Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0356 translation elongation factor aEF-2 86.93 1 57 57 847 9.472E9 780.28 81.43 54 418 50261.32 86.93 56 429 727 80.4 4.73 HVO_0359 translation elongation factor aEF-1 alpha subunit 81.24 1 23 27 928 2.388E10 808.32 76.96 25 432 64819.67 80.05 26 496 421 45.7 4.73 HVO_0880 conserved hypothetical protein 77.52 1 30 30 318 1.882E9 329.14 76.55 29 157 20644.90 77.52 30 161 307 36.3 4.74 HVO_2862 serine hydroxymethyltransferase 77.11 1 19 19 248 3.534E9 217.95 74.94 18 124 14496.17 77.11 19 124 415 44.3 4.53 HVO_0433 F420H2:NADP oxidoreductase 76.13 1 10 10 45 3.710E8 44.66 76.13 10 22 3229.04 76.13 10 23 222 23.3 4.72 HVO_0104 DNA repair and recombination protein RadA 75.80 1 18 18 96 1.114E9 99.50 61.22 16 47 6854.29 75.80 18 49 343 37.3 4.64 HVO_1921 serine--tRNA ligase 74.57 1 30 30 171 1.228E9 176.81 74.57 30 84 11171.63 74.57 30 87 460 52.0 4.46 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 72.29 1 18 18 197 3.890E9 184.51 72.29 18 99 13586.02 72.29 18 98 350 37.6 4.54 HVO_0133 thermosome subunit 1 71.07 1 25 27 236 2.469E9 249.32 71.07 27 120 16220.74 68.04 26 116 560 58.9 4.25 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 69.40 1 16 16 67 5.217E8 63.01 64.77 14 32 3997.80 69.40 16 35 281 30.6 4.59 HVO_1454 aspartate carbamoyltransferase catalytic subunit 69.08 1 12 12 52 2.012E8 51.70 69.08 12 26 3264.91 69.08 12 26 304 33.7 4.92 HVO_1273 inosine-5'-monophosphate dehydrogenase 68.07 1 22 22 228 1.703E9 231.38 57.83 18 110 15189.64 68.07 22 118 498 53.3 4.55 HVO_2900 fumarate hydratase 67.59 1 19 19 146 1.716E9 154.13 65.25 18 74 9326.32 67.59 19 72 469 50.1 4.78 HVO_1637 FKBP-type peptidylprolyl isomerase 66.34 1 12 13 103 4.037E9 97.94 50.98 11 48 7838.22 64.71 12 55 306 33.8 3.76 HVO_0581 "cell division protein FtsZ, type II" 66.25 1 18 18 87 5.662E8 100.76 66.25 18 45 6119.34 66.25 18 42 400 42.5 4.75 HVO_1507 acetolactate synthase small subunit 66.06 1 12 12 56 2.182E8 43.36 66.06 12 28 3505.26 66.06 12 28 218 23.7 4.94 HVO_0055 CBS domain protein 65.14 1 13 13 83 1.274E9 86.53 61.62 12 41 6609.48 65.14 13 42 284 30.8 4.27 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 64.79 1 13 13 54 5.488E8 46.04 64.79 13 27 3199.18 64.79 13 27 355 38.2 4.68 HVO_0348 DNA-directed RNA polymerase subunit B' 64.37 1 33 33 205 1.542E9 215.54 63.38 32 100 13809.46 62.89 32 105 609 67.7 4.92 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 64.16 1 16 16 101 2.151E9 63.55 63.20 15 49 5873.07 64.16 16 52 413 45.8 4.45 HVO_2435 peptidase M24 family protein 63.86 1 13 13 51 1.920E8 53.04 59.51 12 26 3530.54 56.79 12 25 368 40.0 4.53 HVO_0239 glutamine synthetase 62.50 1 22 23 185 4.155E9 193.03 57.02 22 94 12841.95 61.40 22 91 456 50.5 4.56 HVO_0329 branched-chain amino acid aminotransferase 62.50 1 14 14 88 7.987E8 86.66 62.50 14 45 5672.35 62.50 14 43 312 35.0 4.58 HVO_0677 aspartate--tRNA ligase 62.44 1 21 21 310 5.044E9 344.77 62.44 21 161 21250.36 62.44 21 149 434 48.7 4.50 HVO_1133 conserved hypothetical protein 62.38 1 5 5 17 2.010E8 15.73 62.38 5 9 1253.98 55.45 4 8 101 11.7 4.58 HVO_1550 acyl-CoA thioester hydrolase 61.88 1 5 5 15 1.219E8 11.54 30.63 3 6 938.73 61.88 5 9 160 17.6 4.55 HVO_2588 isocitrate dehydrogenase (NADP) 61.34 1 22 22 178 4.175E9 170.57 58.23 21 89 11920.55 53.94 21 89 419 45.8 4.59 HVO_0778 thermosome subunit 3 61.26 1 23 25 150 1.191E9 136.65 58.02 24 77 9973.64 61.07 24 73 524 55.2 4.59 HVO_0167 adenosylhomocysteinase 60.28 1 18 18 138 6.866E8 100.41 56.07 17 71 7268.56 58.64 16 67 428 46.6 4.39 HVO_0347 DNA-directed RNA polymerase subunit B'' 60.27 1 30 30 188 1.149E9 130.53 60.27 30 94 11228.94 60.08 29 94 521 58.9 5.00 HVO_0161 ATP phosphoribosyltransferase 60.14 1 13 13 54 3.381E8 50.27 60.14 13 27 3479.02 60.14 13 27 281 30.4 4.60 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 59.79 1 11 11 53 3.172E8 60.11 59.79 11 27 3365.02 59.79 11 26 286 31.2 4.54 HVO_0829 peptidase S9 family protein 59.70 1 22 22 84 3.538E8 70.47 59.70 22 42 4236.78 59.70 22 42 608 67.4 4.54 HVO_1332 conserved hypothetical protein 59.69 1 7 7 19 1.448E8 15.28 34.88 5 8 1233.76 59.69 7 11 129 14.9 4.16 HVO_2413 translation elongation factor aEF-1 alpha subunit 59.52 1 14 18 168 4.103E9 115.49 55.24 17 83 8775.63 59.52 18 85 420 45.6 4.75 HVO_2969 threonine synthase 59.43 1 18 18 105 1.631E9 91.97 59.43 18 52 7223.71 59.43 18 53 419 44.4 4.49 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 59.11 1 17 17 144 2.231E9 191.02 59.11 17 73 12714.80 59.11 17 71 384 41.4 4.41 HVO_1684 threonine--tRNA ligase 59.10 1 33 33 171 1.264E9 152.38 59.10 33 86 11146.84 55.21 32 85 643 73.4 4.45 HVO_2724 beta-lactamase domain protein 58.89 1 19 19 203 1.758E9 200.33 58.89 19 101 11879.00 58.89 19 102 450 50.1 5.40 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 58.79 1 15 15 133 4.241E9 107.13 58.79 15 66 7856.72 58.79 15 67 381 41.0 4.23 HVO_2968 phosphoglycerate dehydrogenase 58.67 1 22 22 200 3.106E9 253.66 58.67 22 101 16027.63 57.52 21 99 525 55.3 4.36 HVO_0850 proteasome-activating nucleotidase 58.52 1 17 18 118 4.859E8 128.41 53.33 17 59 8781.51 58.52 18 59 405 45.6 4.60 HVO_0025 thiosulfate sulfurtransferase 58.04 1 10 10 115 3.996E9 99.11 58.04 10 54 7471.99 58.04 10 61 286 32.1 4.28 HVO_1541 glycerol kinase 58.04 1 23 23 120 2.035E9 104.38 54.71 22 59 7731.61 58.04 23 61 510 56.7 4.50 HVO_2191 formyltetrahydrofolate deformylase 57.19 1 15 15 48 4.480E8 43.25 54.13 14 23 2774.75 57.19 15 25 327 36.2 4.63 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 57.14 1 14 14 79 3.479E8 85.39 57.14 14 39 5929.65 53.35 13 40 343 38.4 4.94 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 56.90 1 13 13 69 7.575E8 52.69 52.19 12 34 3383.06 56.57 12 35 297 31.3 4.36 HVO_0008 aspartate kinase 56.89 1 12 12 68 1.708E9 56.93 56.89 12 35 3626.89 55.36 11 33 392 41.7 4.46 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 56.73 1 25 25 160 1.101E9 148.54 54.17 24 82 10210.86 56.73 25 78 624 67.6 4.27 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 56.59 1 25 25 175 1.832E9 150.08 53.89 23 88 10956.57 56.59 25 87 592 66.6 4.61 HVO_0400 conserved hypothetical protein 56.35 1 4 4 12 8.726E7 10.42 56.35 4 6 810.98 56.35 4 6 126 13.9 4.68 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 55.80 1 15 15 75 5.024E8 84.45 55.80 15 38 5150.65 55.80 15 37 457 48.4 4.35 HVO_2624 CTP synthase 55.74 1 24 24 150 9.363E8 115.94 52.28 21 72 8832.95 55.74 24 78 549 60.8 4.70 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 55.45 1 11 11 139 2.620E9 134.38 55.45 11 72 8646.07 52.88 10 67 312 34.5 4.98 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 55.45 1 14 14 57 2.103E8 47.49 55.45 14 28 3172.43 55.45 14 29 422 43.6 4.72 HVO_0861 SufB domain protein 54.98 1 16 16 111 1.658E9 130.11 51.49 15 53 9031.85 54.98 16 58 402 44.7 4.23 HVO_B0118 SMC-like protein Sph2 54.66 1 30 30 141 1.089E9 140.79 54.66 30 72 8408.33 52.48 29 69 644 73.8 4.41 HVO_0046 putative glutamate--argW ligase 54.64 1 12 12 62 7.276E8 56.92 54.64 12 30 4598.02 54.64 12 32 291 31.9 4.87 HVO_0859 FeS assembly ATPase SufC 54.49 1 15 15 132 2.044E9 123.83 50.83 13 65 9242.79 52.16 14 67 301 33.4 4.35 HVO_0602 3-dehydroquinate dehydratase 54.25 1 10 10 42 1.276E8 26.07 54.25 10 22 1937.89 47.37 9 20 247 27.3 4.51 HVO_0869 glutamate synthase large subunit 53.87 1 66 67 418 1.679E9 397.44 53.47 66 212 27329.80 53.87 67 206 1511 163.8 4.70 HVO_2621 phosphoenolpyruvate carboxylase 53.62 1 39 39 289 1.500E9 278.86 53.51 38 144 18247.56 52.73 38 145 897 102.3 4.64 HVO_2059 NAD-dependent epimerase/dehydratase 53.55 1 12 12 55 4.612E8 45.94 53.55 12 27 3406.65 53.55 12 28 310 34.1 4.40 HVO_2013 "FtsZ family protein, type III" 53.30 1 11 11 52 4.100E8 65.31 53.30 11 26 4006.39 53.30 11 26 394 41.5 4.61 HVO_0870 proline--tRNA ligase 53.28 1 17 17 103 9.186E8 88.19 50.41 15 49 6267.59 53.28 17 54 488 54.9 4.44 HVO_1649 methionine adenosyltransferase 53.23 1 15 15 74 4.828E8 69.75 53.23 15 38 4774.97 53.23 15 36 402 43.5 4.45 HVO_1189 aldehyde dehydrogenase 53.15 1 21 21 84 1.116E9 79.37 45.67 19 40 5417.86 51.77 20 44 508 56.1 4.59 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 53.11 1 16 16 87 1.183E9 59.70 48.20 15 40 5411.03 53.11 16 47 305 33.8 4.74 HVO_0788 tryptophan synthase beta subunit 52.84 1 15 15 61 3.431E8 58.10 52.84 15 32 3720.90 52.84 15 29 422 45.7 4.65 HVO_0317 A-type ATP synthase subunit B 52.78 1 17 18 134 2.903E9 159.57 52.78 18 68 10222.37 52.78 16 66 468 51.9 4.25 HVO_0651 prefoldin beta subunit 52.76 1 3 3 5 5.911E7 2.64 30.71 2 2 187.39 52.76 3 3 127 14.0 4.07 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 52.59 1 21 21 75 4.200E8 93.18 52.59 21 38 5977.74 50.08 20 37 599 65.3 4.51 HVO_0792 3-dehydroquinate synthase type II 52.04 1 15 15 83 6.282E8 93.99 50.77 14 41 6205.48 44.90 14 42 392 43.1 4.44 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 51.90 1 17 17 90 4.053E8 97.31 51.90 17 46 6031.20 51.90 16 44 474 53.4 4.59 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 51.90 1 9 9 97 1.854E9 116.35 48.79 8 49 7679.72 51.90 9 48 289 29.8 4.27 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 51.76 1 24 24 116 5.904E8 102.36 49.68 23 59 7429.44 51.76 24 57 626 67.6 4.65 HVO_2774 enolase 51.63 1 13 13 72 1.208E9 68.94 51.63 13 37 5062.75 46.12 12 35 399 42.0 4.37 HVO_0455 thermosome subunit 2 51.53 1 27 28 189 1.688E9 181.52 51.53 28 94 12482.82 51.53 28 95 557 59.3 4.37 HVO_2552 30S ribosomal protein S4e 51.42 1 9 9 91 3.751E9 84.96 51.42 9 47 4932.83 48.99 8 44 247 26.6 4.58 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 51.39 1 11 11 60 3.379E8 47.06 51.39 11 31 3673.73 43.61 10 29 360 39.6 4.39 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 51.38 1 19 19 89 7.468E8 89.74 46.92 17 43 5683.84 51.38 19 46 471 51.0 4.48 HVO_2889 RecJ domain protein 51.17 1 32 32 180 2.050E9 165.61 51.17 32 89 12437.26 50.34 31 91 729 79.1 4.37 HVO_0203 replication factor C small subunit 51.07 1 14 14 57 2.257E8 51.12 51.07 14 28 3860.24 51.07 14 29 327 36.2 4.51 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 51.03 1 23 23 315 5.435E9 307.37 49.76 22 155 22086.93 51.03 23 160 631 68.4 4.49 HVO_1957 proteasome-activating nucleotidase 50.49 1 12 13 49 1.865E8 37.12 50.49 13 25 2482.59 50.49 13 24 412 45.6 4.48 HVO_0874 beta-lactamase domain protein 50.47 1 26 26 117 8.956E8 114.74 49.53 25 57 8075.78 50.47 26 60 640 71.9 5.14 HVO_2544 30S ribosomal protein S5 50.47 1 10 10 49 1.449E9 35.72 50.47 10 25 2413.83 47.66 9 24 214 23.3 9.29 HVO_2336 pyridoxal biosynthesis lyase PdxS 50.33 1 14 14 73 4.087E8 69.58 39.74 11 33 4497.18 50.33 14 40 302 32.5 4.81 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 50.30 1 14 14 49 2.305E8 33.92 41.96 12 23 2780.21 50.30 14 26 336 38.0 4.61 HVO_2015 conserved hypothetical protein 50.14 1 12 12 166 6.529E9 171.73 48.12 11 83 12018.65 50.14 12 83 345 37.7 4.25 HVO_0212 homolog to lactoylglutathione lyase 50.00 1 4 4 16 3.031E8 21.93 50.00 4 8 1366.97 50.00 4 8 124 13.5 4.13 HVO_2646 dihydroxy-acid dehydratase 50.00 1 21 21 152 1.492E9 162.67 50.00 21 77 10818.25 50.00 21 75 584 61.8 4.42 HVO_2348 GTP cyclohydrolase MptA 49.68 1 9 9 45 2.309E8 11.34 40.58 8 23 1760.58 49.68 9 22 308 33.5 4.68 HVO_0206 alanine--tRNA ligase 49.57 1 32 32 193 4.438E8 188.73 48.70 31 95 12395.27 49.57 32 98 922 102.4 4.54 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 49.44 1 14 14 83 4.299E8 93.70 49.44 14 40 5570.83 49.44 14 43 445 47.8 4.86 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 49.41 1 15 15 70 3.188E8 61.49 49.41 15 35 3996.85 49.41 15 35 340 38.8 4.58 HVO_2384 CBS domain protein 49.21 1 16 16 100 7.768E8 70.06 46.84 15 50 5468.01 49.21 16 50 380 42.5 5.01 HVO_1145 30S ribosomal protein S1e 49.09 1 10 10 44 4.547E8 41.40 49.09 10 22 2851.39 49.09 10 22 220 24.8 4.86 HVO_0980 NADH dehydrogenase-like complex subunit CD 49.01 1 15 19 84 3.786E8 64.52 41.11 17 42 4716.42 44.52 18 42 557 63.4 4.53 HVO_0999 DRTGG domain protein 48.94 1 13 13 71 4.121E8 88.53 48.94 13 35 5723.77 48.94 13 36 378 39.8 4.44 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 48.81 1 24 24 237 2.941E9 201.43 46.76 22 121 15493.92 48.81 24 116 586 64.0 4.49 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 48.79 1 11 11 52 2.475E8 48.59 46.36 9 25 3300.06 48.79 11 27 330 36.3 4.35 HVO_1132 adenylosuccinate synthase 48.76 1 24 24 168 2.042E9 128.57 45.60 23 83 9754.23 47.18 23 85 443 48.2 4.56 HVO_0789 tryptophan synthase alpha subunit 48.74 1 8 8 42 3.388E8 35.77 48.74 8 22 2274.49 48.74 8 20 277 29.6 4.21 HVO_2519 conserved hypothetical protein 48.69 1 13 13 70 7.552E8 77.86 43.98 12 34 5802.59 48.69 13 36 382 40.7 4.35 HVO_0860 SufB domain protein 48.11 1 17 17 154 1.488E9 156.55 39.71 15 73 10663.17 48.11 17 81 476 53.2 4.69 HVO_2726 glutamate--tRNA ligase 48.03 1 22 22 94 3.473E8 69.94 42.22 20 46 5251.07 48.03 22 48 585 65.2 4.58 HVO_0393 UvrABC system protein A 48.02 1 35 36 133 2.062E8 115.49 47.20 35 67 8259.34 47.51 35 66 983 108.6 4.82 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 47.98 1 22 22 127 8.651E8 97.94 46.37 21 62 7861.82 47.98 22 65 496 55.0 4.53 HVO_0480 phosphoglycerate kinase 47.88 1 18 18 88 8.663E8 103.16 46.13 16 43 7242.49 47.88 18 45 401 43.6 4.37 HVO_0388 homolog to ribonuclease R 47.84 1 17 17 99 4.172E8 104.56 42.14 16 48 7157.69 47.84 17 51 439 50.3 4.73 HVO_1172 NAD-dependent epimerase/dehydratase 47.62 1 10 10 38 9.281E8 31.67 38.10 8 18 2876.40 37.46 9 20 315 34.9 4.34 HVO_1504 3-isopropylmalate dehydratase large subunit 47.36 1 18 19 139 2.587E9 134.80 47.36 19 68 10680.42 47.36 19 71 473 51.6 4.55 HVO_A0207 CRISPR-associated protein Cas7 47.35 1 10 10 42 6.225E8 51.99 44.41 9 20 3122.87 47.35 10 22 340 38.2 4.54 HVO_2558 30S ribosomal protein S3 47.04 1 12 12 136 3.031E9 130.87 42.76 11 67 10555.53 47.04 12 69 304 33.4 4.06 HVO_1506 ketol-acid reductoisomerase 46.84 1 9 9 81 1.094E9 87.58 40.80 8 37 5325.31 46.84 9 44 348 37.9 4.34 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 46.80 1 14 14 60 3.673E8 52.80 46.80 14 30 3468.70 44.81 13 30 453 47.5 4.63 HVO_2487 aspartate-semialdehyde dehydrogenase 46.80 1 10 10 75 1.390E9 74.36 46.80 10 37 4696.35 46.80 10 38 344 36.6 4.41 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 46.79 1 10 10 50 9.404E8 59.37 46.79 10 24 3984.18 46.79 10 26 280 30.1 4.44 HVO_2961 dihydrolipoyl dehydrogenase 46.74 1 15 15 70 2.534E8 75.03 41.26 14 35 4629.84 46.74 14 35 475 49.9 4.41 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 46.73 1 10 10 55 5.373E8 70.41 41.37 9 27 4956.09 45.54 9 28 336 36.8 4.12 HVO_0240 Lrp/AsnC family transcription regulator 46.71 1 6 7 24 4.397E8 10.00 41.45 6 12 1487.56 46.71 7 12 152 16.9 4.39 HVO_1973 conserved hypothetical protein 46.71 1 4 4 23 9.317E7 25.65 37.72 3 11 1603.81 46.71 4 12 167 18.1 4.36 HVO_0809 methionine--tRNA ligase 46.62 1 24 24 123 7.255E8 126.33 46.62 24 62 8610.24 46.62 24 61 740 81.9 4.37 HVO_1134 conserved hypothetical protein 46.50 1 26 26 115 3.952E8 110.83 46.50 26 58 7130.54 46.50 24 57 757 80.6 4.35 HVO_0717 "cell division protein FtsZ, type I" 46.44 1 16 16 94 1.486E9 93.02 46.44 16 47 6789.37 46.44 16 47 379 39.8 4.40 HVO_2700 AAA-type ATPase (CDC48 subfamily) 46.42 1 35 36 136 3.827E8 107.87 46.42 36 68 7653.75 42.57 34 68 754 82.8 4.75 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 46.34 1 10 10 109 1.657E9 110.32 46.34 10 57 7336.30 43.55 9 52 287 31.0 4.73 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 46.24 1 10 10 72 6.116E8 74.00 46.24 10 36 5382.45 46.24 10 36 266 27.8 4.84 HVO_2204 "FtsZ family protein, type III" 46.08 1 14 16 91 1.356E9 100.05 44.56 15 44 7157.66 44.30 15 47 395 42.0 4.68 HVO_1590 DnaK-type molecular chaperone Hsp70 45.92 1 25 25 188 2.512E9 171.04 45.92 25 94 12242.12 45.92 25 94 625 67.2 4.18 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 45.65 1 6 6 26 3.405E8 37.85 40.22 5 12 2516.32 45.65 6 14 184 19.8 5.30 HVO_0661 dCTP deaminase (dUMP-forming) 45.64 1 6 6 29 9.150E7 22.23 45.64 6 15 1262.91 45.64 6 14 195 21.2 4.59 HVO_1084 adenylosuccinate lyase 45.36 1 16 16 69 3.532E8 54.04 37.80 14 34 4521.15 40.82 15 35 463 50.8 4.70 HVO_1577 conserved hypothetical protein 45.20 1 8 8 30 2.786E8 34.22 34.46 6 14 2473.32 45.20 8 16 177 19.4 4.74 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 44.63 1 11 11 58 2.183E8 49.94 44.63 11 29 3358.97 44.63 11 29 363 39.3 4.97 HVO_0806 pyruvate kinase 44.62 1 19 19 144 1.458E9 149.04 44.62 19 71 10138.64 44.62 19 73 585 62.0 4.54 HVO_1572 DNA gyrase subunit B 44.44 1 26 26 110 3.525E8 92.70 44.44 26 56 6272.97 44.44 26 54 639 71.2 4.83 HVO_0519 replication protein A 44.31 1 18 18 96 4.773E8 74.89 44.31 18 48 6086.15 44.31 18 48 483 51.0 4.13 HVO_A0636 YbaK domain protein 44.30 1 4 4 20 1.072E8 29.89 44.30 4 10 1834.69 44.30 4 10 158 16.7 4.54 HVO_1082 homolog to orotate phosphoribosyltransferase 44.29 1 9 9 29 2.217E8 20.34 44.29 9 14 1630.44 44.29 9 15 210 22.3 4.42 HVO_2981 uracil phosphoribosyltransferase 44.25 1 8 8 36 6.622E8 40.95 36.73 7 16 3046.80 44.25 8 20 226 24.5 4.49 HVO_B0059 cobalt-precorrin 5A hydrolase 44.17 1 12 12 58 3.165E8 55.78 44.17 12 29 4087.52 44.17 12 29 326 34.5 4.51 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 44.06 1 7 7 29 6.571E7 22.29 44.06 7 15 1850.92 38.61 6 14 202 22.2 5.11 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 44.00 1 17 17 102 9.412E8 101.61 42.10 15 49 7097.84 44.00 17 53 525 56.4 4.40 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 44.00 1 22 22 103 3.628E8 93.14 41.67 19 50 6861.29 44.00 22 53 600 65.3 4.68 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 43.95 1 41 41 259 1.163E9 219.58 42.50 39 126 16840.70 43.95 41 133 1033 114.3 4.45 HVO_2454 anthranilate synthase component I 43.89 1 19 19 70 2.818E8 70.37 43.89 19 35 5091.75 43.89 19 35 524 55.9 4.56 HVO_0243 threonine aldolase 43.70 1 10 10 40 1.139E8 44.95 43.70 10 20 2926.56 43.70 10 20 341 35.6 4.55 HVO_0353 30S ribosomal protein S12 43.66 1 9 9 43 3.467E8 44.09 43.66 9 21 2506.29 43.66 9 22 142 15.5 9.91 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 43.63 1 9 9 49 6.172E8 52.71 43.63 9 25 3900.82 43.63 9 24 259 28.0 4.50 HVO_1338 replication protein A 43.56 1 13 13 50 2.061E8 46.46 41.92 12 26 3225.38 43.56 13 24 427 46.0 4.36 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 43.55 1 16 16 73 6.112E8 65.28 43.55 16 37 5483.36 40.63 15 36 512 53.8 4.78 HVO_0415 repair helicase 43.51 1 20 20 101 4.844E8 99.47 43.51 20 49 7262.50 43.51 20 52 616 69.6 4.70 HVO_1690 DHH family phosphoesterase 43.51 1 12 12 51 1.510E8 55.57 43.51 12 26 3248.49 38.56 11 25 485 52.1 4.48 HVO_2419 hydroxymethylglutaryl-CoA synthase 43.15 1 14 14 79 5.474E8 55.75 43.15 14 38 4208.50 43.15 14 41 445 50.1 4.64 HVO_0118 50S ribosomal protein L20e 43.10 1 2 2 6 1.526E7 7.25 43.10 2 3 466.61 43.10 2 3 58 6.4 6.52 HVO_1545 dihydroxyacetone kinase subunit DhaL 43.10 1 8 8 38 4.602E8 31.31 43.10 8 19 2249.56 43.10 8 19 232 24.8 4.48 HVO_1123 thioredoxin-disulfide reductase 42.98 1 10 10 47 7.217E8 37.43 39.83 9 23 2622.51 32.09 9 24 349 37.3 4.32 HVO_2783 30S ribosomal protein S4 42.86 1 9 9 48 5.880E8 42.92 42.86 9 24 3147.32 42.86 9 24 175 20.1 5.24 HVO_2188 phosphoribosylformylglycinamidine synthase 1 42.41 1 7 7 30 3.754E8 29.06 42.41 7 15 2355.22 42.41 7 15 224 23.9 4.36 HVO_1571 DNA topoisomerase VI subunit B 42.23 1 23 23 95 4.704E8 88.77 39.85 22 46 6188.45 42.23 23 49 798 87.4 4.73 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 42.21 1 21 21 82 4.742E8 78.74 39.66 19 40 6118.88 41.36 20 42 706 73.3 4.39 HVO_0087 porphobilinogen synthase 42.20 1 9 9 30 1.252E8 18.47 42.20 9 15 1454.51 42.20 9 15 327 35.3 4.72 HVO_1370 gamma-glutamyl phosphate reductase 42.12 1 15 15 78 5.383E8 73.86 42.12 15 38 4848.12 42.12 15 40 444 48.1 4.34 HVO_1031 thioredoxin-disulfide reductase 42.11 1 9 9 45 3.222E8 42.25 37.43 8 22 3010.88 42.11 9 23 342 37.4 4.46 HVO_2057 sugar nucleotidyltransferase 42.02 1 13 13 75 7.834E8 71.08 42.02 13 37 5341.98 42.02 13 38 357 37.8 4.44 HVO_1295 histidinol-phosphate aminotransferase 41.83 1 13 13 38 1.081E8 24.51 41.83 12 18 2024.92 40.17 12 20 361 39.4 4.51 HVO_1824 conserved hypothetical protein 41.72 1 13 13 56 3.140E8 56.50 41.72 13 28 4095.45 41.72 13 28 429 47.4 4.20 HVO_2756 50S ribosomal protein L10 41.67 1 10 10 50 5.320E8 33.35 41.67 10 25 3222.54 41.67 10 25 348 36.9 3.99 HVO_0109 cysteine desulfurase 41.55 1 14 14 71 3.315E8 54.36 41.55 14 36 4095.24 41.55 14 35 426 46.8 4.56 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 41.38 1 11 11 50 1.061E9 50.53 37.01 10 26 3255.51 41.38 11 24 435 46.9 4.63 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 41.31 1 12 12 88 9.086E8 54.08 37.45 11 42 4968.93 41.31 12 46 259 29.9 4.36 HVO_0316 A-type ATP synthase subunit A 41.30 1 20 20 139 1.817E9 170.95 41.30 20 70 10978.36 41.30 19 69 586 64.5 4.25 HVO_2813 RimK family protein 41.28 1 14 14 79 6.217E8 82.97 39.96 13 40 5864.64 41.28 14 39 453 49.0 4.73 HVO_1967 glucose-6-phosphate isomerase 41.16 1 11 11 47 2.489E8 47.83 41.16 11 23 3141.94 41.16 11 24 430 45.6 4.40 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 41.13 1 7 7 30 1.843E8 21.67 41.13 7 15 1674.76 41.13 7 15 231 25.0 4.25 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 41.13 1 9 9 31 7.868E7 34.56 41.13 9 15 2218.70 41.13 9 16 265 28.7 4.87 HVO_0449 prephenate dehydratase 41.04 1 8 8 34 3.828E8 32.88 41.04 8 17 2258.32 41.04 8 17 268 28.7 4.64 HVO_2759 peptidase M42 family protein 40.96 1 10 10 43 1.225E8 37.11 40.96 10 22 2417.10 32.77 9 21 354 37.0 4.40 HVO_0024 thiosulfate sulfurtransferase 40.70 1 8 8 32 3.421E8 27.37 36.05 7 16 2145.11 40.70 8 16 258 28.4 4.30 HVO_2948 phenylalanine--tRNA ligase alpha subunit 40.68 1 11 11 53 4.955E8 41.40 40.68 11 27 2340.56 37.27 10 26 499 55.1 4.41 HVO_1778 catalase-peroxidase 40.67 1 17 17 75 9.401E8 80.84 40.67 17 38 5519.85 32.87 15 37 718 80.0 4.31 HVO_1300 triosephosphate isomerase 40.65 1 5 5 31 7.397E8 25.93 40.65 5 16 1965.22 40.65 5 15 214 21.3 4.26 HVO_0349 DNA-directed RNA polymerase subunit A' 40.57 1 31 31 168 6.891E8 170.81 40.16 30 84 12392.62 39.86 30 84 976 108.8 4.81 HVO_2779 50S ribosomal protein L18e 40.52 1 4 4 10 1.228E7 7.89 40.52 4 5 519.82 40.52 4 5 116 12.7 8.50 HVO_1080 conserved hypothetical protein 40.43 1 5 5 18 9.978E7 17.11 40.43 5 9 1006.70 40.43 5 9 188 21.1 4.31 HVO_1502 3-isopropylmalate dehydrogenase 40.43 1 11 11 85 1.373E9 74.10 40.43 11 44 5791.70 40.43 11 41 324 33.7 4.23 HVO_0551 DNA mismatch repair protein MutL 40.41 1 18 18 48 1.178E8 50.19 39.18 17 25 3392.50 33.06 16 23 735 78.7 4.50 HVO_1955 aconitate hydratase 40.37 1 24 24 199 3.933E9 197.15 39.45 23 99 14508.21 40.37 24 100 654 70.4 4.45 HVO_1327 AAA-type ATPase (CDC48 subfamily) 40.35 1 19 20 72 2.257E8 42.29 40.35 20 36 3107.23 40.35 20 36 736 78.1 4.88 HVO_A0206 CRISPR-associated protein Cas8b 40.31 1 21 22 94 3.493E8 72.50 39.61 21 47 5442.23 40.31 22 47 717 79.3 4.60 HVO_0100 NMD3 family protein 40.27 1 9 9 38 9.128E7 42.58 40.27 9 19 2636.81 40.27 9 19 375 41.6 4.46 HVO_1306 chorismate synthase 40.26 1 13 13 73 3.021E8 87.75 40.26 13 36 5014.86 40.26 13 37 385 41.9 4.83 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 37 1.536E8 38.37 40.26 5 19 2687.19 40.26 5 18 154 17.5 4.50 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 16 2.983E8 16.60 40.00 4 8 1074.02 40.00 4 8 130 14.1 4.79 HVO_1854 histidine--tRNA ligase 39.91 1 15 15 75 5.117E8 90.86 39.91 15 38 5383.09 39.91 15 37 431 47.1 4.37 HVO_2225 AstE family protein 39.88 1 7 7 31 3.474E8 35.52 31.96 6 15 2302.51 39.88 7 16 341 36.9 4.53 HVO_1212 KaiC-type circadian regulator CirA 39.84 1 9 9 44 7.664E8 50.17 39.84 9 22 3711.95 39.84 9 22 246 27.5 4.45 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 39.76 1 7 7 30 2.180E8 27.94 39.76 7 15 1967.75 39.76 7 15 254 26.9 4.42 HVO_0324 arginine--tRNA ligase 39.69 1 19 19 108 9.862E8 110.43 39.69 19 54 7688.07 39.69 19 54 587 65.0 4.35 HVO_1901 translation initiation factor aIF-2 gamma subunit 39.66 1 13 13 64 1.130E9 43.29 37.96 12 32 3449.33 39.17 12 32 411 43.9 4.36 HVO_1546 dihydroxyacetone kinase subunit DhaK 39.46 1 11 11 76 7.318E8 38.02 39.46 11 38 3451.77 39.46 11 38 332 34.8 4.22 HVO_2883 conserved hypothetical protein 39.46 1 20 20 63 1.140E8 61.42 37.32 19 32 4289.75 35.61 18 31 702 78.9 4.48 HVO_0424 ABC-type transport system ATP-binding protein 39.40 1 18 18 103 3.970E8 94.33 37.42 17 52 5888.61 39.40 18 51 604 67.2 4.49 HVO_2861 conserved hypothetical protein 39.27 1 9 9 37 3.641E8 34.07 28.36 8 18 2284.88 39.27 9 19 275 29.1 4.27 HVO_2690 GFO family oxidoreductase 39.07 1 11 11 55 6.839E8 46.87 39.07 11 27 3541.74 39.07 11 28 366 40.0 4.60 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 39.05 1 16 16 66 2.758E8 35.34 39.05 16 34 3048.12 37.09 15 32 461 50.7 4.73 HVO_1623 conserved hypothetical protein 38.93 1 7 7 31 1.674E8 21.80 38.93 7 15 1760.10 35.91 6 16 298 32.8 4.56 HVO_A0458 ParA domain protein 38.83 1 7 7 19 7.099E7 17.43 38.83 7 10 967.85 33.68 6 9 291 32.2 4.79 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 38.79 1 14 14 76 4.311E8 75.80 38.79 14 38 4573.96 38.79 14 38 348 38.2 4.32 HVO_0313 A-type ATP synthase subunit E 38.66 1 5 5 23 1.451E8 24.39 31.44 4 10 1787.50 38.66 5 13 194 22.0 4.31 HVO_0321 peptide chain release factor aRF-1 38.65 1 12 13 46 2.076E8 32.60 37.20 12 23 2359.65 36.71 12 23 414 46.6 4.83 HVO_0467 PhoU/TrkA-C domain protein 38.56 1 12 12 39 8.230E7 26.00 38.56 12 20 2413.07 38.56 12 19 402 43.3 4.49 HVO_A0432 conserved hypothetical protein 38.52 1 1 10 36 1.828E8 27.77 38.52 10 18 2144.36 38.52 10 18 405 44.5 5.24 HVO_A0406 conserved hypothetical protein 38.52 1 1 10 39 2.553E8 27.77 38.52 10 20 2195.37 38.52 10 19 405 44.4 5.30 HVO_0812 phosphoenolpyruvate synthase 38.37 1 22 22 76 2.075E8 59.44 36.40 21 38 4811.81 34.69 21 38 761 83.1 4.63 HVO_1531 UDP-glucose 6-dehydrogenase 38.37 1 13 13 49 1.163E8 35.45 38.37 13 25 2835.00 38.37 12 24 430 45.9 4.50 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 38.21 1 13 13 58 5.935E8 51.07 38.21 13 29 3738.80 32.51 12 29 526 57.2 4.31 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 38.14 1 4 4 19 1.361E8 10.74 38.14 4 9 1121.80 38.14 4 10 97 10.8 4.53 HVO_2436 malic enzyme (NADP) 38.08 1 19 23 121 3.485E8 115.04 38.08 23 60 7448.25 38.08 23 61 751 81.4 4.55 HVO_2773 30S ribosomal protein S2 38.08 1 7 7 45 2.079E9 54.49 38.08 7 22 4013.98 38.08 7 23 260 28.3 4.16 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 87 8.801E8 110.56 35.50 8 43 6514.79 38.05 9 44 431 46.1 4.48 HVO_2717 alanine--tRNA ligase 37.94 1 11 11 40 1.725E8 41.52 33.42 9 19 2866.63 37.94 11 21 398 41.6 4.39 HVO_2029 Lrp/AsnC family transcription regulator 37.91 1 3 4 15 2.192E8 4.68 32.03 3 7 596.67 37.91 4 8 153 16.9 4.21 17318569 keratin 1 [Homo sapiens] 37.89 1 1 24 161 8.680E8 166.00 37.89 24 80 11069.17 37.89 24 81 644 66.0 8.12 HVO_A0205 CRISPR-associated endoribonuclease Cas6 37.87 1 8 8 38 2.387E8 44.24 37.87 8 19 2846.55 37.87 8 19 272 31.0 5.44 HVO_0049 argininosuccinate synthase 37.78 1 15 15 72 1.310E9 55.49 37.78 15 36 3924.39 37.78 15 36 405 44.5 4.34 HVO_0417 metal-dependent carboxypeptidase 37.65 1 14 14 59 2.596E8 52.33 34.26 13 29 3893.72 37.65 14 30 502 57.3 4.42 HVO_2189 phosphoribosylformylglycinamidine synthase component PurS 37.35 1 2 3 7 3.885E7 3.94 37.35 3 4 248.18 31.33 2 3 83 9.3 4.50 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 37.31 1 3 3 5 1.688E7 2.52 30.60 2 2 313.94 37.31 3 3 134 13.9 4.55 HVO_0743 probable phosphodiesterase 37.19 1 20 20 118 9.313E8 97.75 36.75 19 58 7218.41 37.19 20 60 449 50.5 4.56 HVO_0406 RNA-binding protein AU-1 36.97 1 13 13 42 1.532E8 26.38 36.97 13 21 1964.69 36.97 13 21 468 49.9 4.53 HVO_1076 sugar nucleotidyltransferase 36.96 1 8 8 43 6.740E8 41.43 36.96 8 23 2933.72 36.96 8 20 322 35.8 4.20 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 36.84 1 5 5 28 4.716E8 19.18 36.84 5 14 1818.17 36.84 5 14 190 20.6 4.30 HVO_0314 A-type ATP synthase subunit C 36.78 1 12 12 32 2.464E8 18.66 32.76 11 15 2140.47 36.78 12 17 348 38.7 4.50 HVO_B0061 precorrin-2 C20-methyltransferase 36.60 1 7 7 28 1.737E8 15.11 36.60 7 14 1712.20 36.60 7 14 235 25.3 4.63 HVO_3007 malate dehydrogenase 36.51 1 12 12 166 2.748E9 141.61 36.51 12 82 9116.75 36.51 12 84 304 32.6 4.40 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 36.49 1 0 23 157 8.680E8 161.13 36.49 23 78 10792.83 36.49 23 79 644 66.0 8.12 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 36.47 1 13 13 78 5.083E8 72.44 35.12 12 38 4645.56 36.47 13 40 447 48.5 4.56 HVO_0041 ornithine carbamoyltransferase 36.45 1 7 7 48 2.893E8 52.73 36.45 7 24 3059.82 36.45 7 24 299 32.7 4.37 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 36.28 1 15 16 76 3.881E8 89.07 36.28 16 37 5323.08 36.28 16 39 623 62.1 5.30 HVO_1371 glutamate 5-kinase 36.21 1 8 8 35 4.500E8 29.17 36.21 8 18 2551.26 36.21 8 17 301 32.0 4.25 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 36.19 1 9 9 29 2.374E8 27.60 33.15 8 14 1785.88 36.19 9 15 362 39.6 4.82 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 36.15 1 13 13 55 2.265E8 39.31 36.15 13 27 2592.39 36.15 13 28 473 50.8 4.58 HVO_1091 proteasome alpha subunit 36.11 1 8 9 44 5.366E8 50.91 33.33 8 22 3182.94 36.11 9 22 252 27.6 4.56 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 36.08 1 4 4 33 9.712E8 27.65 25.26 3 13 3073.48 36.08 4 20 194 20.7 4.12 HVO_2675 histidinol dehydrogenase 35.98 1 11 11 51 4.267E8 48.36 35.98 11 25 3614.37 35.98 11 26 428 45.4 4.50 HVO_2947 phenylalanine--tRNA ligase beta subunit 35.96 1 15 15 60 4.305E8 49.73 32.28 12 29 4155.66 35.96 15 31 570 63.3 4.46 47132620 keratin 2a [Homo sapiens] 35.84 1 12 19 72 5.859E8 63.91 35.84 19 36 4978.69 35.84 19 36 639 65.4 8.00 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 35.84 1 7 7 52 5.431E8 47.08 35.84 7 26 3407.31 35.84 7 26 226 25.5 4.25 HVO_0122 phosphoglycerate dehydrogenase 35.80 1 7 7 17 4.302E7 12.22 28.70 5 8 859.55 23.46 6 9 324 35.3 5.35 HVO_2380 AAA-type ATPase (CDC48 subfamily) 35.80 1 19 19 56 7.609E7 40.81 35.80 19 28 2814.69 35.80 19 28 743 81.9 4.82 HVO_1097 diaminopimelate epimerase 35.76 1 6 6 25 1.013E8 32.75 35.76 6 12 1669.11 35.76 6 13 288 29.9 4.48 HVO_2721 amidophosphoribosyltransferase 35.70 1 10 10 49 5.907E8 52.23 35.70 10 25 3428.39 35.70 10 24 493 53.4 4.78 HVO_0175 DNA polymerase sliding clamp 35.63 1 7 7 69 2.059E9 51.73 35.63 7 35 4014.77 35.63 6 34 247 26.7 4.39 HVO_1284 GTP cyclohydrolase III 35.63 1 7 7 34 2.047E8 31.20 35.63 7 17 2040.30 35.63 7 17 261 28.9 4.70 HVO_0350 DNA-directed RNA polymerase subunit A'' 35.56 1 14 14 68 1.136E9 65.75 30.07 13 34 4681.39 35.56 14 34 419 46.1 4.35 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 35.56 1 8 8 40 2.364E8 31.87 35.56 8 20 2297.46 35.56 8 20 270 29.1 4.35 HVO_2643 NADPH:quinone reductase 35.55 1 8 8 46 1.381E8 22.55 35.55 8 23 2224.53 27.75 7 23 346 37.2 4.55 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 35.51 1 34 34 138 4.256E8 113.36 32.94 33 68 7859.09 35.51 34 70 1284 141.2 4.35 HVO_B0060 precorrin-4 C11-methyltransferase 35.48 1 5 5 18 1.495E8 12.30 35.48 5 9 1032.34 35.48 5 9 279 29.7 4.22 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 35.41 1 6 6 20 1.399E8 15.05 35.41 6 10 1220.58 25.90 5 10 305 32.7 4.56 HVO_1079 sulfate adenylyltransferase small subunit 35.38 1 8 8 26 3.974E8 24.08 35.38 8 13 1657.13 33.54 7 13 325 37.5 4.18 HVO_2536 CHP00300 family protein 35.34 1 9 9 30 1.551E8 17.19 35.34 9 15 1349.70 35.34 9 15 416 44.8 4.51 HVO_0549 2-keto-3-deoxygluconate kinase 35.31 1 9 10 41 4.022E8 29.30 31.56 9 19 2911.56 35.31 10 22 320 34.1 4.34 HVO_2040 NAD-dependent epimerase/dehydratase 35.29 1 5 9 52 7.492E8 56.36 29.74 8 26 3858.08 35.29 9 26 306 33.8 4.51 HVO_1125 cysteine--tRNA ligase 35.22 1 12 12 49 2.756E8 46.59 35.22 12 26 3081.45 32.19 11 23 494 55.2 4.56 HVO_1573 DNA gyrase subunit A 35.15 1 28 28 146 5.383E8 122.55 35.15 28 72 8074.15 34.45 27 74 862 94.8 4.56 HVO_0138 tyrosine--tRNA ligase 35.06 1 7 7 29 5.034E8 19.68 35.06 7 14 1432.84 35.06 7 15 328 36.1 4.34 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 35.01 1 6 6 26 1.723E8 19.56 35.01 6 13 1548.37 35.01 6 13 377 39.2 4.18 HVO_1816 dihydroorotase 34.97 1 10 10 42 1.477E8 42.52 34.97 10 21 2608.61 34.97 10 21 429 45.4 4.40 HVO_2333 conserved hypothetical protein 34.74 1 9 9 26 6.669E7 6.84 31.49 8 12 905.91 34.74 9 14 308 34.9 4.54 HVO_1025 acetyl-CoA C-acyltransferase 34.73 1 10 10 43 3.429E8 42.99 34.73 9 21 2990.16 34.73 10 22 383 40.7 4.56 HVO_0911 GTP-binding protein Drg 34.69 1 10 10 33 4.923E7 20.06 30.62 9 16 1894.28 34.69 10 17 369 40.5 4.81 HVO_1896 30S ribosomal protein S24e 34.65 1 3 3 6 3.256E7 0.00 34.65 3 3 117.36 34.65 3 3 101 11.6 4.68 HVO_2130 IclR family transcription regulator 34.56 1 8 8 40 9.915E7 19.12 30.51 7 15 2359.30 34.56 8 25 272 30.1 5.55 HVO_0729 inorganic pyrophosphatase 34.46 1 6 6 50 6.962E8 46.97 34.46 6 25 3154.58 34.46 6 25 177 20.4 4.16 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 34.46 1 7 7 30 1.925E8 30.67 34.46 7 15 1373.49 34.46 7 15 386 42.1 4.49 HVO_1508 acetolactate synthase large subunit 34.41 1 12 12 47 5.671E8 59.63 34.41 12 24 3309.82 29.13 11 23 587 62.3 4.36 HVO_2417 conserved hypothetical protein 34.36 1 5 5 26 2.108E8 22.29 34.36 5 13 1888.48 34.36 5 13 195 21.6 3.65 HVO_1018 RecJ domain protein 34.28 1 22 22 123 7.313E8 115.73 34.28 21 61 8280.82 34.28 22 62 633 69.8 4.58 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 34.04 1 5 5 25 1.922E8 16.12 34.04 5 12 1240.26 34.04 5 13 188 20.5 4.60 HVO_2008 archaeosine synthase 33.85 1 16 16 59 4.507E8 36.65 31.45 14 27 2943.46 33.85 16 32 585 64.9 4.81 HVO_1491 HAD superfamily hydrolase 33.82 1 12 12 49 9.100E7 36.39 33.82 12 24 2851.23 33.82 12 25 408 44.4 4.60 HVO_A0496 UspA domain protein 33.45 1 8 8 43 2.324E8 39.25 33.45 8 21 2490.29 33.45 8 22 290 31.4 4.60 HVO_1847 oligoendopeptidase PepF 33.39 1 13 13 43 1.159E8 31.18 29.05 12 21 2340.58 33.39 13 22 599 68.5 4.41 HVO_1164 HD family hydrolase 33.33 1 9 9 24 1.887E8 11.74 29.26 8 12 1412.36 33.33 8 12 270 29.8 4.87 HVO_0452 leucine--tRNA ligase 33.30 1 24 24 102 4.496E8 90.21 33.30 24 53 7318.27 32.88 23 49 958 109.5 4.37 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 33.26 1 10 10 25 1.031E8 12.37 33.26 10 13 1006.03 29.41 9 12 442 46.9 4.58 HVO_2153 probable copper-containing oxidoreductase 33.25 1 9 9 38 1.701E8 22.56 30.13 8 19 1921.78 33.25 9 19 385 42.1 5.82 HVO_2781 DNA-directed RNA polymerase subunit D 33.20 1 7 7 39 6.733E8 36.82 28.96 6 18 3472.26 33.20 7 21 259 28.1 4.32 HVO_1250 redoxin domain protein 33.16 1 3 3 6 3.949E7 3.27 27.27 2 2 410.69 33.16 3 4 187 20.5 4.03 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 33.14 1 8 8 29 8.701E7 21.14 24.13 6 13 1964.29 33.14 8 16 344 39.1 4.73 HVO_1496 phosphotransferase system component I 33.10 1 14 14 63 5.214E8 67.69 33.10 14 32 4804.22 33.10 14 31 565 60.3 4.21 HVO_1570 DNA topoisomerase VI subunit A 33.06 1 9 9 30 3.054E8 17.57 30.33 8 14 1684.81 33.06 9 16 366 41.8 4.63 40354192 keratin 10 [Homo sapiens] 33.05 1 0 19 69 4.115E8 55.85 33.05 19 34 4151.55 33.05 19 35 584 58.8 5.16 HVO_1547 isoleucine--tRNA ligase 32.98 1 23 23 143 9.049E8 126.06 32.98 23 72 7882.23 32.98 23 71 1043 117.9 4.30 HVO_0694 probable phosphoribosyltransferase 32.91 1 6 6 14 2.860E7 11.81 24.47 5 7 706.86 32.91 6 7 237 27.0 4.32 HVO_0997 peptidase M24 family protein 32.88 1 7 7 27 1.262E8 23.37 32.88 7 13 1758.77 32.88 7 14 368 39.9 4.49 HVO_0658 tRNA pseudouridine(13) synthase TruD 32.83 1 10 10 37 1.233E8 35.20 32.83 10 18 2140.83 32.83 10 19 463 50.6 4.70 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 32.77 1 9 9 53 6.818E8 62.67 32.77 9 27 3919.73 32.77 9 26 415 44.4 4.41 HVO_A0547 DUF1028 family protein 32.73 1 8 8 24 1.568E8 18.57 32.73 8 12 1338.83 32.73 8 12 333 35.2 4.16 HVO_2913 superoxide dismutase (Mn) 32.66 1 0 4 15 9.709E8 19.14 32.66 4 8 1243.08 15.58 3 7 199 22.3 4.48 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 32.60 1 9 9 39 2.687E8 44.44 32.60 9 20 2808.13 28.63 8 19 454 48.5 4.46 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 32.55 1 0 19 69 4.115E8 55.85 32.55 19 34 4151.55 32.55 19 35 593 59.5 5.21 HVO_A0475 superoxide dismutase (Mn) 32.50 1 0 4 15 9.709E8 19.14 32.50 4 8 1243.08 15.50 3 7 200 22.4 4.45 HVO_0552 DNA mismatch repair protein MutS 32.47 1 22 22 65 1.735E8 54.05 29.44 20 32 3946.40 30.09 21 33 924 99.2 4.65 HVO_1500 1-phosphofructokinase 32.46 1 7 7 21 6.500E7 9.20 32.46 7 12 764.38 23.28 6 9 305 32.0 4.51 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 32.41 1 6 6 25 4.289E8 14.86 27.67 5 11 1411.95 32.41 6 14 253 26.0 4.60 HVO_1198 UspA domain protein 32.41 1 4 4 12 2.219E8 6.94 32.41 4 6 723.96 32.41 4 6 145 15.6 4.75 HVO_0017 conserved hypothetical protein 32.29 1 3 3 11 1.327E7 3.74 32.29 3 4 530.65 32.29 3 7 192 21.9 4.50 HVO_1867 lysine--tRNA ligase 32.25 1 14 15 59 2.459E8 60.29 30.63 13 28 3764.83 32.25 15 31 555 62.1 4.46 HVO_2496 adenylate kinase 32.21 1 7 7 34 7.571E8 43.51 32.21 7 17 2435.92 32.21 7 17 208 23.1 4.25 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 32.08 1 14 14 60 2.132E8 48.13 32.08 14 30 3396.27 32.08 14 30 586 63.4 4.70 HVO_A0331 D-galactonate dehydratase 31.77 1 7 7 31 1.038E8 25.72 31.77 7 15 1704.29 31.77 7 16 384 42.8 4.83 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 31.69 1 3 3 14 1.828E8 7.93 31.69 3 7 724.17 31.69 3 7 183 20.0 4.21 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 31.48 1 5 5 22 3.410E8 28.44 31.48 5 11 2187.23 31.48 5 11 324 33.6 3.99 HVO_1187 conserved hypothetical protein 31.47 1 4 4 6 1.610E7 2.02 31.47 4 4 151.85 17.48 2 2 143 16.4 4.86 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 20 1.062E9 18.78 31.45 3 10 1496.71 31.45 3 10 124 14.2 5.22 7428712 "keratin 1, type II, cytoskeletal - human" 31.42 1 0 20 141 8.334E8 147.38 31.42 20 70 9635.38 31.42 20 71 643 65.5 6.35 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 31.40 1 10 10 45 1.867E8 32.12 31.40 10 23 2173.82 31.40 10 22 430 45.1 4.50 HVO_1348 probable YjeF family carbohydrate kinase 31.38 1 11 11 47 1.698E8 43.82 31.38 11 23 3006.31 31.38 11 24 478 48.8 4.45 HVO_0853 DNA double-strand break repair protein Mre11 31.29 1 9 9 29 1.287E8 25.29 31.29 9 15 1284.46 31.29 9 14 441 48.1 4.39 HVO_0854 DNA double-strand break repair ATPase Rad50 31.24 1 22 22 73 1.144E8 60.22 28.78 21 36 4456.07 30.35 21 37 893 100.0 4.58 HVO_0048 argininosuccinate lyase 31.15 1 11 11 40 1.291E8 41.21 31.15 11 20 3089.14 31.15 11 20 488 50.8 4.53 HVO_1048 phosphoribosylformylglycinamidine synthase 2 31.05 1 14 14 77 7.742E8 99.36 30.06 13 38 6383.65 26.35 13 39 702 72.9 4.18 HVO_0601 homoserine dehydrogenase 31.01 1 5 5 34 3.632E8 48.87 31.01 5 16 3091.50 31.01 5 18 316 32.2 4.25 HVO_0697 PAC2 family protein 30.98 1 4 4 22 1.624E8 28.78 30.98 4 11 1738.49 30.98 4 11 255 27.4 4.08 HVO_0310 A-type ATP synthase subunit H 30.91 1 2 2 4 1.013E8 6.72 30.91 2 4 110 12.5 4.03 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 30.91 1 9 9 28 1.753E8 11.78 30.91 9 14 1352.77 28.57 8 14 427 45.4 4.56 HVO_B0371 aldehyde dehydrogenase 30.65 1 7 7 24 6.283E7 26.55 30.65 7 12 1745.45 30.65 7 12 496 52.5 4.39 HVO_B0375 Spo0M family protein 30.61 1 5 5 15 4.422E7 13.89 30.61 5 8 792.89 30.61 5 7 245 27.2 4.35 HVO_0292 replication protein A 30.55 1 8 8 28 2.229E8 36.58 30.55 8 14 2437.04 30.55 8 14 311 34.6 4.31 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 30.54 1 12 12 135 8.740E8 121.02 30.54 12 68 8622.14 30.54 12 67 370 41.9 4.48 HVO_0541 aconitate hydratase 30.49 1 20 20 60 2.348E8 22.15 29.42 19 29 2551.18 30.49 20 31 938 102.1 4.40 HVO_B0001 Orc1-type DNA replication protein 30.49 1 9 9 20 6.999E7 12.35 24.63 7 9 787.47 30.49 9 11 410 45.8 5.33 HVO_0889 FAD-dependent oxidoreductase 30.37 1 4 4 16 1.320E8 15.21 30.37 4 8 1195.61 30.37 4 8 214 21.8 3.89 HVO_1932 2-D-hydroxyacid dehydrogenase 30.19 1 8 8 34 1.721E8 31.54 30.19 8 18 2080.45 30.19 8 16 308 33.0 4.60 HVO_0042 acetylornithine deacetylase 30.18 1 8 8 19 2.468E8 15.38 27.82 7 9 1071.98 22.05 7 10 381 41.0 4.34 HVO_0795 transcription initiation factor TFB 30.15 1 6 10 28 1.475E8 27.07 25.37 8 13 1841.72 30.15 10 15 335 37.4 5.59 HVO_0044 acetylglutamate kinase 29.97 1 6 6 16 2.091E8 10.35 15.60 4 7 899.22 29.97 6 9 327 33.2 4.49 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 29.95 1 9 9 48 2.515E8 53.07 29.95 9 24 3974.27 29.95 9 24 364 39.3 4.35 HVO_C0069 GFO family oxidoreductase 29.94 1 8 8 43 1.044E8 36.22 29.94 8 22 2263.19 29.94 8 21 324 36.0 5.10 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 29.84 1 21 22 102 7.888E8 67.36 28.26 21 50 6711.32 29.84 22 52 697 74.5 4.13 HVO_A0266 IclR family transcription regulator 29.80 1 6 6 14 5.290E7 12.01 27.06 5 6 872.22 29.80 6 8 255 27.7 6.05 HVO_1858 30S ribosomal protein S19e 29.80 1 2 2 2 1.803E7 120.91 29.80 2 2 151 16.7 4.84 HVO_1465 naphthoate synthase 29.51 1 6 6 25 1.114E8 29.05 27.21 5 12 2063.08 29.51 6 13 305 33.9 4.83 HVO_2790 ATP-binding protein Mrp 29.48 1 6 6 22 1.686E8 32.30 29.48 6 11 1806.65 29.48 6 11 346 36.8 4.50 HVO_1488 D-gluconate dehydratase 29.37 1 8 10 96 8.096E8 89.70 29.37 10 49 6181.61 29.37 10 47 412 45.8 4.60 HVO_0894 acyl-CoA synthetase 29.31 1 7 14 42 1.787E8 33.52 26.13 12 20 2702.70 29.31 14 22 662 74.3 4.48 HVO_C0077 sarcosine oxidase 29.20 1 6 6 18 5.973E7 19.33 29.20 6 9 1224.30 29.20 6 9 387 42.9 4.70 HVO_1020 HEAT-PBS family protein 29.12 1 9 9 32 1.693E8 27.62 24.82 8 15 2896.33 29.12 9 17 419 45.5 3.95 HVO_3014 origin-associated GTP-binding protein OapA 29.11 1 6 6 15 4.335E7 7.44 29.11 6 8 749.29 29.11 6 7 213 24.0 5.01 HVO_0511 NAD-dependent epimerase/dehydratase 29.01 1 6 6 21 5.451E7 10.59 15.65 3 9 907.70 29.01 6 12 262 29.3 4.78 HVO_1553 hydroxypyruvate reductase 28.96 1 9 9 36 1.317E8 25.92 28.96 9 18 1898.00 28.96 9 18 442 45.2 4.50 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 28.84 1 24 24 129 5.125E8 142.90 27.36 23 64 10028.13 27.91 23 65 1082 117.2 4.32 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 28.84 1 5 7 18 3.986E7 10.94 22.47 6 9 848.59 23.97 6 9 267 28.8 4.55 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 28.82 1 9 9 56 4.731E8 50.28 21.33 7 27 3709.08 28.82 9 29 347 36.8 4.93 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 28.68 1 6 6 26 4.646E7 21.07 28.68 6 13 2010.55 28.68 6 13 265 29.3 4.92 HVO_B0066 Lrp/AsnC family transcription regulator 28.66 1 3 3 8 2.062E7 10.88 28.66 3 4 534.00 28.66 3 4 164 18.5 4.41 HVO_2951 tryptophan--tRNA ligase 28.54 1 13 13 40 1.183E8 24.76 26.84 12 20 1492.92 25.14 12 20 529 59.1 4.53 HVO_2707 GFO family oxidoreductase 28.49 1 9 9 30 2.160E8 30.76 28.49 9 16 2109.83 22.58 7 14 372 41.0 4.55 HVO_2706 translation initiation factor aIF-2B delta subunit 28.37 1 7 7 32 2.173E8 22.32 28.37 7 16 1802.43 28.37 7 16 282 30.7 4.42 HVO_2912 ThiJ/PfpI domain protein 28.36 1 3 3 11 3.586E7 14.01 28.36 3 6 645.80 28.36 3 5 201 20.9 4.36 HVO_1698 CBS/parB domain protein 28.30 1 5 6 10 2.684E7 4.07 21.51 5 5 522.08 26.42 5 5 265 29.4 4.92 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 28.23 1 8 8 32 1.230E8 29.25 28.23 8 16 2252.24 28.23 8 16 333 36.7 4.56 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 28.16 1 4 4 9 1.842E8 9.11 24.19 3 4 620.80 18.77 3 5 277 30.6 4.30 HVO_2879 ornithine cyclodeaminase 28.01 1 6 6 28 2.951E8 24.07 20.48 5 12 1888.40 28.01 6 16 332 34.6 4.45 HVO_2708 YfiH family protein 27.95 1 5 5 24 3.464E8 31.54 27.95 5 12 2222.19 27.95 5 12 322 35.4 4.35 HVO_1660 DisA-N domain protein 27.88 1 6 6 22 1.474E8 17.78 27.88 6 11 1660.96 27.88 6 11 269 28.9 4.73 HVO_2716 acyl-CoA dehydrogenase 27.82 1 8 8 24 5.988E7 21.87 25.46 7 12 1392.36 26.25 7 12 381 41.3 4.65 HVO_1391 NUDIX family hydrolase 27.81 1 4 4 16 4.444E7 10.23 27.81 4 8 939.26 27.81 4 8 151 17.4 5.01 HVO_0681 DNA topoisomerase I 27.74 1 18 18 55 1.357E8 50.53 25.71 16 26 3812.29 27.74 18 29 840 93.6 4.58 HVO_2256 DUF262 family protein 27.71 1 12 12 38 1.341E8 31.81 27.71 12 20 2076.14 23.59 10 18 462 54.9 4.89 HVO_A0307 Lrp/AsnC family transcription regulator 27.68 1 4 4 11 3.769E7 7.42 27.68 4 5 508.54 27.68 4 6 177 19.4 4.39 HVO_1087 UspA domain protein 27.66 1 4 4 13 4.955E7 12.24 27.66 4 6 944.70 27.66 4 7 141 15.2 4.98 HVO_1527 glucose-1-phosphate uridylyltransferase 27.57 1 6 6 32 2.671E8 25.76 27.57 6 15 1928.06 27.57 6 17 243 27.5 4.70 HVO_1871 UPF0447 family protein 27.35 1 12 12 69 3.098E8 51.79 23.95 11 33 3858.14 27.35 12 36 501 56.1 4.59 HVO_0466 citrate (si)-synthase 27.18 1 9 9 54 4.730E8 71.01 27.18 9 27 4099.96 27.18 9 27 379 41.8 4.55 HVO_0573 endonuclease IV 27.15 1 5 5 28 5.544E8 31.38 27.15 5 14 2399.34 27.15 5 14 291 31.4 4.44 HVO_1576 NAD-dependent epimerase/dehydratase 27.12 1 4 8 38 4.925E8 37.85 25.49 7 19 2739.66 27.12 8 19 306 33.9 4.51 HVO_1356 sensor box histidine kinase 27.09 1 10 10 28 9.708E7 13.79 27.09 10 14 1111.19 27.09 10 14 550 61.1 4.60 HVO_2662 homolog to lactoylglutathione lyase 27.05 1 6 6 19 1.059E8 15.77 27.05 6 10 1004.26 27.05 6 9 329 36.5 4.48 HVO_0879 DUF371 family protein 26.95 1 3 3 10 4.590E7 1.97 26.95 3 5 508.31 26.95 3 5 141 15.3 4.65 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 26.92 1 4 4 23 9.676E7 21.69 26.92 4 12 1679.90 26.92 4 11 208 22.6 4.36 HVO_1654 cysteine synthase 26.80 1 7 7 26 1.595E8 19.06 26.80 7 13 1459.65 26.80 7 13 306 32.3 4.32 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 26.77 1 4 4 16 9.696E7 12.83 26.77 4 8 881.42 26.77 4 8 269 28.3 4.49 HVO_A0350 conserved hypothetical protein 26.76 1 6 6 14 6.830E7 10.37 22.07 5 7 755.43 23.94 5 7 213 23.8 9.64 HVO_A0133 conserved hypothetical protein 26.71 1 6 6 18 1.003E8 13.43 25.00 5 9 1045.29 21.23 5 9 292 30.8 5.17 HVO_2580 L-aspartate oxidase 26.63 1 11 11 43 1.359E8 40.09 26.63 11 22 2773.22 26.63 11 21 537 55.8 4.63 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 26.41 1 7 7 24 9.316E7 26.08 26.41 7 12 1837.88 26.41 7 12 337 35.9 4.69 HVO_2784 30S ribosomal protein S13 26.35 1 4 4 9 7.782E7 4.45 26.35 4 5 398.63 26.35 4 4 167 18.9 5.17 HVO_0699 translation initiation factor aIF-2 alpha subunit 26.32 1 7 7 28 2.264E8 29.60 23.31 6 13 1879.42 26.32 7 15 266 29.5 4.46 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 26.30 1 8 8 21 1.176E8 8.23 23.01 7 9 1143.47 26.30 8 12 365 39.0 4.61 HVO_1098 diaminopimelate decarboxylase 26.27 1 7 7 22 1.758E8 12.38 26.27 7 11 942.72 26.27 7 11 415 44.4 5.02 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 26.11 1 7 7 18 5.094E7 18.11 26.11 7 10 1181.66 16.01 5 8 406 43.1 4.60 HVO_C0046 conserved hypothetical protein 26.09 1 0 3 6 1.075E7 2.46 26.09 3 3 230.59 26.09 3 3 184 20.1 4.42 HVO_C0081 conserved hypothetical protein 26.09 1 0 3 6 1.075E7 2.46 26.09 3 3 230.59 26.09 3 3 184 20.2 4.40 HVO_2547 50S ribosomal protein L32e 25.96 1 4 4 15 9.726E7 15.72 18.72 3 7 1207.68 25.96 4 8 235 25.8 4.75 HVO_1129 conserved hypothetical protein 25.90 1 6 6 17 1.112E8 17.78 23.85 5 8 1121.02 25.90 6 9 390 43.0 4.44 HVO_0358 homoserine dehydrogenase 25.87 1 6 7 35 2.417E8 32.83 25.87 7 17 2355.53 25.87 7 18 317 32.4 4.44 HVO_0868 NAD-dependent epimerase/dehydratase 25.84 1 8 8 22 5.379E7 7.41 25.84 8 12 903.21 21.88 7 10 329 36.1 4.55 HVO_1481 UspA domain protein 25.77 1 3 3 7 4.491E7 9.02 25.77 3 4 410.19 19.63 2 3 163 17.7 4.40 HVO_1503 3-isopropylmalate dehydratase small subunit 25.74 1 4 4 16 1.928E8 12.98 25.74 4 8 693.98 25.74 4 8 202 22.0 4.15 HVO_2481 HD family hydrolase 25.64 1 9 9 20 6.265E7 7.67 25.64 9 10 783.38 25.64 9 10 390 42.7 6.14 HVO_A0485 aminotransferase class V 25.64 1 6 6 26 1.290E8 28.74 25.64 6 13 1768.58 25.64 6 13 351 37.3 4.26 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 25.62 1 7 7 24 5.503E7 19.03 25.62 7 12 1634.63 25.62 7 12 324 36.6 4.68 HVO_1412 diphosphomevalonate decarboxylase 25.62 1 8 8 35 6.619E8 21.38 25.62 8 18 1875.26 25.62 8 17 324 35.4 4.78 HVO_A0465 TetR family transcription regulator 25.24 1 3 3 5 1.435E7 5.27 12.86 2 2 382.01 25.24 3 3 210 23.7 4.48 HVO_2313 siroheme decarboxylase AhbB 25.21 1 6 6 22 2.122E8 24.84 25.21 6 11 1551.86 25.21 6 11 353 39.6 4.64 HVO_2688 TrmB family transcription regulator 25.21 1 8 8 28 4.576E8 31.62 25.21 8 15 2402.27 22.66 7 13 353 39.3 4.58 HVO_A0021 conserved hypothetical protein 25.19 1 3 3 6 2.992E7 2.30 19.08 2 2 276.53 25.19 3 4 131 14.9 4.42 >sp|TRYP_PIG| 25.11 1 4 4 75 1.803E10 95.24 25.11 4 37 6222.96 25.11 4 38 231 24.4 7.18 HVO_B0018 ParA domain protein 25.09 1 3 3 17 7.785E7 19.87 25.09 3 9 1195.46 25.09 3 8 287 31.7 4.74 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 25.08 1 5 5 17 2.067E8 14.81 25.08 5 9 1048.73 11.37 4 8 299 32.0 4.53 HVO_1574 NUDIX family hydrolase 25.00 1 3 3 6 1.373E7 4.09 25.00 3 3 326.09 25.00 3 3 156 17.6 4.98 HVO_2425 GNAT family acetyltransferase 25.00 1 4 4 15 1.740E8 14.10 25.00 4 7 919.51 25.00 4 8 216 24.4 4.54 HVO_B0052 PQQ repeat protein 25.00 1 10 10 21 5.280E7 10.14 23.06 9 10 1065.18 23.06 9 11 412 44.1 5.48 HVO_0916 diphthine synthase 24.91 1 5 5 20 1.619E8 17.88 24.91 5 10 1183.57 24.91 5 10 269 29.1 4.54 HVO_2923 proteasome alpha subunit 24.90 1 5 6 17 1.810E8 13.47 24.90 6 9 1030.02 20.88 5 8 249 26.7 4.39 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 24.72 1 6 6 27 3.826E8 18.68 22.78 5 12 1331.46 24.72 6 15 360 38.5 4.45 HVO_1495 "phosphotransferase system component IIB, fructose-specific" 24.68 1 2 2 2 1.529E7 145.99 24.68 2 2 158 16.3 4.46 HVO_0970 ribulose-bisphosphate carboxylase large subunit 24.64 1 9 9 42 1.689E8 45.86 24.64 9 21 2972.64 24.64 9 21 414 43.9 4.59 HVO_A0156 acyl-CoA synthetase 24.55 1 4 11 31 1.787E8 20.01 21.39 9 15 1733.97 18.98 10 16 664 74.0 4.40 HVO_1866 uridylate kinase 24.47 1 4 4 18 3.551E8 15.46 24.47 4 9 1316.80 24.47 4 9 237 24.6 4.42 HVO_0536 ferritin 24.43 1 2 2 12 5.266E7 23.51 24.43 2 6 895.73 24.43 2 6 176 19.9 4.50 HVO_0123 signal recognition particle 54K protein 24.30 1 11 11 39 2.347E8 37.85 22.15 10 19 2659.17 23.01 10 20 465 50.9 4.50 HVO_2156 UspA domain protein 24.25 1 6 6 22 2.291E8 23.47 24.25 6 11 1798.78 24.25 6 11 301 31.6 4.69 HVO_1711 glucoamylase 24.22 1 29 29 98 1.196E8 71.43 24.22 29 49 5211.80 24.22 29 49 1511 166.1 4.64 HVO_2001 tRNA-guanine(15) transglycosylase 24.22 1 8 8 27 1.579E8 28.13 23.06 7 13 1828.76 24.22 8 14 516 56.3 4.59 HVO_1593 PAC2 family protein 24.19 1 3 3 8 1.263E8 12.73 24.19 3 4 497.81 24.19 3 4 248 26.6 4.46 HVO_2562 50S ribosomal protein L23 24.10 1 2 2 4 1.057E7 3.82 24.10 2 2 317.86 24.10 2 2 83 9.4 5.48 HVO_A0003 ParA domain protein 24.09 1 5 5 14 1.915E7 12.54 24.09 5 7 791.28 24.09 5 7 274 30.3 4.53 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 24.05 1 7 7 24 8.726E7 26.89 24.05 7 12 1923.96 24.05 7 12 420 45.0 4.86 HVO_0233 ribose-phosphate pyrophosphokinase 24.03 1 5 5 14 1.035E8 10.05 24.03 5 7 979.91 24.03 5 7 283 29.6 4.40 HVO_1382 nascent polypeptide-associated complex protein 24.03 1 2 2 6 4.178E7 9.08 24.03 2 3 572.48 24.03 2 3 129 13.7 4.06 HVO_1478 transcription initiation factor TFB 23.97 1 5 7 38 2.658E8 32.88 23.97 7 19 2551.34 23.97 7 19 317 35.7 5.47 HVO_0769 TRAM domain protein 23.88 1 3 3 6 2.032E7 5.93 23.88 3 3 379.39 23.88 3 3 134 14.8 4.32 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 23.88 1 7 7 18 9.878E7 11.05 14.96 5 7 792.37 23.88 7 11 381 40.5 4.51 HVO_2960 dihydrolipoamide S-acyltransferase 23.80 1 11 11 36 1.822E8 23.71 23.80 11 19 2083.01 22.46 10 17 521 54.9 4.40 HVO_1575 arginase 23.75 1 5 5 18 1.919E8 14.09 23.75 5 9 977.35 23.75 5 9 299 31.0 4.58 HVO_2168 AAA-type ATPase (MoxR subfamily) 23.71 1 5 5 15 6.360E7 11.99 20.97 4 7 697.71 23.71 5 8 329 35.9 4.54 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 23.53 1 0 3 9 2.934E8 1.96 23.53 3 4 447.39 23.53 3 5 85 10.0 5.94 HVO_1918 probable metallo-beta-lactamase family hydrolase 23.51 1 3 3 12 3.389E7 11.34 23.51 3 6 869.63 23.51 3 6 302 34.0 4.55 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 23.45 1 5 5 14 7.388E7 5.94 23.45 5 7 605.87 11.86 4 7 388 41.9 4.35 HVO_2543 50S ribosomal protein L30 23.38 1 2 2 5 3.219E7 0.00 23.38 2 3 86.45 23.38 2 2 154 17.1 4.77 HVO_0357 ACT domain protein 23.28 1 3 4 13 1.477E8 14.41 23.28 4 7 930.91 20.11 3 6 189 20.2 4.59 HVO_C0001 Orc1-type DNA replication protein 23.28 1 9 9 26 9.022E7 17.96 21.57 8 13 1286.81 23.28 9 13 408 45.2 4.97 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 23.25 1 6 6 30 3.565E8 20.86 23.25 6 15 1619.19 23.25 6 15 357 39.8 4.41 HVO_0818 threonine synthase 23.14 1 8 8 29 2.699E8 19.09 21.08 7 15 1446.99 23.14 8 14 389 40.8 4.31 HVO_0214 L-lactate dehydrogenase 23.13 1 8 8 38 7.932E8 30.68 23.13 8 19 2377.01 23.13 8 19 320 34.5 4.49 HVO_1344 SBDS family protein 23.11 1 4 4 16 3.328E7 13.31 23.11 4 8 868.59 23.11 4 8 238 26.5 4.51 HVO_0179 Lrp/AsnC family transcription regulator / TrkA domain protein 22.99 1 4 5 9 2.974E7 2.62 22.99 5 5 260.84 20.69 4 4 261 28.0 4.58 HVO_2205 arNOG06768 family NADH-binding domain protein 22.92 1 5 5 15 2.805E7 11.07 22.92 5 8 815.40 22.92 5 7 301 32.0 5.00 HVO_1783 conserved hypothetical protein 22.77 1 3 3 10 2.402E7 12.76 22.77 3 5 695.53 22.77 3 5 224 24.1 5.90 HVO_0484 50S ribosomal protein L10e 22.73 1 3 3 12 4.569E7 17.81 22.73 3 6 713.27 22.73 3 6 176 19.8 8.72 HVO_1459 ThuA family protein 22.69 1 3 3 12 2.005E8 21.32 22.69 3 6 1147.23 22.69 3 6 238 26.8 4.67 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 22.69 1 7 7 62 1.204E9 66.14 22.69 7 31 3861.13 22.69 7 31 357 40.3 4.40 HVO_2945 valine--tRNA ligase 22.64 1 16 16 62 4.726E8 57.69 21.15 15 30 4290.30 18.62 15 32 870 98.9 4.36 HVO_2712 3'-5' RNA ligase 22.63 1 10 10 36 1.359E8 20.47 22.63 10 18 1744.59 22.63 10 18 486 53.4 4.92 HVO_0360 30S ribosomal protein S10 22.55 1 2 2 8 8.743E7 10.17 22.55 2 4 628.04 22.55 2 4 102 11.5 4.88 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 22.54 1 10 10 33 9.193E7 23.28 22.54 10 18 1877.87 21.33 9 15 661 71.0 4.35 HVO_1510 2-isopropylmalate synthase 22.50 1 7 7 37 9.662E8 37.41 20.91 6 18 2593.20 22.50 7 19 440 47.7 4.82 HVO_1579 uridine phosphorylase 22.43 1 3 3 6 6.748E7 7.31 22.43 3 3 323.12 22.43 3 3 272 29.0 4.64 HVO_2266 hypothetical protein 22.31 1 8 8 34 1.772E8 31.34 17.04 7 16 2320.54 22.31 8 18 493 56.7 4.54 HVO_B0115 fumarylacetoacetase family protein 22.26 1 5 5 17 1.171E8 23.04 22.26 5 9 1295.48 20.49 4 8 283 30.3 4.21 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 22.22 1 9 9 35 2.354E8 36.85 20.33 7 16 2148.60 22.22 9 19 423 43.9 4.31 HVO_1880 conserved hypothetical protein 22.22 1 4 4 10 1.823E7 10.04 22.22 4 5 661.81 22.22 4 5 225 23.8 4.59 HVO_1989 tRNA (pseudouridine(54)-N(1))-methyltransferase 22.22 1 2 2 7 2.977E7 8.84 22.22 2 3 442.90 22.22 2 4 198 21.9 4.79 HVO_2793 conserved hypothetical protein 22.22 1 4 4 14 5.094E7 13.78 22.22 4 7 888.37 22.22 4 7 252 27.1 4.46 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 22.09 1 9 9 23 6.315E7 15.39 22.09 9 12 1164.70 20.54 8 11 516 56.7 4.89 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 22.04 1 10 10 32 9.436E7 28.40 19.00 9 15 2059.41 22.04 10 17 658 72.1 4.70 HVO_1337 rpa-associated protein 21.99 1 9 9 34 5.167E8 38.40 21.99 9 17 2352.13 21.03 8 17 623 64.8 3.68 HVO_1804 nicotinate phosphoribosyltransferase 21.91 1 7 7 21 1.750E8 23.59 18.81 6 10 1817.45 19.59 6 11 388 41.1 4.60 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 21.83 1 6 6 20 1.434E8 15.74 21.83 6 10 1213.11 21.83 6 10 339 38.1 4.50 HVO_0354 30S ribosomal protein S7 21.57 1 4 4 16 1.932E8 12.29 21.57 4 8 1063.13 21.57 4 8 204 22.6 5.14 HVO_B0057 precorrin-3B C17-methyltransferase 21.51 1 4 4 30 3.892E8 31.83 21.51 4 15 2153.23 21.51 4 15 344 36.3 4.31 HVO_1914 acetyl-CoA C-acyltransferase 21.49 1 6 6 21 7.184E7 7.78 18.83 5 10 1003.19 21.49 6 11 377 39.9 4.41 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 21.45 1 6 6 29 3.837E8 19.18 21.45 6 14 1511.26 21.45 6 15 373 40.2 4.44 HVO_1453 glutamate dehydrogenase (NADP) 21.34 1 7 7 26 1.140E8 16.87 21.34 7 13 1376.45 21.34 7 13 417 45.7 4.49 HVO_1625 conserved hypothetical protein 21.25 1 10 10 25 9.599E7 29.88 19.72 9 12 2025.91 21.25 10 13 654 70.1 4.04 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 21.16 1 6 6 24 9.681E7 21.55 21.16 6 12 1382.45 21.16 6 12 345 36.9 4.68 HVO_0001 Orc1-type DNA replication protein 21.10 1 10 10 27 4.009E7 22.18 18.97 9 13 1772.28 21.10 10 14 564 62.1 4.39 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 21.09 1 2 2 8 8.959E7 11.17 21.09 2 4 758.72 21.09 2 4 128 13.0 4.31 HVO_1291 fumarylacetoacetase family protein 20.99 1 3 3 9 3.736E8 8.41 20.99 3 5 568.83 20.99 3 4 243 26.3 4.55 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 20.96 1 7 7 18 4.576E7 7.24 20.96 7 10 693.29 16.40 6 8 439 47.2 4.59 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 20.88 1 2 2 8 2.200E7 1.81 20.88 2 4 247.46 20.88 2 4 91 10.4 4.07 HVO_2888 homolog to elongator complex protein ELP3 20.73 1 9 9 26 1.394E8 16.31 20.73 9 13 1413.14 20.73 9 13 550 62.6 5.01 HVO_2761 mevalonate kinase 20.71 1 5 5 22 7.357E7 24.81 20.71 5 11 1285.13 20.71 5 11 367 38.2 4.31 HVO_0826 peptidase M42 family protein 20.69 1 4 4 16 4.355E7 15.46 20.69 4 8 1074.26 20.69 4 8 348 37.7 4.54 HVO_A0476 conserved hypothetical protein 20.54 1 4 4 10 2.743E7 5.73 20.54 4 5 458.80 20.54 4 5 331 35.4 4.26 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 20.49 1 6 6 16 3.109E7 6.88 20.49 6 8 816.93 20.49 6 8 327 36.0 4.73 HVO_0180 23S rRNA (uridine-2'-O-) methyltransferase 20.46 1 4 4 11 4.723E7 4.74 16.22 3 5 442.49 20.46 4 6 259 28.3 4.70 HVO_1175 DUF2110 family protein 20.44 1 4 4 20 4.157E8 30.25 20.44 4 10 1679.76 20.44 4 10 225 24.4 4.63 HVO_A0498 conserved hypothetical protein 20.32 1 6 6 14 5.954E7 5.41 16.62 5 6 906.40 20.32 6 8 379 42.7 4.55 HVO_1827 30S ribosomal protein S6e 20.30 1 2 2 6 1.323E7 6.83 20.30 2 3 376.47 20.30 2 3 133 13.9 4.32 HVO_B0382 TATA-binding transcription initiation factor 20.21 1 3 3 9 3.405E7 10.95 20.21 3 5 642.06 20.21 3 4 188 20.1 4.12 HVO_0441 probable metallo-beta-lactamase family hydrolase 20.19 1 2 2 3 2.878E7 0.00 20.19 2 3 208 22.7 4.51 HVO_2227 siroheme decarboxylase AhbA 20.17 1 5 5 15 4.806E7 6.57 20.17 5 8 649.89 17.87 4 7 347 39.1 4.69 HVO_B0058 precorrin-3B C17-methyltransferase 20.07 1 4 4 11 4.270E7 10.52 20.07 4 6 669.72 17.01 3 5 294 31.8 4.40 HVO_2648 phosphoglycerate dehydrogenase 20.06 1 5 5 15 6.670E7 7.45 17.24 4 7 825.66 20.06 5 8 319 34.2 4.64 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 20.06 1 6 6 26 9.848E7 25.40 20.06 6 13 1573.44 20.06 6 13 349 37.0 4.70 HVO_2187 CHP01210 family protein 20.00 1 5 5 13 3.203E7 9.78 10.83 4 6 770.69 20.00 5 7 360 40.0 4.58 HVO_2702 alpha/beta hydrolase fold protein 20.00 1 4 4 16 4.950E7 4.43 20.00 4 8 721.25 20.00 4 8 260 28.0 4.53 HVO_2158 malic enzyme (NADP) 19.97 1 5 9 43 1.593E8 29.81 19.97 9 21 1828.89 19.97 9 22 751 81.4 4.55 HVO_2636 PspA domain protein 19.93 1 6 6 16 2.911E7 11.59 19.93 6 8 1054.04 19.93 6 8 276 30.9 4.61 HVO_1727 TATA-binding transcription initiation factor 19.89 1 4 4 25 5.810E8 20.12 19.89 4 12 1878.36 19.89 4 13 186 19.9 4.36 HVO_2918 thymidylate synthase 19.88 1 3 3 12 8.025E7 18.62 19.88 3 6 1120.46 19.88 3 6 332 37.5 4.61 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 19.84 1 6 6 21 1.449E8 20.05 17.49 5 11 1199.07 19.84 6 10 383 42.0 4.49 HVO_B0114 IclR family transcription regulator 19.84 1 5 5 12 1.905E7 11.40 19.84 5 6 626.65 19.84 5 6 252 28.4 5.44 HVO_0220 ATP-dependent DNA helicase MCM 19.80 1 12 12 37 4.165E7 27.76 19.80 12 19 2083.82 16.95 11 18 702 78.8 4.73 HVO_1704 homolog to arabinopyranose mutase 19.74 1 5 5 15 4.188E7 13.39 14.55 4 7 1002.22 19.74 5 8 385 43.4 4.23 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 19.71 1 13 13 36 6.868E7 23.89 18.71 12 18 1705.91 19.71 13 18 898 97.7 4.45 HVO_0977 N5-carboxyaminoimidazole ribonucleotide mutase 19.70 1 2 2 3 1.531E7 2.47 19.70 2 3 203 21.5 4.36 HVO_0402 DUF124 family protein 19.56 1 3 3 5 7.314E7 0.00 8.89 2 2 119.74 19.56 3 3 225 24.0 4.58 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 19.51 1 4 4 8 3.684E7 5.98 19.51 4 4 421.56 19.51 4 4 287 31.8 4.93 HVO_1657 phosphoribosylamine--glycine ligase 19.39 1 8 8 62 9.267E8 47.45 19.39 8 30 3665.14 19.39 8 32 428 45.5 4.20 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 31 1.204E9 22.63 19.31 5 15 2082.49 19.31 5 16 378 39.7 4.67 HVO_2600 methionyl aminopeptidase 19.26 1 7 7 21 3.482E8 15.72 15.20 6 10 1422.54 17.23 6 11 296 32.3 4.41 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 19.16 1 4 4 14 1.042E8 6.84 19.16 4 7 489.07 19.16 4 7 261 27.0 4.44 HVO_2427 replication factor C large subunit 19.06 1 8 8 30 6.057E7 31.96 19.06 8 15 2019.25 19.06 8 15 488 53.4 4.67 HVO_0054 glycine--tRNA ligase 19.02 1 6 6 25 1.170E9 39.67 16.67 5 12 2679.29 14.14 5 13 594 64.9 4.21 HVO_A0439 DUF2800 family protein 19.02 1 3 4 9 2.974E7 5.29 19.02 4 4 372.73 19.02 4 5 326 36.9 4.51 HVO_1485 conserved hypothetical protein 18.96 1 2 2 2 1.646E7 94.26 18.96 2 2 211 23.0 4.42 HVO_1289 OsmC domain protein 18.94 1 2 2 34 8.298E8 47.52 18.94 2 17 3540.47 18.94 2 17 132 14.2 3.85 HVO_0034 acyl-CoA thioester hydrolase 18.90 1 3 3 35 1.583E8 30.02 18.90 3 17 2377.50 18.90 3 18 164 18.3 4.65 HVO_2952 tRNA-splicing endonuclease 18.88 1 5 5 11 2.629E7 9.52 18.88 5 6 593.10 15.34 4 5 339 37.4 4.74 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 18.80 1 21 21 58 9.821E7 37.22 16.48 19 28 2534.37 18.80 21 30 1335 150.5 4.60 HVO_1568 alpha/beta hydrolase fold protein 18.77 1 4 4 14 2.857E7 9.43 18.77 4 8 681.13 7.94 2 6 277 29.4 4.94 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 18.74 1 8 8 22 8.119E7 13.74 17.21 7 11 1293.27 16.78 7 11 459 50.5 4.63 HVO_2503 kynureninase 18.59 1 6 6 11 3.550E7 2.01 15.76 5 5 512.92 18.59 6 6 425 46.0 4.54 HVO_2763 homolog to ribonuclease Z 18.55 1 4 4 16 3.376E7 10.23 18.55 4 8 547.34 18.55 4 8 248 26.6 4.53 HVO_1354 DNA mismatch repair protein MutS 18.45 1 9 9 20 5.375E7 5.35 15.34 8 10 896.13 16.21 8 10 580 62.1 4.56 HVO_A0486 hydrogenase expression/formation protein 18.45 1 4 4 14 5.867E7 17.89 18.45 4 7 1045.52 18.45 4 7 336 33.8 4.06 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 18.43 1 0 10 31 3.129E8 22.37 18.43 10 15 1592.35 18.43 10 16 472 51.6 5.16 HVO_A0388 Lrp/AsnC family transcription regulator 18.39 1 3 3 5 1.833E7 2.56 10.34 2 2 277.82 18.39 3 3 174 20.1 4.86 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 18.30 1 8 8 32 1.099E8 33.10 18.30 8 16 2214.11 18.30 8 16 634 66.1 4.54 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 21 2.279E8 20.40 18.29 4 10 1815.75 18.29 4 11 257 26.8 4.01 HVO_0989 conserved hypothetical protein 18.25 1 2 2 8 3.842E7 0.00 18.25 2 4 276.95 18.25 2 4 126 14.4 4.81 HVO_1375 O-succinylbenzoic acid--CoA ligase 18.08 1 7 7 19 4.348E7 17.30 13.19 6 9 833.36 18.08 7 10 614 64.7 4.28 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 17.99 1 3 3 12 8.128E7 6.44 17.99 3 6 554.93 17.99 3 6 189 21.7 4.46 HVO_2548 50S ribosomal protein L6 17.98 1 2 2 6 2.473E7 7.42 17.98 2 3 493.63 17.98 2 3 178 19.6 4.68 HVO_0429 archaemetzincin 17.92 1 2 2 8 5.508E7 3.14 17.92 2 4 413.48 17.92 2 4 173 19.3 6.54 HVO_2421 probable DNA-binding protein 17.87 1 2 2 4 2.055E7 0.00 17.87 2 2 101.37 17.87 2 2 235 25.8 4.89 HVO_1073 ThiJ/PfpI family protein 17.86 1 3 3 10 5.382E7 1.81 17.86 3 5 388.57 17.86 3 5 224 23.9 4.12 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 17.86 1 4 4 16 2.156E8 23.12 17.86 4 8 1409.46 17.86 4 8 252 26.0 4.39 HVO_0712 shikimate dehydrogenase (nonfunctional) 17.84 1 3 3 8 2.653E7 5.07 17.84 3 4 331.32 17.84 3 4 269 27.7 4.65 HVO_0867 HD family hydrolase 17.83 1 4 4 12 6.162E7 8.38 17.83 4 6 643.66 17.83 4 6 230 26.2 4.78 HVO_0120 signal recognition particle receptor FtsY 17.76 1 7 7 21 5.934E7 19.62 17.76 7 11 1498.72 17.32 6 10 456 48.2 4.17 HVO_1878 NAD synthase 17.75 1 5 5 30 1.723E8 25.23 17.75 5 15 1940.16 17.75 5 15 276 29.6 4.37 HVO_0493 HTH domain protein 17.69 1 2 2 6 2.726E7 6.31 17.69 2 3 306.83 17.69 2 3 130 14.1 4.79 HVO_2965 phosphoserine phosphatase 17.67 1 2 2 6 3.269E7 6.20 17.67 2 3 374.03 17.67 2 3 215 23.2 4.51 HVO_2581 quinolinate synthase A 17.66 1 6 6 23 1.374E8 13.75 17.66 6 12 1056.48 15.32 5 11 385 42.0 4.41 HVO_1578 probable NADH dehydrogenase 17.63 1 4 4 12 4.739E7 10.19 17.63 4 6 563.37 17.63 4 6 397 42.8 4.40 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 17.57 1 11 11 25 6.581E7 15.14 15.54 9 12 1115.52 16.35 10 13 740 85.6 4.70 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 17.49 1 4 4 14 5.422E7 20.14 17.49 4 7 1169.05 17.49 4 7 446 47.9 4.39 HVO_0670 glutathione S-transferase 17.48 1 5 5 11 2.206E7 9.22 12.58 4 5 862.96 17.48 5 6 326 38.1 4.56 HVO_2873 flap endonuclease Fen1 17.48 1 4 4 9 4.840E7 9.26 17.48 4 5 721.75 9.51 3 4 326 36.4 4.40 HVO_2564 50S ribosomal protein L3 17.46 1 4 4 7 3.607E7 8.87 17.46 4 4 631.73 13.31 3 3 338 37.2 6.68 HVO_1595 conserved hypothetical protein 17.42 1 2 2 8 3.638E7 2.30 17.42 2 4 207.05 17.42 2 4 178 20.2 4.74 HVO_1083 glucose 1-dehydrogenase 17.37 1 4 4 8 4.497E7 4.79 9.52 2 3 378.92 17.37 4 5 357 39.0 4.73 HVO_1792 Lrp/AsnC family transcription regulator 17.28 1 2 2 6 4.031E7 4.03 17.28 2 3 267.69 17.28 2 3 162 18.1 4.34 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 17.24 1 3 3 14 1.061E8 9.16 17.24 3 7 668.08 17.24 3 7 348 36.7 4.69 HVO_1710 alpha amylase 17.13 1 11 11 38 1.747E8 21.85 17.13 11 20 2002.52 12.85 9 18 677 75.0 4.45 HVO_0401 UspA domain protein 17.11 1 2 2 8 1.602E8 11.42 17.11 2 4 634.28 17.11 2 4 152 16.4 4.79 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 17.05 1 5 5 11 2.547E7 10.62 12.84 4 5 671.20 17.05 5 6 475 49.3 4.49 HVO_1139 squalene synthase 17.04 1 4 4 12 1.122E8 11.73 14.80 3 5 685.99 17.04 4 7 358 39.7 4.54 HVO_A0328 2-keto-3-deoxygluconate kinase 16.98 1 3 4 12 1.883E8 8.94 16.98 4 6 562.82 16.98 4 6 318 34.0 4.60 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 16.91 1 7 7 38 2.267E8 39.81 16.91 7 18 2335.77 16.91 7 20 615 67.6 4.88 HVO_2467 NADPH:quinone reductase 16.82 1 4 4 18 1.064E8 16.04 16.82 4 9 1159.03 16.82 4 9 321 33.0 4.51 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 16.75 1 5 5 16 4.147E7 11.84 16.75 5 8 794.41 16.75 5 8 406 45.5 5.08 HVO_0304 electron transfer flavoprotein alpha subunit 16.72 1 3 3 11 6.109E7 15.67 13.56 2 4 1338.08 16.72 3 7 317 33.5 4.18 HVO_1058 TrkA domain protein 16.63 1 6 6 18 7.558E7 9.74 16.63 6 9 840.78 16.63 6 9 445 47.7 4.35 HVO_2998 homoserine O-acetyltransferase 16.63 1 4 4 7 4.026E7 6.87 16.63 4 4 341.56 12.77 3 3 415 44.8 4.69 HVO_3000 DNA ligase (NAD) 16.60 1 9 9 24 1.775E8 26.81 16.60 9 12 1612.63 16.60 9 12 699 75.8 4.50 HVO_B0055 conserved hypothetical protein 16.44 1 5 5 20 2.147E8 14.37 16.44 5 10 934.62 16.44 5 10 225 23.9 4.69 HVO_1656 YyaL family protein 16.36 1 9 9 24 5.277E7 10.67 14.51 8 12 991.46 15.22 8 12 703 77.3 4.49 HVO_B0117 conserved hypothetical protein 16.35 1 3 3 8 3.722E7 9.42 16.35 3 4 695.83 16.35 3 4 208 23.3 4.58 HVO_2072 S-layer glycoprotein 16.32 1 6 6 60 1.630E9 59.21 16.32 6 33 2710.51 16.32 6 27 827 85.1 3.65 HVO_B0324 conserved hypothetical protein 16.26 1 5 5 12 3.542E7 8.38 16.26 5 6 563.41 16.26 5 6 449 48.0 4.58 HVO_0508 conserved hypothetical protein 16.22 1 2 2 8 1.025E7 10.94 16.22 2 4 522.01 16.22 2 4 148 16.0 3.92 HVO_1741 conserved hypothetical protein 16.16 1 3 3 7 6.145E6 1.96 4.88 2 3 212.54 16.16 3 4 328 37.6 4.46 HVO_2782 30S ribosomal protein S11 16.15 1 2 2 8 2.675E7 4.73 16.15 2 4 432.01 16.15 2 4 130 13.4 8.56 HVO_1746 DUF2800 family protein 16.10 1 3 4 10 3.802E7 1.97 16.10 4 5 295.47 16.10 4 5 323 36.5 4.37 HVO_2255 conserved hypothetical protein 16.10 1 2 2 4 2.632E7 2.56 16.10 2 2 132.80 16.10 2 2 236 27.7 5.60 HVO_1864 molybdopterin synthase catalytic subunit 16.09 1 4 4 12 4.449E7 10.74 16.09 4 6 513.16 16.09 4 6 261 27.9 4.41 HVO_0837 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 16.05 1 3 3 8 1.265E7 7.43 16.05 3 4 496.18 16.05 3 4 243 24.8 4.48 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 16.00 1 3 3 12 5.235E7 4.05 16.00 3 6 473.55 16.00 3 6 175 18.8 4.63 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 15.83 1 4 4 22 6.056E7 21.63 15.83 4 11 1435.89 15.83 4 11 360 39.5 4.31 HVO_1567 conserved hypothetical protein 15.74 1 3 3 8 9.113E7 2.80 15.74 3 4 301.56 15.74 3 4 235 25.7 4.36 HVO_C0042 helicase domain protein 15.70 1 17 17 47 8.342E7 41.56 14.21 16 23 3016.49 15.70 17 24 1274 144.4 4.67 HVO_1979 tRNA pseudouridine synthase Pus10 15.69 1 6 6 34 3.196E8 24.14 15.69 6 18 1884.42 15.69 6 16 427 46.9 4.39 HVO_0491 FMN-binding domain protein 15.69 1 2 2 2 1.428E7 86.76 15.69 2 2 153 17.3 4.67 HVO_1373 acyl-CoA dehydrogenase 15.67 1 4 4 12 5.335E7 12.21 15.67 4 6 806.61 15.67 4 6 383 42.5 4.61 HVO_0741 DNA-directed DNA polymerase X 15.64 1 5 5 10 2.596E7 0.00 15.64 5 6 233.27 9.11 3 4 582 62.6 4.44 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 15.61 1 3 3 6 7.713E7 4.42 15.61 3 3 383.87 15.61 3 3 237 25.4 4.46 HVO_A0273 ThuA family protein 15.61 1 2 2 2 2.225E7 0.00 15.61 2 2 237 26.5 4.77 HVO_1323 "shikimate kinase, archaeal-type" 15.57 1 3 3 13 1.403E8 17.61 15.57 3 7 1016.70 9.00 2 6 289 29.5 4.30 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 15.53 1 3 3 13 5.269E7 17.75 10.50 2 6 1109.72 15.53 3 7 219 22.4 4.06 HVO_2412 Lrp/AsnC family transcription regulator 15.53 1 2 2 6 3.799E7 3.88 15.53 2 3 141.79 15.53 2 3 161 17.7 4.55 HVO_1629 conserved hypothetical protein 15.44 1 8 8 26 4.408E7 18.89 15.44 8 14 1255.89 13.94 7 12 531 56.3 4.69 HVO_2068 "FtsZ family protein, type III" 15.41 1 3 3 10 1.220E8 14.17 15.41 3 5 1135.31 15.41 3 5 370 38.7 4.49 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 15.38 1 5 5 33 1.494E8 36.95 13.15 4 16 2202.67 15.38 5 17 403 41.1 4.73 HVO_A0087 fumarylacetoacetase family protein 15.22 1 3 3 14 1.486E8 19.32 15.22 3 7 1095.17 15.22 3 7 289 32.0 4.21 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 15.18 1 2 2 9 4.244E7 0.00 15.18 2 4 225.22 15.18 2 5 336 36.0 4.51 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 15.15 1 5 5 14 7.037E7 8.81 15.15 5 8 516.77 13.28 4 6 482 50.6 4.31 HVO_2229 flavin-containing amine-oxidoreductase 15.12 1 4 4 14 3.885E7 4.97 15.12 4 7 491.51 15.12 4 7 344 37.9 4.92 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 15.08 1 4 4 18 5.512E7 8.65 15.08 4 9 879.78 15.08 4 9 305 34.1 4.91 HVO_1895 KEOPS complex subunit Kae1/Bud32 15.04 1 6 6 19 8.079E7 20.45 11.59 5 9 1020.28 15.04 6 10 552 59.0 5.07 HVO_A0158 acyl-CoA synthetase 14.92 1 3 6 16 9.227E7 4.09 11.69 5 7 621.03 14.92 6 9 650 71.2 4.63 HVO_1501 DeoR family transcription regulator GlpR 14.90 1 3 3 10 2.212E7 7.64 14.90 3 5 512.96 14.90 3 5 255 28.0 4.97 HVO_0768 radical SAM domain protein 14.87 1 5 5 12 3.711E7 7.49 9.20 3 5 354.31 14.87 5 7 565 62.0 4.84 HVO_A0228 5'-nucleotidase SurE 14.78 1 2 2 8 4.338E7 11.41 14.78 2 4 618.63 14.78 2 4 291 31.5 4.59 HVO_2321 bacterial-type DNA primase DnaG 14.62 1 4 4 9 2.795E7 5.47 14.62 4 5 418.56 9.96 3 4 472 49.4 4.36 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 14.59 1 4 4 11 8.538E7 10.66 14.59 4 5 660.66 14.59 4 6 329 36.3 4.49 HVO_1683 4-alpha-glucanotransferase 14.52 1 6 6 16 5.539E7 5.33 14.52 6 9 435.23 12.70 5 7 496 56.3 4.45 HVO_2373 30S ribosomal protein S8e 14.40 1 2 2 5 5.387E7 1.69 14.40 2 2 169.34 14.40 2 3 125 13.6 10.48 HVO_0069 sulfatase 14.37 1 6 6 16 4.095E7 5.97 14.37 6 8 719.73 14.37 6 8 515 57.4 4.35 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 14.29 1 2 2 4 5.641E7 1.89 14.29 2 2 92.52 14.29 2 2 238 24.7 4.15 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 14.24 1 3 3 7 4.104E7 4.03 5.64 2 3 362.49 14.24 3 4 337 35.9 4.39 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 14.18 1 3 3 10 1.839E7 10.35 14.18 3 5 629.09 14.18 3 5 268 27.9 4.87 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 14.12 1 0 7 19 3.048E8 13.06 14.12 7 9 932.57 14.12 7 10 432 48.1 5.02 HVO_2239 UspA domain protein 14.08 1 2 2 2 2.422E7 165.83 14.08 2 2 142 15.4 4.16 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 13.99 1 4 4 10 3.123E7 9.73 13.99 4 5 635.88 13.99 4 5 386 41.3 4.46 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 13.91 1 3 3 10 6.888E7 7.57 13.91 3 5 623.89 13.91 3 5 266 29.7 4.32 HVO_0194 Orc1-type DNA replication protein 13.90 1 6 6 16 2.166E7 6.23 13.90 6 8 459.30 13.90 6 8 374 42.2 4.94 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 13.89 1 4 4 22 1.365E8 15.90 13.89 4 11 1055.50 13.89 4 11 612 67.3 4.16 HVO_2502 hydrogenase expression/formation protein 13.87 1 2 2 4 1.116E7 1.82 13.87 2 2 84.13 13.87 2 2 346 36.0 4.31 HVO_0469 AstE family protein 13.84 1 3 3 7 6.774E7 8.11 8.18 2 3 456.67 13.84 3 4 318 33.9 5.85 HVO_2758 50S ribosomal protein L11 13.84 1 2 2 3 1.356E8 477.56 13.84 2 3 159 16.8 4.04 HVO_C0044 PLD domain protein 13.81 1 3 3 5 1.727E7 2.08 7.51 2 2 220.46 13.81 3 3 333 36.4 4.94 HVO_2639 DUF1611 family protein 13.78 1 4 4 32 1.154E8 34.31 13.78 4 16 2168.55 13.78 4 16 341 36.3 4.44 HVO_1228 halocyanin 13.76 1 9 9 33 9.690E7 27.74 13.76 9 17 1844.59 13.76 9 16 821 83.7 4.17 HVO_B0149 oleate hydratase 13.70 1 5 6 15 9.626E7 13.60 10.51 5 7 676.55 13.70 6 8 533 60.1 4.64 HVO_0470 threonine synthase 13.62 1 3 3 9 2.876E7 3.78 13.62 3 5 265.26 8.45 2 4 367 39.2 4.59 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 13.58 1 4 4 24 1.156E8 20.94 13.58 4 12 1390.18 13.58 4 12 464 53.1 4.54 HVO_1407 HTH domain protein 13.33 1 2 2 8 4.619E7 2.20 13.33 2 4 360.51 13.33 2 4 225 24.9 4.45 HVO_0797 conserved hypothetical protein 13.29 1 2 2 4 1.843E7 0.00 13.29 2 2 165.33 13.29 2 2 173 17.6 4.44 HVO_2908 dihydropteroate synthase 13.19 1 4 4 11 3.825E7 8.15 13.19 4 6 386.72 13.19 4 5 379 40.8 4.53 HVO_1562 proteasome beta subunit 13.17 1 3 3 20 5.338E7 18.19 13.17 3 10 1288.86 13.17 3 10 243 26.0 4.63 HVO_1140 acyl-CoA dehydrogenase 13.16 1 5 5 12 3.171E7 7.68 13.16 5 6 614.11 13.16 5 6 380 41.2 4.55 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 13.16 1 4 4 13 6.939E7 6.80 9.62 3 5 853.96 13.16 4 8 395 42.4 4.54 HVO_1936 F420-0:gamma-glutamyl ligase 13.15 1 3 3 8 2.611E7 2.07 13.15 3 4 263.78 13.15 3 4 251 27.4 4.68 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 13.08 1 2 2 7 3.386E7 0.00 13.08 2 4 101.68 13.08 2 3 237 26.2 4.70 HVO_2108 IclR family transcription regulator 13.04 1 2 2 3 1.778E7 2.01 13.04 2 3 253 28.0 5.74 HVO_0600 ACT domain protein 12.99 1 2 2 8 5.035E7 4.74 12.99 2 4 469.14 12.99 2 4 177 19.2 4.44 HVO_0591 L-threonine-O-3-phosphate decarboxylase 12.94 1 2 2 2 5.273E7 61.85 12.94 2 2 340 36.0 4.54 HVO_1077 diphthamide biosynthesis protein Dph6 12.92 1 2 2 6 3.164E7 8.41 12.92 2 3 683.82 12.92 2 3 240 26.0 4.15 HVO_1380 methylmalonyl-CoA mutase subunit A 12.90 1 5 5 12 2.539E7 2.81 11.83 4 6 394.58 11.47 4 6 558 61.9 4.41 HVO_A0586 sugar nucleotidyltransferase 12.90 1 4 4 14 5.088E7 12.25 12.90 4 7 963.30 12.90 4 7 411 43.7 4.69 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 12.86 1 3 3 10 3.138E7 4.45 12.86 3 5 475.70 12.86 3 5 280 30.0 4.92 HVO_B0200 malate synthase 12.84 1 3 3 12 1.796E8 16.18 12.84 3 6 1014.92 12.84 3 6 436 48.3 4.30 HVO_1055 TrkA domain protein 12.83 1 3 3 7 1.302E7 2.79 12.83 3 4 269.96 9.29 2 3 226 24.4 4.39 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 12.70 1 4 4 16 5.846E7 12.16 12.70 4 8 831.25 12.70 4 8 378 39.8 4.45 HVO_1268 conserved hypothetical protein 12.66 1 2 2 8 1.771E7 5.98 12.66 2 4 334.19 12.66 2 4 237 26.4 5.21 HVO_2160 conserved hypothetical protein 12.63 1 18 18 114 8.789E8 143.64 12.63 18 57 10430.36 12.63 18 57 2257 232.7 3.92 HVO_1446 "fructose-1,6-bisphosphatase" 12.46 1 2 2 3 1.437E7 466.21 12.46 2 3 297 31.6 4.45 HVO_0014 ATP-dependent DNA helicase Hel308a 12.45 1 8 9 29 7.374E7 22.13 12.45 9 15 1693.06 12.45 9 14 827 90.3 4.67 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 12.38 1 3 3 10 2.296E7 8.81 12.38 3 5 552.82 12.38 3 5 323 34.9 5.24 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 12.26 1 0 7 23 3.129E8 13.21 12.26 7 11 1249.03 12.26 7 12 473 51.2 5.05 HVO_1148 30S ribosomal protein S15 12.26 1 2 2 4 2.177E7 2.40 12.26 2 2 222.69 12.26 2 2 155 17.5 4.91 HVO_2297 deoxyhypusine synthase 12.26 1 2 2 6 5.838E7 2.84 12.26 2 3 131.34 12.26 2 3 359 38.6 4.59 HVO_1723 DNA repair helicase Rad25 12.23 1 7 7 21 3.856E7 17.42 9.78 6 10 1243.83 12.23 7 11 695 76.8 4.69 HVO_1879 enoyl-CoA hydratase 12.12 1 2 2 4 1.092E7 2.26 12.12 2 2 223.30 12.12 2 2 231 24.3 5.21 HVO_A0012 hypothetical protein 12.08 1 2 2 8 3.328E7 1.78 12.08 2 4 320.56 12.08 2 4 149 17.7 4.54 HVO_A0092 acyl-CoA dehydrogenase 12.07 1 4 4 10 1.714E7 3.84 12.07 4 5 491.81 12.07 4 5 381 42.2 4.83 HVO_B0101 IclR family transcription regulator 12.06 1 3 3 8 1.742E7 5.10 12.06 3 4 388.59 12.06 3 4 257 28.6 5.02 HVO_B0182 deoxyhypusine synthase 12.04 1 3 3 11 7.971E7 6.61 12.04 3 6 488.03 12.04 3 5 324 35.6 4.30 HVO_1457 conserved hypothetical protein 12.03 1 2 2 2 1.608E7 63.87 12.03 2 2 291 32.8 4.40 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 11.99 1 2 3 10 2.994E7 4.47 11.99 3 5 444.66 11.99 3 5 267 29.1 4.63 HVO_2485 biotin--[acetyl-CoA-carboxylase] ligase 11.98 1 2 2 8 4.593E7 5.84 11.98 2 4 576.80 11.98 2 4 334 35.7 4.75 HVO_1174 transcription initiation factor TFE 11.93 1 2 2 3 3.155E7 248.95 11.93 2 3 176 20.6 4.23 HVO_1893 non-canonical purine NTP pyrophosphatase 11.90 1 2 2 8 1.398E7 6.33 11.90 2 4 477.89 11.90 2 4 210 23.0 4.58 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 11.89 1 3 3 6 3.165E7 0.00 11.89 3 3 82.45 11.89 3 3 328 36.1 4.67 HVO_2605 MiaB-like tRNA modifying enzyme 11.89 1 3 3 11 5.250E7 1.60 11.89 3 6 455.55 6.76 2 5 429 47.4 5.03 HVO_A0550 receiver/sensor box histidine kinase 11.75 1 9 9 23 3.421E7 15.36 10.28 8 11 1310.91 11.75 9 12 885 95.9 4.46 HVO_0228 ParA domain protein 11.74 1 2 2 5 2.035E8 400.56 11.74 2 5 247 24.6 4.16 HVO_1413 probable NADH dehydrogenase 11.67 1 4 4 8 2.095E7 6.41 11.67 4 4 379.16 11.67 4 4 377 39.7 4.67 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 10 1.778E8 6.36 11.64 2 5 575.27 11.64 2 5 189 20.3 4.22 HVO_A0230 peptide methionine sulfoxide reductase MsrA (S-form specific) 11.64 1 2 2 6 3.913E7 0.00 11.64 2 3 228.01 11.64 2 3 189 21.0 4.27 HVO_1299 HTH domain protein 11.56 1 2 2 4 9.969E6 1.70 11.56 2 2 131.98 11.56 2 2 173 18.9 4.84 HVO_1150 IS200-type transposase 11.54 1 2 2 9 1.899E7 3.08 11.54 2 4 359.83 11.54 2 5 130 14.7 5.49 HVO_0639 AAA-type ATPase (MoxR subfamily) 11.39 1 3 3 11 2.656E7 5.84 11.39 3 6 615.03 11.39 3 5 316 34.7 4.89 4557890 keratin 5 [Homo sapiens] 11.36 1 0 8 32 2.517E8 28.11 11.36 8 16 2058.05 11.36 8 16 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 11.36 1 0 8 32 2.517E8 28.11 11.36 8 16 2058.05 11.36 8 16 590 62.4 8.06 HVO_2383 DNA repair and recombination protein RadB 11.35 1 3 3 8 2.745E7 9.86 11.35 3 4 557.89 11.35 3 4 229 24.6 5.02 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 11.29 1 3 3 19 1.990E8 14.40 9.92 2 9 1406.02 11.29 3 10 363 39.7 4.25 HVO_1249 conserved hypothetical protein 11.27 1 2 2 4 1.577E7 1.65 11.27 2 2 74.13 11.27 2 2 142 16.4 5.20 HVO_2880 probable peptide chain release factor pelota 11.24 1 4 4 16 1.215E8 12.26 11.24 4 7 930.23 11.24 4 9 356 39.3 4.63 HVO_0569 RIO-type serine/threonine protein kinase 11.22 1 2 2 6 1.643E7 4.23 11.22 2 3 346.95 11.22 2 3 303 34.4 4.94 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 11.22 1 2 2 4 6.786E7 2.71 11.22 2 2 133.77 11.22 2 2 294 32.5 4.75 HVO_2456 anthranilate phosphoribosyltransferase 11.18 1 2 2 8 1.583E8 8.77 11.18 2 4 496.23 11.18 2 4 331 33.8 4.35 HVO_B0154 receiver/sensor box histidine kinase 11.07 1 10 10 30 4.367E7 17.28 11.07 10 15 1352.38 11.07 10 15 1301 144.1 4.39 HVO_B0277 HTH domain protein 11.07 1 2 2 2 1.237E7 0.00 11.07 2 2 262 29.5 4.50 HVO_A0551 acyl-CoA synthetase 10.97 1 5 5 18 2.886E7 18.09 10.97 5 9 1125.93 10.97 5 9 538 59.6 4.65 HVO_1340 "probable glycosyltransferase, type 1" 10.93 1 4 4 13 1.104E8 4.35 10.93 4 6 659.30 10.93 4 7 375 41.0 4.42 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 10.88 1 4 4 9 3.045E7 7.92 9.33 3 4 572.29 10.88 4 5 386 40.0 4.68 HVO_1374 acyl-CoA synthetase 10.85 1 5 5 17 6.437E7 10.12 10.85 5 8 1015.75 10.85 5 9 553 61.1 4.50 HVO_1470 isochorismate synthase 10.84 1 3 3 4 2.039E7 233.85 10.84 3 4 443 47.7 4.56 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 10.79 1 2 2 6 1.669E7 3.78 10.79 2 3 252.01 10.79 2 3 241 26.1 4.58 HVO_2504 probable oxidoreductase (short-chain dehydrogenase family) 10.78 1 2 2 4 7.330E6 0.00 10.78 2 2 217.38 10.78 2 2 232 24.8 4.59 HVO_2131 "fructose-1,6-bisphosphatase" 10.73 1 2 2 6 1.604E7 7.72 10.73 2 3 536.13 10.73 2 3 289 31.3 4.48 HVO_2082 conserved hypothetical protein 10.61 1 2 2 2 2.954E6 0.00 10.61 2 2 396 40.9 4.50 HVO_1008 GFO family oxidoreductase 10.54 1 3 3 10 3.190E7 6.54 10.54 3 5 577.99 10.54 3 5 332 36.0 4.72 HVO_0076 uroporphyrinogen-III synthase 10.53 1 2 2 4 1.721E7 2.18 10.53 2 2 124.81 10.53 2 2 247 25.5 4.30 HVO_1387 enoyl-CoA hydratase 10.51 1 2 2 4 2.311E7 1.74 10.51 2 2 106.04 10.51 2 2 257 27.5 4.51 HVO_B0026 probable oxidoreductase (short-chain dehydrogenase family) 10.51 1 2 2 3 3.507E7 161.65 10.51 2 3 257 26.7 4.55 HVO_0414 peptidase M24 family protein 10.47 1 2 2 6 3.196E7 4.01 10.47 2 3 272.02 10.47 2 3 382 39.4 4.82 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 10.42 1 0 5 22 2.324E8 18.40 10.42 5 11 1462.57 10.42 5 11 384 42.4 5.40 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 10.40 1 2 2 6 2.892E7 2.96 10.40 2 3 221.59 10.40 2 3 327 36.2 4.63 HVO_1685 conserved hypothetical protein 10.37 1 5 5 18 4.970E7 8.39 10.37 5 9 962.98 10.37 5 9 492 54.5 5.74 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 10.23 1 4 4 28 3.969E8 25.47 10.23 4 14 1663.85 10.23 4 14 430 44.2 4.37 HVO_B0183 YgeA family protein 10.20 1 3 3 6 8.017E7 1.76 6.53 2 3 214.25 10.20 3 3 245 26.8 4.58 HVO_0689 chromosome segregation protein Smc 10.16 1 11 11 29 3.681E7 19.37 9.44 10 14 1473.29 10.16 11 15 1240 138.1 4.39 HVO_0322 MinD/ParA domain protein 10.15 1 3 3 14 1.616E8 12.00 10.15 3 8 622.02 10.15 3 6 581 58.8 3.70 HVO_2350 YyaL family protein 10.14 1 4 4 9 7.222E7 3.43 9.24 3 4 513.91 10.14 4 5 552 58.8 4.59 HVO_A0561 formimidoylglutamase 10.13 1 2 2 4 6.805E6 2.31 10.13 2 2 165.31 10.13 2 2 316 32.8 4.55 21961227 Keratin 6B [Homo sapiens] 10.11 1 0 7 30 3.264E8 26.35 10.11 7 15 1950.40 10.11 7 15 564 60.0 8.00 HVO_0522 HdaI-type histone deacetylase 10.09 1 3 3 7 8.750E6 9.29 10.09 3 4 509.25 10.09 2 3 337 36.3 4.45 HVO_2852 succinylglutamate desuccinylase/aspartoacylase family protein 10.07 1 2 2 2 2.637E7 1.74 10.07 2 2 288 31.3 4.58 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 12 7.700E7 4.91 10.00 2 6 560.50 10.00 2 6 190 21.0 4.74 HVO_0719 transcription elongation factor Spt5/NusG 10.00 1 2 2 3 4.563E7 265.90 10.00 2 3 150 16.3 4.50 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 9.98 1 2 2 2 3.309E7 0.00 9.98 2 2 401 43.1 4.60 HVO_1309 peptidase M24 family protein 9.97 1 4 4 14 7.766E7 11.26 9.97 4 8 721.25 9.97 4 6 391 42.1 4.36 HVO_A0560 imidazolonepropionase 9.95 1 2 2 4 1.161E7 4.72 9.95 2 2 162.00 9.95 2 2 412 42.4 4.46 HVO_2614 uridine phosphorylase 9.92 1 3 3 16 4.088E8 17.59 9.92 3 8 1128.45 9.92 3 8 242 25.8 4.30 HVO_B0127 oxidoreductase (luciferase family protein) 9.78 1 2 2 6 6.520E7 4.44 9.78 2 3 181.11 9.78 2 3 317 35.7 4.60 HVO_0019 probable S-adenosylmethionine-dependent methyltransferase (homolog to 24-sterol C-methyltransferase) 9.73 1 2 2 9 2.152E7 8.32 9.73 2 4 437.77 9.73 2 5 226 25.6 4.64 HVO_0732 "ribonuclease H, type 1" 9.64 1 2 2 2 1.288E7 0.00 9.64 2 2 197 21.5 5.07 HVO_0476 conserved hypothetical protein 9.63 1 2 2 8 2.995E7 11.45 9.63 2 4 608.91 9.63 2 4 218 23.8 4.60 HVO_1287 PfpI family protease 9.60 1 2 2 6 1.425E7 3.32 9.60 2 3 213.10 9.60 2 3 198 21.5 4.53 HVO_1925 probable GTP-binding protein 9.54 1 2 2 2 5.218E7 0.00 9.54 2 2 325 36.5 4.72 HVO_2501 alpha/beta hydrolase fold protein 9.49 1 2 2 6 2.399E7 8.48 9.49 2 3 319.42 9.49 2 3 316 35.3 5.72 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 9.42 1 4 4 20 5.696E7 8.16 9.42 4 10 785.54 9.42 4 10 584 63.3 4.79 HVO_0190 TIGR00268 family protein 9.40 1 2 2 8 3.694E7 5.90 9.40 2 4 354.60 9.40 2 4 298 32.5 4.60 HVO_0968 NADH dehydrogenase-like complex subunit CD 9.40 1 1 5 20 1.452E8 17.10 9.04 4 10 1137.84 8.16 4 10 564 63.3 4.60 HVO_0675 pantoate kinase 9.39 1 2 2 2 2.726E7 1.61 9.39 2 2 277 27.8 4.54 HVO_1437 conserved hypothetical protein 9.36 1 2 2 7 1.797E7 4.47 9.36 2 4 263.93 9.36 2 3 203 22.3 4.94 HVO_2573 probable methenyltetrahydrofolate cyclohydrolase 9.35 1 2 2 8 4.772E7 12.39 9.35 2 4 788.30 9.35 2 4 310 32.7 3.92 HVO_1283 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase / threonine 3-dehydrogenase) 9.34 1 2 2 4 3.206E6 0.00 9.34 2 2 113.65 9.34 2 2 332 35.8 4.61 HVO_C0067 FAD-dependent oxidoreductase 9.34 1 2 2 10 7.730E7 8.48 9.34 2 5 649.41 9.34 2 5 396 42.7 4.30 HVO_0558 SAMP-activating enzyme E1 9.26 1 2 2 6 2.851E7 2.72 9.26 2 3 278.15 9.26 2 3 270 28.7 4.35 HVO_0507 creatininase 9.17 1 2 2 4 1.015E7 0.00 9.17 2 2 118.20 9.17 2 2 240 25.6 4.56 HVO_0787 indole-3-glycerol-phosphate synthase 9.16 1 2 2 4 2.230E7 3.51 9.16 2 2 175.95 9.16 2 2 251 26.7 4.44 HVO_2311 glutamyl-tRNA reductase 9.11 1 3 3 8 1.863E7 5.85 9.11 3 4 414.72 9.11 3 4 461 49.2 4.54 HVO_A0254 DUF234 domain protein 9.11 1 5 5 9 1.973E7 2.25 7.38 4 4 286.23 9.11 5 5 461 52.7 4.78 HVO_0572 lipoate-protein ligase 9.09 1 2 2 8 2.073E7 7.45 9.09 2 4 517.25 9.09 2 4 275 30.5 4.84 HVO_2932 GTP-binding protein 9.09 1 3 3 10 9.514E7 4.27 9.09 3 4 461.64 9.09 3 6 396 43.5 4.51 HVO_0029 UvrABC system protein B 9.03 1 4 4 14 4.212E7 9.86 9.03 4 7 840.36 9.03 4 7 698 79.0 4.45 HVO_0979 NADH dehydrogenase-like complex subunit B 9.01 1 2 2 8 4.831E7 5.57 9.01 2 4 421.96 9.01 2 4 233 26.1 5.01 HVO_B0345 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 8.99 1 2 2 4 3.683E7 1.74 8.99 2 2 94.13 8.99 2 2 378 41.2 4.84 HVO_0760 "probable glycosyltransferase, type 2" 8.97 1 3 3 10 2.584E7 3.59 8.97 3 5 419.11 8.97 3 5 368 40.7 4.82 HVO_B0025 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 8.96 1 2 2 3 1.395E7 283.75 8.96 2 3 346 37.2 4.53 HVO_0464 threonine ammonia-lyase 8.93 1 3 3 6 2.158E7 0.00 8.93 3 3 233.44 8.93 3 3 403 43.7 4.72 HVO_C0043 conserved hypothetical protein 8.93 1 4 4 10 2.495E7 5.44 8.93 4 5 383.58 8.93 4 5 661 73.8 4.75 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 8.90 1 3 3 10 5.313E7 6.30 8.90 3 5 567.39 8.90 3 5 438 46.4 4.58 HVO_1861 thiamine-monophosphate kinase 8.75 1 3 3 8 1.631E7 4.22 8.75 3 4 355.52 8.75 3 4 297 30.8 4.32 HVO_B0143 receiver/sensor box histidine kinase 8.71 1 4 4 10 3.457E7 12.04 8.71 4 5 773.10 8.71 4 5 597 66.0 4.41 HVO_0662 HTH domain protein / thiamine-phosphate synthase 8.70 1 3 3 8 2.668E7 2.31 8.70 3 4 365.22 8.70 3 4 299 31.9 4.44 HVO_0305 electron transfer flavoprotein beta subunit 8.68 1 2 2 5 5.476E7 0.00 8.68 2 3 111.43 8.68 2 2 265 28.5 4.04 HVO_1565 DNA ligase (ATP) 8.55 1 4 4 11 1.804E7 11.18 8.55 4 6 736.10 6.67 3 5 585 62.7 4.44 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 8.54 1 3 3 10 7.566E7 8.23 8.54 3 5 649.99 8.54 3 5 398 43.4 4.37 HVO_B0256 aldehyde ferredoxin oxidoreductase 8.47 1 3 3 3 1.656E7 4.27 8.47 3 3 555 59.9 4.55 HVO_1676 transcription initiation factor TFB 8.43 1 0 3 3 4.676E7 219.90 8.43 3 3 332 37.3 5.49 HVO_2071 conserved hypothetical protein 8.38 1 4 4 10 5.875E7 12.26 8.38 4 5 744.06 8.38 4 5 549 58.4 4.72 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 8.33 1 0 6 24 2.517E8 20.12 8.33 6 12 1530.78 8.33 6 12 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 8.33 1 0 6 24 2.517E8 20.12 8.33 6 12 1530.78 8.33 6 12 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 8.33 1 0 6 24 2.517E8 20.12 8.33 6 12 1530.78 8.33 6 12 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 8.33 1 0 6 24 2.517E8 20.12 8.33 6 12 1530.78 8.33 6 12 564 60.0 7.72 HVO_0687 M20 family amidohydrolase 8.33 1 4 4 10 1.969E7 8.65 8.33 4 5 664.40 8.33 4 5 444 47.5 4.58 HVO_1235 creatininase 8.33 1 2 2 8 4.031E7 2.98 8.33 2 4 420.54 8.33 2 4 264 29.2 4.84 HVO_1357 receiver/bat box HTH-10 family transcription regulator 8.25 1 4 4 10 2.987E7 7.12 8.25 4 5 426.16 8.25 4 5 582 62.7 4.40 HVO_B0038A D-xylonate dehydratase 8.25 1 1 3 20 4.350E8 17.44 8.25 3 10 1194.32 8.25 3 10 412 45.5 4.55 HVO_1716 7-cyano-7-deazaguanine synthase 8.20 1 2 2 2 4.943E7 0.00 8.20 2 2 244 26.8 4.42 HVO_1668 gamma-glutamylcysteine synthetase 8.10 1 3 3 6 6.879E6 4.97 8.10 3 3 321.10 8.10 3 3 358 39.9 4.72 HVO_0319 A-type ATP synthase subunit D 8.09 1 2 2 4 1.360E7 4.31 8.09 2 2 291.66 8.09 2 2 235 26.7 4.72 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 8.01 1 2 2 10 2.138E8 6.29 8.01 2 5 410.08 8.01 2 5 574 62.8 4.17 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 8.00 1 0 4 11 3.048E8 3.89 8.00 4 5 589.26 8.00 4 6 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 8.00 1 0 4 11 3.048E8 3.89 8.00 4 5 589.26 8.00 4 6 400 44.1 5.14 HVO_1117 HTH-10 family transcription regulator 7.98 1 2 2 6 8.823E6 4.40 7.98 2 3 322.89 7.98 2 3 213 23.3 4.56 HVO_1425 conserved hypothetical protein 7.92 1 2 2 8 2.613E7 3.94 7.92 2 4 250.56 7.92 2 4 265 30.4 4.61 HVO_0590 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase 7.89 1 2 2 6 2.744E7 4.67 7.89 2 3 368.38 7.89 2 3 355 35.6 4.30 HVO_2955 DEAD/DEAH box helicase 7.83 1 5 5 8 2.486E7 1.68 6.03 3 3 265.15 7.83 5 5 779 85.8 4.94 HVO_1052 transcription initiation factor TFB 7.83 1 0 3 4 6.403E7 366.82 7.83 3 4 332 37.3 5.25 HVO_2529 probable oxidoreductase (short-chain dehydrogenase family) 7.83 1 2 2 2 3.461E7 122.06 7.83 2 2 230 23.6 4.72 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 7.76 1 5 5 13 3.963E7 7.45 7.76 5 7 661.24 7.76 5 6 838 89.1 4.65 HVO_B0233 alpha-L-arabinofuranosidase 7.63 1 3 3 10 1.605E7 10.73 7.63 3 5 663.36 7.63 3 5 511 57.5 4.39 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 7.56 1 3 3 6 1.277E7 2.03 7.56 3 3 150.07 7.56 3 3 410 46.0 4.89 HVO_2665 HpcH/HpaI aldolase family protein 7.55 1 2 2 6 2.414E7 6.18 7.55 2 3 294.61 7.55 2 3 265 28.3 4.50 HVO_1128 sirohydrochlorin cobaltochelatase 7.53 1 2 2 6 4.567E7 2.14 7.53 2 3 273.78 7.53 2 3 292 32.3 4.42 HVO_1725 Orc1-type DNA replication protein 7.48 1 3 3 7 3.944E7 7.00 5.49 2 3 577.11 7.48 3 4 401 44.5 5.19 HVO_0195 ribose-5-phosphate isomerase 7.39 1 2 2 3 4.361E7 266.61 7.39 2 3 230 23.2 4.54 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 7.34 1 2 2 4 1.103E7 1.91 7.34 2 2 151.32 7.34 2 2 286 30.8 4.46 HVO_2004 serine O-acetyltransferase 7.32 1 1 2 12 6.104E8 3.33 7.32 2 6 479.69 7.32 2 6 287 31.9 5.21 HVO_1564 conserved hypothetical protein 7.27 1 3 3 8 1.648E7 4.80 7.27 3 4 336.59 7.27 3 4 509 56.5 4.65 HVO_0135 RIO-type serine/threonine protein kinase 7.24 1 2 2 6 2.956E7 4.46 7.24 2 3 478.25 7.24 2 3 290 33.0 4.81 HVO_B0257 4-aminobutyrate aminotransferase 7.19 1 2 2 3 1.145E7 308.92 7.19 2 3 459 49.3 4.92 HVO_0077 uroporphyrin-III C-methyltransferase 7.17 1 2 2 8 2.390E7 3.52 7.17 2 4 304.96 7.17 2 4 293 30.5 4.50 HVO_1615 conserved hypothetical protein 7.17 1 2 2 4 2.650E7 2.10 7.17 2 2 173.68 7.17 2 2 251 28.4 4.59 HVO_B0266 glutamate dehydrogenase (NAD) 7.13 1 3 3 6 1.334E7 2.25 7.13 3 3 164.45 7.13 3 3 435 47.3 4.63 HVO_1047 NADPH:quinone reductase 7.12 1 2 2 8 2.563E7 8.08 7.12 2 4 434.79 7.12 2 4 323 33.8 4.27 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 6 6.862E7 6.52 7.07 2 3 361.47 7.07 2 3 297 32.3 3.98 HVO_0716 D-tyrosyl-tRNA(Tyr) deacylase 7.06 1 2 2 6 8.917E6 6.43 7.06 2 3 600.98 7.06 2 3 439 46.7 4.48 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 7.02 1 0 4 11 3.048E8 3.89 7.02 4 5 589.26 7.02 4 6 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 7.02 1 0 4 11 3.048E8 3.89 7.02 4 5 589.26 7.02 4 6 456 49.2 4.77 HVO_1589 molecular chaperone DnaJ 7.01 1 2 3 3 1.258E7 135.43 7.01 3 3 385 41.9 4.97 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 7.00 1 2 2 6 1.378E7 6.74 7.00 2 3 357.33 7.00 2 3 400 44.2 4.32 HVO_B0202 sensor box protein 6.91 1 2 2 2 7.119E6 112.80 6.91 2 2 304 33.5 4.92 HVO_0724 ArsA family ATPase 6.85 1 2 2 6 1.775E7 6.06 6.85 2 3 222.46 6.85 2 3 409 43.9 4.22 HVO_1735 conserved hypothetical protein 6.82 1 4 4 10 1.368E7 5.29 6.82 4 5 498.68 6.82 4 5 660 75.7 4.50 31074631 keratin 1b [Homo sapiens] 6.75 1 0 4 16 3.245E8 8.20 6.75 4 8 906.73 6.75 4 8 578 61.8 5.97 HVO_0710 aminodeoxychorismate synthase component II 6.75 1 3 3 8 1.681E7 4.01 6.75 3 4 345.10 5.16 2 4 504 54.6 4.53 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 6.67 1 2 2 4 4.193E7 0.00 6.67 2 2 80.08 6.67 2 2 345 37.0 3.95 HVO_1313 probable S-adenosylmethionine-dependent methyltransferase 6.64 1 2 2 4 1.954E7 5.42 6.64 2 2 275.57 6.64 2 2 467 51.9 4.60 386849 keratin type II 6.57 1 0 4 10 1.580E8 12.31 6.57 4 5 772.25 6.57 4 5 563 59.9 7.94 HVO_0824 "probable glycosyltransferase, type 1" 6.53 1 2 2 8 7.496E6 8.87 6.53 2 4 474.99 6.53 2 4 352 39.6 5.08 HVO_2697 DNA primase small subunit 6.49 1 2 2 6 1.289E7 6.44 6.49 2 3 315.75 6.49 2 3 385 42.6 4.72 HVO_A0159 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 6.46 1 2 2 3 2.396E7 3.96 6.46 2 3 387 42.7 4.44 HVO_0431 HAD superfamily hydrolase 6.34 1 2 2 6 2.376E7 1.75 6.34 2 3 324.81 6.34 2 3 284 30.4 4.26 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 6.33 1 2 2 3 1.718E7 335.43 6.33 2 3 379 41.7 4.83 HVO_0475 conserved hypothetical protein 6.09 1 2 2 4 9.167E6 1.66 6.09 2 2 93.66 6.09 2 2 312 32.5 4.74 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 6.08 1 2 3 7 2.494E7 2.35 6.08 3 4 275.94 4.95 2 3 444 47.1 4.77 HVO_2479 2-phospho-L-lactate transferase 6.06 1 2 2 5 1.348E7 3.88 6.06 2 3 208.42 6.06 2 2 330 34.7 4.32 HVO_2058 NAD-dependent epimerase/dehydratase (homolog to dTDP-4-dehydrorhamnose reductase) 6.00 1 2 2 8 1.939E8 6.34 6.00 2 4 461.30 6.00 2 4 300 32.0 4.22 HVO_A0562 urocanate hydratase 5.97 1 3 3 7 1.640E7 7.81 3.87 2 3 336.43 5.97 3 4 620 67.9 4.70 HVO_2929 probable nucleoside deaminase (cytosine/guanine deaminase) 5.95 1 3 3 8 1.966E7 4.04 5.95 3 4 329.05 5.95 3 4 437 47.1 4.72 HVO_1812 conserved hypothetical protein 5.87 1 2 2 8 3.301E7 7.45 5.87 2 4 533.63 5.87 2 4 375 40.5 4.50 HVO_2263 conserved hypothetical protein 5.87 1 4 4 8 5.510E7 4.18 2.50 2 3 358.61 5.87 4 5 801 89.5 5.54 HVO_A0559 histidine ammonia-lyase 5.87 1 2 2 4 2.616E7 3.61 5.87 2 2 232.76 5.87 2 2 528 55.5 4.84 HVO_0733 transcription initiation factor TFB 5.83 1 0 2 6 2.688E8 2.52 5.83 2 3 306.43 5.83 2 3 326 37.2 6.00 HVO_A0150 TrmB family transcription regulator 5.65 1 2 2 4 9.488E7 2.57 5.65 2 2 193.10 5.65 2 2 354 39.0 4.63 HVO_1596 DUF790 family protein 5.60 1 2 2 3 1.723E7 200.68 5.60 2 3 500 53.9 4.65 HVO_1681 DNA N-glycosylase 5.59 1 2 2 4 1.434E7 2.36 5.59 2 2 216.72 5.59 2 2 304 34.2 4.63 HVO_1424 conserved hypothetical protein 5.57 1 2 2 6 1.385E7 4.51 5.57 2 3 150.38 5.57 2 3 359 40.9 4.60 18031720 keratin protein K6irs [Homo sapiens] 5.49 1 0 3 8 6.183E7 7.31 5.49 3 4 310.54 5.49 3 4 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 5.48 1 0 3 8 6.183E7 7.31 5.48 3 4 310.54 5.48 3 4 511 55.8 6.89 HVO_0745 "FtsZ family protein, type III" 5.28 1 2 2 2 1.402E7 1.98 5.28 2 2 360 37.1 4.51 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 5.24 1 3 3 6 1.004E7 2.20 5.24 3 3 259.06 5.24 3 3 573 62.9 4.45 31074633 keratin 6L [Homo sapiens] 5.23 1 0 3 10 1.416E8 9.84 5.23 3 5 740.06 5.23 3 5 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 5.23 1 0 3 10 1.416E8 9.84 5.23 3 5 740.06 5.23 3 5 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 5.23 1 0 3 10 1.416E8 9.84 5.23 3 5 740.06 5.23 3 5 535 57.7 7.20 HVO_B0285 transcription initiation factor TFB 5.23 1 0 2 3 8.656E7 305.08 5.23 2 3 344 38.4 5.14 HVO_2070 conserved hypothetical protein 5.15 1 2 2 4 4.676E6 5.50 5.15 2 2 369.13 5.15 2 2 544 58.1 4.50 HVO_0148 urease alpha subunit 5.11 1 2 2 6 8.882E6 6.01 5.11 2 3 295.66 5.11 2 3 568 60.3 4.54 HVO_1121 Fe-coproporphyrin synthase AhbC 4.98 1 2 2 4 1.355E7 0.00 4.98 2 2 119.21 4.98 2 2 402 44.4 4.67 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 4.90 1 4 5 9 2.674E7 1.94 2.21 2 3 339.79 4.90 5 6 858 93.9 4.69 HVO_2860 conserved hypothetical protein 4.80 1 2 2 2 1.004E7 1.86 4.80 2 2 562 58.9 4.49 HVO_C0057 Orc1-type DNA replication protein 4.78 1 2 2 4 2.106E7 4.84 4.78 2 2 313.76 4.78 2 2 418 46.3 5.02 4504911 keratin 13 isoform b [Homo sapiens] 4.76 1 0 2 5 5.123E7 4.23 4.76 2 3 194.16 4.76 2 2 420 45.8 4.88 HVO_A0257 Orc1-type DNA replication protein 4.71 1 2 2 9 1.118E7 7.61 4.71 2 5 541.50 4.71 2 4 425 48.0 4.94 66774007 "Keratin, type II cytoskeletal 1b" 4.69 1 0 3 8 8.207E7 1.72 4.69 3 4 319.65 4.69 3 4 576 61.7 5.85 HVO_2381 UPF0272 family protein 4.67 1 2 2 6 3.138E7 4.77 4.67 2 3 436.72 4.67 2 3 493 52.3 4.88 HVO_2035 TrmB family transcription regulator 4.57 1 2 2 4 1.183E7 0.00 4.57 2 2 86.21 4.57 2 2 372 40.9 5.07 HVO_B0309 aerobic-type carbon monoxide dehydrogenase large subunit 4.45 1 3 3 4 1.002E7 0.00 2.54 2 2 79.50 2.92 2 2 787 84.4 4.87 HVO_B0054 sirohydrochlorin cobaltochelatase 4.43 1 2 2 7 1.554E7 0.00 4.43 2 3 261.46 4.43 2 4 406 44.1 4.72 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 4.37 1 0 2 5 5.123E7 4.23 4.37 2 3 194.16 4.37 2 2 458 49.6 4.96 HVO_A0001 Orc1-type DNA replication protein 4.33 1 1 2 2 1.810E7 0.00 4.33 2 2 416 47.0 4.97 HVO_A0022 hypothetical protein 4.22 1 1 2 2 1.355E7 98.11 4.22 2 2 332 38.3 4.55 HVO_1650 polyphosphate kinase 4.21 1 3 3 6 7.337E6 2.16 4.21 3 3 275.54 4.21 3 3 832 93.6 4.65 HVO_2911 deoxyribodipyrimidine photolyase 4.13 1 2 2 2 8.846E6 172.16 4.13 2 2 484 54.5 4.79 HVO_B0076 N-methylhydantoinase (ATP-hydrolyzing) A 4.09 1 2 2 6 1.858E7 5.09 4.09 2 3 439.19 4.09 2 3 514 54.0 4.30 HVO_0065 DNA-directed DNA polymerase D large subunit 4.08 1 3 3 5 1.344E7 4.41 4.08 3 3 230.39 2.08 2 2 1202 133.9 4.60 HVO_0140 conserved hypothetical protein 4.06 1 2 2 2 1.167E7 35.39 4.06 2 2 689 77.5 4.77 HVO_2369 conserved hypothetical protein 4.01 1 2 2 6 1.064E7 0.00 4.01 2 3 160.69 4.01 2 3 424 47.3 5.06 HVO_0744 homolog to carboxylate-amine ligase 3.79 1 0 2 3 1.884E8 290.49 3.79 2 3 369 41.7 4.88 HVO_A0336 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 3.77 1 2 2 2 4.581E7 61.35 3.77 2 2 717 77.8 4.73 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 6 9.214E7 5.63 3.63 2 3 252.08 3.63 2 3 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.59 1 0 2 6 9.214E7 5.63 3.59 2 3 252.08 3.59 2 3 529 57.8 7.71 4504919 keratin 8 [Homo sapiens] 3.52 1 0 3 16 1.937E8 9.52 3.52 3 8 826.75 3.52 3 8 483 53.7 5.59 28173564 keratin 6 irs3 [Homo sapiens] 3.52 1 0 2 6 9.214E7 5.63 3.52 2 3 252.08 3.52 2 3 540 58.9 7.23 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 10 2.163E8 6.01 3.45 2 5 556.47 3.45 2 5 464 50.6 5.47 HVO_1113 "FtsZ family protein, type III" 3.34 1 0 2 4 6.079E8 430.63 3.34 2 4 389 40.8 4.89 HVO_2598 polyphosphate kinase 3.08 1 2 2 4 6.291E6 4.06 3.08 2 2 271.84 3.08 2 2 747 83.6 5.11 HVO_B0085 glycoside hydrolase family protein 2.97 1 1 2 3 1.384E8 163.77 2.97 2 3 538 57.8 4.42 HVO_A0180 SMC-like protein Sph1 2.70 1 2 2 4 5.874E7 2.23 2.70 2 2 194.52 2.70 2 2 593 66.4 4.58 109255249 keratin 4 [Homo sapiens] 2.69 1 0 2 4 1.259E8 4.13 2.69 2 2 252.14 2.69 2 2 594 63.9 8.25 HVO_2736 tRNA(Met) cytidine acetyltransferase 2.52 1 2 2 6 1.308E7 2.02 2.52 2 3 202.82 2.52 2 3 754 81.2 4.96 HVO_1940 DNA mismatch repair protein MutS 2.28 1 2 2 6 8.393E6 2.13 2.28 2 3 168.53 2.28 2 3 921 99.4 4.42