Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0359 translation elongation factor aEF-1 alpha subunit 79.57 1 20 24 1234 7.884E10 1141.77 79.57 23 571 91651.57 79.57 24 663 421 45.7 4.73 HVO_0880 conserved hypothetical protein 76.87 1 27 27 259 3.806E9 262.83 76.87 27 130 17295.56 76.87 27 129 307 36.3 4.74 HVO_0356 translation elongation factor aEF-2 74.97 1 44 44 925 2.760E10 784.58 74.00 42 455 51048.88 68.91 42 470 727 80.4 4.73 HVO_2783 30S ribosomal protein S4 69.14 1 12 12 94 5.583E9 68.00 69.14 11 46 5646.51 69.14 12 48 175 20.1 5.24 HVO_2862 serine hydroxymethyltransferase 67.23 1 17 17 236 8.276E9 186.68 65.30 16 116 13718.17 67.23 17 120 415 44.3 4.53 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 64.57 1 17 17 327 1.495E10 266.09 64.57 17 165 19538.71 64.57 17 162 350 37.6 4.54 HVO_1921 serine--tRNA ligase 64.57 1 23 23 116 2.170E9 106.66 60.43 22 57 7325.63 64.57 23 59 460 52.0 4.46 HVO_0433 F420H2:NADP oxidoreductase 64.41 1 8 8 37 1.612E9 41.02 47.30 7 18 2296.44 64.41 8 19 222 23.3 4.72 HVO_0677 aspartate--tRNA ligase 63.36 1 19 19 263 8.963E9 186.36 63.36 19 132 13628.53 63.36 19 131 434 48.7 4.50 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 62.18 1 12 12 264 9.340E9 196.76 62.18 12 138 13108.35 62.18 12 126 312 34.5 4.98 HVO_0025 thiosulfate sulfurtransferase 61.89 1 11 11 315 1.732E10 279.62 59.44 10 161 16250.48 61.89 11 154 286 32.1 4.28 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 61.58 1 7 7 44 2.499E9 27.78 61.58 7 22 2459.09 47.89 6 22 190 20.6 4.30 HVO_1145 30S ribosomal protein S1e 60.91 1 13 13 83 2.931E9 77.75 60.91 13 41 5633.85 60.91 13 42 220 24.8 4.86 HVO_0175 DNA polymerase sliding clamp 60.73 1 10 10 151 5.396E9 114.67 60.73 10 75 8142.43 59.11 9 76 247 26.7 4.39 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 60.50 1 13 13 73 2.277E9 69.03 60.50 13 38 4202.94 54.80 11 35 281 30.6 4.59 HVO_2900 fumarate hydratase 59.70 1 17 17 162 7.363E9 163.32 59.70 16 82 9911.71 52.03 16 80 469 50.1 4.78 HVO_1637 FKBP-type peptidylprolyl isomerase 59.48 1 11 12 95 5.756E9 66.45 50.98 11 45 5292.54 59.48 12 50 306 33.8 3.76 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 59.32 1 15 15 156 1.117E10 126.42 59.32 15 78 9595.57 59.32 15 78 381 41.0 4.23 HVO_0055 CBS domain protein 59.15 1 11 11 74 3.683E9 73.80 59.15 11 36 5076.58 59.15 11 38 284 30.8 4.27 HVO_2724 beta-lactamase domain protein 59.11 1 19 19 202 5.649E9 163.52 59.11 19 102 11296.49 57.78 18 100 450 50.1 5.40 HVO_0850 proteasome-activating nucleotidase 58.27 1 16 17 80 1.722E9 48.00 49.14 14 37 3858.55 58.27 17 43 405 45.6 4.60 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 57.35 1 14 14 55 6.532E8 33.36 57.35 14 27 2340.38 57.35 14 28 422 43.6 4.72 HVO_0581 "cell division protein FtsZ, type II" 57.25 1 14 14 86 2.589E9 85.96 57.25 14 44 5319.44 50.00 13 42 400 42.5 4.75 HVO_0329 branched-chain amino acid aminotransferase 56.09 1 15 15 102 4.029E9 106.43 48.08 14 52 6533.49 54.17 14 50 312 35.0 4.58 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 55.28 1 13 13 43 1.053E9 36.24 55.28 13 23 2241.39 45.62 11 20 445 47.8 4.86 HVO_0869 glutamate synthase large subunit 54.93 1 60 61 371 4.336E9 326.52 51.95 57 185 22974.75 53.87 60 186 1511 163.8 4.70 HVO_2544 30S ribosomal protein S5 54.67 1 11 11 95 1.056E10 72.31 54.67 11 49 4832.53 52.34 10 46 214 23.3 9.29 HVO_2969 threonine synthase 53.94 1 16 16 98 3.694E9 69.50 52.27 15 48 5422.00 51.31 15 50 419 44.4 4.49 HVO_0347 DNA-directed RNA polymerase subunit B'' 53.93 1 25 25 149 2.526E9 110.37 49.71 22 73 7649.59 52.59 24 76 521 58.9 5.00 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 53.91 1 15 15 137 6.686E9 161.40 53.91 15 70 10472.17 53.91 15 67 384 41.4 4.41 HVO_0317 A-type ATP synthase subunit B 53.85 1 15 16 138 9.080E9 131.15 53.85 16 69 9785.52 53.85 16 69 468 51.9 4.25 HVO_0859 FeS assembly ATPase SufC 53.49 1 13 13 122 5.027E9 90.12 51.50 12 58 7203.73 53.49 13 64 301 33.4 4.35 HVO_2968 phosphoglycerate dehydrogenase 53.14 1 20 20 204 8.581E9 211.86 53.14 20 101 13801.01 53.14 20 103 525 55.3 4.36 HVO_2588 isocitrate dehydrogenase (NADP) 52.74 1 19 19 177 1.171E10 199.09 49.64 17 89 12257.53 51.07 18 88 419 45.8 4.59 HVO_2413 translation elongation factor aEF-1 alpha subunit 52.62 1 12 16 122 1.227E10 87.06 48.33 15 60 7137.84 43.57 14 62 420 45.6 4.75 HVO_0980 NADH dehydrogenase-like complex subunit CD 52.24 1 15 19 64 1.388E9 37.69 42.19 17 31 2852.06 47.40 18 33 557 63.4 4.53 HVO_1973 conserved hypothetical protein 52.10 1 5 5 19 1.925E8 14.73 43.11 4 9 1101.29 52.10 5 10 167 18.1 4.36 HVO_1273 inosine-5'-monophosphate dehydrogenase 52.01 1 16 16 168 4.105E9 142.21 49.40 15 83 9782.97 52.01 16 85 498 53.3 4.55 HVO_0778 thermosome subunit 3 51.72 1 19 21 137 2.191E9 146.31 48.66 19 67 9629.30 51.72 21 70 524 55.2 4.59 HVO_0239 glutamine synthetase 51.54 1 17 18 139 7.919E9 94.10 50.44 16 69 7855.97 51.54 18 70 456 50.5 4.56 HVO_1502 3-isopropylmalate dehydrogenase 50.93 1 13 13 82 3.608E9 81.72 37.96 11 38 5714.05 50.93 13 44 324 33.7 4.23 HVO_1132 adenylosuccinate synthase 50.56 1 21 21 276 8.431E9 203.00 47.40 20 135 14822.35 50.56 20 141 443 48.2 4.56 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 32 1.711E9 14.62 37.91 4 15 1277.01 50.33 5 17 153 16.9 4.21 HVO_3007 malate dehydrogenase 50.33 1 11 11 230 8.887E9 234.61 50.33 11 114 12747.39 36.51 10 116 304 32.6 4.40 HVO_0860 SufB domain protein 50.21 1 18 18 169 5.585E9 152.11 47.06 17 83 10153.70 50.21 18 86 476 53.2 4.69 HVO_2552 30S ribosomal protein S4e 50.20 1 9 9 156 2.034E10 131.20 47.37 8 76 8353.25 50.20 9 80 247 26.6 4.58 HVO_2384 CBS domain protein 50.00 1 18 18 101 4.882E9 73.10 47.63 17 50 5083.41 48.68 16 51 380 42.5 5.01 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 49.65 1 9 9 46 1.351E9 38.46 47.20 8 23 2593.91 49.65 9 23 286 31.2 4.54 HVO_0314 A-type ATP synthase subunit C 49.43 1 14 14 71 1.643E9 67.56 45.40 13 36 4588.82 45.98 13 35 348 38.7 4.50 HVO_2889 RecJ domain protein 49.25 1 26 26 228 7.845E9 204.24 49.25 26 112 14330.03 48.29 25 116 729 79.1 4.37 HVO_1541 glycerol kinase 49.22 1 20 20 137 6.309E9 107.06 44.90 18 68 9196.24 47.65 19 69 510 56.7 4.50 HVO_A0207 CRISPR-associated protein Cas7 49.12 1 9 9 50 9.907E8 49.55 49.12 9 25 3203.23 49.12 9 25 340 38.2 4.54 HVO_0348 DNA-directed RNA polymerase subunit B' 49.10 1 23 23 162 2.229E9 133.40 49.10 23 81 8945.87 47.29 22 81 609 67.7 4.92 HVO_0789 tryptophan synthase alpha subunit 48.74 1 8 8 30 5.077E8 23.96 48.74 8 15 1482.79 48.74 8 15 277 29.6 4.21 HVO_0861 SufB domain protein 48.26 1 14 14 108 4.547E9 99.98 48.26 14 56 7521.31 48.26 14 52 402 44.7 4.23 HVO_1454 aspartate carbamoyltransferase catalytic subunit 47.70 1 9 9 34 4.692E8 25.17 47.70 9 17 1714.43 47.70 9 17 304 33.7 4.92 HVO_2558 30S ribosomal protein S3 47.70 1 13 13 183 7.146E9 177.56 43.42 12 89 13000.13 47.70 13 94 304 33.4 4.06 HVO_0400 conserved hypothetical protein 47.62 1 3 3 12 1.055E8 9.99 47.62 3 6 377.56 47.62 3 6 126 13.9 4.68 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 47.21 1 13 13 78 3.326E9 58.15 40.98 11 35 4972.46 47.21 13 43 305 33.8 4.74 HVO_1506 ketol-acid reductoisomerase 47.13 1 11 11 48 7.457E8 52.12 45.11 10 22 3281.94 47.13 11 26 348 37.9 4.34 HVO_2519 conserved hypothetical protein 47.12 1 13 13 54 1.294E9 34.68 41.10 11 23 3575.06 47.12 13 31 382 40.7 4.35 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 47.04 1 10 10 50 2.149E9 41.99 47.04 10 25 2903.93 47.04 10 25 355 38.2 4.68 HVO_0133 thermosome subunit 1 46.96 1 18 20 139 3.804E9 129.93 46.96 20 70 9330.94 44.64 18 69 560 58.9 4.25 HVO_2204 "FtsZ family protein, type III" 46.84 1 14 17 82 3.279E9 76.68 45.32 16 41 5313.80 45.06 16 41 395 42.0 4.68 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 46.43 1 21 21 366 2.007E10 379.77 45.17 20 181 26296.18 46.43 21 185 631 68.4 4.49 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 135 3.799E9 135.13 43.25 7 65 9044.87 46.37 8 70 289 29.8 4.27 HVO_1080 conserved hypothetical protein 46.28 1 6 6 28 5.505E8 20.61 46.28 6 14 1259.62 42.02 5 14 188 21.1 4.31 HVO_2191 formyltetrahydrofolate deformylase 45.87 1 12 12 68 3.014E9 61.52 45.87 12 35 4217.02 45.87 12 33 327 36.2 4.63 HVO_0024 thiosulfate sulfurtransferase 45.74 1 8 8 30 1.241E9 27.29 41.09 7 13 2017.91 45.74 8 17 258 28.4 4.30 HVO_1300 triosephosphate isomerase 45.33 1 6 6 42 4.832E9 42.73 45.33 6 21 3153.66 45.33 6 21 214 21.3 4.26 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 45.30 1 9 9 104 3.350E9 106.42 45.30 9 53 6792.47 43.21 8 51 287 31.0 4.73 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 45.27 1 19 19 138 4.942E9 116.12 44.26 18 67 7772.49 45.27 19 71 592 66.6 4.61 HVO_0455 thermosome subunit 2 45.24 1 20 21 172 4.097E9 115.05 45.24 21 81 9685.49 45.24 20 91 557 59.3 4.37 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 45.21 1 6 6 29 1.436E9 21.84 39.36 5 14 1668.34 45.21 6 15 188 20.5 4.60 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 45.00 1 10 10 55 3.346E9 33.36 37.14 9 27 2644.03 45.00 10 28 280 30.1 4.44 HVO_2549 30S ribosomal protein S8 44.62 1 6 6 28 1.586E9 22.38 44.62 6 14 1255.56 44.62 5 14 130 14.1 4.79 HVO_1955 aconitate hydratase 44.50 1 23 23 309 9.753E9 309.07 43.73 22 151 20773.98 44.50 23 158 654 70.4 4.45 HVO_A0206 CRISPR-associated protein Cas8b 44.07 1 24 24 100 1.408E9 71.74 41.42 22 51 4813.19 36.54 20 49 717 79.3 4.60 HVO_1082 homolog to orotate phosphoribosyltransferase 43.81 1 7 7 28 1.310E9 17.73 43.81 7 14 1662.66 40.00 6 14 210 22.3 4.42 HVO_2015 conserved hypothetical protein 43.48 1 9 9 185 1.793E10 189.51 43.48 9 91 13099.23 43.48 9 94 345 37.7 4.25 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 43.00 1 19 19 229 5.144E9 197.41 41.98 18 115 12469.17 43.00 19 114 586 64.0 4.49 HVO_1284 GTP cyclohydrolase III 42.91 1 7 7 27 2.934E8 24.98 32.95 6 13 1622.89 42.91 7 14 261 28.9 4.70 HVO_0358 homoserine dehydrogenase 42.90 1 7 8 34 1.191E9 33.56 42.90 8 18 1704.43 42.90 8 16 317 32.4 4.44 HVO_2913 superoxide dismutase (Mn) 42.71 1 0 4 36 6.743E9 47.46 42.71 4 19 2721.24 29.65 3 17 199 22.3 4.48 HVO_0999 DRTGG domain protein 42.59 1 11 11 67 1.513E9 55.27 42.59 11 33 3429.96 42.59 11 34 378 39.8 4.44 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 42.57 1 7 7 29 4.978E8 22.35 42.57 7 15 1637.04 38.12 6 14 202 22.2 5.11 HVO_A0475 superoxide dismutase (Mn) 42.50 1 0 4 36 6.743E9 47.46 42.50 4 19 2721.24 29.50 3 17 200 22.4 4.45 HVO_2621 phosphoenolpyruvate carboxylase 42.47 1 30 30 199 3.952E9 137.16 41.81 29 100 10808.14 42.47 30 99 897 102.3 4.64 HVO_2646 dihydroxy-acid dehydratase 42.47 1 16 16 114 2.591E9 100.43 42.47 15 56 6422.97 42.47 16 58 584 61.8 4.42 HVO_2487 aspartate-semialdehyde dehydrogenase 42.44 1 9 9 83 4.137E9 54.17 42.44 9 43 3184.79 42.15 8 40 344 36.6 4.41 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.11 1 9 9 48 1.277E9 41.73 42.11 9 24 2603.08 42.11 9 24 266 27.8 4.84 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 42.10 1 15 15 100 2.600E9 87.62 40.19 14 47 6008.72 42.10 15 53 525 56.4 4.40 HVO_0167 adenosylhomocysteinase 41.59 1 10 10 39 8.897E8 21.89 32.01 8 18 2169.92 41.59 10 21 428 46.6 4.39 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 41.58 1 12 12 53 1.478E9 42.91 41.58 12 26 2741.31 41.58 12 27 457 48.4 4.35 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 41.53 1 15 15 70 1.568E9 48.52 41.53 15 35 3599.73 41.53 15 35 496 55.0 4.53 HVO_0240 Lrp/AsnC family transcription regulator 41.45 1 5 6 32 1.963E9 22.72 41.45 6 16 1852.44 41.45 6 16 152 16.9 4.39 HVO_0046 putative glutamate--argW ligase 40.89 1 9 9 41 1.182E9 40.61 40.89 9 20 2801.69 40.89 9 21 291 31.9 4.87 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 40.73 1 16 16 56 1.236E9 31.03 40.73 16 28 2608.62 38.82 15 28 626 67.6 4.65 HVO_2861 conserved hypothetical protein 40.73 1 9 9 47 1.298E9 39.48 32.00 8 23 2472.24 40.73 9 24 275 29.1 4.27 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 40.68 1 9 9 58 4.235E9 36.07 40.68 9 29 3228.35 40.68 9 29 413 45.8 4.45 HVO_0480 phosphoglycerate kinase 40.65 1 14 14 65 2.719E9 62.23 40.65 14 32 4279.90 40.65 14 33 401 43.6 4.37 HVO_0316 A-type ATP synthase subunit A 40.27 1 17 17 147 6.864E9 148.45 40.27 17 75 9395.89 40.27 17 72 586 64.5 4.25 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 70 2.186E9 66.07 40.26 5 38 4812.34 40.26 5 32 154 17.5 4.50 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 40.18 1 8 8 67 5.973E8 55.89 40.18 8 32 3760.33 40.18 8 35 336 36.8 4.12 HVO_0104 DNA repair and recombination protein RadA 39.94 1 11 11 77 3.083E9 66.93 34.69 10 37 5687.91 39.94 11 40 343 37.3 4.64 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 39.87 1 14 14 47 1.352E9 40.18 39.87 13 23 2382.08 37.55 12 24 474 53.4 4.59 HVO_1212 KaiC-type circadian regulator CirA 39.84 1 9 9 46 2.182E9 60.65 37.80 8 23 3859.25 37.40 8 23 246 27.5 4.45 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 39.44 1 9 9 66 2.119E9 38.06 39.44 9 32 3001.71 39.44 9 34 360 39.6 4.39 HVO_1198 UspA domain protein 39.31 1 5 5 21 1.512E9 21.35 39.31 5 11 1242.26 39.31 5 10 145 15.6 4.75 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 39.18 1 4 4 42 1.472E9 26.39 28.35 3 16 3051.14 39.18 4 26 194 20.7 4.12 HVO_0161 ATP phosphoribosyltransferase 39.15 1 8 8 40 8.604E8 39.64 39.15 8 20 2844.47 39.15 8 20 281 30.4 4.60 HVO_2419 hydroxymethylglutaryl-CoA synthase 39.10 1 13 13 64 2.027E9 43.08 36.40 12 31 3305.74 39.10 13 33 445 50.1 4.64 HVO_A0205 CRISPR-associated endoribonuclease Cas6 38.97 1 10 10 47 4.486E8 38.23 38.97 10 24 2550.19 35.66 9 23 272 31.0 5.44 HVO_0870 proline--tRNA ligase 38.93 1 12 12 67 2.445E9 52.69 36.48 11 33 3807.14 37.70 11 34 488 54.9 4.44 HVO_0809 methionine--tRNA ligase 38.78 1 19 19 101 1.366E9 67.81 38.78 19 51 4879.83 38.78 19 50 740 81.9 4.37 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 38.72 1 7 7 50 2.279E9 50.30 38.72 7 26 2644.14 38.72 7 24 297 31.3 4.36 HVO_1858 30S ribosomal protein S19e 38.41 1 3 3 9 4.543E7 0.00 26.49 2 4 321.49 38.41 3 5 151 16.7 4.84 HVO_2188 phosphoribosylformylglycinamidine synthase 1 38.39 1 6 6 21 6.774E8 17.71 38.39 6 10 1053.51 38.39 6 11 224 23.9 4.36 HVO_2774 enolase 38.35 1 10 10 68 4.294E9 59.29 38.35 10 34 4075.75 38.35 10 34 399 42.0 4.37 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 38.24 1 10 10 35 5.061E8 24.99 38.24 10 18 1799.39 31.76 9 17 340 38.8 4.58 HVO_1507 acetolactate synthase small subunit 38.07 1 6 6 23 4.881E8 16.86 38.07 6 11 1076.02 38.07 6 12 218 23.7 4.94 HVO_2624 CTP synthase 38.07 1 13 13 67 2.758E9 41.69 38.07 13 34 3455.94 38.07 13 33 549 60.8 4.70 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 64 1.783E9 78.19 33.87 7 30 4809.98 38.05 9 34 431 46.1 4.48 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 38.04 1 15 16 71 1.090E9 69.55 34.03 14 32 4031.98 38.04 16 39 623 62.1 5.30 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.95 1 11 11 73 2.465E9 43.26 37.95 11 37 3088.04 37.95 11 36 332 34.8 4.22 HVO_1593 PAC2 family protein 37.90 1 5 5 20 4.658E8 9.81 37.90 5 10 666.54 37.90 5 10 248 26.6 4.46 HVO_0729 inorganic pyrophosphatase 37.85 1 7 7 52 2.558E9 46.00 37.85 7 26 3219.55 37.85 7 26 177 20.4 4.16 HVO_2555 30S ribosomal protein S17 37.72 1 2 2 8 2.707E8 2.13 37.72 2 4 180.87 37.72 2 4 114 12.7 4.81 HVO_1684 threonine--tRNA ligase 37.64 1 22 22 129 2.802E9 96.97 37.64 22 66 7156.07 37.64 22 63 643 73.4 4.45 HVO_1504 3-isopropylmalate dehydratase large subunit 37.63 1 14 15 124 4.498E9 113.34 37.42 14 61 8014.83 37.63 15 63 473 51.6 4.55 HVO_0203 replication factor C small subunit 37.61 1 9 9 37 8.202E8 24.52 37.61 9 20 1670.82 37.61 9 17 327 36.2 4.51 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 37.61 1 10 10 45 1.073E9 37.72 37.61 10 23 2728.79 37.61 10 22 343 38.4 4.94 HVO_0401 UspA domain protein 37.50 1 5 5 25 7.034E8 28.11 32.89 4 12 1417.17 37.50 5 13 152 16.4 4.79 HVO_1901 translation initiation factor aIF-2 gamma subunit 37.47 1 11 11 83 2.934E9 40.20 37.47 11 41 3760.16 37.47 11 42 411 43.9 4.36 HVO_0511 NAD-dependent epimerase/dehydratase 37.40 1 6 6 30 4.052E8 21.30 27.10 5 14 1733.64 37.40 6 16 262 29.3 4.78 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 37.15 1 5 5 13 6.140E8 8.11 10.28 2 5 606.45 37.15 5 8 253 26.0 4.60 HVO_2347 conserved hypothetical protein 37.14 1 4 4 18 2.321E8 20.79 37.14 4 9 1291.40 37.14 4 9 140 15.5 4.37 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 37.00 1 17 17 76 9.677E8 74.51 33.00 15 37 5033.38 36.00 16 39 600 65.3 4.68 HVO_1091 proteasome alpha subunit 36.90 1 8 9 57 2.560E9 54.33 36.90 9 28 3722.01 36.90 9 29 252 27.6 4.56 HVO_0806 pyruvate kinase 36.58 1 14 14 103 3.499E9 86.89 36.58 14 50 6254.82 36.58 14 53 585 62.0 4.54 HVO_0788 tryptophan synthase beta subunit 36.26 1 10 10 36 8.397E8 26.71 28.91 9 17 1897.32 36.26 10 19 422 45.7 4.65 HVO_2773 30S ribosomal protein S2 36.15 1 5 5 73 7.308E9 85.51 36.15 5 35 5729.17 36.15 5 38 260 28.3 4.16 HVO_0138 tyrosine--tRNA ligase 35.98 1 8 8 40 9.911E8 21.26 25.00 6 18 1914.62 35.98 8 22 328 36.1 4.34 HVO_0353 30S ribosomal protein S12 35.92 1 8 8 36 1.337E9 37.65 35.92 8 20 1821.57 32.39 7 16 142 15.5 9.91 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 35.84 1 8 8 34 8.013E8 26.30 35.84 8 17 1996.78 35.84 8 17 226 25.5 4.25 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 35.82 1 32 32 185 1.826E9 137.00 34.37 30 88 10385.50 35.82 32 97 1033 114.3 4.45 HVO_2813 RimK family protein 35.54 1 13 13 76 1.574E9 70.31 32.23 11 37 4677.94 35.54 13 39 453 49.0 4.73 HVO_0424 ABC-type transport system ATP-binding protein 35.43 1 15 15 55 5.297E8 45.65 34.11 14 28 2970.69 33.94 14 27 604 67.2 4.49 HVO_0743 probable phosphodiesterase 35.41 1 16 16 86 1.895E9 50.64 35.41 16 43 4108.65 35.41 16 43 449 50.5 4.56 HVO_1459 ThuA family protein 35.29 1 4 4 23 9.081E8 23.58 22.69 3 11 1549.15 35.29 4 12 238 26.8 4.67 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 35.04 1 5 5 28 3.981E8 18.90 15.75 3 13 1312.31 35.04 5 15 254 26.9 4.42 HVO_1481 UspA domain protein 34.97 1 4 4 46 3.284E9 42.23 34.97 4 23 3004.64 34.97 4 23 163 17.7 4.40 HVO_0350 DNA-directed RNA polymerase subunit A'' 34.61 1 13 13 61 3.279E9 51.26 34.61 13 29 3832.19 33.41 12 32 419 46.1 4.35 HVO_2057 sugar nucleotidyltransferase 34.45 1 10 10 43 1.758E9 38.71 34.45 9 22 2350.23 34.45 10 21 357 37.8 4.44 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 34.39 1 3 4 14 2.090E8 5.49 9.52 2 6 498.02 34.39 4 8 189 21.7 4.46 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 34.36 1 11 11 66 1.734E9 35.70 30.12 8 28 3792.16 34.36 11 38 259 29.9 4.36 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 34.34 1 9 9 35 3.892E8 18.12 34.34 9 18 1678.75 34.34 9 17 364 39.3 4.35 HVO_0449 prephenate dehydratase 34.33 1 7 7 45 5.741E8 41.33 34.33 7 22 2755.85 34.33 7 23 268 28.7 4.64 HVO_2059 NAD-dependent epimerase/dehydratase 34.19 1 7 7 45 9.096E8 29.39 34.19 7 23 2027.51 30.65 6 22 310 34.1 4.40 HVO_1545 dihydroxyacetone kinase subunit DhaL 34.05 1 7 7 67 2.482E9 54.48 34.05 7 34 3442.44 34.05 7 33 232 24.8 4.48 HVO_1306 chorismate synthase 34.03 1 9 9 50 2.957E8 45.42 34.03 9 26 2123.35 30.65 8 24 385 41.9 4.83 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 33.98 1 6 6 49 1.753E9 40.77 33.98 6 25 2851.25 33.98 6 24 259 28.0 4.50 HVO_0519 replication protein A 33.95 1 14 14 63 6.963E8 38.71 31.06 13 32 2878.14 31.68 13 31 483 51.0 4.13 HVO_1031 thioredoxin-disulfide reductase 33.92 1 7 7 32 7.331E8 26.83 33.92 7 15 1488.57 33.92 7 17 342 37.4 4.46 HVO_0324 arginine--tRNA ligase 33.90 1 17 17 73 1.846E9 67.26 33.90 17 37 4111.86 33.90 17 36 587 65.0 4.35 HVO_0049 argininosuccinate synthase 33.83 1 11 11 53 3.763E9 42.07 33.83 11 27 2808.23 33.83 11 26 405 44.5 4.34 HVO_0717 "cell division protein FtsZ, type I" 33.77 1 11 11 66 5.389E9 54.20 33.77 11 33 3886.95 30.87 10 33 379 39.8 4.40 HVO_1018 RecJ domain protein 33.65 1 17 17 84 1.165E9 65.13 29.23 15 40 4811.25 33.65 17 44 633 69.8 4.58 HVO_B0118 SMC-like protein Sph2 33.54 1 20 20 112 2.051E9 99.65 32.76 19 55 6325.02 32.76 19 57 644 73.8 4.41 HVO_0313 A-type ATP synthase subunit E 33.51 1 4 4 29 7.192E8 27.70 26.29 3 13 2070.75 33.51 4 16 194 22.0 4.31 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 33.49 1 15 15 76 1.929E9 65.70 33.49 15 38 4214.39 32.69 14 38 624 67.6 4.27 HVO_2726 glutamate--tRNA ligase 33.33 1 13 13 66 1.260E9 41.22 28.72 12 33 3062.56 33.33 13 33 585 65.2 4.58 HVO_0484 50S ribosomal protein L10e 32.95 1 5 5 19 1.198E8 14.11 32.95 5 10 1007.20 27.27 4 9 176 19.8 8.72 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 32.70 1 12 12 56 1.200E9 38.82 27.81 11 28 2783.08 32.70 12 28 471 51.0 4.48 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 32.61 1 5 5 11 1.960E8 6.09 27.17 4 6 440.66 32.61 5 5 184 19.8 5.30 HVO_0292 replication protein A 32.48 1 8 8 25 4.235E8 17.81 27.33 7 12 1482.09 29.90 7 13 311 34.6 4.31 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 32.23 1 9 9 33 2.731E8 24.34 32.23 9 18 1618.96 29.75 8 15 363 39.3 4.97 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 32.13 1 9 9 19 1.350E8 6.66 32.13 9 11 840.29 18.92 6 8 333 36.7 4.56 HVO_0863 SirR/DtxR family transcription regulator 32.00 1 2 2 2 2.044E7 24.16 32.00 2 2 150 16.6 4.18 HVO_2013 "FtsZ family protein, type III" 31.98 1 5 5 30 2.891E8 42.30 31.98 5 15 2728.80 31.98 5 15 394 41.5 4.61 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 31.89 1 13 13 48 6.007E8 49.48 30.55 12 24 3145.83 30.22 12 24 599 65.3 4.51 HVO_2981 uracil phosphoribosyltransferase 31.86 1 4 4 24 1.225E9 16.93 24.34 3 10 1183.82 31.86 4 14 226 24.5 4.49 HVO_1572 DNA gyrase subunit B 31.46 1 14 14 48 4.684E8 33.36 31.46 14 23 2302.60 30.52 13 25 639 71.2 4.83 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 34 5.600E9 35.79 31.45 3 17 2797.09 31.45 3 17 124 14.2 5.22 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 31.34 1 3 3 12 2.918E8 8.01 24.63 2 4 1031.20 31.34 3 8 134 13.9 4.55 HVO_0415 repair helicase 31.33 1 16 16 58 1.370E9 42.16 29.87 14 29 3255.71 30.36 15 29 616 69.6 4.70 HVO_2417 conserved hypothetical protein 31.28 1 4 4 16 7.228E8 8.74 31.28 4 9 442.53 23.59 3 7 195 21.6 3.65 HVO_1590 DnaK-type molecular chaperone Hsp70 31.04 1 18 18 155 4.870E9 135.28 31.04 18 80 10029.54 29.12 16 75 625 67.2 4.18 HVO_2721 amidophosphoribosyltransferase 31.03 1 8 8 37 1.497E9 25.07 31.03 8 18 1448.15 28.80 7 19 493 53.4 4.78 HVO_1698 CBS/parB domain protein 30.94 1 6 7 14 7.095E8 1.84 24.53 5 7 404.44 23.77 6 7 265 29.4 4.92 HVO_0310 A-type ATP synthase subunit H 30.91 1 2 2 6 1.529E8 0.00 30.91 2 3 130.13 30.91 2 3 110 12.5 4.03 HVO_1084 adenylosuccinate lyase 30.89 1 11 11 39 4.823E8 30.99 26.57 10 20 2104.30 27.43 9 19 463 50.8 4.70 HVO_0417 metal-dependent carboxypeptidase 30.88 1 13 13 45 7.352E8 33.21 30.88 13 22 2330.35 30.88 13 23 502 57.3 4.42 HVO_2130 IclR family transcription regulator 30.88 1 7 7 27 3.608E8 22.44 22.06 5 11 1597.92 30.88 7 16 272 30.1 5.55 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 30 9.203E8 17.14 30.84 8 15 1449.24 30.84 8 15 415 44.4 4.41 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 30.75 1 10 10 34 8.864E8 19.79 30.75 10 17 1690.89 30.75 10 17 348 38.2 4.32 HVO_1660 DisA-N domain protein 30.48 1 6 6 19 6.805E8 20.12 24.91 5 9 1115.91 30.48 6 10 269 28.9 4.73 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 30.47 1 3 3 16 7.770E7 13.06 30.47 3 8 843.96 30.47 3 8 128 13.0 4.31 HVO_1854 histidine--tRNA ligase 30.39 1 10 10 44 1.180E9 41.01 30.39 10 24 2317.57 30.39 10 20 431 47.1 4.37 HVO_0874 beta-lactamase domain protein 30.31 1 15 15 76 2.484E9 63.75 28.91 14 39 4839.03 26.09 14 37 640 71.9 5.14 17318569 keratin 1 [Homo sapiens] 30.28 1 1 21 140 3.397E9 129.62 30.28 21 69 9155.63 30.28 21 71 644 66.0 8.12 HVO_1175 DUF2110 family protein 30.22 1 5 5 23 1.295E9 21.38 30.22 5 12 1480.01 30.22 5 11 225 24.4 4.63 HVO_1370 gamma-glutamyl phosphate reductase 30.18 1 10 10 43 1.189E9 33.68 25.68 9 21 2215.62 30.18 10 22 444 48.1 4.34 HVO_2336 pyridoxal biosynthesis lyase PdxS 30.13 1 6 6 52 4.725E8 33.57 26.49 5 24 2781.62 30.13 6 28 302 32.5 4.81 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 29.97 1 5 5 21 4.846E8 12.54 29.97 5 11 839.52 22.28 4 10 377 39.2 4.18 HVO_0008 aspartate kinase 29.85 1 9 9 58 4.290E9 41.76 29.85 9 28 2778.83 29.85 9 30 392 41.7 4.46 HVO_1172 NAD-dependent epimerase/dehydratase 29.84 1 6 6 30 1.973E9 18.87 29.84 6 15 1587.61 29.84 6 15 315 34.9 4.34 HVO_1123 thioredoxin-disulfide reductase 29.80 1 8 8 31 1.110E9 13.82 23.21 5 14 1638.13 20.63 7 17 349 37.3 4.32 HVO_1880 conserved hypothetical protein 29.78 1 5 5 17 1.312E8 10.50 29.78 5 8 728.05 29.78 5 9 225 23.8 4.59 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 29.74 1 8 8 27 4.487E8 20.88 26.65 7 13 1167.19 29.74 8 14 454 48.5 4.46 HVO_1657 phosphoribosylamine--glycine ligase 29.67 1 11 11 49 1.771E9 34.75 27.57 9 22 2759.17 29.67 11 27 428 45.5 4.20 40354192 keratin 10 [Homo sapiens] 29.45 1 0 17 85 1.018E9 55.07 29.28 16 42 4106.65 29.45 17 43 584 58.8 5.16 HVO_1577 conserved hypothetical protein 29.38 1 4 4 14 5.239E8 12.92 29.38 4 7 936.70 29.38 4 7 177 19.4 4.74 HVO_1488 D-gluconate dehydratase 29.37 1 8 10 66 2.381E9 39.96 29.37 10 32 3310.43 29.37 10 34 412 45.8 4.60 HVO_0792 3-dehydroquinate synthase type II 29.34 1 10 10 47 1.048E9 33.20 29.34 10 23 2409.05 29.34 10 24 392 43.1 4.44 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 29.20 1 9 9 46 2.641E9 41.96 29.20 9 23 2754.86 29.20 9 23 435 46.9 4.63 HVO_2688 TrmB family transcription regulator 29.18 1 8 8 30 1.121E9 27.00 29.18 8 16 2227.10 22.38 7 14 353 39.3 4.58 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 29.08 1 9 9 42 7.336E8 29.80 27.74 8 20 2442.58 29.08 9 22 447 48.5 4.56 HVO_0212 homolog to lactoylglutathione lyase 29.03 1 2 2 11 4.812E8 10.09 29.03 2 5 686.68 29.03 2 6 124 13.5 4.13 HVO_1727 TATA-binding transcription initiation factor 29.03 1 5 6 54 3.161E9 38.91 29.03 6 27 3250.63 29.03 6 27 186 19.9 4.36 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 29.01 1 0 17 85 1.018E9 55.07 28.84 16 42 4106.65 29.01 17 43 593 59.5 5.21 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 28.97 1 6 6 26 2.011E9 28.39 24.60 5 13 2054.31 28.97 6 13 252 26.0 4.39 HVO_1189 aldehyde dehydrogenase 28.94 1 12 12 57 1.247E9 40.59 25.20 10 27 2890.05 28.94 12 30 508 56.1 4.59 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 28.89 1 5 5 21 3.186E8 25.89 28.89 5 11 1454.79 28.89 5 10 270 29.1 4.35 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 28.88 1 0 20 136 3.397E9 127.84 28.88 20 67 8980.07 28.88 20 69 644 66.0 8.12 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 28.57 1 3 3 7 1.028E8 1.96 20.88 2 3 240.66 28.57 3 4 91 10.4 4.07 HVO_1291 fumarylacetoacetase family protein 28.40 1 3 3 6 1.680E9 2.27 25.93 2 2 244.97 28.40 3 4 243 26.3 4.55 HVO_0349 DNA-directed RNA polymerase subunit A' 28.18 1 22 22 117 1.093E9 105.73 27.66 21 60 6973.60 27.15 21 57 976 108.8 4.81 HVO_0357 ACT domain protein 28.04 1 5 5 22 1.027E9 14.73 28.04 5 13 841.73 24.87 4 9 189 20.2 4.59 HVO_1125 cysteine--tRNA ligase 27.94 1 10 10 37 3.485E8 20.76 27.94 10 19 1689.48 25.91 9 18 494 55.2 4.56 HVO_C0069 GFO family oxidoreductase 27.78 1 7 7 24 1.815E8 9.99 27.78 7 12 854.09 27.78 7 12 324 36.0 5.10 HVO_2454 anthranilate synthase component I 27.67 1 11 11 34 8.164E8 23.39 24.43 10 17 1717.70 26.15 10 17 524 55.9 4.56 HVO_2239 UspA domain protein 27.46 1 5 5 14 1.189E9 8.36 27.46 5 8 670.48 27.46 4 6 142 15.4 4.16 HVO_2040 NAD-dependent epimerase/dehydratase 27.45 1 4 7 47 1.447E9 44.40 27.45 7 23 2896.76 27.45 7 24 306 33.8 4.51 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 27.38 1 7 7 31 7.646E8 19.00 27.38 7 15 1547.21 27.38 7 16 336 38.0 4.61 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 27.11 1 10 10 26 9.569E8 10.73 24.30 9 12 1196.30 27.11 10 14 461 50.7 4.73 HVO_0041 ornithine carbamoyltransferase 27.09 1 5 5 23 7.206E8 15.53 27.09 5 12 1151.10 15.38 4 11 299 32.7 4.37 HVO_2225 AstE family protein 26.98 1 5 5 16 4.436E8 7.38 26.98 5 8 642.09 26.98 5 8 341 36.9 4.53 HVO_0354 30S ribosomal protein S7 26.96 1 5 5 18 1.288E9 14.42 26.96 5 9 978.60 26.96 5 9 204 22.6 5.14 HVO_0388 homolog to ribonuclease R 26.88 1 10 10 48 3.741E8 36.80 26.88 10 24 2765.95 26.88 10 24 439 50.3 4.73 HVO_0549 2-keto-3-deoxygluconate kinase 26.88 1 7 8 31 5.954E8 20.92 23.13 7 14 1829.37 26.88 8 17 320 34.1 4.34 HVO_1295 histidinol-phosphate aminotransferase 26.87 1 7 7 14 1.962E8 12.47 18.28 5 6 721.10 26.87 7 8 361 39.4 4.51 HVO_1478 transcription initiation factor TFB 26.81 1 5 8 38 1.173E9 32.52 26.81 8 19 2352.93 26.81 8 19 317 35.7 5.47 HVO_1654 cysteine synthase 26.80 1 5 5 10 6.064E8 7.85 19.61 4 4 487.25 26.80 5 6 306 32.3 4.32 HVO_0889 FAD-dependent oxidoreductase 26.64 1 2 2 2 6.081E7 273.39 26.64 2 2 214 21.8 3.89 HVO_0214 L-lactate dehydrogenase 26.56 1 8 8 49 2.737E9 50.10 23.75 7 24 3432.01 26.56 8 25 320 34.5 4.49 HVO_0109 cysteine desulfurase 26.53 1 9 9 30 8.317E8 27.31 21.60 7 14 2134.46 24.65 8 16 426 46.8 4.56 HVO_2496 adenylate kinase 26.44 1 5 5 29 1.777E9 25.51 26.44 5 15 1842.69 26.44 5 14 208 23.1 4.25 HVO_A0406 conserved hypothetical protein 26.42 1 1 7 33 7.146E8 27.35 26.42 7 16 2142.66 26.42 7 17 405 44.4 5.30 HVO_1989 tRNA (pseudouridine(54)-N(1))-methyltransferase 26.26 1 2 2 3 1.170E8 2.26 26.26 2 3 198 21.9 4.79 HVO_1623 conserved hypothetical protein 26.17 1 5 5 28 3.040E8 13.52 26.17 5 14 1065.22 26.17 5 14 298 32.8 4.56 HVO_2756 50S ribosomal protein L10 26.15 1 6 6 45 1.535E9 45.67 26.15 5 22 2968.68 26.15 6 23 348 36.9 3.99 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 14 3.041E8 10.67 26.15 3 7 851.53 26.15 3 7 130 13.4 8.56 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 26.00 1 8 8 31 3.126E8 14.32 26.00 8 15 1332.60 26.00 8 16 473 50.8 4.58 HVO_A0636 YbaK domain protein 25.95 1 3 3 11 2.577E8 13.23 25.95 3 6 492.86 22.15 2 5 158 16.7 4.54 HVO_1527 glucose-1-phosphate uridylyltransferase 25.93 1 6 6 32 5.687E8 25.67 25.93 6 15 1696.19 25.93 6 17 243 27.5 4.70 HVO_1576 NAD-dependent epimerase/dehydratase 25.82 1 4 7 35 7.669E8 37.59 25.82 7 17 2291.22 25.82 7 18 306 33.9 4.51 HVO_0233 ribose-phosphate pyrophosphokinase 25.80 1 4 4 10 4.694E8 8.40 25.80 4 5 581.82 25.80 4 5 283 29.6 4.40 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 25.79 1 19 19 76 5.652E8 77.01 21.63 16 37 5082.94 24.49 18 39 1082 117.2 4.32 HVO_0087 porphobilinogen synthase 25.69 1 6 6 16 2.087E8 11.73 25.69 6 8 560.50 25.69 6 8 327 35.3 4.72 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 25.68 1 9 9 53 2.383E9 41.05 23.24 8 25 3106.43 25.68 9 28 370 41.9 4.48 HVO_0795 transcription initiation factor TFB 25.67 1 3 7 18 2.879E8 15.95 23.28 6 8 1005.83 25.67 7 10 335 37.4 5.59 HVO_1778 catalase-peroxidase 25.63 1 13 13 79 2.550E9 67.47 25.63 13 38 5050.54 25.63 13 41 718 80.0 4.31 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 25.58 1 7 7 23 1.191E8 10.77 18.60 5 9 1268.71 25.58 7 14 344 39.1 4.73 HVO_1847 oligoendopeptidase PepF 25.38 1 11 11 41 3.294E8 14.63 25.38 11 20 1433.02 21.70 10 21 599 68.5 4.41 HVO_0694 probable phosphoribosyltransferase 25.32 1 6 6 18 2.077E8 10.96 25.32 6 9 705.91 25.32 6 9 237 27.0 4.32 HVO_0206 alanine--tRNA ligase 25.27 1 19 19 84 5.499E8 73.29 24.40 18 40 5105.70 25.27 19 44 922 102.4 4.54 HVO_2948 phenylalanine--tRNA ligase alpha subunit 25.25 1 6 6 33 5.270E8 13.42 25.25 6 17 1325.10 18.04 5 16 499 55.1 4.41 >sp|TRYP_PIG| 25.11 1 4 4 125 4.925E10 159.53 25.11 4 62 10591.02 25.11 4 63 231 24.4 7.18 HVO_2781 DNA-directed RNA polymerase subunit D 25.10 1 5 5 49 2.057E9 34.81 25.10 5 25 2795.62 25.10 5 24 259 28.1 4.32 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 24.93 1 8 8 57 3.051E9 57.72 24.93 8 30 3304.11 24.93 8 27 357 40.3 4.40 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 24.85 1 4 5 19 4.789E8 9.42 24.85 5 9 1088.54 24.85 5 10 330 36.3 4.35 HVO_1690 DHH family phosphoesterase 24.74 1 8 8 34 1.470E8 38.50 24.74 8 17 2216.41 24.74 8 17 485 52.1 4.48 HVO_B0061 precorrin-2 C20-methyltransferase 24.68 1 4 4 13 9.274E7 8.22 14.47 3 6 555.46 24.68 4 7 235 25.3 4.63 HVO_1649 methionine adenosyltransferase 24.63 1 6 6 17 4.359E8 11.34 24.63 6 9 639.91 21.39 5 8 402 43.5 4.45 HVO_2436 malic enzyme (NADP) 24.63 1 13 16 60 5.311E8 53.10 23.70 14 29 3638.88 24.50 15 31 751 81.4 4.55 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 24.59 1 5 5 10 1.311E8 4.98 24.59 5 6 344.85 22.30 4 4 305 32.7 4.56 HVO_0536 ferritin 24.43 1 2 2 8 2.129E8 11.04 24.43 2 4 344.50 24.43 2 4 176 19.9 4.50 HVO_1338 replication protein A 24.36 1 7 7 29 6.344E8 18.42 24.36 7 15 1304.12 24.36 7 14 427 46.0 4.36 HVO_0787 indole-3-glycerol-phosphate synthase 24.30 1 4 4 12 2.134E8 4.39 24.30 4 7 334.44 20.72 3 5 251 26.7 4.44 HVO_1573 DNA gyrase subunit A 24.25 1 19 19 72 1.081E9 56.32 23.67 18 35 3719.08 24.25 18 37 862 94.8 4.56 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 24.23 1 11 11 34 6.897E8 20.79 21.84 10 17 1660.00 24.23 11 17 586 63.4 4.70 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 24.21 1 8 8 39 8.430E8 36.20 24.21 8 20 1978.80 24.21 8 19 347 36.8 4.93 HVO_0393 UvrABC system protein A 24.21 1 20 20 78 4.085E8 54.04 23.19 19 39 3750.54 24.21 20 39 983 108.6 4.82 HVO_1496 phosphotransferase system component I 24.07 1 10 10 27 2.078E8 12.34 24.07 10 14 1119.01 24.07 10 13 565 60.3 4.21 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 23.83 1 9 9 35 4.878E8 36.06 23.83 9 17 2228.95 21.88 8 18 512 53.8 4.78 7428712 "keratin 1, type II, cytoskeletal - human" 23.79 1 0 17 116 2.543E9 105.05 23.79 17 57 7471.53 23.79 17 59 643 65.5 6.35 HVO_1932 2-D-hydroxyacid dehydrogenase 23.70 1 6 6 18 2.556E8 14.49 23.70 6 9 822.60 23.70 6 9 308 33.0 4.60 HVO_1076 sugar nucleotidyltransferase 23.60 1 6 6 26 1.011E9 20.72 23.60 6 13 1441.58 23.60 6 13 322 35.8 4.20 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 23.60 1 3 4 13 2.939E8 10.70 23.60 4 7 634.63 15.36 3 6 267 29.1 4.63 HVO_1025 acetyl-CoA C-acyltransferase 23.50 1 6 6 18 5.177E8 20.07 23.50 6 9 1403.69 23.50 6 9 383 40.7 4.56 HVO_0601 homoserine dehydrogenase 23.42 1 5 6 29 5.585E8 27.99 23.42 6 14 1955.57 23.42 6 15 316 32.2 4.25 HVO_2912 ThiJ/PfpI domain protein 23.38 1 2 2 8 7.474E7 2.43 23.38 2 4 278.83 23.38 2 4 201 20.9 4.36 HVO_2675 histidinol dehydrogenase 23.36 1 5 5 33 3.599E8 24.12 23.36 5 15 1755.43 23.36 5 18 428 45.4 4.50 HVO_0699 translation initiation factor aIF-2 alpha subunit 23.31 1 6 6 26 4.975E8 16.00 23.31 6 13 1328.76 23.31 6 13 266 29.5 4.46 HVO_2784 30S ribosomal protein S13 22.75 1 3 3 7 6.662E8 4.28 22.75 3 4 331.01 22.75 3 3 167 18.9 5.17 HVO_2256 DUF262 family protein 22.73 1 9 9 29 3.940E8 20.73 22.73 9 16 1347.32 14.94 7 13 462 54.9 4.89 HVO_2383 DNA repair and recombination protein RadB 22.71 1 4 4 7 3.941E7 5.76 17.90 3 4 362.91 17.90 3 3 229 24.6 5.02 HVO_1371 glutamate 5-kinase 22.59 1 4 4 15 9.146E8 12.58 22.59 4 8 978.35 22.59 4 7 301 32.0 4.25 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 22.50 1 4 4 21 4.663E8 18.69 13.06 3 9 1386.01 22.50 4 12 360 38.5 4.45 HVO_2779 50S ribosomal protein L18e 22.41 1 2 2 5 3.779E7 1.84 22.41 2 2 222.51 22.41 2 3 116 12.7 8.50 HVO_0467 PhoU/TrkA-C domain protein 22.39 1 7 7 24 1.354E8 18.69 20.15 6 11 1413.87 22.39 7 13 402 43.3 4.49 HVO_0573 endonuclease IV 22.34 1 4 4 19 9.718E8 14.64 22.34 4 10 1087.43 22.34 4 9 291 31.4 4.44 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 22.30 1 7 7 35 1.354E9 38.95 22.30 7 18 2232.88 22.30 7 17 453 47.5 4.63 HVO_0602 3-dehydroquinate dehydratase 22.27 1 4 4 11 2.001E8 5.38 22.27 4 5 512.91 22.27 4 6 247 27.3 4.51 HVO_2700 AAA-type ATPase (CDC48 subfamily) 22.15 1 14 15 41 4.823E8 23.50 19.36 13 19 1837.21 22.15 15 22 754 82.8 4.75 HVO_0876 methylglyoxal synthase 22.05 1 2 2 7 1.274E8 1.79 22.05 2 4 194.56 22.05 2 3 127 13.9 4.48 HVO_2690 GFO family oxidoreductase 21.86 1 7 7 27 1.381E9 12.42 16.67 6 13 1295.98 21.86 7 14 366 40.0 4.60 HVO_1391 NUDIX family hydrolase 21.85 1 3 3 10 7.491E7 6.93 21.85 3 5 370.92 21.85 3 5 151 17.4 5.01 HVO_0867 HD family hydrolase 21.74 1 4 4 10 1.344E8 9.16 21.74 4 5 537.46 21.74 4 5 230 26.2 4.78 HVO_1134 conserved hypothetical protein 21.66 1 10 10 30 2.449E8 25.51 18.89 9 15 1308.19 21.66 10 15 757 80.6 4.35 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 21.63 1 3 3 6 1.833E8 3.76 21.63 3 3 308.74 21.63 3 3 208 22.6 4.36 HVO_A0133 conserved hypothetical protein 21.58 1 5 5 14 2.620E8 12.82 21.58 5 7 702.87 21.58 5 7 292 30.8 5.17 HVO_0431 HAD superfamily hydrolase 21.48 1 3 3 3 1.197E7 0.00 21.48 3 3 284 30.4 4.26 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 21.45 1 6 6 23 9.226E8 12.35 21.45 6 12 1073.97 14.48 5 11 373 40.2 4.44 HVO_1373 acyl-CoA dehydrogenase 21.41 1 5 5 15 2.047E8 14.26 21.41 5 8 758.54 19.58 4 7 383 42.5 4.61 HVO_0429 archaemetzincin 21.39 1 2 2 3 9.845E7 1.71 21.39 2 3 173 19.3 6.54 HVO_2547 50S ribosomal protein L32e 21.28 1 4 4 18 2.220E8 21.55 21.28 4 9 1400.71 21.28 4 9 235 25.8 4.75 HVO_2156 UspA domain protein 21.26 1 5 5 24 1.138E9 16.69 21.26 5 12 1538.01 21.26 5 12 301 31.6 4.69 HVO_0937 FMN-binding domain protein 21.23 1 2 2 6 4.919E7 4.41 21.23 2 3 270.50 21.23 2 3 146 16.2 4.36 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 20.99 1 5 5 23 6.794E8 15.45 20.99 5 11 1160.08 20.99 5 12 362 39.6 4.82 HVO_1853 UspA domain protein 20.95 1 2 2 4 1.992E7 2.39 20.95 2 2 189.99 20.95 2 2 148 16.0 4.58 HVO_A0307 Lrp/AsnC family transcription regulator 20.90 1 3 3 10 8.371E7 4.07 20.90 3 5 482.63 20.90 3 5 177 19.4 4.39 HVO_0911 GTP-binding protein Drg 20.87 1 6 6 23 9.620E7 6.82 18.97 5 11 797.71 20.87 6 12 369 40.5 4.81 HVO_A0432 conserved hypothetical protein 20.74 1 0 6 27 3.815E8 24.82 20.74 6 13 1949.36 20.74 6 14 405 44.5 5.24 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 16 7.927E7 21.08 20.71 2 8 1433.87 20.71 2 8 140 16.0 5.57 HVO_1048 phosphoribosylformylglycinamidine synthase 2 20.66 1 9 9 44 7.258E8 59.33 19.66 8 21 3451.35 20.66 9 23 702 72.9 4.18 HVO_1531 UDP-glucose 6-dehydrogenase 20.47 1 7 7 19 3.442E8 4.38 14.19 5 8 685.34 20.47 7 11 430 45.9 4.50 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 20.38 1 4 4 16 9.055E7 16.75 20.38 4 8 653.41 20.38 4 8 265 29.3 4.92 HVO_0100 NMD3 family protein 20.27 1 5 5 11 8.086E7 6.48 12.80 3 4 424.30 20.27 5 7 375 41.6 4.46 HVO_0812 phosphoenolpyruvate synthase 20.24 1 10 10 25 1.985E8 24.26 20.24 10 13 1249.44 16.56 9 12 761 83.1 4.63 HVO_2790 ATP-binding protein Mrp 20.23 1 4 4 22 3.994E8 16.22 20.23 4 11 958.76 20.23 4 11 346 36.8 4.50 HVO_2961 dihydrolipoyl dehydrogenase 20.21 1 8 8 27 2.869E8 24.15 20.21 8 14 1235.76 17.89 7 13 475 49.9 4.41 HVO_1510 2-isopropylmalate synthase 20.00 1 6 6 27 2.300E9 28.14 20.00 6 15 1411.81 18.64 5 12 440 47.7 4.82 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 19.89 1 5 5 26 4.263E8 9.31 19.89 5 13 1231.55 19.89 5 13 357 39.8 4.41 HVO_A0496 UspA domain protein 19.66 1 5 5 14 1.999E8 4.20 11.03 3 6 483.96 19.66 5 8 290 31.4 4.60 HVO_1020 HEAT-PBS family protein 19.57 1 6 6 27 1.801E8 18.18 18.14 5 12 1606.73 19.57 6 15 419 45.5 3.95 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 19.57 1 2 2 14 3.469E8 2.34 19.57 2 6 436.11 19.57 2 8 184 20.0 4.75 HVO_0466 citrate (si)-synthase 19.53 1 6 6 36 1.165E9 21.28 19.53 6 19 1382.20 19.53 6 17 379 41.8 4.55 HVO_1879 enoyl-CoA hydratase 19.48 1 3 3 4 1.028E8 254.26 19.48 3 4 231 24.3 5.21 HVO_2580 L-aspartate oxidase 19.37 1 6 6 22 1.054E8 18.28 19.37 6 11 1169.26 19.37 6 11 537 55.8 4.63 HVO_0243 threonine aldolase 19.35 1 4 4 15 1.684E8 17.07 15.84 3 7 899.06 19.35 4 8 341 35.6 4.55 HVO_0407 conserved hypothetical protein 19.35 1 2 2 6 2.545E8 4.08 19.35 2 3 181.43 19.35 2 3 124 13.4 4.44 HVO_B0060 precorrin-4 C11-methyltransferase 19.35 1 2 2 4 1.168E8 2.44 19.35 2 2 58.51 19.35 2 2 279 29.7 4.22 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 30 2.265E9 26.61 15.61 4 15 1639.31 19.31 5 15 378 39.7 4.67 HVO_0017 conserved hypothetical protein 19.27 1 3 3 14 4.181E8 7.53 19.27 3 7 702.83 19.27 3 7 192 21.9 4.50 HVO_1783 conserved hypothetical protein 19.20 1 3 3 14 4.477E7 4.53 19.20 3 7 538.07 19.20 3 7 224 24.1 5.90 HVO_1547 isoleucine--tRNA ligase 19.18 1 14 14 57 7.041E8 49.13 16.30 13 28 3321.21 19.18 14 29 1043 117.9 4.30 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 19.17 1 4 4 10 3.812E8 0.00 16.06 3 6 104.37 14.77 3 4 386 42.1 4.49 HVO_1412 diphosphomevalonate decarboxylase 19.14 1 6 6 20 1.544E9 11.84 19.14 6 10 999.66 19.14 6 10 324 35.4 4.78 HVO_2643 NADPH:quinone reductase 19.08 1 4 4 15 3.590E8 5.65 19.08 4 7 678.43 19.08 4 8 346 37.2 4.55 HVO_1866 uridylate kinase 18.99 1 3 3 17 2.905E8 14.50 18.99 3 8 891.09 18.99 3 9 237 24.6 4.42 HVO_0541 aconitate hydratase 18.98 1 11 11 34 1.347E9 11.76 17.16 10 16 1437.15 18.98 11 18 938 102.1 4.40 HVO_1289 OsmC domain protein 18.94 1 2 2 14 1.442E9 20.48 18.94 2 7 1382.05 18.94 2 7 132 14.2 3.85 HVO_0034 acyl-CoA thioester hydrolase 18.90 1 2 2 14 2.834E8 9.61 18.90 2 7 602.26 18.90 2 7 164 18.3 4.65 HVO_A0458 ParA domain protein 18.90 1 3 3 9 1.865E8 8.90 18.90 3 4 602.89 18.90 3 5 291 32.2 4.79 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 18.87 1 4 4 14 2.131E8 11.45 18.87 4 7 682.73 15.09 3 7 265 28.7 4.87 HVO_2717 alanine--tRNA ligase 18.84 1 6 6 18 1.854E8 14.12 18.84 6 9 904.96 18.84 6 9 398 41.6 4.39 HVO_0697 PAC2 family protein 18.82 1 2 2 20 5.885E8 25.49 18.82 2 10 1267.69 18.82 2 10 255 27.4 4.08 HVO_1957 proteasome-activating nucleotidase 18.69 1 5 6 15 9.283E7 1.97 11.41 4 7 445.32 15.78 5 8 412 45.6 4.48 HVO_2879 ornithine cyclodeaminase 18.67 1 4 4 11 3.300E8 1.76 11.14 3 4 423.63 18.67 4 7 332 34.6 4.45 HVO_0970 ribulose-bisphosphate carboxylase large subunit 18.60 1 7 7 25 4.011E8 13.69 18.60 7 13 1281.83 14.01 6 12 414 43.9 4.59 HVO_0829 peptidase S9 family protein 18.59 1 7 7 30 3.623E8 19.12 16.45 6 15 1596.84 18.59 7 15 608 67.4 4.54 HVO_B0018 ParA domain protein 18.47 1 3 3 12 1.017E8 11.68 18.47 3 6 669.22 18.47 3 6 287 31.7 4.74 HVO_2960 dihydrolipoamide S-acyltransferase 18.43 1 7 7 19 1.759E8 15.70 18.43 7 10 961.50 16.89 6 9 521 54.9 4.40 HVO_1871 UPF0447 family protein 18.36 1 7 7 28 8.171E8 18.52 14.97 6 14 1272.57 18.36 7 14 501 56.1 4.59 HVO_1453 glutamate dehydrogenase (NADP) 18.23 1 6 6 15 3.100E8 7.68 18.23 6 8 553.26 16.31 5 7 417 45.7 4.49 HVO_1287 PfpI family protease 18.18 1 2 2 6 6.662E7 1.92 18.18 2 2 256.47 18.18 2 4 198 21.5 4.53 HVO_2548 50S ribosomal protein L6 17.98 1 2 2 14 2.577E8 12.23 17.98 2 6 793.12 17.98 2 8 178 19.6 4.68 HVO_2168 AAA-type ATPase (MoxR subfamily) 17.93 1 4 4 12 1.060E8 4.78 12.77 3 5 410.92 17.93 4 7 329 35.9 4.54 HVO_0123 signal recognition particle 54K protein 17.85 1 6 6 15 2.592E8 9.78 13.55 5 7 674.94 17.85 6 8 465 50.9 4.50 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 17.79 1 10 10 52 1.237E9 39.53 16.21 9 24 3193.36 17.79 10 28 697 74.5 4.13 HVO_2614 uridine phosphorylase 17.77 1 3 3 23 1.618E9 24.60 17.77 3 11 1412.49 17.77 3 12 242 25.8 4.30 HVO_0452 leucine--tRNA ligase 17.54 1 12 12 39 4.486E8 20.34 17.54 12 19 1959.19 17.54 12 20 958 109.5 4.37 HVO_1187 conserved hypothetical protein 17.48 1 2 2 5 3.581E7 0.00 17.48 2 2 155.25 17.48 2 3 143 16.4 4.86 HVO_0661 dCTP deaminase (dUMP-forming) 17.44 1 2 2 10 2.051E8 1.65 17.44 2 5 328.78 17.44 2 5 195 21.2 4.59 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 17.38 1 3 3 8 5.940E7 1.87 17.38 3 4 345.81 17.38 3 4 305 34.1 4.91 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 17.21 1 5 5 14 1.756E8 11.64 17.21 5 7 636.16 17.21 5 7 430 45.1 4.50 HVO_2712 3'-5' RNA ligase 17.08 1 6 6 15 1.234E8 10.97 12.76 5 7 692.62 17.08 6 8 486 53.4 4.92 HVO_A0452 UspA domain protein 17.06 1 4 4 8 4.431E7 0.00 17.06 4 4 278.46 17.06 4 4 293 31.3 4.63 HVO_2205 arNOG06768 family NADH-binding domain protein 16.94 1 4 4 13 4.989E7 12.37 16.94 4 6 805.93 16.94 4 7 301 32.0 5.00 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 16.91 1 6 6 22 5.503E8 17.16 16.91 6 11 1138.91 16.91 6 11 615 67.6 4.88 HVO_2348 GTP cyclohydrolase MptA 16.88 1 3 3 14 6.270E7 9.32 16.88 3 7 584.40 16.88 3 7 308 33.5 4.68 HVO_2189 phosphoribosylformylglycinamidine synthase component PurS 16.87 1 1 2 3 4.178E7 406.60 16.87 2 3 83 9.3 4.50 HVO_2947 phenylalanine--tRNA ligase beta subunit 16.84 1 7 7 31 6.265E8 22.05 14.91 6 15 1801.96 16.84 7 16 570 63.3 4.46 47132620 keratin 2a [Homo sapiens] 16.59 1 6 11 52 1.689E9 44.13 15.18 10 25 3083.96 16.59 11 27 639 65.4 8.00 HVO_1824 conserved hypothetical protein 16.55 1 5 5 18 1.188E9 18.70 12.35 4 8 1266.71 16.55 5 10 429 47.4 4.20 HVO_1571 DNA topoisomerase VI subunit B 16.54 1 9 9 40 6.301E8 41.92 16.54 9 20 2073.97 16.54 9 20 798 87.4 4.73 HVO_2923 proteasome alpha subunit 16.47 1 3 4 13 5.907E8 5.63 16.47 4 6 623.62 16.47 4 7 249 26.7 4.39 HVO_0402 DUF124 family protein 16.44 1 2 2 5 5.128E7 0.00 16.44 2 2 152.79 16.44 2 3 225 24.0 4.58 HVO_1344 SBDS family protein 16.39 1 3 3 10 6.371E7 5.32 16.39 3 5 393.04 16.39 3 5 238 26.5 4.51 HVO_1878 NAD synthase 16.30 1 4 4 16 2.869E8 6.59 16.30 4 8 625.05 16.30 4 8 276 29.6 4.37 HVO_2425 GNAT family acetyltransferase 16.20 1 3 3 10 1.289E8 4.76 16.20 3 5 365.97 16.20 3 5 216 24.4 4.54 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 16.16 1 8 8 33 9.061E8 10.02 16.16 8 16 1304.16 16.16 8 17 526 57.2 4.31 HVO_2763 homolog to ribonuclease Z 16.13 1 3 3 12 1.421E8 2.46 16.13 3 6 433.35 16.13 3 6 248 26.6 4.53 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 16.02 1 3 3 11 1.158E8 7.45 16.02 3 5 679.60 16.02 3 6 231 25.0 4.25 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 15.97 1 16 16 43 4.287E8 29.68 13.71 14 20 1771.04 15.97 16 23 1284 141.2 4.35 HVO_0551 DNA mismatch repair protein MutL 15.92 1 6 6 12 3.193E8 10.60 15.92 6 7 512.08 8.44 4 5 735 78.7 4.50 HVO_2554 50S ribosomal protein L14 15.91 1 2 2 5 2.279E8 4.67 15.91 2 2 291.51 15.91 2 3 132 14.2 9.76 HVO_1268 conserved hypothetical protein 15.61 1 3 3 8 5.681E7 4.34 15.61 3 4 288.55 15.61 3 4 237 26.4 5.21 HVO_1979 tRNA pseudouridine synthase Pus10 15.46 1 6 6 13 8.700E8 11.20 12.41 4 6 891.30 13.35 5 7 427 46.9 4.39 HVO_0158 TATA-binding transcription initiation factor 15.34 1 2 3 8 6.414E8 3.92 15.34 3 4 395.97 15.34 3 4 189 20.3 4.22 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 15.19 1 3 3 10 1.008E8 6.00 15.19 3 5 375.32 15.19 3 5 237 25.4 4.46 HVO_1164 HD family hydrolase 15.19 1 4 4 18 4.426E8 9.35 10.00 3 8 754.41 15.19 4 10 270 29.8 4.87 HVO_1073 ThiJ/PfpI family protein 15.18 1 3 3 12 7.499E7 14.07 15.18 3 6 697.04 15.18 3 6 224 23.9 4.12 HVO_2777 30S ribosomal protein S9 15.15 1 2 2 6 1.133E8 4.14 15.15 2 3 362.57 15.15 2 3 132 14.7 9.74 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 15.13 1 6 6 18 1.958E8 14.05 13.24 5 8 946.47 15.13 6 10 423 43.9 4.31 HVO_2708 YfiH family protein 14.91 1 3 3 14 3.749E8 11.88 14.91 3 8 586.36 10.56 2 6 322 35.4 4.35 HVO_1087 UspA domain protein 14.89 1 3 3 8 1.437E8 7.47 14.89 3 4 493.77 14.89 3 4 141 15.2 4.98 HVO_B0149 oleate hydratase 14.82 1 5 6 16 4.711E8 2.08 13.88 5 7 459.73 14.82 6 9 533 60.1 4.64 HVO_1562 proteasome beta subunit 14.81 1 3 3 10 2.105E8 6.45 14.81 3 5 353.98 14.81 3 5 243 26.0 4.63 HVO_1139 squalene synthase 14.80 1 3 3 6 7.481E7 3.45 14.80 3 3 197.63 14.80 3 3 358 39.7 4.54 HVO_2313 siroheme decarboxylase AhbB 14.73 1 2 2 8 6.104E8 7.82 14.73 2 4 453.33 14.73 2 4 353 39.6 4.64 HVO_2945 valine--tRNA ligase 14.71 1 10 10 53 9.675E8 31.48 11.26 8 25 3037.13 14.71 10 28 870 98.9 4.36 HVO_1967 glucose-6-phosphate isomerase 14.65 1 4 4 13 3.246E8 5.75 14.65 4 6 672.87 14.65 4 7 430 45.6 4.40 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 14.62 1 4 4 11 6.913E7 4.28 14.62 4 6 337.49 14.62 4 5 383 42.0 4.49 HVO_2068 "FtsZ family protein, type III" 14.59 1 4 4 14 3.933E8 14.45 14.59 4 7 879.48 14.59 4 7 370 38.7 4.49 HVO_1918 probable metallo-beta-lactamase family hydrolase 14.57 1 2 2 2 8.571E7 2.62 14.57 2 2 302 34.0 4.55 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 14.52 1 4 4 13 2.779E8 10.23 14.52 4 7 589.74 13.11 3 6 427 45.4 4.56 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 14.43 1 2 2 4 1.329E8 0.00 14.43 2 2 137.75 14.43 2 2 97 10.8 4.53 HVO_2373 30S ribosomal protein S8e 14.40 1 2 2 2 1.962E8 1.92 14.40 2 2 125 13.6 10.48 HVO_1823 UspA domain protein 14.38 1 2 2 6 2.802E8 4.74 14.38 2 3 394.94 14.38 2 3 153 16.4 4.60 HVO_2951 tryptophan--tRNA ligase 14.37 1 5 5 12 1.688E8 3.56 14.37 5 6 345.00 14.37 5 6 529 59.1 4.53 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 14.25 1 4 4 14 2.182E8 6.35 14.25 4 7 609.50 14.25 4 7 365 39.0 4.61 HVO_2501 alpha/beta hydrolase fold protein 14.24 1 3 3 10 4.027E7 8.88 14.24 3 5 422.63 14.24 3 5 316 35.3 5.72 HVO_0916 diphthine synthase 14.13 1 2 2 4 2.789E8 2.20 14.13 2 2 77.54 14.13 2 2 269 29.1 4.54 HVO_2435 peptidase M24 family protein 14.13 1 4 4 14 1.407E8 9.07 12.77 3 7 648.19 14.13 4 7 368 40.0 4.53 HVO_0658 tRNA pseudouridine(13) synthase TruD 14.04 1 4 4 8 1.271E8 1.84 11.66 3 3 265.87 14.04 4 5 463 50.6 4.70 HVO_1235 creatininase 14.02 1 3 3 9 6.149E7 3.90 14.02 3 5 257.85 14.02 3 4 264 29.2 4.84 HVO_1372 pyrroline-5-carboxylate reductase 14.01 1 3 3 8 2.201E8 5.79 14.01 3 4 456.15 14.01 3 4 257 26.8 4.01 HVO_1816 dihydroorotase 13.99 1 5 5 12 1.309E8 3.73 11.66 4 6 438.12 11.42 4 6 429 45.4 4.40 HVO_2333 conserved hypothetical protein 13.96 1 4 4 7 1.337E8 3.87 7.79 3 3 295.31 13.96 4 4 308 34.9 4.54 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 13.92 1 2 2 2 6.651E7 0.00 13.92 2 2 388 41.9 4.35 HVO_0134 KH domain protein 13.89 1 2 2 4 4.911E7 5.19 13.89 2 2 120.55 13.89 2 2 180 19.9 4.94 HVO_2008 archaeosine synthase 13.85 1 7 7 18 5.612E8 8.88 13.85 7 9 674.48 13.85 7 9 585 64.9 4.81 HVO_2600 methionyl aminopeptidase 13.85 1 4 4 12 3.197E8 6.35 9.80 3 5 615.30 13.85 4 7 296 32.3 4.41 HVO_0234 conserved hypothetical protein 13.82 1 2 2 10 4.419E7 4.60 13.82 2 5 365.01 13.82 2 5 275 28.1 4.48 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 10 2.986E8 5.75 13.66 2 5 495.24 13.66 2 5 183 20.0 4.21 HVO_3014 origin-associated GTP-binding protein OapA 13.62 1 2 2 2 2.364E8 1.64 13.62 2 2 213 24.0 5.01 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 13.49 1 5 5 19 4.108E8 5.43 13.49 5 10 816.90 11.40 4 9 430 44.2 4.37 HVO_0054 glycine--tRNA ligase 13.47 1 6 6 23 2.227E9 22.27 9.93 4 10 2007.52 13.47 6 13 594 64.9 4.21 HVO_2536 CHP00300 family protein 13.46 1 3 3 9 3.530E8 2.17 13.46 3 4 255.45 13.46 3 5 416 44.8 4.51 HVO_0681 DNA topoisomerase I 13.45 1 9 9 27 1.035E8 12.10 12.14 8 13 1244.05 13.45 9 14 840 93.6 4.58 HVO_2716 acyl-CoA dehydrogenase 13.39 1 3 3 7 1.494E7 0.00 13.39 3 4 244.19 6.56 2 3 381 41.3 4.65 HVO_1299 HTH domain protein 13.29 1 2 2 4 3.551E5 0.00 13.29 2 2 133.50 13.29 2 2 173 18.9 4.84 HVO_2153 probable copper-containing oxidoreductase 13.25 1 4 4 15 1.902E8 13.17 11.43 3 7 764.41 13.25 4 8 385 42.1 5.82 HVO_A0388 Lrp/AsnC family transcription regulator 13.22 1 2 2 6 1.273E8 0.00 13.22 2 3 140.32 13.22 2 3 174 20.1 4.86 HVO_0044 acetylglutamate kinase 13.15 1 3 3 13 3.622E8 9.71 13.15 3 7 680.22 13.15 3 6 327 33.2 4.49 HVO_1323 "shikimate kinase, archaeal-type" 13.15 1 3 3 17 2.949E8 11.34 13.15 3 8 999.64 13.15 3 9 289 29.5 4.30 HVO_1804 nicotinate phosphoribosyltransferase 13.14 1 5 5 12 2.306E8 7.72 10.05 4 5 500.75 13.14 5 7 388 41.1 4.60 HVO_0600 ACT domain protein 12.99 1 2 2 6 5.682E8 6.54 12.99 2 3 309.07 12.99 2 3 177 19.2 4.44 HVO_0894 acyl-CoA synthetase 12.99 1 3 5 16 1.789E8 11.62 12.99 5 8 618.98 12.99 5 8 662 74.3 4.48 HVO_2072 S-layer glycoprotein 12.82 1 5 5 67 2.488E9 44.94 12.82 5 35 2020.67 12.82 5 32 827 85.1 3.65 HVO_B0066 Lrp/AsnC family transcription regulator 12.80 1 2 2 4 4.878E7 1.62 12.80 2 2 168.74 12.80 2 2 164 18.5 4.41 HVO_1098 diaminopimelate decarboxylase 12.77 1 3 3 6 3.008E8 4.72 12.77 3 3 208.05 12.77 3 3 415 44.4 5.02 HVO_1327 AAA-type ATPase (CDC48 subfamily) 12.77 1 5 6 15 2.688E8 9.31 9.78 5 7 568.25 12.77 6 8 736 78.1 4.88 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 12.71 1 4 4 9 1.286E8 4.16 12.71 4 5 230.54 12.71 4 4 661 71.0 4.35 HVO_1508 acetolactate synthase large subunit 12.61 1 5 5 29 4.630E8 27.02 12.61 5 14 1756.44 12.61 5 15 587 62.3 4.36 HVO_2639 DUF1611 family protein 12.61 1 4 4 10 2.940E7 6.73 12.61 4 5 575.37 12.61 4 5 341 36.3 4.44 HVO_2706 translation initiation factor aIF-2B delta subunit 12.41 1 2 2 10 5.291E8 8.87 12.41 2 5 527.02 12.41 2 5 282 30.7 4.42 HVO_2883 conserved hypothetical protein 12.39 1 7 7 15 1.131E8 8.03 12.39 7 8 656.59 12.39 7 7 702 78.9 4.48 HVO_0042 acetylornithine deacetylase 12.34 1 3 3 8 7.922E8 7.26 12.34 3 4 505.61 7.87 2 4 381 41.0 4.34 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.27 1 2 2 12 3.898E8 4.77 12.27 2 6 618.59 12.27 2 6 269 28.3 4.49 HVO_0197 PurE family protein 12.25 1 3 3 5 7.030E7 0.00 8.70 2 2 115.32 12.25 3 3 253 25.5 4.42 HVO_1097 diaminopimelate epimerase 12.15 1 3 3 20 1.852E8 11.74 12.15 3 10 916.45 12.15 3 10 288 29.9 4.48 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 12.07 1 3 3 5 8.819E7 0.00 9.19 2 2 123.05 12.07 3 3 381 40.5 4.51 HVO_1676 transcription initiation factor TFB 12.05 1 0 3 9 2.525E8 9.03 9.64 2 4 514.94 12.05 3 5 332 37.3 5.49 HVO_1491 HAD superfamily hydrolase 12.01 1 4 4 15 9.959E7 6.11 12.01 4 7 909.43 12.01 4 8 408 44.4 4.60 HVO_C0001 Orc1-type DNA replication protein 12.01 1 5 5 16 1.051E8 7.28 12.01 5 8 734.92 12.01 5 8 408 45.2 4.97 HVO_0997 peptidase M24 family protein 11.96 1 2 2 9 4.830E7 5.94 11.96 2 4 344.21 11.96 2 5 368 39.9 4.49 HVO_B0059 cobalt-precorrin 5A hydrolase 11.96 1 3 3 10 1.824E8 11.67 11.96 3 5 565.02 11.96 3 5 326 34.5 4.51 HVO_1174 transcription initiation factor TFE 11.93 1 2 2 2 9.359E7 205.86 11.93 2 2 176 20.6 4.23 HVO_2662 homolog to lactoylglutathione lyase 11.85 1 3 3 9 5.167E7 8.06 11.85 3 4 484.21 11.85 3 5 329 36.5 4.48 HVO_2412 Lrp/AsnC family transcription regulator 11.80 1 2 2 4 6.476E7 0.00 11.80 2 2 138.12 11.80 2 2 161 17.7 4.55 HVO_A0266 IclR family transcription regulator 11.76 1 2 2 12 1.048E8 17.35 11.76 2 6 1208.12 11.76 2 6 255 27.7 6.05 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 11.76 1 4 4 13 7.467E7 11.19 11.76 4 7 545.47 9.73 3 6 442 46.9 4.58 HVO_0195 ribose-5-phosphate isomerase 11.74 1 2 2 8 4.477E8 4.36 11.74 2 4 356.33 11.74 2 4 230 23.2 4.54 HVO_0228 ParA domain protein 11.74 1 2 2 4 3.433E8 563.91 11.74 2 4 247 24.6 4.16 HVO_A0403 ISHwa16-type transposase ISHvo16 11.71 1 2 2 2 2.728E7 71.42 11.71 2 2 333 38.1 4.88 HVO_0979 NADH dehydrogenase-like complex subunit B 11.59 1 3 3 8 2.884E8 7.03 11.59 3 4 419.51 11.59 3 4 233 26.1 5.01 HVO_0552 DNA mismatch repair protein MutS 11.58 1 7 7 19 2.800E8 8.13 10.17 6 9 745.22 8.55 6 10 924 99.2 4.65 HVO_1348 probable YjeF family carbohydrate kinase 11.51 1 3 3 9 1.207E8 7.43 11.51 3 4 395.96 11.51 3 5 478 48.8 4.45 HVO_2001 tRNA-guanine(15) transglycosylase 11.43 1 3 3 10 1.050E8 7.30 11.43 3 5 500.06 11.43 3 5 516 56.3 4.59 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 11.42 1 3 3 16 1.937E8 7.06 11.42 3 8 620.11 11.42 3 8 464 53.1 4.54 HVO_0853 DNA double-strand break repair protein Mre11 11.34 1 3 3 8 1.400E8 7.50 11.34 3 4 450.53 11.34 3 4 441 48.1 4.39 HVO_2759 peptidase M42 family protein 11.30 1 4 4 15 4.999E8 11.85 11.30 4 7 815.73 11.30 4 8 354 37.0 4.40 HVO_1129 conserved hypothetical protein 11.28 1 2 3 8 1.339E8 4.05 10.00 2 3 369.66 11.28 3 5 390 43.0 4.44 HVO_1337 rpa-associated protein 11.24 1 6 6 19 8.223E8 8.25 11.24 6 11 711.79 8.19 4 8 623 64.8 3.68 HVO_2227 siroheme decarboxylase AhbA 11.24 1 2 2 9 7.321E7 8.08 11.24 2 4 485.01 11.24 2 5 347 39.1 4.69 HVO_2564 50S ribosomal protein L3 11.24 1 3 3 16 2.286E8 13.15 11.24 3 7 790.66 11.24 3 9 338 37.2 6.68 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 11.18 1 0 4 10 1.944E9 10.04 3.95 2 4 731.96 11.18 4 6 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 11.18 1 0 4 10 1.944E9 10.04 3.95 2 4 731.96 11.18 4 6 456 49.2 4.77 HVO_1465 naphthoate synthase 11.15 1 3 3 8 2.983E8 1.73 11.15 3 4 243.30 11.15 3 4 305 33.9 4.83 HVO_2918 thymidylate synthase 11.14 1 2 2 8 1.209E8 6.35 11.14 2 4 367.23 11.14 2 4 332 37.5 4.61 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 11.07 1 2 2 2 6.057E7 60.85 11.07 2 2 280 30.0 4.92 HVO_0469 AstE family protein 11.01 1 3 3 11 1.988E8 9.03 11.01 3 6 458.35 11.01 3 5 318 33.9 5.85 HVO_0326 CTP-dependent riboflavin kinase 10.97 1 3 3 7 3.037E7 1.88 10.97 3 4 206.40 6.75 2 3 237 25.9 4.55 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 10.91 1 6 6 15 1.749E8 12.35 8.36 5 7 862.10 10.91 6 8 706 73.3 4.39 HVO_1503 3-isopropylmalate dehydratase small subunit 10.89 1 2 2 9 3.305E8 6.28 10.89 2 4 359.12 10.89 2 5 202 22.0 4.15 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 10.86 1 2 2 2 2.586E9 115.75 10.86 2 2 175 18.8 4.63 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 10.83 1 2 2 5 2.644E8 716.71 10.83 2 5 277 30.6 4.30 HVO_1711 glucoamylase 10.72 1 11 11 22 1.492E8 9.83 9.07 9 11 670.81 9.86 10 11 1511 166.1 4.64 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 10.63 1 3 3 9 7.629E7 5.70 7.09 2 4 547.11 10.63 3 5 395 42.4 4.54 HVO_1356 sensor box histidine kinase 10.55 1 3 3 13 1.332E8 11.62 10.55 3 6 701.73 10.55 3 7 550 61.1 4.60 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 10.53 1 2 2 4 9.618E7 0.00 10.53 2 2 81.99 10.53 2 2 323 34.9 5.24 HVO_1895 KEOPS complex subunit Kae1/Bud32 10.51 1 4 4 10 1.146E8 7.15 10.51 4 5 476.84 10.51 4 5 552 59.0 5.07 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 10.49 1 2 2 8 1.908E8 8.46 10.49 2 4 703.46 10.49 2 4 324 36.6 4.68 HVO_2380 AAA-type ATPase (CDC48 subfamily) 10.36 1 7 7 18 8.930E7 6.51 9.02 6 9 715.26 10.36 7 9 743 81.9 4.82 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 10.34 1 3 3 6 1.212E8 4.79 10.34 3 3 231.62 10.34 3 3 406 45.5 5.08 HVO_2793 conserved hypothetical protein 10.32 1 2 2 4 5.800E7 3.76 10.32 2 2 197.16 10.32 2 2 252 27.1 4.46 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 10.10 1 3 3 10 1.586E8 2.56 10.10 3 5 288.81 10.10 3 5 584 63.3 4.79 HVO_1656 YyaL family protein 10.10 1 5 5 9 2.792E7 1.73 8.82 4 4 280.05 10.10 5 5 703 77.3 4.49 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 7 1.123E8 3.92 10.00 2 3 375.58 10.00 2 4 190 21.0 4.74 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 9.92 1 2 2 13 5.377E8 11.45 9.92 2 6 927.38 9.92 2 7 363 39.7 4.25 HVO_A0331 D-galactonate dehydratase 9.90 1 2 2 2 1.116E8 123.60 9.90 2 2 384 42.8 4.83 HVO_B0371 aldehyde dehydrogenase 9.88 1 3 3 8 8.660E7 2.24 9.88 3 4 262.94 9.88 3 4 496 52.5 4.39 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 9.79 1 3 3 5 1.299E8 1.67 7.12 2 2 157.01 9.79 3 3 337 35.9 4.69 HVO_B0055 conserved hypothetical protein 9.78 1 2 2 4 3.512E8 0.00 9.78 2 2 143.61 9.78 2 2 225 23.9 4.69 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 9.57 1 2 2 12 2.680E8 11.89 9.57 2 6 822.47 9.57 2 6 324 33.6 3.99 HVO_2761 mevalonate kinase 9.54 1 2 2 3 6.020E7 5.91 9.54 2 3 367 38.2 4.31 HVO_A0003 ParA domain protein 9.49 1 2 2 2 2.914E7 84.88 9.49 2 2 274 30.3 4.53 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 9.44 1 2 2 4 5.732E7 2.65 9.44 2 2 163.98 9.44 2 2 339 38.1 4.50 21961227 Keratin 6B [Homo sapiens] 9.40 1 1 6 41 5.440E8 32.81 7.80 5 20 2271.28 9.40 6 21 564 60.0 8.00 HVO_2160 conserved hypothetical protein 9.35 1 13 13 86 1.274E9 91.62 8.20 12 43 5412.70 9.35 13 43 2257 232.7 3.92 HVO_C0067 FAD-dependent oxidoreductase 9.34 1 2 2 3 4.621E7 5.63 9.34 2 3 396 42.7 4.30 HVO_2229 flavin-containing amine-oxidoreductase 9.30 1 2 2 6 9.237E7 2.30 9.30 2 3 193.55 9.30 2 3 344 37.9 4.92 HVO_1594 tRNA/rRNA cytosine-C5-methylase 9.27 1 2 2 7 1.644E8 7.14 9.27 2 3 401.00 9.27 2 4 313 34.6 4.69 HVO_0122 phosphoglycerate dehydrogenase 9.26 1 2 2 2 4.048E7 137.34 9.26 2 2 324 35.3 5.35 HVO_2350 YyaL family protein 9.24 1 3 3 7 1.272E8 6.97 6.52 2 3 325.00 9.24 3 4 552 58.8 4.59 HVO_0768 radical SAM domain protein 9.20 1 2 2 4 5.122E7 0.00 9.20 2 2 47.36 9.20 2 2 565 62.0 4.84 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 9.15 1 4 4 10 1.158E8 7.02 9.15 4 5 451.19 9.15 4 5 634 66.1 4.54 HVO_0069 sulfatase 9.13 1 3 3 4 2.438E8 0.00 5.63 2 2 87.49 6.02 2 2 515 57.4 4.35 HVO_2481 HD family hydrolase 8.97 1 2 2 5 4.244E7 0.00 8.97 2 2 140.58 8.97 2 3 390 42.7 6.14 HVO_2707 GFO family oxidoreductase 8.87 1 3 3 11 1.383E8 8.57 8.87 3 5 602.34 8.87 3 6 372 41.0 4.55 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 8.85 1 0 4 31 4.338E8 24.57 8.85 4 15 1809.08 8.85 4 16 384 42.4 5.40 HVO_2581 quinolinate synthase A 8.83 1 3 3 10 1.345E8 1.94 5.71 2 4 474.69 8.83 3 6 385 42.0 4.41 HVO_1079 sulfate adenylyltransferase small subunit 8.62 1 3 3 7 6.112E6 3.83 5.23 2 3 369.99 8.62 3 4 325 37.5 4.18 HVO_2427 replication factor C large subunit 8.61 1 4 4 11 1.713E8 6.07 8.61 4 6 430.21 8.61 4 5 488 53.4 4.67 HVO_0733 transcription initiation factor TFB 8.59 1 0 3 12 7.666E8 11.87 8.59 3 6 841.73 8.59 3 6 326 37.2 6.00 HVO_0818 threonine synthase 8.48 1 3 3 18 3.453E8 15.63 8.48 3 9 1029.89 8.48 3 9 389 40.8 4.31 HVO_B0115 fumarylacetoacetase family protein 8.48 1 2 2 12 4.480E8 7.62 8.48 2 6 587.13 8.48 2 6 283 30.3 4.21 HVO_B0256 aldehyde ferredoxin oxidoreductase 8.47 1 3 3 8 1.232E8 1.85 8.47 3 4 256.03 8.47 3 4 555 59.9 4.55 HVO_2908 dihydropteroate synthase 8.44 1 3 3 11 4.493E7 1.61 8.44 3 5 303.71 8.44 3 6 379 40.8 4.53 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 8.33 1 2 2 2 1.074E8 90.82 8.33 2 2 420 45.0 4.86 HVO_1383 tRNA (adenine-N(1))-methyltransferase TrmI 8.30 1 2 2 4 6.923E7 0.00 8.30 2 2 119.03 8.30 2 2 241 26.1 4.58 HVO_A0087 fumarylacetoacetase family protein 8.30 1 2 2 4 6.127E8 488.88 8.30 2 4 289 32.0 4.21 HVO_0585 probable oxidoreductase (aldo-keto reductase family protein) 8.26 1 2 2 6 6.858E7 1.70 8.26 2 3 215.86 8.26 2 3 327 36.2 4.63 HVO_B0038A D-xylonate dehydratase 8.25 1 1 3 12 5.084E8 4.56 8.25 3 7 490.41 4.61 2 5 412 45.5 4.55 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 8.24 1 1 2 2 1.934E8 1.86 8.24 2 2 267 28.8 4.55 HVO_0868 NAD-dependent epimerase/dehydratase 8.21 1 3 3 9 2.190E8 2.09 4.26 2 4 339.33 8.21 3 5 329 36.1 4.55 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 8.21 1 2 2 4 2.434E7 2.04 8.21 2 2 196.83 8.21 2 2 268 27.9 4.87 HVO_0048 argininosuccinate lyase 8.20 1 3 3 10 2.113E8 3.34 8.20 3 5 338.92 8.20 3 5 488 50.8 4.53 HVO_1309 peptidase M24 family protein 8.18 1 3 3 10 1.940E7 9.61 8.18 3 5 529.21 8.18 3 5 391 42.1 4.36 HVO_0968 NADH dehydrogenase-like complex subunit CD 8.16 1 0 4 14 5.529E8 11.95 8.16 4 7 831.86 8.16 4 7 564 63.3 4.60 HVO_1629 conserved hypothetical protein 8.10 1 3 3 5 8.439E7 1.61 3.77 2 2 134.52 8.10 3 3 531 56.3 4.69 HVO_0322 MinD/ParA domain protein 8.09 1 2 2 8 7.415E7 3.31 8.09 2 4 329.42 8.09 2 4 581 58.8 3.70 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 8.02 1 2 2 8 5.681E7 9.69 8.02 2 4 325.29 8.02 2 4 349 37.0 4.70 HVO_1914 acetyl-CoA C-acyltransferase 7.96 1 2 2 6 3.499E7 6.19 7.96 2 3 318.43 7.96 2 3 377 39.9 4.41 HVO_1568 alpha/beta hydrolase fold protein 7.94 1 2 2 6 4.377E7 4.38 7.94 2 3 405.89 7.94 2 3 277 29.4 4.94 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 7.93 1 3 3 7 1.507E8 2.03 7.93 3 3 280.68 7.93 3 4 492 52.1 4.83 HVO_2266 hypothetical protein 7.91 1 3 3 12 1.567E8 3.68 7.91 3 6 565.63 7.91 3 6 493 56.7 4.54 HVO_1500 1-phosphofructokinase 7.87 1 2 2 3 4.209E7 192.55 7.87 2 3 305 32.0 4.51 HVO_0854 DNA double-strand break repair ATPase Rad50 7.84 1 5 5 11 6.813E7 5.85 7.84 5 6 440.71 6.83 4 5 893 100.0 4.58 HVO_B0001 Orc1-type DNA replication protein 7.80 1 3 3 5 8.544E7 3.77 7.80 3 3 99.96 5.61 2 2 410 45.8 5.33 HVO_1683 4-alpha-glucanotransferase 7.66 1 3 3 6 3.332E8 0.00 3.63 2 3 181.40 5.85 2 3 496 56.3 4.45 HVO_A0150 TrmB family transcription regulator 7.63 1 2 2 2 1.902E8 155.37 7.63 2 2 354 39.0 4.63 HVO_1570 DNA topoisomerase VI subunit A 7.38 1 2 2 6 1.964E8 4.64 7.38 2 3 320.27 7.38 2 3 366 41.8 4.63 HVO_1375 O-succinylbenzoic acid--CoA ligase 7.33 1 3 3 8 1.023E8 5.60 7.33 3 4 342.88 7.33 3 4 614 64.7 4.28 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 7.32 1 2 2 4 7.548E7 2.39 7.32 2 2 140.66 7.32 2 2 287 31.8 4.93 HVO_2456 anthranilate phosphoribosyltransferase 7.25 1 2 2 4 6.065E7 0.00 7.25 2 2 100.20 7.25 2 2 331 33.8 4.35 HVO_2421 probable DNA-binding protein 7.23 1 2 2 6 6.242E7 3.51 7.23 2 3 258.03 7.23 2 3 235 25.8 4.89 HVO_0826 peptidase M42 family protein 7.18 1 2 2 4 1.566E7 2.38 7.18 2 2 204.25 7.18 2 2 348 37.7 4.54 HVO_1685 conserved hypothetical protein 7.11 1 3 3 10 1.417E8 2.75 7.11 3 5 435.86 7.11 3 5 492 54.5 5.74 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 8 1.883E8 11.32 7.07 2 4 589.43 7.07 2 4 297 32.3 3.98 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 7.04 1 3 3 7 1.171E8 4.84 7.04 3 4 294.51 4.52 2 3 398 43.4 4.37 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 7.00 1 2 2 7 3.872E7 6.09 7.00 2 3 317.52 7.00 2 4 400 44.2 4.32 HVO_2605 MiaB-like tRNA modifying enzyme 6.99 1 2 2 2 2.038E7 118.56 6.99 2 2 429 47.4 5.03 4557890 keratin 5 [Homo sapiens] 6.95 1 0 5 31 4.338E8 22.64 6.95 5 15 1690.84 6.95 5 16 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 6.95 1 0 5 31 4.338E8 22.64 6.95 5 15 1690.84 6.95 5 16 590 62.4 8.06 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 11 8.589E8 1.88 5.40 2 5 431.84 6.94 3 6 389 40.8 4.89 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 6.86 1 4 4 15 4.754E8 16.06 5.39 3 7 1141.50 6.86 4 8 612 67.3 4.16 HVO_0464 threonine ammonia-lyase 6.70 1 2 2 4 6.196E7 2.06 6.70 2 2 148.97 6.70 2 2 403 43.7 4.72 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 6.69 1 2 2 12 6.951E8 11.32 6.69 2 6 672.89 6.69 2 6 299 32.0 4.53 HVO_B0057 precorrin-3B C17-methyltransferase 6.69 1 2 2 8 2.248E8 9.20 6.69 2 4 727.54 6.69 2 4 344 36.3 4.31 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 6.67 1 2 2 8 6.357E7 10.26 6.67 2 4 517.77 6.67 2 4 360 39.5 4.31 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 6.67 1 2 2 5 1.072E8 0.00 6.67 2 3 63.75 6.67 2 2 345 37.0 3.95 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 6.67 1 2 2 2 1.325E8 142.31 6.67 2 2 345 36.9 4.68 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 6.39 1 2 2 6 1.332E8 0.00 6.39 2 3 262.68 6.39 2 3 266 29.7 4.32 HVO_0755 NAD-dependent epimerase/dehydratase 6.38 1 2 2 2 5.976E7 3.64 6.38 2 2 298 32.3 4.91 HVO_C0042 helicase domain protein 6.36 1 6 6 22 1.793E8 6.21 6.36 6 11 875.08 6.36 6 11 1274 144.4 4.67 HVO_0662 HTH domain protein / thiamine-phosphate synthase 6.35 1 2 2 7 4.437E7 4.12 6.35 2 3 357.84 6.35 2 4 299 31.9 4.44 HVO_1565 DNA ligase (ATP) 6.32 1 3 3 7 1.161E8 2.00 6.32 3 3 236.94 6.32 3 4 585 62.7 4.44 HVO_2158 malic enzyme (NADP) 6.26 1 0 3 12 9.838E7 7.20 6.26 3 6 472.92 6.26 3 6 751 81.4 4.55 HVO_B0324 conserved hypothetical protein 6.24 1 2 2 4 7.786E7 2.24 6.24 2 2 138.70 6.24 2 2 449 48.0 4.58 HVO_0406 RNA-binding protein AU-1 6.20 1 2 2 8 1.762E8 5.87 6.20 2 4 357.84 6.20 2 4 468 49.9 4.53 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 6.20 1 2 2 6 1.452E7 5.55 6.20 2 3 273.76 6.20 2 3 403 41.1 4.73 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 6.20 1 2 2 10 5.669E7 6.83 6.20 2 5 429.29 6.20 2 5 516 56.7 4.89 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 6.08 1 2 2 8 1.090E8 3.93 6.08 2 4 301.44 6.08 2 4 378 39.8 4.45 HVO_1058 TrkA domain protein 6.07 1 2 2 8 2.651E8 8.66 6.07 2 4 468.03 6.07 2 4 445 47.7 4.35 HVO_0321 peptide chain release factor aRF-1 6.04 1 2 2 9 3.588E8 4.11 6.04 2 5 356.25 6.04 2 4 414 46.6 4.83 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 6.03 1 0 4 31 4.338E8 24.57 6.03 4 15 1809.08 6.03 4 16 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 6.03 1 0 4 31 4.338E8 24.57 6.03 4 15 1809.08 6.03 4 16 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 6.03 1 0 4 31 4.338E8 24.57 6.03 4 15 1809.08 6.03 4 16 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 6.03 1 0 4 31 4.338E8 24.57 6.03 4 15 1809.08 6.03 4 16 564 60.0 7.72 HVO_1725 Orc1-type DNA replication protein 5.99 1 2 2 3 5.693E7 1.86 5.99 2 3 401 44.5 5.19 HVO_A0328 2-keto-3-deoxygluconate kinase 5.97 1 1 2 4 1.255E8 1.65 5.97 2 2 210.43 5.97 2 2 318 34.0 4.60 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 5.88 1 2 2 6 1.448E8 7.18 5.88 2 3 371.56 5.88 2 3 459 50.5 4.63 HVO_2812 AstE family protein 5.87 1 2 2 4 6.670E7 0.00 5.87 2 2 114.99 5.87 2 2 341 37.3 5.14 HVO_3000 DNA ligase (NAD) 5.87 1 3 3 7 6.546E8 6.08 3.86 2 3 354.50 5.87 3 4 699 75.8 4.50 HVO_2873 flap endonuclease Fen1 5.83 1 2 2 2 2.477E7 1.68 5.83 2 2 326 36.4 4.40 HVO_0710 aminodeoxychorismate synthase component II 5.75 1 2 2 4 1.354E8 0.00 5.75 2 2 117.23 5.75 2 2 504 54.6 4.53 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 5.72 1 0 3 22 4.754E8 18.33 5.72 3 11 1390.11 5.72 3 11 472 51.6 5.16 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 5.71 1 0 3 22 4.754E8 18.33 5.71 3 11 1390.11 5.71 3 11 473 51.2 5.05 HVO_1710 alpha amylase 5.47 1 4 4 14 1.136E8 6.29 5.47 4 7 616.01 5.47 4 7 677 75.0 4.45 HVO_1052 transcription initiation factor TFB 5.42 1 0 2 2 2.412E8 114.64 5.42 2 2 332 37.3 5.25 HVO_C0043 conserved hypothetical protein 5.30 1 3 3 4 3.303E7 0.00 4.08 2 2 114.80 3.93 2 2 661 73.8 4.75 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 5.24 1 1 2 2 5.158E7 2.66 5.24 2 2 573 62.9 4.45 HVO_B0285 transcription initiation factor TFB 5.23 1 0 2 2 2.412E8 114.64 5.23 2 2 344 38.4 5.14 HVO_0670 glutathione S-transferase 5.21 1 2 2 2 7.234E7 117.70 5.21 2 2 326 38.1 4.56 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 5.14 1 3 3 3 6.831E7 4.45 5.14 3 3 740 85.6 4.70 HVO_B0233 alpha-L-arabinofuranosidase 5.09 1 2 2 2 1.732E8 147.24 5.09 2 2 511 57.5 4.39 HVO_2321 bacterial-type DNA primase DnaG 4.87 1 2 2 7 1.045E8 1.85 4.87 2 3 284.15 4.87 2 4 472 49.4 4.36 HVO_1867 lysine--tRNA ligase 4.86 1 3 3 12 2.782E8 9.26 4.86 3 6 600.97 4.86 3 6 555 62.1 4.46 HVO_1340 "probable glycosyltransferase, type 1" 4.80 1 2 2 6 6.221E7 0.00 4.80 2 3 202.39 4.80 2 3 375 41.0 4.42 4504911 keratin 13 isoform b [Homo sapiens] 4.76 1 0 2 4 1.595E7 589.66 4.76 2 4 420 45.8 4.88 27894337 keratin 20 [Homo sapiens] 4.72 1 1 2 4 8.469E7 9.56 4.72 2 4 424 48.5 5.69 HVO_0014 ATP-dependent DNA helicase Hel308a 4.59 1 3 3 9 8.260E7 3.70 3.51 2 4 362.84 4.59 3 5 827 90.3 4.67 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 4.41 1 3 3 4 5.385E7 1.89 3.04 2 2 100.74 3.04 2 2 658 72.1 4.70 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 4.37 1 0 2 4 1.595E7 589.66 4.37 2 4 458 49.6 4.96 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 4.30 1 2 2 6 1.330E8 2.02 4.30 2 3 205.32 4.30 2 3 838 89.1 4.65 386849 keratin type II 4.26 1 0 2 8 3.789E8 8.96 4.26 2 4 550.75 4.26 2 4 563 59.9 7.94 HVO_2004 serine O-acetyltransferase 4.18 1 1 2 11 5.735E8 0.00 4.18 2 5 416.34 4.18 2 6 287 31.9 5.21 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 4.17 1 0 2 8 5.245E8 10.04 4.17 2 4 662.68 4.17 2 4 432 48.1 5.02 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 4.05 1 1 2 4 1.016E9 0.00 4.05 2 4 444 47.1 4.77 HVO_B0143 receiver/sensor box histidine kinase 4.02 1 2 2 6 9.682E7 6.46 4.02 2 3 363.11 4.02 2 3 597 66.0 4.41 HVO_2888 homolog to elongator complex protein ELP3 4.00 1 2 2 6 2.006E7 0.00 4.00 2 3 231.75 4.00 2 3 550 62.6 5.01 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 4.00 1 0 2 2 5.106E8 166.10 4.00 2 2 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 4.00 1 0 2 2 5.106E8 166.10 4.00 2 2 400 44.1 5.14 HVO_1625 conserved hypothetical protein 3.98 1 2 2 6 1.994E8 7.50 3.98 2 3 376.44 3.98 2 3 654 70.1 4.04 HVO_2955 DEAD/DEAH box helicase 3.98 1 2 2 2 9.711E7 150.33 3.98 2 2 779 85.8 4.94 31074633 keratin 6L [Homo sapiens] 3.93 1 0 2 3 3.647E8 363.74 3.93 2 3 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 3.93 1 0 2 3 3.647E8 363.74 3.93 2 3 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 3.93 1 0 2 3 3.647E8 363.74 3.93 2 3 535 57.7 7.20 HVO_A0156 acyl-CoA synthetase 3.92 1 0 2 6 2.186E8 6.92 3.92 2 3 302.57 3.92 2 3 664 74.0 4.40 31074631 keratin 1b [Homo sapiens] 3.46 1 0 2 21 1.214E9 14.43 3.46 2 10 1235.70 3.46 2 11 578 61.8 5.97 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 3.37 1 4 4 8 2.966E7 3.28 3.37 4 5 277.98 1.35 2 3 1335 150.5 4.60 HVO_2183 aldehyde ferredoxin oxidoreductase 2.64 1 2 2 2 3.290E7 170.09 2.64 2 2 643 69.3 4.59 HVO_B0154 receiver/sensor box histidine kinase 2.46 1 3 3 7 1.374E7 3.89 1.77 2 3 282.17 2.46 3 4 1301 144.1 4.39 HVO_0220 ATP-dependent DNA helicase MCM 2.14 1 2 2 3 9.654E7 289.16 2.14 2 3 702 78.8 4.73 4504919 keratin 8 [Homo sapiens] 2.07 1 0 2 23 3.247E8 15.61 2.07 2 11 1258.33 2.07 2 12 483 53.7 5.59 HVO_0689 chromosome segregation protein Smc 1.77 1 3 3 5 1.315E8 0.00 1.29 2 2 259.12 1.77 3 3 1240 138.1 4.39