Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0359 translation elongation factor aEF-1 alpha subunit 79.57 1 20 24 1198 8.793E10 1135.30 79.57 22 552 91134.30 79.57 24 646 421 45.7 4.73 HVO_0880 conserved hypothetical protein 78.83 1 29 29 336 6.594E9 379.54 78.83 28 165 24015.61 78.83 29 171 307 36.3 4.74 HVO_0356 translation elongation factor aEF-2 74.28 1 43 43 967 3.063E10 872.82 73.45 42 479 54164.26 74.28 43 488 727 80.4 4.73 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 70.29 1 18 18 330 1.873E10 287.40 70.29 18 166 21350.93 70.29 18 164 350 37.6 4.54 HVO_2544 30S ribosomal protein S5 69.63 1 13 13 80 1.120E10 45.73 61.68 11 40 4466.70 67.29 12 40 214 23.3 9.29 HVO_1507 acetolactate synthase small subunit 66.97 1 11 11 60 1.309E9 61.65 66.97 11 30 4097.18 66.97 11 30 218 23.7 4.94 HVO_1273 inosine-5'-monophosphate dehydrogenase 66.87 1 22 22 217 7.667E9 183.70 61.24 20 106 12815.99 66.87 22 111 498 53.3 4.55 HVO_0175 DNA polymerase sliding clamp 64.78 1 10 10 165 5.647E9 115.98 64.78 10 82 8345.48 64.78 10 83 247 26.7 4.39 HVO_0677 aspartate--tRNA ligase 63.36 1 19 19 290 1.045E10 282.58 63.36 19 144 17151.28 62.21 18 146 434 48.7 4.50 HVO_0239 glutamine synthetase 63.16 1 21 21 165 1.084E10 121.73 51.97 17 79 9772.09 63.16 21 86 456 50.5 4.56 HVO_1921 serine--tRNA ligase 62.61 1 23 23 125 2.845E9 104.80 62.61 23 62 7657.23 62.61 23 63 460 52.0 4.46 HVO_2900 fumarate hydratase 62.05 1 17 17 163 8.394E9 178.70 62.05 17 82 10318.06 62.05 17 81 469 50.1 4.78 HVO_0025 thiosulfate sulfurtransferase 61.89 1 11 11 375 1.721E10 311.27 59.44 10 188 19494.93 61.89 11 187 286 32.1 4.28 HVO_0055 CBS domain protein 61.62 1 12 12 95 4.879E9 98.28 61.62 12 47 6636.66 61.62 12 48 284 30.8 4.27 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 61.34 1 6 6 53 2.962E9 43.78 50.52 5 19 4728.10 61.34 6 34 194 20.7 4.12 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 60.50 1 13 13 72 2.547E9 57.29 60.50 13 34 4048.77 60.50 13 38 281 30.6 4.59 HVO_0329 branched-chain amino acid aminotransferase 59.94 1 15 15 118 4.901E9 123.60 59.94 15 58 8455.49 59.94 15 60 312 35.0 4.58 HVO_2862 serine hydroxymethyltransferase 59.52 1 16 16 308 1.202E10 246.98 55.42 14 151 17517.63 59.52 16 157 415 44.3 4.53 HVO_1637 FKBP-type peptidylprolyl isomerase 59.48 1 11 12 116 6.883E9 82.38 28.10 9 54 7685.62 59.48 12 62 306 33.8 3.76 HVO_2783 30S ribosomal protein S4 59.43 1 11 11 74 4.875E9 55.27 59.43 11 36 4765.01 59.43 11 38 175 20.1 5.24 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 59.32 1 15 15 199 1.218E10 139.82 59.32 15 98 10512.09 59.32 15 101 381 41.0 4.23 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 58.01 1 12 12 275 1.233E10 238.40 58.01 12 141 15041.64 58.01 12 134 312 34.5 4.98 HVO_2913 superoxide dismutase (Mn) 57.79 1 0 5 51 1.034E10 68.01 57.79 5 25 3811.99 57.79 5 26 199 22.3 4.48 HVO_0861 SufB domain protein 57.71 1 16 16 167 6.889E9 165.74 57.71 16 82 12040.21 57.71 16 85 402 44.7 4.23 HVO_2588 isocitrate dehydrogenase (NADP) 57.52 1 23 23 199 1.472E10 209.04 52.74 21 98 13707.03 57.52 23 101 419 45.8 4.59 HVO_A0475 superoxide dismutase (Mn) 57.50 1 0 5 51 1.034E10 68.01 57.50 5 25 3811.99 57.50 5 26 200 22.4 4.45 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 57.34 1 11 11 45 1.371E9 33.84 57.34 10 22 2258.35 51.40 10 23 286 31.2 4.54 HVO_1454 aspartate carbamoyltransferase catalytic subunit 56.91 1 9 9 25 6.575E8 18.19 56.91 9 12 1239.22 43.75 8 13 304 33.7 4.92 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 56.77 1 15 15 149 7.718E9 189.44 56.77 15 75 11745.17 56.77 15 74 384 41.4 4.41 HVO_1082 homolog to orotate phosphoribosyltransferase 56.67 1 9 9 57 1.653E9 45.78 46.67 8 28 3459.18 56.67 9 29 210 22.3 4.42 HVO_0859 FeS assembly ATPase SufC 56.48 1 15 15 160 6.306E9 94.02 54.49 14 78 8826.78 56.48 15 82 301 33.4 4.35 HVO_2968 phosphoglycerate dehydrogenase 56.19 1 19 19 202 1.163E10 220.54 56.19 19 102 14721.74 56.19 19 100 525 55.3 4.36 HVO_0104 DNA repair and recombination protein RadA 55.98 1 14 14 80 4.562E9 64.34 48.98 12 36 5967.45 43.73 13 44 343 37.3 4.64 HVO_0348 DNA-directed RNA polymerase subunit B' 55.34 1 25 25 174 3.016E9 151.74 55.34 25 86 9959.08 49.75 24 88 609 67.7 4.92 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 55.31 1 10 10 39 8.931E8 32.24 55.31 10 20 2343.37 52.21 9 19 226 25.5 4.25 HVO_0581 "cell division protein FtsZ, type II" 55.00 1 15 15 84 2.954E9 86.71 55.00 15 43 5418.05 47.75 14 41 400 42.5 4.75 HVO_0778 thermosome subunit 3 52.67 1 19 21 148 2.603E9 147.87 49.62 19 73 9738.22 52.67 21 75 524 55.2 4.59 HVO_0729 inorganic pyrophosphatase 52.54 1 9 9 59 3.701E9 62.33 52.54 9 30 3975.47 52.54 9 29 177 20.4 4.16 HVO_0870 proline--tRNA ligase 52.46 1 17 17 94 2.685E9 72.48 50.00 16 46 6072.58 49.59 16 48 488 54.9 4.44 HVO_0317 A-type ATP synthase subunit B 52.35 1 14 15 168 1.230E10 192.92 52.35 15 81 12892.91 52.35 15 87 468 51.9 4.25 HVO_2724 beta-lactamase domain protein 52.22 1 18 18 197 7.710E9 164.36 52.22 18 99 11000.44 51.56 17 98 450 50.1 5.40 HVO_0850 proteasome-activating nucleotidase 51.85 1 13 14 68 1.844E9 43.63 46.67 13 30 3560.57 51.85 14 38 405 45.6 4.60 HVO_0133 thermosome subunit 1 51.61 1 18 20 144 5.430E9 145.16 47.14 19 72 9835.97 50.36 19 72 560 58.9 4.25 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 51.31 1 12 12 52 1.068E9 45.08 51.31 12 26 3343.62 51.31 12 26 343 38.4 4.94 HVO_1502 3-isopropylmalate dehydrogenase 50.93 1 13 13 97 5.598E9 93.48 43.21 12 44 7056.39 50.93 13 53 324 33.7 4.23 HVO_2621 phosphoenolpyruvate carboxylase 50.28 1 34 35 178 4.545E9 128.36 48.38 32 89 9025.26 47.38 33 89 897 102.3 4.64 HVO_0869 glutamate synthase large subunit 50.23 1 56 56 308 3.692E9 289.23 49.70 55 151 19946.70 50.23 55 157 1511 163.8 4.70 HVO_0860 SufB domain protein 50.21 1 19 19 181 9.341E9 141.91 45.38 16 87 10977.64 50.21 19 94 476 53.2 4.69 HVO_2969 threonine synthase 50.12 1 16 16 82 3.298E9 59.48 48.45 15 40 4818.90 50.12 16 42 419 44.4 4.49 HVO_1132 adenylosuccinate synthase 50.11 1 20 20 283 1.093E10 217.89 46.95 19 138 15775.10 50.11 20 145 443 48.2 4.56 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 50.00 1 19 19 119 4.625E9 109.50 50.00 19 59 7456.90 49.16 18 60 592 66.6 4.61 HVO_1133 conserved hypothetical protein 49.50 1 3 3 14 6.317E8 13.45 49.50 3 7 691.56 49.50 3 7 101 11.7 4.58 HVO_2889 RecJ domain protein 49.25 1 27 28 222 9.816E9 201.52 49.25 28 110 14395.35 49.25 28 112 729 79.1 4.37 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 49.21 1 12 12 38 1.226E9 30.47 49.21 12 20 1734.73 40.22 10 18 445 47.8 4.86 HVO_1145 30S ribosomal protein S1e 49.09 1 11 11 65 2.485E9 68.20 46.36 10 31 4568.60 49.09 11 34 220 24.8 4.86 HVO_0347 DNA-directed RNA polymerase subunit B'' 48.94 1 22 22 123 2.992E9 89.08 48.94 22 59 6755.89 48.94 22 64 521 58.9 5.00 HVO_0789 tryptophan synthase alpha subunit 48.74 1 8 8 40 6.899E8 36.37 48.74 8 19 2321.87 45.85 7 21 277 29.6 4.21 HVO_0240 Lrp/AsnC family transcription regulator 48.03 1 5 6 32 1.763E9 22.62 48.03 6 15 1547.54 48.03 6 17 152 16.9 4.39 HVO_0314 A-type ATP synthase subunit C 47.99 1 14 14 66 1.430E9 58.36 43.97 13 31 4095.06 47.99 14 35 348 38.7 4.50 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 47.89 1 6 6 42 2.593E9 36.58 47.89 6 21 2965.80 47.89 6 21 190 20.6 4.30 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 47.76 1 4 4 11 1.799E8 5.04 41.04 3 4 797.79 47.76 4 7 134 13.9 4.55 HVO_1541 glycerol kinase 47.65 1 19 20 146 6.983E9 117.39 43.33 18 69 9450.24 47.65 20 77 510 56.7 4.50 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 47.64 1 7 7 27 6.974E8 12.88 30.31 5 12 1327.46 47.64 7 15 254 26.9 4.42 HVO_2646 dihydroxy-acid dehydratase 47.26 1 19 19 154 3.875E9 128.72 47.26 19 77 8701.76 47.26 18 77 584 61.8 4.42 HVO_2558 30S ribosomal protein S3 47.04 1 13 13 171 9.575E9 163.05 42.76 12 80 13717.19 47.04 13 91 304 33.4 4.06 HVO_1506 ketol-acid reductoisomerase 46.84 1 11 11 124 2.303E9 99.95 46.84 11 62 6798.43 46.84 10 62 348 37.9 4.34 HVO_1284 GTP cyclohydrolase III 46.74 1 8 8 32 3.669E8 27.85 46.74 8 16 1881.67 36.78 7 16 261 28.9 4.70 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 46.59 1 22 22 350 2.606E10 366.60 46.59 20 170 25673.32 46.59 22 180 631 68.4 4.49 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 165 5.358E9 164.90 43.25 7 81 10693.46 46.37 8 84 289 29.8 4.27 HVO_2756 50S ribosomal protein L10 46.26 1 9 9 40 2.967E9 33.47 39.94 8 21 2601.70 44.25 8 19 348 36.9 3.99 HVO_1590 DnaK-type molecular chaperone Hsp70 45.92 1 24 24 192 6.937E9 175.83 43.68 22 95 12240.04 45.92 24 97 625 67.2 4.18 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 45.90 1 12 12 63 4.349E9 52.65 40.98 11 28 4139.69 45.90 12 35 305 33.8 4.74 HVO_1084 adenylosuccinate lyase 45.79 1 16 16 47 9.993E8 32.09 44.71 15 25 2234.66 34.13 14 22 463 50.8 4.70 HVO_0024 thiosulfate sulfurtransferase 45.74 1 8 8 43 1.743E9 27.94 36.05 6 20 2371.71 45.74 8 23 258 28.4 4.30 HVO_0806 pyruvate kinase 45.64 1 19 19 107 4.704E9 94.41 45.64 19 53 6511.89 41.54 18 54 585 62.0 4.54 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 45.54 1 9 9 118 1.443E9 107.24 40.18 8 57 7019.36 45.54 9 61 336 36.8 4.12 HVO_1481 UspA domain protein 45.40 1 6 6 40 2.817E9 31.64 45.40 6 20 2452.59 45.40 6 20 163 17.7 4.40 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 45.35 1 10 10 44 2.025E9 26.26 41.69 9 22 2231.51 45.35 10 22 355 38.2 4.68 HVO_1300 triosephosphate isomerase 45.33 1 6 6 49 5.492E9 48.26 45.33 6 24 3368.02 45.33 6 25 214 21.3 4.26 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 45.26 1 10 10 35 9.790E8 18.65 45.26 10 17 1654.50 35.07 9 18 422 43.6 4.72 HVO_0455 thermosome subunit 2 45.24 1 20 21 190 4.644E9 145.96 45.24 21 90 9823.95 45.24 21 100 557 59.3 4.37 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 45.21 1 6 6 47 2.345E9 34.67 45.21 6 23 2416.79 45.21 6 24 188 20.5 4.60 HVO_A0207 CRISPR-associated protein Cas7 44.71 1 8 8 50 1.252E9 44.43 44.71 8 25 2892.80 44.71 8 25 340 38.2 4.54 HVO_1955 aconitate hydratase 44.50 1 23 23 303 1.264E10 293.57 43.73 22 153 20359.85 44.50 23 150 654 70.4 4.45 HVO_0316 A-type ATP synthase subunit A 44.20 1 20 20 167 6.813E9 153.10 44.20 20 83 10647.62 44.20 19 84 586 64.5 4.25 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 43.62 1 16 16 94 3.414E9 94.55 41.71 15 44 6639.42 43.62 15 50 525 56.4 4.40 HVO_2413 translation elongation factor aEF-1 alpha subunit 43.57 1 12 17 114 1.471E10 73.66 42.14 14 55 6309.44 43.33 16 59 420 45.6 4.75 HVO_0212 homolog to lactoylglutathione lyase 43.55 1 3 3 14 1.023E9 17.53 43.55 3 7 646.37 43.55 3 7 124 13.5 4.13 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 43.21 1 8 8 96 3.838E9 81.73 41.46 7 48 6218.82 43.21 8 48 287 31.0 4.73 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 42.94 1 16 16 74 1.944E9 55.72 40.12 14 35 3763.13 42.94 16 39 496 55.0 4.53 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 42.92 1 12 12 53 6.061E8 40.00 29.60 9 25 2421.88 36.15 11 28 473 50.8 4.58 HVO_0203 replication factor C small subunit 42.81 1 11 11 50 8.409E8 30.78 42.81 11 25 2250.50 42.81 11 25 327 36.2 4.51 HVO_2191 formyltetrahydrofolate deformylase 42.81 1 10 10 55 2.951E9 50.57 42.81 10 27 3630.17 42.81 10 28 327 36.2 4.63 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 42.76 1 8 8 53 3.722E9 52.34 38.05 7 27 3196.70 42.76 8 26 297 31.3 4.36 HVO_2487 aspartate-semialdehyde dehydrogenase 42.73 1 8 8 80 6.028E9 50.91 42.73 8 40 3857.21 42.73 8 40 344 36.6 4.41 HVO_1545 dihydroxyacetone kinase subunit DhaL 42.67 1 8 8 56 3.817E9 46.54 42.67 8 27 3442.43 42.67 8 29 232 24.8 4.48 HVO_2384 CBS domain protein 42.37 1 14 15 74 4.673E9 54.88 41.05 14 37 4187.47 38.42 13 37 380 42.5 5.01 HVO_0792 3-dehydroquinate synthase type II 42.35 1 12 12 49 1.193E9 43.94 42.35 12 25 2967.82 42.35 12 24 392 43.1 4.44 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.11 1 9 9 57 2.108E9 45.55 42.11 9 29 3707.80 42.11 9 28 266 27.8 4.84 HVO_2981 uracil phosphoribosyltransferase 42.04 1 6 6 20 2.817E9 7.30 34.51 5 8 902.77 42.04 6 12 226 24.5 4.49 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 41.98 1 18 18 202 5.742E9 174.63 40.61 17 97 12558.59 41.98 18 105 586 64.0 4.49 HVO_0310 A-type ATP synthase subunit H 41.82 1 2 2 4 2.971E8 2.03 41.82 2 2 99.16 41.82 2 2 110 12.5 4.03 HVO_0999 DRTGG domain protein 41.80 1 11 11 67 1.987E9 47.54 41.80 11 33 3490.32 41.80 11 34 378 39.8 4.44 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 41.76 1 11 11 49 7.484E8 37.61 41.76 11 24 2319.27 40.00 10 25 340 38.8 4.58 HVO_2057 sugar nucleotidyltransferase 41.74 1 11 11 48 2.013E9 39.47 41.74 11 24 2654.10 36.69 10 24 357 37.8 4.44 HVO_1189 aldehyde dehydrogenase 41.73 1 15 15 84 4.520E9 77.72 34.45 14 41 5549.39 41.73 15 43 508 56.1 4.59 HVO_2015 conserved hypothetical protein 41.45 1 10 10 168 1.782E10 172.74 41.45 10 84 11811.66 41.45 10 84 345 37.7 4.25 HVO_2552 30S ribosomal protein S4e 41.30 1 8 8 146 2.042E10 148.40 41.30 8 72 8478.13 41.30 8 74 247 26.6 4.58 HVO_A0205 CRISPR-associated endoribonuclease Cas6 41.18 1 10 10 50 7.303E8 31.05 41.18 10 25 2936.05 41.18 10 25 272 31.0 5.44 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 40.93 1 11 11 72 2.513E9 46.50 37.07 10 35 4291.43 40.93 11 37 259 29.9 4.36 HVO_0046 putative glutamate--argW ligase 40.89 1 9 9 55 2.216E9 54.34 33.68 8 26 3669.04 40.89 9 29 291 31.9 4.87 HVO_0109 cysteine desulfurase 40.85 1 13 13 41 1.060E9 36.47 36.15 11 20 2783.13 37.79 12 21 426 46.8 4.56 HVO_1504 3-isopropylmalate dehydratase large subunit 40.80 1 16 17 137 8.133E9 141.20 39.11 16 69 10074.90 39.75 16 68 473 51.6 4.55 HVO_0480 phosphoglycerate kinase 40.40 1 13 13 62 2.753E9 59.98 38.65 12 30 3943.23 40.40 13 32 401 43.6 4.37 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 40.30 1 8 8 33 7.110E8 33.78 40.30 8 17 1975.73 40.30 8 16 330 36.3 4.35 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 59 2.120E9 64.17 40.26 5 31 4329.29 40.26 5 28 154 17.5 4.50 HVO_2204 "FtsZ family protein, type III" 40.25 1 11 13 68 3.442E9 68.41 36.46 12 33 4845.76 40.25 13 35 395 42.0 4.68 HVO_0433 F420H2:NADP oxidoreductase 39.64 1 6 6 36 2.219E9 36.32 39.64 6 18 2374.96 39.64 6 18 222 23.3 4.72 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 39.61 1 12 13 64 1.794E9 45.73 37.42 12 31 3068.11 39.17 12 33 457 48.4 4.35 HVO_0353 30S ribosomal protein S12 39.44 1 7 7 34 1.649E9 32.57 39.44 7 16 1913.45 39.44 7 18 142 15.5 9.91 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 39.44 1 9 9 51 1.994E9 42.32 39.44 9 25 2842.18 39.44 9 26 360 39.6 4.39 HVO_1198 UspA domain protein 39.31 1 5 5 16 1.164E9 17.24 39.31 5 8 1025.95 39.31 5 8 145 15.6 4.75 HVO_1091 proteasome alpha subunit 39.29 1 9 10 64 3.625E9 60.49 39.29 10 32 4452.36 39.29 10 32 252 27.6 4.56 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 39.23 1 10 10 66 5.934E9 54.01 31.96 9 32 3945.06 39.23 10 34 413 45.8 4.45 HVO_2029 Lrp/AsnC family transcription regulator 39.22 1 3 4 26 1.720E9 15.08 26.80 3 11 1218.35 39.22 4 15 153 16.9 4.21 HVO_0809 methionine--tRNA ligase 39.19 1 20 20 97 1.642E9 63.33 39.19 20 48 4753.57 39.19 20 49 740 81.9 4.37 HVO_1370 gamma-glutamyl phosphate reductase 39.19 1 14 14 70 2.008E9 45.32 39.19 14 36 3223.72 39.19 14 34 444 48.1 4.34 HVO_1031 thioredoxin-disulfide reductase 39.18 1 9 9 33 7.396E8 27.62 39.18 9 17 1697.81 37.43 8 16 342 37.4 4.46 HVO_0161 ATP phosphoribosyltransferase 39.15 1 8 8 31 8.653E8 27.68 39.15 8 15 1799.92 39.15 8 16 281 30.4 4.60 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 39.03 1 11 11 39 1.616E9 34.77 35.02 10 19 2603.11 39.03 11 20 474 53.4 4.59 HVO_1684 threonine--tRNA ligase 38.88 1 23 23 136 3.287E9 130.84 38.88 23 69 8799.64 37.95 22 67 643 73.4 4.45 HVO_0889 FAD-dependent oxidoreductase 38.79 1 3 3 5 7.501E7 2.67 19.63 2 2 276.90 38.79 3 3 214 21.8 3.89 HVO_0602 3-dehydroquinate dehydratase 38.46 1 6 6 26 3.076E8 13.04 38.46 6 12 1247.15 38.46 6 14 247 27.3 4.51 HVO_1858 30S ribosomal protein S19e 38.41 1 3 3 8 7.642E7 0.00 26.49 2 3 333.09 38.41 3 5 151 16.7 4.84 HVO_0694 probable phosphoribosyltransferase 38.40 1 9 9 33 3.664E8 24.48 38.40 9 17 1581.48 35.86 8 16 237 27.0 4.32 HVO_2774 enolase 38.35 1 10 10 67 5.329E9 61.80 38.35 10 34 3773.98 38.35 10 33 399 42.0 4.37 HVO_1125 cysteine--tRNA ligase 38.26 1 13 13 65 1.279E9 54.69 38.26 13 33 3610.22 35.63 12 32 494 55.2 4.56 HVO_0536 ferritin 38.07 1 3 3 17 1.097E9 14.07 38.07 3 8 727.37 38.07 3 9 176 19.9 4.50 HVO_2419 hydroxymethylglutaryl-CoA synthase 37.98 1 13 13 64 1.936E9 54.50 37.98 13 32 2946.44 37.98 13 32 445 50.1 4.64 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.95 1 10 10 55 4.221E9 42.63 37.95 10 28 2950.75 37.95 10 27 332 34.8 4.22 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 37.95 1 32 32 190 1.755E9 141.37 32.24 29 92 10395.28 37.95 32 98 1033 114.3 4.45 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 37.84 1 7 7 45 2.058E9 38.14 37.84 7 22 2626.36 37.84 7 23 259 28.0 4.50 HVO_1973 conserved hypothetical protein 37.72 1 3 3 19 3.537E8 16.09 37.72 3 9 981.72 37.72 3 10 167 18.1 4.36 HVO_2555 30S ribosomal protein S17 37.72 1 2 2 4 3.513E7 2.13 37.72 2 2 162.22 37.72 2 2 114 12.7 4.81 HVO_0324 arginine--tRNA ligase 37.65 1 19 19 84 2.326E9 84.44 37.65 19 43 5174.69 34.75 16 41 587 65.0 4.35 HVO_2726 glutamate--tRNA ligase 37.61 1 15 15 77 1.390E9 56.01 37.61 15 39 3984.35 37.61 15 38 585 65.2 4.58 HVO_2790 ATP-binding protein Mrp 37.57 1 8 8 27 4.593E8 20.83 37.57 8 14 1291.27 37.57 8 13 346 36.8 4.50 HVO_A0496 UspA domain protein 37.24 1 8 8 21 7.273E8 15.09 26.90 7 10 1048.35 37.24 8 11 290 31.4 4.60 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 37.22 1 15 15 58 1.366E9 45.78 37.22 15 30 2829.42 37.22 15 28 626 67.6 4.65 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 37.14 1 9 9 48 2.965E9 42.72 37.14 9 25 2896.83 37.14 9 23 280 30.1 4.44 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 37.13 1 6 6 32 6.890E8 14.48 37.13 6 16 1540.28 37.13 6 16 202 22.2 5.11 HVO_0788 tryptophan synthase beta subunit 36.73 1 10 10 50 1.546E9 49.28 25.36 8 24 2827.29 36.73 10 26 422 45.7 4.65 HVO_0313 A-type ATP synthase subunit E 36.60 1 5 5 30 9.659E8 26.37 26.29 3 12 2145.44 36.60 5 18 194 22.0 4.31 HVO_3007 malate dehydrogenase 36.51 1 11 11 216 8.654E9 236.99 36.51 11 107 12472.59 36.51 11 109 304 32.6 4.40 HVO_0980 NADH dehydrogenase-like complex subunit CD 36.45 1 12 15 59 2.034E9 39.53 36.45 15 30 2847.62 36.45 15 29 557 63.4 4.53 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 36.43 1 8 8 59 2.215E9 61.45 33.87 7 28 4296.02 36.43 8 31 431 46.1 4.48 HVO_2813 RimK family protein 36.20 1 13 13 81 3.637E9 66.90 34.00 12 39 5103.69 36.20 13 42 453 49.0 4.73 HVO_2773 30S ribosomal protein S2 36.15 1 5 5 64 7.367E9 69.03 36.15 5 31 5079.78 36.15 5 33 260 28.3 4.16 HVO_0138 tyrosine--tRNA ligase 35.98 1 7 7 36 1.236E9 24.56 25.00 6 17 1858.64 35.98 7 19 328 36.1 4.34 HVO_1577 conserved hypothetical protein 35.59 1 5 5 16 1.053E9 16.46 35.59 5 8 1146.57 35.59 5 8 177 19.4 4.74 HVO_A0206 CRISPR-associated protein Cas8b 35.56 1 18 18 71 1.325E9 55.96 35.56 18 37 3328.40 31.10 16 34 717 79.3 4.60 HVO_0511 NAD-dependent epimerase/dehydratase 35.50 1 6 6 22 4.417E8 19.60 35.50 6 12 1317.14 20.61 4 10 262 29.3 4.78 HVO_0008 aspartate kinase 35.46 1 9 9 62 5.437E9 36.12 33.67 8 30 3118.25 35.46 9 32 392 41.7 4.46 HVO_2519 conserved hypothetical protein 35.34 1 10 10 47 1.272E9 38.85 30.63 9 22 3007.09 35.34 10 25 382 40.7 4.35 HVO_2153 probable copper-containing oxidoreductase 35.06 1 8 8 29 3.640E8 32.91 35.06 8 15 1936.45 25.71 7 14 385 42.1 5.82 HVO_1212 KaiC-type circadian regulator CirA 34.55 1 8 8 48 2.502E9 50.87 34.55 8 23 3635.97 34.55 8 25 246 27.5 4.45 HVO_0743 probable phosphodiesterase 34.52 1 18 18 103 2.697E9 75.77 34.52 18 51 5424.92 33.18 17 52 449 50.5 4.56 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 34.45 1 5 5 10 4.432E8 4.18 25.21 4 5 346.50 23.53 4 5 238 24.7 4.15 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 34.44 1 9 9 42 2.710E8 36.74 34.44 9 20 2467.23 34.44 9 22 363 39.3 4.97 HVO_0424 ABC-type transport system ATP-binding protein 34.44 1 16 16 65 8.567E8 66.72 32.45 15 32 3938.75 34.44 16 33 604 67.2 4.49 HVO_0449 prephenate dehydratase 34.33 1 7 7 28 5.978E8 28.40 34.33 7 14 1623.83 34.33 7 14 268 28.7 4.64 HVO_0049 argininosuccinate synthase 34.32 1 12 12 83 4.336E9 54.88 34.32 12 42 4783.74 34.32 12 41 405 44.5 4.34 HVO_2225 AstE family protein 34.31 1 6 6 15 5.778E8 11.01 24.34 5 7 757.18 26.39 5 8 341 36.9 4.53 HVO_2059 NAD-dependent epimerase/dehydratase 34.19 1 7 7 42 1.140E9 23.56 34.19 7 22 1974.56 34.19 7 20 310 34.1 4.40 HVO_1562 proteasome beta subunit 34.16 1 6 6 45 1.115E9 32.13 34.16 6 23 2118.36 34.16 6 22 243 26.0 4.63 HVO_1306 chorismate synthase 34.03 1 9 9 43 6.461E8 34.67 34.03 9 22 1963.35 34.03 9 21 385 41.9 4.83 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 33.91 1 13 13 53 9.886E8 50.76 33.62 12 25 3440.28 33.91 13 28 348 38.2 4.32 HVO_0717 "cell division protein FtsZ, type I" 33.77 1 10 10 70 6.375E9 63.45 33.77 10 32 5008.50 33.77 10 38 379 39.8 4.40 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 33.63 1 10 10 34 9.722E8 22.51 33.63 10 17 1471.55 33.63 10 17 336 38.0 4.61 HVO_2706 translation initiation factor aIF-2B delta subunit 32.98 1 6 6 17 4.855E8 15.55 29.79 5 8 892.60 32.98 6 9 282 30.7 4.42 HVO_A0636 YbaK domain protein 32.91 1 3 3 18 1.913E8 14.09 32.91 3 9 890.68 32.91 3 9 158 16.7 4.54 HVO_1901 translation initiation factor aIF-2 gamma subunit 32.85 1 10 10 78 2.949E9 63.75 32.85 10 36 4333.70 30.66 9 42 411 43.9 4.36 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 32.81 1 12 12 68 2.642E9 69.09 32.81 12 35 4311.07 32.81 12 33 512 53.8 4.78 HVO_1123 thioredoxin-disulfide reductase 32.66 1 8 8 41 1.777E9 17.35 27.79 6 18 1898.28 32.66 8 23 349 37.3 4.32 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 32.61 1 5 5 19 3.904E8 11.02 27.17 4 8 1001.85 32.61 5 11 184 19.8 5.30 HVO_2548 50S ribosomal protein L6 32.58 1 3 3 7 9.679E7 6.90 32.58 3 7 178 19.6 4.68 HVO_2222 CYPL-type peptidylprolyl isomerase 32.56 1 3 3 8 4.252E7 0.00 25.58 2 4 384.75 32.56 3 4 172 18.7 4.44 HVO_0393 UvrABC system protein A 32.55 1 25 25 85 5.478E8 60.79 27.77 23 41 4108.35 32.55 25 44 983 108.6 4.82 HVO_2624 CTP synthase 32.42 1 13 13 55 2.070E9 45.80 30.78 12 27 2992.71 32.42 13 28 549 60.8 4.70 HVO_2700 AAA-type ATPase (CDC48 subfamily) 32.36 1 20 21 65 7.136E8 36.60 31.03 20 33 2760.16 32.36 21 32 754 82.8 4.75 HVO_B0118 SMC-like protein Sph2 32.30 1 19 19 115 2.963E9 102.26 31.21 18 57 7043.07 32.30 19 58 644 73.8 4.41 HVO_1965 rRNA maturation endonuclease Nob1 32.24 1 2 2 2 3.924E8 58.63 32.24 2 2 152 16.8 4.70 HVO_1854 histidine--tRNA ligase 32.02 1 10 10 54 8.347E8 54.52 32.02 10 26 3835.52 32.02 10 28 431 47.1 4.37 HVO_2861 conserved hypothetical protein 32.00 1 8 8 44 1.354E9 49.25 32.00 8 22 2679.77 32.00 8 22 275 29.1 4.27 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 31.94 1 10 10 33 2.202E8 26.56 30.62 9 16 1603.53 29.74 9 17 454 48.5 4.46 HVO_1391 NUDIX family hydrolase 31.79 1 4 4 8 6.574E7 6.51 31.79 4 4 448.46 31.79 4 4 151 17.4 5.01 HVO_2130 IclR family transcription regulator 31.62 1 7 7 28 3.116E8 14.63 27.57 6 12 1568.93 31.62 7 16 272 30.1 5.55 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 31.49 1 9 9 46 3.064E9 41.33 31.49 9 22 2575.34 31.49 9 24 435 46.9 4.63 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 38 5.968E9 46.99 31.45 3 18 3371.31 31.45 3 20 124 14.2 5.22 HVO_1488 D-gluconate dehydratase 31.31 1 9 11 74 3.198E9 66.98 31.31 11 36 4491.12 31.31 11 38 412 45.8 4.60 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 31.21 1 11 11 56 1.678E9 50.35 29.51 10 27 3191.69 31.21 11 29 471 51.0 4.48 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 31.10 1 10 10 46 1.046E9 37.15 31.10 10 23 2263.96 29.08 9 23 447 48.5 4.56 HVO_2779 50S ribosomal protein L18e 31.03 1 3 3 7 2.587E7 3.86 31.03 3 3 249.04 31.03 3 4 116 12.7 8.50 HVO_A0266 IclR family transcription regulator 30.98 1 6 6 14 1.363E8 16.45 21.57 4 6 904.82 30.98 6 8 255 27.7 6.05 HVO_0415 repair helicase 30.84 1 15 15 63 1.627E9 47.31 29.38 14 29 3485.80 30.84 14 34 616 69.6 4.70 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 30.84 1 8 8 33 1.353E9 19.97 30.84 8 17 1713.25 30.84 8 16 415 44.4 4.41 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 30.83 1 15 15 79 1.152E9 59.31 27.17 13 37 4600.95 30.83 15 42 600 65.3 4.68 HVO_0874 beta-lactamase domain protein 30.78 1 15 16 81 2.142E9 68.47 28.44 15 40 5334.82 28.28 15 41 640 71.9 5.14 HVO_1187 conserved hypothetical protein 30.77 1 4 4 12 1.073E8 12.13 30.77 4 6 597.52 30.77 4 6 143 16.4 4.86 HVO_2961 dihydrolipoyl dehydrogenase 30.74 1 9 9 31 3.652E8 37.86 25.26 8 15 2107.34 30.74 9 16 475 49.9 4.41 HVO_2040 NAD-dependent epimerase/dehydratase 30.72 1 4 7 44 1.542E9 39.17 24.51 6 21 2735.80 30.72 7 23 306 33.8 4.51 HVO_1657 phosphoribosylamine--glycine ligase 30.61 1 11 11 41 1.581E9 32.30 29.21 10 19 2404.05 30.61 11 22 428 45.5 4.20 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 30.47 1 3 3 16 1.189E8 17.50 30.47 3 8 1072.71 30.47 3 8 128 13.0 4.31 HVO_0388 homolog to ribonuclease R 30.30 1 12 12 42 4.742E8 31.08 30.30 12 21 2278.38 29.16 11 21 439 50.3 4.73 HVO_0358 homoserine dehydrogenase 30.28 1 4 5 14 2.553E8 14.56 28.39 4 7 759.34 22.08 4 7 317 32.4 4.44 HVO_0519 replication protein A 30.23 1 12 12 54 9.331E8 36.84 30.23 12 28 2545.65 25.26 10 26 483 51.0 4.13 HVO_1510 2-isopropylmalate synthase 30.23 1 10 10 41 3.503E9 32.66 30.23 10 21 2226.33 27.50 8 20 440 47.7 4.82 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 30.22 1 12 12 42 7.114E8 37.77 30.22 12 22 2195.71 30.22 12 20 599 65.3 4.51 HVO_2348 GTP cyclohydrolase MptA 30.19 1 6 6 28 9.256E8 17.28 30.19 6 16 1187.55 23.05 5 12 308 33.5 4.68 HVO_1172 NAD-dependent epimerase/dehydratase 30.16 1 7 7 29 2.409E9 24.59 26.67 5 13 1791.35 30.16 7 16 315 34.9 4.34 HVO_0400 conserved hypothetical protein 30.16 1 2 2 3 8.706E7 197.56 30.16 2 3 126 13.9 4.68 HVO_2336 pyridoxal biosynthesis lyase PdxS 30.13 1 6 6 48 9.562E8 41.15 26.49 5 22 3479.30 30.13 6 26 302 32.5 4.81 HVO_A0406 conserved hypothetical protein 30.12 1 1 8 35 8.341E8 27.21 30.12 8 17 2192.02 30.12 8 18 405 44.4 5.30 HVO_2347 conserved hypothetical protein 30.00 1 3 3 10 2.130E8 10.22 30.00 3 5 731.32 30.00 3 5 140 15.5 4.37 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 29.93 1 10 10 27 9.427E8 17.63 24.08 8 12 1457.39 29.93 10 15 461 50.7 4.73 HVO_0041 ornithine carbamoyltransferase 29.77 1 6 6 33 1.016E9 23.90 29.77 6 16 1905.75 29.77 6 17 299 32.7 4.37 HVO_1371 glutamate 5-kinase 29.57 1 6 6 24 1.605E9 16.32 29.57 6 11 1483.86 29.57 6 13 301 32.0 4.25 HVO_1018 RecJ domain protein 29.54 1 15 15 74 1.790E9 62.35 28.28 14 34 4829.54 29.54 15 40 633 69.8 4.58 HVO_2549 30S ribosomal protein S8 29.23 1 4 4 15 8.620E8 5.98 29.23 4 8 580.68 29.23 4 7 130 14.1 4.79 HVO_2425 GNAT family acetyltransferase 29.17 1 6 6 14 1.851E8 7.49 29.17 6 7 538.38 29.17 6 7 216 24.4 4.54 HVO_1778 catalase-peroxidase 29.11 1 14 14 109 4.124E9 104.40 29.11 14 55 6907.75 28.27 13 54 718 80.0 4.31 HVO_1727 TATA-binding transcription initiation factor 29.03 1 5 6 52 2.934E9 43.10 29.03 6 25 3299.69 29.03 6 27 186 19.9 4.36 HVO_2188 phosphoribosylformylglycinamidine synthase 1 29.02 1 5 5 18 9.348E8 15.95 29.02 5 9 853.13 29.02 5 9 224 23.9 4.36 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 28.89 1 5 5 27 4.354E8 30.10 28.89 5 14 1561.23 28.89 5 13 270 29.1 4.35 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 28.53 1 12 12 63 2.717E9 60.42 28.53 12 31 3989.75 28.53 12 32 624 67.6 4.27 HVO_B0018 ParA domain protein 28.22 1 4 4 19 1.203E8 10.04 28.22 4 9 1060.41 28.22 4 10 287 31.7 4.74 HVO_2454 anthranilate synthase component I 27.86 1 11 11 35 1.012E9 28.32 25.76 10 17 1946.59 27.86 11 18 524 55.9 4.56 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 27.81 1 8 8 40 1.407E9 27.15 27.81 8 20 2269.62 27.81 8 20 453 47.5 4.63 HVO_2675 histidinol dehydrogenase 27.80 1 6 6 20 3.945E8 21.07 27.80 6 10 1304.97 27.80 6 10 428 45.4 4.50 HVO_1853 UspA domain protein 27.70 1 3 3 6 8.554E7 0.00 27.70 3 3 121.97 27.70 3 3 148 16.0 4.58 HVO_1087 UspA domain protein 27.66 1 4 4 10 7.877E7 9.31 27.66 4 5 563.16 27.66 4 5 141 15.2 4.98 HVO_0214 L-lactate dehydrogenase 27.50 1 9 9 47 2.727E9 36.89 27.50 9 24 2837.59 20.94 7 23 320 34.5 4.49 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 27.47 1 8 8 33 2.533E8 22.22 27.47 8 17 1730.99 27.47 8 16 364 39.3 4.35 HVO_2239 UspA domain protein 27.46 1 4 4 12 9.664E8 10.58 27.46 4 6 696.60 27.46 4 6 142 15.4 4.16 HVO_0167 adenosylhomocysteinase 27.34 1 9 9 43 1.114E9 32.03 21.50 7 19 2611.39 27.34 9 24 428 46.6 4.39 HVO_0292 replication protein A 27.33 1 7 7 36 6.258E8 24.09 27.33 7 17 2121.53 27.33 7 19 311 34.6 4.31 HVO_0573 endonuclease IV 27.15 1 5 5 25 1.205E9 14.98 27.15 5 12 1344.07 27.15 5 13 291 31.4 4.44 HVO_0549 2-keto-3-deoxygluconate kinase 26.88 1 7 8 38 8.749E8 14.82 23.13 7 19 1860.26 26.88 8 19 320 34.1 4.34 HVO_0350 DNA-directed RNA polymerase subunit A'' 26.73 1 9 9 49 3.157E9 55.70 20.76 8 24 3494.94 26.73 9 25 419 46.1 4.35 HVO_1573 DNA gyrase subunit A 26.68 1 18 18 56 1.278E9 54.68 18.45 14 27 3376.43 25.64 17 29 862 94.8 4.56 HVO_1175 DUF2110 family protein 26.67 1 4 4 22 1.527E9 23.04 26.67 4 11 1691.37 26.67 4 11 225 24.4 4.63 HVO_0349 DNA-directed RNA polymerase subunit A' 26.64 1 22 22 107 1.411E9 80.57 25.10 19 50 6078.74 26.64 22 57 976 108.8 4.81 HVO_A0307 Lrp/AsnC family transcription regulator 26.55 1 4 4 14 1.187E8 8.63 26.55 4 7 722.23 26.55 4 7 177 19.4 4.39 HVO_0867 HD family hydrolase 26.52 1 5 5 12 1.683E8 7.65 26.52 5 6 542.01 26.52 5 6 230 26.2 4.78 HVO_2690 GFO family oxidoreductase 26.50 1 9 9 35 1.403E9 20.87 26.50 9 18 1529.21 26.50 9 17 366 40.0 4.60 HVO_2496 adenylate kinase 26.44 1 5 5 30 3.180E9 29.99 26.44 5 15 1853.00 26.44 5 15 208 23.1 4.25 HVO_0417 metal-dependent carboxypeptidase 26.29 1 10 10 38 7.068E8 40.12 26.29 10 18 2137.23 26.29 10 20 502 57.3 4.42 HVO_0795 transcription initiation factor TFB 26.27 1 5 7 18 2.508E8 14.05 23.58 6 9 989.47 24.48 6 9 335 37.4 5.59 HVO_1989 tRNA (pseudouridine(54)-N(1))-methyltransferase 26.26 1 2 2 6 9.935E7 6.48 26.26 2 3 256.22 26.26 2 3 198 21.9 4.79 HVO_1979 tRNA pseudouridine synthase Pus10 26.23 1 8 8 24 1.099E9 17.44 24.59 7 12 1138.85 20.37 7 12 427 46.9 4.39 HVO_C0069 GFO family oxidoreductase 26.23 1 7 7 22 1.749E8 17.11 26.23 7 12 931.53 20.06 6 10 324 36.0 5.10 HVO_1871 UPF0447 family protein 26.15 1 9 9 35 1.222E9 15.86 22.75 8 16 1722.50 19.76 8 19 501 56.1 4.59 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 12 1.346E8 8.07 26.15 3 6 599.78 26.15 3 6 130 13.4 8.56 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 26.13 1 7 7 16 1.603E8 2.01 21.32 6 8 590.84 22.22 6 8 333 36.7 4.56 HVO_1527 glucose-1-phosphate uridylyltransferase 25.93 1 6 6 33 5.860E8 24.46 25.93 6 17 1929.05 25.93 6 16 243 27.5 4.70 HVO_0467 PhoU/TrkA-C domain protein 25.87 1 9 9 28 2.412E8 19.04 24.13 8 14 1288.61 22.14 8 14 402 43.3 4.49 HVO_1576 NAD-dependent epimerase/dehydratase 25.82 1 4 7 37 8.747E8 32.39 25.82 7 18 2013.61 25.82 7 19 306 33.9 4.51 HVO_1654 cysteine synthase 25.82 1 5 5 17 6.823E8 7.51 25.82 5 8 772.94 25.82 5 9 306 32.3 4.32 HVO_0233 ribose-phosphate pyrophosphokinase 25.80 1 4 4 16 5.739E8 11.75 25.80 4 7 770.41 25.80 4 9 283 29.6 4.40 HVO_0206 alanine--tRNA ligase 25.70 1 19 19 70 5.540E8 39.41 23.75 17 35 3372.62 20.93 16 35 922 102.4 4.54 HVO_1459 ThuA family protein 25.63 1 4 4 26 1.218E9 16.25 25.63 4 13 1405.90 25.63 4 13 238 26.8 4.67 HVO_1412 diphosphomevalonate decarboxylase 25.62 1 8 8 33 1.698E9 16.87 25.62 8 16 1584.94 25.62 8 17 324 35.4 4.78 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 25.58 1 8 8 30 1.420E8 16.73 22.38 7 14 1797.57 25.58 8 16 344 39.1 4.73 HVO_0354 30S ribosomal protein S7 25.49 1 5 5 13 8.993E8 12.29 22.55 4 6 816.36 25.49 5 7 204 22.6 5.14 17318569 keratin 1 [Homo sapiens] 25.16 1 1 17 77 1.728E9 80.80 23.76 16 38 5480.71 25.16 17 39 644 66.0 8.12 >sp|TRYP_PIG| 25.11 1 4 4 113 4.105E10 134.44 25.11 4 57 9051.87 25.11 4 56 231 24.4 7.18 HVO_0787 indole-3-glycerol-phosphate synthase 25.10 1 5 5 12 2.548E8 4.26 25.10 5 6 434.17 25.10 5 6 251 26.7 4.44 HVO_2781 DNA-directed RNA polymerase subunit D 25.10 1 5 5 54 3.077E9 40.72 25.10 5 26 3620.10 25.10 5 28 259 28.1 4.32 HVO_0087 porphobilinogen synthase 25.08 1 7 7 21 3.808E8 10.50 25.08 7 10 930.67 25.08 7 11 327 35.3 4.72 HVO_2436 malic enzyme (NADP) 25.03 1 13 16 66 1.354E9 60.18 25.03 15 32 4220.90 25.03 16 34 751 81.4 4.55 HVO_0034 acyl-CoA thioester hydrolase 25.00 1 4 4 22 2.035E8 18.38 25.00 3 11 1149.70 25.00 4 11 164 18.3 4.65 HVO_0401 UspA domain protein 25.00 1 3 3 18 1.006E9 22.78 25.00 3 9 1361.18 25.00 3 9 152 16.4 4.79 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 24.93 1 8 8 65 3.976E9 68.75 24.93 8 31 4050.15 24.93 8 34 357 40.3 4.40 HVO_1575 arginase 24.75 1 3 3 16 4.523E8 2.58 24.75 3 8 461.45 24.75 3 8 299 31.0 4.58 HVO_1690 DHH family phosphoesterase 24.74 1 7 7 32 3.140E8 39.26 24.74 7 16 2248.25 24.74 7 16 485 52.1 4.48 HVO_B0115 fumarylacetoacetase family protein 24.73 1 4 4 15 5.406E8 9.40 24.73 4 7 794.25 24.73 4 8 283 30.3 4.21 HVO_1571 DNA topoisomerase VI subunit B 24.69 1 13 13 60 6.690E8 54.58 22.31 12 29 3524.93 24.69 13 31 798 87.4 4.73 HVO_B0061 precorrin-2 C20-methyltransferase 24.68 1 4 4 11 1.434E8 8.31 14.47 3 5 592.91 24.68 4 6 235 25.3 4.63 HVO_A0331 D-galactonate dehydratase 24.48 1 5 6 13 1.115E8 4.39 20.83 5 6 618.77 24.48 6 7 384 42.8 4.83 HVO_1866 uridylate kinase 24.47 1 4 4 18 7.758E8 12.45 24.47 4 9 952.68 24.47 4 9 237 24.6 4.42 HVO_A0432 conserved hypothetical protein 24.44 1 0 7 29 5.266E8 27.21 24.44 7 14 2018.27 24.44 7 15 405 44.5 5.24 HVO_1076 sugar nucleotidyltransferase 24.22 1 6 6 26 1.018E9 13.70 24.22 6 14 1361.31 22.36 5 12 322 35.8 4.20 HVO_1593 PAC2 family protein 24.19 1 3 3 12 4.446E8 4.31 24.19 3 6 418.08 24.19 3 6 248 26.6 4.46 HVO_0911 GTP-binding protein Drg 24.12 1 8 8 16 7.901E7 7.01 24.12 8 9 463.06 19.24 7 7 369 40.5 4.81 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 23.76 1 0 16 73 1.728E9 78.84 22.36 15 36 5261.26 23.76 16 37 644 66.0 8.12 HVO_2417 conserved hypothetical protein 23.59 1 3 3 12 5.472E8 13.22 23.59 3 5 774.29 23.59 3 7 195 21.6 3.65 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 23.56 1 6 6 22 2.479E8 17.71 23.56 6 11 972.92 23.56 6 11 365 39.0 4.61 HVO_1823 UspA domain protein 23.53 1 3 3 9 2.724E8 7.99 14.38 2 4 480.35 23.53 3 5 153 16.4 4.60 HVO_1025 acetyl-CoA C-acyltransferase 23.50 1 6 6 24 6.374E8 27.48 23.50 6 12 1535.09 23.50 6 12 383 40.7 4.56 HVO_2912 ThiJ/PfpI domain protein 23.38 1 2 2 10 9.699E7 2.06 23.38 2 5 305.40 23.38 2 5 201 20.9 4.36 HVO_0699 translation initiation factor aIF-2 alpha subunit 23.31 1 6 6 31 6.267E8 25.85 23.31 6 16 1666.42 23.31 6 15 266 29.5 4.46 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 23.24 1 8 8 45 3.037E9 35.30 23.24 8 23 2713.18 23.24 8 22 370 41.9 4.48 HVO_1496 phosphotransferase system component I 23.19 1 10 10 40 6.316E8 26.84 23.19 10 20 2142.80 23.19 10 20 565 60.3 4.21 HVO_1572 DNA gyrase subunit B 23.16 1 12 12 42 4.962E8 23.67 21.60 11 20 1947.66 23.16 12 22 639 71.2 4.83 HVO_0829 peptidase S9 family protein 23.03 1 8 8 31 4.269E8 23.71 20.07 7 15 1745.34 19.08 7 16 608 67.4 4.54 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 22.95 1 6 6 22 4.124E8 17.36 22.95 6 11 1093.40 22.95 6 11 427 45.4 4.56 HVO_0243 threonine aldolase 22.87 1 5 5 16 1.863E8 15.38 19.35 4 7 1112.52 22.87 5 9 341 35.6 4.55 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 22.87 1 9 9 32 6.032E8 19.36 20.48 8 16 1659.28 22.87 9 16 586 63.4 4.70 HVO_2435 peptidase M24 family protein 22.83 1 5 5 20 3.578E8 13.76 22.83 5 10 999.94 22.83 5 10 368 40.0 4.53 HVO_B0371 aldehyde dehydrogenase 22.78 1 6 6 18 1.583E8 20.75 19.96 5 9 905.15 22.78 6 9 496 52.5 4.39 HVO_0484 50S ribosomal protein L10e 22.73 1 3 3 8 1.314E8 8.69 22.73 3 4 489.05 22.73 3 4 176 19.8 8.72 HVO_1020 HEAT-PBS family protein 22.67 1 7 7 38 4.070E8 34.19 22.67 7 17 2377.03 22.67 7 21 419 45.5 3.95 HVO_2643 NADPH:quinone reductase 22.54 1 4 4 23 4.987E8 25.48 22.54 4 11 1556.58 22.54 4 12 346 37.2 4.55 HVO_A0485 aminotransferase class V 22.51 1 5 5 14 2.502E8 4.67 22.51 5 7 461.32 22.51 5 7 351 37.3 4.26 HVO_1550 acyl-CoA thioester hydrolase 22.50 1 3 3 10 1.118E8 5.66 22.50 3 5 448.74 22.50 3 5 160 17.6 4.55 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 22.43 1 8 8 27 9.591E8 12.99 16.73 7 13 1149.99 22.43 8 14 526 57.2 4.31 HVO_2373 30S ribosomal protein S8e 22.40 1 3 3 8 1.016E8 7.58 22.40 3 4 332.40 22.40 3 4 125 13.6 10.48 HVO_1649 methionine adenosyltransferase 22.39 1 6 6 24 8.183E8 13.63 17.16 5 12 1209.04 22.39 6 12 402 43.5 4.45 HVO_1048 phosphoribosylformylglycinamidine synthase 2 22.36 1 10 10 67 8.788E8 79.14 19.66 8 32 4776.55 22.36 10 35 702 72.9 4.18 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 22.31 1 6 6 15 4.366E8 4.64 14.44 4 5 683.42 22.31 6 10 381 40.5 4.51 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 22.28 1 4 4 13 3.524E8 5.13 22.28 4 6 528.24 15.38 3 7 377 39.2 4.18 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 22.22 1 4 4 15 4.484E8 19.07 22.22 4 8 1071.23 19.14 3 7 324 33.6 3.99 HVO_1880 conserved hypothetical protein 22.22 1 4 4 12 8.714E7 6.58 14.67 3 6 638.88 22.22 4 6 225 23.8 4.59 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 22.22 1 5 5 24 1.394E9 25.65 17.86 4 11 1883.14 22.22 5 13 252 26.0 4.39 HVO_0876 methylglyoxal synthase 22.05 1 2 2 4 1.202E8 1.65 22.05 2 2 99.74 22.05 2 2 127 13.9 4.48 HVO_1508 acetolactate synthase large subunit 21.98 1 8 8 47 1.582E9 65.17 21.98 8 24 3762.07 20.61 7 23 587 62.3 4.36 HVO_1847 oligoendopeptidase PepF 21.87 1 10 10 34 4.226E8 28.69 21.87 10 17 1756.16 21.87 10 17 599 68.5 4.41 HVO_2793 conserved hypothetical protein 21.83 1 3 3 3 1.176E8 4.14 21.83 3 3 252 27.1 4.46 HVO_1623 conserved hypothetical protein 21.81 1 5 5 26 3.993E8 19.81 21.81 5 14 1244.71 21.81 5 12 298 32.8 4.56 HVO_1896 30S ribosomal protein S24e 21.78 1 2 2 4 1.305E7 4.41 21.78 2 2 270.22 21.78 2 2 101 11.6 4.68 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 21.72 1 3 4 12 3.653E8 16.24 21.72 4 6 850.72 21.72 4 6 267 29.1 4.63 HVO_2948 phenylalanine--tRNA ligase alpha subunit 21.64 1 6 6 34 7.891E8 27.42 21.64 6 17 1593.91 21.64 6 17 499 55.1 4.41 HVO_1038 uracil-DNA glycosylase superfamily protein 21.63 1 2 2 2 1.114E8 90.53 21.63 2 2 208 22.7 4.61 HVO_1073 ThiJ/PfpI family protein 21.43 1 4 4 20 2.609E8 17.16 21.43 4 10 1026.34 21.43 4 10 224 23.9 4.12 HVO_0429 archaemetzincin 21.39 1 2 2 7 8.956E7 6.77 21.39 2 4 265.64 21.39 2 3 173 19.3 6.54 HVO_1804 nicotinate phosphoribosyltransferase 21.39 1 7 7 22 2.986E8 12.21 18.30 6 9 1093.80 21.39 7 13 388 41.1 4.60 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 21.38 1 12 12 72 1.427E9 44.37 18.51 10 34 4413.87 21.38 12 38 697 74.5 4.13 HVO_2547 50S ribosomal protein L32e 21.28 1 4 4 18 3.100E8 23.89 21.28 4 9 1489.09 21.28 4 9 235 25.8 4.75 HVO_2156 UspA domain protein 21.26 1 5 5 21 8.226E8 12.46 21.26 5 11 1264.15 21.26 5 10 301 31.6 4.69 HVO_0937 FMN-binding domain protein 21.23 1 2 2 6 4.564E7 4.59 21.23 2 3 251.12 21.23 2 3 146 16.2 4.36 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 21.19 1 8 8 38 4.508E8 25.65 21.19 8 19 1734.08 21.19 8 19 623 62.1 5.30 HVO_1957 proteasome-activating nucleotidase 21.12 1 5 6 17 1.851E8 15.48 21.12 6 8 1034.56 21.12 6 9 412 45.6 4.48 HVO_1932 2-D-hydroxyacid dehydrogenase 21.10 1 6 6 21 2.980E8 15.70 21.10 6 11 718.17 17.53 5 10 308 33.0 4.60 HVO_2481 HD family hydrolase 21.03 1 4 4 10 1.181E8 5.47 21.03 4 6 289.89 16.92 3 4 390 42.7 6.14 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 20.99 1 5 5 24 7.411E8 21.87 20.99 5 12 1474.34 20.99 5 12 362 39.6 4.82 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 20.93 1 6 6 27 1.842E8 26.19 20.93 6 13 1198.68 20.93 6 14 430 45.1 4.50 HVO_1079 sulfate adenylyltransferase small subunit 20.92 1 5 5 13 2.429E8 6.80 13.54 4 6 503.28 20.92 5 7 325 37.5 4.18 HVO_2960 dihydrolipoamide S-acyltransferase 20.92 1 8 8 33 2.184E8 32.39 20.92 8 18 1856.02 19.39 7 15 521 54.9 4.40 HVO_2536 CHP00300 family protein 20.91 1 4 4 8 3.694E8 2.45 14.18 3 4 261.57 13.46 3 4 416 44.8 4.51 HVO_2717 alanine--tRNA ligase 20.85 1 7 7 20 1.740E8 14.80 17.84 6 10 1282.40 20.85 7 10 398 41.6 4.39 HVO_1295 histidinol-phosphate aminotransferase 20.78 1 5 5 16 2.702E8 16.33 20.78 5 9 719.44 20.78 5 7 361 39.4 4.51 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 10 1.523E7 10.57 20.71 2 5 677.10 20.71 2 5 140 16.0 5.57 HVO_1338 replication protein A 20.61 1 7 7 31 7.230E8 18.13 20.61 7 16 1466.55 20.61 7 15 427 46.0 4.36 HVO_2947 phenylalanine--tRNA ligase beta subunit 20.53 1 9 9 37 1.101E9 20.10 18.42 7 17 2313.92 20.53 9 20 570 63.3 4.46 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 20.47 1 3 3 13 4.088E8 5.04 20.47 3 8 301.55 20.47 3 5 386 42.1 4.49 HVO_1578 probable NADH dehydrogenase 20.40 1 4 4 15 4.637E8 20.43 13.85 3 7 741.21 20.40 4 8 397 42.8 4.40 HVO_1698 CBS/parB domain protein 20.38 1 3 4 16 9.582E8 4.20 20.38 4 8 488.30 20.38 4 8 265 29.4 4.92 HVO_2013 "FtsZ family protein, type III" 20.30 1 3 4 15 1.698E8 21.54 20.30 4 8 1477.16 20.30 4 7 394 41.5 4.61 HVO_2205 arNOG06768 family NADH-binding domain protein 20.27 1 4 4 12 2.693E7 9.76 20.27 4 6 600.86 20.27 4 6 301 32.0 5.00 40354192 keratin 10 [Homo sapiens] 20.21 1 0 12 35 2.663E8 28.32 16.95 11 18 1826.39 18.66 10 17 584 58.8 5.16 HVO_B0382 TATA-binding transcription initiation factor 20.21 1 3 3 8 1.058E8 6.60 20.21 3 4 333.47 20.21 3 4 188 20.1 4.12 HVO_2168 AAA-type ATPase (MoxR subfamily) 20.06 1 5 5 16 2.372E8 5.05 20.06 5 8 636.43 14.89 4 8 329 35.9 4.54 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 20.06 1 5 5 17 3.746E8 4.63 20.06 5 8 597.23 20.06 5 9 339 38.1 4.50 HVO_2380 AAA-type ATPase (CDC48 subfamily) 19.92 1 11 11 27 2.452E8 13.04 16.15 9 12 1127.16 19.92 11 15 743 81.9 4.82 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 19.90 1 0 12 35 2.663E8 28.32 16.69 11 18 1826.39 18.38 10 17 593 59.5 5.21 HVO_2951 tryptophan--tRNA ligase 19.85 1 6 6 14 2.076E8 3.76 12.10 4 6 419.97 19.85 6 8 529 59.1 4.53 HVO_0812 phosphoenolpyruvate synthase 19.84 1 10 10 25 2.490E8 14.10 19.84 10 15 1010.51 11.04 7 10 761 83.1 4.63 HVO_2614 uridine phosphorylase 19.83 1 4 4 27 1.586E9 23.84 17.77 3 12 1570.94 19.83 4 15 242 25.8 4.30 HVO_1503 3-isopropylmalate dehydratase small subunit 19.80 1 3 3 12 6.653E8 8.07 10.89 2 5 719.07 19.80 3 7 202 22.0 4.15 HVO_2712 3'-5' RNA ligase 19.75 1 6 6 18 1.461E8 13.87 19.75 6 9 779.51 19.75 6 9 486 53.4 4.92 HVO_2580 L-aspartate oxidase 19.74 1 7 7 27 1.132E8 21.52 18.62 6 14 1322.25 19.74 7 13 537 55.8 4.63 HVO_1867 lysine--tRNA ligase 19.64 1 8 8 17 5.106E8 8.83 18.02 7 8 697.26 19.64 8 9 555 62.1 4.46 HVO_0601 homoserine dehydrogenase 19.62 1 4 5 28 7.796E8 33.51 17.72 4 14 2020.81 19.62 5 14 316 32.2 4.25 HVO_2707 GFO family oxidoreductase 19.62 1 6 6 18 4.678E8 8.16 19.62 6 9 789.37 19.62 6 9 372 41.0 4.55 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 19.57 1 2 2 13 4.352E8 5.17 19.57 2 7 407.24 19.57 2 6 184 20.0 4.75 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 19.37 1 3 3 10 7.772E7 9.71 19.37 3 5 655.66 19.37 3 5 253 26.0 4.60 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 44 3.231E9 36.32 19.31 5 21 2893.77 19.31 5 23 378 39.7 4.67 HVO_0017 conserved hypothetical protein 19.27 1 3 3 14 4.988E8 10.34 19.27 3 7 812.60 19.27 3 7 192 21.9 4.50 HVO_1164 HD family hydrolase 19.26 1 4 4 20 4.628E8 12.22 19.26 4 9 986.19 19.26 4 11 270 29.8 4.87 HVO_1478 transcription initiation factor TFB 19.24 1 3 6 27 7.279E8 27.44 16.72 5 13 1878.18 19.24 6 14 317 35.7 5.47 HVO_1783 conserved hypothetical protein 19.20 1 3 3 8 5.310E7 4.66 14.73 2 3 417.06 19.20 3 5 224 24.1 5.90 HVO_0894 acyl-CoA synthetase 19.18 1 5 9 29 2.604E8 14.76 19.18 9 14 1000.62 19.18 9 15 662 74.3 4.48 HVO_0357 ACT domain protein 19.05 1 3 3 13 2.398E8 9.83 19.05 3 7 423.18 19.05 3 6 189 20.2 4.59 HVO_1289 OsmC domain protein 18.94 1 2 2 102 2.718E9 137.16 18.94 2 53 8904.60 18.94 2 49 132 14.2 3.85 HVO_A0458 ParA domain protein 18.90 1 3 3 8 2.833E8 2.02 18.90 3 4 330.69 18.90 3 4 291 32.2 4.79 HVO_0697 PAC2 family protein 18.82 1 2 2 19 8.561E8 22.34 18.82 2 9 1500.10 18.82 2 10 255 27.4 4.08 HVO_1567 conserved hypothetical protein 18.72 1 3 3 8 2.645E8 3.58 18.72 3 4 398.50 18.72 3 4 235 25.7 4.36 HVO_1287 PfpI family protease 18.69 1 2 2 8 1.451E8 5.66 18.69 2 4 239.36 18.69 2 4 198 21.5 4.53 HVO_2879 ornithine cyclodeaminase 18.67 1 4 4 11 4.942E8 8.00 11.14 3 5 526.40 18.67 4 6 332 34.6 4.45 7428712 "keratin 1, type II, cytoskeletal - human" 18.66 1 0 13 56 1.170E9 63.67 17.26 12 27 3958.28 18.66 13 29 643 65.5 6.35 HVO_1660 DisA-N domain protein 18.59 1 4 4 13 6.565E8 11.69 18.59 4 6 613.85 18.59 4 7 269 28.9 4.73 HVO_1570 DNA topoisomerase VI subunit A 18.58 1 6 6 15 3.211E8 9.53 15.85 5 7 868.66 18.58 6 8 366 41.8 4.63 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 18.58 1 15 15 59 4.639E8 67.51 15.43 12 27 5066.40 16.64 14 32 1082 117.2 4.32 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 18.42 1 4 4 16 1.659E8 13.32 18.42 4 8 1001.11 18.42 4 8 266 29.7 4.32 HVO_0868 NAD-dependent epimerase/dehydratase 18.24 1 5 5 12 1.066E8 3.81 18.24 5 7 379.94 16.41 4 5 329 36.1 4.55 HVO_0056 conserved hypothetical protein 18.23 1 2 2 4 1.192E8 0.00 18.23 2 2 74.63 18.23 2 2 192 20.9 4.16 HVO_1453 glutamate dehydrogenase (NADP) 18.23 1 6 6 18 3.597E8 12.87 18.23 6 10 797.13 16.31 5 8 417 45.7 4.49 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 18.21 1 7 7 28 5.744E8 22.01 18.21 7 14 1242.80 18.21 7 14 615 67.6 4.88 HVO_1235 creatininase 18.18 1 3 3 11 6.648E7 1.66 18.18 3 4 419.55 18.18 3 7 264 29.2 4.84 HVO_2883 conserved hypothetical protein 18.09 1 9 9 20 2.012E8 10.56 16.10 8 10 700.83 16.95 8 10 702 78.9 4.48 HVO_0054 glycine--tRNA ligase 18.01 1 7 7 35 3.089E9 26.63 15.66 6 16 2197.69 18.01 7 19 594 64.9 4.21 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 17.87 1 6 6 34 1.260E9 38.96 17.87 6 17 2159.26 17.87 6 17 347 36.8 4.93 HVO_2333 conserved hypothetical protein 17.86 1 6 6 11 1.875E8 7.86 14.61 5 6 451.49 12.99 4 5 308 34.9 4.54 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 17.84 1 3 3 10 6.563E8 4.20 17.84 3 5 474.76 17.84 3 5 269 28.3 4.49 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 17.74 1 4 4 12 2.334E8 5.71 17.74 4 6 485.03 17.74 4 6 265 28.7 4.87 HVO_1327 AAA-type ATPase (CDC48 subfamily) 17.66 1 6 7 19 2.854E8 10.54 15.63 6 9 708.98 17.66 7 10 736 78.1 4.88 HVO_0452 leucine--tRNA ligase 17.64 1 12 12 31 4.393E8 20.29 15.14 9 14 1555.78 17.64 12 17 958 109.5 4.37 HVO_0661 dCTP deaminase (dUMP-forming) 17.44 1 2 2 8 2.177E8 1.89 17.44 2 4 276.69 17.44 2 4 195 21.2 4.59 HVO_1291 fumarylacetoacetase family protein 17.28 1 2 2 8 1.298E9 8.64 17.28 2 4 466.31 17.28 2 4 243 26.3 4.55 HVO_2906 tRNA (cytidine/uridine-2'-O-)-methyltransferase 17.09 1 2 2 2 3.155E7 0.00 17.09 2 2 275 30.6 4.58 HVO_2708 YfiH family protein 17.08 1 4 4 15 6.698E8 16.26 17.08 4 8 834.29 12.73 3 7 322 35.4 4.35 HVO_2008 archaeosine synthase 16.92 1 8 8 24 9.332E8 5.59 15.21 7 11 902.84 16.92 8 13 585 64.9 4.81 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 16.89 1 6 6 19 1.077E9 10.58 15.01 5 9 948.57 14.48 5 10 373 40.2 4.44 HVO_0997 peptidase M24 family protein 16.85 1 3 3 12 6.419E7 6.83 16.85 3 6 584.10 16.85 3 6 368 39.9 4.49 HVO_1531 UDP-glucose 6-dehydrogenase 16.74 1 5 5 19 3.165E8 10.83 16.74 5 9 699.21 16.74 5 10 430 45.9 4.50 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 16.60 1 3 3 8 1.061E8 6.81 16.60 3 5 334.37 10.94 2 3 265 29.3 4.92 HVO_0042 acetylornithine deacetylase 16.54 1 3 3 9 1.504E9 6.20 16.54 3 5 497.57 7.87 2 4 381 41.0 4.34 HVO_2923 proteasome alpha subunit 16.47 1 3 4 18 7.627E8 10.46 16.47 4 9 817.57 16.47 4 9 249 26.7 4.39 HVO_0321 peptide chain release factor aRF-1 16.43 1 5 5 11 3.315E8 8.64 16.43 5 6 525.03 11.11 4 5 414 46.6 4.83 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 16.40 1 3 3 8 1.665E8 4.27 9.52 2 3 379.82 16.40 3 5 189 21.7 4.46 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 16.39 1 3 3 8 1.382E8 4.65 16.39 3 5 156.52 16.39 3 3 305 32.7 4.56 HVO_1500 1-phosphofructokinase 16.39 1 3 3 8 2.486E8 1.69 16.39 3 5 173.54 12.13 2 3 305 32.0 4.51 HVO_2072 S-layer glycoprotein 16.32 1 6 6 80 2.276E9 50.08 12.82 5 44 2212.14 16.32 6 36 827 85.1 3.65 HVO_2068 "FtsZ family protein, type III" 16.22 1 4 5 14 2.415E8 14.15 16.22 5 7 1061.00 16.22 5 7 370 38.7 4.49 HVO_2688 TrmB family transcription regulator 16.15 1 5 5 25 1.034E9 24.76 16.15 5 12 1688.75 16.15 5 13 353 39.3 4.58 HVO_1134 conserved hypothetical protein 16.12 1 7 7 22 2.991E8 22.45 16.12 7 11 1296.56 16.12 7 11 757 80.6 4.35 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 16.11 1 4 4 25 6.823E8 13.55 13.06 3 12 1387.72 16.11 4 13 360 38.5 4.45 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 16.02 1 3 3 20 1.523E8 13.55 16.02 3 9 1160.60 16.02 3 11 231 25.0 4.25 HVO_2721 amidophosphoribosyltransferase 16.02 1 5 5 21 1.518E9 19.28 16.02 5 11 1017.14 11.36 4 10 493 53.4 4.78 HVO_1824 conserved hypothetical protein 15.62 1 6 6 20 4.960E8 21.25 15.62 6 10 1659.77 15.62 6 10 429 47.4 4.20 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 15.61 1 2 2 4 1.956E7 1.69 15.61 2 2 134.99 15.61 2 2 237 26.2 4.70 HVO_0044 acetylglutamate kinase 15.60 1 4 4 17 6.355E8 17.38 13.15 3 8 1219.62 15.60 4 9 327 33.2 4.49 HVO_2784 30S ribosomal protein S13 15.57 1 3 3 5 5.691E8 0.00 15.57 3 3 149.28 11.98 2 2 167 18.9 5.17 HVO_2060 NUDIX family hydrolase 15.38 1 2 2 4 3.357E8 0.00 15.38 2 2 147.61 15.38 2 2 156 17.7 4.41 HVO_1967 glucose-6-phosphate isomerase 15.35 1 4 4 14 4.525E8 5.39 15.35 4 7 580.09 10.93 3 7 430 45.6 4.40 HVO_0195 ribose-5-phosphate isomerase 15.22 1 3 3 8 4.872E8 3.71 15.22 3 4 324.67 15.22 3 4 230 23.2 4.54 HVO_A0087 fumarylacetoacetase family protein 15.22 1 3 3 15 8.829E8 20.05 15.22 3 8 864.65 15.22 3 7 289 32.0 4.21 HVO_2777 30S ribosomal protein S9 15.15 1 2 2 8 1.401E8 1.81 15.15 2 4 348.51 15.15 2 4 132 14.7 9.74 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 15.13 1 6 6 19 2.511E8 18.09 13.24 5 9 1120.80 15.13 6 10 423 43.9 4.31 HVO_0122 phosphoglycerate dehydrogenase 15.12 1 3 3 7 2.506E7 6.12 8.02 2 3 319.64 15.12 3 4 324 35.3 5.35 HVO_A0133 conserved hypothetical protein 15.07 1 3 3 8 2.005E8 6.62 15.07 3 4 390.15 15.07 3 4 292 30.8 5.17 HVO_2350 YyaL family protein 14.86 1 4 4 11 1.592E8 3.80 12.14 3 5 605.47 14.86 4 6 552 58.8 4.59 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 14.85 1 4 4 28 4.693E8 8.34 14.85 4 14 1169.23 14.85 4 14 357 39.8 4.41 HVO_2564 50S ribosomal protein L3 14.79 1 4 4 10 6.469E7 6.50 14.79 4 5 317.49 14.79 4 5 338 37.2 6.68 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 14.77 1 3 3 15 3.872E8 3.69 14.77 3 7 464.20 14.77 3 8 237 25.4 4.46 HVO_1174 transcription initiation factor TFE 14.77 1 3 3 8 1.137E8 4.24 7.39 2 3 488.72 14.77 3 5 176 20.6 4.23 HVO_2313 siroheme decarboxylase AhbB 14.73 1 2 2 8 5.866E8 8.71 14.73 2 4 589.25 14.73 2 4 353 39.6 4.64 HVO_1491 HAD superfamily hydrolase 14.71 1 5 5 17 1.212E8 9.96 14.71 5 9 930.85 14.71 5 8 408 44.4 4.60 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 14.64 1 15 15 43 4.459E8 15.24 13.24 13 21 1653.45 13.47 14 22 1284 141.2 4.35 HVO_2945 valine--tRNA ligase 14.60 1 10 10 42 5.997E8 32.95 12.30 8 19 2892.76 14.60 10 23 870 98.9 4.36 HVO_1553 hydroxypyruvate reductase 14.48 1 4 4 8 6.846E7 4.06 10.41 3 3 337.68 14.48 4 5 442 45.2 4.50 HVO_B0059 cobalt-precorrin 5A hydrolase 14.42 1 4 4 12 2.299E8 14.98 14.42 4 6 754.39 14.42 4 6 326 34.5 4.51 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 14.33 1 4 4 16 2.732E8 17.27 14.33 4 8 887.45 14.33 4 8 349 37.0 4.70 HVO_2662 homolog to lactoylglutathione lyase 14.29 1 4 4 11 1.062E9 8.54 11.25 3 5 455.18 14.29 4 6 329 36.5 4.48 HVO_1348 probable YjeF family carbohydrate kinase 14.23 1 4 4 9 1.409E8 4.29 11.51 3 4 260.55 14.23 4 5 478 48.8 4.45 HVO_2761 mevalonate kinase 14.17 1 3 3 8 8.649E7 3.89 14.17 3 4 390.29 14.17 3 4 367 38.2 4.31 HVO_A0545 TetR family transcription regulator 14.07 1 2 2 4 3.852E7 1.79 14.07 2 2 134.84 14.07 2 2 199 23.0 4.78 HVO_2600 methionyl aminopeptidase 13.85 1 4 4 12 2.991E8 7.02 9.80 3 4 611.45 13.85 4 8 296 32.3 4.41 HVO_0234 conserved hypothetical protein 13.82 1 2 2 4 3.180E7 2.05 13.82 2 2 158.40 13.82 2 2 275 28.1 4.48 HVO_0572 lipoate-protein ligase 13.82 1 2 2 4 4.868E7 3.32 13.82 2 2 164.02 13.82 2 2 275 30.5 4.84 HVO_0970 ribulose-bisphosphate carboxylase large subunit 13.77 1 6 6 19 2.298E8 9.79 13.77 6 10 925.27 12.08 5 9 414 43.9 4.59 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 13 6.517E8 4.81 13.66 2 6 687.53 13.66 2 7 183 20.0 4.21 HVO_2421 probable DNA-binding protein 13.62 1 3 3 7 7.184E7 3.84 13.62 3 3 378.61 13.62 3 4 235 25.8 4.89 HVO_0853 DNA double-strand break repair protein Mre11 13.61 1 4 4 14 1.839E8 18.55 13.61 4 7 754.57 13.61 4 7 441 48.1 4.39 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 13.53 1 5 5 13 1.895E8 6.34 13.53 5 6 457.93 13.53 5 7 584 63.3 4.79 HVO_1816 dihydroorotase 13.52 1 5 5 20 1.772E8 6.44 11.66 4 9 769.55 13.52 5 11 429 45.4 4.40 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 13.35 1 5 5 13 7.185E7 6.35 13.35 5 7 501.32 13.35 5 6 442 46.9 4.58 HVO_2256 DUF262 family protein 13.20 1 6 6 24 3.635E8 21.07 13.20 6 12 1693.46 13.20 6 12 462 54.9 4.89 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 13.00 1 3 3 16 2.706E8 13.68 13.00 3 7 958.80 13.00 3 9 277 30.6 4.30 HVO_0466 citrate (si)-synthase 12.93 1 4 4 30 1.531E9 22.18 12.93 4 14 1692.72 12.93 4 16 379 41.8 4.55 HVO_B0200 malate synthase 12.84 1 3 3 6 7.083E8 4.26 12.84 3 3 306.96 12.84 3 3 436 48.3 4.30 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 12.73 1 2 3 8 1.618E8 7.92 12.73 3 4 356.32 12.73 3 4 267 28.8 4.55 HVO_1878 NAD synthase 12.68 1 3 3 8 3.155E8 4.49 12.68 3 4 310.22 12.68 3 4 276 29.6 4.37 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 12.67 1 3 3 21 1.042E9 19.24 12.67 3 11 1464.95 12.67 3 10 363 39.7 4.25 HVO_2639 DUF1611 family protein 12.61 1 4 4 15 4.582E7 14.09 12.61 4 7 822.73 12.61 4 8 341 36.3 4.44 HVO_A0547 DUF1028 family protein 12.61 1 3 3 8 2.746E7 8.10 12.61 3 4 493.40 12.61 3 4 333 35.2 4.16 HVO_0818 threonine synthase 12.60 1 4 4 20 4.172E8 12.58 12.60 4 10 1077.55 12.60 4 10 389 40.8 4.31 HVO_2965 phosphoserine phosphatase 12.56 1 2 2 4 4.642E7 2.12 12.56 2 2 119.68 12.56 2 2 215 23.2 4.51 HVO_2763 homolog to ribonuclease Z 12.50 1 3 3 6 1.323E8 1.79 12.50 3 3 188.88 12.50 3 3 248 26.6 4.53 HVO_A0486 hydrogenase expression/formation protein 12.50 1 2 2 9 1.041E8 4.62 12.50 2 5 313.89 12.50 2 4 336 33.8 4.06 HVO_1594 tRNA/rRNA cytosine-C5-methylase 12.46 1 3 3 9 1.139E8 4.08 7.67 2 4 367.29 12.46 3 5 313 34.6 4.69 HVO_1372 pyrroline-5-carboxylate reductase 12.45 1 3 3 9 4.951E8 8.45 12.45 3 4 771.52 12.45 3 5 257 26.8 4.01 HVO_0733 transcription initiation factor TFB 12.27 1 1 4 15 7.279E8 8.84 9.82 3 7 1006.80 12.27 4 8 326 37.2 6.00 HVO_1547 isoleucine--tRNA ligase 12.27 1 8 8 37 7.032E8 42.55 11.03 7 18 2486.12 12.27 8 19 1043 117.9 4.30 HVO_0197 PurE family protein 12.25 1 3 3 6 5.608E7 2.00 8.70 2 2 225.47 12.25 3 4 253 25.5 4.42 HVO_1337 rpa-associated protein 12.20 1 6 6 21 8.770E8 19.26 12.20 6 10 1168.15 12.20 6 11 623 64.8 3.68 HVO_1879 enoyl-CoA hydratase 12.12 1 3 3 6 1.486E7 3.69 12.12 3 3 244.74 12.12 3 3 231 24.3 5.21 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 12.01 1 3 3 12 1.301E8 8.45 12.01 3 6 569.50 12.01 3 6 383 42.0 4.49 HVO_2229 flavin-containing amine-oxidoreductase 11.92 1 3 3 8 8.453E7 2.03 9.01 2 4 207.88 11.92 3 4 344 37.9 4.92 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 11.85 1 3 3 8 9.849E7 8.63 11.85 3 4 526.53 11.85 3 4 329 36.3 4.49 HVO_2412 Lrp/AsnC family transcription regulator 11.80 1 2 2 6 6.932E7 0.00 11.80 2 3 186.84 11.80 2 3 161 17.7 4.55 HVO_2610 deoxyribose-phosphate aldolase 11.79 1 2 2 2 1.850E8 2.39 11.79 2 2 212 21.9 4.23 HVO_0406 RNA-binding protein AU-1 11.75 1 4 4 8 1.276E8 2.75 11.75 4 4 377.77 11.75 4 4 468 49.9 4.53 HVO_0228 ParA domain protein 11.74 1 2 2 3 3.225E8 242.55 11.74 2 3 247 24.6 4.16 HVO_0158 TATA-binding transcription initiation factor 11.64 1 1 2 8 8.913E8 8.94 11.64 2 4 492.14 11.64 2 4 189 20.3 4.22 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 11.64 1 4 4 15 1.293E8 8.80 11.64 4 7 803.01 11.64 4 8 378 39.8 4.45 HVO_B0287 TRAM domain protein 11.63 1 2 2 2 5.236E7 139.44 11.63 2 2 172 18.0 4.31 HVO_0979 NADH dehydrogenase-like complex subunit B 11.59 1 3 3 10 2.340E8 9.28 11.59 3 5 528.52 11.59 3 5 233 26.1 5.01 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 11.43 1 2 2 4 1.147E8 4.69 11.43 2 2 266.94 11.43 2 2 280 30.0 4.92 HVO_A0268 class II aldolase (homolog to L-fuculose-phosphate aldolase) 11.43 1 2 2 4 3.812E7 5.33 11.43 2 2 236.32 11.43 2 2 446 47.9 4.39 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 11.42 1 3 3 10 2.167E8 7.18 11.42 3 5 343.57 11.42 3 5 464 53.1 4.54 HVO_0120 signal recognition particle receptor FtsY 11.40 1 2 2 4 0.000E0 2.65 11.40 2 2 269.97 11.40 2 2 456 48.2 4.17 HVO_0123 signal recognition particle 54K protein 11.40 1 5 5 12 4.002E8 6.05 9.25 4 5 738.21 11.40 5 7 465 50.9 4.50 HVO_1344 SBDS family protein 11.34 1 2 2 7 5.821E7 6.23 11.34 2 3 342.57 11.34 2 4 238 26.5 4.51 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 11.31 1 3 3 6 1.516E8 0.00 7.95 2 2 215.51 11.31 3 4 327 36.0 4.73 HVO_2759 peptidase M42 family protein 11.30 1 3 3 16 3.679E8 16.23 11.30 3 8 971.02 11.30 3 8 354 37.0 4.40 HVO_1129 conserved hypothetical protein 11.28 1 2 3 11 8.938E8 12.65 10.00 2 5 566.60 11.28 3 6 390 43.0 4.44 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 11.15 1 2 2 6 2.409E7 2.18 11.15 2 3 269.14 11.15 2 3 305 34.1 4.91 HVO_2918 thymidylate synthase 11.14 1 2 2 8 1.999E8 7.31 11.14 2 4 324.73 11.14 2 4 332 37.5 4.61 HVO_2383 DNA repair and recombination protein RadB 10.92 1 2 2 7 6.715E7 4.42 10.92 2 3 334.83 10.92 2 4 229 24.6 5.02 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 10.63 1 3 3 7 8.163E7 5.07 7.09 2 3 394.18 10.63 3 4 395 42.4 4.54 HVO_1356 sensor box histidine kinase 10.55 1 3 3 10 1.917E8 2.33 10.55 3 5 397.01 10.55 3 5 550 61.1 4.60 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 10.50 1 2 2 5 2.252E8 4.45 10.50 2 3 152.19 10.50 2 2 219 22.4 4.06 HVO_0658 tRNA pseudouridine(13) synthase TruD 10.37 1 3 3 8 1.267E8 2.09 10.37 3 4 345.73 10.37 3 4 463 50.6 4.70 HVO_1139 squalene synthase 10.34 1 2 2 8 1.257E8 9.04 10.34 2 4 511.83 10.34 2 4 358 39.7 4.54 HVO_C0040 site-specific DNA-methyltransferase (cytosine-specific) 10.34 1 3 3 7 1.231E8 4.41 10.34 3 4 203.47 10.34 3 3 406 45.5 5.08 HVO_1895 KEOPS complex subunit Kae1/Bud32 10.33 1 4 4 9 1.160E8 8.03 10.33 4 5 447.18 9.06 3 4 552 59.0 5.07 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 10.33 1 5 5 12 1.696E8 3.74 10.33 5 6 492.83 10.33 5 6 658 72.1 4.70 HVO_2952 tRNA-splicing endonuclease 10.32 1 2 2 6 4.928E7 4.51 10.32 2 3 205.02 10.32 2 3 339 37.4 4.74 HVO_1716 7-cyano-7-deazaguanine synthase 10.25 1 2 2 6 8.549E7 0.00 10.25 2 3 220.49 10.25 2 3 244 26.8 4.42 47132620 keratin 2a [Homo sapiens] 10.17 1 3 7 32 7.373E8 31.79 10.17 7 17 1986.38 10.17 7 15 639 65.4 8.00 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 10.03 1 3 3 6 3.649E7 0.00 10.03 3 3 135.32 10.03 3 3 379 41.7 4.83 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 5 5.032E8 7.33 10.00 2 5 190 21.0 4.74 HVO_2266 hypothetical protein 9.94 1 4 4 10 7.885E7 1.93 9.94 4 5 262.11 9.94 4 5 493 56.7 4.54 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 9.94 1 4 4 13 1.452E8 8.60 9.94 4 7 410.06 8.36 3 6 634 66.1 4.54 HVO_3014 origin-associated GTP-binding protein OapA 9.86 1 2 2 4 1.420E8 4.68 9.86 2 2 225.36 9.86 2 2 213 24.0 5.01 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 9.79 1 3 3 6 1.629E8 3.79 9.79 3 3 252.55 9.79 3 3 337 35.9 4.69 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 9.76 1 3 3 9 1.121E8 2.93 9.76 3 4 414.47 9.76 3 5 420 45.0 4.86 HVO_1323 "shikimate kinase, archaeal-type" 9.69 1 2 2 12 5.675E8 8.15 9.69 2 6 684.16 9.69 2 6 289 29.5 4.30 HVO_1098 diaminopimelate decarboxylase 9.64 1 3 3 9 2.371E8 7.88 6.51 2 4 494.44 9.64 3 5 415 44.4 5.02 HVO_1676 transcription initiation factor TFB 9.64 1 0 2 6 5.811E8 8.04 9.64 2 3 412.95 9.64 2 3 332 37.3 5.49 HVO_0100 NMD3 family protein 9.60 1 3 3 5 8.390E7 1.69 6.40 2 2 155.29 9.60 3 3 375 41.6 4.46 HVO_C0001 Orc1-type DNA replication protein 9.56 1 4 4 9 1.345E8 6.39 9.56 4 5 308.98 9.56 4 4 408 45.2 4.97 HVO_2501 alpha/beta hydrolase fold protein 9.49 1 2 2 4 3.605E7 2.05 9.49 2 2 150.88 9.49 2 2 316 35.3 5.72 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 9.43 1 3 3 5 1.441E8 2.88 9.43 3 3 204.63 5.39 2 2 297 32.3 3.98 HVO_1501 DeoR family transcription regulator GlpR 9.41 1 2 2 6 5.340E7 6.43 9.41 2 3 320.96 9.41 2 3 255 28.0 4.97 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 9.30 1 4 4 24 3.834E8 12.55 8.14 3 11 1152.95 9.30 4 13 430 44.2 4.37 HVO_0768 radical SAM domain protein 9.20 1 2 2 4 6.267E7 0.00 9.20 2 2 127.67 9.20 2 2 565 62.0 4.84 HVO_2716 acyl-CoA dehydrogenase 9.19 1 2 2 7 2.322E7 2.37 9.19 2 4 215.52 9.19 2 3 381 41.3 4.65 HVO_0541 aconitate hydratase 9.06 1 5 5 19 3.856E8 10.33 9.06 5 10 675.55 9.06 5 9 938 102.1 4.40 HVO_1080 conserved hypothetical protein 9.04 1 2 2 6 3.405E8 0.00 9.04 2 3 318.27 9.04 2 3 188 21.1 4.31 HVO_A0328 2-keto-3-deoxygluconate kinase 8.81 1 2 3 13 1.277E8 1.64 8.81 3 7 420.58 8.81 3 6 318 34.0 4.60 HVO_0724 ArsA family ATPase 8.80 1 2 2 3 1.824E7 190.03 8.80 2 3 409 43.9 4.22 HVO_0680 (S)-3-O-geranylgeranylglyceryl phosphate synthase 1 8.75 1 2 2 2 0.000E0 51.88 8.75 2 2 240 26.5 4.17 HVO_0069 sulfatase 8.74 1 4 4 6 9.756E7 4.62 3.88 2 3 237.62 6.21 3 3 515 57.4 4.35 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 8.74 1 3 3 5 1.038E8 2.10 5.69 2 2 171.79 8.74 3 3 492 52.1 4.83 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 8.67 1 2 2 5 9.490E7 0.00 8.67 2 2 225.15 8.67 2 3 323 34.9 5.24 HVO_2227 siroheme decarboxylase AhbA 8.65 1 2 2 6 5.674E7 2.42 8.65 2 3 223.66 8.65 2 3 347 39.1 4.69 HVO_2427 replication factor C large subunit 8.61 1 4 4 13 1.595E8 5.83 8.61 4 7 494.85 8.61 4 6 488 53.4 4.67 HVO_1387 enoyl-CoA hydratase 8.56 1 2 2 4 4.261E7 2.00 8.56 2 2 118.19 8.56 2 2 257 27.5 4.51 HVO_B0001 Orc1-type DNA replication protein 8.54 1 3 3 5 8.742E7 5.86 8.54 3 3 258.95 6.34 2 2 410 45.8 5.33 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 8.50 1 3 3 6 1.051E8 3.69 8.50 3 3 261.60 8.50 3 3 459 50.5 4.63 HVO_1096 succinyl-diaminopimelate desuccinylase 8.49 1 1 2 3 6.341E7 205.26 8.49 2 3 365 37.7 4.40 HVO_2456 anthranilate phosphoribosyltransferase 8.46 1 2 2 2 2.513E9 189.70 8.46 2 2 331 33.8 4.35 HVO_0681 DNA topoisomerase I 8.45 1 6 6 21 8.777E7 8.82 5.60 4 9 1158.58 8.45 6 12 840 93.6 4.58 HVO_2880 probable peptide chain release factor pelota 8.43 1 2 2 6 3.411E8 1.67 8.43 2 3 290.30 8.43 2 3 356 39.3 4.63 HVO_1055 TrkA domain protein 8.41 1 2 2 5 4.110E7 3.72 8.41 2 2 281.20 8.41 2 3 226 24.4 4.39 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 8.41 1 2 2 4 1.538E8 0.00 8.41 2 2 196.38 8.41 2 2 345 36.9 4.68 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 8.36 1 3 3 12 8.704E8 10.41 8.36 3 6 700.27 8.36 3 6 299 32.0 4.53 HVO_1097 diaminopimelate epimerase 8.33 1 2 2 10 1.788E8 9.83 8.33 2 5 576.29 8.33 2 5 288 29.9 4.48 HVO_B0182 deoxyhypusine synthase 8.33 1 2 2 4 9.183E7 2.21 8.33 2 2 160.32 8.33 2 2 324 35.6 4.30 HVO_1629 conserved hypothetical protein 8.29 1 3 3 5 1.955E8 0.00 8.29 3 3 152.88 6.97 2 2 531 56.3 4.69 HVO_B0038A D-xylonate dehydratase 8.25 1 1 3 16 8.907E8 11.60 8.25 3 9 601.49 8.25 3 7 412 45.5 4.55 HVO_2160 conserved hypothetical protein 8.20 1 12 12 59 7.704E8 55.13 8.20 12 30 3418.65 8.20 12 29 2257 232.7 3.92 HVO_1309 peptidase M24 family protein 8.18 1 3 3 12 2.243E7 12.69 8.18 3 6 713.17 8.18 3 6 391 42.1 4.36 HVO_2648 phosphoglycerate dehydrogenase 8.15 1 2 2 7 1.454E8 5.81 8.15 2 4 280.11 8.15 2 3 319 34.2 4.64 HVO_0552 DNA mismatch repair protein MutS 8.12 1 6 6 19 3.330E8 8.05 8.12 6 9 843.10 8.12 6 10 924 99.2 4.65 HVO_0322 MinD/ParA domain protein 8.09 1 2 2 6 8.371E7 5.32 8.09 2 3 377.05 8.09 2 3 581 58.8 3.70 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 8.07 1 5 5 18 2.526E8 12.59 8.07 5 9 824.26 8.07 5 9 706 73.3 4.39 HVO_1914 acetyl-CoA C-acyltransferase 7.96 1 2 2 7 4.246E7 7.16 7.96 2 3 424.92 7.96 2 4 377 39.9 4.41 HVO_2908 dihydropteroate synthase 7.92 1 2 2 6 4.482E7 6.38 7.92 2 3 259.62 7.92 2 3 379 40.8 4.53 HVO_1058 TrkA domain protein 7.87 1 3 3 11 6.220E8 6.33 7.87 3 6 437.87 6.07 2 5 445 47.7 4.35 HVO_0782 nicotinamide-nucleotide adenylyltransferase 7.73 1 1 2 2 5.582E5 101.73 7.73 2 2 181 20.4 4.61 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 7.72 1 2 2 9 1.755E8 8.43 7.72 2 4 644.63 7.72 2 5 324 36.6 4.68 HVO_1710 alpha amylase 7.68 1 4 4 12 8.126E7 3.61 7.68 4 6 475.06 4.58 3 6 677 75.0 4.45 HVO_1625 conserved hypothetical protein 7.65 1 3 3 8 1.486E8 7.57 7.65 3 4 398.47 7.65 3 4 654 70.1 4.04 HVO_B0055 conserved hypothetical protein 7.56 1 2 2 5 4.539E8 4.16 7.56 2 2 252.31 7.56 2 3 225 23.9 4.69 HVO_0469 AstE family protein 7.55 1 2 2 8 2.531E8 5.60 7.55 2 4 345.30 7.55 2 4 318 33.9 5.85 HVO_A0586 sugar nucleotidyltransferase 7.54 1 2 2 6 1.697E8 4.37 7.54 2 3 275.17 7.54 2 3 411 43.7 4.69 HVO_A0156 acyl-CoA synthetase 7.53 1 0 4 10 2.174E8 5.58 7.53 4 5 355.77 7.53 4 5 664 74.0 4.40 HVO_A0257 Orc1-type DNA replication protein 7.53 1 3 3 8 1.779E7 0.00 7.53 3 4 167.12 7.53 3 4 425 48.0 4.94 HVO_2467 NADPH:quinone reductase 7.48 1 2 2 12 2.758E8 6.56 7.48 2 6 501.86 7.48 2 6 321 33.0 4.51 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 7.47 1 3 3 12 1.215E8 7.32 7.47 3 6 539.64 7.47 3 6 482 50.6 4.31 HVO_1683 4-alpha-glucanotransferase 7.46 1 4 4 10 1.085E8 1.73 7.46 4 5 381.68 7.46 4 5 496 56.3 4.45 HVO_0180 23S rRNA (uridine-2'-O-) methyltransferase 7.34 1 2 2 2 1.274E8 124.49 7.34 2 2 259 28.3 4.70 HVO_0448 imidazoleglycerol-phosphate synthase subunit HisH 7.31 1 2 2 4 0.000E0 2.67 7.31 2 2 228.76 7.31 2 2 219 23.4 4.23 HVO_0470 threonine synthase 7.08 1 2 2 2 5.141E7 146.77 7.08 2 2 367 39.2 4.59 HVO_0551 DNA mismatch repair protein MutL 7.07 1 4 4 7 1.226E8 3.29 5.99 3 3 291.98 7.07 4 4 735 78.7 4.50 HVO_0431 HAD superfamily hydrolase 7.04 1 2 2 6 3.579E7 5.86 7.04 2 3 255.17 7.04 2 3 284 30.4 4.26 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 7.03 1 4 4 13 4.244E8 13.19 7.03 4 7 694.56 5.56 3 6 612 67.3 4.16 HVO_2158 malic enzyme (NADP) 6.79 1 0 3 12 6.808E8 9.31 6.79 3 6 612.48 6.79 3 6 751 81.4 4.55 HVO_2001 tRNA-guanine(15) transglycosylase 6.78 1 2 2 11 4.791E7 12.84 6.78 2 5 533.89 6.78 2 6 516 56.3 4.59 HVO_0464 threonine ammonia-lyase 6.70 1 2 2 4 5.904E7 0.00 6.70 2 2 159.59 6.70 2 2 403 43.7 4.72 HVO_B0057 precorrin-3B C17-methyltransferase 6.69 1 2 2 8 2.916E8 10.02 6.69 2 4 692.04 6.69 2 4 344 36.3 4.31 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 6.67 1 2 2 6 9.984E7 7.51 6.67 2 3 389.98 6.67 2 3 360 39.5 4.31 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 6.67 1 2 2 6 5.119E7 0.00 6.67 2 3 92.43 6.67 2 3 345 37.0 3.95 HVO_1656 YyaL family protein 6.40 1 4 4 8 2.995E7 2.51 6.40 4 4 395.62 6.40 4 4 703 77.3 4.49 HVO_1812 conserved hypothetical protein 6.40 1 2 2 2 3.650E7 80.79 6.40 2 2 375 40.5 4.50 HVO_0662 HTH domain protein / thiamine-phosphate synthase 6.35 1 2 2 8 4.853E7 5.76 6.35 2 4 499.52 6.35 2 4 299 31.9 4.44 HVO_A0150 TrmB family transcription regulator 6.21 1 2 2 4 1.925E8 5.21 6.21 2 2 266.64 6.21 2 2 354 39.0 4.63 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 6.20 1 2 2 6 2.370E7 7.20 6.20 2 3 320.32 6.20 2 3 403 41.1 4.73 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 6.20 1 2 2 11 6.359E7 7.02 6.20 2 5 692.19 6.20 2 6 516 56.7 4.89 HVO_0741 DNA-directed DNA polymerase X 6.19 1 2 2 6 1.301E8 3.95 6.19 2 3 147.44 6.19 2 3 582 62.6 4.44 HVO_0048 argininosuccinate lyase 6.15 1 2 2 4 1.703E8 360.61 6.15 2 4 488 50.8 4.53 HVO_0670 glutathione S-transferase 6.13 1 2 2 2 0.000E0 2.00 6.13 2 2 326 38.1 4.56 HVO_A0092 acyl-CoA dehydrogenase 6.04 1 2 2 6 3.244E7 1.75 6.04 2 3 117.59 6.04 2 3 381 42.2 4.83 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 5.95 1 2 2 6 1.387E8 2.14 5.95 2 3 252.12 5.95 2 3 353 36.7 4.65 HVO_0945 ba3-type terminal oxidase subunit I 5.94 1 2 2 2 5.906E6 0.00 5.94 2 2 589 64.3 6.71 HVO_0194 Orc1-type DNA replication protein 5.88 1 2 2 2 1.902E8 114.11 5.88 2 2 374 42.2 4.94 HVO_2187 CHP01210 family protein 5.83 1 2 2 2 6.874E7 0.00 5.83 2 2 360 40.0 4.58 HVO_C0057 Orc1-type DNA replication protein 5.74 1 2 2 6 3.994E7 0.00 5.74 2 3 168.32 5.74 2 3 418 46.3 5.02 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 5.73 1 0 3 11 1.073E8 10.79 5.73 3 6 615.04 5.73 3 5 384 42.4 5.40 HVO_2581 quinolinate synthase A 5.71 1 2 2 9 2.457E8 0.00 5.71 2 4 391.40 5.71 2 5 385 42.0 4.41 21961227 Keratin 6B [Homo sapiens] 5.67 1 0 4 16 1.073E8 12.41 5.67 4 7 761.44 5.67 4 9 564 60.0 8.00 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 5.67 1 2 2 3 1.058E8 4.33 5.67 2 3 388 41.9 4.35 HVO_1465 naphthoate synthase 5.57 1 2 2 4 1.204E8 2.24 5.57 2 2 158.74 5.57 2 2 305 33.9 4.83 HVO_1725 Orc1-type DNA replication protein 5.49 1 2 2 6 2.136E7 4.68 5.49 2 3 276.43 5.49 2 3 401 44.5 5.19 HVO_0639 AAA-type ATPase (MoxR subfamily) 5.38 1 2 2 6 4.431E7 1.78 5.38 2 3 281.81 5.38 2 3 316 34.7 4.89 HVO_0968 NADH dehydrogenase-like complex subunit CD 5.32 1 0 3 12 7.491E8 13.96 5.32 3 6 693.42 5.32 3 6 564 63.3 4.60 HVO_A0180 SMC-like protein Sph1 5.23 1 1 2 2 2.256E9 100.57 5.23 2 2 593 66.4 4.58 HVO_1113 "FtsZ family protein, type III" 5.14 1 0 2 12 8.455E8 8.07 5.14 2 6 539.37 5.14 2 6 389 40.8 4.89 HVO_1340 "probable glycosyltransferase, type 1" 5.07 1 2 2 2 9.371E7 3.54 5.07 2 2 375 41.0 4.42 HVO_2321 bacterial-type DNA primase DnaG 4.87 1 2 2 6 1.028E8 4.30 4.87 2 3 299.18 4.87 2 3 472 49.4 4.36 HVO_1375 O-succinylbenzoic acid--CoA ligase 4.72 1 2 2 6 8.947E7 6.47 4.72 2 3 262.97 4.72 2 3 614 64.7 4.28 HVO_1711 glucoamylase 4.70 1 5 5 12 9.355E7 7.18 4.70 5 7 628.54 3.64 4 5 1511 166.1 4.64 HVO_A0551 acyl-CoA synthetase 4.65 1 2 2 2 7.479E6 0.00 4.65 2 2 538 59.6 4.65 HVO_0001 Orc1-type DNA replication protein 4.61 1 2 2 5 3.748E7 2.29 4.61 2 3 290.89 4.61 2 2 564 62.1 4.39 HVO_1723 DNA repair helicase Rad25 4.60 1 2 2 4 1.588E7 4.66 4.60 2 2 245.99 4.60 2 2 695 76.8 4.69 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 4.52 1 2 2 6 2.172E8 5.25 4.52 2 3 449.12 4.52 2 3 398 43.4 4.37 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 4.18 1 2 2 5 1.486E8 0.00 4.18 2 2 208.78 4.18 2 3 838 89.1 4.65 HVO_2004 serine O-acetyltransferase 4.18 1 1 2 11 8.465E8 1.64 4.18 2 5 398.38 4.18 2 6 287 31.9 5.21 HVO_0191 DNA mismatch repair protein MutS 4.07 1 1 2 2 4.226E5 0.00 4.07 2 2 664 70.7 4.46 HVO_B0143 receiver/sensor box histidine kinase 4.02 1 2 2 8 1.055E8 1.79 4.02 2 4 358.67 4.02 2 4 597 66.0 4.41 HVO_0220 ATP-dependent DNA helicase MCM 3.99 1 3 3 10 7.666E7 9.73 3.99 3 5 320.99 3.99 3 5 702 78.8 4.73 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 3.90 1 0 3 11 1.073E8 10.79 3.90 3 6 615.04 3.90 3 5 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 3.90 1 0 3 11 1.073E8 10.79 3.90 3 6 615.04 3.90 3 5 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 3.90 1 0 3 11 1.073E8 10.79 3.90 3 6 615.04 3.90 3 5 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 3.90 1 0 3 11 1.073E8 10.79 3.90 3 6 615.04 3.90 3 5 564 60.0 7.72 HVO_1685 conserved hypothetical protein 3.86 1 2 2 6 1.303E8 0.00 3.86 2 3 209.06 3.86 2 3 492 54.5 5.74 HVO_3000 DNA ligase (NAD) 3.86 1 2 2 3 1.229E9 281.61 3.86 2 3 699 75.8 4.50 4557890 keratin 5 [Homo sapiens] 3.73 1 0 3 11 1.073E8 10.79 3.73 3 6 615.04 3.73 3 5 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 3.73 1 0 3 11 1.073E8 10.79 3.73 3 6 615.04 3.73 3 5 590 62.4 8.06 HVO_B0256 aldehyde ferredoxin oxidoreductase 3.60 1 2 2 5 8.139E7 5.09 3.60 2 3 114.19 3.60 2 2 555 59.9 4.55 HVO_0014 ATP-dependent DNA helicase Hel308a 3.51 1 2 2 12 1.575E8 6.70 3.51 2 6 491.72 3.51 2 6 827 90.3 4.67 31074631 keratin 1b [Homo sapiens] 3.46 1 0 2 14 5.406E8 14.29 3.46 2 8 844.21 3.46 2 6 578 61.8 5.97 31559823 keratin 25D [Homo sapiens] 3.45 1 0 2 5 3.041E8 3.78 3.45 2 5 464 50.6 5.47 HVO_1354 DNA mismatch repair protein MutS 3.45 1 2 2 3 5.903E7 3.87 3.45 2 3 580 62.1 4.56 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 3.39 1 0 2 5 3.041E8 3.78 3.39 2 5 472 51.6 5.16 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 3.38 1 0 2 5 3.041E8 3.78 3.38 2 5 473 51.2 5.05 HVO_0689 chromosome segregation protein Smc 3.31 1 2 2 2 4.670E7 95.18 3.31 2 2 1240 138.1 4.39 HVO_1228 halocyanin 3.29 1 2 2 6 4.676E7 0.00 3.29 2 3 194.99 3.29 2 3 821 83.7 4.17 HVO_B0154 receiver/sensor box histidine kinase 2.69 1 2 2 3 0.000E0 1.97 2.69 2 3 1301 144.1 4.39 HVO_C0043 conserved hypothetical protein 2.57 1 2 2 4 3.348E7 0.00 2.57 2 2 153.42 2.57 2 2 661 73.8 4.75 HVO_0854 DNA double-strand break repair ATPase Rad50 2.35 1 2 2 8 1.192E7 7.05 2.35 2 4 447.15 2.35 2 4 893 100.0 4.58 HVO_1953 receiver/sensor/bat box HTH-10 family transcription regulator (nonfunctional) 2.23 1 2 2 2 5.648E6 0.00 2.23 2 2 1077 115.6 4.69 HVO_A0550 receiver/sensor box histidine kinase 2.15 1 2 2 4 2.017E7 3.37 2.15 2 2 144.84 2.15 2 2 885 95.9 4.46 4504919 keratin 8 [Homo sapiens] 2.07 1 0 2 9 4.614E7 7.86 2.07 2 5 438.62 2.07 2 4 483 53.7 5.59 HVO_C0042 helicase domain protein 1.49 1 2 2 4 1.684E7 2.29 1.49 2 2 171.65 1.49 2 2 1274 144.4 4.67