Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0329 branched-chain amino acid aminotransferase 76.92 1 21 21 116 3.276E9 110.89 76.60 20 58 7425.34 76.92 21 58 312 35.0 4.58 HVO_0359 translation elongation factor aEF-1 alpha subunit 76.25 1 18 22 1061 4.880E10 1008.69 71.97 21 499 75918.40 76.25 22 562 421 45.7 4.73 HVO_0433 F420H2:NADP oxidoreductase 76.13 1 10 10 48 1.120E9 51.72 76.13 10 25 3108.18 76.13 10 23 222 23.3 4.72 HVO_0356 translation elongation factor aEF-2 76.07 1 44 44 647 2.018E10 639.29 75.24 43 321 39122.99 76.07 44 326 727 80.4 4.73 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 75.49 1 16 16 175 7.570E9 176.68 75.49 16 89 11741.42 75.49 16 86 355 38.2 4.68 HVO_0880 conserved hypothetical protein 71.34 1 27 27 208 2.837E9 236.55 68.40 26 103 15094.53 71.34 27 105 307 36.3 4.74 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 68.57 1 16 16 141 5.087E9 135.88 68.57 16 67 9764.79 68.57 16 74 350 37.6 4.54 HVO_1921 serine--tRNA ligase 65.65 1 26 26 122 2.204E9 125.28 65.65 26 60 7988.05 65.65 26 62 460 52.0 4.46 HVO_2619 ubiquitin-like modifier protein SAMP1 62.07 1 3 3 3 9.435E7 103.90 62.07 3 3 87 8.9 4.26 HVO_0055 CBS domain protein 61.62 1 13 13 77 2.338E9 71.85 54.93 11 37 5124.19 61.62 13 40 284 30.8 4.27 HVO_2413 translation elongation factor aEF-1 alpha subunit 61.19 1 15 19 151 1.347E10 107.94 56.90 18 72 9492.84 61.19 19 79 420 45.6 4.75 HVO_0025 thiosulfate sulfurtransferase 60.84 1 11 11 183 1.578E10 136.07 60.84 11 90 9439.15 60.84 11 93 286 32.1 4.28 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 60.50 1 13 13 60 1.005E9 48.89 60.50 13 31 3471.11 60.50 13 29 281 30.6 4.59 HVO_2862 serine hydroxymethyltransferase 59.52 1 16 16 197 7.785E9 151.59 59.52 16 98 11760.62 59.52 16 99 415 44.3 4.53 HVO_2783 30S ribosomal protein S4 58.86 1 10 10 47 1.826E9 38.84 46.29 8 22 3202.93 58.86 10 25 175 20.1 5.24 HVO_0175 DNA polymerase sliding clamp 58.70 1 8 8 111 5.120E9 70.86 58.70 8 54 5678.02 58.70 8 57 247 26.7 4.39 HVO_1145 30S ribosomal protein S1e 58.18 1 12 12 68 1.973E9 63.53 58.18 12 35 4539.08 58.18 12 33 220 24.8 4.86 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 57.14 1 14 14 65 1.195E9 57.14 57.14 14 32 4549.63 57.14 14 33 343 38.4 4.94 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 56.96 1 14 14 163 9.935E9 140.07 56.96 14 81 9181.27 56.96 14 82 381 41.0 4.23 HVO_0118 50S ribosomal protein L20e 56.90 1 3 3 8 1.420E8 5.37 56.90 3 4 395.73 56.90 3 4 58 6.4 6.52 HVO_1273 inosine-5'-monophosphate dehydrogenase 56.83 1 18 18 179 4.168E9 154.74 54.22 17 89 11711.09 52.01 17 90 498 53.3 4.55 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 56.77 1 15 15 141 5.137E9 179.12 56.77 15 69 11385.73 56.77 15 72 384 41.4 4.41 HVO_0348 DNA-directed RNA polymerase subunit B' 56.65 1 25 25 161 1.922E9 164.32 56.65 25 80 10149.01 51.07 24 81 609 67.7 4.92 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 56.46 1 16 16 79 1.186E9 54.28 56.46 16 39 4433.42 56.46 16 40 457 48.4 4.35 HVO_0400 conserved hypothetical protein 56.35 1 4 4 10 1.729E8 2.31 56.35 4 5 232.93 56.35 4 5 126 13.9 4.68 HVO_0861 SufB domain protein 55.97 1 16 16 110 3.253E9 100.36 52.49 15 56 8028.29 53.48 15 54 402 44.7 4.23 HVO_1454 aspartate carbamoyltransferase catalytic subunit 55.92 1 11 11 40 5.277E8 39.26 53.29 10 20 2390.27 55.92 11 20 304 33.7 4.92 HVO_0870 proline--tRNA ligase 55.74 1 19 19 102 1.780E9 94.38 52.05 16 49 6387.03 55.74 19 53 488 54.9 4.44 HVO_0778 thermosome subunit 3 55.53 1 21 23 186 3.079E9 198.80 50.95 21 92 12907.08 55.53 23 94 524 55.2 4.59 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 54.81 1 11 11 133 6.089E9 118.60 54.81 11 68 8122.04 54.81 11 65 312 34.5 4.98 HVO_0240 Lrp/AsnC family transcription regulator 54.61 1 6 7 29 8.188E8 14.68 49.34 6 13 1577.95 54.61 7 16 152 16.9 4.39 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 54.35 1 8 8 28 5.429E8 27.13 48.91 7 12 2298.78 54.35 8 16 184 19.8 5.30 HVO_2588 isocitrate dehydrogenase (NADP) 53.94 1 21 21 196 9.211E9 185.67 50.84 20 96 12367.15 53.94 21 100 419 45.8 4.59 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 53.38 1 23 23 124 5.384E9 103.48 51.35 21 60 8036.60 53.38 23 64 592 66.6 4.61 HVO_2191 formyltetrahydrofolate deformylase 53.21 1 14 14 50 1.934E9 55.73 53.21 14 25 3592.21 53.21 14 25 327 36.2 4.63 HVO_2889 RecJ domain protein 52.95 1 27 27 177 4.872E9 148.36 52.95 27 89 10427.39 49.52 26 88 729 79.1 4.37 HVO_2969 threonine synthase 52.27 1 16 16 91 2.418E9 80.57 45.58 15 45 5346.75 52.27 16 46 419 44.4 4.49 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 51.82 1 13 13 90 4.022E9 74.88 44.55 12 44 5574.31 51.82 13 46 413 45.8 4.45 HVO_2900 fumarate hydratase 51.81 1 15 15 120 5.970E9 118.22 51.81 15 61 7510.11 51.81 15 59 469 50.1 4.78 HVO_2724 beta-lactamase domain protein 51.56 1 18 18 131 3.546E9 100.03 51.56 17 65 7684.84 51.56 18 66 450 50.1 5.40 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 51.48 1 14 14 74 3.257E9 59.32 46.56 12 34 4971.00 51.48 14 40 305 33.8 4.74 HVO_2384 CBS domain protein 51.32 1 16 16 136 4.514E9 100.98 48.68 14 67 7627.04 51.32 16 69 380 42.5 5.01 HVO_A0207 CRISPR-associated protein Cas7 51.18 1 9 9 61 1.860E9 66.34 51.18 9 30 4164.61 51.18 9 31 340 38.2 4.54 HVO_0455 thermosome subunit 2 51.17 1 22 23 231 3.499E9 170.94 51.17 23 115 12185.71 51.17 23 116 557 59.3 4.37 HVO_0677 aspartate--tRNA ligase 51.15 1 16 16 200 8.381E9 197.43 51.15 16 101 12636.53 51.15 16 99 434 48.7 4.50 HVO_0317 A-type ATP synthase subunit B 50.85 1 15 16 112 5.783E9 132.66 48.08 15 54 8647.79 50.85 16 58 468 51.9 4.25 HVO_0581 "cell division protein FtsZ, type II" 50.75 1 13 13 64 1.553E9 69.89 43.50 12 32 4831.64 50.75 13 32 400 42.5 4.75 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 14 5.399E8 1.84 26.80 3 6 441.36 50.33 5 8 153 16.9 4.21 HVO_1502 3-isopropylmalate dehydrogenase 50.31 1 12 12 70 1.871E9 57.73 42.59 11 33 5194.74 50.31 12 37 324 33.7 4.23 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 50.30 1 10 10 56 1.224E9 53.80 38.39 8 26 4147.80 50.30 10 30 336 36.8 4.12 HVO_2015 conserved hypothetical protein 50.14 1 12 12 176 1.390E10 192.12 50.14 12 88 12897.51 50.14 12 88 345 37.7 4.25 HVO_0212 homolog to lactoylglutathione lyase 50.00 1 4 4 20 4.151E8 18.72 50.00 4 10 1433.07 50.00 4 10 124 13.5 4.13 HVO_1132 adenylosuccinate synthase 49.89 1 20 20 202 6.341E9 149.20 46.73 19 99 10565.09 46.05 18 103 443 48.2 4.56 HVO_2204 "FtsZ family protein, type III" 49.87 1 13 16 78 2.457E9 70.64 46.08 13 37 5098.16 49.87 16 41 395 42.0 4.68 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 49.48 1 6 6 28 1.172E9 22.10 38.66 4 11 2047.43 49.48 6 17 194 20.7 4.12 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 49.42 1 22 22 88 1.512E9 112.54 49.42 22 44 7333.57 49.42 22 44 599 65.3 4.51 HVO_0203 replication factor C small subunit 49.24 1 13 13 63 8.372E8 53.73 49.24 13 32 3761.72 49.24 13 31 327 36.2 4.51 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 49.12 1 14 14 58 5.984E8 51.79 47.35 13 29 3650.10 49.12 13 29 340 38.8 4.58 HVO_0999 DRTGG domain protein 48.94 1 13 13 54 1.101E9 42.35 48.94 13 26 3090.09 48.94 13 28 378 39.8 4.44 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 48.79 1 9 9 114 3.910E9 133.37 45.67 8 55 9237.54 48.79 9 59 289 29.8 4.27 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 48.54 1 13 13 54 1.199E9 49.05 48.54 13 27 3318.35 40.90 12 27 445 47.8 4.86 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 48.06 1 11 11 55 1.551E9 34.07 48.06 11 28 2701.71 48.06 11 27 360 39.6 4.39 HVO_0133 thermosome subunit 1 48.04 1 19 21 152 5.061E9 130.41 46.96 20 74 9525.68 48.04 21 78 560 58.9 4.25 HVO_0239 glutamine synthetase 48.03 1 16 16 87 3.258E9 70.06 48.03 15 44 4758.38 46.49 15 43 456 50.5 4.56 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 47.90 1 8 8 31 7.165E8 29.02 37.76 7 15 2006.26 47.90 8 16 286 31.2 4.54 HVO_2968 phosphoglycerate dehydrogenase 47.43 1 15 15 162 7.313E9 181.90 47.43 15 80 11654.22 47.43 15 82 525 55.3 4.36 HVO_0008 aspartate kinase 46.94 1 12 12 55 2.949E9 42.81 46.94 12 29 2969.93 36.48 10 26 392 41.7 4.46 HVO_2782 30S ribosomal protein S11 46.92 1 5 5 24 5.534E8 20.63 46.92 5 12 1375.27 46.92 5 12 130 13.4 8.56 HVO_2544 30S ribosomal protein S5 46.73 1 9 9 40 3.442E9 34.25 41.12 7 19 2833.31 46.73 9 21 214 23.3 9.29 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 46.69 1 9 9 109 3.428E9 109.16 46.69 9 54 7195.72 46.69 9 55 287 31.0 4.73 HVO_0602 3-dehydroquinate dehydratase 46.56 1 9 9 38 4.722E8 28.03 46.56 9 19 2357.19 46.56 9 19 247 27.3 4.51 HVO_2057 sugar nucleotidyltransferase 46.50 1 14 14 78 2.011E9 80.47 46.50 14 39 5283.83 46.50 14 39 357 37.8 4.44 HVO_2059 NAD-dependent epimerase/dehydratase 46.45 1 10 10 43 1.931E9 31.15 46.45 10 20 2638.94 46.45 10 23 310 34.1 4.40 HVO_0024 thiosulfate sulfurtransferase 45.74 1 9 9 39 1.320E9 26.95 36.05 7 18 2335.89 45.74 9 21 258 28.4 4.30 HVO_2487 aspartate-semialdehyde dehydrogenase 45.64 1 9 9 92 4.281E9 81.28 45.64 9 45 4527.95 45.64 9 47 344 36.6 4.41 HVO_2774 enolase 45.61 1 12 12 73 2.154E9 60.36 43.61 11 36 4592.46 45.61 12 37 399 42.0 4.37 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 45.56 1 21 21 184 6.472E9 190.26 43.69 20 92 12956.85 45.56 21 92 586 64.0 4.49 HVO_2558 30S ribosomal protein S3 45.39 1 11 11 111 4.354E9 103.24 41.12 10 53 7355.76 45.39 11 58 304 33.4 4.06 HVO_3007 malate dehydrogenase 45.39 1 12 12 189 8.730E9 180.92 45.39 12 93 10126.76 45.39 12 96 304 32.6 4.40 HVO_0316 A-type ATP synthase subunit A 45.22 1 20 20 124 4.391E9 112.14 45.22 20 62 7991.80 45.22 20 62 586 64.5 4.25 HVO_0347 DNA-directed RNA polymerase subunit B'' 45.11 1 21 21 138 1.971E9 94.10 43.76 20 69 8411.42 45.11 21 69 521 58.9 5.00 HVO_1338 replication protein A 44.96 1 12 12 38 6.083E8 22.47 44.96 12 19 2069.81 42.15 11 19 427 46.0 4.36 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 44.64 1 14 14 49 8.614E8 29.96 44.64 14 25 2454.65 44.64 14 24 336 38.0 4.61 HVO_2549 30S ribosomal protein S8 44.62 1 5 5 16 1.222E9 12.93 44.62 5 8 875.38 44.62 5 8 130 14.1 4.79 HVO_0869 glutamate synthase large subunit 44.61 1 49 50 265 2.046E9 276.58 43.28 49 132 18427.75 44.08 49 133 1511 163.8 4.70 HVO_2519 conserved hypothetical protein 44.50 1 12 12 53 1.320E9 55.79 39.79 11 26 3831.96 44.50 12 27 382 40.7 4.35 HVO_0989 conserved hypothetical protein 44.44 1 6 6 18 3.115E8 13.76 44.44 6 10 922.55 34.13 4 8 126 14.4 4.81 HVO_0449 prephenate dehydratase 44.40 1 9 9 43 1.131E9 42.28 44.40 9 21 2945.31 44.40 9 22 268 28.7 4.64 HVO_2646 dihydroxy-acid dehydratase 44.35 1 16 16 119 2.386E9 124.56 44.35 16 58 8209.95 44.35 16 61 584 61.8 4.42 HVO_1955 aconitate hydratase 44.34 1 23 23 310 1.479E10 308.98 43.58 22 153 20150.96 44.34 23 157 654 70.4 4.45 HVO_0850 proteasome-activating nucleotidase 44.20 1 12 13 66 1.412E9 47.56 44.20 13 34 3847.72 44.20 13 32 405 45.6 4.60 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 44.19 1 16 16 82 2.433E9 86.27 42.29 15 40 5454.21 44.19 15 42 525 56.4 4.40 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 44.15 1 19 19 85 1.411E9 57.88 44.15 18 43 4491.38 44.15 19 42 496 55.0 4.53 HVO_1080 conserved hypothetical protein 44.15 1 6 6 17 6.058E8 16.47 38.83 5 8 1153.42 44.15 6 9 188 21.1 4.31 HVO_0161 ATP phosphoribosyltransferase 44.13 1 10 10 46 1.032E9 48.25 44.13 10 24 2722.31 44.13 10 22 281 30.4 4.60 HVO_1189 aldehyde dehydrogenase 44.09 1 17 17 91 2.209E9 82.33 44.09 17 45 5407.61 44.09 17 46 508 56.1 4.59 HVO_0792 3-dehydroquinate synthase type II 43.62 1 14 14 66 1.315E9 60.90 43.62 14 33 4067.17 43.62 13 33 392 43.1 4.44 HVO_0401 UspA domain protein 43.42 1 5 5 19 7.936E8 15.98 32.89 4 8 1162.39 43.42 5 11 152 16.4 4.79 HVO_0467 PhoU/TrkA-C domain protein 43.03 1 14 14 48 3.915E8 39.71 43.03 14 24 2897.36 43.03 14 24 402 43.3 4.49 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 43.03 1 10 10 50 7.541E8 57.36 43.03 10 25 3377.06 43.03 10 25 330 36.3 4.35 HVO_0859 FeS assembly ATPase SufC 42.86 1 13 13 114 3.166E9 92.05 41.20 12 56 7044.51 42.86 13 58 301 33.4 4.35 HVO_1637 FKBP-type peptidylprolyl isomerase 42.81 1 8 9 49 4.830E9 40.56 34.31 8 24 2768.54 42.81 9 25 306 33.8 3.76 HVO_0980 NADH dehydrogenase-like complex subunit CD 42.73 1 15 21 107 2.040E9 73.29 42.73 21 54 5986.78 42.73 21 53 557 63.4 4.53 HVO_0104 DNA repair and recombination protein RadA 42.57 1 13 13 79 2.820E9 61.25 37.32 12 38 5644.80 42.57 13 41 343 37.3 4.64 HVO_1504 3-isopropylmalate dehydratase large subunit 42.49 1 16 16 90 2.174E9 105.03 42.49 16 45 6957.84 42.49 16 45 473 51.6 4.55 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.48 1 9 9 43 9.763E8 55.10 38.35 8 21 3367.69 42.48 9 22 266 27.8 4.84 HVO_0109 cysteine desulfurase 42.25 1 14 14 51 7.099E8 46.09 42.25 14 24 3435.74 42.25 14 27 426 46.8 4.56 HVO_0424 ABC-type transport system ATP-binding protein 42.22 1 18 18 71 6.488E8 66.39 42.22 18 35 3773.15 42.22 18 36 604 67.2 4.49 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 42.08 1 9 9 47 1.354E9 49.60 42.08 9 23 3045.35 42.08 9 24 259 28.0 4.50 HVO_2419 hydroxymethylglutaryl-CoA synthase 42.02 1 14 14 68 1.701E9 46.85 42.02 14 34 3168.76 42.02 14 34 445 50.1 4.64 HVO_0511 NAD-dependent epimerase/dehydratase 41.98 1 7 7 36 2.605E8 17.63 41.98 7 18 1520.31 41.98 7 18 262 29.3 4.78 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 41.94 1 12 12 56 1.300E9 56.62 41.94 12 28 3616.92 38.63 11 28 453 47.5 4.63 HVO_1973 conserved hypothetical protein 41.92 1 4 4 18 3.525E8 14.68 41.92 4 9 1187.85 41.92 4 9 167 18.1 4.36 HVO_A0156 acyl-CoA synthetase 41.72 1 8 20 101 2.569E9 93.72 39.16 18 49 6257.41 41.72 20 52 664 74.0 4.40 HVO_2981 uracil phosphoribosyltransferase 41.59 1 9 9 40 2.358E9 24.00 39.38 8 17 2650.95 41.59 9 23 226 24.5 4.49 HVO_0789 tryptophan synthase alpha subunit 41.52 1 7 7 48 5.647E8 43.49 41.52 7 25 2746.45 41.52 7 23 277 29.6 4.21 HVO_B0059 cobalt-precorrin 5A hydrolase 41.41 1 10 10 43 9.126E8 42.41 38.96 9 21 2831.05 41.41 10 22 326 34.5 4.51 HVO_0324 arginine--tRNA ligase 41.40 1 22 22 102 1.717E9 96.32 41.40 22 50 6204.91 41.40 22 52 587 65.0 4.35 HVO_0313 A-type ATP synthase subunit E 41.24 1 6 7 35 3.771E8 32.39 31.44 4 15 2372.25 41.24 7 20 194 22.0 4.31 HVO_0743 probable phosphodiesterase 41.20 1 21 21 131 2.393E9 105.38 41.20 21 65 7918.96 41.20 21 66 449 50.5 4.56 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 41.19 1 12 12 42 3.079E8 28.62 41.19 12 21 2176.04 41.19 12 21 454 48.5 4.46 HVO_1481 UspA domain protein 41.10 1 5 5 36 1.405E9 39.76 41.10 5 18 2373.55 41.10 5 18 163 17.7 4.40 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 40.93 1 11 11 61 2.091E9 51.21 37.07 9 26 4901.52 40.93 11 35 259 29.9 4.36 HVO_0894 acyl-CoA synthetase 40.63 1 8 19 113 2.569E9 116.45 39.12 18 55 7292.56 40.63 19 58 662 74.3 4.48 HVO_1623 conserved hypothetical protein 40.60 1 8 8 28 3.283E8 26.80 40.60 8 15 1679.45 31.21 7 13 298 32.8 4.56 HVO_1187 conserved hypothetical protein 40.56 1 5 5 14 9.183E7 6.18 40.56 5 7 632.58 40.56 5 7 143 16.4 4.86 HVO_0046 putative glutamate--argW ligase 40.55 1 9 9 47 8.043E8 39.47 40.55 9 23 2865.00 40.55 9 24 291 31.9 4.87 HVO_2552 30S ribosomal protein S4e 40.49 1 8 8 105 1.023E10 91.70 38.46 7 51 6192.10 40.49 8 54 247 26.6 4.58 HVO_2130 IclR family transcription regulator 40.44 1 10 10 28 4.824E8 31.15 40.44 10 15 2029.02 32.35 8 13 272 30.1 5.55 HVO_B0061 precorrin-2 C20-methyltransferase 40.43 1 7 7 33 5.540E8 21.19 32.77 6 16 1745.24 40.43 7 17 235 25.3 4.63 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 40.41 1 17 17 289 1.159E10 288.41 39.14 16 145 19504.97 40.41 17 144 631 68.4 4.49 HVO_1590 DnaK-type molecular chaperone Hsp70 40.32 1 21 21 137 4.872E9 124.82 39.52 20 69 8624.72 40.32 21 68 625 67.2 4.18 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 32 2.864E8 29.51 40.26 5 16 2154.09 40.26 5 16 154 17.5 4.50 HVO_0860 SufB domain protein 40.13 1 14 14 112 4.122E9 86.42 36.97 13 52 7519.12 40.13 14 60 476 53.2 4.69 HVO_A0205 CRISPR-associated endoribonuclease Cas6 40.07 1 10 10 50 1.281E9 50.51 40.07 10 25 3919.95 40.07 10 25 272 31.0 5.44 HVO_0549 2-keto-3-deoxygluconate kinase 40.00 1 11 12 33 7.296E8 18.24 36.25 11 15 1835.06 40.00 12 18 320 34.1 4.34 HVO_A0206 CRISPR-associated protein Cas8b 39.89 1 24 24 95 1.409E9 71.25 39.89 24 49 5076.15 35.01 21 46 717 79.3 4.60 HVO_2225 AstE family protein 39.88 1 7 7 26 9.178E8 21.20 39.88 7 13 1387.15 39.88 7 13 341 36.9 4.53 HVO_2205 arNOG06768 family NADH-binding domain protein 39.87 1 8 8 26 1.764E8 29.83 39.87 8 13 1688.47 39.87 8 13 301 32.0 5.00 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 39.78 1 16 16 67 6.822E8 69.96 39.78 16 34 4381.07 39.78 16 33 626 67.6 4.65 HVO_1854 histidine--tRNA ligase 39.68 1 15 15 66 1.163E9 61.01 39.68 15 32 4591.44 39.68 15 34 431 47.1 4.37 HVO_1545 dihydroxyacetone kinase subunit DhaL 39.66 1 7 7 54 1.351E9 44.33 39.66 7 27 3104.59 39.66 7 27 232 24.8 4.48 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 39.64 1 8 8 58 2.087E9 65.24 39.64 8 29 4382.31 39.64 8 29 280 30.1 4.44 HVO_1507 acetolactate synthase small subunit 39.45 1 6 6 25 3.393E8 20.85 39.45 6 12 1599.53 39.45 6 13 218 23.7 4.94 HVO_0358 homoserine dehydrogenase 39.43 1 7 7 34 1.266E9 30.46 39.43 7 17 1956.94 39.43 7 17 317 32.4 4.44 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 39.37 1 8 8 29 6.081E8 18.97 35.04 7 13 1749.90 39.37 8 16 254 26.9 4.42 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 39.34 1 10 10 22 1.042E9 16.90 39.34 10 12 1346.96 30.09 8 10 422 43.6 4.72 HVO_1198 UspA domain protein 39.31 1 5 5 16 5.866E8 13.68 39.31 5 8 955.75 39.31 5 8 145 15.6 4.75 HVO_1031 thioredoxin-disulfide reductase 39.18 1 9 9 44 7.452E8 38.64 39.18 9 22 2643.77 39.18 9 22 342 37.4 4.46 HVO_0809 methionine--tRNA ligase 38.65 1 19 19 77 1.059E9 73.71 38.65 19 38 5401.71 38.65 19 39 740 81.9 4.37 HVO_A0406 conserved hypothetical protein 38.52 1 2 10 27 5.955E8 18.84 33.58 9 13 1445.61 38.52 10 14 405 44.4 5.30 HVO_2726 glutamate--tRNA ligase 38.46 1 19 19 69 7.765E8 38.91 38.46 18 33 3363.76 38.46 19 36 585 65.2 4.58 HVO_2621 phosphoenolpyruvate carboxylase 38.13 1 26 26 116 1.457E9 90.55 38.13 26 59 6427.62 38.13 26 57 897 102.3 4.64 17318569 keratin 1 [Homo sapiens] 38.04 1 1 27 169 2.503E9 170.17 38.04 27 84 11430.43 38.04 27 85 644 66.0 8.12 HVO_1212 KaiC-type circadian regulator CirA 37.80 1 8 8 57 2.208E9 61.22 37.80 8 29 4271.60 37.80 8 28 246 27.5 4.45 HVO_2435 peptidase M24 family protein 37.77 1 8 8 29 4.407E8 22.16 37.77 8 15 1747.26 33.42 7 14 368 40.0 4.53 HVO_2188 phosphoribosylformylglycinamidine synthase 1 37.50 1 6 6 28 5.080E8 32.92 37.50 6 14 1758.67 37.50 6 14 224 23.9 4.36 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 37.50 1 17 18 88 2.029E9 91.80 37.50 17 45 5987.78 37.50 18 43 624 67.6 4.27 HVO_B0118 SMC-like protein Sph2 37.42 1 23 24 134 2.187E9 140.12 37.42 24 67 8429.70 37.42 24 67 644 73.8 4.41 HVO_0480 phosphoglycerate kinase 37.41 1 13 13 58 1.854E9 55.11 37.41 13 29 3756.62 37.41 13 29 401 43.6 4.37 HVO_2700 AAA-type ATPase (CDC48 subfamily) 37.40 1 24 25 109 6.696E8 78.61 37.40 25 55 5722.70 37.40 25 54 754 82.8 4.75 HVO_0167 adenosylhomocysteinase 37.38 1 11 11 46 9.755E8 49.78 33.18 10 21 3850.26 37.38 11 25 428 46.6 4.39 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.35 1 13 13 129 3.857E9 102.89 37.35 13 64 7099.08 37.35 13 65 332 34.8 4.22 HVO_B0114 IclR family transcription regulator 37.30 1 9 9 26 1.207E8 18.61 37.30 9 13 1470.77 37.30 9 13 252 28.4 5.44 HVO_0874 beta-lactamase domain protein 37.19 1 19 19 74 1.943E9 67.50 37.19 19 37 5506.79 37.19 19 37 640 71.9 5.14 HVO_1084 adenylosuccinate lyase 37.15 1 13 13 51 6.213E8 33.85 33.05 11 26 2829.41 37.15 13 25 463 50.8 4.70 HVO_1076 sugar nucleotidyltransferase 36.96 1 8 8 43 1.228E9 42.28 35.09 7 22 2732.83 36.96 8 21 322 35.8 4.20 47132620 keratin 2a [Homo sapiens] 36.93 1 15 20 82 2.058E9 84.98 36.93 20 40 6065.13 36.93 20 42 639 65.4 8.00 HVO_1091 proteasome alpha subunit 36.90 1 8 9 43 1.684E9 57.95 33.33 8 21 3379.32 36.90 9 22 252 27.6 4.56 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 36.84 1 5 5 31 1.767E9 25.42 36.84 5 16 2251.74 36.84 5 15 190 20.6 4.30 HVO_2454 anthranilate synthase component I 36.83 1 15 15 52 9.708E8 53.74 36.83 15 26 3401.23 36.83 15 26 524 55.9 4.56 HVO_0788 tryptophan synthase beta subunit 36.73 1 9 9 29 5.230E8 28.51 36.73 9 16 1819.29 25.83 7 13 422 45.7 4.65 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 36.65 1 0 26 165 2.503E9 165.75 36.65 26 82 11153.85 36.65 26 83 644 66.0 8.12 HVO_2961 dihydrolipoyl dehydrogenase 36.63 1 14 14 58 7.544E8 60.48 30.95 12 28 3974.29 36.63 14 30 475 49.9 4.41 HVO_0911 GTP-binding protein Drg 36.59 1 10 10 36 1.388E8 23.82 36.59 10 18 1624.34 36.59 10 18 369 40.5 4.81 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 36.59 1 31 31 172 1.894E9 152.00 35.04 29 83 10643.96 36.59 31 89 1033 114.3 4.45 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 36.43 1 8 8 59 9.012E8 55.75 33.87 7 28 4176.39 36.43 8 31 431 46.1 4.48 HVO_0661 dCTP deaminase (dUMP-forming) 36.41 1 6 6 25 2.939E8 23.90 36.41 6 13 1407.67 36.41 6 12 195 21.2 4.59 HVO_0717 "cell division protein FtsZ, type I" 36.41 1 12 12 72 4.972E9 80.76 36.41 12 36 5302.19 36.41 12 36 379 39.8 4.40 HVO_1284 GTP cyclohydrolase III 36.40 1 7 7 36 5.633E8 38.07 36.40 7 18 2840.51 36.40 7 18 261 28.9 4.70 HVO_1649 methionine adenosyltransferase 36.32 1 12 12 55 8.676E8 45.37 36.32 12 28 3439.34 36.32 12 27 402 43.5 4.45 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 36.31 1 13 13 70 9.075E8 50.44 36.31 13 33 4157.16 36.31 13 37 471 51.0 4.48 HVO_0806 pyruvate kinase 36.24 1 14 14 85 1.745E9 80.58 36.24 14 43 5335.85 36.24 14 42 585 62.0 4.54 HVO_1684 threonine--tRNA ligase 36.08 1 19 19 91 2.097E9 74.31 36.08 19 45 6061.75 36.08 19 46 643 73.4 4.45 HVO_0206 alanine--tRNA ligase 35.90 1 25 25 104 5.718E8 71.37 31.34 23 50 5463.31 35.90 25 54 922 102.4 4.54 HVO_1172 NAD-dependent epimerase/dehydratase 35.87 1 9 9 29 2.169E9 23.69 35.87 9 15 1760.67 35.87 9 14 315 34.9 4.34 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 35.84 1 8 8 50 1.018E9 41.89 35.84 8 25 3178.92 35.84 8 25 226 25.5 4.25 HVO_0388 homolog to ribonuclease R 35.76 1 14 14 55 3.215E8 54.66 35.76 14 29 3266.80 33.03 13 26 439 50.3 4.73 HVO_2624 CTP synthase 35.70 1 13 13 57 1.666E9 49.36 31.69 11 28 3611.23 31.15 12 29 549 60.8 4.70 HVO_0353 30S ribosomal protein S12 35.21 1 6 6 28 1.259E9 33.48 35.21 6 14 1967.16 35.21 6 14 142 15.5 9.91 HVO_0138 tyrosine--tRNA ligase 35.06 1 7 7 45 1.012E9 18.46 35.06 7 22 1918.75 35.06 7 23 328 36.1 4.34 HVO_2333 conserved hypothetical protein 34.74 1 9 9 25 2.139E8 9.82 34.74 9 13 1087.95 34.74 9 12 308 34.9 4.54 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 34.71 1 14 14 60 6.154E8 43.69 34.71 14 30 3231.67 31.89 13 30 461 50.7 4.73 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 34.51 1 14 14 60 1.101E9 66.91 34.51 14 30 3806.49 34.51 14 30 623 62.1 5.30 HVO_2721 amidophosphoribosyltransferase 34.48 1 10 10 40 1.061E9 38.26 34.48 10 19 2348.67 34.48 10 21 493 53.4 4.78 HVO_0729 inorganic pyrophosphatase 34.46 1 7 7 42 1.579E9 49.29 34.46 7 21 3018.57 34.46 7 21 177 20.4 4.16 HVO_1025 acetyl-CoA C-acyltransferase 34.46 1 8 8 36 8.389E8 37.03 34.46 8 18 2239.83 34.46 8 18 383 40.7 4.56 HVO_2813 RimK family protein 34.44 1 12 12 81 1.509E9 78.08 32.67 11 41 5589.48 34.44 12 40 453 49.0 4.73 HVO_2436 malic enzyme (NADP) 34.35 1 16 20 84 8.403E8 96.07 34.35 20 42 5881.06 34.35 20 42 751 81.4 4.55 HVO_1082 homolog to orotate phosphoribosyltransferase 34.29 1 6 6 20 5.188E8 12.61 34.29 6 11 1085.12 30.95 5 9 210 22.3 4.42 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 34.25 1 9 9 38 6.333E8 25.99 31.22 8 17 1832.35 34.25 9 21 362 39.6 4.82 HVO_1506 ketol-acid reductoisomerase 34.20 1 8 8 31 5.233E8 34.22 32.18 7 15 2117.72 34.20 8 16 348 37.9 4.34 HVO_0314 A-type ATP synthase subunit C 33.91 1 11 12 39 1.044E9 27.64 29.89 11 20 2300.04 31.32 11 19 348 38.7 4.50 HVO_0349 DNA-directed RNA polymerase subunit A' 33.81 1 26 26 108 1.128E9 104.14 33.81 26 53 7515.94 33.81 26 55 976 108.8 4.81 HVO_1690 DHH family phosphoesterase 33.81 1 10 10 46 4.346E8 48.83 33.81 10 23 3224.42 33.81 10 23 485 52.1 4.48 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 33.79 1 11 11 51 6.881E8 50.86 33.79 11 26 3579.75 30.22 10 25 364 39.3 4.35 HVO_1291 fumarylacetoacetase family protein 33.74 1 4 4 21 7.870E8 28.54 33.74 4 11 1289.38 33.74 4 10 243 26.3 4.55 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 33.61 1 9 9 36 2.893E8 31.34 27.27 7 17 2449.40 33.61 9 19 363 39.3 4.97 HVO_0417 metal-dependent carboxypeptidase 33.47 1 14 14 45 8.718E8 35.23 27.49 12 21 2762.00 33.47 14 24 502 57.3 4.42 HVO_1660 DisA-N domain protein 33.46 1 7 7 25 7.061E8 27.00 33.46 7 12 1835.24 33.46 7 13 269 28.9 4.73 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 33.33 1 11 11 48 8.310E8 50.63 33.33 11 24 3106.22 33.33 11 24 348 38.2 4.32 HVO_2912 ThiJ/PfpI domain protein 33.33 1 4 4 15 1.243E8 11.68 28.36 3 7 724.10 33.33 4 8 201 20.9 4.36 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 33.33 1 7 7 38 1.353E9 35.36 33.33 7 18 2624.76 33.33 7 20 252 26.0 4.39 40354192 keratin 10 [Homo sapiens] 33.22 1 0 20 84 1.504E9 74.91 33.22 20 42 5105.43 33.22 20 42 584 58.8 5.16 HVO_1459 ThuA family protein 33.19 1 4 4 19 6.595E8 21.63 33.19 4 9 1192.69 33.19 4 10 238 26.8 4.67 HVO_2336 pyridoxal biosynthesis lyase PdxS 33.11 1 8 8 32 2.151E8 23.71 29.47 6 15 1862.09 33.11 8 17 302 32.5 4.81 HVO_A0636 YbaK domain protein 32.91 1 3 3 10 6.361E7 10.11 32.91 3 5 526.49 32.91 3 5 158 16.7 4.54 HVO_0997 peptidase M24 family protein 32.88 1 7 7 20 1.425E8 12.52 32.88 7 9 925.65 32.88 7 11 368 39.9 4.49 HVO_0292 replication protein A 32.80 1 8 8 36 6.043E8 37.41 32.80 8 19 2463.13 32.80 8 17 311 34.6 4.31 HVO_2013 "FtsZ family protein, type III" 32.74 1 6 6 24 4.255E8 15.09 32.74 6 11 1590.87 32.74 6 13 394 41.5 4.61 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 32.72 1 0 20 84 1.504E9 74.91 32.72 20 42 5105.43 32.72 20 42 593 59.5 5.21 HVO_0087 porphobilinogen synthase 32.72 1 8 8 29 3.897E8 25.16 32.72 8 14 1543.82 32.72 8 15 327 35.3 4.72 HVO_2643 NADPH:quinone reductase 32.66 1 8 8 37 5.415E8 35.29 32.08 7 19 2352.79 32.66 8 18 346 37.2 4.55 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 32.66 1 8 8 48 2.106E9 42.59 27.95 7 23 2683.90 32.66 8 25 297 31.3 4.36 HVO_2913 superoxide dismutase (Mn) 32.66 1 0 4 25 4.233E9 24.51 32.66 4 13 1778.32 32.66 4 12 199 22.3 4.48 HVO_A0475 superoxide dismutase (Mn) 32.50 1 0 4 25 4.233E9 24.51 32.50 4 13 1778.32 32.50 4 12 200 22.4 4.45 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 32.41 1 6 6 24 5.364E8 15.14 19.37 4 11 1319.38 32.41 6 13 253 26.0 4.60 HVO_1572 DNA gyrase subunit B 32.39 1 16 16 58 6.513E8 42.27 28.01 15 30 3233.58 30.05 15 28 639 71.2 4.83 HVO_1901 translation initiation factor aIF-2 gamma subunit 32.36 1 10 10 58 2.420E9 36.69 25.79 9 29 3089.12 32.36 10 29 411 43.9 4.36 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 32.33 1 10 10 32 3.597E8 29.85 32.33 10 17 1663.49 30.00 9 15 430 45.1 4.50 HVO_A0458 ParA domain protein 32.30 1 7 7 20 2.236E8 15.32 32.30 7 10 979.47 32.30 7 10 291 32.2 4.79 HVO_1573 DNA gyrase subunit A 32.25 1 24 24 82 9.415E8 71.45 29.23 23 40 4853.53 31.21 23 42 862 94.8 4.56 HVO_2790 ATP-binding protein Mrp 32.08 1 7 7 30 4.596E8 24.95 32.08 7 15 1783.96 32.08 7 15 346 36.8 4.50 HVO_2952 tRNA-splicing endonuclease 31.86 1 7 7 20 1.472E8 8.87 31.86 7 10 768.48 31.86 7 10 339 37.4 4.74 HVO_0122 phosphoglycerate dehydrogenase 31.79 1 6 6 25 3.641E8 22.49 24.69 5 12 1474.02 31.79 6 13 324 35.3 5.35 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 31.77 1 10 10 42 6.999E8 32.95 31.77 10 21 2785.91 31.77 10 21 447 48.5 4.56 HVO_1133 conserved hypothetical protein 31.68 1 2 2 6 9.506E7 6.72 31.68 2 3 522.88 31.68 2 3 101 11.7 4.58 HVO_2861 conserved hypothetical protein 31.64 1 9 9 48 1.185E9 40.50 31.64 9 24 2946.72 31.64 9 24 275 29.1 4.27 HVO_A0277 "ribonuclease H, type 1 (nonfunctional)" 31.61 1 2 2 2 0.000E0 20.00 31.61 2 2 193 20.8 4.55 HVO_1932 2-D-hydroxyacid dehydrogenase 31.49 1 8 8 28 3.294E8 26.42 31.49 8 14 1810.53 31.49 8 14 308 33.0 4.60 HVO_1164 HD family hydrolase 31.48 1 7 7 28 4.433E8 15.11 31.48 7 14 1521.28 31.48 7 14 270 29.8 4.87 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 19 1.975E9 16.92 31.45 3 10 1261.52 31.45 3 9 124 14.2 5.22 HVO_1804 nicotinate phosphoribosyltransferase 31.44 1 9 9 20 3.419E8 16.12 24.23 7 9 1169.65 31.44 9 11 388 41.1 4.60 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 31.40 1 13 13 40 2.116E8 32.95 31.40 13 20 2514.79 31.40 13 20 516 56.7 4.89 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 31.25 1 6 6 20 3.454E8 17.39 31.25 6 10 1595.71 31.25 6 10 336 36.0 4.51 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 31.17 1 16 16 74 8.350E8 66.48 29.00 15 36 5475.47 31.17 16 38 600 65.3 4.68 HVO_1967 glucose-6-phosphate isomerase 31.16 1 10 10 35 3.553E8 25.42 31.16 10 17 2207.04 31.16 10 18 430 45.6 4.40 HVO_1575 arginase 31.10 1 7 7 16 1.974E8 9.21 31.10 7 8 804.50 31.10 7 8 299 31.0 4.58 HVO_0601 homoserine dehydrogenase 31.01 1 5 5 24 6.812E8 27.46 31.01 5 12 1729.53 31.01 5 12 316 32.2 4.25 HVO_0979 NADH dehydrogenase-like complex subunit B 30.90 1 7 7 26 3.016E8 23.89 30.90 7 13 1392.18 30.90 7 13 233 26.1 5.01 HVO_1541 glycerol kinase 30.59 1 13 13 82 2.966E9 54.77 27.25 12 40 4949.11 30.59 13 42 510 56.7 4.50 HVO_2781 DNA-directed RNA polymerase subunit D 30.50 1 6 6 39 2.791E9 25.13 26.25 5 19 2354.04 30.50 6 20 259 28.1 4.32 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 30.38 1 10 10 46 1.074E9 46.17 30.38 10 23 2622.45 30.38 10 23 474 53.4 4.59 HVO_1371 glutamate 5-kinase 30.23 1 7 7 23 4.310E8 24.35 27.24 6 11 1855.62 30.23 7 12 301 32.0 4.25 HVO_1880 conserved hypothetical protein 30.22 1 6 6 22 1.276E8 19.58 30.22 6 11 1547.65 30.22 6 11 225 23.8 4.59 HVO_1140 acyl-CoA dehydrogenase 30.00 1 9 9 37 4.915E8 26.02 30.00 9 18 2175.87 30.00 9 19 380 41.2 4.55 HVO_2773 30S ribosomal protein S2 30.00 1 5 5 41 2.949E9 38.17 30.00 5 20 2568.32 30.00 5 21 260 28.3 4.16 HVO_A0273 ThuA family protein 29.96 1 4 4 13 8.346E7 10.86 29.96 4 7 732.50 29.96 4 6 237 26.5 4.77 HVO_1577 conserved hypothetical protein 29.94 1 5 5 15 4.972E8 7.29 24.86 4 7 919.35 29.94 5 8 177 19.4 4.74 HVO_2156 UspA domain protein 29.90 1 6 6 19 7.929E8 16.66 21.26 5 9 1325.12 29.90 6 10 301 31.6 4.69 HVO_2756 50S ribosomal protein L10 29.89 1 8 8 49 8.861E8 30.26 29.89 8 24 2315.41 29.89 8 25 348 36.9 3.99 HVO_0415 repair helicase 29.87 1 15 15 64 8.807E8 56.51 29.87 15 31 4203.50 29.87 15 33 616 69.6 4.70 HVO_1858 30S ribosomal protein S19e 29.80 1 2 2 3 4.433E7 205.55 29.80 2 3 151 16.7 4.84 HVO_2040 NAD-dependent epimerase/dehydratase 29.74 1 4 8 55 1.570E9 41.07 29.74 8 28 3059.05 29.74 7 27 306 33.8 4.51 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 29.69 1 3 3 7 1.440E8 4.52 20.31 2 3 444.85 29.69 3 4 128 13.0 4.31 HVO_1387 enoyl-CoA hydratase 29.57 1 7 7 26 3.747E8 12.19 29.57 7 13 1236.49 29.57 7 13 257 27.5 4.51 7428712 "keratin 1, type II, cytoskeletal - human" 29.39 1 0 22 140 2.340E9 146.95 29.39 22 69 9527.70 29.39 22 71 643 65.5 6.35 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 29.39 1 7 7 45 7.173E8 46.22 17.87 6 22 2814.36 29.39 7 23 347 36.8 4.93 HVO_1306 chorismate synthase 29.35 1 10 10 53 4.565E8 56.13 29.35 10 27 2877.45 29.35 10 26 385 41.9 4.83 HVO_1894 conserved hypothetical protein 29.35 1 2 2 4 2.371E8 1.82 29.35 2 2 96.03 29.35 2 2 92 10.3 4.67 HVO_A0496 UspA domain protein 29.31 1 7 7 41 1.006E9 32.92 29.31 7 20 2565.62 29.31 7 21 290 31.4 4.60 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 29.26 1 6 6 24 4.269E8 24.26 29.26 6 12 1458.74 29.26 6 12 270 29.1 4.35 HVO_1018 RecJ domain protein 29.23 1 17 17 77 1.321E9 78.78 29.23 17 39 5191.21 27.96 16 38 633 69.8 4.58 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 29.20 1 9 9 51 2.691E9 48.89 29.20 9 26 3494.94 29.20 9 25 435 46.9 4.63 HVO_2708 YfiH family protein 29.19 1 7 7 22 8.176E8 23.61 29.19 7 11 1843.17 29.19 7 11 322 35.4 4.35 HVO_1125 cysteine--tRNA ligase 29.15 1 10 10 40 4.235E8 34.38 29.15 10 20 2537.19 29.15 10 20 494 55.2 4.56 HVO_2716 acyl-CoA dehydrogenase 29.13 1 8 8 28 4.107E8 34.04 23.10 6 13 2276.18 29.13 8 15 381 41.3 4.65 HVO_3014 origin-associated GTP-binding protein OapA 29.11 1 7 7 17 1.845E8 9.90 25.82 6 8 824.08 29.11 7 9 213 24.0 5.01 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 29.00 1 5 5 19 1.659E8 17.92 19.91 4 9 1132.64 29.00 5 10 231 25.0 4.25 HVO_1446 "fructose-1,6-bisphosphatase" 28.96 1 5 5 15 1.044E8 7.45 18.52 3 5 1107.95 28.96 5 10 297 31.6 4.45 HVO_2562 50S ribosomal protein L23 28.92 1 2 2 3 4.817E7 519.27 28.92 2 3 83 9.4 5.48 HVO_1914 acetyl-CoA C-acyltransferase 28.91 1 7 7 28 8.040E8 21.97 26.26 6 13 1757.99 28.91 7 15 377 39.9 4.41 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 28.90 1 11 11 51 1.058E9 37.56 28.71 10 25 2737.19 28.90 11 26 526 57.2 4.31 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 28.87 1 4 4 10 1.846E8 2.63 28.87 4 5 360.01 28.87 4 5 97 10.8 4.53 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 28.19 1 4 4 20 6.785E8 11.00 28.19 4 10 1164.92 28.19 4 10 188 20.5 4.60 HVO_1020 HEAT-PBS family protein 28.16 1 10 10 44 1.554E9 41.61 28.16 10 22 3235.93 28.16 10 22 419 45.5 3.95 HVO_1576 NAD-dependent epimerase/dehydratase 28.10 1 4 8 39 9.255E8 35.36 28.10 8 21 2079.26 25.49 6 18 306 33.9 4.51 HVO_0357 ACT domain protein 28.04 1 5 5 21 8.573E8 19.08 28.04 5 11 1094.79 28.04 5 10 189 20.2 4.59 HVO_1531 UDP-glucose 6-dehydrogenase 27.91 1 12 12 51 6.468E8 42.71 26.28 11 25 3378.22 27.91 12 26 430 45.9 4.50 HVO_A0432 conserved hypothetical protein 27.90 1 0 8 22 5.691E8 18.84 27.90 8 11 1354.46 27.90 8 11 405 44.5 5.24 HVO_2496 adenylate kinase 27.88 1 6 6 32 1.071E9 30.36 27.88 6 16 2138.60 27.88 6 16 208 23.1 4.25 HVO_B0018 ParA domain protein 27.87 1 4 4 16 2.086E8 15.01 27.87 4 8 1123.01 27.87 4 8 287 31.7 4.74 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 27.84 1 10 10 60 1.967E9 44.39 27.84 10 30 3586.51 27.84 10 30 370 41.9 4.48 HVO_2467 NADPH:quinone reductase 27.73 1 6 6 28 4.581E8 25.67 27.73 6 14 1608.72 27.73 6 14 321 33.0 4.51 HVO_0466 citrate (si)-synthase 27.70 1 9 9 74 2.987E9 71.47 27.70 9 37 4692.98 27.70 9 37 379 41.8 4.55 HVO_2481 HD family hydrolase 27.69 1 5 7 16 1.512E8 7.02 27.69 7 8 708.14 27.69 7 8 390 42.7 6.14 HVO_2759 peptidase M42 family protein 27.68 1 7 7 30 2.533E8 38.39 27.68 7 15 2060.21 27.68 7 15 354 37.0 4.40 HVO_A0307 Lrp/AsnC family transcription regulator 27.68 1 4 4 10 1.607E8 9.58 27.68 4 5 668.61 27.68 4 5 177 19.4 4.39 HVO_2706 translation initiation factor aIF-2B delta subunit 27.66 1 5 5 17 5.748E8 11.56 17.02 4 8 1018.68 27.66 5 9 282 30.7 4.42 HVO_0049 argininosuccinate synthase 27.65 1 10 10 36 2.463E9 32.07 27.16 9 18 2189.25 25.68 9 18 405 44.5 4.34 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 27.62 1 8 8 25 2.379E8 18.46 24.42 7 11 1553.21 27.62 8 14 344 39.1 4.73 HVO_2779 50S ribosomal protein L18e 27.59 1 3 3 14 6.288E7 11.99 27.59 3 7 838.93 27.59 3 7 116 12.7 8.50 HVO_1824 conserved hypothetical protein 27.51 1 8 8 27 4.426E8 18.50 21.68 7 13 1450.24 27.51 8 14 429 47.4 4.20 HVO_2239 UspA domain protein 27.46 1 4 4 14 5.647E8 7.49 27.46 4 7 573.46 27.46 4 7 142 15.4 4.16 HVO_1866 uridylate kinase 27.43 1 6 6 22 9.771E8 18.28 27.43 6 11 1515.85 27.43 6 11 237 24.6 4.42 HVO_0243 threonine aldolase 27.27 1 8 8 27 3.972E8 24.46 27.27 8 14 1620.40 27.27 8 13 341 35.6 4.55 HVO_1370 gamma-glutamyl phosphate reductase 27.25 1 11 11 53 7.723E8 34.57 27.25 11 26 2742.61 27.25 11 27 444 48.1 4.34 HVO_0393 UvrABC system protein A 27.16 1 24 24 79 4.765E8 54.91 24.42 22 39 3902.08 27.16 24 40 983 108.6 4.82 HVO_1527 glucose-1-phosphate uridylyltransferase 27.16 1 8 8 39 5.470E8 25.81 27.16 8 19 2134.12 26.75 7 20 243 27.5 4.70 HVO_1778 catalase-peroxidase 27.16 1 12 12 55 1.183E9 69.88 27.16 12 28 4396.68 27.16 12 27 718 80.0 4.31 HVO_0573 endonuclease IV 27.15 1 5 5 18 9.112E8 5.69 27.15 5 9 731.49 27.15 5 9 291 31.4 4.44 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 27.08 1 8 8 27 1.074E9 23.37 18.23 6 12 1712.51 27.08 8 15 373 40.2 4.44 HVO_1593 PAC2 family protein 27.02 1 3 3 11 3.575E8 2.72 27.02 3 6 400.77 27.02 3 5 248 26.6 4.46 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 27.00 1 7 7 18 2.688E8 14.37 23.74 6 8 1067.95 27.00 7 10 337 35.9 4.69 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 26.97 1 4 5 19 4.243E8 14.97 26.97 5 9 1201.99 26.97 5 10 267 29.1 4.63 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 26.92 1 8 8 21 2.400E8 14.31 24.66 7 11 987.73 23.98 7 10 442 46.9 4.58 HVO_2313 siroheme decarboxylase AhbB 26.91 1 6 6 16 3.023E8 12.42 26.91 6 8 926.56 26.91 6 8 353 39.6 4.64 HVO_1579 uridine phosphorylase 26.84 1 4 4 11 1.884E8 6.97 15.07 3 5 605.85 26.84 4 6 272 29.0 4.64 HVO_1571 DNA topoisomerase VI subunit B 26.82 1 15 15 50 5.841E8 44.16 24.44 14 24 2737.94 26.82 15 26 798 87.4 4.73 HVO_0829 peptidase S9 family protein 26.81 1 11 11 41 5.149E8 25.74 22.04 9 19 2227.29 26.81 11 22 608 67.4 4.54 HVO_1478 transcription initiation factor TFB 26.81 1 5 8 46 8.341E8 34.26 26.81 8 23 2762.41 26.81 8 23 317 35.7 5.47 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 26.75 1 7 7 32 1.231E9 20.54 26.75 7 14 1762.68 26.75 7 18 415 44.4 4.41 HVO_1503 3-isopropylmalate dehydratase small subunit 26.73 1 4 4 10 2.471E8 9.35 10.89 2 4 687.43 26.73 4 6 202 22.0 4.15 HVO_2883 conserved hypothetical protein 26.50 1 14 14 42 2.570E8 28.95 25.36 13 21 2120.56 25.36 13 21 702 78.9 4.48 HVO_0354 30S ribosomal protein S7 26.47 1 5 5 18 4.086E8 12.26 26.47 5 9 923.73 26.47 5 9 204 22.6 5.14 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 26.43 1 7 7 26 3.557E8 32.98 26.43 7 13 2039.82 26.43 7 13 333 36.7 4.56 HVO_2425 GNAT family acetyltransferase 26.39 1 4 4 14 1.583E8 15.88 26.39 4 7 1116.24 26.39 4 7 216 24.4 4.54 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 26.34 1 11 11 45 6.856E8 39.56 26.34 11 24 2493.65 21.95 9 21 615 67.6 4.88 HVO_1553 hydroxypyruvate reductase 26.24 1 9 9 24 1.315E8 16.36 26.24 9 12 1250.01 26.24 9 12 442 45.2 4.50 HVO_1654 cysteine synthase 26.14 1 6 6 27 5.786E8 20.07 26.14 6 14 1507.93 26.14 6 13 306 32.3 4.32 HVO_2580 L-aspartate oxidase 25.88 1 10 10 35 1.770E8 31.41 25.88 10 17 1911.20 25.88 10 18 537 55.8 4.63 HVO_0812 phosphoenolpyruvate synthase 25.76 1 16 16 62 4.496E8 65.01 25.76 16 32 4058.14 25.76 16 30 761 83.1 4.63 HVO_2266 hypothetical protein 25.76 1 9 9 32 2.995E8 15.48 25.76 9 16 1734.21 25.76 9 16 493 56.7 4.54 HVO_1488 D-gluconate dehydratase 25.73 1 7 9 52 1.284E9 40.91 25.73 9 26 3367.56 25.73 9 26 412 45.8 4.60 HVO_A0485 aminotransferase class V 25.64 1 7 7 23 3.715E8 16.11 21.94 6 11 1114.71 25.64 7 12 351 37.3 4.26 HVO_0484 50S ribosomal protein L10e 25.57 1 4 5 18 1.311E8 3.97 25.57 5 9 715.49 25.57 5 9 176 19.8 8.72 HVO_0552 DNA mismatch repair protein MutS 25.43 1 17 17 55 3.620E8 41.40 25.43 17 28 3143.66 23.38 16 27 924 99.2 4.65 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 25.43 1 11 11 33 3.281E8 27.45 25.43 11 16 1887.39 25.43 11 17 586 63.4 4.70 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 25.39 1 10 10 31 3.558E8 28.05 22.85 9 15 1845.27 25.39 10 16 512 53.8 4.78 HVO_0694 probable phosphoribosyltransferase 25.32 1 5 5 21 3.234E8 17.13 25.32 5 10 1307.05 25.32 5 11 237 27.0 4.32 HVO_A0153 UspA domain protein 25.31 1 3 3 12 6.782E7 11.01 25.31 3 6 524.47 25.31 3 6 162 17.4 4.97 HVO_1727 TATA-binding transcription initiation factor 25.27 1 5 5 31 2.139E9 24.80 25.27 5 16 2109.22 25.27 5 15 186 19.9 4.36 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 25.25 1 4 4 24 2.481E8 17.55 25.25 4 12 1340.44 25.25 4 12 202 22.2 5.11 >sp|TRYP_PIG| 25.11 1 4 4 92 4.570E10 99.23 25.11 4 44 7310.76 25.11 4 48 231 24.4 7.18 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 25.11 1 15 15 59 1.186E9 50.81 25.11 15 29 3678.64 25.11 15 30 697 74.5 4.13 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 25.08 1 6 6 22 1.671E8 16.23 25.08 6 11 1090.46 25.08 6 11 327 36.2 4.63 HVO_1327 AAA-type ATPase (CDC48 subfamily) 25.00 1 12 13 44 3.649E8 26.07 23.23 12 21 2083.97 25.00 13 23 736 78.1 4.88 HVO_0916 diphthine synthase 24.91 1 5 5 16 4.667E8 17.91 24.91 5 8 996.89 24.91 5 8 269 29.1 4.54 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 24.87 1 4 4 20 2.199E8 9.90 17.99 3 9 1177.01 24.87 4 11 189 21.7 4.46 HVO_1332 conserved hypothetical protein 24.81 1 3 3 9 3.310E8 7.88 16.28 2 4 804.53 24.81 3 5 129 14.9 4.16 HVO_1348 probable YjeF family carbohydrate kinase 24.69 1 8 8 26 1.307E8 28.51 24.69 8 13 1481.35 24.69 8 13 478 48.8 4.45 HVO_0937 FMN-binding domain protein 24.66 1 2 2 6 1.327E8 3.89 24.66 2 3 164.26 24.66 2 3 146 16.2 4.36 HVO_1496 phosphotransferase system component I 24.60 1 12 12 51 6.952E8 50.68 24.60 12 25 3103.85 24.60 12 26 565 60.3 4.21 HVO_2707 GFO family oxidoreductase 24.46 1 8 8 34 9.936E8 41.20 22.58 7 17 2315.41 22.85 7 17 372 41.0 4.55 HVO_1965 rRNA maturation endonuclease Nob1 24.34 1 3 3 5 3.705E7 2.70 17.76 2 2 185.19 17.76 2 3 152 16.8 4.70 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 24.16 1 8 8 19 2.523E8 12.87 20.49 7 9 1143.23 24.16 8 10 327 36.0 4.73 HVO_1871 UPF0447 family protein 23.95 1 11 11 49 6.380E8 36.10 20.56 10 24 2823.51 23.95 11 25 501 56.1 4.59 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 23.84 1 6 6 14 1.487E8 4.57 23.84 6 6 564.59 23.84 6 8 323 34.9 5.24 HVO_1380 methylmalonyl-CoA mutase subunit A 23.84 1 9 9 29 2.239E8 16.95 20.07 8 14 1123.62 23.84 9 15 558 61.9 4.41 HVO_C0069 GFO family oxidoreductase 23.77 1 7 7 31 2.692E8 34.35 23.77 7 16 1789.36 23.77 7 15 324 36.0 5.10 HVO_1550 acyl-CoA thioester hydrolase 23.75 1 3 3 9 2.051E8 9.09 16.88 2 4 607.84 23.75 3 5 160 17.6 4.55 HVO_0304 electron transfer flavoprotein alpha subunit 23.66 1 4 4 10 2.540E8 8.13 20.50 3 5 548.87 23.66 4 5 317 33.5 4.18 HVO_1501 DeoR family transcription regulator GlpR 23.53 1 5 5 17 1.202E8 11.81 23.53 5 8 740.71 23.53 5 9 255 28.0 4.97 HVO_1918 probable metallo-beta-lactamase family hydrolase 23.51 1 3 3 7 8.412E7 0.00 23.51 3 3 251.64 23.51 3 4 302 34.0 4.55 HVO_2688 TrmB family transcription regulator 23.51 1 7 8 30 1.362E9 29.70 22.10 7 14 2184.26 23.51 8 16 353 39.3 4.58 HVO_0321 peptide chain release factor aRF-1 23.43 1 10 10 42 3.773E8 21.00 23.43 10 21 2134.64 23.43 10 21 414 46.6 4.83 HVO_B0371 aldehyde dehydrogenase 23.39 1 5 5 22 2.110E8 23.80 23.39 5 11 1230.30 23.39 5 11 496 52.5 4.39 HVO_1295 histidinol-phosphate aminotransferase 23.27 1 6 6 29 2.646E8 21.83 23.27 6 15 1519.46 23.27 6 14 361 39.4 4.51 HVO_2908 dihydropteroate synthase 23.22 1 6 6 21 2.449E8 19.11 23.22 6 11 1067.93 23.22 6 10 379 40.8 4.53 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 23.15 1 6 6 28 2.065E8 18.62 23.15 6 14 1488.21 18.52 5 14 324 36.6 4.68 HVO_2675 histidinol dehydrogenase 23.13 1 7 7 30 4.836E8 30.83 23.13 7 15 2358.81 23.13 7 15 428 45.4 4.50 HVO_2417 conserved hypothetical protein 23.08 1 3 3 10 2.230E8 8.07 23.08 3 5 477.85 23.08 3 5 195 21.6 3.65 HVO_2348 GTP cyclohydrolase MptA 23.05 1 5 5 45 3.953E8 25.22 23.05 5 23 1893.37 23.05 5 22 308 33.5 4.68 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 23.02 1 5 5 14 2.137E8 14.21 23.02 5 7 919.58 23.02 5 7 265 29.3 4.92 HVO_0209 acyl-CoA dehydrogenase 23.00 1 7 7 23 9.888E7 15.91 23.00 7 12 1050.83 19.12 6 11 387 42.4 4.93 HVO_0519 replication protein A 22.98 1 9 9 34 5.338E8 29.49 22.98 9 17 2208.56 20.50 8 17 483 51.0 4.13 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 22.97 1 6 6 28 5.999E8 14.49 22.97 6 15 1321.77 20.73 5 13 357 39.8 4.41 HVO_B0143 receiver/sensor box histidine kinase 22.95 1 11 11 38 3.015E8 28.06 22.95 11 19 2142.86 22.95 11 19 597 66.0 4.41 HVO_1123 thioredoxin-disulfide reductase 22.92 1 8 8 41 1.248E9 29.53 19.77 7 18 2586.78 22.92 8 23 349 37.3 4.32 HVO_1783 conserved hypothetical protein 22.77 1 3 3 8 7.025E7 7.32 22.77 3 4 456.01 22.77 3 4 224 24.1 5.90 HVO_2784 30S ribosomal protein S13 22.75 1 3 3 10 2.568E8 7.26 22.75 3 5 611.97 22.75 3 5 167 18.9 5.17 HVO_A0266 IclR family transcription regulator 22.75 1 5 5 22 1.429E8 18.33 22.75 5 11 1298.25 22.75 5 11 255 27.7 6.05 HVO_1867 lysine--tRNA ligase 22.70 1 11 11 36 3.921E8 26.24 22.70 11 18 1897.50 21.08 10 18 555 62.1 4.46 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 22.69 1 8 8 57 4.101E9 68.42 22.69 8 28 3723.27 22.69 8 29 357 40.3 4.40 HVO_1570 DNA topoisomerase VI subunit A 22.68 1 5 5 17 2.790E8 9.83 22.68 5 8 943.60 22.68 5 9 366 41.8 4.63 HVO_0469 AstE family protein 22.64 1 5 5 15 2.550E8 16.30 16.98 4 7 1002.58 22.64 5 8 318 33.9 5.85 HVO_2211 TrkA domain protein 22.47 1 5 5 13 1.544E8 10.52 22.47 5 7 594.85 22.47 5 6 227 24.5 4.72 HVO_2947 phenylalanine--tRNA ligase beta subunit 22.46 1 10 10 47 7.998E8 42.62 20.35 8 22 3128.16 22.46 10 25 570 63.3 4.46 HVO_0406 RNA-binding protein AU-1 22.44 1 7 7 20 2.308E8 15.13 22.44 7 10 1029.44 22.44 7 10 468 49.9 4.53 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 22.30 1 4 4 12 1.626E8 7.67 22.30 4 6 679.84 22.30 4 6 305 32.7 4.56 HVO_1465 naphthoate synthase 22.30 1 6 6 16 2.876E8 8.32 20.00 5 7 738.19 22.30 6 9 305 33.9 4.83 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 22.22 1 4 4 14 3.572E8 15.71 22.22 4 7 1111.28 22.22 4 7 324 33.6 3.99 HVO_1657 phosphoribosylamine--glycine ligase 22.20 1 8 8 41 1.866E9 33.52 19.39 7 19 2457.99 22.20 8 22 428 45.5 4.20 HVO_0195 ribose-5-phosphate isomerase 22.17 1 5 5 18 3.643E8 9.65 22.17 5 9 1029.59 22.17 5 9 230 23.2 4.54 HVO_1177 CinA N-terminal domain protein 22.17 1 3 3 6 8.892E7 2.32 22.17 3 3 180.44 22.17 3 3 230 24.5 4.36 HVO_1340 "probable glycosyltransferase, type 1" 22.13 1 7 7 28 3.479E8 10.29 22.13 7 14 1304.41 19.20 6 14 375 41.0 4.42 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 21.83 1 5 6 16 3.686E8 19.13 17.11 5 8 953.38 18.29 5 8 339 38.1 4.50 HVO_2581 quinolinate synthase A 21.56 1 7 7 25 3.713E8 18.40 21.56 7 12 1175.72 21.56 7 13 385 42.0 4.41 HVO_A0003 ParA domain protein 21.53 1 4 4 10 1.322E8 6.22 21.53 4 5 452.44 21.53 4 5 274 30.3 4.53 HVO_0639 AAA-type ATPase (MoxR subfamily) 21.52 1 6 6 19 1.196E8 13.04 18.99 5 8 1085.94 21.52 6 11 316 34.7 4.89 HVO_B0057 precorrin-3B C17-methyltransferase 21.51 1 4 4 15 7.890E8 15.74 21.51 4 8 938.72 21.51 4 7 344 36.3 4.31 HVO_0431 HAD superfamily hydrolase 21.48 1 5 5 14 9.492E7 12.36 21.48 5 7 798.49 21.48 5 7 284 30.4 4.26 HVO_2383 DNA repair and recombination protein RadB 21.40 1 3 3 10 9.861E7 12.91 21.40 3 5 691.86 21.40 3 5 229 24.6 5.02 HVO_2879 ornithine cyclodeaminase 21.39 1 5 5 23 4.851E8 8.69 13.86 4 10 1334.93 21.39 5 13 332 34.6 4.45 HVO_0054 glycine--tRNA ligase 21.38 1 8 8 34 2.187E9 37.12 19.02 7 16 2775.78 21.38 8 18 594 64.9 4.21 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 21.35 1 7 7 25 3.976E8 20.30 21.35 7 12 1523.32 16.91 6 13 473 50.8 4.58 HVO_2227 siroheme decarboxylase AhbA 21.33 1 5 5 14 1.222E8 10.52 21.33 5 7 688.67 21.33 5 7 347 39.1 4.69 HVO_0879 DUF371 family protein 21.28 1 2 2 4 3.643E7 3.31 21.28 2 2 285.24 21.28 2 2 141 15.3 4.65 HVO_0970 ribulose-bisphosphate carboxylase large subunit 21.26 1 7 7 41 4.535E8 36.98 19.32 6 20 2989.51 21.26 7 21 414 43.9 4.59 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 21.19 1 2 11 33 8.706E8 26.20 19.92 10 16 1942.91 21.19 11 17 472 51.6 5.16 HVO_1547 isoleucine--tRNA ligase 21.19 1 14 14 60 5.972E8 48.46 21.19 14 31 3330.78 19.65 13 29 1043 117.9 4.30 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 21.14 1 4 11 33 8.706E8 23.75 19.87 10 16 2031.18 21.14 11 17 473 51.2 5.05 HVO_1957 proteasome-activating nucleotidase 21.12 1 7 8 30 2.530E8 17.74 21.12 8 15 1717.88 21.12 8 15 412 45.6 4.48 HVO_1268 conserved hypothetical protein 21.10 1 3 3 10 9.474E7 11.91 21.10 3 5 894.75 21.10 3 5 237 26.4 5.21 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 21.10 1 12 12 50 4.941E8 45.25 18.70 11 24 3078.01 21.10 12 26 706 73.3 4.39 HVO_0350 DNA-directed RNA polymerase subunit A'' 21.00 1 9 9 36 2.405E9 38.41 21.00 9 19 2616.36 18.38 8 17 419 46.1 4.35 HVO_1079 sulfate adenylyltransferase small subunit 20.92 1 6 6 26 6.053E8 30.51 20.92 6 13 1939.25 20.92 6 13 325 37.5 4.18 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 20.88 1 2 2 10 9.707E7 7.41 20.88 2 5 610.26 20.88 2 5 91 10.4 4.07 HVO_0233 ribose-phosphate pyrophosphokinase 20.85 1 4 4 18 2.018E8 16.60 20.85 4 9 1101.20 20.85 4 9 283 29.6 4.40 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 20.82 1 10 10 24 2.228E8 12.30 20.82 10 14 1139.29 10.79 6 10 658 72.1 4.70 HVO_2797 uridine kinase 20.78 1 3 3 3 1.754E7 0.00 20.78 3 3 231 26.3 4.63 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 20.75 1 4 4 15 2.477E8 16.82 20.75 4 8 904.22 20.75 4 7 294 32.5 4.75 HVO_2347 conserved hypothetical protein 20.71 1 2 2 10 1.365E8 12.48 20.71 2 5 756.75 20.71 2 5 140 15.5 4.37 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 8 3.594E7 11.48 20.71 2 4 663.95 20.71 2 4 140 16.0 5.57 HVO_1412 diphosphomevalonate decarboxylase 20.68 1 6 6 30 2.221E9 18.11 20.68 6 15 1701.81 20.68 6 15 324 35.4 4.78 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 20.61 1 6 6 21 3.699E8 18.41 18.27 5 10 1325.90 20.61 6 11 427 45.4 4.56 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 20.60 1 5 6 17 2.217E8 19.99 20.60 6 9 1144.76 17.60 5 8 267 28.8 4.55 HVO_0745 "FtsZ family protein, type III" 20.56 1 5 5 9 8.453E7 6.73 12.22 4 4 557.16 20.56 5 5 360 37.1 4.51 HVO_0893 methylmalonyl-CoA mutase subunit A 20.49 1 8 8 24 4.899E8 24.14 20.49 8 12 1342.93 20.49 8 12 566 63.1 4.36 HVO_0876 methylglyoxal synthase 20.47 1 2 2 4 5.067E7 4.02 20.47 2 2 206.42 20.47 2 2 127 13.9 4.48 HVO_2951 tryptophan--tRNA ligase 20.42 1 7 7 20 2.174E8 17.20 20.42 7 10 893.89 20.42 7 10 529 59.1 4.53 HVO_2564 50S ribosomal protein L3 20.41 1 5 5 14 1.456E8 12.99 20.41 5 7 1123.55 20.41 5 7 338 37.2 6.68 HVO_1453 glutamate dehydrogenase (NADP) 20.38 1 7 7 23 5.627E8 12.88 18.47 6 11 1260.49 20.38 7 12 417 45.7 4.49 HVO_1698 CBS/parB domain protein 20.38 1 3 4 12 7.820E7 0.00 20.38 4 6 341.51 20.38 4 6 265 29.4 4.92 HVO_1847 oligoendopeptidase PepF 20.37 1 9 9 35 2.133E8 32.43 17.86 8 17 2198.17 20.37 9 18 599 68.5 4.41 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 20.25 1 4 4 9 1.121E8 2.58 20.25 4 5 260.03 16.88 3 4 237 25.4 4.46 HVO_B0382 TATA-binding transcription initiation factor 20.21 1 3 3 12 2.657E8 12.20 20.21 3 6 899.44 20.21 3 6 188 20.1 4.12 HVO_2555 30S ribosomal protein S17 20.18 1 2 2 3 9.290E7 1.91 20.18 2 3 114 12.7 4.81 HVO_1356 sensor box histidine kinase 20.00 1 8 8 22 2.154E8 16.54 18.18 7 11 999.71 20.00 8 11 550 61.1 4.60 HVO_1510 2-isopropylmalate synthase 20.00 1 5 5 18 1.125E9 18.33 18.18 4 9 1526.84 11.82 4 9 440 47.7 4.82 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 19.96 1 16 16 63 6.261E8 69.53 18.48 15 31 5166.38 19.96 16 32 1082 117.2 4.32 HVO_0787 indole-3-glycerol-phosphate synthase 19.92 1 4 4 12 1.519E8 8.97 19.92 4 6 555.50 19.92 4 6 251 26.7 4.44 HVO_1491 HAD superfamily hydrolase 19.85 1 7 7 20 1.735E8 13.40 18.38 6 10 1179.06 18.38 6 10 408 44.4 4.60 HVO_C0001 Orc1-type DNA replication protein 19.85 1 8 8 26 1.889E8 15.11 19.85 8 13 1320.75 19.85 8 13 408 45.2 4.97 HVO_1344 SBDS family protein 19.75 1 4 4 14 8.215E7 9.71 19.75 4 7 619.60 19.75 4 7 238 26.5 4.51 HVO_0214 L-lactate dehydrogenase 19.69 1 6 6 40 2.223E9 48.99 19.69 6 19 3123.13 19.69 6 21 320 34.5 4.49 HVO_0048 argininosuccinate lyase 19.67 1 6 6 26 2.472E8 26.78 19.67 6 13 1792.22 19.67 6 13 488 50.8 4.53 HVO_2690 GFO family oxidoreductase 19.67 1 7 7 36 9.808E8 27.75 19.67 7 18 2251.46 19.67 7 18 366 40.0 4.60 HVO_2456 anthranilate phosphoribosyltransferase 19.64 1 3 4 11 2.285E8 3.34 19.64 4 6 249.60 15.71 3 5 331 33.8 4.35 HVO_1878 NAD synthase 19.57 1 5 5 18 2.273E8 14.27 19.57 5 9 1030.22 19.57 5 9 276 29.6 4.37 HVO_2547 50S ribosomal protein L32e 19.57 1 3 3 11 1.720E8 12.11 12.34 2 5 762.63 19.57 3 6 235 25.8 4.75 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 19.57 1 2 2 4 2.283E8 301.45 19.57 2 4 184 20.0 4.75 HVO_A0133 conserved hypothetical protein 19.52 1 4 4 13 2.431E8 15.94 19.52 4 7 875.18 19.52 4 6 292 30.8 5.17 HVO_1354 DNA mismatch repair protein MutS 19.48 1 10 10 24 2.191E8 12.18 19.48 10 12 873.08 19.48 10 12 580 62.1 4.56 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 19.46 1 5 5 13 7.614E7 6.61 14.29 4 6 821.10 19.46 5 7 406 43.1 4.60 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 19.45 1 5 5 14 3.384E8 5.45 19.45 5 7 711.76 19.45 5 7 365 39.0 4.61 HVO_1885 TrkA domain protein 19.35 1 2 2 8 7.705E7 2.19 19.35 2 4 212.39 19.35 2 4 217 23.4 4.75 HVO_A0551 acyl-CoA synthetase 19.33 1 8 8 24 5.354E8 23.52 19.33 8 13 1400.46 16.17 6 11 538 59.6 4.65 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 22 1.737E9 18.70 19.31 5 11 1615.32 19.31 5 11 378 39.7 4.67 HVO_0180 23S rRNA (uridine-2'-O-) methyltransferase 19.31 1 4 4 14 1.400E8 5.90 19.31 4 7 430.13 19.31 4 7 259 28.3 4.70 HVO_2256 DUF262 family protein 19.26 1 9 9 29 3.166E8 19.82 19.26 9 15 1603.72 17.10 8 14 462 54.9 4.89 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 19.08 1 22 22 88 5.558E8 62.96 18.46 21 42 4969.41 18.54 21 46 1284 141.2 4.35 HVO_0670 glutathione S-transferase 19.02 1 6 6 14 1.229E8 6.14 11.35 4 6 662.18 17.79 5 8 326 38.1 4.56 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 19.02 1 4 4 18 1.415E8 14.06 19.02 4 9 1003.29 19.02 4 9 305 34.1 4.91 HVO_2536 CHP00300 family protein 18.99 1 4 4 14 2.763E8 6.99 18.99 4 7 518.93 18.99 4 7 416 44.8 4.51 HVO_1485 conserved hypothetical protein 18.96 1 2 2 4 5.350E7 0.00 18.96 2 2 81.49 18.96 2 2 211 23.0 4.42 HVO_1289 OsmC domain protein 18.94 1 2 2 10 2.800E9 4.90 18.94 2 5 420.95 18.94 2 5 132 14.2 3.85 HVO_0034 acyl-CoA thioester hydrolase 18.90 1 3 3 11 8.591E7 0.00 18.90 3 6 337.51 18.90 3 5 164 18.3 4.65 HVO_1816 dihydroorotase 18.88 1 5 5 30 2.567E8 15.36 18.88 5 15 1625.01 18.88 5 15 429 45.4 4.40 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 18.87 1 4 4 8 2.268E8 7.80 18.87 4 4 508.85 18.87 4 4 265 28.7 4.87 HVO_0697 PAC2 family protein 18.82 1 2 2 14 4.237E8 15.96 18.82 2 7 981.94 18.82 2 7 255 27.4 4.08 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 18.74 1 8 8 26 1.195E8 20.87 18.74 8 13 1541.78 18.74 8 13 459 50.5 4.63 HVO_1407 HTH domain protein 18.67 1 3 3 8 4.574E7 5.02 18.67 3 4 377.86 18.67 3 4 225 24.9 4.45 HVO_2717 alanine--tRNA ligase 18.59 1 6 6 20 1.268E8 22.99 15.58 5 9 1621.36 18.59 6 11 398 41.6 4.39 HVO_2662 homolog to lactoylglutathione lyase 18.54 1 5 5 15 8.240E8 12.83 15.50 4 7 813.98 18.54 5 8 329 36.5 4.48 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 18.47 1 4 4 14 1.487E8 16.41 18.47 4 7 951.30 18.47 4 7 287 31.8 4.93 HVO_0681 DNA topoisomerase I 18.45 1 13 13 36 2.608E8 28.18 18.45 13 19 1978.48 18.45 13 17 840 93.6 4.58 HVO_1508 acetolactate synthase large subunit 18.40 1 7 7 34 2.982E8 36.42 18.40 7 17 2234.27 18.40 7 17 587 62.3 4.36 HVO_0658 tRNA pseudouridine(13) synthase TruD 18.36 1 5 5 16 1.088E8 12.81 18.36 5 8 579.01 18.36 5 8 463 50.6 4.70 HVO_1134 conserved hypothetical protein 18.36 1 10 10 36 3.229E8 28.35 18.36 10 18 2076.91 18.36 10 18 757 80.6 4.35 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 17 3.783E8 11.81 18.29 4 9 1020.10 12.45 3 8 257 26.8 4.01 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 18.21 1 6 6 19 9.871E7 9.25 14.25 5 9 924.65 18.21 6 10 379 41.7 4.83 HVO_A0288 probable oxidoreductase (short-chain dehydrogenase family) 18.21 1 4 4 12 5.346E7 12.19 18.21 4 6 590.90 18.21 4 6 280 29.9 4.74 HVO_1287 PfpI family protease 18.18 1 2 2 6 1.458E8 4.60 18.18 2 3 190.14 18.18 2 3 198 21.5 4.53 HVO_A0150 TrmB family transcription regulator 18.08 1 7 7 16 2.349E8 4.20 18.08 7 9 462.67 16.10 6 7 354 39.0 4.63 HVO_0041 ornithine carbamoyltransferase 18.06 1 5 5 22 7.122E8 21.80 18.06 5 11 1566.45 18.06 5 11 299 32.7 4.37 HVO_0699 translation initiation factor aIF-2 alpha subunit 18.05 1 5 5 18 4.543E8 18.38 18.05 5 9 1041.51 18.05 5 9 266 29.5 4.46 HVO_2548 50S ribosomal protein L6 17.98 1 2 2 6 2.275E8 5.50 17.98 2 3 378.92 17.98 2 3 178 19.6 4.68 HVO_2008 archaeosine synthase 17.95 1 9 9 25 7.625E8 18.37 16.41 8 12 1427.70 17.95 9 13 585 64.9 4.81 HVO_0429 archaemetzincin 17.92 1 2 2 6 1.272E8 2.84 17.92 2 3 275.82 17.92 2 3 173 19.3 6.54 HVO_A0092 acyl-CoA dehydrogenase 17.85 1 6 6 14 7.691E7 6.75 17.85 6 7 481.96 17.85 6 7 381 42.2 4.83 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 17.84 1 3 3 14 5.254E8 15.00 17.84 3 7 1093.50 17.84 3 7 269 28.3 4.49 HVO_0414 peptidase M24 family protein 17.80 1 3 3 8 9.362E7 2.50 17.80 3 4 218.04 17.80 3 4 382 39.4 4.82 HVO_2614 uridine phosphorylase 17.77 1 3 3 18 1.617E9 17.24 17.77 3 9 1253.53 17.77 3 9 242 25.8 4.30 HVO_2923 proteasome alpha subunit 17.67 1 3 4 10 7.162E7 12.77 17.67 4 5 494.19 17.67 4 5 249 26.7 4.39 HVO_A0087 fumarylacetoacetase family protein 17.65 1 4 4 15 3.991E8 15.50 17.65 4 8 951.31 17.65 4 7 289 32.0 4.21 HVO_2168 AAA-type ATPase (MoxR subfamily) 17.63 1 5 5 16 2.406E8 14.10 17.63 5 8 936.83 17.63 5 8 329 35.9 4.54 HVO_1139 squalene synthase 17.60 1 4 4 16 1.324E8 17.65 17.60 4 8 1037.58 17.60 4 8 358 39.7 4.54 HVO_1625 conserved hypothetical protein 17.58 1 6 6 17 2.073E8 22.92 14.83 5 8 1479.19 12.54 5 9 654 70.1 4.04 HVO_2350 YyaL family protein 17.57 1 6 6 16 1.684E8 6.15 17.57 6 8 605.41 17.57 6 8 552 58.8 4.59 HVO_2600 methionyl aminopeptidase 17.57 1 7 7 17 2.855E8 10.27 8.78 4 6 1144.98 17.57 7 11 296 32.3 4.41 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 17.54 1 4 4 10 6.137E7 6.00 17.54 4 5 454.35 17.54 4 5 268 27.9 4.87 HVO_0600 ACT domain protein 17.51 1 3 3 8 1.291E8 2.63 17.51 3 4 398.99 17.51 3 4 177 19.2 4.44 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 17.46 1 6 6 15 2.591E8 15.00 17.46 6 8 810.85 17.46 6 7 378 39.8 4.45 HVO_1723 DNA repair helicase Rad25 17.27 1 8 8 21 3.463E8 16.17 12.66 6 10 1199.09 17.27 8 11 695 76.8 4.69 HVO_0179 Lrp/AsnC family transcription regulator / TrkA domain protein 17.24 1 3 3 6 1.140E8 2.69 17.24 3 3 256.86 17.24 3 3 261 28.0 4.58 HVO_1725 Orc1-type DNA replication protein 17.21 1 6 8 18 8.270E7 11.87 13.22 6 8 875.16 17.21 8 10 401 44.5 5.19 HVO_2960 dihydrolipoamide S-acyltransferase 17.08 1 7 7 37 2.210E8 35.29 17.08 7 18 2323.23 17.08 7 19 521 54.9 4.40 HVO_2793 conserved hypothetical protein 17.06 1 2 2 6 6.609E7 3.73 17.06 2 3 216.20 17.06 2 3 252 27.1 4.46 HVO_1175 DUF2110 family protein 16.89 1 3 3 13 1.245E9 11.34 16.89 3 6 829.76 16.89 3 7 225 24.4 4.63 HVO_1083 glucose 1-dehydrogenase 16.81 1 3 3 5 4.995E7 5.09 9.80 2 2 244.20 16.81 3 3 357 39.0 4.73 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 16.81 1 4 4 12 1.174E8 17.39 16.81 4 6 955.94 16.81 4 6 345 36.9 4.68 HVO_0853 DNA double-strand break repair protein Mre11 16.78 1 6 6 18 2.115E8 17.16 12.02 4 8 1122.41 16.78 6 10 441 48.1 4.39 HVO_0795 transcription initiation factor TFB 16.72 1 5 5 18 2.457E8 9.89 16.72 5 9 807.06 16.72 5 9 335 37.4 5.59 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 16.71 1 4 4 8 1.231E8 7.33 10.97 3 4 527.66 12.27 3 4 383 41.9 4.21 HVO_0826 peptidase M42 family protein 16.67 1 3 3 8 6.581E7 8.77 16.67 3 4 463.31 16.67 3 4 348 37.7 4.54 HVO_1567 conserved hypothetical protein 16.60 1 3 3 10 3.755E8 11.09 16.60 3 5 628.26 16.60 3 5 235 25.7 4.36 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 16.54 1 5 5 12 2.326E8 4.01 11.55 4 5 550.03 16.54 5 7 381 40.5 4.51 HVO_1685 conserved hypothetical protein 16.46 1 7 7 21 1.913E8 10.33 16.46 7 11 951.71 16.46 7 10 492 54.5 5.74 HVO_0818 threonine synthase 16.45 1 5 5 14 3.148E8 16.90 16.45 5 7 918.30 16.45 5 7 389 40.8 4.31 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 16.41 1 0 8 34 7.550E8 34.59 16.15 7 16 2329.82 16.41 8 18 384 42.4 5.40 HVO_1823 UspA domain protein 16.34 1 2 2 4 4.903E7 4.49 16.34 2 2 163.53 16.34 2 2 153 16.4 4.60 HVO_2712 3'-5' RNA ligase 16.26 1 7 7 21 2.021E8 7.83 16.26 7 10 949.21 16.26 7 11 486 53.4 4.92 HVO_2948 phenylalanine--tRNA ligase alpha subunit 16.23 1 4 4 26 5.208E8 18.65 16.23 4 13 1305.31 16.23 4 13 499 55.1 4.41 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 16.16 1 6 6 21 2.634E8 5.40 16.16 6 11 754.85 14.01 5 10 464 53.1 4.54 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 16.07 1 3 3 6 6.763E7 2.73 16.07 3 3 259.95 16.07 3 3 280 30.0 4.92 HVO_2554 50S ribosomal protein L14 15.91 1 3 3 10 1.240E8 6.38 15.91 3 5 525.95 15.91 3 5 132 14.2 9.76 HVO_1048 phosphoribosylformylglycinamidine synthase 2 15.81 1 8 8 36 8.640E8 42.00 14.81 7 17 2603.92 15.81 8 19 702 72.9 4.18 4557890 keratin 5 [Homo sapiens] 15.76 1 0 10 45 9.428E8 38.89 15.76 10 22 2734.78 15.76 10 23 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 15.76 1 0 10 45 9.428E8 38.89 15.76 10 22 2734.78 15.76 10 23 590 62.4 8.06 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 15.61 1 2 2 6 7.779E8 3.85 15.61 2 3 258.43 15.61 2 3 237 26.2 4.70 HVO_1300 triosephosphate isomerase 15.42 1 3 3 35 2.190E9 46.75 15.42 3 18 2920.39 15.42 3 17 214 21.3 4.26 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 15.38 1 3 3 11 3.856E8 10.32 15.38 3 5 462.21 15.38 3 6 377 39.2 4.18 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 15.35 1 3 3 8 8.524E7 3.79 15.35 3 4 344.93 15.35 3 4 241 26.1 4.58 HVO_2001 tRNA-guanine(15) transglycosylase 15.31 1 4 4 14 1.411E8 13.16 15.31 4 7 835.24 15.31 4 7 516 56.3 4.59 HVO_B0058 precorrin-3B C17-methyltransferase 15.31 1 3 3 12 1.071E8 8.96 15.31 3 6 705.89 15.31 3 6 294 31.8 4.40 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 15.29 1 0 2 4 8.923E8 284.65 15.29 2 4 85 10.0 5.94 HVO_1097 diaminopimelate epimerase 15.28 1 3 3 11 1.251E8 15.07 15.28 3 6 638.48 15.28 3 5 288 29.9 4.48 HVO_0837 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 15.23 1 3 3 6 4.083E7 3.96 15.23 3 3 265.43 15.23 3 3 243 24.8 4.48 HVO_0896 acyl-CoA synthetase 15.19 1 7 7 22 1.365E8 20.47 13.15 6 11 1130.64 12.59 6 11 540 59.8 4.56 HVO_1374 acyl-CoA synthetase 15.19 1 8 8 29 1.353E9 20.49 15.19 7 14 1760.63 15.19 8 15 553 61.1 4.50 HVO_2777 30S ribosomal protein S9 15.15 1 2 2 6 8.425E7 6.00 15.15 2 3 320.85 15.15 2 3 132 14.7 9.74 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 15.14 1 6 6 17 2.883E8 15.39 15.14 6 9 879.80 13.72 5 8 634 66.1 4.54 HVO_1578 probable NADH dehydrogenase 15.11 1 4 4 13 3.325E8 12.87 15.11 4 7 631.46 11.59 3 6 397 42.8 4.40 HVO_1250 redoxin domain protein 14.97 1 2 2 2 1.403E8 261.31 14.97 2 2 187 20.5 4.03 HVO_2763 homolog to ribonuclease Z 14.92 1 3 3 13 2.454E8 4.00 14.92 3 6 658.87 14.92 3 7 248 26.6 4.53 HVO_1683 4-alpha-glucanotransferase 14.92 1 8 8 27 2.212E8 9.57 14.92 8 13 1123.48 14.92 8 14 496 56.3 4.45 HVO_A0583 IclR family transcription regulator 14.84 1 4 4 11 9.073E7 6.87 10.94 3 5 574.13 14.84 4 6 256 27.9 5.07 HVO_1375 O-succinylbenzoic acid--CoA ligase 14.82 1 7 7 20 1.336E8 18.18 14.82 7 10 877.02 14.82 7 10 614 64.7 4.28 HVO_2427 replication factor C large subunit 14.75 1 6 6 20 7.000E7 21.94 14.75 6 10 1273.32 14.75 6 10 488 53.4 4.67 HVO_1179 homolog to NAD kinase 14.69 1 3 3 5 7.985E7 2.86 8.47 2 2 338.09 14.69 3 3 354 36.7 4.60 HVO_0402 DUF124 family protein 14.67 1 2 2 5 1.648E8 5.48 14.67 2 2 296.32 14.67 2 3 225 24.0 4.58 HVO_0156 "tRNA (guanine(10),N(2))-dimethyltransferase" 14.64 1 3 3 8 3.945E7 1.92 14.64 3 4 238.68 14.64 3 4 321 34.2 5.25 HVO_0541 aconitate hydratase 14.61 1 10 10 38 6.200E8 15.83 14.61 10 19 1712.25 14.61 10 19 938 102.1 4.40 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 14.61 1 4 4 16 1.791E8 12.76 14.61 4 8 906.79 14.61 4 8 349 37.0 4.70 HVO_A0586 sugar nucleotidyltransferase 14.60 1 5 5 14 1.688E8 9.59 14.60 5 7 860.70 14.60 5 7 411 43.7 4.69 HVO_1236 acyl-CoA synthetase 14.58 1 7 7 31 2.869E8 28.15 14.58 6 15 1737.48 14.58 7 16 535 59.1 4.60 HVO_2918 thymidylate synthase 14.46 1 3 3 12 1.878E8 12.65 14.46 3 6 789.61 14.46 3 6 332 37.5 4.61 HVO_1337 rpa-associated protein 14.45 1 6 6 28 1.065E9 22.31 14.45 6 13 1403.05 14.45 6 15 623 64.8 3.68 HVO_1928 5-formyltetrahydrofolate cyclo-ligase 14.40 1 3 3 8 3.852E7 8.64 14.40 3 4 394.70 14.40 3 4 243 26.5 4.69 HVO_1058 TrkA domain protein 14.38 1 6 6 21 2.857E8 12.24 14.38 6 11 1082.45 12.13 5 10 445 47.7 4.35 HVO_2479 2-phospho-L-lactate transferase 14.24 1 4 4 12 1.423E8 12.10 14.24 4 6 712.54 14.24 4 6 330 34.7 4.32 HVO_2702 alpha/beta hydrolase fold protein 14.23 1 3 3 14 1.877E8 5.83 14.23 3 7 579.32 14.23 3 7 260 28.0 4.53 HVO_1809 isochorismatase family protein 14.21 1 2 2 6 1.595E8 1.69 14.21 2 3 230.93 14.21 2 3 190 21.0 4.55 21961227 Keratin 6B [Homo sapiens] 14.18 1 0 10 52 9.983E8 52.96 14.01 9 25 3478.00 14.18 10 27 564 60.0 8.00 HVO_2761 mevalonate kinase 14.17 1 4 4 9 4.423E7 7.88 14.17 4 5 341.75 14.17 4 4 367 38.2 4.31 HVO_0452 leucine--tRNA ligase 14.09 1 12 12 36 2.776E8 24.99 14.09 12 17 2370.08 14.09 12 19 958 109.5 4.37 HVO_0017 conserved hypothetical protein 14.06 1 2 2 6 4.967E8 5.91 14.06 2 3 461.61 14.06 2 3 192 21.9 4.50 HVO_A0550 receiver/sensor box histidine kinase 14.01 1 8 9 19 5.595E7 13.85 10.17 8 9 899.51 14.01 9 10 885 95.9 4.46 HVO_0123 signal recognition particle 54K protein 13.98 1 5 5 22 2.630E8 19.90 11.83 4 10 1419.09 13.98 5 12 465 50.9 4.50 HVO_0868 NAD-dependent epimerase/dehydratase 13.98 1 4 4 9 1.234E8 3.66 10.33 3 4 293.81 13.98 4 5 329 36.1 4.55 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 13.92 1 6 6 20 1.006E8 9.11 13.92 6 11 736.56 13.92 6 9 661 71.0 4.35 HVO_0867 HD family hydrolase 13.91 1 3 3 16 1.425E8 8.45 13.91 3 8 903.97 13.91 3 8 230 26.2 4.78 HVO_0454 ornithine cyclodeaminase 13.90 1 3 3 6 8.489E7 4.34 13.90 3 3 313.13 13.90 3 3 331 35.6 4.23 HVO_1299 HTH domain protein 13.87 1 2 2 7 1.414E8 5.20 13.87 2 4 316.22 13.87 2 3 173 18.9 4.84 HVO_C0044 PLD domain protein 13.81 1 3 3 7 7.024E7 4.03 7.51 2 3 361.77 13.81 3 4 333 36.4 4.94 HVO_1610 conserved hypothetical protein 13.78 1 2 2 4 4.040E7 2.75 13.78 2 2 177.60 13.78 2 2 283 30.5 4.55 HVO_1500 1-phosphofructokinase 13.77 1 3 3 7 1.116E8 5.00 10.16 2 3 244.25 13.77 3 4 305 32.0 4.51 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 13.73 1 4 4 9 3.540E8 4.03 9.33 3 4 513.67 13.73 4 5 386 42.1 4.49 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 13.72 1 4 4 11 2.103E8 1.94 10.97 3 5 361.63 13.72 4 6 401 43.1 4.60 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 6 3.089E8 0.00 13.66 2 2 283.48 13.66 2 4 183 20.0 4.21 HVO_2809 succinate dehydrogenase subunit B (iron-sulfur protein) 13.65 1 4 4 7 1.094E8 1.89 13.65 4 4 214.39 9.90 3 3 293 33.9 5.27 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 13.61 1 4 4 24 2.133E8 26.98 13.61 4 12 1430.59 13.61 4 12 360 39.5 4.31 HVO_B0052 PQQ repeat protein 13.59 1 5 5 16 1.092E8 15.03 13.59 5 8 1043.83 13.59 5 8 412 44.1 5.48 HVO_1979 tRNA pseudouridine synthase Pus10 13.58 1 5 5 22 7.869E8 20.89 13.58 5 11 1522.91 13.58 5 11 427 46.9 4.39 HVO_2681 HTH domain protein 13.58 1 2 2 3 3.543E7 162.07 13.58 2 3 265 28.8 4.64 HVO_0572 lipoate-protein ligase 13.45 1 3 3 6 1.270E8 9.05 13.45 3 3 477.95 13.45 3 3 275 30.5 4.84 HVO_B0001 Orc1-type DNA replication protein 13.41 1 4 6 11 1.261E8 4.29 11.22 5 5 499.04 13.41 6 6 410 45.8 5.33 HVO_1129 conserved hypothetical protein 13.33 1 3 4 11 1.663E8 8.80 13.33 4 6 485.59 12.05 3 5 390 43.0 4.44 HVO_A0388 Lrp/AsnC family transcription regulator 13.22 1 2 2 3 7.511E7 1.69 13.22 2 3 174 20.1 4.86 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 13.16 1 4 4 17 1.857E8 14.26 9.62 3 7 1220.22 13.16 4 10 395 42.4 4.54 HVO_1323 "shikimate kinase, archaeal-type" 13.15 1 3 3 14 2.990E8 12.98 13.15 3 8 851.13 9.00 2 6 289 29.5 4.30 HVO_1150 IS200-type transposase 13.08 1 2 2 6 1.062E8 0.00 13.08 2 3 263.96 13.08 2 3 130 14.7 5.49 HVO_0100 NMD3 family protein 13.07 1 3 3 8 1.311E8 1.82 13.07 3 4 299.39 13.07 3 4 375 41.6 4.46 HVO_2244 fumarylacetoacetase family protein 12.97 1 2 2 6 3.681E7 4.14 12.97 2 3 162.23 12.97 2 3 239 26.1 4.07 HVO_A0010 conserved hypothetical protein 12.96 1 2 2 3 1.870E7 136.96 12.96 2 3 270 30.6 4.34 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 12.86 1 4 4 14 1.863E8 2.10 12.86 4 7 364.65 12.86 4 7 482 50.6 4.31 HVO_1559 HTH/CBS domain protein 12.85 1 2 2 6 3.783E7 3.45 12.85 2 3 281.08 12.85 2 3 179 19.5 4.48 HVO_B0200 malate synthase 12.84 1 3 3 12 3.756E8 12.49 12.84 3 6 713.14 12.84 3 6 436 48.3 4.30 HVO_0194 Orc1-type DNA replication protein 12.83 1 5 5 9 1.467E8 1.78 9.09 4 4 411.06 12.83 5 5 374 42.2 4.94 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 12.66 1 4 4 17 1.375E8 14.82 6.20 2 8 1064.70 12.66 4 9 403 41.1 4.73 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 12.56 1 4 4 20 6.085E8 14.83 12.56 4 10 1030.60 12.56 4 10 430 44.2 4.37 HVO_0044 acetylglutamate kinase 12.54 1 3 3 11 4.498E8 9.01 12.54 3 6 683.51 12.54 3 5 327 33.2 4.49 HVO_B0060 precorrin-4 C11-methyltransferase 12.54 1 2 2 14 3.549E8 2.02 12.54 2 7 538.06 12.54 2 7 279 29.7 4.22 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 12.53 1 4 4 14 2.694E8 8.50 12.53 4 7 593.99 12.53 4 7 383 42.0 4.49 HVO_1169 "probable glycosyltransferase, type 1" 12.50 1 3 3 5 6.503E7 1.68 12.50 3 3 134.58 8.70 2 2 368 40.8 4.73 HVO_B0111 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 12.47 1 4 4 10 9.772E7 8.21 12.47 4 5 459.57 12.47 4 5 401 44.2 4.54 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 12.41 1 0 9 38 9.428E8 36.44 12.23 8 18 2508.28 12.41 9 20 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 12.41 1 0 9 38 9.428E8 36.44 12.23 8 18 2508.28 12.41 9 20 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 12.41 1 0 9 38 9.428E8 36.44 12.23 8 18 2508.28 12.41 9 20 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 12.41 1 0 9 38 9.428E8 36.44 12.23 8 18 2508.28 12.41 9 20 564 60.0 7.72 HVO_0135 RIO-type serine/threonine protein kinase 12.41 1 4 4 11 7.891E7 6.48 9.66 3 5 738.20 12.41 4 6 290 33.0 4.81 HVO_0551 DNA mismatch repair protein MutL 12.38 1 7 7 23 2.391E8 22.45 12.38 7 11 1211.73 12.38 7 12 735 78.7 4.50 HVO_B0115 fumarylacetoacetase family protein 12.37 1 3 3 12 3.528E8 13.28 12.37 3 6 829.25 12.37 3 6 283 30.3 4.21 HVO_2945 valine--tRNA ligase 12.30 1 10 10 39 6.399E8 24.49 10.80 9 18 2750.57 12.30 10 21 870 98.9 4.36 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 12.21 1 3 3 10 1.393E8 6.78 8.72 2 4 778.53 12.21 3 6 344 37.0 4.55 HVO_0689 chromosome segregation protein Smc 11.94 1 13 13 35 2.828E8 20.05 11.94 13 18 1610.97 11.94 13 17 1240 138.1 4.39 HVO_1391 NUDIX family hydrolase 11.92 1 2 2 6 8.427E7 5.36 11.92 2 3 334.86 11.92 2 3 151 17.4 5.01 HVO_2648 phosphoglycerate dehydrogenase 11.91 1 3 3 12 1.848E8 9.05 11.91 3 6 699.69 11.91 3 6 319 34.2 4.64 HVO_1893 non-canonical purine NTP pyrophosphatase 11.90 1 2 2 4 4.233E7 2.36 11.90 2 2 246.44 11.90 2 2 210 23.0 4.58 HVO_2068 "FtsZ family protein, type III" 11.89 1 3 3 10 2.876E8 15.03 11.89 3 5 1027.29 11.89 3 5 370 38.7 4.49 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 11.81 1 8 8 26 2.655E8 21.18 9.07 6 12 1270.19 11.81 8 14 838 89.1 4.65 HVO_2891 thymidine kinase 11.79 1 2 2 6 6.042E7 3.45 11.79 2 3 398.77 11.79 2 3 195 21.4 4.63 HVO_2610 deoxyribose-phosphate aldolase 11.79 1 2 2 5 1.080E8 380.68 11.79 2 5 212 21.9 4.23 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 11.78 1 4 4 10 1.490E8 1.64 11.78 4 5 284.51 11.78 4 5 348 36.7 4.69 HVO_0228 ParA domain protein 11.74 1 2 2 3 3.260E8 323.52 11.74 2 3 247 24.6 4.16 HVO_1279 dihydrofolate reductase 11.73 1 2 2 6 3.166E7 1.84 11.73 2 3 169.59 11.73 2 3 162 18.0 4.58 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 6 7.980E8 6.56 11.64 2 3 294.71 11.64 2 3 189 20.3 4.22 HVO_2250 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 11.60 1 2 2 4 9.227E7 2.00 11.60 2 2 148.80 11.60 2 2 181 19.5 4.28 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 11.59 1 3 3 8 8.914E7 4.20 11.59 3 4 369.70 11.59 3 4 328 36.1 4.67 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 11.57 1 0 6 22 6.886E8 19.11 11.57 6 11 1262.76 11.57 6 11 432 48.1 5.02 HVO_0741 DNA-directed DNA polymerase X 11.51 1 4 4 9 1.020E8 4.57 8.25 3 4 345.86 11.51 4 5 582 62.6 4.44 HVO_2272 conserved hypothetical protein 11.45 1 1 2 2 8.585E7 0.00 11.45 2 2 166 19.8 4.69 HVO_A0547 DUF1028 family protein 11.41 1 4 4 8 1.147E8 4.01 11.41 4 4 271.94 7.51 3 4 333 35.2 4.16 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 11.39 1 4 4 16 4.192E8 9.27 6.39 2 6 1224.39 11.39 4 10 360 38.5 4.45 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 11.37 1 3 4 18 5.936E8 7.51 11.37 4 9 954.41 11.37 4 9 299 32.0 4.53 HVO_1235 creatininase 11.36 1 3 3 10 9.935E7 10.03 11.36 3 5 607.34 11.36 3 5 264 29.2 4.84 HVO_1098 diaminopimelate decarboxylase 11.33 1 4 4 12 3.225E8 7.95 11.33 4 6 552.51 11.33 4 6 415 44.4 5.02 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 11.29 1 3 3 15 4.885E8 12.48 9.92 2 7 1160.20 11.29 3 8 363 39.7 4.25 HVO_1249 conserved hypothetical protein 11.27 1 2 2 4 1.223E8 1.61 11.27 2 2 162.52 11.27 2 2 142 16.4 5.20 HVO_A0180 SMC-like protein Sph1 11.13 1 5 6 15 1.098E8 7.36 11.13 6 8 436.50 10.29 5 7 593 66.4 4.58 HVO_A0553 adenosylcobyric acid synthase 11.13 1 3 3 6 5.294E7 1.66 8.01 2 2 168.38 11.13 3 4 512 52.6 4.50 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 11.11 1 4 4 16 1.680E8 19.14 11.11 4 8 1090.90 11.11 4 8 423 43.9 4.31 HVO_1562 proteasome beta subunit 11.11 1 3 3 14 1.227E8 11.52 11.11 3 7 790.43 11.11 3 7 243 26.0 4.63 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 11.06 1 2 2 7 2.549E8 2.37 11.06 2 4 236.28 11.06 2 3 208 22.6 4.36 HVO_2503 kynureninase 11.06 1 4 4 14 7.176E7 4.27 8.24 3 6 892.53 11.06 4 8 425 46.0 4.54 HVO_2158 malic enzyme (NADP) 10.92 1 0 4 17 3.379E8 17.76 10.92 4 9 959.09 10.92 4 8 751 81.4 4.55 HVO_2056 "probable epimerase (homolog to dTDP-4-dehydrorhamnose 3,5-epimerase)" 10.90 1 2 2 4 3.701E7 3.84 10.90 2 2 169.38 10.90 2 2 156 18.3 4.55 HVO_2871 pyridoxal phosphate-dependent aminotransferase 10.89 1 4 4 16 1.215E8 11.72 10.89 4 8 712.60 10.89 4 8 450 49.1 4.70 HVO_1077 diphthamide biosynthesis protein Dph6 10.83 1 2 2 7 1.048E8 2.38 10.83 2 3 357.01 10.83 2 4 240 26.0 4.15 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 10.83 1 2 2 8 3.272E8 9.75 10.83 2 4 658.19 10.83 2 4 277 30.6 4.30 HVO_0328 NAD-dependent epimerase/dehydratase 10.81 1 3 3 10 5.126E7 3.79 10.81 3 5 327.32 10.81 3 5 296 31.7 5.07 HVO_0464 threonine ammonia-lyase 10.67 1 4 4 8 6.570E7 2.96 10.67 4 4 339.64 10.67 4 4 403 43.7 4.72 HVO_1812 conserved hypothetical protein 10.67 1 4 4 6 9.941E7 5.75 10.67 4 4 169.47 5.60 2 2 375 40.5 4.50 386849 keratin type II 10.66 1 0 7 23 9.007E8 22.04 10.48 6 11 1487.19 10.66 7 12 563 59.9 7.94 HVO_1373 acyl-CoA dehydrogenase 10.44 1 3 3 7 9.311E7 5.25 10.44 3 4 389.14 6.27 2 3 383 42.5 4.61 HVO_0854 DNA double-strand break repair ATPase Rad50 10.41 1 9 9 20 6.359E8 9.97 9.63 8 9 859.61 10.41 9 11 893 100.0 4.58 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 10.30 1 3 3 6 6.125E7 2.58 10.30 3 3 286.31 10.30 3 3 398 43.4 4.37 HVO_0042 acetylornithine deacetylase 10.24 1 3 3 7 3.396E8 7.65 7.87 2 3 551.44 10.24 3 4 381 41.0 4.34 HVO_1746 DUF2800 family protein 10.22 1 1 2 4 1.014E8 2.36 10.22 2 2 151.41 10.22 2 2 323 36.5 4.37 HVO_0322 MinD/ParA domain protein 10.15 1 3 3 17 3.207E8 16.21 10.15 3 8 1063.78 10.15 3 9 581 58.8 3.70 HVO_2873 flap endonuclease Fen1 10.12 1 2 2 2 5.806E7 92.69 10.12 2 2 326 36.4 4.40 HVO_1668 gamma-glutamylcysteine synthetase 10.06 1 4 4 12 3.627E7 6.16 10.06 4 6 583.33 10.06 4 6 358 39.9 4.72 HVO_0014 ATP-dependent DNA helicase Hel308a 10.04 1 9 9 27 1.366E8 12.11 9.07 8 13 1565.87 10.04 9 14 827 90.3 4.67 HVO_0558 SAMP-activating enzyme E1 10.00 1 2 2 8 1.061E8 4.14 10.00 2 4 439.01 10.00 2 4 270 28.7 4.35 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 9 4.449E8 4.13 10.00 2 4 475.65 10.00 2 5 190 21.0 4.74 HVO_0719 transcription elongation factor Spt5/NusG 10.00 1 2 2 4 1.976E8 360.08 10.00 2 4 150 16.3 4.50 HVO_1936 F420-0:gamma-glutamyl ligase 9.96 1 2 2 7 1.417E8 5.25 9.96 2 4 294.29 9.96 2 3 251 27.4 4.68 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 9.87 1 2 2 8 1.405E8 10.29 9.87 2 4 452.71 9.87 2 4 446 47.9 4.39 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 9.84 1 4 4 11 1.097E8 2.66 9.84 4 6 461.45 9.84 4 5 386 40.0 4.68 HVO_0220 ATP-dependent DNA helicase MCM 9.83 1 6 6 16 7.010E7 9.60 9.83 6 8 673.56 9.83 6 8 702 78.8 4.73 HVO_0311 A-type ATP synthase subunit I 9.82 1 5 5 15 2.087E8 8.09 9.82 5 8 531.08 9.82 5 7 733 79.5 4.41 HVO_2906 tRNA (cytidine/uridine-2'-O-)-methyltransferase 9.82 1 2 2 4 5.000E7 2.39 9.82 2 2 166.46 9.82 2 2 275 30.6 4.58 HVO_A0305 methylmalonate-semialdehyde dehydrogenase 9.82 1 3 3 9 8.122E7 0.00 9.82 3 5 185.39 9.82 3 4 489 52.1 4.59 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 9.79 1 3 3 7 1.725E8 4.76 9.79 3 4 325.68 6.64 2 3 286 30.8 4.46 HVO_B0055 conserved hypothetical protein 9.78 1 3 3 10 2.562E8 8.71 9.78 3 5 564.28 9.78 3 5 225 23.9 4.69 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 9.75 1 3 3 8 4.593E7 3.46 9.75 3 4 278.60 9.75 3 4 359 39.4 4.91 HVO_0019 probable S-adenosylmethionine-dependent methyltransferase (homolog to 24-sterol C-methyltransferase) 9.73 1 2 2 8 1.028E8 7.77 9.73 2 4 424.63 9.73 2 4 226 25.6 4.64 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 9.68 1 3 3 9 9.151E7 8.00 9.68 3 5 530.40 5.47 2 4 475 49.3 4.49 HVO_A0476 conserved hypothetical protein 9.67 1 3 3 8 4.493E7 2.07 9.67 3 4 305.73 9.67 3 4 331 35.4 4.26 HVO_B0266 glutamate dehydrogenase (NAD) 9.66 1 4 4 11 1.557E8 15.39 9.66 4 6 752.99 7.36 3 5 435 47.3 4.63 HVO_0968 NADH dehydrogenase-like complex subunit CD 9.57 1 0 6 32 1.717E9 22.48 9.57 6 16 1849.39 9.57 6 16 564 63.3 4.60 HVO_1413 probable NADH dehydrogenase 9.55 1 3 3 9 9.585E7 5.75 9.55 3 5 526.31 9.55 3 4 377 39.7 4.67 HVO_A0486 hydrogenase expression/formation protein 9.52 1 2 2 8 5.415E7 7.42 9.52 2 4 383.84 9.52 2 4 336 33.8 4.06 HVO_2501 alpha/beta hydrolase fold protein 9.49 1 2 2 8 6.527E7 7.31 9.49 2 4 385.79 9.49 2 4 316 35.3 5.72 HVO_1381 probable methyltransferase 9.46 1 2 2 4 0.000E0 2.65 9.46 2 2 148.02 9.46 2 2 222 23.9 4.46 HVO_2640 conserved hypothetical protein 9.39 1 3 3 8 4.640E7 3.63 9.39 3 4 293.26 6.15 2 4 309 33.9 4.56 HVO_C0067 FAD-dependent oxidoreductase 9.34 1 3 3 7 1.138E8 6.02 5.05 2 3 506.69 9.34 3 4 396 42.7 4.30 HVO_2229 flavin-containing amine-oxidoreductase 9.30 1 2 2 6 1.383E8 2.52 9.30 2 3 182.64 9.30 2 3 344 37.9 4.92 HVO_1055 TrkA domain protein 9.29 1 2 2 6 5.146E7 4.96 9.29 2 3 317.88 9.29 2 3 226 24.4 4.39 HVO_0648 DUF2070 family protein 9.26 1 2 2 2 0.000E0 0.00 9.26 2 2 637 67.7 4.77 HVO_B0040 IclR family transcription regulator 9.16 1 2 2 4 9.469E7 2.16 9.16 2 2 124.16 9.16 2 2 251 27.2 5.30 HVO_0069 sulfatase 9.13 1 4 4 7 5.014E7 1.73 4.27 2 2 432.83 9.13 4 5 515 57.4 4.35 HVO_0824 "probable glycosyltransferase, type 1" 9.09 1 3 3 8 6.735E7 6.61 9.09 3 4 409.37 9.09 3 4 352 39.6 5.08 HVO_2605 MiaB-like tRNA modifying enzyme 9.09 1 3 3 5 1.992E7 1.89 9.09 3 3 145.12 4.20 2 2 429 47.4 5.03 HVO_2932 GTP-binding protein 9.09 1 3 3 14 1.471E8 1.73 9.09 3 7 583.17 9.09 3 7 396 43.5 4.51 HVO_2835 histidine kinase 9.06 1 1 2 4 1.574E8 0.00 9.06 2 2 44.68 9.06 2 2 342 36.2 4.63 HVO_1740 conserved hypothetical protein 9.05 1 2 2 8 4.149E7 2.62 9.05 2 4 436.15 9.05 2 4 210 24.4 4.49 HVO_0001 Orc1-type DNA replication protein 9.04 1 3 4 8 5.693E7 6.63 9.04 4 4 384.45 9.04 4 4 564 62.1 4.39 HVO_0760 "probable glycosyltransferase, type 2" 8.97 1 3 3 10 1.069E8 2.04 8.97 3 5 519.96 8.97 3 5 368 40.7 4.82 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 8.81 1 2 2 6 5.584E7 4.40 8.81 2 3 291.68 8.81 2 3 329 36.3 4.49 HVO_C0077 sarcosine oxidase 8.79 1 2 2 3 1.136E8 2.47 8.79 2 3 387 42.9 4.70 HVO_2507 Lrp/AsnC family transcription regulator 8.76 1 2 2 2 7.994E7 140.65 8.76 2 2 137 15.5 4.67 27894337 keratin 20 [Homo sapiens] 8.73 1 1 3 10 1.022E8 8.39 8.73 3 5 547.23 8.73 3 5 424 48.5 5.69 HVO_C0042 helicase domain protein 8.71 1 10 10 29 2.071E8 17.64 8.16 9 14 1467.64 8.71 10 15 1274 144.4 4.67 HVO_A0591 DICT domain protein 8.70 1 2 2 5 4.302E7 0.00 8.70 2 2 215.33 8.70 2 3 253 27.8 4.50 HVO_0305 electron transfer flavoprotein beta subunit 8.68 1 2 2 8 4.668E8 5.84 8.68 2 4 730.24 8.68 2 4 265 28.5 4.04 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 8.66 1 4 4 9 9.097E7 3.85 8.66 4 4 340.45 8.66 4 5 439 47.2 4.59 HVO_1995 conserved hypothetical protein 8.64 1 2 2 2 5.183E7 4.69 8.64 2 2 243 26.5 4.39 HVO_1368 probable metallo-beta-lactamase family hydrolase 8.61 1 2 2 5 2.300E8 552.53 8.61 2 5 267 29.3 4.49 HVO_0733 transcription initiation factor TFB 8.59 1 0 3 11 7.236E8 8.10 8.59 3 6 680.50 8.59 3 5 326 37.2 6.00 HVO_3000 DNA ligase (NAD) 8.58 1 4 4 19 8.103E8 18.56 8.58 4 9 1165.99 8.58 4 10 699 75.8 4.50 HVO_1087 UspA domain protein 8.51 1 2 2 8 1.380E8 6.75 8.51 2 4 523.85 8.51 2 4 141 15.2 4.98 HVO_2321 bacterial-type DNA primase DnaG 8.47 1 4 4 11 1.619E8 5.98 8.47 4 6 562.70 6.99 3 5 472 49.4 4.36 HVO_B0277 HTH domain protein 8.40 1 2 2 3 1.055E8 241.89 8.40 2 3 262 29.5 4.50 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 8.33 1 5 5 18 5.272E8 11.16 8.33 5 9 1079.72 8.33 5 9 612 67.3 4.16 HVO_B0038A D-xylonate dehydratase 8.25 1 1 3 13 4.862E8 9.08 8.25 3 7 720.02 4.61 2 6 412 45.5 4.55 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 8.24 1 3 3 12 5.545E7 6.40 8.24 3 6 539.01 8.24 3 6 437 47.1 4.72 HVO_1008 GFO family oxidoreductase 8.13 1 2 2 6 4.784E7 2.00 8.13 2 3 253.92 8.13 2 3 332 36.0 4.72 HVO_A0342 IclR family transcription regulator 8.12 1 2 2 2 2.589E7 0.00 8.12 2 2 271 30.6 5.19 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 8.05 1 3 3 5 1.156E8 1.91 8.05 3 3 133.95 3.94 2 2 584 63.3 4.79 HVO_0326 CTP-dependent riboflavin kinase 8.02 1 2 2 6 1.263E8 6.00 8.02 2 3 449.97 8.02 2 3 237 25.9 4.55 HVO_B0233 alpha-L-arabinofuranosidase 8.02 1 4 4 7 1.354E8 3.87 8.02 4 4 247.79 5.68 3 3 511 57.5 4.39 HVO_0236 tRNA (guanine(26)-N(2))-dimethyltransferase 7.98 1 2 2 4 2.069E7 4.87 7.98 2 2 229.09 7.98 2 2 376 40.9 4.97 HVO_1117 HTH-10 family transcription regulator 7.98 1 2 2 5 2.480E7 2.46 7.98 2 3 275.98 7.98 2 2 213 23.3 4.56 HVO_0675 pantoate kinase 7.94 1 2 2 6 8.144E7 7.49 7.94 2 3 397.27 7.94 2 3 277 27.8 4.54 HVO_1568 alpha/beta hydrolase fold protein 7.94 1 2 2 12 1.071E8 10.61 7.94 2 6 696.16 7.94 2 6 277 29.4 4.94 HVO_B0223 conserved hypothetical protein 7.94 1 2 2 4 2.563E7 1.83 7.94 2 2 224.87 7.94 2 2 277 29.8 4.51 HVO_2108 IclR family transcription regulator 7.91 1 2 2 4 3.300E7 0.00 7.91 2 2 202.71 7.91 2 2 253 28.0 5.74 HVO_0590 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase 7.89 1 2 2 6 8.880E7 4.77 7.89 2 3 267.58 7.89 2 3 355 35.6 4.30 HVO_1879 enoyl-CoA hydratase 7.79 1 2 2 2 7.003E7 169.86 7.79 2 2 231 24.3 5.21 HVO_B0182 deoxyhypusine synthase 7.72 1 2 2 6 2.325E8 1.96 7.72 2 3 289.78 7.72 2 3 324 35.6 4.30 HVO_1711 glucoamylase 7.68 1 10 10 26 1.490E8 20.27 7.68 10 14 1133.26 7.68 10 12 1511 166.1 4.64 HVO_1594 tRNA/rRNA cytosine-C5-methylase 7.67 1 2 2 5 1.610E8 4.31 7.67 2 3 241.84 7.67 2 2 313 34.6 4.69 HVO_1895 KEOPS complex subunit Kae1/Bud32 7.61 1 4 4 7 7.593E7 6.21 5.98 3 3 294.20 7.61 4 4 552 59.0 5.07 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 7.56 1 3 3 9 6.136E7 4.01 7.56 3 4 258.91 7.56 3 5 410 46.0 4.89 HVO_1425 conserved hypothetical protein 7.55 1 2 2 6 6.763E7 1.80 7.55 2 3 207.16 7.55 2 3 265 30.4 4.61 HVO_2665 HpcH/HpaI aldolase family protein 7.55 1 2 2 6 8.120E7 4.33 7.55 2 3 279.99 7.55 2 3 265 28.3 4.50 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 7.38 1 3 3 8 4.236E7 6.00 7.38 3 4 351.30 7.38 3 4 420 45.0 4.86 HVO_A0331 D-galactonate dehydratase 7.29 1 2 2 3 2.136E8 325.88 7.29 2 3 384 42.8 4.83 HVO_2255 conserved hypothetical protein 7.20 1 2 2 4 5.917E7 4.67 7.20 2 2 278.06 7.20 2 2 236 27.7 5.60 HVO_B0154 receiver/sensor box histidine kinase 7.15 1 9 9 28 1.325E8 17.93 7.15 9 14 1259.31 7.15 9 14 1301 144.1 4.39 HVO_2072 S-layer glycoprotein 7.13 1 3 3 49 3.323E9 41.07 7.13 3 24 1913.52 7.13 3 25 827 85.1 3.65 HVO_1564 conserved hypothetical protein 7.07 1 3 3 5 6.093E7 2.00 7.07 3 3 170.47 4.72 2 2 509 56.5 4.65 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 6 1.432E8 5.63 7.07 2 3 386.81 7.07 2 3 297 32.3 3.98 HVO_0990 DHH family phosphoesterase 7.00 1 2 3 5 4.684E7 1.90 5.97 2 2 315.15 7.00 3 3 486 51.9 4.59 HVO_2160 conserved hypothetical protein 7.00 1 12 12 59 1.106E9 60.23 7.00 12 29 4110.71 7.00 12 30 2257 232.7 3.92 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 7 6.651E8 1.65 5.40 2 3 390.72 6.94 3 4 389 40.8 4.89 HVO_1710 alpha amylase 6.94 1 5 5 15 2.278E8 3.99 6.94 5 7 794.61 6.94 5 8 677 75.0 4.45 HVO_B0183 YgeA family protein 6.94 1 2 2 2 4.967E7 161.53 6.94 2 2 245 26.8 4.58 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 6.76 1 2 3 10 5.061E7 3.75 6.76 3 5 361.22 6.76 3 5 444 47.1 4.77 HVO_A0439 DUF2800 family protein 6.75 1 1 2 4 1.858E7 2.36 6.75 2 2 150.43 6.75 2 2 326 36.9 4.51 HVO_2071 conserved hypothetical protein 6.74 1 3 3 13 1.300E8 7.36 6.74 3 7 683.06 6.74 3 6 549 58.4 4.72 HVO_1861 thiamine-monophosphate kinase 6.73 1 2 2 6 9.991E7 5.63 6.73 2 3 299.78 6.73 2 3 297 30.8 4.32 HVO_2381 UPF0272 family protein 6.69 1 3 3 10 8.419E7 9.57 6.69 3 5 596.05 6.69 3 5 493 52.3 4.88 HVO_B0324 conserved hypothetical protein 6.68 1 3 3 11 1.577E8 6.30 6.68 3 5 759.85 6.68 3 6 449 48.0 4.58 HVO_1565 DNA ligase (ATP) 6.67 1 3 3 8 2.263E7 7.34 6.67 3 4 511.62 6.67 3 4 585 62.7 4.44 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 6.67 1 2 2 2 9.523E7 0.00 6.67 2 2 345 37.0 3.95 HVO_1419 HTH-10 family transcription regulator 6.67 1 2 2 2 7.825E7 0.00 6.67 2 2 225 25.2 4.77 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 6.62 1 4 4 8 3.363E7 5.10 6.62 4 4 394.02 6.62 4 4 740 85.6 4.70 HVO_1864 molybdopterin synthase catalytic subunit 6.51 1 2 2 4 1.209E8 0.00 6.51 2 2 112.11 6.51 2 2 261 27.9 4.41 HVO_0831 ArgK-type transport ATPase 6.45 1 2 2 6 7.730E7 8.16 6.45 2 3 381.06 6.45 2 3 372 39.6 4.65 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 6.39 1 2 2 6 1.418E8 3.80 6.39 2 3 243.65 6.39 2 3 266 29.7 4.32 HVO_1228 halocyanin 6.33 1 4 4 10 1.095E8 10.37 6.33 4 5 706.51 6.33 4 5 821 83.7 4.17 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 6.25 1 0 3 12 6.886E8 6.60 6.25 3 6 558.06 6.25 3 6 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 6.25 1 0 3 12 6.886E8 6.60 6.25 3 6 558.06 6.25 3 6 400 44.1 5.14 HVO_2153 probable copper-containing oxidoreductase 6.23 1 2 2 4 3.768E7 3.22 6.23 2 2 226.06 6.23 2 2 385 42.1 5.82 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 6.16 1 3 3 12 1.718E8 4.17 6.16 3 6 577.49 6.16 3 6 438 46.4 4.58 HVO_2998 homoserine O-acetyltransferase 6.02 1 2 2 4 1.024E8 2.51 6.02 2 2 133.01 6.02 2 2 415 44.8 4.69 HVO_2058 NAD-dependent epimerase/dehydratase (homolog to dTDP-4-dehydrorhamnose reductase) 6.00 1 2 2 8 5.709E8 8.36 6.00 2 4 482.84 6.00 2 4 300 32.0 4.22 HVO_2911 deoxyribodipyrimidine photolyase 5.99 1 2 2 4 2.875E7 4.98 5.99 2 2 198.89 5.99 2 2 484 54.5 4.79 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 5.95 1 2 2 6 1.810E8 6.77 5.95 2 3 349.22 5.95 2 3 353 36.7 4.65 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 5.92 1 0 4 16 6.886E8 12.70 5.92 4 8 912.46 5.92 4 8 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 5.92 1 0 4 16 6.886E8 12.70 5.92 4 8 912.46 5.92 4 8 456 49.2 4.77 HVO_1047 NADPH:quinone reductase 5.88 1 2 2 2 2.712E7 147.40 5.88 2 2 323 33.8 4.27 HVO_1629 conserved hypothetical protein 5.84 1 3 3 10 8.558E7 4.81 5.84 3 5 322.17 5.84 3 5 531 56.3 4.69 HVO_1656 YyaL family protein 5.83 1 4 4 10 6.473E7 5.79 5.83 4 5 539.37 5.83 4 5 703 77.3 4.49 4504919 keratin 8 [Homo sapiens] 5.80 1 0 4 23 4.933E8 17.87 5.80 4 11 1343.89 5.80 4 12 483 53.7 5.59 HVO_0120 signal recognition particle receptor FtsY 5.70 1 2 2 2 1.966E7 150.15 5.70 2 2 456 48.2 4.17 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 5.69 1 2 2 4 2.735E7 2.62 5.69 2 2 145.62 5.69 2 2 492 52.1 4.83 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 5.67 1 2 2 6 5.834E7 4.29 5.67 2 3 253.95 5.67 2 3 388 41.9 4.35 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 5.59 1 2 2 3 3.352E8 235.88 5.59 2 3 376 41.8 4.91 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 5.54 1 7 7 13 9.797E7 6.27 4.19 6 6 671.92 5.54 7 7 1335 150.5 4.60 HVO_1925 probable GTP-binding protein 5.54 1 2 2 9 8.326E7 4.17 5.54 2 5 317.18 5.54 2 4 325 36.5 4.72 HVO_A0158 acyl-CoA synthetase 5.54 1 0 4 18 1.344E9 13.23 5.54 4 9 1144.70 5.54 4 9 650 71.2 4.63 HVO_A0328 2-keto-3-deoxygluconate kinase 5.35 1 1 2 8 3.757E8 0.00 5.35 2 4 309.55 5.35 2 4 318 34.0 4.60 HVO_0029 UvrABC system protein B 5.30 1 3 3 6 3.434E7 2.36 5.30 3 3 285.33 5.30 3 3 698 79.0 4.45 HVO_1424 conserved hypothetical protein 5.29 1 2 2 7 1.049E8 1.77 5.29 2 4 152.92 5.29 2 3 359 40.9 4.60 HVO_1199 acyl-CoA dehydrogenase 5.26 1 2 2 6 5.170E7 0.00 5.26 2 3 192.07 5.26 2 3 380 41.5 4.64 HVO_1585 acyl-CoA synthetase 5.24 1 4 4 10 1.243E8 6.68 5.24 4 5 439.56 5.24 4 5 668 74.1 4.48 31074633 keratin 6L [Homo sapiens] 5.23 1 0 3 12 7.810E8 10.45 5.23 3 6 904.82 5.23 3 6 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 5.23 1 0 3 12 7.810E8 10.45 5.23 3 6 904.82 5.23 3 6 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 5.23 1 0 3 12 7.810E8 10.45 5.23 3 6 904.82 5.23 3 6 535 57.7 7.20 HVO_2530 homolog to phosphoribosylamine--glycine ligase 5.23 1 2 2 5 5.034E7 1.91 5.23 2 2 207.45 5.23 2 3 440 49.8 4.70 HVO_0687 M20 family amidohydrolase 5.18 1 2 2 4 5.621E7 1.72 5.18 2 2 157.90 5.18 2 2 444 47.5 4.58 HVO_C0043 conserved hypothetical protein 5.14 1 3 3 11 1.023E8 3.76 5.14 3 6 635.41 3.78 2 5 661 73.8 4.75 HVO_1309 peptidase M24 family protein 5.12 1 2 2 14 1.315E8 8.54 5.12 2 7 614.14 5.12 2 7 391 42.1 4.36 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 5.04 1 2 2 2 5.284E7 3.76 5.04 2 2 337 35.9 4.39 HVO_C0057 Orc1-type DNA replication protein 5.02 1 2 2 4 4.166E7 0.00 5.02 2 2 80.90 5.02 2 2 418 46.3 5.02 HVO_2955 DEAD/DEAH box helicase 5.01 1 4 4 10 2.758E7 6.03 5.01 4 5 462.62 5.01 4 5 779 85.8 4.94 HVO_A0498 conserved hypothetical protein 5.01 1 2 2 6 9.427E7 1.72 5.01 2 3 359.95 5.01 2 3 379 42.7 4.55 HVO_2880 probable peptide chain release factor pelota 4.78 1 2 2 6 3.696E8 6.30 4.78 2 3 392.42 4.78 2 3 356 39.3 4.63 HVO_2888 homolog to elongator complex protein ELP3 4.73 1 3 3 7 7.744E7 2.07 4.73 3 4 193.58 3.27 2 3 550 62.6 5.01 HVO_0591 L-threonine-O-3-phosphate decarboxylase 4.71 1 2 2 2 3.231E7 1.64 4.71 2 2 340 36.0 4.54 HVO_A0257 Orc1-type DNA replication protein 4.71 1 2 2 10 3.725E7 9.55 4.71 2 5 629.64 4.71 2 5 425 48.0 4.94 HVO_2482 HD family hydrolase 4.68 1 0 2 6 1.616E7 1.94 4.68 2 3 356.16 4.68 2 3 406 44.7 4.89 HVO_C0074 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 4.64 1 3 3 9 5.306E7 3.06 4.64 3 5 264.06 3.19 2 4 690 75.9 4.79 109255249 keratin 4 [Homo sapiens] 4.55 1 0 3 11 4.512E8 6.25 4.55 3 5 562.58 4.55 3 6 594 63.9 8.25 HVO_B0100 aldehyde dehydrogenase 4.35 1 2 2 2 1.577E7 125.61 4.35 2 2 483 50.4 4.31 HVO_0744 homolog to carboxylate-amine ligase 4.34 1 2 2 3 3.519E8 257.07 4.34 2 3 369 41.7 4.88 HVO_0003 DNA-directed DNA polymerase D exonuclease subunit DP1 4.32 1 2 2 5 5.511E7 0.00 4.32 2 2 142.83 4.32 2 3 533 57.8 4.77 1181994 hair type I acidic keratin [Homo sapiens] 4.20 1 0 2 4 8.703E8 1.93 4.20 2 4 405 45.8 4.79 HVO_2311 glutamyl-tRNA reductase 4.12 1 2 2 6 3.035E7 1.90 4.12 2 3 200.05 4.12 2 3 461 49.2 4.54 HVO_A0064 Orc1-type DNA replication protein 3.81 1 1 3 6 4.571E7 3.61 3.81 3 3 298.96 3.81 3 3 499 55.5 4.91 3757666 HHa2 hair keratin type I intermediate filament [Homo sapiens] 3.79 1 0 2 4 8.703E8 1.93 3.79 2 4 448 50.3 4.87 15431312 type I hair keratin 2 [Homo sapiens] 3.79 1 0 2 4 8.703E8 1.93 3.79 2 4 448 50.3 4.84 HVO_2380 AAA-type ATPase (CDC48 subfamily) 3.77 1 3 3 8 6.813E7 2.85 3.77 3 4 314.59 3.77 3 4 743 81.9 4.82 18031720 keratin protein K6irs [Homo sapiens] 3.73 1 0 2 10 5.593E8 8.29 3.73 2 5 637.70 3.73 2 5 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 3.72 1 0 2 10 5.593E8 8.29 3.72 2 5 637.70 3.72 2 5 511 55.8 6.89 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 10 5.593E8 8.29 3.63 2 5 637.70 3.63 2 5 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.59 1 0 2 10 5.593E8 8.29 3.59 2 5 637.70 3.59 2 5 529 57.8 7.71 28173564 keratin 6 irs3 [Homo sapiens] 3.52 1 0 2 10 5.593E8 8.29 3.52 2 5 637.70 3.52 2 5 540 58.9 7.23 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 10 1.183E9 3.81 3.45 2 5 583.32 3.45 2 5 464 50.6 5.47 HVO_B0149 oleate hydratase 3.38 1 1 2 4 3.958E8 2.18 3.38 2 2 205.72 3.38 2 2 533 60.1 4.64 31074631 keratin 1b [Homo sapiens] 3.29 1 0 2 8 1.576E9 7.68 3.29 2 4 582.30 3.29 2 4 578 61.8 5.97 HVO_A0254 DUF234 domain protein 3.25 1 2 2 8 7.928E7 2.02 3.25 2 4 297.78 3.25 2 4 461 52.7 4.78 HVO_1456 receiver/sensor box histidine kinase 2.77 1 1 2 4 6.018E7 0.00 2.77 2 2 91.18 2.77 2 2 506 53.8 4.70 4504911 keratin 13 isoform b [Homo sapiens] 2.62 1 0 2 8 1.022E8 8.39 2.62 2 4 529.45 2.62 2 4 420 45.8 4.88 HVO_B0265 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 2.48 1 2 2 2 9.011E8 0.00 2.48 2 2 1048 112.5 4.61 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 2.40 1 0 2 8 1.022E8 8.39 2.40 2 4 529.45 2.40 2 4 458 49.6 4.96 HVO_2736 tRNA(Met) cytidine acetyltransferase 2.39 1 2 2 6 1.621E8 3.83 2.39 2 3 222.91 2.39 2 3 754 81.2 4.96