Accession Description ?Coverage ?# Proteins ?# Unique Peptides ?# Peptides ?# PSMs Area Score A2 Coverage A2 # Peptides A2 # PSM A2 Score A4 Coverage A4 # Peptides A4 # PSM A4 # AAs MW [kDa] calc. pI HVO_2757 50S ribosomal protein L1 92.45 1 18 18 1298 3.051E9 2020.18 87.74 17 644 90333.42 92.45 18 654 212 23.1 4.42 HVO_1507 acetolactate synthase small subunit 90.83 1 15 15 227 1.295E8 249.05 90.83 15 113 13258.73 82.11 14 114 218 23.7 4.94 HVO_2548 50S ribosomal protein L6 90.45 1 11 11 700 7.853E8 1045.50 89.33 10 342 46914.32 90.45 11 358 178 19.6 4.68 HVO_2564 50S ribosomal protein L3 84.62 1 22 23 1694 4.851E9 1967.14 83.14 22 861 92710.21 83.14 22 833 338 37.2 6.68 HVO_0481 glyceraldehyde-3-phosphate dehydrogenase (NAD) (phosphorylating) 81.43 1 19 19 607 5.928E8 719.34 63.14 17 302 32946.30 81.43 19 305 350 37.6 4.54 HVO_0133 thermosome subunit 1 80.89 1 32 34 6123 4.837E9 9101.07 80.89 34 3041 411365.13 80.89 34 3082 560 58.9 4.25 HVO_2779 50S ribosomal protein L18e 80.17 1 9 9 171 3.117E8 288.39 80.17 9 86 11947.09 80.17 9 85 116 12.7 8.50 HVO_0725 probable oxidoreductase (short-chain dehydrogenase family) 78.29 1 17 17 362 6.122E8 550.52 78.29 17 181 25936.89 78.29 17 181 281 30.2 4.78 HVO_2545 50S ribosomal protein L18 77.72 1 7 7 503 7.742E8 607.72 77.72 7 251 29226.06 77.72 7 252 184 20.2 5.60 HVO_0329 branched-chain amino acid aminotransferase 77.24 1 21 21 546 5.546E8 775.21 77.24 21 273 37162.87 77.24 21 273 312 35.0 4.58 HVO_0359 translation elongation factor aEF-1 alpha subunit 77.20 1 18 21 713 1.953E9 930.31 72.92 20 336 46868.32 74.35 20 377 421 45.7 4.73 HVO_1145 30S ribosomal protein S1e 76.82 1 14 15 990 1.843E9 1319.36 75.00 14 496 51558.35 76.82 15 494 220 24.8 4.86 HVO_A0207 CRISPR-associated protein Cas7 75.00 1 16 16 434 8.751E8 597.91 75.00 15 218 25210.71 75.00 16 216 340 38.2 4.54 HVO_1009 probable oxidoreductase (aldo-keto reductase family protein) 74.71 1 21 21 376 7.285E8 536.69 71.47 19 188 25033.59 74.71 21 188 340 38.8 4.58 HVO_0455 thermosome subunit 2 74.69 1 36 37 4057 4.401E9 6659.38 73.61 35 2073 298614.65 74.69 37 1984 557 59.3 4.37 HVO_2563 50S ribosomal protein L4 74.60 1 13 14 613 1.184E9 767.33 74.60 14 299 33925.20 74.60 14 314 248 27.0 6.44 HVO_2542 50S ribosomal protein L15 73.94 1 9 9 270 4.500E8 369.15 73.94 9 135 17545.20 73.94 9 135 165 17.8 4.93 HVO_0239 glutamine synthetase 73.68 1 27 28 2112 6.762E9 3084.99 67.32 26 1041 145125.75 67.54 26 1071 456 50.5 4.56 HVO_0778 thermosome subunit 3 73.28 1 31 34 2370 4.107E9 4035.88 73.28 34 1185 190366.42 73.28 34 1185 524 55.2 4.59 HVO_2336 pyridoxal biosynthesis lyase PdxS 72.85 1 18 18 472 6.561E8 648.92 69.54 16 229 32884.13 72.85 18 243 302 32.5 4.81 HVO_2380 AAA-type ATPase (CDC48 subfamily) 72.14 1 46 47 727 7.299E8 912.07 72.14 47 366 41998.64 72.14 47 361 743 81.9 4.82 HVO_2636 PspA domain protein 71.74 1 16 16 283 1.843E8 365.69 71.74 16 140 17097.29 69.93 15 143 276 30.9 4.61 HVO_2559 50S ribosomal protein L22 68.63 1 7 8 52 4.343E7 60.05 43.14 5 23 3754.47 68.63 8 29 153 16.9 5.60 HVO_2425 GNAT family acetyltransferase 68.52 1 12 12 113 1.078E8 138.26 68.52 12 57 6410.55 63.89 11 56 216 24.4 4.54 HVO_2547 50S ribosomal protein L32e 67.66 1 16 16 666 2.694E9 933.81 60.43 15 319 43493.38 61.70 14 347 235 25.8 4.75 HVO_2486 propionyl-CoA carboxylase biotin carboxylase component 66.44 1 32 33 635 5.445E8 979.16 66.44 33 321 42393.73 63.77 32 314 599 65.3 4.51 HVO_1189 aldehyde dehydrogenase 65.94 1 26 26 720 5.981E8 654.78 58.66 25 347 34223.29 65.94 26 373 508 56.1 4.59 HVO_0081 "glutamate-1-semialdehyde 2,1-aminomutase" 65.62 1 18 18 209 3.047E8 271.61 65.62 18 103 12493.65 60.00 17 106 445 47.8 4.86 HVO_0356 translation elongation factor aEF-2 65.34 1 35 35 738 6.621E8 1000.65 65.34 35 366 44241.54 65.34 35 372 727 80.4 4.73 HVO_1305 pyruvate--ferredoxin oxidoreductase alpha subunit 65.29 1 25 25 1090 3.788E9 1351.50 64.03 24 536 64955.03 62.12 24 554 631 68.4 4.49 HVO_2724 beta-lactamase domain protein 64.89 1 23 23 745 9.046E8 659.77 64.89 23 367 35474.25 64.89 23 378 450 50.1 5.40 HVO_2900 fumarate hydratase 64.82 1 22 22 507 6.704E8 700.43 63.97 21 254 29928.08 64.82 22 253 469 50.1 4.78 HVO_1539 glycerol-3-phosphate dehydrogenase subunit B 64.22 1 17 17 226 1.539E8 282.06 62.80 16 112 12684.42 64.22 17 114 422 43.6 4.72 HVO_2562 50S ribosomal protein L23 63.86 1 5 5 59 9.438E7 100.62 50.60 4 28 5493.22 63.86 5 31 83 9.4 5.48 HVO_1506 ketol-acid reductoisomerase 63.79 1 14 14 970 9.522E8 1131.27 57.76 12 441 61298.80 63.79 14 529 348 37.9 4.34 HVO_0805 conserved hypothetical protein 63.41 1 2 2 2 6.947E6 2.19 63.41 2 2 82 8.7 3.83 HVO_0790 "2-amino-3,7-dideoxy-D-threo-hept-6-ulosonate synthase" 63.16 1 12 12 223 3.754E8 311.96 63.16 12 113 14157.12 63.16 12 110 266 27.8 4.84 HVO_0812 phosphoenolpyruvate synthase 62.94 1 44 44 991 1.751E9 1157.68 61.76 41 490 58425.43 60.32 43 501 761 83.1 4.63 HVO_0478 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)) (phosphorylating) 62.54 1 14 14 178 1.911E8 190.50 62.54 14 90 8560.37 57.75 13 88 355 38.2 4.68 HVO_1304 pyruvate--ferredoxin oxidoreductase beta subunit 62.18 1 12 12 758 2.360E9 871.77 62.18 12 389 42028.06 62.18 12 369 312 34.5 4.98 HVO_0801 stomatin family protein 62.03 1 25 31 599 9.899E8 881.50 62.03 31 303 41159.76 62.03 31 296 424 46.4 4.37 HVO_0677 aspartate--tRNA ligase 61.52 1 18 18 492 3.210E8 600.39 61.52 18 246 26672.68 61.52 18 246 434 48.7 4.50 HVO_2465 succinate--CoA ligase (ADP-forming) beta subunit 60.89 1 17 17 269 6.004E8 352.63 59.32 16 134 16024.33 60.89 16 135 381 41.0 4.23 HVO_1401 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 60.48 1 14 14 1045 3.068E9 1526.89 60.48 14 524 57842.32 60.48 14 521 377 39.2 4.18 HVO_0980 NADH dehydrogenase-like complex subunit CD 60.32 1 22 29 978 2.669E9 1132.17 56.91 28 489 61084.40 60.32 29 489 557 63.4 4.53 HVO_2862 serine hydroxymethyltransferase 60.24 1 15 15 284 5.872E8 364.65 60.24 15 143 19027.03 60.24 15 141 415 44.3 4.53 HVO_0484 50S ribosomal protein L10e 60.23 1 13 14 232 1.208E9 240.74 51.14 12 111 14005.81 57.39 13 121 176 19.8 8.72 HVO_2815 3-hydroxyacyl-CoA dehydrogenase / enoyl-CoA hydratase 60.21 1 25 25 373 5.279E8 516.96 60.21 25 189 21489.03 54.92 23 184 661 71.0 4.35 HVO_2756 50S ribosomal protein L10 60.06 1 14 14 794 1.783E9 1242.82 60.06 14 397 47252.34 60.06 14 397 348 36.9 3.99 HVO_1091 proteasome alpha subunit 59.92 1 14 15 390 1.822E9 525.78 59.92 15 196 24646.43 59.92 15 194 252 27.6 4.56 HVO_0314 A-type ATP synthase subunit C 59.77 1 19 19 312 1.875E8 427.69 55.75 18 150 22510.52 59.77 19 162 348 38.7 4.50 HVO_0887 oxoglutarate--ferredoxin oxidoreductase beta subunit 59.23 1 10 10 436 1.863E9 554.62 59.23 10 219 27582.44 59.23 10 217 287 31.0 4.73 HVO_2401 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 59.20 1 15 15 169 2.039E8 197.75 59.20 15 84 8605.98 45.24 13 85 473 50.8 4.58 HVO_2759 peptidase M42 family protein 59.04 1 14 14 173 2.757E8 256.78 59.04 14 87 10669.41 59.04 14 86 354 37.0 4.40 HVO_B0198 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 58.79 1 16 17 750 1.359E9 1015.44 58.79 17 369 41292.00 58.79 17 381 398 43.4 4.37 HVO_1488 D-gluconate dehydratase 58.74 1 16 19 422 1.038E9 541.58 57.52 18 209 23358.44 58.74 19 213 412 45.8 4.60 HVO_0317 A-type ATP synthase subunit B 58.55 1 19 21 585 1.915E9 834.61 58.55 21 295 35903.50 57.91 20 290 468 51.9 4.25 HVO_0973 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 57.81 1 16 16 165 2.044E8 198.18 55.99 15 82 9537.77 57.81 16 83 384 41.4 4.41 HVO_2620 cytochrome bc1 complex Rieske iron-sulfur protein 57.65 1 8 8 233 7.033E8 332.97 55.87 7 116 13559.17 57.65 8 117 281 30.2 4.31 HVO_2554 50S ribosomal protein L14 57.58 1 9 9 167 4.036E8 208.36 47.73 8 85 9477.70 57.58 9 82 132 14.2 9.76 HVO_1273 inosine-5'-monophosphate dehydrogenase 56.43 1 20 20 593 3.863E8 685.77 53.82 19 295 30971.67 56.43 20 298 498 53.3 4.55 HVO_1858 30S ribosomal protein S19e 56.29 1 5 5 53 3.007E7 38.30 44.37 4 20 3486.18 47.68 4 33 151 16.7 4.84 HVO_1454 aspartate carbamoyltransferase catalytic subunit 56.25 1 10 10 139 6.840E7 174.32 56.25 10 70 8390.53 56.25 10 69 304 33.7 4.92 HVO_2046 sulfatase domain protein 56.05 1 16 16 183 1.523E8 234.70 56.05 16 91 10064.68 56.05 16 92 405 45.5 4.87 HVO_0536 ferritin 55.11 1 5 5 50 6.985E7 75.12 55.11 5 25 1964.07 55.11 5 25 176 19.9 4.50 HVO_B0376 probable oxidoreductase (aldo-keto reductase family protein) 55.06 1 20 20 314 2.720E8 356.18 55.06 20 156 16677.88 55.06 20 158 336 38.0 4.61 HVO_2808 succinate dehydrogenase subunit A (flavoprotein) 54.96 1 23 24 583 6.915E8 642.80 54.96 24 296 30504.50 53.98 23 287 615 67.6 4.88 HVO_2889 RecJ domain protein 54.87 1 29 29 511 4.545E8 733.69 54.87 29 257 33869.00 54.87 29 254 729 79.1 4.37 HVO_0313 A-type ATP synthase subunit E 54.64 1 9 9 170 7.998E7 192.54 47.42 7 76 10870.46 54.64 9 94 194 22.0 4.31 HVO_2588 isocitrate dehydrogenase (NADP) 54.42 1 19 19 271 3.443E8 296.86 51.31 18 135 14209.40 54.42 19 136 419 45.8 4.59 HVO_A0205 CRISPR-associated endoribonuclease Cas6 54.41 1 10 10 131 9.965E7 157.96 54.41 10 66 6775.39 54.41 10 65 272 31.0 5.44 HVO_0817 phytoene dehydrogenase (phytoene desaturase) 53.41 1 22 23 254 2.183E8 280.55 53.41 23 126 13805.04 53.41 23 128 425 46.1 4.98 HVO_2538 alpha/beta hydrolase fold protein 53.35 1 12 12 205 2.062E8 245.67 53.35 12 101 13301.44 53.35 12 104 313 33.8 6.06 HVO_1894 conserved hypothetical protein 53.26 1 3 3 25 5.160E7 10.43 53.26 3 12 889.18 53.26 3 13 92 10.3 4.67 HVO_0972 DUF1628 family protein 53.18 1 4 4 497 1.207E8 975.89 53.18 4 250 40838.65 53.18 4 247 173 17.7 4.09 HVO_0692 5'-methylthioadenosine phosphorylase MtaP 52.80 1 8 8 54 2.624E7 55.93 41.96 7 25 2515.27 52.80 8 29 286 31.2 4.54 HVO_1578 probable NADH dehydrogenase 52.64 1 19 19 876 1.580E9 1527.90 52.64 19 440 63209.41 52.64 19 436 397 42.8 4.40 HVO_0025 thiosulfate sulfurtransferase 52.10 1 8 8 121 1.912E8 133.21 52.10 8 61 6714.21 52.10 8 60 286 32.1 4.28 HVO_B0132 PQQ repeat protein 51.85 1 11 11 85 6.833E7 113.32 45.93 10 42 4471.11 51.85 11 43 405 41.9 4.64 HVO_0668 2-oxoacid dehydrogenase E1 component beta subunit 51.79 1 9 9 93 1.024E8 106.02 40.18 8 45 4313.01 51.79 9 48 336 36.0 4.51 HVO_1400 ABC-type transport system ATP-binding protein (probable substrate sugar) 51.64 1 18 18 198 1.174E8 230.94 51.64 18 99 10504.69 51.64 18 99 519 56.8 4.68 HVO_1306 chorismate synthase 51.43 1 11 11 184 5.293E7 248.17 51.43 11 91 9492.10 51.43 11 93 385 41.9 4.83 HVO_A0208 "CRISPR-associated endoribonuclease Cas5, Hmari subtype" 51.32 1 11 11 99 1.250E8 163.35 51.32 11 52 7838.29 45.66 9 47 265 29.3 4.92 HVO_0888 oxoglutarate--ferredoxin oxidoreductase alpha subunit 51.19 1 27 27 1039 1.638E9 1455.15 45.90 25 515 70116.67 47.95 25 524 586 64.0 4.49 HVO_0117 translation initiation factor aIF-6 51.13 1 7 7 143 2.850E8 239.58 51.13 7 71 9392.68 51.13 7 72 221 23.0 4.27 HVO_2902 glutamyl-tRNA(Gln) amidotransferase subunit E 51.12 1 24 24 284 2.547E8 370.27 46.15 23 142 16366.78 47.60 23 142 624 67.6 4.27 HVO_1705 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 51.03 1 12 12 447 6.305E8 549.34 51.03 12 221 26016.28 51.03 12 226 388 41.9 4.35 HVO_2774 enolase 50.88 1 12 13 192 9.303E8 202.26 50.88 13 96 10035.21 49.12 12 96 399 42.0 4.37 HVO_0628 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 50.87 1 12 12 2609 2.191E9 4470.56 50.87 12 1307 159914.00 50.87 12 1302 574 62.8 4.17 HVO_2487 aspartate-semialdehyde dehydrogenase 50.87 1 8 8 250 4.659E8 346.11 50.87 8 127 12111.18 50.87 8 123 344 36.6 4.41 HVO_2543 50S ribosomal protein L30 50.65 1 6 6 175 3.530E8 196.67 50.65 6 88 10443.67 50.65 6 87 154 17.1 4.77 HVO_1348 probable YjeF family carbohydrate kinase 50.63 1 19 20 245 3.278E8 367.29 50.63 20 123 17473.84 50.63 20 122 478 48.8 4.45 HVO_0870 proline--tRNA ligase 50.61 1 17 17 121 3.982E7 124.68 48.16 16 62 6585.54 47.75 16 59 488 54.9 4.44 HVO_0806 pyruvate kinase 50.60 1 20 21 279 2.124E8 370.54 50.60 21 140 16275.47 49.91 20 139 585 62.0 4.54 HVO_0349 DNA-directed RNA polymerase subunit A' 50.31 1 39 39 708 4.046E8 965.06 47.34 38 357 46440.21 49.80 38 351 976 108.8 4.81 HVO_2708 YfiH family protein 50.31 1 10 10 176 2.002E8 232.04 50.31 10 87 10197.95 50.31 10 89 322 35.4 4.35 HVO_2506 "isopentenyl-diphosphate delta-isomerase, type I" 50.26 1 7 7 39 1.764E7 33.26 43.39 6 19 1467.81 50.26 6 20 189 21.7 4.46 HVO_2495 DUF106 family protein 50.16 1 9 9 82 1.230E8 107.78 34.75 8 40 4430.06 50.16 9 42 305 33.5 4.58 HVO_2555 30S ribosomal protein S17 50.00 1 4 4 47 3.531E7 63.14 50.00 4 23 2710.61 50.00 4 24 114 12.7 4.81 HVO_2560 30S ribosomal protein S19 50.00 1 5 5 120 5.393E7 112.69 50.00 5 60 6286.34 50.00 5 60 140 16.0 5.57 HVO_2969 threonine synthase 49.64 1 14 14 104 1.316E8 142.87 43.91 13 51 5697.78 49.64 14 53 419 44.4 4.49 HVO_0880 conserved hypothetical protein 49.51 1 14 15 130 5.908E7 141.96 49.51 15 65 6807.50 45.60 14 65 307 36.3 4.74 HVO_0773 probable S-adenosylmethionine-dependent methyltransferase 49.40 1 9 10 57 4.457E7 58.61 49.40 10 28 2734.10 49.40 10 29 251 27.8 6.06 HVO_0979 NADH dehydrogenase-like complex subunit B 49.36 1 10 11 152 4.441E8 179.58 41.20 10 76 8581.88 47.64 10 76 233 26.1 5.01 HVO_2777 30S ribosomal protein S9 49.24 1 7 7 53 3.680E7 66.38 49.24 7 26 2693.26 49.24 7 27 132 14.7 9.74 HVO_1238 probable oxidoreductase (aldo-keto reductase family protein) 49.07 1 14 14 172 8.673E7 233.26 44.44 12 85 11383.54 49.07 14 87 324 36.6 4.68 HVO_1799 geranylgeranyl reductase / dolichol omega-reductase 49.02 1 14 14 226 1.095E8 272.27 42.44 12 106 15083.56 49.02 14 120 410 45.4 4.75 HVO_2153 probable copper-containing oxidoreductase 48.83 1 16 16 288 6.260E8 359.13 48.83 16 146 16900.13 48.83 15 142 385 42.1 5.82 HVO_2464 succinate--CoA ligase (ADP-forming) alpha subunit 48.79 1 9 9 221 3.886E8 350.40 45.67 8 107 16332.29 48.79 9 114 289 29.8 4.27 HVO_2948 phenylalanine--tRNA ligase alpha subunit 48.70 1 12 12 176 1.251E8 301.18 47.70 11 87 11895.30 48.70 12 89 499 55.1 4.41 HVO_2204 "FtsZ family protein, type III" 48.10 1 13 15 271 3.879E8 359.57 48.10 15 136 15337.06 48.10 15 135 395 42.0 4.68 HVO_1522 hexuronic acid methyltransferase AglP 47.70 1 9 9 84 1.098E8 89.38 47.70 9 42 4300.15 47.70 9 42 239 26.2 4.98 HVO_3007 malate dehydrogenase 47.37 1 12 12 247 6.528E8 297.22 47.37 12 123 12067.85 47.37 12 124 304 32.6 4.40 HVO_2471 propionyl-CoA carboxylase carboxyltransferase component 47.29 1 20 20 361 1.786E8 504.08 47.29 20 177 22178.63 47.29 20 184 516 56.7 4.89 17318569 keratin 1 [Homo sapiens] 47.20 1 1 25 327 2.224E8 503.55 47.20 25 163 22532.95 47.20 25 164 644 66.0 8.12 HVO_1020 HEAT-PBS family protein 47.02 1 17 18 596 1.428E9 839.33 42.72 16 290 43282.89 47.02 18 306 419 45.5 3.95 HVO_2436 malic enzyme (NADP) 47.00 1 20 28 521 4.414E8 675.56 47.00 28 258 32705.80 47.00 28 263 751 81.4 4.55 HVO_2013 "FtsZ family protein, type III" 46.95 1 10 11 117 1.182E8 177.29 46.95 11 58 7768.44 45.69 10 59 394 41.5 4.61 HVO_2695 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 46.88 1 14 14 319 3.840E8 452.75 42.19 13 163 19305.21 46.88 14 156 512 55.4 4.42 HVO_0859 FeS assembly ATPase SufC 46.51 1 11 11 137 1.139E8 115.98 46.51 11 68 6677.17 46.51 11 69 301 33.4 4.35 HVO_2561 50S ribosomal protein L2 46.47 1 16 16 565 2.770E9 700.00 46.47 16 282 35081.68 46.47 16 283 241 25.6 10.40 HVO_2163 ABC-type transport system ATP-binding protein (homolog to LolDCE lipoprotein release factor) 46.18 1 7 8 56 3.902E7 78.56 46.18 8 28 3127.80 46.18 8 28 249 26.7 6.90 HVO_2784 30S ribosomal protein S13 46.11 1 6 6 75 6.608E8 88.36 46.11 6 38 4689.71 46.11 6 37 167 18.9 5.17 HVO_0836 probable M28 family peptidase (homolog to aminopeptidase YwaD) 45.98 1 13 14 262 2.341E8 402.99 41.61 13 130 17689.79 45.98 14 132 435 46.9 4.63 1346343 "Keratin, type II cytoskeletal 1 (Cytokeratin-1) (CK-1) (Keratin-1) (K1) (67 kDa cytokeratin) (Hair alpha protein)" 45.81 1 0 24 319 2.224E8 496.60 45.81 24 159 22238.33 45.81 24 160 644 66.0 8.12 HVO_0167 adenosylhomocysteinase 45.33 1 12 12 148 2.298E8 209.71 41.12 11 69 11298.26 37.85 10 79 428 46.6 4.39 HVO_1575 arginase 45.15 1 9 9 71 1.236E8 89.17 45.15 9 36 3402.87 45.15 9 35 299 31.0 4.58 HVO_2053 "probable glycosyltransferase, type 1" 44.97 1 11 11 95 5.489E7 108.84 44.97 11 47 5135.47 35.45 10 48 378 41.9 4.67 HVO_2552 30S ribosomal protein S4e 44.94 1 7 7 131 6.438E8 174.46 44.94 7 65 7599.91 44.94 7 66 247 26.6 4.58 HVO_2015 conserved hypothetical protein 44.93 1 11 11 206 3.061E8 249.17 44.93 11 102 13368.37 44.93 11 104 345 37.7 4.25 HVO_2553 50S ribosomal protein L24 44.92 1 5 5 45 2.470E8 59.41 44.92 5 23 2946.54 44.92 5 22 118 13.4 4.73 HVO_1692 probable iron-sulfur protein (4Fe-4S) 44.75 1 27 27 428 5.637E8 568.52 44.75 26 212 26616.33 40.52 26 216 733 80.2 4.49 HVO_2205 arNOG06768 family NADH-binding domain protein 44.52 1 9 10 122 3.543E7 202.33 39.53 9 61 7848.61 44.52 10 61 301 32.0 5.00 HVO_0704 "probable glycosyltransferase, type 2" 44.06 1 7 7 84 3.290E7 111.33 37.55 6 41 4287.37 44.06 7 43 261 28.4 5.30 HVO_0059 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 43.73 1 10 11 98 8.651E7 111.02 43.73 11 48 4764.52 42.62 10 50 359 39.4 4.91 HVO_2606 PQQ repeat protein 43.71 1 17 18 166 1.101E8 153.35 42.56 17 85 7603.78 32.04 16 81 437 46.9 4.81 HVO_0354 30S ribosomal protein S7 43.63 1 6 6 43 5.747E7 49.45 34.80 5 16 4389.80 40.20 5 27 204 22.6 5.14 HVO_1373 acyl-CoA dehydrogenase 43.60 1 10 10 140 1.119E8 187.51 43.60 10 70 8488.16 43.60 10 70 383 42.5 4.61 HVO_1396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 43.52 1 14 14 210 2.178E8 270.65 43.52 14 104 11388.25 43.52 14 106 471 51.0 4.48 HVO_1502 3-isopropylmalate dehydrogenase 43.52 1 10 10 125 1.346E8 140.83 35.80 9 57 7960.48 43.52 10 68 324 33.7 4.23 HVO_2809 succinate dehydrogenase subunit B (iron-sulfur protein) 43.34 1 14 14 266 2.792E8 256.61 36.18 13 132 13622.95 43.34 14 134 293 33.9 5.27 HVO_1082 homolog to orotate phosphoribosyltransferase 43.33 1 6 6 29 2.110E7 32.11 43.33 6 15 1543.49 43.33 6 14 210 22.3 4.42 HVO_2126 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 43.28 1 24 24 569 5.729E8 828.41 40.49 23 285 35894.29 43.11 23 284 573 62.9 4.45 HVO_2646 dihydroxy-acid dehydratase 43.15 1 17 17 220 2.030E8 227.04 43.15 17 109 10837.67 43.15 17 111 584 61.8 4.42 HVO_1921 serine--tRNA ligase 43.04 1 13 13 139 4.422E7 165.86 43.04 13 68 7289.99 43.04 13 71 460 52.0 4.46 HVO_1955 aconitate hydratase 42.97 1 22 22 295 3.934E8 405.41 41.13 20 147 18409.13 42.97 22 148 654 70.4 4.45 HVO_2997 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 42.69 1 10 10 200 2.999E8 289.12 40.14 9 98 12931.97 42.69 10 102 431 46.1 4.48 HVO_1673 conserved hypothetical protein 42.59 1 7 7 47 9.579E7 53.78 38.43 6 24 2547.04 42.59 7 23 216 23.2 4.58 HVO_0861 SufB domain protein 42.54 1 13 13 209 9.719E7 354.56 42.54 13 106 15670.45 40.05 12 103 402 44.7 4.23 HVO_2524 phytoene synthase 42.48 1 11 11 107 9.835E7 119.63 42.48 11 53 5918.24 42.48 11 54 339 38.3 4.82 HVO_2968 phosphoglycerate dehydrogenase 42.48 1 15 15 147 1.754E8 235.41 42.48 15 74 10593.63 42.48 15 73 525 55.3 4.36 HVO_2621 phosphoenolpyruvate carboxylase 42.25 1 32 32 323 1.884E8 364.56 41.25 30 162 17911.40 42.25 32 161 897 102.3 4.64 HVO_0035 stomatin family protein 42.14 1 7 13 158 5.897E8 217.77 42.14 13 79 9895.35 42.14 13 79 401 43.6 4.65 HVO_2225 AstE family protein 41.94 1 8 8 53 6.720E7 70.66 34.02 7 26 2523.77 39.88 7 27 341 36.9 4.53 HVO_0316 A-type ATP synthase subunit A 41.81 1 19 19 430 5.217E8 607.78 41.81 19 215 26348.59 41.30 18 215 586 64.5 4.25 HVO_2481 HD family hydrolase 41.79 1 9 9 54 1.465E7 26.05 41.79 9 27 1722.47 41.79 9 27 390 42.7 6.14 HVO_0627 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 41.76 1 27 28 407 3.860E8 506.49 41.76 28 207 22505.01 39.20 27 200 898 97.7 4.45 HVO_2544 30S ribosomal protein S5 41.12 1 9 9 63 9.918E7 81.05 34.58 7 31 4189.08 38.32 8 32 214 23.3 9.29 HVO_2384 CBS domain protein 41.05 1 11 12 87 3.412E7 85.63 41.05 12 44 4398.04 39.74 11 43 380 42.5 5.01 HVO_1831 ferredoxin (2Fe-2S) 40.93 1 4 4 137 4.796E8 228.65 22.28 3 67 9320.51 40.93 4 70 193 20.4 3.98 HVO_0860 SufB domain protein 40.76 1 16 16 160 1.474E8 173.02 40.76 15 80 7915.99 36.76 14 80 476 53.2 4.69 HVO_2778 50S ribosomal protein L13 40.69 1 5 5 90 6.575E7 150.53 40.69 5 45 7459.83 40.69 5 45 145 16.0 5.43 HVO_1778 catalase-peroxidase 40.53 1 21 21 351 6.425E8 433.70 39.97 20 174 19282.52 39.97 20 177 718 80.0 4.31 HVO_B0134 ABC-type transport system ATP-binding protein 40.31 1 6 6 23 4.578E7 25.57 34.50 5 10 1180.46 40.31 6 13 258 27.2 4.53 HVO_2758 50S ribosomal protein L11 40.25 1 5 5 67 1.754E8 86.08 32.70 4 31 3741.61 30.82 4 36 159 16.8 4.04 HVO_A0133 conserved hypothetical protein 40.07 1 10 10 184 2.367E8 328.91 33.56 9 93 13708.46 40.07 10 91 292 30.8 5.17 HVO_0869 glutamate synthase large subunit 39.97 1 46 47 439 1.174E8 502.61 39.25 45 217 23392.67 39.97 47 222 1511 163.8 4.70 HVO_1590 DnaK-type molecular chaperone Hsp70 39.84 1 21 21 267 3.675E8 350.90 39.84 21 134 15273.49 38.72 20 133 625 67.2 4.18 HVO_1061 oxidoreductase (homolog to thioredoxin-disulfide reductase) 39.77 1 7 7 40 1.553E7 59.53 39.77 7 21 2450.74 39.77 7 19 259 28.0 4.50 HVO_1684 threonine--tRNA ligase 39.66 1 23 23 227 1.495E8 253.59 39.66 23 113 13047.88 35.77 22 114 643 73.4 4.45 40354192 keratin 10 [Homo sapiens] 39.55 1 0 21 187 7.396E7 238.34 39.55 21 93 10266.74 39.55 21 94 584 58.8 5.16 HVO_2783 30S ribosomal protein S4 39.43 1 7 7 56 2.493E7 49.24 39.43 7 28 3292.27 39.43 7 28 175 20.1 5.24 81175178 "Keratin, type I cytoskeletal 9 (Cytokeratin-9) (CK-9) (Keratin-9) (K9)" 39.33 1 18 19 109 7.270E7 119.40 39.33 19 55 5004.37 36.44 17 54 623 62.1 5.30 HVO_2947 phenylalanine--tRNA ligase beta subunit 39.30 1 16 17 171 2.457E8 127.65 37.19 15 79 8640.55 39.30 17 92 570 63.3 4.46 HVO_2546 50S ribosomal protein L19e 39.07 1 6 6 45 5.792E7 60.03 39.07 6 23 2900.19 34.44 5 22 151 17.3 9.98 547749 "Keratin, type I cytoskeletal 10 (Cytokeratin-10) (CK-10) (Keratin-10) (K10)" 38.95 1 0 21 187 7.396E7 238.34 38.95 21 93 10266.74 38.95 21 94 593 59.5 5.21 HVO_1538 glycerol-3-phosphate dehydrogenase subunit A 38.91 1 19 19 240 2.898E8 253.19 38.05 18 119 12915.08 38.91 19 121 586 63.4 4.70 HVO_0087 porphobilinogen synthase 38.84 1 9 9 128 1.599E8 125.84 38.84 9 65 6111.68 38.84 9 63 327 35.3 4.72 HVO_2452 "ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent" 38.72 1 32 32 376 1.407E8 445.33 37.27 31 189 20183.97 37.46 31 187 1033 114.3 4.45 HVO_A0472 oxidoreductase (homolog to thioredoxin-disulfide reductase) 38.66 1 5 5 112 1.546E8 90.85 38.66 5 54 4869.61 38.66 5 58 194 20.7 4.12 HVO_1697 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 38.60 1 34 38 440 2.635E8 507.56 38.60 38 220 25655.24 38.60 38 220 1026 111.2 4.54 HVO_1788 probable sulfite/nitrite reductase (ferredoxin) 38.51 1 16 16 124 1.274E8 170.32 38.51 16 62 7321.73 38.51 16 62 592 66.6 4.61 HVO_2123 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 38.27 1 9 9 56 2.979E7 70.17 31.28 8 27 2721.06 38.27 9 29 358 38.8 4.61 HVO_2519 conserved hypothetical protein 37.96 1 8 8 97 2.193E7 157.35 33.25 7 46 7612.92 37.96 8 51 382 40.7 4.35 HVO_2558 30S ribosomal protein S3 37.83 1 9 9 86 9.287E7 109.27 33.55 8 41 6021.61 37.83 9 45 304 33.4 4.06 HVO_0908 conserved hypothetical protein 37.82 1 2 2 18 7.487E6 31.24 37.82 2 9 1003.21 37.82 2 9 119 12.6 4.22 HVO_0684 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B 37.70 1 10 10 74 4.256E7 86.83 37.70 10 37 3247.19 37.70 10 37 496 55.0 4.53 HVO_1637 FKBP-type peptidylprolyl isomerase 37.58 1 6 7 65 1.939E8 84.27 29.08 6 29 4118.93 35.95 5 36 306 33.8 3.76 HVO_2643 NADPH:quinone reductase 37.57 1 9 9 91 6.502E7 93.73 32.66 7 43 4847.29 37.57 9 48 346 37.2 4.55 HVO_B0062 precorrin-7 15-methyltransferase (decarboxylating) 37.50 1 5 5 21 2.233E6 24.54 37.50 5 11 907.63 34.24 4 10 184 19.8 5.30 HVO_1508 acetolactate synthase large subunit 37.48 1 14 14 410 5.895E8 600.74 37.48 14 205 24828.99 37.48 14 205 587 62.3 4.36 HVO_1084 adenylosuccinate lyase 37.37 1 15 15 97 8.386E7 87.60 36.29 14 45 4922.11 37.37 15 52 463 50.8 4.70 HVO_1546 dihydroxyacetone kinase subunit DhaK 37.35 1 11 11 105 1.002E8 115.05 37.35 11 52 4709.46 37.35 11 53 332 34.8 4.22 HVO_1577 conserved hypothetical protein 37.29 1 3 3 12 1.905E7 17.42 37.29 3 7 417.94 16.95 2 5 177 19.4 4.74 HVO_1132 adenylosuccinate synthase 37.25 1 16 16 202 1.886E8 243.25 34.09 15 99 13807.51 37.25 16 103 443 48.2 4.56 HVO_1099 "2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase" 37.14 1 8 8 54 2.698E7 63.92 37.14 8 27 3565.99 37.14 8 27 280 30.1 4.44 HVO_2402 glycine dehydrogenase (decarboxylating) (glycine cleavage system protein P) 36.91 1 12 12 192 1.699E8 255.84 36.91 12 96 11949.25 36.91 12 96 447 48.5 4.56 HVO_2960 dihydrolipoamide S-acyltransferase 36.85 1 18 18 305 1.544E8 429.97 36.08 17 153 19482.41 36.85 18 152 521 54.9 4.40 HVO_1829 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 36.81 1 9 10 105 9.724E7 158.55 36.81 10 53 7998.11 35.71 9 52 364 39.3 4.35 HVO_2430 ABC-type transport system ATP-binding protein (probable substrate glutamine) 36.78 1 6 8 109 6.917E7 131.46 32.64 7 52 6443.11 36.78 8 57 242 26.6 4.88 HVO_2959 2-oxo-3-methylvalerate dehydrogenase E1 component beta subunit 36.70 1 10 10 60 4.844E7 68.63 33.03 9 28 3853.07 36.70 10 32 327 36.0 4.73 HVO_0348 DNA-directed RNA polymerase subunit B' 36.62 1 16 16 130 4.808E7 182.66 35.47 15 66 6425.48 36.62 16 64 609 67.7 4.92 HVO_2690 GFO family oxidoreductase 36.61 1 10 10 103 1.602E8 88.25 36.61 10 52 5228.85 36.61 10 51 366 40.0 4.60 HVO_2923 proteasome alpha subunit 36.55 1 7 8 98 1.316E8 124.43 36.55 8 50 5109.85 36.55 8 48 249 26.7 4.39 HVO_1465 naphthoate synthase 36.39 1 8 8 92 5.435E7 101.85 27.87 7 42 5540.57 36.39 8 50 305 33.9 4.83 HVO_2413 translation elongation factor aEF-1 alpha subunit 36.19 1 8 11 71 1.042E7 69.44 31.90 10 34 3934.46 36.19 11 37 420 45.6 4.75 HVO_1212 KaiC-type circadian regulator CirA 36.18 1 8 8 79 7.619E7 110.23 36.18 8 40 4958.26 36.18 8 39 246 27.5 4.45 HVO_A0156 acyl-CoA synthetase 35.99 1 7 16 161 1.408E8 216.16 34.49 15 79 10305.34 31.63 15 82 664 74.0 4.40 HVO_2716 acyl-CoA dehydrogenase 35.96 1 10 10 115 3.631E7 180.82 34.12 9 57 6795.23 35.96 10 58 381 41.3 4.65 HVO_0843 conserved hypothetical protein 35.66 1 6 6 32 4.664E7 41.70 30.23 5 14 1584.32 35.66 6 18 129 14.7 5.57 HVO_C0074 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 35.65 1 16 17 80 3.935E7 73.86 34.64 16 40 3895.82 30.87 16 40 690 75.9 4.79 HVO_1062 phosphopantothenoylcysteine decarboxylase / phosphopantothenate--cysteine ligase 35.23 1 9 9 143 6.390E7 202.49 35.23 9 71 8722.50 35.23 9 72 386 40.0 4.68 HVO_1871 UPF0447 family protein 35.13 1 18 18 399 5.753E8 428.78 31.74 17 196 21577.24 34.13 17 203 501 56.1 4.59 HVO_B0111 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 34.91 1 12 12 139 7.248E7 168.15 34.91 12 70 6204.72 34.91 12 69 401 44.2 4.54 HVO_0960 probable oxidoreductase (aldo-keto reductase family protein) 34.88 1 6 6 67 1.913E7 88.79 34.88 6 33 4002.94 34.88 6 34 281 30.6 4.59 HVO_0829 peptidase S9 family protein 34.87 1 13 13 67 2.912E7 61.24 34.87 13 34 2622.38 32.57 12 33 608 67.4 4.54 HVO_0824 "probable glycosyltransferase, type 1" 34.66 1 8 8 46 6.090E7 52.44 34.66 8 22 2510.30 34.66 8 24 352 39.6 5.08 HVO_0601 homoserine dehydrogenase 34.49 1 7 7 39 3.488E7 60.43 34.49 7 20 2608.67 34.49 7 19 316 32.2 4.25 HVO_0729 inorganic pyrophosphatase 34.46 1 6 6 110 3.337E8 131.68 34.46 6 56 5432.44 34.46 6 54 177 20.4 4.16 HVO_2432 ABC-type transport system periplasmic substrate-binding protein (probable substrate glutamine) 34.34 1 7 7 442 6.339E8 721.72 34.34 7 222 30369.94 34.34 7 220 297 32.3 3.98 HVO_0581 "cell division protein FtsZ, type II" 34.25 1 9 9 85 3.764E7 133.85 32.00 8 42 5212.71 34.25 9 43 400 42.5 4.75 HVO_1693 conserved hypothetical protein 34.13 1 3 3 19 1.115E7 23.28 25.75 2 9 814.29 34.13 3 10 167 17.3 4.35 HVO_0850 proteasome-activating nucleotidase 34.07 1 9 11 107 2.929E7 114.00 28.89 10 53 5526.99 34.07 11 54 405 45.6 4.60 HVO_3014 origin-associated GTP-binding protein OapA 33.80 1 7 7 30 1.400E7 26.63 23.94 5 13 1810.42 33.80 7 17 213 24.0 5.01 HVO_0654 50S ribosomal protein L43e 33.71 1 2 2 31 3.957E7 11.19 33.71 2 16 1173.03 33.71 2 15 89 9.9 9.98 HVO_0046 putative glutamate--argW ligase 33.68 1 6 7 31 1.326E7 23.69 33.68 7 16 1290.27 33.68 7 15 291 31.9 4.87 HVO_1568 alpha/beta hydrolase fold protein 33.57 1 6 6 36 9.358E6 45.61 33.57 6 18 1737.72 33.57 6 18 277 29.4 4.94 HVO_1541 glycerol kinase 33.53 1 13 13 103 1.440E8 110.69 30.20 12 48 6737.77 33.53 13 55 510 56.7 4.50 HVO_0008 aspartate kinase 33.42 1 6 6 35 3.339E7 48.99 33.42 6 18 1581.81 25.77 5 17 392 41.7 4.46 HVO_0743 probable phosphodiesterase 33.41 1 14 14 128 5.598E7 98.56 33.41 14 61 5283.09 33.41 14 67 449 50.5 4.56 HVO_0466 citrate (si)-synthase 33.25 1 10 10 128 5.850E7 212.67 31.93 9 64 8486.18 33.25 10 64 379 41.8 4.55 HVO_0233 ribose-phosphate pyrophosphokinase 33.22 1 5 5 43 1.908E7 59.63 33.22 5 22 1734.04 33.22 5 21 283 29.6 4.40 HVO_0561 50S ribosomal protein L15e 33.16 1 8 8 183 8.200E8 146.52 33.16 8 92 9312.41 33.16 8 91 196 22.5 11.15 HVO_A0039 hypothetical protein 33.13 1 10 10 212 5.366E8 345.02 33.13 10 107 16534.61 32.82 9 105 326 35.6 4.60 HVO_2625 GMP synthase (glutamine-hydrolyzing) subunit B 33.11 1 8 8 53 6.558E7 57.19 33.11 8 26 2435.65 33.11 8 27 305 33.8 4.74 HVO_0062 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 33.01 1 12 12 842 2.651E9 997.90 33.01 12 420 47344.84 33.01 12 422 612 67.3 4.16 HVO_1453 glutamate dehydrogenase (NADP) 32.85 1 12 12 154 7.063E7 166.54 32.85 12 78 8117.40 32.85 12 76 417 45.7 4.49 HVO_2770 conserved hypothetical protein 32.81 1 8 8 104 1.122E8 95.66 32.81 8 53 6187.92 32.81 8 51 320 35.7 5.15 HVO_1018 RecJ domain protein 32.70 1 17 19 178 1.241E8 202.21 32.70 19 90 10372.99 29.54 18 88 633 69.8 4.58 HVO_2913 superoxide dismutase (Mn) 32.66 1 0 4 74 1.903E8 109.61 32.66 4 37 5479.65 32.66 4 37 199 22.3 4.48 HVO_2737 50S ribosomal protein L8e 32.50 1 3 3 12 3.515E6 4.32 32.50 3 6 521.02 32.50 3 6 120 12.6 4.16 HVO_A0475 superoxide dismutase (Mn) 32.50 1 0 4 74 1.903E8 109.61 32.50 4 37 5479.65 32.50 4 37 200 22.4 4.45 HVO_2049 "probable glycosyltransferase, type 2" 32.25 1 6 6 33 6.734E7 33.73 20.85 5 15 1552.27 32.25 6 18 307 35.3 5.40 HVO_1570 DNA topoisomerase VI subunit A 32.24 1 7 7 32 4.245E7 34.81 32.24 7 16 1565.32 32.24 7 16 366 41.8 4.63 HVO_3002 ABC-type transport system ATP-binding protein 32.21 1 9 9 120 1.746E8 131.77 29.14 8 55 7659.10 32.21 9 65 326 34.7 4.31 HVO_1603 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfonate) 32.18 1 5 5 137 7.822E7 213.20 32.18 5 67 7629.28 32.18 5 70 348 37.2 4.35 HVO_2743 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 32.14 1 10 10 55 5.944E7 74.15 24.70 8 25 3817.28 32.14 9 30 336 36.8 4.12 HVO_0894 acyl-CoA synthetase 31.87 1 7 16 155 1.205E8 159.34 30.36 15 77 8353.05 27.49 15 78 662 74.3 4.48 HVO_0446 ABC-type transport system ATP-binding protein (probable substrate phosphate/phosphonate) 31.84 1 6 8 89 5.782E7 125.99 28.09 7 43 6789.32 31.84 8 46 267 28.9 4.64 HVO_2461 CBS domain protein 31.72 1 1 2 3 2.727E6 0.00 31.72 2 3 145 15.5 5.64 HVO_0717 "cell division protein FtsZ, type I" 31.66 1 10 10 87 2.283E8 106.83 31.66 10 43 5814.03 31.66 10 44 379 39.8 4.40 HVO_1443 ABC-type transport system ATP-binding protein 31.52 1 7 9 51 1.273E7 35.20 31.52 9 26 1887.69 31.52 9 25 330 36.3 4.70 HVO_A0331 D-galactonate dehydratase 31.51 1 7 7 49 1.808E7 74.89 24.22 6 24 3440.29 31.51 7 25 384 42.8 4.83 HVO_0832 alpha/beta hydrolase fold protein 31.49 1 8 8 122 3.882E8 137.43 23.05 6 60 6968.12 31.49 8 62 308 33.3 4.67 HVO_1562 proteasome beta subunit 31.28 1 6 6 135 1.312E8 176.19 31.28 6 70 7705.69 31.28 6 65 243 26.0 4.63 HVO_0966 "ribose-1,5-bisphosphate isomerase (ribulose-bisphosphate forming)" 31.27 1 7 7 41 1.993E7 63.76 26.01 6 20 2921.75 31.27 7 21 323 34.9 5.24 HVO_1006 ABC-type transport system ATP-binding protein 31.23 1 4 5 26 2.304E7 12.54 31.23 5 13 848.49 31.23 5 13 317 32.7 4.39 HVO_2345 flavin-dependent pyridine nucleotide oxidoreductase 31.23 1 10 10 49 4.001E7 28.17 28.09 9 23 1422.26 31.23 10 26 413 45.8 4.45 HVO_1495 "phosphotransferase system component IIB, fructose-specific" 31.01 1 2 2 22 1.050E7 36.68 31.01 2 11 1541.33 31.01 2 11 158 16.3 4.46 HVO_0353 30S ribosomal protein S12 30.99 1 5 5 21 1.644E7 26.50 30.99 5 12 893.50 23.24 3 9 142 15.5 9.91 HVO_2356 GNAT family acetyltransferase 30.96 1 8 8 64 2.026E7 82.82 30.96 8 34 3559.89 25.06 6 30 407 45.1 4.64 HVO_0045 N-acetyl-gamma-glutamyl-phosphate reductase 30.84 1 10 10 80 1.017E8 93.80 25.07 9 40 4192.39 30.84 10 40 347 36.8 4.93 HVO_2750 "cystathionine synthase/lyase (cystathionine gamma-synthase, cystathionine gamma-lyase, cystathionine beta-lyase)" 30.83 1 6 6 68 5.631E7 56.49 30.83 6 33 2947.33 30.83 6 35 386 42.1 4.49 HVO_1917 acyl-CoA synthetase 30.78 1 16 16 72 2.963E7 73.70 29.88 15 36 3267.03 29.43 15 36 666 74.0 4.78 HVO_2675 histidinol dehydrogenase 30.61 1 7 7 34 2.190E7 40.74 30.61 7 17 1539.91 28.97 6 17 428 45.4 4.50 HVO_A0428 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 30.51 1 10 10 72 4.230E7 77.26 26.10 9 35 3564.41 30.51 10 37 567 62.4 4.70 7428712 "keratin 1, type II, cytoskeletal - human" 30.33 1 0 18 269 1.888E8 413.29 30.33 18 134 18403.24 30.33 18 135 643 65.5 6.35 >sp|TRYP_PIG| 30.30 1 7 7 842 1.435E10 1439.12 28.57 6 419 64956.24 30.30 7 423 231 24.4 7.18 HVO_2008 archaeosine synthase 30.26 1 19 19 128 7.878E7 150.61 28.03 17 62 7374.58 30.26 19 66 585 64.9 4.81 HVO_A0206 CRISPR-associated protein Cas8b 30.13 1 15 15 101 7.040E7 108.98 30.13 15 51 5003.95 30.13 15 50 717 79.3 4.60 HVO_0783 ATP-dependent protease La 30.12 1 14 14 75 6.995E7 75.48 27.81 12 38 3727.35 29.25 13 37 694 75.4 4.86 HVO_B0200 malate synthase 30.05 1 9 9 97 9.718E7 131.89 30.05 9 48 5719.31 30.05 9 49 436 48.3 4.30 HVO_2773 30S ribosomal protein S2 30.00 1 4 4 79 8.163E7 135.59 30.00 4 39 6305.58 30.00 4 40 260 28.3 4.16 HVO_1478 transcription initiation factor TFB 29.97 1 6 9 71 5.121E7 68.79 29.97 9 36 2982.75 28.08 8 35 317 35.7 5.47 HVO_0809 methionine--tRNA ligase 29.86 1 13 13 82 4.534E7 104.25 29.86 13 41 4122.12 29.86 13 41 740 81.9 4.37 HVO_2070 conserved hypothetical protein 29.78 1 12 12 383 4.806E8 662.39 29.78 12 192 28776.83 29.78 12 191 544 58.1 4.50 HVO_1854 histidine--tRNA ligase 29.70 1 9 9 65 3.428E7 93.17 29.70 9 34 3305.97 24.36 8 31 431 47.1 4.37 HVO_2191 formyltetrahydrofolate deformylase 29.66 1 5 5 38 4.221E7 48.53 18.96 4 19 2248.06 29.66 5 19 327 36.2 4.63 HVO_A0487 "cobyrinic acid a,c-diamide synthase" 29.64 1 8 8 48 3.624E7 66.91 23.98 7 24 2649.54 25.79 7 24 442 46.9 4.58 HVO_1164 HD family hydrolase 29.63 1 7 7 46 3.214E7 20.20 29.63 7 23 1730.83 29.63 7 23 270 29.8 4.87 HVO_1824 conserved hypothetical protein 29.60 1 8 8 52 1.855E7 85.42 24.48 7 26 3333.56 29.60 8 26 429 47.4 4.20 HVO_1242 conserved hypothetical protein 29.40 1 8 8 52 2.557E7 75.29 29.40 8 26 3131.64 29.40 8 26 432 47.1 4.75 HVO_2886 GNAT family acetyltransferase 29.25 1 2 2 2 1.527E7 0.00 29.25 2 2 147 16.3 4.60 HVO_0393 UvrABC system protein A 29.20 1 18 18 96 4.783E7 110.02 28.18 17 47 4433.13 29.20 18 49 983 108.6 4.82 HVO_2168 AAA-type ATPase (MoxR subfamily) 29.18 1 7 7 40 3.553E7 32.41 29.18 7 20 1732.53 29.18 7 20 329 35.9 4.54 HVO_1023 conserved hypothetical protein 29.15 1 6 6 32 3.160E7 50.38 29.15 6 16 2143.45 29.15 6 16 271 30.2 4.63 HVO_0203 replication factor C small subunit 29.05 1 8 8 34 3.152E7 41.46 29.05 8 17 2050.33 29.05 8 17 327 36.2 4.51 HVO_0049 argininosuccinate synthase 28.89 1 9 9 113 2.838E8 126.95 28.89 9 56 5934.07 28.89 9 57 405 44.5 4.34 HVO_0402 DUF124 family protein 28.89 1 4 4 31 1.058E7 31.54 28.89 4 16 991.61 20.00 3 15 225 24.0 4.58 HVO_2989 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 28.85 1 10 11 74 2.859E7 89.34 27.97 10 36 4260.75 28.85 11 38 454 48.5 4.46 HVO_2624 CTP synthase 28.78 1 11 11 71 3.753E7 54.75 26.78 10 30 3977.02 28.78 11 41 549 60.8 4.70 HVO_1228 halocyanin 28.75 1 15 15 241 1.888E8 340.52 28.75 15 122 15272.16 28.75 15 119 821 83.7 4.17 HVO_0865 FkbM family methyltransferase 28.57 1 6 6 48 3.036E7 57.70 28.57 6 26 1917.13 28.57 6 22 252 27.7 5.49 HVO_1727 TATA-binding transcription initiation factor 28.49 1 4 5 40 8.387E6 36.38 28.49 5 20 2272.04 28.49 5 20 186 19.9 4.36 HVO_B0093 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 28.48 1 13 13 148 5.985E7 192.87 28.48 13 74 7789.19 28.48 13 74 618 69.1 4.45 HVO_0711 conserved hypothetical protein 28.24 1 7 7 58 7.890E7 62.54 21.30 5 23 4497.70 28.24 7 35 216 23.1 3.81 HVO_1626 homolog to UPF0173 family metal-dependent hydrolase 27.80 1 5 5 25 8.500E6 27.01 23.83 4 10 1928.59 27.80 5 15 277 30.6 4.30 HVO_1548 conserved hypothetical protein 27.72 1 3 3 14 4.073E6 19.19 27.72 3 7 758.78 27.72 3 7 202 22.2 4.96 HVO_C0075 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 27.60 1 11 11 42 2.862E7 43.15 27.60 11 20 1694.90 27.60 11 22 558 61.3 4.56 HVO_1987 signal peptide peptidase 27.42 1 8 8 64 1.393E8 78.06 27.42 7 31 4297.18 27.09 7 33 299 31.3 4.56 HVO_2551 50S ribosomal protein L5 27.33 1 5 5 103 6.632E7 140.33 20.35 3 47 7444.05 27.33 5 56 172 19.1 4.78 HVO_2059 NAD-dependent epimerase/dehydratase 27.10 1 5 5 20 2.630E7 17.13 15.81 4 9 841.92 27.10 5 11 310 34.1 4.40 HVO_2016 conserved hypothetical protein 27.09 1 7 7 56 2.400E7 80.37 27.09 7 28 3301.41 26.76 6 28 299 31.2 4.70 HVO_0122 phosphoglycerate dehydrogenase 26.85 1 6 6 43 2.912E7 31.81 26.85 6 21 2109.16 26.85 6 22 324 35.3 5.35 HVO_2040 NAD-dependent epimerase/dehydratase 26.80 1 3 6 77 1.732E7 82.82 26.80 6 39 4072.32 22.55 5 38 306 33.8 4.51 HVO_0881 signal peptide peptidase 26.73 1 7 7 48 3.655E7 73.58 24.92 6 23 2968.07 26.73 7 25 333 35.2 4.37 HVO_0307 conserved hypothetical protein 26.57 1 10 11 95 6.541E7 113.46 26.57 11 50 4145.50 26.57 11 45 463 49.0 4.88 HVO_2688 TrmB family transcription regulator 26.35 1 8 9 61 1.014E8 80.30 26.35 9 29 4192.59 26.35 9 32 353 39.3 4.58 HVO_2742 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase (methionine synthase II) 26.33 1 9 10 116 1.030E8 132.55 26.33 10 60 5597.44 26.33 10 56 357 40.3 4.40 HVO_B0047 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 26.25 1 8 9 134 2.984E8 164.90 26.25 9 63 7678.51 24.75 8 71 400 44.2 4.32 HVO_1540 glycerol-3-phosphate dehydrogenase subunit C 26.15 1 10 11 176 2.108E8 239.96 26.15 11 88 12714.99 26.15 11 88 436 48.6 4.61 HVO_2782 30S ribosomal protein S11 26.15 1 3 3 44 2.212E7 34.40 26.15 3 22 2270.42 26.15 3 22 130 13.4 8.56 HVO_2316 serpin family protein 26.05 1 11 11 83 3.975E7 65.60 26.05 11 39 4267.24 26.05 11 44 453 48.7 4.25 HVO_1804 nicotinate phosphoribosyltransferase 26.03 1 8 8 78 7.482E7 113.35 26.03 8 39 5620.20 26.03 8 39 388 41.1 4.60 HVO_2511 glutamyl-tRNA(Gln) amidotransferase subunit D 26.02 1 7 7 121 1.927E8 180.33 26.02 7 60 7861.87 26.02 7 61 415 44.4 4.41 HVO_1245 probable disulfide bond formation protein 25.99 1 5 5 92 1.661E8 139.46 25.99 5 47 5392.02 25.99 5 45 227 24.2 4.50 HVO_2286 conserved hypothetical protein 25.94 1 6 6 33 1.371E7 47.48 19.50 5 16 1652.11 25.94 6 17 559 62.3 4.35 HVO_0357 ACT domain protein 25.93 1 4 5 21 1.510E7 24.97 22.75 4 10 1087.67 25.93 5 11 189 20.2 4.59 HVO_0447 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate/phosphonate) 25.86 1 5 5 157 2.871E7 124.05 25.86 5 76 4220.47 25.86 5 81 348 36.5 3.75 HVO_1025 acetyl-CoA C-acyltransferase 25.85 1 7 7 37 5.894E7 37.15 25.85 7 18 1894.97 25.85 7 19 383 40.7 4.56 HVO_1967 glucose-6-phosphate isomerase 25.81 1 7 7 74 8.664E7 109.82 25.81 7 37 4253.10 25.81 7 37 430 45.6 4.40 HVO_0841 cytochrome bc1 complex cytochrome b/c subunit 25.59 1 7 7 58 4.862E7 64.33 25.59 6 29 2558.11 25.59 7 29 254 28.8 5.72 HVO_1072 "purine phosphoribosyltransferase (adenine phosphoribosyltransferase, xanthine-guanine phosphoribosyltransferase)" 25.53 1 3 3 36 1.147E7 14.27 25.53 3 18 1342.15 25.53 3 18 188 20.5 4.60 HVO_0243 threonine aldolase 25.51 1 6 6 43 1.238E7 59.60 20.23 5 21 2918.44 25.51 6 22 341 35.6 4.55 HVO_1888 ABC-type transport system periplasmic substrate-binding protein (probable substrate sulfate/tungstate) 25.15 1 6 6 94 3.155E8 160.79 25.15 6 47 7305.21 25.15 6 47 342 35.9 4.34 HVO_0350 DNA-directed RNA polymerase subunit A'' 25.06 1 9 10 49 3.949E7 62.19 19.81 8 24 2437.92 22.67 9 25 419 46.1 4.35 HVO_1402 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 24.94 1 7 7 45 7.438E7 57.14 18.98 6 22 2501.17 24.94 7 23 453 47.5 4.63 HVO_2158 malic enzyme (NADP) 24.90 1 4 12 142 1.292E8 139.76 24.90 12 68 7421.97 24.90 12 74 751 81.4 4.55 HVO_0311 A-type ATP synthase subunit I 24.83 1 16 17 247 2.573E8 278.91 24.83 17 120 13924.61 24.15 16 127 733 79.5 4.41 HVO_A0168 HTH-10 family transcription regulator 24.80 1 2 2 14 1.212E7 322.08 24.80 2 14 246 27.8 4.98 HVO_1191 proline dehydrogenase 24.73 1 5 5 50 2.795E7 57.78 24.73 5 24 2766.44 24.73 5 26 279 31.0 5.02 HVO_2348 GTP cyclohydrolase MptA 24.68 1 5 5 25 1.241E7 26.72 18.51 4 12 1121.73 24.68 5 13 308 33.5 4.68 HVO_1988 conserved hypothetical protein 24.64 1 4 4 40 9.876E7 77.42 24.64 4 20 3231.37 24.64 4 20 349 35.2 4.25 HVO_0347 DNA-directed RNA polymerase subunit B'' 24.57 1 9 9 45 2.359E7 64.08 24.57 9 24 2492.97 16.89 7 21 521 58.9 5.00 HVO_1847 oligoendopeptidase PepF 24.54 1 10 10 44 1.705E7 67.18 20.87 9 22 2828.31 19.03 9 22 599 68.5 4.41 HVO_0306 conserved hypothetical protein 24.49 1 8 8 70 4.203E7 103.31 24.49 8 34 4809.78 24.49 8 36 392 42.1 4.30 HVO_2435 peptidase M24 family protein 24.46 1 5 5 17 1.451E7 14.66 18.48 4 7 863.79 24.46 5 10 368 40.0 4.53 HVO_0644 2-isopropylmalate synthase / (R)-citramalate synthase 24.41 1 9 10 46 2.815E7 72.42 24.41 10 24 2538.20 21.29 8 22 512 53.8 4.78 HVO_0058 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 24.32 1 9 11 85 2.423E7 126.56 20.95 10 42 5811.74 23.20 10 43 444 50.2 4.84 HVO_1022 NamA family oxidoreductase (homolog to old yellow enzyme) 24.31 1 8 8 25 1.419E7 23.19 18.51 6 11 1065.95 24.31 8 14 362 39.6 4.82 HVO_1100 4-hydroxy-tetrahydrodipicolinate reductase 24.11 1 4 4 35 1.934E7 15.94 19.37 3 15 1291.97 24.11 4 20 253 26.0 4.60 HVO_0441 probable metallo-beta-lactamase family hydrolase 24.04 1 1 2 3 2.144E6 3.02 24.04 2 3 208 22.7 4.51 HVO_2378 ABC-type transport system ATP-binding protein (probable substrate phosphate) 23.99 1 6 7 77 1.251E8 101.35 23.99 7 38 5621.90 23.99 7 39 296 32.6 4.44 HVO_1591 conserved hypothetical protein 23.86 1 3 3 18 2.827E7 31.80 23.86 3 9 985.61 23.86 3 9 264 28.7 5.50 HVO_1711 glucoamylase 23.83 1 28 28 180 7.789E7 191.93 23.83 28 89 8562.44 23.83 28 91 1511 166.1 4.64 HVO_0874 beta-lactamase domain protein 23.75 1 12 12 126 5.695E7 157.11 23.75 12 62 7851.68 23.75 12 64 640 71.9 5.14 HVO_B0051 ATP-dependent cobaltochelatase subunit ChlID 23.65 1 10 10 85 5.465E7 123.43 22.66 9 42 5813.72 19.55 9 43 706 73.3 4.39 HVO_1235 creatininase 23.48 1 4 4 67 1.507E7 73.43 23.48 4 32 3360.03 23.48 4 35 264 29.2 4.84 HVO_0002 signal peptidase I 23.34 1 4 4 38 2.265E7 46.30 23.34 4 19 1868.14 23.34 4 19 287 30.3 4.60 HVO_0774 "probable glycosyltransferase, type 2" 23.33 1 5 5 34 1.563E7 52.94 23.33 5 18 1732.46 16.67 3 16 300 32.3 6.44 HVO_1240 conserved hypothetical protein 23.23 1 6 6 35 4.057E7 34.27 23.23 6 17 1550.18 23.23 6 18 353 37.4 4.49 HVO_2607 PQQ repeat protein 23.15 1 6 6 31 4.133E7 37.48 19.46 5 14 1794.72 23.15 6 17 406 42.3 4.86 HVO_2614 uridine phosphorylase 23.14 1 4 4 50 2.807E7 76.25 23.14 4 26 2739.96 23.14 4 24 242 25.8 4.30 HVO_2579 nicotinate-nucleotide pyrophosphorylase (carboxylating) 23.13 1 6 6 26 7.706E6 25.87 23.13 6 13 1092.72 23.13 6 13 268 27.9 4.87 HVO_0433 F420H2:NADP oxidoreductase 22.97 1 3 3 7 5.794E6 2.39 17.57 2 3 258.48 22.97 3 4 222 23.3 4.72 HVO_1241 SCO1/SenC/PrrC family protein 22.87 1 3 3 60 5.797E7 77.56 22.87 3 32 3429.95 22.87 3 28 223 24.6 4.45 HVO_0154 conserved hypothetical protein 22.82 1 3 3 22 8.820E6 34.96 22.82 3 11 1287.73 22.82 3 11 149 15.8 4.31 HVO_2226 probable phosphoribosyltransferase (homolog to anthranilate phosphoribosyltransferase) 22.78 1 6 6 40 4.079E7 48.84 22.78 6 20 1904.78 22.78 6 20 360 39.6 4.39 HVO_0104 DNA repair and recombination protein RadA 22.74 1 6 6 36 2.151E7 40.91 17.49 5 17 2254.14 18.95 5 19 343 37.3 4.64 HVO_2813 RimK family protein 22.74 1 8 9 46 2.114E7 39.83 22.74 9 23 2448.54 22.74 9 23 453 49.0 4.73 HVO_2661 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 22.70 1 8 8 70 8.255E7 55.84 22.70 8 38 2144.44 22.70 8 32 370 41.9 4.48 HVO_1459 ThuA family protein 22.69 1 3 3 63 8.262E7 85.16 22.69 3 31 3634.90 22.69 3 32 238 26.8 4.67 HVO_1529 glycosyltransferase AglG 22.68 1 8 8 53 1.602E7 52.44 22.68 8 25 2250.12 22.68 8 28 313 35.8 4.59 HVO_2665 HpcH/HpaI aldolase family protein 22.64 1 5 5 23 9.204E6 23.42 18.87 4 10 852.20 22.64 5 13 265 28.3 4.50 HVO_1710 alpha amylase 22.60 1 13 13 76 2.873E7 75.76 22.60 13 39 3965.09 22.60 13 37 677 75.0 4.45 HVO_1944 conserved hypothetical protein 22.60 1 5 5 43 2.116E7 53.43 22.60 5 21 2205.91 22.60 5 22 416 43.0 4.22 HVO_B0060 precorrin-4 C11-methyltransferase 22.58 1 3 3 9 7.235E4 6.91 9.32 2 4 451.70 22.58 3 5 279 29.7 4.22 HVO_0109 cysteine desulfurase 22.54 1 7 7 50 1.695E7 52.16 22.54 7 25 2288.72 22.54 7 25 426 46.8 4.56 HVO_0826 peptidase M42 family protein 22.41 1 7 7 78 1.203E8 97.68 22.41 7 39 4067.28 22.41 7 39 348 37.7 4.54 HVO_1076 sugar nucleotidyltransferase 22.36 1 3 3 6 2.462E6 0.00 22.36 3 3 109.57 13.04 2 3 322 35.8 4.20 HVO_2638 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 22.32 1 8 8 80 3.006E7 97.67 22.32 8 40 5211.03 22.03 7 40 345 36.9 4.68 HVO_2047 conserved hypothetical protein 22.30 1 5 5 27 1.515E7 20.99 20.61 4 12 1488.30 22.30 5 15 296 34.2 4.93 HVO_1130 conserved hypothetical protein 22.28 1 2 2 17 2.408E7 2.32 22.28 2 8 472.49 22.28 2 9 193 20.1 4.78 HVO_A0181 conserved hypothetical protein 22.27 1 3 3 17 9.558E6 31.63 22.27 3 9 1238.93 9.24 2 8 238 25.1 3.93 HVO_2080 conserved hypothetical protein 22.22 1 6 7 103 1.898E8 176.13 14.81 6 51 7143.01 22.22 7 52 540 57.0 4.30 HVO_1387 enoyl-CoA hydratase 22.18 1 5 5 60 2.622E7 31.91 22.18 5 30 2368.57 22.18 5 30 257 27.5 4.51 HVO_1571 DNA topoisomerase VI subunit B 22.06 1 14 14 92 6.003E7 100.22 19.67 13 45 5191.33 19.67 12 47 798 87.4 4.73 HVO_1914 acetyl-CoA C-acyltransferase 22.02 1 6 6 36 2.432E7 31.23 19.36 5 16 1650.23 22.02 6 20 377 39.9 4.41 HVO_2533 conserved hypothetical protein 22.02 1 5 5 40 3.242E7 62.82 22.02 5 21 2242.79 22.02 5 19 336 35.1 4.39 HVO_0914 probable lyase (homolog to lactoylglutathione lyase) 22.01 1 5 5 25 2.048E7 16.20 18.15 4 9 1096.32 22.01 5 16 259 29.9 4.36 HVO_0206 alanine--tRNA ligase 21.80 1 15 15 148 2.954E7 173.05 18.55 13 72 8466.62 21.80 15 76 922 102.4 4.54 HVO_0048 argininosuccinate lyase 21.72 1 7 7 95 1.698E7 135.76 21.72 7 49 5404.62 21.72 7 46 488 50.8 4.53 HVO_2150 halocyanin 21.72 1 4 4 64 1.819E7 72.76 21.72 4 32 3323.26 21.72 4 32 373 37.7 4.42 HVO_0549 2-keto-3-deoxygluconate kinase 21.56 1 5 5 36 2.530E7 55.40 21.56 5 18 2438.51 21.56 5 18 320 34.1 4.34 HVO_1134 conserved hypothetical protein 21.53 1 10 10 82 2.913E7 53.07 21.53 10 41 3079.61 21.53 10 41 757 80.6 4.35 HVO_B0057 precorrin-3B C17-methyltransferase 21.51 1 4 4 47 1.006E7 66.06 21.51 4 24 2947.96 21.51 4 23 344 36.3 4.31 HVO_2020 DUF502 family protein 21.35 1 4 4 20 1.171E7 27.65 21.35 4 10 1501.73 21.35 4 10 267 29.4 4.35 47132620 keratin 2a [Homo sapiens] 21.28 1 8 12 93 1.529E8 119.24 19.87 11 46 6534.89 21.28 12 47 639 65.4 8.00 HVO_1545 dihydroxyacetone kinase subunit DhaL 21.12 1 4 4 23 1.320E7 21.58 21.12 4 11 913.17 21.12 4 12 232 24.8 4.48 HVO_1907 arNOG05511 family protein (AAA-type ATPase core domain protein) 21.10 1 7 7 20 9.926E6 20.78 16.67 6 11 840.36 16.03 6 9 474 53.4 4.59 HVO_B0292 ABC-type transport system periplasmic substrate-binding protein (probable substrate glycerol-3-phosphate) 21.06 1 8 8 40 1.384E7 54.82 19.84 7 20 2191.37 17.18 7 20 489 52.6 4.36 HVO_2315 "tritrans,polycis-undecaprenyl-diphosphate synthase" 21.04 1 6 6 50 1.067E7 49.47 19.42 5 24 2216.77 21.04 6 26 309 35.1 4.98 HVO_1291 fumarylacetoacetase family protein 20.99 1 3 3 26 9.854E7 17.15 20.99 3 13 961.13 20.99 3 13 243 26.3 4.55 HVO_1444 3-hydroxyacyl-CoA dehydrogenase 20.98 1 5 5 34 6.593E6 33.28 20.98 5 17 1779.60 20.98 5 17 286 30.8 4.46 HVO_2800 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 20.95 1 4 4 70 1.915E7 95.14 14.23 3 33 4653.44 20.95 4 37 253 27.6 4.42 HVO_1504 3-isopropylmalate dehydratase large subunit 20.93 1 8 8 66 7.471E7 92.72 19.24 7 33 4298.58 19.45 7 33 473 51.6 4.55 HVO_B0115 fumarylacetoacetase family protein 20.85 1 3 3 34 6.207E7 43.57 20.85 3 17 1097.29 20.85 3 17 283 30.3 4.21 HVO_2749 50S ribosomal protein L21e 20.83 1 2 2 10 1.859E6 9.55 20.83 2 5 388.60 20.83 2 5 96 10.6 10.95 HVO_1176 conserved hypothetical protein 20.72 1 3 4 10 1.122E7 3.77 16.73 3 4 358.19 20.72 4 6 251 27.7 5.11 HVO_0639 AAA-type ATPase (MoxR subfamily) 20.57 1 6 6 27 1.422E7 30.79 18.35 5 12 1334.21 20.57 6 15 316 34.7 4.89 HVO_1300 triosephosphate isomerase 20.56 1 4 4 51 1.153E8 66.82 20.56 4 25 3608.59 20.56 4 26 214 21.3 4.26 HVO_2456 anthranilate phosphoribosyltransferase 20.54 1 4 4 32 2.043E7 47.14 20.54 4 17 1035.33 18.73 3 15 331 33.8 4.35 HVO_B0149 oleate hydratase 20.45 1 7 8 40 1.928E7 28.08 14.07 6 17 2025.07 20.45 8 23 533 60.1 4.64 HVO_1181 transcription regulator (homolog to phosphate uptake regulator) 20.41 1 5 5 17 1.326E7 20.27 15.45 4 8 731.66 20.41 5 9 343 38.4 4.94 HVO_1257 AAA-type ATPase (MoxR subfamily) 20.41 1 5 5 40 4.449E6 47.28 17.46 4 19 2320.40 20.41 5 21 338 37.4 4.67 HVO_0534 ABC-type transport system ATP-binding protein (probable substrate sugar) 20.37 1 4 5 56 1.481E7 45.23 20.37 5 28 2726.43 20.37 5 28 383 41.9 4.21 HVO_C0069 GFO family oxidoreductase 20.37 1 4 4 22 6.825E6 5.88 20.37 4 11 649.37 20.37 4 11 324 36.0 5.10 HVO_0845 conserved hypothetical protein 20.29 1 3 3 20 4.558E6 30.84 20.29 3 10 1233.83 20.29 3 10 276 30.0 4.16 HVO_1370 gamma-glutamyl phosphate reductase 20.27 1 8 8 69 2.910E7 84.67 20.27 8 35 3483.08 20.27 8 34 444 48.1 4.34 HVO_2943 dihydroorotate dehydrogenase (quinone) 20.23 1 5 5 37 1.358E7 50.74 20.23 5 19 2146.70 17.38 4 18 351 37.4 4.72 HVO_1613 "probable glycosyltransferase, type 2" 20.18 1 4 4 16 2.565E7 19.30 20.18 4 8 1035.83 20.18 4 8 228 25.1 4.79 HVO_0452 leucine--tRNA ligase 20.15 1 12 12 79 1.749E7 108.40 20.15 12 39 4674.24 16.18 11 40 958 109.5 4.37 HVO_1563 conserved hypothetical protein 20.00 1 2 3 23 1.697E7 22.07 20.00 3 11 1241.79 20.00 3 12 125 13.8 11.02 HVO_1000 acyl-CoA synthetase (homolog to acetate--CoA ligase (ADP-forming)) 19.94 1 11 12 115 7.269E7 110.01 18.36 11 57 6041.03 19.94 12 58 697 74.5 4.13 HVO_A0339 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 19.93 1 7 7 78 2.938E7 107.17 19.93 7 40 4207.06 19.93 7 38 557 61.2 4.39 HVO_0417 metal-dependent carboxypeptidase 19.92 1 7 7 43 2.196E7 22.60 11.16 5 18 2160.14 19.92 7 25 502 57.3 4.42 HVO_B0118 SMC-like protein Sph2 19.72 1 11 11 100 3.810E7 79.62 19.72 11 49 4367.60 19.72 11 51 644 73.8 4.41 HVO_0530 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 19.69 1 5 5 146 7.875E7 209.19 19.69 5 76 8319.67 19.69 5 70 457 48.1 4.11 HVO_0982 NADH dehydrogenase-like complex subunit I 19.61 1 2 2 14 3.358E7 20.65 19.61 2 7 800.57 19.61 2 7 153 17.7 4.88 HVO_A0432 conserved hypothetical protein 19.51 1 0 5 38 9.252E6 66.29 19.51 5 19 3152.80 19.51 5 19 405 44.5 5.24 HVO_A0406 conserved hypothetical protein 19.51 1 0 5 38 9.252E6 66.29 19.51 5 19 3152.80 19.51 5 19 405 44.4 5.30 HVO_1579 uridine phosphorylase 19.49 1 2 2 3 6.402E6 6.76 19.49 2 3 272 29.0 4.64 HVO_1412 diphosphomevalonate decarboxylase 19.44 1 6 6 74 9.634E7 61.65 19.44 6 37 3687.58 19.44 6 37 324 35.4 4.78 HVO_1494 "fructose-1,6-bisphosphate aldolase, class II" 19.39 1 4 4 26 1.572E7 27.88 19.39 4 13 1228.81 19.39 4 13 330 36.3 4.35 HVO_0024 thiosulfate sulfurtransferase 19.38 1 3 3 8 1.447E7 10.35 19.38 3 4 279.58 19.38 3 4 258 28.4 4.30 HVO_0055 CBS domain protein 19.37 1 4 4 31 2.254E7 20.69 19.37 4 15 1849.76 19.37 4 16 284 30.8 4.27 HVO_1380 methylmalonyl-CoA mutase subunit A 19.35 1 6 6 35 1.145E7 39.73 19.35 6 17 1409.08 19.35 6 18 558 61.9 4.41 HVO_A0627 conserved hypothetical protein 19.21 1 5 5 23 2.663E7 22.12 19.21 5 11 776.86 19.21 5 12 354 38.1 4.70 HVO_B0228 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 19.17 1 5 5 27 6.451E6 36.08 19.17 5 14 1123.77 14.38 4 13 459 50.2 4.36 HVO_0209 acyl-CoA dehydrogenase 19.12 1 6 6 16 4.011E6 20.30 19.12 6 8 586.79 19.12 6 8 387 42.4 4.93 HVO_A0619 conserved hypothetical protein 19.03 1 7 7 32 6.365E6 23.24 19.03 7 16 1359.21 19.03 7 16 452 48.2 4.68 HVO_2528 phytoene dehydrogenase (phytoene desaturase) 19.00 1 11 11 91 4.241E7 74.41 19.00 11 46 3366.08 19.00 11 45 500 55.8 4.56 HVO_B0050 ATP-dependent cobaltochelatase subunit CobN 19.00 1 19 19 148 3.862E7 157.22 16.98 17 74 6423.12 19.00 19 74 1284 141.2 4.35 HVO_0944 ba3-type terminal oxidase subunit II 18.99 1 3 3 42 4.258E7 56.10 18.99 3 20 2527.41 18.99 3 22 179 19.4 4.28 HVO_1395 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 18.97 1 6 6 33 4.278E7 26.73 18.97 6 17 1224.46 18.97 6 16 427 45.4 4.56 HVO_B0371 aldehyde dehydrogenase 18.95 1 4 4 37 2.908E7 62.93 18.95 4 18 2427.27 18.95 4 19 496 52.5 4.39 HVO_1289 OsmC domain protein 18.94 1 2 2 62 6.544E6 108.59 18.94 2 31 5497.44 18.94 2 31 132 14.2 3.85 HVO_1957 proteasome-activating nucleotidase 18.93 1 3 6 13 9.748E5 7.50 18.93 6 8 378.24 6.80 3 5 412 45.6 4.48 HVO_1649 methionine adenosyltransferase 18.91 1 4 4 26 2.296E7 33.81 18.91 4 14 883.51 18.91 4 12 402 43.5 4.45 HVO_1573 DNA gyrase subunit A 18.79 1 13 13 88 4.448E7 85.97 15.31 10 42 3705.25 18.79 13 46 862 94.8 4.56 HVO_0565 ABC-type transport system ATP-binding protein (probable substrate maltose) 18.73 1 5 5 10 6.663E5 4.18 16.36 4 4 315.16 18.73 5 6 379 41.7 4.83 HVO_B0059 cobalt-precorrin 5A hydrolase 18.71 1 3 3 23 1.220E7 33.48 8.90 2 11 995.59 18.71 3 12 326 34.5 4.51 HVO_1085 phosphoribosylglycinamide formyltransferase / phosphoribosylaminoimidazolecarboxamide formyltransferase 18.67 1 6 6 27 3.158E7 38.32 18.67 6 13 1324.07 18.67 6 14 525 56.4 4.40 HVO_2981 uracil phosphoribosyltransferase 18.58 1 3 3 14 4.924E6 11.93 11.06 2 5 834.04 18.58 3 9 226 24.5 4.49 HVO_2375 ABC-type transport system periplasmic substrate-binding protein (probable substrate phosphate) 18.55 1 4 4 115 1.664E8 115.57 18.55 4 57 4885.89 18.55 4 58 345 37.0 3.95 HVO_0161 ATP phosphoribosyltransferase 18.51 1 4 4 18 5.627E6 13.49 18.51 4 8 850.21 18.51 4 10 281 30.4 4.60 HVO_1707 ABC-type transport system ATP-binding protein (probable substrate iron-III) 18.51 1 3 4 11 1.396E7 6.04 18.51 4 5 390.55 18.51 4 6 389 41.9 4.40 HVO_2169 conserved hypothetical protein 18.50 1 5 5 31 3.299E7 28.08 18.50 5 16 1279.24 18.50 5 15 346 36.5 4.39 HVO_2419 hydroxymethylglutaryl-CoA synthase 18.20 1 6 6 27 1.489E7 31.98 18.20 6 13 1413.33 15.51 5 14 445 50.1 4.64 HVO_1287 PfpI family protease 18.18 1 2 2 8 2.542E6 7.66 18.18 2 4 245.05 18.18 2 4 198 21.5 4.53 HVO_1576 NAD-dependent epimerase/dehydratase 17.97 1 1 4 27 1.177E7 18.86 17.97 4 14 1094.75 13.73 3 13 306 33.9 4.51 HVO_B0082 ABC-type transport system periplasmic substrate-binding protein (probable substrate dipeptide/oligopeptide) 17.93 1 8 8 36 1.210E7 46.53 17.93 8 18 2149.15 17.93 8 18 569 62.8 4.30 HVO_0011 "inosine-5'-monophosphate cyclohydrolase, archaeal-type" 17.89 1 3 3 27 4.079E7 29.16 17.89 3 13 1339.56 17.89 3 14 190 20.6 4.30 HVO_2630 conserved hypothetical protein 17.88 1 4 4 16 2.750E6 20.58 17.88 4 8 750.43 17.88 4 8 302 32.9 4.48 HVO_2068 "FtsZ family protein, type III" 17.84 1 4 4 11 1.371E7 10.57 17.84 4 5 570.01 17.84 4 6 370 38.7 4.49 HVO_A0491 ABC-type transport system ATP-binding protein (probable substrate sugar) 17.75 1 4 4 14 1.662E6 20.84 17.75 4 8 381.95 17.75 4 6 383 41.1 4.48 HVO_1129 conserved hypothetical protein 17.69 1 4 5 17 8.869E6 20.99 16.41 4 8 867.63 17.69 5 9 390 43.0 4.44 HVO_0054 glycine--tRNA ligase 17.68 1 7 7 36 6.244E7 57.05 15.32 6 18 2563.81 15.32 6 18 594 64.9 4.21 HVO_0123 signal recognition particle 54K protein 17.63 1 7 7 66 4.647E7 70.05 15.48 6 32 3434.36 17.63 7 34 465 50.9 4.50 HVO_2998 homoserine O-acetyltransferase 17.59 1 3 3 14 1.557E7 16.88 17.59 3 7 690.72 17.59 3 7 415 44.8 4.69 HVO_1976 protein-export membrane protein SecD 17.56 1 5 5 20 1.786E7 32.01 17.56 5 10 1071.46 17.56 5 10 524 55.0 4.51 HVO_0721 PHP domain protein 17.32 1 2 2 7 8.524E6 3.61 17.32 2 3 262.50 17.32 2 4 254 28.2 5.97 HVO_1346 GTP-binding protein HflX 17.32 1 6 6 47 4.051E7 47.89 17.32 6 23 2732.83 17.32 6 24 433 48.2 4.73 HVO_2496 adenylate kinase 17.31 1 3 3 14 1.061E7 13.96 17.31 3 7 797.11 17.31 3 7 208 23.1 4.25 HVO_B0194 conserved hypothetical protein 17.26 1 5 6 25 2.074E7 21.86 17.26 6 12 1056.80 17.26 6 13 394 42.7 5.35 HVO_2801 ABC-type transport system ATP-binding protein (probable substrate branched-chain amino acids) 17.07 1 3 3 38 2.633E7 48.75 17.07 3 19 2192.16 17.07 3 19 287 31.4 4.48 HVO_1593 PAC2 family protein 16.94 1 2 2 6 7.020E6 10.85 16.94 2 3 431.90 16.94 2 3 248 26.6 4.46 HVO_1609 conserved hypothetical protein 16.90 1 4 4 39 6.890E7 66.22 16.90 4 19 2952.83 16.90 4 20 290 31.0 4.58 HVO_2323 DUF3311 family protein 16.90 1 2 2 2 1.718E5 92.21 16.90 2 2 71 8.4 11.25 HVO_0304 electron transfer flavoprotein alpha subunit 16.72 1 3 3 16 4.879E6 17.27 13.56 2 6 734.74 16.72 3 10 317 33.5 4.18 HVO_0788 tryptophan synthase beta subunit 16.59 1 5 5 22 1.871E7 7.94 16.59 5 11 710.09 16.59 5 11 422 45.7 4.65 HVO_2467 NADPH:quinone reductase 16.51 1 4 4 22 4.259E6 26.26 16.51 4 11 1217.34 16.51 4 11 321 33.0 4.51 83405576 "Similar to Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16) [Homo sapiens]" 16.47 1 0 2 18 1.776E7 17.65 16.47 2 9 941.54 16.47 2 9 85 10.0 5.94 HVO_1523 agl cluster protein AglQ 16.44 1 4 4 18 9.764E6 20.44 16.44 4 9 720.10 16.44 4 9 371 42.1 6.04 HVO_0467 PhoU/TrkA-C domain protein 16.42 1 5 5 23 1.601E7 27.65 16.42 5 12 1137.25 12.94 4 11 402 43.3 4.49 HVO_1547 isoleucine--tRNA ligase 16.40 1 11 11 62 2.233E7 74.02 14.09 10 30 2879.73 16.40 11 32 1043 117.9 4.30 HVO_2072 S-layer glycoprotein 16.32 1 6 6 3024 2.640E9 4046.28 16.32 6 1508 152993.15 16.32 6 1516 827 85.1 3.65 HVO_1981 hypothetical protein 16.24 1 3 3 233 3.941E6 451.13 16.24 3 117 20266.14 16.24 3 116 197 20.3 4.01 HVO_2740 nucleoside-diphosphate kinase 16.23 1 2 2 16 5.425E6 20.95 16.23 2 8 800.39 16.23 2 8 154 17.5 4.50 HVO_2857 "probable inositol-1(or 4)-monophosphatase / fructose-1,6-bisphosphatase, archaeal-type" 16.23 1 3 3 8 5.130E6 5.24 16.23 3 4 262.50 16.23 3 4 265 28.7 4.87 HVO_1125 cysteine--tRNA ligase 16.19 1 6 6 17 5.323E6 22.36 14.98 5 8 768.28 16.19 6 9 494 55.2 4.56 HVO_0319 A-type ATP synthase subunit D 16.17 1 3 3 22 1.123E7 34.36 16.17 3 12 1174.51 16.17 3 10 235 26.7 4.72 HVO_2082 conserved hypothetical protein 15.91 1 3 3 48 3.933E7 69.38 15.91 3 24 2086.14 15.91 3 24 396 40.9 4.50 HVO_2916 probable oxidoreductase (short-chain dehydrogenase family) 15.87 1 3 3 62 2.172E7 109.84 15.87 3 31 4998.24 15.87 3 31 252 26.0 4.39 HVO_2781 DNA-directed RNA polymerase subunit D 15.83 1 4 4 29 4.454E7 38.00 15.83 4 14 1599.21 15.83 4 15 259 28.1 4.32 HVO_0331 proline dehydrogenase 15.77 1 4 4 12 1.305E7 9.46 15.77 4 6 387.39 15.77 4 6 279 30.9 4.68 HVO_3012 origin-associated protein OapC 15.76 1 2 2 8 1.002E6 2.60 15.76 2 4 237.15 15.76 2 4 330 34.5 4.34 HVO_A0288 probable oxidoreductase (short-chain dehydrogenase family) 15.71 1 3 3 9 3.842E7 7.05 15.71 3 5 332.07 9.29 2 4 280 29.9 4.74 HVO_1760 ABC-type transport system ATP-binding protein (probable substrate iron-III) 15.70 1 3 4 34 8.560E6 35.94 15.70 4 17 1630.75 15.70 4 17 293 32.4 4.58 HVO_1589 molecular chaperone DnaJ 15.58 1 5 5 30 9.327E6 16.75 8.83 3 13 1550.18 15.58 5 17 385 41.9 4.97 HVO_1165 mechanosensitive channel protein MscS 15.56 1 4 4 30 2.591E7 40.74 15.56 4 15 1359.63 15.56 4 15 302 32.6 4.91 HVO_1031 thioredoxin-disulfide reductase 15.50 1 4 4 9 7.724E6 10.58 10.82 3 4 415.88 15.50 4 5 342 37.4 4.46 HVO_B0039 alpha-ketoglutarate semialdehyde dehydrogenase 15.35 1 6 6 18 4.253E6 9.68 15.35 6 9 630.13 15.35 6 9 482 50.6 4.31 HVO_1503 3-isopropylmalate dehydratase small subunit 15.35 1 2 2 6 1.901E7 599.35 15.35 2 6 202 22.0 4.15 HVO_0697 PAC2 family protein 15.29 1 2 2 10 1.037E7 19.03 15.29 2 5 789.84 15.29 2 5 255 27.4 4.08 HVO_2122 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 15.22 1 4 5 36 3.088E7 36.75 11.68 4 15 2324.75 15.22 5 21 368 40.0 4.63 HVO_0358 homoserine dehydrogenase 15.14 1 3 4 38 1.043E8 42.07 15.14 4 19 1903.67 15.14 4 19 317 32.4 4.44 HVO_0519 replication protein A 14.91 1 6 6 39 2.591E6 37.74 12.01 5 19 1552.17 14.91 6 20 483 51.0 4.13 HVO_1985 ABC-type transport system ATP-binding protein 14.83 1 3 3 36 2.539E7 34.75 14.83 3 18 1351.16 14.83 3 18 317 35.0 4.54 HVO_1101 4-hydroxy-tetrahydrodipicolinate synthase 14.75 1 4 4 24 9.869E6 31.73 14.75 4 12 1509.91 14.75 4 12 305 32.7 4.56 HVO_1014 cox-type terminal oxidase subunit II 14.68 1 2 2 130 1.281E8 170.40 14.68 2 65 6543.69 14.68 2 65 252 27.7 4.59 HVO_1477 endonuclease domain protein 14.68 1 3 3 22 1.794E7 30.50 14.68 3 11 1116.69 14.68 3 11 327 34.1 4.32 HVO_2639 DUF1611 family protein 14.66 1 2 2 2 0.000E0 70.84 14.66 2 2 341 36.3 4.44 13432173 "Keratin, type I cytoskeletal 14 (Cytokeratin-14) (CK-14) (Keratin-14) (K14)" 14.62 1 1 7 56 1.424E7 71.31 14.62 7 28 3091.06 14.62 7 28 472 51.6 5.16 HVO_2549 30S ribosomal protein S8 14.62 1 2 2 16 1.233E7 16.68 14.62 2 8 554.27 14.62 2 8 130 14.1 4.79 HVO_A0003 ParA domain protein 14.60 1 3 3 18 9.059E6 25.40 14.60 3 9 893.90 14.60 3 9 274 30.3 4.53 HVO_0739 conserved hypothetical protein 14.59 1 3 3 27 1.571E7 30.74 14.59 3 14 1607.55 14.59 3 13 329 33.5 4.97 HVO_1469 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase 14.55 1 5 6 36 1.308E7 28.17 14.55 6 18 1693.16 13.87 5 18 584 63.3 4.79 HVO_1008 GFO family oxidoreductase 14.46 1 3 3 17 2.178E7 21.14 14.46 3 9 853.61 7.83 2 8 332 36.0 4.72 HVO_2871 pyridoxal phosphate-dependent aminotransferase 14.44 1 5 5 26 9.750E6 39.89 14.44 5 13 1515.01 14.44 5 13 450 49.1 4.70 HVO_0893 methylmalonyl-CoA mutase subunit A 14.31 1 5 5 30 2.220E7 43.12 14.31 5 15 1229.25 14.31 5 15 566 63.1 4.36 HVO_2156 UspA domain protein 14.29 1 3 3 19 8.918E6 33.55 14.29 3 10 1418.76 14.29 3 9 301 31.6 4.69 HVO_1880 conserved hypothetical protein 14.22 1 1 3 5 2.903E5 4.82 12.44 2 2 134.04 14.22 3 3 225 23.8 4.59 HVO_1054 aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A 14.18 1 5 5 29 5.138E6 47.73 14.18 5 15 1507.14 14.18 5 14 423 43.9 4.31 HVO_0242 aminopeptidase (homolog to leucyl aminopeptidase / aminopeptidase T) 14.17 1 5 5 45 1.895E7 45.51 14.17 5 23 2204.68 12.50 4 22 360 39.5 4.31 HVO_1878 NAD synthase 14.13 1 4 4 24 7.649E6 24.39 14.13 4 12 1128.54 14.13 4 12 276 29.6 4.37 HVO_2725 bifunctional short chain isoprenyl diphosphate synthase 14.08 1 4 4 26 1.709E7 33.88 14.08 4 13 1460.80 14.08 4 13 348 38.2 4.32 HVO_0424 ABC-type transport system ATP-binding protein 14.07 1 5 5 14 9.547E6 15.87 8.11 4 6 504.52 14.07 5 8 604 67.2 4.49 HVO_A0494 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 14.00 1 3 3 62 5.596E7 76.69 14.00 3 31 3617.48 14.00 3 31 443 47.8 4.21 HVO_2340 amine oxidase family protein 13.96 1 4 4 32 1.724E7 26.77 13.96 4 14 1500.40 13.96 4 18 437 48.7 4.44 HVO_B0153 CapB domain protein 13.92 1 7 7 34 1.812E7 26.58 13.92 7 15 1576.05 13.92 7 19 546 60.7 4.87 HVO_1610 conserved hypothetical protein 13.78 1 2 2 5 2.268E6 5.73 13.78 2 3 182.03 13.78 2 2 283 30.5 4.55 HVO_B0071 oxidoreductase (homolog to zinc-containing alcohol dehydrogenase) 13.75 1 4 4 14 3.141E7 18.76 13.75 4 7 725.44 13.75 4 7 349 37.0 4.70 HVO_2798 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 13.73 1 4 4 260 7.322E8 294.94 13.73 4 132 13513.48 13.73 4 128 437 44.6 3.95 HVO_2707 GFO family oxidoreductase 13.71 1 4 4 24 4.887E7 29.83 13.71 4 12 1330.44 13.71 4 12 372 41.0 4.55 HVO_1172 NAD-dependent epimerase/dehydratase 13.65 1 4 4 38 3.189E7 51.01 13.65 4 18 1887.59 13.65 4 20 315 34.9 4.34 HVO_2031 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 13.65 1 2 2 43 6.501E7 87.53 13.65 2 21 4080.52 13.65 2 22 403 42.4 3.99 HVO_2203 conserved hypothetical protein 13.64 1 2 3 31 4.464E7 25.51 13.64 3 16 1396.39 13.64 3 15 264 28.4 4.20 HVO_2670 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 13.52 1 10 12 84 2.680E7 105.49 13.52 12 41 5128.09 13.52 12 43 1058 113.8 4.69 HVO_C0001 Orc1-type DNA replication protein 13.48 1 2 2 3 6.856E6 0.00 13.48 2 3 408 45.2 4.97 HVO_1354 DNA mismatch repair protein MutS 13.45 1 6 6 40 1.747E7 47.96 13.45 6 20 1562.98 13.45 6 20 580 62.1 4.56 HVO_0965 "AMP phosphorylase (ribose-1,5-bisphosphate forming)" 13.41 1 5 5 18 8.216E6 15.14 11.38 4 9 792.88 13.41 5 9 492 52.1 4.83 HVO_2700 AAA-type ATPase (CDC48 subfamily) 13.40 1 6 7 35 7.908E6 32.79 13.40 7 17 1300.39 13.40 7 18 754 82.8 4.75 HVO_0818 threonine synthase 13.37 1 4 4 23 6.619E6 23.62 13.37 4 12 860.12 9.25 3 11 389 40.8 4.31 HVO_2958 2-oxo-3-methylvalerate dehydrogenase E1 component alpha subunit 13.32 1 3 3 5 1.173E7 2.53 10.60 2 2 182.84 13.32 3 3 368 40.9 4.68 HVO_2379 transcription regulator (homolog to phosphate uptake regulator) 13.27 1 3 3 26 1.544E7 20.51 13.27 3 13 1178.31 13.27 3 13 226 25.5 4.25 HVO_2130 IclR family transcription regulator 13.24 1 3 3 8 1.440E6 2.40 9.19 2 3 230.30 13.24 3 5 272 30.1 5.55 HVO_0469 AstE family protein 13.21 1 3 3 17 1.043E7 23.61 13.21 3 9 1045.69 13.21 3 8 318 33.9 5.85 HVO_1097 diaminopimelate epimerase 13.19 1 2 2 2 8.463E5 0.00 13.19 2 2 288 29.9 4.48 HVO_1094 ribonuclease P protein component 3 12.99 1 2 2 10 8.592E6 8.07 12.99 2 5 299.13 12.99 2 5 231 25.6 5.31 HVO_1496 phosphotransferase system component I 12.92 1 5 5 21 3.421E6 30.43 12.92 5 11 1008.79 10.97 4 10 565 60.3 4.21 HVO_B0164 respiratory nitrate reductase catalytic subunit 12.92 1 5 5 6 3.357E6 0.00 6.10 2 2 44.27 10.27 4 4 983 111.1 4.61 HVO_1558 cytochrome P450 12.90 1 5 5 27 9.929E6 35.10 10.60 4 13 1341.61 12.90 5 14 434 48.4 4.92 HVO_1168 "probable glycosyltransferase, type 1" 12.75 1 4 4 30 4.615E6 37.51 12.75 4 15 1648.32 12.75 4 15 353 39.1 5.01 HVO_2160 conserved hypothetical protein 12.67 1 19 20 578 1.133E9 887.20 12.67 20 293 37964.34 12.67 20 285 2257 232.7 3.92 HVO_1268 conserved hypothetical protein 12.66 1 2 2 4 0.000E0 3.59 12.66 2 2 150.37 12.66 2 2 237 26.4 5.21 HVO_0419 peptidase M20 family protein 12.64 1 2 2 6 5.321E6 275.91 12.64 2 6 364 38.4 4.44 HVO_1140 acyl-CoA dehydrogenase 12.63 1 4 4 34 5.137E7 43.48 12.63 4 17 1782.73 12.63 4 17 380 41.2 4.55 HVO_0763 YphA family protein 12.57 1 2 2 10 1.201E7 1151.62 12.57 2 10 175 18.9 6.54 HVO_2648 phosphoglycerate dehydrogenase 12.54 1 3 3 16 3.091E7 24.70 12.54 3 8 1222.68 12.54 3 8 319 34.2 4.64 HVO_2161 conserved hypothetical protein 12.53 1 2 2 49 5.074E8 83.78 12.53 2 24 3041.78 12.53 2 25 359 36.7 3.88 HVO_1510 2-isopropylmalate synthase 12.50 1 4 4 17 1.495E7 22.11 12.50 4 9 812.64 12.50 4 8 440 47.7 4.82 HVO_B0101 IclR family transcription regulator 12.45 1 3 3 28 4.955E6 26.38 12.45 3 14 1258.48 12.45 3 14 257 28.6 5.02 HVO_1751 P-type transport ATPase (probable substrate copper/metal cation) 12.43 1 7 7 41 4.551E7 57.98 11.38 6 20 2613.29 12.43 7 21 861 89.9 4.40 HVO_1368 probable metallo-beta-lactamase family hydrolase 12.36 1 3 3 20 8.871E6 24.51 8.61 2 9 971.43 12.36 3 11 267 29.3 4.49 1346347 "Keratin, type II cytoskeletal 6D (Cytokeratin-6D) (CK 6D) (K6d keratin)" 12.24 1 0 5 55 1.463E7 42.24 5.73 3 26 3005.08 12.24 5 29 384 42.4 5.40 HVO_A0611 ABC-type transport system periplasmic substrate-binding protein (probable substrate zinc) 12.24 1 3 3 21 1.369E7 9.60 12.24 3 11 662.88 12.24 3 10 335 35.9 4.39 HVO_0724 ArsA family ATPase 12.22 1 4 4 25 2.490E7 24.76 12.22 4 12 1285.54 12.22 4 13 409 43.9 4.22 HVO_2454 anthranilate synthase component I 12.21 1 4 4 8 3.896E6 10.52 12.21 4 4 415.51 12.21 4 4 524 55.9 4.56 HVO_B0233 alpha-L-arabinofuranosidase 12.13 1 4 4 18 4.169E6 25.45 12.13 4 10 878.82 6.26 3 8 511 57.5 4.39 HVO_2427 replication factor C large subunit 12.09 1 5 5 25 1.531E7 28.28 12.09 5 13 1501.53 9.43 4 12 488 53.4 4.67 HVO_2167 conserved hypothetical protein 11.88 1 2 2 6 4.765E6 5.64 11.88 2 3 256.55 11.88 2 3 303 31.8 5.12 HVO_2999 O-acetylhomoserine aminocarboxypropyltransferase (methionine synthase) 11.85 1 3 3 6 1.838E6 2.11 5.01 2 3 105.39 11.85 3 3 439 47.2 4.59 HVO_A0425 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 11.85 1 3 4 9 3.705E6 7.17 11.85 4 5 344.89 11.85 4 4 346 38.4 5.24 HVO_1819 conserved hypothetical protein 11.79 1 2 2 15 9.057E7 7.82 11.79 2 15 229 25.5 4.25 HVO_2882 DUF4013 family protein 11.67 1 2 2 15 4.227E7 5.67 11.67 2 7 701.41 11.67 2 8 240 25.4 4.55 HVO_A0452 UspA domain protein 11.60 1 2 2 2 1.558E6 180.50 11.60 2 2 293 31.3 4.63 HVO_B0058 precorrin-3B C17-methyltransferase 11.56 1 2 2 12 3.796E6 15.60 11.56 2 6 395.87 11.56 2 6 294 31.8 4.40 HVO_1110 ABC-type transport system periplasmic substrate-binding protein (probable substrate cobalamin) 11.52 1 3 3 55 6.312E7 70.98 11.52 3 28 3066.64 11.52 3 27 382 39.6 4.25 HVO_1264 conserved hypothetical protein 11.52 1 2 2 7 4.346E6 7.65 11.52 2 4 403.94 11.52 2 3 217 23.4 4.22 HVO_2703 3-methyl-2-oxobutanoate hydroxymethyltransferase 11.52 1 2 2 16 3.385E7 7.07 11.52 2 8 491.46 11.52 2 8 269 28.3 4.49 HVO_0950 "2-dehydro-3-deoxy-phosphogluconate aldolase, bacterial-type" 11.42 1 2 2 15 3.497E6 9.01 11.42 2 8 364.57 11.42 2 7 219 22.4 4.06 HVO_1513 conserved hypothetical protein 11.40 1 2 2 8 4.167E7 11.96 11.40 2 4 405.90 11.40 2 4 228 25.1 5.07 HVO_0175 DNA polymerase sliding clamp 11.34 1 3 3 26 7.764E6 22.96 11.34 3 13 1245.24 11.34 3 13 247 26.7 4.39 HVO_1963 translation initiation factor aIF-5B (bacterial-type IF2) 11.33 1 3 3 9 4.805E6 15.86 6.17 2 4 786.00 11.33 3 5 600 65.3 4.68 HVO_2650 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 11.28 1 5 5 16 6.640E6 10.47 11.28 5 8 731.69 11.28 5 8 461 50.7 4.73 HVO_0250 DUF21/CBS domain protein 11.25 1 4 4 10 5.969E6 16.41 11.25 4 6 356.30 7.43 3 4 471 51.7 4.28 HVO_2590 probable oxidoreductase (short-chain dehydrogenase family) 11.25 1 3 3 7 7.647E6 6.83 6.75 2 3 309.06 11.25 3 4 311 33.6 4.89 HVO_0792 3-dehydroquinate synthase type II 11.22 1 3 3 6 3.562E6 8.17 8.42 2 3 155.35 5.87 2 3 392 43.1 4.44 HVO_0552 DNA mismatch repair protein MutS 11.15 1 8 8 42 1.929E7 45.27 11.15 8 21 1699.43 11.15 8 21 924 99.2 4.65 HVO_2081 pectin lyase domain protein 11.14 1 9 9 40 2.287E6 49.27 11.14 9 20 2371.36 11.14 9 20 1041 109.7 5.34 HVO_0020 ABC-type transport system ATP-binding protein (probable substrate thiamine) 11.08 1 2 3 16 3.596E6 19.94 11.08 3 8 855.89 11.08 3 8 361 38.3 4.79 HVO_C0054 hypothetical protein 11.05 1 2 2 18 5.007E6 36.79 11.05 2 9 2008.39 11.05 2 9 344 37.5 4.70 HVO_A0496 UspA domain protein 11.03 1 3 3 19 2.937E6 18.95 6.55 2 9 728.44 11.03 3 10 290 31.4 4.60 HVO_2961 dihydrolipoyl dehydrogenase 10.95 1 4 4 6 1.206E7 4.29 10.95 4 4 221.10 6.53 2 2 475 49.9 4.41 HVO_2048 "probable glycosyltransferase, type 1" 10.86 1 3 3 16 6.255E6 10.92 10.86 3 7 749.33 10.86 3 9 359 40.5 5.30 HVO_0745 "FtsZ family protein, type III" 10.83 1 3 3 24 1.050E7 30.55 10.83 3 12 1165.02 10.83 3 12 360 37.1 4.51 HVO_1073 ThiJ/PfpI family protein 10.71 1 2 2 3 2.247E6 9.13 10.71 2 3 224 23.9 4.12 HVO_A0426 ABC-type transport system ATP-binding protein (probable substrate dipeptide/oligopeptide) 10.68 1 3 3 13 5.513E6 21.43 10.68 3 7 745.21 7.42 2 6 337 36.8 5.16 HVO_0321 peptide chain release factor aRF-1 10.63 1 2 2 2 1.373E6 2.34 10.63 2 2 414 46.6 4.83 HVO_2671 aminotransferase class V (serine--pyruvate aminotransferase / alanine--glyoxylate aminotransferase) 10.63 1 3 3 12 2.653E7 0.00 7.09 2 5 406.74 10.63 3 7 395 42.4 4.54 HVO_2297 deoxyhypusine synthase 10.58 1 2 2 6 2.184E6 2.22 10.58 2 3 150.04 10.58 2 3 359 38.6 4.59 HVO_0396 FAD-dependent oxidoreductase (homolog to geranylgeranyl reductase) 10.56 1 3 3 4 1.352E6 2.57 10.56 3 4 360 39.2 5.01 HVO_0541 aconitate hydratase 10.55 1 8 8 34 1.191E7 36.29 10.55 8 18 1345.81 10.55 8 16 938 102.1 4.40 HVO_2510 GNAT family acetyltransferase 10.53 1 3 3 19 6.495E6 24.96 10.53 3 10 920.85 10.53 3 9 304 33.7 4.49 HVO_0165 5-methylthioadenosine/S-adenosylhomocysteine deaminase 10.47 1 3 3 14 1.817E7 19.44 10.47 3 7 844.69 10.47 3 7 430 45.1 4.50 547751 "Keratin, type I cytoskeletal 17 (Cytokeratin-17) (CK-17) (Keratin-17) (K17) (39.1)" 10.42 1 0 5 42 1.424E7 55.14 10.42 5 21 2310.12 10.42 5 21 432 48.1 5.02 HVO_1660 DisA-N domain protein 10.41 1 1 2 2 9.899E6 5.55 10.41 2 2 269 28.9 4.73 HVO_1601 ABC-type transport system ATP-binding protein (probable substrate sulfonate) 10.33 1 1 2 5 2.655E6 3.11 10.33 2 3 127.49 10.33 2 2 271 29.0 4.36 HVO_0968 NADH dehydrogenase-like complex subunit CD 10.28 1 0 7 221 1.072E9 312.09 10.28 7 110 16327.70 10.28 7 111 564 63.3 4.60 HVO_1388 conserved hypothetical protein 10.24 1 2 2 2 2.068E6 1.94 10.24 2 2 166 18.9 4.54 HVO_1916 Kef-type transport system (probable substrate potassium) 10.24 1 5 5 64 1.967E7 80.06 10.24 5 32 3685.21 10.24 5 32 635 66.2 4.63 HVO_2361 carbamoyl-phosphate synthase (glutamine-hydrolyzing) large subunit 10.07 1 11 11 89 3.624E7 121.67 10.07 11 45 5171.32 10.07 11 44 1082 117.2 4.32 HVO_A0550 receiver/sensor box histidine kinase 10.06 1 3 5 9 2.437E6 8.98 10.06 5 6 217.45 2.37 3 3 885 95.9 4.46 HVO_1572 DNA gyrase subunit B 10.02 1 6 6 27 9.891E6 24.71 8.29 5 13 1211.24 8.92 5 14 639 71.2 4.83 HVO_2945 valine--tRNA ligase 10.00 1 5 5 25 8.486E6 15.48 8.51 4 13 959.19 6.32 4 12 870 98.9 4.36 HVO_2501 alpha/beta hydrolase fold protein 9.81 1 2 2 4 1.597E7 9.70 9.81 2 4 316 35.3 5.72 HVO_1295 histidinol-phosphate aminotransferase 9.70 1 2 3 8 3.373E6 9.54 8.59 2 3 501.05 9.70 3 5 361 39.4 4.51 HVO_3006 UvrABC system protein C 9.50 1 2 2 2 1.634E5 2.00 9.50 2 2 579 64.3 5.19 HVO_1447 propionyl-CoA carboxylase carboxyltransferase component 9.47 1 4 4 20 8.046E6 28.38 9.47 4 10 848.41 9.47 4 10 581 63.6 4.70 HVO_0655 NAD-dependent epimerase/dehydratase 9.38 1 2 2 8 5.451E6 9.69 9.38 2 4 274.61 9.38 2 4 341 36.9 4.74 HVO_1604 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 9.38 1 4 4 33 2.128E7 34.20 9.38 4 17 1488.52 9.38 4 16 373 40.2 4.44 HVO_A0489 homolog to homocitrate synthase 9.37 1 2 2 2 0.000E0 1.77 9.37 2 2 363 38.1 4.44 HVO_2267 hypothetical protein 9.35 1 2 2 6 1.196E6 1.79 9.35 2 3 85.19 9.35 2 3 385 44.3 4.56 23503075 "Keratin, type I cytoskeletal 16 (Cytokeratin-16) (CK-16) (Keratin-16) (K16)" 9.30 1 1 5 41 1.236E7 46.98 7.61 4 20 2196.64 9.30 5 21 473 51.2 5.05 HVO_A0551 acyl-CoA synthetase 9.29 1 4 4 17 6.102E6 18.65 9.29 4 8 948.62 9.29 4 9 538 59.6 4.65 HVO_A0180 SMC-like protein Sph1 9.27 1 2 3 7 4.931E6 0.00 8.43 2 3 256.36 3.71 2 4 593 66.4 4.58 HVO_A0271 glycerol-3-phosphate dehydrogenase subunit C 9.21 1 1 2 4 4.038E7 249.96 9.21 2 4 478 53.1 4.74 HVO_2172 conserved hypothetical protein 9.18 1 4 4 14 9.022E6 28.21 9.18 4 7 1108.75 9.18 4 7 741 75.2 4.27 HVO_1654 cysteine synthase 9.15 1 2 2 2 1.386E7 168.73 9.15 2 2 306 32.3 4.32 HVO_1048 phosphoribosylformylglycinamidine synthase 2 9.12 1 5 5 21 1.772E7 35.54 9.12 5 10 1572.98 9.12 5 11 702 72.9 4.18 HVO_A0283 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 9.11 1 4 4 24 1.442E7 20.08 9.11 4 12 977.82 9.11 4 12 450 49.1 4.51 HVO_0145 replication factor C small subunit 9.09 1 2 2 8 6.653E6 10.16 9.09 2 4 336.24 9.09 2 4 341 37.8 4.93 HVO_1983 malate synthase 9.01 1 2 2 4 9.853E5 1.85 9.01 2 2 74.81 9.01 2 2 433 48.0 4.42 HVO_0997 peptidase M24 family protein 8.97 1 2 2 4 6.686E6 5.23 8.97 2 2 172.91 8.97 2 2 368 39.9 4.49 HVO_2790 ATP-binding protein Mrp 8.96 1 2 2 7 1.391E7 748.58 8.96 2 7 346 36.8 4.50 HVO_0421 arNOG04375 family protein (homolog to PilT-type ATPase) 8.95 1 3 3 15 0.000E0 8.10 8.95 3 8 298.86 8.95 3 7 626 67.6 4.65 HVO_1517 dolichyl-phosphate hexosyltransferase AglJ 8.91 1 2 2 18 1.879E7 0.00 8.91 2 9 571.63 8.91 2 9 303 33.2 4.82 HVO_2726 glutamate--tRNA ligase 8.89 1 3 3 9 5.360E6 7.41 8.89 3 4 265.89 8.89 3 5 585 65.2 4.58 HVO_2692 ABC-type transport system ATP-binding protein (probable substrate sugar) 8.86 1 1 3 6 4.943E6 7.06 8.86 3 3 367.60 8.86 3 3 395 43.3 4.37 HVO_0787 indole-3-glycerol-phosphate synthase 8.76 1 2 2 2 6.705E6 1.95 8.76 2 2 251 26.7 4.44 HVO_A0306 4-aminobutyrate aminotransferase 8.76 1 4 4 11 3.562E6 11.66 8.09 3 5 478.95 8.76 4 6 445 47.6 4.68 HVO_0214 L-lactate dehydrogenase 8.75 1 3 3 6 1.375E5 6.92 8.75 3 3 275.78 8.75 3 3 320 34.5 4.49 HVO_B0038A D-xylonate dehydratase 8.74 1 0 4 75 2.311E8 66.59 8.74 4 38 3641.53 8.74 4 37 412 45.5 4.55 HVO_1530 dolichyl-monophosphooligosaccharide--protein glycotransferase AglB 8.73 1 7 7 44 1.926E7 64.41 8.73 7 22 3226.57 8.73 7 22 1054 113.6 4.56 HVO_0151 urease accessory protein UreD 8.70 1 2 2 3 1.682E6 6.62 8.70 2 3 299 31.3 4.98 HVO_0105 FAD-dependent oxidoreductase 8.66 1 2 2 8 5.837E6 12.34 8.66 2 4 290.74 8.66 2 4 381 41.8 4.70 HVO_0699 translation initiation factor aIF-2 alpha subunit 8.65 1 2 2 23 1.306E7 30.25 8.65 2 11 1620.20 8.65 2 12 266 29.5 4.46 4557890 keratin 5 [Homo sapiens] 8.64 1 0 6 66 1.473E7 62.51 7.12 5 32 3697.16 8.64 6 34 590 62.4 8.06 56757580 "Keratin, type II cytoskeletal 5 (Cytokeratin-5) (CK-5) (Keratin-5) (K5) (58 kDa cytokeratin)" 8.64 1 0 6 66 1.473E7 62.51 7.12 5 32 3697.16 8.64 6 34 590 62.4 8.06 HVO_1079 sulfate adenylyltransferase small subunit 8.62 1 2 2 16 3.326E6 20.10 8.62 2 8 836.64 8.62 2 8 325 37.5 4.18 HVO_2860 conserved hypothetical protein 8.54 1 2 2 2 4.309E6 1.93 8.54 2 2 562 58.9 4.49 HVO_2381 UPF0272 family protein 8.52 1 3 3 36 1.387E7 59.65 8.52 3 18 2494.51 8.52 3 18 493 52.3 4.88 HVO_A0350 conserved hypothetical protein 8.45 1 2 2 7 1.077E7 3.98 8.45 2 3 264.02 8.45 2 4 213 23.8 9.64 HVO_1830 6-phosphogluconate dehydrogenase (decarboxylating) 8.36 1 2 3 18 1.661E7 21.72 8.36 3 9 1105.66 8.36 3 9 299 32.0 4.53 84040267 Keratin 6 isoform K6e [Homo sapiens] 8.33 1 0 5 55 1.463E7 42.24 3.90 3 26 3005.08 8.33 5 29 564 60.0 7.72 HVO_0899 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 8.15 1 3 3 6 1.737E7 7.02 8.15 3 3 171.25 8.15 3 3 466 49.2 4.20 HVO_0669 2-oxoacid dehydrogenase E1 component alpha subunit 8.14 1 2 2 12 1.853E7 2025.99 8.14 2 12 344 37.0 4.55 HVO_0891 ABC-type transport system ATP-binding protein (probable substrate copper) 8.13 1 1 2 13 1.787E6 19.76 8.13 2 6 910.24 8.13 2 7 283 28.6 4.35 HVO_1874 probable oxidoreductase (aldo-keto reductase family protein) 8.12 1 2 2 11 1.867E7 4.96 8.12 2 5 411.47 8.12 2 6 357 39.8 4.41 HVO_B0061 precorrin-2 C20-methyltransferase 8.09 1 2 2 4 5.247E6 4.64 8.09 2 2 152.85 8.09 2 2 235 25.3 4.63 HVO_C0042 helicase domain protein 8.08 1 6 6 65 1.884E7 112.38 8.08 6 32 4739.93 8.08 6 33 1274 144.4 4.67 HVO_1337 rpa-associated protein 8.03 1 3 3 7 9.470E6 4.69 6.26 2 3 304.16 8.03 3 4 623 64.8 3.68 HVO_2083 ABC-type transport system ATP-binding protein (probable substrate macrolides) 8.00 1 1 2 8 4.273E6 8.43 8.00 2 4 368.59 8.00 2 4 225 24.9 4.54 HVO_0733 transcription initiation factor TFB 7.98 1 0 3 22 3.161E7 19.44 7.98 3 11 844.12 7.98 3 11 326 37.2 6.00 HVO_1098 diaminopimelate decarboxylase 7.95 1 2 2 3 0.000E0 119.06 7.95 2 3 415 44.4 5.02 HVO_1699 pyridoxal phosphate-dependent aminotransferase (homolog to histidinol-phosphate aminotransferase / aspartate aminotransferase) 7.94 1 2 2 2 1.049E6 1.67 7.94 2 2 378 39.8 4.45 HVO_0590 nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase 7.89 1 2 2 12 3.458E7 15.44 7.89 2 6 569.00 7.89 2 6 355 35.6 4.30 HVO_A0158 acyl-CoA synthetase 7.85 1 1 4 35 1.015E8 39.16 7.85 4 17 1997.93 7.85 4 18 650 71.2 4.63 HVO_2374 transcription regulator (homolog to phosphate uptake regulator) 7.81 1 2 3 7 1.704E6 4.45 6.61 2 3 287.46 7.81 3 4 333 36.7 4.56 HVO_1625 conserved hypothetical protein 7.80 1 3 3 9 4.648E6 8.36 7.80 3 4 294.42 7.80 3 5 654 70.1 4.04 HVO_1327 AAA-type ATPase (CDC48 subfamily) 7.74 1 3 4 20 7.428E6 18.33 6.11 3 9 919.88 7.74 4 11 736 78.1 4.88 HVO_B0182 deoxyhypusine synthase 7.72 1 2 2 9 1.757E7 5.78 7.72 2 4 431.77 7.72 2 5 324 35.6 4.30 HVO_0041 ornithine carbamoyltransferase 7.69 1 2 2 12 7.079E6 17.67 7.69 2 6 629.26 7.69 2 6 299 32.7 4.37 HVO_2583 hydroxymethylglutaryl-CoA reductase (NADPH) 7.69 1 3 3 24 1.281E7 33.92 7.69 3 12 1111.01 7.69 3 12 403 41.1 4.73 HVO_0687 M20 family amidohydrolase 7.66 1 2 2 6 4.075E6 6.86 7.66 2 3 229.14 7.66 2 3 444 47.5 4.58 HVO_2304 molybdenum cofactor biosynthesis protein MoeA 7.64 1 2 2 18 2.887E6 25.03 7.64 2 9 899.64 7.64 2 9 406 43.1 4.60 HVO_1034 type IV pilus biogenesis complex ATPase subunit 7.62 1 3 3 21 4.894E6 30.48 4.96 2 10 1024.57 7.62 3 11 564 64.2 4.75 HVO_2516 "phosphoglycerate mutase, 2,3-biphosphateglycerate-independent type" 7.60 1 4 4 12 3.073E6 15.12 7.60 4 6 515.97 7.60 4 6 526 57.2 4.31 HVO_2209 probable branched-chain amino acid dehydrogenase E1 component alpha subunit 7.47 1 2 2 3 1.050E6 293.27 7.47 2 3 348 38.7 4.70 HVO_B0087 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 7.45 1 3 3 25 3.702E6 19.81 7.45 3 12 881.93 7.45 3 13 376 41.8 4.91 HVO_0158 TATA-binding transcription initiation factor 7.41 1 1 2 6 7.765E5 0.00 7.41 2 3 163.07 7.41 2 3 189 20.3 4.22 HVO_B0144 ABC-type transport system periplasmic substrate-binding protein (probable substrate iron-III) 7.23 1 2 2 6 1.602E6 0.00 7.23 2 3 181.45 7.23 2 3 401 44.3 4.40 HVO_0237 UPF0761 family protein 7.19 1 2 2 22 6.754E6 50.35 7.19 2 11 2757.01 7.19 2 11 445 46.7 5.14 HVO_0564 ABC-type transport system periplasmic substrate-binding protein (probable substrate maltose) 7.18 1 2 2 19 3.666E7 34.69 7.18 2 10 1405.42 7.18 2 9 432 46.8 4.18 HVO_0043 acetylornithine aminotransferase 7.14 1 2 2 13 3.140E7 17.64 7.14 2 6 909.09 7.14 2 7 378 39.7 4.67 HVO_2483 probable nucleoside deaminase (cytosine/guanine deaminase) 7.12 1 2 2 10 7.023E6 15.50 7.12 2 5 485.55 7.12 2 5 337 35.9 4.69 HVO_B0070 pyridoxal phosphate-dependent aminotransferase 7.08 1 2 2 10 1.352E7 15.64 7.08 2 5 653.97 7.08 2 5 438 46.4 4.58 HVO_B0102 glycosidase family protein 7.04 1 2 2 4 2.101E6 233.56 7.04 2 4 355 38.7 4.75 HVO_1356 sensor box histidine kinase 6.91 1 2 3 5 5.550E5 2.89 6.00 2 2 131.03 6.91 3 3 550 61.1 4.60 HVO_2127 M20 family amidohydrolase (homolog to indole-3-acetyl-aspartic acid hydrolase) 6.90 1 2 2 14 3.894E6 14.11 6.90 2 7 481.52 6.90 2 7 420 45.0 4.86 HVO_1184 DUF1511 family protein 6.86 1 2 2 12 2.956E7 14.09 6.86 2 6 770.45 6.86 2 6 379 40.3 4.22 HVO_2617 TrkA-C domain protein 6.70 1 2 2 6 3.314E6 8.24 6.70 2 3 234.03 6.70 2 3 403 42.0 4.96 HVO_1175 DUF2110 family protein 6.67 1 2 2 4 8.549E4 2.45 6.67 2 2 209.96 6.67 2 2 225 24.4 4.63 HVO_0324 arginine--tRNA ligase 6.64 1 3 3 6 2.065E6 5.97 6.64 3 3 339.10 6.64 3 3 587 65.0 4.35 HVO_0981 NADH dehydrogenase-like complex subunit H 6.59 1 2 2 6 9.229E6 8.24 6.59 2 3 338.49 6.59 2 3 349 36.9 5.19 HVO_1901 translation initiation factor aIF-2 gamma subunit 6.57 1 3 3 15 1.291E7 7.54 6.57 3 7 544.57 6.57 3 8 411 43.9 4.36 HVO_B0217 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 6.51 1 2 2 38 1.690E7 78.77 6.51 2 19 3257.39 6.51 2 19 476 50.4 4.23 HVO_1088 "folylpolyglutamate synthase / 7,8-dihydropteroate reductase / dihydropteroate synthase" 6.44 1 3 3 8 6.816E6 9.39 6.44 3 4 264.21 6.44 3 4 838 89.1 4.65 HVO_1374 acyl-CoA synthetase 6.33 1 2 3 6 2.284E6 773.88 6.33 3 6 553 61.1 4.50 HVO_2165 ABC-type transport system permease protein (homolog to LolDCE lipoprotein release factor) 6.29 1 2 2 6 4.435E4 6.75 6.29 2 3 263.42 6.29 2 3 429 44.4 5.12 HVO_0220 ATP-dependent DNA helicase MCM 6.27 1 3 3 3 3.042E6 4.42 6.27 3 3 702 78.8 4.73 HVO_2951 tryptophan--tRNA ligase 6.24 1 2 2 17 1.827E7 11.74 6.24 2 9 634.42 6.24 2 8 529 59.1 4.53 HVO_A0576 ABC-type transport system periplasmic substrate-binding protein (probable substrate branched-chain amino acids) 6.21 1 2 2 9 1.625E7 3.94 6.21 2 4 376.22 6.21 2 5 435 45.5 4.17 HVO_0907 cox-type terminal oxidase subunit I 6.18 1 2 2 10 5.519E6 2.47 6.18 2 5 337.89 6.18 2 5 599 65.7 5.11 HVO_A0466 conserved hypothetical protein 6.18 1 2 2 4 3.724E6 2.66 6.18 2 2 95.12 6.18 2 2 550 58.2 4.53 HVO_2873 flap endonuclease Fen1 6.13 1 2 2 14 1.996E5 16.88 6.13 2 7 497.77 6.13 2 7 326 36.4 4.40 HVO_2404 aminomethyltransferase (glycine cleavage system protein T) 6.06 1 1 2 6 3.290E6 0.00 6.06 2 3 144.97 6.06 2 3 363 39.7 4.25 HVO_2717 alanine--tRNA ligase 6.03 1 2 2 8 6.775E6 8.16 6.03 2 4 208.69 6.03 2 4 398 41.6 4.39 HVO_1123 thioredoxin-disulfide reductase 6.02 1 2 2 7 6.899E6 480.74 6.02 2 7 349 37.3 4.32 HVO_2536 CHP00300 family protein 6.01 1 2 2 4 1.893E6 1.79 6.01 2 2 123.15 6.01 2 2 416 44.8 4.51 HVO_B0265 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 6.01 1 2 6 14 3.082E6 6.29 3.63 5 7 295.55 4.87 5 7 1048 112.5 4.61 HVO_1806 conserved hypothetical protein 5.89 1 2 2 2 5.495E6 0.00 5.89 2 2 475 52.3 4.34 HVO_B0345 homolog to mandelate racemase / homolog to muconate lactonizing enzyme 5.82 1 2 2 8 1.891E6 11.43 5.82 2 4 332.47 5.82 2 4 378 41.2 4.84 HVO_2448 probable oxidoreductase (aldo-keto reductase family protein) 5.81 1 1 2 4 5.954E6 3.06 5.81 2 2 191.19 5.81 2 2 327 36.5 4.94 HVO_B0106 ABC-type transport system periplasmic substrate-binding protein (probable substrate sugar) 5.74 1 2 2 16 1.930E7 27.37 5.74 2 8 1221.28 5.74 2 8 488 52.6 4.13 HVO_0511 NAD-dependent epimerase/dehydratase 5.73 1 1 2 8 1.310E6 0.00 5.73 2 3 284.44 5.73 2 5 262 29.3 4.78 21961227 Keratin 6B [Homo sapiens] 5.67 1 0 4 65 3.106E7 61.26 5.67 4 32 3722.04 5.67 4 33 564 60.0 8.00 HVO_0148 urease alpha subunit 5.63 1 2 2 6 1.077E7 575.83 5.63 2 6 568 60.3 4.54 31074633 keratin 6L [Homo sapiens] 5.61 1 0 3 20 3.023E7 17.90 5.61 3 10 1228.24 5.61 3 10 535 57.8 7.20 54035279 Keratin 6L [Homo sapiens] 5.61 1 0 3 20 3.023E7 17.90 5.61 3 10 1228.24 5.61 3 10 535 57.8 7.20 39795269 Keratin 6L [Homo sapiens] 5.61 1 0 3 20 3.023E7 17.90 5.61 3 10 1228.24 5.61 3 10 535 57.7 7.20 HVO_0551 DNA mismatch repair protein MutL 5.58 1 2 3 9 6.993E5 11.78 5.58 3 4 655.75 5.58 3 5 735 78.7 4.50 1346345 "Keratin, type II cytoskeletal 6B (Cytokeratin-6B) (CK 6B) (K6b keratin)" 5.50 1 0 4 54 1.463E7 42.24 3.90 3 26 2931.44 5.50 4 28 564 60.0 8.00 1346344 "Keratin, type II cytoskeletal 6A (Cytokeratin-6A) (CK 6A) (K6a keratin)" 5.50 1 0 4 54 1.463E7 42.24 3.90 3 26 2931.44 5.50 4 28 564 60.0 8.00 1346346 "Keratin, type II cytoskeletal 6C (Cytokeratin-6C) (CK 6C) (K6c keratin)" 5.50 1 0 4 54 1.463E7 42.24 3.90 3 26 2931.44 5.50 4 28 564 60.2 8.00 HVO_1266 pyridoxal phosphate-dependent aminotransferase (probable aspartate aminotransferase) 5.48 1 1 2 6 1.405E6 2.55 5.48 2 3 139.77 5.48 2 3 383 42.0 4.49 HVO_2503 kynureninase 5.41 1 2 2 4 1.885E6 262.62 5.41 2 4 425 46.0 4.54 HVO_1113 "FtsZ family protein, type III" 5.40 1 0 2 32 5.564E7 45.19 5.40 2 16 1745.42 5.40 2 16 389 40.8 4.89 31559823 keratin 25D [Homo sapiens] 5.39 1 0 3 36 1.337E7 40.54 5.39 3 18 1900.65 5.39 3 18 464 50.6 5.47 HVO_1657 phosphoribosylamine--glycine ligase 5.37 1 2 3 16 7.545E6 16.82 5.37 3 8 940.37 4.44 2 8 428 45.5 4.20 HVO_0415 repair helicase 5.36 1 3 3 14 2.240E7 16.55 5.36 3 7 557.91 5.36 3 7 616 69.6 4.70 HVO_A0562 urocanate hydratase 5.32 1 2 2 2 2.378E6 80.89 5.32 2 2 620 67.9 4.70 HVO_0970 ribulose-bisphosphate carboxylase large subunit 5.31 1 2 2 16 6.421E6 20.82 5.31 2 9 774.56 5.31 2 7 414 43.9 4.59 HVO_B0266 glutamate dehydrogenase (NAD) 5.29 1 2 2 14 4.730E6 18.06 5.29 2 7 706.09 5.29 2 7 435 47.3 4.63 HVO_2001 tRNA-guanine(15) transglycosylase 5.23 1 2 2 5 6.143E6 17.54 5.23 2 5 516 56.3 4.59 HVO_A0088 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 4.98 1 2 5 13 1.262E6 6.29 4.00 4 6 418.94 4.98 5 7 1024 111.3 4.69 HVO_0078 hydroxymethylbilane synthase (porphobilinogen deaminase) 4.96 1 2 2 4 0.000E0 1.93 4.96 2 2 81.38 4.96 2 2 363 39.3 4.97 HVO_1260 von Willebrand factor type A domain protein 4.89 1 2 3 9 3.477E6 12.27 3.91 2 4 572.68 4.89 3 5 818 85.1 4.65 HVO_2367 arNOG05179 family protein (DUF87-related AAA-type ATPase) 4.86 1 3 3 6 3.737E6 4.80 4.86 3 3 266.11 4.86 3 3 658 72.1 4.70 HVO_A0525 enoyl-CoA hydratase 4.78 1 2 2 2 7.547E5 146.07 4.78 2 2 293 31.9 4.61 HVO_1294 GMC family oxidoreductase 4.75 1 2 2 8 1.351E7 9.84 4.75 2 4 435.07 4.75 2 4 526 56.7 4.94 HVO_1479 CHP03663 family protein 4.75 1 2 2 18 4.078E6 29.55 4.75 2 9 975.17 4.75 2 9 547 57.3 5.99 HVO_1690 DHH family phosphoesterase 4.74 1 2 2 10 3.362E6 10.98 4.74 2 5 544.79 4.74 2 5 485 52.1 4.48 HVO_0014 ATP-dependent DNA helicase Hel308a 4.72 1 3 3 6 8.479E6 2.12 4.72 3 3 147.46 3.39 2 3 827 90.3 4.67 HVO_0892 ABC-type transport system periplasmic substrate-binding protein (probable substrate copper) 4.68 1 2 2 16 1.547E7 27.66 4.68 2 8 1024.15 4.68 2 8 641 67.1 4.70 HVO_0822 glycerol-1-phosphate dehydrogenase [NAD(P)] 4.60 1 2 2 8 2.708E6 5.92 4.60 2 4 376.54 4.60 2 4 348 36.7 4.69 HVO_A0145 ABC-type transport system ATP-binding protein (probable substrate sugar) 4.59 1 0 2 4 4.943E6 3.33 4.59 2 2 261.28 4.59 2 2 392 43.4 4.56 HVO_A0035 "FtsZ family protein, type III" 4.57 1 1 2 11 1.289E6 11.63 4.57 2 5 580.42 4.57 2 6 394 41.1 4.81 HVO_0748 type IV pilus biogenesis complex ATPase subunit 4.55 1 1 2 4 3.481E5 2.28 4.55 2 2 63.01 4.55 2 2 660 68.4 4.87 HVO_2195 sensor box histidine kinase (nonfunctional) 4.42 1 2 2 2 9.009E6 92.82 4.42 2 2 679 73.3 4.98 HVO_0199 phosphohexomutase (phosphoglucomutase / phosphomannomutase) 4.38 1 2 2 8 1.997E6 3.46 4.38 2 4 196.75 4.38 2 4 457 48.4 4.35 HVO_B0143 receiver/sensor box histidine kinase 4.36 1 2 2 4 0.000E0 6.45 4.36 2 2 109.99 4.36 2 2 597 66.0 4.41 HVO_1523_A glycosyltransferase AglE 4.28 1 2 2 3 1.571E6 171.50 4.28 2 3 304 33.8 7.08 HVO_1685 conserved hypothetical protein 4.27 1 2 2 12 3.899E6 8.69 4.27 2 6 550.32 4.27 2 6 492 54.5 5.74 HVO_A0535 peptidase M24 family protein 4.25 1 2 2 2 1.503E6 86.76 4.25 2 2 424 47.2 4.81 31559829 keratin 25A [Homo sapiens] 4.00 1 0 2 20 3.201E6 22.88 4.00 2 10 1031.88 4.00 2 10 450 49.3 5.08 HVO_B0256 aldehyde ferredoxin oxidoreductase 3.96 1 0 2 2 9.506E6 78.81 3.96 2 2 555 59.9 4.55 31559819 keratin 25C [Homo sapiens] 3.92 1 0 2 20 3.201E6 22.88 3.92 2 10 1031.88 3.92 2 10 459 49.8 5.14 HVO_B0363 dimethylsulfoxide reductase subunit A (reductase subunit) 3.91 1 2 2 6 1.851E6 7.73 3.91 2 3 387.13 3.91 2 3 843 92.3 4.79 HVO_0744 homolog to carboxylate-amine ligase 3.79 1 1 2 7 1.988E6 3.33 3.79 2 3 276.87 3.79 2 4 369 41.7 4.88 HVO_2618 TrkA-C domain protein 3.79 1 2 2 2 4.102E6 2.48 3.79 2 2 501 50.6 4.49 386849 keratin type II 3.73 1 0 2 6 1.583E7 957.58 3.73 2 6 563 59.9 7.94 HVO_0283 archaea-specific helicase AshA 3.65 1 2 2 9 5.388E6 13.24 3.65 2 9 684 76.3 5.53 HVO_2736 tRNA(Met) cytidine acetyltransferase 3.58 1 2 3 5 3.481E5 0.00 3.58 3 3 92.88 2.52 2 2 754 81.2 4.96 90111766 "Keratin, type I cytoskeletal 19 (Cytokeratin-19) (CK-19) (Keratin-19) (K19)" 3.50 1 0 2 18 1.776E7 17.65 3.50 2 9 941.54 3.50 2 9 400 44.1 5.14 24234699 keratin 19 [Homo sapiens] 3.50 1 0 2 18 1.776E7 17.65 3.50 2 9 941.54 3.50 2 9 400 44.1 5.14 HVO_0681 DNA topoisomerase I 3.45 1 2 2 13 1.204E7 19.43 3.45 2 6 783.05 3.45 2 7 840 93.6 4.58 HVO_2369 conserved hypothetical protein 3.30 1 2 2 2 5.681E5 114.91 3.30 2 2 424 47.3 5.06 HVO_0940 P-type transport ATPase (probable substrate copper/metal cation) 3.26 1 2 2 2 6.807E4 2.05 3.26 2 2 828 85.9 4.53 HVO_1849 probable M28 family peptidase (homolog to aminopeptidase YwaD) 3.15 1 1 2 3 8.301E5 1.72 3.15 2 3 444 47.1 4.77 18031720 keratin protein K6irs [Homo sapiens] 3.14 1 0 2 5 2.296E6 637.93 3.14 2 5 510 55.7 6.89 HVO_1886 ABC-type transport system ATP-binding protein (probable substrate sulfate/tungstate) 3.13 1 0 2 4 7.137E5 0.00 3.13 2 2 112.29 3.13 2 2 288 30.9 5.15 28372503 keratin protein K6irs [Homo sapiens] 3.13 1 0 2 5 2.296E6 637.93 3.13 2 5 511 55.8 6.89 125081 "Keratin, type I cytoskeletal 15 (Cytokeratin-15) (CK-15) (Keratin-15) (K15)" 3.07 1 0 2 18 1.776E7 17.65 3.07 2 9 941.54 3.07 2 9 456 49.1 4.77 24430190 keratin 15 [Homo sapiens] 3.07 1 0 2 18 1.776E7 17.65 3.07 2 9 941.54 3.07 2 9 456 49.2 4.77 15618995 keratin 6 irs [Homo sapiens] 3.06 1 0 2 5 2.296E6 637.93 3.06 2 5 523 57.3 6.61 HVO_A0079 probable restriction/modification enzyme 3.03 1 2 2 4 3.066E6 219.43 3.03 2 4 1088 123.8 4.64 28173552 keratin 6 irs4 [Homo sapiens] 3.02 1 0 2 5 2.296E6 637.93 3.02 2 5 529 57.8 7.71 HVO_A0624 P-type transport ATPase (probable substrate zinc/cadmium) 3.02 1 2 2 3 1.822E6 379.18 3.02 2 3 895 92.5 4.42 28173564 keratin 6 irs3 [Homo sapiens] 2.96 1 0 2 5 2.296E6 637.93 2.96 2 5 540 58.9 7.23 HVO_B0154 receiver/sensor box histidine kinase 2.92 1 3 3 18 3.508E6 27.46 2.92 3 9 1063.14 2.92 3 9 1301 144.1 4.39 HVO_1236 acyl-CoA synthetase 2.80 1 2 2 4 1.561E6 1.71 2.80 2 2 93.61 2.80 2 2 535 59.1 4.60 48474984 "Keratin, type II cuticular Hb2 (Hair keratin, type II Hb2)" 2.53 1 0 2 3 1.355E6 129.43 2.53 2 3 513 56.6 6.74 27477127 "keratin, hair, basic, 2 [Homo sapiens]" 2.53 1 0 2 3 1.355E6 129.43 2.53 2 3 513 56.6 6.74 42760014 type II hair keratin 2 [Homo sapiens] 2.53 1 0 2 3 1.355E6 129.43 2.53 2 3 513 56.6 6.74 HVO_1580 conserved hypothetical protein 2.51 1 2 2 4 9.358E7 0.00 2.51 2 2 105.26 2.51 2 2 399 41.3 4.34 HVO_A0629 sensor box histidine kinase 2.19 1 0 3 7 2.148E6 0.00 2.19 3 4 189.60 2.19 3 3 548 59.9 4.63 4504919 keratin 8 [Homo sapiens] 2.07 1 0 2 43 1.224E7 26.22 2.07 2 21 1973.86 2.07 2 22 483 53.7 5.59 HVO_B0203 FAD-dependent oxidoreductase (GlcD/DLD_GlcF/GlpC domain fusion protein) 1.98 1 0 2 6 5.909E6 6.32 1.98 2 3 234.37 1.98 2 3 1008 109.5 4.60 HVO_2385 type IV pilus biogenesis complex ATPase subunit 1.85 1 2 2 3 8.010E5 0.00 1.85 2 3 758 83.8 4.30 HVO_3000 DNA ligase (NAD) 1.72 1 1 2 10 6.687E7 8.75 1.72 2 5 439.06 1.72 2 5 699 75.8 4.50 HVO_B0215 conserved hypothetical protein 1.67 1 1 2 5 2.255E6 2.03 1.67 2 2 136.76 1.67 2 3 1736 185.6 4.12 HVO_1793 receiver/sensor box histidine kinase (nonfunctional) 1.56 1 1 2 3 2.927E6 0.00 1.56 2 3 703 76.9 4.75 HVO_0753 conserved hypothetical protein 1.18 1 1 2 2 3.764E6 95.79 1.18 2 2 1018 106.4 4.86 HVO_1333 ATP-dependent DNA helicase 1.16 1 1 2 3 6.948E5 135.61 1.16 2 3 946 104.4 5.24 HVO_0065 DNA-directed DNA polymerase D large subunit 0.92 1 1 2 6 8.453E5 1.84 0.92 2 3 163.00 0.92 2 3 1202 133.9 4.60