_0787 indole-3-glycerol-phosphate synthase 40.64 1 6 6 14 1.283E8 6.23 40.64 6 7 481.70 40.64 6 7 251 26.7 4.44 HVO_0046 putative glutamate--argW ligase 40.55 1 9 9 48 9.528E8 38.98 40.55 9 23 3053.97 40.55 9 25 291 31.9 4.87 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 40.55 1 17 17 79 1.704E9 61.84 40.55 17 40 4448.14 40.55 17 39 471 51.0 4.48 HVO_2708 YfiH family protein 40.37 1 8 8 36 1.244E9 24.69 40.37 8 19 2159.87 40.37 8 17 322 35.4 4.35 HVO_1577 conserved hypothetical protein 40.11 1 6 6 25 5.650E8 27.36 40.11 6 12 1702.80 40.11 6 13 177 19.4 4.74 HVO_1545 dihydroxyacetone kinase subunit DhaL 40.09 1 8 8 49 1.709E9 33.57 39.66 7 24 2883.52 40.09 8 25 232 24.8 4.48 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 14 8.818E8 15.61 40.00 4 7 1115.01 40.00 4 7 130 14.1 4.79 HVO_0314 A-type ATP synthase subunit C 39.94 1 12 12 45 1.064E9 33.74 35.92 11 22 3079.96 39.94 12 23 348 38.7 4.50 HVO_1854 histidine--tRNA ligase 39.91 1 15 15 74 1.384E9 71.13 39.91 15 37 4794.62 39.91 15 37 431 47.1 4.37 HVO_2156 UspA domain protein 39.87 1 8 8 32 1.027E9 28.07 39.87 8 16 2096.75 39.87 8 16 301 31.6 4.69 HVO_1212 KaiC-type circadian regulator CirA 39.84 1 9 9 49 2.555E9 52.28 37.80 8 23 3812.53 39.84 9 26 246 27.5 4.45 HVO_2981 uracil phosphoribosyltransferase 39.82 1 8 8 41 2.544E9 32.01 32.30 7 18 2844.83 39.82 8 23 226 24.5 4.49 HVO_C0069 GFO family oxidoreductase 39.81 1 11 11 68 5.893E8 57.09 39.81 11 35 3275.42 39.81 11 33 324 36.0 5.10 HVO_0316 A-type ATP synthase subunit A 39.76 1 17 17 123 6.563E9 124.11 39.76 17 62 8472.19 39.76 17 61 586 64.5 4.25 HVO_1091 proteasome alpha subunit 39.68 1 8 9 44 2.123E9 49.67 39.68 9 22 3297.27 39.68 9 22 252 27.6 4.56 HVO_1973 conserved hypothetical protein 39.52 1 4 4 22 2.809E8 15.42 39.52 4 11 1246.48 37.72 3 11 167 18.1 4.36 HVO_0353 30S ribosomal protein S12 39.44 1 7 7 35 1.078E9 35.50 39.44 7 17 2324.35 39.44 7 18 142 15.5 9.91 HVO_1080 conserved hypothetical protein 39.36 1 6 6 28 4.963E8 20.85 39.36 6 15 1090.12 38.83 5 13 188 21.1 4.31 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 39.32 1 10 10 53 8.092E8 37.99 39.32 10 27 2333.89 35.31 9 26 473 50.8 4.58 HVO_1198 UspA domain protein 39.31 1 5 5 20 1.217E9 23.89 39.31 5 10 1528.36 39.31 5 10 145 15.6 4.75 HVO_2057 sugar nucleotidyltransferase 39.22 1 12 12 79 2.769E9 77.93 39.22 12 39 5253.00 39.22 12 40 357 37.8 4.44 HVO_1901 translation initiation factor aIF-2 gamma subunit 39.17 1 12 12 74 3.178E9 52.62 39.17 12 36 3922.87 39.17 12 38 411 43.9 4.36 HVO_2547 50S ribosomal protein L32e 39.15 1 5 5 18 2.398E8 14.48 18.72 3 8 1173.68 39.15 5 10 235 25.8 4.75 HVO_1327 AAA-type ATPase (CDC48 subfamily) 39.13 1 18 19 68 5.555E8 35.58 34.38 17 34 3080.96 39.13 19 34 736 78.1 4.88 HVO_1391 NUDIX family hydrolase 39.07 1 5 5 12 6.435E7 6.67 39.07 5 6 677.48 39.07 5 6 151 17.4 5.01 HVO_2781 DNA-directed RNA polymerase subunit D 39.00 1 6 6 33 1.523E9 27.17 39.00 6 17 2101.45 39.00 6 16 259 28.1 4.32 HVO_1654 cysteine synthase 38.89 1 8 8 22 5.161E8 14.26 33.99 7 11 1096.74 33.33 7 11 306 32.3 4.32 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 38.85 1 10 10 64 4.333E9 60.30 34.48 9 31 4004.64 38.85 10 33 435 46.9 4.63 HVO_0349 DNA-directed RNA polymerase subunit A' 38.73 1 29 29 208 2.842E9 192.16 38.73 29 102 14193.46 38.73 29 106 976 108.8 4.81 HVO_0109 cysteine desulfurase 38.73 1 13 13 66 1.150E9 66.83 36.85 12 32 4713.63 38.73 13 34 426 46.8 4.56 HVO_1590 DnaK-type molecular chaperone Hsp70 38.72 1 20 20 176 6.995E9 168.40 38.72 20 87 10775.23 38.72 20 89 625 67.2 4.18 HVO_0321 peptide chain release factor aRF-1 38.65 1 15 15 54 6.553E8 28.16 31.64 14 27 2790.09 35.27 14 27 414 46.6 4.83 HVO_2682 dodecin 38.57 1 2 2 8 2.546E8 9.96 38.57 2 4 540.62 38.57 2 4 70 7.7 4.22 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 38.51 1 13 13 74 1.441E9 84.79 35.92 12 36 4918.87 38.51 13 38 348 38.2 4.32 HVO_0812 phosphoenolpyruvate synthase 38.50 1 25 25 98 9.667E8 103.85 35.74 23 48 6418.28 38.50 25 50 761 83.1 4.63 HVO_0541 aconitate hydratase 38.49 1 23 23 90 2.054E9 57.41 32.20 20 44 4478.89 38.49 23 46 938 102.1 4.40 HVO_0911 GTP-binding protein Drg 38.48 1 11 11 34 2.440E8 24.14 38.48 11 18 1861.42 36.59 10 16 369 40.5 4.81 HVO_1778 catalase-peroxidase 38.44 1 17 17 95 3.857E9 102.72 38.44 16 48 6426.63 38.44 17 47 718 80.0 4.31 HVO_2790 ATP-binding protein Mrp 38.44 1 8 8 36 5.648E8 36.35 38.44 8 18 2203.71 38.44 8 18 346 36.8 4.50 HVO_0806 pyruvate kinase 38.29 1 17 17 107 2.349E9 100.41 38.29 17 53 6563.35 38.29 17 54 585 62.0 4.54 HVO_0358 homoserine dehydrogenase 38.17 1 7 8 37 1.321E9 37.94 38.17 8 19 2375.10 38.17 8 18 317 32.4 4.44 HVO_0536 ferritin 38.07 1 3 3 12 4.548E8 18.84 38.07 3 6 776.09 38.07 3 6 176 19.9 4.50 HVO_2716 acyl-CoA dehydrogenase 38.06 1 11 11 56 7.391E8 57.68 38.06 11 27 4211.51 38.06 11 29 381 41.3 4.65 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 87 2.935E9 83.61 35.50 8 43 5790.24 38.05 9 44 431 46.1 4.48 HVO_2029 Lrp/AsnC family transcription regulator 37.91 1 3 4 13 3.197E8 9.84 26.80 3 5 644.37 37.91 4 8 153 16.9 4.21 HVO_1348 probable YjeF family carbohydrate kinase 37.87 1 13 13 52 3.104E8 42.73 37.87 13 27 2790.07 37.87 12 25 478 48.8 4.45 HVO_0729 inorganic pyrophosphatase 37.85 1 8 8 57 2.104E9 63.16 37.85 6 27 4075.08 37.85 8 30 177 20.4 4.16 HVO_1571 DNA topoisomerase VI subunit B 37.84 1 22 22 101 1.625E9 71.26 34.34 20 48 5434.88 37.84 22 53 798 87.4 4.73 HVO_1573 DNA gyrase subunit A 37.82 1 27 27 130 1.773E9 115.09 36.89 26 64 7557.55 37.24 26 66 862 94.8 4.56 HVO_1374 acyl-CoA synthetase 37.79 1 15 15 76 3.416E9 72.30 32.91 14 37 4137.07 37.79 15 39 553 61.1 4.50 HVO_2227 siroheme decarboxylase AhbA 37.75 1 7 7 20 6.898E8 15.46 37.75 7 10 1135.71 29.97 6 10 347 39.1 4.69 HVO_2883 conserved hypothetical protein 37.75 1 19 19 75 4.003E8 58.19 37.75 19 37 4335.85 37.75 19 38 702 78.9 4.48 HVO_A0092 acyl-CoA dehydrogenase 37.53 1 9 9 37 2.274E8 14.47 37.53 9 18 1293.74 37.53 9 19 381 42.2 4.83 HVO_1134 conserved hypothetical protein 37.52 1 16 16 70 6.956E8 49.98 37.52 16 35 3715.25 37.52 16 35 757 80.6 4.35 HVO_2188 phosphoribosylformylglycinamidine synthase 1 37.50 1 6 6 22 4.412E8 18.84 37.50 6 11 1261.63 37.50 6 11 224 23.9 4.36 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.35 1 12 12 169 4.793E9 102.11 37.35 12 86 7700.13 37.35 12 83 332 34.8 4.22 HVO_2813 RimK family protein 37.31 1 14 14 96 3.086E9 88.04 37.31 14 47 6192.45 37.31 14 49 453 49.0 4.73 HVO_0466 citrate (si)-synthase 37.20 1 12 12 82 3.364E9 96.42 37.20 12 41 5928.11 37.20 12 41 379 41.8 4.55 HVO_0717 "cell division protein FtsZ, type I" 37.20 1 11 11 79 5.772E9 83.38 37.20 11 39 5570.91 37.20 11 40 379 39.8 4.40 HVO_1076 sugar nucleotidyltransferase 36.96 1 8 8 40 1.849E9 46.91 36.96 8 19 3071.64 36.96 8 21 322 35.8 4.20 HVO_1387 enoyl-CoA hydratase 36.96 1 7 7 29 5.705E8 12.13 32.30 6 14 1273.83 36.96 7 15 257 27.5 4.51 HVO_0388 homolog to ribonuclease R 36.90 1 16 16 83 1.225E9 75.74 36.90 15 41 5097.38 36.90 16 42 439 50.3 4.73 HVO_2436 malic enzyme (NADP) 36.75 1 17 20 133 1.747E9 123.53 36.75 20 66 8621.04 36.75 20 67 751 81.4 4.55 HVO_1553 hydroxypyruvate reductase 36.65 1 11 11 43 6.241E8 30.62 36.65 11 22 2499.45 30.54 10 21 442 45.2 4.50 HVO_2168 AAA-type ATPase (MoxR subfamily) 36.47 1 9 9 33 3.272E8 18.11 33.74 8 16 1567.23 36.47 9 17 329 35.9 4.54 HVO_0041 ornithine carbamoyltransferase 36.45 1 7 7 38 7.259E8 15.37 36.45 7 20 1614.24 36.45 7 18 299 32.7 4.37 HVO_1300 triosephosphate isomerase 36.45 1 4 4 30 2.786E9 28.98 36.45 4 16 2004.88 36.45 4 14 214 21.3 4.26 HVO_0350 DNA-directed RNA polymerase subunit A'' 36.28 1 14 14 70 3.605E9 66.88 30.79 13 36 4212.76 35.08 13 34 419 46.1 4.35 HVO_0417 metal-dependent carboxypeptidase 36.25 1 15 15 62 1.116E9 58.26 32.87 14 30 4184.06 36.06 14 32 502 57.3 4.42 HVO_1575 arginase 36.12 1 6 6 21 3.429E8 12.80 36.12 6 10 796.10 36.12 6 11 299 31.0 4.58 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 36.01 1 7 7 39 1.193E9 41.13 36.01 7 19 2887.93 36.01 7 20 336 36.0 4.51 HVO_A0331 D-galactonate dehydratase 35.94 1 7 7 31 4.808E8 25.67 35.94 7 16 1635.96 35.94 7 15 384 42.8 4.83 HVO_1291 fumarylacetoacetase family protein 35.80 1 4 4 13 1.039E9 12.02 20.99 3 6 842.40 35.80 4 7 243 26.3 4.55 HVO_1508 acetolactate synthase large subunit 35.78 1 12 12 57 1.543E9 59.13 35.78 12 29 3709.94 35.78 12 28 587 62.3 4.36 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 35.51 1 32 32 157 1.865E9 103.39 35.51 32 77 7720.88 35.51 32 80 1284 141.2 4.35 HVO_0879 DUF371 family protein 35.46 1 2 2 2 7.963E7 2.67 35.46 2 2 141 15.3 4.65 HVO_0661 dCTP deaminase (dUMP-forming) 35.38 1 6 6 25 2.492E8 16.10 35.38 6 13 1118.42 34.36 5 12 195 21.2 4.59 HVO_2040 NAD-dependent epimerase/dehydratase 35.29 1 5 9 60 2.605E9 51.35 35.29 9 30 3590.60 35.29 9 30 306 33.8 4.51 HVO_A0205 CRISPR-associated endoribonuclease Cas6 35.29 1 8 8 44 9.769E8 36.71 35.29 8 22 2931.57 35.29 8 22 272 31.0 5.44 HVO_0874 beta-lactamase domain protein 35.16 1 19 19 100 2.822E9 80.36 35.16 18 48 6476.24 35.16 19 52 640 71.9 5.14 HVO_1867 lysine--tRNA ligase 35.14 1 16 16 61 6.033E8 44.35 35.14 16 30 2951.18 34.05 15 31 555 62.1 4.46 HVO_1593 PAC2 family protein 35.08 1 4 4 21 5.419E8 18.73 35.08 4 11 1109.68 35.08 4 10 248 26.6 4.46 HVO_0138 tyrosine--tRNA ligase 35.06 1 7 7 49 1.531E9 20.49 35.06 7 24 2243.01 35.06 7 25 328 36.1 4.34 HVO_B0149 oleate hydratase 34.90 1 12 13 44 7.712E8 20.39 32.46 12 22 2391.63 32.46 12 22 533 60.1 4.64 HVO_1306 chorismate synthase 34.81 1 9 9 47 4.836E8 44.73 34.81 9 23 2968.58 34.81 9 24 385 41.9 4.83 HVO_2706 translation initiation factor aIF-2B delta subunit 34.75 1 7 7 37 1.169E9 30.43 34.75 7 18 1918.60 34.75 7 19 282 30.7 4.42 HVO_2759 peptidase M42 family protein 34.75 1 9 9 41 9.191E8 48.82 34.75 9 21 3036.60 34.75 9 20 354 37.0 4.40 HVO_1025 acetyl-CoA C-acyltransferase 34.73 1 9 9 50 1.158E9 53.96 34.73 9 25 3650.16 34.73 9 25 383 40.7 4.56 HVO_1896 30S ribosomal protein S24e 34.65 1 3 3 13 3.618E7 9.63 34.65 3 7 752.30 34.65 3 6 101 11.6 4.68 HVO_1125 cysteine--tRNA ligase 34.62 1 12 12 51 8.773E8 40.11 34.62 12 26 3063.30 34.62 12 25 494 55.2 4.56 HVO_0118 50S ribosomal protein L20e 34.48 1 2 2 4 2.378E8 2.84 34.48 2 4 58 6.4 6.52 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 34.45 1 4 4 11 3.778E8 2.37 34.45 4 6 371.21 34.45 4 5 238 24.7 4.15 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 34.44 1 10 10 44 4.170E8 36.67 34.44 10 22 3063.80 34.44 10 22 363 39.3 4.97 HVO_1531 UDP-glucose 6-dehydrogenase 34.42 1 14 14 59 7.787E8 48.85 34.42 14 30 3616.28 34.42 14 29 430 45.9 4.50 HVO_2740 nucleoside-diphosphate kinase 34.42 1 4 4 29 2.365E8 25.60 34.42 4 16 1587.83 34.42 4 13 154 17.5 4.50 HVO_0552 DNA mismatch repair protein MutS 34.20 1 23 23 88 5.265E8 72.65 32.79 22 43 5016.60 34.20 23 45 924 99.2 4.65 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 33.98 1 10 10 75 1.949E9 41.06 30.12 9 35 5066.02 33.98 10 40 259 29.9 4.36 HVO_1123 thioredoxin-disulfide reductase 33.81 1 9 9 44 1.823E9 34.29 30.66 8 19 3050.30 33.81 9 25 349 37.3 4.32 HVO_B0059 cobalt-precorrin 5A hydrolase 33.74 1 8 8 47 1.545E9 51.09 33.74 8 24 3168.43 33.74 8 23 326 34.5 4.51 HVO_B0114 IclR family transcription regulator 33.73 1 9 9 31 2.365E8 17.52 33.73 9 16 1469.15 33.73 9 15 252 28.4 5.44 HVO_0511 NAD-dependent epimerase/dehydratase 33.59 1 5 5 30 3.080E8 14.68 33.59 5 14 1403.57 33.59 5 16 262 29.3 4.78 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 33.51 1 4 4 34 8.798E8 13.15 33.51 4 17 1239.31 33.51 4 17 188 20.5 4.60 HVO_1572 DNA gyrase subunit B 33.49 1 20 20 96 9.611E8 68.64 33.49 20 49 5751.92 32.71 19 47 639 71.2 4.83 HVO_1660 DisA-N domain protein 33.46 1 7 7 26 7.750E8 33.77 33.46 7 13 2033.43 33.46 7 13 269 28.9 4.73 HVO_0292 replication protein A 33.44 1 9 9 40 8.746E8 35.65 33.44 9 20 2637.20 33.44 9 20 311 34.6 4.31 HVO_2675 histidinol dehydrogenase 33.41 1 9 9 43 8.359E8 47.00 33.41 9 21 3008.25 33.41 9 22 428 45.4 4.50 HVO_1172 NAD-dependent epimerase/dehydratase 33.33 1 8 8 34 3.285E9 26.86 33.33 8 16 2248.75 33.33 8 18 315 34.9 4.34 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 33.33 1 7 7 30 2.120E9 24.98 33.33 7 15 1847.66 33.33 7 15 252 26.0 4.39 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 33.26 1 10 10 35 7.985E8 14.58 31.15 9 17 1871.27 33.26 10 18 427 45.4 4.56 HVO_0601 homoserine dehydrogenase 33.23 1 5 6 32 9.876E8 37.50 33.23 6 16 2163.81 33.23 6 16 316 32.2 4.25 HVO_1459 ThuA family protein 33.19 1 4 4 21 5.920E8 13.44 33.19 4 10 1163.94 33.19 4 11 238 26.8 4.67 HVO_1250 redoxin domain protein 33.16 1 3 3 5 1.544E8 734.92 33.16 3 5 187 20.5 4.03 HVO_0484 50S ribosomal protein L10e 32.95 1 5 5 20 1.468E8 16.18 32.95 5 10 835.14 32.95 5 10 176 19.8 8.72 HVO_0401 UspA domain protein 32.89 1 4 4 19 8.598E8 14.73 32.89 4 9 1105.61 32.89 4 10 152 16.4 4.79 HVO_1370 gamma-glutamyl phosphate reductase 32.88 1 12 12 68 1.836E9 48.17 32.88 12 35 3356.00 32.88 12 33 444 48.1 4.34 HVO_1018 RecJ domain protein 32.86 1 21 21 118 2.301E9 103.52 32.86 21 60 7646.57 32.86 21 58 633 69.8 4.58 HVO_2348 GTP cyclohydrolase MptA 32.79 1 8 8 38 8.427E8 30.69 32.79 8 19 1474.39 32.79 8 19 308 33.5 4.68 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 32.74 1 7 7 46 1.139E9 39.54 32.74 7 23 3074.52 32.74 7 23 226 25.5 4.25 HVO_1625 conserved hypothetical protein 32.72 1 14 14 47 6.300E8 38.82 30.73 13 24 2650.72 22.32 12 23 654 70.1 4.04 HVO_1547 isoleucine--tRNA ligase 32.69 1 22 22 150 1.759E9 124.51 32.69 22 72 8042.09 32.69 22 78 1043 117.9 4.30 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 32.67 1 5 5 14 1.901E8 5.96 32.67 5 7 420.45 32.67 5 7 202 22.2 5.11 HVO_B0111 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 32.67 1 10 10 41 3.588E8 12.99 27.43 9 19 1456.57 32.67 10 22 401 44.2 4.54 HVO_2643 NADPH:quinone reductase 32.66 1 7 7 55 9.811E8 49.61 32.66 7 27 3621.32 32.66 7 28 346 37.2 4.55 HVO_1332 conserved hypothetical protein 32.56 1 3 3 7 2.772E8 6.16 16.28 2 3 608.77 32.56 3 4 129 14.9 4.16 HVO_2205 arNOG06768 family NADH-binding domain protein 32.56 1 7 7 26 2.460E8 24.61 32.56 7 13 1449.13 32.56 7 13 301 32.0 5.00 HVO_1465 naphthoate synthase 32.46 1 7 7 25 2.491E8 20.99 29.51 6 12 1235.50 32.46 7 13 305 33.9 4.83 HVO_0470 threonine synthase 32.43 1 6 6 13 1.258E8 4.33 12.53 3 5 461.74 32.43 6 8 367 39.2 4.59 HVO_2717 alanine--tRNA ligase 32.41 1 9 9 39 3.720E8 40.37 29.40 8 18 2534.78 32.41 9 21 398 41.6 4.39 HVO_1371 glutamate 5-kinase 32.23 1 6 6 17 5.639E8 15.25 32.23 6 8 1301.03 32.23 6 9 301 32.0 4.25 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 32.17 1 9 9 42 1.832E9 21.20 32.17 9 21 2296.81 32.17 9 21 373 40.2 4.44 HVO_2333 conserved hypothetical protein 32.14 1 7 7 18 2.394E8 8.22 32.14 7 9 793.18 32.14 7 9 308 34.9 4.54 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 32.10 1 14 15 85 8.236E8 79.05 32.10 15 43 4684.65 32.10 15 42 623 62.1 5.30 HVO_1576 NAD-dependent epimerase/dehydratase 32.03 1 5 9 46 1.809E9 39.60 32.03 9 23 3135.79 32.03 9 23 306 33.9 4.51 HVO_3007 malate dehydrogenase 31.91 1 11 11 202 1.043E10 209.93 31.91 11 102 10661.48 31.91 11 100 304 32.6 4.40 HVO_0681 DNA topoisomerase I 31.90 1 19 19 61 4.871E8 45.78 31.90 19 33 3058.29 28.69 18 28 840 93.6 4.58 HVO_0549 2-keto-3-deoxygluconate kinase 31.87 1 8 9 34 7.738E8 12.66 28.13 8 16 1754.39 31.87 9 18 320 34.1 4.34 HVO_0406 RNA-binding protein AU-1 31.84 1 10 10 30 1.797E9 27.59 31.84 10 16 1596.01 31.84 10 14 468 49.9 4.53 HVO_0122 phosphoglycerate dehydrogenase 31.79 1 6 6 25 3.913E8 31.45 24.69 5 12 1584.86 31.79 6 13 324 35.3 5.35 HVO_A0266 IclR family transcription regulator 31.76 1 7 7 33 2.319E8 27.98 29.02 6 16 1929.02 31.76 7 17 255 27.7 6.05 HVO_0658 tRNA pseudouridine(13) synthase TruD 31.75 1 9 9 26 2.784E8 13.49 21.38 7 12 992.78 28.94 8 14 463 50.6 4.70 HVO_2712 3'-5' RNA ligase 31.69 1 12 12 49 5.699E8 24.96 31.69 12 24 2529.27 29.63 11 25 486 53.4 4.92 HVO_2861 conserved hypothetical protein 31.64 1 9 9 53 1.577E9 59.66 31.64 9 27 3267.37 28.36 8 26 275 29.1 4.27 HVO_2555 30S ribosomal protein S17 31.58 1 2 2 2 7.464E7 48.04 31.58 2 2 114 12.7 4.81 HVO_1020 HEAT-PBS family protein 31.50 1 8 8 30 6.218E8 31.77 22.67 6 13 2583.35 31.50 8 17 419 45.5 3.95 HVO_B0061 precorrin-2 C20-methyltransferase 31.49 1 6 6 26 6.056E8 15.43 23.83 5 12 1710.33 31.49 6 14 235 25.3 4.63 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 31.48 1 8 8 27 6.370E8 23.39 29.26 7 13 1622.43 31.48 8 14 270 29.1 4.35 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 18 1.856E9 14.36 31.45 3 9 1187.47 31.45 3 9 124 14.2 5.22 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 31.45 1 7 7 18 2.376E8 10.04 19.88 6 9 793.58 31.45 7 9 337 35.9 4.69 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 31.44 1 9 9 26 1.946E8 22.20 31.44 9 13 1325.99 31.44 9 13 439 47.2 4.59 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 31.35 1 12 12 89 2.896E9 74.60 29.19 11 44 5309.64 31.35 12 45 370 41.9 4.48 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 31.30 1 8 8 27 3.213E8 23.57 31.30 8 13 1735.43 29.86 7 14 345 36.9 4.68 HVO_0123 signal recognition particle 54K protein 31.18 1 11 11 36 7.623E8 32.46 29.03 10 18 2289.74 30.97 10 18 465 50.9 4.50 HVO_A0432 conserved hypothetical protein 31.11 1 0 10 38 8.139E8 22.80 28.64 8 18 2148.12 31.11 10 20 405 44.5 5.24 HVO_1079 sulfate adenylyltransferase small subunit 31.08 1 7 7 28 7.870E8 23.21 31.08 7 14 1817.19 31.08 7 14 325 37.5 4.18 HVO_2721 amidophosphoribosyltransferase 31.03 1 8 8 41 1.390E9 42.42 31.03 8 21 2582.90 31.03 8 20 493 53.4 4.78 HVO_B0018 ParA domain protein 31.01 1 5 5 28 2.899E8 20.14 31.01 5 13 1204.50 31.01 5 15 287 31.7 4.74 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 30.99 1 10 10 55 1.670E9 41.81 30.99 10 28 2737.11 29.28 9 27 526 57.2 4.31 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 30.88 1 16 16 72 9.700E8 61.69 28.47 15 34 4996.25 30.88 16 38 706 73.3 4.39 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 40 1.214E9 34.90 30.84 8 20 2475.80 30.84 8 20 415 44.4 4.41 HVO_A0256 conserved hypothetical protein 30.84 1 2 2 2 5.713E7 34.87 30.84 2 2 107 12.4 4.68 HVO_1957 proteasome-activating nucleotidase 30.83 1 8 8 34 2.529E8 20.86 30.83 8 16 1616.08 30.83 8 18 412 45.6 4.48 17318569 keratin 1 [Homo sapiens] 30.75 1 1 19 109 1.646E9 104.33 28.88 18 54 7357.49 30.75 19 55 644 66.0 8.12 HVO_0017 conserved hypothetical protein 30.73 1 3 3 10 2.726E8 4.55 30.73 3 5 520.45 30.73 3 5 192 21.9 4.50 HVO_1311 probable oxidoreductase (short-chain dehydrogenase family) 30.60 1 9 9 37 7.168E8 27.09 27.05 8 18 1936.72 30.60 9 19 281 30.1 4.46 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 30.47 1 4 4 14 2.322E8 11.45 30.47 4 7 984.15 30.47 4 7 128 13.0 4.31 HVO_1496 phosphotransferase system component I 30.27 1 13 13 82 1.056E9 71.75 30.27 13 42 5557.86 30.27 13 40 565 60.3 4.21 HVO_1967 glucose-6-phosphate isomerase 30.23 1 10 10 33 5.263E8 26.65 30.23 10 16 1956.95 30.23 10 17 430 45.6 4.40 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 30.22 1 10 10 64 7.560E8 55.56 30.22 10 31 4025.67 30.22 10 33 364 39.3 4.35 HVO_1880 conserved hypothetical protein 30.22 1 6 6 26 8.956E7 18.32 30.22 6 13 1363.25 30.22 6 13 225 23.8 4.59 HVO_C0001 Orc1-type DNA replication protein 30.15 1 10 10 31 2.842E8 18.58 22.79 9 15 1451.44 30.15 10 16 408 45.2 4.97 HVO_1150 IS200-type transposase 30.00 1 3 3 7 1.331E8 2.09 30.00 3 4 230.02 25.38 2 3 130 14.7 5.49 HVO_2773 30S ribosomal protein S2 30.00 1 4 4 35 5.045E9 44.60 30.00 4 18 2866.34 30.00 4 17 260 28.3 4.16 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 29.93 1 14 14 62 1.187E9 42.52 29.93 14 31 3655.41 29.93 14 31 461 50.7 4.73 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 29.75 1 9 9 59 1.116E9 35.47 29.75 9 29 3303.11 29.75 9 30 447 48.5 4.56 HVO_1478 transcription initiation factor TFB 29.65 1 5 9 49 1.087E9 37.00 29.65 9 24 2985.22 29.65 9 25 317 35.7 5.47 HVO_2913 superoxide dismutase (Mn) 29.65 1 0 3 19 3.789E9 19.15 29.65 3 9 1399.96 29.65 3 10 199 22.3 4.48 HVO_B0371 aldehyde dehydrogenase 29.64 1 7 7 31 3.963E8 27.81 29.64 7 15 1217.03 29.64 7 16 496 52.5 4.39 HVO_A0288 probable oxidoreductase (short-chain dehydrogenase family) 29.64 1 7 7 29 3.277E8 19.90 27.50 6 14 1377.41 29.64 7 15 280 29.9 4.74 HVO_1164 HD family hydrolase 29.63 1 7 7 38 7.490E8 32.71 29.63 7 19 2367.68 29.63 7 19 270 29.8 4.87 HVO_2425 GNAT family acetyltransferase 29.63 1 5 5 18 7.821E8 13.84 29.63 5 9 950.51 29.63 5 9 216 24.4 4.54 HVO_1500 1-phosphofructokinase 29.51 1 5 5 14 2.364E8 3.63 22.95 4 7 486.82 29.51 5 7 305 32.0 4.51 HVO_A0475 superoxide dismutase (Mn) 29.50 1 0 3 19 3.789E9 19.15 29.50 3 9 1399.96 29.50 3 10 200 22.4 4.45 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 29.41 1 9 9 29 3.470E8 15.55 23.76 8 15 1476.12 29.41 9 14 442 46.9 4.58 HVO_1847 oligoendopeptidase PepF 29.38 1 13 13 56 5.463E8 54.46 29.38 13 28 3360.51 29.38 13 28 599 68.5 4.41 HVO_1816 dihydroorotase 29.37 1 9 9 35 2.707E8 25.10 29.37 9 18 1815.49 29.37 9 17 429 45.4 4.40 HVO_A0551 acyl-CoA synthetase 29.37 1 14 14 56 1.544E9 49.97 29.37 14 28 3625.63 27.88 13 28 538 59.6 4.65 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 29.35 1 0 18 107 1.646E9 102.13 27.48 17 53 7214.36 29.35 18 54 644 66.0 8.12 HVO_0100 NMD3 family protein 29.33 1 7 7 22 2.044E8 18.17 29.33 7 11 1192.28 29.33 7 11 375 41.6 4.46 HVO_A0496 UspA domain protein 29.31 1 7 7 33 9.935E8 25.08 29.31 7 17 1961.00 29.31 7 16 290 31.4 4.60 HVO_2688 TrmB family transcription regulator 29.18 1 8 8 29 1.807E9 33.84 27.48 7 14 2574.45 29.18 8 15 353 39.3 4.58 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 28.98 1 21 21 95 1.769E9 52.90 27.83 20 46 5269.76 28.98 21 49 697 74.5 4.13 HVO_2380 AAA-type ATPase (CDC48 subfamily) 28.94 1 16 16 50 4.315E8 34.06 28.94 16 25 2297.65 27.59 15 25 743 81.9 4.82 HVO_B0060 precorrin-4 C11-methyltransferase 28.67 1 4 4 18 4.636E8 7.00 28.67 4 9 671.26 28.67 4 9 279 29.7 4.22 HVO_2793 conserved hypothetical protein 28.57 1 4 4 12 1.387E8 9.83 28.57 4 6 602.41 28.57 4 6 252 27.1 4.46 HVO_1236 acyl-CoA synthetase 28.41 1 12 12 46 1.052E9 30.91 28.41 12 22 2339.73 28.41 12 24 535 59.1 4.60 HVO_1380 methylmalonyl-CoA mutase subunit A 28.32 1 11 11 53 5.347E8 45.12 28.32 11 26 3005.24 28.32 11 27 558 61.9 4.41 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 28.30 1 6 6 21 4.277E8 18.77 28.30 6 10 1230.70 28.30 6 11 265 29.3 4.92 HVO_0868 NAD-dependent epimerase/dehydratase 28.27 1 6 6 16 9.831E7 2.40 22.80 5 8 545.31 28.27 6 8 329 36.1 4.55 HVO_1295 histidinol-phosphate aminotransferase 28.25 1 7 8 25 8.174E8 18.88 28.25 8 13 1414.59 26.32 7 12 361 39.4 4.51 HVO_0831 ArgK-type transport ATPase 28.23 1 7 7 17 2.252E8 11.62 21.24 6 8 944.46 28.23 7 9 372 39.6 4.65 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 28.20 1 6 6 30 2.888E8 18.22 24.71 5 15 1836.29 17.44 5 15 344 37.0 4.55 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 28.13 1 7 7 24 3.835E8 20.98 28.13 7 12 1548.33 28.13 7 12 327 36.2 4.63 40354192 keratin 10 [Homo sapiens] 28.08 1 0 16 54 7.248E8 46.96 28.08 16 28 2787.26 27.74 15 26 584 58.8 5.16 HVO_2947 phenylalanine--tRNA ligase beta subunit 28.07 1 13 13 57 1.459E9 56.10 24.21 10 26 4713.10 28.07 13 31 570 63.3 4.46 HVO_0357 ACT domain protein 28.04 1 5 5 19 8.747E8 13.74 28.04 5 10 945.67 28.04 5 9 189 20.2 4.59 HVO_2960 dihydrolipoamide S-acyltransferase 28.02 1 12 12 51 6.865E8 48.21 28.02 12 25 3401.17 28.02 12 26 521 54.9 4.40 HVO_1527 glucose-1-phosphate uridylyltransferase 27.98 1 8 8 35 8.142E8 25.04 27.98 8 16 1862.86 27.98 8 19 243 27.5 4.70 HVO_2467 NADPH:quinone reductase 27.73 1 6 6 28 6.118E8 19.70 27.73 6 14 1680.13 27.73 6 14 321 33.0 4.51 HVO_1491 HAD superfamily hydrolase 27.70 1 8 8 35 3.366E8 35.24 27.70 8 18 2081.18 24.75 7 17 408 44.4 4.60 HVO_2417 conserved hypothetical protein 27.69 1 3 3 17 5.831E8 17.91 27.69 3 8 1426.19 27.69 3 9 195 21.6 3.65 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 27.67 1 5 5 26 9.117E8 18.16 27.67 5 13 1524.79 27.67 5 13 253 26.0 4.60 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 27.66 1 0 16 54 7.248E8 46.96 27.66 16 28 2787.26 27.32 15 26 593 59.5 5.21 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 27.62 1 8 8 21 2.988E8 13.56 24.42 7 10 1360.93 27.62 8 11 344 39.1 4.73 HVO_2239 UspA domain protein 27.46 1 5 5 16 6.502E8 11.99 27.46 5 8 892.35 27.46 5 8 142 15.4 4.16 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 27.43 1 7 7 28 1.397E9 22.20 27.43 7 14 1605.30 27.43 7 14 339 38.1 4.50 HVO_2918 thymidylate synthase 27.41 1 5 5 18 2.560E8 12.23 27.41 5 9 969.64 27.41 5 9 332 37.5 4.61 HVO_0893 methylmalonyl-CoA mutase subunit A 27.39 1 11 11 43 1.159E9 40.64 27.39 11 21 2468.24 27.39 11 22 566 63.1 4.36 HVO_2580 L-aspartate oxidase 27.37 1 11 11 49 5.912E8 38.53 27.37 11 25 3380.41 27.37 11 24 537 55.8 4.63 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 27.32 1 5 5 23 5.878E8 13.30 27.32 5 11 1016.45 27.32 5 12 377 39.2 4.18 HVO_1783 conserved hypothetical protein 27.23 1 4 4 12 9.931E7 9.23 27.23 4 6 545.06 27.23 4 6 224 24.1 5.90 HVO_0745 "FtsZ family protein, type III" 27.22 1 6 6 19 1.862E8 15.47 27.22 6 9 1186.55 27.22 6 10 360 37.1 4.51 HVO_0429 archaemetzincin 27.17 1 3 3 8 1.257E8 4.42 27.17 3 4 426.44 27.17 3 4 173 19.3 6.54 HVO_0573 endonuclease IV 27.15 1 5 5 30 1.432E9 27.87 27.15 5 15 1898.10 27.15 5 15 291 31.4 4.44 HVO_1871 UPF0447 family protein 27.15 1 11 11 72 1.159E9 49.96 23.75 10 34 3934.66 27.15 11 38 501 56.1 4.59 HVO_1460 enoyl-CoA hydratase 27.14 1 5 5 18 1.970E8 9.66 27.14 5 9 731.77 27.14 5 9 269 28.2 4.49 HVO_1337 rpa-associated protein 26.97 1 9 9 43 1.634E9 30.94 26.97 9 21 2227.77 21.03 8 22 623 64.8 3.68 HVO_1683 4-alpha-glucanotransferase 26.81 1 11 11 34 3.394E8 17.80 19.76 9 16 1503.63 26.81 11 18 496 56.3 4.45 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 26.80 1 8 8 47 1.208E9 46.55 20.46 6 23 2784.21 26.80 8 24 347 36.8 4.93 HVO_1097 diaminopimelate epimerase 26.74 1 5 5 16 1.329E8 17.97 23.26 4 8 1036.31 18.75 4 8 288 29.9 4.48 HVO_0087 porphobilinogen synthase 26.61 1 7 7 28 3.741E8 30.07 26.61 7 14 1508.99 26.61 7 14 327 35.3 4.72 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 26.56 1 5 5 18 2.055E8 18.99 26.56 5 9 1056.10 26.56 5 9 305 34.1 4.91 HVO_1488 D-gluconate dehydratase 26.46 1 7 9 72 1.816E9 56.44 26.46 9 37 4662.18 26.46 9 35 412 45.8 4.60 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 26.43 1 7 7 27 3.553E8 32.23 26.43 7 13 2154.80 26.43 7 14 333 36.7 4.56 HVO_C0042 helicase domain protein 26.37 1 29 29 100 1.226E9 81.49 25.82 28 51 5462.39 25.82 28 49 1274 144.4 4.67 HVO_1175 DUF2110 family protein 26.22 1 4 4 22 1.492E9 34.13 26.22 4 11 1937.15 26.22 4 11 225 24.4 4.63 HVO_0452 leucine--tRNA ligase 26.20 1 20 20 82 8.376E8 65.02 26.20 20 41 5172.39 23.38 19 41 958 109.5 4.37 HVO_2008 archaeosine synthase 26.15 1 11 11 36 9.078E8 22.96 24.62 10 18 1951.87 26.15 11 18 585 64.9 4.81 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 8 1.523E8 6.77 26.15 3 4 502.42 26.15 3 4 130 13.4 8.56 HVO_0048 argininosuccinate lyase 26.02 1 9 9 32 3.484E8 33.21 23.77 8 16 2404.06 23.98 8 16 488 50.8 4.53 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 25.97 1 21 21 117 1.395E9 122.56 25.97 21 59 7670.89 25.97 21 58 1082 117.2 4.32 HVO_2496 adenylate kinase 25.96 1 4 4 20 1.156E9 24.90 25.96 4 10 1440.60 25.96 4 10 208 23.1 4.25 HVO_2536 CHP00300 family protein 25.96 1 5 5 17 4.280E8 7.33 25.96 5 8 557.19 25.96 5 9 416 44.8 4.51 HVO_A0087 fumarylacetoacetase family protein 25.95 1 6 6 18 8.007E8 28.66 17.65 4 8 1715.73 25.95 6 10 289 32.0 4.21 HVO_B0040 IclR family transcription regulator 25.90 1 6 6 20 1.783E8 20.15 22.31 5 9 1391.14 25.90 6 11 251 27.2 5.30 HVO_0519 replication protein A 25.88 1 9 9 44 1.052E9 23.26 25.88 9 22 2448.40 25.88 9 22 483 51.0 4.13 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 25.84 1 4 5 14 7.494E8 8.90 22.85 4 6 849.83 25.84 5 8 267 29.1 4.63 HVO_2383 DNA repair and recombination protein RadB 25.76 1 4 4 11 1.259E8 13.32 18.78 3 5 690.78 25.76 4 6 229 24.6 5.02 HVO_0867 HD family hydrolase 25.65 1 5 5 17 1.833E8 6.87 25.65 5 8 739.61 25.65 5 9 230 26.2 4.78 HVO_2338 homoserine kinase 25.60 1 3 3 11 2.140E8 10.06 25.60 3 6 301.95 19.80 2 5 293 29.8 4.88 HVO_2313 siroheme decarboxylase AhbB 25.50 1 6 6 22 7.067E8 17.12 25.50 6 11 1195.13 25.50 6 11 353 39.6 4.64 HVO_B0052 PQQ repeat protein 25.49 1 7 7 27 3.346E8 11.24 17.23 6 13 1309.07 25.49 7 14 412 44.1 5.48 HVO_1356 sensor box histidine kinase 25.45 1 9 10 29 3.225E8 14.60 25.45 10 15 1120.72 19.27 8 14 550 61.1 4.60 HVO_0049 argininosuccinate synthase 25.43 1 9 9 37 3.010E9 32.37 25.43 9 18 2165.21 25.43 9 19 405 44.5 4.34 HVO_2068 "FtsZ family protein, type III" 25.41 1 5 5 20 5.491E8 20.91 25.41 5 9 1756.77 25.41 5 11 370 38.7 4.49 HVO_1727 TATA-binding transcription initiation factor 25.27 1 5 5 33 1.885E9 32.51 25.27 5 16 2182.52 25.27 5 17 186 19.9 4.36 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 25.26 1 7 7 28 3.137E8 20.43 21.05 6 12 1843.86 25.26 7 16 475 49.3 4.49 HVO_0120 signal recognition particle receptor FtsY 25.22 1 6 6 24 2.948E8 10.51 25.22 6 12 1129.31 25.22 6 12 456 48.2 4.17 HVO_1048 phosphoribosylformylglycinamidine synthase 2 25.21 1 12 12 58 1.657E9 64.30 22.65 10 27 4569.05 25.21 12 31 702 72.9 4.18 HVO_1148 30S ribosomal protein S15 25.16 1 2 2 7 1.173E8 6.22 25.16 2 4 381.78 25.16 2 3 155 17.5 4.91 >sp|TRYP_PIG| 25.11 1 5 5 148 4.566E10 122.12 25.11 4 73 9696.51 25.11 5 75 231 24.4 7.18 HVO_2908 dihydropteroate synthase 25.07 1 7 7 21 3.890E8 10.35 25.07 7 11 762.43 22.16 6 10 379 40.8 4.53 HVO_C0077 sarcosine oxidase 25.06 1 5 5 16 2.902E8 15.90 25.06 5 8 1041.01 25.06 5 8 387 42.9 4.70 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 25.05 1 10 10 34 2.450E8 22.69 25.05 10 17 1735.31 25.05 10 17 459 50.5 4.63 HVO_2702 alpha/beta hydrolase fold protein 25.00 1 5 5 17 2.706E8 2.57 25.00 5 9 651.69 20.00 4 8 260 28.0 4.53 HVO_A0133 conserved hypothetical protein 25.00 1 5 5 21 3.750E8 18.85 25.00 5 11 1197.78 25.00 5 10 292 30.8 5.17 HVO_0916 diphthine synthase 24.91 1 5 5 12 3.233E8 12.57 24.91 5 6 718.82 24.91 5 6 269 29.1 4.54 HVO_A0273 ThuA family protein 24.89 1 3 3 12 1.307E8 8.84 24.89 3 6 475.20 24.89 3 6 237 26.5 4.77 HVO_0209 acyl-CoA dehydrogenase 24.81 1 7 7 29 1.763E8 31.05 24.81 7 14 2027.33 24.81 7 15 387 42.4 4.93 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 24.80 1 5 6 17 3.195E8 9.83 16.45 4 7 758.62 24.80 6 10 383 41.9 4.21 HVO_A0476 conserved hypothetical protein 24.77 1 5 5 14 2.794E8 4.63 24.77 5 7 486.54 24.77 5 7 331 35.4 4.26 HVO_0853 DNA double-strand break repair protein Mre11 24.72 1 8 8 24 2.682E8 18.47 24.72 8 13 1258.23 20.41 7 11 441 48.1 4.39 HVO_1725 Orc1-type DNA replication protein 24.69 1 7 8 25 1.078E8 15.41 22.19 7 11 1287.28 24.69 8 14 401 44.5 5.19 HVO_0937 FMN-binding domain protein 24.66 1 2 2 3 1.788E8 345.35 24.66 2 3 146 16.2 4.36 HVO_0854 DNA double-strand break repair ATPase Rad50 24.64 1 18 18 49 1.804E8 40.17 23.63 17 24 2758.64 24.64 18 25 893 100.0 4.58 HVO_0156 "tRNA (guanine(10),N(2))-dimethyltransferase" 24.61 1 7 7 17 7.380E7 16.02 20.25 6 8 840.21 24.61 7 9 321 34.2 5.25 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 24.59 1 5 5 19 1.570E8 13.26 24.59 5 10 895.52 24.59 5 9 305 32.7 4.56 HVO_1979 tRNA pseudouridine synthase Pus10 24.59 1 7 7 24 1.120E9 17.87 24.59 7 12 1433.90 18.74 6 12 427 46.9 4.39 HVO_2690 GFO family oxidoreductase 24.59 1 8 8 42 1.438E9 34.91 24.59 8 21 2954.57 24.59 8 21 366 40.0 4.60 HVO_C0043 conserved hypothetical protein 24.51 1 13 13 46 3.426E8 31.26 23.15 12 22 2624.78 24.51 12 24 661 73.8 4.75 HVO_2494 cytidylate kinase 24.48 1 2 2 2 8.908E7 2.11 24.48 2 2 192 21.6 4.44 HVO_1866 uridylate kinase 24.47 1 4 4 16 9.094E8 19.73 24.47 4 8 1164.99 24.47 4 8 237 24.6 4.42 HVO_2707 GFO family oxidoreductase 24.46 1 8 8 40 1.455E9 49.45 24.46 8 20 2984.22 24.46 8 20 372 41.0 4.55 HVO_B0057 precorrin-3B C17-methyltransferase 24.42 1 4 4 28 9.492E8 18.74 13.66 3 14 1925.62 24.42 4 14 344 36.3 4.31 HVO_2879 ornithine cyclodeaminase 24.40 1 5 5 25 8.987E8 14.91 16.87 4 10 1600.40 24.40 5 15 332 34.6 4.45 7428712 "keratin 1, type II, cytoskeletal - human" 24.26 1 0 15 98 1.638E9 92.14 24.26 15 49 6602.79 24.26 15 49 643 65.5 6.35 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 24.23 1 10 10 61 8.126E8 72.09 24.23 10 31 3812.34 24.23 10 30 615 67.6 4.88 HVO_1623 conserved hypothetical protein 24.16 1 5 5 22 3.738E8 24.13 24.16 5 11 1446.78 24.16 5 11 298 32.8 4.56 HVO_A0524 3-hydroxyacyl-CoA dehydrogenase 24.15 1 5 5 15 1.303E8 8.16 14.63 4 7 717.97 24.15 5 8 294 31.3 4.45 HVO_2481 HD family hydrolase 24.10 1 6 6 19 1.634E8 3.78 20.77 5 9 570.28 24.10 6 10 390 42.7 6.14 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 24.07 1 7 7 32 3.000E8 33.43 17.99 6 15 2026.60 24.07 7 17 378 39.8 4.45 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 24.05 1 14 14 41 1.557E8 18.18 20.41 13 20 1875.05 24.05 14 21 740 85.6 4.70 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 24.02 1 8 8 28 1.128E9 16.17 17.32 7 13 1371.29 24.02 8 15 612 67.3 4.16 HVO_0670 glutathione S-transferase 23.93 1 6 6 17 1.244E8 13.23 15.64 4 7 1014.76 23.93 6 10 326 38.1 4.56 HVO_B0084 conserved hypothetical protein 23.91 1 2 2 3 5.096E7 290.14 23.91 2 3 138 14.3 4.70 HVO_1510 2-isopropylmalate synthase 23.86 1 7 7 29 1.884E9 32.44 23.86 7 15 1762.64 23.86 7 14 440 47.7 4.82 HVO_1567 conserved hypothetical protein 23.83 1 4 4 8 2.984E8 6.34 23.83 4 5 389.18 12.77 2 3 235 25.7 4.36 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 23.79 1 4 4 12 3.812E8 12.31 23.79 4 6 749.19 23.79 4 6 269 28.3 4.49 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 23.77 1 6 6 22 2.410E8 24.09 23.77 6 11 1516.77 23.77 6 11 324 36.6 4.68 HVO_1412 diphosphomevalonate decarboxylase 23.77 1 8 8 27 1.839E9 17.58 23.77 8 14 1493.52 21.30 7 13 324 35.4 4.78 HVO_1550 acyl-CoA thioester hydrolase 23.75 1 3 3 11 3.675E8 12.29 16.88 2 5 664.02 23.75 3 6 160 17.6 4.55 HVO_A0547 DUF1028 family protein 23.72 1 5 5 11 4.360E8 5.88 23.72 5 6 456.26 21.02 4 5 333 35.2 4.16 HVO_0304 electron transfer flavoprotein alpha subunit 23.66 1 4 4 33 1.018E9 19.68 20.50 3 14 1565.07 23.66 4 19 317 33.5 4.18 HVO_1918 probable metallo-beta-lactamase family hydrolase 23.51 1 3 3 21 1.568E8 10.41 23.51 3 10 755.48 23.51 3 11 302 34.0 4.55 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 23.46 1 6 6 19 3.288E8 12.97 23.46 6 9 1110.57 23.46 6 10 422 43.6 4.72 HVO_A0636 YbaK domain protein 23.42 1 2 2 8 1.265E8 11.75 23.42 2 4 561.02 23.42 2 4 158 16.7 4.54 HVO_2912 ThiJ/PfpI domain protein 23.38 1 2 2 8 1.782E8 7.93 23.38 2 4 454.44 23.38 2 4 201 20.9 4.36 HVO_0699 translation initiation factor aIF-2 alpha subunit 23.31 1 6 6 27 7.909E8 24.33 23.31 6 14 1768.45 23.31 6 13 266 29.5 4.46 HVO_B0143 receiver/sensor box histidine kinase 23.28 1 11 11 40 5.139E8 36.02 23.28 11 20 2467.70 23.28 11 20 597 66.0 4.41 HVO_1453 glutamate dehydrogenase (NADP) 23.26 1 8 8 33 6.945E8 20.43 20.38 7 16 1781.42 23.26 8 17 417 45.7 4.49 HVO_1287 PfpI family protease 23.23 1 3 3 10 3.056E8 2.34 23.23 3 5 369.75 23.23 3 5 198 21.5 4.53 HVO_0694 probable phosphoribosyltransferase 23.21 1 5 5 19 3.044E8 14.01 23.21 5 10 1033.67 23.21 5 9 237 27.0 4.32 HVO_2266 hypothetical protein 23.12 1 8 8 39 4.178E8 17.92 23.12 8 20 1849.18 23.12 8 19 493 56.7 4.54 HVO_0220 ATP-dependent DNA helicase MCM 23.08 1 14 14 44 2.208E8 33.06 21.51 13 22 2162.55 22.08 13 22 702 78.8 4.73 HVO_0689 chromosome segregation protein Smc 23.06 1 23 23 63 4.677E8 42.28 23.06 23 32 3373.24 21.45 22 31 1240 138.1 4.39 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 23.01 1 6 6 25 4.331E8 18.80 23.01 6 13 1267.43 23.01 6 12 365 39.0 4.61 HVO_1375 O-succinylbenzoic acid--CoA ligase 22.96 1 10 10 32 3.275E8 26.64 22.96 10 16 1605.11 22.96 10 16 614 64.7 4.28 HVO_0970 ribulose-bisphosphate carboxylase large subunit 22.95 1 8 8 46 9.318E8 33.90 22.95 8 23 2687.70 22.95 8 23 414 43.9 4.59 HVO_2784 30S ribosomal protein S13 22.75 1 3 3 9 2.188E8 9.63 11.98 2 4 686.44 22.75 3 5 167 18.9 5.17 HVO_0150 urease accessory protein UreG 22.71 1 2 2 2 3.889E7 0.00 22.71 2 2 207 22.2 4.55 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 22.69 1 8 8 69 4.369E9 59.01 22.69 8 35 3994.93 22.69 7 34 357 40.3 4.40 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 22.62 1 7 7 22 1.570E8 22.49 22.62 7 11 1181.49 22.62 7 11 420 45.0 4.86 HVO_0551 DNA mismatch repair protein MutL 22.59 1 10 10 43 4.240E8 47.85 22.59 10 21 2512.91 22.59 10 22 735 78.7 4.50 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 22.41 1 6 6 21 2.655E8 13.41 22.41 6 11 1054.79 20.20 5 10 406 43.1 4.60 HVO_1570 DNA topoisomerase VI subunit A 22.40 1 5 5 15 6.060E8 6.92 22.40 5 7 753.24 22.40 5 8 366 41.8 4.63 HVO_1932 2-D-hydroxyacid dehydrogenase 22.40 1 6 6 24 4.190E8 25.69 22.40 6 12 1592.08 22.40 6 12 308 33.0 4.60 HVO_1711 glucoamylase 22.37 1 24 24 77 5.522E8 72.27 22.37 24 39 4653.05 20.52 22 38 1511 166.1 4.64 HVO_1503 3-isopropylmalate dehydratase small subunit 22.28 1 3 3 10 5.680E8 6.71 13.37 2 4 732.62 22.28 3 6 202 22.0 4.15 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 22.26 1 4 4 16 1.844E8 12.35 22.26 4 8 853.28 22.26 4 8 265 28.7 4.87 HVO_0558 SAMP-activating enzyme E1 22.22 1 4 4 10 2.187E8 0.00 18.15 3 4 407.15 22.22 4 6 270 28.7 4.35 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 22.22 1 4 4 16 3.884E8 15.06 22.22 4 8 1214.55 22.22 4 8 324 33.6 3.99 HVO_1629 conserved hypothetical protein 22.22 1 9 9 28 2.325E8 19.21 22.22 9 14 1485.54 22.22 9 14 531 56.3 4.69 HVO_1989 tRNA (pseudouridine(54)-N(1))-methyltransferase 22.22 1 2 2 4 8.282E7 0.00 22.22 2 2 106.54 22.22 2 2 198 21.9 4.79 HVO_1804 nicotinate phosphoribosyltransferase 22.16 1 7 7 26 5.196E8 23.30 19.07 6 12 1660.35 22.16 7 14 388 41.1 4.60 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 22.15 1 5 5 13 2.136E8 9.92 22.15 5 7 742.68 13.47 4 6 438 46.4 4.58 HVO_1340 "probable glycosyltransferase, type 1" 22.13 1 7 7 30 6.535E8 24.90 22.13 7 15 1921.77 22.13 7 15 375 41.0 4.42 HVO_2952 tRNA-splicing endonuclease 22.12 1 5 5 18 2.608E8 14.76 22.12 5 9 909.29 22.12 5 9 339 37.4 4.74 HVO_0814 DnaJ N-terminal domain protein 22.11 1 2 2 2 1.847E8 0.00 22.11 2 2 199 22.2 5.68 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 22.06 1 6 6 30 4.958E8 38.55 22.06 6 15 2043.31 22.06 6 15 349 37.0 4.70 HVO_0876 methylglyoxal synthase 22.05 1 2 2 6 2.008E8 4.93 22.05 2 3 458.30 22.05 2 3 127 13.9 4.48 HVO_A0505 enoyl-CoA hydratase 22.05 1 3 3 5 4.545E7 0.00 22.05 3 3 28.72 18.50 2 2 254 26.6 4.55 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 22.01 1 8 8 24 3.456E8 19.15 22.01 8 12 1193.11 22.01 8 12 586 63.4 4.70 HVO_2871 pyridoxal phosphate-dependent aminotransferase 22.00 1 7 7 24 1.946E8 25.67 22.00 7 12 1543.22 22.00 7 12 450 49.1 4.70 HVO_A0571 isochorismatase family protein 21.92 1 2 2 4 6.636E7 4.19 21.92 2 2 255.48 21.92 2 2 219 24.3 4.39 HVO_1578 probable NADH dehydrogenase 21.91 1 4 4 11 4.071E8 7.76 12.34 3 5 523.17 21.91 4 6 397 42.8 4.40 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 21.88 1 11 11 33 3.784E8 28.79 20.52 10 16 2028.15 21.88 11 17 658 72.1 4.70 HVO_2662 homolog to lactoylglutathione lyase 21.88 1 5 5 19 1.274E9 15.33 18.84 4 9 1148.98 21.88 5 10 329 36.5 4.48 HVO_A0257 Orc1-type DNA replication protein 21.88 1 7 7 19 1.348E8 9.49 21.88 7 9 884.06 21.88 7 10 425 48.0 4.94 HVO_1585 acyl-CoA synthetase 21.71 1 10 10 40 1.072E9 37.32 21.71 10 19 2434.81 21.71 10 21 668 74.1 4.48 HVO_0001 Orc1-type DNA replication protein 21.63 1 10 10 32 1.768E8 27.96 21.63 10 16 2185.42 21.63 10 16 564 62.1 4.39 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 21.58 1 4 4 10 7.296E7 4.34 21.58 4 5 440.56 21.58 4 5 241 26.1 4.58 HVO_2581 quinolinate synthase A 21.56 1 7 7 32 5.918E8 21.07 18.96 6 15 1687.65 21.56 7 17 385 42.0 4.41 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 21.50 1 5 5 15 1.315E8 14.27 21.50 5 8 771.08 13.99 4 7 386 41.3 4.46 HVO_1413 probable NADH dehydrogenase 21.49 1 6 6 24 2.890E8 18.39 21.49 6 12 1357.34 21.49 6 12 377 39.7 4.67 HVO_B0054 sirohydrochlorin cobaltochelatase 21.43 1 5 5 7 1.514E8 0.00 6.65 2 2 304.74 21.43 5 5 406 44.1 4.72 HVO_2945 valine--tRNA ligase 21.26 1 15 15 88 1.896E9 61.56 19.77 14 45 5507.02 17.24 14 43 870 98.9 4.36 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 21.24 1 5 5 25 5.195E8 24.94 21.24 5 12 1737.04 21.24 5 13 386 42.1 4.49 HVO_1446 "fructose-1,6-bisphosphatase" 21.21 1 4 4 13 1.362E8 11.62 17.17 3 6 925.47 21.21 4 7 297 31.6 4.45 HVO_1723 DNA repair helicase Rad25 21.15 1 11 11 35 1.413E8 18.08 20.29 10 17 1838.24 21.15 11 18 695 76.8 4.69 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 21.13 1 4 4 9 1.275E8 1.95 21.13 4 5 228.95 9.54 3 4 388 41.9 4.35 HVO_2427 replication factor C large subunit 21.11 1 9 9 28 3.254E8 33.00 19.67 8 14 1763.02 21.11 9 14 488 53.4 4.67 HVO_1268 conserved hypothetical protein 21.10 1 4 4 10 1.186E8 9.83 21.10 4 5 657.86 21.10 4 5 237 26.4 5.21 HVO_A0583 IclR family transcription regulator 21.09 1 5 5 12 1.425E8 5.07 21.09 5 6 586.04 21.09 5 6 256 27.9 5.07 HVO_0043 acetylornithine aminotransferase 20.90 1 6 6 31 2.920E9 25.64 20.90 6 15 2355.57 20.90 6 16 378 39.7 4.67 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 20.89 1 6 6 23 2.858E8 15.03 12.79 4 10 1431.67 20.89 6 13 383 42.0 4.49 HVO_B0055 conserved hypothetical protein 20.89 1 5 5 18 7.732E8 7.04 20.89 5 9 773.75 20.89 5 9 225 23.9 4.69 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 20.88 1 2 2 10 1.512E8 5.35 20.88 2 5 434.86 20.88 2 5 91 10.4 4.07 HVO_0233 ribose-phosphate pyrophosphokinase 20.85 1 4 4 20 3.102E8 14.84 20.85 4 10 1118.36 20.85 4 10 283 29.6 4.40 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 20.75 1 4 4 16 2.474E8 12.43 20.75 4 8 864.79 20.75 4 8 294 32.5 4.75 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 20.73 1 5 5 31 1.089E9 19.73 20.73 5 16 1587.89 20.73 5 15 357 39.8 4.41 HVO_B0324 conserved hypothetical protein 20.71 1 7 7 21 2.649E8 20.44 20.71 7 11 1417.15 18.04 6 10 449 48.0 4.58 HVO_0760 "probable glycosyltransferase, type 2" 20.65 1 6 6 23 3.720E8 12.51 20.65 6 12 1057.66 20.65 6 11 368 40.7 4.82 HVO_1657 phosphoribosylamine--glycine ligase 20.56 1 8 8 39 2.520E9 32.20 17.76 7 19 2337.70 20.56 8 20 428 45.5 4.20 HVO_0733 transcription initiation factor TFB 20.55 1 3 7 23 8.227E8 11.30 17.48 6 11 1235.52 20.55 7 12 326 37.2 6.00 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 20.49 1 6 6 19 3.214E8 18.50 17.13 5 9 1124.46 20.49 6 10 327 36.0 4.73 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 20.47 1 5 5 23 4.957E8 17.16 20.47 5 10 1092.07 20.47 5 13 430 45.1 4.50 HVO_A0328 2-keto-3-deoxygluconate kinase 20.44 1 4 5 18 2.500E8 11.33 20.44 5 9 766.82 20.44 5 9 318 34.0 4.60 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 20.40 1 3 3 10 5.499E8 6.63 6.69 2 5 494.26 20.40 3 5 299 32.0 4.53 HVO_A0307 Lrp/AsnC family transcription regulator 20.34 1 3 3 10 1.260E8 8.04 20.34 3 5 555.42 20.34 3 5 177 19.4 4.39 HVO_0328 NAD-dependent epimerase/dehydratase 20.27 1 3 3 7 6.133E7 0.00 20.27 3 4 266.42 7.77 2 3 296 31.7 5.07 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 20.21 1 8 8 21 1.770E8 6.73 19.18 7 10 699.27 20.21 8 11 584 63.3 4.79 HVO_B0382 TATA-binding transcription initiation factor 20.21 1 3 3 14 3.091E8 12.46 20.21 3 7 812.57 20.21 3 7 188 20.1 4.12 HVO_0402 DUF124 family protein 20.00 1 3 3 10 1.418E8 3.85 20.00 3 5 396.32 20.00 3 5 225 24.0 4.58 HVO_A0586 sugar nucleotidyltransferase 19.95 1 7 7 23 4.000E8 14.66 19.95 7 12 1331.43 17.52 6 11 411 43.7 4.69 HVO_1485 conserved hypothetical protein 19.91 1 3 3 6 2.016E9 0.00 18.96 2 2 152.73 19.91 3 4 211 23.0 4.42 47132620 keratin 2a [Homo sapiens] 19.87 1 8 11 43 1.249E9 35.16 19.87 11 22 2786.38 19.87 11 21 639 65.4 8.00 HVO_1568 alpha/beta hydrolase fold protein 19.86 1 5 5 16 9.348E7 14.40 19.86 5 8 804.47 19.86 5 8 277 29.4 4.94 HVO_2951 tryptophan--tRNA ligase 19.85 1 9 9 38 4.487E8 24.48 19.85 9 20 1722.52 15.12 8 18 529 59.1 4.53 HVO_2211 TrkA domain protein 19.82 1 4 4 9 2.207E8 3.67 19.82 4 5 328.02 16.30 3 4 227 24.5 4.72 HVO_0896 acyl-CoA synthetase 19.81 1 9 9 30 2.909E8 21.39 19.81 9 16 1405.96 19.81 9 14 540 59.8 4.56 HVO_1179 homolog to NAD kinase 19.77 1 5 5 11 1.126E8 3.85 16.95 4 5 390.36 19.77 5 6 354 36.7 4.60 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 19.75 1 5 5 11 1.567E8 8.01 9.62 3 4 792.04 19.75 5 7 395 42.4 4.54 HVO_1685 conserved hypothetical protein 19.72 1 9 9 25 3.374E8 10.38 16.06 7 12 1034.48 17.89 8 13 492 54.5 5.74 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 19.71 1 3 3 7 1.632E8 5.10 19.71 3 4 303.00 19.71 3 3 208 22.6 4.36 HVO_0214 L-lactate dehydrogenase 19.69 1 6 6 38 2.946E9 34.78 19.69 6 19 2691.27 19.69 6 19 320 34.5 4.49 HVO_A0485 aminotransferase class V 19.66 1 5 5 16 2.767E8 15.87 19.66 5 8 1113.37 19.66 5 8 351 37.3 4.26 HVO_2453 anthranilate synthase component II 19.61 1 2 2 5 1.535E8 2.43 19.61 2 2 213.03 19.61 2 3 204 21.8 4.55 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 19.57 1 2 2 9 2.370E8 4.99 19.57 2 5 276.35 19.57 2 4 184 20.0 4.75 HVO_1878 NAD synthase 19.57 1 5 5 25 2.854E8 12.97 19.57 5 13 1056.29 19.57 5 12 276 29.6 4.37 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 19.56 1 7 7 25 4.657E8 24.52 19.56 7 12 1205.13 19.56 7 13 634 66.1 4.54 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 19.54 1 4 4 13 2.256E8 2.52 19.54 4 6 379.28 19.54 4 7 348 36.7 4.69 HVO_A0498 conserved hypothetical protein 19.53 1 6 6 15 1.474E8 6.27 19.53 6 7 629.42 19.53 6 8 379 42.7 4.55 HVO_1740 conserved hypothetical protein 19.52 1 2 2 3 7.479E7 0.00 19.52 2 3 210 24.4 4.49 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 19.41 1 4 4 10 1.554E8 3.82 19.41 4 5 400.27 19.41 4 5 237 25.4 4.46 HVO_0769 TRAM domain protein 19.40 1 2 2 6 7.169E7 4.53 19.40 2 3 308.15 19.40 2 3 134 14.8 4.32 HVO_0454 ornithine cyclodeaminase 19.34 1 3 3 8 1.579E8 5.22 19.34 3 4 363.77 19.34 3 4 331 35.6 4.23 HVO_0712 shikimate dehydrogenase (nonfunctional) 19.33 1 3 3 7 1.083E8 5.60 19.33 3 4 254.84 14.87 2 3 269 27.7 4.65 HVO_0180 23S rRNA (uridine-2'-O-) methyltransferase 19.31 1 4 4 10 1.116E8 1.94 19.31 4 5 322.60 19.31 4 5 259 28.3 4.70 HVO_0234 conserved hypothetical protein 19.27 1 3 3 7 9.971E7 5.25 13.82 2 3 361.13 19.27 3 4 275 28.1 4.48 HVO_3000 DNA ligase (NAD) 19.17 1 8 8 27 8.449E8 26.23 18.31 7 14 1577.47 17.74 7 13 699 75.8 4.50 HVO_1579 uridine phosphorylase 19.12 1 3 3 11 1.569E8 5.96 19.12 3 5 565.08 19.12 3 6 272 29.0 4.64 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 19.03 1 4 4 14 6.957E7 11.44 19.03 4 7 575.61 19.03 4 7 268 27.9 4.87 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 18.97 1 6 6 23 4.442E8 18.19 18.97 6 11 1195.83 18.97 6 12 464 53.1 4.54 HVO_1289 OsmC domain protein 18.94 1 2 2 3 2.532E9 4.97 18.94 2 3 132 14.2 3.85 HVO_0741 DNA-directed DNA polymerase X 18.90 1 6 6 17 2.416E8 8.96 15.46 5 8 845.64 18.90 6 9 582 62.6 4.44 HVO_1941 AAA-type ATPase (MoxR subfamily) 18.87 1 4 4 11 6.595E7 1.73 14.78 3 5 286.91 18.87 4 6 318 34.8 4.83 HVO_0054 glycine--tRNA ligase 18.86 1 7 7 33 3.165E9 39.44 16.50 6 15 3224.40 18.86 7 18 594 64.9 4.21 HVO_0697 PAC2 family protein 18.82 1 2 2 12 5.160E8 18.38 18.82 2 6 901.42 18.82 2 6 255 27.4 4.08 HVO_2001 tRNA-guanine(15) transglycosylase 18.80 1 5 5 20 2.783E8 16.74 18.80 5 11 1150.44 15.31 4 9 516 56.3 4.59 HVO_A0002 conserved hypothetical protein 18.75 1 2 2 7 1.311E8 8.85 18.75 2 3 704.02 18.75 2 4 192 20.7 4.02 HVO_1407 HTH domain protein 18.67 1 3 3 8 6.481E7 4.85 18.67 3 4 491.14 18.67 3 4 225 24.9 4.45 HVO_0768 radical SAM domain protein 18.58 1 6 6 12 1.466E8 2.71 10.27 4 5 378.71 18.58 6 7 565 62.0 4.84 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 18.58 1 4 4 10 1.959E8 0.00 13.31 3 4 290.49 18.58 4 6 323 34.9 5.24 HVO_B0049 precorrin-8 methylmutase 18.58 1 3 3 5 8.055E7 2.64 11.50 2 2 214.54 18.58 3 3 226 23.8 5.00 HVO_2763 homolog to ribonuclease Z 18.55 1 4 4 20 2.835E8 4.54 18.55 4 11 700.41 18.55 4 9 248 26.6 4.53 HVO_B0130 DUF296 family protein 18.52 1 2 2 11 2.238E8 4.82 18.52 2 6 443.11 18.52 2 5 135 14.8 4.41 HVO_1895 KEOPS complex subunit Kae1/Bud32 18.48 1 7 7 16 1.995E8 21.01 18.48 7 8 1217.88 18.48 7 8 552 59.0 5.07 HVO_0014 ATP-dependent DNA helicase Hel308a 18.38 1 13 13 42 2.780E8 25.00 18.38 13 21 1930.23 18.38 13 21 827 90.3 4.67 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 10 3.335E8 13.13 18.29 4 5 842.25 18.29 4 5 257 26.8 4.01 HVO_2923 proteasome alpha subunit 18.07 1 3 4 12 4.617E8 4.35 18.07 4 6 576.41 18.07 4 6 249 26.7 4.39 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 18.06 1 5 5 23 5.809E8 22.26 13.06 3 9 1907.49 18.06 5 14 360 38.5 4.45 HVO_A0550 receiver/sensor box histidine kinase 17.97 1 14 15 38 1.803E8 26.96 16.50 14 19 1905.83 17.74 14 19 885 95.9 4.46 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 17.90 1 19 19 59 3.538E8 28.17 17.90 19 29 2474.54 17.38 18 30 1335 150.5 4.60 HVO_1861 thiamine-monophosphate kinase 17.85 1 5 5 14 1.364E8 12.36 17.85 5 7 758.68 17.85 5 7 297 30.8 4.32 HVO_2263 conserved hypothetical protein 17.85 1 10 10 22 1.540E8 14.86 14.73 9 10 933.77 17.85 10 12 801 89.5 5.54 HVO_3014 origin-associated GTP-binding protein OapA 17.84 1 4 4 7 1.756E8 2.58 14.55 3 3 343.55 17.84 4 4 213 24.0 5.01 HVO_1098 diaminopimelate decarboxylase 17.83 1 6 6 24 5.022E8 13.73 17.83 6 11 1058.87 17.83 6 13 415 44.4 5.02 HVO_0414 peptidase M24 family protein 17.80 1 3 3 10 1.230E8 0.00 17.80 3 5 213.97 17.80 3 5 382 39.4 4.82 HVO_2614 uridine phosphorylase 17.77 1 3 3 13 1.203E9 9.84 7.85 2 6 837.41 17.77 3 7 242 25.8 4.30 HVO_C0044 PLD domain protein 17.72 1 4 4 10 1.224E8 3.92 17.72 4 5 397.28 17.72 4 5 333 36.4 4.94 HVO_1129 conserved hypothetical protein 17.69 1 4 5 23 3.431E8 20.36 17.69 5 12 1086.20 16.41 4 11 390 43.0 4.44 HVO_B0154 receiver/sensor box histidine kinase 17.68 1 17 17 56 3.522E8 38.88 17.68 17 27 2984.59 17.68 17 29 1301 144.1 4.39 HVO_0354 30S ribosomal protein S7 17.65 1 3 3 12 5.408E8 9.09 17.65 3 6 629.67 17.65 3 6 204 22.6 5.14 HVO_1139 squalene synthase 17.60 1 4 4 20 3.435E8 19.32 17.60 4 10 1320.84 17.60 4 10 358 39.7 4.54 HVO_2600 methionyl aminopeptidase 17.57 1 6 6 16 4.451E8 6.91 11.82 4 6 821.26 17.57 6 10 296 32.3 4.41 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 17.49 1 4 4 14 5.233E8 22.11 17.49 4 7 1455.17 17.49 4 7 446 47.9 4.39 HVO_2906 tRNA (cytidine/uridine-2'-O-)-methyltransferase 17.45 1 3 3 8 8.238E7 2.28 17.45 3 4 209.88 17.45 3 4 275 30.6 4.58 HVO_2108 IclR family transcription regulator 17.39 1 3 3 5 9.447E7 0.00 13.04 2 2 166.12 17.39 3 3 253 28.0 5.74 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 17.30 1 10 10 35 2.756E8 22.91 17.30 10 18 1615.46 17.30 10 17 838 89.1 4.65 HVO_A0003 ParA domain protein 17.15 1 4 4 17 1.525E8 4.10 17.15 4 8 599.29 17.15 4 9 274 30.3 4.53 HVO_2347 conserved hypothetical protein 17.14 1 2 2 4 5.116E7 0.00 17.14 2 2 134.02 17.14 2 2 140 15.5 4.37 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 17.13 1 4 4 15 2.529E8 6.76 17.13 4 8 535.18 17.13 4 7 286 30.8 4.46 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 17.12 1 6 6 39 1.184E8 22.19 14.89 5 18 1960.94 17.12 6 21 403 41.1 4.73 HVO_2852 succinylglutamate desuccinylase/aspartoacylase family protein 17.01 1 3 3 6 6.069E7 0.00 17.01 3 3 176.19 17.01 3 3 288 31.3 4.58 HVO_1073 ThiJ/PfpI family protein 16.96 1 3 3 12 2.668E8 15.24 16.96 3 6 850.22 16.96 3 6 224 23.9 4.12 HVO_A0486 hydrogenase expression/formation protein 16.96 1 3 3 15 1.390E8 10.56 16.96 3 8 627.29 16.96 3 7 336 33.8 4.06 HVO_2564 50S ribosomal protein L3 16.86 1 4 4 16 1.466E8 6.37 16.86 4 8 696.30 16.86 4 8 338 37.2 6.68 HVO_1272 TrmB family transcription regulator 16.85 1 3 3 9 1.222E8 10.01 6.91 2 4 693.53 16.85 3 5 362 40.5 4.48 HVO_2350 YyaL family protein 16.85 1 7 7 20 2.429E8 2.25 16.85 7 10 623.85 15.58 6 10 552 58.8 4.59 HVO_0848 endonuclease III 16.74 1 2 2 4 5.806E7 0.00 16.74 2 2 51.12 16.74 2 2 227 25.5 4.55 HVO_B0375 Spo0M family protein 16.73 1 2 2 7 1.218E8 4.78 16.73 2 3 426.50 16.73 2 4 245 27.2 4.35 HVO_2998 homoserine O-acetyltransferase 16.63 1 4 4 16 1.873E8 10.73 16.63 4 8 859.14 16.63 4 8 415 44.8 4.69 HVO_2761 mevalonate kinase 16.62 1 4 4 12 1.613E8 0.00 16.62 4 6 249.17 16.62 4 6 367 38.2 4.31 HVO_B0266 glutamate dehydrogenase (NAD) 16.55 1 8 8 22 3.550E8 17.13 16.55 8 12 1196.01 14.02 7 10 435 47.3 4.63 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 16.49 1 3 3 12 2.166E8 4.64 16.49 3 6 498.58 16.49 3 6 97 10.8 4.53 HVO_1121 Fe-coproporphyrin synthase AhbC 16.42 1 5 5 16 1.112E8 5.87 16.42 5 8 719.32 16.42 5 8 402 44.4 4.67 HVO_2639 DUF1611 family protein 16.42 1 3 3 11 3.040E8 14.14 16.42 3 6 761.95 6.74 2 5 341 36.3 4.44 HVO_A0305 methylmalonate-semialdehyde dehydrogenase 16.36 1 5 5 18 2.265E8 19.05 16.36 5 9 1030.95 16.36 5 9 489 52.1 4.59 HVO_2072 S-layer glycoprotein 16.32 1 6 6 95 4.832E9 49.26 16.32 6 51 2394.10 16.32 6 44 827 85.1 3.65 HVO_1821 GNAT family acetyltransferase Pat2 16.30 1 2 2 6 7.678E7 6.05 16.30 2 3 397.32 16.30 2 3 184 20.4 4.30 HVO_0319 A-type ATP synthase subunit D 16.17 1 3 3 8 2.881E7 9.10 16.17 3 4 422.07 16.17 3 4 235 26.7 4.72 HVO_2255 conserved hypothetical protein 16.10 1 4 4 10 6.600E7 5.28 16.10 4 5 420.23 16.10 4 5 236 27.7 5.60 HVO_1562 proteasome beta subunit 16.05 1 2 2 6 1.018E8 5.41 16.05 2 3 422.34 16.05 2 3 243 26.0 4.63 HVO_2060 NUDIX family hydrolase 16.03 1 2 2 6 2.181E8 0.00 16.03 2 3 115.25 16.03 2 3 156 17.7 4.41 HVO_A0064 Orc1-type DNA replication protein 16.03 1 4 5 14 1.280E8 7.93 16.03 5 7 476.26 16.03 5 7 499 55.5 4.91 HVO_2554 50S ribosomal protein L14 15.91 1 2 2 4 8.519E7 3.44 15.91 2 2 101.91 15.91 2 2 132 14.2 9.76 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 15.85 1 3 3 11 2.793E8 2.77 15.85 3 6 586.90 13.66 2 5 183 20.0 4.21 HVO_0190 TIGR00268 family protein 15.77 1 4 4 7 9.275E7 2.56 15.77 4 4 236.09 13.09 3 3 298 32.5 4.60 HVO_1812 conserved hypothetical protein 15.73 1 4 4 10 1.252E8 9.13 15.73 4 5 470.45 12.80 3 5 375 40.5 4.50 HVO_A0553 adenosylcobyric acid synthase 15.63 1 4 4 15 8.309E7 11.13 15.63 4 7 639.27 15.63 4 8 512 52.6 4.50 HVO_1323 "shikimate kinase, archaeal-type" 15.57 1 3 3 11 3.429E8 10.82 15.57 3 5 770.71 15.57 3 6 289 29.5 4.30 HVO_0145 replication factor C small subunit 15.54 1 5 5 12 9.035E7 0.00 15.54 5 6 275.78 13.49 4 6 341 37.8 4.93 HVO_0755 NAD-dependent epimerase/dehydratase 15.44 1 3 3 9 1.044E8 3.78 15.44 3 5 300.60 15.44 3 4 298 32.3 4.91 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 15.37 1 6 6 24 5.098E8 25.55 15.37 6 13 1456.61 13.24 5 11 423 43.9 4.31 HVO_0069 sulfatase 15.34 1 6 6 15 7.508E7 9.40 12.04 5 6 906.92 15.34 6 9 515 57.4 4.35 HVO_B0058 precorrin-3B C17-methyltransferase 15.31 1 3 3 12 1.623E8 15.02 15.31 3 6 1018.40 15.31 3 6 294 31.8 4.40 HVO_A0306 4-aminobutyrate aminotransferase 15.28 1 5 5 13 1.052E8 10.69 12.36 4 6 757.45 15.28 5 7 445 47.6 4.68 HVO_0195 ribose-5-phosphate isomerase 15.22 1 3 3 13 3.111E8 13.20 11.74 2 6 847.13 15.22 3 7 230 23.2 4.54 HVO_1746 DUF2800 family protein 15.17 1 3 3 5 8.832E7 0.00 9.29 2 2 250.33 15.17 3 3 323 36.5 4.37 HVO_1879 enoyl-CoA hydratase 15.15 1 2 2 2 1.111E8 0.00 15.15 2 2 231 24.3 5.21 HVO_B0200 malate synthase 14.91 1 4 4 16 8.532E8 12.17 14.91 4 8 805.15 14.91 4 8 436 48.3 4.30 HVO_2503 kynureninase 14.82 1 5 5 10 1.449E8 1.91 12.00 4 4 491.66 14.82 5 6 425 46.0 4.54 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 14.80 1 3 3 9 2.843E8 11.19 10.83 2 4 787.98 14.80 3 5 277 30.6 4.30 HVO_1235 creatininase 14.77 1 2 2 10 1.448E8 10.11 14.77 2 5 694.08 14.77 2 5 264 29.2 4.84 HVO_2880 probable peptide chain release factor pelota 14.61 1 4 4 12 2.116E8 7.19 14.61 4 6 507.59 14.61 4 6 356 39.3 4.63 HVO_1309 peptidase M24 family protein 14.58 1 4 4 11 1.734E8 3.56 7.16 3 5 346.91 14.58 4 6 391 42.1 4.36 HVO_0056 conserved hypothetical protein 14.58 1 2 2 3 1.232E7 370.10 14.58 2 3 192 20.9 4.16 HVO_2479 2-phospho-L-lactate transferase 14.55 1 4 4 11 2.581E8 9.25 10.91 3 5 802.19 14.55 4 6 330 34.7 4.32 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 14.53 1 5 5 16 2.194E8 9.42 14.53 5 8 710.20 14.53 5 8 406 45.5 5.08 HVO_A0082 IclR family transcription regulator 14.51 1 3 3 7 3.767E7 0.00 7.84 2 3 284.64 14.51 3 4 255 28.3 4.92 HVO_0818 threonine synthase 14.14 1 5 5 22 5.335E8 26.48 14.14 5 11 1638.54 14.14 5 11 389 40.8 4.31 HVO_1354 DNA mismatch repair protein MutS 14.14 1 6 6 17 1.501E8 12.43 10.34 5 8 1041.50 11.38 5 9 580 62.1 4.56 HVO_B0295 ABC-type transport system ATP-binding protein (probable substrate glycerol-3-phosphate) 14.06 1 2 3 3 3.097E7 0.00 14.06 3 3 377 41.2 4.74 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 14.05 1 4 4 31 9.264E8 27.76 12.67 3 15 2192.01 14.05 4 16 363 39.7 4.25 HVO_0572 lipoate-protein ligase 13.82 1 4 4 11 1.931E8 13.83 12.73 3 5 861.23 13.82 4 6 275 30.5 4.84 HVO_0591 L-threonine-O-3-phosphate decarboxylase 13.82 1 3 3 6 7.231E7 1.64 13.82 3 3 154.19 13.82 3 3 340 36.0 4.54 HVO_1610 conserved hypothetical protein 13.78 1 2 2 10 1.062E8 8.40 13.78 2 5 550.95 13.78 2 5 283 30.5 4.55 HVO_1357 receiver/bat box HTH-10 family transcription regulator 13.75 1 5 5 15 2.000E8 12.70 13.75 5 7 735.99 13.75 5 8 582 62.7 4.40 HVO_A0021 conserved hypothetical protein 13.74 1 2 2 3 8.572E7 355.67 13.74 2 3 131 14.9 4.42 HVO_0835 acetyl-CoA C-acetyltransferase 13.66 1 3 3 10 2.185E8 8.02 8.76 2 5 471.13 13.66 3 5 388 40.1 4.78 HVO_1208 conserved hypothetical protein 13.64 1 2 2 2 4.409E7 0.00 13.64 2 2 220 23.5 4.48 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 13.61 1 4 4 22 2.155E8 21.49 13.61 4 11 1448.22 13.61 4 11 360 39.5 4.31 HVO_2160 conserved hypothetical protein 13.60 1 19 20 142 4.881E9 174.56 12.58 18 71 12886.79 13.20 19 71 2257 232.7 3.92 HVO_0469 AstE family protein 13.52 1 3 3 7 2.887E8 7.28 13.52 3 4 464.24 10.38 2 3 318 33.9 5.85 HVO_0326 CTP-dependent riboflavin kinase 13.50 1 3 3 12 2.430E8 10.04 13.50 3 6 752.73 13.50 3 6 237 25.9 4.55 HVO_2529 probable oxidoreductase (short-chain dehydrogenase family) 13.48 1 2 2 8 4.734E7 8.10 13.48 2 4 326.80 13.48 2 4 230 23.6 4.72 HVO_2158 malic enzyme (NADP) 13.45 1 2 5 43 5.742E8 28.45 13.45 5 21 1882.82 13.45 5 22 751 81.4 4.55 HVO_2888 homolog to elongator complex protein ELP3 13.45 1 5 5 14 9.822E7 11.24 13.45 5 7 570.34 13.45 5 7 550 62.6 5.01 HVO_0194 Orc1-type DNA replication protein 13.37 1 5 5 13 1.235E8 0.00 10.43 4 6 438.93 13.37 5 7 374 42.2 4.94 HVO_B0110 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 13.37 1 3 3 8 1.699E8 7.16 13.37 3 4 514.16 13.37 3 4 344 36.6 4.59 HVO_0675 pantoate kinase 13.36 1 3 3 11 1.146E8 9.55 13.36 3 5 561.05 13.36 3 6 277 27.8 4.54 HVO_2321 bacterial-type DNA primase DnaG 13.35 1 6 6 18 2.500E8 11.21 13.35 6 9 822.02 13.35 6 9 472 49.4 4.36 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 13.28 1 4 4 10 2.870E8 2.49 13.28 4 5 285.82 13.28 4 5 482 50.6 4.31 HVO_B0102 glycosidase family protein 13.24 1 4 4 9 2.432E7 3.97 10.42 3 4 331.02 13.24 4 5 355 38.7 4.75 HVO_1925 probable GTP-binding protein 13.23 1 4 4 12 1.015E8 1.71 13.23 4 6 440.65 13.23 4 6 325 36.5 4.72 HVO_A0158 acyl-CoA synthetase 13.23 1 2 5 30 3.764E9 18.49 13.23 5 13 1499.41 13.23 5 17 650 71.2 4.63 HVO_0044 acetylglutamate kinase 13.15 1 3 3 10 4.314E8 10.92 13.15 3 5 840.90 13.15 3 5 327 33.2 4.49 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 13.12 1 4 4 12 1.482E8 4.02 8.14 3 5 505.65 13.12 4 7 381 40.5 4.51 HVO_0600 ACT domain protein 12.99 1 2 2 8 1.274E8 4.07 12.99 2 4 445.12 12.99 2 4 177 19.2 4.44 HVO_0990 DHH family phosphoesterase 12.96 1 4 4 10 1.449E8 7.23 8.64 3 4 474.61 12.96 4 6 486 51.9 4.59 HVO_1698 CBS/parB domain protein 12.83 1 2 3 9 6.500E7 0.00 12.83 3 4 252.39 12.83 3 5 265 29.4 4.92 HVO_2229 flavin-containing amine-oxidoreductase 12.79 1 3 3 10 1.973E8 0.00 12.79 3 5 423.32 12.79 3 5 344 37.9 4.92 HVO_1564 conserved hypothetical protein 12.77 1 5 5 18 1.568E8 8.42 12.77 5 9 710.91 12.77 5 9 509 56.5 4.65 HVO_1199 acyl-CoA dehydrogenase 12.63 1 4 4 16 2.600E8 12.87 12.63 4 8 685.82 12.63 4 8 380 41.5 4.64 HVO_0889 FAD-dependent oxidoreductase 12.62 1 2 2 11 1.761E8 15.68 12.62 2 6 1288.40 12.62 2 5 214 21.8 3.89 HVO_2955 DEAD/DEAH box helicase 12.58 1 7 7 26 1.980E8 21.70 12.58 7 13 1370.95 12.58 7 13 779 85.8 4.94 HVO_A0286 DUF187 family protein 12.57 1 2 2 9 6.138E7 0.00 12.57 2 5 161.72 12.57 2 4 382 42.2 4.75 HVO_1710 alpha amylase 12.56 1 7 7 30 3.849E8 17.27 12.56 7 15 1594.75 12.56 7 15 677 75.0 4.45 HVO_2958 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit 12.50 1 2 2 2 3.193E7 1.71 12.50 2 2 368 40.9 4.68 HVO_B0101 IclR family transcription regulator 12.45 1 3 3 12 7.211E7 10.77 12.45 3 6 730.30 12.45 3 6 257 28.6 5.02 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 12.41 1 3 3 9 1.227E8 2.17 12.41 3 5 476.04 12.41 3 4 266 29.7 4.32 HVO_0322 MinD/ParA domain protein 12.39 1 4 4 29 6.550E8 15.87 12.39 4 14 1237.98 12.39 4 15 581 58.8 3.70 HVO_B0115 fumarylacetoacetase family protein 12.37 1 3 3 12 6.128E8 8.27 12.37 3 6 679.86 12.37 3 6 283 30.3 4.21 HVO_1083 glucose 1-dehydrogenase 12.32 1 3 3 7 5.890E7 7.15 12.32 3 3 411.63 12.32 3 4 357 39.0 4.73 HVO_1716 7-cyano-7-deazaguanine synthase 12.30 1 3 3 10 1.810E8 3.35 12.30 3 5 323.59 12.30 3 5 244 26.8 4.42 HVO_B0116 probable oxidoreductase (short-chain dehydrogenase family) 12.08 1 2 2 6 1.317E8 2.50 12.08 2 3 168.67 12.08 2 3 265 28.0 4.53 HVO_1174 transcription initiation factor TFE 11.93 1 2 2 3 1.353E8 258.98 11.93 2 3 176 20.6 4.23 HVO_0179 Lrp/AsnC family transcription regulator / TrkA domain protein 11.88 1 2 2 6 1.645E8 2.10 11.88 2 3 195.41 11.88 2 3 261 28.0 4.58 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 11.87 1 4 4 17 1.481E8 9.47 11.87 4 8 929.03 11.87 4 9 379 41.7 4.83 HVO_2610 deoxyribose-phosphate aldolase 11.79 1 2 2 14 2.024E8 9.68 11.79 2 7 666.40 11.79 2 7 212 21.9 4.23 HVO_0228 ParA domain protein 11.74 1 2 2 4 4.845E8 425.38 11.74 2 4 247 24.6 4.16 HVO_1279 dihydrofolate reductase 11.73 1 2 2 7 4.859E7 0.00 11.73 2 3 192.50 11.73 2 4 162 18.0 4.58 HVO_A0153 UspA domain protein 11.73 1 2 2 6 6.697E7 1.72 11.73 2 3 229.87 11.73 2 3 162 17.4 4.97 HVO_0687 M20 family amidohydrolase 11.71 1 4 4 16 1.256E8 16.49 11.71 4 8 1240.34 11.71 4 8 444 47.5 4.58 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 12 7.203E8 11.83 11.64 2 6 995.40 11.64 2 6 189 20.3 4.22 HVO_0795 transcription initiation factor TFB 11.64 1 3 3 6 2.763E8 0.00 11.64 3 3 159.33 11.64 3 3 335 37.4 5.59 HVO_B0345 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 11.64 1 2 2 3 5.624E7 126.25 11.64 2 3 378 41.2 4.84 HVO_0431 HAD superfamily hydrolase 11.62 1 2 2 3 8.323E7 5.04 11.62 2 3 284 30.4 4.26 HVO_2250 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 11.60 1 2 2 8 1.635E8 0.00 11.60 2 4 323.05 11.60 2 4 181 19.5 4.28 HVO_A0332 IclR family transcription regulator 11.54 1 1 2 3 3.520E7 4.27 11.54 2 3 260 28.7 5.05 HVO_B0146 aminotransferase class V 11.41 1 3 3 8 2.927E8 0.00 11.41 3 4 216.53 11.41 3 4 377 41.2 4.93 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 11.40 1 4 4 21 8.677E8 17.83 11.40 4 11 1229.93 10.47 3 10 430 44.2 4.37 HVO_B0179 YfiH family protein 11.32 1 2 2 8 1.289E7 0.00 11.32 2 4 117.20 11.32 2 4 265 29.2 5.35 HVO_1117 HTH-10 family transcription regulator 11.27 1 3 3 7 2.851E7 0.00 11.27 3 4 276.68 6.57 2 3 213 23.3 4.56 HVO_0475 conserved hypothetical protein 11.22 1 2 2 5 6.670E7 0.00 11.22 2 3 85.98 11.22 2 2 312 32.5 4.74 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 11.22 1 5 5 18 1.234E8 5.48 11.22 5 9 754.78 11.22 5 9 410 46.0 4.89 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 11.22 1 3 3 12 4.411E8 7.39 11.22 3 6 459.08 11.22 3 6 401 43.1 4.60 HVO_2456 anthranilate phosphoribosyltransferase 11.18 1 2 2 12 8.662E8 9.39 11.18 2 6 760.43 11.18 2 6 331 33.8 4.35 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 11.15 1 3 3 6 2.074E8 8.58 11.15 3 3 470.18 11.15 3 3 574 62.8 4.17 HVO_1041 probable metallo-beta-lactamase family hydrolase 11.14 1 2 2 2 8.706E7 0.00 11.14 2 2 332 35.8 4.73 HVO_2530 homolog to phosphoribosylamine--glycine ligase 11.14 1 4 4 8 8.824E7 4.05 8.41 3 4 307.93 9.32 3 4 440 49.8 4.70 HVO_1928 5-formyltetrahydrofolate cyclo-ligase 11.11 1 2 2 4 1.000E8 4.28 11.11 2 2 181.96 11.11 2 2 243 26.5 4.69 HVO_1038 uracil-DNA glycosylase superfamily protein 11.06 1 2 2 4 8.366E7 1.78 11.06 2 2 125.20 11.06 2 2 208 22.7 4.61 HVO_A0150 TrmB family transcription regulator 11.02 1 4 4 12 3.129E8 9.64 11.02 4 6 581.79 11.02 4 6 354 39.0 4.63 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 11.00 1 3 3 10 5.292E7 3.87 11.00 3 5 428.82 11.00 3 5 400 44.2 4.32 HVO_2056 "probable epimerase (homolog to dTDP-4-dehydrorhamnose 3,5-epimerase)" 10.90 1 2 2 2 2.897E7 196.83 10.90 2 2 156 18.3 4.55 HVO_1424 conserved hypothetical protein 10.86 1 3 3 10 1.915E8 2.08 10.86 3 5 336.00 10.86 3 5 359 40.9 4.60 HVO_B0202 sensor box protein 10.86 1 2 2 6 6.478E7 4.45 10.86 2 3 279.96 10.86 2 3 304 33.5 4.92 HVO_1077 diphthamide biosynthesis protein Dph6 10.83 1 2 2 7 1.240E8 3.54 10.83 2 3 407.67 10.83 2 4 240 26.0 4.15 HVO_A0635 probable cysteine desulfurase 10.78 1 2 2 7 1.077E8 0.00 10.78 2 4 172.68 10.78 2 3 371 40.4 4.53 HVO_C0054 hypothetical protein 10.76 1 2 2 8 1.138E8 6.93 10.76 2 4 480.59 10.76 2 4 344 37.5 4.70 HVO_1864 molybdopterin synthase catalytic subunit 10.73 1 3 3 8 1.604E8 3.65 10.73 3 5 265.75 6.51 2 3 261 27.9 4.41 HVO_0561 50S ribosomal protein L15e 10.71 1 2 2 6 3.704E7 2.52 10.71 2 3 295.70 10.71 2 3 196 22.5 11.15 HVO_1169 "probable glycosyltransferase, type 1" 10.60 1 3 3 6 5.721E7 4.55 10.60 3 3 161.04 10.60 3 3 368 40.8 4.73 HVO_2809 succinate dehydrogenase subunit B (iron-sulfur protein) 10.58 1 1 2 2 2.213E8 0.00 10.58 2 2 293 33.9 5.27 HVO_2812 AstE family protein 10.56 1 3 3 10 9.354E7 2.69 10.56 3 5 393.84 10.56 3 5 341 37.3 5.14 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 10.55 1 2 2 3 5.902E7 0.00 10.55 2 3 237 26.2 4.70 HVO_0682 probable Mrr family endonuclease 10.48 1 2 2 4 1.973E8 0.00 10.48 2 2 101.41 10.48 2 2 334 36.3 4.83 HVO_2306 receiver box response regulator 10.48 1 2 2 6 1.314E8 7.13 10.48 2 3 288.63 10.48 2 3 248 26.5 4.13 HVO_2485 biotin--[acetyl-CoA-carboxylase] ligase 10.48 1 2 2 4 1.945E8 4.11 10.48 2 4 334 35.7 4.75 HVO_B0127 oxidoreductase (luciferase family protein) 10.41 1 4 4 8 7.209E7 2.04 8.52 3 3 322.53 10.41 4 5 317 35.7 4.60 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 10.37 1 3 3 8 4.950E7 2.13 10.37 3 4 281.14 10.37 3 4 328 36.1 4.67 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 10.36 1 4 4 16 1.715E8 5.38 10.36 4 8 740.15 10.36 4 8 386 40.0 4.68 HVO_1058 TrkA domain protein 10.34 1 4 4 18 3.580E8 9.80 10.34 4 9 756.11 10.34 4 9 445 47.7 4.35 HVO_0042 acetylornithine deacetylase 10.24 1 3 3 12 5.346E8 12.05 10.24 3 6 765.73 10.24 3 6 381 41.0 4.34 HVO_1656 YyaL family protein 10.24 1 7 7 21 1.395E8 8.24 10.24 7 10 815.02 10.24 7 11 703 77.3 4.49 HVO_B0183 YgeA family protein 10.20 1 3 3 12 9.548E7 3.37 10.20 3 6 556.17 10.20 3 6 245 26.8 4.58 HVO_0522 HdaI-type histone deacetylase 10.09 1 2 2 10 1.168E8 16.62 10.09 2 5 990.34 10.09 2 5 337 36.3 4.45 HVO_1341 "2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase" 10.05 1 2 2 4 4.740E7 0.00 10.05 2 2 103.48 10.05 2 2 219 23.0 4.56 HVO_2131 "fructose-1,6-bisphosphatase" 10.03 1 2 2 4 2.858E7 3.15 10.03 2 2 295.17 10.03 2 2 289 31.3 4.48 HVO_0719 transcription elongation factor Spt5/NusG 10.00 1 2 2 4 1.419E8 323.84 10.00 2 4 150 16.3 4.50 HVO_1936 F420-0:gamma-glutamyl ligase 9.96 1 2 2 6 1.012E8 2.28 9.96 2 3 254.88 9.96 2 3 251 27.4 4.68 HVO_0464 threonine ammonia-lyase 9.93 1 3 3 8 1.318E8 2.38 9.93 3 4 293.51 9.93 3 4 403 43.7 4.72 HVO_0979 NADH dehydrogenase-like complex subunit B 9.87 1 2 2 7 1.099E8 3.70 9.87 2 3 305.31 9.87 2 4 233 26.1 5.01 HVO_2153 probable copper-containing oxidoreductase 9.87 1 3 3 10 1.265E8 11.67 9.87 3 5 846.76 9.87 3 5 385 42.1 5.82 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 9.84 1 3 3 8 1.323E8 3.61 9.84 3 4 300.08 9.84 3 4 437 47.1 4.72 HVO_1537 Orc1-type DNA replication protein 9.75 1 3 3 6 5.713E7 1.72 9.75 3 3 170.56 9.75 3 3 400 42.4 5.52 HVO_0029 UvrABC system protein B 9.60 1 6 6 14 1.517E8 2.16 8.02 5 6 651.57 9.60 6 8 698 79.0 4.45 HVO_2356 GNAT family acetyltransferase 9.58 1 3 3 6 7.920E7 1.83 9.58 3 3 319.44 9.58 3 3 407 45.1 4.64 HVO_B0029 xylose dehydrogenase (NADP) 9.54 1 3 3 10 7.273E7 4.20 9.54 3 5 330.48 9.54 3 5 325 34.7 4.39 HVO_2363 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 9.52 1 2 2 4 6.028E7 3.42 9.52 2 2 170.84 9.52 2 2 273 27.6 4.40 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 9.52 1 2 2 14 1.913E8 6.40 9.52 2 7 595.72 9.52 2 7 189 21.7 4.46 HVO_1314 5'-nucleotidase SurE 9.51 1 2 2 2 3.349E7 86.73 9.51 2 2 263 27.8 4.48 HVO_1650 polyphosphate kinase 9.50 1 6 6 20 1.423E8 11.07 9.50 6 10 985.94 9.50 6 10 832 93.6 4.65 HVO_2501 alpha/beta hydrolase fold protein 9.49 1 2 2 8 6.847E7 6.91 9.49 2 4 338.39 9.49 2 4 316 35.3 5.72 HVO_B0031 probable oxidoreductase (short-chain dehydrogenase family) 9.49 1 2 2 2 3.007E8 0.00 9.49 2 2 253 27.0 4.55 HVO_2636 PspA domain protein 9.42 1 2 2 10 5.320E7 8.69 9.42 2 5 497.88 9.42 2 5 276 30.9 4.61 HVO_C0067 FAD-dependent oxidoreductase 9.34 1 4 4 16 2.744E8 10.71 9.34 4 8 789.81 9.34 4 8 396 42.7 4.30 HVO_0648 DUF2070 family protein 9.26 1 2 2 2 4.607E8 0.00 9.26 2 2 637 67.7 4.77 HVO_2510 GNAT family acetyltransferase 9.21 1 2 2 4 3.091E7 1.70 9.21 2 2 72.15 9.21 2 2 304 33.7 4.49 HVO_2297 deoxyhypusine synthase 9.19 1 3 3 11 1.717E8 0.00 9.19 3 6 250.15 9.19 3 5 359 38.6 4.59 HVO_2183 aldehyde ferredoxin oxidoreductase 9.18 1 4 4 9 6.185E7 4.29 7.00 3 4 345.87 9.18 4 5 643 69.3 4.59 HVO_2932 GTP-binding protein 9.09 1 3 3 10 1.788E8 4.87 9.09 3 5 427.33 9.09 3 5 396 43.5 4.51 HVO_0824 "probable glycosyltransferase, type 1" 9.09 1 3 3 3 3.473E7 126.44 9.09 3 3 352 39.6 5.08 HVO_2873 flap endonuclease Fen1 8.90 1 3 3 7 5.678E7 4.55 8.90 3 4 368.56 5.83 2 3 326 36.4 4.40 HVO_0716 D-tyrosyl-tRNA(Tyr) deacylase 8.88 1 3 3 5 3.620E7 0.00 8.88 3 3 49.22 6.83 2 2 439 46.7 4.48 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 8.78 1 3 4 10 8.149E7 2.52 8.78 4 5 476.05 6.76 3 5 444 47.1 4.77 HVO_A0591 DICT domain protein 8.70 1 2 2 6 8.084E7 2.18 8.70 2 3 302.94 8.70 2 3 253 27.8 4.50 HVO_1501 DeoR family transcription regulator GlpR 8.63 1 2 2 6 8.721E7 3.24 8.63 2 4 198.49 8.63 2 2 255 28.0 4.97 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 8.61 1 1 2 8 2.919E8 8.31 8.61 2 4 534.74 8.61 2 4 267 28.8 4.55 HVO_0311 A-type ATP synthase subunit I 8.59 1 4 4 12 1.842E8 1.76 8.59 4 6 363.63 8.59 4 6 733 79.5 4.41 HVO_0569 RIO-type serine/threonine protein kinase 8.58 1 2 2 4 7.601E7 2.43 8.58 2 2 174.84 8.58 2 2 303 34.4 4.94 HVO_0639 AAA-type ATPase (MoxR subfamily) 8.54 1 2 2 7 7.529E7 0.00 8.54 2 3 269.45 8.54 2 4 316 34.7 4.89 HVO_1087 UspA domain protein 8.51 1 2 2 8 2.083E8 9.01 8.51 2 4 525.10 8.51 2 4 141 15.2 4.98 HVO_0590 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase 8.45 1 2 2 2 6.144E7 66.29 8.45 2 2 355 35.6 4.30 HVO_1344 SBDS family protein 8.40 1 2 2 6 4.120E7 6.13 8.40 2 3 390.47 8.40 2 3 238 26.5 4.51 HVO_2071 conserved hypothetical protein 8.38 1 4 4 19 2.588E8 17.20 8.38 4 10 1154.53 8.38 4 9 549 58.4 4.72 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 8.33 1 4 4 10 2.493E8 0.00 8.33 4 5 320.02 8.33 4 5 492 52.1 4.83 HVO_B0038A D-xylonate dehydratase 8.25 1 1 3 18 6.980E8 8.71 8.25 3 9 842.16 8.25 3 9 412 45.5 4.55 HVO_2648 phosphoglycerate dehydrogenase 8.15 1 2 2 6 2.768E8 2.44 8.15 2 3 245.84 8.15 2 3 319 34.2 4.64 HVO_2911 deoxyribodipyrimidine photolyase 8.06 1 3 3 6 2.969E7 2.34 8.06 3 3 223.39 8.06 3 3 484 54.5 4.79 HVO_B0069 aldehyde dehydrogenase 8.06 1 2 2 5 3.999E7 0.00 8.06 2 3 112.67 8.06 2 2 459 50.1 4.74 HVO_2697 DNA primase small subunit 8.05 1 3 3 7 3.890E7 4.02 6.23 2 3 405.75 8.05 3 4 385 42.6 4.72 HVO_0568 TrmB family transcription regulator 8.02 1 2 2 6 2.637E7 3.87 8.02 2 3 210.86 8.02 2 3 349 38.3 4.56 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 7.98 1 2 2 7 1.501E8 5.06 7.98 2 4 340.14 7.98 2 3 376 41.8 4.91 HVO_0968 NADH dehydrogenase-like complex subunit CD 7.98 1 0 4 22 1.208E9 19.87 7.98 4 11 1355.73 7.98 4 11 564 63.3 4.60 HVO_1447 propionyl-CoA carboxylase carboxyltransferase component 7.92 1 3 3 11 9.769E7 11.54 7.92 3 5 475.60 7.92 3 6 581 63.6 4.70 HVO_C0057 Orc1-type DNA replication protein 7.89 1 3 3 6 7.163E7 2.64 7.89 3 3 269.92 7.89 3 3 418 46.3 5.02 HVO_A0180 SMC-like protein Sph1 7.76 1 3 4 10 1.534E8 3.68 7.76 4 6 312.35 6.91 3 4 593 66.4 4.58 HVO_A0001 Orc1-type DNA replication protein 7.69 1 3 3 3 5.272E7 107.91 7.69 3 3 416 47.0 4.97 HVO_1594 tRNA/rRNA cytosine-C5-methylase 7.67 1 2 2 6 2.068E8 4.15 7.67 2 3 255.84 7.67 2 3 313 34.6 4.69 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 7.63 1 0 4 12 3.519E8 6.00 7.63 4 6 611.28 7.63 4 6 472 51.6 5.16 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 7.61 1 0 4 12 3.519E8 6.00 7.61 4 6 611.28 7.61 4 6 473 51.2 5.05 HVO_1888 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfate/tungstate) 7.60 1 2 2 6 3.502E7 5.26 7.60 2 3 322.05 7.60 2 3 342 35.9 4.34 HVO_1940 DNA mismatch repair protein MutS 7.60 1 5 5 12 4.478E7 7.37 7.60 5 6 619.60 7.60 5 6 921 99.4 4.42 HVO_B0100 aldehyde dehydrogenase 7.45 1 3 3 6 7.040E7 2.58 7.45 3 3 218.11 7.45 3 3 483 50.4 4.31 HVO_A0439 DUF2800 family protein 7.36 1 2 2 2 3.229E7 0.00 7.36 2 2 326 36.9 4.51 HVO_2004 serine O-acetyltransferase 7.32 1 1 2 8 1.555E9 3.93 7.32 2 4 339.26 7.32 2 4 287 31.9 5.21 HVO_1456 receiver/sensor box histidine kinase 7.31 1 1 2 3 1.471E8 242.27 7.31 2 3 506 53.8 4.70 HVO_0771 probable metallo-beta-lactamase family hydrolase 7.25 1 2 2 2 2.538E8 0.00 7.25 2 2 262 27.7 6.47 HVO_0135 RIO-type serine/threonine protein kinase 7.24 1 2 2 8 1.390E8 10.19 7.24 2 4 665.24 7.24 2 4 290 33.0 4.81 HVO_B0233 alpha-L-arabinofuranosidase 7.24 1 3 3 13 8.503E7 10.23 7.24 3 7 544.29 7.24 3 6 511 57.5 4.39 HVO_B0216 UPF0261 family protein 7.20 1 2 2 4 7.840E7 2.60 7.20 2 2 222.33 7.20 2 2 403 42.4 4.34 HVO_0826 peptidase M42 family protein 7.18 1 2 2 8 1.701E8 7.44 7.18 2 4 441.92 7.18 2 4 348 37.7 4.54 HVO_1615 conserved hypothetical protein 7.17 1 2 2 4 5.970E7 1.97 7.17 2 2 193.65 7.17 2 2 251 28.4 4.59 HVO_0073 single-stranded-DNA-specific exonuclease RecJ1 7.14 1 3 3 8 8.349E7 2.28 7.14 3 4 208.86 7.14 3 4 476 50.6 4.68 HVO_1047 NADPH:quinone reductase 7.12 1 2 2 6 6.457E7 0.00 7.12 2 3 247.32 7.12 2 3 323 33.8 4.27 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 10 2.789E8 10.03 7.07 2 5 705.20 7.07 2 5 297 32.3 3.98 HVO_A0521 phenylacetyl-coenzyme A ligase 6.99 1 2 2 6 9.938E7 1.74 6.99 2 2 176.18 6.99 2 4 429 47.4 4.46 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 6.98 1 3 3 8 1.428E8 5.15 6.98 3 4 446.04 6.98 3 4 573 62.9 4.45 HVO_0724 ArsA family ATPase 6.85 1 2 2 6 5.491E7 7.95 6.85 2 3 411.86 6.85 2 3 409 43.9 4.22 HVO_0191 DNA mismatch repair protein MutS 6.78 1 4 4 11 4.341E7 6.48 6.78 4 5 418.19 6.78 4 6 664 70.7 4.46 HVO_1470 isochorismate synthase 6.77 1 3 3 14 9.085E7 3.66 6.77 3 8 476.05 6.77 3 6 443 47.7 4.56 HVO_1419 HTH-10 family transcription regulator 6.67 1 2 2 6 5.565E7 0.00 6.67 2 3 241.97 6.67 2 3 225 25.2 4.77 HVO_1008 GFO family oxidoreductase 6.63 1 2 2 8 1.580E8 8.85 6.63 2 4 537.93 6.63 2 4 332 36.0 4.72 HVO_1301 conserved hypothetical protein 6.63 1 3 3 6 1.220E8 0.00 3.91 2 3 115.20 6.63 3 3 588 63.4 4.68 HVO_0757 probable oxidoreductase (aldo-keto reductase family protein) 6.61 1 2 2 4 8.329E7 0.00 6.61 2 2 98.49 6.61 2 2 363 39.1 4.77 HVO_C0074 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 6.52 1 4 4 12 7.454E7 12.62 6.52 4 6 758.34 6.52 4 6 690 75.9 4.79 HVO_A0159 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 6.46 1 2 2 6 1.441E8 2.20 6.46 2 3 265.25 6.46 2 3 387 42.7 4.44 HVO_2665 HpcH/HpaI aldolase family protein 6.42 1 2 2 3 5.747E7 174.40 6.42 2 3 265 28.3 4.50 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 6.29 1 5 5 13 1.471E8 4.15 6.29 5 7 482.21 5.13 4 6 858 93.9 4.69 HVO_A0562 urocanate hydratase 6.29 1 3 3 14 9.482E7 14.57 6.29 3 7 819.10 6.29 3 7 620 67.9 4.70 HVO_1735 conserved hypothetical protein 6.21 1 4 4 14 5.738E7 6.36 6.21 4 7 712.10 6.21 4 7 660 75.7 4.50 HVO_2448 probable oxidoreductase (aldo-keto reductase family protein) 6.12 1 2 2 8 8.210E7 1.62 6.12 2 4 223.94 6.12 2 4 327 36.5 4.94 4557890 keratin 5 [Homo sapiens] 6.10 1 0 4 21 1.912E8 14.00 6.10 4 10 1066.35 6.10 4 11 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 6.10 1 0 4 21 1.912E8 14.00 6.10 4 10 1066.35 6.10 4 11 590 62.4 8.06 HVO_2860 conserved hypothetical protein 6.05 1 3 3 10 9.473E7 2.27 6.05 3 5 577.00 6.05 3 5 562 58.9 4.49 HVO_2058 NAD-dependent epimerase/dehydratase (homolog to dTDP-4-dehydrorhamnose reductase) 6.00 1 2 2 6 7.211E8 5.91 6.00 2 3 407.26 6.00 2 3 300 32.0 4.22 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 5.95 1 2 2 6 3.426E8 2.20 5.95 2 3 278.17 5.95 2 3 353 36.7 4.65 HVO_1565 DNA ligase (ATP) 5.81 1 3 3 8 1.402E8 4.95 4.27 2 3 494.79 5.81 3 5 585 62.7 4.44 HVO_1596 DUF790 family protein 5.80 1 2 2 6 5.372E7 2.31 5.80 2 3 241.78 5.80 2 3 500 53.9 4.65 HVO_1351 DNA repair helicase Rad3 5.74 1 2 2 2 5.127E7 0.00 5.74 2 2 784 85.8 4.58 18031720 keratin protein K6irs [Homo sapiens] 5.69 1 0 3 8 9.611E7 2.16 3.53 2 3 329.72 5.69 3 5 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 5.68 1 0 3 8 9.611E7 2.16 3.52 2 3 329.72 5.68 3 5 511 55.8 6.89 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 5.64 1 2 2 6 5.680E7 6.21 5.64 2 3 333.29 5.64 2 3 337 35.9 4.39 HVO_2311 glutamyl-tRNA reductase 5.64 1 3 3 5 4.895E7 3.97 5.64 3 3 145.83 3.47 2 2 461 49.2 4.54 HVO_2640 conserved hypothetical protein 5.50 1 2 2 2 3.138E7 117.41 5.50 2 2 309 33.9 4.56 HVO_1113 "FtsZ family protein, type III" 5.40 1 0 2 6 1.270E9 2.08 5.40 2 3 366.75 5.40 2 3 389 40.8 4.89 HVO_1651 thiamine / thiouridine biosynthesis protein ThiI 5.37 1 2 2 4 2.932E7 0.00 5.37 2 2 136.29 5.37 2 2 391 41.7 4.82 HVO_2832 conserved hypothetical protein (nonfunctional) 5.37 1 2 2 2 7.271E5 86.66 5.37 2 2 298 33.6 4.72 HVO_A0209 CRISPR-associated helicase Cas3 5.34 1 4 4 7 4.619E7 2.09 5.34 4 4 179.21 4.16 3 3 937 103.6 4.93 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 5.28 1 2 2 2 1.235E8 3.03 5.28 2 2 398 43.4 4.37 HVO_C0050 conserved hypothetical protein 5.26 1 2 2 2 3.012E7 143.50 5.26 2 2 266 30.7 4.59 HVO_2872 conserved hypothetical protein 5.24 1 2 2 2 9.534E7 103.93 5.24 2 2 458 50.8 4.81 HVO_0634 Orc1-type DNA replication protein 5.15 1 2 2 8 8.719E7 0.00 5.15 2 4 294.53 5.15 2 4 408 45.6 4.65 HVO_A0537 N-methylhydantoinase (ATP-hydrolyzing) A 5.07 1 3 3 8 3.664E7 6.85 5.07 3 4 410.83 5.07 3 4 671 70.0 4.56 HVO_1668 gamma-glutamylcysteine synthetase 5.03 1 2 2 6 3.460E7 1.60 5.03 2 3 271.05 5.03 2 3 358 39.9 4.72 HVO_0477 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 5.02 1 2 2 2 3.708E8 157.19 5.02 2 2 319 33.4 4.18 HVO_0710 aminodeoxychorismate synthase component II 4.96 1 2 2 2 7.769E7 0.00 4.96 2 2 504 54.6 4.53 HVO_2175 SMC-like protein Sph3 4.89 1 3 3 4 4.418E7 0.00 2.75 2 2 45.72 3.21 2 2 654 74.2 4.54 HVO_1917 acyl-CoA synthetase 4.80 1 3 3 8 6.996E7 7.69 4.80 3 4 384.92 4.80 3 4 666 74.0 4.78 HVO_C0041 conserved hypothetical protein 4.67 1 2 2 2 4.778E7 139.60 4.67 2 2 835 94.5 5.06 HVO_1228 halocyanin 4.63 1 3 3 10 1.528E8 6.28 4.63 3 5 545.09 4.63 3 5 821 83.7 4.17 HVO_2080 conserved hypothetical protein 4.63 1 2 2 10 5.269E7 9.72 4.63 2 5 528.65 4.63 2 5 540 57.0 4.30 21961227 Keratin 6B [Homo sapiens] 4.61 1 0 3 25 2.589E8 19.71 4.61 3 12 1398.08 4.61 3 13 564 60.0 8.00 HVO_0783 ATP-dependent protease La 4.61 1 2 2 3 4.447E7 175.60 4.61 2 3 694 75.4 4.86 HVO_2381 UPF0272 family protein 4.46 1 2 2 6 9.666E7 4.26 4.46 2 3 278.98 4.46 2 3 493 52.3 4.88 HVO_B0257 4-aminobutyrate aminotransferase 4.36 1 2 2 4 3.360E7 0.00 4.36 2 2 137.84 4.36 2 2 459 49.3 4.92 HVO_2598 polyphosphate kinase 4.28 1 2 2 8 4.519E7 4.11 4.28 2 4 207.72 4.28 2 4 747 83.6 5.11 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 4.17 1 0 2 17 2.326E8 12.29 4.17 2 8 958.00 4.17 2 9 384 42.4 5.40 HVO_0003 DNA-directed DNA polymerase D exonuclease subunit DP1 4.13 1 2 2 6 5.398E7 2.21 4.13 2 3 178.22 4.13 2 3 533 57.8 4.77 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 4.01 1 3 3 9 9.336E7 3.97 2.12 2 4 357.88 4.01 3 5 898 97.7 4.45 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 4.00 1 0 2 6 4.873E8 2.15 4.00 2 3 274.56 4.00 2 3 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 4.00 1 0 2 6 4.873E8 2.15 4.00 2 3 274.56 4.00 2 3 400 44.1 5.14 HVO_2275 N-6 adenine-specific DNA methylase domain protein 3.75 1 2 2 2 2.739E7 2.10 3.75 2 2 853 97.1 4.49 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 3.70 1 0 2 6 4.873E8 2.15 3.70 2 3 274.56 3.70 2 3 432 48.1 5.02 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 3.51 1 0 2 6 4.873E8 2.15 3.51 2 3 274.56 3.51 2 3 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 3.51 1 0 2 6 4.873E8 2.15 3.51 2 3 274.56 3.51 2 3 456 49.2 4.77 15618995 keratin 6 irs [Homo sapiens] 3.44 1 0 2 7 1.333E8 2.16 3.44 2 3 305.81 3.44 2 4 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.40 1 0 2 7 1.333E8 2.16 3.40 2 3 305.81 3.40 2 4 529 57.8 7.71 HVO_B0093 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 3.40 1 2 2 3 2.242E7 3.37 3.40 2 3 618 69.1 4.45 28173564 keratin 6 irs3 [Homo sapiens] 3.33 1 0 2 7 1.333E8 2.16 3.33 2 3 305.81 3.33 2 4 540 58.9 7.23 HVO_A0254 DUF234 domain protein 3.25 1 2 2 2 6.869E7 149.91 3.25 2 2 461 52.7 4.78 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 2.84 1 0 2 17 2.326E8 12.29 2.84 2 8 958.00 2.84 2 9 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 2.84 1 0 2 17 2.326E8 12.29 2.84 2 8 958.00 2.84 2 9 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 2.84 1 0 2 17 2.326E8 12.29 2.84 2 8 958.00 2.84 2 9 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 2.84 1 0 2 17 2.326E8 12.29 2.84 2 8 958.00 2.84 2 9 564 60.0 7.72 31074633 keratin 6L [Homo sapiens] 2.80 1 0 2 7 1.239E8 0.00 2.80 2 3 293.71 2.80 2 4 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 2.80 1 0 2 7 1.239E8 0.00 2.80 2 3 293.71 2.80 2 4 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 2.80 1 0 2 7 1.239E8 0.00 2.80 2 3 293.71 2.80 2 4 535 57.7 7.20 HVO_1697 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 2.73 1 2 2 2 8.309E7 133.43 2.73 2 2 1026 111.2 4.54 HVO_0039 DNA repair helicase Rad3 2.72 1 2 2 2 7.490E7 0.00 2.72 2 2 734 82.7 4.59 HVO_0065 DNA-directed DNA polymerase D large subunit 2.08 1 2 2 4 6.473E7 4.07 2.08 2 2 231.93 2.08 2 2 1202 133.9 4.60 HVO_2767 ATP-dependent DNA helicase Dna2 1.81 1 2 2 4 3.621E7 1.62 1.81 2 2 116.94 1.81 2 2 884 97.5 4.86