Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0359 translation elongation factor aEF-1 alpha subunit 79.33 1 19 23 940 7.081E10 911.86 75.06 22 434 72019.50 79.33 23 506 421 45.7 4.73 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 72.68 1 15 15 159 8.239E9 143.09 72.68 15 79 10901.97 72.68 15 80 355 38.2 4.68 HVO_0356 translation elongation factor aEF-2 70.15 1 39 39 770 2.402E10 717.60 70.15 38 382 44962.95 70.15 39 388 727 80.4 4.73 HVO_0536 ferritin 67.61 1 6 6 29 8.385E8 24.20 67.61 6 14 1432.88 67.61 6 15 176 19.9 4.50 HVO_2862 serine hydroxymethyltransferase 67.23 1 17 17 258 6.771E9 202.34 67.23 17 133 14872.47 67.23 17 125 415 44.3 4.53 HVO_0212 homolog to lactoylglutathione lyase 65.32 1 4 4 13 6.785E8 10.60 43.55 3 6 731.92 65.32 4 7 124 13.5 4.13 HVO_2900 fumarate hydratase 65.03 1 19 19 142 7.101E9 126.25 65.03 19 70 7811.07 65.03 19 72 469 50.1 4.78 HVO_0329 branched-chain amino acid aminotransferase 64.10 1 16 16 139 4.321E9 135.60 64.10 16 68 8892.09 64.10 16 71 312 35.0 4.58 HVO_0677 aspartate--tRNA ligase 63.36 1 19 19 248 9.513E9 232.35 61.75 18 124 14542.04 62.21 18 124 434 48.7 4.50 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 62.86 1 14 14 181 6.527E9 131.76 62.86 14 90 10548.43 62.86 14 91 350 37.6 4.54 HVO_2783 30S ribosomal protein S4 62.86 1 11 12 62 2.919E9 41.52 62.86 12 33 3645.74 59.43 10 29 175 20.1 5.24 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 61.94 1 15 15 181 1.275E10 142.86 61.94 15 88 10570.56 61.94 15 93 381 41.0 4.23 HVO_1921 serine--tRNA ligase 61.74 1 22 22 120 2.129E9 102.41 53.70 21 59 7281.51 61.74 22 61 460 52.0 4.46 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 61.34 1 6 6 48 2.583E9 36.97 50.52 5 20 3211.31 61.34 6 28 194 20.7 4.12 HVO_2913 superoxide dismutase (Mn) 60.80 1 0 6 92 1.020E10 85.90 60.80 6 45 5547.09 60.80 6 47 199 22.3 4.48 HVO_A0475 superoxide dismutase (Mn) 60.50 1 0 6 92 1.020E10 85.90 60.50 6 45 5547.09 60.50 6 47 200 22.4 4.45 HVO_0025 thiosulfate sulfurtransferase 59.44 1 10 10 239 1.467E10 209.49 59.44 10 116 13861.08 59.44 10 123 286 32.1 4.28 HVO_0880 conserved hypothetical protein 59.28 1 17 17 114 1.180E9 117.57 59.28 17 58 7266.53 57.33 15 56 307 36.3 4.74 HVO_2588 isocitrate dehydrogenase (NADP) 58.95 1 20 20 190 8.276E9 192.93 55.85 19 95 12690.85 58.95 19 95 419 45.8 4.59 HVO_0175 DNA polymerase sliding clamp 58.70 1 8 8 140 5.874E9 108.26 44.53 7 66 7696.27 58.70 8 74 247 26.7 4.39 HVO_1082 homolog to orotate phosphoribosyltransferase 58.10 1 9 9 43 1.618E9 32.41 45.24 7 21 2268.30 52.86 8 22 210 22.3 4.42 HVO_1637 FKBP-type peptidylprolyl isomerase 57.52 1 9 10 74 4.624E9 54.70 34.31 8 34 4334.17 55.88 9 40 306 33.8 3.76 HVO_1273 inosine-5'-monophosphate dehydrogenase 57.43 1 17 17 134 2.320E9 91.54 54.82 16 66 7392.10 57.43 17 68 498 53.3 4.55 HVO_2015 conserved hypothetical protein 57.39 1 13 13 219 2.424E10 219.07 57.39 13 106 15587.71 57.39 13 113 345 37.7 4.25 HVO_2413 translation elongation factor aEF-1 alpha subunit 56.90 1 13 17 195 1.318E10 131.46 52.62 16 94 10467.66 56.90 17 101 420 45.6 4.75 HVO_1133 conserved hypothetical protein 55.45 1 4 4 21 6.375E8 19.35 55.45 4 10 1418.11 55.45 4 11 101 11.7 4.58 HVO_2968 phosphoglycerate dehydrogenase 55.05 1 19 19 221 8.289E9 212.11 48.19 17 107 15415.71 55.05 19 114 525 55.3 4.36 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 54.80 1 12 12 67 2.418E9 59.88 54.80 12 32 4131.34 54.80 12 35 281 30.6 4.59 HVO_0240 Lrp/AsnC family transcription regulator 54.61 1 7 8 45 3.395E9 31.53 49.34 7 22 2844.33 54.61 8 23 152 16.9 4.39 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 54.48 1 5 5 21 5.762E8 18.19 47.76 4 10 1513.65 38.06 4 11 134 13.9 4.55 HVO_0859 FeS assembly ATPase SufC 54.15 1 14 14 100 3.267E9 72.03 40.86 12 47 6293.23 54.15 14 53 301 33.4 4.35 HVO_0104 DNA repair and recombination protein RadA 53.94 1 13 13 83 2.640E9 55.18 46.94 11 36 5175.19 51.90 12 47 343 37.3 4.64 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 53.91 1 15 15 155 7.110E9 164.43 53.91 15 79 11425.07 53.91 15 76 384 41.4 4.41 HVO_2487 aspartate-semialdehyde dehydrogenase 53.49 1 10 10 95 5.678E9 60.78 53.49 10 46 4047.95 51.16 9 49 344 36.6 4.41 HVO_0133 thermosome subunit 1 53.39 1 19 21 151 4.154E9 141.92 53.39 21 75 9696.56 52.14 19 76 560 58.9 4.25 HVO_0161 ATP phosphoribosyltransferase 53.02 1 12 12 51 1.162E9 44.90 53.02 12 24 3130.45 53.02 12 27 281 30.4 4.60 HVO_0433 F420H2:NADP oxidoreductase 52.70 1 8 8 48 2.211E9 50.32 52.70 8 24 2886.38 52.70 8 24 222 23.3 4.72 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 52.24 1 10 10 165 7.212E9 139.46 52.24 10 82 9446.12 52.24 10 83 312 34.5 4.98 HVO_2519 conserved hypothetical protein 51.05 1 13 13 68 1.427E9 59.69 46.34 12 32 4527.38 51.05 13 36 382 40.7 4.35 HVO_0778 thermosome subunit 3 50.95 1 17 19 120 1.606E9 125.01 50.95 19 60 7879.42 50.95 19 60 524 55.2 4.59 HVO_0347 DNA-directed RNA polymerase subunit B'' 50.86 1 22 22 124 1.505E9 82.34 50.86 22 61 6741.74 50.86 22 63 521 58.9 5.00 HVO_2724 beta-lactamase domain protein 50.67 1 15 15 128 4.143E9 81.88 50.67 15 64 5731.85 50.67 15 64 450 50.1 5.40 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 34 2.547E9 13.10 37.91 4 15 1644.49 50.33 5 19 153 16.9 4.21 HVO_2969 threonine synthase 49.64 1 15 15 92 3.469E9 72.87 43.91 14 46 5284.67 49.64 15 46 419 44.4 4.49 HVO_2544 30S ribosomal protein S5 49.53 1 9 9 71 6.925E9 31.50 49.53 9 35 3320.78 49.53 9 36 214 23.3 9.29 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 49.46 1 7 7 44 1.617E9 38.91 44.02 6 20 3102.68 49.46 7 24 184 19.8 5.30 HVO_0239 glutamine synthetase 49.12 1 17 17 139 7.184E9 111.26 49.12 16 68 8126.96 49.12 17 71 456 50.5 4.56 HVO_2889 RecJ domain protein 49.11 1 24 24 151 4.879E9 111.28 45.13 23 74 8554.45 49.11 24 77 729 79.1 4.37 HVO_0876 methylglyoxal synthase 48.82 1 4 4 9 1.895E8 1.67 29.13 3 4 334.36 48.82 4 5 127 13.9 4.48 HVO_1145 30S ribosomal protein S1e 48.64 1 9 9 47 1.186E9 44.04 45.45 8 22 2743.54 48.64 9 25 220 24.8 4.86 HVO_1955 aconitate hydratase 48.47 1 23 23 350 1.084E10 357.01 48.47 23 172 22912.72 48.47 23 178 654 70.4 4.45 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 48.43 1 10 10 133 6.387E9 143.21 48.43 10 67 9998.30 46.34 9 66 287 31.0 4.73 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 48.31 1 17 17 101 4.022E9 107.82 48.31 17 50 6453.42 48.31 17 51 592 66.6 4.61 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 47.95 1 23 23 308 9.702E9 247.65 47.95 23 149 19257.60 47.95 23 159 586 64.0 4.49 HVO_0455 thermosome subunit 2 47.58 1 18 20 157 4.411E9 106.99 43.99 19 73 8551.65 47.58 20 84 557 59.3 4.37 HVO_1973 conserved hypothetical protein 47.31 1 5 5 15 9.381E7 10.78 47.31 5 8 724.86 47.31 5 7 167 18.1 4.36 HVO_0055 CBS domain protein 47.18 1 10 10 66 1.987E9 64.66 47.18 10 33 4652.15 47.18 10 33 284 30.8 4.27 HVO_1132 adenylosuccinate synthase 47.18 1 21 21 214 5.792E9 157.75 44.02 20 103 12051.39 47.18 21 111 443 48.2 4.56 HVO_0937 FMN-binding domain protein 46.58 1 4 4 12 2.871E8 7.21 35.62 3 5 576.17 46.58 4 7 146 16.2 4.36 HVO_0999 DRTGG domain protein 46.56 1 12 12 66 1.252E9 55.06 46.56 12 34 3434.18 46.56 12 32 378 39.8 4.44 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 137 4.215E9 138.93 43.25 7 66 9866.04 46.37 8 71 289 29.8 4.27 HVO_0317 A-type ATP synthase subunit B 45.94 1 13 14 104 5.794E9 124.67 45.94 14 51 8116.20 45.94 14 53 468 51.9 4.25 HVO_0024 thiosulfate sulfurtransferase 45.74 1 8 8 50 1.221E9 28.21 34.50 6 22 2230.75 45.74 8 28 258 28.4 4.30 HVO_1332 conserved hypothetical protein 45.74 1 5 5 24 6.124E8 11.13 45.74 5 12 1350.89 45.74 5 12 129 14.9 4.16 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 45.64 1 20 20 305 1.285E10 325.73 43.42 18 148 21766.94 45.64 20 157 631 68.4 4.49 HVO_1300 triosephosphate isomerase 45.33 1 6 6 32 2.842E9 27.70 45.33 6 16 2135.25 45.33 6 16 214 21.3 4.26 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 45.22 1 15 15 65 1.270E9 50.17 43.95 14 30 3328.62 45.22 15 35 471 51.0 4.48 HVO_2384 CBS domain protein 45.00 1 13 13 129 5.218E9 75.11 45.00 13 64 6161.34 45.00 13 65 380 42.5 5.01 HVO_0348 DNA-directed RNA polymerase subunit B' 44.66 1 22 22 116 1.573E9 94.95 44.66 22 59 6342.99 43.84 21 57 609 67.7 4.92 HVO_0792 3-dehydroquinate synthase type II 44.64 1 13 13 50 1.152E9 35.83 37.50 12 25 2266.47 44.64 12 25 392 43.1 4.44 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 44.59 1 12 12 74 3.165E9 64.49 38.36 10 33 5056.11 44.59 12 41 305 33.8 4.74 HVO_0314 A-type ATP synthase subunit C 44.25 1 12 12 48 6.901E8 26.06 37.07 10 24 2638.86 41.95 11 24 348 38.7 4.50 HVO_1541 glycerol kinase 44.12 1 17 17 97 3.106E9 52.85 40.78 16 46 5934.29 42.55 16 51 510 56.7 4.50 HVO_0889 FAD-dependent oxidoreductase 43.93 1 4 4 10 1.724E8 5.90 24.77 3 4 630.51 43.93 4 6 214 21.8 3.89 HVO_2204 "FtsZ family protein, type III" 43.80 1 12 14 67 2.761E9 63.40 43.80 14 34 4575.55 41.77 13 33 395 42.0 4.68 HVO_0400 conserved hypothetical protein 43.65 1 4 4 9 2.358E8 1.62 38.89 3 4 312.87 43.65 4 5 126 13.9 4.68 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 43.61 1 10 10 51 1.572E9 34.03 43.61 10 22 2632.88 43.61 10 29 360 39.6 4.39 HVO_1507 acetolactate synthase small subunit 43.58 1 7 7 23 3.918E8 10.82 43.58 7 12 1035.36 43.58 7 11 218 23.7 4.94 HVO_0401 UspA domain protein 43.42 1 5 5 27 1.611E9 27.35 32.89 4 13 1729.48 43.42 5 14 152 16.4 4.79 HVO_0806 pyruvate kinase 43.25 1 17 18 77 2.761E9 55.51 41.20 17 37 4262.00 42.22 17 40 585 62.0 4.54 HVO_0869 glutamate synthase large subunit 43.22 1 47 48 239 2.654E9 212.92 42.49 46 117 14989.57 43.22 47 122 1511 163.8 4.70 HVO_0860 SufB domain protein 42.65 1 15 15 117 2.978E9 90.88 39.50 14 57 7036.80 41.18 14 60 476 53.2 4.69 HVO_2013 "FtsZ family protein, type III" 42.64 1 8 8 50 8.360E8 49.18 42.64 8 23 3658.07 42.64 8 27 394 41.5 4.61 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 42.50 1 9 9 53 2.354E9 38.94 42.50 9 27 2855.75 42.50 9 26 280 30.1 4.44 HVO_1684 threonine--tRNA ligase 42.46 1 24 24 141 3.371E9 111.31 42.46 24 68 7717.46 42.46 24 73 643 73.4 4.45 HVO_2558 30S ribosomal protein S3 42.43 1 10 10 158 5.026E9 145.55 38.16 9 77 10647.39 42.43 10 81 304 33.4 4.06 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.11 1 9 9 47 1.174E9 33.46 42.11 9 23 2570.82 42.11 9 24 266 27.8 4.84 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 42.08 1 8 8 49 1.472E9 47.80 42.08 8 24 3499.92 42.08 8 25 259 28.0 4.50 HVO_2981 uracil phosphoribosyltransferase 42.04 1 7 7 27 2.230E9 18.62 39.82 6 11 1280.20 42.04 7 16 226 24.5 4.49 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 41.76 1 12 12 52 7.442E8 33.92 40.00 11 26 2802.01 41.76 11 26 340 38.8 4.58 HVO_0316 A-type ATP synthase subunit A 41.64 1 18 18 119 3.762E9 112.71 40.44 17 57 7049.66 41.64 18 62 586 64.5 4.25 HVO_2225 AstE family protein 41.64 1 8 8 29 1.288E9 21.91 41.64 8 14 1499.71 33.72 7 15 341 36.9 4.53 HVO_2040 NAD-dependent epimerase/dehydratase 41.50 1 6 10 59 2.200E9 50.77 41.50 10 29 3984.16 41.50 10 30 306 33.8 4.51 HVO_1506 ketol-acid reductoisomerase 41.38 1 8 8 30 4.981E8 23.56 41.38 8 15 1755.34 41.38 8 15 348 37.9 4.34 HVO_1187 conserved hypothetical protein 41.26 1 5 5 22 2.223E8 11.17 41.26 5 11 939.13 41.26 5 11 143 16.4 4.86 HVO_1481 UspA domain protein 41.10 1 5 5 49 3.516E9 47.33 41.10 5 23 3076.59 41.10 5 26 163 17.7 4.40 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 40.91 1 8 8 25 9.531E8 23.69 34.97 7 12 1868.33 40.91 8 13 286 31.2 4.54 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 40.91 1 9 9 43 1.003E9 45.02 40.91 9 22 2786.33 40.91 9 21 330 36.3 4.35 HVO_2552 30S ribosomal protein S4e 40.89 1 7 7 86 1.091E10 78.91 38.06 6 42 5301.04 40.89 7 44 247 26.6 4.58 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 40.52 1 10 10 39 9.802E8 37.35 40.52 10 20 2505.24 40.52 10 19 343 38.4 4.94 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 75 2.928E9 74.87 40.26 5 41 5503.81 40.26 5 34 154 17.5 4.50 HVO_1212 KaiC-type circadian regulator CirA 40.24 1 9 9 64 2.778E9 66.78 40.24 9 32 4845.24 40.24 9 32 246 27.5 4.45 HVO_0357 ACT domain protein 40.21 1 5 5 21 8.530E8 18.23 40.21 5 11 984.73 40.21 5 10 189 20.2 4.59 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 40.04 1 11 11 61 1.213E9 40.89 40.04 11 28 3315.48 40.04 11 33 457 48.4 4.35 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 26 8.997E8 18.89 40.00 4 12 997.38 40.00 4 14 130 14.1 4.79 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 39.78 1 10 10 47 1.268E9 49.75 39.78 10 25 2659.05 39.78 10 22 445 47.8 4.86 HVO_1545 dihydroxyacetone kinase subunit DhaL 39.66 1 7 7 65 3.102E9 58.56 39.66 7 32 3908.21 39.66 7 33 232 24.8 4.48 HVO_1198 UspA domain protein 39.31 1 5 5 20 1.207E9 19.89 39.31 5 10 1291.94 39.31 5 10 145 15.6 4.75 HVO_0203 replication factor C small subunit 39.14 1 9 9 44 5.106E8 19.07 39.14 9 21 1657.04 39.14 9 23 327 36.2 4.51 HVO_2419 hydroxymethylglutaryl-CoA synthase 39.10 1 13 13 60 1.525E9 39.26 39.10 13 30 2345.17 39.10 13 30 445 50.1 4.64 HVO_0870 proline--tRNA ligase 38.93 1 14 15 64 1.982E9 42.81 33.40 12 30 4056.63 35.04 13 34 488 54.9 4.44 HVO_2191 formyltetrahydrofolate deformylase 38.84 1 9 9 34 1.566E9 24.96 38.84 9 17 1942.95 35.47 8 17 327 36.2 4.63 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 38.46 1 16 16 102 1.924E9 66.50 37.18 15 49 5483.22 33.97 15 53 624 67.6 4.27 HVO_2774 enolase 38.35 1 8 8 53 2.448E9 43.51 32.83 7 25 3046.90 38.35 8 28 399 42.0 4.37 HVO_1502 3-isopropylmalate dehydrogenase 38.27 1 10 10 65 2.719E9 67.40 30.56 9 30 5112.42 38.27 10 35 324 33.7 4.23 HVO_2646 dihydroxy-acid dehydratase 38.18 1 15 15 118 3.313E9 113.79 38.18 15 56 7154.72 38.18 15 62 584 61.8 4.42 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 38.05 1 7 7 43 1.013E9 30.62 38.05 7 22 1856.52 25.59 6 21 297 31.3 4.36 HVO_0729 inorganic pyrophosphatase 37.85 1 7 7 48 2.221E9 50.70 37.85 7 24 3259.30 37.85 7 24 177 20.4 4.16 HVO_1391 NUDIX family hydrolase 37.75 1 5 5 24 2.205E8 23.91 37.75 5 12 1479.88 37.75 5 12 151 17.4 5.01 HVO_A0207 CRISPR-associated protein Cas7 37.65 1 9 9 54 1.591E9 46.02 34.71 8 26 3313.36 37.65 9 28 340 38.2 4.54 HVO_1854 histidine--tRNA ligase 37.59 1 12 12 48 1.011E9 30.65 35.50 11 23 2403.82 37.59 12 25 431 47.1 4.37 HVO_B0118 SMC-like protein Sph2 37.58 1 18 18 96 1.984E9 68.11 37.58 18 45 4908.44 37.58 18 51 644 73.8 4.41 HVO_0717 "cell division protein FtsZ, type I" 37.47 1 11 11 84 3.438E9 87.33 34.56 10 41 5979.99 37.47 11 43 379 39.8 4.40 HVO_1901 translation initiation factor aIF-2 gamma subunit 37.47 1 11 11 56 2.084E9 33.12 37.47 11 27 2814.76 37.47 11 29 411 43.9 4.36 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 37.37 1 5 5 29 1.317E9 20.52 37.37 5 15 1080.77 37.37 5 14 190 20.6 4.30 HVO_2643 NADPH:quinone reductase 37.28 1 10 10 36 2.181E8 33.63 37.28 10 18 2311.60 37.28 9 18 346 37.2 4.55 HVO_2347 conserved hypothetical protein 37.14 1 5 5 15 2.427E8 12.67 37.14 5 8 785.05 37.14 5 7 140 15.5 4.37 HVO_2777 30S ribosomal protein S9 37.12 1 5 5 12 1.253E8 8.98 37.12 5 6 448.00 37.12 5 6 132 14.7 9.74 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 37.05 1 8 8 70 5.628E9 50.81 37.05 8 35 4198.19 37.05 8 35 413 45.8 4.45 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 37.01 1 10 10 58 2.874E9 62.08 37.01 10 30 3677.89 29.20 9 28 435 46.9 4.63 HVO_0894 acyl-CoA synthetase 37.01 1 8 17 113 2.223E9 79.36 35.50 16 55 6059.44 37.01 17 58 662 74.3 4.48 HVO_2675 histidinol dehydrogenase 36.68 1 8 8 43 3.456E8 45.11 34.35 7 21 2475.36 36.68 8 22 428 45.4 4.50 HVO_A0206 CRISPR-associated protein Cas8b 36.54 1 19 19 80 1.523E9 53.78 35.70 18 39 3849.33 36.54 19 41 717 79.3 4.60 HVO_1091 proteasome alpha subunit 36.51 1 7 9 39 1.458E9 25.92 36.51 9 19 2608.28 33.33 8 20 252 27.6 4.56 HVO_1172 NAD-dependent epimerase/dehydratase 36.51 1 8 8 45 2.051E9 31.13 33.97 7 21 2236.72 36.51 8 24 315 34.9 4.34 HVO_3007 malate dehydrogenase 36.51 1 12 12 205 7.835E9 183.24 36.51 11 103 10483.39 36.51 11 102 304 32.6 4.40 HVO_0167 adenosylhomocysteinase 36.45 1 11 11 35 9.981E8 25.04 26.64 8 14 2546.44 36.45 11 21 428 46.6 4.39 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 36.43 1 8 8 60 1.537E9 69.19 33.87 7 27 4680.51 36.43 8 33 431 46.1 4.48 HVO_0861 SufB domain protein 36.32 1 11 11 87 3.261E9 77.63 36.32 11 42 5572.85 36.32 11 45 402 44.7 4.23 HVO_2773 30S ribosomal protein S2 36.15 1 5 5 45 3.521E9 42.82 36.15 5 22 3272.60 36.15 5 23 260 28.3 4.16 HVO_1459 ThuA family protein 36.13 1 5 5 27 1.076E9 28.16 36.13 5 14 1875.72 33.19 4 13 238 26.8 4.67 HVO_2706 translation initiation factor aIF-2B delta subunit 35.82 1 7 7 29 8.618E8 24.22 29.79 5 13 1320.48 35.82 7 16 282 30.7 4.42 HVO_1291 fumarylacetoacetase family protein 35.80 1 4 4 24 1.519E9 11.35 35.80 4 12 1225.80 35.80 4 12 243 26.3 4.55 HVO_0989 conserved hypothetical protein 35.71 1 4 4 18 3.846E8 15.18 35.71 4 9 1349.13 35.71 4 9 126 14.4 4.81 HVO_A0205 CRISPR-associated endoribonuclease Cas6 35.66 1 9 9 61 1.040E9 54.02 35.66 9 30 3985.05 35.66 9 31 272 31.0 5.44 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 35.57 1 6 6 17 1.134E9 17.28 35.57 6 8 1013.33 35.57 6 9 253 26.0 4.60 HVO_1546 dihydroxyacetone kinase subunit DhaK 35.54 1 11 11 113 3.085E9 68.78 35.54 11 58 5346.45 35.54 11 55 332 34.8 4.22 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 35.44 1 10 10 38 5.695E8 33.17 35.44 10 19 2342.00 35.44 10 19 364 39.3 4.35 HVO_2336 pyridoxal biosynthesis lyase PdxS 35.43 1 8 8 49 9.089E8 41.50 31.79 7 22 3356.52 35.43 8 27 302 32.5 4.81 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 35.30 1 13 13 42 1.329E9 24.03 35.30 13 22 1893.14 31.79 12 20 626 67.6 4.65 HVO_1504 3-isopropylmalate dehydratase large subunit 35.10 1 12 13 81 2.487E9 67.65 35.10 13 38 5113.39 35.10 13 43 473 51.6 4.55 HVO_1593 PAC2 family protein 35.08 1 4 4 19 6.621E8 15.69 35.08 4 9 784.79 35.08 4 10 248 26.6 4.46 HVO_2708 YfiH family protein 34.47 1 6 6 36 1.092E9 35.57 34.47 6 18 2134.44 34.47 6 18 322 35.4 4.35 HVO_2057 sugar nucleotidyltransferase 34.45 1 10 10 54 2.420E9 40.53 34.45 10 27 3061.67 34.45 10 27 357 37.8 4.44 HVO_2813 RimK family protein 34.44 1 12 12 64 2.653E9 53.21 32.89 11 31 3956.12 34.44 12 33 453 49.0 4.73 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 34.36 1 11 11 78 2.549E9 47.13 30.50 10 35 4595.50 34.36 11 43 259 29.9 4.36 HVO_B0059 cobalt-precorrin 5A hydrolase 34.36 1 7 7 26 3.293E8 19.90 34.36 7 13 1364.15 23.62 6 13 326 34.5 4.51 HVO_0449 prephenate dehydratase 34.33 1 7 7 34 5.441E8 27.69 34.33 7 17 2085.09 34.33 7 17 268 28.7 4.64 HVO_2059 NAD-dependent epimerase/dehydratase 34.19 1 7 7 43 1.397E9 33.82 34.19 7 20 2507.20 34.19 7 23 310 34.1 4.40 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 34.04 1 5 5 28 1.132E9 16.45 28.19 4 13 1497.61 34.04 5 15 188 20.5 4.60 HVO_0313 A-type ATP synthase subunit E 34.02 1 4 5 17 1.309E8 16.38 31.44 4 8 895.91 34.02 5 9 194 22.0 4.31 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 33.98 1 29 29 125 1.501E9 84.64 30.49 26 60 6520.94 33.98 29 65 1033 114.3 4.45 HVO_1590 DnaK-type molecular chaperone Hsp70 33.92 1 19 19 151 5.189E9 132.26 33.92 19 74 10015.46 33.92 19 77 625 67.2 4.18 HVO_A0156 acyl-CoA synthetase 33.89 1 6 15 89 2.223E9 56.89 33.89 15 42 4343.46 33.89 15 47 664 74.0 4.40 HVO_1454 aspartate carbamoyltransferase catalytic subunit 33.88 1 7 7 18 2.357E8 2.63 27.63 6 8 588.98 25.00 6 10 304 33.7 4.92 HVO_1387 enoyl-CoA hydratase 33.85 1 6 6 22 1.417E8 13.77 19.46 5 10 1067.72 33.85 6 12 257 27.5 4.51 HVO_0809 methionine--tRNA ligase 33.78 1 18 18 93 1.329E9 82.52 33.78 18 46 5672.43 33.78 18 47 740 81.9 4.37 HVO_1164 HD family hydrolase 33.70 1 8 8 31 5.949E8 9.64 33.70 8 17 1276.04 28.89 7 14 270 29.8 4.87 HVO_1896 30S ribosomal protein S24e 33.66 1 3 3 5 4.250E7 2.67 33.66 3 3 294.57 20.79 2 2 101 11.6 4.68 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 33.63 1 7 7 38 2.887E8 35.83 33.63 7 20 2471.31 33.63 7 18 336 36.8 4.12 HVO_1084 adenylosuccinate lyase 33.48 1 11 11 38 3.827E8 29.35 27.65 9 17 2055.09 33.48 11 21 463 50.8 4.70 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 33.39 1 15 15 46 8.506E8 51.79 33.39 15 23 3266.39 33.39 15 23 599 65.3 4.51 HVO_A0307 Lrp/AsnC family transcription regulator 33.33 1 5 5 18 1.586E8 8.34 33.33 5 9 736.59 33.33 5 9 177 19.4 4.39 HVO_1189 aldehyde dehydrogenase 33.27 1 12 12 61 2.687E9 44.99 29.53 11 29 3377.63 33.27 12 32 508 56.1 4.59 HVO_0829 peptidase S9 family protein 33.22 1 12 12 55 1.058E9 38.12 28.13 10 26 2930.96 33.22 12 29 608 67.4 4.54 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 33.19 1 8 8 40 1.444E9 39.40 33.19 8 19 2849.57 33.19 8 21 226 25.5 4.25 HVO_0350 DNA-directed RNA polymerase subunit A'' 33.17 1 11 11 46 2.210E9 37.82 33.17 11 23 2623.68 33.17 11 23 419 46.1 4.35 HVO_0480 phosphoglycerate kinase 32.92 1 10 10 44 1.475E9 42.77 32.92 10 22 2828.76 32.92 10 22 401 43.6 4.37 HVO_A0636 YbaK domain protein 32.91 1 3 3 12 1.157E8 14.34 32.91 3 6 613.74 32.91 3 6 158 16.7 4.54 HVO_1134 conserved hypothetical protein 32.89 1 16 16 82 7.425E8 47.37 32.89 16 40 3987.92 32.89 16 42 757 80.6 4.35 HVO_1575 arginase 32.78 1 5 5 17 2.712E8 8.84 32.78 5 8 336.27 32.78 5 9 299 31.0 4.58 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 32.67 1 5 5 20 2.397E8 12.04 32.67 5 10 911.67 32.67 5 10 202 22.2 5.11 HVO_0109 cysteine desulfurase 32.63 1 11 11 40 9.463E8 36.26 30.75 10 18 2862.95 32.63 11 22 426 46.8 4.56 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 32.46 1 15 15 60 1.342E9 39.58 31.25 14 29 2762.15 32.46 15 31 496 55.0 4.53 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 32.19 1 10 10 43 1.364E9 40.20 30.29 9 20 2418.05 32.19 10 23 525 56.4 4.40 HVO_2621 phosphoenolpyruvate carboxylase 32.11 1 22 22 107 2.331E9 84.30 27.54 20 51 5745.20 32.11 22 56 897 102.3 4.64 HVO_1123 thioredoxin-disulfide reductase 32.09 1 9 9 32 1.150E9 14.72 26.36 6 14 1765.09 32.09 9 18 349 37.3 4.32 HVO_2861 conserved hypothetical protein 32.00 1 8 8 46 1.249E9 47.30 32.00 8 23 2666.63 32.00 8 23 275 29.1 4.27 HVO_0388 homolog to ribonuclease R 31.89 1 12 12 54 4.772E8 47.88 31.89 12 28 3252.94 29.16 11 26 439 50.3 4.73 HVO_0353 30S ribosomal protein S12 31.69 1 7 7 31 8.651E8 34.20 31.69 7 18 1529.22 28.17 6 13 142 15.5 9.91 HVO_0549 2-keto-3-deoxygluconate kinase 31.56 1 9 9 31 4.747E8 20.34 25.31 7 16 1635.12 29.69 8 15 320 34.1 4.34 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 32 3.865E9 24.94 31.45 3 16 2128.24 31.45 3 16 124 14.2 5.22 HVO_B0382 TATA-binding transcription initiation factor 31.38 1 4 4 18 1.816E8 10.42 20.21 3 8 1028.98 31.38 4 10 188 20.1 4.12 HVO_0850 proteasome-activating nucleotidase 31.36 1 11 11 44 7.794E8 21.16 26.17 10 22 2009.31 31.36 11 22 405 45.6 4.60 HVO_0874 beta-lactamase domain protein 31.25 1 15 15 76 1.543E9 65.25 31.25 15 38 5523.07 27.03 14 38 640 71.9 5.14 HVO_0541 aconitate hydratase 31.24 1 16 17 46 1.468E9 25.57 29.32 15 22 1743.06 29.42 16 24 938 102.1 4.40 HVO_2624 CTP synthase 31.15 1 12 12 67 2.041E9 34.99 29.14 11 30 3517.29 31.15 12 37 549 60.8 4.70 HVO_1577 conserved hypothetical protein 31.07 1 5 5 17 7.488E8 13.45 25.99 4 8 864.14 31.07 5 9 177 19.4 4.74 HVO_0324 arginine--tRNA ligase 31.01 1 17 17 83 2.094E9 76.81 31.01 17 42 4949.58 29.98 15 41 587 65.0 4.35 HVO_2130 IclR family transcription regulator 30.88 1 7 7 17 2.739E8 4.00 26.84 6 8 889.29 30.88 7 9 272 30.1 5.55 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 30.85 1 8 8 34 2.599E8 27.86 28.65 7 16 1660.14 30.85 8 18 363 39.3 4.97 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 38 7.350E8 26.62 30.84 8 19 1665.50 30.84 8 19 415 44.4 4.41 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 30.65 1 8 8 31 5.581E8 18.80 30.65 8 16 1401.46 30.65 8 15 336 38.0 4.61 HVO_0046 putative glutamate--argW ligase 30.58 1 7 7 26 3.810E8 25.81 30.58 7 13 1625.05 30.58 7 13 291 31.9 4.87 HVO_2961 dihydrolipoyl dehydrogenase 30.53 1 10 10 28 3.587E8 25.91 25.05 9 13 1499.59 28.84 9 15 475 49.9 4.41 HVO_0743 probable phosphodiesterase 30.51 1 15 15 72 1.521E9 46.61 30.51 15 35 3639.96 28.73 14 37 449 50.5 4.56 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 30.47 1 4 4 13 1.066E8 6.96 21.09 3 6 807.49 30.47 4 7 128 13.0 4.31 HVO_1373 acyl-CoA dehydrogenase 30.29 1 7 7 30 5.306E8 16.75 30.29 7 14 1466.30 30.29 7 16 383 42.5 4.61 HVO_1287 PfpI family protease 29.80 1 5 5 18 6.265E8 8.54 23.23 3 8 578.81 29.80 5 10 198 21.5 4.53 HVO_1858 30S ribosomal protein S19e 29.80 1 2 2 4 1.046E8 237.11 29.80 2 4 151 16.7 4.84 HVO_0127 conserved hypothetical protein 29.71 1 2 2 2 0.000E0 1.75 29.71 2 2 138 15.5 4.63 HVO_0980 NADH dehydrogenase-like complex subunit CD 29.62 1 8 12 34 5.840E8 15.05 29.26 11 17 1327.57 29.62 12 17 557 63.4 4.53 HVO_1488 D-gluconate dehydratase 29.61 1 7 9 48 1.189E9 35.70 29.61 9 25 2345.35 29.61 9 23 412 45.8 4.60 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 29.60 1 9 9 36 2.225E8 21.91 25.58 8 16 1405.86 29.60 9 20 473 50.8 4.58 HVO_0292 replication protein A 29.58 1 7 7 27 3.681E8 19.95 24.44 6 12 1589.26 29.58 7 15 311 34.6 4.31 HVO_0601 homoserine dehydrogenase 29.43 1 6 6 21 4.739E8 20.82 17.72 4 9 1262.76 29.43 6 12 316 32.2 4.25 HVO_2436 malic enzyme (NADP) 29.43 1 13 16 61 6.553E8 46.77 29.43 16 31 3401.60 29.43 16 30 751 81.4 4.55 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 29.27 1 5 5 11 3.965E8 0.00 20.47 4 5 162.89 20.47 4 6 386 42.1 4.49 HVO_1727 TATA-binding transcription initiation factor 29.03 1 5 6 54 4.567E9 42.33 29.03 6 29 3453.60 29.03 6 25 186 19.9 4.36 HVO_2188 phosphoribosylformylglycinamidine synthase 1 29.02 1 5 5 14 8.910E8 9.05 25.89 4 7 755.16 24.11 4 7 224 23.9 4.36 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 28.97 1 6 6 22 1.631E9 26.50 28.97 6 12 1637.66 24.60 5 10 252 26.0 4.39 HVO_A0496 UspA domain protein 28.97 1 7 7 29 7.168E8 20.94 28.97 7 14 1467.13 28.97 7 15 290 31.4 4.60 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 28.89 1 5 5 33 2.392E8 23.00 28.89 5 16 1466.08 28.89 5 17 270 29.1 4.35 17318569 keratin 1 [Homo sapiens] 28.88 1 1 20 108 1.852E9 121.36 28.88 20 54 7630.07 28.88 20 54 644 66.0 8.12 HVO_1871 UPF0447 family protein 28.74 1 10 10 40 9.230E8 23.13 25.35 9 19 1715.98 20.16 8 21 501 56.1 4.59 HVO_2726 glutamate--tRNA ligase 28.72 1 13 13 52 8.774E8 35.76 25.13 11 25 2619.80 27.01 12 27 585 65.2 4.58 HVO_1878 NAD synthase 28.62 1 6 6 23 7.594E8 20.50 15.94 4 10 1259.85 28.62 6 13 276 29.6 4.37 HVO_0206 alanine--tRNA ligase 28.52 1 21 21 66 3.025E8 37.92 26.68 19 33 2996.64 28.52 21 33 922 102.4 4.54 HVO_0789 tryptophan synthase alpha subunit 28.52 1 5 5 17 3.220E8 11.71 28.52 5 8 668.48 28.52 5 9 277 29.6 4.21 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 28.48 1 8 8 23 8.602E8 17.51 23.00 7 11 931.99 24.47 7 12 474 53.4 4.59 HVO_1031 thioredoxin-disulfide reductase 28.36 1 6 6 25 6.109E8 26.23 28.36 6 12 1288.93 28.36 6 13 342 37.4 4.46 HVO_2912 ThiJ/PfpI domain protein 28.36 1 3 3 21 1.305E8 1.96 28.36 3 11 588.61 28.36 3 10 201 20.9 4.36 HVO_1572 DNA gyrase subunit B 28.17 1 16 16 45 3.313E8 24.01 24.10 13 21 1905.80 28.17 16 24 639 71.2 4.83 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 28.17 1 13 13 62 4.944E8 53.10 26.00 12 30 3572.96 26.67 12 32 600 65.3 4.68 HVO_0243 threonine aldolase 28.15 1 6 6 20 2.413E8 7.31 28.15 6 11 742.30 24.63 5 9 341 35.6 4.55 HVO_B0130 DUF296 family protein 28.15 1 3 3 8 1.737E8 1.93 28.15 3 4 336.13 28.15 3 4 135 14.8 4.41 HVO_1649 methionine adenosyltransferase 28.11 1 8 8 29 8.012E8 19.02 24.88 7 14 1236.09 28.11 8 15 402 43.5 4.45 HVO_1576 NAD-dependent epimerase/dehydratase 28.10 1 4 8 33 1.443E9 28.58 28.10 8 17 1808.40 25.49 7 16 306 33.9 4.51 HVO_0417 metal-dependent carboxypeptidase 28.09 1 13 13 48 7.229E8 36.60 28.09 13 24 2685.26 28.09 13 24 502 57.3 4.42 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 27.84 1 4 4 12 3.090E8 3.92 27.84 4 6 465.89 27.84 4 6 97 10.8 4.53 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 27.75 1 8 8 28 2.207E8 18.98 27.75 8 14 1265.30 27.75 8 14 454 48.5 4.46 HVO_1573 DNA gyrase subunit A 27.73 1 16 16 65 8.662E8 55.30 21.23 14 31 3807.70 24.71 15 34 862 94.8 4.56 HVO_0997 peptidase M24 family protein 27.72 1 5 5 12 1.085E8 2.21 27.72 5 6 410.19 20.92 4 6 368 39.9 4.49 HVO_1076 sugar nucleotidyltransferase 27.64 1 7 7 39 1.979E9 29.39 27.64 7 19 2370.45 27.64 7 20 322 35.8 4.20 HVO_A0388 Lrp/AsnC family transcription regulator 27.59 1 4 4 12 1.608E8 4.52 27.59 4 7 312.44 22.41 3 5 174 20.1 4.86 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 27.48 1 0 19 104 1.852E9 119.30 27.48 19 52 7391.65 27.48 19 52 644 66.0 8.12 HVO_2688 TrmB family transcription regulator 27.48 1 7 7 29 1.861E9 38.46 20.68 6 14 2681.68 27.48 7 15 353 39.3 4.58 HVO_2435 peptidase M24 family protein 27.45 1 6 6 20 3.001E8 4.32 27.45 6 10 626.58 27.45 6 10 368 40.0 4.53 HVO_0694 probable phosphoribosyltransferase 27.43 1 6 6 18 9.242E7 8.85 27.43 6 9 820.25 27.43 6 9 237 27.0 4.32 HVO_0424 ABC-type transport system ATP-binding protein 26.99 1 12 12 34 4.434E8 32.07 20.86 10 16 1934.52 26.99 12 18 604 67.2 4.49 HVO_1550 acyl-CoA thioester hydrolase 26.88 1 3 3 7 4.615E8 0.00 20.00 2 3 414.95 26.88 3 4 160 17.6 4.55 HVO_0573 endonuclease IV 26.80 1 5 5 19 6.499E8 8.90 26.80 5 9 970.48 26.80 5 10 291 31.4 4.44 HVO_0581 "cell division protein FtsZ, type II" 26.75 1 7 7 34 6.469E8 30.17 26.75 7 17 1971.69 26.75 7 17 400 42.5 4.75 HVO_1175 DUF2110 family protein 26.67 1 4 4 20 1.014E9 13.19 26.67 4 10 1090.68 26.67 4 10 225 24.4 4.63 HVO_1306 chorismate synthase 26.49 1 7 7 43 3.212E8 34.87 26.49 7 22 1904.60 26.49 7 21 385 41.9 4.83 HVO_2496 adenylate kinase 26.44 1 5 5 30 1.966E9 30.72 26.44 5 15 1988.29 26.44 5 15 208 23.1 4.25 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 26.44 1 9 9 32 4.092E8 18.87 26.44 9 16 1278.62 26.44 9 16 348 38.2 4.32 HVO_1571 DNA topoisomerase VI subunit B 26.19 1 16 16 56 4.097E8 47.84 23.81 15 28 2966.64 24.81 14 28 798 87.4 4.73 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 13 1.746E8 7.87 26.15 3 6 614.49 26.15 3 7 130 13.4 8.56 HVO_1284 GTP cyclohydrolase III 26.05 1 5 5 12 1.751E8 9.89 19.16 4 6 570.72 26.05 5 6 261 28.9 4.70 HVO_1778 catalase-peroxidase 26.04 1 12 12 56 1.954E9 62.24 23.40 11 27 3894.20 26.04 12 29 718 80.0 4.31 HVO_1527 glucose-1-phosphate uridylyltransferase 25.93 1 6 6 30 3.817E8 19.49 25.93 6 15 1435.72 25.93 6 15 243 27.5 4.70 HVO_0466 citrate (si)-synthase 25.86 1 8 8 75 2.541E9 66.82 25.86 8 37 4509.25 25.86 8 38 379 41.8 4.55 HVO_0233 ribose-phosphate pyrophosphokinase 25.80 1 4 4 16 6.138E8 10.87 25.80 4 8 774.95 25.80 4 8 283 29.6 4.40 HVO_1018 RecJ domain protein 25.75 1 14 14 61 1.115E9 42.81 25.75 14 30 3339.98 25.75 14 31 633 69.8 4.58 40354192 keratin 10 [Homo sapiens] 25.34 1 0 15 66 3.963E8 44.55 25.17 14 31 3359.43 23.97 14 35 584 58.8 5.16 HVO_1932 2-D-hydroxyacid dehydrogenase 25.32 1 7 7 31 3.922E8 27.07 25.32 7 16 1340.02 25.32 7 15 308 33.0 4.60 >sp|TRYP_PIG| 25.11 1 4 4 119 4.506E10 146.95 25.11 4 60 9795.59 25.11 4 59 231 24.4 7.18 HVO_2781 DNA-directed RNA polymerase subunit D 25.10 1 5 5 36 1.302E9 30.38 25.10 5 17 1998.32 25.10 5 19 259 28.1 4.32 HVO_0138 tyrosine--tRNA ligase 25.00 1 6 6 25 7.465E8 13.33 20.43 5 12 960.65 25.00 6 13 328 36.1 4.34 HVO_1173 tRNA (cytidine(56)-2'-O)-methyltransferase 25.00 1 3 3 5 6.478E7 2.51 25.00 3 3 139.27 13.89 2 2 180 20.0 4.75 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 24.96 1 0 15 66 3.963E8 44.55 24.79 14 31 3359.43 23.61 14 35 593 59.5 5.21 HVO_0349 DNA-directed RNA polymerase subunit A' 24.59 1 20 20 85 1.068E9 70.85 21.72 18 43 5119.88 23.26 19 42 976 108.8 4.81 HVO_1657 phosphoribosylamine--glycine ligase 24.53 1 8 8 48 1.202E9 41.20 24.53 8 25 2583.17 24.53 8 23 428 45.5 4.20 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 24.39 1 14 14 51 1.009E9 26.57 22.81 13 26 2543.34 21.66 12 25 697 74.5 4.13 HVO_0787 indole-3-glycerol-phosphate synthase 24.30 1 4 4 10 1.171E8 0.00 24.30 4 5 295.20 24.30 4 5 251 26.7 4.44 HVO_1125 cysteine--tRNA ligase 24.09 1 8 8 28 2.125E8 22.52 22.06 7 13 1513.29 24.09 8 15 494 55.2 4.56 HVO_2425 GNAT family acetyltransferase 24.07 1 5 5 18 9.867E8 12.86 24.07 5 9 859.38 20.37 4 9 216 24.4 4.54 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 23.92 1 11 12 31 5.055E8 20.50 23.92 12 16 1298.44 19.90 10 15 623 62.1 5.30 HVO_1370 gamma-glutamyl phosphate reductase 23.87 1 7 7 39 1.265E9 26.92 20.72 6 20 2115.98 23.87 7 19 444 48.1 4.34 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 23.84 1 7 7 34 1.038E9 37.97 21.85 6 16 2486.57 23.84 7 18 453 47.5 4.63 HVO_B0061 precorrin-2 C20-methyltransferase 23.83 1 5 5 20 2.831E8 16.13 23.83 5 10 883.84 23.83 5 10 235 25.3 4.63 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 23.76 1 5 5 21 3.862E8 10.97 17.13 4 10 1133.92 23.76 5 11 362 39.6 4.82 HVO_0600 ACT domain protein 23.73 1 3 3 11 5.136E8 8.43 23.73 3 6 637.12 23.73 3 5 177 19.2 4.44 HVO_0304 electron transfer flavoprotein alpha subunit 23.66 1 4 4 12 1.234E8 5.76 20.50 3 5 470.55 23.66 4 7 317 33.5 4.18 HVO_1025 acetyl-CoA C-acyltransferase 23.50 1 6 6 20 5.759E8 13.38 23.50 6 10 1029.70 23.50 6 10 383 40.7 4.56 HVO_1235 creatininase 23.48 1 4 4 17 1.217E8 11.14 23.48 4 9 662.64 23.48 4 8 264 29.2 4.84 HVO_2639 DUF1611 family protein 23.46 1 5 5 21 2.775E8 15.12 21.11 4 10 958.12 16.13 4 11 341 36.3 4.44 HVO_1087 UspA domain protein 23.40 1 3 3 12 1.072E8 13.03 23.40 3 6 774.46 23.40 3 6 141 15.2 4.98 HVO_2454 anthranilate synthase component I 23.28 1 9 9 35 6.472E8 27.74 21.76 8 17 1811.08 23.28 9 18 524 55.9 4.56 HVO_0087 porphobilinogen synthase 23.24 1 5 5 17 2.100E8 5.12 17.43 4 8 715.88 23.24 5 9 327 35.3 4.72 HVO_0431 HAD superfamily hydrolase 23.24 1 3 3 3 9.825E7 0.00 23.24 3 3 284 30.4 4.26 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 23.15 1 12 12 48 1.019E9 31.45 23.15 11 23 2230.68 22.09 11 25 661 71.0 4.35 HVO_0602 3-dehydroquinate dehydratase 23.08 1 5 5 22 1.904E8 9.34 23.08 5 11 876.75 23.08 5 11 247 27.3 4.51 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 22.97 1 8 8 49 2.375E9 38.77 22.97 8 24 2768.29 22.97 8 25 370 41.9 4.48 HVO_0970 ribulose-bisphosphate carboxylase large subunit 22.95 1 8 8 36 5.377E8 29.80 22.95 8 18 1863.39 18.36 7 18 414 43.9 4.59 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 22.81 1 7 7 26 6.463E8 17.36 22.81 7 14 1475.38 17.30 6 12 526 57.2 4.31 HVO_0519 replication protein A 22.77 1 9 9 43 4.165E8 30.21 22.77 9 21 2162.71 22.77 9 22 483 51.0 4.13 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 22.69 1 7 7 54 2.243E9 39.77 22.69 7 27 2654.91 22.69 7 27 357 40.3 4.40 HVO_2222 CYPL-type peptidylprolyl isomerase 22.67 1 2 2 3 6.804E7 371.53 22.67 2 3 172 18.7 4.44 HVO_A0418 conserved hypothetical protein 22.58 1 3 3 9 4.637E7 4.97 22.58 3 4 556.33 22.58 3 5 155 17.9 4.67 HVO_0661 dCTP deaminase (dUMP-forming) 22.56 1 3 3 14 2.252E8 10.27 22.56 3 7 575.73 22.56 3 7 195 21.2 4.59 HVO_0788 tryptophan synthase beta subunit 22.51 1 7 7 21 9.857E7 4.81 22.51 7 11 574.89 22.51 7 10 422 45.7 4.65 7428712 "keratin 1, type II, cytoskeletal - human" 22.40 1 0 16 88 1.474E9 102.37 22.40 16 44 6156.36 22.40 16 44 643 65.5 6.35 HVO_1547 isoleucine--tRNA ligase 22.34 1 14 14 74 9.722E8 76.77 17.83 12 36 4606.45 22.34 14 38 1043 117.9 4.30 HVO_2793 conserved hypothetical protein 22.22 1 3 3 10 6.652E7 4.06 22.22 3 5 333.22 22.22 3 5 252 27.1 4.46 HVO_3014 origin-associated GTP-binding protein OapA 22.07 1 4 4 9 1.565E8 6.24 22.07 4 5 319.44 13.62 3 4 213 24.0 5.01 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 22.05 1 4 4 11 2.297E8 4.79 22.05 4 5 641.12 22.05 4 6 254 26.9 4.42 HVO_0214 L-lactate dehydrogenase 21.88 1 7 7 41 2.568E9 31.92 21.88 7 20 2475.95 21.88 7 21 320 34.5 4.49 HVO_0402 DUF124 family protein 21.78 1 3 3 8 2.183E8 5.96 21.78 3 4 405.62 21.78 3 4 225 24.0 4.58 HVO_0393 UvrABC system protein A 21.77 1 18 18 73 4.226E8 44.25 21.67 17 36 3135.31 21.77 18 37 983 108.6 4.82 HVO_1478 transcription initiation factor TFB 21.77 1 4 6 26 5.772E8 20.85 21.77 6 13 1617.08 21.77 6 13 317 35.7 5.47 HVO_1496 phosphotransferase system component I 21.77 1 9 9 32 2.641E8 23.84 21.77 9 16 1502.52 21.77 9 16 565 60.3 4.21 HVO_0049 argininosuccinate synthase 21.73 1 8 8 33 2.123E9 18.65 20.00 7 16 1865.69 21.73 8 17 405 44.5 4.34 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 21.72 1 7 7 17 7.268E8 4.21 21.72 7 8 664.63 19.68 6 9 442 46.9 4.58 HVO_1690 DHH family phosphoesterase 21.65 1 6 6 28 8.322E7 22.19 21.65 6 14 1665.11 21.65 6 14 485 52.1 4.48 HVO_1914 acetyl-CoA C-acyltransferase 21.49 1 6 6 29 8.361E8 15.81 18.83 5 14 1598.54 15.38 5 15 377 39.9 4.41 HVO_1967 glucose-6-phosphate isomerase 21.40 1 6 6 18 3.785E8 12.05 20.00 5 9 967.59 16.05 5 9 430 45.6 4.40 HVO_2879 ornithine cyclodeaminase 21.39 1 5 5 13 5.101E8 10.69 13.86 4 6 591.38 21.39 5 7 332 34.6 4.45 HVO_0008 aspartate kinase 21.17 1 6 6 60 3.916E9 42.08 21.17 6 28 3066.61 21.17 6 32 392 41.7 4.46 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 21.13 1 3 3 14 2.553E8 9.69 21.13 3 7 856.57 21.13 3 7 336 36.0 4.51 HVO_2239 UspA domain protein 21.13 1 3 3 7 3.998E8 5.60 21.13 3 4 339.78 13.38 2 3 142 15.4 4.16 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 21.09 1 4 4 14 2.431E8 14.84 21.09 4 7 1100.68 21.09 4 7 294 32.5 4.75 HVO_2707 GFO family oxidoreductase 20.97 1 6 6 24 4.211E8 21.06 20.97 6 12 1015.12 20.97 6 12 372 41.0 4.55 HVO_1853 UspA domain protein 20.95 1 2 2 8 1.270E8 8.16 20.95 2 4 616.65 20.95 2 4 148 16.0 4.58 HVO_2700 AAA-type ATPase (CDC48 subfamily) 20.95 1 14 15 45 4.577E8 24.23 18.97 14 24 1891.12 16.84 13 21 754 82.8 4.75 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 20.88 1 2 2 3 1.562E8 208.49 20.88 2 3 91 10.4 4.07 HVO_1660 DisA-N domain protein 20.82 1 4 4 14 4.358E8 15.21 20.82 4 7 715.45 20.82 4 7 269 28.9 4.73 HVO_1048 phosphoribosylformylglycinamidine synthase 2 20.80 1 9 9 39 5.642E8 39.30 20.80 9 20 2307.83 16.10 8 19 702 72.9 4.18 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 11 4.298E7 15.40 20.71 2 5 945.76 20.71 2 6 140 16.0 5.57 HVO_0699 translation initiation factor aIF-2 alpha subunit 20.68 1 5 5 20 3.376E8 18.25 20.68 5 10 1304.07 20.68 5 10 266 29.5 4.46 HVO_0511 NAD-dependent epimerase/dehydratase 20.61 1 4 4 20 2.328E8 16.88 20.61 4 10 1109.22 20.61 4 10 262 29.3 4.78 HVO_2012 receiver box response regulator 20.61 1 2 2 6 3.343E7 3.92 20.61 2 3 262.15 20.61 2 3 131 14.2 4.74 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 20.61 1 8 8 20 5.368E8 8.53 20.61 8 10 868.42 20.61 8 10 461 50.7 4.73 HVO_0360 30S ribosomal protein S10 20.59 1 2 2 4 1.388E8 0.00 20.59 2 2 122.86 20.59 2 2 102 11.5 4.88 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 20.38 1 4 4 16 9.809E7 15.75 20.38 4 8 889.46 20.38 4 8 265 29.3 4.92 HVO_2790 ATP-binding protein Mrp 20.23 1 4 4 15 3.401E8 6.50 20.23 4 7 671.44 20.23 4 8 346 36.8 4.50 HVO_0358 homoserine dehydrogenase 20.19 1 4 4 21 7.205E8 13.97 20.19 4 11 950.54 20.19 4 10 317 32.4 4.44 HVO_A0012 hypothetical protein 20.13 1 3 3 13 4.364E8 4.47 20.13 3 7 492.48 16.11 2 6 149 17.7 4.54 HVO_B0057 precorrin-3B C17-methyltransferase 20.06 1 3 3 14 4.797E8 16.22 20.06 3 7 996.23 11.05 2 7 344 36.3 4.31 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 19.71 1 3 3 12 2.091E8 10.49 19.71 3 5 695.35 19.71 3 7 208 22.6 4.36 HVO_1338 replication protein A 19.67 1 5 5 19 4.827E8 12.46 19.67 5 9 984.87 19.67 5 10 427 46.0 4.36 HVO_2690 GFO family oxidoreductase 19.67 1 6 6 24 9.670E8 14.31 17.21 5 11 1241.53 19.67 6 13 366 40.0 4.60 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 19.57 1 2 2 10 3.650E8 2.26 19.57 2 5 303.86 19.57 2 5 184 20.0 4.75 HVO_1879 enoyl-CoA hydratase 19.48 1 3 3 5 4.854E7 0.00 8.23 2 2 173.65 19.48 3 3 231 24.3 5.21 HVO_0407 conserved hypothetical protein 19.35 1 2 2 8 3.596E8 8.83 19.35 2 4 463.86 19.35 2 4 124 13.4 4.44 HVO_0017 conserved hypothetical protein 19.27 1 3 3 14 7.632E8 8.26 19.27 3 7 803.29 19.27 3 7 192 21.9 4.50 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 19.24 1 8 8 34 8.350E8 22.04 19.24 8 16 1855.04 19.24 8 18 447 48.5 4.56 HVO_1783 conserved hypothetical protein 19.20 1 3 3 9 4.004E7 4.53 19.20 3 4 366.73 19.20 3 5 224 24.1 5.90 HVO_1412 diphosphomevalonate decarboxylase 19.14 1 6 6 38 1.589E9 14.47 19.14 6 19 1530.47 19.14 6 19 324 35.4 4.78 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 19.10 1 3 4 7 1.120E8 4.04 12.73 3 3 318.15 19.10 4 4 267 28.8 4.55 HVO_0658 tRNA pseudouridine(13) synthase TruD 19.01 1 5 5 12 1.064E8 7.45 19.01 5 6 417.38 19.01 5 6 463 50.6 4.70 HVO_0415 repair helicase 18.99 1 9 9 27 1.017E9 15.70 18.99 9 12 1540.23 18.99 9 15 616 69.6 4.70 HVO_2417 conserved hypothetical protein 18.97 1 3 3 9 5.071E8 8.48 18.97 3 5 434.74 18.97 3 4 195 21.6 3.65 HVO_1289 OsmC domain protein 18.94 1 2 2 12 2.233E9 15.19 18.94 2 6 963.08 18.94 2 6 132 14.2 3.85 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 18.90 1 5 5 12 6.353E7 2.22 11.92 3 5 634.78 18.90 5 7 344 39.1 4.73 HVO_1816 dihydroorotase 18.88 1 6 6 18 1.293E8 11.07 18.88 6 9 626.19 18.88 6 9 429 45.4 4.40 HVO_0697 PAC2 family protein 18.82 1 2 2 14 3.680E8 12.28 18.82 2 7 584.64 18.82 2 7 255 27.4 4.08 HVO_2467 NADPH:quinone reductase 18.69 1 4 4 10 9.414E7 9.10 18.69 4 5 534.22 18.69 4 5 321 33.0 4.51 HVO_0736 DUF302 family protein 18.54 1 2 2 2 7.593E8 100.12 18.54 2 2 151 16.4 4.30 HVO_1698 CBS/parB domain protein 18.49 1 2 3 7 1.904E9 0.00 18.49 3 4 188.71 16.60 2 3 265 29.4 4.92 HVO_0123 signal recognition particle 54K protein 18.28 1 7 7 22 3.176E8 3.04 16.13 6 10 958.70 18.28 7 12 465 50.9 4.50 HVO_1437 conserved hypothetical protein 18.23 1 3 3 6 1.188E8 0.00 18.23 3 3 180.95 18.23 3 3 203 22.3 4.94 HVO_B0055 conserved hypothetical protein 18.22 1 3 3 7 1.064E8 6.77 18.22 3 4 311.25 18.22 3 3 225 23.9 4.69 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 18.14 1 7 7 21 2.112E8 18.44 15.62 6 10 970.12 18.14 7 11 634 66.1 4.54 HVO_B0375 Spo0M family protein 17.96 1 2 2 2 9.005E7 126.14 17.96 2 2 245 27.2 4.35 HVO_2156 UspA domain protein 17.94 1 4 4 18 6.692E8 17.49 17.94 4 9 1277.89 17.94 4 9 301 31.6 4.69 HVO_0467 PhoU/TrkA-C domain protein 17.91 1 6 6 15 2.211E8 6.09 13.93 5 7 780.76 17.91 6 8 402 43.3 4.49 HVO_2383 DNA repair and recombination protein RadB 17.90 1 3 3 8 4.350E7 7.12 17.90 3 4 486.92 17.90 3 4 229 24.6 5.02 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 17.87 1 6 6 33 4.851E8 16.28 17.87 6 17 1111.19 17.87 6 16 347 36.8 4.93 HVO_2348 GTP cyclohydrolase MptA 17.86 1 4 4 18 1.425E8 6.95 12.66 3 9 523.94 17.86 4 9 308 33.5 4.68 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 17.84 1 3 3 13 4.308E8 11.26 17.84 3 6 631.64 17.84 3 7 269 28.3 4.49 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 17.83 1 5 5 9 1.483E8 1.88 13.99 4 4 316.97 17.83 5 5 286 30.8 4.46 HVO_2614 uridine phosphorylase 17.77 1 3 3 30 1.547E9 18.08 17.77 3 14 1503.86 17.77 3 16 242 25.8 4.30 HVO_1965 rRNA maturation endonuclease Nob1 17.76 1 2 2 4 2.422E7 2.05 17.76 2 2 137.61 17.76 2 2 152 16.8 4.70 HVO_1377 UPF0145 family protein 17.74 1 2 2 2 3.766E8 1.84 17.74 2 2 124 12.8 4.37 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 17.70 1 4 4 10 5.290E8 7.27 17.70 4 5 515.95 17.70 4 5 339 38.1 4.50 HVO_2948 phenylalanine--tRNA ligase alpha subunit 17.43 1 5 5 22 4.649E8 13.84 16.23 4 10 716.42 17.43 5 12 499 55.1 4.41 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 17.38 1 3 3 10 3.616E7 3.87 17.38 3 5 389.17 17.38 3 5 305 34.1 4.91 HVO_1792 Lrp/AsnC family transcription regulator 17.28 1 2 2 6 1.970E8 7.38 17.28 2 3 424.30 17.28 2 3 162 18.1 4.34 HVO_2008 archaeosine synthase 17.26 1 9 9 28 6.727E8 11.00 17.26 9 14 1046.77 17.26 9 14 585 64.9 4.81 HVO_2756 50S ribosomal protein L10 17.24 1 5 5 35 5.428E8 25.23 17.24 5 18 1637.21 17.24 4 17 348 36.9 3.99 HVO_1446 "fructose-1,6-bisphosphatase" 17.17 1 3 3 8 1.404E8 9.67 17.17 3 4 548.84 17.17 3 4 297 31.6 4.45 HVO_1623 conserved hypothetical protein 17.11 1 4 4 11 6.978E7 5.93 17.11 4 6 442.21 10.40 3 5 298 32.8 4.56 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 17.06 1 17 17 60 5.512E8 37.61 17.06 17 29 2636.29 17.06 17 31 1284 141.2 4.35 HVO_B0114 IclR family transcription regulator 17.06 1 4 4 11 1.135E8 9.80 13.49 3 5 646.18 17.06 4 6 252 28.4 5.44 HVO_1508 acetolactate synthase large subunit 17.04 1 6 6 21 2.289E8 15.93 12.61 5 11 1026.67 17.04 6 10 587 62.3 4.36 HVO_A0406 conserved hypothetical protein 17.04 1 1 5 21 3.797E8 9.74 17.04 5 10 854.90 17.04 5 11 405 44.4 5.30 HVO_C0069 GFO family oxidoreductase 16.98 1 6 6 22 1.320E8 13.69 16.98 6 11 849.45 16.98 6 11 324 36.0 5.10 HVO_A0486 hydrogenase expression/formation protein 16.96 1 3 3 6 4.990E7 2.23 11.90 2 3 163.08 12.50 2 3 336 33.8 4.06 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 16.89 1 6 6 25 1.162E9 13.12 16.89 6 12 1205.26 16.89 6 13 373 40.2 4.44 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 16.78 1 6 6 20 2.446E8 8.56 13.24 5 10 779.90 16.78 6 10 423 43.9 4.31 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 16.74 1 5 5 12 1.587E8 7.89 10.70 4 5 462.66 16.74 5 7 430 45.1 4.50 HVO_0812 phosphoenolpyruvate synthase 16.69 1 9 9 27 3.418E8 23.90 15.24 8 12 1620.67 16.69 9 15 761 83.1 4.63 HVO_0043 acetylornithine aminotransferase 16.67 1 4 4 14 3.691E8 9.47 16.67 4 7 905.96 16.67 4 7 378 39.7 4.67 HVO_2858 Lrp/AsnC family transcription regulator 16.67 1 3 3 10 7.083E7 5.83 16.67 3 5 376.61 16.67 3 5 156 17.6 4.61 HVO_2266 hypothetical protein 16.63 1 5 5 37 2.762E8 14.49 16.63 5 19 1652.72 16.63 5 18 493 56.7 4.54 HVO_1568 alpha/beta hydrolase fold protein 16.61 1 3 3 7 1.398E8 4.46 16.61 3 4 282.39 7.94 2 3 277 29.4 4.94 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 16.47 1 0 2 6 5.943E8 0.00 16.47 2 3 280.71 16.47 2 3 85 10.0 5.94 HVO_2923 proteasome alpha subunit 16.47 1 3 4 16 3.746E8 9.02 16.47 4 8 818.82 16.47 4 8 249 26.7 4.39 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 16.42 1 6 6 24 3.831E8 15.88 16.42 6 12 981.84 16.42 6 12 615 67.6 4.88 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 16.39 1 3 3 6 1.270E8 2.41 16.39 3 3 194.48 8.85 2 3 305 32.7 4.56 HVO_0712 shikimate dehydrogenase (nonfunctional) 16.36 1 3 3 6 4.578E7 1.71 16.36 3 3 156.05 16.36 3 3 269 27.7 4.65 HVO_A0485 aminotransferase class V 16.24 1 4 4 14 2.489E8 17.39 16.24 4 7 947.44 16.24 4 7 351 37.3 4.26 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 16.18 1 5 5 14 1.674E8 1.98 16.18 5 7 405.21 10.37 4 7 482 50.6 4.31 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 16.02 1 3 3 8 1.406E8 2.41 16.02 3 4 418.72 16.02 3 4 231 25.0 4.25 HVO_1880 conserved hypothetical protein 16.00 1 3 3 10 4.545E7 10.45 16.00 3 5 680.69 16.00 3 5 225 23.8 4.59 HVO_2717 alanine--tRNA ligase 15.83 1 6 6 22 1.765E8 11.84 12.81 5 9 1338.36 15.83 6 13 398 41.6 4.39 HVO_1725 Orc1-type DNA replication protein 15.71 1 4 4 6 3.567E7 1.67 5.49 2 2 170.68 15.71 4 4 401 44.5 5.19 HVO_1348 probable YjeF family carbohydrate kinase 15.69 1 4 4 15 1.555E8 11.05 15.69 4 7 737.99 15.69 4 8 478 48.8 4.45 HVO_1866 uridylate kinase 15.61 1 3 3 17 7.514E8 8.68 15.61 3 9 737.91 15.61 3 8 237 24.6 4.42 HVO_1295 histidinol-phosphate aminotransferase 15.51 1 4 4 12 2.495E8 11.26 15.51 4 6 764.77 15.51 4 6 361 39.4 4.51 HVO_A0350 conserved hypothetical protein 15.49 1 3 3 6 3.057E7 2.45 15.49 3 3 314.82 15.49 3 3 213 23.8 9.64 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 15.46 1 4 4 16 3.159E8 12.41 15.46 4 8 813.84 15.46 4 8 427 45.4 4.56 HVO_0452 leucine--tRNA ligase 15.45 1 12 12 37 4.472E8 24.63 9.92 8 17 1838.91 15.45 12 20 958 109.5 4.37 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 15.43 1 12 12 36 2.349E8 27.05 13.22 10 17 2709.04 13.59 11 19 1082 117.2 4.32 HVO_1098 diaminopimelate decarboxylase 15.42 1 4 4 10 2.615E8 4.59 15.42 4 6 266.61 9.16 3 4 415 44.4 5.02 HVO_1574 NUDIX family hydrolase 15.38 1 2 2 7 1.303E8 0.00 15.38 2 4 125.69 15.38 2 3 156 17.6 4.98 HVO_0158 TATA-binding transcription initiation factor 15.34 1 2 3 20 8.272E8 5.15 15.34 3 12 661.42 15.34 3 8 189 20.3 4.22 HVO_A0087 fumarylacetoacetase family protein 15.22 1 3 3 4 2.695E8 2.57 13.49 2 2 207.14 8.30 2 2 289 32.0 4.21 HVO_1073 ThiJ/PfpI family protein 15.18 1 3 3 11 6.987E7 7.31 15.18 3 5 533.94 15.18 3 6 224 23.9 4.12 HVO_0406 RNA-binding protein AU-1 15.17 1 5 5 14 7.164E7 6.49 15.17 5 7 521.52 15.17 5 7 468 49.9 4.53 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 15.09 1 3 3 11 3.037E8 11.65 15.09 3 6 630.04 15.09 3 5 265 28.7 4.87 HVO_2648 phosphoglycerate dehydrogenase 15.05 1 3 3 10 1.237E8 7.60 15.05 3 5 341.85 15.05 3 5 319 34.2 4.64 HVO_2763 homolog to ribonuclease Z 14.92 1 3 3 11 2.001E8 8.50 14.92 3 6 520.61 14.92 3 5 248 26.6 4.53 HVO_2313 siroheme decarboxylase AhbB 14.73 1 2 2 9 3.859E8 8.87 14.73 2 4 601.44 14.73 2 5 353 39.6 4.64 HVO_1654 cysteine synthase 14.71 1 3 3 8 3.072E8 4.64 14.71 3 4 284.84 14.71 3 4 306 32.3 4.32 HVO_B0018 ParA domain protein 14.63 1 2 2 4 9.688E7 0.00 14.63 2 2 133.36 14.63 2 2 287 31.7 4.74 HVO_2481 HD family hydrolase 14.62 1 3 3 8 1.701E8 6.33 14.62 3 4 294.62 14.62 3 4 390 42.7 6.14 HVO_2947 phenylalanine--tRNA ligase beta subunit 14.56 1 7 7 35 8.891E8 9.84 11.40 5 14 1588.69 14.56 7 21 570 63.3 4.46 HVO_2373 30S ribosomal protein S8e 14.40 1 2 2 3 9.785E7 136.02 14.40 2 3 125 13.6 10.48 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 14.18 1 3 3 7 6.981E7 5.02 14.18 3 4 250.99 14.18 3 3 268 27.9 4.87 HVO_2421 probable DNA-binding protein 14.04 1 3 3 5 2.094E8 1.60 7.66 2 2 165.57 14.04 3 3 235 25.8 4.89 HVO_2205 arNOG06768 family NADH-binding domain protein 13.95 1 3 3 8 2.365E7 9.37 13.95 3 4 521.74 13.95 3 4 301 32.0 5.00 HVO_0867 HD family hydrolase 13.91 1 3 3 10 1.134E8 6.65 13.91 3 5 515.72 13.91 3 5 230 26.2 4.78 HVO_2600 methionyl aminopeptidase 13.85 1 4 4 12 3.051E8 12.28 9.80 3 5 819.20 13.85 4 7 296 32.3 4.41 HVO_1553 hydroxypyruvate reductase 13.80 1 5 5 12 1.150E8 2.27 13.80 5 6 360.65 13.80 5 6 442 45.2 4.50 HVO_1491 HAD superfamily hydrolase 13.73 1 5 5 17 1.126E8 5.69 11.03 4 8 768.06 13.73 5 9 408 44.4 4.60 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 10 1.964E8 4.54 13.66 2 5 583.54 13.66 2 5 183 20.0 4.21 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 13.58 1 4 4 13 1.905E8 10.36 9.88 3 6 922.83 13.58 4 7 324 36.6 4.68 HVO_0326 CTP-dependent riboflavin kinase 13.50 1 3 3 10 2.662E7 6.20 13.50 3 5 444.92 13.50 3 5 237 25.9 4.55 HVO_2536 CHP00300 family protein 13.46 1 3 3 9 2.384E8 2.70 13.46 3 4 216.57 13.46 3 5 416 44.8 4.51 HVO_B0117 conserved hypothetical protein 13.46 1 2 2 4 1.399E7 3.61 13.46 2 2 148.34 13.46 2 2 208 23.3 4.58 HVO_0681 DNA topoisomerase I 13.45 1 9 9 25 1.011E8 10.07 10.83 7 11 1160.61 13.45 9 14 840 93.6 4.58 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 13.45 1 3 3 18 3.365E8 1.98 13.45 3 9 539.96 13.45 3 9 357 39.8 4.41 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 13.45 1 2 2 6 2.388E8 1.76 13.45 2 3 224.04 13.45 2 3 238 24.7 4.15 HVO_1685 conserved hypothetical protein 13.41 1 6 6 20 2.462E8 7.58 13.41 6 10 714.52 13.41 6 10 492 54.5 5.74 HVO_2716 acyl-CoA dehydrogenase 13.39 1 3 3 10 1.262E8 11.88 13.39 3 5 520.74 13.39 3 5 381 41.3 4.65 HVO_1503 3-isopropylmalate dehydratase small subunit 13.37 1 2 2 3 1.748E8 4.07 13.37 2 3 202 22.0 4.15 HVO_1957 proteasome-activating nucleotidase 13.35 1 4 4 11 7.257E7 4.39 8.25 3 5 486.38 13.35 4 6 412 45.6 4.48 HVO_1407 HTH domain protein 13.33 1 2 2 6 1.024E8 0.00 13.33 2 3 197.91 13.33 2 3 225 24.9 4.45 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 13.33 1 3 3 7 5.899E7 5.36 10.28 2 3 365.17 13.33 3 4 360 38.5 4.45 HVO_0048 argininosuccinate lyase 13.32 1 4 4 8 8.368E7 4.94 9.63 3 3 375.64 13.32 4 5 488 50.8 4.53 HVO_1337 rpa-associated protein 13.32 1 7 7 21 8.057E8 14.98 13.32 7 12 912.95 8.35 4 9 623 64.8 3.68 HVO_0054 glycine--tRNA ligase 13.30 1 5 5 19 2.078E9 17.25 10.94 4 9 1519.82 9.93 4 10 594 64.9 4.21 HVO_1080 conserved hypothetical protein 13.30 1 2 3 11 4.053E8 2.10 13.30 3 5 455.72 13.30 3 6 188 21.1 4.31 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 13.28 1 5 5 19 2.081E8 18.79 13.28 5 9 1038.57 13.28 5 10 512 53.8 4.78 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 13.27 1 3 3 10 1.066E8 1.63 13.27 3 5 264.49 13.27 3 5 422 43.6 4.72 HVO_0354 30S ribosomal protein S7 13.24 1 2 2 8 6.223E8 7.79 13.24 2 4 602.66 13.24 2 4 204 22.6 5.14 HVO_1570 DNA topoisomerase VI subunit A 13.11 1 4 4 12 3.095E8 4.31 13.11 4 6 625.94 13.11 4 6 366 41.8 4.63 HVO_0491 FMN-binding domain protein 13.07 1 3 3 5 2.931E7 1.73 13.07 2 2 180.46 13.07 3 3 153 17.3 4.67 HVO_0321 peptide chain release factor aRF-1 13.04 1 5 5 15 2.204E8 11.42 13.04 5 8 742.25 13.04 5 7 414 46.6 4.83 HVO_2412 Lrp/AsnC family transcription regulator 13.04 1 2 2 3 7.908E7 147.14 13.04 2 3 161 17.7 4.55 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 13.00 1 3 3 17 1.596E8 8.02 10.83 2 8 741.55 13.00 3 9 277 30.6 4.30 HVO_1371 glutamate 5-kinase 12.96 1 2 2 6 3.191E8 2.46 12.96 2 3 293.56 12.96 2 3 301 32.0 4.25 HVO_0591 L-threonine-O-3-phosphate decarboxylase 12.94 1 2 2 2 6.363E7 2.06 12.94 2 2 340 36.0 4.54 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 12.91 1 4 5 13 2.349E8 7.86 11.41 4 6 715.69 12.91 5 7 333 36.7 4.56 HVO_B0066 Lrp/AsnC family transcription regulator 12.80 1 2 2 3 6.010E7 270.18 12.80 2 3 164 18.5 4.41 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 12.75 1 4 4 9 1.688E8 0.00 12.75 4 5 250.59 10.72 3 4 345 36.9 4.68 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 12.66 1 2 2 2 5.113E8 0.00 12.66 2 2 237 25.4 4.46 HVO_1268 conserved hypothetical protein 12.66 1 2 2 6 6.146E7 3.56 12.66 2 3 113.95 12.66 2 3 237 26.4 5.21 HVO_2333 conserved hypothetical protein 12.66 1 5 5 12 1.643E8 2.06 12.66 5 6 416.08 12.66 5 6 308 34.9 4.54 HVO_1510 2-isopropylmalate synthase 12.50 1 2 2 14 1.850E9 17.48 12.50 2 7 960.56 12.50 2 7 440 47.7 4.82 HVO_1594 tRNA/rRNA cytosine-C5-methylase 12.46 1 3 3 8 1.399E8 4.48 12.46 3 4 450.14 12.46 3 4 313 34.6 4.69 HVO_2168 AAA-type ATPase (MoxR subfamily) 12.46 1 3 3 10 1.166E8 7.94 12.46 3 5 458.46 12.46 3 5 329 35.9 4.54 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 12.41 1 3 3 8 1.151E8 3.69 12.41 3 4 318.28 12.41 3 4 266 29.7 4.32 HVO_2906 tRNA (cytidine/uridine-2'-O-)-methyltransferase 12.36 1 2 2 2 4.775E7 112.92 12.36 2 2 275 30.6 4.58 HVO_2547 50S ribosomal protein L32e 12.34 1 2 2 4 3.552E7 3.19 12.34 2 2 215.58 12.34 2 2 235 25.8 4.75 HVO_0916 diphthine synthase 12.27 1 2 2 2 2.071E8 1.69 12.27 2 2 269 29.1 4.54 HVO_0475 conserved hypothetical protein 12.18 1 2 2 2 7.384E7 83.33 12.18 2 2 312 32.5 4.74 47132620 keratin 2a [Homo sapiens] 12.05 1 4 8 35 9.933E8 30.34 12.05 8 18 2201.60 10.17 7 17 639 65.4 8.00 HVO_0122 phosphoglycerate dehydrogenase 12.04 1 3 3 11 2.660E7 12.78 12.04 3 6 530.60 12.04 3 5 324 35.3 5.35 HVO_2158 malic enzyme (NADP) 11.98 1 1 4 13 1.200E8 6.16 11.98 4 7 528.31 9.59 3 6 751 81.4 4.55 HVO_2784 30S ribosomal protein S13 11.98 1 2 2 6 2.621E8 6.79 11.98 2 3 379.02 11.98 2 3 167 18.9 5.17 HVO_1174 transcription initiation factor TFE 11.93 1 2 2 4 1.244E8 414.17 11.93 2 4 176 20.6 4.23 HVO_2662 homolog to lactoylglutathione lyase 11.85 1 3 3 11 5.568E7 14.91 11.85 3 6 825.82 7.60 2 5 329 36.5 4.48 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 11.80 1 9 9 21 3.172E8 12.92 10.47 8 10 931.83 10.80 8 11 898 97.7 4.45 HVO_2610 deoxyribose-phosphate aldolase 11.79 1 2 2 4 1.589E8 0.00 11.79 2 2 112.77 11.79 2 2 212 21.9 4.23 HVO_A0266 IclR family transcription regulator 11.76 1 2 2 8 5.246E7 8.76 11.76 2 4 539.85 11.76 2 4 255 27.7 6.05 HVO_0228 ParA domain protein 11.74 1 2 2 4 3.520E8 376.31 11.74 2 4 247 24.6 4.16 HVO_1327 AAA-type ATPase (CDC48 subfamily) 11.68 1 5 6 17 3.212E8 13.64 8.70 5 8 903.27 11.68 6 9 736 78.1 4.88 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 11.64 1 4 4 12 1.050E8 5.67 11.64 4 6 613.32 11.64 4 6 378 39.8 4.45 HVO_0818 threonine synthase 11.57 1 4 4 19 5.415E8 8.72 7.97 3 9 906.34 11.57 4 10 389 40.8 4.31 HVO_2001 tRNA-guanine(15) transglycosylase 11.43 1 3 3 10 8.172E7 6.22 11.43 3 5 309.45 11.43 3 5 516 56.3 4.59 HVO_1824 conserved hypothetical protein 11.42 1 3 3 13 2.205E8 10.49 11.42 3 6 440.45 11.42 3 7 429 47.4 4.20 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 11.42 1 3 3 11 1.306E8 6.42 11.42 3 5 388.30 11.42 3 6 464 53.1 4.54 HVO_2072 S-layer glycoprotein 11.37 1 4 4 49 2.875E9 30.15 11.37 4 26 1427.47 11.37 4 23 827 85.1 3.65 HVO_A0432 conserved hypothetical protein 11.36 1 0 4 16 1.325E8 9.74 11.36 4 8 737.92 11.36 4 8 405 44.5 5.24 HVO_0853 DNA double-strand break repair protein Mre11 11.34 1 3 3 9 1.858E8 6.06 7.94 2 4 401.38 11.34 3 5 441 48.1 4.39 HVO_1344 SBDS family protein 11.34 1 2 2 8 7.665E7 5.96 11.34 2 4 425.55 11.34 2 4 238 26.5 4.51 HVO_1804 nicotinate phosphoribosyltransferase 11.34 1 4 4 8 1.662E8 1.67 5.15 2 3 370.91 11.34 4 5 388 41.1 4.60 HVO_1847 oligoendopeptidase PepF 11.19 1 5 5 12 6.151E7 7.25 11.19 5 6 580.08 7.51 4 6 599 68.5 4.41 HVO_2456 anthranilate phosphoribosyltransferase 11.18 1 2 2 9 5.154E7 3.90 11.18 2 5 279.89 11.18 2 4 331 33.8 4.35 HVO_1531 UDP-glucose 6-dehydrogenase 11.16 1 4 4 18 1.926E8 6.94 11.16 4 9 752.13 11.16 4 9 430 45.9 4.50 HVO_2702 alpha/beta hydrolase fold protein 11.15 1 2 2 6 5.996E7 5.47 11.15 2 3 257.58 11.15 2 3 260 28.0 4.53 HVO_2918 thymidylate synthase 11.14 1 2 2 3 1.222E8 7.59 11.14 2 3 332 37.5 4.61 HVO_1097 diaminopimelate epimerase 11.11 1 1 2 3 8.998E7 3.86 11.11 2 3 288 29.9 4.48 HVO_1928 5-formyltetrahydrofolate cyclo-ligase 11.11 1 2 2 4 3.878E7 2.03 11.11 2 2 95.84 11.11 2 2 243 26.5 4.69 HVO_0041 ornithine carbamoyltransferase 11.04 1 3 3 11 2.324E8 7.08 11.04 3 6 609.35 11.04 3 5 299 32.7 4.37 HVO_2256 DUF262 family protein 11.04 1 5 5 15 1.557E8 13.83 11.04 5 7 845.61 11.04 5 8 462 54.9 4.89 HVO_A0458 ParA domain protein 11.00 1 2 2 4 3.841E8 2.44 11.00 2 2 241.04 11.00 2 2 291 32.2 4.79 HVO_2160 conserved hypothetical protein 10.99 1 16 16 132 3.798E9 171.29 10.99 16 67 11089.53 10.50 15 65 2257 232.7 3.92 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 10.96 1 3 3 10 1.550E8 3.70 10.96 3 5 371.91 10.96 3 5 365 39.0 4.61 HVO_0826 peptidase M42 family protein 10.92 1 2 2 6 7.627E7 1.94 10.92 2 3 213.39 10.92 2 3 348 37.7 4.54 HVO_2945 valine--tRNA ligase 10.92 1 8 8 34 3.609E8 18.15 9.43 7 15 2255.61 10.92 8 19 870 98.9 4.36 HVO_B0038A D-xylonate dehydratase 10.92 1 1 3 9 2.442E8 3.67 4.61 2 4 427.55 10.92 3 5 412 45.5 4.55 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 10.86 1 2 2 6 4.045E9 5.24 10.86 2 3 283.38 10.86 2 3 175 18.8 4.63 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 10.86 1 1 2 4 2.668E8 2.05 10.86 2 2 218.38 10.86 2 2 267 29.1 4.63 HVO_0745 "FtsZ family protein, type III" 10.83 1 3 3 7 1.013E8 4.38 10.83 3 3 330.67 10.83 3 4 360 37.1 4.51 HVO_0670 glutathione S-transferase 10.74 1 3 3 4 9.515E7 0.00 6.13 2 2 81.50 7.06 2 2 326 38.1 4.56 HVO_2581 quinolinate synthase A 10.65 1 4 4 11 1.978E8 1.80 8.31 3 5 403.37 10.65 4 6 385 42.0 4.41 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 10.63 1 3 3 6 1.476E8 401.94 10.63 3 6 395 42.4 4.54 HVO_2721 amidophosphoribosyltransferase 10.55 1 4 4 20 5.701E8 3.39 10.55 4 10 665.49 10.55 4 10 493 53.4 4.78 HVO_A0498 conserved hypothetical protein 10.55 1 3 4 6 2.705E8 0.00 7.39 3 3 181.78 8.44 3 3 379 42.7 4.55 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 10.39 1 3 3 10 1.419E8 7.55 10.39 3 5 387.24 10.39 3 5 337 35.9 4.69 HVO_2153 probable copper-containing oxidoreductase 10.39 1 2 2 3 6.631E7 394.14 10.39 2 3 385 42.1 5.82 HVO_1139 squalene synthase 10.34 1 2 2 6 1.231E8 0.00 10.34 2 3 204.52 10.34 2 3 358 39.7 4.54 HVO_0893 methylmalonyl-CoA mutase subunit A 10.25 1 4 4 16 9.350E7 6.92 10.25 4 8 863.08 10.25 4 8 566 63.1 4.36 HVO_1567 conserved hypothetical protein 10.21 1 2 2 3 2.314E8 250.97 10.21 2 3 235 25.7 4.36 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 10.19 1 2 2 6 7.465E8 0.00 10.19 2 3 63.07 10.19 2 3 363 39.7 4.25 HVO_B0052 PQQ repeat protein 10.19 1 4 4 13 1.127E8 2.83 10.19 4 6 508.22 10.19 4 7 412 44.1 5.48 HVO_0044 acetylglutamate kinase 10.09 1 2 2 6 6.098E7 7.37 10.09 2 3 427.80 10.09 2 3 327 33.2 4.49 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 10.02 1 3 3 8 1.287E8 2.32 10.02 3 4 401.64 10.02 3 4 459 50.5 4.63 HVO_1129 conserved hypothetical protein 10.00 1 2 2 6 1.819E8 7.20 10.00 2 3 256.42 10.00 2 3 390 43.0 4.44 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 6 1.291E8 5.87 10.00 2 3 366.89 10.00 2 3 190 21.0 4.74 HVO_0719 transcription elongation factor Spt5/NusG 10.00 1 2 2 4 2.943E8 408.96 10.00 2 4 150 16.3 4.50 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 9.96 1 0 5 18 2.732E8 8.61 7.20 4 8 1126.58 9.96 5 10 472 51.6 5.16 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 9.96 1 2 2 8 1.227E8 9.72 9.96 2 4 481.99 9.96 2 4 261 27.0 4.44 HVO_0464 threonine ammonia-lyase 9.93 1 3 3 7 6.499E7 2.95 6.70 2 3 299.00 9.93 3 4 403 43.7 4.72 HVO_A0551 acyl-CoA synthetase 9.85 1 4 4 8 6.007E7 4.31 9.85 4 4 430.51 9.85 4 4 538 59.6 4.65 HVO_1323 "shikimate kinase, archaeal-type" 9.69 1 2 2 13 7.365E8 16.26 9.69 2 7 915.48 9.69 2 6 289 29.5 4.30 HVO_B0060 precorrin-4 C11-methyltransferase 9.68 1 2 2 7 5.250E8 3.80 9.68 2 4 324.46 9.68 2 3 279 29.7 4.22 HVO_B0149 oleate hydratase 9.57 1 3 4 8 2.216E8 0.00 6.19 2 3 285.05 9.57 4 5 533 60.1 4.64 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 9.52 1 2 2 11 2.156E8 8.45 9.52 2 6 380.19 9.52 2 5 189 21.7 4.46 HVO_2501 alpha/beta hydrolase fold protein 9.49 1 2 2 8 3.080E7 7.34 9.49 2 4 383.98 9.49 2 4 316 35.3 5.72 HVO_A0003 ParA domain protein 9.49 1 2 2 2 2.527E7 76.31 9.49 2 2 274 30.3 4.53 HVO_0322 MinD/ParA domain protein 9.47 1 3 3 7 2.353E8 0.00 9.47 3 4 163.54 8.09 2 3 581 58.8 3.70 HVO_B0200 malate synthase 9.40 1 2 2 3 4.784E8 5.70 9.40 2 3 436 48.3 4.30 HVO_0454 ornithine cyclodeaminase 9.37 1 2 2 4 5.439E7 1.67 9.37 2 2 120.29 9.37 2 2 331 35.6 4.23 HVO_0551 DNA mismatch repair protein MutL 9.25 1 4 4 14 1.281E8 7.88 9.25 4 7 480.75 9.25 4 7 735 78.7 4.50 HVO_2068 "FtsZ family protein, type III" 9.19 1 2 2 2 1.378E8 202.55 9.19 2 2 370 38.7 4.49 HVO_1236 acyl-CoA synthetase 9.16 1 3 3 5 2.210E8 0.00 3.74 2 2 204.18 9.16 3 3 535 59.1 4.60 HVO_0572 lipoate-protein ligase 9.09 1 2 2 6 2.193E7 6.42 9.09 2 3 467.72 9.09 2 3 275 30.5 4.84 HVO_1374 acyl-CoA synthetase 8.86 1 4 4 10 3.838E8 10.16 4.34 2 4 705.65 8.86 4 6 553 61.1 4.50 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 8.85 1 0 4 15 1.351E8 11.42 8.85 4 8 814.87 5.73 3 7 384 42.4 5.40 HVO_1465 naphthoate synthase 8.85 1 2 2 3 2.576E8 209.94 8.85 2 3 305 33.9 4.83 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 8.80 1 0 4 9 3.018E8 2.55 5.79 3 4 476.17 8.80 4 5 432 48.1 5.02 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 8.71 1 2 2 6 6.085E7 4.80 8.71 2 3 183.70 8.71 2 3 287 31.8 4.93 HVO_1453 glutamate dehydrogenase (NADP) 8.63 1 4 4 13 2.391E8 6.79 8.63 4 7 519.13 6.47 3 6 417 45.7 4.49 HVO_1578 probable NADH dehydrogenase 8.56 1 2 2 3 6.819E7 357.44 8.56 2 3 397 42.8 4.40 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 8.53 1 3 3 5 1.052E8 0.00 5.80 2 2 130.76 8.53 3 3 586 63.4 4.70 HVO_B0115 fumarylacetoacetase family protein 8.48 1 2 2 3 3.541E8 330.42 8.48 2 3 283 30.3 4.21 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 8.43 1 2 2 7 6.036E7 5.54 8.43 2 3 471.87 8.43 2 4 344 37.0 4.55 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 8.36 1 3 3 15 3.278E8 4.38 6.69 2 7 642.93 8.36 3 8 299 32.0 4.53 HVO_2960 dihydrolipoamide S-acyltransferase 8.25 1 4 4 9 3.352E7 3.92 6.33 3 4 400.91 8.25 4 5 521 54.9 4.40 HVO_B0324 conserved hypothetical protein 8.24 1 3 3 8 5.597E7 2.16 8.24 3 4 304.47 8.24 3 4 449 48.0 4.58 HVO_0868 NAD-dependent epimerase/dehydratase 8.21 1 3 3 11 1.728E8 0.00 8.21 3 4 403.43 8.21 3 7 329 36.1 4.55 HVO_1372 pyrroline-5-carboxylate reductase 8.17 1 2 2 6 2.162E8 5.75 8.17 2 3 490.25 8.17 2 3 257 26.8 4.01 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 8.14 1 3 3 28 5.196E8 15.99 8.14 3 13 1758.30 8.14 3 15 430 44.2 4.37 HVO_2321 bacterial-type DNA primase DnaG 8.05 1 3 3 8 1.043E8 4.52 8.05 3 4 383.08 8.05 3 4 472 49.4 4.36 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 8.02 1 2 2 7 4.316E7 6.65 8.02 2 3 422.02 8.02 2 4 349 37.0 4.70 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 8.01 1 2 2 7 4.509E7 2.41 8.01 2 4 214.74 8.01 2 3 574 62.8 4.17 HVO_0215 iron-sulfur protein (4Fe-4S) 7.95 1 2 2 2 1.700E8 57.51 7.95 2 2 704 78.2 4.58 21961227 Keratin 6B [Homo sapiens] 7.80 1 0 5 23 3.150E8 20.88 7.80 5 12 1232.81 5.67 4 11 564 60.0 8.00 HVO_0194 Orc1-type DNA replication protein 7.75 1 3 3 8 1.871E8 1.85 4.01 2 3 287.19 7.75 3 5 374 42.2 4.94 HVO_B0371 aldehyde dehydrogenase 7.66 1 2 2 4 6.260E7 3.55 7.66 2 2 143.39 7.66 2 2 496 52.5 4.39 HVO_1356 sensor box histidine kinase 7.64 1 2 2 8 1.676E8 7.58 7.64 2 4 380.48 7.64 2 4 550 61.1 4.60 HVO_A0150 TrmB family transcription regulator 7.63 1 2 2 4 1.950E8 0.00 7.63 2 2 85.05 7.63 2 2 354 39.0 4.63 HVO_1821 GNAT family acetyltransferase Pat2 7.61 1 2 2 4 9.404E7 0.00 7.61 2 2 135.69 7.61 2 2 184 20.4 4.30 HVO_0469 AstE family protein 7.55 1 2 2 6 2.094E8 2.45 7.55 2 3 262.91 7.55 2 3 318 33.9 5.85 HVO_A0586 sugar nucleotidyltransferase 7.54 1 2 2 3 1.617E8 300.74 7.54 2 3 411 43.7 4.69 HVO_2503 kynureninase 7.53 1 3 3 5 5.380E7 519.84 7.53 3 5 425 46.0 4.54 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 7.43 1 2 2 7 1.389E8 1.76 7.43 2 3 222.13 7.43 2 4 377 39.2 4.18 HVO_2427 replication factor C large subunit 7.38 1 3 3 7 5.135E7 5.75 7.38 3 3 383.52 7.38 3 4 488 53.4 4.67 HVO_1579 uridine phosphorylase 7.35 1 2 2 3 2.071E8 136.70 7.35 2 3 272 29.0 4.64 HVO_2759 peptidase M42 family protein 7.34 1 2 2 3 4.662E8 2.16 7.34 2 3 354 37.0 4.40 HVO_A0331 D-galactonate dehydratase 7.29 1 2 2 4 1.215E8 2.42 7.29 2 2 152.89 7.29 2 2 384 42.8 4.83 HVO_1895 KEOPS complex subunit Kae1/Bud32 7.25 1 2 2 8 9.526E7 8.73 7.25 2 4 529.44 7.25 2 4 552 59.0 5.07 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 7.19 1 0 4 17 2.732E8 8.61 7.19 4 8 1095.57 7.19 4 9 473 51.2 5.05 HVO_1375 O-succinylbenzoic acid--CoA ligase 7.17 1 3 3 8 5.446E7 5.30 7.17 3 4 385.29 7.17 3 4 614 64.7 4.28 HVO_2380 AAA-type ATPase (CDC48 subfamily) 7.13 1 4 4 10 1.112E8 2.45 4.17 3 4 387.38 7.13 4 6 743 81.9 4.82 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 7.12 1 2 2 2 7.738E7 189.66 7.12 2 2 323 34.9 5.24 HVO_2575 homolog to translation elongation factor aEF-1 alpha subunit 7.12 1 2 2 2 6.777E7 64.52 7.12 2 2 534 57.8 4.81 HVO_2761 mevalonate kinase 7.08 1 2 2 6 8.849E7 3.55 7.08 2 3 242.46 7.08 2 3 367 38.2 4.31 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 6 1.100E8 4.62 7.07 2 3 368.23 7.07 2 3 297 32.3 3.98 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 7.03 1 4 4 11 5.107E8 9.24 5.56 3 5 671.73 7.03 4 6 612 67.3 4.16 HVO_2880 probable peptide chain release factor pelota 7.02 1 2 2 4 1.524E8 2.82 7.02 2 2 231.19 7.02 2 2 356 39.3 4.63 HVO_2772 rhodanese domain protein / probable metallo-beta-lactamase family hydrolase 6.99 1 2 2 6 3.055E7 4.67 6.99 2 3 299.18 6.99 2 3 386 41.3 4.46 HVO_0552 DNA mismatch repair protein MutS 6.93 1 5 5 14 2.568E8 6.91 6.93 5 7 767.91 6.93 5 7 924 99.2 4.65 HVO_A0547 DUF1028 family protein 6.91 1 2 2 7 8.173E7 2.66 6.91 2 3 349.51 6.91 2 4 333 35.2 4.16 HVO_1867 lysine--tRNA ligase 6.85 1 4 4 7 2.764E8 1.95 5.23 3 3 287.87 6.85 4 4 555 62.1 4.46 HVO_0724 ArsA family ATPase 6.85 1 2 2 3 2.517E7 206.90 6.85 2 3 409 43.9 4.22 HVO_0854 DNA double-strand break repair ATPase Rad50 6.83 1 4 4 12 4.251E7 4.13 6.83 4 6 457.84 6.83 4 6 893 100.0 4.58 HVO_0760 "probable glycosyltransferase, type 2" 6.79 1 2 2 4 5.442E7 0.00 6.79 2 2 72.14 6.79 2 2 368 40.7 4.82 HVO_2071 conserved hypothetical protein 6.74 1 3 3 5 6.569E7 5.16 6.74 3 3 245.23 4.92 2 2 549 58.4 4.72 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 6.73 1 2 2 7 9.837E7 0.00 6.73 2 4 126.48 6.73 2 3 401 43.1 4.60 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 6.67 1 2 2 10 6.515E7 10.76 6.67 2 5 644.49 6.67 2 5 360 39.5 4.31 HVO_C0042 helicase domain protein 6.67 1 7 7 23 1.759E8 14.46 6.67 7 12 960.36 6.67 7 11 1274 144.4 4.67 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 6.65 1 2 2 4 2.646E7 1.84 6.65 2 2 156.43 6.65 2 2 406 43.1 4.60 HVO_C0001 Orc1-type DNA replication protein 6.62 1 3 3 10 6.272E7 2.27 6.62 3 5 445.62 6.62 3 5 408 45.2 4.97 HVO_0069 sulfatase 6.60 1 2 3 5 4.822E7 3.84 6.60 3 3 164.58 4.08 2 2 515 57.4 4.35 HVO_0968 NADH dehydrogenase-like complex subunit CD 6.56 1 0 4 11 2.122E8 4.49 6.21 3 5 444.98 6.56 4 6 564 63.3 4.60 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 6.53 1 2 2 4 3.424E7 2.39 6.53 2 2 162.98 6.53 2 2 475 49.3 4.49 HVO_2350 YyaL family protein 6.52 1 2 2 8 1.128E8 6.97 6.52 2 4 377.41 6.52 2 4 552 58.8 4.59 HVO_2697 DNA primase small subunit 6.49 1 2 2 2 2.017E7 123.76 6.49 2 2 385 42.6 4.72 HVO_0662 HTH domain protein / thiamine-phosphate synthase 6.35 1 2 2 6 5.138E7 3.66 6.35 2 3 293.44 6.35 2 3 299 31.9 4.44 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 6.35 1 4 4 7 8.443E7 5.78 6.35 4 4 140.49 3.78 2 3 740 85.6 4.70 HVO_2580 L-aspartate oxidase 6.33 1 3 3 5 8.249E7 2.71 5.21 2 2 189.60 6.33 3 3 537 55.8 4.63 HVO_0896 acyl-CoA synthetase 6.30 1 3 3 3 3.024E7 4.46 6.30 3 3 540 59.8 4.56 HVO_0733 transcription initiation factor TFB 6.13 1 0 2 6 5.428E8 7.47 6.13 2 3 541.43 6.13 2 3 326 37.2 6.00 HVO_1340 "probable glycosyltransferase, type 1" 6.13 1 2 2 4 1.753E8 0.00 6.13 2 2 182.74 6.13 2 2 375 41.0 4.42 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 6.12 1 2 2 3 9.742E7 227.00 6.12 2 3 327 36.0 4.73 HVO_1058 TrkA domain protein 6.07 1 2 2 8 1.432E8 8.95 6.07 2 4 471.47 6.07 2 4 445 47.7 4.35 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 6.03 1 0 4 15 1.351E8 11.42 6.03 4 8 814.87 3.90 3 7 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 6.03 1 0 4 15 1.351E8 11.42 6.03 4 8 814.87 3.90 3 7 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 6.03 1 0 4 15 1.351E8 11.42 6.03 4 8 814.87 3.90 3 7 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 6.03 1 0 4 15 1.351E8 11.42 6.03 4 8 814.87 3.90 3 7 564 60.0 7.72 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 6.01 1 2 2 6 1.014E7 2.24 6.01 2 3 228.10 6.01 2 3 383 42.0 4.49 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 5.95 1 2 2 6 1.635E8 5.88 5.95 2 3 310.29 5.95 2 3 353 36.7 4.65 HVO_2510 GNAT family acetyltransferase 5.92 1 2 2 2 1.261E8 170.34 5.92 2 2 304 33.7 4.49 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 5.81 1 2 2 5 6.458E7 1.97 5.81 2 3 157.40 5.81 2 2 327 36.2 4.63 HVO_2908 dihydropteroate synthase 5.80 1 2 2 3 3.561E7 202.83 5.80 2 3 379 40.8 4.53 HVO_0710 aminodeoxychorismate synthase component II 5.75 1 2 2 4 1.151E8 0.00 5.75 2 2 93.43 5.75 2 2 504 54.6 4.53 HVO_3000 DNA ligase (NAD) 5.72 1 3 3 8 5.067E8 8.44 5.72 3 4 435.76 5.72 3 4 699 75.8 4.50 HVO_0014 ATP-dependent DNA helicase Hel308a 5.68 1 4 4 8 8.039E7 0.00 4.72 3 4 288.59 4.47 3 4 827 90.3 4.67 HVO_1357 receiver/bat box HTH-10 family transcription regulator 5.67 1 2 2 4 1.185E8 2.47 5.67 2 2 147.48 5.67 2 2 582 62.7 4.40 HVO_1140 acyl-CoA dehydrogenase 5.53 1 2 2 8 2.133E8 6.75 5.53 2 4 461.12 5.53 2 4 380 41.2 4.55 HVO_1711 glucoamylase 5.49 1 7 7 18 2.048E8 11.03 5.49 7 9 853.15 4.83 6 9 1511 166.1 4.64 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 5.48 1 0 3 8 3.018E8 2.55 5.48 3 4 445.16 5.48 3 4 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 5.48 1 0 3 8 3.018E8 2.55 5.48 3 4 445.16 5.48 3 4 456 49.2 4.77 HVO_1113 "FtsZ family protein, type III" 5.40 1 0 2 10 8.216E8 7.32 5.40 2 5 491.53 5.40 2 5 389 40.8 4.89 HVO_1710 alpha amylase 5.32 1 3 4 9 1.620E8 2.17 3.25 2 3 412.92 5.32 4 6 677 75.0 4.45 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 5.02 1 3 3 7 9.039E7 0.00 3.19 2 3 235.84 5.02 3 4 658 72.1 4.70 HVO_0911 GTP-binding protein Drg 4.88 1 2 2 5 9.616E7 0.00 4.88 2 2 190.08 4.88 2 3 369 40.5 4.81 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 4.82 1 3 3 8 7.767E7 8.29 4.82 3 4 449.34 4.82 3 4 706 73.3 4.39 27894337 keratin 20 [Homo sapiens] 4.72 1 1 2 4 2.522E7 2.55 4.72 2 2 204.80 4.72 2 2 424 48.5 5.69 HVO_1683 4-alpha-glucanotransferase 4.64 1 2 2 4 9.760E7 0.00 4.64 2 2 107.55 4.64 2 2 496 56.3 4.45 HVO_A0158 acyl-CoA synthetase 4.62 1 0 3 20 1.103E9 11.14 4.62 3 10 1168.80 4.62 3 10 650 71.2 4.63 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 4.34 1 5 5 12 1.313E8 1.69 3.00 4 5 465.06 4.34 5 7 1335 150.5 4.60 386849 keratin type II 4.26 1 0 2 2 1.769E8 2.14 4.26 2 2 563 59.9 7.94 HVO_A0257 Orc1-type DNA replication protein 4.24 1 2 2 2 2.904E7 124.41 4.24 2 2 425 48.0 4.94 HVO_1979 tRNA pseudouridine synthase Pus10 4.22 1 2 2 2 2.281E8 2.15 4.22 2 2 427 46.9 4.39 HVO_2004 serine O-acetyltransferase 4.18 1 1 2 4 2.915E8 0.00 4.18 2 2 122.38 4.18 2 2 287 31.9 5.21 HVO_1629 conserved hypothetical protein 4.14 1 2 2 5 4.567E8 1.70 4.14 2 3 128.88 4.14 2 2 531 56.3 4.69 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 4.05 1 1 2 2 9.732E8 0.00 4.05 2 2 444 47.1 4.77 HVO_1625 conserved hypothetical protein 3.98 1 2 2 8 1.844E8 9.17 3.98 2 4 474.39 3.98 2 4 654 70.1 4.04 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 3.94 1 2 2 6 6.076E7 0.00 3.94 2 3 169.57 3.94 2 3 584 63.3 4.79 HVO_B0143 receiver/sensor box histidine kinase 3.85 1 2 2 8 1.273E8 1.96 3.85 2 4 203.48 3.85 2 4 597 66.0 4.41 4557890 keratin 5 [Homo sapiens] 3.73 1 0 3 13 1.153E8 9.28 3.73 3 7 761.33 1.69 2 6 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 3.73 1 0 3 13 1.153E8 9.28 3.73 3 7 761.33 1.69 2 6 590 62.4 8.06 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 3.50 1 0 2 6 5.943E8 0.00 3.50 2 3 280.71 3.50 2 3 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 3.50 1 0 2 6 5.943E8 0.00 3.50 2 3 280.71 3.50 2 3 400 44.1 5.14 31074631 keratin 1b [Homo sapiens] 3.46 1 0 2 14 7.044E8 11.42 3.46 2 7 1096.18 3.46 2 7 578 61.8 5.97 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 13 2.160E8 6.06 3.45 2 6 817.90 3.45 2 7 464 50.6 5.47 HVO_2883 conserved hypothetical protein 2.85 1 2 2 3 1.303E8 0.00 2.85 2 3 702 78.9 4.48 HVO_B0154 receiver/sensor box histidine kinase 2.69 1 2 2 3 1.578E7 3.47 2.69 2 3 1301 144.1 4.39 HVO_C0043 conserved hypothetical protein 2.57 1 2 2 2 5.737E7 1.69 2.57 2 2 661 73.8 4.75 HVO_0689 chromosome segregation protein Smc 2.42 1 2 2 6 4.531E7 0.00 2.42 2 3 225.14 2.42 2 3 1240 138.1 4.39 4504919 keratin 8 [Homo sapiens] 2.07 1 0 2 12 5.069E7 9.28 2.07 2 6 761.33 2.07 2 6 483 53.7 5.59