Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_0359 translation elongation factor aEF-1 alpha subunit 79.57 1 20 24 1120 8.017E10 1053.84 75.06 22 517 82543.76 79.57 24 603 421 45.7 4.73 HVO_0356 translation elongation factor aEF-2 76.34 1 44 44 863 2.560E10 728.63 75.65 43 433 48599.01 75.52 43 430 727 80.4 4.73 HVO_0880 conserved hypothetical protein 71.99 1 25 25 216 2.943E9 208.73 71.99 25 108 14345.11 71.99 25 108 307 36.3 4.74 HVO_1921 serine--tRNA ligase 65.65 1 24 24 97 1.883E9 72.27 64.57 23 51 5716.10 49.35 21 46 460 52.0 4.46 HVO_2862 serine hydroxymethyltransferase 65.06 1 15 15 183 6.977E9 143.23 62.89 14 94 10939.76 65.06 15 89 415 44.3 4.53 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 64.74 1 13 13 203 6.694E9 169.13 64.74 13 104 11078.00 64.74 13 99 312 34.5 4.98 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 64.57 1 15 15 284 1.333E10 224.49 64.57 15 144 17306.91 64.57 15 140 350 37.6 4.54 HVO_1273 inosine-5'-monophosphate dehydrogenase 60.44 1 17 18 155 3.247E9 134.34 52.41 16 75 9069.88 57.43 17 80 498 53.3 4.55 HVO_0025 thiosulfate sulfurtransferase 59.79 1 11 11 249 1.475E10 188.78 57.34 9 124 12894.93 59.79 11 125 286 32.1 4.28 HVO_2783 30S ribosomal protein S4 59.43 1 11 11 83 5.314E9 57.94 59.43 11 41 4921.06 59.43 10 42 175 20.1 5.24 HVO_0175 DNA polymerase sliding clamp 58.70 1 8 8 110 5.041E9 77.59 44.53 7 52 5564.59 58.70 8 58 247 26.7 4.39 HVO_2588 isocitrate dehydrogenase (NADP) 58.47 1 19 19 175 9.318E9 174.06 55.37 17 87 11726.90 51.07 17 88 419 45.8 4.59 HVO_0677 aspartate--tRNA ligase 58.29 1 19 19 213 8.539E9 164.12 55.99 17 105 11889.08 58.29 19 108 434 48.7 4.50 HVO_2544 30S ribosomal protein S5 57.48 1 11 12 91 1.065E10 54.13 57.48 12 47 4612.01 55.14 11 44 214 23.3 9.29 HVO_2900 fumarate hydratase 56.50 1 16 16 140 6.372E9 124.17 56.50 16 69 8490.54 48.83 15 71 469 50.1 4.78 HVO_2724 beta-lactamase domain protein 56.22 1 17 17 168 5.346E9 145.30 56.22 17 85 8870.17 56.22 17 83 450 50.1 5.40 HVO_2968 phosphoglycerate dehydrogenase 56.00 1 21 21 200 7.869E9 166.39 56.00 21 101 12260.06 56.00 21 99 525 55.3 4.36 HVO_0433 F420H2:NADP oxidoreductase 54.50 1 7 7 28 1.145E9 25.42 54.50 7 14 1596.15 54.50 7 14 222 23.3 4.72 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 53.91 1 15 15 122 6.036E9 132.81 52.08 14 59 9422.63 53.91 15 63 384 41.4 4.41 HVO_0203 replication factor C small subunit 52.60 1 11 11 42 6.942E8 18.55 52.60 11 21 1570.20 41.28 10 21 327 36.2 4.51 HVO_0581 "cell division protein FtsZ, type II" 52.50 1 13 13 81 2.709E9 78.08 52.50 13 40 5237.99 52.50 13 41 400 42.5 4.75 HVO_1145 30S ribosomal protein S1e 52.27 1 12 12 66 2.625E9 74.93 52.27 12 33 4770.93 49.55 11 33 220 24.8 4.86 HVO_0859 FeS assembly ATPase SufC 52.16 1 14 14 98 3.426E9 72.72 50.17 13 45 5813.66 52.16 14 53 301 33.4 4.35 HVO_0348 DNA-directed RNA polymerase subunit B' 51.89 1 24 24 169 2.378E9 140.66 48.28 23 84 9207.95 46.31 23 85 609 67.7 4.92 HVO_0239 glutamine synthetase 51.54 1 16 17 111 7.484E9 81.02 51.54 17 56 6530.41 51.54 17 55 456 50.5 4.56 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 51.44 1 14 14 162 1.006E10 119.62 48.82 13 77 9059.07 51.44 14 85 381 41.0 4.23 HVO_0869 glutamate synthase large subunit 51.29 1 55 56 391 4.912E9 332.07 50.30 55 195 24349.54 51.29 56 196 1511 163.8 4.70 HVO_1502 3-isopropylmalate dehydrogenase 50.93 1 13 13 72 3.496E9 67.18 43.21 12 33 5336.07 50.93 13 39 324 33.7 4.23 HVO_1132 adenylosuccinate synthase 50.56 1 20 20 236 7.430E9 159.36 47.40 19 116 12038.92 50.11 19 120 443 48.2 4.56 HVO_2029 Lrp/AsnC family transcription regulator 50.33 1 4 5 23 1.327E9 3.78 26.80 3 10 952.51 50.33 5 13 153 16.9 4.21 HVO_2552 30S ribosomal protein S4e 50.20 1 9 9 141 1.825E10 121.39 50.20 9 67 7550.65 50.20 9 74 247 26.6 4.58 HVO_0778 thermosome subunit 3 50.19 1 17 19 112 1.763E9 109.49 44.27 17 54 7601.53 50.19 19 58 524 55.2 4.59 HVO_2861 conserved hypothetical protein 50.18 1 9 9 44 9.140E8 44.57 50.18 8 22 2512.29 41.45 8 22 275 29.1 4.27 HVO_0347 DNA-directed RNA polymerase subunit B'' 50.10 1 23 23 165 2.227E9 113.86 48.75 22 81 7985.55 50.10 23 84 521 58.9 5.00 HVO_0314 A-type ATP synthase subunit C 50.00 1 15 15 81 1.351E9 60.99 45.98 14 39 4595.36 47.99 14 42 348 38.7 4.50 HVO_0861 SufB domain protein 50.00 1 13 13 99 4.110E9 99.85 50.00 13 50 7234.06 42.54 12 49 402 44.7 4.23 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 49.47 1 7 7 29 1.213E9 17.50 49.47 7 15 1546.29 49.47 7 14 188 20.5 4.60 HVO_2558 30S ribosomal protein S3 49.34 1 14 14 193 5.831E9 210.28 45.07 13 95 13989.71 45.39 12 98 304 33.4 4.06 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 49.29 1 20 20 339 1.608E10 355.33 43.42 18 165 23812.41 49.29 20 174 631 68.4 4.49 HVO_0133 thermosome subunit 1 48.57 1 19 21 126 3.072E9 100.62 48.21 20 62 7625.73 46.07 19 64 560 58.9 4.25 HVO_1082 homolog to orotate phosphoribosyltransferase 48.57 1 8 8 36 1.444E9 27.91 43.33 7 17 1899.14 48.57 8 19 210 22.3 4.42 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 48.43 1 10 10 74 3.435E9 50.72 46.69 9 36 3865.21 48.43 10 38 287 31.0 4.73 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 48.40 1 10 10 62 1.884E9 50.49 48.40 10 30 3243.58 48.40 10 32 281 30.6 4.59 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 48.31 1 17 17 120 4.570E9 100.23 41.89 16 58 7282.14 47.13 16 62 592 66.6 4.61 HVO_0329 branched-chain amino acid aminotransferase 48.08 1 14 14 100 3.575E9 98.45 47.76 13 50 6265.25 48.08 14 50 312 35.0 4.58 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 47.94 1 5 5 40 1.198E9 11.61 37.11 4 16 2271.90 47.94 5 24 194 20.7 4.12 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 47.89 1 6 6 31 2.063E9 17.32 36.84 5 16 1604.31 47.89 6 15 190 20.6 4.30 HVO_0974 "6,7-dimethyl-8-ribityllumazine synthase" 47.76 1 4 4 12 9.872E7 5.28 41.04 3 4 1019.07 47.76 4 8 134 13.9 4.55 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 47.21 1 13 13 70 3.146E9 49.00 40.98 11 30 4684.27 47.21 13 40 305 33.8 4.74 HVO_0055 CBS domain protein 47.18 1 9 9 65 2.035E9 57.72 47.18 9 33 4044.44 47.18 9 32 284 30.8 4.27 HVO_A0207 CRISPR-associated protein Cas7 46.47 1 9 9 41 8.441E8 29.45 37.65 8 21 2413.32 46.47 9 20 340 38.2 4.54 HVO_2413 translation elongation factor aEF-1 alpha subunit 46.43 1 12 16 127 1.231E10 65.16 46.43 15 60 6446.06 46.19 15 67 420 45.6 4.75 HVO_0317 A-type ATP synthase subunit B 46.37 1 13 14 122 7.371E9 107.74 44.66 13 59 8639.38 44.87 13 63 468 51.9 4.25 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 46.37 1 8 8 113 3.185E9 102.54 43.25 7 55 7007.45 46.37 8 58 289 29.8 4.27 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 46.24 1 10 10 52 1.175E9 38.68 46.24 10 27 3167.70 46.24 10 25 266 27.8 4.84 40354192 keratin 10 [Homo sapiens] 46.23 1 0 28 156 2.177E9 107.13 45.21 27 77 8779.80 46.23 28 79 584 58.8 5.16 HVO_1955 aconitate hydratase 45.72 1 24 24 303 8.863E9 288.89 45.72 24 152 20488.97 45.72 24 151 654 70.4 4.45 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 45.53 1 0 28 156 2.177E9 107.13 44.52 27 77 8779.80 45.53 28 79 593 59.5 5.21 HVO_2015 conserved hypothetical protein 45.51 1 10 10 178 1.659E10 168.78 45.51 10 87 11383.75 38.26 9 91 345 37.7 4.25 HVO_1300 triosephosphate isomerase 45.33 1 6 6 36 4.106E9 32.70 24.30 5 17 2745.77 45.33 6 19 214 21.3 4.26 HVO_1541 glycerol kinase 45.29 1 18 18 117 5.526E9 91.93 41.96 16 55 7591.23 45.29 18 62 510 56.7 4.50 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 45.17 1 11 11 41 1.017E9 24.98 45.17 11 20 1927.00 45.17 11 21 445 47.8 4.86 HVO_2204 "FtsZ family protein, type III" 45.06 1 13 16 78 3.194E9 73.03 43.54 15 38 4848.53 45.06 15 40 395 42.0 4.68 HVO_2384 CBS domain protein 45.00 1 17 17 101 4.236E9 61.71 45.00 17 52 5423.80 42.11 15 49 380 42.5 5.01 HVO_2549 30S ribosomal protein S8 44.62 1 5 5 32 8.073E8 21.78 44.62 5 16 1421.55 44.62 5 16 130 14.1 4.79 HVO_0789 tryptophan synthase alpha subunit 43.68 1 8 8 24 4.175E8 14.93 41.52 7 12 1387.03 43.68 8 12 277 29.6 4.21 HVO_2419 hydroxymethylglutaryl-CoA synthase 43.60 1 14 14 58 1.945E9 34.35 43.60 14 29 2758.64 43.60 14 29 445 50.1 4.64 HVO_0455 thermosome subunit 2 43.45 1 19 20 138 3.224E9 96.48 42.01 19 64 7487.50 43.45 20 74 557 59.3 4.37 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 43.17 1 19 19 206 4.401E9 184.42 41.98 18 102 12594.94 43.17 19 104 586 64.0 4.49 HVO_2889 RecJ domain protein 43.07 1 23 23 203 7.946E9 164.20 41.56 22 100 12181.31 41.84 22 103 729 79.1 4.37 HVO_2913 superoxide dismutase (Mn) 42.71 1 0 4 30 5.746E9 37.43 42.71 4 15 2415.00 42.71 4 15 199 22.3 4.48 HVO_0316 A-type ATP synthase subunit A 42.66 1 19 19 153 6.415E9 147.59 42.66 19 77 9129.33 42.66 19 76 586 64.5 4.25 HVO_0480 phosphoglycerate kinase 42.64 1 14 14 77 2.537E9 66.05 42.64 14 38 5072.39 42.64 14 39 401 43.6 4.37 HVO_A0475 superoxide dismutase (Mn) 42.50 1 0 4 30 5.746E9 37.43 42.50 4 15 2415.00 42.50 4 15 200 22.4 4.45 HVO_2519 conserved hypothetical protein 42.15 1 11 11 49 1.169E9 34.20 26.70 8 20 3281.72 40.58 10 29 382 40.7 4.35 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 42.10 1 14 14 98 2.583E9 86.95 40.19 13 46 5972.20 42.10 14 52 525 56.4 4.40 HVO_2242 homolog to translation initiation factor aIF-2 beta subunit / probable RNA-binding protein 42.08 1 7 7 27 3.860E8 18.08 42.08 7 14 1160.31 42.08 7 13 202 22.2 5.11 HVO_1091 proteasome alpha subunit 42.06 1 10 11 53 2.277E9 53.78 42.06 11 27 3647.72 38.49 10 26 252 27.6 4.56 HVO_1080 conserved hypothetical protein 42.02 1 5 5 27 4.702E8 14.58 42.02 5 13 893.13 38.30 4 14 188 21.1 4.31 HVO_2621 phosphoenolpyruvate carboxylase 41.58 1 31 32 177 3.949E9 117.32 40.02 30 87 9205.45 41.58 31 90 897 102.3 4.64 HVO_0860 SufB domain protein 41.39 1 14 14 129 4.643E9 98.14 38.24 13 62 7648.70 41.39 14 67 476 53.2 4.69 HVO_A0205 CRISPR-associated endoribonuclease Cas6 41.18 1 10 10 51 3.901E8 41.83 41.18 10 26 2713.79 41.18 10 25 272 31.0 5.44 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 41.13 1 9 9 52 1.971E9 43.25 41.13 9 25 2647.36 41.13 9 27 355 38.2 4.68 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 41.13 1 16 16 61 1.476E9 38.65 38.10 14 27 2986.50 41.13 16 34 496 55.0 4.53 HVO_0024 thiosulfate sulfurtransferase 41.09 1 7 7 24 8.869E8 8.19 36.43 6 10 1321.33 41.09 7 14 258 28.4 4.30 HVO_0850 proteasome-activating nucleotidase 40.99 1 14 14 61 1.453E9 27.64 39.26 13 29 2789.29 38.77 13 32 405 45.6 4.60 HVO_2191 formyltetrahydrofolate deformylase 40.98 1 10 10 54 2.619E9 48.16 40.98 10 26 3405.00 40.98 10 28 327 36.2 4.63 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 40.91 1 9 9 34 9.820E8 25.34 40.91 9 17 1724.39 40.91 9 17 286 31.2 4.54 HVO_0046 putative glutamate--argW ligase 40.89 1 9 9 50 9.682E8 48.41 40.89 9 25 3114.50 40.89 9 25 291 31.9 4.87 HVO_2548 50S ribosomal protein L6 40.45 1 4 4 21 2.844E8 22.31 40.45 4 11 1238.97 40.45 4 10 178 19.6 4.68 HVO_2487 aspartate-semialdehyde dehydrogenase 40.41 1 7 7 64 3.662E9 38.17 40.41 7 32 2931.39 40.41 7 32 344 36.6 4.41 HVO_2740 nucleoside-diphosphate kinase 40.26 1 5 5 66 1.732E9 57.02 40.26 5 35 4685.50 40.26 5 31 154 17.5 4.50 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 40.18 1 8 8 44 5.416E8 28.90 40.18 8 20 2725.00 40.18 8 24 336 36.8 4.12 HVO_0999 DRTGG domain protein 39.95 1 10 10 53 1.169E9 34.44 39.95 10 27 2408.95 39.95 10 26 378 39.8 4.44 HVO_0104 DNA repair and recombination protein RadA 39.94 1 11 11 78 3.165E9 54.22 34.69 10 36 5721.14 39.94 11 42 343 37.3 4.64 HVO_0980 NADH dehydrogenase-like complex subunit CD 39.68 1 12 16 56 1.178E9 42.51 33.21 14 28 2674.44 39.68 16 28 557 63.4 4.53 HVO_1545 dihydroxyacetone kinase subunit DhaL 39.66 1 7 7 59 2.211E9 43.79 39.66 7 30 3348.35 39.66 7 29 232 24.8 4.48 HVO_2646 dihydroxy-acid dehydratase 39.55 1 14 14 100 2.287E9 67.75 39.55 14 50 5196.37 39.55 14 50 584 61.8 4.42 HVO_1504 3-isopropylmalate dehydratase large subunit 39.53 1 16 17 130 4.127E9 104.84 38.48 16 66 7935.30 39.53 17 64 473 51.6 4.55 HVO_0240 Lrp/AsnC family transcription regulator 39.47 1 4 5 27 1.222E9 8.55 34.21 4 13 1265.62 39.47 5 14 152 16.9 4.39 HVO_0353 30S ribosomal protein S12 39.44 1 8 8 49 1.521E9 38.03 39.44 8 26 2395.54 35.92 7 23 142 15.5 9.91 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 39.44 1 9 9 55 1.747E9 48.54 39.44 9 28 2986.70 39.44 9 27 360 39.6 4.39 HVO_2013 "FtsZ family protein, type III" 39.34 1 7 7 32 3.801E8 45.02 39.34 7 16 2625.50 36.80 6 16 394 41.5 4.61 HVO_1198 UspA domain protein 39.31 1 5 5 22 1.201E9 23.12 39.31 5 11 1467.97 39.31 5 11 145 15.6 4.75 HVO_B0118 SMC-like protein Sph2 38.98 1 20 20 89 1.839E9 57.98 36.34 18 45 3925.48 33.23 18 44 644 73.8 4.41 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 38.78 1 10 10 39 1.162E9 31.62 38.78 10 20 2197.81 38.78 10 19 343 38.4 4.94 HVO_A0206 CRISPR-associated protein Cas8b 38.77 1 21 21 75 1.373E9 49.36 37.52 20 37 3466.44 34.59 19 38 717 79.3 4.60 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 38.68 1 19 20 78 1.419E9 59.69 38.68 19 37 4215.97 38.68 20 41 623 62.1 5.30 HVO_2040 NAD-dependent epimerase/dehydratase 38.56 1 5 10 54 1.477E9 41.40 38.56 10 27 2938.50 32.35 8 27 306 33.8 4.51 HVO_3007 malate dehydrogenase 38.49 1 11 11 198 8.392E9 204.23 38.49 11 100 11275.15 36.51 10 98 304 32.6 4.40 HVO_1858 30S ribosomal protein S19e 38.41 1 3 3 10 4.601E7 0.00 26.49 2 5 234.76 38.41 3 5 151 16.7 4.84 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 38.22 1 7 7 45 1.578E9 31.49 38.22 7 21 2623.10 38.22 7 24 259 28.0 4.50 HVO_1506 ketol-acid reductoisomerase 38.22 1 7 7 38 6.495E8 43.26 38.22 7 19 2594.23 38.22 7 19 348 37.9 4.34 HVO_2774 enolase 38.10 1 10 10 58 3.955E9 47.93 38.10 10 29 3553.62 38.10 10 29 399 42.0 4.37 HVO_0536 ferritin 38.07 1 3 3 9 3.431E8 8.67 24.43 2 4 415.54 38.07 3 5 176 19.9 4.50 HVO_1507 acetolactate synthase small subunit 38.07 1 6 6 22 3.348E8 12.29 38.07 6 11 1011.89 38.07 6 11 218 23.7 4.94 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 38.05 1 9 9 55 1.529E9 55.69 35.50 8 26 4009.23 38.05 9 29 431 46.1 4.48 HVO_2756 50S ribosomal protein L10 37.93 1 7 7 52 1.788E9 40.21 37.93 7 26 2693.28 37.93 7 26 348 36.9 3.99 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 37.82 1 16 16 76 1.690E9 54.92 33.49 15 38 4123.12 37.02 15 38 624 67.6 4.27 HVO_0161 ATP phosphoribosyltransferase 37.72 1 8 8 37 8.153E8 30.22 33.81 7 17 2374.96 37.72 8 20 281 30.4 4.60 HVO_1973 conserved hypothetical protein 37.72 1 3 3 16 1.512E8 17.56 37.72 3 8 1368.11 37.72 3 8 167 18.1 4.36 HVO_2555 30S ribosomal protein S17 37.72 1 2 2 4 2.692E7 0.00 37.72 2 2 58.86 37.72 2 2 114 12.7 4.81 HVO_0449 prephenate dehydratase 37.69 1 7 7 33 5.178E8 30.13 34.33 6 15 1881.05 37.69 7 18 268 28.7 4.64 HVO_0350 DNA-directed RNA polymerase subunit A'' 37.47 1 11 12 59 2.810E9 47.43 35.56 11 29 3497.04 37.47 12 30 419 46.1 4.35 HVO_1212 KaiC-type circadian regulator CirA 37.40 1 8 8 47 1.578E9 50.61 35.37 7 23 3930.15 37.40 8 24 246 27.5 4.45 HVO_2969 threonine synthase 37.23 1 13 13 76 3.269E9 53.79 36.99 12 37 3941.93 37.23 13 39 419 44.4 4.49 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 37.14 1 9 9 39 2.674E9 20.63 37.14 9 19 2094.73 37.14 8 20 280 30.1 4.44 HVO_1454 aspartate carbamoyltransferase catalytic subunit 36.51 1 7 7 23 3.357E8 9.81 36.51 7 13 879.44 23.68 5 10 304 33.7 4.92 HVO_2813 RimK family protein 36.20 1 13 13 85 2.278E9 70.25 36.20 13 42 4752.70 36.20 13 43 453 49.0 4.73 HVO_2773 30S ribosomal protein S2 36.15 1 5 5 55 6.298E9 66.15 36.15 5 28 4508.69 30.00 4 27 260 28.3 4.16 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 35.89 1 10 10 46 1.176E9 19.71 33.70 9 22 2092.06 35.89 10 24 457 48.4 4.35 HVO_0138 tyrosine--tRNA ligase 35.67 1 9 9 37 9.873E8 15.85 27.13 8 18 1449.66 33.54 8 19 328 36.1 4.34 HVO_0212 homolog to lactoylglutathione lyase 35.48 1 2 2 9 2.852E8 5.32 35.48 2 6 331.90 35.48 2 3 124 13.5 4.13 HVO_2336 pyridoxal biosynthesis lyase PdxS 35.43 1 7 7 34 3.772E8 20.24 31.79 6 15 1884.99 35.43 7 19 302 32.5 4.81 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 35.30 1 15 15 40 5.438E8 25.94 30.35 13 19 2074.67 35.30 15 21 626 67.6 4.65 HVO_0358 homoserine dehydrogenase 35.02 1 5 6 20 8.378E8 15.59 35.02 6 10 1011.81 35.02 6 10 317 32.4 4.44 HVO_1481 UspA domain protein 34.97 1 4 4 39 2.535E9 35.25 34.97 4 20 2487.80 34.97 4 19 163 17.7 4.40 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 34.83 1 16 16 73 8.019E8 47.52 28.83 14 36 4131.96 33.33 15 37 600 65.3 4.68 HVO_1590 DnaK-type molecular chaperone Hsp70 34.72 1 19 19 137 3.113E9 128.68 34.72 19 69 8339.68 32.32 18 68 625 67.2 4.18 HVO_0806 pyruvate kinase 34.70 1 14 14 83 2.829E9 85.51 34.70 14 41 5319.41 34.70 14 42 585 62.0 4.54 HVO_1637 FKBP-type peptidylprolyl isomerase 34.64 1 7 8 73 4.922E9 54.39 26.14 7 36 3982.95 33.01 7 37 306 33.8 3.76 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 34.60 1 11 11 42 1.250E9 27.64 25.11 8 19 1799.60 34.60 11 23 474 53.4 4.59 HVO_1684 threonine--tRNA ligase 34.53 1 19 19 131 2.840E9 86.75 34.53 19 65 6867.38 34.53 19 66 643 73.4 4.45 HVO_0729 inorganic pyrophosphatase 34.46 1 7 7 50 2.144E9 44.88 34.46 7 26 2922.95 34.46 7 24 177 20.4 4.16 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 34.44 1 9 9 36 2.395E8 23.42 34.44 9 17 1720.33 34.44 9 19 363 39.3 4.97 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 34.36 1 11 11 55 1.484E9 23.60 30.50 9 25 2810.74 34.36 11 30 259 29.9 4.36 17318569 keratin 1 [Homo sapiens] 34.32 1 1 22 190 5.502E9 177.49 34.32 22 95 12654.50 34.32 22 95 644 66.0 8.12 HVO_0049 argininosuccinate synthase 34.32 1 12 12 59 3.364E9 38.06 34.32 12 29 3042.59 34.32 12 30 405 44.5 4.34 HVO_0324 arginine--tRNA ligase 33.56 1 17 17 82 1.546E9 68.56 28.11 14 38 4533.75 33.56 17 44 587 65.0 4.35 HVO_0313 A-type ATP synthase subunit E 33.51 1 4 4 22 5.032E8 16.59 26.29 3 10 1059.14 33.51 4 12 194 22.0 4.31 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 33.41 1 8 8 55 3.324E9 40.96 33.41 8 27 3122.87 33.41 8 28 413 45.8 4.45 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 32.92 1 0 21 182 5.502E9 173.94 32.92 21 91 12241.29 32.92 21 91 644 66.0 8.12 HVO_1880 conserved hypothetical protein 32.89 1 6 6 18 1.297E8 11.50 32.89 6 9 822.24 32.89 6 9 225 23.8 4.59 HVO_1901 translation initiation factor aIF-2 gamma subunit 32.85 1 10 10 78 2.620E9 50.72 31.39 9 36 3926.79 32.85 10 42 411 43.9 4.36 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 32.76 1 10 10 38 7.954E8 20.31 32.76 10 19 1613.23 32.76 10 19 348 38.2 4.32 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 32.72 1 28 28 175 1.795E9 139.26 32.72 28 86 9131.18 32.72 28 89 1033 114.3 4.45 HVO_2188 phosphoribosylformylglycinamidine synthase 1 32.14 1 6 6 22 5.381E8 12.60 32.14 6 12 954.42 29.02 5 10 224 23.9 4.36 HVO_2981 uracil phosphoribosyltransferase 31.86 1 5 5 21 1.057E9 11.74 24.34 4 9 948.34 31.86 5 12 226 24.5 4.49 HVO_1391 NUDIX family hydrolase 31.79 1 4 4 8 5.337E7 3.92 26.49 3 3 381.40 31.79 4 5 151 17.4 5.01 HVO_2057 sugar nucleotidyltransferase 31.65 1 9 9 34 1.524E9 22.66 28.85 8 16 1686.56 31.65 9 18 357 37.8 4.44 HVO_1577 conserved hypothetical protein 31.64 1 5 5 12 6.890E8 9.94 31.64 5 7 544.53 31.64 4 5 177 19.4 4.74 HVO_0167 adenosylhomocysteinase 31.54 1 8 8 27 7.853E8 13.77 27.34 7 12 1846.88 26.17 7 15 428 46.6 4.39 HVO_2300 translation initiation factor aIF-5A 31.45 1 3 3 32 4.544E9 24.48 31.45 3 15 2159.98 31.45 3 17 124 14.2 5.22 HVO_1031 thioredoxin-disulfide reductase 30.99 1 7 7 26 6.364E8 20.49 30.99 7 13 1434.74 30.99 7 13 342 37.4 4.46 HVO_2130 IclR family transcription regulator 30.88 1 7 7 23 3.436E8 12.67 22.06 5 10 1377.52 30.88 7 13 272 30.1 5.55 HVO_0717 "cell division protein FtsZ, type I" 30.87 1 10 10 65 3.196E9 55.40 29.02 9 32 4054.04 30.87 10 33 379 39.8 4.40 HVO_2721 amidophosphoribosyltransferase 30.83 1 8 8 38 1.174E9 22.06 28.60 7 18 1443.15 30.83 8 20 493 53.4 4.78 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 30.81 1 8 8 26 4.150E8 7.80 30.81 8 13 759.02 30.81 8 13 422 43.6 4.72 HVO_1576 NAD-dependent epimerase/dehydratase 30.72 1 4 9 42 7.862E8 34.76 27.78 8 21 2326.08 30.72 8 21 306 33.9 4.51 HVO_1660 DisA-N domain protein 30.48 1 6 6 16 6.361E8 13.22 24.16 5 7 822.80 30.48 6 9 269 28.9 4.73 HVO_1544 probable phosphoenolpyruvate-protein phosphoryltransferase 30.47 1 3 3 8 5.716E7 3.78 30.47 3 4 305.20 30.47 3 4 128 13.0 4.31 HVO_0870 proline--tRNA ligase 30.33 1 10 10 54 1.938E9 44.09 27.87 9 26 3169.51 30.33 10 28 488 54.9 4.44 HVO_B0248 probable oxidoreductase (short-chain dehydrogenase family) 30.31 1 5 5 25 3.967E8 17.09 30.31 5 12 1153.34 30.31 5 13 254 26.9 4.42 HVO_0400 conserved hypothetical protein 30.16 1 2 2 7 1.027E8 0.00 30.16 2 3 214.39 30.16 2 4 126 13.9 4.68 HVO_1306 chorismate synthase 30.13 1 6 6 31 9.001E7 31.84 30.13 6 16 1413.50 25.19 5 15 385 41.9 4.83 HVO_0743 probable phosphodiesterase 30.07 1 14 14 66 1.547E9 23.74 30.07 14 31 2871.78 28.51 13 35 449 50.5 4.56 HVO_1018 RecJ domain protein 30.02 1 16 16 75 1.286E9 56.27 28.12 15 38 4533.53 30.02 16 37 633 69.8 4.58 HVO_2347 conserved hypothetical protein 30.00 1 3 3 12 2.395E8 11.61 30.00 3 6 634.70 30.00 3 6 140 15.5 4.37 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 29.97 1 5 5 21 3.728E8 16.84 22.28 4 10 843.90 29.97 5 11 377 39.2 4.18 HVO_C0069 GFO family oxidoreductase 29.94 1 8 8 25 1.724E8 13.43 29.94 8 14 905.35 23.77 7 11 324 36.0 5.10 HVO_0874 beta-lactamase domain protein 29.84 1 16 16 82 2.390E9 55.64 29.84 16 41 4850.95 29.84 16 41 640 71.9 5.14 HVO_1123 thioredoxin-disulfide reductase 29.80 1 8 8 37 8.686E8 21.05 26.65 7 18 1938.38 20.63 7 19 349 37.3 4.32 HVO_0041 ornithine carbamoyltransferase 29.77 1 6 6 27 5.191E8 17.04 29.77 6 14 1135.92 18.06 5 13 299 32.7 4.37 HVO_1546 dihydroxyacetone kinase subunit DhaK 29.52 1 10 10 48 1.657E9 29.71 29.52 10 25 2104.02 29.52 10 23 332 34.8 4.22 HVO_1488 D-gluconate dehydratase 29.37 1 7 10 46 2.137E9 27.91 25.73 9 23 2159.91 26.46 9 23 412 45.8 4.60 HVO_1175 DUF2110 family protein 29.33 1 5 5 19 1.090E9 21.47 29.33 5 10 1350.26 29.33 5 9 225 24.4 4.63 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 29.20 1 9 9 43 2.091E9 38.91 29.20 9 22 2664.78 29.20 9 21 435 46.9 4.63 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 29.17 1 8 8 27 6.225E8 15.39 29.17 8 13 1193.78 29.17 8 14 336 38.0 4.61 HVO_1727 TATA-binding transcription initiation factor 29.03 1 5 6 49 2.765E9 26.19 29.03 6 24 2558.46 29.03 6 25 186 19.9 4.36 HVO_1084 adenylosuccinate lyase 28.94 1 11 11 42 5.514E8 26.56 27.21 10 20 1921.35 28.94 11 22 463 50.8 4.70 HVO_0809 methionine--tRNA ligase 28.92 1 16 16 107 1.508E9 81.82 28.92 16 52 5687.14 28.92 16 55 740 81.9 4.37 HVO_1044 imidazoleglycerol-phosphate synthase subunit HisF 28.89 1 5 5 21 3.850E8 21.10 25.19 4 10 1126.01 28.89 5 11 270 29.1 4.35 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 28.85 1 4 4 12 4.449E8 9.01 19.37 3 6 443.47 19.76 3 6 253 26.0 4.60 HVO_2059 NAD-dependent epimerase/dehydratase 28.71 1 6 6 25 1.120E9 15.82 28.71 6 10 1307.15 28.71 6 15 310 34.1 4.40 HVO_2912 ThiJ/PfpI domain protein 28.36 1 3 3 10 5.441E7 4.66 28.36 3 5 349.28 28.36 3 5 201 20.9 4.36 HVO_1284 GTP cyclohydrolase III 28.35 1 6 6 18 2.389E8 10.66 28.35 6 9 830.34 28.35 6 9 261 28.9 4.70 HVO_1657 phosphoribosylamine--glycine ligase 28.27 1 10 10 50 1.992E9 26.87 28.27 10 22 2670.78 28.27 10 28 428 45.5 4.20 HVO_2675 histidinol dehydrogenase 28.04 1 6 6 30 2.613E8 32.81 22.66 4 14 1979.20 25.47 5 16 428 45.4 4.50 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 27.72 1 4 4 7 1.740E8 4.49 22.28 3 3 356.20 27.72 4 4 184 19.8 5.30 HVO_1853 UspA domain protein 27.70 1 3 3 3 1.012E8 0.00 27.70 3 3 148 16.0 4.58 HVO_0349 DNA-directed RNA polymerase subunit A' 27.66 1 22 22 125 1.500E9 107.23 26.74 21 61 7573.16 26.74 21 64 976 108.8 4.81 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 27.62 1 6 6 29 5.493E8 23.88 27.62 6 14 1316.97 27.62 6 15 362 39.6 4.82 HVO_0484 50S ribosomal protein L10e 27.27 1 4 4 20 1.645E8 11.80 27.27 4 10 948.21 27.27 4 10 176 19.8 8.72 HVO_A0636 YbaK domain protein 27.22 1 3 3 12 4.451E8 8.46 27.22 3 6 541.66 27.22 3 6 158 16.7 4.54 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 27.18 1 9 9 45 6.846E8 31.20 27.18 9 21 2148.44 27.18 9 24 471 51.0 4.48 HVO_0415 repair helicase 27.11 1 14 14 46 1.198E9 29.19 25.65 13 21 2715.69 25.65 13 25 616 69.6 4.70 HVO_0417 metal-dependent carboxypeptidase 27.09 1 11 11 29 5.779E8 14.48 27.09 11 14 1284.70 22.11 10 15 502 57.3 4.42 HVO_1593 PAC2 family protein 27.02 1 3 3 13 3.657E8 4.45 27.02 3 6 352.53 27.02 3 7 248 26.6 4.46 HVO_A0406 conserved hypothetical protein 26.91 1 1 7 36 8.314E8 16.83 26.91 7 18 1642.97 26.91 7 18 405 44.4 5.30 HVO_0393 UvrABC system protein A 26.75 1 20 20 73 4.550E8 49.50 26.75 20 36 3606.75 22.89 19 37 983 108.6 4.82 HVO_0889 FAD-dependent oxidoreductase 26.64 1 2 2 6 6.716E7 5.30 26.64 2 3 468.40 26.64 2 3 214 21.8 3.89 HVO_0788 tryptophan synthase beta subunit 26.54 1 8 8 25 3.776E8 14.04 22.51 7 11 1306.30 26.54 8 14 422 45.7 4.65 HVO_1478 transcription initiation factor TFB 26.50 1 4 8 40 7.121E8 24.74 26.50 8 20 2367.00 26.50 8 20 317 35.7 5.47 HVO_0354 30S ribosomal protein S7 26.47 1 5 5 18 9.451E8 15.90 26.47 5 9 972.16 26.47 5 9 204 22.6 5.14 HVO_2496 adenylate kinase 26.44 1 5 5 15 1.076E9 15.23 18.75 4 7 977.73 26.44 5 8 208 23.1 4.25 HVO_2624 CTP synthase 26.41 1 10 10 48 2.093E9 40.74 24.77 9 23 2767.54 26.41 10 25 549 60.8 4.70 HVO_2781 DNA-directed RNA polymerase subunit D 26.25 1 5 5 50 1.392E9 35.58 22.01 4 26 3225.03 26.25 5 24 259 28.1 4.32 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 26.18 1 7 7 36 3.561E8 33.26 26.18 7 18 2177.59 26.18 7 18 340 38.8 4.58 HVO_1572 DNA gyrase subunit B 26.13 1 15 15 53 4.918E8 26.69 26.13 15 26 2255.90 26.13 15 27 639 71.2 4.83 HVO_1172 NAD-dependent epimerase/dehydratase 26.03 1 5 5 21 1.351E9 14.73 23.49 4 11 1200.86 26.03 5 10 315 34.9 4.34 HVO_2700 AAA-type ATPase (CDC48 subfamily) 25.99 1 15 16 49 4.372E8 28.99 20.42 13 22 2160.04 25.99 16 27 754 82.8 4.75 HVO_1527 glucose-1-phosphate uridylyltransferase 25.93 1 6 6 28 5.223E8 19.29 25.93 6 13 1466.27 25.93 6 15 243 27.5 4.70 47132620 keratin 2a [Homo sapiens] 25.67 1 10 15 81 3.308E9 62.06 25.67 15 40 4935.80 25.67 15 41 639 65.4 8.00 7428712 "keratin 1, type II, cytoskeletal - human" 25.66 1 0 17 154 4.483E9 144.84 25.66 17 77 10235.16 25.66 17 77 643 65.5 6.35 HVO_0661 dCTP deaminase (dUMP-forming) 25.64 1 3 3 10 1.902E8 1.68 25.64 3 5 342.03 25.64 3 5 195 21.2 4.59 HVO_1878 NAD synthase 25.36 1 5 5 14 2.053E8 4.63 16.30 4 5 541.36 25.36 5 9 276 29.6 4.37 HVO_1854 histidine--tRNA ligase 25.29 1 9 9 45 1.132E9 26.89 23.20 8 21 2554.62 25.29 9 24 431 47.1 4.37 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 25.22 1 7 7 31 6.843E8 21.57 25.22 7 15 1657.73 25.22 7 16 226 25.5 4.25 HVO_0511 NAD-dependent epimerase/dehydratase 25.19 1 5 5 22 3.716E8 15.79 25.19 5 11 1175.14 21.76 4 11 262 29.3 4.78 >sp|TRYP_PIG| 25.11 1 4 4 126 4.504E10 163.84 25.11 4 63 10466.92 25.11 4 63 231 24.4 7.18 HVO_1134 conserved hypothetical protein 25.10 1 13 13 27 2.392E8 16.54 21.40 11 14 970.04 23.91 12 13 757 80.6 4.35 HVO_0034 acyl-CoA thioester hydrolase 25.00 1 3 3 12 1.667E8 7.89 25.00 3 6 559.44 25.00 3 6 164 18.3 4.65 HVO_0401 UspA domain protein 25.00 1 2 2 14 1.466E9 13.54 25.00 2 7 841.87 25.00 2 7 152 16.4 4.79 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 24.87 1 9 9 32 4.261E8 38.58 24.87 9 16 2374.10 24.87 9 16 599 65.3 4.51 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 24.80 1 9 9 38 5.078E8 35.86 21.88 8 19 2273.24 24.80 9 19 512 53.8 4.78 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 24.60 1 5 5 26 1.743E9 27.24 24.60 5 12 2263.68 24.60 5 14 252 26.0 4.39 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 24.52 1 8 8 23 3.118E8 14.62 18.82 7 10 1159.04 24.52 8 13 473 50.8 4.58 HVO_1866 uridylate kinase 24.47 1 4 4 15 7.095E8 11.75 18.99 3 7 831.23 24.47 4 8 237 24.6 4.42 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 24.45 1 7 7 27 2.013E8 20.72 21.70 6 13 1902.40 24.45 7 14 364 39.3 4.35 HVO_1932 2-D-hydroxyacid dehydrogenase 24.03 1 6 6 20 1.001E8 9.19 24.03 6 10 791.29 24.03 6 10 308 33.0 4.60 HVO_0206 alanine--tRNA ligase 23.97 1 19 19 76 6.082E8 46.59 20.93 16 35 3710.63 23.97 19 41 922 102.4 4.54 HVO_1690 DHH family phosphoesterase 23.92 1 9 9 37 2.528E8 35.94 23.92 8 18 2171.47 23.92 9 19 485 52.1 4.48 HVO_2865 methylenetetrahydrofolate dehydrogenase / methenyltetrahydrofolate cyclohydrolase 23.91 1 5 5 44 1.637E9 37.54 23.91 5 22 2157.25 23.91 5 22 297 31.3 4.36 HVO_1510 2-isopropylmalate synthase 23.86 1 7 7 23 1.691E9 13.13 23.86 7 12 1299.19 14.32 5 11 440 47.7 4.82 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 23.84 1 7 7 40 1.293E9 34.98 23.84 7 20 2442.15 23.84 7 20 453 47.5 4.63 HVO_0357 ACT domain protein 23.81 1 4 4 17 8.758E8 14.43 23.81 4 9 742.99 23.81 4 8 189 20.2 4.59 HVO_1573 DNA gyrase subunit A 23.67 1 18 18 62 8.916E8 48.32 23.67 18 31 3258.57 22.27 17 31 862 94.8 4.56 HVO_1097 diaminopimelate epimerase 23.61 1 4 4 17 3.161E8 6.54 16.32 3 9 680.22 23.61 4 8 288 29.9 4.48 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 23.55 1 10 10 31 6.242E8 27.81 23.55 10 16 1881.20 22.01 9 15 586 63.4 4.70 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 23.24 1 8 8 54 2.104E9 44.18 23.24 8 26 3341.97 23.24 8 28 370 41.9 4.48 HVO_0388 homolog to ribonuclease R 23.23 1 10 10 42 1.973E8 41.99 23.23 10 21 2576.64 23.23 10 21 439 50.3 4.73 HVO_0549 2-keto-3-deoxygluconate kinase 23.13 1 6 7 21 3.130E8 8.80 19.38 6 10 970.23 21.25 6 11 320 34.1 4.34 HVO_0601 homoserine dehydrogenase 23.10 1 5 6 30 4.778E8 20.46 23.10 6 15 1749.95 23.10 6 15 316 32.2 4.25 HVO_2706 translation initiation factor aIF-2B delta subunit 23.05 1 3 3 7 3.935E8 3.98 14.18 2 3 321.23 23.05 3 4 282 30.7 4.42 HVO_2436 malic enzyme (NADP) 23.04 1 13 15 47 6.673E8 43.26 23.04 15 25 2730.98 21.30 12 22 751 81.4 4.55 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 22.82 1 6 6 16 2.303E8 6.27 22.82 6 9 692.46 18.32 5 7 333 36.7 4.56 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 22.82 1 9 9 36 6.521E8 24.06 22.82 9 18 1972.57 20.13 8 18 447 48.5 4.56 HVO_0452 leucine--tRNA ligase 22.76 1 14 14 43 5.582E8 22.66 17.12 12 21 2169.92 22.76 14 22 958 109.5 4.37 HVO_0911 GTP-binding protein Drg 22.76 1 7 7 18 7.677E7 6.45 19.51 6 9 617.66 22.76 7 9 369 40.5 4.81 HVO_A0496 UspA domain protein 22.76 1 6 6 16 4.518E8 1.69 22.76 6 9 417.67 19.66 5 7 290 31.4 4.60 HVO_1459 ThuA family protein 22.69 1 3 3 12 7.485E8 10.83 22.69 3 6 812.85 22.69 3 6 238 26.8 4.67 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 22.69 1 8 8 47 2.554E9 46.56 22.69 8 24 2602.64 22.69 7 23 357 40.3 4.40 HVO_3009 UspA domain protein 22.48 1 2 2 2 9.077E8 0.00 22.48 2 2 129 13.8 4.55 HVO_1125 cysteine--tRNA ligase 22.47 1 8 8 24 3.569E8 12.34 18.83 7 12 1088.04 20.45 7 12 494 55.2 4.56 HVO_1373 acyl-CoA dehydrogenase 22.45 1 5 5 12 3.991E8 4.68 13.84 3 5 594.25 22.45 5 7 383 42.5 4.61 HVO_2779 50S ribosomal protein L18e 22.41 1 2 2 10 3.582E7 6.66 22.41 2 5 420.62 22.41 2 5 116 12.7 8.50 HVO_2726 glutamate--tRNA ligase 22.39 1 10 10 43 9.107E8 25.18 22.39 10 21 2202.49 22.39 10 22 585 65.2 4.58 HVO_1048 phosphoribosylformylglycinamidine synthase 2 22.36 1 10 10 60 9.233E8 66.37 21.37 9 29 3983.69 22.36 10 31 702 72.9 4.18 HVO_0573 endonuclease IV 22.34 1 4 4 17 6.807E8 8.94 22.34 4 8 821.12 22.34 4 9 291 31.4 4.44 HVO_0602 3-dehydroquinate dehydratase 22.27 1 4 4 12 1.176E8 2.15 22.27 4 6 521.70 22.27 4 6 247 27.3 4.51 HVO_1778 catalase-peroxidase 22.14 1 11 11 63 2.162E9 45.68 20.75 10 31 3579.61 22.14 11 32 718 80.0 4.31 HVO_2580 L-aspartate oxidase 21.97 1 7 7 23 1.162E8 17.88 21.97 7 12 1196.89 21.97 7 11 537 55.8 4.63 HVO_0792 3-dehydroquinate synthase type II 21.94 1 7 7 32 1.064E9 27.12 21.94 7 16 1715.95 21.94 7 16 392 43.1 4.44 HVO_2205 arNOG06768 family NADH-binding domain protein 21.93 1 5 5 17 5.470E7 8.62 21.93 5 8 977.10 21.93 5 9 301 32.0 5.00 HVO_1654 cysteine synthase 21.90 1 4 4 12 7.662E8 7.39 21.90 4 6 434.22 21.90 4 6 306 32.3 4.32 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 21.90 1 18 18 90 8.587E8 80.94 20.43 17 44 5364.38 21.90 18 46 1082 117.2 4.32 HVO_1623 conserved hypothetical protein 21.81 1 5 5 19 2.500E8 11.18 21.81 5 9 913.39 21.81 5 10 298 32.8 4.56 HVO_1631 S-adenosyl-L-methionine:L-histidine 3-amino-3-carboxypropyltransferase 21.80 1 6 6 18 1.043E8 11.15 18.60 5 8 1194.39 21.80 6 10 344 39.1 4.73 HVO_0867 HD family hydrolase 21.74 1 4 4 10 1.373E8 6.44 21.74 4 5 426.75 21.74 4 5 230 26.2 4.78 HVO_1076 sugar nucleotidyltransferase 21.74 1 5 5 19 7.490E8 13.24 21.74 5 10 989.14 21.74 5 9 322 35.8 4.20 HVO_2562 50S ribosomal protein L23 21.69 1 2 2 2 1.758E7 167.21 21.69 2 2 83 9.4 5.48 HVO_2690 GFO family oxidoreductase 21.58 1 7 7 24 1.102E9 9.70 19.13 6 12 1050.05 21.58 7 12 366 40.0 4.60 HVO_1571 DNA topoisomerase VI subunit B 21.55 1 14 14 45 5.528E8 24.73 20.68 13 22 1918.72 19.30 13 23 798 87.4 4.73 HVO_2712 3'-5' RNA ligase 21.40 1 7 7 18 3.015E8 6.65 19.55 6 8 588.83 21.40 7 10 486 53.4 4.92 HVO_2454 anthranilate synthase component I 21.37 1 8 8 26 7.619E8 19.90 19.08 7 13 1339.54 19.27 7 13 524 55.9 4.56 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 21.33 1 7 7 33 6.709E8 26.01 21.33 7 17 1588.97 18.44 6 16 347 36.8 4.93 HVO_0519 replication protein A 21.33 1 8 8 28 5.010E8 7.68 18.43 7 13 1255.31 21.33 8 15 483 51.0 4.13 HVO_2688 TrmB family transcription regulator 21.25 1 5 5 29 9.253E8 33.44 21.25 5 15 2244.31 21.25 5 14 353 39.3 4.58 HVO_A0432 conserved hypothetical protein 21.23 1 0 6 27 4.762E8 14.19 21.23 6 14 1384.11 21.23 6 13 405 44.5 5.24 HVO_0008 aspartate kinase 21.17 1 6 6 51 4.021E9 32.25 21.17 6 24 2489.95 21.17 6 27 392 41.7 4.46 HVO_2239 UspA domain protein 21.13 1 3 3 12 8.938E8 13.05 21.13 3 6 723.05 21.13 3 6 142 15.4 4.16 HVO_0243 threonine aldolase 21.11 1 4 4 7 5.913E7 6.17 15.84 3 3 399.18 21.11 4 4 341 35.6 4.55 HVO_0424 ABC-type transport system ATP-binding protein 21.03 1 10 10 37 4.553E8 31.90 21.03 10 18 1865.38 21.03 10 19 604 67.2 4.49 HVO_0787 indole-3-glycerol-phosphate synthase 20.72 1 3 3 9 1.183E8 6.08 20.72 3 5 378.18 16.33 2 4 251 26.7 4.44 HVO_1370 gamma-glutamyl phosphate reductase 20.72 1 7 7 27 9.467E8 21.14 20.72 7 14 1608.41 16.22 6 13 444 48.1 4.34 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 20.72 1 5 5 13 7.350E8 5.88 20.72 5 6 516.58 20.72 5 7 415 44.4 4.41 HVO_2560 30S ribosomal protein S19 20.71 1 2 2 8 1.945E7 8.63 20.71 2 4 640.79 20.71 2 4 140 16.0 5.57 HVO_2564 50S ribosomal protein L3 20.71 1 5 5 13 9.258E7 10.87 20.71 5 7 500.55 17.46 4 6 338 37.2 6.68 HVO_0360 30S ribosomal protein S10 20.59 1 2 2 6 1.333E8 0.00 20.59 2 3 101.20 20.59 2 3 102 11.5 4.88 HVO_1020 HEAT-PBS family protein 20.53 1 6 6 21 1.534E8 23.21 20.53 6 11 1421.92 20.53 6 10 419 45.5 3.95 HVO_1295 histidinol-phosphate aminotransferase 20.22 1 5 5 14 2.670E8 4.72 13.02 3 5 590.13 20.22 5 9 361 39.4 4.51 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 20.09 1 12 12 46 1.149E9 31.43 18.51 11 21 2440.02 17.50 10 25 697 74.5 4.13 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 20.04 1 6 6 22 2.254E8 17.30 20.04 6 11 1198.24 20.04 6 11 454 48.5 4.46 HVO_1164 HD family hydrolase 20.00 1 5 5 15 3.321E8 3.66 14.81 4 6 543.11 20.00 5 9 270 29.8 4.87 HVO_2068 "FtsZ family protein, type III" 20.00 1 4 4 12 3.397E8 12.50 20.00 4 6 851.07 20.00 4 6 370 38.7 4.49 HVO_0233 ribose-phosphate pyrophosphokinase 19.79 1 3 3 10 5.227E8 0.00 19.79 3 5 309.45 19.79 3 5 283 29.6 4.40 HVO_0795 transcription initiation factor TFB 19.70 1 3 5 13 1.555E8 9.38 19.70 5 7 548.82 16.72 4 6 335 37.4 5.59 HVO_2777 30S ribosomal protein S9 19.70 1 3 3 7 7.360E7 3.72 19.70 3 3 359.45 19.70 3 4 132 14.7 9.74 HVO_B0149 oleate hydratase 19.70 1 6 7 20 5.423E8 9.33 13.32 6 10 708.66 17.26 6 10 533 60.1 4.64 HVO_1338 replication protein A 19.67 1 5 5 20 5.644E8 16.67 19.67 5 10 955.02 19.67 5 10 427 46.0 4.36 HVO_A0266 IclR family transcription regulator 19.61 1 4 4 13 1.460E8 13.44 16.86 3 6 832.79 19.61 4 7 255 27.7 6.05 HVO_1534 probable S-adenosylmethionine-dependent methyltransferase 19.57 1 2 2 10 3.162E8 0.00 19.57 2 5 159.99 19.57 2 5 184 20.0 4.75 HVO_1649 methionine adenosyltransferase 19.40 1 5 5 18 2.668E8 9.18 19.40 5 9 1086.06 19.40 5 9 402 43.5 4.45 HVO_0407 conserved hypothetical protein 19.35 1 2 2 3 2.487E8 2.05 19.35 2 3 124 13.4 4.44 HVO_0043 acetylornithine aminotransferase 19.31 1 5 5 26 2.164E9 24.59 15.61 4 13 1598.96 16.67 4 13 378 39.7 4.67 HVO_1189 aldehyde dehydrogenase 19.29 1 8 8 46 1.001E9 41.01 15.16 7 23 2387.47 19.29 7 23 508 56.1 4.59 HVO_2189 phosphoribosylformylglycinamidine synthase component PurS 19.28 1 1 2 4 1.207E7 1.85 19.28 2 2 119.64 19.28 2 2 83 9.3 4.50 HVO_0017 conserved hypothetical protein 19.27 1 3 3 8 3.520E8 5.44 19.27 3 4 405.37 19.27 3 4 192 21.9 4.50 HVO_1783 conserved hypothetical protein 19.20 1 3 3 8 4.506E7 1.77 19.20 3 4 342.42 19.20 3 4 224 24.1 5.90 HVO_0109 cysteine desulfurase 19.01 1 7 7 22 8.444E8 11.97 19.01 7 11 1166.16 19.01 7 11 426 46.8 4.56 HVO_0292 replication protein A 18.97 1 4 4 18 2.553E8 17.89 18.97 4 9 1202.45 18.97 4 9 311 34.6 4.31 HVO_0697 PAC2 family protein 18.82 1 2 2 15 5.610E8 12.42 18.82 2 8 645.04 18.82 2 7 255 27.4 4.08 HVO_2547 50S ribosomal protein L32e 18.72 1 3 3 16 2.261E8 18.71 18.72 3 8 1508.93 18.72 3 8 235 25.8 4.75 HVO_2879 ornithine cyclodeaminase 18.67 1 4 4 6 2.577E8 2.17 8.43 2 2 234.73 15.06 3 4 332 34.6 4.45 HVO_2763 homolog to ribonuclease Z 18.55 1 3 4 9 2.280E8 1.64 16.13 3 3 303.53 18.55 4 6 248 26.6 4.53 HVO_0214 L-lactate dehydrogenase 18.44 1 6 6 44 2.636E9 38.74 18.44 6 22 3167.49 18.44 6 22 320 34.5 4.49 HVO_1371 glutamate 5-kinase 18.27 1 3 3 13 4.861E8 4.30 18.27 3 6 725.55 18.27 3 7 301 32.0 4.25 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 18.22 1 3 3 10 2.500E8 6.80 18.22 3 5 365.98 18.22 3 5 269 28.3 4.49 HVO_2313 siroheme decarboxylase AhbB 18.13 1 3 3 10 3.253E8 13.09 18.13 3 5 524.86 18.13 3 5 353 39.6 4.64 HVO_2947 phenylalanine--tRNA ligase beta subunit 18.07 1 7 7 25 4.936E8 11.48 14.39 5 9 1353.82 18.07 7 16 570 63.3 4.46 HVO_0699 translation initiation factor aIF-2 alpha subunit 18.05 1 5 5 23 4.307E8 8.24 18.05 5 11 1141.96 18.05 5 12 266 29.5 4.46 HVO_2948 phenylalanine--tRNA ligase alpha subunit 18.04 1 5 5 27 5.086E8 19.88 18.04 5 13 1138.36 18.04 5 14 499 55.1 4.41 HVO_1025 acetyl-CoA C-acyltransferase 18.02 1 4 4 14 4.591E8 14.16 18.02 4 7 740.50 18.02 4 7 383 40.7 4.56 HVO_0466 citrate (si)-synthase 17.94 1 6 6 42 9.826E8 28.44 16.62 5 20 2065.42 17.94 6 22 379 41.8 4.55 HVO_2156 UspA domain protein 17.94 1 4 4 20 7.610E8 18.99 17.94 4 10 1431.73 17.94 4 10 301 31.6 4.69 HVO_2614 uridine phosphorylase 17.77 1 3 3 19 1.347E9 14.24 17.77 3 9 870.80 17.77 3 10 242 25.8 4.30 HVO_B0018 ParA domain protein 17.77 1 3 3 9 9.243E7 0.00 17.77 3 5 312.67 14.63 2 4 287 31.7 4.74 HVO_2782 30S ribosomal protein S11 17.69 1 2 2 14 3.769E8 11.29 17.69 2 7 781.35 17.69 2 7 130 13.4 8.56 HVO_2716 acyl-CoA dehydrogenase 17.59 1 4 4 10 2.146E7 4.52 17.59 4 5 429.39 17.59 4 5 381 41.3 4.65 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 17.49 1 8 8 32 9.006E8 17.10 17.49 8 15 1441.90 17.49 8 17 526 57.2 4.31 HVO_0406 RNA-binding protein AU-1 17.31 1 6 6 17 1.336E8 8.81 17.31 6 8 650.19 17.31 6 9 468 49.9 4.53 HVO_0541 aconitate hydratase 17.27 1 9 9 27 1.157E9 17.14 14.93 8 14 1107.73 13.33 7 13 938 102.1 4.40 HVO_1547 isoleucine--tRNA ligase 17.26 1 12 12 50 9.647E8 38.03 16.30 11 26 2654.21 12.94 10 24 1043 117.9 4.30 HVO_1496 phosphotransferase system component I 17.17 1 7 7 28 1.734E8 14.33 17.17 7 14 1253.77 17.17 7 14 565 60.3 4.21 HVO_0829 peptidase S9 family protein 17.11 1 5 5 22 2.538E8 16.17 17.11 5 12 1346.35 14.97 4 10 608 67.4 4.54 HVO_2708 YfiH family protein 17.08 1 4 4 13 3.776E8 6.45 17.08 4 7 392.62 12.73 3 6 322 35.4 4.35 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 16.89 1 6 6 22 1.063E9 11.48 16.89 6 11 1001.71 16.89 6 11 373 40.2 4.44 HVO_2348 GTP cyclohydrolase MptA 16.88 1 4 4 9 1.254E8 0.00 10.71 3 4 269.39 16.88 4 5 308 33.5 4.68 HVO_2507 Lrp/AsnC family transcription regulator 16.79 1 3 3 8 8.657E7 6.53 16.79 3 4 371.86 16.79 3 4 137 15.5 4.67 HVO_A0133 conserved hypothetical protein 16.78 1 4 4 12 1.870E8 5.92 15.07 3 5 520.02 16.78 4 7 292 30.8 5.17 HVO_2225 AstE family protein 16.72 1 3 3 11 6.866E8 4.97 16.72 3 5 562.42 16.72 3 6 341 36.9 4.53 HVO_1871 UPF0447 family protein 16.57 1 7 7 26 5.944E8 13.39 13.17 6 12 1291.56 16.57 7 14 501 56.1 4.59 HVO_0123 signal recognition particle 54K protein 16.56 1 4 4 10 1.375E8 2.88 9.03 3 4 360.21 16.56 4 6 465 50.9 4.50 HVO_2945 valine--tRNA ligase 16.55 1 13 13 59 1.217E9 36.18 14.25 11 27 3501.34 16.55 13 32 870 98.9 4.36 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 16.51 1 5 5 15 1.571E8 10.41 16.51 5 7 469.69 16.51 5 8 430 45.1 4.50 HVO_A0274 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 16.48 1 3 3 8 8.767E7 0.00 16.48 3 4 294.66 16.48 3 4 267 29.1 4.63 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 16.47 1 0 2 8 1.788E9 0.00 16.47 2 4 389.72 16.47 2 4 85 10.0 5.94 HVO_0334 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 16.46 1 3 3 6 2.428E8 1.80 16.46 3 3 140.86 11.39 2 3 237 25.4 4.46 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 16.40 1 3 3 17 1.521E8 6.18 9.52 2 7 755.75 16.40 3 10 189 21.7 4.46 HVO_1592 DnaJ/DnaK ATPase stimulator GrpE 16.02 1 3 3 13 7.389E7 11.12 16.02 3 7 676.15 16.02 3 6 231 25.0 4.25 HVO_2554 50S ribosomal protein L14 15.91 1 3 3 8 2.960E8 4.32 15.91 3 4 428.50 15.91 3 4 132 14.2 9.76 HVO_A0307 Lrp/AsnC family transcription regulator 15.82 1 2 2 4 2.784E7 3.46 15.82 2 2 183.47 15.82 2 2 177 19.4 4.39 HVO_0812 phosphoenolpyruvate synthase 15.77 1 8 8 30 2.024E8 30.02 15.77 8 15 1587.67 15.77 8 15 761 83.1 4.63 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 15.69 1 4 4 24 3.802E8 5.15 15.69 4 12 1055.70 15.69 4 12 357 39.8 4.41 HVO_0208 glutamine amidotransferase (homolog to GMP synthase subunit A) 15.61 1 2 2 4 2.018E7 2.22 15.61 2 2 85.53 15.61 2 2 237 26.2 4.70 HVO_2790 ATP-binding protein Mrp 15.61 1 3 3 16 2.056E8 8.24 15.61 3 8 503.09 15.61 3 8 346 36.8 4.50 HVO_0054 glycine--tRNA ligase 15.49 1 6 6 22 1.825E9 18.54 13.13 5 11 1464.25 15.49 6 11 594 64.9 4.21 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 15.40 1 7 7 19 6.853E8 5.94 15.40 7 9 850.95 15.40 7 10 461 50.7 4.73 HVO_2309 probable pterin-4-alpha-carbinolamine dehydratase 15.38 1 1 2 2 1.077E8 129.82 15.38 2 2 91 10.4 4.07 HVO_1531 UDP-glucose 6-dehydrogenase 15.35 1 5 5 18 1.697E8 4.05 15.35 5 9 538.57 15.35 5 9 430 45.9 4.50 HVO_0158 TATA-binding transcription initiation factor 15.34 1 2 3 11 6.155E8 4.70 15.34 3 6 458.74 15.34 3 5 189 20.3 4.22 HVO_0894 acyl-CoA synthetase 15.26 1 3 6 13 1.822E8 7.02 12.99 5 6 527.63 15.26 6 7 662 74.3 4.48 HVO_0042 acetylornithine deacetylase 15.22 1 4 4 12 7.443E8 8.88 15.22 4 6 587.70 15.22 4 6 381 41.0 4.34 HVO_1073 ThiJ/PfpI family protein 15.18 1 3 3 10 7.204E7 10.26 15.18 3 5 473.05 15.18 3 5 224 23.9 4.12 HVO_1098 diaminopimelate decarboxylase 15.18 1 5 5 10 2.344E8 4.82 13.49 4 4 366.30 15.18 5 6 415 44.4 5.02 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 15.09 1 3 3 12 1.713E8 10.14 15.09 3 6 475.88 15.09 3 6 265 28.7 4.87 HVO_1087 UspA domain protein 14.89 1 3 3 9 1.044E8 9.13 8.51 2 4 544.15 14.89 3 5 141 15.2 4.98 HVO_B0057 precorrin-3B C17-methyltransferase 14.83 1 2 2 5 1.876E8 722.81 14.83 2 5 344 36.3 4.31 HVO_1508 acetolactate synthase large subunit 14.82 1 5 5 26 4.477E8 17.73 14.82 5 13 1350.64 14.82 5 13 587 62.3 4.36 HVO_1562 proteasome beta subunit 14.81 1 3 3 16 1.827E8 10.32 14.81 3 8 852.61 14.81 3 8 243 26.0 4.63 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 14.77 1 3 3 7 2.251E8 3.16 14.77 3 4 148.20 5.96 2 3 386 42.1 4.49 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 14.75 1 3 3 8 6.387E7 0.00 12.46 2 3 291.54 14.75 3 5 305 32.7 4.56 HVO_2481 HD family hydrolase 14.62 1 3 3 5 9.872E7 0.00 14.62 3 3 94.69 8.97 2 2 390 42.7 6.14 HVO_2717 alanine--tRNA ligase 14.57 1 5 5 21 2.210E8 14.29 11.56 4 10 1249.33 14.57 5 11 398 41.6 4.39 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 14.55 1 3 3 14 3.468E8 13.44 14.55 3 7 787.41 10.91 2 7 330 36.3 4.35 HVO_2961 dihydrolipoyl dehydrogenase 14.53 1 6 6 20 2.012E8 14.52 14.53 6 10 880.77 14.53 6 10 475 49.9 4.41 HVO_B0061 precorrin-2 C20-methyltransferase 14.47 1 3 3 12 6.742E7 7.78 14.47 3 6 455.23 14.47 3 6 235 25.3 4.63 HVO_1946 "translation initiation factor aIF-1 (SUI1 protein, bacterial-type IF3)" 14.43 1 2 2 2 1.339E8 0.00 14.43 2 2 97 10.8 4.53 HVO_1823 UspA domain protein 14.38 1 2 2 10 2.862E8 8.58 14.38 2 4 670.06 14.38 2 6 153 16.4 4.60 HVO_2305 molybdenum cofactor biosynthesis protein MoeA 14.35 1 6 6 12 1.305E8 4.84 10.25 5 6 439.87 12.78 5 6 634 66.1 4.54 HVO_2008 archaeosine synthase 14.19 1 5 5 12 2.312E8 6.52 14.19 5 7 453.49 12.48 4 5 585 64.9 4.81 HVO_0916 diphthine synthase 14.13 1 2 2 2 5.374E8 3.00 14.13 2 2 269 29.1 4.54 HVO_2435 peptidase M24 family protein 14.13 1 4 4 9 9.609E7 2.13 9.78 3 4 396.93 14.13 4 5 368 40.0 4.53 HVO_0970 ribulose-bisphosphate carboxylase large subunit 14.01 1 6 6 32 1.520E8 19.33 14.01 6 16 1547.09 14.01 6 16 414 43.9 4.59 HVO_2266 hypothetical protein 14.00 1 4 4 9 1.528E8 1.85 14.00 4 4 306.51 7.91 3 5 493 56.7 4.54 HVO_0719 transcription elongation factor Spt5/NusG 14.00 1 2 2 4 1.078E8 362.35 14.00 2 4 150 16.3 4.50 HVO_1187 conserved hypothetical protein 13.99 1 2 2 8 9.354E7 2.81 13.99 2 4 265.40 13.99 2 4 143 16.4 4.86 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 13.84 1 3 3 9 4.079E7 6.90 13.84 3 6 148.77 13.84 3 3 383 42.0 4.49 HVO_0234 conserved hypothetical protein 13.82 1 2 2 6 4.911E7 1.89 13.82 2 3 174.99 13.82 2 3 275 28.1 4.48 HVO_1610 conserved hypothetical protein 13.78 1 2 2 4 0.000E0 5.48 13.78 2 2 167.93 13.78 2 2 283 30.5 4.55 HVO_1809 isochorismatase family protein 13.68 1 2 2 2 1.078E8 80.64 13.68 2 2 190 21.0 4.55 HVO_0647 GMP synthase (glutamine-hydrolyzing) subunit A 13.66 1 2 2 6 1.488E8 3.75 13.66 2 3 319.33 13.66 2 3 183 20.0 4.21 HVO_2421 probable DNA-binding protein 13.62 1 3 3 6 4.762E7 1.61 7.23 2 2 283.96 13.62 3 4 235 25.8 4.89 HVO_1412 diphosphomevalonate decarboxylase 13.58 1 5 5 27 1.322E9 9.32 13.58 5 14 1059.24 13.58 5 13 324 35.4 4.78 HVO_0681 DNA topoisomerase I 13.57 1 9 9 19 2.742E8 8.98 10.48 7 10 943.72 9.17 6 9 840 93.6 4.58 HVO_0694 probable phosphoribosyltransferase 13.50 1 3 3 6 4.495E7 1.62 13.50 3 3 189.06 13.50 3 3 237 27.0 4.32 HVO_C0001 Orc1-type DNA replication protein 13.48 1 6 6 18 1.166E8 11.33 11.27 5 9 735.23 13.48 6 9 408 45.2 4.97 HVO_1816 dihydroorotase 13.29 1 5 5 12 9.400E7 1.88 13.29 5 6 325.71 13.29 5 6 429 45.4 4.40 HVO_2759 peptidase M42 family protein 13.28 1 3 3 7 2.998E8 7.98 13.28 3 4 228.09 9.60 2 3 354 37.0 4.40 HVO_A0331 D-galactonate dehydratase 13.28 1 3 3 7 1.145E8 7.37 8.07 2 3 425.01 13.28 3 4 384 42.8 4.83 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 13.24 1 5 5 14 1.250E8 6.41 13.24 5 7 745.76 13.24 5 7 423 43.9 4.31 HVO_1491 HAD superfamily hydrolase 13.24 1 4 4 12 8.861E7 8.29 13.24 4 6 569.15 13.24 4 6 408 44.4 4.60 HVO_0207 alpha/beta hydrolase fold protein 13.18 1 2 2 4 1.456E7 2.59 13.18 2 2 119.87 13.18 2 2 258 27.0 4.42 HVO_0044 acetylglutamate kinase 13.15 1 3 3 15 3.016E8 14.47 13.15 3 7 1145.34 13.15 3 8 327 33.2 4.49 HVO_2508 carbamoyl-phosphate synthase (glutamine-hydrolyzing) small subunit 13.06 1 3 3 18 5.366E8 12.32 13.06 3 9 1001.20 13.06 3 9 360 38.5 4.45 HVO_0600 ACT domain protein 12.99 1 2 2 4 5.031E8 0.00 12.99 2 2 214.58 12.99 2 2 177 19.2 4.44 HVO_2270 type I restriction-modification system DNA-methyltransferase RmeM 12.93 1 4 4 11 1.686E8 5.21 12.93 4 6 454.99 9.70 3 5 464 53.1 4.54 HVO_1824 conserved hypothetical protein 12.82 1 3 3 7 2.040E8 6.66 6.53 2 3 357.06 12.82 3 4 429 47.4 4.20 HVO_B0066 Lrp/AsnC family transcription regulator 12.80 1 2 2 4 0.000E0 4.24 12.80 2 2 160.02 12.80 2 2 164 18.5 4.41 HVO_1268 conserved hypothetical protein 12.66 1 2 2 4 4.687E7 4.55 12.66 2 2 267.64 12.66 2 2 237 26.4 5.21 HVO_2427 replication factor C large subunit 12.50 1 5 5 13 1.206E8 10.66 10.04 4 6 493.74 12.50 5 7 488 53.4 4.67 HVO_1594 tRNA/rRNA cytosine-C5-methylase 12.46 1 3 3 10 1.019E8 7.53 12.46 3 5 510.73 12.46 3 5 313 34.6 4.69 HVO_1372 pyrroline-5-carboxylate reductase 12.45 1 3 3 10 2.405E8 8.54 12.45 3 5 685.99 12.45 3 5 257 26.8 4.01 HVO_2622 probable oxidoreductase (aldo-keto reductase family protein) 12.41 1 3 3 8 9.003E7 1.84 12.41 3 4 407.84 12.41 3 4 266 29.7 4.32 HVO_2883 conserved hypothetical protein 12.39 1 6 6 18 1.775E8 9.90 9.26 4 8 861.65 12.39 6 10 702 78.9 4.48 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 12.38 1 12 12 32 4.175E8 12.14 11.21 11 15 1424.48 12.38 12 17 1284 141.2 4.35 HVO_1570 DNA topoisomerase VI subunit A 12.30 1 3 3 4 1.228E8 2.01 9.56 2 2 215.02 6.56 2 2 366 41.8 4.63 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 12.29 1 0 6 34 1.495E9 17.66 12.29 6 17 2167.97 12.29 6 17 472 51.6 5.16 HVO_0087 porphobilinogen synthase 12.23 1 4 4 15 1.448E8 0.00 12.23 4 7 470.36 12.23 4 8 327 35.3 4.72 HVO_B0382 TATA-binding transcription initiation factor 12.23 1 2 2 4 7.422E7 0.00 12.23 2 4 188 20.1 4.12 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 12.18 1 3 3 13 2.170E8 9.95 12.18 3 6 647.88 12.18 3 7 427 45.4 4.56 HVO_2380 AAA-type ATPase (CDC48 subfamily) 12.11 1 7 7 14 1.197E8 7.37 8.75 6 7 379.92 10.23 6 7 743 81.9 4.82 HVO_2784 30S ribosomal protein S13 11.98 1 2 2 6 5.102E8 1.75 11.98 2 3 197.16 11.98 2 3 167 18.9 5.17 HVO_0997 peptidase M24 family protein 11.96 1 2 2 5 5.665E7 1.82 11.96 2 2 202.16 11.96 2 3 368 39.9 4.49 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 11.90 1 4 4 11 1.115E8 1.94 11.90 4 5 386.17 11.90 4 6 378 39.8 4.45 HVO_2467 NADPH:quinone reductase 11.84 1 2 2 7 1.703E8 0.00 11.84 2 3 342.02 11.84 2 4 321 33.0 4.51 HVO_2412 Lrp/AsnC family transcription regulator 11.80 1 2 2 4 9.812E7 0.00 11.80 2 2 185.53 11.80 2 2 161 17.7 4.55 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 11.76 1 4 4 13 5.253E7 10.59 9.50 3 6 714.67 11.76 4 7 442 46.9 4.58 HVO_0195 ribose-5-phosphate isomerase 11.74 1 2 2 4 3.762E8 2.11 11.74 2 2 125.86 11.74 2 2 230 23.2 4.54 HVO_0228 ParA domain protein 11.74 1 2 2 4 2.791E8 477.97 11.74 2 4 247 24.6 4.16 HVO_2501 alpha/beta hydrolase fold protein 11.71 1 3 3 7 2.586E7 5.07 11.71 3 4 234.72 9.49 2 3 316 35.3 5.72 HVO_0979 NADH dehydrogenase-like complex subunit B 11.59 1 3 3 8 2.117E8 5.59 11.59 3 4 366.95 11.59 3 4 233 26.1 5.01 HVO_1685 conserved hypothetical protein 11.59 1 5 5 15 1.689E8 8.05 11.59 5 8 530.84 9.96 4 7 492 54.5 5.74 HVO_2662 homolog to lactoylglutathione lyase 11.55 1 3 3 6 4.019E7 1.87 11.55 3 3 152.84 8.81 2 3 329 36.5 4.48 HVO_1348 probable YjeF family carbohydrate kinase 11.51 1 3 3 6 1.164E8 1.62 11.51 3 3 122.95 11.51 3 3 478 48.8 4.45 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 11.47 1 4 4 9 8.502E7 1.60 7.36 3 4 253.88 10.10 3 5 584 63.3 4.79 HVO_2001 tRNA-guanine(15) transglycosylase 11.43 1 3 3 12 5.788E7 11.05 11.43 3 6 533.42 11.43 3 6 516 56.3 4.59 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 11.38 1 5 5 21 5.029E8 16.85 11.38 5 10 988.87 11.38 5 11 615 67.6 4.88 HVO_2072 S-layer glycoprotein 11.37 1 4 4 51 2.143E9 36.00 11.37 4 24 1549.50 11.37 4 27 827 85.1 3.65 HVO_1847 oligoendopeptidase PepF 11.35 1 5 5 14 2.214E8 3.83 8.85 4 6 619.17 11.35 5 8 599 68.5 4.41 HVO_2417 conserved hypothetical protein 11.28 1 2 2 8 4.762E8 5.49 11.28 2 4 311.29 11.28 2 4 195 21.6 3.65 HVO_2456 anthranilate phosphoribosyltransferase 11.18 1 2 2 7 2.289E8 1.73 11.18 2 3 266.82 11.18 2 4 331 33.8 4.35 HVO_1465 naphthoate synthase 11.15 1 3 3 5 2.410E8 4.36 8.85 2 2 174.50 11.15 3 3 305 33.9 4.83 HVO_2918 thymidylate synthase 11.14 1 2 2 6 8.590E7 2.18 11.14 2 3 239.06 11.14 2 3 332 37.5 4.61 HVO_0122 phosphoglycerate dehydrogenase 11.11 1 3 3 7 1.616E8 6.10 6.17 2 3 309.23 11.11 3 4 324 35.3 5.35 HVO_0837 probable NAD kinase (inorganic polyphosphate/ATP NAD kinase) 11.11 1 2 2 4 1.699E7 2.12 11.11 2 2 157.35 11.11 2 2 243 24.8 4.48 HVO_0469 AstE family protein 11.01 1 3 3 8 1.647E8 4.13 11.01 3 4 356.13 11.01 3 4 318 33.9 5.85 HVO_0397 homolog to aminomethyltransferase (homolog to glycine cleavage system protein T) 10.96 1 3 3 12 1.930E8 1.79 10.96 3 6 425.04 10.96 3 6 365 39.0 4.61 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 10.94 1 2 2 6 1.504E8 6.33 10.94 2 3 267.06 10.94 2 3 265 29.3 4.92 HVO_2383 DNA repair and recombination protein RadB 10.92 1 2 2 3 5.471E7 2.79 10.92 2 3 229 24.6 5.02 HVO_1503 3-isopropylmalate dehydratase small subunit 10.89 1 2 2 10 2.388E8 6.39 10.89 2 5 310.03 10.89 2 5 202 22.0 4.15 HVO_2536 CHP00300 family protein 10.82 1 2 2 9 3.500E8 0.00 10.82 2 4 273.60 10.82 2 5 416 44.8 4.51 HVO_1453 glutamate dehydrogenase (NADP) 10.79 1 4 4 12 2.581E8 3.86 10.79 4 6 538.64 10.79 4 6 417 45.7 4.49 HVO_0733 transcription initiation factor TFB 10.74 1 0 4 14 6.192E8 8.59 10.74 4 7 922.91 10.74 4 7 326 37.2 6.00 HVO_0321 peptide chain release factor aRF-1 10.63 1 4 4 14 2.759E8 7.76 8.45 3 6 658.97 10.63 4 8 414 46.6 4.83 HVO_2600 methionyl aminopeptidase 10.47 1 3 3 9 1.381E8 6.72 6.42 2 4 433.41 10.47 3 5 296 32.3 4.41 HVO_C0054 hypothetical protein 10.47 1 2 2 3 2.756E7 244.56 10.47 2 3 344 37.5 4.70 HVO_1337 rpa-associated protein 10.43 1 5 5 16 3.155E8 5.62 10.43 5 8 702.58 10.43 5 8 623 64.8 3.68 HVO_B0059 cobalt-precorrin 5A hydrolase 10.43 1 3 3 10 1.020E8 8.26 10.43 3 5 427.45 10.43 3 5 326 34.5 4.51 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 10.42 1 0 5 34 9.078E8 29.53 10.42 5 17 2257.85 10.42 5 17 384 42.4 5.40 HVO_1139 squalene synthase 10.34 1 2 2 5 6.135E7 1.83 10.34 2 2 280.86 10.34 2 3 358 39.7 4.54 HVO_2168 AAA-type ATPase (MoxR subfamily) 10.33 1 2 2 10 1.042E8 3.52 10.33 2 5 259.33 10.33 2 5 329 35.9 4.54 HVO_2793 conserved hypothetical protein 10.32 1 2 2 2 5.222E7 2.20 10.32 2 2 252 27.1 4.46 HVO_0048 argininosuccinate lyase 10.25 1 3 3 8 1.295E8 7.05 10.25 3 4 441.33 10.25 3 4 488 50.8 4.53 HVO_1899 DNA-directed RNA polymerase subunit E 10.00 1 2 2 6 1.318E8 0.00 10.00 2 3 229.31 10.00 2 3 190 21.0 4.74 HVO_1327 AAA-type ATPase (CDC48 subfamily) 9.92 1 3 4 11 2.165E8 5.89 6.39 3 5 449.80 9.92 4 6 736 78.1 4.88 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 9.92 1 2 2 10 3.476E8 4.84 9.92 2 5 414.16 9.92 2 5 363 39.7 4.25 HVO_B0371 aldehyde dehydrogenase 9.88 1 3 3 10 7.460E7 7.84 9.88 3 5 461.84 9.88 3 5 496 52.5 4.39 HVO_2761 mevalonate kinase 9.81 1 2 2 2 4.426E7 4.12 9.81 2 2 367 38.2 4.31 HVO_1323 "shikimate kinase, archaeal-type" 9.69 1 2 2 12 3.731E8 11.74 9.69 2 6 822.25 9.69 2 6 289 29.5 4.30 4557890 keratin 5 [Homo sapiens] 9.66 1 0 7 39 9.078E8 28.61 9.66 7 20 2343.94 9.66 7 19 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 9.66 1 0 7 39 9.078E8 28.61 9.66 7 20 2343.94 9.66 7 19 590 62.4 8.06 HVO_1676 transcription initiation factor TFB 9.64 1 0 2 8 2.987E8 6.09 9.64 2 4 377.75 9.64 2 4 332 37.3 5.49 HVO_0100 NMD3 family protein 9.60 1 3 3 7 6.830E7 0.00 9.60 3 4 139.33 6.40 2 3 375 41.6 4.46 HVO_1557 phosphoribosylformylglycinamidine cyclo-ligase 9.57 1 2 2 8 1.969E8 7.57 9.57 2 4 549.15 9.57 2 4 324 33.6 3.99 HVO_2643 NADPH:quinone reductase 9.54 1 2 2 9 4.600E7 8.32 9.54 2 5 321.08 9.54 2 4 346 37.2 4.55 HVO_2160 conserved hypothetical protein 9.53 1 13 13 104 2.033E9 130.63 9.53 13 54 8352.14 9.53 13 50 2257 232.7 3.92 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 9.51 1 0 5 32 1.495E9 14.41 9.51 5 16 1969.44 9.51 5 16 473 51.2 5.05 HVO_1875 O-acetyltransferase (homolog to galactoside O-acetyltransferase) 9.51 1 2 2 4 1.264E8 0.00 9.51 2 2 128.04 9.51 2 2 305 34.1 4.91 HVO_0322 MinD/ParA domain protein 9.47 1 3 3 11 1.856E8 2.96 9.47 3 6 396.48 8.09 2 5 581 58.8 3.70 HVO_0467 PhoU/TrkA-C domain protein 9.45 1 4 4 12 1.864E8 9.38 9.45 4 6 664.63 9.45 4 6 402 43.3 4.49 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 9.43 1 3 3 9 1.072E8 9.45 9.43 3 5 499.63 9.43 3 4 297 32.3 3.98 HVO_B0200 malate synthase 9.40 1 2 2 4 8.946E8 2.79 9.40 2 4 436 48.3 4.30 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 9.39 1 2 2 10 1.420E8 7.76 9.39 2 5 555.27 9.39 2 5 277 30.6 4.30 HVO_1804 nicotinate phosphoribosyltransferase 9.28 1 3 3 11 2.025E8 3.98 9.28 3 5 411.38 9.28 3 6 388 41.1 4.60 HVO_B0001 Orc1-type DNA replication protein 9.27 1 2 2 2 1.666E8 51.60 9.27 2 2 410 45.8 5.33 HVO_C0042 helicase domain protein 9.18 1 9 9 22 2.337E8 9.47 9.18 9 12 924.32 7.93 8 10 1274 144.4 4.67 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 9.12 1 4 4 9 1.017E8 4.87 9.12 4 4 400.82 9.12 4 5 658 72.1 4.70 HVO_2256 DUF262 family protein 9.09 1 4 4 22 2.797E8 14.51 9.09 4 11 1388.62 9.09 4 11 462 54.9 4.89 HVO_2183 aldehyde ferredoxin oxidoreductase 9.02 1 5 5 7 5.561E7 3.62 6.38 3 3 358.82 6.84 4 4 643 69.3 4.59 21961227 Keratin 6B [Homo sapiens] 8.87 1 0 6 51 1.284E9 44.11 8.87 6 26 3252.43 8.87 6 25 564 60.0 8.00 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 8.80 1 0 4 14 1.221E9 7.47 8.80 4 7 891.18 8.80 4 7 432 48.1 5.02 HVO_2951 tryptophan--tRNA ligase 8.70 1 3 3 5 1.397E8 1.85 8.70 3 3 97.45 4.91 2 2 529 59.1 4.53 HVO_1698 CBS/parB domain protein 8.68 1 1 2 3 1.019E9 0.00 8.68 2 3 265 29.4 4.92 HVO_B0115 fumarylacetoacetase family protein 8.48 1 2 2 8 3.205E8 4.70 8.48 2 4 451.71 8.48 2 4 283 30.3 4.21 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 8.36 1 3 3 16 5.210E8 4.96 6.69 2 7 766.34 8.36 3 9 299 32.0 4.53 HVO_1235 creatininase 8.33 1 2 2 4 3.755E7 1.87 8.33 2 2 126.32 8.33 2 2 264 29.2 4.84 HVO_2707 GFO family oxidoreductase 8.33 1 3 3 7 1.501E8 4.10 5.91 2 3 411.39 8.33 3 4 372 41.0 4.55 HVO_1058 TrkA domain protein 8.31 1 3 3 11 2.735E8 5.88 8.31 3 6 432.09 6.07 2 5 445 47.7 4.35 HVO_2153 probable copper-containing oxidoreductase 8.31 1 2 2 9 1.671E8 10.65 8.31 2 4 491.03 8.31 2 5 385 42.1 5.82 HVO_2193 phosphoribosylaminoimidazole-succinocarboxamide synthase 8.26 1 2 2 6 7.071E7 4.18 8.26 2 3 317.74 8.26 2 3 339 38.1 4.50 HVO_B0038A D-xylonate dehydratase 8.25 1 1 3 11 3.542E8 4.06 8.25 3 5 487.69 8.25 3 6 412 45.5 4.55 HVO_0968 NADH dehydrogenase-like complex subunit CD 8.16 1 0 4 11 4.907E8 8.40 6.56 3 5 708.34 8.16 4 6 564 63.3 4.60 HVO_2923 proteasome alpha subunit 8.03 1 1 2 6 6.983E8 2.05 8.03 2 3 387.90 8.03 2 3 249 26.7 4.39 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 8.02 1 2 2 7 5.805E7 6.40 8.02 2 3 512.89 8.02 2 4 349 37.0 4.70 HVO_1957 proteasome-activating nucleotidase 8.01 1 2 2 2 1.372E8 212.16 8.01 2 2 412 45.6 4.48 HVO_0658 tRNA pseudouridine(13) synthase TruD 7.99 1 2 2 6 8.122E7 1.62 7.99 2 3 101.44 7.99 2 3 463 50.6 4.70 HVO_A0485 aminotransferase class V 7.98 1 2 2 6 1.802E8 5.79 7.98 2 3 386.59 7.98 2 3 351 37.3 4.26 HVO_1914 acetyl-CoA C-acyltransferase 7.96 1 2 2 8 2.486E7 1.65 7.96 2 4 293.51 7.96 2 4 377 39.9 4.41 HVO_0853 DNA double-strand break repair protein Mre11 7.94 1 2 2 4 5.302E7 1.75 7.94 2 2 139.79 7.94 2 2 441 48.1 4.39 HVO_A0452 UspA domain protein 7.85 1 2 2 4 4.486E7 0.00 7.85 2 2 81.25 7.85 2 2 293 31.3 4.63 HVO_1711 glucoamylase 7.81 1 9 9 24 1.881E8 11.91 7.81 9 13 1091.41 7.02 8 11 1511 166.1 4.64 HVO_2416 TatD-related deoxyribonuclease 7.80 1 2 2 2 1.038E7 155.58 7.80 2 2 282 30.8 4.75 HVO_2227 siroheme decarboxylase AhbA 7.78 1 2 2 4 7.668E7 0.00 7.78 2 2 108.99 7.78 2 2 347 39.1 4.69 HVO_0854 DNA double-strand break repair ATPase Rad50 7.73 1 5 5 9 5.803E7 3.53 4.26 4 4 343.34 7.73 5 5 893 100.0 4.58 HVO_1356 sensor box histidine kinase 7.64 1 2 2 7 1.775E8 6.14 7.64 2 3 394.16 7.64 2 4 550 61.1 4.60 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 7.52 1 3 3 5 1.210E8 1.93 4.47 2 2 248.71 7.52 3 3 492 52.1 4.83 HVO_2428 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 7.37 1 3 3 8 1.512E8 3.66 7.37 3 4 374.70 7.37 3 4 353 36.7 4.65 HVO_1979 tRNA pseudouridine synthase Pus10 7.26 1 3 3 10 7.802E8 7.64 7.26 3 5 738.33 7.26 3 5 427 46.9 4.39 HVO_1668 gamma-glutamylcysteine synthetase 7.26 1 2 2 2 0.000E0 74.02 7.26 2 2 358 39.9 4.72 HVO_1895 KEOPS complex subunit Kae1/Bud32 7.25 1 2 2 9 1.175E8 9.22 7.25 2 4 511.27 7.25 2 5 552 59.0 5.07 HVO_1308 3-phosphoshikimate 1-carboxyvinyltransferase 7.21 1 3 3 19 2.953E8 3.13 7.21 3 9 671.45 7.21 3 10 430 44.2 4.37 HVO_C0044 PLD domain protein 7.21 1 2 2 2 6.472E7 0.00 7.21 2 2 333 36.4 4.94 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 7.12 1 2 2 5 1.335E8 1.82 7.12 2 2 200.61 7.12 2 3 337 35.9 4.69 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 7.09 1 0 5 34 9.078E8 29.53 7.09 5 17 2257.85 7.09 5 17 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 7.09 1 0 5 34 9.078E8 29.53 7.09 5 17 2257.85 7.09 5 17 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 7.09 1 0 5 34 9.078E8 29.53 7.09 5 17 2257.85 7.09 5 17 564 60.2 8.00 84040267 Keratin 6 isoform K6e [Homo sapiens] 7.09 1 0 5 34 9.078E8 29.53 7.09 5 17 2257.85 7.09 5 17 564 60.0 7.72 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 7.09 1 2 2 2 5.577E7 1.78 7.09 2 2 395 42.4 4.54 HVO_0551 DNA mismatch repair protein MutL 7.07 1 4 4 12 1.193E8 6.87 7.07 4 5 541.54 7.07 4 7 735 78.7 4.50 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 7.00 1 2 2 4 2.605E7 1.95 7.00 2 2 160.48 7.00 2 2 400 44.2 4.32 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 6.96 1 3 3 7 1.564E8 4.18 6.96 3 4 204.15 3.78 2 3 661 71.0 4.35 HVO_1113 "FtsZ family protein, type III" 6.94 1 0 3 9 8.363E8 2.44 5.40 2 4 470.97 6.94 3 5 389 40.8 4.89 HVO_0818 threonine synthase 6.94 1 2 2 7 4.370E8 710.76 6.94 2 7 389 40.8 4.31 HVO_0552 DNA mismatch repair protein MutS 6.93 1 5 5 20 2.860E8 6.47 6.93 5 10 930.79 6.93 5 10 924 99.2 4.65 HVO_1129 conserved hypothetical protein 6.92 1 2 2 3 1.764E8 194.64 6.92 2 3 390 43.0 4.44 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 6.86 1 4 4 12 4.654E8 10.18 6.86 4 6 653.19 6.86 4 6 612 67.3 4.16 HVO_2333 conserved hypothetical protein 6.82 1 3 3 8 1.364E8 2.00 6.82 3 4 296.05 6.82 3 4 308 34.9 4.54 HVO_1578 probable NADH dehydrogenase 6.80 1 2 2 6 4.794E7 7.09 6.80 2 3 427.97 6.80 2 3 397 42.8 4.40 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 6.80 1 4 4 12 1.423E8 4.30 6.80 4 6 627.72 6.80 4 6 706 73.3 4.39 HVO_0326 CTP-dependent riboflavin kinase 6.75 1 2 2 6 2.407E7 3.48 6.75 2 3 171.90 6.75 2 3 237 25.9 4.55 HVO_0464 threonine ammonia-lyase 6.70 1 2 2 6 4.297E7 0.00 6.70 2 3 216.19 6.70 2 3 403 43.7 4.72 HVO_A0618 flavin-dependent pyridine nucleotide oxidoreductase (homolog to coenzyme A disulfide reductase) 6.53 1 2 2 5 2.666E7 1.99 6.53 2 3 202.68 6.53 2 2 475 49.3 4.49 HVO_2350 YyaL family protein 6.52 1 2 2 6 9.115E7 4.53 6.52 2 3 327.85 6.52 2 3 552 58.8 4.59 HVO_1079 sulfate adenylyltransferase small subunit 6.46 1 2 2 4 1.055E7 0.00 6.46 2 2 142.44 6.46 2 2 325 37.5 4.18 HVO_0868 NAD-dependent epimerase/dehydratase 6.38 1 2 2 4 2.764E8 0.00 6.38 2 4 329 36.1 4.55 HVO_0662 HTH domain protein / thiamine-phosphate synthase 6.35 1 2 2 6 3.198E7 4.34 6.35 2 3 240.92 6.35 2 3 299 31.9 4.44 HVO_1967 glucose-6-phosphate isomerase 6.28 1 2 2 8 1.836E8 8.77 6.28 2 4 540.57 6.28 2 4 430 45.6 4.40 HVO_0220 ATP-dependent DNA helicase MCM 6.27 1 5 5 14 1.161E8 8.29 6.27 5 7 615.48 6.27 5 7 702 78.8 4.73 HVO_1357 receiver/bat box HTH-10 family transcription regulator 6.19 1 3 3 5 5.394E7 0.00 6.19 3 3 110.16 2.92 2 2 582 62.7 4.40 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 6.19 1 2 2 6 8.200E7 0.00 6.19 2 3 122.14 6.19 2 3 420 45.0 4.86 HVO_A0156 acyl-CoA synthetase 6.17 1 0 3 7 1.822E8 2.13 3.92 2 3 322.73 6.17 3 4 664 74.0 4.40 HVO_A0328 2-keto-3-deoxygluconate kinase 5.97 1 1 2 4 1.559E8 2.03 5.97 2 2 181.04 5.97 2 2 318 34.0 4.60 HVO_B0256 aldehyde ferredoxin oxidoreductase 5.95 1 3 3 8 8.527E7 6.34 5.95 3 4 266.04 5.95 3 4 555 59.9 4.55 HVO_0521 "tRNA adenylyltransferase, CCA-adding" 5.88 1 2 2 4 1.254E8 2.07 5.88 2 2 215.25 5.88 2 2 459 50.5 4.63 HVO_2639 DUF1611 family protein 5.87 1 2 2 6 1.306E7 1.85 5.87 2 3 276.72 5.87 2 3 341 36.3 4.44 HVO_1629 conserved hypothetical protein 5.65 1 2 2 2 1.694E8 0.00 5.65 2 2 531 56.3 4.69 HVO_1723 DNA repair helicase Rad25 5.61 1 3 3 8 4.329E7 7.94 3.88 2 4 386.25 5.61 3 4 695 76.8 4.69 HVO_1375 O-succinylbenzoic acid--CoA ligase 5.54 1 2 2 7 6.121E7 6.18 5.54 2 3 290.35 5.54 2 4 614 64.7 4.28 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 5.48 1 0 3 12 1.221E9 4.22 5.48 3 6 692.65 5.48 3 6 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 5.48 1 0 3 12 1.221E9 4.22 5.48 3 6 692.65 5.48 3 6 456 49.2 4.77 HVO_1710 alpha amylase 5.47 1 4 4 13 1.143E8 4.46 3.99 3 7 501.02 5.47 4 6 677 75.0 4.45 HVO_2158 malic enzyme (NADP) 5.46 1 0 2 6 2.190E8 4.93 5.46 2 3 423.17 5.46 2 3 751 81.4 4.55 31559823 keratin 25D [Homo sapiens] 5.39 1 0 3 24 1.192E9 11.96 5.39 3 12 1496.31 5.39 3 12 464 50.6 5.47 HVO_0639 AAA-type ATPase (MoxR subfamily) 5.38 1 2 2 6 7.120E7 3.58 5.38 2 3 259.55 5.38 2 3 316 34.7 4.89 386849 keratin type II 5.33 1 0 3 12 5.875E8 12.27 5.33 3 6 920.42 5.33 3 6 563 59.9 7.94 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 5.28 1 2 2 4 1.128E8 2.40 5.28 2 2 217.85 5.28 2 2 398 43.4 4.37 HVO_2908 dihydropteroate synthase 5.28 1 2 2 3 3.752E7 227.84 5.28 2 3 379 40.8 4.53 4504911 keratin 13 isoform b [Homo sapiens] 5.24 1 0 2 8 3.904E8 6.60 5.24 2 4 474.69 5.24 2 4 420 45.8 4.88 HVO_A0257 Orc1-type DNA replication protein 4.94 1 2 2 7 2.699E7 1.71 4.94 2 3 188.99 4.94 2 4 425 48.0 4.94 HVO_2321 bacterial-type DNA primase DnaG 4.87 1 2 2 2 2.834E7 157.93 4.87 2 2 472 49.4 4.36 HVO_1867 lysine--tRNA ligase 4.86 1 3 3 14 2.289E8 6.26 4.86 3 7 591.98 4.86 3 7 555 62.1 4.46 6016411 "Keratin, type I cytoskeletal 13 (Cytokeratin-13) (CK-13) (Keratin-13) (K13)" 4.80 1 0 2 8 3.904E8 6.60 4.80 2 4 474.69 4.80 2 4 458 49.6 4.96 27894337 keratin 20 [Homo sapiens] 4.72 1 1 2 6 1.061E8 4.22 4.72 2 3 332.93 4.72 2 3 424 48.5 5.69 HVO_2271 type I site-specific deoxyribonuclease subunit RmeS 4.63 1 2 2 5 3.750E7 1.90 4.63 2 2 166.80 4.63 2 3 410 46.0 4.89 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 4.56 1 2 2 5 7.508E7 311.70 4.56 2 5 482 50.6 4.31 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 4.30 1 2 2 8 1.716E8 3.06 4.30 2 4 275.48 4.30 2 4 838 89.1 4.65 HVO_2004 serine O-acetyltransferase 4.18 1 1 2 9 6.279E8 0.00 4.18 2 5 294.79 4.18 2 4 287 31.9 5.21 HVO_B0154 receiver/sensor box histidine kinase 4.15 1 5 5 11 1.006E8 1.83 4.15 5 6 402.17 3.31 4 5 1301 144.1 4.39 HVO_0069 sulfatase 4.08 1 1 2 2 7.603E7 147.64 4.08 2 2 515 57.4 4.35 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 4.05 1 1 2 3 9.820E8 1.80 4.05 2 3 444 47.1 4.77 31559829 keratin 25A [Homo sapiens] 4.00 1 0 2 20 9.035E8 11.96 4.00 2 10 1314.22 4.00 2 10 450 49.3 5.08 HVO_2888 homolog to elongator complex protein ELP3 4.00 1 2 2 6 2.620E7 3.94 4.00 2 3 180.55 4.00 2 3 550 62.6 5.01 31074633 keratin 6L [Homo sapiens] 3.93 1 0 2 8 9.363E8 7.94 3.93 2 4 709.42 3.93 2 4 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 3.93 1 0 2 8 9.363E8 7.94 3.93 2 4 709.42 3.93 2 4 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 3.93 1 0 2 8 9.363E8 7.94 3.93 2 4 709.42 3.93 2 4 535 57.7 7.20 31559819 keratin 25C [Homo sapiens] 3.92 1 0 2 20 9.035E8 11.96 3.92 2 10 1314.22 3.92 2 10 459 49.8 5.14 HVO_0029 UvrABC system protein B 3.87 1 2 2 3 2.163E7 0.00 3.87 2 3 698 79.0 4.45 HVO_3000 DNA ligase (NAD) 3.86 1 2 2 6 6.314E8 4.44 3.86 2 3 365.68 3.86 2 3 699 75.8 4.50 HVO_2269 type I site-specific deoxyribonuclease subunit RmeR 3.78 1 2 2 3 5.014E7 4.20 3.78 2 3 740 85.6 4.70 HVO_1354 DNA mismatch repair protein MutS 3.62 1 2 2 6 3.227E7 0.00 3.62 2 3 251.51 3.62 2 3 580 62.1 4.56 HVO_0014 ATP-dependent DNA helicase Hel308a 3.51 1 2 2 6 1.357E8 0.00 3.51 2 3 241.96 3.51 2 3 827 90.3 4.67 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 3.50 1 0 2 8 1.788E9 0.00 3.50 2 4 389.72 3.50 2 4 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 3.50 1 0 2 8 1.788E9 0.00 3.50 2 4 389.72 3.50 2 4 400 44.1 5.14 31074631 keratin 1b [Homo sapiens] 3.46 1 0 2 22 2.409E9 21.72 3.46 2 11 1451.11 3.46 2 11 578 61.8 5.97 4504919 keratin 8 [Homo sapiens] 3.31 1 0 3 24 3.456E8 17.26 3.31 3 12 1408.34 3.31 3 12 483 53.7 5.59 HVO_1656 YyaL family protein 2.99 1 2 2 2 2.817E7 122.91 2.99 2 2 703 77.3 4.49 HVO_2955 DEAD/DEAH box helicase 2.18 1 2 2 4 4.282E7 0.00 2.18 2 2 114.56 2.18 2 2 779 85.8 4.94 HVO_0858 DNA-directed DNA polymerase B (intein-containing) 1.35 1 2 2 4 3.048E7 2.13 1.35 2 2 156.23 1.35 2 2 1335 150.5 4.60 HVO_0689 chromosome segregation protein Smc 1.13 1 2 2 4 1.526E8 352.37 1.13 2 4 1240 138.1 4.39