Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0359 translation elongation factor aEF-1 alpha subunit 79.57 1 19 23 1208 9.203E10 1192.26 79.57 22 542 95633.75 79.57 23 666 421 45.7 4.73 HVO_0880 conserved hypothetical protein 77.52 1 27 27 312 6.309E9 339.68 77.52 27 158 22058.79 77.52 27 154 307 36.3 4.74 HVO_0356 translation elongation factor aEF-2 75.93 1 45 45 924 3.252E10 802.03 73.45 42 458 53931.56 75.93 45 466 727 80.4 4.73 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 72.57 1 19 19 328 1.519E10 268.15 72.57 19 160 20114.37 72.57 19 168 350 37.6 4.54 HVO_0859 FeS assembly ATPase SufC 67.77 1 17 17 147 5.759E9 108.92 63.79 15 72 8494.66 65.45 16 75 301 33.4 4.35 HVO_2862 serine hydroxymethyltransferase 66.99 1 16 16 270 1.130E10 217.20 57.35 14 135 15461.28 66.99 16 135 415 44.3 4.53 HVO_0677 aspartate--tRNA ligase 65.90 1 18 18 276 9.049E9 224.63 65.90 18 135 15373.11 65.90 18 141 434 48.7 4.50 HVO_2544 30S ribosomal protein S5 64.49 1 12 12 71 1.016E10 52.08 61.68 11 36 4116.23 62.15 11 35 214 23.3 9.29 HVO_0433 F420H2:NADP oxidoreductase 64.41 1 8 8 35 1.690E9 34.94 64.41 8 17 2082.01 64.41 8 18 222 23.3 4.72 HVO_0133 thermosome subunit 1 63.57 1 23 25 176 5.146E9 128.07 62.32 24 84 11069.94 52.68 22 92 560 58.9 4.25 HVO_0025 thiosulfate sulfurtransferase 61.89 1 11 11 278 1.602E10 247.98 59.44 10 139 14488.62 61.89 11 139 286 32.1 4.28 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 61.34 1 6 6 42 1.829E9 33.25 50.52 5 16 3065.35 61.34 6 26 194 20.7 4.12 HVO_1507 acetolactate synthase small subunit 60.55 1 10 10 45 7.315E8 42.52 60.55 10 22 2904.93 60.55 10 23 218 23.7 4.94 HVO_2900 fumarate hydratase 59.70 1 16 16 154 7.596E9 153.28 59.70 16 77 9887.57 52.03 15 77 469 50.1 4.78 HVO_1637 FKBP-type peptidylprolyl isomerase 59.48 1 10 11 117 6.345E9 87.78 50.98 10 52 8449.08 59.48 11 65 306 33.8 3.76 HVO_2783 30S ribosomal protein S4 59.43 1 11 11 72 5.135E9 56.24 54.86 9 34 4620.51 59.43 11 38 175 20.1 5.24 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 59.32 1 15 15 214 1.192E10 192.67 59.32 15 106 12775.05 59.32 15 108 381 41.0 4.23 HVO_1921 serine--tRNA ligase 59.13 1 21 21 113 2.836E9 93.76 59.13 21 56 6694.10 59.13 21 57 460 52.0 4.46 HVO_0348 DNA-directed RNA polymerase subunit B' 58.95 1 27 27 183 2.561E9 147.93 58.95 27 90 9533.41 58.95 27 93 609 67.7 4.92 HVO_0055 CBS domain protein 58.80 1 11 11 79 4.203E9 61.61 58.80 11 39 4667.79 58.80 11 40 284 30.8 4.27 HVO_0175 DNA polymerase sliding clamp 58.70 1 8 8 163 5.429E9 124.58 58.70 8 78 8538.65 58.70 8 85 247 26.7 4.39 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 58.59 1 16 16 170 8.345E9 212.69 58.59 16 83 14007.61 58.59 16 87 384 41.4 4.41 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 58.01 1 12 12 64 1.950E9 56.26 58.01 12 33 4098.90 52.31 11 31 281 30.6 4.59 HVO_1145 30S ribosomal protein S1e 57.73 1 12 12 80 3.097E9 88.74 57.73 12 37 6188.00 57.73 12 43 220 24.8 4.86 HVO_1273 inosine-5'-monophosphate dehydrogenase 56.63 1 20 20 190 6.832E9 148.39 54.02 19 93 11426.04 56.63 20 97 498 53.3 4.55 HVO_2588 isocitrate dehydrogenase (NADP) 56.09 1 21 21 175 1.431E10 180.55 51.31 19 83 12515.02 56.09 21 92 419 45.8 4.59 HVO_0104 DNA repair and recombination protein RadA 55.98 1 14 14 85 4.673E9 54.77 50.73 13 39 5786.51 55.98 14 46 343 37.3 4.64 HVO_0329 branched-chain amino acid aminotransferase 55.77 1 14 14 104 4.225E9 104.12 55.77 14 51 6638.70 55.77 14 53 312 35.0 4.58 HVO_0869 glutamate synthase large subunit 55.66 1 60 61 357 4.104E9 318.33 55.20 60 176 22509.99 55.66 61 181 1511 163.8 4.70 HVO_2015 conserved hypothetical protein 55.36 1 11 11 169 1.724E10 189.53 55.36 11 83 12871.12 55.36 11 86 345 37.7 4.25 HVO_2779 50S ribosomal protein L18e 54.31 1 5 5 15 4.348E7 6.08 54.31 5 8 543.52 31.03 4 7 116 12.7 8.50 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 54.05 1 20 20 138 4.968E9 120.83 47.64 19 68 8416.24 54.05 20 70 592 66.6 4.61 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 54.03 1 12 12 36 9.248E8 19.31 43.84 11 17 1424.52 54.03 12 19 422 43.6 4.72 HVO_0317 A-type ATP synthase subunit B 53.85 1 15 16 161 1.076E10 177.64 52.35 15 78 12655.12 53.85 16 83 468 51.9 4.25 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 53.16 1 7 7 51 2.889E9 46.48 53.16 7 26 3512.68 39.47 6 25 190 20.6 4.30 HVO_2968 phosphoglycerate dehydrogenase 52.95 1 19 19 207 1.190E10 225.85 52.95 19 100 15893.77 52.95 19 107 525 55.3 4.36 HVO_0778 thermosome subunit 3 52.86 1 20 22 170 3.402E9 198.92 52.86 22 85 12644.20 52.86 22 85 524 55.2 4.59 HVO_2889 RecJ domain protein 52.40 1 27 28 237 9.731E9 217.76 50.48 26 114 14689.31 52.40 28 123 729 79.1 4.37 HVO_0347 DNA-directed RNA polymerase subunit B'' 52.02 1 25 25 144 2.993E9 96.38 48.94 23 68 7480.27 52.02 25 76 521 58.9 5.00 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 51.92 1 11 11 266 1.130E10 211.46 51.92 11 136 14803.81 51.92 11 130 312 34.5 4.98 HVO_0850 proteasome-activating nucleotidase 51.85 1 13 14 68 1.918E9 46.72 46.67 13 29 3427.00 51.85 14 39 405 45.6 4.60 HVO_2724 beta-lactamase domain protein 51.56 1 17 17 177 6.659E9 149.72 51.56 17 85 9795.59 51.56 17 92 450 50.1 5.40 HVO_0861 SufB domain protein 51.49 1 15 15 152 6.421E9 149.79 51.49 15 76 11580.89 51.49 15 76 402 44.7 4.23 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 25 1.565E9 8.72 37.91 4 10 1119.64 50.33 5 15 153 16.9 4.21 HVO_2519 conserved hypothetical protein 50.26 1 14 14 60 4.201E9 53.54 45.55 13 29 3973.21 48.95 13 31 382 40.7 4.35 HVO_2413 translation elongation factor aEF-1 alpha subunit 50.24 1 11 16 105 1.478E10 80.99 47.14 14 53 5851.37 48.57 14 52 420 45.6 4.75 HVO_0860 SufB domain protein 50.21 1 18 19 181 9.217E9 150.91 47.06 17 88 11220.48 48.53 18 93 476 53.2 4.69 HVO_2552 30S ribosomal protein S4e 50.20 1 9 9 176 2.173E10 151.55 50.20 9 88 8983.99 50.20 9 88 247 26.6 4.58 HVO_2861 conserved hypothetical protein 50.18 1 11 11 46 1.080E9 32.80 50.18 11 23 2103.99 40.73 10 23 275 29.1 4.27 HVO_1132 adenylosuccinate synthase 50.11 1 20 20 256 9.997E9 183.79 46.95 19 121 15269.36 50.11 19 135 443 48.2 4.56 HVO_0212 homolog to lactoylglutathione lyase 50.00 1 4 4 17 6.028E8 16.21 50.00 4 9 807.02 43.55 3 8 124 13.5 4.13 HVO_0310 A-type ATP synthase subunit H 50.00 1 2 2 3 2.396E8 174.38 50.00 2 3 110 12.5 4.03 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 50.00 1 4 4 8 1.369E8 924.82 50.00 4 8 134 13.9 4.55 HVO_2621 phosphoenolpyruvate carboxylase 49.83 1 36 36 174 4.360E9 134.65 48.49 35 86 9656.17 47.83 35 88 897 102.3 4.64 HVO_0455 thermosome subunit 2 49.73 1 22 23 195 5.095E9 151.72 49.73 22 95 10823.45 49.73 23 100 557 59.3 4.37 HVO_1082 homolog to orotate phosphoribosyltransferase 49.05 1 8 8 37 1.417E9 25.58 43.81 7 17 2212.76 49.05 8 20 210 22.3 4.42 HVO_2558 30S ribosomal protein S3 48.68 1 13 14 179 8.597E9 150.78 44.41 13 84 13311.70 47.04 13 95 304 33.4 4.06 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 48.61 1 11 11 45 1.722E9 30.10 48.61 10 22 2315.99 47.22 10 23 360 39.6 4.39 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 48.54 1 12 12 40 1.185E9 32.45 35.06 10 19 1914.54 48.54 12 21 445 47.8 4.86 HVO_1858 30S ribosomal protein S19e 48.34 1 4 4 10 6.228E7 0.00 26.49 2 2 553.53 48.34 4 8 151 16.7 4.84 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 48.08 1 10 10 101 3.757E9 99.96 48.08 10 52 6882.29 48.08 10 49 287 31.0 4.73 HVO_0240 Lrp/AsnC family transcription regulator 48.03 1 6 7 30 1.649E9 12.78 48.03 7 15 1308.79 48.03 6 15 152 16.9 4.39 HVO_0581 "cell division protein FtsZ, type II" 47.75 1 13 13 80 2.798E9 76.09 47.75 13 40 5011.17 47.75 13 40 400 42.5 4.75 HVO_0314 A-type ATP synthase subunit C 47.70 1 15 15 83 1.930E9 57.47 43.68 14 42 4739.66 45.69 14 41 348 38.7 4.50 HVO_1541 glycerol kinase 47.65 1 19 19 128 6.429E9 109.15 42.94 17 63 8444.97 46.67 18 65 510 56.7 4.50 HVO_1284 GTP cyclohydrolase III 47.51 1 9 9 31 3.696E8 31.74 47.51 9 15 2006.20 47.51 9 16 261 28.9 4.70 HVO_2646 dihydroxy-acid dehydratase 47.26 1 18 18 136 3.907E9 121.24 47.26 18 67 7511.58 47.26 18 69 584 61.8 4.42 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 47.20 1 10 10 50 1.156E9 48.27 47.20 10 26 2877.68 47.20 10 24 286 31.2 4.54 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 46.94 1 12 12 49 1.112E9 42.01 42.57 11 23 3068.78 46.94 12 26 343 38.4 4.94 HVO_1506 ketol-acid reductoisomerase 46.84 1 10 10 77 1.285E9 62.40 46.84 10 37 4551.90 46.84 10 40 348 37.9 4.34 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 46.59 1 22 22 350 2.545E10 387.80 42.63 20 174 26290.46 46.59 22 176 631 68.4 4.49 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 128 3.988E9 121.04 43.25 7 63 8168.18 46.37 8 65 289 29.8 4.27 HVO_1502 3-isopropylmalate dehydrogenase 46.30 1 12 12 66 3.581E9 70.07 38.58 11 31 5284.20 46.30 12 35 324 33.7 4.23 HVO_0239 glutamine synthetase 46.27 1 16 16 141 9.024E9 97.73 46.27 16 68 7701.88 46.27 16 73 456 50.5 4.56 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 45.92 1 10 10 52 2.085E9 33.77 45.92 10 25 2889.32 45.92 10 27 355 38.2 4.68 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 45.90 1 12 12 59 4.134E9 47.54 40.98 11 27 4106.37 45.90 12 32 305 33.8 4.74 HVO_2191 formyltetrahydrofolate deformylase 45.87 1 11 11 64 2.939E9 50.39 45.87 11 31 3698.62 45.87 11 33 327 36.2 4.63 HVO_0024 thiosulfate sulfurtransferase 45.74 1 8 8 38 1.465E9 20.19 41.09 7 16 2159.94 45.74 8 22 258 28.4 4.30 HVO_0357 ACT domain protein 45.50 1 6 6 19 7.303E8 5.84 40.74 5 10 560.21 45.50 6 9 189 20.2 4.59 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 45.45 1 10 10 55 3.503E9 42.22 40.74 9 27 3026.55 33.00 9 28 297 31.3 4.36 HVO_1300 triosephosphate isomerase 45.33 1 6 6 37 4.254E9 37.61 45.33 6 19 2762.99 24.30 5 18 214 21.3 4.26 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 45.22 1 21 21 199 5.761E9 164.93 45.22 21 99 12434.74 45.22 21 100 586 64.0 4.49 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 45.21 1 6 6 41 2.181E9 34.60 45.21 6 22 2144.89 45.21 6 19 188 20.5 4.60 HVO_0870 proline--tRNA ligase 45.08 1 15 15 70 2.579E9 58.60 42.62 13 33 4557.04 43.85 14 37 488 54.9 4.44 HVO_A0207 CRISPR-associated protein Cas7 44.71 1 8 8 45 1.066E9 49.05 44.71 8 24 2738.38 37.65 7 21 340 38.2 4.54 HVO_1955 aconitate hydratase 44.50 1 24 24 310 1.302E10 324.36 43.73 23 153 21391.08 44.50 24 157 654 70.4 4.45 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 44.02 1 8 8 46 2.053E9 34.56 44.02 8 23 2666.35 44.02 8 23 259 28.0 4.50 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 43.43 1 15 15 108 3.782E9 107.38 40.19 13 50 7111.03 43.43 15 58 525 56.4 4.40 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 43.35 1 17 17 84 2.037E9 60.84 41.73 16 42 4490.60 43.35 17 42 496 55.0 4.53 HVO_2548 50S ribosomal protein L6 43.26 1 5 5 22 3.445E8 24.41 43.26 5 12 1105.62 40.45 4 10 178 19.6 4.68 HVO_0008 aspartate kinase 43.11 1 11 11 67 5.184E9 49.25 35.46 10 34 3091.75 32.65 9 33 392 41.7 4.46 HVO_1973 conserved hypothetical protein 43.11 1 4 4 18 3.145E8 16.51 43.11 4 9 973.09 43.11 4 9 167 18.1 4.36 HVO_1091 proteasome alpha subunit 42.86 1 11 11 65 2.835E9 60.12 42.86 11 33 4202.48 36.90 9 32 252 27.6 4.56 HVO_2487 aspartate-semialdehyde dehydrogenase 42.73 1 8 8 88 7.161E9 56.66 42.73 8 46 4029.22 42.73 8 42 344 36.6 4.41 HVO_1545 dihydroxyacetone kinase subunit DhaL 42.67 1 8 8 55 3.023E9 46.57 42.67 8 27 3045.81 42.67 8 28 232 24.8 4.48 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 42.56 1 11 11 32 6.926E8 12.78 35.71 10 15 1369.21 42.56 11 17 336 38.0 4.61 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 42.50 1 10 10 51 3.688E9 40.89 42.50 10 25 2830.36 42.50 10 26 280 30.1 4.44 HVO_0480 phosphoglycerate kinase 42.14 1 13 13 69 2.729E9 61.82 34.41 12 34 4585.18 42.14 13 35 401 43.6 4.37 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 42.11 1 9 9 53 1.354E9 50.17 42.11 9 26 3304.88 42.11 9 27 266 27.8 4.84 HVO_2981 uracil phosphoribosyltransferase 42.04 1 7 7 25 2.606E9 9.38 34.51 5 10 1021.92 42.04 7 15 226 24.5 4.49 HVO_2969 threonine synthase 42.00 1 12 12 80 4.736E9 63.99 42.00 12 39 4757.11 42.00 12 41 419 44.4 4.49 HVO_0806 pyruvate kinase 41.88 1 17 17 100 4.347E9 111.09 40.51 16 48 7218.04 41.88 17 52 585 62.0 4.54 HVO_0980 NADH dehydrogenase-like complex subunit CD 41.83 1 13 17 81 2.333E9 56.61 39.50 16 40 3888.72 41.83 17 41 557 63.4 4.53 HVO_0809 methionine--tRNA ligase 41.76 1 22 22 103 1.585E9 79.04 41.76 22 51 5398.22 37.30 21 52 740 81.9 4.37 HVO_0316 A-type ATP synthase subunit A 41.64 1 18 18 174 8.067E9 165.48 41.64 18 89 11190.67 41.64 18 85 586 64.5 4.25 HVO_0789 tryptophan synthase alpha subunit 41.52 1 7 7 35 5.707E8 24.74 41.52 7 17 1987.69 41.52 7 18 277 29.6 4.21 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 41.47 1 10 11 37 5.345E8 27.31 41.47 11 18 2030.68 41.47 11 19 340 38.8 4.58 HVO_1084 adenylosuccinate lyase 41.47 1 13 13 47 1.025E9 35.17 40.39 12 23 2323.38 41.47 13 24 463 50.8 4.70 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 41.37 1 16 16 55 7.226E8 52.92 36.74 15 27 2580.83 41.37 16 28 626 67.6 4.65 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 41.34 1 7 7 26 7.114E8 21.43 22.05 4 11 1273.17 41.34 7 15 254 26.9 4.42 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 41.31 1 11 11 67 2.016E9 41.00 37.45 10 31 3987.03 41.31 11 36 259 29.9 4.36 HVO_A0205 CRISPR-associated endoribonuclease Cas6 41.18 1 10 10 57 7.149E8 53.45 41.18 10 28 3621.93 41.18 10 29 272 31.0 5.44 HVO_0046 putative glutamate--argW ligase 40.89 1 9 9 48 1.906E9 52.58 40.89 9 24 3251.28 40.89 9 24 291 31.9 4.87 HVO_2756 50S ribosomal protein L10 40.80 1 10 10 53 2.816E9 41.67 39.08 9 27 3019.13 38.79 9 26 348 36.9 3.99 HVO_0354 30S ribosomal protein S7 40.69 1 6 6 24 1.299E9 24.51 40.69 6 12 1363.32 40.69 6 12 204 22.6 5.14 HVO_0203 replication factor C small subunit 40.67 1 10 10 48 9.245E8 23.81 40.67 10 23 2032.01 40.67 10 25 327 36.2 4.51 HVO_1175 DUF2110 family protein 40.44 1 6 6 32 1.491E9 32.64 26.67 4 15 1984.08 40.44 6 17 225 24.4 4.63 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 52 1.860E9 51.74 40.26 5 27 3528.87 40.26 5 25 154 17.5 4.50 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 40.18 1 8 8 89 7.271E8 76.49 40.18 8 45 5177.07 40.18 8 44 336 36.8 4.12 HVO_0353 30S ribosomal protein S12 40.14 1 8 8 42 1.849E9 45.80 40.14 8 21 2429.03 40.14 8 21 142 15.5 9.91 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 40.04 1 10 11 53 1.823E9 45.29 37.86 10 24 2839.04 40.04 11 29 457 48.4 4.35 HVO_2774 enolase 39.85 1 11 11 55 4.326E9 49.89 39.85 11 27 3330.00 39.85 11 28 399 42.0 4.37 HVO_1212 KaiC-type circadian regulator CirA 39.84 1 9 9 41 2.585E9 49.36 37.40 8 20 3594.15 39.84 9 21 246 27.5 4.45 HVO_0999 DRTGG domain protein 39.42 1 10 10 58 1.632E9 48.96 39.42 10 28 2993.18 39.42 10 30 378 39.8 4.44 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 39.40 1 36 36 216 2.204E9 161.15 35.82 31 105 11537.89 35.04 33 111 1033 114.3 4.45 HVO_1590 DnaK-type molecular chaperone Hsp70 39.36 1 21 21 165 5.333E9 128.34 38.24 19 82 10255.26 38.40 20 83 625 67.2 4.18 HVO_0324 arginine--tRNA ligase 39.35 1 20 20 103 2.525E9 89.46 37.99 19 50 6106.98 39.35 20 53 587 65.0 4.35 HVO_1198 UspA domain protein 39.31 1 5 5 16 8.718E8 11.55 39.31 5 8 765.12 39.31 5 8 145 15.6 4.75 HVO_1481 UspA domain protein 39.26 1 5 5 32 1.573E9 24.88 39.26 5 16 1725.17 39.26 5 16 163 17.7 4.40 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 39.23 1 10 10 76 5.190E9 55.22 31.96 9 37 4331.10 39.23 10 39 413 45.8 4.45 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 39.03 1 13 13 51 1.451E9 47.25 37.13 12 26 3079.30 39.03 13 25 474 53.4 4.59 HVO_0313 A-type ATP synthase subunit E 38.66 1 5 5 35 9.757E8 31.38 31.44 4 16 2604.34 38.66 5 19 194 22.0 4.31 HVO_0602 3-dehydroquinate dehydratase 38.46 1 6 6 21 2.007E8 13.53 38.46 6 9 809.20 38.46 6 12 247 27.3 4.51 HVO_0694 probable phosphoribosyltransferase 38.40 1 9 9 27 2.653E8 16.42 38.40 9 13 1144.56 38.40 9 14 237 27.0 4.32 HVO_2188 phosphoribosylformylglycinamidine synthase 1 38.39 1 6 6 26 8.977E8 22.03 38.39 6 13 1382.23 38.39 6 13 224 23.9 4.36 HVO_1454 aspartate carbamoyltransferase catalytic subunit 38.16 1 7 7 23 6.194E8 12.38 38.16 7 11 1020.48 38.16 7 12 304 33.7 4.92 HVO_1488 D-gluconate dehydratase 38.11 1 10 12 59 2.432E9 38.28 38.11 12 31 2712.35 38.11 12 28 412 45.8 4.60 HVO_0536 ferritin 38.07 1 3 3 12 5.456E8 14.26 38.07 3 6 526.68 38.07 3 6 176 19.9 4.50 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 61 1.900E9 63.38 35.50 8 31 4117.29 38.05 9 30 431 46.1 4.48 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 38.04 1 5 5 17 6.673E7 10.33 32.61 4 8 909.22 38.04 5 9 184 19.8 5.30 HVO_2419 hydroxymethylglutaryl-CoA synthase 37.98 1 12 12 59 1.639E9 37.78 37.98 12 30 2628.54 37.98 12 29 445 50.1 4.64 HVO_2204 "FtsZ family protein, type III" 37.97 1 9 11 57 3.112E9 50.18 37.97 11 27 3849.71 37.97 11 30 395 42.0 4.68 HVO_1684 threonine--tRNA ligase 37.95 1 22 22 120 3.329E9 97.40 35.46 20 58 7858.52 37.95 22 62 643 73.4 4.45 HVO_0729 inorganic pyrophosphatase 37.85 1 8 8 42 3.449E9 32.97 34.46 7 22 2591.67 37.85 8 20 177 20.4 4.16 HVO_2555 30S ribosomal protein S17 37.72 1 2 2 6 2.204E8 2.24 37.72 2 3 179.34 37.72 2 3 114 12.7 4.81 HVO_0401 UspA domain protein 37.50 1 5 5 22 7.501E8 17.81 37.50 5 11 1240.93 37.50 5 11 152 16.4 4.79 HVO_1031 thioredoxin-disulfide reductase 37.43 1 8 8 42 8.103E8 36.58 37.43 8 21 2086.27 37.43 8 21 342 37.4 4.46 HVO_0358 homoserine dehydrogenase 37.22 1 5 7 22 8.640E8 11.93 29.02 6 11 901.75 37.22 7 11 317 32.4 4.44 HVO_2347 conserved hypothetical protein 37.14 1 4 4 14 2.332E8 9.02 37.14 4 7 793.68 37.14 4 7 140 15.5 4.37 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 37.13 1 6 6 27 5.605E8 18.95 37.13 6 13 1258.11 37.13 6 14 202 22.2 5.11 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 37.01 1 10 10 44 2.472E9 47.15 37.01 10 23 2505.62 29.20 9 21 435 46.9 4.63 HVO_3007 malate dehydrogenase 36.51 1 10 10 217 8.772E9 261.58 36.51 10 108 13311.98 36.51 10 109 304 32.6 4.40 HVO_1295 histidinol-phosphate aminotransferase 36.29 1 8 8 21 3.143E8 13.81 20.78 5 9 938.11 36.29 8 12 361 39.4 4.51 HVO_2773 30S ribosomal protein S2 36.15 1 5 5 69 7.702E9 85.15 30.00 4 33 5673.96 36.15 5 36 260 28.3 4.16 HVO_0138 tyrosine--tRNA ligase 35.98 1 8 8 38 1.424E9 23.26 29.57 7 17 2053.23 35.98 8 21 328 36.1 4.34 HVO_1989 tRNA (pseudouridine(54)-N(1))-methyltransferase 35.86 1 3 3 5 7.178E7 0.00 22.73 2 2 163.56 35.86 3 3 198 21.9 4.79 HVO_1370 gamma-glutamyl phosphate reductase 35.81 1 12 12 42 1.634E9 22.26 25.68 10 20 2084.54 35.81 12 22 444 48.1 4.34 HVO_2726 glutamate--tRNA ligase 35.73 1 16 16 67 1.303E9 38.09 35.73 16 34 2941.15 34.87 15 33 585 65.2 4.58 HVO_1577 conserved hypothetical protein 35.59 1 5 5 18 1.072E9 17.78 35.59 5 9 1146.22 35.59 5 9 177 19.4 4.74 HVO_2813 RimK family protein 35.54 1 13 13 80 3.118E9 75.98 35.54 13 40 5354.48 35.54 13 40 453 49.0 4.73 HVO_0415 repair helicase 35.39 1 16 16 65 1.634E9 59.49 33.93 15 31 4150.91 35.39 16 34 616 69.6 4.70 HVO_B0118 SMC-like protein Sph2 35.09 1 20 20 120 2.643E9 111.71 34.01 19 59 7795.11 34.16 19 61 644 73.8 4.41 HVO_0449 prephenate dehydratase 35.07 1 7 7 26 8.461E8 23.27 32.84 6 12 1735.10 35.07 7 14 268 28.7 4.64 HVO_1504 3-isopropylmalate dehydratase large subunit 34.88 1 13 14 99 5.691E9 102.89 34.88 14 49 7318.03 34.88 14 50 473 51.6 4.55 HVO_2057 sugar nucleotidyltransferase 34.73 1 11 11 49 1.845E9 40.35 34.73 11 25 2377.96 34.73 11 24 357 37.8 4.44 HVO_0206 alanine--tRNA ligase 34.71 1 22 22 92 6.393E8 73.01 33.84 21 45 4832.37 34.71 22 47 922 102.4 4.54 HVO_2013 "FtsZ family protein, type III" 34.52 1 6 6 29 2.511E8 44.13 34.52 6 15 2413.85 34.52 6 14 394 41.5 4.61 HVO_2547 50S ribosomal protein L32e 34.47 1 5 5 23 5.406E8 26.60 21.28 4 11 1872.05 34.47 5 12 235 25.8 4.75 HVO_0167 adenosylhomocysteinase 34.35 1 9 9 38 1.026E9 32.19 30.14 8 16 3134.59 34.35 9 22 428 46.6 4.39 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 34.33 1 17 17 76 1.237E9 50.41 32.17 16 36 4407.20 32.83 16 40 600 65.3 4.68 HVO_1018 RecJ domain protein 33.97 1 17 17 96 1.789E9 90.49 33.18 16 47 5895.06 33.97 17 49 633 69.8 4.58 HVO_0424 ABC-type transport system ATP-binding protein 33.94 1 15 15 58 6.548E8 49.24 28.81 13 26 3147.82 33.94 15 32 604 67.2 4.49 HVO_0161 ATP phosphoribosyltransferase 33.81 1 7 7 28 7.516E8 33.44 33.81 7 14 2067.28 33.81 7 14 281 30.4 4.60 HVO_1690 DHH family phosphoesterase 33.81 1 9 9 37 3.772E8 35.23 33.81 9 18 2104.12 33.81 9 19 485 52.1 4.48 HVO_0717 "cell division protein FtsZ, type I" 33.77 1 11 11 85 6.053E9 90.39 31.93 10 41 6038.89 33.77 11 44 379 39.8 4.40 HVO_0743 probable phosphodiesterase 33.63 1 15 15 71 2.287E9 46.57 33.63 15 33 4088.28 33.63 15 38 449 50.5 4.56 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 33.33 1 12 12 51 1.043E9 44.27 26.44 11 25 2997.65 33.33 12 26 348 38.2 4.32 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 33.19 1 7 7 33 6.594E8 30.33 33.19 7 16 2089.52 33.19 7 17 226 25.5 4.25 HVO_0792 3-dehydroquinate synthase type II 33.16 1 11 11 44 1.261E9 28.84 26.79 9 21 2316.66 33.16 11 23 392 43.1 4.44 HVO_1125 cysteine--tRNA ligase 33.00 1 12 12 54 1.658E9 43.52 30.97 11 25 2828.56 33.00 12 29 494 55.2 4.56 HVO_0393 UvrABC system protein A 32.96 1 23 23 81 5.522E8 51.20 32.96 23 40 3811.52 30.32 22 41 983 108.6 4.82 HVO_1880 conserved hypothetical protein 32.89 1 6 6 16 1.286E8 13.35 22.22 4 7 911.60 32.89 6 9 225 23.8 4.59 HVO_A0206 CRISPR-associated protein Cas8b 32.78 1 17 17 76 1.361E9 58.34 31.52 16 38 3900.71 29.99 16 38 717 79.3 4.60 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 32.69 1 14 14 70 2.424E9 74.18 29.49 12 34 4831.04 32.69 14 36 624 67.6 4.27 HVO_2040 NAD-dependent epimerase/dehydratase 32.35 1 4 8 55 1.588E9 39.50 32.35 8 27 2929.86 32.35 8 28 306 33.8 4.51 HVO_B0061 precorrin-2 C20-methyltransferase 32.34 1 5 5 12 1.803E8 9.20 24.68 4 6 543.49 22.13 4 6 235 25.3 4.63 HVO_0874 beta-lactamase domain protein 32.19 1 16 16 87 2.809E9 86.15 32.19 16 43 6314.88 32.19 16 44 640 71.9 5.14 HVO_1123 thioredoxin-disulfide reductase 32.09 1 9 9 40 1.448E9 15.46 28.08 7 18 2005.48 32.09 9 22 349 37.3 4.32 HVO_1866 uridylate kinase 32.07 1 5 5 22 8.053E8 18.33 32.07 5 11 1124.72 24.47 4 11 237 24.6 4.42 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 31.89 1 13 13 43 6.731E8 40.58 30.05 12 21 2349.07 31.89 13 22 599 65.3 4.51 HVO_0292 replication protein A 31.83 1 8 8 32 6.716E8 15.12 31.83 8 16 1389.74 31.83 8 16 311 34.6 4.31 HVO_0484 50S ribosomal protein L10e 31.82 1 5 5 25 2.667E8 15.01 31.82 5 13 1139.19 31.82 5 12 176 19.8 8.72 HVO_2675 histidinol dehydrogenase 31.78 1 8 8 30 3.967E8 26.46 29.21 7 14 1873.87 30.37 7 16 428 45.4 4.50 HVO_0511 NAD-dependent epimerase/dehydratase 31.68 1 6 6 30 4.280E8 16.18 31.68 6 15 1403.08 31.68 6 15 262 29.3 4.78 HVO_2384 CBS domain protein 31.58 1 12 13 69 3.562E9 48.44 31.58 13 36 3902.61 28.68 11 33 380 42.5 5.01 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 31.50 1 9 9 34 4.054E8 22.00 27.97 8 17 1492.18 31.50 9 17 454 48.5 4.46 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 37 5.866E9 43.60 24.19 2 18 3263.52 31.45 3 19 124 14.2 5.22 HVO_0049 argininosuccinate synthase 31.11 1 11 11 75 3.946E9 50.24 31.11 11 39 3774.47 31.11 11 36 405 44.5 4.34 HVO_2059 NAD-dependent epimerase/dehydratase 30.97 1 7 7 32 9.901E8 27.59 21.29 6 15 1538.39 30.97 7 17 310 34.1 4.40 HVO_2624 CTP synthase 30.97 1 13 13 54 2.243E9 40.03 29.33 12 26 2961.35 29.69 12 28 549 60.8 4.70 HVO_2790 ATP-binding protein Mrp 30.92 1 6 6 18 2.762E8 15.63 30.92 6 9 862.07 30.92 6 9 346 36.8 4.50 HVO_1080 conserved hypothetical protein 30.85 1 4 4 12 4.011E8 1.99 30.85 4 6 454.79 30.85 4 6 188 21.1 4.31 HVO_1657 phosphoribosylamine--glycine ligase 30.84 1 12 12 53 2.207E9 45.20 30.84 12 26 2854.26 30.84 12 27 428 45.5 4.20 HVO_1187 conserved hypothetical protein 30.77 1 4 4 10 5.288E7 7.03 30.77 4 5 311.09 30.77 4 5 143 16.4 4.86 HVO_1576 NAD-dependent epimerase/dehydratase 30.72 1 4 8 47 9.228E8 44.59 30.72 8 23 2867.67 30.72 8 24 306 33.9 4.51 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 30.59 1 11 11 36 1.173E9 23.18 30.59 11 17 1633.02 30.59 11 19 461 50.7 4.73 HVO_0417 metal-dependent carboxypeptidase 30.48 1 12 12 48 6.896E8 42.20 28.09 11 22 2315.60 30.48 12 26 502 57.3 4.42 HVO_0233 ribose-phosphate pyrophosphokinase 30.39 1 5 5 13 6.082E8 7.86 30.39 5 7 388.72 25.80 4 6 283 29.6 4.40 HVO_0109 cysteine desulfurase 30.28 1 10 10 48 7.145E8 53.55 28.17 9 22 3506.04 30.28 10 26 426 46.8 4.56 HVO_2130 IclR family transcription regulator 30.15 1 7 7 33 3.616E8 16.07 26.10 6 15 1929.62 30.15 7 18 272 30.1 5.55 HVO_2336 pyridoxal biosynthesis lyase PdxS 30.13 1 6 6 40 5.488E8 38.00 26.49 5 17 2592.49 30.13 6 23 302 32.5 4.81 HVO_1546 dihydroxyacetone kinase subunit DhaK 30.12 1 9 9 42 2.697E9 33.11 27.71 8 19 2495.27 30.12 9 23 332 34.8 4.22 HVO_1562 proteasome beta subunit 30.04 1 5 5 27 6.374E8 18.75 30.04 5 14 1307.07 30.04 5 13 243 26.0 4.63 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 29.80 1 8 8 36 1.177E9 34.16 29.80 8 18 2210.30 29.80 8 18 453 47.5 4.63 HVO_0041 ornithine carbamoyltransferase 29.77 1 6 6 31 9.117E8 13.72 29.77 6 15 1671.22 29.77 6 16 299 32.7 4.37 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 29.75 1 8 8 34 2.655E8 34.78 29.75 8 17 2095.94 29.75 8 17 363 39.3 4.97 HVO_1854 histidine--tRNA ligase 29.70 1 9 9 43 1.341E9 56.20 29.70 9 22 3066.96 29.70 9 21 431 47.1 4.37 HVO_2913 superoxide dismutase (Mn) 29.65 1 0 3 39 6.810E9 50.81 29.65 3 20 2800.37 29.65 3 19 199 22.3 4.48 HVO_2564 50S ribosomal protein L3 29.59 1 7 7 27 3.134E8 23.80 24.26 6 13 1578.73 29.59 7 14 338 37.2 6.68 HVO_A0475 superoxide dismutase (Mn) 29.50 1 0 3 39 6.810E9 50.81 29.50 3 20 2800.37 29.50 3 19 200 22.4 4.45 HVO_1371 glutamate 5-kinase 29.24 1 5 5 15 1.154E9 12.66 22.59 4 7 981.85 29.24 5 8 301 32.0 4.25 HVO_2549 30S ribosomal protein S8 29.23 1 4 4 16 8.989E8 8.36 29.23 4 8 827.43 29.23 4 8 130 14.1 4.79 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 29.09 1 5 5 17 3.482E8 16.79 29.09 5 8 994.99 29.09 5 9 330 36.3 4.35 HVO_1727 TATA-binding transcription initiation factor 29.03 1 5 6 58 2.575E9 43.63 29.03 6 29 3396.66 29.03 6 29 186 19.9 4.36 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 28.89 1 5 5 26 4.553E8 34.40 28.89 5 13 1939.81 28.89 5 13 270 29.1 4.35 HVO_B0059 cobalt-precorrin 5A hydrolase 28.83 1 6 6 19 3.610E8 13.23 19.94 5 9 883.54 28.83 6 10 326 34.5 4.51 HVO_1572 DNA gyrase subunit B 28.79 1 14 14 49 6.490E8 26.38 28.01 13 24 2085.25 28.79 14 25 639 71.2 4.83 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 28.75 1 10 10 34 4.436E8 22.14 23.47 8 16 1469.76 28.75 10 18 473 50.8 4.58 HVO_0349 DNA-directed RNA polymerase subunit A' 28.69 1 25 25 131 1.560E9 104.95 28.69 25 66 7536.73 28.69 25 65 976 108.8 4.81 HVO_2690 GFO family oxidoreductase 28.69 1 9 9 39 1.447E9 15.52 28.69 9 20 1789.30 26.23 8 19 366 40.0 4.60 17318569 keratin 1 [Homo sapiens] 28.57 1 1 20 117 2.408E9 102.09 28.57 20 58 7689.69 27.64 19 59 644 66.0 8.12 HVO_2912 ThiJ/PfpI domain protein 28.36 1 3 3 10 3.527E7 6.52 28.36 3 5 281.79 28.36 3 5 201 20.9 4.36 HVO_B0018 ParA domain protein 28.22 1 4 4 12 8.765E7 10.45 28.22 4 6 497.11 28.22 4 6 287 31.7 4.74 HVO_2580 L-aspartate oxidase 28.12 1 10 10 38 2.446E8 31.39 28.12 10 19 2037.18 28.12 10 19 537 55.8 4.63 HVO_1338 replication protein A 27.87 1 8 8 31 7.879E8 19.53 27.87 8 15 1465.74 27.87 8 16 427 46.0 4.36 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 27.84 1 9 9 42 2.113E9 37.27 27.84 9 21 2543.08 22.97 8 21 370 41.9 4.48 HVO_1901 translation initiation factor aIF-2 gamma subunit 27.74 1 8 8 60 2.858E9 42.88 27.74 8 30 3240.25 27.74 8 30 411 43.9 4.36 HVO_0388 homolog to ribonuclease R 27.56 1 11 11 35 5.225E8 28.20 27.56 11 18 2060.25 21.64 10 17 439 50.3 4.73 HVO_1306 chorismate synthase 27.53 1 8 8 32 8.006E8 24.87 27.53 8 16 1384.23 27.53 8 16 385 41.9 4.83 HVO_2239 UspA domain protein 27.46 1 4 4 10 6.038E8 6.88 27.46 4 5 607.79 27.46 4 5 142 15.4 4.16 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 27.17 1 0 19 113 2.408E9 100.26 27.17 19 56 7478.70 26.24 18 57 644 66.0 8.12 HVO_0573 endonuclease IV 27.15 1 5 5 20 9.438E8 13.48 27.15 5 9 1074.22 27.15 5 11 291 31.4 4.44 HVO_1654 cysteine synthase 27.12 1 5 5 11 5.431E8 3.65 27.12 5 6 404.78 19.93 4 5 306 32.3 4.32 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 27.00 1 9 9 27 8.687E8 13.40 27.00 9 14 1268.88 24.71 8 13 526 57.2 4.31 HVO_A0406 conserved hypothetical protein 26.91 1 1 7 33 7.906E8 20.36 26.91 7 17 1601.44 26.91 7 16 405 44.4 5.30 HVO_0549 2-keto-3-deoxygluconate kinase 26.88 1 7 8 31 6.541E8 18.17 23.13 7 15 1605.54 25.00 7 16 320 34.1 4.34 HVO_2643 NADPH:quinone reductase 26.88 1 5 5 23 3.856E8 17.90 26.88 5 11 1403.42 26.88 5 12 346 37.2 4.55 HVO_1189 aldehyde dehydrogenase 26.77 1 10 10 53 2.013E9 38.69 25.20 9 26 2696.79 26.77 10 27 508 56.1 4.59 40354192 keratin 10 [Homo sapiens] 26.71 1 0 16 71 5.204E8 54.53 26.71 16 34 3469.58 26.71 16 37 584 58.8 5.16 HVO_1172 NAD-dependent epimerase/dehydratase 26.67 1 5 5 27 1.667E9 21.93 26.67 5 13 1768.87 26.67 5 14 315 34.9 4.34 HVO_0788 tryptophan synthase beta subunit 26.54 1 8 8 40 9.050E8 46.80 22.51 7 19 2579.29 26.54 8 21 422 45.7 4.65 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 26.45 1 12 12 38 8.396E8 20.56 24.74 11 18 1752.54 26.45 12 20 586 63.4 4.70 HVO_2496 adenylate kinase 26.44 1 5 5 18 1.190E9 16.83 26.44 5 9 1138.72 21.63 4 9 208 23.1 4.25 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 26.33 1 11 11 55 9.673E8 43.80 26.33 11 26 2897.20 26.33 11 29 471 51.0 4.48 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 26.31 1 0 16 71 5.204E8 54.53 26.31 16 34 3469.58 26.31 16 37 593 59.5 5.21 HVO_1478 transcription initiation factor TFB 26.18 1 6 8 33 1.176E9 29.58 23.66 7 16 2139.75 26.18 8 17 317 35.7 5.47 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 10 2.604E8 12.89 26.15 3 5 536.97 26.15 3 5 130 13.4 8.56 HVO_2435 peptidase M24 family protein 26.09 1 6 6 20 3.444E8 14.48 26.09 6 9 1019.87 26.09 6 11 368 40.0 4.53 HVO_0519 replication protein A 25.67 1 10 10 49 9.760E8 37.85 22.77 9 24 2922.92 25.67 10 25 483 51.0 4.13 HVO_1459 ThuA family protein 25.63 1 4 4 20 1.642E9 20.43 25.63 4 10 1210.43 25.63 4 10 238 26.8 4.67 HVO_1412 diphosphomevalonate decarboxylase 25.62 1 8 8 37 1.534E9 20.38 25.62 8 18 1737.73 25.62 8 19 324 35.4 4.78 HVO_1510 2-isopropylmalate synthase 25.45 1 7 7 40 2.440E9 31.39 25.45 7 21 1755.99 25.45 7 19 440 47.7 4.82 HVO_0601 homoserine dehydrogenase 25.32 1 5 7 34 9.376E8 32.32 25.32 7 17 2136.41 25.32 7 17 316 32.2 4.25 HVO_2721 amidophosphoribosyltransferase 25.15 1 8 8 32 2.143E9 16.76 20.49 7 15 1630.30 25.15 8 17 493 53.4 4.78 >sp|TRYP_PIG| 25.11 1 4 4 108 4.285E10 146.15 25.11 4 55 9159.09 25.11 4 53 231 24.4 7.18 HVO_2781 DNA-directed RNA polymerase subunit D 25.10 1 5 5 50 2.813E9 37.88 25.10 5 24 3476.76 25.10 5 26 259 28.1 4.32 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 25.06 1 7 7 28 1.343E9 21.12 25.06 7 14 1484.01 25.06 7 14 415 44.4 4.41 HVO_0034 acyl-CoA thioester hydrolase 25.00 1 3 3 17 2.084E8 8.53 25.00 3 9 907.40 25.00 3 8 164 18.3 4.65 HVO_2348 GTP cyclohydrolase MptA 25.00 1 5 5 25 6.871E8 24.08 23.05 4 12 1254.76 25.00 5 13 308 33.5 4.68 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 24.93 1 8 8 59 3.430E9 57.57 24.93 8 29 3419.26 24.93 8 30 357 40.3 4.40 HVO_1660 DisA-N domain protein 24.91 1 5 5 16 6.133E8 13.12 24.91 5 8 1003.02 24.91 5 8 269 28.9 4.73 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 24.71 1 7 7 19 1.278E8 12.56 21.51 6 9 1069.78 22.67 6 10 344 39.1 4.73 HVO_1649 methionine adenosyltransferase 24.63 1 6 6 18 4.296E8 11.96 24.63 6 9 774.62 24.63 6 9 402 43.5 4.45 HVO_1778 catalase-peroxidase 24.37 1 12 12 101 3.042E9 93.51 24.37 12 50 6549.44 24.37 12 51 718 80.0 4.31 HVO_1957 proteasome-activating nucleotidase 24.27 1 6 7 19 1.914E8 19.03 24.27 7 9 1039.86 24.27 7 10 412 45.6 4.48 HVO_1076 sugar nucleotidyltransferase 24.22 1 6 6 27 7.319E8 22.22 24.22 6 14 1458.14 22.36 5 13 322 35.8 4.20 HVO_1593 PAC2 family protein 24.19 1 3 3 12 3.126E8 7.10 24.19 3 6 370.72 24.19 3 6 248 26.6 4.46 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 24.19 1 6 6 16 8.667E8 13.16 15.93 4 7 915.55 21.24 5 9 339 38.1 4.50 HVO_2454 anthranilate synthase component I 24.05 1 9 9 37 7.505E8 25.73 20.80 8 18 1743.32 24.05 9 19 524 55.9 4.56 HVO_2436 malic enzyme (NADP) 23.97 1 13 15 54 9.368E8 53.89 21.84 12 24 3704.79 23.97 15 30 751 81.4 4.55 HVO_A0331 D-galactonate dehydratase 23.96 1 7 7 17 2.323E8 15.12 22.14 6 8 1009.95 23.96 7 9 384 42.8 4.83 HVO_2417 conserved hypothetical protein 23.59 1 3 3 17 3.343E8 13.89 23.59 3 8 961.34 23.59 3 9 195 21.6 3.65 HVO_A0266 IclR family transcription regulator 23.53 1 5 5 12 1.193E8 12.81 20.78 4 6 698.04 19.61 4 6 255 27.7 6.05 HVO_1527 glucose-1-phosphate uridylyltransferase 23.46 1 5 5 35 6.087E8 23.74 23.46 5 18 1732.70 23.46 5 17 243 27.5 4.70 HVO_A0636 YbaK domain protein 23.42 1 2 2 9 3.832E8 11.92 23.42 2 4 728.04 23.42 2 5 158 16.7 4.54 HVO_1847 oligoendopeptidase PepF 23.37 1 10 10 28 3.650E8 23.65 23.37 10 13 1406.01 23.37 10 15 599 68.5 4.41 HVO_1573 DNA gyrase subunit A 23.32 1 17 17 65 1.288E9 58.39 23.32 17 32 3862.71 23.32 17 33 862 94.8 4.56 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 23.08 1 4 4 14 4.787E8 8.12 23.08 4 6 625.61 23.08 4 8 377 39.2 4.18 HVO_0017 conserved hypothetical protein 22.92 1 4 4 11 4.490E8 6.23 22.92 4 6 653.48 19.27 3 5 192 21.9 4.50 HVO_0350 DNA-directed RNA polymerase subunit A'' 22.91 1 10 10 46 2.932E9 43.70 22.91 10 23 3052.22 22.91 10 23 419 46.1 4.35 HVO_2545 50S ribosomal protein L18 22.83 1 2 2 2 2.939E8 91.77 22.83 2 2 184 20.2 5.60 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 22.64 1 19 19 75 9.558E8 69.33 18.95 16 36 5482.32 21.72 18 39 1082 117.2 4.32 HVO_0214 L-lactate dehydrogenase 22.50 1 8 8 50 2.692E9 43.86 22.50 8 25 3147.47 22.50 8 25 320 34.5 4.49 HVO_0467 PhoU/TrkA-C domain protein 22.39 1 8 8 23 2.117E8 19.61 20.15 7 11 1193.36 22.39 8 12 402 43.3 4.49 HVO_1571 DNA topoisomerase VI subunit B 22.18 1 11 11 56 7.323E8 48.93 19.80 10 27 3123.09 22.18 11 29 798 87.4 4.73 HVO_1932 2-D-hydroxyacid dehydrogenase 22.08 1 6 6 12 1.715E8 3.96 14.29 4 5 417.79 22.08 6 7 308 33.0 4.60 HVO_0876 methylglyoxal synthase 22.05 1 2 2 2 8.398E7 78.60 22.05 2 2 127 13.9 4.48 HVO_1623 conserved hypothetical protein 21.81 1 5 5 21 3.411E8 17.80 21.81 5 11 918.28 21.81 5 10 298 32.8 4.56 HVO_1878 NAD synthase 21.74 1 4 4 10 2.894E8 0.00 12.68 3 4 463.43 21.74 4 6 276 29.6 4.37 HVO_2708 YfiH family protein 21.74 1 4 4 20 3.455E8 25.73 19.57 3 10 1414.00 21.74 4 10 322 35.4 4.35 HVO_1020 HEAT-PBS family protein 21.72 1 7 7 27 4.129E8 21.16 19.57 6 13 1788.28 20.29 6 14 419 45.5 3.95 HVO_2008 archaeosine synthase 21.71 1 8 8 19 3.073E8 7.95 18.63 7 9 669.45 21.71 8 10 585 64.9 4.81 HVO_2562 50S ribosomal protein L23 21.69 1 2 2 3 4.482E7 275.89 21.69 2 3 83 9.4 5.48 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 21.68 1 8 8 38 4.942E8 31.16 21.68 8 18 2144.62 21.68 8 20 512 53.8 4.78 HVO_2961 dihydrolipoyl dehydrogenase 21.68 1 6 6 24 5.395E8 18.21 21.68 6 12 1136.87 21.68 6 12 475 49.9 4.41 HVO_1871 UPF0447 family protein 21.56 1 9 9 33 1.116E9 19.75 18.16 8 15 1634.63 21.56 9 18 501 56.1 4.59 HVO_1575 arginase 21.40 1 2 2 8 5.623E8 3.02 21.40 2 4 172.40 21.40 2 4 299 31.0 4.58 HVO_0429 archaemetzincin 21.39 1 2 2 4 1.008E8 2.43 21.39 2 2 184.60 21.39 2 2 173 19.3 6.54 HVO_2700 AAA-type ATPase (CDC48 subfamily) 21.35 1 14 15 50 6.056E8 32.17 21.35 15 25 1960.86 21.35 15 25 754 82.8 4.75 HVO_1570 DNA topoisomerase VI subunit A 21.31 1 6 6 15 3.183E8 6.25 15.03 4 6 859.21 15.57 5 9 366 41.8 4.63 HVO_A0432 conserved hypothetical protein 21.23 1 0 6 27 4.306E8 20.36 21.23 6 14 1408.14 21.23 6 13 405 44.5 5.24 7428712 "keratin 1, type II, cytoskeletal - human" 21.15 1 0 15 94 1.716E9 78.82 21.15 15 46 5928.02 21.15 15 48 643 65.5 6.35 HVO_1134 conserved hypothetical protein 21.14 1 10 10 30 2.391E8 22.06 19.02 9 14 1414.32 21.14 10 16 757 80.6 4.35 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 21.09 1 2 2 7 7.262E7 7.22 21.09 2 4 433.29 21.09 2 3 128 13.0 4.31 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 21.03 1 8 8 52 1.035E9 40.60 21.03 8 26 2771.83 21.03 8 26 447 48.5 4.56 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 20.99 1 5 5 27 5.991E8 25.03 20.99 5 13 1763.85 20.99 5 14 362 39.6 4.82 HVO_A0307 Lrp/AsnC family transcription regulator 20.90 1 3 3 9 1.029E8 2.72 20.90 3 4 400.27 20.90 3 5 177 19.4 4.39 HVO_2951 tryptophan--tRNA ligase 20.79 1 7 7 11 1.947E8 0.00 17.39 6 7 200.38 6.99 3 4 529 59.1 4.53 HVO_1698 CBS/parB domain protein 20.75 1 3 4 12 8.678E8 0.00 15.85 3 6 358.60 20.75 4 6 265 29.4 4.92 HVO_1048 phosphoribosylformylglycinamidine synthase 2 20.66 1 9 9 63 1.094E9 88.67 19.66 8 31 5073.72 20.66 9 32 702 72.9 4.18 HVO_1025 acetyl-CoA C-acyltransferase 20.63 1 5 5 23 6.428E8 20.96 20.63 5 12 1443.81 20.63 5 11 383 40.7 4.56 HVO_1508 acetolactate synthase large subunit 20.61 1 7 7 38 9.637E8 44.61 20.61 7 19 2637.25 20.61 7 19 587 62.3 4.36 HVO_0795 transcription initiation factor TFB 20.60 1 6 6 15 3.451E8 8.00 20.60 6 7 847.31 20.60 6 8 335 37.4 5.59 HVO_2947 phenylalanine--tRNA ligase beta subunit 20.53 1 9 9 39 1.288E9 16.95 14.91 6 17 2259.97 20.53 9 22 570 63.3 4.46 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 20.47 1 4 4 9 4.984E8 4.55 20.47 4 5 177.88 20.47 4 4 386 42.1 4.49 HVO_0469 AstE family protein 20.44 1 5 5 14 1.921E8 6.43 20.44 5 7 480.61 20.44 5 7 318 33.9 5.85 HVO_0829 peptidase S9 family protein 20.39 1 7 7 30 4.460E8 17.93 18.26 6 13 1542.96 20.39 7 17 608 67.4 4.54 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 20.33 1 6 6 21 3.307E8 24.86 20.33 6 11 1427.19 17.31 5 10 364 39.3 4.35 HVO_0658 tRNA pseudouridine(13) synthase TruD 20.30 1 6 6 14 1.440E8 4.21 20.30 6 7 526.65 20.30 6 7 463 50.6 4.70 HVO_0100 NMD3 family protein 20.27 1 5 5 13 1.569E8 5.84 14.67 4 5 469.33 20.27 5 8 375 41.6 4.46 HVO_2205 arNOG06768 family NADH-binding domain protein 20.27 1 4 4 13 2.392E7 12.91 20.27 4 7 795.91 13.95 3 6 301 32.0 5.00 HVO_2614 uridine phosphorylase 19.83 1 4 4 26 1.500E9 27.51 19.83 4 13 1621.28 19.83 4 13 242 25.8 4.30 HVO_2945 valine--tRNA ligase 19.77 1 16 16 58 1.349E9 47.35 16.32 13 26 3310.93 19.77 16 32 870 98.9 4.36 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 19.74 1 8 8 29 3.199E8 21.83 18.46 7 14 1343.72 19.74 8 15 623 62.1 5.30 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 19.57 1 2 2 16 3.337E8 7.34 19.57 2 8 590.49 19.57 2 8 184 20.0 4.75 HVO_0466 citrate (si)-synthase 19.53 1 6 6 31 1.478E9 19.63 19.53 6 16 1441.25 16.62 5 15 379 41.8 4.55 HVO_0911 GTP-binding protein Drg 19.51 1 7 7 15 8.216E7 7.19 16.53 6 8 501.48 17.62 6 7 369 40.5 4.81 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 19.51 1 12 12 56 1.247E9 34.23 17.93 11 26 3297.86 19.51 12 30 697 74.5 4.13 HVO_0769 TRAM domain protein 19.40 1 2 2 4 0.000E0 3.87 19.40 2 2 151.45 19.40 2 2 134 14.8 4.32 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 19.37 1 4 4 18 7.395E8 14.02 19.37 4 9 947.64 19.37 4 9 253 26.0 4.60 HVO_0243 threonine aldolase 19.35 1 4 4 15 1.532E8 14.59 15.84 3 7 842.62 19.35 4 8 341 35.6 4.55 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 29 2.744E9 25.38 15.61 4 14 1877.74 19.31 5 15 378 39.7 4.67 HVO_A0496 UspA domain protein 19.31 1 5 5 13 3.977E8 7.65 19.31 5 7 471.60 15.86 4 6 290 31.4 4.60 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 19.30 1 6 6 26 1.231E8 18.59 19.30 6 13 1170.98 19.30 6 13 430 45.1 4.50 HVO_0056 conserved hypothetical protein 19.27 1 3 3 7 6.226E7 7.06 12.50 2 3 368.45 19.27 3 4 192 20.9 4.16 HVO_0976 5-(carboxyamino)imidazole ribonucleotide synthase 19.16 1 5 5 9 9.428E7 1.72 11.29 3 3 365.27 19.16 5 6 381 40.5 4.51 HVO_1289 OsmC domain protein 18.94 1 2 2 18 1.465E9 23.31 18.94 2 9 1206.01 18.94 2 9 132 14.2 3.85 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 18.86 1 7 7 25 5.697E8 19.65 18.86 7 13 1193.54 18.86 7 12 615 67.6 4.88 HVO_0697 PAC2 family protein 18.82 1 2 2 21 6.362E8 26.52 18.82 2 10 1250.92 18.82 2 11 255 27.4 4.08 HVO_0787 indole-3-glycerol-phosphate synthase 18.73 1 4 4 13 2.333E8 2.04 14.34 3 6 439.00 18.73 4 7 251 26.7 4.44 HVO_2688 TrmB family transcription regulator 18.70 1 6 6 37 1.110E9 32.55 18.70 6 19 2309.50 18.70 6 18 353 39.3 4.58 HVO_2763 homolog to ribonuclease Z 18.55 1 4 4 13 1.352E8 1.61 18.55 4 7 470.04 18.55 4 6 248 26.6 4.53 HVO_0122 phosphoglycerate dehydrogenase 18.52 1 4 4 11 1.022E8 6.71 18.52 4 6 465.42 12.96 3 5 324 35.3 5.35 HVO_2225 AstE family protein 18.48 1 3 3 10 7.560E8 4.62 18.48 3 5 278.58 18.48 3 5 341 36.9 4.53 HVO_0879 DUF371 family protein 18.44 1 2 2 2 1.743E7 0.00 18.44 2 2 141 15.3 4.65 HVO_0321 peptide chain release factor aRF-1 18.36 1 6 7 17 4.099E8 12.78 16.43 6 8 859.37 18.36 7 9 414 46.6 4.83 HVO_1235 creatininase 18.18 1 3 3 8 6.062E7 3.41 8.33 2 3 271.35 18.18 3 5 264 29.2 4.84 HVO_2313 siroheme decarboxylase AhbB 18.13 1 3 3 9 3.665E8 9.23 18.13 3 4 516.71 18.13 3 5 353 39.6 4.64 HVO_2068 "FtsZ family protein, type III" 18.11 1 4 4 14 2.122E8 14.05 18.11 4 7 988.82 18.11 4 7 370 38.7 4.49 HVO_0699 translation initiation factor aIF-2 alpha subunit 18.05 1 5 5 23 6.030E8 18.97 18.05 5 11 1427.41 18.05 5 12 266 29.5 4.46 HVO_2948 phenylalanine--tRNA ligase alpha subunit 18.04 1 5 5 41 8.572E8 25.24 18.04 5 20 1638.81 18.04 5 21 499 55.1 4.41 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 17.90 1 4 4 11 1.331E8 5.60 7.72 2 4 786.46 17.90 4 7 324 36.6 4.68 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 17.87 1 6 6 38 1.155E9 44.12 17.87 6 18 2491.26 17.87 6 20 347 36.8 4.93 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 17.86 1 4 4 21 1.088E9 21.11 17.86 4 10 1609.87 17.86 4 11 252 26.0 4.39 HVO_1965 rRNA maturation endonuclease Nob1 17.76 1 2 2 5 2.169E7 0.00 17.76 2 3 105.35 17.76 2 2 152 16.8 4.70 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 17.72 1 5 5 14 8.064E7 11.15 17.72 5 7 875.00 17.72 5 7 333 36.7 4.56 HVO_2168 AAA-type ATPase (MoxR subfamily) 17.63 1 4 4 9 1.712E8 0.00 12.46 3 4 277.60 17.63 4 5 329 35.9 4.54 HVO_0681 DNA topoisomerase I 17.50 1 10 10 32 1.126E8 15.17 14.40 8 14 1546.59 17.50 10 18 840 93.6 4.58 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 17.48 1 5 5 18 2.238E8 13.99 17.48 5 9 887.65 17.48 5 9 349 37.0 4.70 HVO_0661 dCTP deaminase (dUMP-forming) 17.44 1 2 2 2 7.255E7 1.79 17.44 2 2 195 21.2 4.59 HVO_1979 tRNA pseudouridine synthase Pus10 17.33 1 6 6 15 5.058E8 8.25 15.69 5 6 676.35 17.33 6 9 427 46.9 4.39 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 17.33 1 4 4 10 2.734E8 11.65 8.20 2 4 594.19 17.33 4 6 427 45.4 4.56 HVO_2156 UspA domain protein 17.28 1 5 5 13 7.403E8 3.81 14.29 4 7 466.48 17.28 5 6 301 31.6 4.69 HVO_2793 conserved hypothetical protein 17.06 1 2 2 4 8.672E7 2.15 17.06 2 2 149.19 17.06 2 2 252 27.1 4.46 HVO_1164 HD family hydrolase 17.04 1 4 4 16 4.318E8 3.88 17.04 4 8 545.11 17.04 4 8 270 29.8 4.87 HVO_2706 translation initiation factor aIF-2B delta subunit 17.02 1 3 3 12 5.034E8 7.12 17.02 3 6 575.80 17.02 3 6 282 30.7 4.42 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 16.86 1 5 5 14 6.278E7 11.22 8.33 3 6 664.90 16.86 5 8 516 56.7 4.89 HVO_0997 peptidase M24 family protein 16.85 1 3 3 9 3.002E7 2.71 16.85 3 4 316.53 16.85 3 5 368 39.9 4.49 HVO_0452 leucine--tRNA ligase 16.70 1 10 10 25 7.143E8 19.38 10.23 7 11 1531.05 16.70 10 14 958 109.5 4.37 HVO_0054 glycine--tRNA ligase 16.67 1 7 7 31 3.104E9 21.77 14.31 6 13 2399.91 16.67 7 18 594 64.9 4.21 HVO_2256 DUF262 family protein 16.67 1 8 8 29 4.827E8 24.81 15.15 7 14 2012.66 16.67 8 15 462 54.9 4.89 HVO_2707 GFO family oxidoreductase 16.67 1 5 5 13 3.905E8 12.44 16.67 5 7 695.12 15.05 4 6 372 41.0 4.55 HVO_2879 ornithine cyclodeaminase 16.57 1 4 4 4 3.070E8 243.02 16.57 4 4 332 34.6 4.45 HVO_1073 ThiJ/PfpI family protein 16.52 1 3 3 10 1.052E8 8.81 16.52 3 5 560.74 16.52 3 5 224 23.9 4.12 HVO_3014 origin-associated GTP-binding protein OapA 16.43 1 3 3 3 1.196E8 124.42 16.43 3 3 213 24.0 5.01 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 16.40 1 3 3 10 1.872E8 4.02 9.52 2 4 522.73 16.40 3 6 189 21.7 4.46 HVO_2072 S-layer glycoprotein 16.32 1 6 6 53 1.945E9 30.61 12.82 5 27 2051.36 16.32 6 26 827 85.1 3.65 HVO_1453 glutamate dehydrogenase (NADP) 16.31 1 5 5 16 2.881E8 10.65 16.31 5 8 867.87 16.31 5 8 417 45.7 4.49 HVO_1550 acyl-CoA thioester hydrolase 16.25 1 2 2 10 5.244E7 5.74 16.25 2 5 471.11 16.25 2 5 160 17.6 4.55 HVO_1853 UspA domain protein 16.22 1 2 2 4 8.150E7 2.23 16.22 2 2 172.42 16.22 2 2 148 16.0 4.58 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 16.11 1 4 4 27 6.147E8 19.66 13.06 3 13 1555.70 16.11 4 14 360 38.5 4.45 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 16.02 1 3 3 12 1.255E8 11.28 16.02 3 6 666.87 16.02 3 6 231 25.0 4.25 HVO_1079 sulfate adenylyltransferase small subunit 16.00 1 4 4 8 4.820E7 3.46 16.00 4 4 329.89 16.00 4 4 325 37.5 4.18 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 15.93 1 4 4 12 1.442E8 8.62 15.93 4 6 532.98 15.93 4 6 383 42.0 4.49 HVO_2383 DNA repair and recombination protein RadB 15.72 1 3 3 6 4.960E7 4.62 15.72 3 3 277.04 15.72 3 3 229 24.6 5.02 HVO_1291 fumarylacetoacetase family protein 15.64 1 3 3 8 6.026E8 6.99 15.64 3 4 360.49 15.64 3 4 243 26.3 4.55 HVO_0044 acetylglutamate kinase 15.60 1 4 4 15 5.085E8 12.75 15.60 4 7 880.02 15.60 4 8 327 33.2 4.49 HVO_2227 siroheme decarboxylase AhbA 15.56 1 3 3 9 7.261E7 1.71 15.56 3 4 256.99 15.56 3 5 347 39.1 4.69 HVO_0812 phosphoenolpyruvate synthase 15.51 1 9 9 25 2.179E8 20.92 14.32 8 12 1173.25 11.83 8 13 761 83.1 4.63 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 15.36 1 2 3 8 2.782E8 4.21 15.36 3 4 486.25 15.36 3 4 267 29.1 4.63 HVO_0158 TATA-binding transcription initiation factor 15.34 1 2 3 11 6.804E8 7.84 15.34 3 6 451.39 15.34 3 5 189 20.3 4.22 HVO_2153 probable copper-containing oxidoreductase 15.32 1 5 5 14 1.674E8 15.15 15.32 5 7 808.07 15.32 5 7 385 42.1 5.82 HVO_2333 conserved hypothetical protein 15.26 1 5 5 12 1.714E8 8.21 15.26 5 6 468.61 15.26 5 6 308 34.9 4.54 HVO_A0087 fumarylacetoacetase family protein 15.22 1 3 3 11 6.751E8 13.35 15.22 3 5 668.86 15.22 3 6 289 32.0 4.21 HVO_2380 AAA-type ATPase (CDC48 subfamily) 15.21 1 10 10 26 4.545E8 11.66 15.21 10 13 881.41 14.00 9 13 743 81.9 4.82 HVO_C0001 Orc1-type DNA replication protein 15.20 1 7 7 20 1.051E8 11.45 15.20 7 10 889.09 15.20 7 10 408 45.2 4.97 HVO_1783 conserved hypothetical protein 15.18 1 2 2 8 4.928E7 3.38 15.18 2 4 312.97 15.18 2 4 224 24.1 5.90 HVO_2777 30S ribosomal protein S9 15.15 1 2 2 8 9.306E7 3.82 15.15 2 4 337.20 15.15 2 4 132 14.7 9.74 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 15.13 1 6 6 17 2.104E8 18.01 13.24 5 8 870.96 15.13 6 9 423 43.9 4.31 HVO_B0055 conserved hypothetical protein 15.11 1 4 4 8 4.464E8 2.01 15.11 4 4 339.02 15.11 4 4 225 23.9 4.69 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 15.09 1 3 3 10 1.611E8 3.41 15.09 3 5 395.73 15.09 3 5 265 28.7 4.87 HVO_1087 UspA domain protein 14.89 1 2 2 8 2.940E7 7.07 14.89 2 4 470.42 14.89 2 4 141 15.2 4.98 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 14.80 1 15 15 50 5.808E8 28.69 14.80 15 25 1955.65 13.86 14 25 1284 141.2 4.35 HVO_0042 acetylornithine deacetylase 14.70 1 4 4 11 1.119E9 7.08 12.34 3 5 610.04 14.70 4 6 381 41.0 4.34 HVO_1496 phosphotransferase system component I 14.69 1 7 7 27 2.034E8 12.62 13.27 6 13 1227.89 14.69 7 14 565 60.3 4.21 HVO_1327 AAA-type ATPase (CDC48 subfamily) 14.67 1 5 6 16 2.647E8 11.92 12.64 5 7 871.30 14.67 6 9 736 78.1 4.88 HVO_1967 glucose-6-phosphate isomerase 14.65 1 4 4 12 3.826E8 10.34 14.65 4 6 751.35 14.65 4 6 430 45.6 4.40 HVO_0123 signal recognition particle 54K protein 14.62 1 4 4 11 2.861E8 7.36 6.24 2 4 464.04 14.62 4 7 465 50.9 4.50 HVO_0228 ParA domain protein 14.57 1 3 3 6 2.167E8 4.14 6.88 2 3 407.60 11.74 2 3 247 24.6 4.16 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 14.52 1 4 4 12 2.181E8 6.60 14.52 4 6 488.62 14.52 4 6 365 39.0 4.61 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 14.48 1 5 5 18 1.003E9 15.20 14.48 5 9 916.78 14.48 5 9 373 40.2 4.44 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 14.43 1 2 2 5 1.305E8 0.00 14.43 2 2 213.05 14.43 2 3 97 10.8 4.53 HVO_A0458 ParA domain protein 14.43 1 2 2 6 2.597E8 2.36 14.43 2 3 252.68 14.43 2 3 291 32.2 4.79 HVO_1093 probable S-adenosylmethionine-dependent methyltransferase 14.42 1 2 2 4 2.810E7 3.90 14.42 2 2 217.89 14.42 2 2 208 22.6 4.36 HVO_2373 30S ribosomal protein S8e 14.40 1 2 2 9 1.594E8 7.96 14.40 2 4 297.19 14.40 2 5 125 13.6 10.48 HVO_1823 UspA domain protein 14.38 1 2 2 10 2.326E8 7.09 14.38 2 5 578.36 14.38 2 5 153 16.4 4.60 HVO_1809 isochorismatase family protein 14.21 1 2 2 4 8.408E7 0.00 14.21 2 2 97.13 14.21 2 2 190 21.0 4.55 HVO_0916 diphthine synthase 14.13 1 2 2 8 3.249E8 6.64 14.13 2 4 276.70 14.13 2 4 269 29.1 4.54 HVO_1348 probable YjeF family carbohydrate kinase 14.02 1 4 4 10 1.059E8 9.15 14.02 4 5 365.30 14.02 4 5 478 48.8 4.45 HVO_1372 pyrroline-5-carboxylate reductase 14.01 1 3 3 7 3.964E8 6.30 8.17 2 3 478.15 14.01 3 4 257 26.8 4.01 HVO_1670 rRNA/tRNA 2'-O-methyltransferase complex protein Nop5 13.93 1 2 2 5 4.221E7 0.00 13.93 2 2 105.18 13.93 2 3 280 30.0 4.92 HVO_2988 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase 13.87 1 2 2 4 2.376E7 3.97 13.87 2 2 186.24 13.87 2 2 238 24.7 4.15 HVO_1578 probable NADH dehydrogenase 13.85 1 3 3 11 2.127E8 7.09 13.85 3 6 536.76 13.85 3 5 397 42.8 4.40 HVO_2600 methionyl aminopeptidase 13.85 1 4 4 12 1.891E8 8.14 9.80 3 5 642.74 13.85 4 7 296 32.3 4.41 HVO_0234 conserved hypothetical protein 13.82 1 2 2 6 3.560E7 4.65 13.82 2 3 236.17 13.82 2 3 275 28.1 4.48 HVO_2717 alanine--tRNA ligase 13.82 1 5 5 18 2.025E8 14.07 8.54 3 7 1074.73 13.82 5 11 398 41.6 4.39 HVO_B0324 conserved hypothetical protein 13.81 1 4 4 11 1.023E8 5.62 8.24 3 5 430.63 13.81 4 6 449 48.0 4.58 47132620 keratin 2a [Homo sapiens] 13.77 1 5 9 43 1.008E9 39.37 13.77 9 20 2746.40 13.77 9 23 639 65.4 8.00 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 10 3.635E8 4.96 13.66 2 5 548.73 13.66 2 5 183 20.0 4.21 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 13.53 1 5 5 14 1.709E8 10.47 13.53 5 7 589.49 13.53 5 7 584 63.3 4.79 HVO_B0371 aldehyde dehydrogenase 13.51 1 4 4 10 1.103E8 7.95 13.51 4 6 356.73 13.51 4 4 496 52.5 4.39 HVO_2536 CHP00300 family protein 13.46 1 3 3 5 3.924E8 0.00 6.73 2 2 99.58 13.46 3 3 416 44.8 4.51 HVO_1547 isoleucine--tRNA ligase 13.42 1 9 9 55 7.989E8 57.15 13.42 9 28 3411.92 13.42 9 27 1043 117.9 4.30 HVO_1804 nicotinate phosphoribosyltransferase 13.40 1 5 5 19 2.200E8 4.02 10.31 4 9 663.84 13.40 5 10 388 41.1 4.60 HVO_1373 acyl-CoA dehydrogenase 13.32 1 3 3 11 7.825E7 5.46 13.32 3 5 585.11 13.32 3 6 383 42.5 4.61 HVO_A0388 Lrp/AsnC family transcription regulator 13.22 1 2 2 6 2.801E8 2.16 13.22 2 3 138.25 13.22 2 3 174 20.1 4.86 HVO_B0253 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 13.11 1 2 3 8 1.617E8 3.91 13.11 3 4 409.73 13.11 3 4 267 28.8 4.55 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 13.00 1 3 3 12 2.298E8 3.85 13.00 3 6 472.58 13.00 3 6 277 30.6 4.30 HVO_B0200 malate synthase 12.84 1 3 3 11 5.743E8 7.37 12.84 3 6 516.96 12.84 3 5 436 48.3 4.30 HVO_1824 conserved hypothetical protein 12.82 1 4 4 12 2.589E8 15.06 12.82 4 6 989.94 12.82 4 6 429 47.4 4.20 HVO_A0485 aminotransferase class V 12.82 1 3 3 8 2.023E8 4.56 12.82 3 4 312.44 12.82 3 4 351 37.3 4.26 HVO_B0066 Lrp/AsnC family transcription regulator 12.80 1 2 2 4 5.910E7 1.96 12.80 2 2 151.27 12.80 2 2 164 18.5 4.41 HVO_1531 UDP-glucose 6-dehydrogenase 12.79 1 4 4 8 2.401E8 5.95 12.79 4 4 368.38 12.79 4 4 430 45.9 4.50 HVO_0400 conserved hypothetical protein 12.70 1 2 2 3 1.270E8 3.45 12.70 2 3 126 13.9 4.68 HVO_2960 dihydrolipoamide S-acyltransferase 12.67 1 5 5 20 5.771E7 15.73 12.67 5 10 939.13 12.67 5 10 521 54.9 4.40 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 12.65 1 3 3 14 5.017E8 12.44 12.65 3 7 872.69 12.65 3 7 324 33.6 3.99 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 12.61 1 3 3 19 3.597E8 6.91 8.96 2 9 989.28 12.61 3 10 357 39.8 4.41 HVO_0818 threonine synthase 12.60 1 4 4 23 3.417E8 11.38 12.60 4 11 1166.61 12.60 4 12 389 40.8 4.31 HVO_1169 "probable glycosyltransferase, type 1" 12.50 1 2 2 3 8.172E7 102.78 12.50 2 3 368 40.8 4.73 HVO_1407 HTH domain protein 12.44 1 2 2 5 5.841E7 2.56 12.44 2 2 281.38 12.44 2 3 225 24.9 4.45 HVO_1867 lysine--tRNA ligase 12.43 1 6 6 20 4.266E8 6.20 8.83 4 9 660.29 12.43 6 11 555 62.1 4.46 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 12.41 1 3 3 8 7.880E7 7.22 12.41 3 4 440.79 12.41 3 4 266 29.7 4.32 HVO_B0115 fumarylacetoacetase family protein 12.37 1 3 3 12 3.595E8 5.05 12.37 3 6 587.46 12.37 3 6 283 30.3 4.21 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 12.27 1 2 2 6 3.744E8 4.45 12.27 2 3 318.49 12.27 2 3 269 28.3 4.49 HVO_0087 porphobilinogen synthase 12.23 1 4 4 11 1.415E8 7.99 9.48 3 5 609.98 12.23 4 6 327 35.3 4.72 HVO_1553 hydroxypyruvate reductase 12.22 1 4 4 8 4.900E7 4.42 12.22 4 4 317.71 12.22 4 4 442 45.2 4.50 HVO_1337 rpa-associated protein 12.20 1 6 6 27 7.230E8 18.42 12.20 6 13 1356.88 12.20 6 14 623 64.8 3.68 HVO_1097 diaminopimelate epimerase 12.15 1 3 3 10 1.664E8 9.05 12.15 3 5 603.87 12.15 3 5 288 29.9 4.48 HVO_1500 1-phosphofructokinase 12.13 1 2 2 6 2.914E7 1.90 12.13 2 3 228.30 12.13 2 3 305 32.0 4.51 HVO_1629 conserved hypothetical protein 12.05 1 4 4 6 1.407E8 4.53 5.08 2 2 295.39 12.05 4 4 531 56.3 4.69 HVO_C0069 GFO family oxidoreductase 12.04 1 3 3 13 1.421E8 1.99 12.04 3 6 445.70 12.04 3 7 324 36.0 5.10 HVO_1174 transcription initiation factor TFE 11.93 1 2 2 4 1.185E8 371.14 11.93 2 4 176 20.6 4.23 HVO_2412 Lrp/AsnC family transcription regulator 11.80 1 2 2 3 6.365E7 169.98 11.80 2 3 161 17.7 4.55 HVO_2610 deoxyribose-phosphate aldolase 11.79 1 2 2 3 1.791E8 146.59 11.79 2 3 212 21.9 4.23 HVO_B0287 TRAM domain protein 11.63 1 2 2 4 5.401E7 1.96 11.63 2 2 151.37 11.63 2 2 172 18.0 4.31 HVO_2636 PspA domain protein 11.59 1 2 2 2 3.037E6 27.45 11.59 2 2 276 30.9 4.61 HVO_0569 RIO-type serine/threonine protein kinase 11.55 1 2 2 5 1.433E8 0.00 11.55 2 3 70.08 11.55 2 2 303 34.4 4.94 HVO_2001 tRNA-guanine(15) transglycosylase 11.43 1 3 3 13 1.382E8 13.55 11.43 3 7 612.13 11.43 3 6 516 56.3 4.59 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 11.42 1 3 3 10 2.328E8 8.12 11.42 3 5 512.14 11.42 3 5 464 53.1 4.54 HVO_2883 conserved hypothetical protein 11.40 1 6 6 14 1.544E8 2.89 11.40 6 7 513.34 11.40 6 7 702 78.9 4.48 HVO_1344 SBDS family protein 11.34 1 2 2 6 5.844E7 3.49 11.34 2 3 190.79 11.34 2 3 238 26.5 4.51 HVO_2759 peptidase M42 family protein 11.30 1 4 4 12 4.906E8 9.25 11.30 4 6 428.08 11.30 4 6 354 37.0 4.40 HVO_1129 conserved hypothetical protein 11.28 1 3 3 15 2.043E8 17.17 11.28 3 8 914.21 10.00 2 7 390 43.0 4.44 HVO_2481 HD family hydrolase 11.28 1 2 2 5 7.876E7 0.00 11.28 2 3 136.21 11.28 2 2 390 42.7 6.14 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 11.25 1 5 5 14 9.901E7 6.16 11.25 5 7 486.95 11.25 5 7 658 72.1 4.70 HVO_2663 probable oxidoreductase (aldo-keto reductase family protein) 11.22 1 2 2 4 1.094E8 3.25 11.22 2 2 239.88 11.22 2 2 294 32.5 4.75 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 11.15 1 2 2 6 3.060E7 6.46 11.15 2 3 324.49 11.15 2 3 305 34.1 4.91 HVO_2918 thymidylate synthase 11.14 1 2 2 5 1.175E8 5.64 11.14 2 2 229.46 11.14 2 3 332 37.5 4.61 HVO_0326 CTP-dependent riboflavin kinase 10.97 1 3 3 8 1.413E8 1.88 10.97 3 4 282.69 10.97 3 4 237 25.9 4.55 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 10.94 1 2 2 6 1.649E8 5.95 10.94 2 3 303.69 10.94 2 3 265 29.3 4.92 HVO_1503 3-isopropylmalate dehydratase small subunit 10.89 1 2 2 11 3.828E8 6.46 10.89 2 6 348.43 10.89 2 5 202 22.0 4.15 HVO_1491 HAD superfamily hydrolase 10.78 1 4 4 17 7.401E7 10.30 10.78 4 9 1010.70 8.09 3 8 408 44.4 4.60 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 10.76 1 4 4 10 1.483E8 1.87 10.76 4 5 350.29 10.76 4 5 353 36.7 4.65 HVO_0894 acyl-CoA synthetase 10.73 1 3 5 11 2.639E8 6.72 10.73 5 6 365.56 9.06 4 5 662 74.3 4.48 HVO_0561 50S ribosomal protein L15e 10.71 1 2 2 5 8.269E7 1.61 10.71 2 3 220.01 10.71 2 2 196 22.5 11.15 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 10.58 1 4 4 10 1.111E8 4.39 10.58 4 5 460.55 10.58 4 5 378 39.8 4.45 HVO_1356 sensor box histidine kinase 10.55 1 3 3 12 2.114E8 3.70 10.55 3 6 522.16 10.55 3 6 550 61.1 4.60 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 10.43 1 3 3 5 1.408E8 0.00 10.43 3 3 130.43 8.41 2 2 345 36.9 4.68 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 10.42 1 0 5 23 1.456E8 11.69 10.42 5 11 1150.14 10.42 5 12 384 42.4 5.40 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 10.42 1 3 3 10 4.716E7 3.95 10.42 3 5 287.94 10.42 3 5 403 41.1 4.73 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 10.37 1 4 4 12 6.573E8 9.55 10.37 4 6 547.70 10.37 4 6 299 32.0 4.53 HVO_2952 tRNA-splicing endonuclease 10.32 1 2 2 7 3.848E7 2.85 10.32 2 4 164.22 10.32 2 3 339 37.4 4.74 HVO_0406 RNA-binding protein AU-1 10.26 1 4 4 12 1.369E8 12.22 10.26 4 6 492.99 10.26 4 6 468 49.9 4.53 HVO_0853 DNA double-strand break repair protein Mre11 10.20 1 3 3 10 8.354E7 11.13 10.20 3 5 491.74 10.20 3 5 441 48.1 4.39 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 10.20 1 5 5 14 2.291E8 9.64 10.20 5 7 628.20 10.20 5 7 706 73.3 4.39 HVO_0552 DNA mismatch repair protein MutS 10.17 1 7 7 18 3.788E8 11.12 8.12 6 9 910.18 10.17 7 9 924 99.2 4.65 HVO_2427 replication factor C large subunit 10.04 1 4 4 14 1.813E8 9.91 10.04 4 7 477.19 10.04 4 7 488 53.4 4.67 HVO_0868 NAD-dependent epimerase/dehydratase 10.03 1 3 3 7 1.072E8 2.18 10.03 3 3 329.44 10.03 3 4 329 36.1 4.55 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 10 5.514E8 3.84 10.00 2 5 458.17 10.00 2 5 190 21.0 4.74 HVO_A0228 5'-nucleotidase SurE 9.97 1 2 2 4 4.900E5 0.00 9.97 2 2 122.25 9.97 2 2 291 31.5 4.59 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 9.92 1 2 2 14 1.285E9 6.76 9.92 2 7 881.59 9.92 2 7 363 39.7 4.25 HVO_0733 transcription initiation factor TFB 9.82 1 1 3 14 6.542E8 12.67 9.82 3 7 1035.80 9.82 3 7 326 37.2 6.00 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 9.78 1 4 4 11 1.528E8 7.09 8.36 3 5 512.70 9.78 4 6 634 66.1 4.54 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 9.76 1 3 3 7 2.118E8 0.00 9.76 3 4 179.31 5.48 2 3 420 45.0 4.86 HVO_1347 probable cyclic pyranopterin monophosphate synthase accessory protein 9.71 1 2 2 4 1.026E9 0.00 9.71 2 2 112.75 9.71 2 2 175 18.8 4.63 HVO_1323 "shikimate kinase, archaeal-type" 9.69 1 2 2 11 5.030E8 13.14 9.69 2 5 906.49 9.69 2 6 289 29.5 4.30 HVO_0970 ribulose-bisphosphate carboxylase large subunit 9.66 1 4 4 13 1.632E8 4.35 6.04 3 6 588.77 9.66 4 7 414 43.9 4.59 HVO_1283 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase / threonine 3-dehydrogenase) 9.64 1 2 2 2 4.014E9 0.00 9.64 2 2 332 35.8 4.61 HVO_A0064 Orc1-type DNA replication protein 9.62 1 2 2 2 3.311E7 81.54 9.62 2 2 499 55.5 4.91 HVO_2581 quinolinate synthase A 9.61 1 3 3 16 2.856E8 2.27 9.61 3 8 673.06 9.61 3 8 385 42.0 4.41 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 9.48 1 2 2 2 1.359E8 76.71 9.48 2 2 327 36.0 4.73 HVO_2229 flavin-containing amine-oxidoreductase 9.30 1 2 2 4 8.547E7 2.08 9.30 2 2 121.61 9.30 2 2 344 37.9 4.92 HVO_1594 tRNA/rRNA cytosine-C5-methylase 9.27 1 2 2 6 1.385E8 4.75 9.27 2 3 360.92 9.27 2 3 313 34.6 4.69 HVO_2712 3'-5' RNA ligase 9.26 1 4 4 11 1.756E8 12.08 9.26 4 5 622.29 9.26 4 6 486 53.4 4.92 HVO_A0133 conserved hypothetical protein 9.25 1 2 2 8 1.959E8 6.06 9.25 2 4 438.16 9.25 2 4 292 30.8 5.17 HVO_2639 DUF1611 family protein 9.09 1 3 3 14 3.511E7 12.74 9.09 3 7 898.97 9.09 3 7 341 36.3 4.44 HVO_1895 KEOPS complex subunit Kae1/Bud32 9.06 1 3 3 14 1.492E8 12.51 9.06 3 7 754.83 9.06 3 7 552 59.0 5.07 HVO_0979 NADH dehydrogenase-like complex subunit B 9.01 1 2 2 6 3.207E8 4.55 9.01 2 3 298.67 9.01 2 3 233 26.1 5.01 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 8.96 1 2 2 6 2.313E7 4.14 8.96 2 3 297.41 8.96 2 3 268 27.9 4.87 HVO_1139 squalene synthase 8.94 1 2 2 4 7.297E7 517.13 8.94 2 4 358 39.7 4.54 HVO_2350 YyaL family protein 8.88 1 3 3 9 1.023E8 6.44 6.52 2 4 446.48 8.88 3 5 552 58.8 4.59 21961227 Keratin 6B [Homo sapiens] 8.87 1 0 6 35 1.456E8 15.20 8.87 6 17 1438.36 8.87 6 18 564 60.0 8.00 HVO_0656 conserved hypothetical protein 8.71 1 2 2 4 9.436E6 1.77 8.71 2 2 183.71 8.71 2 2 241 26.3 6.11 HVO_0197 PurE family protein 8.70 1 2 2 4 3.370E7 1.88 8.70 2 2 120.22 8.70 2 2 253 25.5 4.42 HVO_0867 HD family hydrolase 8.70 1 2 2 8 5.166E7 3.63 8.70 2 4 298.47 8.70 2 4 230 26.2 4.78 HVO_1716 7-cyano-7-deazaguanine synthase 8.61 1 2 2 2 7.711E7 140.04 8.61 2 2 244 26.8 4.42 HVO_2880 probable peptide chain release factor pelota 8.43 1 2 2 3 3.117E8 2.30 8.43 2 3 356 39.3 4.63 HVO_0755 NAD-dependent epimerase/dehydratase 8.39 1 2 2 2 1.656E7 1.80 8.39 2 2 298 32.3 4.91 HVO_2425 GNAT family acetyltransferase 8.33 1 2 2 7 9.430E7 3.74 8.33 2 3 166.69 8.33 2 4 216 24.4 4.54 HVO_2160 conserved hypothetical protein 8.20 1 12 12 80 9.960E8 72.69 8.20 12 40 4897.33 8.20 12 40 2257 232.7 3.92 HVO_1309 peptidase M24 family protein 8.18 1 3 3 10 1.622E7 9.81 8.18 3 5 599.69 8.18 3 5 391 42.1 4.36 HVO_0968 NADH dehydrogenase-like complex subunit CD 8.16 1 0 4 14 8.225E8 10.41 8.16 4 7 731.12 8.16 4 7 564 63.3 4.60 HVO_2648 phosphoglycerate dehydrogenase 8.15 1 2 2 7 2.098E8 0.00 8.15 2 3 235.00 8.15 2 4 319 34.2 4.64 HVO_1354 DNA mismatch repair protein MutS 8.10 1 3 3 7 9.296E7 3.75 8.10 3 4 289.18 5.34 2 3 580 62.1 4.56 HVO_0322 MinD/ParA domain protein 8.09 1 2 2 3 3.157E8 2.26 8.09 2 3 581 58.8 3.70 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 8.06 1 3 3 9 1.105E8 5.33 8.06 3 5 350.00 5.88 2 4 459 50.5 4.63 HVO_2321 bacterial-type DNA primase DnaG 8.05 1 3 3 10 7.508E7 5.62 8.05 3 5 422.21 8.05 3 5 472 49.4 4.36 HVO_1914 acetyl-CoA C-acyltransferase 7.96 1 2 2 2 4.082E7 191.88 7.96 2 2 377 39.9 4.41 HVO_2467 NADPH:quinone reductase 7.48 1 2 2 8 8.285E7 4.10 7.48 2 4 390.90 7.48 2 4 321 33.0 4.51 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 7.47 1 2 2 8 9.056E7 9.62 7.47 2 4 524.24 7.47 2 4 442 46.9 4.58 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 7.46 1 0 4 10 2.266E8 4.52 5.48 3 4 491.43 7.46 4 6 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 7.46 1 0 4 10 2.266E8 4.52 5.48 3 4 491.43 7.46 4 6 456 49.2 4.77 HVO_0195 ribose-5-phosphate isomerase 7.39 1 2 2 6 2.066E8 4.07 7.39 2 3 247.87 7.39 2 3 230 23.2 4.54 HVO_1375 O-succinylbenzoic acid--CoA ligase 7.33 1 3 3 8 9.357E7 4.13 7.33 3 4 237.58 7.33 3 4 614 64.7 4.28 HVO_2662 homolog to lactoylglutathione lyase 7.29 1 2 2 2 4.397E7 2.23 7.29 2 2 329 36.5 4.48 HVO_2421 probable DNA-binding protein 7.23 1 2 2 8 7.942E7 1.77 7.23 2 4 380.46 7.23 2 4 235 25.8 4.89 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 7.21 1 3 3 24 4.047E8 15.35 7.21 3 11 1333.76 7.21 3 13 430 44.2 4.37 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 7.21 1 2 2 4 4.651E7 375.24 7.21 2 4 305 32.7 4.56 HVO_1711 glucoamylase 7.15 1 7 7 16 1.414E8 11.63 7.15 7 8 759.18 5.56 6 8 1511 166.1 4.64 HVO_1685 conserved hypothetical protein 7.11 1 3 3 10 9.473E7 3.92 7.11 3 5 414.98 7.11 3 5 492 54.5 5.74 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 7.09 1 0 5 23 1.456E8 11.69 7.09 5 11 1150.14 7.09 5 12 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 7.09 1 0 5 23 1.456E8 11.69 7.09 5 11 1150.14 7.09 5 12 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 7.09 1 0 5 23 1.456E8 11.69 7.09 5 11 1150.14 7.09 5 12 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 7.09 1 0 5 23 1.456E8 11.69 7.09 5 11 1150.14 7.09 5 12 564 60.0 7.72 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 7.09 1 2 2 9 8.239E7 8.69 7.09 2 4 510.08 7.09 2 5 395 42.4 4.54 HVO_2761 mevalonate kinase 7.08 1 2 2 6 8.341E7 3.46 7.08 2 3 260.43 7.08 2 3 367 38.2 4.31 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 7.07 1 2 2 8 2.068E8 9.25 7.07 2 4 611.67 7.07 2 4 297 32.3 3.98 HVO_A0439 DUF2800 family protein 7.06 1 2 2 4 4.472E7 0.00 7.06 2 2 94.72 7.06 2 2 326 36.9 4.51 HVO_0541 aconitate hydratase 7.04 1 4 4 16 1.230E8 13.62 7.04 4 8 709.67 7.04 4 8 938 102.1 4.40 HVO_1625 conserved hypothetical protein 7.03 1 3 3 10 1.287E8 7.86 7.03 3 5 639.57 7.03 3 5 654 70.1 4.04 HVO_0551 DNA mismatch repair protein MutL 6.94 1 4 4 11 1.168E8 8.02 4.76 3 5 470.27 6.94 4 6 735 78.7 4.50 HVO_0724 ArsA family ATPase 6.85 1 2 2 8 2.010E7 4.00 6.85 2 4 254.28 6.85 2 4 409 43.9 4.22 HVO_B0256 aldehyde ferredoxin oxidoreductase 6.85 1 2 3 7 4.616E8 2.23 6.85 3 4 158.83 3.60 2 3 555 59.9 4.55 HVO_B0114 IclR family transcription regulator 6.75 1 2 2 2 1.208E6 0.00 6.75 2 2 252 28.4 5.44 HVO_1758 oxidoreductase (homolog to thioredoxin-disulfide reductase) 6.69 1 2 2 10 9.170E7 5.30 6.69 2 5 605.88 6.69 2 5 329 36.3 4.49 HVO_B0057 precorrin-3B C17-methyltransferase 6.69 1 2 2 10 3.808E8 12.87 6.69 2 5 804.44 6.69 2 5 344 36.3 4.31 HVO_0194 Orc1-type DNA replication protein 6.68 1 2 2 6 2.029E8 0.00 6.68 2 3 296.33 6.68 2 3 374 42.2 4.94 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 6.67 1 2 2 3 5.347E7 0.00 6.67 2 3 345 37.0 3.95 HVO_0854 DNA double-strand break repair ATPase Rad50 6.61 1 4 4 7 5.615E7 0.00 5.60 3 3 272.15 6.61 4 4 893 100.0 4.58 HVO_2908 dihydropteroate synthase 6.60 1 2 2 8 6.524E7 3.66 6.60 2 4 226.45 6.60 2 4 379 40.8 4.53 HVO_1098 diaminopimelate decarboxylase 6.51 1 2 2 6 3.296E8 6.94 6.51 2 3 315.91 6.51 2 3 415 44.4 5.02 4504911 keratin 13 isoform b [Homo sapiens] 6.43 1 0 3 8 9.938E6 4.52 4.29 2 3 444.21 6.43 3 5 420 45.8 4.88 HVO_0662 HTH domain protein / thiamine-phosphate synthase 6.35 1 2 2 7 3.836E7 1.92 6.35 2 4 330.59 6.35 2 3 299 31.9 4.44 HVO_B0001 Orc1-type DNA replication protein 6.34 1 2 2 6 8.600E7 3.08 6.34 2 3 270.94 6.34 2 3 410 45.8 5.33 HVO_A0586 sugar nucleotidyltransferase 6.33 1 2 2 3 5.691E7 239.49 6.33 2 3 411 43.7 4.69 HVO_0014 ATP-dependent DNA helicase Hel308a 6.29 1 4 4 14 1.104E8 8.55 6.29 4 7 626.89 6.29 4 7 827 90.3 4.67 4557890 keratin 5 [Homo sapiens] 6.27 1 0 5 23 1.192E8 11.69 6.27 5 11 1086.59 6.27 5 12 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 6.27 1 0 5 23 1.192E8 11.69 6.27 5 11 1086.59 6.27 5 12 590 62.4 8.06 HVO_2746 "ribosome biogenesis protein KsgA, 16S rRNA-methylating" 6.27 1 2 2 6 7.381E7 4.52 6.27 2 3 191.64 6.27 2 3 287 31.8 4.93 HVO_B0143 receiver/sensor box histidine kinase 6.20 1 3 3 10 7.306E7 9.58 6.20 3 5 559.38 6.20 3 5 597 66.0 4.41 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 6.19 1 2 2 6 9.095E7 0.00 6.19 2 3 204.79 6.19 2 3 388 41.9 4.35 HVO_0591 L-threonine-O-3-phosphate decarboxylase 6.18 1 2 2 2 1.020E8 97.71 6.18 2 2 340 36.0 4.54 HVO_2266 hypothetical protein 6.09 1 2 2 6 7.212E7 2.96 6.09 2 3 335.31 6.09 2 3 493 56.7 4.54 HVO_A0328 2-keto-3-deoxygluconate kinase 5.97 1 1 2 6 2.434E7 1.70 5.97 2 3 221.10 5.97 2 3 318 34.0 4.60 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 5.90 1 0 3 8 9.938E6 4.52 3.93 2 3 444.21 5.90 3 5 458 49.6 4.96 HVO_1723 DNA repair helicase Rad25 5.90 1 3 3 5 3.245E7 4.12 3.88 2 2 288.77 5.90 3 3 695 76.8 4.69 HVO_2812 AstE family protein 5.87 1 2 2 4 9.597E7 2.16 5.87 2 2 211.37 5.87 2 2 341 37.3 5.14 HVO_2187 CHP01210 family protein 5.83 1 2 2 4 1.277E8 0.00 5.83 2 2 126.51 5.83 2 2 360 40.0 4.58 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 5.73 1 3 3 5 1.240E8 0.00 4.30 2 2 114.99 5.73 3 3 838 89.1 4.65 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 5.72 1 0 3 15 3.669E8 8.27 5.72 3 7 831.23 5.72 3 8 472 51.6 5.16 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 5.71 1 0 3 15 3.669E8 8.27 5.71 3 7 831.23 5.71 3 8 473 51.2 5.05 HVO_1465 naphthoate synthase 5.57 1 2 2 2 1.195E8 171.95 5.57 2 2 305 33.9 4.83 HVO_1710 alpha amylase 5.47 1 4 4 13 9.003E7 6.21 5.47 4 6 509.86 5.47 4 7 677 75.0 4.45 HVO_2158 malic enzyme (NADP) 5.46 1 0 2 11 8.109E8 14.56 5.46 2 5 747.72 5.46 2 6 751 81.4 4.55 HVO_0639 AAA-type ATPase (MoxR subfamily) 5.38 1 2 2 3 5.094E7 323.68 5.38 2 3 316 34.7 4.89 HVO_1816 dihydroorotase 5.36 1 2 2 9 8.037E7 4.54 5.36 2 4 363.10 5.36 2 5 429 45.4 4.40 386849 keratin type II 5.33 1 0 3 7 3.982E7 2.48 5.33 3 4 287.99 5.33 3 3 563 59.9 7.94 HVO_0580 putative tRNA 2-thiolation protein 5.30 1 2 2 4 2.493E7 3.62 5.30 2 2 118.37 5.30 2 2 321 36.1 5.01 HVO_3000 DNA ligase (NAD) 5.29 1 3 3 9 7.603E8 8.44 5.29 3 4 581.35 5.29 3 5 699 75.8 4.50 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 5.24 1 2 2 5 4.456E7 7.57 5.24 2 3 203.72 5.24 2 2 573 62.9 4.45 HVO_0670 glutathione S-transferase 5.21 1 2 2 2 1.762E7 0.00 5.21 2 2 326 38.1 4.56 1668744 HHa5 hair keratin type I intermediate filament [Homo sapiens] 5.18 1 0 2 2 6.512E8 82.91 5.18 2 2 425 47.5 4.81 3724107 type I hair keratin 5 [Homo sapiens] 5.18 1 0 2 2 6.512E8 82.91 5.18 2 2 425 47.6 4.81 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 5.17 1 5 5 10 6.935E7 6.77 5.17 5 5 409.89 5.17 5 5 1335 150.5 4.60 HVO_1113 "FtsZ family protein, type III" 5.14 1 0 2 10 6.815E8 6.80 5.14 2 5 459.08 5.14 2 5 389 40.8 4.89 HVO_C0043 conserved hypothetical protein 5.14 1 2 2 2 4.621E7 131.13 5.14 2 2 661 73.8 4.75 HVO_B0233 alpha-L-arabinofuranosidase 5.09 1 2 2 6 9.326E7 1.80 5.09 2 3 198.90 5.09 2 3 511 57.5 4.39 HVO_1656 YyaL family protein 4.98 1 3 3 9 1.084E8 3.71 4.98 3 4 333.90 4.98 3 5 703 77.3 4.49 31559823 keratin 25D [Homo sapiens] 4.96 1 0 3 17 3.586E8 7.66 4.96 3 8 803.61 4.96 3 9 464 50.6 5.47 HVO_A0257 Orc1-type DNA replication protein 4.94 1 2 2 4 2.368E7 2.09 4.94 2 2 157.84 4.94 2 2 425 48.0 4.94 HVO_A0158 acyl-CoA synthetase 4.92 1 1 2 2 3.223E7 77.55 4.92 2 2 650 71.2 4.63 HVO_1160 type IV pilus biogenesis complex ATPase subunit 4.91 1 2 2 4 0.000E0 0.00 4.91 2 2 37.72 4.91 2 2 1100 120.4 4.37 HVO_2888 homolog to elongator complex protein ELP3 4.91 1 3 3 8 2.238E7 3.72 4.91 3 4 340.70 4.00 2 4 550 62.6 5.01 94538345 type I hair keratin 5 [Homo sapiens] 4.84 1 0 2 2 6.512E8 82.91 4.84 2 2 455 50.3 4.91 HVO_1340 "probable glycosyltransferase, type 1" 4.80 1 2 2 4 6.069E7 0.00 4.80 2 2 161.43 4.80 2 2 375 41.0 4.42 HVO_C0057 Orc1-type DNA replication protein 4.78 1 1 2 2 6.987E7 0.00 4.78 2 2 418 46.3 5.02 HVO_B0038A D-xylonate dehydratase 4.61 1 0 2 7 4.193E8 2.59 4.61 2 4 302.73 4.61 2 3 412 45.5 4.55 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 4.56 1 2 2 7 9.812E7 4.38 4.56 2 3 393.12 4.56 2 4 482 50.6 4.31 HVO_0689 chromosome segregation protein Smc 4.44 1 4 4 6 4.346E7 3.43 2.66 3 3 199.56 3.06 3 3 1240 138.1 4.39 HVO_2004 serine O-acetyltransferase 4.18 1 1 2 8 6.331E8 0.00 4.18 2 3 354.09 4.18 2 5 287 31.9 5.21 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 4.17 1 0 2 4 3.387E8 2.57 4.17 2 2 230.62 4.17 2 2 432 48.1 5.02 HVO_0634 Orc1-type DNA replication protein 4.17 1 1 2 2 7.328E7 0.00 4.17 2 2 408 45.6 4.65 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 4.08 1 2 2 10 2.193E8 12.65 4.08 2 5 751.36 4.08 2 5 612 67.3 4.16 HVO_0069 sulfatase 4.08 1 2 2 2 3.844E7 136.13 4.08 2 2 515 57.4 4.35 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 4.05 1 1 2 8 1.240E9 0.00 4.05 2 5 192.11 4.05 2 3 444 47.1 4.77 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 4.00 1 0 2 3 3.268E8 152.26 4.00 2 3 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 4.00 1 0 2 3 3.268E8 152.26 4.00 2 3 400 44.1 5.14 HVO_1565 DNA ligase (ATP) 3.93 1 2 2 9 6.003E7 4.29 3.93 2 3 544.50 3.93 2 6 585 62.7 4.44 HVO_0029 UvrABC system protein B 3.87 1 2 2 4 1.376E7 0.00 3.87 2 4 698 79.0 4.45 HVO_C0042 helicase domain protein 3.77 1 3 3 6 1.204E8 6.50 3.77 3 3 325.56 3.77 3 3 1274 144.4 4.67 31559819 keratin 25C [Homo sapiens] 3.49 1 0 2 15 2.123E8 7.66 3.49 2 7 756.38 3.49 2 8 459 49.8 5.14 31074631 keratin 1b [Homo sapiens] 3.46 1 0 2 21 7.954E8 17.24 3.46 2 9 1539.90 3.46 2 12 578 61.8 5.97 HVO_A0156 acyl-CoA synthetase 3.46 1 0 2 6 1.011E8 4.19 3.46 2 3 251.48 3.46 2 3 664 74.0 4.40 HVO_B0149 oleate hydratase 3.38 1 1 2 4 2.533E8 0.00 3.38 2 2 130.39 3.38 2 2 533 60.1 4.64 4504919 keratin 8 [Homo sapiens] 3.31 1 0 3 19 1.192E8 9.20 3.31 3 9 925.72 3.31 3 10 483 53.7 5.59 HVO_1228 halocyanin 3.29 1 2 2 4 1.822E7 3.73 3.29 2 2 107.26 3.29 2 2 821 83.7 4.17 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 3.27 1 2 2 4 4.164E7 0.00 3.27 2 2 139.29 3.27 2 2 398 43.4 4.37 HVO_1683 4-alpha-glucanotransferase 3.23 1 2 2 4 6.655E7 0.00 3.23 2 2 127.55 3.23 2 2 496 56.3 4.45 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 3.11 1 2 2 6 3.492E7 5.99 3.11 2 3 291.80 3.11 2 3 740 85.6 4.70 HVO_0220 ATP-dependent DNA helicase MCM 2.85 1 2 2 6 5.816E7 4.08 2.85 2 3 232.81 2.85 2 3 702 78.8 4.73 HVO_B0154 receiver/sensor box histidine kinase 1.61 1 2 2 4 3.736E7 355.61 1.61 2 4 1301 144.1 4.39