Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_2757 50S ribosomal protein L1 88.21 1 15 15 459 1.518E9 640.76 83.49 14 226 29437.26 88.21 15 233 212 23.1 4.42 HVO_2548 50S ribosomal protein L6 78.09 1 10 10 224 3.975E8 261.12 76.97 8 104 15173.69 78.09 10 120 178 19.6 4.68 HVO_1454 aspartate carbamoyltransferase catalytic subunit 77.63 1 14 14 82 4.659E7 83.49 77.63 14 41 4288.21 77.63 14 41 304 33.7 4.92 HVO_2564 50S ribosomal protein L3 77.51 1 21 21 586 1.540E9 486.07 75.15 19 294 30660.07 77.51 21 292 338 37.2 6.68 HVO_2545 50S ribosomal protein L18 77.17 1 6 6 66 2.564E8 77.38 77.17 6 32 3655.89 77.17 6 34 184 20.2 5.60 HVO_0455 thermosome subunit 2 75.22 1 40 41 1885 1.907E9 2624.93 74.15 39 939 133183.80 75.22 41 946 557 59.3 4.37 HVO_0356 translation elongation factor aEF-2 74.69 1 42 42 727 1.093E9 782.57 74.69 42 357 37494.25 74.69 42 370 727 80.4 4.73 HVO_0133 thermosome subunit 1 74.64 1 32 33 1360 2.422E9 1603.54 74.64 33 661 74607.25 74.64 33 699 560 58.9 4.25 HVO_A0207 CRISPR-associated protein Cas7 74.41 1 15 15 188 3.045E8 209.10 74.41 15 93 10124.45 74.41 15 95 340 38.2 4.54 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 73.52 1 15 15 90 1.377E8 99.70 73.52 15 45 4690.09 73.52 15 45 355 38.2 4.68 HVO_2380 AAA-type ATPase (CDC48 subfamily) 73.49 1 53 53 531 6.812E8 528.20 73.49 52 263 28148.74 73.49 53 268 743 81.9 4.82 HVO_0778 thermosome subunit 3 72.33 1 33 34 1320 2.472E9 1833.05 71.37 33 664 88459.99 72.33 34 656 524 55.2 4.59 HVO_0239 glutamine synthetase 71.49 1 31 31 2044 5.726E9 2622.40 64.04 29 1017 132876.56 70.39 30 1027 456 50.5 4.56 HVO_0329 branched-chain amino acid aminotransferase 71.15 1 19 19 236 4.100E8 297.71 71.15 19 114 16092.62 71.15 19 122 312 35.0 4.58 HVO_1858 30S ribosomal protein S19e 70.20 1 7 7 46 5.546E7 43.49 58.28 6 20 2998.38 70.20 7 26 151 16.7 4.84 HVO_2900 fumarate hydratase 70.15 1 23 23 190 5.378E8 226.03 70.15 23 97 10447.53 68.87 21 93 469 50.1 4.78 HVO_2779 50S ribosomal protein L18e 69.83 1 9 9 87 2.891E8 131.99 69.83 9 45 5745.92 69.83 9 42 116 12.7 8.50 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 68.86 1 16 16 210 3.437E8 229.46 68.86 16 105 11134.83 68.86 16 105 350 37.6 4.54 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 68.24 1 19 19 157 2.704E8 185.44 60.00 18 78 10337.10 68.24 18 79 340 38.8 4.58 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 67.61 1 33 33 234 2.615E8 265.83 67.61 33 117 13715.76 61.77 31 117 599 65.3 4.51 HVO_1400 ABC-type transport system ATP-binding protein (probable substrate sugar) 66.47 1 21 21 109 7.921E7 110.77 66.47 21 56 5516.71 66.47 21 53 519 56.8 4.68 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 65.85 1 13 13 274 8.382E8 245.28 65.85 13 136 14398.93 65.85 13 138 287 31.0 4.73 HVO_0359 translation elongation factor aEF-1 alpha subunit 65.32 1 15 18 555 1.369E9 609.19 59.62 16 255 35582.99 65.32 18 300 421 45.7 4.73 HVO_2636 PspA domain protein 65.22 1 15 15 150 2.763E8 196.78 65.22 15 76 9863.06 61.23 13 74 276 30.9 4.61 HVO_0313 A-type ATP synthase subunit E 64.95 1 9 10 54 1.040E8 46.22 46.91 7 20 3691.83 64.95 10 34 194 22.0 4.31 HVO_2756 50S ribosomal protein L10 64.66 1 13 13 294 5.045E8 383.59 64.66 13 144 16520.84 64.66 13 150 348 36.9 3.99 HVO_2724 beta-lactamase domain protein 64.44 1 24 24 371 1.123E9 366.08 64.44 24 182 19503.50 64.44 24 189 450 50.1 5.40 HVO_1273 inosine-5'-monophosphate dehydrogenase 63.45 1 19 19 311 3.324E8 329.38 60.84 18 152 15235.77 63.45 19 159 498 53.3 4.55 HVO_2862 serine hydroxymethyltransferase 63.37 1 14 14 140 2.087E8 169.03 63.37 14 71 8269.87 63.37 14 69 415 44.3 4.53 HVO_2563 50S ribosomal protein L4 63.31 1 10 10 102 2.896E8 111.57 63.31 10 51 6073.18 63.31 10 51 248 27.0 6.44 HVO_2759 peptidase M42 family protein 62.99 1 17 17 145 1.655E8 188.64 62.99 17 72 8925.72 62.99 17 73 354 37.0 4.40 HVO_B0132 PQQ repeat protein 62.72 1 14 14 122 1.221E8 123.70 62.72 14 61 6639.80 62.72 14 61 405 41.9 4.64 HVO_0536 ferritin 62.50 1 6 6 53 6.919E7 58.39 62.50 6 26 2737.90 62.50 6 27 176 19.9 4.50 HVO_0980 NADH dehydrogenase-like complex subunit CD 62.30 1 21 28 380 8.519E8 388.38 52.42 26 186 23275.60 61.22 27 194 557 63.4 4.53 HVO_1145 30S ribosomal protein S1e 62.27 1 16 16 354 8.990E8 395.89 61.82 15 179 18084.21 62.27 16 175 220 24.8 4.86 HVO_2524 phytoene synthase 61.95 1 16 16 92 1.678E8 93.99 61.95 16 46 5886.21 52.51 15 46 339 38.3 4.82 HVO_2205 arNOG06768 family NADH-binding domain protein 61.79 1 13 13 102 8.504E7 145.88 61.79 13 51 6433.44 61.79 13 51 301 32.0 5.00 HVO_0677 aspartate--tRNA ligase 61.52 1 19 19 237 5.376E8 265.14 61.52 19 118 13906.76 61.52 19 119 434 48.7 4.50 HVO_2560 30S ribosomal protein S19 60.71 1 7 7 58 7.954E7 48.87 60.71 7 30 2818.29 60.71 7 28 140 16.0 5.57 HVO_0581 "cell division protein FtsZ, type II" 60.50 1 17 17 141 2.388E8 198.68 58.50 16 72 8028.63 60.50 17 69 400 42.5 4.75 HVO_2336 pyridoxal biosynthesis lyase PdxS 60.26 1 13 13 117 2.796E8 115.31 56.29 10 52 7569.06 60.26 13 65 302 32.5 4.81 HVO_0817 phytoene dehydrogenase (phytoene desaturase) 60.24 1 23 23 167 2.190E8 182.18 60.24 23 83 9607.74 59.06 22 84 425 46.1 4.98 HVO_1257 AAA-type ATPase (MoxR subfamily) 60.06 1 16 16 70 6.092E7 83.94 57.40 15 34 3971.33 60.06 16 36 338 37.4 4.67 HVO_0317 A-type ATP synthase subunit B 59.83 1 21 21 398 1.894E9 471.26 59.83 21 199 22698.31 59.83 21 199 468 51.9 4.25 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 59.48 1 15 15 131 1.463E8 151.14 59.48 15 65 7402.15 59.48 15 66 422 43.6 4.72 HVO_1921 serine--tRNA ligase 59.35 1 21 21 134 6.997E7 137.82 59.35 21 67 7817.39 51.30 20 67 460 52.0 4.46 HVO_1346 GTP-binding protein HflX 58.89 1 23 23 107 9.452E7 127.06 58.89 23 54 5912.03 58.89 23 53 433 48.2 4.73 HVO_0725 probable oxidoreductase (short-chain dehydrogenase family) 58.72 1 14 14 159 3.834E8 190.69 58.72 14 79 10060.85 58.72 14 80 281 30.2 4.78 HVO_3014 origin-associated GTP-binding protein OapA 58.69 1 12 12 56 8.800E7 53.65 55.40 11 28 2434.60 58.69 12 28 213 24.0 5.01 HVO_0801 stomatin family protein 58.49 1 22 28 524 2.121E9 627.14 58.25 27 262 33642.44 57.08 27 262 424 46.4 4.37 HVO_2013 "FtsZ family protein, type III" 58.38 1 13 13 167 1.441E8 191.66 58.38 13 81 9179.79 58.38 13 86 394 41.5 4.61 HVO_2849 probable PrkA-type serine/threonine protein kinase 58.26 1 30 30 183 1.097E8 197.76 56.52 29 89 10323.93 58.26 30 94 690 79.9 4.79 HVO_0167 adenosylhomocysteinase 57.94 1 18 18 206 2.200E8 196.16 53.74 17 96 13371.00 57.94 18 110 428 46.6 4.39 HVO_0812 phosphoenolpyruvate synthase 57.82 1 39 39 794 2.567E9 904.93 53.09 36 393 44446.83 57.82 39 401 761 83.1 4.63 HVO_0083 GlnK-type ammonia transport regulator 57.72 1 3 4 36 6.328E7 29.67 34.96 3 16 2313.26 57.72 4 20 123 12.9 5.01 HVO_1189 aldehyde dehydrogenase 57.28 1 25 25 481 9.406E8 297.10 48.43 23 228 20138.56 57.28 25 253 508 56.1 4.59 HVO_1506 ketol-acid reductoisomerase 57.18 1 13 13 171 2.499E8 161.85 52.87 11 75 8808.30 57.18 13 96 348 37.9 4.34 HVO_0035 stomatin family protein 57.11 1 12 18 101 6.958E8 121.63 56.86 17 51 5786.31 55.61 17 50 401 43.6 4.65 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 56.76 1 13 13 428 1.262E9 540.26 56.76 13 215 21180.71 56.76 13 213 377 39.2 4.18 HVO_2543 50S ribosomal protein L30 56.49 1 7 7 70 2.248E8 59.67 56.49 7 35 4210.62 56.49 7 35 154 17.1 4.77 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 56.40 1 14 14 77 2.403E8 89.86 56.40 14 39 4598.31 56.40 14 38 445 47.8 4.86 HVO_2163 ABC-type transport system ATP-binding protein (homolog to LolDCE lipoprotein release factor) 55.42 1 10 10 58 7.914E7 73.54 47.39 9 28 4114.84 55.42 10 30 249 26.7 6.90 HVO_2015 conserved hypothetical protein 55.36 1 12 12 269 1.546E9 290.12 55.36 12 134 16084.26 55.36 12 135 345 37.7 4.25 HVO_2487 aspartate-semialdehyde dehydrogenase 55.23 1 11 11 123 2.453E8 129.05 55.23 11 61 5301.05 55.23 11 62 344 36.6 4.41 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 55.13 1 10 10 286 1.298E9 287.71 55.13 10 143 14887.97 55.13 10 143 312 34.5 4.98 HVO_1799 geranylgeranyl reductase / dolichol omega-reductase 55.12 1 14 14 94 1.600E8 72.17 50.24 13 45 5693.05 55.12 14 49 410 45.4 4.75 HVO_0850 proteasome-activating nucleotidase 54.81 1 14 14 101 2.853E7 113.75 49.63 13 49 5993.53 54.81 14 52 405 45.6 4.60 HVO_1522 hexuronic acid methyltransferase AglP 54.39 1 13 13 59 9.779E7 58.34 54.39 13 30 3318.68 54.39 13 29 239 26.2 4.98 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 54.17 1 25 25 225 2.825E8 269.50 54.17 25 112 12121.85 54.17 25 113 624 67.6 4.27 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 53.88 1 24 24 233 1.768E8 291.59 51.94 23 115 14629.37 53.88 24 118 516 56.7 4.89 HVO_2923 proteasome alpha subunit 53.82 1 10 11 72 3.316E8 75.80 53.82 11 36 4113.26 53.82 11 36 249 26.7 4.39 HVO_2777 30S ribosomal protein S9 53.79 1 7 7 33 6.040E7 35.39 49.24 6 16 1869.23 53.79 7 17 132 14.7 9.74 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 53.75 1 25 25 434 1.130E9 503.69 53.75 25 216 25897.05 53.24 24 218 586 64.0 4.49 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 53.66 1 25 25 387 6.653E8 441.67 53.66 25 193 21100.66 52.03 24 194 615 67.6 4.88 HVO_2413 translation elongation factor aEF-1 alpha subunit 53.33 1 13 16 255 1.333E8 116.32 51.90 15 101 10938.68 53.33 16 154 420 45.6 4.75 HVO_2774 enolase 53.13 1 14 14 179 8.681E8 183.35 53.13 14 92 9485.51 51.88 13 87 399 42.0 4.37 HVO_2889 RecJ domain protein 52.95 1 27 27 294 2.878E8 357.82 52.95 27 149 18619.52 52.95 27 145 729 79.1 4.37 HVO_1552 ArsR family transcription regulator 52.91 1 6 6 26 3.484E7 31.61 43.69 5 12 1549.76 52.91 6 14 206 20.8 4.65 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 52.86 1 13 13 115 1.878E8 118.62 52.86 13 57 6998.42 52.86 13 58 384 41.4 4.41 HVO_2547 50S ribosomal protein L32e 52.77 1 9 10 250 1.293E9 305.17 45.53 9 119 16481.23 52.77 10 131 235 25.8 4.75 HVO_2784 30S ribosomal protein S13 52.69 1 7 7 49 4.228E8 51.15 42.51 6 23 3144.48 52.69 7 26 167 18.9 5.17 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 52.68 1 18 18 116 2.810E8 130.98 52.68 18 57 6492.11 52.68 18 59 336 38.0 4.61 HVO_2588 isocitrate dehydrogenase (NADP) 52.51 1 19 19 164 3.298E8 164.62 49.40 18 82 8779.46 52.51 19 82 419 45.8 4.59 HVO_2559 50S ribosomal protein L22 52.29 1 5 5 24 2.797E7 31.72 29.41 3 10 2168.33 52.29 5 14 153 16.9 5.60 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 52.21 1 11 11 40 2.469E7 29.90 46.46 10 19 1985.91 52.21 11 21 226 25.5 4.25 HVO_A0301 polysaccharide deacetylase family protein 52.17 1 14 14 129 3.198E8 118.85 52.17 14 64 7167.81 52.17 14 65 299 34.2 4.56 HVO_1507 acetolactate synthase small subunit 51.83 1 11 11 46 2.377E7 57.37 51.83 10 22 2874.51 51.83 11 24 218 23.7 4.94 HVO_A0428 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 51.68 1 22 22 148 1.134E8 160.82 44.80 21 74 9021.02 51.68 22 74 567 62.4 4.70 HVO_1690 DHH family phosphoesterase 51.55 1 13 13 97 5.509E7 107.76 51.55 13 47 5619.80 51.55 13 50 485 52.1 4.48 HVO_2968 phosphoglycerate dehydrogenase 51.43 1 17 17 179 3.677E8 237.86 51.43 17 90 11745.78 51.43 17 89 525 55.3 4.36 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 50.93 1 12 12 84 1.067E8 84.06 50.93 12 41 5559.11 50.93 12 43 324 36.6 4.68 HVO_A0133 conserved hypothetical protein 50.68 1 14 14 248 8.469E8 328.48 48.97 13 123 15045.80 48.97 13 125 292 30.8 5.17 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 50.44 1 25 25 490 1.270E9 572.24 50.44 25 246 27161.62 50.44 25 244 573 62.9 4.45 HVO_1091 proteasome alpha subunit 50.40 1 13 14 232 1.011E9 251.50 50.40 14 115 14004.30 50.40 14 117 252 27.6 4.56 HVO_0055 CBS domain protein 50.35 1 10 10 45 3.378E7 49.85 50.35 10 22 2738.10 50.35 10 23 284 30.8 4.27 HVO_0446 ABC-type transport system ATP-binding protein (probable substrate phosphate/phosphonate) 50.19 1 9 9 50 4.678E7 44.63 46.44 8 22 2817.31 50.19 9 28 267 28.9 4.64 HVO_2782 30S ribosomal protein S11 50.00 1 6 6 35 3.937E7 33.87 50.00 6 18 1771.68 50.00 6 17 130 13.4 8.56 HVO_2778 50S ribosomal protein L13 49.66 1 5 5 32 5.705E7 46.53 49.66 5 16 2081.76 49.66 5 16 145 16.0 5.43 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 49.48 1 6 6 52 1.242E8 37.78 38.66 5 20 4386.01 49.48 6 32 194 20.7 4.12 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 49.43 1 9 9 34 6.080E7 47.43 47.92 8 16 2471.79 49.43 9 18 265 29.3 4.92 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 48.81 1 20 20 473 2.624E9 501.12 47.54 19 242 25838.09 44.85 19 231 631 68.4 4.49 HVO_0869 glutamate synthase large subunit 48.64 1 55 56 401 1.370E8 438.23 48.64 56 198 24759.30 48.64 56 203 1511 163.8 4.70 HVO_1673 conserved hypothetical protein 48.61 1 8 8 64 1.485E8 76.32 48.61 8 32 4059.48 48.61 8 32 216 23.2 4.58 HVO_2436 malic enzyme (NADP) 48.60 1 20 25 279 4.370E8 357.23 47.54 24 137 17326.86 48.60 25 142 751 81.4 4.55 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 47.74 1 14 14 168 6.638E8 209.83 47.74 14 82 10668.61 47.74 14 86 398 43.4 4.37 HVO_1082 homolog to orotate phosphoribosyltransferase 47.62 1 7 7 29 4.858E7 31.12 36.67 6 14 1790.66 47.62 7 15 210 22.3 4.42 HVO_2606 PQQ repeat protein 47.60 1 16 17 111 1.870E8 90.89 46.45 16 56 5397.17 42.33 16 55 437 46.9 4.81 HVO_0348 DNA-directed RNA polymerase subunit B' 47.45 1 20 20 100 6.617E7 131.99 47.45 20 52 5113.71 46.63 19 48 609 67.7 4.92 HVO_1568 alpha/beta hydrolase fold protein 47.29 1 9 9 45 4.916E7 55.18 47.29 9 23 2553.38 41.52 8 22 277 29.4 4.94 HVO_1130 conserved hypothetical protein 47.15 1 5 5 38 4.781E7 29.53 47.15 5 19 1610.71 35.75 4 19 193 20.1 4.78 HVO_0806 pyruvate kinase 47.01 1 18 18 204 3.769E8 201.06 47.01 18 99 11070.08 47.01 18 105 585 62.0 4.54 HVO_2947 phenylalanine--tRNA ligase beta subunit 46.84 1 18 18 128 2.109E8 101.09 44.74 16 61 7111.90 46.84 18 67 570 63.3 4.46 HVO_1987 signal peptide peptidase 46.82 1 8 8 73 2.639E8 81.11 46.82 8 37 4312.64 46.82 8 36 299 31.3 4.56 HVO_0393 UvrABC system protein A 46.80 1 33 33 139 3.750E7 140.77 46.80 33 68 7001.46 46.80 33 71 983 108.6 4.82 HVO_1684 threonine--tRNA ligase 46.50 1 26 26 156 2.489E8 168.06 42.30 23 74 9754.63 46.50 26 82 643 73.4 4.45 HVO_2555 30S ribosomal protein S17 46.49 1 4 4 30 6.136E7 32.33 46.49 4 15 1669.63 46.49 4 15 114 12.7 4.81 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 101 3.122E8 128.19 43.25 7 48 6595.64 46.37 8 53 289 29.8 4.27 HVO_1578 probable NADH dehydrogenase 46.35 1 20 20 368 9.151E8 520.08 46.35 20 184 26184.27 46.35 20 184 397 42.8 4.40 HVO_2538 alpha/beta hydrolase fold protein 46.33 1 11 11 88 1.932E8 90.23 46.01 10 43 5198.37 46.33 11 45 313 33.8 6.06 HVO_0880 conserved hypothetical protein 46.25 1 12 12 28 1.175E7 14.57 43.97 10 13 1281.12 46.25 12 15 307 36.3 4.74 HVO_0087 porphobilinogen synthase 46.18 1 10 10 71 9.996E7 71.78 46.18 10 35 3830.60 46.18 10 36 327 35.3 4.72 HVO_3007 malate dehydrogenase 46.05 1 12 12 75 3.244E8 80.03 46.05 12 36 3441.07 46.05 12 39 304 32.6 4.40 HVO_A0619 conserved hypothetical protein 46.02 1 14 14 105 8.536E7 77.01 46.02 14 52 4922.88 46.02 14 53 452 48.2 4.68 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 45.93 1 12 12 152 4.736E8 191.60 45.93 12 77 9450.72 45.93 12 75 381 41.0 4.23 HVO_0829 peptidase S9 family protein 45.89 1 17 17 104 8.379E7 103.57 45.89 17 51 5710.14 45.89 17 53 608 67.4 4.54 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 45.86 1 19 19 186 2.153E8 198.77 45.86 19 91 9844.73 45.86 19 95 471 51.0 4.48 HVO_0861 SufB domain protein 45.77 1 15 15 87 1.593E8 112.64 42.29 14 43 6113.92 45.77 15 44 402 44.7 4.23 HVO_0860 SufB domain protein 45.59 1 16 16 119 2.293E8 118.33 41.81 14 59 6882.12 45.59 16 60 476 53.2 4.69 HVO_2848 probable PrkA-type serine/threonine protein kinase 45.44 1 23 23 109 5.855E7 112.74 45.44 23 56 5836.57 41.61 21 53 757 85.3 4.67 HVO_1020 HEAT-PBS family protein 45.35 1 16 16 256 5.407E8 288.22 41.05 15 119 17121.36 45.35 16 137 419 45.5 3.95 HVO_2646 dihydroxy-acid dehydratase 45.21 1 14 14 132 2.387E8 152.54 38.01 13 66 9016.55 45.21 14 66 584 61.8 4.42 HVO_1348 probable YjeF family carbohydrate kinase 45.19 1 17 17 170 2.356E8 222.65 45.19 17 85 11212.20 45.19 16 85 478 48.8 4.45 HVO_0025 thiosulfate sulfurtransferase 45.10 1 8 8 41 1.344E8 25.12 42.66 7 19 2076.12 45.10 8 22 286 32.1 4.28 HVO_1590 DnaK-type molecular chaperone Hsp70 44.96 1 22 22 214 6.614E8 244.98 44.96 22 107 10953.85 42.56 21 107 625 67.2 4.18 HVO_1132 adenylosuccinate synthase 44.92 1 19 19 177 1.495E8 179.86 41.31 17 86 10962.63 44.92 19 91 443 48.2 4.56 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 44.85 1 11 11 79 3.795E7 46.44 44.85 11 39 3820.94 44.85 11 40 330 36.3 4.35 HVO_0314 A-type ATP synthase subunit C 44.83 1 13 13 110 1.732E8 150.01 40.80 12 52 8449.12 44.83 13 58 348 38.7 4.50 HVO_2621 phosphoenolpyruvate carboxylase 44.59 1 30 30 196 1.554E8 212.94 44.59 30 98 10371.50 44.59 30 98 897 102.3 4.64 HVO_2562 50S ribosomal protein L23 44.58 1 4 4 51 6.811E7 62.96 31.33 3 23 4137.03 44.58 4 28 83 9.4 5.48 HVO_2700 AAA-type ATPase (CDC48 subfamily) 44.56 1 25 26 121 4.753E7 122.41 44.43 25 60 6195.71 44.56 26 61 754 82.8 4.75 HVO_0085 GlnK-type ammonia transport regulator 44.54 1 3 4 71 3.324E8 67.59 44.54 4 35 4722.40 44.54 4 36 119 12.5 4.97 HVO_0745 "FtsZ family protein, type III" 44.44 1 9 10 45 4.799E7 51.89 44.44 10 23 2465.71 39.72 9 22 360 37.1 4.51 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 44.43 1 29 29 346 5.504E8 374.17 44.43 28 169 19431.06 44.43 29 177 898 97.7 4.45 HVO_0349 DNA-directed RNA polymerase subunit A' 44.36 1 31 31 370 3.677E8 388.46 43.24 29 183 22629.41 40.78 30 187 976 108.8 4.81 HVO_A0295 amidase (hydantoinase/carbamoylase family) 44.15 1 15 15 84 1.250E8 111.62 38.54 14 42 5608.88 44.15 15 42 410 45.0 4.30 HVO_C0074 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 43.91 1 20 20 82 5.035E7 76.55 43.91 20 41 4287.27 43.91 20 41 690 75.9 4.79 HVO_2168 AAA-type ATPase (MoxR subfamily) 43.77 1 11 11 59 8.581E7 66.47 43.77 11 29 3453.93 43.77 11 30 329 35.9 4.54 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 43.55 1 11 11 106 1.122E8 95.63 43.55 11 52 4770.62 43.55 11 54 473 50.8 4.58 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 43.33 1 13 13 59 3.438E7 55.10 43.33 13 29 2812.22 43.33 13 30 457 48.4 4.35 HVO_0347 DNA-directed RNA polymerase subunit B'' 43.19 1 17 17 104 6.965E7 114.74 43.19 17 52 5286.89 43.19 17 52 521 58.9 5.00 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 43.18 1 19 20 121 1.052E8 93.54 38.52 19 59 5887.53 41.73 19 62 623 62.1 5.30 HVO_0118 50S ribosomal protein L20e 43.10 1 2 2 12 3.156E7 8.99 43.10 2 6 708.14 43.10 2 6 58 6.4 6.52 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 43.03 1 10 10 1919 7.171E8 2689.96 43.03 10 959 92014.46 43.03 10 960 574 62.8 4.17 HVO_2519 conserved hypothetical protein 42.93 1 13 13 92 8.037E7 129.01 38.22 12 43 7161.59 42.93 13 49 382 40.7 4.35 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 42.90 1 13 13 65 6.363E7 66.64 40.58 12 33 2900.94 39.13 11 32 345 36.9 4.68 HVO_1084 adenylosuccinate lyase 42.76 1 14 14 75 9.937E7 85.83 41.68 13 36 4302.98 42.76 14 39 463 50.8 4.70 HVO_2204 "FtsZ family protein, type III" 42.28 1 13 14 198 3.566E8 219.87 42.28 14 98 12464.61 42.28 14 100 395 42.0 4.68 HVO_B0134 ABC-type transport system ATP-binding protein 42.25 1 7 7 84 1.475E8 84.75 42.25 7 41 4697.98 42.25 7 43 258 27.2 4.53 HVO_1711 glucoamylase 42.09 1 45 45 228 1.664E8 256.44 40.64 44 112 14298.67 42.09 45 116 1511 166.1 4.64 HVO_0484 50S ribosomal protein L10e 42.05 1 8 8 85 6.266E8 80.31 41.48 7 41 4582.67 42.05 8 44 176 19.8 8.72 HVO_2561 50S ribosomal protein L2 41.91 1 13 13 325 1.382E9 382.68 41.91 13 161 21618.04 39.83 12 164 241 25.6 10.40 HVO_0206 alanine--tRNA ligase 41.87 1 26 26 156 4.414E7 150.52 41.00 25 76 8330.28 37.74 25 80 922 102.4 4.54 HVO_1571 DNA topoisomerase VI subunit B 41.73 1 23 23 161 2.113E8 167.56 34.96 19 78 9111.46 41.73 23 83 798 87.4 4.73 HVO_0122 phosphoglycerate dehydrogenase 41.67 1 9 9 56 6.296E7 65.52 34.57 8 27 3666.68 41.67 9 29 324 35.3 5.35 HVO_2425 GNAT family acetyltransferase 41.67 1 7 7 51 8.529E7 41.60 41.67 7 25 2494.15 41.67 7 26 216 24.4 4.54 HVO_2481 HD family hydrolase 41.54 1 10 12 46 2.377E7 37.99 41.54 12 23 2095.56 41.54 12 23 390 42.7 6.14 HVO_2948 phenylalanine--tRNA ligase alpha subunit 41.48 1 10 10 122 1.360E8 160.01 41.48 10 62 7802.11 40.48 9 60 499 55.1 4.41 HVO_2467 NADPH:quinone reductase 41.43 1 7 7 33 2.673E7 41.00 29.91 6 16 1788.97 41.43 7 17 321 33.0 4.51 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 41.40 1 10 10 46 3.850E7 58.17 41.40 10 23 2492.10 41.40 10 23 343 38.4 4.94 HVO_2708 YfiH family protein 40.99 1 8 8 45 8.479E7 41.56 40.99 8 21 2434.95 40.99 8 24 322 35.4 4.35 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 40.98 1 8 8 31 3.122E7 25.53 40.98 8 16 1387.42 37.70 7 15 305 32.7 4.56 HVO_0316 A-type ATP synthase subunit A 40.96 1 20 20 312 9.375E8 392.68 40.96 20 158 19610.58 40.10 19 154 586 64.5 4.25 HVO_0161 ATP phosphoribosyltransferase 40.93 1 9 9 38 2.144E7 43.51 36.65 8 19 2478.41 37.01 8 19 281 30.4 4.60 HVO_A0350 conserved hypothetical protein 40.85 1 8 8 56 1.396E8 55.00 40.85 8 29 2610.22 40.85 8 27 213 23.8 9.64 17318569 keratin 1 [Homo sapiens] 40.84 1 2 29 287 3.133E8 348.00 39.91 28 144 19450.67 40.84 29 143 644 66.0 8.12 HVO_2153 probable copper-containing oxidoreductase 40.78 1 12 12 85 1.159E8 95.12 40.78 11 41 5302.44 40.78 12 44 385 42.1 5.82 HVO_0979 NADH dehydrogenase-like complex subunit B 40.77 1 8 8 49 1.579E8 55.58 32.62 7 23 3159.69 40.77 8 26 233 26.1 5.01 HVO_0999 DRTGG domain protein 40.74 1 10 10 41 4.367E7 45.66 40.74 10 20 2126.34 40.74 10 21 378 39.8 4.44 HVO_0117 translation initiation factor aIF-6 40.72 1 6 6 40 1.035E8 56.42 40.72 6 20 2611.93 40.72 6 20 221 23.0 4.27 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 40.72 1 12 12 62 3.736E7 77.23 40.72 12 31 3968.76 40.72 12 31 442 46.9 4.58 HVO_0773 probable S-adenosylmethionine-dependent methyltransferase 40.64 1 9 9 50 6.984E7 50.92 40.64 9 25 3050.85 40.64 9 25 251 27.8 6.06 HVO_2046 sulfatase domain protein 40.49 1 14 14 79 1.346E8 59.04 40.49 13 39 3796.80 40.49 14 40 405 45.5 4.87 HVO_1502 3-isopropylmalate dehydrogenase 40.43 1 9 9 40 6.490E7 39.82 32.72 8 16 2511.62 40.43 9 24 324 33.7 4.23 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 40.41 1 8 8 35 6.677E7 27.08 40.41 8 17 1572.12 40.41 8 18 386 42.1 4.49 HVO_0718 protein translocase subunit SecE 40.35 1 2 2 8 1.714E7 8.28 40.35 2 4 328.11 40.35 2 4 57 6.2 8.62 HVO_2960 dihydrolipoamide S-acyltransferase 40.31 1 21 21 189 2.659E8 235.15 38.96 20 93 11691.52 40.31 21 96 521 54.9 4.40 HVO_0233 ribose-phosphate pyrophosphokinase 40.28 1 6 6 36 2.644E7 48.96 40.28 6 18 2127.77 40.28 6 18 283 29.6 4.40 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 40.22 1 5 5 20 3.529E7 27.20 40.22 5 10 1448.00 40.22 5 10 184 19.8 5.30 HVO_0433 F420H2:NADP oxidoreductase 40.09 1 5 5 30 1.648E7 37.38 40.09 5 15 1894.09 40.09 5 15 222 23.3 4.72 HVO_2549 30S ribosomal protein S8 40.00 1 4 4 16 2.693E7 14.54 40.00 4 8 793.15 40.00 4 8 130 14.1 4.79 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 39.72 1 11 11 43 4.329E7 31.57 39.72 11 21 1813.08 39.72 11 22 360 39.6 4.39 HVO_1134 conserved hypothetical protein 39.63 1 19 19 119 7.063E7 113.69 39.63 19 59 6395.27 37.12 18 60 757 80.6 4.35 HVO_A0304 homolog to thermosome 39.49 1 18 18 92 7.741E7 99.36 39.49 18 46 5038.38 39.49 18 46 590 61.9 4.78 HVO_2384 CBS domain protein 39.47 1 9 10 78 3.127E8 96.38 38.16 9 39 5158.72 39.47 10 39 380 42.5 5.01 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 39.44 1 0 27 279 3.133E8 336.75 38.51 26 140 18959.71 39.44 27 139 644 66.0 8.12 HVO_A0293 ABC-type transport system ATP-binding protein (probable substrate spermidine/putrescine) 39.43 1 14 14 111 1.884E8 129.91 39.43 14 55 6651.74 39.43 14 56 383 42.3 4.39 HVO_2542 50S ribosomal protein L15 39.39 1 7 7 126 2.230E8 173.33 39.39 7 63 8135.51 39.39 7 63 165 17.8 4.93 HVO_0870 proline--tRNA ligase 39.34 1 12 12 77 4.787E7 77.65 36.89 11 38 4605.77 39.34 12 39 488 54.9 4.44 HVO_2534 UspA domain protein 39.10 1 3 3 12 1.020E7 6.57 39.10 3 6 433.70 39.10 3 6 133 14.3 4.58 HVO_1967 glucose-6-phosphate isomerase 39.07 1 10 10 68 8.790E7 93.95 39.07 10 34 4759.69 39.07 10 34 430 45.6 4.40 HVO_2533 conserved hypothetical protein 38.99 1 7 7 82 1.358E8 117.55 38.99 7 42 5386.19 38.99 7 40 336 35.1 4.39 HVO_2553 50S ribosomal protein L24 38.98 1 4 4 24 6.607E7 16.52 38.98 4 11 1243.81 38.98 4 13 118 13.4 4.73 HVO_2053 "probable glycosyltransferase, type 1" 38.89 1 12 12 81 1.366E8 100.93 38.89 12 41 5044.78 38.89 12 40 378 41.9 4.67 HVO_1545 dihydroxyacetone kinase subunit DhaL 38.79 1 6 7 26 2.058E7 30.35 38.79 7 13 1521.77 38.79 7 13 232 24.8 4.48 HVO_1327 AAA-type ATPase (CDC48 subfamily) 38.72 1 16 17 89 2.057E7 87.73 38.72 17 43 3924.68 38.72 17 46 736 78.1 4.88 HVO_1306 chorismate synthase 38.70 1 11 11 67 1.041E8 87.78 38.70 11 34 4019.64 38.70 10 33 385 41.9 4.83 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 38.70 1 13 13 107 1.483E8 114.23 37.36 12 53 5993.81 38.70 13 54 447 48.5 4.56 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 38.67 1 12 12 72 7.410E7 70.02 36.76 11 35 3864.00 38.67 12 37 525 56.4 4.40 HVO_3002 ABC-type transport system ATP-binding protein 38.65 1 11 11 122 1.224E8 131.24 35.58 10 60 6723.76 38.65 11 62 326 34.7 4.31 HVO_2554 50S ribosomal protein L14 38.64 1 6 6 92 5.544E8 114.31 38.64 6 46 4952.28 38.64 6 46 132 14.2 9.76 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 38.24 1 14 14 288 1.799E9 309.09 38.24 14 143 15997.90 38.24 14 145 612 67.3 4.16 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 38.22 1 7 7 23 3.016E7 32.27 33.59 6 11 1626.85 38.22 7 12 259 28.0 4.50 HVO_B0194 conserved hypothetical protein 38.07 1 9 9 54 5.000E7 56.95 38.07 9 27 2405.78 30.20 8 27 394 42.7 5.35 HVO_1465 naphthoate synthase 38.03 1 10 10 88 4.898E7 100.54 35.08 9 44 5282.85 38.03 10 44 305 33.9 4.83 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 37.97 1 8 8 58 1.743E8 67.11 37.97 8 29 3504.95 37.97 8 29 266 27.8 4.84 HVO_0908 conserved hypothetical protein 37.82 1 2 2 12 3.293E7 11.30 37.82 2 6 353.71 37.82 2 6 119 12.6 4.22 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 37.72 1 7 7 36 3.568E7 49.15 37.72 7 18 2296.49 37.72 7 18 281 30.6 4.59 HVO_1550 acyl-CoA thioester hydrolase 37.50 1 4 4 17 1.979E7 10.68 30.63 3 6 1016.66 37.50 4 11 160 17.6 4.55 HVO_A0049 DUF21/CBS domain protein 37.50 1 11 11 55 6.064E7 70.03 31.92 10 27 3364.67 37.50 11 28 448 48.8 4.31 HVO_1957 proteasome-activating nucleotidase 37.38 1 10 10 42 1.551E7 39.25 37.38 10 22 1986.97 34.47 9 20 412 45.6 4.48 HVO_0826 peptidase M42 family protein 37.36 1 8 8 44 5.299E7 45.21 37.36 8 22 1939.61 37.36 8 22 348 37.7 4.54 HVO_1488 D-gluconate dehydratase 36.89 1 10 13 166 1.153E9 181.99 36.89 13 83 10386.43 36.89 13 83 412 45.8 4.60 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 36.81 1 10 10 79 9.841E7 88.27 32.42 8 39 5162.12 36.81 10 40 364 39.3 4.35 HVO_1563 conserved hypothetical protein 36.80 1 4 4 20 4.404E7 24.02 36.80 4 10 1484.17 36.80 4 10 125 13.8 11.02 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 36.77 1 10 10 46 7.510E7 48.00 33.70 9 23 2672.53 36.77 10 23 359 39.4 4.91 HVO_1453 glutamate dehydrogenase (NADP) 36.69 1 12 12 87 8.597E7 85.61 29.50 10 41 4871.54 36.69 12 46 417 45.7 4.49 40354192 keratin 10 [Homo sapiens] 36.64 1 0 21 166 2.191E8 172.74 36.64 21 83 8992.52 36.64 21 83 584 58.8 5.16 HVO_1570 DNA topoisomerase VI subunit A 36.61 1 9 9 43 9.464E7 54.46 33.88 8 20 3240.58 36.61 9 23 366 41.8 4.63 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 36.59 1 29 29 221 1.313E8 234.33 34.46 26 108 12779.43 35.33 28 113 1033 114.3 4.45 HVO_A0034 conserved hypothetical protein 36.36 1 2 2 2 1.458E7 0.00 36.36 2 2 121 13.9 8.82 HVO_1697 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 36.35 1 31 34 241 2.430E8 259.75 35.38 32 120 14326.23 33.43 33 121 1026 111.2 4.54 HVO_1018 RecJ domain protein 36.33 1 21 21 168 1.847E8 162.77 34.91 20 83 9579.23 36.33 21 85 633 69.8 4.58 HVO_A0039 hypothetical protein 36.20 1 8 8 95 7.390E8 146.78 36.20 8 47 7629.27 25.15 7 48 326 35.6 4.60 HVO_2643 NADPH:quinone reductase 36.13 1 10 10 70 5.248E7 40.09 36.13 10 35 3734.19 36.13 10 35 346 37.2 4.55 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 36.09 1 0 21 166 2.191E8 172.74 36.09 21 83 8992.52 36.09 21 83 593 59.5 5.21 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 36.08 1 12 12 50 3.282E7 52.88 36.08 12 24 2584.74 36.08 12 26 474 53.4 4.59 HVO_2123 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 36.03 1 9 9 48 6.418E7 51.35 32.40 8 23 2514.27 33.80 8 25 358 38.8 4.61 HVO_A0156 acyl-CoA synthetase 35.84 1 6 14 98 1.385E8 114.17 35.84 14 50 5590.96 35.84 14 48 664 74.0 4.40 HVO_1955 aconitate hydratase 35.78 1 15 15 212 4.675E8 259.71 35.78 15 104 13769.15 35.78 15 108 654 70.4 4.45 HVO_2552 30S ribosomal protein S4e 35.63 1 7 7 36 1.531E8 42.63 35.63 7 18 2282.95 35.63 7 18 247 26.6 4.58 HVO_0058 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 35.59 1 10 10 42 5.854E7 53.27 35.59 10 23 2492.95 26.58 9 19 444 50.2 4.84 HVO_0783 ATP-dependent protease La 35.59 1 14 14 62 7.057E7 63.44 35.59 14 31 3278.59 31.27 13 31 694 75.4 4.86 HVO_1577 conserved hypothetical protein 35.59 1 5 5 23 2.262E7 32.33 29.94 4 11 1637.61 35.59 5 12 177 19.4 4.74 HVO_2961 dihydrolipoyl dehydrogenase 35.58 1 10 10 56 3.947E7 61.86 35.58 10 28 2604.80 35.58 10 28 475 49.9 4.41 HVO_2070 conserved hypothetical protein 35.48 1 13 13 322 7.634E8 420.39 35.48 13 165 19521.72 35.29 12 157 544 58.1 4.50 HVO_1242 conserved hypothetical protein 35.42 1 12 12 62 3.709E7 71.22 35.42 12 31 3113.79 35.42 12 31 432 47.1 4.75 HVO_1212 KaiC-type circadian regulator CirA 35.37 1 7 7 44 7.993E7 63.45 35.37 7 22 2914.65 35.37 7 22 246 27.5 4.45 HVO_2040 NAD-dependent epimerase/dehydratase 35.29 1 5 9 67 2.627E7 45.41 35.29 9 33 3632.77 35.29 9 34 306 33.8 4.51 HVO_2225 AstE family protein 35.19 1 7 7 52 7.411E7 52.97 35.19 7 26 2505.69 35.19 7 26 341 36.9 4.53 HVO_1575 arginase 35.12 1 6 6 22 2.515E7 15.26 31.77 5 11 864.74 35.12 6 11 299 31.0 4.58 HVO_2813 RimK family protein 35.10 1 11 11 92 7.301E7 114.24 35.10 11 46 5842.08 35.10 11 46 453 49.0 4.73 HVO_1593 PAC2 family protein 35.08 1 5 5 18 2.197E7 27.59 35.08 5 9 1086.70 35.08 5 9 248 26.6 4.46 HVO_0743 probable phosphodiesterase 34.97 1 14 14 82 8.307E7 55.64 34.97 14 42 4280.32 30.51 12 40 449 50.5 4.56 HVO_0859 FeS assembly ATPase SufC 34.88 1 9 9 102 1.132E8 100.60 34.88 9 51 5852.87 34.88 9 51 301 33.4 4.35 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 34.86 1 11 11 63 1.333E8 63.08 31.19 10 30 3687.23 34.86 11 33 327 36.0 4.73 HVO_B0093 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 34.63 1 13 13 60 4.367E7 73.13 33.82 12 29 2838.49 34.63 13 31 618 69.1 4.45 HVO_1172 NAD-dependent epimerase/dehydratase 34.60 1 6 6 18 4.285E7 23.99 21.27 5 8 1286.13 34.60 6 10 315 34.9 4.34 HVO_A0406 conserved hypothetical protein 34.57 1 1 9 35 1.950E7 44.51 34.57 9 17 2304.26 34.57 9 18 405 44.4 5.30 HVO_2048 "probable glycosyltransferase, type 1" 34.54 1 11 11 60 8.366E7 66.32 34.54 11 30 3432.34 34.54 11 30 359 40.5 5.30 HVO_2008 archaeosine synthase 34.53 1 15 15 73 1.363E8 72.84 31.28 13 35 3669.05 33.50 14 38 585 64.9 4.81 HVO_2801 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 34.49 1 7 7 78 6.465E7 92.08 34.49 7 39 3193.54 34.49 7 39 287 31.4 4.48 HVO_0729 inorganic pyrophosphatase 34.46 1 7 7 54 1.461E8 51.25 34.46 7 28 3025.65 34.46 7 26 177 20.4 4.16 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 34.44 1 11 11 51 5.849E7 52.47 34.44 11 25 2761.84 34.44 11 26 453 47.5 4.63 HVO_A0589 HxlR family transcription regulator 34.43 1 2 2 2 1.588E6 64.36 34.43 2 2 122 13.8 4.48 HVO_1824 conserved hypothetical protein 34.27 1 11 11 49 6.239E7 60.40 33.33 9 24 3342.97 28.67 10 25 429 47.4 4.20 HVO_1871 UPF0447 family protein 34.13 1 13 13 168 5.796E8 130.25 29.34 11 79 8970.05 34.13 13 89 501 56.1 4.59 HVO_1508 acetolactate synthase large subunit 34.07 1 11 11 123 1.070E8 150.51 34.07 11 61 7319.33 34.07 11 62 587 62.3 4.36 HVO_1447 propionyl-CoA carboxylase carboxyltransferase component 33.91 1 14 14 59 2.891E7 67.78 32.87 13 29 3776.86 27.71 12 30 581 63.6 4.70 HVO_2620 cytochrome bc1 complex Rieske iron-sulfur protein 33.81 1 4 4 109 3.398E8 143.26 33.81 4 55 6505.78 33.81 4 54 281 30.2 4.31 HVO_2809 succinate dehydrogenase subunit B (iron-sulfur protein) 33.79 1 12 12 100 2.219E8 53.47 33.79 12 48 4534.93 33.79 12 52 293 33.9 5.27 HVO_2624 CTP synthase 33.70 1 13 13 64 5.941E7 35.82 30.05 11 28 3778.95 33.70 13 36 549 60.8 4.70 47132620 keratin 2a [Homo sapiens] 33.65 1 13 19 110 1.958E8 125.38 33.65 19 55 6770.78 33.65 19 55 639 65.4 8.00 HVO_0104 DNA repair and recombination protein RadA 33.53 1 8 8 37 6.664E7 36.63 28.28 7 17 2770.90 33.53 8 20 343 37.3 4.64 HVO_2068 "FtsZ family protein, type III" 33.51 1 8 8 43 4.513E7 60.07 33.51 8 22 2900.85 33.51 8 21 370 38.7 4.49 HVO_0854 DNA double-strand break repair ATPase Rad50 33.48 1 23 23 76 2.400E7 76.61 33.48 23 38 3721.83 32.03 22 38 893 100.0 4.58 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 33.45 1 13 13 66 7.358E7 67.19 33.45 13 33 3353.49 33.45 13 33 592 66.6 4.61 HVO_2675 histidinol dehydrogenase 33.41 1 9 9 62 2.352E7 67.89 33.41 9 31 2939.56 33.41 9 31 428 45.4 4.50 HVO_0809 methionine--tRNA ligase 33.38 1 18 18 116 8.629E7 138.85 32.70 17 58 7702.43 33.38 18 58 740 81.9 4.37 HVO_1443 ABC-type transport system ATP-binding protein 33.33 1 8 8 36 3.068E7 45.96 33.33 8 19 2089.90 31.21 7 17 330 36.3 4.70 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 33.33 1 6 6 216 6.194E8 281.15 33.33 6 108 13213.18 33.33 6 108 297 32.3 3.98 HVO_2969 threonine synthase 33.17 1 9 9 43 9.930E7 60.54 33.17 9 21 2903.54 33.17 9 22 419 44.4 4.49 HVO_1692 probable iron-sulfur protein (4Fe-4S) 33.15 1 19 19 178 3.855E8 176.07 33.15 19 89 9366.89 33.15 19 89 733 80.2 4.49 HVO_0041 ornithine carbamoyltransferase 33.11 1 6 6 21 1.658E7 22.16 33.11 6 11 1020.25 33.11 6 10 299 32.7 4.37 HVO_A0205 CRISPR-associated endoribonuclease Cas6 32.72 1 8 8 48 6.200E7 60.26 32.72 8 24 3247.48 32.72 8 24 272 31.0 5.44 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 32.71 1 7 7 84 2.197E8 119.11 32.71 7 42 6054.89 32.71 7 42 431 46.1 4.48 HVO_1025 acetyl-CoA C-acyltransferase 32.64 1 9 9 45 5.610E7 55.97 32.64 9 22 2694.08 32.64 9 23 383 40.7 4.56 HVO_2049 "probable glycosyltransferase, type 2" 32.57 1 9 9 50 1.863E8 47.22 32.57 9 25 2559.63 32.57 9 25 307 35.3 5.40 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 32.52 1 6 6 33 3.679E7 18.79 19.93 5 16 1375.28 32.52 6 17 286 30.8 4.46 HVO_0402 DUF124 family protein 32.44 1 5 5 36 7.804E7 42.08 32.44 5 18 2023.48 32.44 5 18 225 24.0 4.58 HVO_0996 DUF21/CBS domain protein 32.43 1 10 10 44 4.206E7 50.92 30.25 9 22 2513.95 32.43 10 22 367 39.1 4.51 HVO_2191 formyltetrahydrofolate deformylase 32.42 1 8 8 34 3.644E7 40.80 32.42 8 17 2137.69 32.42 8 17 327 36.2 4.63 HVO_2958 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit 32.34 1 7 7 43 1.861E7 43.63 32.34 7 21 2015.01 32.34 7 22 368 40.9 4.68 HVO_1006 ABC-type transport system ATP-binding protein 32.18 1 5 5 20 2.623E7 24.49 32.18 5 10 1034.60 32.18 5 10 317 32.7 4.39 HVO_1603 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfonate) 32.18 1 5 5 39 9.935E7 43.25 32.18 5 19 1655.30 32.18 5 20 348 37.2 4.35 HVO_A0496 UspA domain protein 32.07 1 7 7 32 4.170E7 34.70 32.07 7 16 1638.57 32.07 7 16 290 31.4 4.60 HVO_2783 30S ribosomal protein S4 32.00 1 5 5 22 2.067E7 13.68 32.00 5 10 1321.03 32.00 5 12 175 20.1 5.24 HVO_0354 30S ribosomal protein S7 31.86 1 4 4 18 2.327E7 21.43 31.86 4 9 1066.41 31.86 4 9 204 22.6 5.14 HVO_B0118 SMC-like protein Sph2 31.83 1 17 17 93 8.511E7 98.54 31.83 16 45 5782.92 31.83 17 48 644 73.8 4.41 HVO_2430 ABC-type transport system ATP-binding protein (probable substrate glutamine) 31.82 1 6 6 45 6.790E7 56.65 31.82 6 23 2722.57 31.82 6 22 242 26.6 4.88 HVO_A0206 CRISPR-associated protein Cas8b 31.80 1 18 18 97 7.887E7 112.34 31.10 17 47 5718.88 31.80 18 50 717 79.3 4.60 HVO_C0069 GFO family oxidoreductase 31.79 1 7 7 51 2.559E7 56.03 31.79 7 25 2692.73 31.79 7 26 324 36.0 5.10 HVO_0307 conserved hypothetical protein 31.75 1 11 12 95 8.254E7 102.85 31.75 12 47 4793.86 30.02 11 48 463 49.0 4.88 HVO_0449 prephenate dehydratase 31.72 1 5 5 19 2.695E7 22.00 31.72 5 10 787.23 25.37 4 9 268 28.7 4.64 HVO_1076 sugar nucleotidyltransferase 31.68 1 6 6 27 3.555E7 21.07 31.68 6 13 1370.15 31.68 6 14 322 35.8 4.20 HVO_1517 dolichyl-phosphate hexosyltransferase AglJ 31.68 1 6 6 23 9.203E7 20.86 31.68 6 12 1511.82 31.68 6 11 303 33.2 4.82 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 31.38 1 3 3 18 1.681E7 21.86 31.38 3 9 1055.32 31.38 3 9 188 20.5 4.60 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 31.34 1 3 3 8 7.389E6 9.51 31.34 3 4 520.44 31.34 3 4 134 13.9 4.55 HVO_1562 proteasome beta subunit 31.28 1 6 6 76 1.607E8 90.15 31.28 6 38 4412.73 31.28 6 38 243 26.0 4.63 HVO_2749 50S ribosomal protein L21e 31.25 1 3 3 7 5.825E6 0.00 20.83 2 3 301.96 31.25 3 4 96 10.6 10.95 HVO_2158 malic enzyme (NADP) 31.16 1 9 14 101 2.619E8 119.64 31.16 14 50 5937.54 31.16 14 51 751 81.4 4.55 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 31.13 1 18 18 106 1.043E8 89.64 23.24 15 49 6104.18 31.13 18 57 697 74.5 4.13 HVO_B0082 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 31.11 1 12 12 80 7.253E7 102.12 31.11 12 40 5265.07 31.11 12 40 569 62.8 4.30 HVO_0570 histidine kinase 31.05 1 8 8 52 2.201E7 52.26 31.05 8 26 2274.77 31.05 8 26 351 37.0 5.11 HVO_1495 "phosphotransferase system component IIB, fructose-specific" 31.01 1 2 2 8 1.755E7 11.72 31.01 2 4 520.68 31.01 2 4 158 16.3 4.46 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 30.93 1 9 9 99 2.319E8 89.58 30.93 9 48 5167.07 30.93 9 51 388 41.9 4.35 HVO_A0458 ParA domain protein 30.93 1 6 6 13 1.165E7 9.32 30.93 5 7 506.54 22.68 4 6 291 32.2 4.79 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 30.89 1 7 7 38 4.893E7 23.26 27.03 6 19 1710.15 30.89 7 19 259 29.9 4.36 HVO_1649 methionine adenosyltransferase 30.85 1 9 9 38 2.312E7 30.93 30.85 9 19 1596.59 30.85 9 19 402 43.5 4.45 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 96 1.681E8 108.62 30.84 8 48 5425.82 30.84 8 48 415 44.4 4.41 HVO_2758 50S ribosomal protein L11 30.82 1 4 4 25 1.087E8 26.91 23.27 3 12 1277.68 30.82 4 13 159 16.8 4.04 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 30.81 1 6 8 38 4.795E7 36.71 28.20 7 18 2207.58 30.81 8 20 383 41.9 4.21 HVO_0721 PHP domain protein 30.71 1 5 5 15 2.134E7 9.50 20.47 4 7 870.15 30.71 5 8 254 28.2 5.97 HVO_0894 acyl-CoA synthetase 30.66 1 5 13 111 1.536E8 131.53 30.66 13 56 6361.07 30.66 13 55 662 74.3 4.48 HVO_2069 RND superfamily permease 30.63 1 17 17 126 7.267E7 146.38 27.53 16 63 7598.72 30.63 17 63 839 89.4 4.42 HVO_B0375 Spo0M family protein 30.61 1 5 5 16 1.548E7 16.94 30.61 5 8 493.67 30.61 5 8 245 27.2 4.35 HVO_2122 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 30.43 1 8 8 28 6.682E7 36.40 23.37 6 13 2003.34 30.43 8 15 368 40.0 4.63 HVO_2315 "tritrans,polycis-undecaprenyl-diphosphate synthase" 30.42 1 10 10 56 1.107E7 36.51 30.42 10 28 2756.66 30.42 10 28 309 35.1 4.98 HVO_1573 DNA gyrase subunit A 30.39 1 20 20 115 7.077E7 96.43 28.19 19 54 6730.88 30.39 20 61 862 94.8 4.56 HVO_1198 UspA domain protein 30.34 1 4 4 14 2.251E7 12.97 30.34 4 7 730.74 30.34 4 7 145 15.6 4.75 HVO_2020 DUF502 family protein 30.34 1 5 5 30 6.782E7 40.52 30.34 5 15 2064.08 30.34 5 15 267 29.4 4.35 HVO_A0426 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 30.27 1 7 7 23 1.039E7 13.68 30.27 7 12 789.69 30.27 7 11 337 36.8 5.16 HVO_1079 sulfate adenylyltransferase small subunit 30.15 1 5 5 25 1.648E7 12.08 20.00 4 12 1059.95 30.15 5 13 325 37.5 4.18 HVO_0788 tryptophan synthase beta subunit 30.09 1 9 9 43 4.287E7 42.13 30.09 9 21 2685.14 30.09 9 22 422 45.7 4.65 HVO_2378 ABC-type transport system ATP-binding protein (probable substrate phosphate) 30.07 1 11 11 44 8.047E7 41.92 30.07 11 21 2616.33 30.07 11 23 296 32.6 4.44 HVO_2894 HTH-10 family transcription regulator 29.91 1 2 2 4 6.815E6 0.00 29.91 2 2 38.33 29.91 2 2 214 23.4 4.84 HVO_2740 nucleoside-diphosphate kinase 29.87 1 4 4 20 8.415E6 19.58 29.87 4 10 1352.41 29.87 4 10 154 17.5 4.50 HVO_2316 serpin family protein 29.80 1 11 11 77 9.452E7 76.14 29.80 11 39 4420.19 29.80 11 38 453 48.7 4.25 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 29.79 1 7 7 56 4.911E7 52.94 29.79 7 28 2796.13 29.79 7 28 386 40.0 4.68 HVO_0311 A-type ATP synthase subunit I 29.74 1 17 17 160 3.912E8 163.28 29.74 17 80 9827.26 28.79 16 80 733 79.5 4.41 HVO_2047 conserved hypothetical protein 29.73 1 6 6 32 1.509E7 22.52 29.73 6 16 1537.72 29.73 6 16 296 34.2 4.93 HVO_1625 conserved hypothetical protein 29.66 1 17 17 74 7.421E7 87.96 26.30 16 37 5193.95 29.66 17 37 654 70.1 4.04 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 29.64 1 11 11 48 4.850E7 49.29 29.64 11 24 2323.22 29.64 11 24 496 55.0 4.53 HVO_1164 HD family hydrolase 29.63 1 8 8 42 4.865E7 41.73 29.63 8 21 2185.40 29.63 8 21 270 29.8 4.87 HVO_A0432 conserved hypothetical protein 29.63 1 0 8 33 1.950E7 41.26 29.63 8 16 2119.70 29.63 8 17 405 44.5 5.24 HVO_1369 DUF124 family protein 29.55 1 2 2 4 1.175E7 0.00 29.55 2 2 83.17 29.55 2 2 220 23.0 4.46 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 29.52 1 9 9 52 4.037E7 69.91 29.52 9 26 3072.80 29.52 9 26 454 48.5 4.46 HVO_1370 gamma-glutamyl phosphate reductase 29.50 1 9 9 68 4.549E7 82.41 29.50 9 34 3998.43 29.50 9 34 444 48.1 4.34 HVO_1751 P-type transport ATPase (probable substrate copper/metal cation) 29.50 1 17 17 103 8.429E7 106.60 29.50 17 51 5331.19 29.50 17 52 861 89.9 4.40 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 29.46 1 6 6 42 2.655E7 55.96 24.11 5 20 2811.71 29.46 6 22 336 36.8 4.12 HVO_1894 conserved hypothetical protein 29.35 1 2 2 11 1.355E8 8.77 29.35 2 6 310.33 29.35 2 5 92 10.3 4.67 HVO_A0294 ABC-type transport system ATP-binding protein (probable substrate spermidine/putrescine) 29.12 1 9 9 81 1.947E8 84.66 29.12 9 41 4021.94 29.12 9 40 388 42.1 4.59 HVO_A0324 conserved hypothetical protein 29.02 1 3 3 10 5.868E6 2.02 29.02 3 5 316.80 29.02 3 5 193 21.0 5.06 HVO_1878 NAD synthase 28.99 1 7 7 40 6.690E7 29.90 19.93 6 19 2151.39 28.99 7 21 276 29.6 4.37 HVO_0881 signal peptide peptidase 28.83 1 7 7 38 6.305E7 43.43 28.83 7 19 2545.17 28.83 7 19 333 35.2 4.37 HVO_1481 UspA domain protein 28.83 1 3 3 15 1.452E7 19.10 28.83 3 8 776.11 28.83 3 7 163 17.7 4.40 HVO_2082 conserved hypothetical protein 28.79 1 7 7 67 3.048E8 84.25 28.79 7 34 3248.25 28.79 7 33 396 40.9 4.50 HVO_0243 threonine aldolase 28.74 1 7 7 21 9.247E6 21.21 28.74 7 11 1130.82 28.74 7 10 341 35.6 4.55 HVO_1241 SCO1/SenC/PrrC family protein 28.70 1 4 4 24 3.921E7 27.29 28.70 4 13 1490.37 28.70 4 11 223 24.6 4.45 HVO_A0331 D-galactonate dehydratase 28.65 1 6 6 21 3.037E7 24.74 28.65 6 11 1102.20 28.65 6 10 384 42.8 4.83 HVO_0469 AstE family protein 28.62 1 6 6 30 2.404E7 45.02 28.62 6 15 2306.68 28.62 6 15 318 33.9 5.85 HVO_2528 phytoene dehydrogenase (phytoene desaturase) 28.60 1 13 13 119 1.002E8 106.77 28.60 13 60 6033.68 28.60 13 59 500 55.8 4.56 HVO_0874 beta-lactamase domain protein 28.59 1 15 15 97 9.527E7 117.84 28.59 15 48 6567.68 28.59 15 49 640 71.9 5.14 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 28.57 1 5 5 40 7.630E7 40.63 28.57 5 19 1877.01 28.57 5 21 280 30.1 4.44 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 28.46 1 5 5 14 3.309E7 9.48 23.72 4 6 795.80 28.46 5 8 253 26.0 4.60 HVO_1530 dolichyl-monophosphooligosaccharide--protein glycotransferase AglB 28.46 1 19 19 92 1.655E8 104.88 24.10 16 44 5382.10 24.38 18 48 1054 113.6 4.56 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 28.43 1 25 25 143 7.979E7 160.08 28.43 25 72 7152.41 27.41 24 71 1284 141.2 4.35 HVO_0824 "probable glycosyltransferase, type 1" 28.41 1 6 6 30 4.811E7 35.56 28.41 6 15 1669.77 28.41 6 15 352 39.6 5.08 HVO_1591 conserved hypothetical protein 28.41 1 4 4 30 3.949E7 29.45 28.41 4 15 1666.45 28.41 4 15 264 28.7 5.50 HVO_1176 conserved hypothetical protein 28.29 1 7 7 34 5.335E7 18.21 27.89 6 15 1776.60 28.29 7 19 251 27.7 5.11 HVO_1268 conserved hypothetical protein 28.27 1 4 4 17 9.636E6 19.22 19.83 3 8 1017.61 28.27 4 9 237 26.4 5.21 HVO_0549 2-keto-3-deoxygluconate kinase 28.13 1 6 7 28 3.852E7 31.05 22.50 6 14 2048.57 28.13 7 14 320 34.1 4.34 HVO_1804 nicotinate phosphoribosyltransferase 28.09 1 9 9 44 7.390E7 45.06 25.00 8 21 2887.67 28.09 9 23 388 41.1 4.60 HVO_2544 30S ribosomal protein S5 28.04 1 5 5 24 1.024E8 32.77 28.04 5 12 1671.25 28.04 5 12 214 23.3 9.29 HVO_A0425 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 28.03 1 8 8 31 1.999E7 35.32 28.03 8 16 1779.21 28.03 8 15 346 38.4 5.24 HVO_2356 GNAT family acetyltransferase 28.01 1 7 7 32 2.360E7 41.16 28.01 7 16 2191.59 28.01 7 16 407 45.1 4.64 HVO_0704 "probable glycosyltransferase, type 2" 27.97 1 5 5 19 1.394E7 18.21 27.97 5 9 1070.99 27.97 5 10 261 28.4 5.30 HVO_2165 ABC-type transport system permease protein (homolog to LolDCE lipoprotein release factor) 27.97 1 9 9 45 8.997E7 28.10 23.31 7 21 1974.92 27.97 9 24 429 44.4 5.12 HVO_2558 30S ribosomal protein S3 27.96 1 6 6 37 8.702E7 47.67 23.68 5 18 3054.57 27.96 6 19 304 33.4 4.06 HVO_B0111 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 27.93 1 10 10 50 1.659E8 43.77 21.70 9 23 1975.16 27.93 10 27 401 44.2 4.54 HVO_0717 "cell division protein FtsZ, type I" 27.70 1 8 8 91 2.698E8 126.79 27.70 8 46 6838.19 27.70 8 45 379 39.8 4.40 HVO_B0382 TATA-binding transcription initiation factor 27.66 1 3 3 14 2.161E7 19.61 27.66 3 7 977.58 27.66 3 7 188 20.1 4.12 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 27.54 1 6 6 28 4.684E7 28.47 22.62 5 13 1873.22 27.54 6 15 305 33.8 4.74 HVO_B0049 precorrin-8 methylmutase 27.43 1 3 3 8 6.940E6 2.29 27.43 3 4 264.17 27.43 3 4 226 23.8 5.00 HVO_2781 DNA-directed RNA polymerase subunit D 27.41 1 5 5 18 5.221E7 12.49 27.41 5 9 780.14 27.41 5 9 259 28.1 4.32 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 27.40 1 3 3 4 5.835E6 298.71 27.40 3 4 219 22.4 4.06 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 27.39 1 7 7 32 4.125E7 29.39 27.39 7 16 1542.68 27.39 7 16 376 41.8 4.91 HVO_1034 type IV pilus biogenesis complex ATPase subunit 27.30 1 10 10 40 4.218E7 49.87 27.30 10 20 1931.04 27.30 10 20 564 64.2 4.75 HVO_1058 TrkA domain protein 27.19 1 8 8 17 1.652E7 17.11 17.30 6 8 846.50 21.80 7 9 445 47.7 4.35 HVO_2431 ABC-type transport system permease protein (probable substrate glutamine) 27.17 1 5 5 26 2.851E7 23.23 17.75 4 11 1331.64 27.17 5 15 276 29.6 5.15 HVO_0843 conserved hypothetical protein 27.13 1 3 3 7 9.822E6 3.33 20.93 2 3 282.35 27.13 3 4 129 14.7 5.57 7428712 "keratin 1, type II, cytoskeletal - human" 27.06 1 0 19 235 2.778E8 296.56 27.06 19 118 16272.37 27.06 19 117 643 65.5 6.35 HVO_0195 ribose-5-phosphate isomerase 26.96 1 4 4 9 6.089E6 8.13 14.78 3 4 364.17 26.96 4 5 230 23.2 4.54 HVO_2773 30S ribosomal protein S2 26.92 1 3 3 20 3.899E7 33.63 26.92 3 10 1490.20 26.92 3 10 260 28.3 4.16 HVO_2872 conserved hypothetical protein 26.86 1 10 10 33 2.798E7 31.80 26.86 10 17 1755.12 26.86 9 16 458 50.8 4.81 HVO_0319 A-type ATP synthase subunit D 26.81 1 6 6 25 2.742E7 27.17 26.81 6 13 1475.81 26.81 6 12 235 26.7 4.72 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 26.79 1 11 11 68 1.333E8 77.48 26.79 11 34 4505.00 26.79 11 34 586 63.4 4.70 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 26.77 1 4 4 21 5.647E7 12.87 26.77 4 10 1023.97 26.77 4 11 269 28.3 4.49 HVO_0990 DHH family phosphoesterase 26.75 1 8 9 32 1.313E7 32.67 26.75 9 16 1593.82 26.75 9 16 486 51.9 4.59 HVO_1368 probable metallo-beta-lactamase family hydrolase 26.59 1 4 4 14 1.802E7 15.73 7.49 2 6 700.88 26.59 4 8 267 29.3 4.49 HVO_2790 ATP-binding protein Mrp 26.59 1 5 5 14 1.614E7 17.79 26.59 5 7 684.66 26.59 5 7 346 36.8 4.50 HVO_2712 3'-5' RNA ligase 26.54 1 8 8 24 1.051E7 16.24 26.54 8 12 866.88 26.54 8 12 486 53.4 4.92 HVO_2016 conserved hypothetical protein 26.42 1 9 9 44 7.060E7 54.28 22.07 7 20 3284.68 26.42 9 24 299 31.2 4.70 HVO_2468 probable oxidoreductase (short-chain dehydrogenase family) 26.38 1 5 5 20 1.400E7 22.55 26.38 5 10 984.26 26.38 5 10 235 24.9 4.35 HVO_1123 thioredoxin-disulfide reductase 26.36 1 5 5 18 1.059E7 7.10 23.21 4 8 829.41 26.36 5 10 349 37.3 4.32 HVO_2435 peptidase M24 family protein 26.36 1 6 6 36 1.772E7 44.41 26.36 6 18 1925.30 26.36 6 18 368 40.0 4.53 HVO_2688 TrmB family transcription regulator 26.35 1 7 7 28 5.425E7 29.37 26.35 7 13 1882.30 26.35 7 15 353 39.3 4.58 HVO_0832 alpha/beta hydrolase fold protein 26.30 1 6 6 69 2.700E8 68.72 26.30 6 34 4621.46 26.30 6 35 308 33.3 4.67 HVO_2993 prepilin peptidase 26.29 1 6 6 25 1.222E7 31.07 26.29 6 13 1581.58 16.86 5 12 350 37.3 4.72 HVO_0467 PhoU/TrkA-C domain protein 26.12 1 8 8 42 2.176E7 45.16 26.12 8 21 2302.25 26.12 8 21 402 43.3 4.49 HVO_0639 AAA-type ATPase (MoxR subfamily) 25.95 1 6 6 23 1.979E7 27.23 20.57 5 11 1594.76 22.78 5 12 316 34.7 4.89 HVO_2080 conserved hypothetical protein 25.93 1 6 6 50 1.340E8 66.22 25.93 6 25 2343.84 25.93 6 25 540 57.0 4.30 HVO_1847 oligoendopeptidase PepF 25.88 1 10 10 43 1.958E7 38.98 20.37 9 21 2216.97 25.88 10 22 599 68.5 4.41 HVO_1710 alpha amylase 25.85 1 16 16 135 1.670E8 112.10 25.85 16 66 7551.73 25.85 16 69 677 75.0 4.45 HVO_2707 GFO family oxidoreductase 25.81 1 9 9 33 7.316E7 35.12 24.19 8 16 1930.74 25.81 9 17 372 41.0 4.55 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 25.75 1 8 8 87 3.083E8 115.42 25.75 8 46 5377.99 25.75 8 41 435 46.9 4.63 HVO_1548 conserved hypothetical protein 25.74 1 3 3 16 7.217E6 15.88 21.78 2 7 712.56 25.74 3 9 202 22.2 4.96 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 25.72 1 9 9 40 2.140E7 44.16 20.12 8 19 2004.43 25.72 9 21 661 71.0 4.35 HVO_1572 DNA gyrase subunit B 25.67 1 13 13 62 3.825E7 60.26 21.44 12 31 2910.18 25.67 13 31 639 71.2 4.83 HVO_2665 HpcH/HpaI aldolase family protein 25.66 1 6 6 15 1.390E7 12.82 21.89 5 7 735.24 25.66 6 8 265 28.3 4.50 HVO_1976 protein-export membrane protein SecD 25.57 1 8 8 98 1.537E8 158.41 25.57 8 49 7597.05 24.62 7 49 524 55.0 4.51 HVO_1094 ribonuclease P protein component 3 25.54 1 4 4 21 7.644E6 13.06 25.54 4 11 689.11 25.54 4 10 231 25.6 5.31 HVO_2057 sugar nucleotidyltransferase 25.49 1 7 7 23 3.078E7 26.21 25.49 7 11 1306.25 25.49 7 12 357 37.8 4.44 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 25.47 1 7 7 26 1.790E7 31.51 25.47 7 13 1545.48 25.47 7 13 475 49.3 4.49 HVO_1613 "probable glycosyltransferase, type 2" 25.44 1 4 4 40 1.189E8 37.46 25.44 4 20 2067.72 25.44 4 20 228 25.1 4.79 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 25.41 1 8 8 28 9.392E7 29.59 18.92 6 13 1780.42 25.41 8 15 370 41.9 4.48 HVO_0109 cysteine desulfurase 25.35 1 8 8 36 1.877E7 37.77 25.35 8 17 1774.69 25.35 8 19 426 46.8 4.56 HVO_A0302 asparaginase/glutaminase family protein 25.31 1 5 5 24 2.191E8 31.33 25.31 5 13 1451.33 25.31 5 11 324 33.4 4.69 HVO_0480 phosphoglycerate kinase 25.19 1 8 8 38 1.764E7 46.37 25.19 8 19 2461.04 25.19 8 19 401 43.6 4.37 HVO_1637 FKBP-type peptidylprolyl isomerase 25.16 1 5 5 21 7.605E7 24.57 16.67 4 10 1141.20 25.16 5 11 306 33.8 3.76 >sp|TRYP_PIG| 25.11 1 5 5 497 8.670E9 692.07 25.11 5 248 32257.62 25.11 5 249 231 24.4 7.18 HVO_1541 glycerol kinase 25.10 1 8 8 36 6.171E7 37.86 21.76 7 17 2459.72 25.10 8 19 510 56.7 4.50 HVO_0203 replication factor C small subunit 25.08 1 7 7 37 1.741E7 53.64 25.08 7 18 2192.23 25.08 7 19 327 36.2 4.51 HVO_0541 aconitate hydratase 25.05 1 16 16 79 4.785E7 84.05 25.05 16 39 4600.31 25.05 16 40 938 102.1 4.40 HVO_0401 UspA domain protein 25.00 1 3 3 13 1.819E7 17.51 25.00 3 6 1090.91 25.00 3 7 152 16.4 4.79 HVO_A0305 methylmalonate-semialdehyde dehydrogenase 24.95 1 9 9 47 1.599E8 50.13 24.95 9 24 2603.26 24.95 9 23 489 52.1 4.59 HVO_1660 DisA-N domain protein 24.91 1 5 5 18 2.531E7 17.14 24.91 5 9 1231.18 24.91 5 9 269 28.9 4.73 HVO_2083 ABC-type transport system ATP-binding protein (probable substrate macrolides) 24.89 1 5 5 12 1.104E7 10.24 20.44 4 5 875.17 24.89 5 7 225 24.9 4.54 HVO_1031 thioredoxin-disulfide reductase 24.85 1 5 5 22 1.544E7 16.33 24.85 5 11 823.90 24.85 5 11 342 37.4 4.46 HVO_0350 DNA-directed RNA polymerase subunit A'' 24.82 1 10 10 60 6.595E7 67.15 24.82 10 30 2938.86 24.82 10 30 419 46.1 4.35 HVO_B0371 aldehyde dehydrogenase 24.80 1 5 5 36 3.111E7 54.26 24.80 5 18 2409.84 24.80 5 18 496 52.5 4.39 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 24.77 1 6 6 20 1.375E7 22.34 24.77 6 10 1301.38 24.77 6 10 323 34.9 5.24 HVO_0891 ABC-type transport system ATP-binding protein (probable substrate copper) 24.73 1 5 5 20 1.181E7 16.91 24.73 5 10 1044.46 24.73 5 10 283 28.6 4.35 HVO_1727 TATA-binding transcription initiation factor 24.73 1 4 4 28 7.218E7 31.94 24.73 4 14 1973.16 24.73 4 14 186 19.9 4.36 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 24.71 1 0 3 19 7.627E7 7.65 24.71 3 10 723.51 24.71 3 9 85 10.0 5.94 HVO_1932 2-D-hydroxyacid dehydrogenase 24.68 1 6 6 24 1.431E7 27.86 24.68 6 12 1257.87 24.68 6 12 308 33.0 4.60 HVO_1979 tRNA pseudouridine synthase Pus10 24.59 1 7 7 39 3.212E7 43.45 18.74 6 19 2161.03 24.59 7 20 427 46.9 4.39 HVO_1048 phosphoribosylformylglycinamidine synthase 2 24.50 1 11 11 44 2.772E7 44.48 23.50 9 19 2576.78 24.50 11 25 702 72.9 4.18 HVO_1496 phosphotransferase system component I 24.42 1 11 11 50 4.130E7 59.53 23.01 10 24 2887.14 24.42 11 26 565 60.3 4.21 HVO_0573 endonuclease IV 24.40 1 4 4 20 1.232E7 19.32 24.40 4 10 1143.39 24.40 4 10 291 31.4 4.44 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 24.40 1 4 4 23 2.626E7 22.10 24.40 4 11 1270.02 24.40 4 12 336 36.0 4.51 HVO_A0494 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 24.38 1 6 6 56 4.201E7 43.16 24.38 6 27 2782.48 24.38 6 29 443 47.8 4.21 HVO_2300 translation initiation factor aIF-5A 24.19 1 2 2 8 1.364E7 6.73 24.19 2 4 383.50 24.19 2 4 124 14.2 5.22 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 24.14 1 7 7 17 7.005E6 13.89 24.14 7 9 826.92 18.97 6 8 406 43.1 4.60 HVO_1854 histidine--tRNA ligase 24.13 1 8 8 41 3.810E7 61.77 24.13 8 21 2749.93 21.81 7 20 431 47.1 4.37 HVO_B0292 ABC-type transport system periplasmic substrate-binding protein (probable substrate glycerol-3-phosphate) 24.13 1 8 8 52 8.505E7 69.82 24.13 8 26 2671.88 24.13 8 26 489 52.6 4.36 HVO_1240 conserved hypothetical protein 24.08 1 6 6 42 3.159E7 39.85 24.08 6 21 1867.30 24.08 6 21 353 37.4 4.49 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 24.08 1 8 8 40 3.903E7 34.54 22.34 7 20 2018.29 22.13 7 20 461 50.7 4.73 HVO_2846 SpoVR family protein 24.07 1 14 14 49 2.416E7 39.77 22.87 13 24 2250.74 24.07 14 25 669 78.0 4.82 HVO_1523 agl cluster protein AglQ 23.99 1 4 4 24 8.805E6 18.28 23.99 4 12 1038.67 23.99 4 12 371 42.1 6.04 HVO_0561 50S ribosomal protein L15e 23.98 1 5 6 48 3.852E8 47.94 23.98 6 24 2436.80 23.98 6 24 196 22.5 11.15 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 23.96 1 10 10 34 2.109E7 21.24 23.96 10 18 1573.57 23.96 10 16 626 67.6 4.65 HVO_2943 dihydroorotate dehydrogenase (quinone) 23.93 1 5 5 22 2.014E7 27.01 23.93 5 11 1384.51 23.93 5 11 351 37.4 4.72 HVO_0096 arNOG08307 family NADH-binding domain protein 23.87 1 6 6 19 2.078E7 22.14 20.65 5 10 933.27 23.87 6 9 310 33.3 5.05 HVO_0447 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate/phosphonate) 23.85 1 4 4 106 2.455E8 62.45 23.85 4 54 2394.19 23.85 4 52 348 36.5 3.75 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 23.85 1 7 7 33 3.499E7 37.34 23.85 7 16 1719.77 23.85 7 17 348 38.2 4.32 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 23.78 1 8 8 33 3.886E7 36.18 21.14 7 16 2110.82 23.78 8 17 492 52.1 4.83 HVO_0148 urease alpha subunit 23.77 1 7 7 122 7.076E7 116.13 23.77 7 61 5937.42 23.77 7 61 568 60.3 4.54 HVO_2770 conserved hypothetical protein 23.75 1 7 7 27 7.807E7 19.77 23.75 7 13 1736.67 23.75 7 14 320 35.7 5.15 HVO_1125 cysteine--tRNA ligase 23.68 1 8 8 55 2.531E7 57.39 23.68 8 26 3090.24 23.68 8 29 494 55.2 4.56 HVO_1888 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfate/tungstate) 23.68 1 7 7 87 4.291E8 110.74 23.68 7 45 5194.34 23.68 7 42 342 35.9 4.34 HVO_0285 probable metalloprotease 23.59 1 7 7 31 3.159E7 38.82 23.59 7 16 2183.87 16.41 6 15 390 42.1 4.98 HVO_2059 NAD-dependent epimerase/dehydratase 23.55 1 6 6 24 3.853E7 16.38 20.97 5 12 1058.48 23.55 6 12 310 34.1 4.40 HVO_C0054 hypothetical protein 23.55 1 6 6 36 3.728E7 44.09 23.55 6 18 2391.71 22.09 5 18 344 37.5 4.70 HVO_0175 DNA polymerase sliding clamp 23.48 1 4 4 16 4.918E7 20.37 23.48 4 8 1111.78 23.48 4 8 247 26.7 4.39 HVO_2302 ubiquinone biosynthesis protein UbiB 23.48 1 9 10 64 2.941E7 68.23 22.04 9 31 3984.25 23.48 10 33 558 63.0 4.69 HVO_A0477 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 23.48 1 6 6 57 4.052E7 86.88 23.48 6 28 4553.49 23.48 6 29 396 42.3 4.28 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 23.38 1 18 18 115 8.543E7 155.56 23.38 18 57 7451.57 23.38 18 58 1082 117.2 4.32 HVO_2912 ThiJ/PfpI domain protein 23.38 1 2 2 4 1.008E7 6.05 23.38 2 2 210.41 23.38 2 2 201 20.9 4.36 HVO_0953 conserved hypothetical protein 23.37 1 13 13 54 2.484E7 50.24 23.37 13 27 2753.50 18.79 12 27 612 65.9 4.64 HVO_B0149 oleate hydratase 23.26 1 7 8 25 1.076E8 16.13 23.26 8 12 929.65 23.26 8 13 533 60.1 4.64 HVO_B0153 CapB domain protein 23.26 1 9 9 47 2.922E7 48.62 23.26 9 23 2680.48 23.26 9 24 546 60.7 4.87 HVO_A0491 ABC-type transport system ATP-binding protein (probable substrate sugar) 23.24 1 5 6 28 1.821E7 29.08 22.19 5 14 1249.25 23.24 6 14 383 41.1 4.48 HVO_B0154 receiver/sensor box histidine kinase 23.14 1 21 22 86 3.697E7 84.91 23.14 22 44 4375.00 22.67 21 42 1301 144.1 4.39 HVO_B0058 precorrin-3B C17-methyltransferase 23.13 1 4 4 20 2.890E7 22.93 23.13 4 10 1268.29 23.13 4 10 294 31.8 4.40 HVO_2267 hypothetical protein 23.12 1 8 8 44 3.102E7 27.05 23.12 8 22 2120.89 23.12 8 22 385 44.3 4.56 HVO_0789 tryptophan synthase alpha subunit 23.10 1 3 3 14 6.901E6 19.64 23.10 3 7 725.49 23.10 3 7 277 29.6 4.21 HVO_1685 conserved hypothetical protein 22.97 1 10 10 45 5.543E7 35.71 22.97 10 22 2271.36 22.97 10 23 492 54.5 5.74 HVO_0145 replication factor C small subunit 22.87 1 7 7 19 7.529E6 16.58 22.87 7 10 935.53 19.65 6 9 341 37.8 4.93 HVO_0940 P-type transport ATPase (probable substrate copper/metal cation) 22.83 1 11 11 42 1.250E7 55.68 22.83 11 21 2713.26 22.83 11 21 828 85.9 4.53 HVO_1916 Kef-type transport system (probable substrate potassium) 22.83 1 11 11 92 1.041E8 100.73 22.83 11 46 5147.74 22.83 11 46 635 66.2 4.63 HVO_0116 50S ribosomal protein L31e 22.83 1 2 2 2 5.730E6 98.93 22.83 2 2 92 10.5 5.49 HVO_1831 ferredoxin (2Fe-2S) 22.80 1 4 4 49 1.481E8 55.28 22.80 4 24 2790.82 22.80 4 25 193 20.4 3.98 HVO_0892 ABC-type transport system periplasmic substrate-binding protein (probable substrate copper) 22.78 1 12 12 66 3.979E7 66.34 22.78 12 33 3616.38 22.78 12 33 641 67.1 4.70 HVO_2081 pectin lyase domain protein 22.77 1 17 17 129 3.994E7 176.19 22.77 17 64 9213.87 22.77 17 65 1041 109.7 5.34 HVO_1459 ThuA family protein 22.69 1 3 3 18 1.496E7 21.00 22.69 3 9 899.12 22.69 3 9 238 26.8 4.67 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 22.66 1 10 11 53 4.390E7 58.17 22.10 10 26 2901.79 22.66 11 27 706 73.3 4.39 HVO_B0117 conserved hypothetical protein 22.60 1 4 4 18 8.978E7 22.67 22.60 4 9 1178.77 22.60 4 9 208 23.3 4.58 HVO_0212 homolog to lactoylglutathione lyase 22.58 1 2 2 8 3.184E7 9.35 22.58 2 4 453.74 22.58 2 4 124 13.5 4.13 HVO_0360 30S ribosomal protein S10 22.55 1 2 2 6 1.233E7 7.85 22.55 2 3 399.69 22.55 2 3 102 11.5 4.88 HVO_1228 halocyanin 22.53 1 13 13 161 2.190E8 185.91 22.53 13 80 8831.79 20.46 12 81 821 83.7 4.17 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 22.48 1 7 7 42 3.549E7 44.28 22.48 7 22 2540.95 22.48 7 20 427 45.4 4.56 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 22.46 1 2 12 47 7.992E7 32.22 22.46 12 24 1866.37 22.46 12 23 472 51.6 5.16 HVO_0841 cytochrome bc1 complex cytochrome b/c subunit 22.44 1 5 5 42 2.653E8 48.56 22.44 5 21 2198.54 20.08 4 21 254 28.8 5.72 HVO_1917 acyl-CoA synthetase 22.37 1 11 11 31 2.460E7 28.18 21.02 10 14 1406.16 22.37 11 17 666 74.0 4.78 HVO_1988 conserved hypothetical protein 22.35 1 4 4 76 2.373E8 136.35 22.35 4 38 5853.98 22.35 4 38 349 35.2 4.25 HVO_0048 argininosuccinate lyase 22.34 1 8 8 51 3.197E7 58.56 19.88 7 19 4273.41 22.34 8 32 488 50.8 4.53 HVO_0153 urease accessory protein UreF 22.27 1 3 3 8 5.310E6 8.05 17.47 2 3 233.23 22.27 3 5 229 24.7 4.92 HVO_A0306 4-aminobutyrate aminotransferase 22.25 1 10 10 79 1.957E8 87.03 21.57 9 38 5345.83 22.25 10 41 445 47.6 4.68 HVO_1354 DNA mismatch repair protein MutS 22.24 1 11 11 38 1.415E7 35.32 22.24 11 19 1883.45 22.24 11 19 580 62.1 4.56 HVO_1191 proline dehydrogenase 22.22 1 4 4 20 8.217E7 24.78 22.22 4 10 1308.99 22.22 4 10 279 31.0 5.02 HVO_0792 3-dehydroquinate synthase type II 22.19 1 7 7 32 1.959E7 38.66 22.19 7 16 1683.66 22.19 7 16 392 43.1 4.44 HVO_1008 GFO family oxidoreductase 21.99 1 5 5 15 2.210E7 18.38 21.99 5 8 1014.39 15.36 4 7 332 36.0 4.72 HVO_C0042 helicase domain protein 21.98 1 22 22 97 7.138E7 112.81 21.43 21 48 5312.54 21.98 22 49 1274 144.4 4.67 HVO_2607 PQQ repeat protein 21.92 1 8 8 45 4.557E7 45.82 21.92 8 22 2354.54 21.92 8 23 406 42.3 4.86 HVO_0787 indole-3-glycerol-phosphate synthase 21.91 1 3 3 8 7.814E6 5.76 21.91 3 4 395.65 21.91 3 4 251 26.7 4.44 HVO_1658 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 21.67 1 3 3 10 6.275E6 1.82 21.67 3 5 345.00 21.67 3 5 180 19.6 5.24 HVO_2695 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 21.29 1 6 6 73 1.047E8 80.58 21.29 6 37 4459.99 21.29 6 36 512 55.4 4.42 HVO_0049 argininosuccinate synthase 21.23 1 9 9 38 9.628E7 27.33 21.23 9 19 1689.88 21.23 9 19 405 44.5 4.34 HVO_0424 ABC-type transport system ATP-binding protein 21.19 1 9 9 27 1.019E7 25.25 21.19 9 14 1044.08 18.21 8 13 604 67.2 4.49 HVO_0388 homolog to ribonuclease R 21.18 1 9 9 36 1.379E7 31.95 21.18 9 18 1735.36 21.18 9 18 439 50.3 4.73 HVO_A0601 NosL family protein 21.18 1 2 2 6 8.489E6 0.00 21.18 2 3 68.78 21.18 2 3 203 21.5 4.60 HVO_0357 ACT domain protein 21.16 1 4 4 16 2.688E7 13.46 21.16 4 8 757.21 21.16 4 8 189 20.2 4.59 HVO_0353 30S ribosomal protein S12 21.13 1 3 3 10 1.109E7 10.72 21.13 3 5 518.84 21.13 3 5 142 15.5 9.91 HVO_0324 arginine--tRNA ligase 21.12 1 10 10 36 2.876E7 35.40 19.42 9 18 1778.38 18.57 9 18 587 65.0 4.35 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 21.05 1 3 3 10 2.477E7 10.50 21.05 3 5 524.22 21.05 3 5 190 20.6 4.30 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 21.03 1 4 4 32 3.915E7 43.18 21.03 4 16 2112.89 21.03 4 16 252 26.0 4.39 HVO_0951 hypothetical protein 21.02 1 6 6 63 6.135E7 65.99 21.02 6 31 3759.59 21.02 6 32 333 38.1 4.69 HVO_A0339 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 21.01 1 8 8 28 3.644E7 31.04 17.59 7 13 1473.59 21.01 8 15 557 61.2 4.39 HVO_1291 fumarylacetoacetase family protein 20.99 1 3 3 16 4.904E7 11.88 20.99 3 8 632.27 20.99 3 8 243 26.3 4.55 HVO_2800 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 20.95 1 4 4 21 5.742E7 21.93 14.23 3 8 1730.25 20.95 4 13 253 27.6 4.42 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 20.94 1 3 3 18 1.167E7 20.71 10.83 2 7 1085.16 20.94 3 11 277 30.6 4.30 HVO_2156 UspA domain protein 20.93 1 5 5 17 1.720E7 20.34 17.94 4 8 1097.11 20.93 5 9 301 31.6 4.69 HVO_0445 ABC-type transport system permease protein (probable substrate phosphate/phosphonate) 20.87 1 4 4 27 2.870E7 24.06 20.87 4 13 1039.66 20.87 4 14 321 35.5 4.81 HVO_2798 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 20.82 1 5 5 748 2.885E9 905.06 13.73 4 370 36991.80 20.82 5 378 437 44.6 3.95 HVO_2169 conserved hypothetical protein 20.81 1 5 5 23 3.634E7 19.89 20.81 5 11 1134.20 20.81 5 12 346 36.5 4.39 HVO_1778 catalase-peroxidase 20.75 1 13 13 146 2.120E8 103.99 20.75 13 72 6217.45 20.75 13 74 718 80.0 4.31 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 20.72 1 3 11 40 7.973E7 22.98 16.28 10 20 1660.88 20.72 11 20 473 51.2 5.05 HVO_0417 metal-dependent carboxypeptidase 20.72 1 8 8 36 5.133E8 35.27 17.33 7 17 2369.15 20.72 8 19 502 57.3 4.42 HVO_1540 glycerol-3-phosphate dehydrogenase subunit C 20.64 1 8 8 66 1.405E8 76.83 20.64 8 33 4456.00 20.64 8 33 436 48.6 4.61 HVO_0046 putative glutamate--argW ligase 20.62 1 5 5 15 1.497E7 13.09 15.81 4 7 765.88 20.62 5 8 291 31.9 4.87 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 20.62 1 2 2 4 6.309E6 4.45 20.62 2 2 175.33 20.62 2 2 97 10.8 4.53 HVO_2061 "probable glycosyltransferase, type 2" 20.58 1 5 5 42 1.133E8 41.81 20.58 5 21 2199.61 20.58 5 21 413 43.8 4.50 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 20.58 1 5 5 30 4.760E7 33.50 20.58 5 15 1734.07 20.58 5 15 413 45.8 4.45 HVO_0014 ATP-dependent DNA helicase Hel308a 20.56 1 12 12 50 9.219E6 58.82 19.35 11 24 2766.45 20.56 12 26 827 90.3 4.67 HVO_B0115 fumarylacetoacetase family protein 20.49 1 5 5 19 3.624E7 22.86 20.49 5 10 1019.46 20.49 5 9 283 30.3 4.21 HVO_1546 dihydroxyacetone kinase subunit DhaK 20.48 1 9 9 69 5.579E7 74.57 20.48 9 34 3646.64 20.48 9 35 332 34.8 4.22 HVO_A0547 DUF1028 family protein 20.42 1 4 4 7 1.417E7 7.27 20.42 4 4 296.50 16.22 3 3 333 35.2 4.16 HVO_1261 conserved hypothetical protein 20.40 1 9 9 26 2.622E7 26.43 20.40 9 13 1551.60 20.40 9 13 598 62.6 4.64 HVO_2551 50S ribosomal protein L5 20.35 1 3 3 20 3.403E7 32.26 20.35 3 10 1776.00 20.35 3 10 172 19.1 4.78 HVO_1437 conserved hypothetical protein 20.20 1 4 4 13 7.000E6 11.37 20.20 4 7 571.14 20.20 4 6 203 22.3 4.94 HVO_0959 conserved hypothetical protein 20.18 1 3 3 15 7.285E6 16.79 20.18 3 7 958.13 20.18 3 8 228 25.7 4.84 HVO_2024 conserved hypothetical protein 20.10 1 4 4 20 1.568E7 28.08 20.10 4 10 1290.89 20.10 4 10 408 41.8 4.26 HVO_1300 triosephosphate isomerase 20.09 1 4 4 18 7.234E7 17.66 20.09 4 9 932.56 20.09 4 9 214 21.3 4.26 HVO_1504 3-isopropylmalate dehydratase large subunit 20.08 1 7 7 28 2.516E7 31.33 20.08 7 14 1785.62 20.08 7 14 473 51.6 4.55 HVO_0331 proline dehydrogenase 20.07 1 4 4 16 5.145E6 12.33 20.07 4 8 644.95 20.07 4 8 279 30.9 4.68 HVO_2297 deoxyhypusine synthase 20.06 1 4 4 14 5.451E6 16.92 20.06 4 7 690.32 20.06 4 7 359 38.6 4.59 HVO_2495 DUF106 family protein 20.00 1 8 8 58 1.727E8 56.64 20.00 8 30 3235.96 20.00 8 28 305 33.5 4.58 HVO_2546 50S ribosomal protein L19e 19.87 1 3 3 12 3.684E7 10.36 19.87 3 6 767.60 19.87 3 6 151 17.3 9.98 HVO_2630 conserved hypothetical protein 19.87 1 5 5 22 8.983E6 18.92 19.87 5 11 1485.48 19.87 5 11 302 32.9 4.48 HVO_2617 TrkA-C domain protein 19.85 1 7 7 35 4.105E7 43.87 19.85 7 18 1688.24 17.12 6 17 403 42.0 4.96 HVO_2397 ABC-type transport system periplasmic substrate-binding protein (probable substrate zinc) 19.84 1 4 4 20 1.886E7 13.44 19.84 4 10 1094.82 19.84 4 10 368 40.1 4.53 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 19.82 1 5 5 12 2.008E7 9.28 19.82 5 6 683.47 19.82 5 6 333 36.7 4.56 HVO_A0328 2-keto-3-deoxygluconate kinase 19.81 1 4 5 18 1.738E7 18.81 19.81 5 9 1048.05 19.81 5 9 318 34.0 4.60 HVO_0724 ArsA family ATPase 19.80 1 6 6 29 2.908E7 20.36 19.80 6 14 1300.43 19.80 6 15 409 43.9 4.22 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 19.75 1 5 5 32 5.606E7 35.42 16.20 4 15 1600.88 19.75 5 17 395 42.4 4.54 HVO_2690 GFO family oxidoreductase 19.67 1 6 6 29 8.246E7 18.97 19.67 6 15 1359.66 19.67 6 14 366 40.0 4.60 HVO_0697 PAC2 family protein 19.61 1 3 3 10 7.917E6 16.40 19.61 3 5 669.60 19.61 3 5 255 27.4 4.08 HVO_0982 NADH dehydrogenase-like complex subunit I 19.61 1 2 2 8 3.739E7 10.24 19.61 2 4 528.32 19.61 2 4 153 17.7 4.88 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 19.61 1 7 7 56 1.720E8 49.17 19.61 7 27 2672.20 19.61 7 29 357 40.3 4.40 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 19.54 1 4 4 14 1.104E7 6.47 19.54 4 7 391.69 19.54 4 7 348 36.7 4.69 HVO_0250 DUF21/CBS domain protein 19.53 1 7 7 57 6.689E7 74.83 19.53 7 28 4047.17 19.53 7 29 471 51.7 4.28 HVO_0002 signal peptidase I 19.51 1 3 3 16 3.166E7 18.19 19.51 3 8 846.32 19.51 3 8 287 30.3 4.60 HVO_2706 translation initiation factor aIF-2B delta subunit 19.50 1 2 2 6 9.780E6 5.76 19.50 2 3 328.40 19.50 2 3 282 30.7 4.42 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 19.50 1 7 7 57 1.015E8 43.76 17.75 6 28 2889.73 19.50 7 29 400 44.2 4.32 HVO_2648 phosphoglycerate dehydrogenase 19.44 1 4 4 18 3.457E7 20.01 19.44 4 9 1224.85 19.44 4 9 319 34.2 4.64 HVO_2456 anthranilate phosphoribosyltransferase 19.34 1 3 3 14 1.028E7 20.22 19.34 3 7 1113.94 19.34 3 7 331 33.8 4.35 HVO_2286 conserved hypothetical protein 19.32 1 6 6 20 1.472E7 20.84 19.32 6 10 1113.76 19.32 6 10 559 62.3 4.35 HVO_B0319 IclR family transcription regulator 19.32 1 4 4 10 1.406E7 10.91 7.95 2 4 587.97 19.32 4 6 264 29.3 5.14 HVO_1478 transcription initiation factor TFB 19.24 1 4 6 49 4.386E7 45.76 19.24 6 24 2972.72 19.24 6 25 317 35.7 5.47 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 19.18 1 5 5 14 5.260E6 4.64 19.18 5 7 440.67 15.09 4 7 464 53.1 4.54 HVO_1529 glycosyltransferase AglG 19.17 1 7 7 41 8.303E7 37.78 19.17 7 20 2288.43 19.17 7 21 313 35.8 4.59 HVO_0477 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 19.12 1 2 2 2 3.673E6 54.56 19.12 2 2 319 33.4 4.18 HVO_1911 nitrite reductase (ferredoxin) (nonfunctional) 19.04 1 8 8 35 2.499E7 32.23 19.04 8 18 1473.05 16.81 7 17 583 65.1 4.70 HVO_2981 uracil phosphoribosyltransferase 19.03 1 3 3 8 1.903E7 7.35 11.50 2 3 567.11 19.03 3 5 226 24.5 4.49 HVO_1500 1-phosphofructokinase 19.02 1 3 3 8 1.937E6 4.78 19.02 3 4 321.43 9.51 2 4 305 32.0 4.51 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 19.01 1 0 7 27 7.167E7 25.34 15.89 6 14 1598.89 16.67 6 13 384 42.4 5.40 HVO_0944 ba3-type terminal oxidase subunit II 18.99 1 3 3 26 7.435E7 26.97 18.99 3 13 1458.77 18.99 3 13 179 19.4 4.28 HVO_1289 OsmC domain protein 18.94 1 2 2 6 5.241E7 5.86 18.94 2 3 261.84 18.94 2 3 132 14.2 3.85 HVO_0958 conserved hypothetical protein 18.92 1 2 2 10 1.645E7 11.36 18.92 2 5 490.02 18.92 2 5 148 15.5 10.26 HVO_B0057 precorrin-3B C17-methyltransferase 18.90 1 3 3 18 2.901E7 15.66 18.90 3 9 862.24 18.90 3 9 344 36.3 4.31 HVO_0008 aspartate kinase 18.88 1 5 5 41 9.048E7 48.24 18.88 5 20 2297.96 18.88 5 21 392 41.7 4.46 HVO_0954 conserved hypothetical protein 18.83 1 3 3 9 8.788E6 6.35 12.99 2 4 516.90 18.83 3 5 154 16.4 10.08 HVO_2618 TrkA-C domain protein 18.76 1 8 8 43 3.899E7 41.05 18.76 8 21 2146.86 18.76 8 22 501 50.6 4.49 HVO_0685 DUF3100 family protein 18.71 1 5 5 28 3.366E7 37.07 18.71 5 14 1622.14 18.71 5 14 294 30.1 5.29 HVO_1287 PfpI family protease 18.69 1 2 2 10 1.066E7 9.04 18.69 2 5 552.15 18.69 2 5 198 21.5 4.53 HVO_1140 acyl-CoA dehydrogenase 18.68 1 5 5 26 1.747E7 33.53 18.68 5 13 1568.10 18.68 5 13 380 41.2 4.55 HVO_A0303 probable allantoinase 18.52 1 5 5 52 1.501E8 61.93 18.52 5 26 3341.28 18.52 5 26 459 50.1 4.42 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 18.51 1 4 4 26 1.274E7 38.94 15.47 3 12 1953.57 18.51 4 14 362 39.6 4.82 HVO_1901 translation initiation factor aIF-2 gamma subunit 18.49 1 7 7 39 5.246E7 46.23 18.49 7 19 2158.34 18.49 7 20 411 43.9 4.36 HVO_A0439 DUF2800 family protein 18.40 1 3 3 7 1.586E6 2.62 18.40 3 3 193.60 18.40 3 4 326 36.9 4.51 HVO_0756 phosphoesterase RecJ domain protein 18.27 1 4 4 15 1.025E7 17.98 18.27 4 8 1026.04 10.66 3 7 394 41.5 4.78 HVO_0602 3-dehydroquinate dehydratase 18.22 1 4 4 14 1.172E7 14.74 18.22 4 7 675.50 18.22 4 7 247 27.3 4.51 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 18.16 1 5 5 30 6.366E7 27.88 18.16 5 15 1582.05 18.16 5 15 347 36.8 4.93 HVO_2945 valine--tRNA ligase 18.16 1 10 10 30 2.989E7 23.96 16.67 9 16 1617.97 14.48 9 14 870 98.9 4.36 HVO_1137 ion channel pore / TrkA domain protein 18.12 1 7 7 26 1.905E7 31.05 18.12 7 13 1455.76 18.12 7 13 552 58.7 4.56 HVO_2418 conserved hypothetical protein 18.05 1 9 9 38 2.782E7 46.40 15.58 8 19 2160.26 18.05 9 19 892 94.6 4.16 HVO_0583 conserved hypothetical protein 18.04 1 3 3 10 5.128E6 12.74 18.04 3 5 614.47 18.04 3 5 194 21.2 4.42 HVO_0681 DNA topoisomerase I 17.98 1 13 13 30 1.529E7 28.50 14.88 11 14 1454.32 17.98 13 16 840 93.6 4.58 HVO_1576 NAD-dependent epimerase/dehydratase 17.97 1 1 5 22 1.373E7 17.03 17.97 5 11 1179.09 17.97 5 11 306 33.9 4.51 HVO_0530 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 17.94 1 4 4 26 7.650E7 30.82 17.94 4 13 1047.30 17.94 4 13 457 48.1 4.11 HVO_A0323 ABC-type transport system ATP-binding protein 17.93 1 3 3 10 9.637E6 5.32 17.93 3 5 409.09 17.93 3 5 251 27.2 4.86 HVO_0054 glycine--tRNA ligase 17.85 1 7 7 38 1.003E8 49.22 15.49 6 18 2591.60 17.85 7 20 594 64.9 4.21 HVO_0687 M20 family amidohydrolase 17.79 1 6 6 18 1.745E7 24.61 17.79 6 9 1145.97 17.79 6 9 444 47.5 4.58 HVO_B0059 cobalt-precorrin 5A hydrolase 17.79 1 4 4 15 1.592E7 17.99 17.79 4 8 638.03 17.79 4 7 326 34.5 4.51 HVO_1407 HTH domain protein 17.78 1 3 3 14 8.546E6 10.59 17.78 3 7 798.50 17.78 3 7 225 24.9 4.45 HVO_1629 conserved hypothetical protein 17.70 1 7 7 22 4.948E7 13.53 15.07 6 9 1215.78 17.70 7 13 531 56.3 4.69 HVO_A0624 P-type transport ATPase (probable substrate zinc/cadmium) 17.65 1 11 11 94 4.306E7 102.09 17.65 11 47 4968.13 17.65 11 47 895 92.5 4.42 HVO_C0075 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 17.56 1 8 8 50 3.721E7 61.97 17.56 8 25 2509.31 17.56 8 25 558 61.3 4.56 HVO_1513 conserved hypothetical protein 17.54 1 3 3 13 4.559E7 20.48 17.54 3 7 835.06 14.04 2 6 228 25.1 5.07 HVO_2721 amidophosphoribosyltransferase 17.44 1 6 6 22 2.345E7 23.78 17.44 6 11 1201.43 17.44 6 11 493 53.4 4.78 HVO_2427 replication factor C large subunit 17.42 1 7 7 37 2.662E7 39.24 17.42 7 18 2002.11 17.42 7 19 488 53.4 4.67 21961227 Keratin 6B [Homo sapiens] 17.38 1 0 9 53 1.023E8 57.20 15.25 8 26 3143.08 17.38 9 27 564 60.0 8.00 HVO_A0283 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 17.33 1 5 5 14 1.876E7 11.74 10.22 4 7 761.14 15.56 4 7 450 49.1 4.51 HVO_1944 conserved hypothetical protein 17.31 1 4 4 11 1.841E7 12.69 9.38 3 5 626.91 17.31 4 6 416 43.0 4.22 HVO_1558 cytochrome P450 17.28 1 7 7 28 1.618E7 22.10 17.28 7 14 1225.77 17.28 7 14 434 48.4 4.92 HVO_A0627 conserved hypothetical protein 17.23 1 4 4 20 2.962E7 17.43 17.23 4 10 1114.60 17.23 4 10 354 38.1 4.70 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 17.20 1 0 9 33 9.003E7 28.41 15.07 8 17 1875.33 15.60 8 16 564 60.0 8.00 HVO_2454 anthranilate synthase component I 17.18 1 7 7 15 7.172E6 17.79 17.18 7 8 560.74 15.84 6 7 524 55.9 4.56 HVO_1675 magnesium transport protein CorA 17.13 1 5 5 16 1.624E7 12.36 12.23 4 7 862.94 17.13 5 9 327 37.2 4.55 HVO_1387 enoyl-CoA hydratase 17.12 1 4 4 21 2.350E7 18.66 17.12 4 11 935.36 17.12 4 10 257 27.5 4.51 HVO_0306 conserved hypothetical protein 17.09 1 5 5 30 1.484E7 36.38 17.09 5 15 1621.73 17.09 5 15 392 42.1 4.30 HVO_1340 "probable glycosyltransferase, type 1" 17.07 1 5 5 28 2.322E7 32.65 17.07 5 14 1828.84 17.07 5 14 375 41.0 4.42 HVO_B0061 precorrin-2 C20-methyltransferase 17.02 1 3 3 8 1.688E7 10.28 17.02 3 4 359.23 17.02 3 4 235 25.3 4.63 HVO_1260 von Willebrand factor type A domain protein 16.99 1 12 12 44 1.858E7 52.07 16.99 12 22 2521.01 15.28 11 22 818 85.1 4.65 HVO_1547 isoleucine--tRNA ligase 16.97 1 13 13 78 8.445E7 76.11 16.97 13 38 3764.24 16.97 13 40 1043 117.9 4.30 HVO_2541 protein translocase subunit SecY 16.97 1 7 7 43 6.288E7 31.62 16.97 7 22 1958.47 16.97 7 21 489 52.3 6.81 HVO_2209 probable branched-chain amino acid dehydrogenase E1 component alpha subunit 16.95 1 4 4 13 1.639E7 13.46 16.95 4 7 691.24 16.95 4 6 348 38.7 4.70 HVO_1609 conserved hypothetical protein 16.90 1 4 4 18 4.683E7 20.11 16.90 4 9 1587.97 16.90 4 9 290 31.0 4.58 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 16.78 1 4 4 18 1.536E7 17.52 16.78 4 9 1006.33 16.78 4 9 286 31.2 4.54 HVO_0972 DUF1628 family protein 16.76 1 2 2 52 7.293E7 83.53 16.76 2 26 4170.59 16.76 2 26 173 17.7 4.09 HVO_A0551 acyl-CoA synthetase 16.73 1 8 8 28 3.398E7 30.97 16.73 8 14 1379.86 16.73 8 14 538 59.6 4.65 HVO_0151 urease accessory protein UreD 16.72 1 3 3 8 1.005E7 10.36 16.72 3 4 422.33 16.72 3 4 299 31.3 4.98 HVO_0358 homoserine dehydrogenase 16.72 1 4 4 24 8.947E7 21.20 16.72 4 11 1356.63 16.72 4 13 317 32.4 4.44 HVO_0120 signal recognition particle receptor FtsY 16.67 1 5 5 19 1.346E7 26.68 14.69 4 9 1543.24 16.67 5 10 456 48.2 4.17 HVO_0400 conserved hypothetical protein 16.67 1 2 2 8 6.213E6 7.33 16.67 2 4 556.11 16.67 2 4 126 13.9 4.68 HVO_0989 conserved hypothetical protein 16.67 1 2 2 2 2.116E6 2.56 16.67 2 2 126 14.4 4.81 HVO_1103 conserved hypothetical protein 16.67 1 4 4 22 1.954E8 26.98 13.07 3 10 1428.85 16.67 4 12 306 31.2 4.74 HVO_2056 "probable epimerase (homolog to dTDP-4-dehydrorhamnose 3,5-epimerase)" 16.67 1 3 3 8 5.650E6 2.72 10.90 2 3 591.70 16.67 3 5 156 18.3 4.55 HVO_2398 ABC-type transport system ATP-binding protein (probable substrate zinc) 16.61 1 4 4 16 7.020E6 10.57 16.61 4 8 772.63 16.61 4 8 289 30.2 4.67 HVO_A0550 receiver/sensor box histidine kinase 16.61 1 12 13 54 1.784E7 52.30 16.61 13 27 3211.47 15.59 12 27 885 95.9 4.46 HVO_0763 YphA family protein 16.57 1 1 3 23 6.797E7 10.21 9.71 2 9 1874.23 16.57 3 14 175 18.9 6.54 HVO_A0548 YphA family protein 16.57 1 1 3 20 4.094E7 10.21 9.71 2 9 1403.21 16.57 3 11 175 18.9 6.54 HVO_A0584 inosine-5'-monophosphate dehydrogenase 16.57 1 2 2 2 6.899E5 34.44 16.57 2 2 362 37.7 4.51 HVO_2381 UPF0272 family protein 16.43 1 5 5 13 1.376E7 16.88 14.40 4 6 631.66 16.43 5 7 493 52.3 4.88 HVO_0466 citrate (si)-synthase 16.36 1 5 5 26 4.484E7 38.00 16.36 5 13 1691.90 16.36 5 13 379 41.8 4.55 HVO_1823 UspA domain protein 16.34 1 2 2 4 1.561E6 4.89 16.34 2 2 183.25 16.34 2 2 153 16.4 4.60 HVO_2072 S-layer glycoprotein 16.32 1 6 6 2786 3.473E9 3240.91 16.32 6 1391 119616.31 16.32 6 1395 827 85.1 3.65 HVO_0192 conserved hypothetical protein 16.30 1 2 2 10 1.315E7 10.86 16.30 2 5 609.13 16.30 2 5 135 14.6 4.28 HVO_1245 probable disulfide bond formation protein 16.30 1 3 3 22 1.090E8 23.64 16.30 3 11 1334.89 16.30 3 11 227 24.2 4.50 HVO_2879 ornithine cyclodeaminase 16.27 1 4 4 8 2.229E7 774.11 16.27 4 8 332 34.6 4.45 HVO_A0485 aminotransferase class V 16.24 1 4 4 20 1.768E7 23.03 16.24 4 10 898.80 16.24 4 10 351 37.3 4.26 HVO_1808 conserved hypothetical protein 16.18 1 6 6 20 1.778E7 16.85 16.18 6 10 969.07 16.18 6 10 476 51.7 4.23 HVO_2500 transport protein (probable substrate cationic amino acids) 16.18 1 10 10 45 4.161E7 50.72 16.18 10 22 2445.23 16.18 10 23 748 78.6 4.61 HVO_1264 conserved hypothetical protein 16.13 1 3 3 17 2.374E7 17.36 16.13 3 9 978.43 16.13 3 8 217 23.4 4.22 HVO_2590 probable oxidoreductase (short-chain dehydrogenase family) 16.08 1 3 3 16 1.494E7 18.25 16.08 3 8 755.24 16.08 3 8 311 33.6 4.89 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 15.96 1 1 9 32 9.003E7 27.59 13.83 8 17 1790.35 12.59 7 15 564 60.0 8.00 HVO_1918 probable metallo-beta-lactamase family hydrolase 15.89 1 2 2 4 6.941E6 3.00 15.89 2 2 188.77 15.89 2 2 302 34.0 4.55 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 15.83 1 4 4 18 3.093E7 17.03 15.83 4 9 937.27 15.83 4 9 360 39.5 4.31 HVO_0601 homoserine dehydrogenase 15.82 1 3 3 30 2.889E7 50.06 15.82 3 15 2315.15 15.82 3 15 316 32.2 4.25 HVO_1806 conserved hypothetical protein 15.79 1 5 5 14 1.116E7 8.45 15.79 5 7 563.89 15.79 5 7 475 52.3 4.34 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 15.76 1 4 4 18 1.197E7 16.36 15.76 4 9 833.53 15.76 4 9 349 37.0 4.70 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 15.75 1 7 7 20 3.130E7 22.73 15.75 7 11 957.62 13.36 5 9 584 63.3 4.79 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 15.65 1 3 3 31 2.104E8 20.16 15.65 3 16 1067.94 15.65 3 15 345 37.0 3.95 HVO_1040 DnaJ domain protein 15.57 1 5 5 13 4.368E6 15.84 15.57 5 7 631.93 11.87 4 6 379 38.3 9.45 HVO_1165 mechanosensitive channel protein MscS 15.56 1 3 3 20 2.203E7 17.87 15.56 3 10 855.48 15.56 3 10 302 32.6 4.91 HVO_1554 TraB family protein 15.51 1 6 6 19 1.183E7 12.50 15.51 6 9 777.67 15.51 6 10 561 59.0 4.58 HVO_A0092 acyl-CoA dehydrogenase 15.49 1 5 5 15 7.303E6 14.00 15.49 5 7 826.32 15.49 5 8 381 42.2 4.83 HVO_C0072 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 15.49 1 4 4 19 7.769E6 16.76 13.13 3 9 1012.08 15.49 4 10 297 31.6 6.39 386849 keratin type II 15.45 1 0 8 25 9.003E7 24.07 13.32 7 13 1418.25 13.85 7 12 563 59.9 7.94 HVO_0084 transport protein (probable substrate ammonium) 15.35 1 2 2 8 1.145E8 826.41 15.35 2 8 456 47.2 5.21 HVO_1975 protein-export membrane protein SecF 15.33 1 3 3 32 1.946E8 36.26 11.15 2 14 2113.04 15.33 3 18 287 30.4 4.55 HVO_0396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 15.28 1 5 5 21 2.928E7 23.60 15.28 5 11 1325.43 15.28 5 10 360 39.2 5.01 HVO_2716 acyl-CoA dehydrogenase 15.22 1 4 4 22 1.206E7 34.54 15.22 4 11 1281.02 15.22 4 11 381 41.3 4.65 HVO_1110 ABC-type transport system periplasmic substrate-binding protein (probable substrate cobalamin) 15.18 1 3 3 24 4.630E7 34.83 15.18 3 12 2118.16 15.18 3 12 382 39.6 4.25 HVO_1553 hydroxypyruvate reductase 15.16 1 5 5 15 9.321E6 9.99 13.35 4 7 614.64 15.16 5 8 442 45.2 4.50 HVO_1867 lysine--tRNA ligase 15.14 1 6 6 19 9.387E6 17.46 13.51 5 9 924.74 15.14 6 10 555 62.1 4.46 HVO_2001 tRNA-guanine(15) transglycosylase 15.12 1 4 4 24 1.187E7 31.15 15.12 4 12 1282.66 15.12 4 12 516 56.3 4.59 HVO_2160 conserved hypothetical protein 15.11 1 21 21 722 2.243E9 907.99 15.11 21 362 45321.23 15.11 21 360 2257 232.7 3.92 HVO_1579 uridine phosphorylase 15.07 1 3 3 12 2.083E7 11.84 15.07 3 6 621.98 15.07 3 6 272 29.0 4.64 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 15.05 1 3 3 12 2.620E7 15.58 15.05 3 6 717.17 15.05 3 6 299 32.0 4.53 HVO_0429 archaemetzincin 15.03 1 2 2 6 3.455E6 8.17 15.03 2 3 345.42 15.03 2 3 173 19.3 6.54 HVO_2847 conserved hypothetical protein 15.03 1 6 6 19 7.280E6 13.96 13.21 5 8 994.10 15.03 6 11 439 50.1 4.53 HVO_0194 Orc1-type DNA replication protein 14.97 1 5 5 16 6.236E6 8.38 14.97 5 8 715.87 14.97 5 8 374 42.2 4.94 HVO_B0200 malate synthase 14.91 1 4 4 20 4.206E7 35.27 14.91 4 11 1154.28 14.91 4 9 436 48.3 4.30 HVO_1007 homolog to quinoprotein glucose dehydrogenase 14.87 1 4 4 14 1.482E7 16.50 14.87 4 7 702.03 14.87 4 7 464 48.6 4.36 HVO_0694 probable phosphoribosyltransferase 14.77 1 3 3 13 1.177E7 14.83 14.77 3 6 682.65 14.77 3 7 237 27.0 4.32 HVO_0970 ribulose-bisphosphate carboxylase large subunit 14.73 1 5 5 36 1.171E7 44.27 14.73 5 18 2159.71 14.73 5 18 414 43.9 4.59 HVO_1014 cox-type terminal oxidase subunit II 14.68 1 2 2 39 1.047E8 53.21 14.68 2 19 2468.16 14.68 2 20 252 27.7 4.59 HVO_1294 GMC family oxidoreductase 14.64 1 5 5 20 1.841E7 23.56 14.64 5 10 1064.19 14.64 5 10 526 56.7 4.94 HVO_2321 bacterial-type DNA primase DnaG 14.62 1 5 5 14 1.378E7 16.68 14.62 5 7 781.47 14.62 5 7 472 49.4 4.36 HVO_B0295 ABC-type transport system ATP-binding protein (probable substrate glycerol-3-phosphate) 14.59 1 3 4 15 2.695E7 18.11 14.59 4 8 652.77 13.53 3 7 377 41.2 4.74 HVO_2229 flavin-containing amine-oxidoreductase 14.53 1 3 3 5 7.236E7 2.54 6.10 2 2 131.57 14.53 3 3 344 37.9 4.92 HVO_1380 methylmalonyl-CoA mutase subunit A 14.52 1 4 4 13 3.610E6 4.36 14.52 4 6 432.18 14.52 4 7 558 61.9 4.41 HVO_0240 Lrp/AsnC family transcription regulator 14.47 1 2 2 8 5.620E6 6.32 14.47 2 4 402.34 14.47 2 4 152 16.9 4.39 HVO_A0159 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 14.47 1 4 4 12 1.379E7 12.32 14.47 4 6 442.04 14.47 4 6 387 42.7 4.44 HVO_2761 mevalonate kinase 14.44 1 3 3 6 3.169E6 6.08 14.44 3 3 232.16 14.44 3 3 367 38.2 4.31 HVO_2383 DNA repair and recombination protein RadB 14.41 1 2 2 8 1.294E7 7.76 14.41 2 5 263.54 14.41 2 3 229 24.6 5.02 HVO_0452 leucine--tRNA ligase 14.30 1 12 12 63 4.245E7 73.88 14.30 12 31 4065.93 14.30 12 32 958 109.5 4.37 HVO_2188 phosphoribosylformylglycinamidine synthase 1 14.29 1 3 3 10 5.839E6 11.49 14.29 3 5 501.59 14.29 3 5 224 23.9 4.36 HVO_1184 DUF1511 family protein 14.25 1 5 5 14 4.614E7 13.20 11.61 4 6 749.28 14.25 5 8 379 40.3 4.22 HVO_2637 conserved hypothetical protein 14.21 1 4 4 14 2.382E7 11.44 14.21 4 7 707.33 14.21 4 7 366 39.1 4.81 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 14.18 1 0 8 31 9.003E7 25.34 12.06 7 16 1790.35 12.59 7 15 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 14.18 1 0 8 31 9.003E7 25.34 12.06 7 16 1790.35 12.59 7 15 564 60.0 7.72 HVO_0629 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 14.16 1 4 4 20 3.486E7 23.35 14.16 4 10 1027.78 14.16 4 10 339 36.7 8.40 HVO_2419 hydroxymethylglutaryl-CoA synthase 14.16 1 5 5 24 3.486E7 21.27 14.16 5 12 1151.32 14.16 5 12 445 50.1 4.64 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 14.12 1 0 8 35 7.851E7 26.80 14.12 8 18 1441.35 14.12 8 17 432 48.1 5.02 HVO_1023 conserved hypothetical protein 14.02 1 3 3 18 2.100E7 17.31 14.02 3 9 1037.89 14.02 3 9 271 30.2 4.63 HVO_1372 pyrroline-5-carboxylate reductase 14.01 1 3 3 10 1.216E7 10.40 14.01 3 5 443.30 14.01 3 5 257 26.8 4.01 HVO_1065 Mrp-type sodium/proton antiporter system subunit E 14.00 1 2 2 12 2.239E7 17.30 14.00 2 6 584.96 14.00 2 6 200 21.7 4.68 HVO_0123 signal recognition particle 54K protein 13.98 1 6 6 24 3.287E7 27.62 11.83 5 11 1327.44 13.98 6 13 465 50.9 4.50 HVO_2883 conserved hypothetical protein 13.96 1 7 7 21 7.344E6 21.40 12.39 6 10 812.43 13.96 7 11 702 78.9 4.48 HVO_0506 ABC-type transport system ATP-binding/permease protein 13.95 1 7 7 20 2.490E7 13.43 13.95 7 11 751.03 11.47 6 9 645 71.7 4.59 HVO_2350 YyaL family protein 13.95 1 5 5 16 8.766E6 16.12 13.95 5 8 723.50 13.95 5 8 552 58.8 4.59 HVO_0020 ABC-type transport system ATP-binding protein (probable substrate thiamine) 13.85 1 3 3 12 1.317E7 11.29 13.85 3 6 600.61 13.85 3 6 361 38.3 4.79 HVO_3013 origin-associated protein OapB 13.85 1 2 2 3 6.001E6 208.90 13.85 2 3 130 14.3 4.56 HVO_A0576 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 13.79 1 4 4 24 8.243E7 30.79 13.79 4 12 1810.04 13.79 4 12 435 45.5 4.17 HVO_1175 DUF2110 family protein 13.78 1 2 2 6 2.725E7 7.51 13.78 2 3 390.24 13.78 2 3 225 24.4 4.63 HVO_0845 conserved hypothetical protein 13.77 1 3 3 10 2.133E7 10.96 13.77 3 5 486.07 13.77 3 5 276 30.0 4.16 HVO_0064 DUF296 family protein 13.67 1 2 2 4 4.149E6 2.21 13.67 2 2 133.45 13.67 2 2 139 15.6 4.37 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 13.58 1 3 3 8 7.490E6 7.83 13.58 3 4 435.05 13.58 3 4 265 28.7 4.87 HVO_1928 5-formyltetrahydrofolate cyclo-ligase 13.58 1 2 2 3 7.561E6 248.39 13.58 2 3 243 26.5 4.69 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 13.50 1 5 5 22 1.940E7 21.03 13.50 5 11 1335.66 13.50 5 11 526 57.2 4.31 HVO_1531 UDP-glucose 6-dehydrogenase 13.49 1 5 5 11 1.140E7 14.18 13.49 5 6 503.63 13.49 5 5 430 45.9 4.50 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 13.48 1 4 4 24 2.404E7 39.73 13.48 4 12 1512.18 13.48 4 12 423 43.9 4.31 HVO_A0299 ABC-type transport system periplasmic substrate-binding protein (probable substrate spermidine/putrescine) 13.43 1 3 3 23 2.847E8 17.75 13.43 3 12 799.48 13.43 3 11 469 51.0 4.11 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 13.33 1 6 6 34 1.434E7 35.46 13.33 6 16 2170.61 13.33 6 18 600 65.3 4.68 HVO_2726 glutamate--tRNA ligase 13.33 1 5 5 12 8.040E6 8.45 11.79 4 6 516.80 8.21 4 6 585 65.2 4.58 HVO_1168 "probable glycosyltransferase, type 1" 13.31 1 5 5 22 1.883E7 30.60 13.31 5 11 1604.35 13.31 5 11 353 39.1 5.01 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 13.25 1 0 5 22 7.766E7 12.91 8.25 4 11 832.28 13.25 5 11 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 13.25 1 0 5 22 7.766E7 12.91 8.25 4 11 832.28 13.25 5 11 400 44.1 5.14 HVO_B0101 IclR family transcription regulator 13.23 1 3 3 7 3.377E6 6.47 13.23 3 4 225.32 13.23 3 3 257 28.6 5.02 HVO_2614 uridine phosphorylase 13.22 1 3 3 43 1.804E8 61.48 13.22 3 23 3099.17 13.22 3 20 242 25.8 4.30 HVO_0907 cox-type terminal oxidase subunit I 13.19 1 6 6 37 1.166E8 23.51 13.19 6 18 1838.54 13.19 6 19 599 65.7 5.11 HVO_A0295_A luciferase family protein 13.18 1 3 3 18 1.776E7 13.36 13.18 3 9 624.66 13.18 3 9 349 38.5 4.67 HVO_0086 transport protein (probable substrate ammonium) 13.06 1 3 3 16 7.282E7 11.80 13.06 3 8 602.54 13.06 3 8 467 47.4 4.50 HVO_1309 peptidase M24 family protein 13.04 1 3 3 5 7.579E6 4.95 13.04 3 3 209.67 4.86 2 2 391 42.1 4.36 HVO_2529 probable oxidoreductase (short-chain dehydrogenase family) 13.04 1 2 2 6 1.248E7 6.86 13.04 2 3 249.89 13.04 2 3 230 23.6 4.72 HVO_1413 probable NADH dehydrogenase 13.00 1 3 3 16 6.049E6 10.74 13.00 3 8 527.81 13.00 3 8 377 39.7 4.67 HVO_B0078 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 12.92 1 4 4 8 2.446E7 10.48 9.55 3 4 362.21 9.83 3 4 356 39.0 4.81 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 12.88 1 1 8 39 7.764E7 31.05 12.88 8 21 2056.93 9.83 6 18 590 62.4 8.06 HVO_1446 "fructose-1,6-bisphosphatase" 12.79 1 2 2 8 6.428E6 7.43 12.79 2 4 290.44 12.79 2 4 297 31.6 4.45 HVO_2998 homoserine O-acetyltransferase 12.77 1 3 3 8 5.982E6 8.62 12.77 3 4 352.12 12.77 3 4 415 44.8 4.69 HVO_1654 cysteine synthase 12.75 1 3 3 10 5.867E6 9.95 12.75 3 5 414.00 12.75 3 5 306 32.3 4.32 HVO_1258 conserved hypothetical protein 12.70 1 4 4 14 8.011E6 10.28 12.70 4 7 580.11 12.70 4 7 307 31.8 4.23 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 12.70 1 2 2 3 1.396E7 253.96 12.70 2 3 189 21.7 4.46 HVO_1981 hypothetical protein 12.69 1 2 2 14 3.603E6 11.14 12.69 2 6 770.77 12.69 2 8 197 20.3 4.01 HVO_B0300 uricase 12.66 1 3 3 14 7.065E6 9.56 12.66 3 7 440.73 12.66 3 7 308 34.4 4.20 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 12.65 1 3 3 16 1.142E7 19.96 12.65 3 8 898.72 12.65 3 8 324 33.6 3.99 HVO_2164 ABC-type transport system permease protein (homolog to LolDCE lipoprotein release factor) 12.65 1 5 5 47 9.670E7 36.98 12.65 5 23 2432.87 12.65 5 24 411 42.1 4.72 HVO_0296 probable oxidoreductase (short-chain dehydrogenase family) 12.64 1 3 3 22 8.524E6 24.97 12.64 3 11 1310.81 12.64 3 11 261 27.0 4.44 HVO_0889 FAD-dependent oxidoreductase 12.62 1 2 2 20 9.029E6 26.91 12.62 2 10 1523.70 12.62 2 10 214 21.8 3.89 HVO_1083 glucose 1-dehydrogenase 12.61 1 3 3 6 2.582E6 1.90 12.61 3 3 219.80 12.61 3 3 357 39.0 4.73 HVO_2266 hypothetical protein 12.58 1 5 5 48 2.340E7 43.16 12.58 5 24 2659.01 12.58 5 24 493 56.7 4.54 HVO_0214 L-lactate dehydrogenase 12.50 1 3 3 20 7.827E7 23.64 12.50 3 10 986.52 12.50 3 10 320 34.5 4.49 HVO_1441 ABC-type transport system permease protein 12.50 1 2 2 7 6.143E6 9.74 12.50 2 4 354.80 12.50 2 3 352 36.7 4.96 HVO_1523_A glycosyltransferase AglE 12.50 1 3 3 11 9.054E6 6.10 5.26 2 5 527.01 12.50 3 6 304 33.8 7.08 HVO_0995 conserved hypothetical protein 12.46 1 4 4 49 4.672E7 30.86 12.46 4 24 2136.53 12.46 4 25 345 35.9 4.96 HVO_1650 polyphosphate kinase 12.38 1 8 8 33 1.301E7 29.31 12.38 8 16 1641.63 12.38 8 17 832 93.6 4.65 HVO_0655 NAD-dependent epimerase/dehydratase 12.32 1 4 4 16 1.403E7 14.31 12.32 4 8 1112.85 12.32 4 8 341 36.9 4.74 HVO_A0451 transport protein (probable substrate arsenite/antimonite) 12.32 1 7 7 24 1.754E7 28.81 12.32 7 12 1579.24 12.32 7 12 641 68.3 4.60 HVO_0661 dCTP deaminase (dUMP-forming) 12.31 1 2 2 6 6.199E6 8.62 12.31 2 3 381.12 12.31 2 3 195 21.2 4.59 HVO_A0559 histidine ammonia-lyase 12.31 1 6 6 17 1.087E7 15.61 12.31 6 9 790.72 10.98 5 8 528 55.5 4.84 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 12.27 1 3 3 12 1.143E7 13.99 12.27 3 6 481.45 12.27 3 6 383 42.0 4.49 HVO_1741 conserved hypothetical protein 12.20 1 3 3 11 4.213E6 0.00 12.20 3 5 297.64 12.20 3 6 328 37.6 4.46 HVO_A0181 conserved hypothetical protein 12.18 1 2 2 10 2.199E7 13.53 12.18 2 5 709.13 12.18 2 5 238 25.1 3.93 HVO_2172 conserved hypothetical protein 12.15 1 6 6 31 1.727E7 37.70 12.15 6 15 1855.81 12.15 6 16 741 75.2 4.27 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 12.13 1 2 2 4 7.452E6 2.52 12.13 2 2 138.89 12.13 2 2 305 34.1 4.91 HVO_2203 conserved hypothetical protein 12.12 1 2 2 18 2.107E7 18.78 12.12 2 10 791.57 12.12 2 8 264 28.4 4.20 HVO_A0300 ABC-type transport system permease protein (probable substrate spermidine/putrescine) 12.08 1 3 3 14 4.768E7 6.48 6.71 2 4 1386.54 12.08 3 10 298 32.7 4.45 HVO_1256 conserved hypothetical protein 12.04 1 2 2 6 7.855E6 5.14 12.04 2 3 328.35 12.04 2 3 299 33.0 4.65 HVO_1357 receiver/bat box HTH-10 family transcription regulator 12.03 1 4 4 8 8.750E6 11.24 12.03 4 5 238.18 5.50 2 3 582 62.7 4.40 HVO_2521 DUF21/CBS domain protein 12.03 1 3 3 18 4.724E7 23.78 12.03 3 9 1434.35 12.03 3 9 349 38.4 4.42 HVO_1249 conserved hypothetical protein 11.97 1 2 2 2 5.830E5 0.00 11.97 2 2 142 16.4 5.20 HVO_0237 UPF0761 family protein 11.91 1 4 4 49 3.089E7 79.38 11.91 4 25 4473.72 11.91 4 24 445 46.7 5.14 HVO_1295 histidinol-phosphate aminotransferase 11.91 1 3 3 10 4.810E6 15.33 11.91 3 5 590.25 11.91 3 5 361 39.4 4.51 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 11.90 1 4 4 11 1.509E7 5.62 9.07 3 5 432.37 11.90 4 6 353 36.7 4.65 HVO_B0345 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 11.90 1 4 4 18 1.472E7 13.29 11.90 4 9 795.38 11.90 4 9 378 41.2 4.84 HVO_1281 "probable glycosyltransferase, type 1" 11.76 1 3 3 14 5.746E6 12.73 11.76 3 7 768.39 11.76 3 7 357 38.7 5.87 HVO_0842 cytochrome bc1 complex cytochrome b subunit 11.74 1 4 4 8 2.568E6 3.59 11.74 4 4 300.25 11.74 4 4 264 30.5 6.89 HVO_1868 conserved hypothetical protein 11.73 1 2 2 4 5.015E6 4.99 11.73 2 2 220.14 11.73 2 2 179 20.0 5.38 HVO_2882 DUF4013 family protein 11.67 1 2 2 19 1.423E8 21.11 11.67 2 9 1187.80 11.67 2 10 240 25.4 4.55 HVO_0158 TATA-binding transcription initiation factor 11.64 1 2 2 10 2.083E7 11.86 11.64 2 5 846.54 11.64 2 5 189 20.3 4.22 4557890 keratin 5 [Homo sapiens] 11.53 1 0 7 37 7.764E7 31.05 11.53 7 20 1979.38 8.47 5 17 590 62.4 8.06 HVO_0865 FkbM family methyltransferase 11.51 1 3 3 10 3.282E7 13.24 11.51 3 5 697.37 11.51 3 5 252 27.7 5.49 HVO_1567 conserved hypothetical protein 11.49 1 2 2 6 5.442E6 5.53 11.49 2 3 313.38 11.49 2 3 235 25.7 4.36 HVO_0162 peptidase M48 family protein 11.48 1 4 4 14 3.274E7 13.80 11.48 4 7 739.23 11.48 4 7 366 39.0 9.39 HVO_1095 conserved hypothetical protein 11.41 1 2 2 8 6.526E6 8.00 11.41 2 4 463.89 11.41 2 4 184 18.8 4.87 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 11.40 1 3 3 8 1.794E7 8.90 11.40 3 4 410.09 11.40 3 4 430 45.1 4.50 HVO_1337 rpa-associated protein 11.40 1 4 4 18 2.820E7 15.83 11.40 4 9 813.66 11.40 4 9 623 64.8 3.68 HVO_2173 DUF1616 family protein 11.38 1 3 3 13 1.255E7 12.57 8.68 2 6 473.31 11.38 3 7 334 36.6 4.92 HVO_1371 glutamate 5-kinase 11.30 1 3 3 21 8.253E6 13.59 11.30 3 10 1014.40 11.30 3 11 301 32.0 4.25 HVO_A0160 sensor box histidine kinase 11.30 1 5 5 18 9.082E6 19.93 11.30 5 9 1191.71 11.30 5 9 708 76.5 4.79 HVO_B0233 alpha-L-arabinofuranosidase 11.15 1 5 5 22 4.940E6 19.75 11.15 5 11 1103.44 11.15 5 11 511 57.5 4.39 HVO_2692 ABC-type transport system ATP-binding protein (probable substrate sugar) 11.14 1 3 3 18 1.488E7 13.97 11.14 3 9 910.82 11.14 3 9 395 43.3 4.37 HVO_0853 DNA double-strand break repair protein Mre11 11.11 1 3 3 17 7.882E6 26.70 6.80 2 8 1334.89 11.11 3 9 441 48.1 4.39 HVO_2711 DoxX domain protein 11.08 1 4 4 17 3.081E7 9.83 11.08 4 8 804.86 11.08 4 9 370 38.1 7.06 HVO_A0047 UspA domain protein 11.07 1 3 3 14 8.778E6 14.60 11.07 3 7 647.31 11.07 3 7 289 30.8 4.53 HVO_2536 CHP00300 family protein 11.06 1 2 2 10 1.160E7 2.62 11.06 2 5 387.11 11.06 2 5 416 44.8 4.51 HVO_2913 superoxide dismutase (Mn) 11.06 1 0 2 24 3.949E8 31.21 11.06 2 11 1591.00 11.06 2 13 199 22.3 4.48 HVO_1542 conserved hypothetical protein 11.02 1 2 2 22 5.928E7 32.06 11.02 2 11 1599.66 11.02 2 11 354 36.1 5.48 HVO_1338 replication protein A 11.01 1 4 4 17 9.449E6 16.77 11.01 4 9 807.15 11.01 4 8 427 46.0 4.36 HVO_A0475 superoxide dismutase (Mn) 11.00 1 0 2 24 3.949E8 31.21 11.00 2 11 1591.00 11.00 2 13 200 22.4 4.45 HVO_0138 tyrosine--tRNA ligase 10.98 1 3 3 14 1.294E7 12.51 10.98 3 7 740.78 10.98 3 7 328 36.1 4.34 HVO_2187 CHP01210 family protein 10.83 1 3 3 16 2.067E7 13.79 10.83 3 8 731.79 10.83 3 8 360 40.0 4.58 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 10.81 1 4 4 12 4.198E6 8.14 10.81 4 6 564.93 10.81 4 6 444 47.1 4.77 HVO_2079 RND superfamily permease 10.80 1 7 7 28 1.179E7 24.10 10.80 7 14 1520.81 10.80 7 14 750 80.5 4.96 HVO_B0182 deoxyhypusine synthase 10.80 1 3 3 10 9.646E6 3.98 10.80 3 5 371.05 10.80 3 5 324 35.6 4.30 HVO_1585 acyl-CoA synthetase 10.78 1 5 5 7 6.288E6 6.05 6.14 3 3 297.53 9.28 4 4 668 74.1 4.48 HVO_A0629 sensor box histidine kinase 10.77 1 4 4 11 5.106E6 15.68 8.03 3 5 895.57 10.77 4 6 548 59.9 4.63 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 10.75 1 0 5 21 7.664E7 10.54 10.75 5 11 832.67 10.75 5 10 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 10.75 1 0 5 21 7.664E7 10.54 10.75 5 11 832.67 10.75 5 10 456 49.2 4.77 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 10.74 1 3 3 10 6.138E6 8.90 10.74 3 5 588.64 10.74 3 5 363 39.3 4.97 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 10.74 1 2 2 6 6.689E6 6.34 10.74 2 3 251.11 10.74 2 3 270 29.1 4.35 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 10.68 1 3 3 8 3.912E6 9.30 10.68 3 4 416.03 10.68 3 4 365 39.0 4.61 HVO_2125 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 10.66 1 3 3 16 1.166E7 22.82 10.66 3 8 951.44 10.66 3 8 319 34.9 8.92 HVO_0968 NADH dehydrogenase-like complex subunit CD 10.64 1 0 7 71 3.887E8 84.39 10.64 7 34 5509.57 9.57 6 37 564 63.3 4.60 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 10.58 1 4 4 10 5.048E6 10.03 8.47 3 4 500.60 10.58 4 6 378 39.8 4.45 HVO_1059 conserved hypothetical protein 10.56 1 2 2 6 2.386E6 2.12 10.56 2 2 302.50 10.56 2 4 180 20.6 4.97 HVO_1112 ABC-type transport system ATP-binding protein (probable substrate cobalamin) 10.50 1 3 3 12 1.022E7 19.50 10.50 3 6 992.09 10.50 3 6 476 49.4 4.55 HVO_A0269 glycerol-3-phosphate dehydrogenase subunit A 10.48 1 2 2 2 3.010E6 2.13 10.48 2 2 563 60.9 4.73 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 10.44 1 2 2 6 3.117E7 8.05 10.44 2 3 210.60 10.44 2 3 297 31.3 4.36 HVO_2873 flap endonuclease Fen1 10.43 1 2 2 16 1.351E7 19.33 10.43 2 8 718.82 10.43 2 8 326 36.4 4.40 HVO_0933 P-type transport ATPase (probable substrate copper/metal cation) 10.39 1 6 6 23 1.288E7 28.29 7.74 5 11 1316.22 10.39 6 12 943 99.2 4.55 HVO_2256 DUF262 family protein 10.39 1 5 5 13 7.282E6 12.77 10.39 5 7 615.85 10.39 5 6 462 54.9 4.89 HVO_1098 diaminopimelate decarboxylase 10.36 1 4 4 15 1.359E7 6.30 10.36 4 8 652.83 10.36 4 7 415 44.4 5.02 HVO_A0562 urocanate hydratase 10.32 1 4 4 11 2.232E7 5.04 8.55 3 5 436.75 10.32 4 6 620 67.9 4.70 HVO_1527 glucose-1-phosphate uridylyltransferase 10.29 1 2 2 8 1.088E7 4.16 10.29 2 4 295.26 10.29 2 4 243 27.5 4.70 HVO_0711 conserved hypothetical protein 10.19 1 3 3 18 5.242E7 16.15 10.19 3 9 987.80 10.19 3 9 216 23.1 3.81 HVO_0699 translation initiation factor aIF-2 alpha subunit 10.15 1 2 2 11 1.428E7 11.89 10.15 2 5 584.09 10.15 2 6 266 29.5 4.46 HVO_0322 MinD/ParA domain protein 10.15 1 3 3 14 1.776E7 17.97 10.15 3 7 888.52 10.15 3 7 581 58.8 3.70 HVO_0727 rhomboid family protein 10.14 1 2 2 12 1.784E7 6.64 10.14 2 6 411.93 10.14 2 6 296 31.7 7.12 HVO_1866 uridylate kinase 10.13 1 2 2 14 1.086E7 17.93 10.13 2 7 794.71 10.13 2 7 237 24.6 4.42 HVO_1344 SBDS family protein 10.08 1 2 2 4 5.180E6 6.82 10.08 2 2 245.50 10.08 2 2 238 26.5 4.51 HVO_1398 ABC-type transport system permease protein (probable substrate sugar) 10.08 1 3 3 14 9.847E6 15.36 7.63 2 6 730.27 10.08 3 8 367 38.4 6.57 HVO_B0106 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 10.04 1 3 3 15 7.646E6 20.28 10.04 3 8 852.18 5.74 2 7 488 52.6 4.13 HVO_0867 HD family hydrolase 10.00 1 2 2 4 2.072E6 3.24 10.00 2 2 168.89 10.00 2 2 230 26.2 4.78 HVO_1129 conserved hypothetical protein 10.00 1 2 2 8 1.555E7 9.45 10.00 2 4 372.63 10.00 2 4 390 43.0 4.44 HVO_A0586 sugar nucleotidyltransferase 9.98 1 3 3 12 1.631E7 16.03 9.98 3 6 601.52 9.98 3 6 411 43.7 4.69 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 9.92 1 4 4 16 2.276E7 15.49 9.92 4 8 726.16 9.92 4 8 373 40.2 4.44 HVO_0986 NADH dehydrogenase-like complex subunit L 9.88 1 6 6 43 1.433E8 39.15 9.88 6 22 2165.11 9.88 6 21 678 71.7 6.14 HVO_0988 NADH dehydrogenase-like complex subunit N 9.88 1 3 3 14 4.391E7 13.75 9.88 3 7 916.23 9.88 3 7 506 52.2 4.64 HVO_0408 PrsW family protein 9.86 1 2 2 10 1.040E7 17.27 9.86 2 5 772.35 9.86 2 5 345 35.7 4.83 HVO_A0522 acetyl-CoA C-acyltransferase 9.82 1 2 2 6 4.671E6 8.78 9.82 2 3 270.15 9.82 2 3 387 39.2 4.77 HVO_2501 alpha/beta hydrolase fold protein 9.81 1 2 2 3 1.568E7 7.09 9.81 2 3 316 35.3 5.72 HVO_2871 pyridoxal phosphate-dependent aminotransferase 9.78 1 3 3 14 6.803E6 22.26 9.78 3 7 986.84 9.78 3 7 450 49.1 4.70 HVO_0744 homolog to carboxylate-amine ligase 9.76 1 3 3 12 1.263E7 1.80 9.76 3 5 432.02 9.76 3 7 369 41.7 4.88 HVO_0893 methylmalonyl-CoA mutase subunit A 9.72 1 3 3 10 4.183E6 14.01 9.72 3 5 422.33 9.72 3 5 566 63.1 4.36 HVO_0558 SAMP-activating enzyme E1 9.63 1 2 2 2 5.724E6 4.57 9.63 2 2 270 28.7 4.35 HVO_0975 homolog to membrane-bound mannosyltransferase 9.59 1 5 5 18 3.668E7 18.69 9.59 5 9 1005.05 9.59 5 9 584 62.8 4.97 HVO_0913 MATE efflux family protein 9.58 1 4 4 12 4.175E6 5.25 9.58 4 6 314.59 9.58 4 6 480 49.7 5.16 HVO_1284 GTP cyclohydrolase III 9.58 1 2 2 7 1.010E7 9.78 9.58 2 4 624.93 9.58 2 3 261 28.9 4.70 HVO_1657 phosphoribosylamine--glycine ligase 9.58 1 4 4 16 4.058E7 13.18 6.78 3 7 934.64 9.58 4 9 428 45.5 4.20 HVO_2884 conserved hypothetical protein 9.56 1 3 3 12 1.170E7 7.26 9.56 3 5 691.43 9.56 3 7 450 46.7 5.17 HVO_3010 ATP-dependent RNA helicase/nuclease Hef 9.56 1 6 6 16 8.198E6 16.15 9.56 6 8 695.48 9.56 6 8 858 93.9 4.69 HVO_0564 ABC-type transport system periplasmic substrate-binding protein (probable substrate maltose) 9.49 1 3 3 12 2.220E7 19.13 9.49 3 6 876.88 9.49 3 6 432 46.8 4.18 HVO_1972 GNAT family acetyltransferase 9.48 1 2 2 10 6.946E6 9.32 9.48 2 5 569.94 9.48 2 5 211 23.3 6.02 HVO_0044 acetylglutamate kinase 9.48 1 2 2 3 2.986E7 240.04 9.48 2 3 327 33.2 4.49 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 9.40 1 2 2 4 6.753E6 4.53 9.40 2 2 238.11 9.40 2 2 266 29.7 4.32 HVO_1589 molecular chaperone DnaJ 9.35 1 3 3 12 1.749E7 10.43 6.23 2 5 824.48 9.35 3 7 385 41.9 4.97 HVO_B0064 conserved hypothetical protein 9.35 1 2 2 48 3.104E8 65.64 9.35 2 24 3075.41 9.35 2 24 278 28.1 5.47 HVO_0835 acetyl-CoA C-acetyltransferase 9.28 1 3 3 8 1.499E7 8.01 9.28 3 4 287.81 9.28 3 4 388 40.1 4.78 HVO_1594 tRNA/rRNA cytosine-C5-methylase 9.27 1 2 2 6 8.984E6 8.69 9.27 2 3 361.31 9.27 2 3 313 34.6 4.69 HVO_0321 peptide chain release factor aRF-1 9.18 1 3 3 14 5.633E6 11.31 9.18 3 7 464.07 9.18 3 7 414 46.6 4.83 HVO_0981 NADH dehydrogenase-like complex subunit H 9.17 1 4 4 17 9.907E7 19.87 9.17 4 9 1035.13 9.17 4 8 349 36.9 5.19 HVO_1735 conserved hypothetical protein 9.09 1 5 5 20 1.149E7 21.98 9.09 5 10 1016.05 9.09 5 10 660 75.7 4.50 HVO_1816 dihydroorotase 9.09 1 3 3 7 7.955E6 10.56 9.09 3 4 426.46 9.09 3 3 429 45.4 4.40 HVO_2530 homolog to phosphoribosylamine--glycine ligase 9.09 1 4 4 12 8.702E6 10.66 9.09 4 6 632.09 9.09 4 6 440 49.8 4.70 HVO_B0138 PQQ repeat protein 9.09 1 3 3 9 8.641E6 9.40 9.09 3 4 348.49 9.09 3 5 407 42.6 4.93 HVO_1870 probable metalloprotease 9.08 1 5 5 24 4.751E7 18.65 9.08 5 12 1354.90 9.08 5 12 595 62.0 4.84 HVO_1033 type IV pilus biogenesis complex membrane subunit 9.05 1 4 4 18 5.847E6 22.61 9.05 4 9 1246.43 9.05 4 9 707 76.1 5.41 HVO_0191 DNA mismatch repair protein MutS 9.04 1 3 3 7 2.313E7 0.00 9.04 3 4 115.56 6.17 2 3 664 70.7 4.46 HVO_1135 conserved hypothetical protein 8.97 1 2 2 6 5.317E6 3.01 8.97 2 3 234.63 8.97 2 3 301 32.8 5.15 HVO_1375 O-succinylbenzoic acid--CoA ligase 8.96 1 4 4 12 8.488E6 12.71 8.96 4 6 489.03 8.96 4 6 614 64.7 4.28 HVO_1479 CHP03663 family protein 8.96 1 3 3 10 2.772E7 12.74 8.96 3 5 690.79 8.96 3 5 547 57.3 5.99 HVO_A0611 ABC-type transport system periplasmic substrate-binding protein (probable substrate zinc) 8.96 1 3 3 10 6.388E6 4.72 8.96 3 5 365.86 8.96 3 5 335 35.9 4.39 HVO_1412 diphosphomevalonate decarboxylase 8.95 1 3 3 18 6.940E7 12.92 8.95 3 9 973.64 8.95 3 9 324 35.4 4.78 HVO_C0043 conserved hypothetical protein 8.93 1 4 4 10 8.558E6 12.25 8.93 4 5 441.04 8.93 4 5 661 73.8 4.75 HVO_2448 probable oxidoreductase (aldo-keto reductase family protein) 8.87 1 3 3 9 1.204E7 5.26 6.12 2 4 512.70 8.87 3 5 327 36.5 4.94 HVO_2763 homolog to ribonuclease Z 8.87 1 2 2 6 1.020E7 0.00 8.87 2 3 205.42 8.87 2 3 248 26.6 4.53 HVO_1055 TrkA domain protein 8.85 1 2 2 8 7.425E6 7.92 8.85 2 4 394.29 8.85 2 4 226 24.4 4.39 HVO_0185 twin arginine translocation system subunit TatCt 8.77 1 5 5 18 2.435E7 22.31 8.77 5 9 1104.50 8.77 5 9 718 77.9 4.94 HVO_A0097 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 8.77 1 2 2 3 4.526E6 173.10 8.77 2 3 650 70.2 4.27 HVO_A0296 probable oxidoreductase (short-chain dehydrogenase family) 8.76 1 2 2 6 7.561E6 2.16 8.76 2 3 383.88 8.76 2 3 251 26.1 4.72 HVO_B0038A D-xylonate dehydratase 8.74 1 0 4 38 3.644E8 27.89 8.74 4 20 1595.80 5.10 3 18 412 45.5 4.55 27894337 keratin 20 [Homo sapiens] 8.73 1 1 3 5 2.508E7 4.96 2.59 2 2 263.77 8.73 3 3 424 48.5 5.69 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 8.72 1 2 2 10 1.436E7 17.31 8.72 2 5 702.19 8.72 2 5 344 37.0 4.55 HVO_B0135 conserved hypothetical protein 8.68 1 2 2 4 1.012E8 481.56 8.68 2 4 288 28.9 8.81 HVO_1139 squalene synthase 8.66 1 2 2 6 1.001E7 3.89 8.66 2 3 264.46 8.66 2 3 358 39.7 4.54 HVO_2228 PHP domain protein 8.65 1 2 2 8 7.721E6 8.92 8.65 2 4 423.70 8.65 2 4 289 31.2 9.82 HVO_2921 conserved hypothetical protein 8.50 1 2 2 15 6.481E6 9.55 8.50 2 8 657.74 8.50 2 7 306 32.7 4.34 HVO_1941 AAA-type ATPase (MoxR subfamily) 8.49 1 2 2 5 1.299E7 7.15 8.49 2 3 191.24 8.49 2 2 318 34.8 4.83 HVO_3001 ABC-type transport system permease protein 8.47 1 2 2 8 2.691E7 11.00 8.47 2 4 486.35 8.47 2 4 307 33.0 9.69 HVO_2322 YfiH family protein 8.43 1 2 2 6 5.665E6 8.04 8.43 2 3 410.98 8.43 2 3 249 26.8 4.34 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 8.37 1 2 2 6 2.959E7 8.49 8.37 2 3 266.33 8.37 2 3 430 44.2 4.37 HVO_0552 DNA mismatch repair protein MutS 8.33 1 6 6 22 1.991E7 21.59 8.33 6 11 1208.77 8.33 6 11 924 99.2 4.65 HVO_0941 conserved hypothetical protein 8.33 1 2 2 3 2.191E7 5.27 8.33 2 3 264 27.3 9.72 HVO_0945 ba3-type terminal oxidase subunit I 8.32 1 3 3 19 5.708E7 16.79 8.32 3 10 1083.34 2.72 2 9 589 64.3 6.71 HVO_B0029 xylose dehydrogenase (NADP) 8.31 1 2 2 10 6.480E6 10.33 8.31 2 5 411.29 8.31 2 5 325 34.7 4.39 HVO_0244 transport protein (probable substrate zinc/cadmium) 8.28 1 2 2 10 2.863E7 11.88 8.28 2 5 499.26 8.28 2 5 314 34.0 4.60 HVO_0462 cytochrome bd ubiquinol oxidase subunit I 8.23 1 3 3 8 6.155E6 9.16 8.23 3 4 363.47 8.23 3 4 474 52.1 4.77 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 8.23 1 2 2 7 5.321E6 7.54 8.23 2 3 463.62 8.23 2 4 231 25.0 4.25 HVO_1862 probable metalloprotease 8.18 1 2 2 14 8.092E6 21.08 8.18 2 7 796.65 8.18 2 7 379 40.9 5.21 HVO_1528 glycosyltransferase AglI 8.14 1 2 2 8 2.069E7 8.48 8.14 2 4 405.38 8.14 2 4 295 32.8 4.72 HVO_1926 SIMPL domain protein 8.00 1 2 2 4 2.294E6 1.94 8.00 2 2 156.93 8.00 2 2 250 25.3 4.34 HVO_2861 conserved hypothetical protein 8.00 1 2 2 4 5.906E6 3.75 8.00 2 2 141.89 8.00 2 2 275 29.1 4.27 HVO_1936 F420-0:gamma-glutamyl ligase 7.97 1 2 2 4 2.081E6 1.62 7.97 2 2 96.17 7.97 2 2 251 27.4 4.68 HVO_0896 acyl-CoA synthetase 7.96 1 3 3 8 3.352E6 7.97 7.96 3 4 297.41 7.96 3 4 540 59.8 4.56 HVO_2571 UPF0761 family protein 7.95 1 3 3 8 1.811E7 4.63 7.95 3 4 279.69 7.95 3 4 352 37.9 4.60 HVO_B0318 ABC-type transport system periplasmic substrate-binding protein (substrate glucose) 7.93 1 3 3 6 7.580E7 4.27 7.93 3 3 347.64 7.93 3 3 391 42.4 3.95 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 7.92 1 3 3 8 5.227E6 6.36 5.80 2 3 575.53 7.92 3 5 379 41.7 4.83 HVO_0406 RNA-binding protein AU-1 7.91 1 2 2 4 1.701E7 5.76 7.91 2 2 158.11 7.91 2 2 468 49.9 4.53 HVO_2298 UPF0135 family protein 7.91 1 2 2 10 9.491E6 12.62 7.91 2 5 531.81 7.91 2 5 253 26.5 4.37 HVO_0197 PurE family protein 7.91 1 2 2 2 3.881E6 161.48 7.91 2 2 253 25.5 4.42 HVO_0739 conserved hypothetical protein 7.90 1 2 2 12 2.621E7 16.73 7.90 2 6 815.51 7.90 2 6 329 33.5 4.97 HVO_0760 "probable glycosyltransferase, type 2" 7.88 1 3 3 9 2.492E6 9.08 7.88 3 4 441.44 7.88 3 5 368 40.7 4.82 HVO_B0143 receiver/sensor box histidine kinase 7.87 1 4 4 12 7.113E6 15.71 7.87 4 6 647.89 7.87 4 6 597 66.0 4.41 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 7.87 1 2 2 3 1.226E6 245.82 7.87 2 3 254 26.9 4.42 HVO_1356 sensor box histidine kinase 7.82 1 3 3 12 9.280E6 3.69 7.82 3 6 487.99 7.82 3 6 550 61.1 4.60 HVO_2324 SSSF family transport protein 7.82 1 3 3 26 9.826E7 33.81 7.82 3 13 1517.81 7.82 3 13 499 52.9 6.60 HVO_0328 NAD-dependent epimerase/dehydratase 7.77 1 2 2 4 3.063E6 2.60 7.77 2 2 128.47 7.77 2 2 296 31.7 5.07 HVO_1394 probable NhaC-type sodium/proton antiporter 7.75 1 4 4 11 2.046E7 6.50 5.62 3 4 783.35 7.75 4 7 516 53.0 4.84 HVO_0292 replication protein A 7.72 1 2 2 6 6.510E6 6.31 7.72 2 3 149.98 7.72 2 3 311 34.6 4.31 HVO_2130 IclR family transcription regulator 7.72 1 2 2 6 6.082E6 6.84 7.72 2 3 357.98 7.72 2 3 272 30.1 5.55 HVO_0818 threonine synthase 7.71 1 3 3 13 2.061E7 7.87 7.71 3 6 608.62 7.71 3 7 389 40.8 4.31 HVO_1128 sirohydrochlorin cobaltochelatase 7.53 1 2 2 4 5.346E6 0.00 7.53 2 2 128.33 7.53 2 2 292 32.3 4.42 HVO_2161 conserved hypothetical protein 7.52 1 3 3 31 6.445E7 34.53 7.52 3 16 1711.19 7.52 3 15 359 36.7 3.88 HVO_1943 endoisopeptidase/DUF4129 domain protein 7.51 1 5 5 14 2.478E6 12.52 7.51 5 7 786.20 7.51 5 7 746 78.9 4.65 HVO_1510 2-isopropylmalate synthase 7.50 1 2 2 8 2.667E7 8.64 7.50 2 4 473.33 7.50 2 4 440 47.7 4.82 HVO_2211 TrkA domain protein 7.49 1 2 2 8 1.164E7 7.80 7.49 2 4 352.98 7.49 2 4 227 24.5 4.72 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 7.44 1 2 2 4 2.245E7 1.97 7.44 2 2 148.20 7.44 2 2 363 39.7 4.25 HVO_0022 ABC-type transport system periplasmic substrate-binding protein (probable substrate thiamine) 7.41 1 2 2 4 3.546E6 4.24 7.41 2 2 113.02 7.41 2 2 378 41.1 4.20 HVO_0043 acetylornithine aminotransferase 7.41 1 2 2 12 1.749E7 16.58 7.41 2 6 869.64 7.41 2 6 378 39.7 4.67 HVO_0766 Hsp20-type molecular chaperone 7.41 1 1 2 2 8.435E5 161.50 7.41 2 2 162 17.7 4.39 HVO_0984 NADH dehydrogenase-like complex subunit J2 7.38 1 2 2 4 6.120E4 0.00 7.38 2 2 127.53 7.38 2 2 122 12.8 4.54 HVO_0420 transducer protein MpcT 7.37 1 2 2 4 6.148E6 6.00 7.37 2 2 281.43 7.37 2 2 543 57.1 4.12 HVO_2171 DUF58 family protein 7.37 1 3 3 12 1.063E7 12.81 7.37 3 6 724.34 7.37 3 6 475 50.8 4.93 HVO_B0354 conserved hypothetical protein 7.30 1 6 6 20 1.334E7 16.99 7.30 6 10 1136.55 7.30 6 10 767 85.4 4.68 HVO_0987 NADH dehydrogenase-like complex subunit M 7.27 1 4 4 21 1.230E8 10.91 7.27 4 10 945.11 7.27 4 11 509 54.7 5.08 HVO_2881 DUF4013 family protein 7.06 1 2 2 4 4.081E7 2.40 7.06 2 2 246.86 7.06 2 2 255 27.5 4.79 HVO_A0635 probable cysteine desulfurase 7.01 1 2 2 4 3.118E6 4.19 7.01 2 2 187.35 7.01 2 2 371 40.4 4.53 HVO_0702 DUF2298 family protein 6.99 1 5 5 20 1.493E7 26.48 6.99 5 10 1254.95 6.99 5 10 787 82.8 6.04 HVO_B0021 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 6.99 1 4 4 10 5.118E6 10.11 6.99 4 5 498.67 6.99 4 5 644 70.6 4.56 HVO_2946 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 6.98 1 2 2 8 1.142E7 8.26 6.98 2 4 325.72 6.98 2 4 401 43.1 4.60 HVO_B0025 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 6.94 1 1 2 2 2.828E6 123.72 6.94 2 2 346 37.2 4.53 HVO_0882 DUF373 family protein 6.88 1 3 3 10 6.544E6 6.90 6.88 3 5 466.06 6.88 3 5 378 40.2 4.55 HVO_1399 ABC-type transport system permease protein (probable substrate sugar) 6.87 1 2 2 4 2.041E6 508.61 6.87 2 4 422 43.8 4.64 HVO_0102 HtpX-like protease 6.83 1 2 2 10 1.750E7 6.68 6.83 2 5 449.05 6.83 2 5 293 32.7 7.50 HVO_B0139 PQQ repeat protein 6.76 1 2 2 8 8.660E6 10.45 6.76 2 4 727.70 6.76 2 4 429 44.6 4.93 HVO_2071 conserved hypothetical protein 6.74 1 3 3 12 1.420E7 11.49 6.74 3 7 535.33 6.74 3 5 549 58.4 4.72 HVO_2639 DUF1611 family protein 6.74 1 2 2 4 8.640E6 2.32 6.74 2 2 187.19 6.74 2 2 341 36.3 4.44 HVO_1759 ABC-type transport system permease protein (probable substrate iron-III) 6.74 1 2 2 2 4.140E5 137.67 6.74 2 2 371 38.8 8.91 HVO_1456 receiver/sensor box histidine kinase 6.72 1 1 2 3 7.432E6 257.93 6.72 2 3 506 53.8 4.70 HVO_0658 tRNA pseudouridine(13) synthase TruD 6.70 1 2 2 2 3.252E6 123.12 6.70 2 2 463 50.6 4.70 HVO_B0055 conserved hypothetical protein 6.67 1 2 2 4 6.407E6 1.95 6.67 2 2 177.81 6.67 2 2 225 23.9 4.69 HVO_0519 replication protein A 6.63 1 3 3 4 1.092E7 4.18 4.14 2 2 125.90 4.14 2 2 483 51.0 4.13 HVO_1491 HAD superfamily hydrolase 6.62 1 3 3 6 4.621E6 1.89 6.62 3 3 261.85 6.62 3 3 408 44.4 4.60 HVO_0304 electron transfer flavoprotein alpha subunit 6.62 1 2 2 9 1.062E7 801.27 6.62 2 9 317 33.5 4.18 HVO_0069 sulfatase 6.60 1 3 3 15 7.218E6 3.37 6.60 3 7 621.26 6.60 3 8 515 57.4 4.35 HVO_0798 dolichyl-phosphate mannosyltransferase AglD 6.57 1 3 4 19 2.000E7 19.21 5.93 3 9 1018.88 6.57 4 10 624 66.9 5.19 HVO_0215 iron-sulfur protein (4Fe-4S) 6.53 1 3 3 8 1.184E7 6.98 6.53 3 4 314.22 6.53 3 4 704 78.2 4.58 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 6.53 1 2 2 6 8.649E6 7.08 6.53 2 3 390.22 6.53 2 3 337 35.9 4.69 HVO_1374 acyl-CoA synthetase 6.51 1 3 3 16 3.038E7 21.17 6.51 3 8 1108.43 6.51 3 8 553 61.1 4.50 HVO_1940 DNA mismatch repair protein MutS 6.51 1 4 4 8 5.056E6 9.95 6.51 4 4 313.45 6.51 4 4 921 99.4 4.42 HVO_B0217 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 6.51 1 2 2 10 8.704E6 14.93 6.51 2 5 654.65 6.51 2 5 476 50.4 4.23 HVO_B0276 DMT superfamily transport protein 6.50 1 2 2 4 5.401E6 4.88 6.50 2 2 262.86 6.50 2 2 323 33.2 7.42 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 6.49 1 2 2 4 5.036E6 5.21 6.49 2 2 253.88 6.49 2 2 339 38.1 4.50 HVO_1725 Orc1-type DNA replication protein 6.48 1 2 2 3 3.063E6 9.58 6.48 2 3 401 44.5 5.19 HVO_1235 creatininase 6.44 1 2 2 8 1.226E7 3.77 6.44 2 4 288.42 6.44 2 4 264 29.2 4.84 HVO_1442 ABC-type transport system permease protein 6.42 1 4 4 10 7.448E6 9.31 6.42 4 5 586.50 6.42 4 5 623 63.2 5.34 HVO_0399 conserved hypothetical protein 6.36 1 2 2 3 4.535E6 5.74 6.36 2 3 346 36.0 3.95 HVO_2017 conserved hypothetical protein 6.32 1 2 2 4 3.292E6 2.08 6.32 2 2 138.78 6.32 2 2 459 48.2 4.98 HVO_2084 ABC-type transport system permease protein (probable substrate macrolides) 6.32 1 2 2 6 1.935E7 5.86 6.32 2 3 348.76 6.32 2 3 380 39.9 4.48 HVO_0229 conserved hypothetical protein 6.27 1 2 2 4 7.982E7 555.00 6.27 2 4 271 27.3 4.68 HVO_A0380 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 6.22 1 3 3 13 7.710E6 9.76 6.22 3 6 399.76 6.22 3 7 563 62.8 4.70 HVO_B0102 glycosidase family protein 6.20 1 2 2 2 4.014E6 177.07 6.20 2 2 355 38.7 4.75 HVO_1723 DNA repair helicase Rad25 6.19 1 3 3 4 4.394E6 231.48 6.19 3 4 695 76.8 4.69 HVO_1236 acyl-CoA synthetase 6.17 1 4 4 10 5.329E6 6.42 6.17 4 5 372.22 6.17 4 5 535 59.1 4.60 HVO_0733 transcription initiation factor TFB 6.13 1 0 2 8 4.107E7 9.78 6.13 2 4 607.58 6.13 2 4 326 37.2 6.00 18031720 keratin protein K6irs [Homo sapiens] 6.08 1 0 3 21 4.786E7 23.52 3.73 2 10 1242.76 6.08 3 11 510 55.7 6.89 28372503 keratin protein K6irs [Homo sapiens] 6.07 1 0 3 21 4.786E7 23.52 3.72 2 10 1242.76 6.07 3 11 511 55.8 6.89 HVO_2951 tryptophan--tRNA ligase 6.05 1 2 2 8 8.773E6 2.84 6.05 2 4 242.19 6.05 2 4 529 59.1 4.53 HVO_2120 conserved hypothetical protein 5.97 1 2 2 10 7.111E6 12.84 5.97 2 5 675.46 5.97 2 5 385 43.0 4.75 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 5.96 1 2 2 11 2.236E7 17.26 5.96 2 6 682.46 5.96 2 5 403 41.1 4.73 HVO_2190 gluconate permease 5.92 1 4 4 58 2.630E7 63.19 5.92 4 29 3464.52 5.92 4 29 473 49.0 4.96 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 5.86 1 2 2 6 9.227E6 8.13 5.86 2 3 371.12 5.86 2 3 512 53.8 4.78 HVO_0220 ATP-dependent DNA helicase MCM 5.84 1 2 2 4 2.449E6 5.12 5.84 2 2 123.48 5.84 2 2 702 78.8 4.73 HVO_2802 ABC-type transport system permease protein (probable substrate branched-chain amino acids) 5.84 1 3 3 12 1.534E7 14.49 5.84 3 6 562.12 5.84 3 6 445 47.4 8.51 4504919 keratin 8 [Homo sapiens] 5.80 1 0 3 14 6.283E7 7.10 5.80 3 7 767.06 5.80 3 7 483 53.7 5.59 HVO_3000 DNA ligase (NAD) 5.72 1 3 3 18 9.387E7 20.17 5.72 3 9 1112.49 5.72 3 9 699 75.8 4.50 HVO_A0570 probable metal-dependent hydrolase 5.58 1 2 2 6 8.129E6 3.77 5.58 2 3 255.62 5.58 2 3 466 50.4 4.56 109255249 keratin 4 [Homo sapiens] 5.56 1 0 4 16 5.463E7 12.75 5.56 4 8 932.80 5.56 4 8 594 63.9 8.25 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 5.52 1 3 3 7 5.639E6 7.35 5.52 3 3 338.77 5.52 3 4 634 66.1 4.54 HVO_B0037 ABC-type transport system ATP-binding protein (probable substrate sugar) 5.48 1 0 2 10 3.493E7 13.73 5.48 2 5 607.80 5.48 2 5 383 42.7 4.45 HVO_B0038 ABC-type transport system ATP-binding protein (probable substrate sugar) 5.48 1 0 2 10 3.493E7 13.73 5.48 2 5 607.80 5.48 2 5 383 41.6 4.53 HVO_B0316 ABC-type transport system ATP-binding protein (substrate glucose) 5.45 1 3 3 10 4.000E6 12.09 5.45 3 5 544.02 5.45 3 5 550 59.4 4.64 HVO_A0336 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 5.44 1 2 2 6 2.479E6 8.07 5.44 2 3 170.10 5.44 2 3 717 77.8 4.73 HVO_1683 4-alpha-glucanotransferase 5.44 1 3 3 6 6.410E6 3.89 5.44 3 3 333.82 5.44 3 3 496 56.3 4.45 HVO_1169 "probable glycosyltransferase, type 1" 5.43 1 2 2 6 2.232E6 4.04 5.43 2 3 252.90 5.43 2 3 368 40.8 4.73 HVO_1895 KEOPS complex subunit Kae1/Bud32 5.43 1 2 2 4 2.936E6 6.23 5.43 2 2 163.77 5.43 2 2 552 59.0 5.07 HVO_B0321 GFO family oxidoreductase 5.43 1 2 2 4 3.501E6 5.54 5.43 2 2 198.06 5.43 2 2 368 41.0 4.48 31074631 keratin 1b [Homo sapiens] 5.36 1 0 3 21 1.012E8 24.20 5.36 3 10 1453.86 5.36 3 11 578 61.8 5.97 HVO_A0127 tryptophan--tRNA ligase 5.34 1 2 2 2 1.852E8 5.31 5.34 2 2 393 44.2 5.12 4504911 keratin 13 isoform b [Homo sapiens] 5.24 1 0 3 12 1.690E7 14.70 5.24 3 6 496.08 5.24 3 6 420 45.8 4.88 HVO_2580 L-aspartate oxidase 5.21 1 2 2 6 4.227E6 7.49 5.21 2 3 327.95 5.21 2 3 537 55.8 4.63 HVO_B0309 aerobic-type carbon monoxide dehydrogenase large subunit 5.21 1 2 2 2 6.633E6 54.70 5.21 2 2 787 84.4 4.87 HVO_2803 ABC-type transport system permease protein (probable substrate branched-chain amino acids) 5.16 1 2 2 8 1.150E7 6.39 5.16 2 4 410.79 5.16 2 4 368 38.2 9.60 HVO_B0067 transport protein (probable substrate cationic amino acids) 5.16 1 2 2 4 6.910E6 4.40 5.16 2 2 206.06 5.16 2 2 465 48.3 5.01 HVO_2351 FxsA domain protein 5.15 1 2 2 10 2.647E7 1.81 5.15 2 5 383.23 5.15 2 5 194 20.1 5.29 HVO_0741 DNA-directed DNA polymerase X 5.15 1 2 2 2 4.029E6 88.34 5.15 2 2 582 62.6 4.44 HVO_2124 ABC-type transport system permease protein (probable substrate dipeptide/oligopeptide) 5.09 1 2 2 8 2.302E7 8.29 5.09 2 4 315.71 5.09 2 4 334 35.8 5.01 HVO_2055 probable transport protein (probable polysaccharide biosynthesis transport protein) 5.08 1 2 2 8 8.174E6 10.44 5.08 2 4 325.37 5.08 2 4 472 51.1 9.11 HVO_A0553 adenosylcobyric acid synthase 5.08 1 2 2 4 0.000E0 3.97 5.08 2 2 103.95 5.08 2 2 512 52.6 4.50 HVO_2732 FixC family protein 5.05 1 2 2 6 4.184E6 4.36 5.05 2 3 257.59 5.05 2 3 554 59.8 4.83 HVO_1914 acetyl-CoA C-acyltransferase 5.04 1 2 2 4 3.831E6 282.90 5.04 2 4 377 39.9 4.41 HVO_0662 HTH domain protein / thiamine-phosphate synthase 5.02 1 2 2 10 1.685E7 6.02 5.02 2 5 397.06 5.02 2 5 299 31.9 4.44 HVO_2670 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 4.91 1 5 5 16 9.259E6 2.01 4.91 5 8 629.76 4.91 5 8 1058 113.8 4.69 HVO_B0324 conserved hypothetical protein 4.90 1 2 2 4 1.091E7 1.91 4.90 2 2 147.33 4.90 2 2 449 48.0 4.58 HVO_1113 "FtsZ family protein, type III" 4.88 1 1 2 4 2.148E8 282.02 4.88 2 4 389 40.8 4.89 HVO_0648 DUF2070 family protein 4.87 1 2 2 7 7.347E6 3.83 4.87 2 2 193.62 4.87 2 5 637 67.7 4.77 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 4.80 1 0 3 12 1.690E7 14.70 4.80 3 6 496.08 4.80 3 6 458 49.6 4.96 HVO_1920 transport protein (probable substrate dicarboxylate) 4.79 1 2 2 8 5.593E7 8.14 4.79 2 4 435.54 4.79 2 4 522 55.0 4.74 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 4.78 1 2 2 6 6.068E6 5.08 4.78 2 3 323.24 4.78 2 3 439 47.2 4.59 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 4.77 1 2 2 8 5.894E6 3.35 4.77 2 4 307.44 4.77 2 4 482 50.6 4.31 HVO_2482 HD family hydrolase 4.68 1 0 2 8 6.513E6 7.47 4.68 2 4 446.12 4.68 2 4 406 44.7 4.89 HVO_0415 repair helicase 4.55 1 2 2 8 1.624E7 10.03 4.55 2 4 372.06 4.55 2 4 616 69.6 4.70 HVO_2575 homolog to translation elongation factor aEF-1 alpha subunit 4.49 1 2 2 7 4.770E6 9.28 4.49 2 4 260.26 4.49 2 3 534 57.8 4.81 HVO_1066 Mrp-type sodium/proton antiporter system subunit D1 4.42 1 2 2 8 1.153E7 8.88 4.42 2 4 333.28 4.42 2 4 565 58.1 5.25 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 4.27 1 3 3 8 3.898E6 2.00 2.25 2 3 298.00 4.27 3 5 1335 150.5 4.60 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 4.26 1 2 2 4 4.166E6 0.00 4.26 2 2 128.07 4.26 2 2 658 72.1 4.70 HVO_0029 UvrABC system protein B 4.15 1 3 3 7 3.911E6 4.17 4.15 3 3 409.53 4.15 3 4 698 79.0 4.45 HVO_B0052 PQQ repeat protein 4.13 1 2 2 2 1.331E6 163.46 4.13 2 2 412 44.1 5.48 HVO_2249 xanthine/uracil permease family transport protein 3.90 1 2 2 6 3.558E6 1.61 3.90 2 3 158.28 3.90 2 3 462 46.8 4.34 HVO_2955 DEAD/DEAH box helicase 3.85 1 2 2 4 2.216E6 0.00 3.85 2 2 132.11 3.85 2 2 779 85.8 4.94 HVO_1927 DUF389 family protein 3.69 1 2 2 4 2.642E6 2.10 3.69 2 2 120.77 3.69 2 2 434 45.6 4.60 15618995 keratin 6 irs [Homo sapiens] 3.63 1 0 2 20 6.857E7 23.52 3.63 2 10 1162.07 3.63 2 10 523 57.3 6.61 28173552 keratin 6 irs4 [Homo sapiens] 3.59 1 0 2 20 6.857E7 23.52 3.59 2 10 1162.07 3.59 2 10 529 57.8 7.71 31074633 keratin 6L [Homo sapiens] 3.55 1 0 2 8 9.882E7 5.92 3.55 2 4 600.94 3.55 2 4 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 3.55 1 0 2 8 9.882E7 5.92 3.55 2 4 600.94 3.55 2 4 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 3.55 1 0 2 8 9.882E7 5.92 3.55 2 4 600.94 3.55 2 4 535 57.7 7.20 28173564 keratin 6 irs3 [Homo sapiens] 3.52 1 0 2 20 6.857E7 23.52 3.52 2 10 1162.07 3.52 2 10 540 58.9 7.23 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 14 1.101E8 3.73 3.45 2 7 609.95 3.45 2 7 464 50.6 5.47 66774007 "Keratin, type II cytoskeletal 1b" 3.30 1 0 2 10 4.562E7 8.82 3.30 2 5 593.09 3.30 2 5 576 61.7 5.85 HVO_0633 KaiC-type circadian regulator Circ3 3.10 1 1 2 3 4.038E6 293.33 3.10 2 3 484 52.7 5.06 HVO_2766 ATP-dependent DNA helicase 2.51 1 2 2 2 3.618E6 4.70 2.51 2 2 918 102.7 5.07 HVO_2767 ATP-dependent DNA helicase Dna2 2.26 1 1 2 5 9.726E6 2.12 2.26 2 3 114.96 2.26 2 2 884 97.5 4.86 HVO_1656 YyaL family protein 2.13 1 2 2 6 5.014E6 1.80 2.13 2 3 188.99 2.13 2 3 703 77.3 4.49 HVO_B0265 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 1.81 1 1 2 3 6.190E7 0.00 1.81 2 3 1048 112.5 4.61 HVO_2827 UvrD/REP family helicase 1.70 1 2 2 2 1.709E6 2.36 1.70 2 2 1174 129.9 4.79 HVO_A0088 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 1.56 1 1 2 4 7.670E5 0.00 1.56 2 2 120.14 1.56 2 2 1024 111.3 4.69