Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0433 F420H2:NADP oxidoreductase 86.94 1 11 11 62 3.345E9 66.76 86.94 11 31 3464.37 86.94 11 31 222 23.3 4.72 HVO_0359 translation elongation factor aEF-1 alpha subunit 79.33 1 19 23 803 6.136E10 755.37 75.06 22 371 61603.40 77.43 21 432 421 45.7 4.73 HVO_0356 translation elongation factor aEF-2 70.29 1 42 42 563 1.800E10 508.29 68.23 40 280 31887.70 70.29 41 283 727 80.4 4.73 HVO_2413 translation elongation factor aEF-1 alpha subunit 67.38 1 16 20 247 9.654E9 161.66 63.10 19 123 12599.30 65.48 19 124 420 45.6 4.75 HVO_2862 serine hydroxymethyltransferase 67.23 1 17 17 198 6.951E9 181.72 67.23 17 101 13083.93 67.23 17 97 415 44.3 4.53 HVO_1921 serine--tRNA ligase 66.74 1 24 24 116 3.049E9 90.47 58.70 23 59 6484.59 66.74 24 57 460 52.0 4.46 HVO_0729 inorganic pyrophosphatase 66.67 1 9 9 68 2.784E9 71.11 52.54 8 34 4525.14 51.98 8 34 177 20.4 4.16 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 64.57 1 15 15 196 9.275E9 180.27 62.86 14 97 13009.80 64.57 15 99 350 37.6 4.54 HVO_2900 fumarate hydratase 63.11 1 18 18 180 7.884E9 183.81 62.05 17 89 10983.62 53.52 16 91 469 50.1 4.78 HVO_0025 thiosulfate sulfurtransferase 61.89 1 11 11 178 1.440E10 140.91 59.44 10 91 10270.40 61.89 11 87 286 32.1 4.28 HVO_0677 aspartate--tRNA ligase 61.75 1 18 18 248 8.840E9 209.48 60.60 17 125 13936.77 61.75 18 123 434 48.7 4.50 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 61.34 1 7 7 97 5.312E9 89.55 50.52 6 37 9013.26 61.34 7 60 194 20.7 4.12 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 60.89 1 16 16 161 1.303E10 112.24 58.27 15 81 8462.62 60.89 16 80 381 41.0 4.23 HVO_A0207 CRISPR-associated protein Cas7 60.00 1 12 12 94 2.668E9 93.65 60.00 12 46 6262.96 60.00 12 48 340 38.2 4.54 HVO_0175 DNA polymerase sliding clamp 59.11 1 9 9 149 7.359E9 108.68 44.94 8 76 7359.74 59.11 9 73 247 26.7 4.39 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 58.97 1 11 11 182 9.136E9 131.47 58.97 11 92 9766.27 58.97 11 90 312 34.5 4.98 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 57.96 1 11 11 69 2.169E9 68.12 55.31 10 34 4642.87 57.96 11 35 226 25.5 4.25 HVO_2913 superoxide dismutase (Mn) 57.79 1 0 5 60 1.322E10 81.06 57.79 5 31 4817.10 57.79 5 29 199 22.3 4.48 HVO_0880 conserved hypothetical protein 57.65 1 16 16 101 9.396E8 96.40 57.65 16 50 6279.85 57.65 16 51 307 36.3 4.74 HVO_A0475 superoxide dismutase (Mn) 57.50 1 0 5 60 1.322E10 81.06 57.50 5 31 4817.10 57.50 5 29 200 22.4 4.45 HVO_1273 inosine-5'-monophosphate dehydrogenase 57.43 1 17 17 138 2.988E9 97.44 54.82 16 69 7954.09 57.43 17 69 498 53.3 4.55 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 56.77 1 15 15 154 8.671E9 147.65 56.77 15 76 10856.89 56.77 15 78 384 41.4 4.41 HVO_0161 ATP phosphoribosyltransferase 56.58 1 13 13 56 1.225E9 45.13 56.58 13 27 3251.68 56.58 13 29 281 30.4 4.60 HVO_1189 aldehyde dehydrogenase 55.71 1 21 21 140 4.840E9 108.15 48.43 20 69 8293.10 50.00 19 71 508 56.1 4.59 HVO_0999 DRTGG domain protein 55.29 1 15 15 81 2.024E9 73.39 55.29 15 41 4644.89 52.91 14 40 378 39.8 4.44 HVO_2588 isocitrate dehydrogenase (NADP) 54.65 1 19 19 185 9.327E9 188.49 49.64 17 93 12853.40 52.98 18 92 419 45.8 4.59 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 54.48 1 5 5 22 5.618E8 18.96 47.76 4 9 1618.92 54.48 5 13 134 13.9 4.55 HVO_0989 conserved hypothetical protein 53.97 1 6 6 24 4.045E8 14.35 53.97 6 12 1221.84 53.97 6 12 126 14.4 4.81 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 53.52 1 12 12 78 3.379E9 57.51 53.52 12 41 4126.15 53.52 12 37 355 38.2 4.68 HVO_0329 branched-chain amino acid aminotransferase 52.88 1 15 15 135 5.175E9 124.14 52.88 15 69 8101.32 52.88 15 66 312 35.0 4.58 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 52.67 1 10 10 54 2.084E9 52.60 52.67 10 27 3081.73 52.67 10 27 281 30.6 4.59 HVO_1145 30S ribosomal protein S1e 52.27 1 11 11 57 2.471E9 61.95 49.55 10 29 4186.87 52.27 11 28 220 24.8 4.86 HVO_2015 conserved hypothetical protein 52.17 1 13 13 300 3.509E10 329.57 52.17 13 153 22120.51 52.17 12 147 345 37.7 4.25 HVO_2849 probable PrkA-type serine/threonine protein kinase 52.17 1 27 28 122 2.654E9 80.96 46.81 26 57 7245.06 52.17 28 65 690 79.9 4.79 HVO_0859 FeS assembly ATPase SufC 52.16 1 14 14 109 4.064E9 83.53 50.17 13 55 6289.69 40.86 13 54 301 33.4 4.35 HVO_0239 glutamine synthetase 51.54 1 19 20 200 1.273E10 148.75 51.54 20 100 11163.76 51.54 19 100 456 50.5 4.56 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 50.52 1 11 11 150 7.034E9 148.64 50.52 11 73 10091.12 48.43 10 77 287 31.0 4.73 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 25 1.831E9 6.71 37.91 4 12 1120.69 39.22 4 13 153 16.9 4.21 HVO_1133 conserved hypothetical protein 49.50 1 3 3 28 1.233E9 31.12 49.50 3 14 2104.10 49.50 3 14 101 11.7 4.58 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 49.46 1 7 7 46 2.236E9 45.47 44.02 6 22 3011.95 49.46 7 24 184 19.8 5.30 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 48.98 1 13 13 57 1.626E9 61.01 46.36 12 28 3921.24 48.98 13 29 343 38.4 4.94 HVO_0536 ferritin 48.30 1 4 4 33 1.226E9 37.82 48.30 4 16 1785.08 48.30 4 17 176 19.9 4.50 HVO_2534 UspA domain protein 48.12 1 2 2 2 1.457E8 0.00 48.12 2 2 133 14.3 4.58 HVO_1082 homolog to orotate phosphoribosyltransferase 48.10 1 8 8 47 1.789E9 38.17 45.24 7 23 2727.40 42.86 7 24 210 22.3 4.42 HVO_1132 adenylosuccinate synthase 48.08 1 20 20 201 5.468E9 136.69 44.92 19 99 10391.52 47.63 18 102 443 48.2 4.56 HVO_2969 threonine synthase 47.97 1 13 13 86 3.990E9 63.90 47.97 13 43 4655.44 47.97 13 43 419 44.4 4.49 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 47.26 1 14 14 86 1.739E9 47.78 47.26 14 42 4136.49 42.23 13 44 457 48.4 4.35 HVO_0055 CBS domain protein 47.18 1 9 9 68 2.395E9 58.54 47.18 9 33 4581.45 47.18 9 35 284 30.8 4.27 HVO_2558 30S ribosomal protein S3 47.04 1 13 13 139 5.115E9 118.20 41.12 11 67 9485.39 47.04 13 72 304 33.4 4.06 HVO_2961 dihydrolipoyl dehydrogenase 46.95 1 14 14 50 7.844E8 55.59 41.47 13 25 2872.74 45.26 13 25 475 49.9 4.41 HVO_2225 AstE family protein 46.92 1 9 9 45 2.124E9 39.98 46.92 9 23 2596.59 46.92 9 22 341 36.9 4.53 HVO_2783 30S ribosomal protein S4 46.86 1 9 9 56 2.770E9 45.24 46.86 9 28 3589.20 46.86 9 28 175 20.1 5.24 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 46.79 1 10 10 49 3.410E9 37.88 46.79 10 25 3187.67 46.79 9 24 280 30.1 4.44 HVO_0861 SufB domain protein 46.77 1 13 13 82 3.508E9 71.23 46.77 13 43 5430.47 46.77 13 39 402 44.7 4.23 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 152 5.507E9 149.61 43.25 7 73 10596.16 46.37 8 79 289 29.8 4.27 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 46.28 1 21 21 283 1.339E10 276.48 34.71 17 138 20027.46 44.53 19 145 631 68.4 4.49 HVO_0240 Lrp/AsnC family transcription regulator 46.05 1 5 6 30 2.460E9 15.58 40.79 5 14 1641.15 46.05 6 16 152 16.9 4.39 HVO_A0295 amidase (hydantoinase/carbamoylase family) 45.85 1 15 15 73 9.896E8 63.21 43.90 14 37 4520.30 45.85 15 36 410 45.0 4.30 HVO_0778 thermosome subunit 3 45.80 1 16 17 118 1.598E9 114.74 43.89 16 59 7342.42 45.80 17 59 524 55.2 4.59 HVO_0602 3-dehydroquinate dehydratase 45.75 1 8 8 22 4.628E8 12.42 45.75 8 12 957.17 45.75 8 10 247 27.3 4.51 HVO_0024 thiosulfate sulfurtransferase 45.74 1 8 8 32 1.202E9 18.49 37.98 6 13 1754.25 45.74 8 19 258 28.4 4.30 HVO_1332 conserved hypothetical protein 45.74 1 5 5 16 5.426E8 10.17 31.78 3 7 1201.94 29.46 4 9 129 14.9 4.16 HVO_1502 3-isopropylmalate dehydrogenase 45.68 1 11 11 47 2.088E9 42.36 37.96 10 23 3262.97 45.68 11 24 324 33.7 4.23 HVO_0860 SufB domain protein 45.59 1 16 17 110 3.515E9 86.71 40.55 15 53 6483.41 43.91 16 57 476 53.2 4.69 HVO_2968 phosphoglycerate dehydrogenase 45.52 1 17 17 172 7.799E9 184.60 43.43 16 87 12685.75 45.52 17 85 525 55.3 4.36 HVO_1955 aconitate hydratase 45.41 1 24 24 293 9.628E9 297.47 44.65 23 145 19439.34 44.50 23 148 654 70.4 4.45 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 45.39 1 21 21 305 9.968E9 260.64 40.78 19 153 18637.55 45.39 21 152 586 64.0 4.49 HVO_1300 triosephosphate isomerase 45.33 1 6 6 39 3.948E9 37.69 45.33 6 21 2864.58 45.33 6 18 214 21.3 4.26 HVO_2724 beta-lactamase domain protein 44.89 1 15 15 111 3.726E9 95.26 44.89 14 54 5754.39 44.89 15 57 450 50.1 5.40 HVO_0317 A-type ATP synthase subunit B 44.66 1 13 14 76 4.718E9 75.83 42.95 13 38 5707.39 43.16 13 38 468 51.9 4.25 HVO_0085 GlnK-type ammonia transport regulator 44.54 1 3 4 27 6.319E8 22.72 44.54 4 14 1540.75 44.54 4 13 119 12.5 4.97 HVO_2519 conserved hypothetical protein 44.50 1 12 12 37 1.107E9 31.19 39.79 11 18 2473.33 41.62 10 19 382 40.7 4.35 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 44.39 1 18 18 100 2.709E9 104.70 44.39 18 54 6275.77 38.78 16 46 624 67.6 4.27 HVO_1858 30S ribosomal protein S19e 44.37 1 4 4 8 3.125E7 1.65 26.49 2 3 313.72 44.37 4 5 151 16.7 4.84 HVO_2646 dihydroxy-acid dehydratase 44.35 1 16 16 125 3.797E9 119.12 44.35 16 64 7699.13 42.47 15 61 584 61.8 4.42 HVO_2040 NAD-dependent epimerase/dehydratase 44.12 1 6 11 56 2.871E9 43.69 44.12 11 28 3375.01 44.12 11 28 306 33.8 4.51 HVO_B0118 SMC-like protein Sph2 43.63 1 25 25 142 3.098E9 111.90 40.99 24 74 7478.16 42.08 22 68 644 73.8 4.41 HVO_0212 homolog to lactoylglutathione lyase 43.55 1 3 3 12 1.089E9 13.56 43.55 3 6 1062.55 43.55 3 6 124 13.5 4.13 HVO_0455 thermosome subunit 2 43.45 1 19 19 120 3.525E9 97.29 43.45 19 59 6746.44 40.39 18 61 557 59.3 4.37 HVO_1684 threonine--tRNA ligase 43.39 1 25 25 136 3.794E9 114.12 42.15 24 70 7784.95 43.39 24 66 643 73.4 4.45 HVO_1637 FKBP-type peptidylprolyl isomerase 43.14 1 9 9 59 4.556E9 50.87 32.68 7 25 3850.15 43.14 9 34 306 33.8 3.76 HVO_1973 conserved hypothetical protein 43.11 1 4 4 11 7.357E7 8.98 26.95 3 5 508.61 43.11 4 6 167 18.1 4.36 HVO_0829 peptidase S9 family protein 43.09 1 18 18 73 1.768E9 52.07 37.83 16 37 4086.07 37.34 17 36 608 67.4 4.54 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 43.03 1 10 10 75 1.876E9 75.91 43.03 10 38 4579.24 40.91 9 37 330 36.3 4.35 HVO_2706 translation initiation factor aIF-2B delta subunit 42.91 1 9 9 34 1.311E9 25.54 40.07 8 16 1739.54 42.91 9 18 282 30.7 4.42 HVO_1291 fumarylacetoacetase family protein 42.80 1 6 6 27 1.999E9 15.41 38.27 5 13 1253.02 42.80 6 14 243 26.3 4.55 HVO_1545 dihydroxyacetone kinase subunit DhaL 42.67 1 8 8 62 3.966E9 49.46 42.67 8 30 3880.45 42.67 8 32 232 24.8 4.48 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 42.57 1 7 7 23 3.973E8 20.20 42.57 7 12 1250.22 42.57 7 11 202 22.2 5.11 HVO_2336 pyridoxal biosynthesis lyase PdxS 42.38 1 8 8 65 9.479E8 51.79 38.74 7 30 4097.24 42.38 8 35 302 32.5 4.81 HVO_2487 aspartate-semialdehyde dehydrogenase 42.15 1 8 8 97 5.241E9 69.40 42.15 8 48 4580.32 42.15 8 49 344 36.6 4.41 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.11 1 9 9 55 1.303E9 43.34 42.11 9 26 3515.42 42.11 9 29 266 27.8 4.84 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 41.76 1 10 10 46 8.361E8 41.34 41.76 10 23 2803.04 41.76 10 23 340 38.8 4.58 HVO_2861 conserved hypothetical protein 41.45 1 9 9 63 2.327E9 60.51 41.45 9 31 3873.17 41.45 9 32 275 29.1 4.27 HVO_0806 pyruvate kinase 41.37 1 19 19 91 3.363E9 84.08 41.37 19 46 5391.21 39.66 17 45 585 62.0 4.54 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 41.31 1 12 12 92 3.465E9 60.02 37.45 11 40 5996.26 41.31 12 52 259 29.9 4.36 HVO_1481 UspA domain protein 41.10 1 5 5 54 4.798E9 59.01 41.10 5 27 3601.90 41.10 5 27 163 17.7 4.40 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 41.08 1 7 7 37 1.043E9 31.18 36.36 6 19 1570.92 28.62 6 18 297 31.3 4.36 HVO_0449 prephenate dehydratase 40.67 1 8 8 36 5.695E8 31.00 40.67 8 18 2138.67 40.67 8 18 268 28.7 4.64 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 40.56 1 7 7 27 6.230E8 24.07 40.56 7 14 1678.48 40.56 7 13 286 31.2 4.54 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 65 2.919E9 68.36 40.26 5 35 4741.22 40.26 5 30 154 17.5 4.50 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 40.18 1 8 8 29 2.928E8 23.95 33.63 7 14 1910.25 40.18 8 15 336 36.8 4.12 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 40.00 1 9 9 36 1.358E9 29.87 32.22 8 19 1875.19 40.00 9 17 360 39.6 4.39 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 24 1.144E9 13.37 40.00 4 12 985.85 40.00 4 12 130 14.1 4.79 HVO_0348 DNA-directed RNA polymerase subunit B' 39.74 1 17 17 93 1.481E9 83.51 39.74 17 49 5403.59 36.62 15 44 609 67.7 4.92 HVO_1091 proteasome alpha subunit 39.68 1 9 10 55 2.401E9 52.72 36.90 9 27 3794.59 39.68 10 28 252 27.6 4.56 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 39.67 1 10 10 60 3.033E9 56.71 34.75 9 28 3984.22 39.67 10 32 305 33.8 4.74 HVO_2384 CBS domain protein 39.47 1 13 13 102 4.675E9 75.85 37.89 12 51 5146.86 39.47 13 51 380 42.5 5.01 HVO_2191 formyltetrahydrofolate deformylase 39.45 1 9 9 25 1.412E9 20.07 39.45 9 13 1535.88 35.78 8 12 327 36.2 4.63 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 39.44 1 10 10 61 2.047E9 64.20 36.89 9 28 4192.94 39.44 10 33 431 46.1 4.48 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 39.36 1 5 5 25 6.528E8 15.35 39.36 5 13 999.10 39.36 5 12 188 20.5 4.60 HVO_1198 UspA domain protein 39.31 1 4 5 14 7.983E8 11.66 39.31 5 7 694.60 39.31 5 7 145 15.6 4.75 HVO_1031 thioredoxin-disulfide reductase 39.18 1 9 9 28 5.870E8 22.15 32.75 7 13 1441.31 39.18 9 15 342 37.4 4.46 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 39.07 1 19 19 60 1.193E9 68.01 34.39 17 31 4213.89 35.39 16 29 599 65.3 4.51 HVO_0889 FAD-dependent oxidoreductase 38.79 1 3 3 7 2.020E8 4.64 26.64 2 3 526.16 38.79 3 4 214 21.8 3.89 HVO_2643 NADPH:quinone reductase 38.73 1 11 11 57 1.396E9 38.99 35.55 9 27 3420.33 38.73 10 30 346 37.2 4.55 HVO_0313 A-type ATP synthase subunit E 38.66 1 5 5 18 1.549E8 15.62 31.44 4 8 976.28 38.66 5 10 194 22.0 4.31 HVO_2057 sugar nucleotidyltransferase 38.38 1 10 10 52 1.533E9 37.28 38.38 10 26 2329.33 38.38 10 26 357 37.8 4.44 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 38.34 1 6 6 16 2.087E8 11.29 24.11 4 6 998.07 38.34 6 10 253 26.0 4.60 HVO_2544 30S ribosomal protein S5 38.32 1 8 8 49 5.983E9 33.39 38.32 8 25 2573.71 38.32 8 24 214 23.3 9.29 HVO_2552 30S ribosomal protein S4e 38.06 1 6 6 78 1.045E10 59.09 38.06 6 38 4203.19 38.06 6 40 247 26.6 4.58 HVO_0133 thermosome subunit 1 38.04 1 13 14 68 2.669E9 66.60 38.04 14 34 4743.00 36.79 13 34 560 58.9 4.25 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.95 1 11 11 88 3.604E9 53.43 37.95 11 47 3865.65 37.95 10 41 332 34.8 4.22 HVO_0104 DNA repair and recombination protein RadA 37.90 1 10 10 62 2.678E9 46.31 32.65 9 30 4249.30 36.15 9 32 343 37.3 4.64 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 37.84 1 7 7 56 1.500E9 44.82 37.84 7 28 3182.98 37.84 7 28 259 28.0 4.50 HVO_1212 KaiC-type circadian regulator CirA 37.80 1 8 8 64 3.422E9 79.03 37.80 8 32 5498.19 37.80 8 32 246 27.5 4.45 HVO_2555 30S ribosomal protein S17 37.72 1 2 2 4 4.226E8 0.00 37.72 2 2 120.00 37.72 2 2 114 12.7 4.81 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 37.71 1 12 12 51 1.526E9 43.53 35.81 11 25 2920.17 37.71 12 26 525 56.4 4.40 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 37.70 1 7 7 25 5.562E8 14.29 37.70 7 13 1036.81 37.70 7 12 305 32.7 4.56 HVO_0347 DNA-directed RNA polymerase subunit B'' 37.62 1 18 18 93 1.120E9 61.46 37.62 18 46 4389.15 37.62 18 47 521 58.9 5.00 HVO_0401 UspA domain protein 37.50 1 4 4 34 1.594E9 32.80 37.50 4 16 1930.18 37.50 4 18 152 16.4 4.79 HVO_A0307 Lrp/AsnC family transcription regulator 37.29 1 6 6 17 2.041E8 10.33 32.77 5 8 957.15 37.29 6 9 177 19.4 4.39 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 37.05 1 8 8 64 4.726E9 40.83 37.05 8 31 3888.25 37.05 8 33 413 45.8 4.45 HVO_1164 HD family hydrolase 37.04 1 9 9 33 8.657E8 10.84 37.04 9 18 1415.86 37.04 9 15 270 29.8 4.87 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 37.01 1 10 10 65 4.751E9 59.23 37.01 10 34 3725.73 35.40 9 31 435 46.9 4.63 HVO_0894 acyl-CoA synthetase 37.01 1 8 17 98 1.899E9 53.05 35.50 16 48 4581.63 35.95 16 50 662 74.3 4.48 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 36.84 1 5 5 28 1.433E9 20.74 36.84 5 14 1313.86 36.84 5 14 190 20.6 4.30 HVO_1541 glycerol kinase 36.67 1 13 13 84 2.553E9 56.83 33.33 12 39 5685.62 36.67 13 45 510 56.7 4.50 HVO_1134 conserved hypothetical protein 36.59 1 18 18 92 1.037E9 63.51 36.59 18 46 4871.97 33.42 16 46 757 80.6 4.35 HVO_A0496 UspA domain protein 36.55 1 9 9 37 1.324E9 31.56 36.55 9 19 1947.44 36.55 9 18 290 31.4 4.60 HVO_3007 malate dehydrogenase 36.51 1 10 10 174 8.716E9 156.98 36.51 10 88 8753.86 36.51 10 86 304 32.6 4.40 HVO_0870 proline--tRNA ligase 36.48 1 12 12 71 1.793E9 58.49 34.02 11 34 4321.56 36.48 12 37 488 54.9 4.44 HVO_0324 arginine--tRNA ligase 36.46 1 18 18 77 2.077E9 62.76 36.46 18 39 4329.95 33.73 17 38 587 65.0 4.35 HVO_A0206 CRISPR-associated protein Cas8b 36.40 1 19 19 93 1.887E9 65.29 36.40 19 48 5034.61 31.66 16 45 717 79.3 4.60 HVO_2774 enolase 36.34 1 9 9 59 3.145E9 44.81 36.34 9 30 3463.04 36.34 9 29 399 42.0 4.37 HVO_0869 glutamate synthase large subunit 36.33 1 38 38 153 1.340E9 131.01 36.33 38 79 8877.65 34.61 36 74 1511 163.8 4.70 HVO_2981 uracil phosphoribosyltransferase 36.28 1 5 5 12 9.276E8 4.64 24.34 3 4 678.82 36.28 5 8 226 24.5 4.49 HVO_1172 NAD-dependent epimerase/dehydratase 35.87 1 9 9 42 3.204E9 32.75 33.33 8 21 2409.81 35.87 9 21 315 34.9 4.34 HVO_2889 RecJ domain protein 35.80 1 19 19 105 3.837E9 99.86 33.47 18 52 6413.34 34.71 18 53 729 79.1 4.37 HVO_1854 histidine--tRNA ligase 35.73 1 11 11 48 1.358E9 41.59 35.73 11 24 2720.44 33.41 10 24 431 47.1 4.37 HVO_A0205 CRISPR-associated endoribonuclease Cas6 35.66 1 9 9 55 1.110E9 41.46 35.66 9 27 3361.27 35.66 9 28 272 31.0 5.44 HVO_1878 NAD synthase 35.51 1 8 8 51 3.151E9 36.34 26.45 7 24 2803.60 35.51 8 27 276 29.6 4.37 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 35.28 1 12 12 52 1.404E9 40.47 32.06 11 25 2672.13 35.28 12 27 496 55.0 4.53 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 35.16 1 9 9 49 1.103E9 49.55 35.16 9 25 3263.61 35.16 9 24 364 39.3 4.35 HVO_1076 sugar nucleotidyltransferase 35.09 1 7 7 47 3.061E9 55.08 35.09 7 24 3606.34 35.09 7 23 322 35.8 4.20 HVO_1593 PAC2 family protein 35.08 1 4 4 21 8.161E8 7.04 35.08 4 10 721.28 35.08 4 11 248 26.6 4.46 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 34.95 1 31 31 149 1.837E9 102.80 34.17 30 74 7426.66 34.95 31 75 1033 114.3 4.45 HVO_2879 ornithine cyclodeaminase 34.94 1 8 8 27 1.353E9 14.77 27.41 7 12 1309.25 32.23 7 15 332 34.6 4.45 HVO_1590 DnaK-type molecular chaperone Hsp70 34.88 1 20 20 136 5.656E9 128.73 33.92 19 68 8985.25 33.92 19 68 625 67.2 4.18 HVO_1454 aspartate carbamoyltransferase catalytic subunit 34.87 1 6 6 17 2.457E8 4.53 34.87 6 9 422.65 34.87 6 8 304 33.7 4.92 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 34.82 1 10 10 28 9.449E8 22.07 34.82 10 15 1360.17 25.89 8 13 336 38.0 4.61 HVO_A0301 polysaccharide deacetylase family protein 34.78 1 9 9 70 2.721E9 61.81 34.78 9 34 4178.59 34.78 9 36 299 34.2 4.56 HVO_2425 GNAT family acetyltransferase 34.72 1 6 6 31 2.201E9 23.45 34.72 6 16 1612.94 34.72 6 15 216 24.4 4.54 HVO_A0295_A luciferase family protein 34.67 1 9 9 32 5.266E8 26.51 34.67 9 16 1943.43 34.67 9 16 349 38.5 4.67 HVO_2813 RimK family protein 34.44 1 12 12 69 4.114E9 66.96 32.23 11 34 4424.85 34.44 12 35 453 49.0 4.73 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 34.38 1 9 9 52 1.342E9 53.45 34.38 9 26 3053.26 34.38 9 26 445 47.8 4.86 HVO_0809 methionine--tRNA ligase 34.32 1 18 18 86 1.502E9 72.64 31.22 16 41 5346.91 34.32 18 45 740 81.9 4.37 HVO_0792 3-dehydroquinate synthase type II 34.18 1 10 10 46 1.245E9 39.98 34.18 10 23 2576.23 34.18 10 23 392 43.1 4.44 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 34.18 1 12 12 60 1.316E9 47.22 34.18 12 32 3008.10 34.18 12 28 471 51.0 4.48 HVO_0122 phosphoglycerate dehydrogenase 33.95 1 7 7 23 7.591E8 16.40 26.85 6 10 1551.18 33.95 7 13 324 35.3 5.35 HVO_1391 NUDIX family hydrolase 33.77 1 4 4 20 1.545E8 14.86 33.77 4 10 1266.90 33.77 4 10 151 17.4 5.01 HVO_1338 replication protein A 33.72 1 9 9 30 7.176E8 20.01 33.72 9 16 1523.35 32.08 8 14 427 46.0 4.36 HVO_0743 probable phosphodiesterase 33.63 1 17 17 85 1.920E9 66.40 33.63 17 42 4611.18 33.63 17 43 449 50.5 4.56 HVO_1344 SBDS family protein 33.61 1 5 5 13 2.258E8 1.65 33.61 5 7 343.42 33.61 5 6 238 26.5 4.51 HVO_0316 A-type ATP synthase subunit A 33.45 1 15 15 83 2.626E9 69.62 32.08 14 41 4879.35 33.45 15 42 586 64.5 4.25 HVO_1506 ketol-acid reductoisomerase 33.33 1 7 7 35 5.599E8 38.78 33.33 7 17 2647.93 33.33 7 18 348 37.9 4.34 HVO_2204 "FtsZ family protein, type III" 32.91 1 8 10 44 1.760E9 38.85 32.91 10 21 2574.16 32.91 10 23 395 42.0 4.68 HVO_A0418 conserved hypothetical protein 32.90 1 4 4 13 1.399E8 9.65 32.90 4 6 566.27 32.90 4 7 155 17.9 4.67 HVO_1901 translation initiation factor aIF-2 gamma subunit 32.85 1 11 11 68 2.550E9 42.93 32.85 10 33 3326.00 32.85 11 35 411 43.9 4.36 HVO_A0388 Lrp/AsnC family transcription regulator 32.76 1 5 5 10 2.110E8 2.41 27.59 4 5 287.76 32.76 5 5 174 20.1 4.86 HVO_0980 NADH dehydrogenase-like complex subunit CD 32.68 1 9 13 44 7.953E8 23.31 32.68 13 22 1852.65 32.68 13 22 557 63.4 4.53 HVO_2468 probable oxidoreductase (short-chain dehydrogenase family) 32.34 1 6 6 24 2.605E8 23.70 32.34 6 12 1438.40 32.34 6 12 235 24.9 4.35 HVO_0017 conserved hypothetical protein 32.29 1 3 3 18 1.175E9 13.02 32.29 3 9 1226.79 32.29 3 9 192 21.9 4.50 HVO_2675 histidinol dehydrogenase 32.24 1 7 7 29 4.091E8 30.11 27.80 6 14 1872.10 32.24 7 15 428 45.4 4.50 HVO_0937 FMN-binding domain protein 32.19 1 3 3 12 2.118E8 9.88 32.19 3 6 715.30 32.19 3 6 146 16.2 4.36 HVO_2436 malic enzyme (NADP) 32.09 1 14 18 90 1.258E9 85.69 32.09 18 46 4951.81 30.76 17 44 751 81.4 4.55 HVO_0850 proteasome-activating nucleotidase 31.85 1 9 9 30 5.057E8 23.73 20.25 7 14 1788.40 29.63 8 16 405 45.6 4.60 HVO_1577 conserved hypothetical protein 31.64 1 4 4 14 1.196E9 15.61 31.64 4 7 904.76 31.64 4 7 177 19.4 4.74 HVO_2059 NAD-dependent epimerase/dehydratase 31.61 1 6 6 32 1.609E9 21.14 31.61 6 17 1548.34 31.61 6 15 310 34.1 4.40 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 26 3.037E9 23.79 31.45 3 13 1736.49 31.45 3 13 124 14.2 5.22 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 31.42 1 13 13 64 2.358E9 50.37 31.42 13 31 4331.86 31.42 13 33 592 66.6 4.61 HVO_0581 "cell division protein FtsZ, type II" 31.00 1 8 8 37 8.216E8 40.18 31.00 8 19 2379.96 27.00 7 18 400 42.5 4.75 HVO_0353 30S ribosomal protein S12 30.99 1 6 6 24 5.875E8 20.48 30.99 6 13 1193.70 27.46 5 11 142 15.5 9.91 HVO_0717 "cell division protein FtsZ, type I" 30.87 1 10 10 67 3.137E9 58.80 30.87 10 34 4023.52 30.87 10 33 379 39.8 4.40 HVO_2419 hydroxymethylglutaryl-CoA synthase 30.79 1 10 10 29 1.263E9 20.55 30.79 10 14 1356.66 26.52 9 15 445 50.1 4.64 HVO_1576 NAD-dependent epimerase/dehydratase 30.72 1 4 9 34 1.367E9 25.09 30.72 9 17 1627.47 30.72 9 17 306 33.9 4.51 HVO_1306 chorismate synthase 30.65 1 7 7 39 2.967E8 39.04 30.65 7 20 1902.10 30.65 7 19 385 41.9 4.83 HVO_2435 peptidase M24 family protein 30.43 1 7 7 24 2.309E8 7.92 30.43 7 12 774.58 30.43 7 12 368 40.0 4.53 HVO_0480 phosphoglycerate kinase 30.42 1 10 10 46 1.513E9 48.48 30.42 10 23 3152.90 30.42 10 23 401 43.6 4.37 HVO_0350 DNA-directed RNA polymerase subunit A'' 30.31 1 10 10 46 1.829E9 45.54 28.88 9 23 2478.10 30.31 10 23 419 46.1 4.35 HVO_0874 beta-lactamase domain protein 30.31 1 16 16 75 2.378E9 65.06 30.31 16 37 5127.37 30.31 16 38 640 71.9 5.14 HVO_0314 A-type ATP synthase subunit C 30.17 1 8 8 30 2.873E8 23.94 27.87 7 15 1797.36 27.59 7 15 348 38.7 4.50 HVO_0400 conserved hypothetical protein 30.16 1 2 2 9 2.494E8 10.09 30.16 2 5 312.81 30.16 2 4 126 13.9 4.68 HVO_1550 acyl-CoA thioester hydrolase 30.00 1 3 3 11 2.326E8 4.73 30.00 3 5 486.08 30.00 3 6 160 17.6 4.55 HVO_1967 glucose-6-phosphate isomerase 30.00 1 8 8 33 6.632E8 9.87 30.00 8 17 1288.46 30.00 8 16 430 45.6 4.40 HVO_2347 conserved hypothetical protein 30.00 1 3 3 9 1.748E8 3.13 30.00 3 5 429.62 22.14 2 4 140 15.5 4.37 HVO_2773 30S ribosomal protein S2 30.00 1 4 4 40 3.748E9 48.60 30.00 4 19 3468.74 30.00 4 21 260 28.3 4.16 HVO_0167 adenosylhomocysteinase 29.67 1 8 8 30 1.052E9 17.98 25.47 7 13 2065.38 25.23 7 17 428 46.6 4.39 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 29.48 1 8 8 27 1.768E8 20.65 29.48 8 14 1431.11 27.27 7 13 363 39.3 4.97 HVO_1488 D-gluconate dehydratase 29.37 1 8 10 61 2.301E9 44.08 29.37 10 32 3116.55 29.37 10 29 412 45.8 4.60 HVO_0243 threonine aldolase 29.33 1 7 7 18 2.166E8 15.49 29.33 7 9 1086.87 27.86 6 9 341 35.6 4.55 HVO_1235 creatininase 29.17 1 5 5 24 3.076E8 12.34 23.86 4 12 1106.86 29.17 5 12 264 29.2 4.84 HVO_0388 homolog to ribonuclease R 29.16 1 11 11 39 1.925E8 39.07 29.16 10 20 2481.41 23.23 10 19 439 50.3 4.73 HVO_1778 catalase-peroxidase 29.11 1 14 14 75 2.593E9 70.31 29.11 14 37 4498.87 29.11 14 38 718 80.0 4.31 HVO_1727 TATA-binding transcription initiation factor 29.03 1 5 6 40 5.034E9 45.57 29.03 6 21 3270.08 29.03 6 19 186 19.9 4.36 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 28.96 1 3 3 12 3.860E8 4.22 13.66 2 6 680.08 28.96 3 6 183 20.0 4.21 HVO_A0303 probable allantoinase 28.76 1 8 8 39 1.366E9 47.33 28.76 8 19 2825.31 28.76 8 20 459 50.1 4.42 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 28.75 1 13 13 38 6.581E8 16.03 27.64 12 19 1664.81 28.75 13 19 626 67.6 4.65 HVO_B0066 Lrp/AsnC family transcription regulator 28.66 1 3 3 8 9.362E7 4.18 28.66 3 4 344.86 28.66 3 4 164 18.5 4.41 HVO_B0061 precorrin-2 C20-methyltransferase 28.51 1 5 5 20 6.158E8 15.32 28.51 5 10 1037.04 28.51 5 10 235 25.3 4.63 HVO_2912 ThiJ/PfpI domain protein 28.36 1 3 3 12 1.590E8 9.30 28.36 3 6 551.15 28.36 3 6 201 20.9 4.36 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 28.32 1 8 8 27 5.064E8 18.81 25.17 7 13 1198.24 24.48 7 14 286 30.8 4.46 HVO_0694 probable phosphoribosyltransferase 28.27 1 6 6 21 1.029E8 18.36 28.27 6 11 1059.80 28.27 6 10 237 27.0 4.32 HVO_2708 YfiH family protein 28.26 1 5 5 16 6.954E8 19.56 28.26 5 8 1225.82 28.26 5 8 322 35.4 4.35 HVO_0600 ACT domain protein 28.25 1 4 4 11 2.754E8 9.31 28.25 4 6 634.85 23.73 3 5 177 19.2 4.44 HVO_B0375 Spo0M family protein 28.16 1 4 4 12 2.289E8 14.12 28.16 4 7 646.94 21.63 3 5 245 27.2 4.35 HVO_0417 metal-dependent carboxypeptidase 28.09 1 13 13 51 1.051E9 40.31 28.09 13 25 2716.37 28.09 13 26 502 57.3 4.42 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 27.98 1 5 5 17 7.164E8 9.55 27.98 5 9 590.69 27.98 5 8 386 42.1 4.49 HVO_A0306 4-aminobutyrate aminotransferase 27.87 1 10 10 39 6.438E8 39.75 21.57 7 17 2873.51 27.87 10 22 445 47.6 4.68 HVO_0008 aspartate kinase 27.81 1 8 8 71 3.748E9 44.88 27.81 8 34 3359.49 27.81 8 37 392 41.7 4.46 HVO_A0156 acyl-CoA synthetase 27.71 1 4 13 68 1.899E9 39.59 26.66 12 33 3342.84 27.71 13 35 664 74.0 4.40 HVO_1504 3-isopropylmalate dehydratase large subunit 27.70 1 11 11 50 1.314E9 41.12 27.70 11 26 3145.51 21.56 9 24 473 51.6 4.55 HVO_1087 UspA domain protein 27.66 1 4 4 14 2.312E8 8.44 27.66 4 7 793.46 27.66 4 7 141 15.2 4.98 HVO_2013 "FtsZ family protein, type III" 27.66 1 5 5 22 2.158E8 18.46 26.14 4 10 1333.50 27.66 5 12 394 41.5 4.61 HVO_1932 2-D-hydroxyacid dehydrogenase 27.60 1 7 7 28 4.689E8 21.51 27.60 7 14 1339.74 27.60 7 14 308 33.0 4.60 HVO_1571 DNA topoisomerase VI subunit B 27.57 1 15 15 51 6.259E8 43.42 25.19 14 25 3054.60 24.94 13 26 798 87.4 4.73 HVO_0407 conserved hypothetical protein 27.42 1 3 3 8 2.900E8 8.41 27.42 3 4 430.69 27.42 3 4 124 13.4 4.44 HVO_0549 2-keto-3-deoxygluconate kinase 27.19 1 9 9 26 4.458E8 14.37 23.44 8 13 1308.87 27.19 8 13 320 34.1 4.34 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 27.07 1 8 8 35 7.920E8 21.61 19.02 7 18 2149.04 27.07 8 17 447 48.5 4.56 HVO_1871 UPF0447 family protein 26.95 1 9 9 42 8.898E8 22.04 21.36 7 19 1884.05 26.95 9 23 501 56.1 4.59 HVO_0573 endonuclease IV 26.80 1 5 5 20 5.449E8 10.97 26.80 5 10 903.20 26.80 5 10 291 31.4 4.44 HVO_1175 DUF2110 family protein 26.67 1 4 4 24 1.022E9 24.68 26.67 4 12 1461.88 26.67 4 12 225 24.4 4.63 HVO_2496 adenylate kinase 26.44 1 5 5 34 3.212E9 31.75 26.44 5 18 2200.93 26.44 5 16 208 23.1 4.25 HVO_1287 PfpI family protease 26.26 1 4 4 14 7.057E8 3.65 26.26 4 6 540.96 26.26 4 8 198 21.5 4.53 HVO_1989 tRNA (pseudouridine(54)-N(1))-methyltransferase 26.26 1 2 2 7 1.692E8 0.00 26.26 2 4 177.16 26.26 2 3 198 21.9 4.79 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 18 4.978E8 16.88 26.15 3 9 1104.48 26.15 3 9 130 13.4 8.56 HVO_0203 replication factor C small subunit 25.99 1 6 6 24 3.907E8 21.27 25.99 6 11 1402.71 25.99 6 13 327 36.2 4.51 HVO_A0636 YbaK domain protein 25.95 1 3 3 15 4.037E7 17.42 25.95 3 8 768.36 25.95 3 7 158 16.7 4.54 HVO_1527 glucose-1-phosphate uridylyltransferase 25.93 1 6 6 23 3.908E8 16.02 23.46 5 10 1286.48 25.93 6 13 243 27.5 4.70 HVO_0466 citrate (si)-synthase 25.86 1 8 8 64 2.220E9 69.45 25.86 8 34 4090.98 25.86 8 30 379 41.8 4.55 HVO_2777 30S ribosomal protein S9 25.76 1 4 4 10 1.035E8 5.43 25.76 4 5 509.00 25.76 4 5 132 14.7 9.74 HVO_0087 porphobilinogen synthase 25.69 1 6 6 16 5.270E8 10.17 12.84 4 7 799.67 25.69 6 9 327 35.3 4.72 HVO_1824 conserved hypothetical protein 25.64 1 8 8 26 5.158E8 16.32 25.64 8 13 870.51 25.64 8 13 429 47.4 4.20 HVO_A0012 hypothetical protein 25.50 1 3 3 18 3.507E8 6.87 16.11 2 8 912.55 25.50 3 10 149 17.7 4.54 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 25.41 1 9 9 47 2.285E9 28.30 25.41 9 24 2167.62 25.41 9 23 370 41.9 4.48 HVO_0424 ABC-type transport system ATP-binding protein 25.33 1 12 12 35 3.297E8 29.28 25.33 12 18 1803.87 23.84 11 17 604 67.2 4.49 HVO_0214 L-lactate dehydrogenase 25.31 1 9 9 49 3.309E9 42.91 25.31 9 24 3261.20 23.44 8 25 320 34.5 4.49 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 25.29 1 8 8 30 4.856E8 17.02 25.29 8 15 1326.67 25.29 8 15 348 38.2 4.32 HVO_2621 phosphoenolpyruvate carboxylase 25.20 1 17 17 69 1.242E9 51.56 22.52 16 35 3537.23 24.19 16 34 897 102.3 4.64 >sp|TRYP_PIG| 25.11 1 4 4 102 4.598E10 141.86 25.11 4 53 9056.91 25.11 4 49 231 24.4 7.18 HVO_2781 DNA-directed RNA polymerase subunit D 25.10 1 5 5 45 1.337E9 27.10 25.10 5 22 2402.59 25.10 5 23 259 28.1 4.32 HVO_B0018 ParA domain protein 25.09 1 3 3 8 1.490E8 6.30 25.09 3 4 483.74 25.09 3 4 287 31.7 4.74 HVO_0034 acyl-CoA thioester hydrolase 25.00 1 3 3 14 1.958E8 8.58 25.00 3 7 692.00 25.00 3 7 164 18.3 4.65 HVO_0134 KH domain protein 25.00 1 3 3 6 1.072E8 4.49 25.00 3 3 230.24 25.00 3 3 180 19.9 4.94 HVO_0138 tyrosine--tRNA ligase 25.00 1 7 7 19 3.705E8 7.15 18.60 6 9 888.15 20.43 6 10 328 36.1 4.34 HVO_1581 cytidine deaminase 25.00 1 3 3 6 8.925E7 1.78 20.00 2 2 235.22 25.00 3 4 140 15.0 4.22 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 24.94 1 7 7 34 1.004E9 32.86 24.94 7 17 2331.99 24.94 7 17 453 47.5 4.63 HVO_2467 NADPH:quinone reductase 24.92 1 5 5 22 4.012E8 15.87 24.92 5 11 1078.42 24.92 5 11 321 33.0 4.51 HVO_1660 DisA-N domain protein 24.91 1 5 5 15 6.222E8 14.49 24.91 5 8 901.68 24.91 5 7 269 28.9 4.73 HVO_2790 ATP-binding protein Mrp 24.86 1 5 5 23 3.152E8 10.13 20.23 4 11 878.77 24.86 5 12 346 36.8 4.50 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 24.60 1 5 5 25 1.969E9 26.18 17.86 4 12 2162.72 24.60 5 13 252 26.0 4.39 HVO_1187 conserved hypothetical protein 24.48 1 3 3 5 1.009E8 0.00 24.48 3 3 119.83 17.48 2 2 143 16.4 4.86 HVO_2726 glutamate--tRNA ligase 24.44 1 11 11 37 6.882E8 23.70 24.44 11 21 1432.67 19.32 8 16 585 65.2 4.58 HVO_0788 tryptophan synthase beta subunit 24.41 1 7 7 17 4.113E8 16.00 22.51 6 9 994.19 13.98 5 8 422 45.7 4.65 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 24.33 1 10 10 46 4.903E8 37.09 22.17 9 22 2880.18 24.33 10 24 600 65.3 4.68 HVO_1370 gamma-glutamyl phosphate reductase 24.32 1 9 9 40 1.661E9 24.43 24.32 9 21 2019.95 22.97 8 19 444 48.1 4.34 HVO_1478 transcription initiation factor TFB 24.29 1 5 7 25 5.548E8 23.98 24.29 7 13 1443.11 21.77 6 12 317 35.7 5.47 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 24.18 1 3 3 15 3.242E8 2.68 24.18 3 7 582.77 24.18 3 8 91 10.4 4.07 HVO_2188 phosphoribosylformylglycinamidine synthase 1 24.11 1 4 4 18 2.433E8 9.89 24.11 4 9 801.24 24.11 4 9 224 23.9 4.36 HVO_2562 50S ribosomal protein L23 24.10 1 2 2 4 2.336E7 2.02 24.10 2 2 204.07 24.10 2 2 83 9.4 5.48 HVO_A0003 ParA domain protein 24.09 1 4 4 7 1.492E8 0.00 16.06 3 3 232.24 24.09 4 4 274 30.3 4.53 HVO_2624 CTP synthase 24.04 1 10 10 37 1.153E9 25.09 22.04 9 19 1754.17 24.04 10 18 549 60.8 4.70 HVO_0233 ribose-phosphate pyrophosphokinase 24.03 1 4 4 12 3.965E8 8.58 14.49 3 6 479.34 24.03 4 6 283 29.6 4.40 HVO_A0266 IclR family transcription regulator 23.92 1 5 5 13 1.253E8 14.46 23.92 5 7 743.16 23.92 5 6 255 27.7 6.05 HVO_B0084 conserved hypothetical protein 23.91 1 2 2 6 1.049E8 2.06 23.91 2 3 303.23 23.91 2 3 138 14.3 4.70 HVO_1562 proteasome beta subunit 23.87 1 3 3 15 4.307E8 10.71 23.87 3 8 935.19 23.87 3 7 243 26.0 4.63 HVO_1879 enoyl-CoA hydratase 23.81 1 4 4 8 1.572E9 3.60 23.81 4 5 271.84 8.23 2 3 231 24.3 5.21 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 23.79 1 4 4 14 5.340E8 5.14 23.79 4 7 679.13 23.79 4 7 269 28.3 4.49 HVO_2858 Lrp/AsnC family transcription regulator 23.72 1 5 5 14 1.062E8 4.74 23.72 5 7 565.07 23.72 5 7 156 17.6 4.61 HVO_2947 phenylalanine--tRNA ligase beta subunit 23.51 1 10 10 36 1.294E9 21.97 21.40 8 16 1981.87 23.51 10 20 570 63.3 4.46 HVO_1018 RecJ domain protein 23.38 1 13 13 45 8.199E8 29.65 23.38 13 23 2189.81 20.06 11 22 633 69.8 4.58 HVO_A0485 aminotransferase class V 23.36 1 6 6 25 5.239E8 27.10 23.36 6 13 1596.62 23.36 6 12 351 37.3 4.26 HVO_2923 proteasome alpha subunit 23.29 1 4 5 21 6.329E8 12.81 23.29 5 11 1008.26 23.29 5 10 249 26.7 4.39 HVO_1025 acetyl-CoA C-acyltransferase 23.24 1 6 6 15 4.763E8 12.36 23.24 6 8 896.46 20.37 5 7 383 40.7 4.56 HVO_1567 conserved hypothetical protein 22.98 1 4 4 15 5.689E8 8.37 22.98 4 8 731.70 22.98 4 7 235 25.7 4.36 HVO_1459 ThuA family protein 22.69 1 3 3 18 9.472E8 23.97 22.69 3 9 1400.53 22.69 3 9 238 26.8 4.67 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 22.69 1 7 7 36 1.611E9 28.88 22.69 7 18 1742.69 22.69 7 18 357 40.3 4.40 HVO_1690 DHH family phosphoesterase 22.68 1 7 7 34 1.005E8 38.92 20.00 6 17 2164.65 22.68 7 17 485 52.1 4.48 HVO_B0057 precorrin-3B C17-methyltransferase 22.67 1 4 4 15 5.409E8 17.15 22.67 4 8 1108.60 13.66 3 7 344 36.3 4.31 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 22.62 1 4 4 16 2.863E8 17.38 21.13 3 7 1137.43 22.62 4 9 336 36.0 4.51 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 22.59 1 4 4 13 2.710E8 14.11 22.59 4 7 880.68 22.59 4 6 270 29.1 4.35 HVO_2707 GFO family oxidoreductase 22.58 1 7 7 21 4.295E8 17.39 22.58 7 12 910.76 18.01 5 9 372 41.0 4.55 17318569 keratin 1 [Homo sapiens] 22.52 1 1 13 50 9.429E8 43.58 22.52 13 25 3292.77 22.52 13 25 644 66.0 8.12 HVO_0736 DUF302 family protein 22.52 1 3 3 5 1.270E8 1.92 22.52 3 3 136.09 11.92 2 2 151 16.4 4.30 HVO_1570 DNA topoisomerase VI subunit A 22.40 1 5 5 16 4.757E8 11.24 22.40 5 8 724.31 22.40 5 8 366 41.8 4.63 HVO_2688 TrmB family transcription regulator 22.38 1 7 7 35 1.403E9 34.34 22.38 7 18 2713.24 22.38 7 17 353 39.3 4.58 HVO_1348 probable YjeF family carbohydrate kinase 22.18 1 7 7 23 3.114E8 17.91 16.53 5 11 1251.99 22.18 7 12 478 48.8 4.45 HVO_1573 DNA gyrase subunit A 22.16 1 15 15 57 9.089E8 36.80 18.56 13 28 2811.29 22.16 15 29 862 94.8 4.56 HVO_0109 cysteine desulfurase 22.07 1 7 7 25 4.098E8 23.11 22.07 7 12 1920.84 22.07 7 13 426 46.8 4.56 HVO_1125 cysteine--tRNA ligase 22.06 1 7 7 22 2.387E8 16.66 22.06 7 11 1213.45 22.06 7 11 494 55.2 4.56 HVO_0876 methylglyoxal synthase 22.05 1 2 2 6 1.655E8 1.86 22.05 2 3 139.94 22.05 2 3 127 13.9 4.48 HVO_0812 phosphoenolpyruvate synthase 21.94 1 13 13 43 4.454E8 34.30 20.76 12 22 2349.59 20.76 12 21 761 83.1 4.63 HVO_1412 diphosphomevalonate decarboxylase 21.91 1 7 7 29 1.558E9 12.80 21.91 7 15 977.74 21.91 7 14 324 35.4 4.78 HVO_1816 dihydroorotase 21.91 1 5 5 19 1.672E8 10.62 21.91 5 9 738.83 21.91 5 10 429 45.4 4.40 HVO_0292 replication protein A 21.86 1 5 5 23 6.113E8 29.58 16.72 4 11 1494.88 21.86 5 12 311 34.6 4.31 HVO_2018 conserved hypothetical protein 21.85 1 2 2 3 3.221E8 0.00 21.85 2 3 119 13.4 4.73 HVO_1496 phosphotransferase system component I 21.77 1 11 11 43 5.586E8 28.52 21.77 11 21 2083.12 21.77 11 22 565 60.3 4.21 HVO_0511 NAD-dependent epimerase/dehydratase 21.76 1 4 4 15 2.162E8 5.42 21.76 4 7 595.81 21.76 4 8 262 29.3 4.78 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 21.55 1 6 6 22 6.219E8 18.05 21.55 6 12 1134.47 19.44 5 10 427 45.4 4.56 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 21.33 1 7 7 26 5.364E8 28.36 21.33 7 13 1462.94 21.33 7 13 347 36.8 4.93 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 21.27 1 5 5 18 4.989E8 15.03 21.27 5 9 956.16 21.27 5 9 362 39.6 4.82 HVO_0049 argininosuccinate synthase 21.23 1 7 7 23 1.175E9 13.79 21.23 7 13 1221.88 19.51 6 10 405 44.5 4.34 HVO_0601 homoserine dehydrogenase 21.20 1 5 5 28 2.600E8 26.27 21.20 5 14 1614.21 21.20 5 14 316 32.2 4.25 HVO_1437 conserved hypothetical protein 21.18 1 3 3 6 7.795E7 1.79 21.18 3 3 177.67 21.18 3 3 203 22.3 4.94 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 21.12 1 0 12 48 9.429E8 43.58 21.12 12 24 3241.33 21.12 12 24 644 66.0 8.12 HVO_2639 DUF1611 family protein 21.11 1 6 6 22 3.345E8 20.77 21.11 6 12 883.96 16.13 5 10 341 36.3 4.44 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 21.09 1 3 3 16 8.838E7 16.89 21.09 3 8 1188.94 21.09 3 8 128 13.0 4.31 HVO_0393 UvrABC system protein A 21.06 1 16 16 48 3.847E8 31.10 21.06 16 24 2034.26 21.06 16 24 983 108.6 4.82 HVO_0970 ribulose-bisphosphate carboxylase large subunit 21.01 1 7 7 33 6.295E8 25.20 21.01 7 16 1883.30 21.01 7 17 414 43.9 4.59 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 20.96 1 6 6 29 8.659E8 23.64 20.96 6 14 1550.40 20.96 6 15 415 44.4 4.41 HVO_1084 adenylosuccinate lyase 20.95 1 7 7 27 1.279E8 7.92 20.95 7 14 1260.12 20.95 7 13 463 50.8 4.70 HVO_2222 CYPL-type peptidylprolyl isomerase 20.93 1 2 2 3 1.140E8 283.38 20.93 2 3 172 18.7 4.44 HVO_1649 methionine adenosyltransferase 20.90 1 6 6 22 7.700E8 21.06 20.90 6 12 1222.99 20.90 6 10 402 43.5 4.45 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 20.80 1 6 6 24 2.176E8 10.77 17.13 5 12 1229.50 17.43 5 12 327 36.0 4.73 HVO_1896 30S ribosomal protein S24e 20.79 1 2 2 4 6.555E7 2.42 20.79 2 2 288.76 20.79 2 2 101 11.6 4.68 HVO_1885 TrkA domain protein 20.74 1 2 2 8 3.269E7 9.89 20.74 2 4 452.70 20.74 2 4 217 23.4 4.75 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 20.72 1 5 5 15 1.716E8 18.74 20.72 5 8 1118.39 16.22 4 7 333 36.7 4.56 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 8 1.363E7 9.99 20.71 2 4 716.04 20.71 2 4 140 16.0 5.57 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 20.56 1 21 21 66 7.393E8 45.34 15.89 17 30 3082.94 20.56 21 36 1284 141.2 4.35 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 20.38 1 4 4 18 1.573E8 21.26 20.38 4 9 1256.51 20.38 4 9 265 29.3 4.92 HVO_B0382 TATA-binding transcription initiation factor 20.21 1 3 3 13 1.559E8 6.96 20.21 3 7 471.64 20.21 3 6 188 20.1 4.12 HVO_0402 DUF124 family protein 20.00 1 3 3 10 5.144E8 4.28 16.44 2 4 352.70 20.00 3 6 225 24.0 4.58 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 19.94 1 11 11 44 9.522E8 28.14 18.36 10 21 2425.37 18.22 10 23 697 74.5 4.13 HVO_0789 tryptophan synthase alpha subunit 19.86 1 3 3 9 3.102E8 6.59 19.86 3 5 353.32 19.86 3 4 277 29.6 4.21 HVO_A0635 probable cysteine desulfurase 19.68 1 4 4 13 1.888E8 2.37 19.68 4 6 451.85 19.68 4 7 371 40.4 4.53 HVO_1407 HTH domain protein 19.56 1 3 3 9 1.717E8 2.10 19.56 3 4 373.02 19.56 3 5 225 24.9 4.45 HVO_0083 GlnK-type ammonia transport regulator 19.51 1 1 2 10 1.361E8 11.42 19.51 2 5 701.31 19.51 2 5 123 12.9 5.01 HVO_A0305 methylmalonate-semialdehyde dehydrogenase 19.43 1 7 7 27 1.185E9 24.43 19.43 7 14 1455.30 18.00 6 13 489 52.1 4.59 HVO_1572 DNA gyrase subunit B 19.25 1 11 11 32 2.657E8 16.82 17.68 10 16 1369.35 18.00 10 16 639 71.2 4.83 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 19.14 1 3 3 16 3.535E8 10.27 19.14 3 8 1038.07 19.14 3 8 324 33.6 3.99 HVO_1579 uridine phosphorylase 19.12 1 3 3 9 1.908E8 7.08 19.12 3 5 255.04 16.18 2 4 272 29.0 4.64 HVO_2266 hypothetical protein 19.07 1 6 6 29 2.870E8 2.59 19.07 6 15 931.31 19.07 6 14 493 56.7 4.54 HVO_0054 glycine--tRNA ligase 19.02 1 7 7 30 2.788E9 19.57 14.81 6 15 1410.67 16.50 6 15 594 64.9 4.21 HVO_0658 tRNA pseudouridine(13) synthase TruD 19.01 1 5 5 13 1.040E8 3.48 14.04 4 6 402.67 19.01 5 7 463 50.6 4.70 HVO_2417 conserved hypothetical protein 18.97 1 3 3 10 4.225E8 8.36 18.97 3 5 418.51 18.97 3 5 195 21.6 3.65 HVO_1289 OsmC domain protein 18.94 1 2 2 16 2.538E9 19.31 18.94 2 8 1407.35 18.94 2 8 132 14.2 3.85 HVO_A0458 ParA domain protein 18.90 1 3 3 14 2.423E8 13.16 18.90 3 7 656.83 18.90 3 7 291 32.2 4.79 HVO_0697 PAC2 family protein 18.82 1 2 2 6 4.081E8 8.80 18.82 2 3 413.00 18.82 2 3 255 27.4 4.08 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 18.82 1 7 7 23 2.360E8 12.37 18.82 7 12 869.73 18.82 7 11 473 50.8 4.58 HVO_0206 alanine--tRNA ligase 18.66 1 14 14 46 2.445E8 29.27 17.79 13 22 2256.41 18.66 14 24 922 102.4 4.54 HVO_1654 cysteine synthase 18.63 1 4 4 10 3.241E8 5.95 18.63 4 5 322.24 18.63 4 5 306 32.3 4.32 HVO_0916 diphthine synthase 18.59 1 3 3 8 2.286E8 3.65 18.59 3 4 316.42 18.59 3 4 269 29.1 4.54 HVO_2763 homolog to ribonuclease Z 18.55 1 4 4 14 4.634E8 6.94 18.55 4 8 552.60 18.55 4 6 248 26.6 4.53 HVO_A0302 asparaginase/glutaminase family protein 18.52 1 3 3 4 4.142E8 7.24 18.52 3 4 324 33.4 4.69 HVO_2848 probable PrkA-type serine/threonine protein kinase 18.49 1 10 10 33 3.035E8 28.64 18.49 10 17 1521.05 15.46 9 16 757 85.3 4.67 HVO_1657 phosphoribosylamine--glycine ligase 18.46 1 8 8 47 1.207E9 30.65 18.46 8 25 2375.16 17.06 7 22 428 45.5 4.20 HVO_2454 anthranilate synthase component I 18.32 1 7 7 16 2.153E8 8.39 18.32 7 9 612.26 13.55 5 7 524 55.9 4.56 HVO_1372 pyrroline-5-carboxylate reductase 18.29 1 4 4 11 2.761E8 11.19 18.29 4 6 689.81 18.29 4 5 257 26.8 4.01 HVO_2960 dihydrolipoamide S-acyltransferase 18.23 1 8 8 20 2.456E8 16.42 16.70 7 10 976.63 16.89 7 10 521 54.9 4.40 HVO_B0059 cobalt-precorrin 5A hydrolase 18.10 1 5 5 26 4.614E8 26.37 18.10 5 13 1586.84 18.10 5 13 326 34.5 4.51 HVO_0699 translation initiation factor aIF-2 alpha subunit 18.05 1 5 5 19 4.212E8 19.98 12.78 4 9 1159.96 18.05 5 10 266 29.5 4.46 HVO_1123 thioredoxin-disulfide reductase 18.05 1 6 6 25 5.507E8 5.69 14.04 4 11 1243.24 18.05 6 14 349 37.3 4.32 HVO_2948 phenylalanine--tRNA ligase alpha subunit 18.04 1 5 5 24 6.473E8 14.11 18.04 5 12 1151.98 18.04 5 12 499 55.1 4.41 HVO_2156 UspA domain protein 17.94 1 4 4 16 8.462E8 13.03 17.94 4 8 1077.20 17.94 4 8 301 31.6 4.69 HVO_0467 PhoU/TrkA-C domain protein 17.91 1 6 6 19 2.945E8 14.95 14.18 5 9 919.03 17.91 6 10 402 43.3 4.49 HVO_2333 conserved hypothetical protein 17.86 1 6 6 17 1.605E8 3.92 17.86 6 9 678.95 15.58 5 8 308 34.9 4.54 HVO_1804 nicotinate phosphoribosyltransferase 17.78 1 6 6 13 3.112E8 4.22 14.69 5 6 551.36 17.78 6 7 388 41.1 4.60 HVO_2614 uridine phosphorylase 17.77 1 3 3 21 1.554E9 24.37 17.77 3 11 1292.98 17.77 3 10 242 25.8 4.30 HVO_1683 4-alpha-glucanotransferase 17.74 1 7 7 15 1.758E8 5.49 17.74 7 8 429.72 15.93 6 7 496 56.3 4.45 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 17.73 1 6 6 17 2.097E8 8.44 17.73 6 10 636.39 13.48 4 7 423 43.9 4.31 HVO_0541 aconitate hydratase 17.70 1 10 10 39 8.692E8 18.02 17.70 10 20 1468.93 17.70 10 19 938 102.1 4.40 HVO_1568 alpha/beta hydrolase fold protein 17.69 1 4 4 19 2.452E8 14.01 17.69 4 10 1045.42 17.69 4 9 277 29.4 4.94 HVO_0354 30S ribosomal protein S7 17.65 1 3 3 13 6.788E8 7.86 17.65 3 7 772.05 17.65 3 6 204 22.6 5.14 HVO_2700 AAA-type ATPase (CDC48 subfamily) 17.64 1 10 11 33 3.784E8 19.70 17.64 11 18 1403.25 11.94 9 15 754 82.8 4.75 HVO_1284 GTP cyclohydrolase III 17.62 1 3 3 9 4.533E7 3.94 8.05 2 4 368.69 17.62 3 5 261 28.9 4.70 HVO_1853 UspA domain protein 17.57 1 2 2 4 4.517E7 2.12 17.57 2 2 185.41 17.57 2 2 148 16.0 4.58 HVO_A0296 probable oxidoreductase (short-chain dehydrogenase family) 17.53 1 3 3 4 1.816E8 0.00 17.53 3 4 251 26.1 4.72 HVO_2421 probable DNA-binding protein 17.45 1 4 4 8 1.167E8 4.44 17.45 4 4 353.20 13.62 3 4 235 25.8 4.89 HVO_0661 dCTP deaminase (dUMP-forming) 17.44 1 2 2 5 9.277E7 0.00 17.44 2 3 118.93 17.44 2 2 195 21.2 4.59 HVO_2008 archaeosine synthase 17.44 1 7 7 20 2.769E8 9.94 11.11 6 10 811.74 17.44 7 10 585 64.9 4.81 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 17.38 1 3 3 6 4.301E7 0.00 17.38 3 3 216.33 17.38 3 3 305 34.1 4.91 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 17.35 1 3 3 12 3.410E8 13.51 17.35 3 6 967.38 17.35 3 6 294 32.5 4.75 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 17.28 1 5 5 19 3.162E8 15.93 17.28 5 10 1179.15 17.28 5 9 324 36.6 4.68 HVO_1792 Lrp/AsnC family transcription regulator 17.28 1 2 2 4 1.880E8 6.72 17.28 2 2 382.16 17.28 2 2 162 18.1 4.34 HVO_1446 "fructose-1,6-bisphosphatase" 17.17 1 3 3 12 7.756E7 13.22 17.17 3 6 708.82 17.17 3 6 297 31.6 4.45 HVO_2793 conserved hypothetical protein 17.06 1 2 2 4 1.052E8 2.66 17.06 2 2 112.23 17.06 2 2 252 27.1 4.46 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 17.03 1 6 6 22 2.569E8 14.80 17.03 6 10 1026.91 17.03 6 12 634 66.1 4.54 HVO_2756 50S ribosomal protein L10 16.95 1 4 4 20 2.926E8 21.75 16.95 4 10 1319.91 16.95 4 10 348 36.9 3.99 HVO_2205 arNOG06768 family NADH-binding domain protein 16.94 1 4 4 21 8.586E7 17.86 16.94 4 10 1297.07 16.94 4 11 301 32.0 5.00 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 16.92 1 6 6 13 8.387E8 1.77 16.92 6 7 458.35 14.53 5 6 461 50.7 4.73 HVO_0349 DNA-directed RNA polymerase subunit A' 16.91 1 13 13 57 6.074E8 53.76 16.91 13 29 3904.16 16.91 12 28 976 108.8 4.81 HVO_2130 IclR family transcription regulator 16.91 1 5 5 15 1.145E8 4.65 16.91 4 7 689.37 16.54 4 8 272 30.1 5.55 HVO_0931 UspA domain protein 16.90 1 1 2 8 4.057E8 1.85 16.90 2 4 249.58 16.90 2 4 142 15.2 4.46 HVO_3014 origin-associated GTP-binding protein OapA 16.90 1 4 4 9 1.436E8 2.10 13.62 3 4 336.01 13.15 3 5 213 24.0 5.01 HVO_1268 conserved hypothetical protein 16.88 1 3 3 7 5.559E7 3.71 16.88 3 4 181.72 12.66 2 3 237 26.4 5.21 HVO_2189 phosphoribosylformylglycinamidine synthase component PurS 16.87 1 1 2 6 8.897E7 0.00 16.87 2 2 297.27 16.87 2 4 83 9.3 4.50 HVO_1553 hydroxypyruvate reductase 16.74 1 5 5 17 1.641E8 7.19 16.74 5 8 811.65 16.74 5 9 442 45.2 4.50 HVO_0358 homoserine dehydrogenase 16.72 1 4 4 18 9.319E8 11.37 16.72 4 9 880.36 16.72 4 9 317 32.4 4.44 HVO_0043 acetylornithine aminotransferase 16.67 1 4 4 15 2.753E8 11.39 16.67 4 8 1028.52 16.67 4 7 378 39.7 4.67 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 16.49 1 3 3 6 1.975E8 4.05 16.49 3 3 242.19 16.49 3 3 97 10.8 4.53 HVO_0745 "FtsZ family protein, type III" 16.39 1 3 3 6 1.166E8 0.00 16.39 3 3 205.15 16.39 3 3 360 37.1 4.51 HVO_0787 indole-3-glycerol-phosphate synthase 16.33 1 2 2 6 2.254E8 5.43 16.33 2 3 302.39 16.33 2 3 251 26.7 4.44 HVO_1323 "shikimate kinase, archaeal-type" 16.26 1 3 3 11 1.450E9 2.37 16.26 3 6 558.11 9.69 2 5 289 29.5 4.30 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 16.21 1 4 4 8 4.349E7 2.42 13.15 3 4 259.83 16.21 4 4 327 36.2 4.63 HVO_1048 phosphoribosylformylglycinamidine synthase 2 16.10 1 8 8 32 3.739E8 29.67 16.10 8 16 1935.09 14.81 7 16 702 72.9 4.18 HVO_B0277 HTH domain protein 16.03 1 2 2 6 5.736E7 0.00 16.03 2 3 127.38 16.03 2 3 262 29.5 4.50 7428712 "keratin 1, type II, cytoskeletal - human" 16.02 1 0 9 34 6.625E8 26.28 16.02 9 17 2208.83 16.02 9 17 643 65.5 6.35 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 16.02 1 3 3 13 1.272E8 8.79 16.02 3 6 856.74 16.02 3 7 231 25.0 4.25 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 16.00 1 3 3 7 1.958E9 0.00 11.43 2 3 225.90 16.00 3 4 175 18.8 4.63 HVO_0487 FMN-binding domain protein 15.89 1 2 2 2 6.118E7 0.00 15.89 2 2 151 17.3 4.70 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 15.79 1 4 4 5 6.643E7 1.99 12.38 3 3 100.15 8.67 2 2 323 34.9 5.24 HVO_2542 50S ribosomal protein L15 15.76 1 2 2 8 5.171E7 11.16 15.76 2 4 549.23 15.76 2 4 165 17.8 4.93 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 15.75 1 3 3 10 1.658E8 8.91 15.75 3 5 490.81 15.75 3 5 254 26.9 4.42 HVO_1413 probable NADH dehydrogenase 15.65 1 3 3 10 5.050E7 7.63 15.65 3 5 370.66 15.65 3 5 377 39.7 4.67 HVO_1547 isoleucine--tRNA ligase 15.63 1 10 10 66 8.906E8 69.95 15.63 10 33 4345.32 15.63 10 33 1043 117.9 4.30 HVO_1866 uridylate kinase 15.61 1 3 3 10 5.928E8 8.88 15.61 3 5 603.92 15.61 3 5 237 24.6 4.42 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 15.59 1 6 6 21 5.838E8 14.28 15.59 6 11 1134.25 10.08 5 10 526 57.2 4.31 HVO_0194 Orc1-type DNA replication protein 15.51 1 5 5 16 1.687E8 5.51 15.51 5 8 560.79 15.51 5 8 374 42.2 4.94 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 15.48 1 12 12 33 3.607E8 21.67 15.48 12 17 1620.01 13.59 10 16 898 97.7 4.45 HVO_0158 TATA-binding transcription initiation factor 15.34 1 2 3 18 1.474E9 3.93 15.34 3 9 876.20 15.34 3 9 189 20.3 4.22 HVO_0195 ribose-5-phosphate isomerase 15.22 1 3 3 11 4.552E8 6.43 11.74 2 5 697.67 15.22 3 6 230 23.2 4.54 HVO_1783 conserved hypothetical protein 15.18 1 2 2 6 3.731E7 3.81 15.18 2 3 288.84 15.18 2 3 224 24.1 5.90 HVO_1129 conserved hypothetical protein 15.13 1 3 4 8 1.697E8 4.49 13.85 3 4 333.23 11.28 3 4 390 43.0 4.44 HVO_1752 Lrp/AsnC family transcription regulator 15.08 1 2 2 6 1.393E8 3.83 15.08 2 3 258.44 15.08 2 3 199 21.7 4.60 HVO_2648 phosphoglycerate dehydrogenase 15.05 1 3 3 12 1.705E8 5.70 15.05 3 6 373.25 15.05 3 6 319 34.2 4.64 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 14.94 1 3 3 12 2.503E8 6.84 14.94 3 6 561.90 14.94 3 6 261 27.0 4.44 HVO_0826 peptidase M42 family protein 14.94 1 3 3 9 1.164E8 4.26 14.94 3 4 293.01 14.94 3 5 348 37.7 4.54 HVO_2168 AAA-type ATPase (MoxR subfamily) 14.89 1 4 4 12 5.174E7 6.72 14.89 4 6 356.52 14.89 4 6 329 35.9 4.54 HVO_0406 RNA-binding protein AU-1 14.74 1 4 4 9 2.228E9 1.87 14.74 4 5 162.30 9.62 3 4 468 49.9 4.53 HVO_2313 siroheme decarboxylase AhbB 14.73 1 2 2 6 6.349E8 8.65 14.73 2 3 483.56 14.73 2 3 353 39.6 4.64 HVO_1452 citryl-CoA lyase (citrate lyase beta subunit / ATP citrate synthase beta subunit) 14.70 1 2 2 4 2.114E7 0.00 14.70 2 2 80.88 14.70 2 2 279 29.0 4.54 HVO_2759 peptidase M42 family protein 14.69 1 5 5 16 5.344E8 9.73 14.69 5 8 744.69 14.69 5 8 354 37.0 4.40 HVO_1918 probable metallo-beta-lactamase family hydrolase 14.57 1 2 2 2 1.247E8 0.00 14.57 2 2 302 34.0 4.55 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 14.48 1 5 5 22 1.265E9 8.47 14.48 5 11 1092.22 14.48 5 11 373 40.2 4.44 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 14.48 1 5 5 19 1.362E8 15.67 14.48 5 10 1046.56 14.48 5 9 442 46.9 4.58 HVO_2761 mevalonate kinase 14.44 1 3 3 8 1.133E8 1.85 14.44 3 4 285.19 14.44 3 4 367 38.2 4.31 HVO_1823 UspA domain protein 14.38 1 2 2 8 6.707E8 9.93 14.38 2 4 554.56 14.38 2 4 153 16.4 4.60 HVO_2662 homolog to lactoylglutathione lyase 14.29 1 4 4 19 1.407E9 13.50 11.25 3 9 1097.57 14.29 4 10 329 36.5 4.48 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 14.23 1 2 3 9 1.257E8 6.45 14.23 3 5 349.29 14.23 3 4 267 28.8 4.55 HVO_1507 acetolactate synthase small subunit 14.22 1 3 3 10 1.420E8 8.12 14.22 3 5 807.97 14.22 3 5 218 23.7 4.94 HVO_2690 GFO family oxidoreductase 14.21 1 5 5 20 5.072E8 5.55 14.21 5 9 713.61 14.21 5 11 366 40.0 4.60 HVO_1578 probable NADH dehydrogenase 14.11 1 3 3 9 1.132E8 11.15 14.11 3 4 579.90 14.11 3 5 397 42.8 4.40 HVO_2239 UspA domain protein 14.08 1 2 2 2 1.066E8 3.85 14.08 2 2 142 15.4 4.16 HVO_1685 conserved hypothetical protein 14.02 1 6 6 15 3.942E8 4.52 11.99 5 7 699.62 14.02 6 8 492 54.5 5.74 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 13.98 1 3 3 10 2.098E8 5.43 13.98 3 6 327.58 13.98 3 4 422 43.6 4.72 HVO_2334 conserved hypothetical protein 13.96 1 3 3 5 3.591E7 0.00 6.55 2 2 117.54 13.96 3 3 351 38.6 4.37 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 13.92 1 2 2 3 1.780E7 0.00 13.92 2 3 388 41.9 4.35 HVO_2600 methionyl aminopeptidase 13.85 1 4 4 14 4.501E8 10.68 9.80 3 6 810.06 13.85 4 8 296 32.3 4.41 HVO_A0547 DUF1028 family protein 13.81 1 3 3 15 1.754E8 13.08 13.81 3 8 946.33 9.91 2 7 333 35.2 4.16 HVO_2951 tryptophan--tRNA ligase 13.80 1 4 4 7 1.320E8 0.00 10.21 3 3 179.92 13.80 4 4 529 59.1 4.53 HVO_0068 2-dehydropantoate 2-reductase 13.76 1 2 2 2 2.790E7 124.16 13.76 2 2 298 30.7 5.71 HVO_0431 HAD superfamily hydrolase 13.73 1 3 3 6 4.800E7 5.86 13.73 3 3 282.35 13.73 3 3 284 30.4 4.26 HVO_1809 isochorismatase family protein 13.68 1 2 2 2 1.795E8 114.70 13.68 2 2 190 21.0 4.55 HVO_B0371 aldehyde dehydrogenase 13.51 1 4 4 12 6.239E7 6.76 13.51 4 6 323.58 13.51 4 6 496 52.5 4.39 HVO_A0087 fumarylacetoacetase family protein 13.49 1 2 2 6 4.820E8 5.38 13.49 2 3 316.25 13.49 2 3 289 32.0 4.21 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 13.36 1 4 4 14 1.736E8 5.72 13.36 4 8 414.09 13.36 4 6 464 53.1 4.54 HVO_A0406 conserved hypothetical protein 13.33 1 1 4 11 3.417E8 6.59 13.33 4 6 498.48 7.65 3 5 405 44.4 5.30 HVO_0044 acetylglutamate kinase 13.15 1 3 3 8 1.276E8 8.06 13.15 3 4 538.77 13.15 3 4 327 33.2 4.49 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 13.01 1 6 6 23 5.333E8 16.93 11.54 5 11 1060.32 13.01 6 12 615 67.6 4.88 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 13.00 1 3 3 12 3.071E8 8.36 13.00 3 6 568.32 13.00 3 6 277 30.6 4.30 HVO_0558 SAMP-activating enzyme E1 12.96 1 2 2 3 1.251E8 172.22 12.96 2 3 270 28.7 4.35 HVO_B0055 conserved hypothetical protein 12.89 1 3 3 5 3.292E8 3.43 12.89 3 3 145.73 8.89 2 2 225 23.9 4.69 HVO_B0200 malate synthase 12.84 1 3 3 6 3.421E8 5.66 12.84 3 3 323.67 12.84 3 3 436 48.3 4.30 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 12.75 1 4 4 12 2.443E8 2.18 12.75 4 6 456.21 12.75 4 6 345 36.9 4.68 HVO_1295 histidinol-phosphate aminotransferase 12.74 1 3 3 8 4.882E7 6.83 12.74 3 4 448.58 8.31 2 4 361 39.4 4.51 HVO_C0069 GFO family oxidoreductase 12.65 1 3 3 6 4.397E7 1.71 12.65 3 4 119.62 5.86 2 2 324 36.0 5.10 HVO_B0060 precorrin-4 C11-methyltransferase 12.54 1 2 2 4 2.973E8 1.67 12.54 2 2 132.02 12.54 2 2 279 29.7 4.22 HVO_0997 peptidase M24 family protein 12.50 1 3 3 11 8.493E7 7.37 12.50 3 6 541.53 10.05 2 5 368 39.9 4.49 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 12.41 1 3 3 9 1.580E8 3.64 12.41 3 5 336.45 12.41 3 4 266 29.7 4.32 HVO_2547 50S ribosomal protein L32e 12.34 1 2 2 8 8.741E7 5.74 12.34 2 4 275.94 12.34 2 4 235 25.8 4.75 HVO_2297 deoxyhypusine synthase 12.26 1 2 2 3 1.903E8 2.10 12.26 2 3 359 38.6 4.59 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 12.21 1 3 3 5 4.297E7 2.76 8.72 2 2 250.61 12.21 3 3 344 37.0 4.55 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 12.20 1 6 6 16 1.827E8 4.20 10.59 5 7 645.07 8.19 5 9 623 62.1 5.30 HVO_1337 rpa-associated protein 12.20 1 6 6 23 8.476E8 11.21 12.20 6 13 898.73 10.43 5 10 623 64.8 3.68 HVO_0508 conserved hypothetical protein 12.16 1 2 2 6 1.899E7 4.03 12.16 2 3 251.35 12.16 2 3 148 16.0 3.92 HVO_0148 urease alpha subunit 12.15 1 4 4 9 1.343E8 5.59 12.15 4 5 289.24 10.04 3 4 568 60.3 4.54 HVO_1453 glutamate dehydrogenase (NADP) 11.99 1 4 4 12 3.423E8 9.16 11.99 4 6 535.39 11.99 4 6 417 45.7 4.49 HVO_2321 bacterial-type DNA primase DnaG 11.86 1 4 4 12 1.234E8 5.87 11.86 4 6 528.12 11.86 4 6 472 49.4 4.36 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 11.64 1 4 4 17 1.499E8 9.02 11.64 4 9 746.65 8.20 3 8 378 39.8 4.45 HVO_1949 conserved hypothetical protein 11.56 1 2 2 6 1.150E8 6.39 11.56 2 3 350.03 11.56 2 3 173 18.6 4.27 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 11.50 1 3 3 7 7.466E8 6.07 7.08 2 3 478.54 11.50 3 4 339 38.1 4.50 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 11.43 1 4 4 9 8.908E7 5.71 9.30 3 4 482.24 11.43 4 5 516 56.7 4.89 HVO_0123 signal recognition particle 54K protein 11.40 1 5 5 20 3.641E8 9.93 9.25 4 9 918.24 11.40 5 11 465 50.9 4.50 HVO_2072 S-layer glycoprotein 11.37 1 4 4 42 3.203E9 18.05 11.37 4 19 1630.90 11.37 4 23 827 85.1 3.65 HVO_0853 DNA double-strand break repair protein Mre11 11.34 1 3 3 7 2.623E8 6.91 11.34 3 4 242.66 7.94 2 3 441 48.1 4.39 HVO_1387 enoyl-CoA hydratase 11.28 1 3 3 16 6.141E7 4.98 11.28 3 8 752.60 11.28 3 8 257 27.5 4.51 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 11.16 1 4 4 12 1.069E8 6.30 11.16 4 6 439.08 11.16 4 6 430 45.1 4.50 HVO_1625 conserved hypothetical protein 11.16 1 5 5 13 1.969E8 16.57 11.16 5 7 775.13 9.79 4 6 654 70.1 4.04 HVO_2702 alpha/beta hydrolase fold protein 11.15 1 2 2 5 9.748E7 1.63 11.15 2 3 169.41 11.15 2 2 260 28.0 4.53 HVO_0041 ornithine carbamoyltransferase 11.04 1 3 3 7 2.492E8 4.78 11.04 3 3 269.32 11.04 3 4 299 32.7 4.37 HVO_1354 DNA mismatch repair protein MutS 11.03 1 5 5 14 1.441E8 2.09 9.48 4 7 469.76 7.24 4 7 580 62.1 4.56 HVO_0469 AstE family protein 11.01 1 3 3 10 1.731E8 5.20 11.01 3 5 566.33 11.01 3 5 318 33.9 5.85 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 11.01 1 3 3 7 2.546E8 0.00 8.15 2 3 242.90 11.01 3 4 454 48.5 4.46 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 10.96 1 3 3 11 1.079E8 1.76 7.12 2 5 399.98 10.96 3 6 365 39.0 4.61 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 10.86 1 1 2 8 2.602E8 4.45 10.86 2 4 361.82 10.86 2 4 267 29.1 4.63 HVO_2536 CHP00300 family protein 10.82 1 2 2 5 2.449E8 2.16 10.82 2 2 150.64 10.82 2 3 416 44.8 4.51 HVO_C0044 PLD domain protein 10.81 1 2 2 2 8.403E7 116.52 10.81 2 2 333 36.4 4.94 HVO_2846 SpoVR family protein 10.76 1 6 6 17 2.001E8 5.87 10.76 6 8 459.76 10.76 6 9 669 78.0 4.82 HVO_1098 diaminopimelate decarboxylase 10.60 1 4 4 15 3.667E8 8.81 10.60 4 8 571.59 10.60 4 7 415 44.4 5.02 HVO_2160 conserved hypothetical protein 10.59 1 16 16 136 3.292E9 155.92 10.23 15 69 11149.20 10.59 16 67 2257 232.7 3.92 HVO_1491 HAD superfamily hydrolase 10.54 1 3 3 14 8.256E7 5.72 10.54 3 7 706.31 10.54 3 7 408 44.4 4.60 HVO_B0026 probable oxidoreductase (short-chain dehydrogenase family) 10.51 1 2 2 3 3.069E7 213.36 10.51 2 3 257 26.7 4.55 HVO_1710 alpha amylase 10.49 1 6 6 18 3.184E8 4.32 10.49 6 9 790.57 10.49 6 9 677 75.0 4.45 HVO_A0586 sugar nucleotidyltransferase 10.46 1 3 3 12 2.763E8 4.45 10.46 3 6 572.93 10.46 3 6 411 43.7 4.69 HVO_2952 tRNA-splicing endonuclease 10.32 1 2 2 9 1.631E8 1.79 10.32 2 4 298.63 10.32 2 5 339 37.4 4.74 HVO_2001 tRNA-guanine(15) transglycosylase 10.27 1 3 3 8 3.955E7 5.55 10.27 3 5 225.13 6.78 2 3 516 56.3 4.59 HVO_2507 Lrp/AsnC family transcription regulator 10.22 1 2 2 6 7.944E7 1.66 10.22 2 3 209.34 10.22 2 3 137 15.5 4.67 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 10.19 1 2 2 6 6.098E7 5.87 10.19 2 3 303.94 10.19 2 3 265 28.7 4.87 HVO_1867 lysine--tRNA ligase 10.09 1 5 5 10 2.977E8 0.00 10.09 5 6 351.49 6.85 3 4 555 62.1 4.46 HVO_0304 electron transfer flavoprotein alpha subunit 10.09 1 2 2 3 2.190E8 252.98 10.09 2 3 317 33.5 4.18 HVO_2071 conserved hypothetical protein 10.02 1 5 5 20 5.849E8 18.11 10.02 5 10 1019.84 10.02 5 10 549 58.4 4.72 HVO_0464 threonine ammonia-lyase 9.93 1 3 3 8 8.431E7 2.08 9.93 3 3 309.48 9.93 3 5 403 43.7 4.72 31559823 keratin 25D [Homo sapiens] 9.91 1 1 2 3 6.140E7 137.28 9.91 2 3 464 50.6 5.47 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 9.89 1 3 3 14 1.236E8 10.55 9.89 3 7 700.91 9.89 3 7 475 49.3 4.49 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 9.85 1 3 3 6 5.714E7 6.26 9.85 3 3 236.71 9.85 3 3 406 43.1 4.60 HVO_2481 HD family hydrolase 9.74 1 2 2 4 1.528E8 10.98 9.74 2 4 390 42.7 6.14 HVO_1373 acyl-CoA dehydrogenase 9.66 1 2 2 6 7.791E7 4.37 9.66 2 3 272.16 9.66 2 3 383 42.5 4.61 HVO_0867 HD family hydrolase 9.57 1 2 2 6 1.107E8 2.61 9.57 2 3 258.40 9.57 2 3 230 26.2 4.78 HVO_2847 conserved hypothetical protein 9.57 1 4 4 12 1.846E8 6.22 9.57 4 6 561.74 9.57 4 6 439 50.1 4.53 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 9.52 1 2 2 8 9.498E7 3.75 9.52 2 5 284.32 9.52 2 3 189 21.7 4.46 HVO_A0039 hypothetical protein 9.51 1 2 2 2 1.196E7 2.12 9.51 2 2 326 35.6 4.60 HVO_0639 AAA-type ATPase (MoxR subfamily) 9.49 1 3 3 14 1.306E8 6.62 9.49 3 7 681.96 9.49 3 7 316 34.7 4.89 HVO_2501 alpha/beta hydrolase fold protein 9.49 1 2 2 6 5.398E7 9.55 9.49 2 3 417.42 9.49 2 3 316 35.3 5.72 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 9.43 1 7 7 23 1.319E8 23.46 8.69 6 12 1254.45 7.58 6 11 1082 117.2 4.32 HVO_2757 50S ribosomal protein L1 9.43 1 2 2 6 3.850E8 5.85 9.43 2 3 287.33 9.43 2 3 212 23.1 4.42 HVO_1629 conserved hypothetical protein 9.42 1 3 3 3 1.197E8 130.84 9.42 3 3 531 56.3 4.69 HVO_1501 DeoR family transcription regulator GlpR 9.41 1 2 2 8 2.536E7 8.39 9.41 2 4 479.09 9.41 2 4 255 28.0 4.97 HVO_1073 ThiJ/PfpI family protein 9.38 1 2 2 6 1.889E7 4.76 9.38 2 3 284.54 9.38 2 3 224 23.9 4.12 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 9.35 1 3 3 8 1.379E8 2.37 9.35 3 4 348.61 5.95 2 4 353 36.7 4.65 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 9.30 1 4 4 28 4.245E8 18.74 9.30 4 14 1462.63 9.30 4 14 430 44.2 4.37 HVO_0452 leucine--tRNA ligase 9.29 1 7 7 30 3.627E8 17.35 9.29 7 16 1318.05 9.29 7 14 958 109.5 4.37 HVO_0818 threonine synthase 9.25 1 3 3 18 5.522E8 9.87 9.25 3 9 834.71 9.25 3 9 389 40.8 4.31 HVO_A0133 conserved hypothetical protein 9.25 1 2 2 2 0.000E0 96.07 9.25 2 2 292 30.8 5.17 HVO_2350 YyaL family protein 9.24 1 3 3 10 1.720E8 2.98 9.24 3 5 334.38 9.24 3 5 552 58.8 4.59 47132620 keratin 2a [Homo sapiens] 9.23 1 2 4 13 3.574E8 10.79 9.23 4 7 858.68 5.01 3 6 639 65.4 8.00 HVO_2945 valine--tRNA ligase 9.08 1 6 6 28 2.294E8 16.83 7.59 5 13 1623.30 9.08 6 15 870 98.9 4.36 HVO_0979 NADH dehydrogenase-like complex subunit B 9.01 1 2 2 6 1.817E8 6.77 9.01 2 3 341.36 9.01 2 3 233 26.1 5.01 HVO_0681 DNA topoisomerase I 8.81 1 6 6 14 8.585E7 7.19 6.07 4 6 841.92 8.81 6 8 840 93.6 4.58 HVO_0321 peptide chain release factor aRF-1 8.70 1 3 3 5 1.107E8 4.03 8.70 3 3 239.39 5.56 2 2 414 46.6 4.83 HVO_0305 electron transfer flavoprotein beta subunit 8.68 1 2 2 6 2.892E8 2.03 8.68 2 3 261.31 8.68 2 3 265 28.5 4.04 HVO_1847 oligoendopeptidase PepF 8.68 1 4 4 10 7.971E7 10.03 8.68 4 5 544.30 8.68 4 5 599 68.5 4.41 HVO_2665 HpcH/HpaI aldolase family protein 8.68 1 2 2 6 6.791E7 5.82 8.68 2 3 255.10 8.68 2 3 265 28.3 4.50 HVO_1020 HEAT-PBS family protein 8.59 1 3 3 11 1.521E8 6.80 8.59 3 6 433.69 6.44 2 5 419 45.5 3.95 HVO_1957 proteasome-activating nucleotidase 8.50 1 3 3 8 6.847E7 2.06 8.50 3 4 334.53 5.34 2 4 412 45.6 4.48 HVO_B0115 fumarylacetoacetase family protein 8.48 1 2 2 8 4.795E8 10.13 8.48 2 4 504.11 8.48 2 4 283 30.3 4.21 HVO_2503 kynureninase 8.47 1 3 3 13 2.084E8 5.21 8.47 3 6 795.50 8.47 3 7 425 46.0 4.54 HVO_A0254 DUF234 domain protein 8.46 1 3 3 4 2.535E7 0.00 6.94 2 2 125.25 4.12 2 2 461 52.7 4.78 HVO_1008 GFO family oxidoreductase 8.43 1 3 3 5 8.344E7 0.00 8.43 3 3 208.54 5.72 2 2 332 36.0 4.72 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 8.43 1 2 2 4 1.837E7 3.08 8.43 2 2 273.23 8.43 2 2 344 39.1 4.73 HVO_2880 probable peptide chain release factor pelota 8.43 1 2 2 6 2.189E8 4.08 8.43 2 3 228.20 8.43 2 3 356 39.3 4.63 HVO_1531 UDP-glucose 6-dehydrogenase 8.37 1 3 3 18 1.714E8 6.91 8.37 3 9 720.51 8.37 3 9 430 45.9 4.50 HVO_2053 "probable glycosyltransferase, type 1" 8.20 1 2 2 4 5.149E7 1.98 8.20 2 2 129.34 8.20 2 2 378 41.9 4.67 HVO_1309 peptidase M24 family protein 8.18 1 3 3 9 8.308E7 7.77 8.18 3 5 417.94 8.18 3 4 391 42.1 4.36 HVO_0968 NADH dehydrogenase-like complex subunit CD 8.16 1 0 4 11 2.302E8 8.51 8.16 4 5 634.91 8.16 4 6 564 63.3 4.60 HVO_0322 MinD/ParA domain protein 8.09 1 2 2 4 0.000E0 3.20 8.09 2 2 211.96 8.09 2 2 581 58.8 3.70 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 8.01 1 2 2 6 2.599E7 0.00 8.01 2 4 108.22 8.01 2 2 574 62.8 4.17 HVO_1371 glutamate 5-kinase 7.97 1 2 2 4 2.963E8 4.06 7.97 2 2 168.37 7.97 2 2 301 32.0 4.25 HVO_1914 acetyl-CoA C-acyltransferase 7.96 1 2 2 6 5.235E7 6.23 7.96 2 3 325.80 7.96 2 3 377 39.9 4.41 HVO_0854 DNA double-strand break repair ATPase Rad50 7.95 1 5 5 10 7.147E7 4.09 7.95 5 5 297.53 6.72 4 5 893 100.0 4.58 HVO_0868 NAD-dependent epimerase/dehydratase 7.90 1 3 3 8 9.672E7 1.77 7.90 3 4 200.06 7.90 3 4 329 36.1 4.55 HVO_1327 AAA-type ATPase (CDC48 subfamily) 7.74 1 3 4 8 1.756E8 6.59 3.67 2 3 419.35 7.74 4 5 736 78.1 4.88 HVO_A0432 conserved hypothetical protein 7.65 1 0 3 10 8.279E7 6.59 7.65 3 5 498.48 7.65 3 5 405 44.5 5.24 HVO_1356 sensor box histidine kinase 7.64 1 2 2 8 1.630E8 2.26 7.64 2 4 306.73 7.64 2 4 550 61.1 4.60 HVO_2812 AstE family protein 7.62 1 2 2 6 4.015E7 0.00 7.62 2 3 110.50 7.62 2 3 341 37.3 5.14 HVO_1374 acyl-CoA synthetase 7.59 1 3 3 9 9.025E7 8.27 7.59 3 5 573.07 5.42 2 4 553 61.1 4.50 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 7.59 1 3 3 11 3.099E8 11.76 7.59 3 5 626.07 7.59 3 6 474 53.4 4.59 HVO_2158 malic enzyme (NADP) 7.59 1 0 4 21 3.755E8 18.63 7.59 4 11 1180.07 6.26 3 10 751 81.4 4.55 HVO_1340 "probable glycosyltransferase, type 1" 7.47 1 3 3 12 1.652E8 1.83 7.47 3 6 546.33 7.47 3 6 375 41.0 4.42 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 7.42 1 2 2 3 1.841E7 4.35 7.42 2 3 512 53.8 4.78 HVO_1895 KEOPS complex subunit Kae1/Bud32 7.25 1 2 2 4 7.294E7 6.30 7.25 2 2 222.88 7.25 2 2 552 59.0 5.07 HVO_B0319 IclR family transcription regulator 7.20 1 2 2 2 4.610E7 121.70 7.20 2 2 264 29.3 5.14 HVO_3000 DNA ligase (NAD) 7.15 1 4 4 13 3.362E8 14.08 7.15 4 7 642.68 7.15 4 6 699 75.8 4.50 HVO_2256 DUF262 family protein 7.14 1 3 3 10 4.438E7 4.88 7.14 3 5 392.17 7.14 3 5 462 54.9 4.89 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 7.12 1 2 2 4 1.238E8 2.42 7.12 2 2 118.96 7.12 2 2 337 35.9 4.69 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 7.09 1 2 2 4 1.567E8 368.44 7.09 2 4 395 42.4 4.54 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 8 1.252E8 6.91 7.07 2 4 416.36 7.07 2 4 297 32.3 3.98 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 6.95 1 2 2 6 1.057E8 4.46 6.95 2 3 302.74 6.95 2 3 403 41.1 4.73 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 6.69 1 2 2 12 4.566E8 11.55 6.69 2 6 610.12 6.69 2 6 299 32.0 4.53 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 6.67 1 2 2 19 3.395E8 15.49 6.67 2 10 1131.89 6.67 2 9 360 39.5 4.31 HVO_A0180 SMC-like protein Sph1 6.58 1 2 3 3 0.000E0 131.92 6.58 3 3 593 66.4 4.58 HVO_B0183 YgeA family protein 6.53 1 2 2 2 1.212E8 2.08 6.53 2 2 245 26.8 4.58 HVO_1079 sulfate adenylyltransferase small subunit 6.46 1 2 2 4 2.467E8 0.00 6.46 2 2 162.76 6.46 2 2 325 37.5 4.18 HVO_0670 glutathione S-transferase 6.44 1 2 2 2 1.096E8 131.40 6.44 2 2 326 38.1 4.56 HVO_1375 O-succinylbenzoic acid--CoA ligase 6.35 1 3 3 5 8.941E7 4.57 6.35 3 3 278.36 4.56 2 2 614 64.7 4.28 HVO_C0042 helicase domain protein 6.20 1 6 6 18 2.021E8 16.31 6.20 6 10 923.29 5.34 5 8 1274 144.4 4.67 HVO_0048 argininosuccinate lyase 6.15 1 2 2 6 7.495E7 0.00 6.15 2 3 212.02 6.15 2 3 488 50.8 4.53 HVO_0096 arNOG08307 family NADH-binding domain protein 6.13 1 2 2 8 8.254E7 7.85 6.13 2 4 436.91 6.13 2 4 310 33.3 5.05 HVO_0733 transcription initiation factor TFB 6.13 1 0 2 8 2.915E8 5.37 6.13 2 4 492.00 6.13 2 4 326 37.2 6.00 HVO_1058 TrkA domain protein 6.07 1 2 2 5 8.443E7 0.00 6.07 2 2 153.90 6.07 2 3 445 47.7 4.35 HVO_B0143 receiver/sensor box histidine kinase 6.03 1 3 3 7 1.704E8 4.71 6.03 3 4 303.81 6.03 3 3 597 66.0 4.41 HVO_2058 NAD-dependent epimerase/dehydratase (homolog to dTDP-4-dehydrorhamnose reductase) 6.00 1 2 2 3 4.877E8 2.38 6.00 2 3 300 32.0 4.22 HVO_1510 2-isopropylmalate synthase 5.91 1 2 2 6 5.123E8 2.38 5.91 2 3 221.25 5.91 2 3 440 47.7 4.82 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 5.88 1 2 2 6 8.966E7 0.00 5.88 2 3 238.10 5.88 2 3 459 50.5 4.63 HVO_0893 methylmalonyl-CoA mutase subunit A 5.83 1 2 2 8 4.909E7 6.30 5.83 2 4 361.04 5.83 2 4 566 63.1 4.36 HVO_C0057 Orc1-type DNA replication protein 5.74 1 2 2 4 2.433E7 0.00 5.74 2 2 66.54 5.74 2 2 418 46.3 5.02 HVO_1908 assimilatory nitrate reductase 5.71 1 2 2 4 0.000E0 0.00 5.71 2 2 35.43 5.71 2 2 700 74.2 4.61 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 5.63 1 2 2 3 2.640E7 1.64 5.63 2 3 444 47.1 4.77 40354192 keratin 10 [Homo sapiens] 5.31 1 0 4 11 5.788E7 4.44 5.31 4 5 425.97 5.31 4 6 584 58.8 5.16 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 5.23 1 0 4 11 5.788E7 4.44 5.23 4 5 425.97 5.23 4 6 593 59.5 5.21 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 5.23 1 3 3 11 2.425E8 9.41 5.23 3 6 782.90 3.92 2 5 612 67.3 4.16 HVO_1979 tRNA pseudouridine synthase Pus10 5.15 1 2 2 6 7.269E8 5.11 5.15 2 3 410.19 5.15 2 3 427 46.9 4.39 HVO_1113 "FtsZ family protein, type III" 5.14 1 0 2 7 4.276E8 0.00 5.14 2 3 228.09 5.14 2 4 389 40.8 4.89 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 5.08 1 2 2 4 1.329E8 0.00 5.08 2 2 110.31 5.08 2 2 492 52.1 4.83 HVO_A0498 conserved hypothetical protein 5.01 1 2 2 2 7.504E7 2.28 5.01 2 2 379 42.7 4.55 HVO_0552 DNA mismatch repair protein MutS 4.98 1 4 4 13 1.151E8 6.18 4.98 4 7 461.03 3.79 3 6 924 99.2 4.65 HVO_2024 conserved hypothetical protein 4.90 1 2 2 6 6.208E7 0.00 4.90 2 3 164.06 4.90 2 3 408 41.8 4.26 HVO_2883 conserved hypothetical protein 4.84 1 3 3 4 8.159E7 4.05 4.84 3 4 702 78.9 4.48 HVO_1711 glucoamylase 4.77 1 6 6 15 9.988E7 6.85 4.77 6 8 531.34 4.77 6 7 1511 166.1 4.64 HVO_B0154 receiver/sensor box histidine kinase 4.69 1 4 4 13 3.559E7 10.76 2.92 3 6 451.28 4.69 4 7 1301 144.1 4.39 HVO_A0299 ABC-type transport system periplasmic substrate-binding protein (probable substrate spermidine/putrescine) 4.69 1 2 2 4 1.032E8 0.00 4.69 2 2 88.71 4.69 2 2 469 51.0 4.11 HVO_C0043 conserved hypothetical protein 4.69 1 3 3 5 6.088E7 2.09 4.69 3 3 154.85 3.33 2 2 661 73.8 4.75 HVO_A0158 acyl-CoA synthetase 4.62 1 0 3 19 8.212E8 12.00 4.62 3 10 1016.21 4.62 3 9 650 71.2 4.63 HVO_B0038A D-xylonate dehydratase 4.61 1 0 2 12 3.369E8 10.08 4.61 2 6 701.93 4.61 2 6 412 45.5 4.55 HVO_B0233 alpha-L-arabinofuranosidase 4.50 1 2 2 2 6.743E7 1.63 4.50 2 2 511 57.5 4.39 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 4.44 1 2 2 2 1.579E8 1.64 4.44 2 2 586 63.4 4.70 HVO_2356 GNAT family acetyltransferase 4.42 1 2 2 2 1.144E7 0.00 4.42 2 2 407 45.1 4.64 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 4.30 1 2 2 4 1.284E8 0.00 4.30 2 2 100.94 4.30 2 2 838 89.1 4.65 HVO_0311 A-type ATP synthase subunit I 3.96 1 2 2 2 1.384E8 217.79 3.96 2 2 733 79.5 4.41 HVO_0415 repair helicase 3.90 1 2 2 3 7.271E7 166.54 3.90 2 3 616 69.6 4.70 HVO_2427 replication factor C large subunit 3.89 1 2 2 5 7.432E7 3.66 3.89 2 3 151.46 3.89 2 2 488 53.4 4.67 HVO_2721 amidophosphoribosyltransferase 3.85 1 2 2 2 7.638E7 1.80 3.85 2 2 493 53.4 4.78 HVO_C0001 Orc1-type DNA replication protein 3.68 1 2 2 3 3.820E7 1.69 3.68 2 3 408 45.2 4.97 HVO_A0550 receiver/sensor box histidine kinase 3.05 1 3 3 7 4.863E7 1.64 3.05 3 4 210.06 1.81 2 3 885 95.9 4.46 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 2.97 1 2 2 4 1.200E8 1.61 2.97 2 4 706 73.3 4.39 HVO_0551 DNA mismatch repair protein MutL 2.72 1 2 2 3 3.031E7 4.69 2.72 2 3 735 78.7 4.50 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 2.70 1 2 2 2 3.296E7 2.33 2.70 2 2 740 85.6 4.70 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 1.87 1 2 2 2 1.284E7 0.00 1.87 2 2 1335 150.5 4.60 HVO_0689 chromosome segregation protein Smc 1.61 1 2 2 5 4.553E7 3.45 1.61 2 2 219.99 1.61 2 3 1240 138.1 4.39