Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0359 translation elongation factor aEF-1 alpha subunit 77.43 1 18 22 690 2.543E10 692.61 64.61 19 318 53217.69 77.43 22 372 421 45.7 4.73 HVO_0356 translation elongation factor aEF-2 72.76 1 39 39 476 9.876E9 510.12 72.76 39 239 31886.67 71.80 38 237 727 80.4 4.73 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 72.57 1 18 18 236 5.316E9 250.24 72.57 18 117 17195.93 72.57 18 119 350 37.6 4.54 HVO_0880 conserved hypothetical protein 70.36 1 25 25 192 1.390E9 214.48 70.36 25 96 12493.92 70.36 25 96 307 36.3 4.74 HVO_0329 branched-chain amino acid aminotransferase 67.31 1 17 17 81 1.459E9 67.26 65.38 15 37 5525.84 67.31 17 44 312 35.0 4.58 HVO_2862 serine hydroxymethyltransferase 67.23 1 17 17 183 4.281E9 171.39 67.23 17 89 12429.41 67.23 17 94 415 44.3 4.53 HVO_1921 serine--tRNA ligase 64.35 1 24 24 117 1.297E9 118.43 56.30 23 58 7518.09 64.35 24 59 460 52.0 4.46 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 62.95 1 17 17 79 1.512E9 57.47 57.70 15 38 4667.44 62.95 17 41 305 33.8 4.74 HVO_0870 proline--tRNA ligase 61.89 1 19 19 86 7.170E8 64.29 59.43 18 42 5106.95 61.89 19 44 488 54.9 4.44 HVO_0055 CBS domain protein 61.62 1 12 12 77 1.266E9 74.05 61.62 12 38 5608.88 61.62 12 39 284 30.8 4.27 HVO_2969 threonine synthase 60.62 1 19 19 106 1.608E9 94.44 58.95 18 53 7037.65 60.62 19 53 419 44.4 4.49 HVO_0104 DNA repair and recombination protein RadA 60.35 1 13 13 83 1.099E9 70.48 55.10 12 41 5347.82 60.35 13 42 343 37.3 4.64 HVO_0433 F420H2:NADP oxidoreductase 59.01 1 9 9 31 6.392E8 31.95 54.50 8 15 1974.96 59.01 9 16 222 23.3 4.72 HVO_0348 DNA-directed RNA polymerase subunit B' 58.95 1 27 27 141 1.010E9 132.29 49.75 24 68 8998.56 58.95 27 73 609 67.7 4.92 HVO_1145 30S ribosomal protein S1e 58.18 1 11 11 52 9.948E8 46.76 58.18 11 25 3069.05 58.18 11 27 220 24.8 4.86 HVO_0118 50S ribosomal protein L20e 56.90 1 3 3 8 4.022E7 9.12 56.90 3 4 625.10 56.90 3 4 58 6.4 6.52 HVO_0025 thiosulfate sulfurtransferase 56.64 1 9 9 100 5.917E9 82.31 56.64 9 51 5271.87 56.64 9 49 286 32.1 4.28 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 56.42 1 15 15 81 1.929E9 60.83 55.45 14 39 4815.79 56.42 15 42 413 45.8 4.45 HVO_0400 conserved hypothetical protein 56.35 1 4 4 10 1.107E8 4.25 56.35 4 5 387.49 56.35 4 5 126 13.9 4.68 HVO_1507 acetolactate synthase small subunit 55.96 1 9 9 29 2.178E8 18.36 55.96 9 14 1544.36 55.96 9 15 218 23.7 4.94 HVO_0677 aspartate--tRNA ligase 55.30 1 18 18 207 4.807E9 193.48 53.69 17 102 12805.80 55.30 18 105 434 48.7 4.50 HVO_2413 translation elongation factor aEF-1 alpha subunit 55.24 1 12 16 113 5.930E9 80.73 50.95 15 54 6653.36 47.62 15 59 420 45.6 4.75 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 55.13 1 10 10 121 2.406E9 113.11 55.13 10 61 7097.05 55.13 10 60 312 34.5 4.98 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 54.86 1 13 13 104 4.102E9 95.26 54.86 13 51 6553.36 54.86 13 53 381 41.0 4.23 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 54.69 1 14 14 143 2.721E9 158.89 54.69 14 71 11466.24 54.69 14 72 384 41.4 4.41 HVO_1273 inosine-5'-monophosphate dehydrogenase 53.82 1 17 17 157 1.584E9 146.88 51.20 16 77 10576.69 49.00 16 80 498 53.3 4.55 HVO_0175 DNA polymerase sliding clamp 52.23 1 8 8 88 2.526E9 59.88 44.53 7 43 4860.91 52.23 8 45 247 26.7 4.39 HVO_0239 glutamine synthetase 52.19 1 17 17 100 2.075E9 85.86 48.03 16 50 5936.45 52.19 17 50 456 50.5 4.56 HVO_1132 adenylosuccinate synthase 52.14 1 22 22 171 2.740E9 99.61 48.98 21 83 8536.58 52.14 22 88 443 48.2 4.56 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 52.06 1 13 13 54 2.358E8 37.56 52.06 13 27 3030.49 47.35 12 27 340 38.8 4.58 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 51.60 1 14 14 62 4.864E8 53.01 51.60 14 30 4428.00 51.60 14 32 343 38.4 4.94 HVO_2646 dihydroxy-acid dehydratase 51.20 1 19 19 166 1.693E9 153.30 51.20 19 82 10134.30 46.92 18 84 584 61.8 4.42 HVO_B0059 cobalt-precorrin 5A hydrolase 50.92 1 12 12 56 7.211E8 60.52 50.92 12 29 3324.13 43.87 11 27 326 34.5 4.51 HVO_0161 ATP phosphoribosyltransferase 50.53 1 11 11 55 5.934E8 53.19 50.53 11 27 3702.00 50.53 11 28 281 30.4 4.60 HVO_1502 3-isopropylmalate dehydrogenase 50.31 1 12 12 82 1.599E9 70.51 39.81 10 38 5801.31 50.31 12 44 324 33.7 4.23 HVO_2015 conserved hypothetical protein 50.14 1 12 12 233 9.823E9 253.10 50.14 12 116 17418.22 50.14 12 117 345 37.7 4.25 HVO_0212 homolog to lactoylglutathione lyase 50.00 1 4 4 16 4.356E8 19.48 50.00 4 8 1313.92 50.00 4 8 124 13.5 4.13 HVO_0850 proteasome-activating nucleotidase 49.88 1 14 14 73 5.820E8 54.00 44.69 13 36 4259.02 49.88 14 37 405 45.6 4.60 HVO_0602 3-dehydroquinate dehydratase 49.80 1 9 9 26 1.829E8 20.15 49.80 9 13 1415.41 49.80 9 13 247 27.3 4.51 HVO_2588 isocitrate dehydrogenase (NADP) 49.64 1 18 18 176 3.127E9 158.63 46.54 17 85 11474.24 49.64 18 91 419 45.8 4.59 HVO_0778 thermosome subunit 3 49.62 1 17 19 99 9.195E8 112.67 49.62 19 50 7106.83 49.62 19 49 524 55.2 4.59 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 49.47 1 10 10 52 4.599E8 40.19 49.47 10 26 3102.72 49.47 10 26 281 30.6 4.59 HVO_1541 glycerol kinase 49.41 1 19 19 106 2.347E9 79.16 44.51 17 51 6272.45 49.41 19 55 510 56.7 4.50 HVO_2552 30S ribosomal protein S4e 48.99 1 8 8 53 5.274E9 53.32 46.96 7 24 4004.11 48.99 8 29 247 26.6 4.58 HVO_0999 DRTGG domain protein 48.94 1 13 13 68 8.076E8 59.22 48.94 13 34 4086.27 48.94 13 34 378 39.8 4.44 HVO_0317 A-type ATP synthase subunit B 48.29 1 15 15 105 2.403E9 123.49 48.29 15 52 8520.66 48.29 15 53 468 51.9 4.25 HVO_0347 DNA-directed RNA polymerase subunit B'' 47.98 1 25 25 137 8.022E8 95.25 47.98 25 69 7217.59 47.02 24 68 521 58.9 5.00 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 47.94 1 5 5 36 1.424E9 26.84 25.26 3 14 3073.86 47.94 5 22 194 20.7 4.12 HVO_2384 CBS domain protein 47.89 1 14 14 96 1.113E9 77.66 47.89 14 47 5854.85 47.89 14 49 380 42.5 5.01 HVO_2059 NAD-dependent epimerase/dehydratase 47.74 1 9 9 39 7.694E8 32.50 47.74 9 19 2393.88 47.74 9 20 310 34.1 4.40 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 47.61 1 11 11 46 6.322E8 38.26 45.35 10 22 3167.64 47.61 11 24 355 38.2 4.68 HVO_0859 FeS assembly ATPase SufC 47.51 1 10 10 111 1.739E9 89.42 47.51 10 55 6853.41 47.51 10 56 301 33.4 4.35 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 47.10 1 9 9 34 7.125E8 38.68 47.10 9 17 2675.80 47.10 9 17 259 28.0 4.50 HVO_2487 aspartate-semialdehyde dehydrogenase 46.80 1 9 9 67 1.758E9 52.11 46.80 9 34 2975.04 46.80 8 33 344 36.6 4.41 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 46.71 1 16 16 76 7.778E8 61.61 46.71 16 37 4242.22 46.71 16 39 471 51.0 4.48 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 46.49 1 19 19 75 4.636E8 69.67 46.49 19 37 4732.36 46.49 19 38 626 67.6 4.65 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 89 1.886E9 98.51 43.25 7 44 7689.42 46.37 8 45 289 29.8 4.27 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 46.34 1 9 9 96 2.362E9 108.00 46.34 9 48 7289.29 46.34 9 48 287 31.0 4.73 HVO_2783 30S ribosomal protein S4 46.29 1 9 9 47 7.403E8 38.39 46.29 9 23 3066.86 46.29 9 24 175 20.1 5.24 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 46.24 1 10 10 54 2.941E8 55.77 46.24 10 27 3544.77 46.24 10 27 266 27.8 4.84 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 46.21 1 13 13 67 3.459E8 68.28 36.73 11 31 3769.23 46.21 13 36 422 43.6 4.72 HVO_2013 "FtsZ family protein, type III" 46.19 1 10 10 50 7.876E8 53.17 46.19 10 25 3821.37 46.19 10 25 394 41.5 4.61 HVO_0480 phosphoglycerate kinase 46.13 1 16 16 75 1.388E9 66.60 46.13 16 38 5272.24 46.13 16 37 401 43.6 4.37 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 45.54 1 9 9 51 5.944E8 50.25 40.18 8 23 3617.92 45.54 9 28 336 36.8 4.12 HVO_0861 SufB domain protein 45.52 1 14 14 97 1.301E9 95.30 42.04 13 46 7221.35 45.52 14 51 402 44.7 4.23 HVO_1300 triosephosphate isomerase 45.33 1 6 6 32 1.265E9 37.69 45.33 6 17 2172.49 24.30 5 15 214 21.3 4.26 HVO_2968 phosphoglycerate dehydrogenase 45.33 1 17 17 145 4.084E9 173.65 44.19 16 72 10984.98 45.33 17 73 525 55.3 4.36 HVO_2700 AAA-type ATPase (CDC48 subfamily) 45.23 1 27 28 101 4.107E8 75.55 39.39 25 51 5406.80 45.23 28 50 754 82.8 4.75 HVO_1284 GTP cyclohydrolase III 45.21 1 8 8 31 2.671E8 28.81 36.40 7 15 2071.32 45.21 8 16 261 28.9 4.70 HVO_1577 conserved hypothetical protein 45.20 1 8 8 34 3.964E8 28.87 35.03 6 15 2195.55 45.20 8 19 177 19.4 4.74 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 45.12 1 9 9 37 8.161E8 31.40 40.40 8 17 2265.43 45.12 9 20 297 31.3 4.36 HVO_0388 homolog to ribonuclease R 45.10 1 15 15 64 3.109E8 65.59 32.12 13 30 4213.93 42.37 14 34 439 50.3 4.73 HVO_0829 peptidase S9 family protein 45.07 1 17 17 53 3.858E8 35.85 35.36 14 25 2720.04 45.07 17 28 608 67.4 4.54 HVO_2558 30S ribosomal protein S3 45.07 1 11 11 106 2.935E9 96.91 37.83 9 50 7587.73 45.07 11 56 304 33.4 4.06 HVO_0581 "cell division protein FtsZ, type II" 45.00 1 13 13 61 6.321E8 62.53 45.00 13 30 3801.88 45.00 13 31 400 42.5 4.75 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 45.00 1 10 10 53 1.346E9 52.15 45.00 10 27 3431.25 45.00 9 26 280 30.1 4.44 HVO_1189 aldehyde dehydrogenase 44.88 1 15 15 80 1.125E9 81.10 43.70 14 38 4981.90 44.88 15 42 508 56.1 4.59 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 44.86 1 13 13 76 6.198E8 59.19 44.86 13 37 4375.80 39.61 11 39 457 48.4 4.35 HVO_2549 30S ribosomal protein S8 44.62 1 5 5 22 5.642E8 17.27 44.62 5 11 1127.49 44.62 5 11 130 14.1 4.79 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 44.59 1 21 21 98 1.836E9 89.87 43.58 20 48 6323.87 44.59 21 50 592 66.6 4.61 HVO_1031 thioredoxin-disulfide reductase 44.44 1 10 10 43 3.488E8 44.45 39.77 9 20 2971.38 44.44 10 23 342 37.4 4.46 HVO_0449 prephenate dehydratase 44.40 1 9 9 44 5.753E8 36.86 41.42 8 21 2663.71 44.40 9 23 268 28.7 4.64 HVO_1649 methionine adenosyltransferase 44.28 1 11 11 46 6.347E8 48.96 34.58 10 23 3442.70 44.28 11 23 402 43.5 4.45 HVO_2621 phosphoenolpyruvate carboxylase 44.15 1 30 30 146 9.278E8 97.82 44.15 30 74 7912.14 44.15 30 72 897 102.3 4.64 HVO_0809 methionine--tRNA ligase 44.05 1 22 22 88 6.278E8 76.24 44.05 22 42 5125.83 44.05 22 46 740 81.9 4.37 HVO_2900 fumarate hydratase 43.92 1 13 13 95 1.660E9 112.06 40.72 11 45 6376.58 43.92 13 50 469 50.1 4.78 HVO_0792 3-dehydroquinate synthase type II 43.62 1 13 13 65 7.455E8 61.96 43.62 13 32 4616.37 43.62 13 33 392 43.1 4.44 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 43.47 1 36 36 195 1.353E9 174.85 39.69 33 95 12326.20 43.47 36 100 1033 114.3 4.45 HVO_A0205 CRISPR-associated endoribonuclease Cas6 43.38 1 10 10 50 2.630E8 39.27 43.38 10 25 2955.64 43.38 10 25 272 31.0 5.44 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 43.34 1 20 20 195 2.484E9 166.78 43.34 20 95 12498.91 43.34 20 100 586 64.0 4.49 HVO_2204 "FtsZ family protein, type III" 43.29 1 11 14 84 1.522E9 98.39 41.77 13 41 6664.57 43.29 14 43 395 42.0 4.68 HVO_A0207 CRISPR-associated protein Cas7 43.24 1 9 9 44 6.473E8 43.50 43.24 9 23 2681.35 43.24 9 21 340 38.2 4.54 HVO_1637 FKBP-type peptidylprolyl isomerase 43.14 1 10 10 56 2.682E9 61.19 34.64 9 26 3740.85 41.18 9 30 306 33.8 3.76 HVO_2191 formyltetrahydrofolate deformylase 43.12 1 11 11 42 7.175E8 42.16 40.98 10 20 2936.54 43.12 11 22 327 36.2 4.63 HVO_2225 AstE family protein 43.11 1 8 8 38 5.951E8 41.10 43.11 8 19 2380.19 35.19 7 19 341 36.9 4.53 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 42.93 1 6 6 25 4.853E8 30.87 37.50 5 11 2261.92 42.93 6 14 184 19.8 5.30 HVO_1172 NAD-dependent epimerase/dehydratase 42.86 1 11 11 38 1.105E9 27.55 40.32 10 18 2354.28 35.87 10 20 315 34.9 4.34 HVO_2188 phosphoribosylformylglycinamidine synthase 1 42.41 1 7 7 30 3.041E8 36.22 42.41 7 15 2188.79 39.29 6 15 224 23.9 4.36 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 42.29 1 14 14 70 7.408E8 69.22 40.38 13 33 4850.11 42.29 14 37 525 56.4 4.40 HVO_0869 glutamate synthase large subunit 42.03 1 48 48 210 9.090E8 187.10 41.43 46 100 13142.18 42.03 47 110 1511 163.8 4.70 HVO_2057 sugar nucleotidyltransferase 42.02 1 12 12 73 1.221E9 70.52 42.02 12 35 4641.26 42.02 12 38 357 37.8 4.44 HVO_2774 enolase 41.85 1 10 10 58 1.283E9 61.96 41.85 10 29 4102.23 41.85 10 29 399 42.0 4.37 HVO_0860 SufB domain protein 41.81 1 16 16 104 1.818E9 93.10 38.66 14 49 6213.10 41.81 16 55 476 53.2 4.69 HVO_0789 tryptophan synthase alpha subunit 41.52 1 7 7 38 2.458E8 24.50 41.52 7 19 1676.14 41.52 7 19 277 29.6 4.21 HVO_0455 thermosome subunit 2 41.47 1 18 19 111 1.146E9 100.92 41.47 19 54 7492.28 41.47 19 57 557 59.3 4.37 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 41.37 1 12 12 49 1.460E8 35.70 39.58 11 24 2592.98 41.37 12 25 336 38.0 4.61 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 41.31 1 8 8 28 2.635E8 24.29 41.31 8 15 1345.46 41.31 8 13 305 32.7 4.56 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 41.26 1 8 8 42 4.338E8 28.11 41.26 8 21 2221.27 41.26 8 21 286 31.2 4.54 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 41.21 1 10 10 37 2.710E8 29.97 39.39 9 18 2247.75 41.21 10 19 330 36.3 4.35 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 41.20 1 18 18 247 5.354E9 257.40 39.94 17 121 17538.98 41.20 18 126 631 68.4 4.49 HVO_1454 aspartate carbamoyltransferase catalytic subunit 41.12 1 8 8 27 1.304E8 20.96 41.12 8 14 1664.05 32.24 7 13 304 33.7 4.92 HVO_2724 beta-lactamase domain protein 41.11 1 13 13 95 1.107E9 78.71 37.56 12 47 5418.56 41.11 13 48 450 50.1 5.40 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 40.93 1 10 10 125 9.510E8 73.46 37.07 9 59 7310.29 40.93 10 66 259 29.9 4.36 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 40.90 1 12 12 53 6.412E8 56.64 39.33 11 25 3803.40 38.88 11 28 445 47.8 4.86 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 40.90 1 19 19 64 4.097E8 63.20 40.23 18 31 4010.77 40.90 19 33 599 65.3 4.51 HVO_0046 putative glutamate--argW ligase 40.89 1 9 9 55 5.493E8 51.90 37.80 8 27 3694.10 40.89 9 28 291 31.9 4.87 HVO_0024 thiosulfate sulfurtransferase 40.70 1 8 8 35 4.461E8 30.23 30.62 5 15 2411.29 40.70 8 20 258 28.4 4.30 HVO_0203 replication factor C small subunit 40.37 1 10 10 43 1.905E8 37.62 40.37 10 22 2609.82 33.64 9 21 327 36.2 4.51 HVO_1955 aconitate hydratase 40.06 1 21 21 174 3.713E9 169.26 38.38 19 84 12016.56 40.06 21 90 654 70.4 4.45 HVO_0549 2-keto-3-deoxygluconate kinase 40.00 1 12 12 40 2.799E8 33.39 36.25 11 20 2596.74 39.69 11 20 320 34.1 4.34 HVO_1164 HD family hydrolase 40.00 1 11 11 37 3.040E8 24.76 40.00 11 19 1836.18 35.19 10 18 270 29.8 4.87 HVO_1504 3-isopropylmalate dehydratase large subunit 39.96 1 17 17 102 1.605E9 84.06 39.96 17 51 6786.17 39.96 17 51 473 51.6 4.55 HVO_1854 histidine--tRNA ligase 39.91 1 14 14 66 5.871E8 51.08 35.96 12 30 4595.22 39.91 14 36 431 47.1 4.37 HVO_2981 uracil phosphoribosyltransferase 39.82 1 7 7 28 8.384E8 20.37 37.61 6 12 2164.30 39.82 7 16 226 24.5 4.49 HVO_1684 threonine--tRNA ligase 39.81 1 22 22 112 1.386E9 107.83 39.81 22 54 7677.59 39.81 22 58 643 73.4 4.45 HVO_1545 dihydroxyacetone kinase subunit DhaL 39.66 1 7 7 35 6.162E8 17.18 39.66 7 17 1430.75 39.66 7 18 232 24.8 4.48 HVO_0316 A-type ATP synthase subunit A 39.59 1 16 16 83 1.106E9 89.86 39.59 16 41 5818.38 39.59 16 42 586 64.5 4.25 HVO_1344 SBDS family protein 39.50 1 6 6 20 9.579E7 16.05 39.50 6 10 970.49 39.50 6 10 238 26.5 4.51 HVO_A0206 CRISPR-associated protein Cas8b 39.47 1 22 22 77 4.225E8 56.82 38.77 20 37 4144.33 36.68 21 40 717 79.3 4.60 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 39.10 1 17 17 86 1.109E9 85.01 37.82 16 42 6016.25 39.10 17 44 624 67.6 4.27 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 38.51 1 13 13 44 3.651E8 35.80 36.78 11 21 2307.59 38.51 13 23 348 38.2 4.32 HVO_0806 pyruvate kinase 38.46 1 16 16 115 1.812E9 98.91 38.46 16 56 7009.48 38.46 16 59 585 62.0 4.54 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 38.31 1 15 15 85 7.808E8 58.24 38.31 15 42 4717.42 38.31 15 43 496 55.0 4.53 HVO_0879 DUF371 family protein 38.30 1 4 5 11 4.730E7 3.99 34.75 4 5 412.89 38.30 5 6 141 15.3 4.65 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 38.19 1 13 13 53 5.125E8 48.67 34.18 12 26 3172.80 38.19 13 27 474 53.4 4.59 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 66 5.700E8 60.76 35.50 8 30 4519.58 38.05 9 36 431 46.1 4.48 HVO_0717 "cell division protein FtsZ, type I" 37.99 1 12 13 86 2.978E9 78.00 37.99 13 42 6012.39 37.99 13 44 379 39.8 4.40 HVO_1332 conserved hypothetical protein 37.98 1 5 5 14 1.449E8 12.44 29.46 4 6 913.68 37.98 5 8 129 14.9 4.16 HVO_1590 DnaK-type molecular chaperone Hsp70 37.92 1 21 21 131 2.643E9 109.35 36.96 19 63 8149.22 37.92 21 68 625 67.2 4.18 HVO_0729 inorganic pyrophosphatase 37.85 1 6 6 33 8.511E8 42.07 37.85 6 17 2437.89 37.85 6 16 177 20.4 4.16 HVO_1973 conserved hypothetical protein 37.72 1 3 3 9 1.118E8 7.94 37.72 3 4 414.40 37.72 3 5 167 18.1 4.36 HVO_0314 A-type ATP synthase subunit C 37.64 1 10 10 35 2.707E8 18.92 33.62 9 16 1950.87 37.64 10 19 348 38.7 4.50 HVO_1212 KaiC-type circadian regulator CirA 37.40 1 8 8 44 9.216E8 49.25 37.40 8 22 3447.50 37.40 8 22 246 27.5 4.45 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 37.37 1 5 5 23 7.014E8 20.86 37.37 5 12 1546.22 26.32 4 11 190 20.6 4.30 HVO_0133 thermosome subunit 1 37.14 1 14 16 116 2.137E9 107.47 37.14 16 57 7975.47 37.14 16 59 560 58.9 4.25 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.05 1 11 11 60 9.417E8 41.33 37.05 11 30 3108.75 37.05 11 30 332 34.8 4.22 HVO_2889 RecJ domain protein 37.04 1 19 19 120 1.840E9 98.93 37.04 19 60 6703.77 37.04 19 60 729 79.1 4.37 HVO_1091 proteasome alpha subunit 36.90 1 8 9 42 6.754E8 44.67 36.90 9 21 2988.50 36.90 9 21 252 27.6 4.56 HVO_1306 chorismate synthase 36.88 1 11 11 62 3.824E8 53.27 36.88 11 30 2998.78 36.88 11 32 385 41.9 4.83 HVO_1967 glucose-6-phosphate isomerase 36.74 1 10 10 51 3.058E8 45.91 36.74 10 25 3346.72 36.74 10 26 430 45.6 4.40 HVO_2435 peptidase M24 family protein 36.68 1 8 8 38 2.724E8 30.15 36.68 8 19 2216.43 36.68 8 19 368 40.0 4.53 HVO_0041 ornithine carbamoyltransferase 36.45 1 7 7 44 3.433E8 37.03 36.45 7 22 2303.78 36.45 7 22 299 32.7 4.37 HVO_2519 conserved hypothetical protein 36.13 1 10 10 42 5.336E8 48.82 31.41 9 19 3606.44 36.13 10 23 382 40.7 4.35 HVO_0353 30S ribosomal protein S12 35.92 1 7 7 34 5.172E8 32.71 35.92 7 17 2338.19 35.92 7 17 142 15.5 9.91 HVO_1690 DHH family phosphoesterase 35.88 1 10 10 38 1.089E8 26.79 35.88 10 18 2009.18 35.88 10 20 485 52.1 4.48 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 35.84 1 8 8 52 1.146E9 47.30 35.84 8 27 3460.99 35.84 8 25 226 25.5 4.25 HVO_1370 gamma-glutamyl phosphate reductase 35.59 1 13 13 61 7.721E8 45.36 35.59 13 31 3264.74 35.59 13 30 444 48.1 4.34 HVO_0206 alanine--tRNA ligase 35.47 1 24 24 93 3.017E8 76.70 33.84 22 47 5590.79 31.78 23 46 922 102.4 4.54 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 35.44 1 10 10 47 2.807E8 45.10 27.47 9 23 3156.16 35.44 10 24 364 39.3 4.35 HVO_B0118 SMC-like protein Sph2 35.40 1 21 21 103 9.927E8 72.76 35.40 21 51 5592.69 35.40 21 52 644 73.8 4.41 HVO_2624 CTP synthase 35.34 1 14 14 67 9.434E8 46.75 33.33 13 31 4441.80 35.34 14 36 549 60.8 4.70 HVO_0393 UvrABC system protein A 35.30 1 28 28 88 2.049E8 64.03 31.74 26 41 4400.45 34.79 27 47 983 108.6 4.82 HVO_1082 homolog to orotate phosphoribosyltransferase 35.24 1 7 7 22 2.739E8 12.97 35.24 7 11 946.86 35.24 7 11 210 22.3 4.42 HVO_1076 sugar nucleotidyltransferase 35.09 1 7 7 42 7.801E8 44.06 35.09 7 21 3093.52 35.09 7 21 322 35.8 4.20 HVO_0424 ABC-type transport system ATP-binding protein 34.93 1 15 15 63 3.004E8 49.84 31.46 13 30 3332.98 34.93 15 33 604 67.2 4.49 HVO_0415 repair helicase 34.90 1 18 18 69 4.520E8 68.06 34.90 18 33 4694.83 34.90 18 36 616 69.6 4.70 HVO_2675 histidinol dehydrogenase 34.81 1 10 10 42 3.978E8 39.92 34.81 9 19 3120.03 34.81 10 23 428 45.4 4.50 HVO_0743 probable phosphodiesterase 34.74 1 18 18 97 1.177E9 66.88 34.74 17 46 5837.66 34.74 18 51 449 50.5 4.56 HVO_0167 adenosylhomocysteinase 34.58 1 12 12 42 6.235E8 39.40 30.37 10 18 3496.96 32.94 11 24 428 46.6 4.39 HVO_0324 arginine--tRNA ligase 34.58 1 17 17 91 8.887E8 88.96 34.58 16 44 5801.31 34.58 17 47 587 65.0 4.35 HVO_2708 YfiH family protein 34.47 1 7 7 20 3.207E8 23.64 34.47 7 10 1796.87 30.12 6 10 322 35.4 4.35 HVO_B0061 precorrin-2 C20-methyltransferase 34.47 1 6 6 47 2.889E8 33.79 34.47 6 23 2501.38 34.47 6 24 235 25.3 4.63 HVO_2813 RimK family protein 34.44 1 12 12 64 5.943E8 62.57 32.67 11 31 4269.53 34.44 12 33 453 49.0 4.73 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 34.42 1 11 11 37 2.183E8 29.13 34.42 11 17 1908.15 34.42 11 20 430 45.1 4.50 HVO_2417 conserved hypothetical protein 34.36 1 5 5 25 2.739E8 27.18 34.36 5 12 1674.13 34.36 5 13 195 21.6 3.65 HVO_0417 metal-dependent carboxypeptidase 34.06 1 13 13 47 3.303E8 42.79 34.06 13 23 2681.10 34.06 13 24 502 57.3 4.42 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 34.04 1 5 5 26 2.106E8 14.03 33.51 4 13 1335.19 34.04 5 13 188 20.5 4.60 HVO_2454 anthranilate synthase component I 33.97 1 14 14 35 2.923E8 24.06 29.01 12 16 1802.73 33.97 14 19 524 55.9 4.56 HVO_2419 hydroxymethylglutaryl-CoA synthase 33.93 1 11 11 47 5.777E8 28.47 28.31 10 22 2191.23 33.93 11 25 445 50.1 4.64 HVO_1506 ketol-acid reductoisomerase 33.91 1 7 7 39 4.108E8 39.98 33.91 7 18 2946.63 33.91 7 21 348 37.9 4.34 HVO_0350 DNA-directed RNA polymerase subunit A'' 33.89 1 11 11 42 1.213E9 34.06 28.40 10 20 2385.45 32.70 10 22 419 46.1 4.35 HVO_0233 ribose-phosphate pyrophosphokinase 33.57 1 6 6 25 9.817E7 24.03 33.57 6 12 1296.63 33.57 6 13 283 29.6 4.40 HVO_0313 A-type ATP synthase subunit E 33.51 1 4 4 14 8.651E7 14.21 26.29 3 6 1014.59 33.51 4 8 194 22.0 4.31 HVO_1660 DisA-N domain protein 33.46 1 7 7 22 1.791E8 23.38 33.46 7 11 1431.49 33.46 7 11 269 28.9 4.73 HVO_A0496 UspA domain protein 33.45 1 8 8 36 4.360E8 38.15 33.45 8 18 2488.53 33.45 8 18 290 31.4 4.60 40354192 keratin 10 [Homo sapiens] 33.39 1 0 18 67 3.591E8 55.46 32.19 17 32 4057.37 33.39 18 35 584 58.8 5.16 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 33.27 1 10 10 46 6.412E8 38.40 33.27 10 21 2754.91 33.27 10 25 526 57.2 4.31 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 33.17 1 5 5 23 7.762E7 14.82 33.17 5 12 1068.05 33.17 5 11 202 22.2 5.11 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 33.11 1 11 11 47 5.052E8 40.23 31.10 10 23 3130.78 33.11 11 24 447 48.5 4.56 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 32.91 1 14 14 51 2.795E8 65.33 31.62 13 25 3764.86 32.91 14 26 623 62.1 5.30 HVO_A0636 YbaK domain protein 32.91 1 3 3 12 4.709E7 11.96 32.91 3 6 547.70 32.91 3 6 158 16.7 4.54 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 32.89 1 11 11 46 4.748E8 45.51 32.89 11 22 2993.89 32.89 11 24 453 47.5 4.63 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 32.88 1 0 18 67 3.591E8 55.46 31.70 17 32 4057.37 32.88 18 35 593 59.5 5.21 HVO_1134 conserved hypothetical protein 32.63 1 17 17 76 4.991E8 80.56 32.63 17 39 4743.75 32.63 17 37 757 80.6 4.35 HVO_2726 glutamate--tRNA ligase 32.48 1 15 15 67 3.465E8 45.42 27.86 14 32 3611.77 32.48 15 35 585 65.2 4.58 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 32.44 1 16 16 65 6.509E8 52.36 25.92 14 31 3989.68 32.44 16 34 706 73.3 4.39 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 32.43 1 8 9 36 1.071E8 32.36 32.43 9 18 1826.64 32.43 9 18 333 36.7 4.56 HVO_2879 ornithine cyclodeaminase 32.23 1 7 7 32 1.171E9 21.29 24.70 6 13 2265.12 32.23 7 19 332 34.6 4.45 HVO_0874 beta-lactamase domain protein 32.19 1 17 17 76 1.142E9 70.96 32.19 17 38 5337.72 32.19 17 38 640 71.9 5.14 HVO_2619 ubiquitin-like modifier protein SAMP1 32.18 1 2 2 2 7.503E7 108.81 32.18 2 2 87 8.9 4.26 HVO_0292 replication protein A 32.15 1 8 8 28 2.641E8 18.44 32.15 8 14 1761.63 32.15 8 14 311 34.6 4.31 HVO_0980 NADH dehydrogenase-like complex subunit CD 32.14 1 12 16 75 4.859E8 58.66 32.14 16 37 4085.03 32.14 16 38 557 63.4 4.53 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 31.96 1 3 3 10 1.911E8 6.66 31.96 3 5 564.90 31.96 3 5 97 10.8 4.53 HVO_0109 cysteine desulfurase 31.92 1 10 10 50 2.998E8 43.58 31.92 10 25 3190.13 30.75 9 25 426 46.8 4.56 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 31.74 1 14 14 68 2.822E8 67.49 31.74 14 34 4408.99 31.74 14 34 586 63.4 4.70 HVO_1654 cysteine synthase 31.70 1 7 7 30 2.054E8 17.23 31.70 7 15 1570.40 31.70 7 15 306 32.3 4.32 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 31.70 1 7 7 25 1.721E8 18.27 31.70 7 12 1399.66 31.70 7 13 265 28.7 4.87 HVO_3007 malate dehydrogenase 31.58 1 9 9 64 2.550E9 63.11 31.58 9 31 4227.31 31.58 9 33 304 32.6 4.40 HVO_1371 glutamate 5-kinase 31.56 1 7 7 32 5.273E8 35.27 31.56 7 16 2350.49 31.56 7 16 301 32.0 4.25 HVO_2643 NADPH:quinone reductase 31.50 1 8 8 35 2.511E8 35.28 31.50 8 17 2179.79 31.50 8 18 346 37.2 4.55 HVO_1932 2-D-hydroxyacid dehydrogenase 31.49 1 8 8 28 1.650E8 26.62 31.49 8 14 1581.04 31.49 8 14 308 33.0 4.60 HVO_0431 HAD superfamily hydrolase 31.34 1 6 6 19 8.807E7 12.42 31.34 6 10 899.07 19.72 5 9 284 30.4 4.26 HVO_0100 NMD3 family protein 31.20 1 8 8 25 9.438E7 15.63 29.33 7 12 1292.83 28.00 7 13 375 41.6 4.46 HVO_1198 UspA domain protein 31.03 1 4 4 14 2.141E8 16.99 31.03 4 7 817.63 31.03 4 7 145 15.6 4.75 HVO_B0018 ParA domain protein 31.01 1 5 5 22 1.090E8 20.30 31.01 5 11 1241.60 31.01 5 11 287 31.7 4.74 HVO_0997 peptidase M24 family protein 30.98 1 7 7 26 1.588E8 21.19 30.98 7 11 1547.83 30.98 7 15 368 39.9 4.49 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 42 6.263E8 35.11 30.84 8 21 2664.02 30.84 8 21 415 44.4 4.41 HVO_1018 RecJ domain protein 30.65 1 18 18 82 5.527E8 66.50 30.65 18 39 5139.73 30.65 18 43 633 69.8 4.58 HVO_B0375 Spo0M family protein 30.61 1 5 5 16 2.277E8 19.49 30.61 5 8 1134.39 30.61 5 8 245 27.2 4.35 HVO_1097 diaminopimelate epimerase 30.56 1 6 6 21 9.694E7 19.79 27.08 5 10 1238.13 30.56 6 11 288 29.9 4.48 HVO_2781 DNA-directed RNA polymerase subunit D 30.50 1 6 6 39 9.173E8 30.93 26.25 5 18 2769.16 30.50 6 21 259 28.1 4.32 HVO_1295 histidinol-phosphate aminotransferase 30.47 1 9 9 26 1.261E8 17.81 30.47 9 12 1297.19 30.47 9 14 361 39.4 4.51 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 30.47 1 3 3 10 8.537E7 12.43 30.47 3 5 752.78 30.47 3 5 128 13.0 4.31 HVO_0008 aspartate kinase 30.36 1 10 10 66 1.938E9 60.45 28.32 9 33 3917.14 30.36 10 33 392 41.7 4.46 HVO_0661 dCTP deaminase (dUMP-forming) 30.26 1 4 4 15 9.441E7 5.87 30.26 4 7 464.68 30.26 4 8 195 21.2 4.59 HVO_1338 replication protein A 30.21 1 9 9 33 2.371E8 22.58 30.21 9 16 2056.81 30.21 9 17 427 46.0 4.36 HVO_0138 tyrosine--tRNA ligase 30.18 1 5 5 14 2.833E8 6.16 19.21 4 6 708.03 30.18 5 8 328 36.1 4.34 HVO_2425 GNAT family acetyltransferase 30.09 1 5 5 22 4.793E8 20.06 30.09 5 11 1490.64 30.09 5 11 216 24.4 4.54 HVO_2773 30S ribosomal protein S2 30.00 1 5 5 35 2.264E9 33.57 30.00 5 19 2381.06 30.00 5 16 260 28.3 4.16 HVO_0358 homoserine dehydrogenase 29.97 1 5 6 26 4.722E8 33.47 29.97 6 13 2139.98 29.97 6 13 317 32.4 4.44 17318569 keratin 1 [Homo sapiens] 29.81 1 1 21 100 6.732E8 96.96 29.81 19 48 6541.57 29.81 21 52 644 66.0 8.12 HVO_2040 NAD-dependent epimerase/dehydratase 29.74 1 4 8 56 8.745E8 45.99 29.74 8 27 3486.95 29.74 7 29 306 33.8 4.51 HVO_1133 conserved hypothetical protein 29.70 1 2 2 6 2.320E8 7.36 29.70 2 3 432.15 29.70 2 3 101 11.7 4.58 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 29.63 1 6 6 19 1.340E8 13.88 26.30 5 9 1011.52 29.63 6 10 270 29.1 4.35 HVO_0349 DNA-directed RNA polymerase subunit A' 29.51 1 23 23 101 3.577E8 81.40 29.51 23 50 6395.43 29.51 23 51 976 108.8 4.81 HVO_1901 translation initiation factor aIF-2 gamma subunit 29.44 1 10 10 51 1.164E9 32.65 29.44 10 25 2574.15 29.44 10 26 411 43.9 4.36 HVO_1572 DNA gyrase subunit B 29.42 1 16 16 68 2.112E8 51.43 24.73 14 34 3746.44 28.48 15 34 639 71.2 4.83 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 29.39 1 9 9 27 2.539E8 21.48 29.39 9 14 1593.60 23.68 8 13 473 50.8 4.58 HVO_1084 adenylosuccinate lyase 29.37 1 11 11 45 2.109E8 41.03 29.37 11 22 2338.42 29.37 11 23 463 50.8 4.70 HVO_0122 phosphoglycerate dehydrogenase 29.32 1 7 7 28 1.571E8 23.01 22.22 6 13 1571.53 29.32 7 15 324 35.3 5.35 HVO_2481 HD family hydrolase 29.23 1 7 7 14 7.221E7 5.94 13.08 4 5 497.86 29.23 7 9 390 42.7 6.14 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 29.19 1 11 11 79 1.052E9 53.48 25.95 10 39 4450.64 29.19 11 40 370 41.9 4.48 HVO_1025 acetyl-CoA C-acyltransferase 28.98 1 6 6 23 1.542E8 21.55 28.98 6 11 1378.79 28.98 6 12 383 40.7 4.56 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 28.97 1 6 6 20 4.442E8 23.36 28.97 6 10 1607.77 28.97 6 10 252 26.0 4.39 HVO_B0066 Lrp/AsnC family transcription regulator 28.66 1 3 3 8 2.919E7 4.87 28.66 3 4 335.67 28.66 3 4 164 18.5 4.41 HVO_3014 origin-associated GTP-binding protein OapA 28.64 1 5 5 13 5.766E7 1.75 23.47 4 6 420.70 28.64 5 7 213 24.0 5.01 HVO_B0052 PQQ repeat protein 28.64 1 11 11 30 1.788E8 24.51 28.64 11 15 2057.41 28.64 11 15 412 44.1 5.48 HVO_0243 threonine aldolase 28.45 1 7 7 21 1.099E8 17.89 28.45 7 11 1114.34 23.17 6 10 341 35.6 4.55 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 28.45 1 7 7 30 5.611E8 25.11 25.41 6 13 2019.00 28.45 7 17 362 39.6 4.82 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 28.42 1 0 20 96 6.732E8 92.68 28.42 18 46 6269.20 28.42 20 50 644 66.0 8.12 HVO_0519 replication protein A 28.36 1 10 11 46 4.362E8 44.62 26.09 10 22 3358.29 28.36 11 24 483 51.0 4.13 HVO_2861 conserved hypothetical protein 28.36 1 8 8 39 4.187E8 28.09 28.36 8 19 2072.27 28.36 8 20 275 29.1 4.27 HVO_2912 ThiJ/PfpI domain protein 28.36 1 3 3 13 5.672E7 11.06 28.36 3 6 669.04 28.36 3 7 201 20.9 4.36 HVO_2544 30S ribosomal protein S5 28.04 1 5 5 28 1.537E9 31.53 28.04 5 14 2052.70 28.04 5 14 214 23.3 9.29 HVO_1291 fumarylacetoacetase family protein 27.98 1 5 5 25 8.586E8 20.27 25.51 4 12 1359.53 27.98 5 13 243 26.3 4.55 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 27.97 1 8 8 34 1.819E8 31.74 27.97 8 17 1947.81 27.97 8 17 454 48.5 4.46 HVO_2496 adenylate kinase 27.88 1 6 6 28 1.287E9 36.11 27.88 6 14 2415.25 27.88 6 14 208 23.1 4.25 HVO_B0049 precorrin-8 methylmutase 27.88 1 4 4 15 7.166E7 0.00 27.88 4 7 471.61 27.88 4 8 226 23.8 5.00 HVO_1571 DNA topoisomerase VI subunit B 27.82 1 15 15 61 2.314E8 42.82 25.44 14 30 3011.20 27.82 15 31 798 87.4 4.73 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 27.73 1 10 10 38 2.357E8 41.10 27.73 10 19 2452.19 27.73 10 19 512 53.8 4.78 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 27.73 1 8 8 27 3.134E8 11.99 27.73 8 13 1150.32 25.21 7 14 357 39.8 4.41 HVO_2707 GFO family oxidoreductase 27.42 1 8 8 29 3.678E8 32.26 27.42 8 15 1798.45 22.04 7 14 372 41.0 4.55 HVO_0573 endonuclease IV 27.15 1 5 5 27 4.602E8 24.34 27.15 5 13 1707.27 27.15 5 14 291 31.4 4.44 HVO_1496 phosphotransferase system component I 27.08 1 11 11 48 4.608E8 56.29 27.08 11 24 3469.78 27.08 11 24 565 60.3 4.21 HVO_0989 conserved hypothetical protein 26.98 1 3 3 6 7.001E7 524.17 26.98 3 6 126 14.4 4.81 HVO_1824 conserved hypothetical protein 26.81 1 8 8 27 1.632E8 28.52 25.87 7 13 1859.20 26.81 8 14 429 47.4 4.20 HVO_1527 glucose-1-phosphate uridylyltransferase 26.75 1 6 6 31 3.226E8 26.33 26.75 6 15 1794.83 26.75 6 16 243 27.5 4.70 HVO_2740 nucleoside-diphosphate kinase 26.62 1 3 3 10 7.377E7 7.87 26.62 3 5 678.88 26.62 3 5 154 17.5 4.50 HVO_0354 30S ribosomal protein S7 26.47 1 5 5 19 2.668E8 17.83 26.47 5 9 1127.19 26.47 5 10 204 22.6 5.14 HVO_1481 UspA domain protein 26.38 1 3 3 8 1.889E8 7.00 26.38 3 4 589.15 26.38 3 4 163 17.7 4.40 HVO_2947 phenylalanine--tRNA ligase beta subunit 26.32 1 11 11 46 2.816E8 35.30 24.39 10 22 2576.66 26.32 11 24 570 63.3 4.46 HVO_1491 HAD superfamily hydrolase 26.23 1 10 10 29 9.608E7 11.69 26.23 10 14 1136.13 23.28 9 15 408 44.4 4.60 HVO_B0058 precorrin-3B C17-methyltransferase 26.19 1 5 5 14 1.355E8 11.03 26.19 5 7 881.81 26.19 5 7 294 31.8 4.40 HVO_2336 pyridoxal biosynthesis lyase PdxS 26.16 1 8 8 25 1.069E8 21.31 22.52 6 11 1600.36 26.16 8 14 302 32.5 4.81 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 20 2.481E8 18.23 26.15 3 10 1205.54 26.15 3 10 130 13.4 8.56 HVO_1568 alpha/beta hydrolase fold protein 25.99 1 5 5 19 7.713E7 16.16 25.99 5 11 941.89 22.74 4 8 277 29.4 4.94 HVO_1573 DNA gyrase subunit A 25.99 1 21 21 77 4.435E8 60.18 25.99 21 39 4469.88 24.94 20 38 862 94.8 4.56 HVO_2547 50S ribosomal protein L32e 25.96 1 4 4 12 8.950E7 9.30 18.72 3 5 1125.93 25.96 4 7 235 25.8 4.75 HVO_1327 AAA-type ATPase (CDC48 subfamily) 25.95 1 14 15 51 2.198E8 29.21 24.18 14 24 2289.84 25.95 15 27 736 78.1 4.88 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 25.84 1 4 5 22 1.388E8 14.77 25.84 5 11 1261.74 25.84 5 11 267 29.1 4.63 HVO_1488 D-gluconate dehydratase 25.73 1 7 9 63 1.165E9 53.60 25.73 9 31 4289.16 25.73 9 32 412 45.8 4.60 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 25.60 1 11 11 47 4.473E8 28.75 25.60 11 24 2443.08 25.60 11 23 461 50.7 4.73 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 25.56 1 6 6 41 3.886E8 30.74 25.56 6 20 2139.95 25.56 6 21 360 39.6 4.39 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 25.56 1 6 6 18 1.177E8 10.16 25.56 6 9 1050.63 25.56 6 9 266 29.7 4.32 HVO_2706 translation initiation factor aIF-2B delta subunit 25.53 1 6 6 22 2.918E8 17.90 25.53 6 11 1167.78 25.53 6 11 282 30.7 4.42 HVO_1576 NAD-dependent epimerase/dehydratase 25.49 1 3 7 33 6.313E8 31.15 25.49 7 16 2030.80 25.49 6 17 306 33.9 4.51 HVO_0467 PhoU/TrkA-C domain protein 25.37 1 8 8 26 1.379E8 18.93 25.37 8 13 1387.60 25.37 8 13 402 43.3 4.49 HVO_A0350 conserved hypothetical protein 25.35 1 5 5 12 9.841E7 5.36 20.19 4 6 605.62 25.35 5 6 213 23.8 9.64 HVO_1412 diphosphomevalonate decarboxylase 25.31 1 8 8 38 1.007E9 23.09 25.31 8 19 2116.65 25.31 8 19 324 35.4 4.78 HVO_B0057 precorrin-3B C17-methyltransferase 25.29 1 5 5 30 1.036E9 28.97 25.29 5 14 1834.58 25.29 5 16 344 36.3 4.31 HVO_0658 tRNA pseudouridine(13) synthase TruD 25.27 1 7 7 23 9.088E7 16.51 25.27 7 11 1097.80 19.87 6 12 463 50.6 4.70 HVO_1778 catalase-peroxidase 25.21 1 11 11 54 5.894E8 49.51 25.21 11 27 3794.34 25.21 11 27 718 80.0 4.31 7428712 "keratin 1, type II, cytoskeletal - human" 25.19 1 0 18 90 6.732E8 90.94 25.19 16 43 5999.22 25.19 18 47 643 65.5 6.35 HVO_1148 30S ribosomal protein S15 25.16 1 4 4 14 3.631E7 3.55 25.16 4 7 555.76 25.16 4 7 155 17.5 4.91 >sp|TRYP_PIG| 25.11 1 4 4 77 2.048E10 89.44 25.11 4 39 6370.82 25.11 4 38 231 24.4 7.18 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 25.00 1 12 12 48 2.641E8 42.82 22.83 11 23 3452.80 25.00 12 25 600 65.3 4.68 HVO_2300 translation initiation factor aIF-5A 25.00 1 2 2 13 8.471E8 11.67 25.00 2 6 1043.76 25.00 2 7 124 14.2 5.22 HVO_0401 UspA domain protein 25.00 1 2 2 3 2.726E8 481.08 25.00 2 3 152 16.4 4.79 HVO_2721 amidophosphoribosyltransferase 24.95 1 8 8 30 3.876E8 13.47 24.95 8 15 1253.48 24.95 8 15 493 53.4 4.78 HVO_0049 argininosuccinate synthase 24.94 1 9 9 35 1.517E9 29.63 22.47 8 17 2232.48 24.94 9 18 405 44.5 4.34 HVO_0916 diphthine synthase 24.91 1 5 5 12 1.480E8 9.82 18.59 4 5 653.88 24.91 5 7 269 29.1 4.54 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 24.87 1 4 4 19 1.872E8 10.88 17.99 3 9 974.48 24.87 4 10 189 21.7 4.46 HVO_0889 FAD-dependent oxidoreductase 24.77 1 3 3 7 1.103E8 7.75 24.77 3 4 462.75 12.62 2 3 214 21.8 3.89 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 24.77 1 7 7 20 8.746E7 16.96 21.10 6 9 1230.16 24.77 7 11 327 36.0 4.73 HVO_A0266 IclR family transcription regulator 24.71 1 5 5 14 4.561E7 12.78 15.69 3 6 707.96 24.71 5 8 255 27.7 6.05 HVO_0937 FMN-binding domain protein 24.66 1 2 2 6 6.142E7 2.87 24.66 2 3 221.98 24.66 2 3 146 16.2 4.36 HVO_2961 dihydrolipoyl dehydrogenase 24.63 1 8 8 39 3.269E8 50.59 24.63 8 19 3227.22 24.63 8 20 475 49.9 4.41 HVO_2759 peptidase M42 family protein 24.58 1 5 5 15 5.705E7 15.34 16.95 4 7 1022.65 24.58 5 8 354 37.0 4.40 HVO_0466 citrate (si)-synthase 24.54 1 8 8 41 5.551E8 39.73 23.22 7 20 2666.32 24.54 8 21 379 41.8 4.55 HVO_0552 DNA mismatch repair protein MutS 24.46 1 15 16 52 1.549E8 42.36 18.18 13 25 2737.56 23.05 15 27 924 99.2 4.65 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 24.41 1 4 4 9 7.405E7 5.59 19.29 3 4 471.35 24.41 4 5 254 26.9 4.42 HVO_0639 AAA-type ATPase (MoxR subfamily) 24.37 1 6 6 25 1.270E8 15.90 21.84 5 11 1242.63 24.37 6 14 316 34.7 4.89 HVO_2156 UspA domain protein 24.25 1 6 6 23 3.804E8 20.24 24.25 6 12 1627.64 24.25 6 11 301 31.6 4.69 HVO_1871 UPF0447 family protein 24.15 1 11 11 48 3.157E8 28.85 18.76 9 21 2376.98 24.15 11 27 501 56.1 4.59 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 24.11 1 5 5 22 5.074E8 12.34 19.37 4 10 1299.18 24.11 5 12 253 26.0 4.60 HVO_2562 50S ribosomal protein L23 24.10 1 2 2 6 5.176E7 5.09 24.10 2 3 421.09 24.10 2 3 83 9.4 5.48 HVO_1382 nascent polypeptide-associated complex protein 24.03 1 2 2 6 3.948E7 8.58 24.03 2 3 529.56 24.03 2 3 129 13.7 4.06 HVO_2333 conserved hypothetical protein 24.03 1 6 6 14 5.456E7 2.06 18.51 4 6 442.99 24.03 6 8 308 34.9 4.54 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 23.86 1 7 7 27 5.319E8 16.06 21.98 6 13 1610.58 23.86 7 14 373 40.2 4.44 HVO_0357 ACT domain protein 23.81 1 4 4 10 2.316E8 11.13 23.81 4 5 706.21 23.81 4 5 189 20.2 4.59 HVO_2256 DUF262 family protein 23.81 1 12 12 36 1.323E8 28.62 23.81 12 18 1775.38 23.81 12 18 462 54.9 4.89 HVO_0054 glycine--tRNA ligase 23.74 1 9 9 42 1.131E9 48.10 21.38 8 20 3169.95 21.21 8 22 594 64.9 4.21 HVO_1348 probable YjeF family carbohydrate kinase 23.64 1 8 8 34 1.145E8 30.31 23.64 8 17 2014.82 23.64 8 17 478 48.8 4.45 HVO_2717 alanine--tRNA ligase 23.62 1 7 7 32 2.458E8 27.37 20.60 6 14 2118.38 23.62 7 18 398 41.6 4.39 HVO_1816 dihydroorotase 23.54 1 10 10 40 1.658E8 24.54 23.54 10 20 1970.06 23.54 10 20 429 45.4 4.40 HVO_0697 PAC2 family protein 23.53 1 3 3 14 2.055E8 19.44 23.53 3 7 1204.71 23.53 3 7 255 27.4 4.08 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 23.53 1 3 3 10 1.655E8 7.19 23.53 3 5 438.44 23.53 3 5 238 24.7 4.15 HVO_1918 probable metallo-beta-lactamase family hydrolase 23.51 1 3 3 10 5.958E7 4.97 23.51 3 5 253.14 23.51 3 5 302 34.0 4.55 HVO_1048 phosphoribosylformylglycinamidine synthase 2 23.50 1 11 11 54 5.248E8 66.23 22.51 10 25 4206.69 23.50 11 29 702 72.9 4.18 HVO_2948 phenylalanine--tRNA ligase alpha subunit 23.45 1 7 7 27 2.455E8 15.26 23.45 7 13 1208.13 23.45 7 14 499 55.1 4.41 HVO_2436 malic enzyme (NADP) 23.44 1 13 16 61 1.766E8 52.65 21.70 14 29 3456.69 23.44 16 32 751 81.4 4.55 HVO_2168 AAA-type ATPase (MoxR subfamily) 23.40 1 5 5 17 7.736E7 14.46 23.40 5 8 846.15 23.40 5 9 329 35.9 4.54 HVO_0452 leucine--tRNA ligase 23.38 1 19 19 62 2.050E8 49.83 23.38 19 29 3992.94 23.38 19 33 958 109.5 4.37 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 23.38 1 5 5 12 8.314E7 10.99 16.02 3 5 807.65 23.38 5 7 231 25.0 4.25 HVO_2266 hypothetical protein 23.12 1 8 8 31 2.249E8 25.97 23.12 8 16 2016.19 17.04 7 15 493 56.7 4.54 HVO_1867 lysine--tRNA ligase 23.06 1 11 11 39 2.490E8 36.99 17.84 9 19 2385.31 23.06 11 20 555 62.1 4.46 HVO_1123 thioredoxin-disulfide reductase 22.92 1 8 8 39 6.244E8 27.32 19.77 7 17 2352.77 22.92 8 22 349 37.3 4.32 HVO_0017 conserved hypothetical protein 22.92 1 4 4 5 2.400E8 301.71 22.92 4 5 192 21.9 4.50 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 22.83 1 3 3 11 4.869E7 6.72 22.83 3 6 373.06 22.83 3 5 219 22.4 4.06 HVO_2130 IclR family transcription regulator 22.79 1 5 5 16 9.148E7 9.05 22.79 5 8 798.30 22.79 5 8 272 30.1 5.55 HVO_1847 oligoendopeptidase PepF 22.70 1 8 8 20 9.794E7 18.63 19.03 7 9 1224.96 22.70 8 11 599 68.5 4.41 HVO_1459 ThuA family protein 22.69 1 3 3 14 3.609E8 12.12 22.69 3 7 919.22 22.69 3 7 238 26.8 4.67 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 22.69 1 8 8 45 1.610E9 41.75 22.69 8 22 2667.86 22.69 8 23 357 40.3 4.40 HVO_2690 GFO family oxidoreductase 22.68 1 7 7 36 8.025E8 32.93 22.68 7 18 2196.09 22.68 7 18 366 40.0 4.60 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 22.62 1 6 6 16 7.497E7 7.88 22.62 6 8 642.67 20.33 5 8 305 34.1 4.91 HVO_0048 argininosuccinate lyase 22.54 1 8 8 24 9.612E7 19.12 19.88 7 11 1413.21 22.54 8 13 488 50.8 4.53 HVO_0970 ribulose-bisphosphate carboxylase large subunit 22.46 1 8 8 44 2.641E8 38.69 22.46 8 22 3017.11 22.46 8 22 414 43.9 4.59 HVO_1878 NAD synthase 22.46 1 6 6 38 4.907E8 30.62 22.46 6 19 2130.86 22.46 6 19 276 29.6 4.37 HVO_1570 DNA topoisomerase VI subunit A 22.40 1 5 5 21 2.869E8 7.05 22.40 5 9 1111.85 22.40 5 12 366 41.8 4.63 HVO_0795 transcription initiation factor TFB 22.39 1 6 6 17 8.040E7 13.93 22.39 6 9 798.93 22.39 6 8 335 37.4 5.59 HVO_2313 siroheme decarboxylase AhbB 22.38 1 5 5 20 1.308E8 25.75 22.38 5 10 1378.43 22.38 5 10 353 39.6 4.64 HVO_1531 UDP-glucose 6-dehydrogenase 22.33 1 9 9 33 1.523E8 18.61 22.33 9 17 1800.77 22.33 9 16 430 45.9 4.50 HVO_0788 tryptophan synthase beta subunit 22.27 1 6 6 25 1.859E8 27.83 22.27 6 12 1707.25 22.27 6 13 422 45.7 4.65 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 22.26 1 4 5 15 6.419E7 13.39 20.38 4 7 970.86 22.26 5 8 265 29.3 4.92 HVO_0321 peptide chain release factor aRF-1 22.22 1 10 10 34 1.759E8 28.08 20.29 9 17 2251.73 20.77 9 17 414 46.6 4.83 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 22.22 1 4 4 20 2.961E8 18.45 22.22 4 10 1641.46 22.22 4 10 324 33.6 3.99 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 22.22 1 6 6 17 3.908E8 8.26 19.17 5 8 866.06 22.22 6 9 360 38.5 4.45 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 22.17 1 6 6 20 8.636E7 11.45 22.17 6 10 902.08 22.17 6 10 442 46.9 4.58 47132620 keratin 2a [Homo sapiens] 22.07 1 8 14 53 4.756E8 49.52 22.07 13 26 3986.33 22.07 14 27 639 65.4 8.00 HVO_B0371 aldehyde dehydrogenase 21.98 1 5 5 22 8.137E7 29.16 21.98 5 11 1343.26 21.98 5 11 496 52.5 4.39 HVO_2580 L-aspartate oxidase 21.97 1 8 8 24 8.516E7 20.04 21.97 8 12 1118.35 21.97 8 12 537 55.8 4.63 HVO_0787 indole-3-glycerol-phosphate synthase 21.91 1 4 4 12 4.654E7 4.19 21.91 4 6 553.77 21.91 4 6 251 26.7 4.44 HVO_2008 archaeosine synthase 21.88 1 9 9 27 3.786E8 23.45 21.88 9 14 1336.36 21.88 9 13 585 64.9 4.81 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 21.84 1 5 5 19 1.318E8 10.05 21.84 5 9 600.41 21.84 5 10 348 36.7 4.69 HVO_2542 50S ribosomal protein L15 21.82 1 3 3 10 5.473E7 9.07 21.82 3 5 589.87 21.82 3 5 165 17.8 4.93 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 21.50 1 24 24 109 4.453E8 77.09 20.40 22 54 5345.78 21.50 24 55 1284 141.2 4.35 HVO_0429 archaemetzincin 21.39 1 2 2 6 3.739E7 2.46 21.39 2 3 304.62 21.39 2 3 173 19.3 6.54 HVO_0214 L-lactate dehydrogenase 21.25 1 7 7 44 1.413E9 40.36 21.25 7 22 3028.96 19.69 6 22 320 34.5 4.49 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 21.15 1 7 7 50 1.068E9 55.70 21.15 7 25 3745.91 21.15 7 25 435 46.9 4.63 HVO_1510 2-isopropylmalate synthase 21.14 1 6 6 24 7.447E8 23.45 21.14 6 13 1696.94 15.00 5 11 440 47.7 4.82 HVO_1575 arginase 21.07 1 4 4 12 9.770E7 7.34 21.07 4 6 555.00 21.07 4 6 299 31.0 4.58 HVO_2001 tRNA-guanine(15) transglycosylase 20.93 1 6 6 25 1.125E8 13.22 20.93 6 12 1212.68 20.93 6 13 516 56.3 4.59 HVO_B0055 conserved hypothetical protein 20.89 1 5 5 18 4.591E8 16.26 20.89 5 9 1243.27 20.89 5 9 225 23.9 4.69 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 20.88 1 2 2 6 6.555E7 6.70 20.88 2 3 340.23 20.88 2 3 91 10.4 4.07 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 20.87 1 7 7 21 1.657E8 11.28 20.87 7 10 974.82 20.87 7 11 345 36.9 4.68 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 20.75 1 7 7 48 4.814E8 49.75 20.75 7 24 3220.10 20.75 7 24 347 36.8 4.93 HVO_1453 glutamate dehydrogenase (NADP) 20.62 1 7 7 16 8.969E7 6.46 16.55 5 7 599.64 20.62 7 9 417 45.7 4.49 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 20.62 1 4 4 13 6.226E7 3.74 9.02 3 6 434.62 20.62 4 7 388 41.9 4.35 HVO_2790 ATP-binding protein Mrp 20.52 1 4 4 14 2.147E8 14.18 20.52 4 7 918.98 20.52 4 7 346 36.8 4.50 HVO_1125 cysteine--tRNA ligase 20.45 1 8 8 33 1.337E8 24.68 19.03 7 16 1909.32 20.45 8 17 494 55.2 4.56 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 20.43 1 18 18 69 2.781E8 62.62 20.43 18 34 4542.40 19.87 17 35 1082 117.2 4.32 HVO_1957 proteasome-activating nucleotidase 20.39 1 7 7 19 1.829E8 13.35 18.69 6 9 1233.87 20.39 7 10 412 45.6 4.48 HVO_0868 NAD-dependent epimerase/dehydratase 20.36 1 7 7 17 1.209E8 5.58 16.41 6 8 699.07 20.36 7 9 329 36.1 4.55 HVO_0911 GTP-binding protein Drg 20.33 1 5 5 15 4.175E7 7.41 15.72 4 7 603.11 20.33 5 8 369 40.5 4.81 HVO_1508 acetolactate synthase large subunit 20.10 1 8 8 43 2.481E8 46.46 20.10 8 21 2739.84 20.10 8 22 587 62.3 4.36 HVO_2952 tRNA-splicing endonuclease 20.06 1 4 4 11 5.502E7 7.39 20.06 4 5 500.84 20.06 4 6 339 37.4 4.74 HVO_2467 NADPH:quinone reductase 19.94 1 4 4 20 1.866E8 14.30 19.94 4 10 1184.05 19.94 4 10 321 33.0 4.51 HVO_1727 TATA-binding transcription initiation factor 19.89 1 4 4 13 7.929E8 17.53 19.89 4 6 1018.86 19.89 4 7 186 19.9 4.36 HVO_2688 TrmB family transcription regulator 19.83 1 6 6 25 5.207E8 26.83 18.13 5 12 1720.16 19.83 6 13 353 39.3 4.58 HVO_2779 50S ribosomal protein L18e 19.83 1 3 3 9 1.808E7 8.54 8.62 2 4 582.59 19.83 3 5 116 12.7 8.50 HVO_1323 "shikimate kinase, archaeal-type" 19.72 1 4 4 21 1.843E8 20.05 19.72 4 11 1358.52 19.72 4 10 289 29.5 4.30 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 19.71 1 3 3 9 7.435E7 7.70 19.71 3 4 298.46 19.71 3 5 208 22.6 4.36 HVO_A0485 aminotransferase class V 19.66 1 5 5 22 1.868E8 24.81 19.66 5 11 1628.23 19.66 5 11 351 37.3 4.26 HVO_1175 DUF2110 family protein 19.56 1 4 4 20 2.311E8 17.29 19.56 4 10 1392.63 19.56 4 10 225 24.4 4.63 HVO_1098 diaminopimelate decarboxylase 19.52 1 7 7 20 2.141E8 7.62 17.83 6 9 1020.44 19.52 7 11 415 44.4 5.02 HVO_0406 RNA-binding protein AU-1 19.44 1 6 6 16 1.169E8 8.01 13.25 4 7 732.57 19.44 6 9 468 49.9 4.53 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 19.44 1 5 5 20 1.638E8 8.76 19.44 5 10 1107.62 19.44 5 10 427 45.4 4.56 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 19 9.385E8 19.98 12.96 3 8 1735.95 19.31 5 11 378 39.7 4.67 HVO_0601 homoserine dehydrogenase 19.30 1 4 4 16 3.086E8 22.13 19.30 4 8 1432.88 19.30 4 8 316 32.2 4.25 HVO_1478 transcription initiation factor TFB 19.24 1 3 6 32 2.427E8 31.90 19.24 6 16 2110.41 19.24 6 16 317 35.7 5.47 HVO_0681 DNA topoisomerase I 19.17 1 13 13 38 1.136E8 26.68 19.17 13 20 1821.68 16.31 11 18 840 93.6 4.58 HVO_1685 conserved hypothetical protein 19.11 1 9 9 27 1.419E8 13.17 16.87 8 13 1137.94 19.11 9 14 492 54.5 5.74 HVO_2965 phosphoserine phosphatase 19.07 1 2 2 8 6.398E7 0.00 19.07 2 4 209.68 19.07 2 4 215 23.2 4.51 HVO_1879 enoyl-CoA hydratase 19.05 1 3 3 9 3.873E7 4.29 19.05 3 4 368.97 19.05 3 5 231 24.3 5.21 HVO_A0087 fumarylacetoacetase family protein 19.03 1 4 4 11 1.522E8 11.93 17.30 3 5 639.26 19.03 4 6 289 32.0 4.21 HVO_1289 OsmC domain protein 18.94 1 2 2 37 8.938E8 50.10 18.94 2 18 3572.20 18.94 2 19 132 14.2 3.85 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 18.91 1 7 7 24 2.335E8 21.22 18.91 7 12 1455.66 18.91 7 12 423 43.9 4.31 HVO_0034 acyl-CoA thioester hydrolase 18.90 1 3 3 17 1.767E8 16.92 18.90 3 9 869.09 18.90 3 8 164 18.3 4.65 HVO_2648 phosphoglycerate dehydrogenase 18.81 1 4 4 12 9.259E7 11.59 18.81 4 6 813.60 18.81 4 6 319 34.2 4.64 HVO_1020 HEAT-PBS family protein 18.62 1 6 6 25 1.767E8 28.31 18.62 6 12 2086.89 18.62 6 13 419 45.5 3.95 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 18.57 1 3 3 11 8.363E7 5.06 18.57 3 5 383.00 18.57 3 6 377 39.2 4.18 HVO_0541 aconitate hydratase 18.55 1 11 11 34 2.158E8 13.06 16.74 10 17 1168.85 18.55 11 17 938 102.1 4.40 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 18.54 1 8 8 39 3.198E8 34.74 18.54 8 19 2380.57 18.54 8 20 615 67.6 4.88 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 18.40 1 4 4 13 8.290E7 10.02 18.40 4 6 900.50 18.40 4 7 337 35.9 4.69 HVO_2883 conserved hypothetical protein 18.38 1 9 9 31 7.762E7 15.90 18.38 9 15 1456.70 18.38 9 16 702 78.9 4.48 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 18.37 1 13 13 42 1.154E8 37.98 17.37 12 21 2402.26 18.37 13 21 898 97.7 4.45 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 14 2.378E8 17.51 18.29 4 7 1098.06 18.29 4 7 257 26.8 4.01 HVO_2321 bacterial-type DNA primase DnaG 18.01 1 6 6 12 6.170E7 3.59 18.01 6 7 457.10 12.71 4 5 472 49.4 4.36 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 17.84 1 3 3 10 1.708E8 10.15 17.84 3 5 805.53 17.84 3 5 269 28.3 4.49 HVO_1503 3-isopropylmalate dehydratase small subunit 17.82 1 3 3 17 1.527E8 14.62 17.82 3 9 610.38 17.82 3 8 202 22.0 4.15 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 17.79 1 9 10 47 5.498E8 40.75 17.79 10 23 3476.70 17.79 10 24 697 74.5 4.13 HVO_1623 conserved hypothetical protein 17.79 1 4 4 11 4.318E7 4.94 14.77 3 5 476.57 17.79 4 6 298 32.8 4.56 HVO_1965 rRNA maturation endonuclease Nob1 17.76 1 2 2 4 3.569E7 2.14 17.76 2 2 187.29 17.76 2 2 152 16.8 4.70 HVO_1553 hydroxypyruvate reductase 17.65 1 6 6 21 8.227E7 15.69 17.65 6 10 1198.75 17.65 6 11 442 45.2 4.50 HVO_2639 DUF1611 family protein 17.60 1 4 4 19 1.055E8 26.31 17.60 4 9 1472.92 17.60 4 10 341 36.3 4.44 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 17.53 1 4 4 11 8.705E7 6.70 12.33 3 5 593.72 17.53 4 6 365 39.0 4.61 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 17.46 1 5 5 13 7.927E7 7.03 17.46 5 7 497.87 10.58 4 6 378 39.8 4.45 HVO_1354 DNA mismatch repair protein MutS 17.41 1 9 9 20 1.321E8 9.35 16.03 8 10 830.39 15.52 8 10 580 62.1 4.56 HVO_1500 1-phosphofructokinase 17.38 1 5 5 16 4.468E7 12.75 13.77 4 8 753.10 13.77 4 8 305 32.0 4.51 HVO_0894 acyl-CoA synthetase 17.37 1 5 8 27 1.086E8 17.39 15.86 7 13 1542.27 14.35 7 14 662 74.3 4.48 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 17.36 1 6 6 28 1.657E8 16.16 17.36 6 14 1612.39 17.36 6 14 363 39.3 4.97 HVO_2205 arNOG06768 family NADH-binding domain protein 17.28 1 4 4 10 4.616E7 11.95 17.28 4 5 577.18 17.28 4 5 301 32.0 5.00 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 17.23 1 3 4 20 8.050E7 18.16 17.23 4 10 1234.60 17.23 4 10 267 28.8 4.55 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 17.19 1 7 7 22 1.474E8 22.38 17.19 7 11 1334.15 17.19 7 11 634 66.1 4.54 HVO_1547 isoleucine--tRNA ligase 17.16 1 16 16 69 4.733E8 56.89 17.16 16 35 3665.76 17.16 16 34 1043 117.9 4.30 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 17.15 1 4 4 15 5.605E7 13.20 13.95 3 7 1170.62 17.15 4 8 344 39.1 4.73 HVO_2347 conserved hypothetical protein 17.14 1 2 2 8 1.623E7 9.14 17.14 2 4 496.23 17.14 2 4 140 15.5 4.37 HVO_1080 conserved hypothetical protein 17.02 1 4 4 13 2.599E8 7.11 12.77 3 6 564.54 17.02 4 7 188 21.1 4.31 HVO_1550 acyl-CoA thioester hydrolase 16.88 1 2 2 8 1.208E8 8.15 16.88 2 4 470.11 16.88 2 4 160 17.6 4.55 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 16.86 1 7 7 20 5.916E7 12.76 14.34 6 9 1023.09 16.86 7 11 516 56.7 4.89 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 16.78 1 5 5 19 6.918E7 15.37 13.94 4 9 828.43 16.78 5 10 459 50.5 4.63 HVO_0469 AstE family protein 16.67 1 4 4 9 1.092E8 4.57 16.67 4 4 378.85 16.67 4 5 318 33.9 5.85 HVO_B0382 TATA-binding transcription initiation factor 16.49 1 2 2 6 3.733E7 2.50 16.49 2 3 204.08 16.49 2 3 188 20.1 4.12 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 16.33 1 3 3 8 4.054E7 5.88 16.33 3 4 308.42 16.33 3 4 294 32.5 4.75 HVO_0977 N5-carboxyaminoimidazole ribonucleotide mutase 16.26 1 2 2 4 2.107E7 4.71 16.26 2 2 211.18 16.26 2 2 203 21.5 4.36 HVO_0180 23S rRNA (uridine-2'-O-) methyltransferase 16.22 1 3 3 8 5.962E7 2.26 16.22 3 3 247.29 16.22 3 5 259 28.3 4.70 HVO_0818 threonine synthase 16.20 1 5 5 22 2.357E8 15.27 16.20 5 11 1074.64 16.20 5 11 389 40.8 4.31 HVO_1579 uridine phosphorylase 16.18 1 2 2 6 7.707E7 4.63 16.18 2 3 326.07 16.18 2 3 272 29.0 4.64 HVO_2702 alpha/beta hydrolase fold protein 16.15 1 4 4 21 1.149E8 15.18 16.15 4 10 1111.86 16.15 4 11 260 28.0 4.53 HVO_2756 50S ribosomal protein L10 16.09 1 5 5 22 2.334E8 14.14 13.51 4 10 1306.23 16.09 5 12 348 36.9 3.99 HVO_2554 50S ribosomal protein L14 15.91 1 3 3 8 6.360E7 4.30 15.91 3 4 374.60 15.91 3 4 132 14.2 9.76 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 15.90 1 4 4 9 2.334E7 5.73 15.90 4 5 297.15 15.90 4 4 327 36.2 4.63 HVO_0745 "FtsZ family protein, type III" 15.83 1 4 4 13 4.072E7 8.21 15.83 4 7 572.97 15.83 4 6 360 37.1 4.51 HVO_B0060 precorrin-4 C11-methyltransferase 15.77 1 3 3 23 5.200E8 14.41 15.77 3 11 1067.86 15.77 3 12 279 29.7 4.22 HVO_A0133 conserved hypothetical protein 15.75 1 4 4 11 7.898E7 12.16 14.04 3 5 820.96 15.75 4 6 292 30.8 5.17 HVO_1979 tRNA pseudouridine synthase Pus10 15.69 1 6 6 28 3.982E8 13.09 15.69 6 14 1236.41 15.69 6 14 427 46.9 4.39 HVO_2712 3'-5' RNA ligase 15.64 1 6 6 22 7.660E7 17.98 15.64 6 11 1245.25 15.64 6 11 486 53.4 4.92 HVO_2536 CHP00300 family protein 15.63 1 4 4 13 1.643E8 4.72 13.70 3 6 458.50 15.63 4 7 416 44.8 4.51 HVO_1866 uridylate kinase 15.61 1 3 3 19 4.133E8 19.11 15.61 3 9 1297.89 15.61 3 10 237 24.6 4.42 HVO_0044 acetylglutamate kinase 15.60 1 4 4 10 3.296E8 7.89 15.60 4 5 757.12 15.60 4 5 327 33.2 4.49 HVO_2913 superoxide dismutase (Mn) 15.58 1 0 3 22 1.787E9 24.75 15.58 3 11 1764.31 15.58 3 11 199 22.3 4.48 HVO_2662 homolog to lactoylglutathione lyase 15.50 1 4 4 20 1.202E8 12.71 15.50 4 10 1112.12 15.50 4 10 329 36.5 4.48 HVO_A0475 superoxide dismutase (Mn) 15.50 1 0 3 22 1.787E9 24.75 15.50 3 11 1764.31 15.50 3 11 200 22.4 4.45 HVO_1698 CBS/parB domain protein 15.47 1 3 3 6 1.681E7 4.21 15.47 3 3 258.46 15.47 3 3 265 29.4 4.92 HVO_1804 nicotinate phosphoribosyltransferase 15.46 1 5 5 17 1.373E8 17.57 12.37 4 8 1404.54 15.46 5 9 388 41.1 4.60 HVO_1723 DNA repair helicase Rad25 15.40 1 8 8 21 4.021E7 13.80 14.53 7 10 964.94 15.40 8 11 695 76.8 4.69 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 15.38 1 5 5 34 2.134E8 37.39 13.15 4 16 2337.22 15.38 5 18 403 41.1 4.73 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 15.34 1 4 4 12 1.013E8 10.67 15.34 4 7 700.18 10.62 3 5 339 38.1 4.50 HVO_A0498 conserved hypothetical protein 15.30 1 6 6 13 8.031E7 1.94 12.93 4 5 596.48 15.30 6 8 379 42.7 4.55 HVO_1562 proteasome beta subunit 15.23 1 4 4 17 6.754E7 17.95 13.17 3 8 1282.35 15.23 4 9 243 26.0 4.63 HVO_0195 ribose-5-phosphate isomerase 15.22 1 3 3 14 1.488E8 12.21 15.22 3 7 721.12 15.22 3 7 230 23.2 4.54 HVO_C0046 conserved hypothetical protein 15.22 1 0 2 2 3.450E7 4.26 15.22 2 2 184 20.1 4.42 HVO_C0081 conserved hypothetical protein 15.22 1 0 2 2 3.450E7 4.26 15.22 2 2 184 20.2 4.40 HVO_1885 TrkA domain protein 15.21 1 2 2 2 1.391E7 80.35 15.21 2 2 217 23.4 4.75 HVO_1083 glucose 1-dehydrogenase 15.13 1 4 4 12 4.242E7 8.69 15.13 4 6 552.81 15.13 4 6 357 39.0 4.73 HVO_1079 sulfate adenylyltransferase small subunit 15.08 1 4 4 20 3.201E8 20.84 8.62 3 9 1325.16 15.08 4 11 325 37.5 4.18 HVO_2029 Lrp/AsnC family transcription regulator 15.03 1 2 2 8 1.076E8 1.83 15.03 2 4 270.77 15.03 2 4 153 16.9 4.21 HVO_2960 dihydrolipoamide S-acyltransferase 14.97 1 6 6 26 1.426E8 24.38 14.97 6 13 1490.61 14.97 6 13 521 54.9 4.40 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 14.94 1 3 3 10 4.224E7 8.49 14.94 3 5 540.81 14.94 3 5 241 26.1 4.58 HVO_2763 homolog to ribonuclease Z 14.92 1 3 3 13 1.035E8 6.49 14.92 3 7 629.71 14.92 3 6 248 26.6 4.53 HVO_B0143 receiver/sensor box histidine kinase 14.91 1 7 7 20 6.960E7 12.28 10.05 5 9 1014.62 14.91 7 11 597 66.0 4.41 HVO_B0200 malate synthase 14.91 1 4 4 11 1.194E8 9.21 14.91 4 5 524.21 14.91 4 6 436 48.3 4.30 HVO_1711 glucoamylase 14.89 1 16 16 50 6.326E7 29.13 12.91 15 24 2287.14 14.89 16 26 1511 166.1 4.64 HVO_C0069 GFO family oxidoreductase 14.81 1 5 5 18 6.683E7 11.59 14.81 5 9 879.88 14.81 5 9 324 36.0 5.10 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 14.80 1 3 3 4 1.216E8 512.91 14.80 3 4 277 30.6 4.30 HVO_1783 conserved hypothetical protein 14.73 1 2 2 3 3.486E7 176.89 14.73 2 3 224 24.1 5.90 HVO_0042 acetylornithine deacetylase 14.70 1 5 5 18 2.358E8 8.61 14.70 5 9 912.19 14.70 5 9 381 41.0 4.34 HVO_2793 conserved hypothetical protein 14.68 1 3 3 6 1.004E8 5.15 14.68 3 3 332.28 14.68 3 3 252 27.1 4.46 HVO_0402 DUF124 family protein 14.67 1 2 2 7 2.802E8 3.72 14.67 2 4 198.32 14.67 2 3 225 24.0 4.58 HVO_2153 probable copper-containing oxidoreductase 14.55 1 4 4 18 8.728E7 16.52 14.55 4 9 1179.85 14.55 4 9 385 42.1 5.82 HVO_1179 homolog to NAD kinase 14.41 1 3 3 4 1.378E8 3.56 8.19 2 2 101.47 9.89 2 2 354 36.7 4.60 HVO_1928 5-formyltetrahydrofolate cyclo-ligase 14.40 1 3 3 7 2.126E7 5.49 14.40 3 3 357.66 14.40 3 4 243 26.5 4.69 HVO_2373 30S ribosomal protein S8e 14.40 1 2 2 5 5.066E7 1.76 14.40 2 3 125.85 14.40 2 2 125 13.6 10.48 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 14.29 1 4 4 16 5.773E7 9.59 14.29 4 8 871.39 14.29 4 8 406 43.1 4.60 HVO_2543 50S ribosomal protein L30 14.29 1 2 2 5 2.462E7 0.00 14.29 2 2 180.31 14.29 2 3 154 17.1 4.77 HVO_A0003 ParA domain protein 14.23 1 3 3 12 3.934E7 8.26 14.23 3 6 613.21 14.23 3 6 274 30.3 4.53 HVO_1536 phosphoglycolate phosphatase 14.16 1 2 2 6 3.079E7 5.30 14.16 2 3 331.07 14.16 2 3 226 24.1 4.27 HVO_A0406 conserved hypothetical protein 14.07 1 1 4 14 1.391E8 3.52 14.07 4 7 522.83 14.07 4 7 405 44.4 5.30 HVO_0123 signal recognition particle 54K protein 13.98 1 6 6 25 1.791E8 18.78 11.83 5 11 1482.43 13.98 6 14 465 50.9 4.50 HVO_1299 HTH domain protein 13.87 1 2 2 4 5.001E7 2.70 13.87 2 2 262.45 13.87 2 2 173 18.9 4.84 HVO_2758 50S ribosomal protein L11 13.84 1 2 2 3 1.536E8 196.57 13.84 2 3 159 16.8 4.04 HVO_0854 DNA double-strand break repair ATPase Rad50 13.77 1 12 12 36 4.558E7 24.88 11.31 11 18 1623.80 13.77 12 18 893 100.0 4.58 HVO_0511 NAD-dependent epimerase/dehydratase 13.74 1 3 3 26 6.955E7 15.36 13.74 3 13 1265.30 13.74 3 13 262 29.3 4.78 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 13.68 1 4 4 10 7.407E7 4.72 10.94 3 4 441.16 13.68 4 6 329 36.3 4.49 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 14 5.387E8 4.90 13.66 2 7 698.91 13.66 2 7 183 20.0 4.21 HVO_1235 creatininase 13.64 1 3 3 9 4.527E7 7.14 13.64 3 5 529.91 7.95 2 4 264 29.2 4.84 HVO_0866 homolog to alanine-tRNA ligase 13.52 1 2 2 6 2.591E7 7.71 13.52 2 3 370.18 13.52 2 3 244 27.1 4.74 HVO_1087 UspA domain protein 13.48 1 2 2 6 5.564E7 4.24 13.48 2 3 272.84 13.48 2 3 141 15.2 4.98 HVO_0572 lipoate-protein ligase 13.45 1 3 3 10 7.618E7 11.15 13.45 3 5 891.02 13.45 3 5 275 30.5 4.84 HVO_1937 "probable 5,10-methylenetetrahydrofolate reductase" 13.41 1 3 3 9 4.605E7 4.32 13.41 3 5 401.16 10.06 2 4 328 34.5 4.63 HVO_2239 UspA domain protein 13.38 1 2 2 6 1.238E8 6.21 13.38 2 3 368.17 13.38 2 3 142 15.4 4.16 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 13.36 1 4 4 10 9.804E7 6.61 13.36 4 5 422.42 13.36 4 5 464 53.1 4.54 HVO_1501 DeoR family transcription regulator GlpR 13.33 1 3 3 8 4.807E7 4.30 13.33 3 4 367.50 13.33 3 4 255 28.0 4.97 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 13.33 1 4 4 7 2.158E7 3.45 13.33 4 4 303.12 10.95 3 3 420 45.0 4.86 HVO_2348 GTP cyclohydrolase MptA 13.31 1 3 3 27 2.098E8 17.24 13.31 3 13 1254.46 13.31 3 14 308 33.5 4.68 HVO_A0388 Lrp/AsnC family transcription regulator 13.22 1 2 2 2 3.543E7 118.24 13.22 2 2 174 20.1 4.86 HVO_0240 Lrp/AsnC family transcription regulator 13.16 1 2 2 3 2.481E8 453.91 13.16 2 3 152 16.9 4.39 HVO_2699 homolog to peroxiredoxin 13.16 1 2 2 3 1.945E7 282.17 13.16 2 3 152 16.7 4.09 HVO_1710 alpha amylase 13.15 1 9 9 24 1.460E8 12.10 13.15 9 13 1057.45 8.86 7 11 677 75.0 4.45 HVO_1150 IS200-type transposase 13.08 1 2 2 2 4.245E7 93.86 13.08 2 2 130 14.7 5.49 HVO_1337 rpa-associated protein 13.00 1 5 5 18 3.609E8 15.99 13.00 5 9 1027.57 13.00 5 9 623 64.8 3.68 HVO_2244 fumarylacetoacetase family protein 12.97 1 2 2 3 1.366E7 4.88 12.97 2 3 239 26.1 4.07 HVO_2548 50S ribosomal protein L6 12.92 1 2 2 6 3.636E7 4.87 12.92 2 3 320.60 12.92 2 3 178 19.6 4.68 HVO_A0547 DUF1028 family protein 12.91 1 4 4 11 1.241E8 4.44 12.91 4 5 448.78 12.91 4 6 333 35.2 4.16 HVO_2072 S-layer glycoprotein 12.82 1 5 5 37 1.828E9 32.50 12.82 5 19 1725.40 12.82 5 18 827 85.1 3.65 HVO_0699 translation initiation factor aIF-2 alpha subunit 12.78 1 4 4 16 2.201E8 16.97 12.78 4 8 1140.08 12.78 4 8 266 29.5 4.46 HVO_1268 conserved hypothetical protein 12.66 1 2 2 6 2.642E7 5.75 12.66 2 3 288.13 12.66 2 3 237 26.4 5.21 HVO_2716 acyl-CoA dehydrogenase 12.60 1 3 3 7 1.785E7 9.86 10.24 2 3 554.03 12.60 3 4 381 41.3 4.65 HVO_0087 porphobilinogen synthase 12.54 1 4 4 14 1.781E8 13.59 12.54 4 7 816.03 12.54 4 7 327 35.3 4.72 HVO_2600 methionyl aminopeptidase 12.50 1 5 5 18 2.161E8 14.80 8.45 4 8 1031.39 12.50 5 10 296 32.3 4.41 HVO_A0486 hydrogenase expression/formation protein 12.50 1 2 2 8 5.562E7 5.31 12.50 2 4 355.44 12.50 2 4 336 33.8 4.06 HVO_1683 4-alpha-glucanotransferase 12.50 1 6 6 19 1.245E8 12.04 10.48 5 9 849.99 12.50 6 10 496 56.3 4.45 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 12.38 1 3 3 9 4.324E7 1.85 12.38 3 4 351.47 12.38 3 5 323 34.9 5.24 HVO_1657 phosphoribosylamine--glycine ligase 12.38 1 7 7 44 9.361E8 28.87 9.58 5 20 2763.27 12.38 7 24 428 45.5 4.20 HVO_B0115 fumarylacetoacetase family protein 12.37 1 3 3 10 2.190E8 9.29 12.37 3 5 491.43 12.37 3 5 283 30.3 4.21 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 12.33 1 4 4 15 3.626E8 13.73 12.33 4 8 752.78 12.33 4 7 430 44.2 4.37 HVO_A0012 hypothetical protein 12.08 1 2 2 9 1.016E8 6.42 12.08 2 4 458.49 12.08 2 5 149 17.7 4.54 HVO_2784 30S ribosomal protein S13 11.98 1 2 2 8 8.671E7 6.55 11.98 2 4 417.31 11.98 2 4 167 18.9 5.17 HVO_0491 FMN-binding domain protein 11.76 1 2 2 3 1.610E7 182.51 11.76 2 3 153 17.3 4.67 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 11.75 1 4 4 20 6.138E7 14.87 11.75 4 9 923.72 11.75 4 11 349 37.0 4.70 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 6 2.784E8 1.65 11.64 2 3 241.84 11.64 2 3 189 20.3 4.22 HVO_2551 50S ribosomal protein L5 11.63 1 2 2 6 7.451E6 2.60 11.63 2 3 237.18 11.63 2 3 172 19.1 4.78 HVO_3000 DNA ligase (NAD) 11.59 1 5 6 22 2.896E8 17.26 11.59 6 10 1081.78 11.59 6 12 699 75.8 4.50 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 11.57 1 3 3 7 2.647E7 1.65 11.57 3 3 187.96 11.57 3 4 268 27.9 4.87 HVO_1375 O-succinylbenzoic acid--CoA ligase 11.56 1 5 5 10 6.961E7 10.08 11.56 5 5 506.31 11.56 5 5 614 64.7 4.28 HVO_1880 conserved hypothetical protein 11.56 1 2 2 6 1.727E7 7.75 11.56 2 3 532.31 11.56 2 3 225 23.8 4.59 HVO_0414 peptidase M24 family protein 11.52 1 2 2 3 4.665E7 285.33 11.52 2 3 382 39.4 4.82 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 11.50 1 3 3 8 2.485E7 5.90 11.50 3 4 298.31 11.50 3 4 287 31.8 4.93 HVO_1629 conserved hypothetical protein 11.49 1 5 5 11 4.963E7 3.80 7.16 3 5 388.40 11.49 5 6 531 56.3 4.69 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 11.43 1 2 2 8 5.985E7 8.58 11.43 2 4 432.30 11.43 2 4 175 18.8 4.63 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 11.37 1 3 3 7 3.578E7 7.83 6.53 2 3 628.36 11.37 3 4 475 49.3 4.49 HVO_2383 DNA repair and recombination protein RadB 11.35 1 3 3 7 2.328E7 6.42 10.92 2 3 427.49 11.35 3 4 229 24.6 5.02 HVO_A0583 IclR family transcription regulator 11.33 1 3 3 6 1.908E7 0.00 7.03 2 2 310.40 11.33 3 4 256 27.9 5.07 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 11.29 1 3 3 13 1.435E8 11.19 11.29 3 7 851.12 9.92 2 6 363 39.7 4.25 HVO_2427 replication factor C large subunit 11.27 1 5 5 16 2.732E7 16.08 11.27 5 8 1099.38 11.27 5 8 488 53.4 4.67 HVO_2605 MiaB-like tRNA modifying enzyme 11.19 1 4 4 9 1.868E7 0.00 11.19 4 4 270.82 11.19 4 5 429 47.4 5.03 HVO_1704 homolog to arabinopyranose mutase 11.17 1 4 4 8 5.434E7 5.33 9.35 3 4 496.50 6.75 3 4 385 43.4 4.23 HVO_0979 NADH dehydrogenase-like complex subunit B 11.16 1 2 2 6 6.956E7 3.90 11.16 2 3 240.09 11.16 2 3 233 26.1 5.01 HVO_2918 thymidylate synthase 11.14 1 2 2 8 5.100E7 3.99 11.14 2 4 259.58 11.14 2 4 332 37.5 4.61 HVO_0837 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 11.11 1 2 2 3 3.991E7 258.81 11.11 2 3 243 24.8 4.48 HVO_1038 uracil-DNA glycosylase superfamily protein 11.06 1 2 2 6 4.410E7 1.68 11.06 2 3 198.51 11.06 2 3 208 22.7 4.61 HVO_B0117 conserved hypothetical protein 11.06 1 2 2 7 7.914E7 4.05 11.06 2 4 286.73 11.06 2 3 208 23.3 4.58 HVO_0120 signal recognition particle receptor FtsY 10.96 1 4 4 10 1.948E7 7.33 10.96 4 5 723.98 10.96 4 5 456 48.2 4.17 HVO_C0001 Orc1-type DNA replication protein 10.78 1 5 5 18 7.280E7 12.00 10.78 5 9 735.28 10.78 5 9 408 45.2 4.97 HVO_A0635 probable cysteine desulfurase 10.78 1 2 2 2 3.091E7 131.86 10.78 2 2 371 40.4 4.53 HVO_A0288 probable oxidoreductase (short-chain dehydrogenase family) 10.71 1 2 2 5 2.800E7 1.60 10.71 2 2 260.69 10.71 2 3 280 29.9 4.74 HVO_1567 conserved hypothetical protein 10.64 1 2 2 8 1.960E8 7.68 10.64 2 4 609.79 10.64 2 4 235 25.7 4.36 HVO_1914 acetyl-CoA C-acyltransferase 10.61 1 3 3 6 5.175E7 0.00 7.96 2 2 224.87 10.61 3 4 377 39.9 4.41 HVO_2945 valine--tRNA ligase 10.57 1 7 7 38 1.921E8 42.25 9.08 6 18 3073.53 10.57 7 20 870 98.9 4.36 HVO_0551 DNA mismatch repair protein MutL 10.48 1 6 6 24 6.914E7 16.59 10.48 6 12 1248.66 10.48 6 12 735 78.7 4.50 HVO_A0586 sugar nucleotidyltransferase 10.46 1 3 3 10 6.850E7 9.01 10.46 3 5 586.10 10.46 3 5 411 43.7 4.69 HVO_0826 peptidase M42 family protein 10.34 1 3 3 10 3.268E7 9.28 10.34 3 5 567.14 10.34 3 5 348 37.7 4.54 HVO_0741 DNA-directed DNA polymerase X 10.31 1 4 4 8 4.392E7 1.67 8.25 3 4 211.47 10.31 4 4 582 62.6 4.44 HVO_0580 putative tRNA 2-thiolation protein 10.28 1 2 2 2 6.493E7 37.83 10.28 2 2 321 36.1 5.01 HVO_2096 NAD-dependent epimerase/dehydratase 10.28 1 2 2 2 2.426E8 70.05 10.28 2 2 214 22.2 4.42 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 10.24 1 3 3 7 1.082E8 6.04 5.25 2 3 447.61 10.24 3 4 381 40.5 4.51 HVO_2227 siroheme decarboxylase AhbA 10.09 1 3 3 6 3.699E7 3.81 10.09 3 3 403.66 10.09 3 3 347 39.1 4.69 HVO_2923 proteasome alpha subunit 10.04 1 1 2 8 2.929E8 4.30 10.04 2 4 351.65 10.04 2 4 249 26.7 4.39 HVO_0867 HD family hydrolase 10.00 1 2 2 10 8.646E7 11.04 10.00 2 5 643.65 10.00 2 5 230 26.2 4.78 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 12 1.940E8 8.26 10.00 2 6 674.53 10.00 2 6 190 21.0 4.74 HVO_1936 F420-0:gamma-glutamyl ligase 9.96 1 2 2 8 4.115E7 3.92 9.96 2 4 360.24 9.96 2 4 251 27.4 4.68 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 9.96 1 2 2 3 1.094E8 226.49 9.96 2 3 261 27.0 4.44 HVO_0014 ATP-dependent DNA helicase Hel308a 9.92 1 7 7 26 7.925E7 11.61 9.92 7 13 1209.34 9.92 7 13 827 90.3 4.67 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 9.88 1 5 5 12 5.356E7 8.27 9.88 5 6 541.14 9.88 5 6 658 72.1 4.70 HVO_1625 conserved hypothetical protein 9.79 1 4 4 18 5.503E7 27.21 9.79 4 9 1682.53 9.79 4 9 654 70.1 4.04 HVO_0019 probable S-adenosylmethionine-dependent methyltransferase (homolog to 24-sterol C-methyltransferase) 9.73 1 2 2 12 5.803E7 10.57 9.73 2 5 599.61 9.73 2 7 226 25.6 4.64 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 9.72 1 3 3 16 1.187E8 11.00 9.72 3 8 600.33 9.72 3 8 360 39.5 4.31 HVO_0135 RIO-type serine/threonine protein kinase 9.66 1 3 3 8 3.342E7 4.33 9.66 3 4 359.93 9.66 3 4 290 33.0 4.81 HVO_0476 conserved hypothetical protein 9.63 1 2 2 8 5.271E7 12.04 9.63 2 4 654.16 9.63 2 4 218 23.8 4.60 HVO_A0458 ParA domain protein 9.62 1 2 2 3 5.419E7 218.99 9.62 2 3 291 32.2 4.79 HVO_2761 mevalonate kinase 9.54 1 3 3 6 3.886E7 3.96 4.90 2 2 219.95 9.54 3 4 367 38.2 4.31 HVO_1656 YyaL family protein 9.53 1 7 7 23 5.363E7 16.74 9.53 7 11 996.14 9.53 7 12 703 77.3 4.49 HVO_2873 flap endonuclease Fen1 9.51 1 3 3 12 5.365E7 13.65 9.51 3 6 869.64 9.51 3 6 326 36.4 4.40 HVO_2501 alpha/beta hydrolase fold protein 9.49 1 2 2 8 2.255E7 9.08 9.49 2 4 479.35 9.49 2 4 316 35.3 5.72 HVO_2932 GTP-binding protein 9.34 1 3 3 8 8.869E7 1.66 9.34 3 4 321.97 9.34 3 4 396 43.5 4.51 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 9.33 1 3 3 12 2.108E8 8.04 9.33 3 6 659.69 9.33 3 6 386 42.1 4.49 HVO_1055 TrkA domain protein 9.29 1 2 2 3 2.286E7 306.22 9.29 2 3 226 24.4 4.39 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 9.26 1 3 3 14 7.135E7 12.97 9.26 3 7 918.66 9.26 3 7 324 36.6 4.68 HVO_1128 sirohydrochlorin cobaltochelatase 9.25 1 3 3 8 4.031E7 1.70 9.25 3 4 355.74 9.25 3 4 292 32.3 4.42 HVO_2068 "FtsZ family protein, type III" 9.19 1 2 2 6 1.048E8 6.15 9.19 2 3 459.47 9.19 2 3 370 38.7 4.49 HVO_0507 creatininase 9.17 1 2 2 8 3.111E7 0.00 9.17 2 4 351.32 9.17 2 4 240 25.6 4.56 HVO_0484 50S ribosomal protein L10e 9.09 1 2 2 6 2.011E7 1.65 9.09 2 3 285.67 9.09 2 3 176 19.8 8.72 HVO_2697 DNA primase small subunit 9.09 1 3 3 5 2.011E7 0.00 7.27 2 2 147.32 9.09 3 3 385 42.6 4.72 HVO_A0150 TrmB family transcription regulator 9.04 1 3 3 7 9.757E7 2.15 9.04 3 3 249.82 9.04 3 4 354 39.0 4.63 HVO_1139 squalene synthase 8.94 1 2 2 8 3.306E7 11.19 8.94 2 4 555.68 8.94 2 4 358 39.7 4.54 HVO_2564 50S ribosomal protein L3 8.88 1 2 2 4 3.251E7 4.83 8.88 2 2 229.02 8.88 2 2 338 37.2 6.68 HVO_2581 quinolinate synthase A 8.83 1 3 3 12 1.067E8 3.90 8.83 3 6 466.02 8.83 3 6 385 42.0 4.41 HVO_C0077 sarcosine oxidase 8.79 1 2 2 3 4.776E7 0.00 8.79 2 3 387 42.9 4.70 HVO_B0114 IclR family transcription regulator 8.73 1 2 2 4 1.164E7 2.23 8.73 2 2 151.80 8.73 2 2 252 28.4 5.44 HVO_1746 DUF2800 family protein 8.67 1 2 2 6 4.890E7 3.72 8.67 2 3 220.99 8.67 2 3 323 36.5 4.37 HVO_0719 transcription elongation factor Spt5/NusG 8.67 1 2 2 3 4.843E7 234.27 8.67 2 3 150 16.3 4.50 HVO_1368 probable metallo-beta-lactamase family hydrolase 8.61 1 2 2 10 2.344E8 7.37 8.61 2 5 532.51 8.61 2 5 267 29.3 4.49 HVO_1716 7-cyano-7-deazaguanine synthase 8.61 1 2 2 4 5.650E7 0.00 8.61 2 2 144.91 8.61 2 2 244 26.8 4.42 HVO_0733 transcription initiation factor TFB 8.59 1 0 3 10 1.965E8 9.84 8.59 3 5 496.85 8.59 3 5 326 37.2 6.00 HVO_0339 tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS 8.53 1 2 2 3 3.452E6 4.62 8.53 2 3 422 45.5 5.21 HVO_A0432 conserved hypothetical protein 8.40 1 0 3 10 1.182E8 3.52 8.40 3 5 472.90 8.40 3 5 405 44.5 5.24 HVO_0687 M20 family amidohydrolase 8.33 1 3 3 12 4.535E7 6.08 8.33 3 6 441.60 8.33 3 6 444 47.5 4.58 HVO_2951 tryptophan--tRNA ligase 8.32 1 3 3 8 3.111E7 1.92 8.32 3 4 234.84 8.32 3 4 529 59.1 4.53 HVO_1995 conserved hypothetical protein 8.23 1 2 2 6 2.669E7 4.01 8.23 2 3 247.43 8.23 2 3 243 26.5 4.39 HVO_2727 cyclase family protein 8.22 1 2 2 4 2.175E7 1.60 8.22 2 2 139.82 8.22 2 2 219 23.6 4.74 HVO_1129 conserved hypothetical protein 8.21 1 2 2 6 9.853E7 8.55 8.21 2 3 286.39 8.21 2 3 390 43.0 4.44 HVO_B0101 IclR family transcription regulator 8.17 1 2 2 3 2.252E7 517.39 8.17 2 3 257 28.6 5.02 HVO_0853 DNA double-strand break repair protein Mre11 8.16 1 3 3 8 1.200E8 4.56 4.76 2 3 292.34 8.16 3 5 441 48.1 4.39 HVO_1668 gamma-glutamylcysteine synthetase 8.10 1 3 3 9 1.747E7 0.00 8.10 3 5 290.81 5.03 2 4 358 39.9 4.72 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 8.07 1 0 4 17 2.596E8 18.54 8.07 3 8 1391.93 8.07 4 9 384 42.4 5.40 HVO_0194 Orc1-type DNA replication protein 8.02 1 4 4 10 3.317E7 0.00 6.15 3 4 282.20 8.02 4 6 374 42.2 4.94 HVO_0326 CTP-dependent riboflavin kinase 8.02 1 2 2 8 8.974E7 7.94 8.02 2 4 588.27 8.02 2 4 237 25.9 4.55 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 8.01 1 2 2 4 3.129E7 3.38 8.01 2 2 139.48 8.01 2 2 574 62.8 4.17 HVO_1117 HTH-10 family transcription regulator 7.98 1 2 2 8 2.669E7 6.45 7.98 2 4 496.28 7.98 2 4 213 23.3 4.56 HVO_2160 conserved hypothetical protein 7.93 1 12 12 58 6.494E8 55.92 7.93 12 29 4146.43 7.93 12 29 2257 232.7 3.92 HVO_1058 TrkA domain protein 7.87 1 3 3 12 5.686E7 4.14 7.87 3 6 435.05 7.87 3 6 445 47.7 4.35 HVO_2614 uridine phosphorylase 7.85 1 2 2 10 8.889E8 11.96 7.85 2 5 750.31 7.85 2 5 242 25.8 4.30 HVO_0968 NADH dehydrogenase-like complex subunit CD 7.80 1 0 4 15 2.791E8 10.97 7.80 4 7 849.24 7.80 4 8 564 63.3 4.60 HVO_0558 SAMP-activating enzyme E1 7.78 1 2 2 5 3.481E7 0.00 7.78 2 2 138.79 7.78 2 3 270 28.7 4.35 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 7.66 1 3 3 12 3.478E7 6.27 7.66 3 6 718.75 7.66 3 6 444 47.1 4.77 HVO_0220 ATP-dependent DNA helicase MCM 7.55 1 5 5 16 2.846E7 9.99 7.55 5 8 775.03 7.55 5 8 702 78.8 4.73 HVO_A0257 Orc1-type DNA replication protein 7.53 1 3 3 8 1.477E7 5.30 7.53 3 4 425.89 7.53 3 4 425 48.0 4.94 HVO_0328 NAD-dependent epimerase/dehydratase 7.43 1 2 2 4 2.066E7 0.00 7.43 2 2 133.00 7.43 2 2 296 31.7 5.07 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 7.40 1 2 2 6 9.901E6 2.73 7.40 2 3 255.13 7.40 2 3 446 47.9 4.39 HVO_0475 conserved hypothetical protein 7.37 1 2 2 4 9.902E6 0.00 7.37 2 2 128.09 7.37 2 2 312 32.5 4.74 HVO_0470 threonine synthase 7.36 1 2 2 4 3.094E7 0.00 7.36 2 2 99.20 7.36 2 2 367 39.2 4.59 HVO_1594 tRNA/rRNA cytosine-C5-methylase 7.35 1 2 2 8 8.851E7 6.20 7.35 2 4 442.11 7.35 2 4 313 34.6 4.69 HVO_A0331 D-galactonate dehydratase 7.29 1 2 2 6 9.852E7 7.41 7.29 2 3 228.29 7.29 2 3 384 42.8 4.83 HVO_1864 molybdopterin synthase catalytic subunit 7.28 1 2 2 5 6.465E7 1.71 7.28 2 2 175.55 7.28 2 3 261 27.9 4.41 21961227 Keratin 6B [Homo sapiens] 7.27 1 0 5 25 3.456E8 23.71 7.27 4 12 1770.51 7.27 5 13 564 60.0 8.00 HVO_1725 Orc1-type DNA replication protein 7.23 1 3 3 8 1.764E7 3.93 7.23 3 4 287.16 7.23 3 4 401 44.5 5.19 HVO_0322 MinD/ParA domain protein 7.23 1 3 3 12 1.268E8 9.97 7.23 3 6 702.30 7.23 3 6 581 58.8 3.70 HVO_1413 probable NADH dehydrogenase 7.16 1 2 2 6 4.294E7 4.85 7.16 2 3 338.88 7.16 2 3 377 39.7 4.67 HVO_1419 HTH-10 family transcription regulator 7.11 1 2 2 2 5.835E8 0.00 7.11 2 2 225 25.2 4.77 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 7.06 1 3 3 8 2.623E7 4.24 7.06 3 4 268.12 7.06 3 4 439 47.2 4.59 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 6.99 1 2 2 4 6.510E7 0.00 6.99 2 2 126.11 6.99 2 2 286 30.8 4.46 4557890 keratin 5 [Homo sapiens] 6.95 1 0 5 19 2.414E8 17.54 6.95 4 9 1310.35 6.95 5 10 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 6.95 1 0 5 19 2.414E8 17.54 6.95 4 9 1310.35 6.95 5 10 590 62.4 8.06 HVO_A0476 conserved hypothetical protein 6.95 1 2 2 2 3.484E7 98.98 6.95 2 2 331 35.4 4.26 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 10 6.152E8 4.27 5.40 2 4 734.02 6.94 3 6 389 40.8 4.89 HVO_B0183 YgeA family protein 6.94 1 2 2 3 3.715E7 194.07 6.94 2 3 245 26.8 4.58 HVO_1356 sensor box histidine kinase 6.91 1 2 2 6 5.504E7 2.71 6.91 2 2 244.08 6.91 2 4 550 61.1 4.60 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 6.84 1 2 2 4 2.489E7 372.01 6.84 2 4 395 42.4 4.54 HVO_2071 conserved hypothetical protein 6.74 1 3 3 11 1.069E8 15.50 6.74 3 6 814.70 6.74 3 5 549 58.4 4.72 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 6.69 1 2 2 8 3.177E8 9.74 6.69 2 4 584.81 6.69 2 4 299 32.0 4.53 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 6.67 1 2 2 2 1.558E7 2.24 6.67 2 2 345 37.0 3.95 HVO_2503 kynureninase 6.59 1 2 2 3 1.015E8 322.08 6.59 2 3 425 46.0 4.54 HVO_1228 halocyanin 6.46 1 4 4 18 7.614E7 20.29 6.46 4 9 1360.57 6.46 4 9 821 83.7 4.17 HVO_0464 threonine ammonia-lyase 6.45 1 2 2 2 1.997E7 127.95 6.45 2 2 403 43.7 4.72 HVO_0670 glutathione S-transferase 6.44 1 2 2 3 3.783E7 256.46 6.44 2 3 326 38.1 4.56 HVO_2479 2-phospho-L-lactate transferase 6.36 1 2 2 6 1.711E7 5.62 6.36 2 3 271.73 6.36 2 3 330 34.7 4.32 HVO_1895 KEOPS complex subunit Kae1/Bud32 6.34 1 2 2 8 5.604E7 13.16 6.34 2 4 597.01 6.34 2 4 552 59.0 5.07 HVO_1578 probable NADH dehydrogenase 6.30 1 2 2 8 2.164E8 5.03 6.30 2 4 431.16 6.30 2 4 397 42.8 4.40 HVO_A0047 UspA domain protein 6.23 1 2 2 6 1.535E7 3.41 6.23 2 3 210.81 6.23 2 3 289 30.8 4.53 HVO_2906 tRNA (cytidine/uridine-2'-O-)-methyltransferase 6.18 1 2 2 2 1.884E7 83.54 6.18 2 2 275 30.6 4.58 HVO_1374 acyl-CoA synthetase 6.15 1 3 3 9 2.376E7 5.69 4.34 2 4 622.35 6.15 3 5 553 61.1 4.50 HVO_0929 tRNA (guanine(37)-N(1))-methyltransferase 6.10 1 2 2 6 4.323E7 0.00 6.10 2 3 199.09 6.10 2 3 328 36.1 4.67 HVO_A0160 sensor box histidine kinase 6.07 1 2 2 2 7.511E7 0.00 6.07 2 2 708 76.5 4.79 HVO_C0044 PLD domain protein 6.01 1 2 2 8 4.062E7 0.00 6.01 2 4 232.55 6.01 2 4 333 36.4 4.94 HVO_2058 NAD-dependent epimerase/dehydratase (homolog to dTDP-4-dehydrorhamnose reductase) 6.00 1 2 2 6 2.721E8 2.06 6.00 2 3 202.73 6.00 2 3 300 32.0 4.22 HVO_B0127 oxidoreductase (luciferase family protein) 5.99 1 2 2 6 3.236E7 1.92 5.99 2 3 163.51 5.99 2 3 317 35.7 4.60 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 5.96 1 2 2 6 2.305E7 0.00 5.96 2 3 158.56 5.96 2 3 386 41.3 4.46 HVO_B0256 aldehyde ferredoxin oxidoreductase 5.95 1 2 2 4 2.535E7 0.00 5.95 2 2 124.48 5.95 2 2 555 59.9 4.55 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 5.95 1 2 2 3 7.923E7 218.21 5.95 2 3 353 36.7 4.65 HVO_2255 conserved hypothetical protein 5.93 1 2 2 3 3.419E7 179.35 5.93 2 3 236 27.7 5.60 HVO_2510 GNAT family acetyltransferase 5.92 1 2 2 6 5.727E7 0.00 5.92 2 3 185.48 5.92 2 3 304 33.7 4.49 HVO_0812 phosphoenolpyruvate synthase 5.78 1 4 4 12 6.063E7 7.51 5.78 4 6 732.98 5.78 4 6 761 83.1 4.63 HVO_A0180 SMC-like protein Sph1 5.73 1 2 2 6 2.872E7 2.17 5.73 2 3 213.33 5.73 2 3 593 66.4 4.58 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 5.69 1 2 2 8 2.398E7 5.26 5.69 2 4 244.05 5.69 2 4 492 52.1 4.83 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 5.59 1 2 2 3 2.377E8 201.26 5.59 2 3 376 41.8 4.91 HVO_A0156 acyl-CoA synthetase 5.57 1 0 3 14 1.086E8 10.58 5.57 3 7 780.45 5.57 3 7 664 74.0 4.40 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 5.50 1 0 4 17 2.596E8 18.54 5.50 3 8 1391.93 5.50 4 9 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 5.50 1 0 4 17 2.596E8 18.54 5.50 3 8 1391.93 5.50 4 9 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 5.50 1 0 4 17 2.596E8 18.54 5.50 3 8 1391.93 5.50 4 9 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 5.50 1 0 4 17 2.596E8 18.54 5.50 3 8 1391.93 5.50 4 9 564 60.0 7.72 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 5.41 1 2 2 3 3.176E7 211.18 5.41 2 3 740 85.6 4.70 HVO_2888 homolog to elongator complex protein ELP3 5.09 1 3 3 7 6.261E7 3.83 5.09 3 3 268.12 5.09 3 4 550 62.6 5.01 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 5.08 1 0 3 9 2.177E8 0.00 5.08 3 5 377.55 3.39 2 4 472 51.6 5.16 HVO_2350 YyaL family protein 5.07 1 2 2 6 1.141E8 4.51 5.07 2 3 374.09 5.07 2 3 552 58.8 4.59 HVO_B0076 N-methylhydantoinase (ATP-hydrolyzing) A 5.06 1 2 2 6 2.636E7 4.33 5.06 2 3 262.38 5.06 2 3 514 54.0 4.30 HVO_0689 chromosome segregation protein Smc 5.00 1 4 4 9 9.251E7 4.55 3.15 3 4 228.12 5.00 4 5 1240 138.1 4.39 HVO_2158 malic enzyme (NADP) 4.93 1 0 3 19 1.003E8 13.89 4.93 3 9 948.86 4.93 3 10 751 81.4 4.55 HVO_B0001 Orc1-type DNA replication protein 4.88 1 3 3 7 1.965E7 4.46 4.88 2 3 301.82 4.88 3 4 410 45.8 5.33 HVO_1340 "probable glycosyltransferase, type 1" 4.80 1 2 2 6 9.519E7 1.70 4.80 2 3 173.18 4.80 2 3 375 41.0 4.42 HVO_2880 probable peptide chain release factor pelota 4.78 1 2 2 6 1.616E8 5.01 4.78 2 3 359.20 4.78 2 3 356 39.3 4.63 HVO_2095 probable oxidoreductase (zinc-containing alcohol dehydrogenase family) 4.75 1 2 2 3 2.653E7 2.33 4.75 2 3 337 35.9 4.39 HVO_A0551 acyl-CoA synthetase 4.65 1 2 2 6 1.759E7 5.35 4.65 2 3 401.06 4.65 2 3 538 59.6 4.65 HVO_1357 receiver/bat box HTH-10 family transcription regulator 4.64 1 2 2 4 2.453E7 3.93 4.64 2 2 176.69 4.64 2 2 582 62.7 4.40 HVO_B0038A D-xylonate dehydratase 4.61 1 0 2 8 3.669E8 4.21 4.61 2 4 388.23 4.61 2 4 412 45.5 4.55 HVO_C0042 helicase domain protein 4.55 1 5 5 14 5.615E7 3.87 4.55 5 7 454.88 4.55 5 7 1274 144.4 4.67 HVO_0768 radical SAM domain protein 4.42 1 2 2 3 3.477E7 204.84 4.42 2 3 565 62.0 4.84 HVO_1565 DNA ligase (ATP) 4.27 1 2 2 6 1.200E7 6.83 4.27 2 3 436.43 4.27 2 3 585 62.7 4.44 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 4.15 1 2 2 2 4.950E7 90.93 4.15 2 2 482 50.6 4.31 HVO_2369 conserved hypothetical protein 4.01 1 2 2 2 4.699E6 1.65 4.01 2 2 424 47.3 5.06 HVO_0817 phytoene dehydrogenase (phytoene desaturase) 4.00 1 2 2 3 3.452E7 171.05 4.00 2 3 425 46.1 4.98 HVO_A0326 beta-D-galactosidase 3.95 1 2 2 2 1.830E8 85.57 3.95 2 2 684 76.7 4.69 HVO_B0054 sirohydrochlorin cobaltochelatase 3.94 1 2 2 7 3.389E7 1.69 3.94 2 3 317.73 3.94 2 4 406 44.1 4.72 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 3.94 1 2 2 3 5.637E7 161.29 3.94 2 3 584 63.3 4.79 31074633 keratin 6L [Homo sapiens] 3.93 1 0 2 6 1.542E8 5.94 3.93 2 3 568.65 3.93 2 3 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 3.93 1 0 2 6 1.542E8 5.94 3.93 2 3 568.65 3.93 2 3 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 3.93 1 0 2 6 1.542E8 5.94 3.93 2 3 568.65 3.93 2 3 535 57.7 7.20 HVO_B0154 receiver/sensor box histidine kinase 3.92 1 5 5 14 3.375E7 6.24 3.23 4 6 612.92 3.07 4 8 1301 144.1 4.39 HVO_1380 methylmalonyl-CoA mutase subunit A 3.76 1 2 2 8 3.513E7 1.77 3.76 2 4 171.17 3.76 2 4 558 61.9 4.41 386849 keratin type II 3.73 1 0 2 8 1.734E8 10.80 3.73 2 4 881.37 3.73 2 4 563 59.9 7.94 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 3.66 1 2 2 6 4.859E7 3.46 3.66 2 3 237.38 3.66 2 3 573 62.9 4.45 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 3.47 1 0 2 3 2.930E8 0.00 3.47 2 3 432 48.1 5.02 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 3.46 1 2 2 9 5.004E7 7.04 3.46 2 4 668.09 3.46 2 5 838 89.1 4.65 31074631 keratin 1b [Homo sapiens] 3.46 1 0 2 3 3.643E8 480.87 3.46 2 3 578 61.8 5.97 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 8 3.230E8 0.00 3.45 2 4 377.55 3.45 2 4 464 50.6 5.47 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 3.38 1 0 2 8 3.230E8 0.00 3.38 2 4 377.55 3.38 2 4 473 51.2 5.05 HVO_C0043 conserved hypothetical protein 3.33 1 2 2 6 4.317E7 6.34 3.33 2 3 242.40 3.33 2 3 661 73.8 4.75 HVO_0311 A-type ATP synthase subunit I 3.27 1 2 2 6 7.220E7 4.18 3.27 2 3 308.14 3.27 2 3 733 79.5 4.41 HVO_B0044 siderophore biosynthesis protein IucA 2.36 1 2 2 6 1.338E7 0.00 2.36 2 3 188.99 2.36 2 3 593 65.8 4.59 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 2.17 1 3 3 5 3.145E7 1.76 1.35 2 2 149.09 2.17 3 3 1335 150.5 4.60 4504919 keratin 8 [Homo sapiens] 2.07 1 0 2 5 4.320E8 510.56 2.07 2 5 483 53.7 5.59 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 1.98 1 2 2 6 2.345E7 3.73 1.98 2 3 276.67 1.98 2 3 858 93.9 4.69 HVO_A0550 receiver/sensor box histidine kinase 1.69 1 2 2 8 1.791E7 5.67 1.69 2 4 473.02 1.69 2 4 885 95.9 4.46