Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0356 translation elongation factor aEF-2 81.43 1 49 49 718 5.952E9 696.60 80.61 48 359 44870.44 77.72 48 359 727 80.4 4.73 HVO_0359 translation elongation factor aEF-1 alpha subunit 80.52 1 22 26 803 1.629E10 774.72 74.35 24 378 58187.14 79.33 25 425 421 45.7 4.73 HVO_0880 conserved hypothetical protein 75.24 1 27 27 355 1.314E9 296.19 72.64 26 174 20984.60 75.24 27 181 307 36.3 4.74 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 72.29 1 18 18 223 2.778E9 199.09 72.29 18 111 14358.17 72.29 18 112 350 37.6 4.54 HVO_1921 serine--tRNA ligase 70.43 1 29 29 143 6.835E8 130.99 70.43 28 71 8964.01 69.13 28 72 460 52.0 4.46 HVO_0055 CBS domain protein 70.42 1 13 13 72 7.018E8 83.38 70.42 13 35 6187.51 70.42 13 37 284 30.8 4.27 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 68.68 1 15 15 73 5.178E8 75.98 68.68 15 35 5515.08 68.68 15 38 281 30.6 4.59 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 68.24 1 0 6 28 5.714E8 24.12 68.24 6 14 1808.57 54.12 5 14 85 10.0 5.94 HVO_0329 branched-chain amino acid aminotransferase 67.95 1 16 16 85 6.560E8 76.96 67.95 16 42 5293.23 67.95 16 43 312 35.0 4.58 HVO_2862 serine hydroxymethyltransferase 67.23 1 17 17 206 2.696E9 188.68 67.23 17 102 13232.30 67.23 17 104 415 44.3 4.53 HVO_0104 DNA repair and recombination protein RadA 66.47 1 17 17 124 9.076E8 95.94 61.22 16 60 8332.02 66.47 17 64 343 37.3 4.64 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 64.74 1 13 13 171 2.404E9 160.96 64.74 13 87 10540.62 64.74 13 84 312 34.5 4.98 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 64.30 1 16 16 126 2.412E9 93.17 64.30 16 63 6828.69 64.30 16 63 381 41.0 4.23 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 63.99 1 12 12 53 2.307E8 54.81 63.99 12 26 3321.03 63.99 12 27 286 31.2 4.54 HVO_2969 threonine synthase 63.96 1 20 20 99 1.027E9 93.52 63.96 20 50 6937.24 51.79 18 49 419 44.4 4.49 HVO_0348 DNA-directed RNA polymerase subunit B' 63.22 1 31 31 177 7.847E8 158.09 63.22 31 86 10529.46 61.74 30 91 609 67.7 4.92 HVO_0602 3-dehydroquinate dehydratase 63.16 1 12 12 39 9.554E7 29.44 63.16 12 19 2075.34 59.51 11 20 247 27.3 4.51 HVO_2900 fumarate hydratase 63.11 1 18 18 114 1.043E9 126.83 63.11 18 58 8146.84 63.11 18 56 469 50.1 4.78 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 62.82 1 14 14 70 4.581E8 57.14 62.82 14 35 4570.17 62.82 14 35 355 38.2 4.68 HVO_0677 aspartate--tRNA ligase 62.44 1 20 20 242 2.732E9 233.33 62.44 20 125 15698.10 62.44 20 117 434 48.7 4.50 HVO_2413 translation elongation factor aEF-1 alpha subunit 61.90 1 15 19 148 3.685E9 106.72 60.00 18 71 8170.89 61.90 18 77 420 45.6 4.75 HVO_1454 aspartate carbamoyltransferase catalytic subunit 61.84 1 13 13 42 1.041E8 42.73 61.84 13 22 2861.19 52.96 12 20 304 33.7 4.92 HVO_0850 proteasome-activating nucleotidase 61.23 1 16 17 99 4.702E8 112.46 56.05 16 49 7353.20 61.23 17 50 405 45.6 4.60 HVO_0400 conserved hypothetical protein 61.11 1 5 5 9 4.649E7 8.95 56.35 4 4 482.12 61.11 5 5 126 13.9 4.68 HVO_0347 DNA-directed RNA polymerase subunit B'' 60.84 1 31 31 182 6.942E8 152.29 57.77 29 91 11018.02 60.84 31 91 521 58.9 5.00 HVO_0161 ATP phosphoribosyltransferase 60.50 1 13 13 58 2.829E8 51.76 57.30 12 28 4107.72 60.50 13 30 281 30.4 4.60 HVO_0239 glutamine synthetase 60.31 1 21 21 136 2.164E9 131.94 57.24 20 67 9356.04 60.31 21 69 456 50.5 4.56 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 60.00 1 16 16 67 2.216E8 61.59 60.00 16 33 4250.52 60.00 16 34 340 38.8 4.58 HVO_2724 beta-lactamase domain protein 60.00 1 19 19 142 1.361E9 134.23 60.00 19 71 8010.45 60.00 19 71 450 50.1 5.40 HVO_0581 "cell division protein FtsZ, type II" 59.75 1 16 16 90 4.660E8 101.00 59.75 16 46 6281.82 59.75 16 44 400 42.5 4.75 HVO_2783 30S ribosomal protein S4 59.43 1 11 11 52 6.190E8 53.19 59.43 11 26 3396.69 59.43 11 26 175 20.1 5.24 HVO_0024 thiosulfate sulfurtransferase 59.30 1 10 10 41 2.981E8 39.49 54.65 9 20 2558.59 57.36 9 21 258 28.4 4.30 HVO_0433 F420H2:NADP oxidoreductase 59.01 1 9 9 32 2.727E8 35.95 59.01 9 16 2532.93 59.01 9 16 222 23.3 4.72 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 58.92 1 13 13 64 6.427E8 37.14 54.21 12 31 3856.31 58.92 13 33 297 31.3 4.36 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 58.69 1 15 15 71 8.579E8 60.64 53.77 14 33 4592.86 58.69 15 38 305 33.8 4.74 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 58.59 1 16 16 138 1.533E9 165.17 58.59 16 69 10481.87 58.59 16 69 384 41.4 4.41 HVO_0025 thiosulfate sulfurtransferase 58.39 1 9 10 132 3.271E9 126.36 58.39 10 66 8779.77 58.39 10 66 286 32.1 4.28 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 58.35 1 16 16 86 1.379E9 76.33 54.24 14 41 5422.27 58.35 16 45 413 45.8 4.45 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 57.14 1 6 6 27 1.189E8 16.64 50.26 5 13 1445.68 57.14 6 14 189 21.7 4.46 HVO_1273 inosine-5'-monophosphate dehydrogenase 56.43 1 19 19 173 9.649E8 172.41 53.82 18 85 11615.68 56.43 19 88 498 53.3 4.55 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 56.25 1 26 26 141 1.070E9 119.13 53.38 24 71 8520.42 54.56 25 70 592 66.6 4.61 HVO_0859 FeS assembly ATPase SufC 56.15 1 16 16 106 1.221E9 77.57 54.15 15 52 6439.30 56.15 16 54 301 33.4 4.35 HVO_1507 acetolactate synthase small subunit 55.96 1 9 9 33 1.107E8 26.17 50.46 8 16 2120.81 55.96 9 17 218 23.7 4.94 HVO_2015 conserved hypothetical protein 55.94 1 12 12 162 4.716E9 179.02 55.94 12 81 12602.90 55.94 12 81 345 37.7 4.25 HVO_0829 peptidase S9 family protein 55.92 1 19 19 71 1.877E8 50.80 55.92 19 36 3313.11 55.92 19 35 608 67.4 4.54 HVO_2384 CBS domain protein 55.79 1 18 19 112 9.206E8 70.88 54.21 18 57 5964.83 55.79 19 55 380 42.5 5.01 HVO_1133 conserved hypothetical protein 55.45 1 4 4 15 8.078E7 10.21 55.45 4 7 898.91 55.45 4 8 101 11.7 4.58 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 55.45 1 13 13 48 1.344E8 45.79 55.45 13 24 2907.47 55.45 13 24 422 43.6 4.72 HVO_0869 glutamate synthase large subunit 55.39 1 68 69 425 1.270E9 394.83 55.00 67 213 27894.97 55.39 69 212 1511 163.8 4.70 HVO_2889 RecJ domain protein 55.28 1 31 31 175 1.366E9 183.61 55.28 31 89 12075.57 54.32 30 86 729 79.1 4.37 HVO_0455 thermosome subunit 2 54.94 1 26 27 156 8.257E8 164.31 54.94 27 76 10790.62 54.94 27 80 557 59.3 4.37 HVO_0792 3-dehydroquinate synthase type II 54.34 1 16 16 63 3.976E8 76.19 49.23 15 31 4626.05 54.34 14 32 392 43.1 4.44 HVO_1649 methionine adenosyltransferase 54.23 1 15 15 55 2.406E8 42.96 54.23 15 28 3142.42 54.23 15 27 402 43.5 4.45 HVO_1684 threonine--tRNA ligase 53.97 1 30 30 153 8.732E8 134.44 53.97 30 78 9276.65 53.97 30 75 643 73.4 4.45 HVO_2059 NAD-dependent epimerase/dehydratase 53.55 1 12 12 52 3.607E8 36.76 53.55 11 26 3020.55 53.55 12 26 310 34.1 4.40 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 53.54 1 8 8 38 3.015E8 37.20 53.54 8 18 2618.10 53.54 8 20 254 26.9 4.42 HVO_2552 30S ribosomal protein S4e 53.44 1 10 10 104 2.876E9 99.80 53.44 10 51 6267.06 53.44 10 53 247 26.6 4.58 HVO_2519 conserved hypothetical protein 53.40 1 13 13 75 3.891E8 76.35 48.69 12 36 6235.97 53.40 13 39 382 40.7 4.35 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 53.35 1 13 13 63 3.003E8 66.26 53.35 13 31 5402.59 53.35 13 32 343 38.4 4.94 HVO_0661 dCTP deaminase (dUMP-forming) 53.33 1 7 7 23 9.605E7 15.78 47.69 6 11 1141.10 46.15 6 12 195 21.2 4.59 HVO_2013 "FtsZ family protein, type III" 53.30 1 11 11 56 4.024E8 80.44 47.46 10 27 4851.95 53.30 11 29 394 41.5 4.61 HVO_0167 adenosylhomocysteinase 53.27 1 15 15 80 3.565E8 73.86 49.07 14 40 5226.50 53.27 15 40 428 46.6 4.39 HVO_2700 AAA-type ATPase (CDC48 subfamily) 52.92 1 35 36 146 2.137E8 121.17 51.33 35 72 7890.62 52.92 36 74 754 82.8 4.75 HVO_2191 formyltetrahydrofolate deformylase 52.91 1 14 14 53 4.233E8 41.04 52.91 14 28 3221.92 52.91 14 25 327 36.2 4.63 HVO_0870 proline--tRNA ligase 52.87 1 16 16 74 5.462E8 54.60 50.41 15 37 4534.23 47.54 15 37 488 54.9 4.44 HVO_1332 conserved hypothetical protein 52.71 1 6 6 18 1.468E8 12.17 44.19 5 8 1249.66 52.71 6 10 129 14.9 4.16 HVO_0240 Lrp/AsnC family transcription regulator 52.63 1 6 7 21 2.940E8 13.15 47.37 6 10 1271.37 52.63 7 11 152 16.9 4.39 HVO_0133 thermosome subunit 1 52.50 1 18 20 139 1.165E9 131.34 48.93 19 70 10008.67 52.50 20 69 560 58.9 4.25 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 52.42 1 21 21 76 1.766E8 87.66 52.42 21 38 5887.07 52.42 21 38 599 65.3 4.51 HVO_1145 30S ribosomal protein S1e 52.27 1 11 11 42 3.280E8 45.46 52.27 11 21 2921.30 52.27 11 21 220 24.8 4.86 HVO_2588 isocitrate dehydrogenase (NADP) 52.27 1 20 20 156 2.309E9 155.23 49.16 19 76 11018.19 52.27 20 80 419 45.8 4.59 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 52.24 1 23 23 111 6.023E8 104.36 52.24 23 55 7374.41 47.92 22 56 624 67.6 4.27 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 51.95 1 8 8 27 1.069E8 23.86 48.48 7 13 1801.37 51.95 8 14 231 25.0 4.25 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 51.57 1 12 12 114 1.275E9 103.99 51.57 12 57 7696.06 51.57 12 57 287 31.0 4.73 HVO_0449 prephenate dehydratase 51.12 1 10 10 33 3.133E8 37.50 51.12 10 17 2403.39 44.40 9 16 268 28.7 4.64 HVO_0203 replication factor C small subunit 51.07 1 14 14 64 1.901E8 54.30 51.07 14 32 4117.69 51.07 14 32 327 36.2 4.51 HVO_1973 conserved hypothetical protein 50.90 1 5 5 16 1.009E8 18.62 41.92 4 7 1644.86 50.90 5 9 167 18.1 4.36 HVO_1132 adenylosuccinate synthase 50.79 1 23 23 152 1.299E9 125.16 47.63 22 75 9870.33 50.34 21 77 443 48.2 4.56 HVO_2621 phosphoenolpyruvate carboxylase 50.72 1 36 36 223 1.017E9 191.11 50.72 36 109 14218.93 50.72 36 114 897 102.3 4.64 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 50.71 1 23 23 285 4.464E9 276.08 48.81 21 142 19258.64 50.71 23 143 631 68.4 4.49 HVO_0388 homolog to ribonuclease R 50.57 1 18 18 86 3.556E8 91.00 44.87 17 41 6128.24 50.57 18 45 439 50.3 4.73 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 50.55 1 14 14 67 3.254E8 66.87 50.55 14 34 4342.58 50.55 14 33 457 48.4 4.35 HVO_0046 putative glutamate--argW ligase 50.52 1 11 11 56 2.898E8 51.16 50.52 11 27 4064.66 50.52 11 29 291 31.9 4.87 HVO_1189 aldehyde dehydrogenase 50.39 1 17 17 76 4.705E8 78.40 43.11 16 37 5236.98 50.39 17 39 508 56.1 4.59 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 50.32 1 13 26 107 6.310E8 108.94 50.32 26 53 7120.88 47.78 25 54 473 51.2 5.05 HVO_2968 phosphoglycerate dehydrogenase 50.10 1 18 18 169 1.686E9 224.19 50.10 18 85 14465.83 50.10 18 84 525 55.3 4.36 HVO_0212 homolog to lactoylglutathione lyase 50.00 1 4 4 12 1.532E8 12.94 50.00 4 6 820.27 50.00 4 6 124 13.5 4.13 HVO_2756 50S ribosomal protein L10 50.00 1 10 10 50 3.815E8 27.83 41.09 9 24 2815.81 50.00 10 26 348 36.9 3.99 HVO_0393 UvrABC system protein A 49.95 1 37 37 119 1.346E8 106.45 49.95 37 61 7336.99 49.34 36 58 983 108.6 4.82 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 49.70 1 16 16 59 1.855E8 41.45 45.24 15 29 3199.00 49.70 16 30 336 38.0 4.61 HVO_1690 DHH family phosphoesterase 49.69 1 13 13 45 1.210E8 42.49 49.69 13 22 3222.52 49.69 13 23 485 52.1 4.48 HVO_2419 hydroxymethylglutaryl-CoA synthase 49.66 1 18 18 69 3.897E8 46.88 49.66 18 34 3290.02 49.66 18 35 445 50.1 4.64 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 49.44 1 14 14 70 3.261E8 73.44 49.44 14 35 4579.83 49.44 14 35 445 47.8 4.86 HVO_0729 inorganic pyrophosphatase 49.15 1 8 8 48 6.497E8 45.82 49.15 8 25 2748.61 49.15 8 23 177 20.4 4.16 HVO_0415 repair helicase 49.03 1 22 22 97 4.111E8 83.20 49.03 22 49 6533.21 49.03 22 48 616 69.6 4.70 HVO_2624 CTP synthase 49.00 1 19 19 109 5.806E8 90.99 46.81 17 53 7007.43 49.00 19 56 549 60.8 4.70 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 48.95 1 17 17 67 2.877E8 63.95 47.68 16 33 4293.76 48.95 17 34 474 53.4 4.59 HVO_0175 DNA polymerase sliding clamp 48.58 1 8 8 69 1.115E9 55.54 48.58 8 35 4586.86 48.58 8 34 247 26.7 4.39 HVO_1338 replication protein A 48.48 1 14 14 51 1.846E8 41.22 46.84 13 26 2712.51 44.50 13 25 427 46.0 4.36 HVO_1284 GTP cyclohydrolase III 48.28 1 9 9 32 1.535E8 26.46 39.46 8 15 1759.11 48.28 9 17 261 28.9 4.70 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 48.26 1 10 10 48 4.492E8 53.01 48.26 10 24 4102.51 48.26 10 24 259 28.0 4.50 HVO_0806 pyruvate kinase 48.21 1 20 20 122 1.031E9 125.55 43.76 19 60 8421.54 48.21 20 62 585 62.0 4.54 HVO_2544 30S ribosomal protein S5 47.66 1 9 9 59 1.208E9 48.54 47.66 9 29 3122.71 47.66 9 30 214 23.3 9.29 HVO_0874 beta-lactamase domain protein 47.50 1 24 24 151 7.773E8 132.69 47.50 24 77 10946.30 41.88 23 74 640 71.9 5.14 HVO_1541 glycerol kinase 47.25 1 19 19 125 1.579E9 96.80 43.92 18 62 8049.16 46.86 18 63 510 56.7 4.50 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 47.24 1 10 10 30 1.847E8 31.83 43.92 8 14 2115.39 47.24 10 16 362 39.6 4.82 HVO_1082 homolog to orotate phosphoribosyltransferase 47.14 1 8 9 27 1.687E8 20.13 47.14 9 14 1547.91 43.81 8 13 210 22.3 4.42 HVO_2487 aspartate-semialdehyde dehydrogenase 47.09 1 9 9 75 1.269E9 61.42 47.09 9 40 4360.12 47.09 9 35 344 36.6 4.41 HVO_0424 ABC-type transport system ATP-binding protein 47.02 1 21 21 81 2.268E8 68.38 45.03 20 39 4612.21 47.02 21 42 604 67.2 4.49 HVO_1091 proteasome alpha subunit 46.83 1 11 12 49 4.081E8 49.82 46.83 12 25 3164.21 46.83 12 24 252 27.6 4.56 HVO_0519 replication protein A 46.79 1 19 19 122 2.349E8 66.49 46.79 19 62 6484.61 46.79 19 60 483 51.0 4.13 HVO_2558 30S ribosomal protein S3 46.71 1 12 12 101 2.181E9 105.77 42.43 11 48 7988.52 44.08 11 53 304 33.4 4.06 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 46.39 1 16 16 58 3.214E8 49.78 46.39 16 30 3451.11 45.25 15 28 526 57.2 4.31 HVO_0317 A-type ATP synthase subunit B 46.37 1 14 14 103 1.312E9 115.72 46.37 14 51 8015.82 46.37 14 52 468 51.9 4.25 HVO_0778 thermosome subunit 3 46.37 1 16 18 101 6.754E8 118.66 46.37 18 49 8356.00 46.37 18 52 524 55.2 4.59 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 89 1.129E9 107.90 43.25 7 43 8330.61 46.37 8 46 289 29.8 4.27 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 46.33 1 19 19 71 3.309E8 65.39 46.33 19 35 4934.19 46.33 19 36 626 67.6 4.65 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 46.24 1 10 10 43 8.255E8 47.11 42.11 9 21 3116.99 42.48 9 22 266 27.8 4.84 HVO_A0207 CRISPR-associated protein Cas7 46.18 1 9 9 44 4.374E8 53.81 46.18 9 23 3315.57 46.18 9 21 340 38.2 4.54 HVO_0480 phosphoglycerate kinase 46.13 1 16 16 85 5.901E8 103.24 46.13 16 42 7272.53 46.13 16 43 401 43.6 4.37 HVO_1571 DNA topoisomerase VI subunit B 46.12 1 25 26 105 2.553E8 91.47 40.98 23 51 6341.93 46.12 26 54 798 87.4 4.73 HVO_0809 methionine--tRNA ligase 46.08 1 24 24 124 5.040E8 126.64 46.08 24 62 8898.68 46.08 24 62 740 81.9 4.37 HVO_2204 "FtsZ family protein, type III" 46.08 1 12 15 81 8.722E8 92.38 46.08 15 40 6465.25 46.08 15 41 395 42.0 4.68 HVO_2675 histidinol dehydrogenase 46.03 1 14 14 44 2.312E8 39.02 39.02 13 22 2769.87 44.63 13 22 428 45.4 4.50 HVO_1134 conserved hypothetical protein 45.97 1 25 25 99 2.183E8 83.13 45.97 24 49 6222.19 45.97 25 50 757 80.6 4.35 HVO_2435 peptidase M24 family protein 45.92 1 10 10 40 1.341E8 34.57 45.92 10 20 2536.15 45.92 10 20 368 40.0 4.53 HVO_3007 malate dehydrogenase 45.72 1 13 13 157 1.966E9 132.25 45.72 13 81 8585.74 45.72 13 76 304 32.6 4.40 HVO_2188 phosphoribosylformylglycinamidine synthase 1 45.54 1 9 9 30 3.097E8 30.47 40.63 8 15 2198.60 45.54 8 15 224 23.9 4.36 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 45.43 1 24 25 131 6.624E8 139.65 43.82 23 64 8994.97 45.43 25 67 623 62.1 5.30 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 45.39 1 22 22 187 1.943E9 170.34 45.39 22 93 12447.69 45.39 21 94 586 64.0 4.49 HVO_1546 dihydroxyacetone kinase subunit DhaK 45.18 1 12 12 86 7.825E8 64.47 37.05 11 44 4399.20 45.18 12 42 332 34.8 4.22 HVO_2981 uracil phosphoribosyltransferase 45.13 1 9 9 40 3.604E8 36.68 37.61 8 17 3292.45 45.13 9 23 226 24.5 4.49 HVO_B0061 precorrin-2 C20-methyltransferase 45.11 1 8 8 30 1.014E8 17.24 45.11 8 15 1606.58 45.11 8 15 235 25.3 4.63 HVO_0999 DRTGG domain protein 44.97 1 12 12 60 2.887E8 70.69 44.97 12 30 4858.75 44.97 12 30 378 39.8 4.44 HVO_1572 DNA gyrase subunit B 44.91 1 23 23 88 2.594E8 72.15 44.91 23 45 5497.36 44.91 23 43 639 71.2 4.83 HVO_1545 dihydroxyacetone kinase subunit DhaL 44.83 1 8 9 44 3.121E8 36.91 41.81 8 21 2507.11 44.83 9 23 232 24.8 4.48 HVO_0743 probable phosphodiesterase 44.77 1 23 23 114 5.719E8 88.91 44.77 23 57 6468.20 39.20 21 57 449 50.5 4.56 HVO_1637 FKBP-type peptidylprolyl isomerase 44.77 1 11 12 87 1.907E9 91.62 34.64 10 41 7081.35 44.77 12 46 306 33.8 3.76 HVO_1080 conserved hypothetical protein 44.68 1 7 7 22 1.580E8 8.97 44.68 7 12 973.88 27.13 6 10 188 21.1 4.31 HVO_1590 DnaK-type molecular chaperone Hsp70 44.64 1 22 22 154 1.282E9 151.92 44.64 22 78 11148.71 39.68 21 76 625 67.2 4.18 HVO_2549 30S ribosomal protein S8 44.62 1 5 5 26 3.210E8 28.71 44.62 5 13 1789.03 44.62 5 13 130 14.1 4.79 HVO_0717 "cell division protein FtsZ, type I" 44.59 1 14 14 84 9.206E8 80.44 44.59 14 42 5722.40 44.59 14 42 379 39.8 4.40 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 44.56 1 20 20 98 5.334E8 76.07 44.56 20 49 6031.16 44.56 20 49 496 55.0 4.53 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 44.53 1 0 19 102 4.615E8 96.37 44.53 19 51 6636.95 44.53 19 51 384 42.4 5.40 HVO_1824 conserved hypothetical protein 44.52 1 13 13 49 1.754E8 60.43 44.52 13 24 3794.05 44.52 13 25 429 47.4 4.20 HVO_A0205 CRISPR-associated endoribonuclease Cas6 44.49 1 11 11 45 2.340E8 47.70 44.49 11 22 3378.86 44.49 11 23 272 31.0 5.44 HVO_0417 metal-dependent carboxypeptidase 44.42 1 16 16 57 2.079E8 34.12 41.04 15 28 3319.24 43.03 15 29 502 57.3 4.42 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 44.34 1 40 40 228 7.584E8 191.88 42.79 37 113 14463.64 43.76 39 115 1033 114.3 4.45 HVO_A0636 YbaK domain protein 44.30 1 4 4 16 1.017E8 21.95 44.30 4 8 1574.21 44.30 4 8 158 16.7 4.54 HVO_0206 alanine--tRNA ligase 44.25 1 31 31 172 3.102E8 143.75 43.38 30 85 11011.77 44.25 31 87 922 102.4 4.54 HVO_2040 NAD-dependent epimerase/dehydratase 44.12 1 6 11 56 5.836E8 48.36 44.12 11 28 3586.00 44.12 11 28 306 33.8 4.51 HVO_0789 tryptophan synthase alpha subunit 44.04 1 7 7 27 1.585E8 28.50 44.04 7 14 1737.06 44.04 7 13 277 29.6 4.21 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 44.02 1 6 6 26 2.024E8 31.97 44.02 6 13 2151.18 44.02 6 13 184 19.8 5.30 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 44.00 1 16 16 90 6.730E8 85.06 42.10 15 43 6228.34 44.00 16 47 525 56.4 4.40 HVO_B0059 cobalt-precorrin 5A hydrolase 43.87 1 11 11 50 1.850E8 52.61 43.87 11 25 3111.93 43.87 11 25 326 34.5 4.51 HVO_0353 30S ribosomal protein S12 43.66 1 9 9 47 4.543E8 48.75 43.66 9 24 2606.67 39.44 8 23 142 15.5 9.91 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 43.45 1 8 8 43 2.832E8 53.65 38.10 7 21 3820.11 43.45 8 22 336 36.8 4.12 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 43.43 1 7 22 83 6.310E8 68.75 43.43 21 41 4991.24 40.89 21 42 472 51.6 5.16 HVO_0118 50S ribosomal protein L20e 43.10 1 2 2 3 2.115E7 4.91 43.10 2 3 58 6.4 6.52 HVO_2961 dihydrolipoyl dehydrogenase 42.95 1 13 13 49 1.662E8 53.42 37.47 12 23 3585.18 42.95 13 26 475 49.9 4.41 HVO_1506 ketol-acid reductoisomerase 42.82 1 9 9 46 4.409E8 36.90 42.82 9 23 2822.36 42.82 9 23 348 37.9 4.34 HVO_A0206 CRISPR-associated protein Cas8b 42.82 1 22 22 92 2.966E8 78.87 42.82 22 46 5768.41 42.82 22 46 717 79.3 4.60 HVO_0316 A-type ATP synthase subunit A 42.66 1 20 20 129 9.624E8 130.23 42.66 20 65 9148.68 42.66 20 64 586 64.5 4.25 HVO_1212 KaiC-type circadian regulator CirA 42.28 1 10 10 50 6.533E8 53.84 42.28 10 25 3791.49 42.28 10 25 246 27.5 4.45 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 42.25 1 15 15 70 2.956E8 71.43 38.85 14 35 4556.76 42.25 15 35 471 51.0 4.48 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 42.08 1 7 7 22 4.386E7 14.41 42.08 7 11 1160.43 42.08 7 11 202 22.2 5.11 HVO_0861 SufB domain protein 42.04 1 13 13 78 1.006E9 79.33 42.04 13 41 6221.55 36.82 12 37 402 44.7 4.23 HVO_2454 anthranilate synthase component I 41.98 1 17 17 67 1.625E8 72.52 41.98 17 33 4727.32 41.98 17 34 524 55.9 4.56 HVO_1504 3-isopropylmalate dehydratase large subunit 41.86 1 16 17 112 1.291E9 126.39 41.86 17 56 8323.14 41.86 17 56 473 51.6 4.55 HVO_0860 SufB domain protein 41.81 1 16 16 137 1.132E9 114.68 40.13 15 65 8752.82 41.81 16 72 476 53.2 4.69 HVO_B0118 SMC-like protein Sph2 41.77 1 26 27 98 5.822E8 89.18 39.29 25 48 5674.30 40.99 26 50 644 73.8 4.41 HVO_2057 sugar nucleotidyltransferase 41.74 1 12 12 65 5.689E8 71.48 41.74 12 33 4866.78 41.74 12 32 357 37.8 4.44 17318569 keratin 1 [Homo sapiens] 41.61 1 1 29 220 1.211E9 230.40 41.61 29 110 15859.43 41.61 29 110 644 66.0 8.12 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 41.59 1 9 9 41 4.484E8 30.99 32.74 7 19 2550.14 41.59 9 22 226 25.5 4.25 HVO_0324 arginine--tRNA ligase 41.57 1 20 20 88 4.845E8 97.91 40.20 19 44 6351.58 40.55 19 44 587 65.0 4.35 HVO_0350 DNA-directed RNA polymerase subunit A'' 41.53 1 17 17 72 8.705E8 69.33 35.08 15 36 4601.63 40.33 16 36 419 46.1 4.35 HVO_1031 thioredoxin-disulfide reductase 41.52 1 10 10 43 1.856E8 38.38 41.52 10 22 2766.83 41.52 10 21 342 37.4 4.46 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 41.31 1 12 12 79 7.128E8 52.93 37.45 11 38 4842.22 41.31 12 41 259 29.9 4.36 HVO_0349 DNA-directed RNA polymerase subunit A' 41.19 1 32 32 178 5.231E8 171.69 40.57 31 89 13003.61 41.09 31 89 976 108.8 4.81 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 41.19 1 12 12 43 1.537E8 46.39 41.19 12 22 2675.36 41.19 12 21 454 48.5 4.46 HVO_1967 glucose-6-phosphate isomerase 41.16 1 12 12 44 1.870E8 34.90 41.16 12 22 3011.12 41.16 12 22 430 45.6 4.40 HVO_2336 pyridoxal biosynthesis lyase PdxS 41.06 1 13 13 59 3.078E8 58.19 37.42 11 26 4296.16 34.11 12 33 302 32.5 4.81 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 40.77 1 10 10 53 1.442E8 43.79 40.77 10 27 3173.07 40.77 10 26 363 39.3 4.97 HVO_2646 dihydroxy-acid dehydratase 40.75 1 17 17 115 8.614E8 115.73 40.75 17 58 7971.97 40.75 17 57 584 61.8 4.42 HVO_1300 triosephosphate isomerase 40.65 1 5 5 37 6.445E8 36.10 40.65 5 19 2494.33 40.65 5 18 214 21.3 4.26 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 40.56 1 9 9 44 3.505E8 44.36 40.56 9 21 3111.08 40.56 9 23 360 39.6 4.39 HVO_2130 IclR family transcription regulator 40.44 1 10 10 32 5.846E7 17.52 36.40 9 14 1945.64 40.44 10 18 272 30.1 5.55 HVO_1306 chorismate synthase 40.26 1 12 12 72 2.620E8 91.95 40.26 12 36 5016.20 40.26 12 36 385 41.9 4.83 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 28 1.438E8 31.46 40.26 5 14 2024.43 40.26 5 14 154 17.5 4.50 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 40.22 1 0 28 214 1.211E9 223.85 40.22 28 107 15518.26 40.22 28 107 644 66.0 8.12 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 40.21 1 5 5 16 1.060E8 9.50 40.21 5 8 886.42 40.21 5 8 97 10.8 4.53 HVO_0541 aconitate hydratase 40.19 1 25 25 96 3.061E8 50.86 36.78 22 48 5191.73 40.19 25 48 938 102.1 4.40 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 40.17 1 22 22 80 1.919E8 66.07 38.00 21 39 5084.53 40.17 21 41 600 65.3 4.68 HVO_2774 enolase 40.10 1 11 11 55 6.805E8 43.06 40.10 11 26 3489.47 40.10 11 29 399 42.0 4.37 HVO_0314 A-type ATP synthase subunit C 39.94 1 12 12 46 2.195E8 32.02 35.92 11 21 2854.21 39.94 12 25 348 38.7 4.50 HVO_2225 AstE family protein 39.88 1 7 7 34 3.247E8 38.34 39.88 7 18 2338.82 39.88 7 16 341 36.9 4.53 HVO_1502 3-isopropylmalate dehydrogenase 39.81 1 10 10 66 7.253E8 70.10 39.81 10 32 5114.89 39.81 10 34 324 33.7 4.23 HVO_1955 aconitate hydratase 39.60 1 22 22 200 2.767E9 203.14 39.60 22 98 14190.38 39.60 22 102 654 70.4 4.45 HVO_A0331 D-galactonate dehydratase 39.32 1 8 8 25 6.340E7 21.38 39.32 8 12 1561.74 39.32 8 13 384 42.8 4.83 HVO_2861 conserved hypothetical protein 39.27 1 9 9 35 2.766E8 31.83 39.27 9 18 2104.43 39.27 8 17 275 29.1 4.27 HVO_0292 replication protein A 39.23 1 9 9 31 1.204E8 41.64 39.23 9 16 2564.86 36.33 8 15 311 34.6 4.31 HVO_1018 RecJ domain protein 39.18 1 23 23 121 5.785E8 93.02 37.28 22 60 8048.27 39.18 23 61 633 69.8 4.58 HVO_1901 translation initiation factor aIF-2 gamma subunit 39.17 1 12 12 69 6.402E8 42.33 39.17 12 34 3815.87 39.17 12 35 411 43.9 4.36 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 38.93 1 9 9 47 8.290E8 41.50 38.93 9 24 3121.74 37.14 8 23 280 30.1 4.44 HVO_0109 cysteine desulfurase 38.73 1 12 12 45 1.552E8 39.86 38.73 12 22 2597.46 38.73 12 23 426 46.8 4.56 HVO_0313 A-type ATP synthase subunit E 38.66 1 5 5 25 1.033E8 34.30 31.44 4 13 1893.10 33.51 4 12 194 22.0 4.31 HVO_A0388 Lrp/AsnC family transcription regulator 38.51 1 5 5 15 3.499E7 6.75 38.51 5 8 690.43 38.51 5 7 174 20.1 4.86 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 38.49 1 8 8 32 6.030E7 36.20 38.49 8 16 2492.69 38.49 8 16 265 29.3 4.92 HVO_2726 glutamate--tRNA ligase 38.46 1 19 19 71 2.484E8 42.70 38.46 19 36 3850.29 34.53 18 35 585 65.2 4.58 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 38.22 1 12 12 59 3.276E8 60.25 38.22 12 30 3552.89 38.22 12 29 348 38.2 4.32 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 38.19 1 12 12 45 2.472E8 43.01 38.19 12 23 2824.70 36.20 11 22 453 47.5 4.63 HVO_0980 NADH dehydrogenase-like complex subunit CD 38.06 1 13 17 57 1.642E8 43.94 36.98 15 28 3208.51 33.03 16 29 557 63.4 4.53 HVO_1854 histidine--tRNA ligase 38.05 1 14 14 68 2.828E8 73.54 38.05 14 34 5308.51 38.05 14 34 431 47.1 4.37 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 68 5.589E8 67.14 35.50 8 33 4651.23 38.05 9 35 431 46.1 4.48 HVO_1084 adenylosuccinate lyase 38.01 1 15 15 53 2.819E8 47.70 32.83 13 25 3689.09 38.01 15 28 463 50.8 4.70 HVO_0243 threonine aldolase 37.83 1 10 10 33 7.637E7 29.00 37.83 10 17 2103.08 37.83 10 16 341 35.6 4.55 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 37.77 1 1 24 122 4.615E8 110.45 37.77 24 61 7701.89 37.77 24 61 564 60.0 8.00 HVO_1187 conserved hypothetical protein 37.76 1 5 5 12 1.347E7 6.74 37.76 5 6 478.57 37.76 5 6 143 16.4 4.86 HVO_2717 alanine--tRNA ligase 37.69 1 12 12 31 1.033E8 23.44 34.67 11 15 2075.39 34.42 10 16 398 41.6 4.39 HVO_0008 aspartate kinase 37.50 1 10 10 55 1.082E9 43.31 37.50 10 27 3156.60 37.50 10 28 392 41.7 4.46 HVO_1550 acyl-CoA thioester hydrolase 37.50 1 4 4 14 1.113E8 9.94 30.63 3 6 1213.80 37.50 4 8 160 17.6 4.55 HVO_1459 ThuA family protein 37.39 1 4 4 22 2.360E8 29.45 37.39 4 12 1697.51 22.69 3 10 238 26.8 4.67 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 37.31 1 3 3 7 1.392E7 6.38 30.60 2 3 506.24 37.31 3 4 134 13.9 4.55 HVO_2759 peptidase M42 family protein 37.01 1 10 10 34 5.290E7 32.61 37.01 10 17 2176.36 37.01 10 17 354 37.0 4.40 HVO_1076 sugar nucleotidyltransferase 36.96 1 8 8 36 3.763E8 42.70 36.96 8 20 2609.58 27.33 6 16 322 35.8 4.20 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 36.84 1 5 5 31 3.854E8 26.91 36.84 5 16 2119.21 36.84 5 15 190 20.6 4.30 HVO_1295 histidinol-phosphate aminotransferase 36.84 1 10 10 28 1.237E8 20.91 30.47 9 14 1404.14 36.84 10 14 361 39.4 4.51 HVO_0406 RNA-binding protein AU-1 36.75 1 12 12 38 1.143E8 26.40 36.75 12 19 2004.05 36.75 12 19 468 49.9 4.53 HVO_1123 thioredoxin-disulfide reductase 36.68 1 9 9 36 4.212E8 37.02 33.52 8 16 2530.42 36.68 9 20 349 37.3 4.32 HVO_2773 30S ribosomal protein S2 36.54 1 7 7 43 1.653E9 53.02 36.54 7 21 3357.86 36.54 7 22 260 28.3 4.16 HVO_0100 NMD3 family protein 36.53 1 8 8 31 8.884E7 38.62 36.53 8 16 2175.28 36.53 8 15 375 41.6 4.46 HVO_0041 ornithine carbamoyltransferase 36.45 1 7 7 44 2.116E8 47.64 36.45 7 21 2895.20 36.45 7 23 299 32.7 4.37 HVO_1957 proteasome-activating nucleotidase 36.41 1 10 11 34 1.308E8 16.72 32.52 10 17 1326.92 36.41 11 17 412 45.6 4.48 HVO_2380 AAA-type ATPase (CDC48 subfamily) 36.34 1 21 21 72 7.652E7 54.76 36.34 21 36 3963.98 36.34 21 36 743 81.9 4.82 HVO_1371 glutamate 5-kinase 36.21 1 9 9 34 2.380E8 29.42 34.55 8 16 2202.20 36.21 9 18 301 32.0 4.25 HVO_2721 amidophosphoribosyltransferase 36.11 1 11 11 47 4.448E8 38.91 36.11 11 23 3017.00 36.11 11 24 493 53.4 4.78 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 36.08 1 4 4 34 7.410E8 37.71 25.26 3 14 3455.68 36.08 4 20 194 20.7 4.12 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 35.99 1 0 23 118 4.615E8 104.75 35.99 23 59 7453.18 35.99 23 59 564 60.2 8.00 HVO_0138 tyrosine--tRNA ligase 35.98 1 7 7 35 3.350E8 28.74 35.98 7 18 1896.34 29.57 6 17 328 36.1 4.34 HVO_2813 RimK family protein 35.98 1 13 13 72 4.463E8 73.72 35.98 13 36 4962.20 35.98 13 36 453 49.0 4.73 HVO_0694 probable phosphoribosyltransferase 35.86 1 7 7 25 5.675E7 21.96 31.22 6 12 1463.22 35.86 7 13 237 27.0 4.32 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 35.56 1 8 8 31 1.448E8 36.63 35.56 8 16 2380.66 35.56 8 15 270 29.1 4.35 HVO_B0060 precorrin-4 C11-methyltransferase 35.48 1 5 5 16 1.163E8 6.53 35.48 5 8 736.12 35.48 5 8 279 29.7 4.22 HVO_0549 2-keto-3-deoxygluconate kinase 35.31 1 9 10 38 2.429E8 27.81 31.56 9 18 2824.13 35.31 10 20 320 34.1 4.34 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 35.31 1 13 13 43 1.276E8 41.52 28.54 12 21 2561.87 35.31 13 22 473 50.8 4.58 HVO_2205 arNOG06768 family NADH-binding domain protein 35.22 1 7 7 24 2.705E7 20.31 35.22 7 12 1471.41 35.22 7 12 301 32.0 5.00 HVO_2883 conserved hypothetical protein 35.19 1 17 17 59 7.178E7 57.76 35.19 17 29 4019.76 35.19 17 30 702 78.9 4.48 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 35.15 1 7 7 25 1.408E8 26.15 35.15 7 13 1577.08 35.15 7 12 330 36.3 4.35 HVO_1778 catalase-peroxidase 35.10 1 18 18 69 5.612E8 78.70 32.45 17 34 5027.57 35.10 18 35 718 80.0 4.31 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 35.09 1 8 8 28 1.122E8 23.08 35.09 8 14 2025.34 35.09 8 14 265 28.7 4.87 HVO_1291 fumarylacetoacetase family protein 34.98 1 5 5 28 4.318E8 31.36 34.98 5 14 2074.30 34.98 5 14 243 26.3 4.55 HVO_1481 UspA domain protein 34.97 1 4 4 15 2.057E8 17.43 28.83 3 7 941.46 34.97 4 8 163 17.7 4.40 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 34.78 1 6 7 29 4.518E8 16.43 27.67 5 13 1870.15 34.78 7 16 253 26.0 4.60 HVO_1370 gamma-glutamyl phosphate reductase 34.68 1 13 13 51 2.447E8 45.10 34.68 13 26 3286.40 34.68 13 25 444 48.1 4.34 HVO_1867 lysine--tRNA ligase 34.59 1 15 15 49 1.222E8 41.30 32.97 14 24 2803.37 34.59 15 25 555 62.1 4.46 HVO_0321 peptide chain release factor aRF-1 34.54 1 11 12 42 1.482E8 21.27 33.09 11 20 2097.50 34.54 12 22 414 46.6 4.83 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 34.43 1 10 10 40 1.299E8 24.89 34.43 10 20 2093.98 34.43 10 20 427 45.4 4.56 HVO_1783 conserved hypothetical protein 34.38 1 5 5 20 3.025E7 10.40 34.38 5 10 950.98 34.38 5 10 224 24.1 5.90 HVO_2417 conserved hypothetical protein 34.36 1 5 5 18 1.800E8 16.47 34.36 5 9 1426.96 34.36 5 9 195 21.6 3.65 HVO_1804 nicotinate phosphoribosyltransferase 34.28 1 10 10 26 1.010E8 29.57 27.06 8 12 2084.87 31.96 9 14 388 41.1 4.60 21961227 Keratin 6B [Homo sapiens] 34.22 1 1 22 121 5.103E8 111.29 34.22 22 61 7643.04 34.22 22 60 564 60.0 8.00 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 34.22 1 0 22 116 4.615E8 105.36 34.22 22 58 7420.27 34.22 22 58 564 60.0 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 34.22 1 0 22 114 4.615E8 100.33 34.22 22 57 7139.81 34.22 22 57 564 60.0 7.72 7428712 "keratin 1, type II, cytoskeletal - human" 34.21 1 0 24 196 1.108E9 208.15 34.21 24 98 14082.56 34.21 24 98 643 65.5 6.35 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 34.04 1 5 5 21 2.246E8 11.77 34.04 5 10 1208.46 34.04 5 11 188 20.5 4.60 HVO_2662 homolog to lactoylglutathione lyase 34.04 1 7 7 27 8.487E7 19.91 34.04 7 13 1668.95 34.04 7 14 329 36.5 4.48 HVO_2708 YfiH family protein 33.85 1 7 7 21 3.344E8 27.06 33.85 7 11 2000.28 29.50 6 10 322 35.4 4.35 HVO_2425 GNAT family acetyltransferase 33.80 1 6 6 22 9.672E7 14.06 33.80 6 11 1484.18 33.80 6 11 216 24.4 4.54 HVO_2562 50S ribosomal protein L23 33.73 1 3 3 7 7.157E6 5.06 33.73 3 4 328.68 24.10 2 3 83 9.4 5.48 HVO_2313 siroheme decarboxylase AhbB 33.71 1 7 8 25 1.569E8 24.43 33.71 8 13 1583.10 32.01 7 12 353 39.6 4.64 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 33.62 1 12 12 70 1.903E8 18.19 33.62 12 35 2850.82 33.62 12 35 461 50.7 4.73 HVO_0484 50S ribosomal protein L10e 33.52 1 5 5 14 5.964E7 9.96 33.52 5 7 860.08 33.52 5 7 176 19.8 8.72 HVO_0354 30S ribosomal protein S7 33.33 1 6 6 17 1.781E8 14.47 21.57 4 7 1440.35 33.33 6 10 204 22.6 5.14 HVO_1577 conserved hypothetical protein 33.33 1 6 6 23 1.500E8 26.88 23.16 4 10 1751.25 33.33 6 13 177 19.4 4.74 HVO_2690 GFO family oxidoreductase 33.33 1 9 9 40 4.175E8 29.60 33.33 9 20 2340.04 24.59 8 20 366 40.0 4.60 HVO_A0266 IclR family transcription regulator 33.33 1 7 7 20 3.486E7 13.98 33.33 7 10 1012.84 33.33 7 10 255 27.7 6.05 HVO_A0350 conserved hypothetical protein 33.33 1 8 8 30 8.828E7 17.51 33.33 8 15 1513.87 33.33 8 15 213 23.8 9.64 HVO_2781 DNA-directed RNA polymerase subunit D 33.20 1 7 7 40 5.725E8 32.79 28.96 6 18 3031.35 33.20 7 22 259 28.1 4.32 HVO_1250 redoxin domain protein 33.16 1 3 3 9 3.541E7 7.34 27.27 2 4 817.47 33.16 3 5 187 20.5 4.03 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 33.11 1 11 11 55 2.936E8 52.92 33.11 11 29 3513.49 33.11 11 26 447 48.5 4.56 HVO_0049 argininosuccinate synthase 33.09 1 12 12 57 9.801E8 39.82 28.15 11 29 3158.42 33.09 12 28 405 44.5 4.34 HVO_0401 UspA domain protein 32.89 1 2 3 12 1.372E8 9.86 32.89 3 6 695.03 32.89 3 6 152 16.4 4.79 HVO_0467 PhoU/TrkA-C domain protein 32.84 1 12 12 34 5.619E7 29.09 30.85 11 17 1960.35 30.85 11 17 402 43.3 4.49 HVO_0017 conserved hypothetical protein 32.81 1 5 5 16 6.583E7 7.48 32.81 5 9 745.95 21.88 4 7 192 21.9 4.50 HVO_1465 naphthoate synthase 32.79 1 7 7 24 7.640E7 24.08 32.79 7 12 1491.02 32.79 7 12 305 33.9 4.83 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 32.77 1 9 9 41 5.073E8 41.16 28.19 8 20 2632.49 32.77 9 21 415 44.4 4.41 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 32.76 1 14 14 59 1.638E8 44.37 32.76 14 30 3377.32 31.06 13 29 586 63.4 4.70 HVO_1172 NAD-dependent epimerase/dehydratase 32.70 1 9 9 39 6.389E8 31.26 30.16 8 17 3062.74 32.70 9 22 315 34.9 4.34 HVO_2156 UspA domain protein 32.56 1 7 7 25 2.480E8 28.92 29.90 6 12 2081.77 32.56 7 13 301 31.6 4.69 386849 keratin type II 32.50 1 0 19 83 4.092E8 81.00 32.50 19 42 5472.74 32.50 19 41 563 59.9 7.94 HVO_0452 leucine--tRNA ligase 32.46 1 24 24 103 3.792E8 84.49 32.46 24 51 7009.31 29.44 23 52 958 109.5 4.37 HVO_1500 1-phosphofructokinase 32.46 1 7 7 25 4.388E7 16.31 32.46 7 13 1090.62 23.28 6 12 305 32.0 4.51 HVO_2948 phenylalanine--tRNA ligase alpha subunit 32.46 1 9 9 45 2.837E8 40.79 32.46 9 22 2654.14 32.46 9 23 499 55.1 4.41 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 32.43 1 12 12 86 7.793E8 66.33 32.43 12 44 5392.66 32.43 12 42 370 41.9 4.48 HVO_1198 UspA domain protein 32.41 1 4 4 14 2.321E8 11.20 32.41 4 7 725.82 32.41 4 7 145 15.6 4.75 HVO_1660 DisA-N domain protein 32.34 1 7 7 24 1.240E8 27.07 32.34 7 12 1630.95 32.34 7 12 269 28.9 4.73 HVO_B0371 aldehyde dehydrogenase 32.26 1 8 8 26 4.814E7 26.84 27.82 7 13 1807.99 30.65 7 13 496 52.5 4.39 40354192 keratin 10 [Homo sapiens] 32.19 1 0 18 76 6.004E8 65.76 32.19 18 38 4518.59 32.19 18 38 584 58.8 5.16 HVO_C0069 GFO family oxidoreductase 32.10 1 9 9 32 8.583E7 25.00 29.94 8 15 1854.30 32.10 9 17 324 36.0 5.10 HVO_1547 isoleucine--tRNA ligase 31.93 1 22 22 114 6.361E8 118.77 31.83 21 57 7745.71 28.76 21 57 1043 117.9 4.30 HVO_1573 DNA gyrase subunit A 31.79 1 25 25 101 3.343E8 80.40 30.86 24 51 6071.09 31.67 24 50 862 94.8 4.56 HVO_0788 tryptophan synthase beta subunit 31.75 1 11 11 49 2.099E8 39.50 31.75 11 25 2718.46 31.75 11 24 422 45.7 4.65 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 31.70 1 0 18 76 6.004E8 65.76 31.70 18 38 4518.59 31.70 18 38 593 59.5 5.21 HVO_A0458 ParA domain protein 31.62 1 6 6 17 4.590E7 19.30 31.62 6 9 1058.03 31.62 6 8 291 32.2 4.79 HVO_1878 NAD synthase 31.52 1 7 7 25 1.401E8 18.74 22.46 6 12 1661.48 31.52 7 13 276 29.6 4.37 HVO_1816 dihydroorotase 31.47 1 9 9 32 7.741E7 35.28 29.60 8 15 2299.36 31.47 9 17 429 45.4 4.40 HVO_2580 L-aspartate oxidase 31.47 1 13 13 47 6.660E7 40.72 31.47 13 24 2966.95 31.47 13 23 537 55.8 4.63 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 19 1.007E9 20.52 31.45 3 9 1383.40 31.45 3 10 124 14.2 5.22 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 31.35 1 6 6 18 1.145E8 2.11 31.35 6 9 663.12 31.35 6 9 386 42.1 4.49 HVO_1097 diaminopimelate epimerase 31.25 1 6 6 15 7.134E7 14.35 27.78 5 7 1105.90 31.25 6 8 288 29.9 4.48 HVO_1391 NUDIX family hydrolase 31.13 1 4 4 13 2.688E7 11.19 31.13 4 7 778.45 27.15 3 6 151 17.4 5.01 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 31.05 1 27 27 119 3.671E8 114.97 28.84 25 56 8783.46 31.05 27 63 1082 117.2 4.32 HVO_2779 50S ribosomal protein L18e 31.03 1 4 4 14 1.195E7 12.79 31.03 4 7 782.50 31.03 4 7 116 12.7 8.50 HVO_0601 homoserine dehydrogenase 31.01 1 5 5 19 1.595E8 31.16 27.53 4 9 2197.86 31.01 5 10 316 32.2 4.25 HVO_0551 DNA mismatch repair protein MutL 30.88 1 15 15 39 6.415E7 22.07 28.57 14 19 2405.26 30.88 15 20 735 78.7 4.50 HVO_1576 NAD-dependent epimerase/dehydratase 30.72 1 4 9 38 4.263E8 23.80 30.72 9 19 2304.88 30.72 9 19 306 33.9 4.51 HVO_1654 cysteine synthase 30.72 1 8 8 26 1.267E8 16.84 27.78 7 12 1540.73 30.72 8 14 306 32.3 4.32 HVO_B0018 ParA domain protein 30.66 1 5 5 22 5.771E7 13.54 30.66 5 11 1153.49 30.66 5 11 287 31.7 4.74 HVO_A0021 conserved hypothetical protein 30.53 1 4 4 11 3.620E7 5.92 24.43 3 4 584.20 30.53 4 7 131 14.9 4.42 HVO_2923 proteasome alpha subunit 30.52 1 5 6 16 1.357E8 14.83 30.52 6 8 904.13 30.52 6 8 249 26.7 4.39 HVO_0795 transcription initiation factor TFB 30.45 1 7 10 35 1.114E8 26.46 30.45 10 17 1916.06 30.45 10 18 335 37.4 5.59 HVO_0911 GTP-binding protein Drg 30.35 1 10 10 28 2.716E7 21.39 30.35 10 13 1804.74 30.35 10 15 369 40.5 4.81 HVO_1508 acetolactate synthase large subunit 30.32 1 10 10 35 1.849E8 46.21 30.32 10 18 2617.97 26.75 9 17 587 62.3 4.36 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 30.31 1 16 16 59 2.049E8 50.35 27.05 14 28 3819.58 30.31 16 31 706 73.3 4.39 HVO_2496 adenylate kinase 30.29 1 5 5 26 4.124E8 24.63 30.29 5 13 1831.13 30.29 5 13 208 23.1 4.25 HVO_1932 2-D-hydroxyacid dehydrogenase 30.19 1 8 8 32 1.201E8 28.92 30.19 8 16 1869.16 30.19 8 16 308 33.0 4.60 HVO_2333 conserved hypothetical protein 30.19 1 8 8 23 3.989E7 8.61 30.19 8 11 917.56 30.19 8 12 308 34.9 4.54 HVO_2758 50S ribosomal protein L11 30.19 1 3 3 5 5.763E7 542.33 30.19 3 5 159 16.8 4.04 HVO_1871 UPF0447 family protein 30.14 1 12 12 40 1.851E8 34.41 25.15 10 19 2553.90 27.35 11 21 501 56.1 4.59 47132620 keratin 2a [Homo sapiens] 30.05 1 11 18 88 8.000E8 83.43 30.05 18 44 6348.94 30.05 18 44 639 65.4 8.00 HVO_1683 4-alpha-glucanotransferase 30.04 1 12 12 35 6.842E7 18.31 30.04 12 17 1523.36 30.04 12 18 496 56.3 4.45 HVO_2347 conserved hypothetical protein 30.00 1 3 3 8 1.614E7 7.26 30.00 3 4 517.69 30.00 3 4 140 15.5 4.37 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 29.88 1 11 11 44 1.464E8 47.89 29.88 11 22 3396.56 29.88 11 22 512 53.8 4.78 HVO_1858 30S ribosomal protein S19e 29.80 1 2 2 4 2.269E7 416.37 29.80 2 4 151 16.7 4.84 HVO_1478 transcription initiation factor TFB 29.65 1 5 9 38 2.122E8 33.58 29.65 9 19 2698.26 29.65 9 19 317 35.7 5.47 HVO_2913 superoxide dismutase (Mn) 29.65 1 0 3 16 1.545E9 21.90 29.65 3 8 1513.10 29.65 3 8 199 22.3 4.48 HVO_A0406 conserved hypothetical protein 29.63 1 1 8 33 1.791E8 33.81 29.63 8 17 2095.91 29.63 8 16 405 44.4 5.30 HVO_1568 alpha/beta hydrolase fold protein 29.60 1 6 6 22 3.027E7 16.61 29.60 6 11 1187.72 29.60 6 11 277 29.4 4.94 HVO_1348 probable YjeF family carbohydrate kinase 29.50 1 10 10 34 1.006E8 38.12 29.50 10 17 2482.26 29.50 10 17 478 48.8 4.45 HVO_A0475 superoxide dismutase (Mn) 29.50 1 0 3 16 1.545E9 21.90 29.50 3 8 1513.10 29.50 3 8 200 22.4 4.45 HVO_2947 phenylalanine--tRNA ligase beta subunit 29.47 1 12 12 55 1.856E8 40.97 29.47 12 27 3136.42 29.47 12 28 570 63.3 4.46 HVO_0360 30S ribosomal protein S10 29.41 1 3 3 10 4.344E7 10.00 29.41 3 5 679.66 29.41 3 5 102 11.5 4.88 HVO_0989 conserved hypothetical protein 29.37 1 4 4 9 5.574E7 2.59 23.02 3 4 480.47 29.37 4 5 126 14.4 4.81 HVO_1488 D-gluconate dehydratase 29.37 1 8 10 80 5.809E8 71.55 29.37 10 39 5235.13 29.37 10 41 412 45.8 4.60 HVO_A0496 UspA domain protein 29.31 1 7 7 30 1.194E8 31.54 29.31 7 15 1745.92 29.31 7 15 290 31.4 4.60 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 29.21 1 5 6 15 9.018E7 6.21 22.85 5 8 565.91 26.59 5 7 267 29.1 4.63 HVO_2536 CHP00300 family protein 29.09 1 7 7 20 9.180E7 14.40 29.09 7 10 1060.45 29.09 7 10 416 44.8 4.51 HVO_0048 argininosuccinate lyase 28.89 1 10 10 39 6.205E7 47.70 28.89 10 19 2985.36 28.89 10 20 488 50.8 4.53 HVO_1327 AAA-type ATPase (CDC48 subfamily) 28.80 1 13 14 45 9.816E7 32.11 27.72 13 21 2291.60 26.77 13 24 736 78.1 4.88 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 28.77 1 4 4 16 3.723E7 19.39 28.77 4 8 1007.58 28.77 4 8 219 22.4 4.06 HVO_1657 phosphoribosylamine--glycine ligase 28.74 1 11 11 59 5.584E8 38.93 28.74 11 30 3074.11 27.34 10 29 428 45.5 4.20 HVO_1553 hydroxypyruvate reductase 28.73 1 10 10 25 6.870E7 12.13 22.62 8 11 1333.57 28.73 10 14 442 45.2 4.50 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 28.70 1 4 15 53 6.310E8 48.76 27.08 14 27 3071.61 24.31 13 26 432 48.1 5.02 HVO_1079 sulfate adenylyltransferase small subunit 28.62 1 7 7 24 1.445E8 28.20 28.62 7 12 1617.08 28.62 7 12 325 37.5 4.18 HVO_1496 phosphotransferase system component I 28.50 1 12 12 48 2.432E8 54.86 28.50 12 24 3469.19 28.50 12 24 565 60.3 4.21 HVO_2436 malic enzyme (NADP) 28.36 1 15 19 77 1.586E8 87.58 27.56 18 38 5342.99 28.36 19 39 751 81.4 4.55 HVO_2912 ThiJ/PfpI domain protein 28.36 1 3 3 8 4.235E7 7.57 28.36 3 4 411.45 28.36 3 4 201 20.9 4.36 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 28.09 1 7 7 26 6.043E7 16.10 28.09 7 13 1443.09 28.09 7 13 324 36.6 4.68 HVO_0357 ACT domain protein 28.04 1 5 5 19 2.018E8 12.24 28.04 5 10 1147.85 28.04 5 9 189 20.2 4.59 HVO_2879 ornithine cyclodeaminase 28.01 1 6 6 21 1.833E8 16.24 20.48 5 9 1375.03 28.01 6 12 332 34.6 4.45 HVO_1139 squalene synthase 27.93 1 5 5 20 1.049E8 11.82 27.93 5 10 916.21 27.93 5 10 358 39.7 4.54 4557890 keratin 5 [Homo sapiens] 27.80 1 0 18 95 4.582E8 86.45 27.80 18 47 6120.01 27.80 18 48 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 27.80 1 0 18 95 4.582E8 86.45 27.80 18 47 6120.01 27.80 18 48 590 62.4 8.06 HVO_2643 NADPH:quinone reductase 27.75 1 6 6 31 1.015E8 22.30 27.75 6 16 1738.09 19.94 5 15 346 37.2 4.55 HVO_2790 ATP-binding protein Mrp 27.75 1 6 6 23 1.009E8 28.33 27.75 6 11 1636.97 27.75 6 12 346 36.8 4.50 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 27.59 1 8 8 54 5.861E8 48.97 27.59 8 27 3491.08 27.59 8 27 435 46.9 4.63 HVO_1164 HD family hydrolase 27.41 1 7 7 30 1.679E8 21.87 27.41 7 15 1902.20 27.41 7 15 270 29.8 4.87 HVO_2712 3'-5' RNA ligase 27.37 1 10 10 37 8.869E7 30.01 27.37 10 19 2178.82 25.72 9 18 486 53.4 4.92 HVO_1125 cysteine--tRNA ligase 27.33 1 10 10 44 1.192E8 45.90 27.33 10 22 2971.16 27.33 10 22 494 55.2 4.56 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 27.32 1 5 5 24 1.307E8 19.80 27.32 5 12 1774.10 27.32 5 12 377 39.2 4.18 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 27.20 1 8 8 44 2.009E8 52.78 27.20 8 22 3600.15 27.20 8 22 364 39.3 4.35 HVO_2688 TrmB family transcription regulator 27.20 1 9 9 32 3.004E8 27.09 27.20 9 16 2378.53 27.20 9 16 353 39.3 4.58 HVO_0573 endonuclease IV 27.15 1 5 5 24 3.097E8 22.43 27.15 5 12 1612.67 27.15 5 12 291 31.4 4.44 HVO_0699 translation initiation factor aIF-2 alpha subunit 27.07 1 6 6 28 1.982E8 24.28 27.07 6 14 2084.81 27.07 6 14 266 29.5 4.46 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 26.92 1 4 4 14 6.311E7 18.22 26.92 4 7 1253.58 26.92 4 7 208 22.6 4.36 HVO_0997 peptidase M24 family protein 26.90 1 6 6 19 6.297E7 11.95 26.90 6 10 1130.81 26.90 6 9 368 39.9 4.49 HVO_0122 phosphoglycerate dehydrogenase 26.85 1 6 6 24 9.400E7 18.74 26.85 6 12 1217.80 26.85 6 12 324 35.3 5.35 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 26.77 1 4 4 14 1.042E8 8.15 26.77 4 7 815.98 26.77 4 7 269 28.3 4.49 HVO_1491 HAD superfamily hydrolase 26.72 1 10 10 31 7.318E7 21.06 26.72 10 16 1594.39 25.00 9 15 408 44.4 4.60 HVO_C0001 Orc1-type DNA replication protein 26.72 1 11 11 36 4.546E7 24.63 26.72 11 18 1847.87 26.72 11 18 408 45.2 4.97 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 26.59 1 6 6 29 3.375E8 25.23 26.59 6 14 1961.55 26.59 6 15 252 26.0 4.39 HVO_0970 ribulose-bisphosphate carboxylase large subunit 26.57 1 10 10 70 1.901E8 66.37 26.57 10 35 4734.98 26.57 10 35 414 43.9 4.59 HVO_0179 Lrp/AsnC family transcription regulator / TrkA domain protein 26.44 1 6 6 15 5.928E7 9.97 26.44 6 8 661.66 23.37 5 7 261 28.0 4.58 HVO_0681 DNA topoisomerase I 26.43 1 16 16 48 9.964E7 40.85 26.43 16 24 3055.13 25.60 15 24 840 93.6 4.58 HVO_2481 HD family hydrolase 26.41 1 7 7 23 6.408E7 5.74 23.85 6 10 851.77 26.41 7 13 390 42.7 6.14 HVO_0511 NAD-dependent epimerase/dehydratase 26.34 1 5 5 19 4.740E7 14.27 26.34 5 10 1151.29 21.76 4 9 262 29.3 4.78 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 26.31 1 9 9 33 1.948E8 25.08 26.31 9 17 1989.79 24.02 8 16 612 67.3 4.16 HVO_2183 aldehyde ferredoxin oxidoreductase 26.13 1 12 12 32 4.405E7 26.53 24.73 11 15 2198.18 24.42 11 17 643 69.3 4.59 HVO_0812 phosphoenolpyruvate synthase 26.02 1 17 17 55 8.619E7 49.30 24.44 15 27 3413.38 24.84 16 28 761 83.1 4.63 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 25.90 1 5 5 18 8.061E7 16.87 25.90 5 9 1154.25 25.90 5 9 305 32.7 4.56 HVO_0466 citrate (si)-synthase 25.86 1 8 8 47 3.652E8 42.89 25.86 8 24 3132.98 25.86 8 23 379 41.8 4.55 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 25.84 1 5 6 18 4.377E7 18.42 25.84 6 10 894.84 17.60 5 8 267 28.8 4.55 HVO_0123 signal recognition particle 54K protein 25.81 1 12 12 37 9.329E7 27.22 24.30 11 18 2311.15 25.81 12 19 465 50.9 4.50 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 25.62 1 27 27 104 2.005E8 81.39 25.00 26 51 5731.66 25.62 27 53 1284 141.2 4.35 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 25.49 1 7 7 25 2.173E8 22.00 22.97 6 12 1522.33 25.49 7 13 357 39.8 4.41 HVO_A0307 Lrp/AsnC family transcription regulator 25.42 1 4 4 10 3.848E7 5.72 25.42 4 5 551.19 25.42 4 5 177 19.4 4.39 HVO_2256 DUF262 family protein 25.32 1 11 11 39 1.113E8 27.58 25.32 11 19 2279.49 25.32 11 20 462 54.9 4.89 HVO_2008 archaeosine synthase 25.30 1 13 13 37 1.998E8 27.90 25.30 13 19 2141.15 25.30 13 18 585 64.9 4.81 HVO_1711 glucoamylase 25.28 1 29 29 91 8.198E7 72.87 25.28 29 45 5207.88 23.69 28 46 1511 166.1 4.64 HVO_0889 FAD-dependent oxidoreductase 25.23 1 3 3 15 7.837E7 17.41 25.23 3 7 1224.79 25.23 3 8 214 21.8 3.89 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 25.23 1 8 8 32 8.217E7 29.56 25.23 8 16 2203.71 25.23 8 16 333 36.7 4.56 HVO_1048 phosphoribosylformylglycinamidine synthase 2 25.21 1 12 12 67 3.871E8 84.37 24.22 11 32 5663.47 25.21 12 35 702 72.9 4.18 >sp|TRYP_PIG| 25.11 1 4 4 60 1.301E10 81.93 25.11 4 30 4915.68 25.11 4 30 231 24.4 7.18 HVO_0658 tRNA pseudouridine(13) synthase TruD 25.05 1 7 7 28 1.221E8 24.45 25.05 7 15 1451.26 25.05 7 13 463 50.6 4.70 HVO_1574 NUDIX family hydrolase 25.00 1 3 3 8 1.075E7 8.12 25.00 3 4 673.03 25.00 3 4 156 17.6 4.98 HVO_A0133 conserved hypothetical protein 25.00 1 6 6 24 1.193E8 24.64 25.00 6 12 1737.47 25.00 6 12 292 30.8 5.17 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 24.93 1 7 7 19 4.783E7 19.39 24.93 7 10 1129.57 20.29 6 9 345 36.9 4.68 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 24.93 1 7 7 34 1.201E8 36.27 24.93 7 17 2284.70 24.93 7 17 349 37.0 4.70 HVO_1880 conserved hypothetical protein 24.89 1 5 5 13 2.599E7 11.15 22.22 4 6 960.73 24.89 5 7 225 23.8 4.59 HVO_3014 origin-associated GTP-binding protein OapA 24.88 1 5 5 14 5.092E7 7.02 18.31 3 6 819.23 24.88 5 8 213 24.0 5.01 HVO_0854 DNA double-strand break repair ATPase Rad50 24.86 1 20 20 65 1.321E8 58.70 24.86 20 32 3945.09 24.08 19 33 893 100.0 4.58 HVO_1727 TATA-binding transcription initiation factor 24.73 1 4 4 24 5.542E8 14.05 24.73 4 12 1309.93 24.73 4 12 186 19.9 4.36 HVO_1527 glucose-1-phosphate uridylyltransferase 24.69 1 7 7 30 1.943E8 18.85 24.69 6 14 1579.88 24.69 7 16 243 27.5 4.70 HVO_2467 NADPH:quinone reductase 24.61 1 6 6 19 8.943E7 8.50 19.63 5 9 1043.53 24.61 6 10 321 33.0 4.51 HVO_2793 conserved hypothetical protein 24.60 1 4 4 14 3.435E7 11.51 24.60 4 7 686.57 24.60 4 7 252 27.1 4.46 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 24.55 1 5 5 12 7.854E7 7.88 20.58 4 5 913.36 24.55 5 7 277 30.6 4.30 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 24.53 1 15 15 67 3.625E8 60.85 24.53 15 33 5001.93 24.53 15 34 697 74.5 4.13 HVO_1866 uridylate kinase 24.47 1 4 4 24 2.556E8 23.15 24.47 4 12 1687.81 24.47 4 12 237 24.6 4.42 HVO_0536 ferritin 24.43 1 2 2 8 5.321E7 12.41 24.43 2 4 577.94 24.43 2 4 176 19.9 4.50 HVO_1531 UDP-glucose 6-dehydrogenase 24.42 1 8 8 29 9.569E7 24.51 20.70 7 14 1894.50 24.42 8 15 430 45.9 4.50 HVO_0552 DNA mismatch repair protein MutS 24.03 1 17 17 47 1.052E8 47.30 22.62 16 23 3273.44 21.97 16 24 924 99.2 4.65 HVO_2383 DNA repair and recombination protein RadB 24.02 1 5 5 15 3.059E7 12.08 24.02 5 8 878.16 19.65 4 7 229 24.6 5.02 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 23.97 1 10 10 28 8.661E7 32.56 23.97 10 14 2017.28 23.97 10 14 634 66.1 4.54 HVO_A0432 conserved hypothetical protein 23.95 1 0 7 27 1.233E8 31.14 23.95 7 14 1949.95 23.95 7 13 405 44.5 5.24 HVO_2716 acyl-CoA dehydrogenase 23.88 1 6 6 26 5.332E7 28.35 23.88 6 13 1794.04 23.88 6 13 381 41.3 4.65 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 23.84 1 7 7 24 7.417E7 18.54 20.64 6 11 2249.54 23.84 7 13 344 39.1 4.73 HVO_2648 phosphoglycerate dehydrogenase 23.82 1 6 6 24 5.046E7 9.74 21.00 5 11 1105.53 23.82 6 13 319 34.2 4.64 HVO_B0114 IclR family transcription regulator 23.81 1 6 6 14 1.596E7 10.86 23.81 6 7 738.33 23.81 6 7 252 28.4 5.44 HVO_1373 acyl-CoA dehydrogenase 23.76 1 6 6 26 1.215E8 30.51 23.76 6 13 1909.28 23.76 6 13 383 42.5 4.61 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 23.74 1 10 10 41 1.545E8 32.67 23.74 10 20 2205.05 23.74 10 21 615 67.6 4.88 HVO_0358 homoserine dehydrogenase 23.66 1 5 5 34 2.442E8 35.08 23.66 5 17 2606.41 23.66 5 17 317 32.4 4.44 HVO_0697 PAC2 family protein 23.53 1 3 3 16 1.456E8 24.05 23.53 3 8 1783.96 23.53 3 8 255 27.4 4.08 HVO_2951 tryptophan--tRNA ligase 23.44 1 8 8 29 9.083E7 10.54 23.44 8 15 1138.59 18.71 7 14 529 59.1 4.53 HVO_2707 GFO family oxidoreductase 23.39 1 7 7 20 1.471E8 25.57 23.39 7 10 1595.44 23.39 7 10 372 41.0 4.55 HVO_0680 (S)-3-O-geranylgeranylglyceryl phosphate synthase 1 23.33 1 3 3 7 7.159E7 8.31 18.33 2 3 450.13 23.33 3 4 240 26.5 4.17 HVO_0234 conserved hypothetical protein 23.27 1 3 3 7 3.428E7 4.90 17.82 2 3 248.04 23.27 3 4 275 28.1 4.48 HVO_1337 rpa-associated protein 23.27 1 9 9 29 1.612E8 29.11 23.27 9 15 1632.23 23.27 9 14 623 64.8 3.68 HVO_1287 PfpI family protease 23.23 1 3 3 8 3.711E7 1.70 23.23 3 4 259.00 23.23 3 4 198 21.5 4.53 HVO_0214 L-lactate dehydrogenase 23.13 1 8 8 44 8.656E8 38.32 23.13 8 21 2616.24 23.13 8 23 320 34.5 4.49 HVO_2706 translation initiation factor aIF-2B delta subunit 23.05 1 6 6 13 1.746E8 10.74 15.60 3 5 980.82 23.05 6 8 282 30.7 4.42 HVO_1453 glutamate dehydrogenase (NADP) 23.02 1 8 8 26 8.428E7 23.68 23.02 8 13 1424.75 23.02 8 13 417 45.7 4.49 HVO_1567 conserved hypothetical protein 22.98 1 4 4 12 8.776E7 6.82 22.98 4 6 581.53 22.98 4 6 235 25.7 4.36 HVO_1570 DNA topoisomerase VI subunit A 22.95 1 5 5 18 1.929E8 10.19 22.95 5 9 934.11 22.95 5 9 366 41.8 4.63 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 22.93 1 5 5 12 3.441E7 6.59 22.93 5 7 546.21 19.92 4 5 266 29.7 4.32 HVO_2427 replication factor C large subunit 22.75 1 10 10 29 4.212E7 32.83 20.70 9 14 1791.88 22.75 10 15 488 53.4 4.67 HVO_2784 30S ribosomal protein S13 22.75 1 3 3 9 3.813E7 6.37 22.75 3 5 486.07 11.98 2 4 167 18.9 5.17 HVO_C0077 sarcosine oxidase 22.74 1 5 5 16 3.904E7 12.17 22.74 5 8 984.38 22.74 5 8 387 42.9 4.70 HVO_1174 transcription initiation factor TFE 22.73 1 2 2 4 1.239E7 5.52 22.73 2 2 291.37 22.73 2 2 176 20.6 4.23 HVO_2348 GTP cyclohydrolase MptA 22.73 1 6 6 35 2.150E8 13.90 22.73 6 18 1376.66 22.73 6 17 308 33.5 4.68 HVO_0826 peptidase M42 family protein 22.70 1 5 5 18 2.044E7 18.17 22.70 5 9 1003.69 22.70 5 9 348 37.7 4.54 HVO_2610 deoxyribose-phosphate aldolase 22.64 1 2 2 6 2.116E7 2.42 22.64 2 3 209.50 22.64 2 3 212 21.9 4.23 HVO_1510 2-isopropylmalate synthase 22.50 1 7 7 27 3.723E8 22.75 21.14 6 13 1873.89 22.50 7 14 440 47.7 4.82 HVO_1629 conserved hypothetical protein 22.41 1 10 10 25 4.397E7 13.92 19.77 9 12 1184.51 21.09 9 13 531 56.3 4.69 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 22.39 1 5 5 16 2.575E7 18.81 22.39 5 8 1123.64 22.39 5 8 268 27.9 4.87 HVO_1625 conserved hypothetical protein 22.32 1 10 10 28 4.122E7 24.47 18.96 9 13 1889.21 22.32 10 15 654 70.1 4.04 HVO_2266 hypothetical protein 22.31 1 9 9 32 1.179E8 19.63 22.31 9 15 1766.94 22.31 9 17 493 56.7 4.54 HVO_B0115 fumarylacetoacetase family protein 22.26 1 5 5 19 1.053E8 23.04 22.26 5 9 1465.26 22.26 5 10 283 30.3 4.21 HVO_0853 DNA double-strand break repair protein Mre11 22.22 1 8 8 21 5.804E7 12.47 22.22 8 11 908.81 22.22 8 10 441 48.1 4.39 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 22.22 1 4 4 18 1.003E8 19.05 22.22 4 9 1247.28 22.22 4 9 324 33.6 3.99 HVO_1823 UspA domain protein 22.22 1 3 3 10 2.653E7 9.65 22.22 3 5 429.02 22.22 3 5 153 16.4 4.60 HVO_A0012 hypothetical protein 22.15 1 3 3 10 2.658E7 6.32 22.15 3 5 438.16 22.15 3 5 149 17.7 4.54 HVO_1685 conserved hypothetical protein 22.15 1 9 9 22 5.578E7 17.22 18.50 8 11 1146.42 22.15 9 11 492 54.5 5.74 HVO_1885 TrkA domain protein 22.12 1 3 3 7 1.430E7 0.00 22.12 3 3 244.18 22.12 3 4 217 23.4 4.75 HVO_B0052 PQQ repeat protein 22.09 1 7 7 22 3.102E7 16.02 22.09 7 11 1077.41 22.09 7 11 412 44.1 5.48 HVO_0876 methylglyoxal synthase 22.05 1 2 2 4 2.212E7 0.00 22.05 2 2 150.88 22.05 2 2 127 13.9 4.48 HVO_1020 HEAT-PBS family protein 21.96 1 7 7 24 6.216E7 25.07 21.96 7 12 2020.23 21.96 7 12 419 45.5 3.95 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 21.94 1 10 10 38 1.529E8 24.13 21.94 10 19 2038.27 21.94 10 19 661 71.0 4.35 HVO_1025 acetyl-CoA C-acyltransferase 21.93 1 7 8 21 2.582E8 21.80 21.93 7 10 1410.87 21.93 8 11 383 40.7 4.56 HVO_2702 alpha/beta hydrolase fold protein 21.92 1 5 5 22 4.847E7 6.36 20.00 4 10 1046.82 21.92 5 12 260 28.0 4.53 HVO_1412 diphosphomevalonate decarboxylase 21.91 1 7 7 33 4.752E8 13.94 21.91 7 17 1581.90 21.91 7 16 324 35.4 4.78 HVO_1562 proteasome beta subunit 21.81 1 5 5 22 5.516E7 18.24 21.81 5 11 1364.73 21.81 5 11 243 26.0 4.63 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 21.79 1 8 8 22 4.712E7 15.00 21.79 8 11 1123.14 21.79 8 11 459 50.5 4.63 HVO_0867 HD family hydrolase 21.74 1 5 5 16 5.268E7 12.33 21.74 5 8 860.04 21.74 5 8 230 26.2 4.78 HVO_B0375 Spo0M family protein 21.63 1 3 3 8 1.916E7 9.54 21.63 3 4 579.74 21.63 3 4 245 27.2 4.35 HVO_A0547 DUF1028 family protein 21.62 1 5 5 11 1.671E7 5.08 21.62 5 5 505.89 21.62 5 6 333 35.2 4.16 HVO_B0149 oleate hydratase 21.58 1 8 9 31 1.755E8 20.02 19.14 8 14 1620.04 21.58 9 17 533 60.1 4.64 HVO_2782 30S ribosomal protein S11 21.54 1 3 3 11 1.808E7 6.79 16.15 2 5 526.68 21.54 3 6 130 13.4 8.56 HVO_B0057 precorrin-3B C17-methyltransferase 21.51 1 4 4 18 2.030E8 14.67 21.51 4 9 1172.47 21.51 4 9 344 36.3 4.31 HVO_1098 diaminopimelate decarboxylase 21.45 1 7 7 23 1.327E8 14.29 21.45 7 12 1202.80 21.45 7 11 415 44.4 5.02 HVO_0087 porphobilinogen synthase 21.41 1 6 6 20 8.204E7 21.94 21.41 6 10 1371.00 21.41 6 10 327 35.3 4.72 HVO_2548 50S ribosomal protein L6 21.35 1 2 3 9 1.450E7 13.44 21.35 3 5 754.32 17.98 2 4 178 19.6 4.68 HVO_2960 dihydrolipoamide S-acyltransferase 21.31 1 10 10 36 5.308E7 20.64 21.31 10 18 1828.94 21.31 10 18 521 54.9 4.40 HVO_1087 UspA domain protein 21.28 1 4 4 12 3.673E7 10.63 21.28 4 6 822.18 21.28 4 6 141 15.2 4.98 HVO_0937 FMN-binding domain protein 21.23 1 2 2 8 2.583E7 9.03 21.23 2 4 681.02 21.23 2 4 146 16.2 4.36 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 21.14 1 4 4 16 5.230E7 10.50 21.14 4 8 705.62 21.14 4 8 175 18.8 4.63 HVO_2239 UspA domain protein 21.13 1 3 3 8 9.473E7 8.69 21.13 3 4 487.93 21.13 3 4 142 15.4 4.16 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 21.09 1 2 2 6 3.656E7 7.88 21.09 2 3 625.14 21.09 2 3 128 13.0 4.31 HVO_0818 threonine synthase 21.08 1 7 7 34 1.741E8 23.61 21.08 7 17 1888.54 21.08 7 17 389 40.8 4.31 HVO_1656 YyaL family protein 21.05 1 12 12 39 2.834E7 22.46 19.20 11 19 1785.68 21.05 12 20 703 77.3 4.49 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 20.93 1 8 8 31 1.114E8 21.00 20.93 8 15 1785.45 20.93 8 16 430 45.1 4.50 HVO_2029 Lrp/AsnC family transcription regulator 20.92 1 1 2 8 2.072E8 4.16 20.92 2 4 396.11 20.92 2 4 153 16.9 4.21 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 20.88 1 2 2 6 2.423E7 6.23 20.88 2 3 297.09 20.88 2 3 91 10.4 4.07 HVO_0233 ribose-phosphate pyrophosphokinase 20.85 1 4 4 16 9.166E7 18.62 20.85 4 8 1233.59 20.85 4 8 283 29.6 4.40 HVO_1979 tRNA pseudouridine synthase Pus10 20.84 1 7 7 29 2.040E8 27.03 20.84 7 15 1931.11 20.84 7 14 427 46.9 4.39 HVO_2068 "FtsZ family protein, type III" 20.81 1 4 4 16 7.609E7 20.70 20.81 4 8 1402.71 20.81 4 8 370 38.7 4.49 HVO_1623 conserved hypothetical protein 20.81 1 5 5 17 9.201E7 12.82 20.81 5 9 1098.39 20.81 5 8 298 32.8 4.56 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 20.75 1 7 7 36 3.179E8 30.89 20.46 6 17 2251.12 20.75 7 19 347 36.8 4.93 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 20.56 1 6 6 26 2.176E8 16.79 17.50 5 13 1414.01 20.56 6 13 360 38.5 4.45 HVO_2412 Lrp/AsnC family transcription regulator 20.50 1 3 3 6 2.015E7 4.39 20.50 3 3 246.66 20.50 3 3 161 17.7 4.55 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 20.47 1 6 6 16 3.434E7 12.83 20.47 6 8 925.50 20.47 6 8 337 35.9 4.69 HVO_1175 DUF2110 family protein 20.44 1 4 4 16 3.687E8 15.10 20.44 4 8 1205.81 20.44 4 8 225 24.4 4.63 HVO_1575 arginase 20.40 1 4 4 14 1.229E8 8.05 20.40 4 7 654.43 20.40 4 7 299 31.0 4.58 HVO_1698 CBS/parB domain protein 20.38 1 3 4 8 5.606E7 2.32 18.49 3 3 377.99 20.38 4 5 265 29.4 4.92 HVO_1847 oligoendopeptidase PepF 20.37 1 10 10 38 6.671E7 38.85 18.86 9 19 2439.12 20.37 10 19 599 68.5 4.41 HVO_B0382 TATA-binding transcription initiation factor 20.21 1 3 3 7 2.237E7 5.92 20.21 3 4 397.54 12.23 2 3 188 20.1 4.12 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 20.11 1 7 7 34 3.133E8 24.09 20.11 7 17 1725.21 20.11 7 17 373 40.2 4.44 HVO_0894 acyl-CoA synthetase 20.09 1 5 9 23 8.682E7 19.03 15.11 7 11 1583.83 18.58 8 12 662 74.3 4.48 HVO_0014 ATP-dependent DNA helicase Hel308a 20.07 1 14 14 34 4.712E7 19.95 18.98 13 17 1864.25 18.86 13 17 827 90.3 4.67 HVO_0402 DUF124 family protein 20.00 1 3 3 10 1.074E8 0.00 20.00 3 5 268.06 20.00 3 5 225 24.0 4.58 HVO_A0586 sugar nucleotidyltransferase 19.95 1 6 6 18 4.559E7 14.51 19.95 6 9 1195.49 19.95 6 9 411 43.7 4.69 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 19.94 1 3 3 10 2.218E7 9.93 19.94 3 5 635.00 19.94 3 5 336 36.0 4.51 HVO_2639 DUF1611 family protein 19.94 1 5 5 28 1.114E8 28.40 19.94 5 14 1923.41 19.94 5 14 341 36.3 4.44 HVO_2945 valine--tRNA ligase 19.89 1 16 16 61 2.173E8 45.48 18.39 15 29 4267.49 19.89 16 32 870 98.9 4.36 HVO_0042 acetylornithine deacetylase 19.69 1 6 6 18 1.572E8 13.42 19.69 6 9 970.87 19.69 6 9 381 41.0 4.34 HVO_2600 methionyl aminopeptidase 19.59 1 7 7 19 1.389E8 18.03 15.54 6 9 1349.30 17.57 6 10 296 32.3 4.41 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 19.58 1 6 6 14 4.324E7 12.96 15.67 5 7 708.66 19.58 6 7 383 42.0 4.49 HVO_0475 conserved hypothetical protein 19.55 1 3 3 5 7.286E6 4.91 19.55 3 3 174.84 10.90 2 2 312 32.5 4.74 HVO_B0001 Orc1-type DNA replication protein 19.51 1 6 7 18 4.067E7 8.50 14.39 5 8 1002.84 19.51 7 10 410 45.8 5.33 HVO_1129 conserved hypothetical protein 19.49 1 5 6 15 7.301E7 14.96 19.49 6 8 819.10 18.21 5 7 390 43.0 4.44 HVO_2001 tRNA-guanine(15) transglycosylase 19.38 1 6 6 22 9.907E7 16.85 19.38 6 11 1279.14 19.38 6 11 516 56.3 4.59 HVO_0916 diphthine synthase 19.33 1 5 5 17 9.617E7 9.12 17.10 4 8 943.18 19.33 5 9 269 29.1 4.54 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 24 4.315E8 16.31 15.61 4 11 1685.35 19.31 5 13 378 39.7 4.67 HVO_0180 23S rRNA (uridine-2'-O-) methyltransferase 19.31 1 4 4 7 3.324E7 4.00 16.22 3 3 335.68 19.31 4 4 259 28.3 4.70 HVO_1581 cytidine deaminase 19.29 1 2 2 2 1.022E7 236.60 19.29 2 2 140 15.0 4.22 HVO_1948 NUDIX family hydrolase 19.25 1 3 3 10 1.522E7 5.40 19.25 3 5 441.43 19.25 3 5 187 20.9 4.45 HVO_2153 probable copper-containing oxidoreductase 19.22 1 6 6 20 7.274E7 14.46 19.22 6 10 1055.69 19.22 6 10 385 42.1 5.82 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 19.16 1 3 4 10 8.234E7 4.87 14.94 3 5 532.14 14.18 3 5 261 27.0 4.44 HVO_2168 AAA-type ATPase (MoxR subfamily) 19.15 1 5 5 16 3.623E7 12.52 19.15 5 8 907.48 19.15 5 8 329 35.9 4.54 HVO_1925 probable GTP-binding protein 19.08 1 5 5 16 4.032E7 1.70 19.08 5 8 465.75 19.08 5 8 325 36.5 4.72 HVO_A0087 fumarylacetoacetase family protein 19.03 1 4 4 12 1.116E8 12.98 19.03 4 6 884.59 19.03 4 6 289 32.0 4.21 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 18.97 1 7 7 25 9.048E7 16.51 18.97 7 12 1237.97 18.97 7 13 464 53.1 4.54 HVO_1289 OsmC domain protein 18.94 1 2 2 30 4.934E8 45.98 18.94 2 15 3166.64 18.94 2 15 132 14.2 3.85 HVO_0034 acyl-CoA thioester hydrolase 18.90 1 3 3 24 1.061E8 17.70 18.90 3 12 1382.11 18.90 3 12 164 18.3 4.65 HVO_A0002 conserved hypothetical protein 18.75 1 2 2 6 1.599E7 3.01 18.75 2 3 385.65 18.75 2 3 192 20.7 4.02 HVO_2547 50S ribosomal protein L32e 18.72 1 3 3 14 3.415E7 14.65 18.72 3 7 1003.59 18.72 3 7 235 25.8 4.75 HVO_0195 ribose-5-phosphate isomerase 18.70 1 4 4 12 6.790E7 11.13 18.70 4 6 721.57 18.70 4 6 230 23.2 4.54 HVO_2952 tRNA-splicing endonuclease 18.58 1 5 5 14 3.915E7 13.11 18.58 5 7 978.15 18.58 5 7 339 37.4 4.74 HVO_2763 homolog to ribonuclease Z 18.55 1 4 4 11 4.764E7 9.08 16.13 3 5 542.05 18.55 4 6 248 26.6 4.53 HVO_B0130 DUF296 family protein 18.52 1 2 2 6 1.020E8 0.00 18.52 2 3 244.01 18.52 2 3 135 14.8 4.41 HVO_0979 NADH dehydrogenase-like complex subunit B 18.45 1 4 4 11 3.251E7 8.87 14.59 3 5 691.50 18.45 4 6 233 26.1 5.01 HVO_2229 flavin-containing amine-oxidoreductase 18.31 1 5 5 15 2.443E7 8.15 15.41 4 7 600.91 18.31 5 8 344 37.9 4.92 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 16 1.134E8 18.76 18.29 4 8 1258.92 18.29 4 8 257 26.8 4.01 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 18.29 1 5 5 16 1.302E8 20.39 18.29 5 8 1204.18 18.29 5 8 339 38.1 4.50 HVO_0732 "ribonuclease H, type 1" 18.27 1 3 3 6 1.010E7 1.92 18.27 3 3 307.79 18.27 3 3 197 21.5 5.07 HVO_0837 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 18.11 1 3 3 10 1.130E7 11.39 18.11 3 5 702.36 18.11 3 5 243 24.8 4.48 HVO_0639 AAA-type ATPase (MoxR subfamily) 18.04 1 5 5 24 4.803E7 9.49 18.04 5 12 1387.68 18.04 5 12 316 34.7 4.89 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 18.04 1 5 5 14 2.778E7 11.84 18.04 5 7 1056.62 18.04 5 7 327 36.0 4.73 HVO_1716 7-cyano-7-deazaguanine synthase 18.03 1 4 4 11 2.635E7 5.87 18.03 4 6 379.45 13.52 3 5 244 26.8 4.42 HVO_0429 archaemetzincin 17.92 1 2 2 6 4.394E7 7.26 17.92 2 3 465.34 17.92 2 3 173 19.3 6.54 HVO_0054 glycine--tRNA ligase 17.85 1 7 7 32 5.904E8 38.74 15.49 6 15 2714.30 17.85 7 17 594 64.9 4.21 HVO_1503 3-isopropylmalate dehydratase small subunit 17.82 1 3 3 12 1.025E8 8.95 17.82 3 6 471.76 17.82 3 6 202 22.0 4.15 HVO_0745 "FtsZ family protein, type III" 17.78 1 4 4 7 1.618E7 2.29 9.44 3 3 314.25 17.78 4 4 360 37.1 4.51 HVO_1578 probable NADH dehydrogenase 17.63 1 4 4 15 4.658E7 9.14 17.63 4 7 840.23 17.63 4 8 397 42.8 4.40 HVO_2350 YyaL family protein 17.57 1 6 6 20 4.939E7 14.14 17.57 6 10 900.52 17.57 6 10 552 58.8 4.59 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 17.53 1 4 4 12 6.086E7 7.23 17.53 4 5 731.78 17.53 4 7 365 39.0 4.61 HVO_0600 ACT domain protein 17.51 1 3 3 9 3.120E7 4.92 17.51 3 4 431.48 17.51 3 5 177 19.2 4.44 HVO_1723 DNA repair helicase Rad25 17.41 1 9 9 23 3.270E7 16.99 15.83 8 12 1068.30 14.10 8 11 695 76.8 4.69 HVO_B0127 oxidoreductase (luciferase family protein) 17.35 1 4 4 16 4.157E7 14.92 17.35 4 8 892.39 17.35 4 8 317 35.7 4.60 HVO_1593 PAC2 family protein 17.34 1 3 3 8 3.369E7 7.52 17.34 3 4 499.48 17.34 3 4 248 26.6 4.46 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 17.30 1 3 3 9 2.010E7 4.67 17.30 3 4 275.74 17.30 3 5 237 26.2 4.70 HVO_2914 conserved hypothetical protein 17.14 1 2 2 2 8.771E6 95.94 17.14 2 2 140 16.1 4.61 HVO_C0042 helicase domain protein 17.03 1 18 18 52 8.688E7 54.40 16.33 17 26 3228.97 16.17 17 26 1274 144.4 4.67 HVO_0001 Orc1-type DNA replication protein 17.02 1 8 9 31 2.616E7 23.58 15.96 8 14 1847.00 17.02 9 17 564 62.1 4.39 HVO_2227 siroheme decarboxylase AhbA 17.00 1 4 4 12 3.752E7 12.71 17.00 4 6 712.60 17.00 4 6 347 39.1 4.69 HVO_0469 AstE family protein 16.98 1 4 4 12 6.796E7 12.09 16.98 4 6 933.35 16.98 4 6 318 33.9 5.85 HVO_A0486 hydrogenase expression/formation protein 16.96 1 3 3 12 3.221E7 7.60 16.96 3 6 668.48 16.96 3 6 336 33.8 4.06 HVO_0304 electron transfer flavoprotein alpha subunit 16.72 1 3 3 13 3.127E7 17.93 13.56 2 5 1372.95 16.72 3 8 317 33.5 4.18 HVO_0868 NAD-dependent epimerase/dehydratase 16.72 1 5 5 15 6.511E7 6.00 16.72 5 7 725.93 16.72 5 8 329 36.1 4.55 HVO_1918 probable metallo-beta-lactamase family hydrolase 16.56 1 2 2 4 2.001E7 6.78 16.56 2 2 314.37 16.56 2 2 302 34.0 4.55 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 16.50 1 5 5 13 2.819E7 10.78 10.84 4 6 740.68 16.50 5 7 406 45.5 5.08 HVO_B0055 conserved hypothetical protein 16.44 1 5 5 21 1.172E8 13.06 16.44 5 10 1116.15 16.44 5 11 225 23.9 4.69 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 16.40 1 5 5 14 3.434E7 11.04 16.40 5 7 695.00 16.40 5 7 378 39.8 4.45 HVO_1344 SBDS family protein 16.39 1 3 3 15 2.296E7 17.00 16.39 3 7 920.59 16.39 3 8 238 26.5 4.51 HVO_2761 mevalonate kinase 16.35 1 4 4 9 1.987E7 4.68 16.35 4 5 377.46 9.26 3 4 367 38.2 4.31 HVO_B0117 conserved hypothetical protein 16.35 1 3 3 10 3.045E7 7.43 16.35 3 5 578.58 16.35 3 5 208 23.3 4.58 HVO_2072 S-layer glycoprotein 16.32 1 6 6 88 8.713E8 103.03 16.32 6 45 4763.85 16.32 6 43 827 85.1 3.65 HVO_0879 DUF371 family protein 16.31 1 2 2 11 1.620E7 6.02 16.31 2 5 402.35 16.31 2 6 141 15.3 4.65 HVO_A0485 aminotransferase class V 16.24 1 4 4 13 7.591E7 11.87 11.97 3 6 977.42 16.24 4 7 351 37.3 4.26 HVO_1356 sensor box histidine kinase 16.18 1 6 6 18 5.959E7 9.90 16.18 6 9 893.12 16.18 6 9 550 61.1 4.60 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 16.03 1 16 16 42 7.405E7 33.29 13.26 13 20 2196.39 16.03 16 22 1335 150.5 4.60 HVO_0760 "probable glycosyltransferase, type 2" 15.76 1 4 4 12 2.193E7 5.38 15.76 4 7 512.93 8.70 3 5 368 40.7 4.82 HVO_A0092 acyl-CoA dehydrogenase 15.75 1 5 5 14 2.054E7 11.34 15.75 5 7 666.75 15.75 5 7 381 42.2 4.83 HVO_2564 50S ribosomal protein L3 15.68 1 4 4 9 1.430E7 8.05 15.68 4 4 591.75 15.68 4 5 338 37.2 6.68 HVO_2888 homolog to elongator complex protein ELP3 15.64 1 8 8 26 1.075E8 14.95 15.64 8 13 1361.18 15.64 8 13 550 62.6 5.01 HVO_0044 acetylglutamate kinase 15.60 1 4 4 11 1.162E8 13.07 15.60 4 6 787.63 11.93 3 5 327 33.2 4.49 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 15.60 1 3 3 8 1.855E7 4.20 10.40 2 4 324.78 15.60 3 4 327 36.2 4.63 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 15.54 1 4 5 13 2.336E7 13.69 15.54 5 7 632.46 13.99 4 6 386 41.3 4.46 HVO_0569 RIO-type serine/threonine protein kinase 15.51 1 3 3 8 1.258E7 5.28 15.51 3 4 482.72 15.51 3 4 303 34.4 4.94 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 15.41 1 6 6 50 7.730E8 51.83 15.41 6 25 3312.34 15.41 6 25 357 40.3 4.40 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 15.38 1 5 5 12 4.556E7 10.44 13.15 4 5 598.46 15.38 5 7 403 41.1 4.73 HVO_2918 thymidylate synthase 15.36 1 3 3 12 5.947E7 7.60 15.36 3 6 699.95 15.36 3 6 332 37.5 4.61 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 15.35 1 7 7 24 5.775E7 22.67 15.35 7 12 1668.03 15.35 7 12 658 72.1 4.70 HVO_1437 conserved hypothetical protein 15.27 1 3 3 6 2.381E7 4.80 15.27 3 3 333.37 15.27 3 3 203 22.3 4.94 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 15.27 1 12 12 27 5.252E7 14.40 12.84 10 13 1531.69 14.05 11 14 740 85.6 4.70 HVO_0220 ATP-dependent DNA helicase MCM 15.24 1 9 9 25 2.783E7 15.01 15.24 9 13 1152.51 14.39 8 12 702 78.8 4.73 HVO_2554 50S ribosomal protein L14 15.15 1 2 2 4 5.045E7 3.73 15.15 2 2 224.84 15.15 2 2 132 14.2 9.76 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 15.14 1 12 12 35 5.242E7 28.09 15.14 12 17 2136.70 15.14 12 18 898 97.7 4.45 HVO_2018 conserved hypothetical protein 15.13 1 2 2 2 8.935E6 93.29 15.13 2 2 119 13.4 4.73 HVO_A0328 2-keto-3-deoxygluconate kinase 15.09 1 3 4 10 1.058E8 5.21 15.09 4 5 416.24 15.09 4 5 318 34.0 4.60 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 15.07 1 4 4 7 2.953E7 0.00 8.90 3 4 193.50 13.24 3 3 438 46.4 4.58 HVO_0733 transcription initiation factor TFB 15.03 1 1 5 15 1.752E8 12.95 11.35 4 7 1033.89 15.03 5 8 326 37.2 6.00 HVO_2873 flap endonuclease Fen1 15.03 1 3 3 10 3.991E7 12.37 15.03 3 5 840.54 15.03 3 5 326 36.4 4.40 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 14.77 1 3 3 6 4.963E7 3.29 14.77 3 3 447.92 14.77 3 3 237 25.4 4.46 HVO_0787 indole-3-glycerol-phosphate synthase 14.74 1 3 3 6 1.445E7 0.00 14.74 3 3 165.00 14.74 3 3 251 26.7 4.44 HVO_B0143 receiver/sensor box histidine kinase 14.74 1 7 7 19 3.274E7 17.27 12.56 6 9 1203.06 14.74 7 10 597 66.0 4.41 HVO_2665 HpcH/HpaI aldolase family protein 14.72 1 4 4 13 3.927E7 10.49 12.45 3 6 678.19 14.72 4 7 265 28.3 4.50 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 14.65 1 5 5 30 1.655E8 17.28 14.65 5 15 1624.43 14.65 5 15 430 44.2 4.37 HVO_2636 PspA domain protein 14.49 1 4 4 10 9.952E6 9.46 14.49 4 5 738.68 14.49 4 5 276 30.9 4.61 HVO_1710 alpha amylase 14.48 1 11 11 33 8.787E7 13.06 13.74 10 16 1732.24 14.48 11 17 677 75.0 4.45 HVO_2998 homoserine O-acetyltransferase 14.46 1 3 3 8 1.570E7 8.92 14.46 3 4 633.14 14.46 3 4 415 44.8 4.69 HVO_2373 30S ribosomal protein S8e 14.40 1 2 2 4 2.937E7 1.81 14.40 2 2 193.13 14.40 2 2 125 13.6 10.48 HVO_B0026 probable oxidoreductase (short-chain dehydrogenase family) 14.40 1 2 2 8 3.036E7 4.15 14.40 2 4 237.16 14.40 2 4 257 26.7 4.55 HVO_1375 O-succinylbenzoic acid--CoA ligase 14.33 1 7 7 22 4.444E7 21.20 14.33 7 11 1026.03 14.33 7 11 614 64.7 4.28 HVO_1249 conserved hypothetical protein 14.08 1 2 2 2 2.691E7 0.00 14.08 2 2 142 16.4 5.20 HVO_B0154 receiver/sensor box histidine kinase 14.07 1 14 14 44 4.176E7 36.15 14.07 14 23 2288.07 13.45 13 21 1301 144.1 4.39 HVO_1413 probable NADH dehydrogenase 14.06 1 4 4 10 1.685E7 7.41 14.06 4 6 371.99 14.06 4 4 377 39.7 4.67 HVO_2605 MiaB-like tRNA modifying enzyme 13.99 1 5 5 15 2.129E7 7.09 10.96 4 7 717.46 13.99 5 8 429 47.4 5.03 HVO_2160 conserved hypothetical protein 13.96 1 19 19 145 8.213E8 180.54 13.96 19 73 13045.14 13.96 19 72 2257 232.7 3.92 HVO_1615 conserved hypothetical protein 13.94 1 2 2 3 1.798E7 173.41 13.94 2 3 251 28.4 4.59 HVO_2510 GNAT family acetyltransferase 13.82 1 3 3 10 1.629E7 9.63 13.82 3 5 633.41 13.82 3 5 304 33.7 4.49 HVO_1419 HTH-10 family transcription regulator 13.78 1 3 3 5 1.657E7 2.88 8.89 2 2 370.08 13.78 3 3 225 25.2 4.77 HVO_0431 HAD superfamily hydrolase 13.73 1 4 4 16 3.216E7 10.43 13.73 4 8 789.41 13.73 4 8 284 30.4 4.26 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 8 9.726E7 2.39 13.66 2 4 472.01 13.66 2 4 183 20.0 4.21 HVO_0194 Orc1-type DNA replication protein 13.64 1 5 5 16 3.435E7 11.14 13.64 5 8 646.86 13.64 5 8 374 42.2 4.94 HVO_2456 anthranilate phosphoribosyltransferase 13.60 1 2 2 6 1.450E8 7.73 13.60 2 3 353.73 13.60 2 3 331 33.8 4.35 HVO_2908 dihydropteroate synthase 13.46 1 4 4 10 3.661E7 5.78 13.46 4 5 461.22 13.46 4 5 379 40.8 4.53 HVO_2503 kynureninase 13.41 1 5 5 12 4.449E7 4.45 13.41 5 6 462.27 13.41 5 6 425 46.0 4.54 HVO_0712 shikimate dehydrogenase (nonfunctional) 13.38 1 2 2 6 2.650E7 5.48 13.38 2 3 354.29 13.38 2 3 269 27.7 4.65 HVO_1407 HTH domain protein 13.33 1 2 2 8 2.870E7 5.05 13.33 2 4 471.11 13.33 2 4 225 24.9 4.45 HVO_A0150 TrmB family transcription regulator 13.28 1 5 5 14 6.950E7 8.74 13.28 5 7 646.29 13.28 5 7 354 39.0 4.63 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 13.24 1 5 5 18 1.027E8 21.61 13.24 5 9 1342.85 13.24 5 9 423 43.9 4.31 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 13.24 1 3 3 9 1.040E7 4.78 13.24 3 5 282.68 13.24 3 4 287 31.8 4.93 HVO_0670 glutathione S-transferase 13.19 1 3 3 9 2.462E7 2.94 9.51 2 4 262.34 13.19 3 5 326 38.1 4.56 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 13.16 1 4 4 11 6.033E7 5.44 9.62 3 4 733.86 13.16 4 7 395 42.4 4.54 HVO_1323 "shikimate kinase, archaeal-type" 13.15 1 3 3 18 1.192E8 17.98 13.15 3 9 1462.17 13.15 3 9 289 29.5 4.30 HVO_2255 conserved hypothetical protein 13.14 1 2 2 5 2.363E7 2.53 13.14 2 2 341.07 13.14 2 3 236 27.7 5.60 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 13.12 1 4 4 12 3.922E7 11.06 13.12 4 6 842.28 13.12 4 6 442 46.9 4.58 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 13.11 1 3 3 10 3.090E7 11.65 9.84 2 5 515.59 13.11 3 5 305 34.1 4.91 HVO_1354 DNA mismatch repair protein MutS 13.10 1 7 7 16 2.869E7 7.63 13.10 7 8 689.07 13.10 7 8 580 62.1 4.56 HVO_0190 TIGR00268 family protein 13.09 1 3 3 10 1.851E7 2.76 13.09 3 5 377.87 13.09 3 5 298 32.5 4.60 HVO_1073 ThiJ/PfpI family protein 12.95 1 2 2 8 4.804E7 5.51 12.95 2 4 311.76 12.95 2 4 224 23.9 4.12 HVO_0120 signal recognition particle receptor FtsY 12.94 1 5 5 14 2.436E7 12.24 12.94 5 7 997.54 12.94 5 7 456 48.2 4.17 HVO_1077 diphthamide biosynthesis protein Dph6 12.92 1 2 2 6 2.411E7 1.72 12.92 2 3 242.26 12.92 2 3 240 26.0 4.15 HVO_1055 TrkA domain protein 12.83 1 3 3 6 7.015E6 3.93 12.83 3 3 240.36 12.83 3 3 226 24.4 4.39 HVO_B0066 Lrp/AsnC family transcription regulator 12.80 1 2 2 6 1.356E7 8.33 12.80 2 3 422.74 12.80 2 3 164 18.5 4.41 HVO_1446 "fructose-1,6-bisphosphatase" 12.79 1 2 2 4 1.228E7 4.76 12.79 2 2 254.05 12.79 2 2 297 31.6 4.45 HVO_1914 acetyl-CoA C-acyltransferase 12.73 1 5 5 13 2.136E8 10.72 7.69 3 5 945.66 12.73 5 8 377 39.9 4.41 HVO_2581 quinolinate synthase A 12.73 1 4 4 12 5.215E7 2.13 12.73 4 6 353.74 12.73 4 6 385 42.0 4.41 HVO_A0635 probable cysteine desulfurase 12.67 1 2 3 8 4.457E7 3.40 12.67 3 4 357.31 10.78 2 4 371 40.4 4.53 HVO_1268 conserved hypothetical protein 12.66 1 2 2 6 2.348E7 7.16 12.66 2 3 482.18 12.66 2 3 237 26.4 5.21 HVO_A0498 conserved hypothetical protein 12.66 1 4 4 10 2.463E7 0.00 12.66 4 5 372.58 12.66 4 5 379 42.7 4.55 HVO_2004 serine O-acetyltransferase 12.54 1 2 3 10 1.765E8 6.49 12.54 3 5 514.47 12.54 3 5 287 31.9 5.21 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 12.50 1 0 6 19 6.310E8 15.18 10.75 5 9 1089.31 12.50 6 10 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 12.50 1 0 6 19 6.310E8 15.18 10.75 5 9 1089.31 12.50 6 10 400 44.1 5.14 HVO_1594 tRNA/rRNA cytosine-C5-methylase 12.46 1 3 3 9 7.056E7 8.86 9.27 2 4 632.59 12.46 3 5 313 34.6 4.69 HVO_A0003 ParA domain protein 12.41 1 3 3 8 1.314E7 6.73 12.41 3 4 387.67 12.41 3 4 274 30.3 4.53 HVO_2158 malic enzyme (NADP) 12.38 1 2 6 22 1.098E8 16.37 7.99 4 10 1164.93 12.38 6 12 751 81.4 4.55 HVO_0145 replication factor C small subunit 12.32 1 3 3 6 1.065E7 3.89 12.32 3 3 236.99 12.32 3 3 341 37.8 4.93 HVO_0326 CTP-dependent riboflavin kinase 12.24 1 2 2 6 2.908E7 9.55 12.24 2 3 496.36 12.24 2 3 237 25.9 4.55 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 12.24 1 3 3 5 1.241E7 2.10 6.99 2 2 200.23 12.24 3 3 286 30.8 4.46 HVO_2485 biotin--[acetyl-CoA-carboxylase] ligase 11.98 1 2 2 4 1.864E7 7.38 11.98 2 2 267.43 11.98 2 2 334 35.7 4.75 HVO_0103 conserved hypothetical protein 11.94 1 2 2 6 1.351E7 2.07 11.94 2 3 328.30 11.94 2 3 201 22.4 4.21 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 11.87 1 4 4 12 1.535E7 5.95 11.87 4 6 600.74 11.87 4 6 379 41.7 4.83 HVO_2932 GTP-binding protein 11.87 1 4 4 12 3.996E7 4.09 11.87 4 7 355.64 11.87 4 5 396 43.5 4.51 HVO_2891 thymidine kinase 11.79 1 2 2 10 2.008E7 7.22 11.79 2 5 519.92 11.79 2 5 195 21.4 4.63 HVO_A0156 acyl-CoA synthetase 11.75 1 2 6 14 8.682E7 7.40 11.75 6 8 672.35 10.24 5 6 664 74.0 4.40 HVO_0228 ParA domain protein 11.74 1 2 2 3 1.167E8 356.51 11.74 2 3 247 24.6 4.16 HVO_2501 alpha/beta hydrolase fold protein 11.71 1 3 3 10 1.964E7 11.53 11.71 3 5 674.58 11.71 3 5 316 35.3 5.72 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 11.66 1 4 4 8 1.281E7 1.82 11.66 4 4 282.69 11.66 4 4 386 40.0 4.68 HVO_A0230 peptide methionine sulfoxide reductase MsrA (S-form specific) 11.64 1 2 2 3 3.571E7 172.97 11.64 2 3 189 21.0 4.27 HVO_2965 phosphoserine phosphatase 11.63 1 2 2 6 1.857E7 3.54 11.63 2 3 433.28 11.63 2 3 215 23.2 4.51 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 11.62 1 0 7 25 6.310E8 24.33 11.62 7 13 1547.68 8.99 6 12 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 11.62 1 0 7 25 6.310E8 24.33 11.62 7 13 1547.68 8.99 6 12 456 49.2 4.77 HVO_2941 nonhistone chromosomal protein 11.54 1 2 2 4 1.439E6 2.17 11.54 2 2 127.38 11.54 2 2 104 11.6 5.60 HVO_1150 IS200-type transposase 11.54 1 2 2 5 2.196E7 443.17 11.54 2 5 130 14.7 5.49 HVO_1725 Orc1-type DNA replication protein 11.47 1 4 5 11 3.461E7 7.13 9.98 4 5 601.35 11.47 5 6 401 44.5 5.19 HVO_B0182 deoxyhypusine synthase 11.42 1 3 3 12 4.087E7 10.07 11.42 3 6 671.46 11.42 3 6 324 35.6 4.30 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 11.37 1 4 4 18 1.679E8 12.69 11.37 4 9 922.49 11.37 4 9 299 32.0 4.53 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 11.33 1 3 3 12 1.395E7 10.34 11.33 3 6 750.08 11.33 3 6 406 43.1 4.60 HVO_2640 conserved hypothetical protein 11.33 1 2 2 2 0.000E0 162.75 11.33 2 2 309 33.9 4.56 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 11.22 1 2 2 6 3.815E7 2.10 11.22 2 3 198.28 11.22 2 3 294 32.5 4.75 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 11.20 1 2 2 6 1.922E7 8.12 11.20 2 3 424.00 11.20 2 3 241 26.1 4.58 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 11.19 1 3 3 8 3.135E7 6.19 11.19 3 4 399.33 11.19 3 4 420 45.0 4.86 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 11.15 1 3 3 12 1.037E8 18.97 11.15 3 6 1203.15 11.15 3 6 574 62.8 4.17 HVO_0069 sulfatase 11.07 1 5 5 13 2.264E7 4.44 7.38 4 6 531.90 11.07 5 7 515 57.4 4.35 HVO_A0551 acyl-CoA synthetase 10.97 1 5 5 18 1.777E7 17.48 10.97 5 9 1053.54 10.97 5 9 538 59.6 4.65 HVO_0156 "tRNA (guanine(10),N(2))-dimethyltransferase" 10.90 1 3 3 10 1.169E7 10.20 10.90 3 5 704.19 10.90 3 5 321 34.2 5.25 HVO_1470 isochorismate synthase 10.84 1 3 3 7 9.446E6 7.74 6.09 2 3 470.38 10.84 3 4 443 47.7 4.56 HVO_2131 "fructose-1,6-bisphosphatase" 10.73 1 2 2 4 4.352E6 5.04 10.73 2 2 266.71 10.73 2 2 289 31.3 4.48 HVO_2955 DEAD/DEAH box helicase 10.65 1 6 6 11 2.689E7 7.36 7.19 4 4 522.73 10.65 6 7 779 85.8 4.94 HVO_B0256 aldehyde ferredoxin oxidoreductase 10.63 1 4 4 12 3.988E7 15.04 10.63 4 6 843.28 10.63 4 6 555 59.9 4.55 HVO_3000 DNA ligase (NAD) 10.59 1 6 6 13 8.914E7 11.63 10.59 6 7 830.41 9.01 5 6 699 75.8 4.50 HVO_1008 GFO family oxidoreductase 10.54 1 3 3 10 2.623E7 7.98 10.54 3 5 561.41 10.54 3 5 332 36.0 4.72 HVO_1228 halocyanin 10.48 1 8 8 30 5.306E7 34.70 10.48 8 15 2059.36 10.48 8 15 821 83.7 4.17 HVO_1380 methylmalonyl-CoA mutase subunit A 10.39 1 3 3 10 1.973E7 6.72 10.39 3 5 412.05 10.39 3 5 558 61.9 4.41 HVO_1704 homolog to arabinopyranose mutase 10.39 1 3 3 10 2.493E7 12.90 10.39 3 5 766.76 10.39 3 5 385 43.4 4.23 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 10.33 1 3 3 10 4.525E7 8.15 10.33 3 5 731.41 10.33 3 5 329 36.3 4.49 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 10.33 1 2 2 4 2.201E7 188.82 10.33 2 4 184 20.0 4.75 HVO_2421 probable DNA-binding protein 10.21 1 2 2 4 2.648E7 2.17 10.21 2 2 150.14 10.21 2 2 235 25.8 4.89 HVO_B0058 precorrin-3B C17-methyltransferase 10.20 1 2 2 4 2.297E7 4.72 10.20 2 2 360.43 10.20 2 2 294 31.8 4.40 HVO_0522 HdaI-type histone deacetylase 10.09 1 2 2 6 1.205E7 9.96 10.09 2 3 534.62 10.09 2 3 337 36.3 4.45 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 10.09 1 4 4 6 3.341E7 6.21 7.42 3 3 325.45 8.31 3 3 337 35.9 4.39 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 10 6.229E7 4.19 10.00 2 5 497.57 10.00 2 5 190 21.0 4.74 HVO_A0476 conserved hypothetical protein 9.97 1 3 3 8 1.367E7 4.88 9.97 3 4 437.58 9.97 3 4 331 35.4 4.26 HVO_2321 bacterial-type DNA primase DnaG 9.96 1 4 4 12 2.439E7 4.84 9.96 4 6 453.16 9.96 4 6 472 49.4 4.36 HVO_2248 conserved hypothetical protein 9.96 1 2 2 6 8.434E6 0.00 9.96 2 3 136.52 9.96 2 3 271 31.3 4.77 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 9.92 1 2 2 16 2.575E8 11.60 9.92 2 8 954.79 9.92 2 8 363 39.7 4.25 HVO_2614 uridine phosphorylase 9.92 1 3 3 14 3.346E8 11.28 9.92 3 7 871.77 9.92 3 7 242 25.8 4.30 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 9.90 1 6 6 18 3.010E7 11.31 7.76 5 8 913.49 9.90 6 10 838 89.1 4.65 HVO_1058 TrkA domain protein 9.89 1 3 3 9 4.467E7 6.52 9.89 3 4 306.07 9.89 3 5 445 47.7 4.35 HVO_0470 threonine synthase 9.81 1 3 3 3 1.793E7 2.06 9.81 3 3 367 39.2 4.59 HVO_1501 DeoR family transcription regulator GlpR 9.80 1 2 2 2 2.323E7 182.88 9.80 2 2 255 28.0 4.97 4504911 keratin 13 isoform b [Homo sapiens] 9.76 1 0 5 17 1.424E8 21.68 9.76 5 9 1144.81 6.90 4 8 420 45.8 4.88 HVO_0019 probable S-adenosylmethionine-dependent methyltransferase (homolog to 24-sterol C-methyltransferase) 9.73 1 2 2 11 3.450E7 10.48 9.73 2 4 634.46 9.73 2 7 226 25.6 4.64 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 9.72 1 3 3 16 6.926E7 17.31 9.72 3 8 977.40 9.72 3 8 360 39.5 4.31 HVO_0561 50S ribosomal protein L15e 9.69 1 1 2 6 9.181E6 6.68 9.69 2 3 470.46 9.69 2 3 196 22.5 11.15 HVO_0135 RIO-type serine/threonine protein kinase 9.66 1 3 3 8 2.098E7 5.31 7.24 2 3 643.16 9.66 3 5 290 33.0 4.81 HVO_0476 conserved hypothetical protein 9.63 1 2 2 8 1.492E7 8.97 9.63 2 4 575.74 9.63 2 4 218 23.8 4.60 HVO_1357 receiver/bat box HTH-10 family transcription regulator 9.62 1 4 4 11 3.048E7 7.26 9.62 4 6 422.64 7.22 3 5 582 62.7 4.40 HVO_1936 F420-0:gamma-glutamyl ligase 9.56 1 2 2 4 1.781E7 4.94 9.56 2 2 275.44 9.56 2 2 251 27.4 4.68 HVO_A0452 UspA domain protein 9.56 1 2 2 4 8.904E6 3.16 9.56 2 2 244.67 9.56 2 2 293 31.3 4.63 HVO_0768 radical SAM domain protein 9.56 1 2 2 3 1.823E7 110.51 9.56 2 3 565 62.0 4.84 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 9.50 1 4 4 10 2.815E7 7.99 9.50 4 5 478.57 9.50 4 5 516 56.7 4.89 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 9.48 1 3 3 5 8.488E6 2.02 9.48 3 3 206.05 6.73 2 2 401 43.1 4.60 HVO_1140 acyl-CoA dehydrogenase 9.47 1 3 3 6 6.767E6 4.92 9.47 3 3 329.23 9.47 3 3 380 41.2 4.55 HVO_1995 conserved hypothetical protein 9.47 1 2 2 8 1.370E7 8.12 9.47 2 4 481.05 9.47 2 4 243 26.5 4.39 HVO_B0200 malate synthase 9.40 1 2 2 6 5.741E7 7.99 9.40 2 3 459.26 9.40 2 3 436 48.3 4.30 HVO_0675 pantoate kinase 9.39 1 2 2 2 1.393E7 146.83 9.39 2 2 277 27.8 4.54 HVO_2349 TrmB family transcription regulator 9.36 1 2 2 4 1.268E7 0.00 9.36 2 2 68.74 9.36 2 2 267 29.3 4.44 HVO_2573 probable methenyltetrahydrofolate cyclohydrolase 9.35 1 2 2 6 3.673E7 9.80 9.35 2 3 714.70 9.35 2 3 310 32.7 3.92 HVO_C0067 FAD-dependent oxidoreductase 9.34 1 4 4 10 3.517E7 11.63 9.34 4 5 779.28 9.34 4 5 396 42.7 4.30 HVO_0558 SAMP-activating enzyme E1 9.26 1 2 2 6 1.866E7 5.42 9.26 2 3 470.96 9.26 2 3 270 28.7 4.35 HVO_0848 endonuclease III 9.25 1 2 2 3 9.640E6 2.24 9.25 2 3 227 25.5 4.55 HVO_1895 KEOPS complex subunit Kae1/Bud32 9.24 1 3 3 10 4.797E7 15.28 9.24 3 5 796.69 9.24 3 5 552 59.0 5.07 HVO_0077 uroporphyrin-III C-methyltransferase 9.22 1 2 3 7 8.215E6 1.62 9.22 3 4 140.84 7.17 2 3 293 30.5 4.50 HVO_A0257 Orc1-type DNA replication protein 9.18 1 4 4 9 8.946E6 6.71 7.06 3 4 602.47 9.18 4 5 425 48.0 4.94 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 9.15 1 2 2 6 2.434E7 3.38 9.15 2 3 285.57 9.15 2 3 328 36.1 4.67 HVO_2311 glutamyl-tRNA reductase 9.11 1 3 3 9 8.168E6 6.95 9.11 3 5 366.38 4.77 2 4 461 49.2 4.54 HVO_A0158 acyl-CoA synthetase 9.08 1 1 3 5 4.239E7 2.59 3.23 2 3 184.46 7.54 2 2 650 71.2 4.63 HVO_1374 acyl-CoA synthetase 9.04 1 4 4 14 3.661E7 12.05 9.04 4 7 974.76 9.04 4 7 553 61.1 4.50 HVO_2880 probable peptide chain release factor pelota 8.99 1 3 3 11 4.592E7 4.65 8.99 3 6 487.86 8.99 3 5 356 39.3 4.63 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 8.95 1 0 5 17 1.424E8 21.68 8.95 5 9 1144.81 6.33 4 8 458 49.6 4.96 HVO_1387 enoyl-CoA hydratase 8.95 1 2 2 4 8.754E6 0.00 8.95 2 2 95.92 8.95 2 2 257 27.5 4.51 HVO_B0101 IclR family transcription regulator 8.95 1 2 2 6 1.156E7 2.14 8.95 2 3 261.34 8.95 2 3 257 28.6 5.02 HVO_2297 deoxyhypusine synthase 8.91 1 2 2 6 9.396E7 0.00 8.91 2 3 136.40 8.91 2 3 359 38.6 4.59 HVO_2187 CHP01210 family protein 8.89 1 3 3 10 1.645E7 6.92 8.89 3 5 672.98 8.89 3 5 360 40.0 4.58 HVO_1340 "probable glycosyltransferase, type 1" 8.80 1 3 3 8 5.497E7 4.33 8.80 3 4 457.91 8.80 3 4 375 41.0 4.42 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 8.66 1 4 4 8 1.984E7 6.90 8.66 4 4 326.91 8.66 4 4 439 47.2 4.59 HVO_1928 5-formyltetrahydrofolate cyclo-ligase 8.64 1 2 2 4 1.127E8 2.06 8.64 2 2 192.09 8.64 2 2 243 26.5 4.69 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 8.63 1 3 3 6 1.707E7 4.46 8.63 3 3 324.67 8.63 3 3 475 49.3 4.49 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 8.57 1 2 2 6 2.243E7 6.53 8.57 2 3 337.09 8.57 2 3 280 30.0 4.92 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 8.51 1 3 3 9 3.793E7 3.93 8.51 3 4 342.22 8.51 3 5 388 41.9 4.35 HVO_2070 conserved hypothetical protein 8.46 1 4 4 10 1.585E7 9.39 8.46 4 5 762.98 8.46 4 5 544 58.1 4.50 31074633 keratin 6L [Homo sapiens] 8.41 1 0 5 20 3.104E8 21.72 8.41 5 10 1384.63 8.41 5 10 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 8.41 1 0 5 20 3.104E8 21.72 8.41 5 10 1384.63 8.41 5 10 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 8.41 1 0 5 20 3.104E8 21.72 8.41 5 10 1384.63 8.41 5 10 535 57.7 7.20 HVO_1235 creatininase 8.33 1 2 2 6 2.653E7 2.08 8.33 2 3 192.76 8.33 2 3 264 29.2 4.84 HVO_B0038A D-xylonate dehydratase 8.25 1 0 3 19 2.012E8 10.36 8.25 3 10 914.27 4.61 2 9 412 45.5 4.55 HVO_1565 DNA ligase (ATP) 8.21 1 4 4 9 1.882E7 9.53 6.67 3 4 575.76 8.21 4 5 585 62.7 4.44 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 8.13 1 3 3 9 3.556E7 8.63 6.10 2 4 446.42 8.13 3 5 492 52.1 4.83 HVO_1668 gamma-glutamylcysteine synthetase 8.10 1 3 3 8 4.620E6 7.95 8.10 3 4 448.20 8.10 3 4 358 39.9 4.72 HVO_1424 conserved hypothetical protein 8.08 1 3 3 10 1.408E7 5.86 8.08 3 5 328.97 8.08 3 5 359 40.9 4.60 HVO_1117 HTH-10 family transcription regulator 7.98 1 2 2 3 6.201E6 416.68 7.98 2 3 213 23.3 4.56 HVO_A0562 urocanate hydratase 7.90 1 3 3 10 1.602E7 9.12 7.90 3 5 591.22 7.90 3 5 620 67.9 4.70 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 7.76 1 2 2 5 5.960E7 0.00 7.76 2 2 155.04 7.76 2 3 348 36.7 4.69 HVO_0029 UvrABC system protein B 7.74 1 4 4 10 1.782E7 6.38 7.74 4 5 617.21 7.74 4 5 698 79.0 4.45 HVO_A0018 IS1341-type transposase 7.67 1 2 2 2 6.720E7 0.00 7.67 2 2 404 45.2 5.35 4504919 keratin 8 [Homo sapiens] 7.66 1 0 6 49 3.157E8 38.02 7.66 6 24 2722.53 7.66 6 25 483 53.7 5.59 HVO_0477 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 7.52 1 2 2 6 8.363E7 4.27 7.52 2 3 307.98 7.52 2 3 319 33.4 4.18 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 7.47 1 3 3 9 2.929E7 2.10 5.19 2 4 352.33 7.47 3 5 482 50.6 4.31 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 7.40 1 2 2 3 1.032E7 185.23 7.40 2 3 446 47.9 4.39 HVO_0689 chromosome segregation protein Smc 7.34 1 8 8 26 2.858E7 14.31 7.34 8 13 1080.73 6.69 7 13 1240 138.1 4.39 HVO_0322 MinD/ParA domain protein 7.23 1 3 3 8 6.800E7 5.18 7.23 3 4 425.28 7.23 3 4 581 58.8 3.70 HVO_1047 NADPH:quinone reductase 7.12 1 2 2 6 1.110E7 5.02 7.12 2 3 325.47 7.12 2 3 323 33.8 4.27 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 7.07 1 3 3 6 1.010E7 3.46 7.07 3 3 300.06 7.07 3 3 410 46.0 4.89 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 6 2.953E7 8.77 7.07 2 3 567.16 7.07 2 3 297 32.3 3.98 HVO_A0119 cyclase family protein 7.05 1 0 2 6 4.301E7 0.00 7.05 2 3 204.40 7.05 2 3 227 25.5 4.59 HVO_A0415 cyclase family protein 7.05 1 0 2 6 4.301E7 0.00 7.05 2 3 204.40 7.05 2 3 227 25.5 4.59 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 14 4.405E8 3.95 6.94 3 7 679.95 6.94 3 7 389 40.8 4.89 HVO_1879 enoyl-CoA hydratase 6.93 1 2 2 4 2.267E8 0.00 6.93 2 2 141.95 6.93 2 2 231 24.3 5.21 31559823 keratin 25D [Homo sapiens] 6.90 1 0 4 14 3.696E8 10.10 6.90 4 7 786.74 6.90 4 7 464 50.6 5.47 HVO_A0550 receiver/sensor box histidine kinase 6.89 1 6 6 21 1.248E7 16.69 6.89 6 11 1190.84 6.89 6 10 885 95.9 4.46 HVO_1540 glycerol-3-phosphate dehydrogenase subunit C 6.88 1 3 3 3 6.647E6 178.38 6.88 3 3 436 48.6 4.61 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 6.81 1 2 2 3 1.422E7 260.00 6.81 2 3 323 34.9 5.24 HVO_2073 TrmB family transcription regulator 6.77 1 2 2 2 9.923E6 161.62 6.77 2 2 251 27.5 4.72 HVO_1861 thiamine-monophosphate kinase 6.73 1 2 2 6 1.558E7 6.81 6.73 2 3 323.09 6.73 2 3 297 30.8 4.32 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 6.67 1 2 2 6 3.235E7 1.96 6.67 2 3 360.87 6.67 2 3 345 37.0 3.95 HVO_0968 NADH dehydrogenase-like complex subunit CD 6.56 1 0 4 12 8.963E7 13.43 6.21 3 5 846.63 6.56 4 7 564 63.3 4.60 HVO_0824 "probable glycosyltransferase, type 1" 6.53 1 2 2 3 4.150E6 2.15 6.53 2 3 352 39.6 5.08 HVO_1864 molybdopterin synthase catalytic subunit 6.51 1 2 2 6 2.764E7 0.00 6.51 2 3 138.06 6.51 2 3 261 27.9 4.41 HVO_A0093 IclR family transcription regulator 6.50 1 2 2 4 6.058E6 0.00 6.50 2 2 114.48 6.50 2 2 246 27.5 5.15 HVO_B0233 alpha-L-arabinofuranosidase 6.46 1 2 2 6 2.584E8 4.73 6.46 2 3 309.93 6.46 2 3 511 57.5 4.39 HVO_0662 HTH domain protein / thiamine-phosphate synthase 6.35 1 2 2 6 1.725E7 1.74 6.35 2 3 220.54 6.35 2 3 299 31.9 4.44 HVO_0687 M20 family amidohydrolase 6.08 1 2 2 6 2.060E7 5.28 6.08 2 3 288.90 6.08 2 3 444 47.5 4.58 HVO_1676 transcription initiation factor TFB 6.02 1 0 2 6 6.760E7 4.12 6.02 2 3 352.67 6.02 2 3 332 37.3 5.49 HVO_2058 NAD-dependent epimerase/dehydratase (homolog to dTDP-4-dehydrorhamnose reductase) 6.00 1 2 2 4 5.836E7 1.78 6.00 2 2 203.73 6.00 2 2 300 32.0 4.22 HVO_1681 DNA N-glycosylase 5.92 1 2 2 3 2.042E7 404.16 5.92 2 3 304 34.2 4.63 HVO_B0054 sirohydrochlorin cobaltochelatase 5.91 1 2 2 3 6.313E6 159.76 5.91 2 3 406 44.1 4.72 HVO_1579 uridine phosphorylase 5.88 1 2 2 6 5.902E7 4.15 5.88 2 3 307.55 5.88 2 3 272 29.0 4.64 18031720 keratin protein K6irs [Homo sapiens] 5.49 1 0 3 20 1.657E8 16.97 5.49 3 10 1278.33 5.49 3 10 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 5.48 1 0 3 20 1.657E8 16.97 5.48 3 10 1278.33 5.48 3 10 511 55.8 6.89 31559819 keratin 25C [Homo sapiens] 5.45 1 0 3 10 1.691E8 8.22 5.45 3 5 587.47 5.45 3 5 459 49.8 5.14 HVO_C0043 conserved hypothetical protein 5.45 1 3 3 5 8.752E6 2.29 5.45 3 3 124.78 3.33 2 2 661 73.8 4.75 HVO_1052 transcription initiation factor TFB 5.42 1 0 2 6 5.045E7 4.19 5.42 2 3 379.58 5.42 2 3 332 37.3 5.25 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 5.28 1 2 2 8 6.298E7 10.60 5.28 2 4 587.50 5.28 2 4 398 43.4 4.37 HVO_2697 DNA primase small subunit 5.19 1 2 2 7 1.999E7 6.59 5.19 2 4 333.80 5.19 2 3 385 42.6 4.72 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 5.14 1 3 3 8 2.696E7 2.15 5.14 3 4 319.75 5.14 3 4 584 63.3 4.79 HVO_1309 peptidase M24 family protein 5.12 1 2 2 10 3.737E7 11.46 5.12 2 5 738.78 5.12 2 5 391 42.1 4.36 HVO_0148 urease alpha subunit 5.11 1 2 2 5 1.130E7 3.96 5.11 2 3 186.25 5.11 2 2 568 60.3 4.54 HVO_0801 stomatin family protein 4.95 1 2 2 3 2.050E6 1.81 4.95 2 3 424 46.4 4.37 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 4.89 1 3 3 10 1.654E7 9.23 4.89 3 5 396.74 4.89 3 5 573 62.9 4.45 HVO_0568 TrmB family transcription regulator 4.87 1 2 2 5 1.406E7 0.00 4.87 2 2 180.49 4.87 2 3 349 38.3 4.56 HVO_1735 conserved hypothetical protein 4.70 1 3 3 7 8.495E6 0.00 2.73 2 3 235.63 4.70 3 4 660 75.7 4.50 31074631 keratin 1b [Homo sapiens] 4.67 1 0 3 26 4.753E8 22.00 4.67 3 13 1712.45 4.67 3 13 578 61.8 5.97 HVO_2035 TrmB family transcription regulator 4.57 1 2 2 6 4.322E6 1.99 4.57 2 3 192.81 4.57 2 3 372 40.9 5.07 109255249 keratin 4 [Homo sapiens] 4.55 1 0 3 16 2.180E8 17.42 4.55 3 8 998.69 4.55 3 8 594 63.9 8.25 HVO_2846 SpoVR family protein 4.48 1 1 2 2 3.194E7 71.00 4.48 2 2 669 78.0 4.82 HVO_2263 conserved hypothetical protein 4.24 1 3 3 7 1.530E7 6.09 4.24 3 4 305.23 3.25 2 3 801 89.5 5.54 HVO_0811 tyrosine decarboxylase 4.20 1 1 2 2 1.481E7 139.72 4.20 2 2 357 38.5 4.97 HVO_2175 SMC-like protein Sph3 4.13 1 2 2 3 1.126E7 0.00 4.13 2 3 654 74.2 4.54 HVO_A0254 DUF234 domain protein 4.12 1 2 2 2 6.460E6 2.20 4.12 2 2 461 52.7 4.78 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 4.05 1 1 2 4 4.410E7 358.39 4.05 2 4 444 47.1 4.77 31559829 keratin 25A [Homo sapiens] 4.00 1 0 2 8 2.535E8 6.02 4.00 2 4 474.55 4.00 2 4 450 49.3 5.08 HVO_0764 conserved hypothetical protein 3.85 1 1 2 2 1.307E7 0.00 3.85 2 2 260 28.2 4.79 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 3.85 1 3 4 11 1.534E7 3.56 3.26 3 5 439.89 3.85 4 6 858 93.9 4.69 HVO_A0163 proline racemase 3.68 1 2 2 2 2.712E8 0.00 3.68 2 2 353 38.4 4.53 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 3.66 1 2 2 4 1.621E7 1.91 3.66 2 2 186.66 3.66 2 2 437 47.1 4.72 HVO_2071 conserved hypothetical protein 3.64 1 2 2 8 3.154E7 5.88 3.64 2 4 598.58 3.64 2 4 549 58.4 4.72 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 12 1.917E8 10.81 3.63 2 6 761.11 3.63 2 6 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.59 1 0 2 12 1.917E8 10.81 3.59 2 6 761.11 3.59 2 6 529 57.8 7.71 28173564 keratin 6 irs3 [Homo sapiens] 3.52 1 0 2 12 1.917E8 10.81 3.52 2 6 761.11 3.52 2 6 540 58.9 7.23 HVO_1650 polyphosphate kinase 3.49 1 2 2 6 1.197E7 1.77 3.49 2 3 211.86 3.49 2 3 832 93.6 4.65 HVO_0311 A-type ATP synthase subunit I 3.27 1 2 2 8 2.977E7 8.82 3.27 2 4 497.61 3.27 2 4 733 79.5 4.41 66774007 "Keratin, type II cytoskeletal 1b" 2.60 1 0 2 18 2.298E8 11.40 2.60 2 9 956.38 2.60 2 9 576 61.7 5.85 27894337 keratin 20 [Homo sapiens] 2.59 1 0 2 10 1.623E8 14.64 2.59 2 5 798.54 2.59 2 5 424 48.5 5.69 HVO_1940 DNA mismatch repair protein MutS 2.50 1 2 2 4 4.247E6 2.10 2.50 2 2 189.61 2.50 2 2 921 99.4 4.42 HVO_0065 DNA-directed DNA polymerase D large subunit 2.08 1 2 2 5 9.086E6 4.31 2.08 2 3 175.95 2.08 2 2 1202 133.9 4.60 HVO_1400 ABC-type transport system ATP-binding protein (probable substrate sugar) 1.93 1 1 2 2 3.012E6 29.71 1.93 2 2 519 56.8 4.68