Chr	Start	End	Ref	Alt	Func.refGene	Gene.refGene	GeneDetail.refGene	ExonicFunc.refGene	AAChange.refGene	phastConsElements46way	genomicSuperDups	esp6500si_all	1000g2012apr_all	cosmic65	nci60	snp137	avsift	LJB_PhyloP	LJB_PhyloP_Pred	LJB_SIFT	LJB_SIFT_Pred	LJB_PolyPhen2	LJB_PolyPhen2_Pred	LJB_LRT	LJB_LRT_Pred	LJB_MutationTaster	LJB_MutationTaster_Pred	LJB_GERP++	tumor_ref	tumor_var	misRate_tumor	normal_ref	normal_var	misRate_normal	p-value(Fisher)	strandRatio_tumor	strandRatio_normal	tumor_realign(total,ref,alt,freq)	normal_realign(total,ref,alt,freq)	p-value(Realaign)	p-value(EBcall)
chr1	15888681	15888681	A	C	exonic	DNAJC16		nonsynonymous SNV	DNAJC16:NM_015291:exon9:c.A1199C:p.K400T					ID=COSM463217;OCCURENCE=1(kidney)			0.58	0.940984	N	0.65	T	0.0	B	0.575641	N	0.980016	D	1.82	122	29	0.192	191	0	0.000	9.6625017680858469e-12	1.000	---	171,115,55,0.324	145,145,0,0.000	16.789	60
chr1	24416601	24416601	G	A	exonic	MYOM3		synonymous SNV	MYOM3:NM_152372:exon13:c.C1440T:p.P480P	Score=423;Name=lod=70																			63	8	0.113	55	0	0.000	0.00944068046104650816	0.375	---	62,51,9,0.150	51,51,0,0.000	2.453	6.54
chr1	159023333	159023333	G	A	exonic	IFI16		nonsynonymous SNV	IFI16:NM_001206567:exon10:c.G1928A:p.R643K,IFI16:NM_005531:exon10:c.G1928A:p.R643K								0.31	0.139627	N	0.52	T	0.0030	B	0.612987	NA	2.0E-6	N	-3.08	82	11	0.118	82	0	0.000	0.000874793589579679314	0.636	---	79,70,9,0.114	70,70,0,0.000	2.459	4.981
chr1	160607286	160607286	C	G	exonic	SLAMF1		nonsynonymous SNV	SLAMF1:NM_003037:exon2:c.G110C:p.R37P								0.15	0.017659	N	0.85	T	0.023	B	0.241892	N	0.013121	N	-6.01	95	21	0.181	116	0	0.000	3.5278556220206604e-07	0.381	---	102,85,17,0.167	97,96,0,0.000	5.081	11.343
chr1	161140922	161140922	C	T	exonic	PPOX		nonsynonymous SNV	PPOX:NM_000309:exon13:c.C1390T:p.R464C,PPOX:NM_001122764:exon13:c.C1390T:p.R464C	Score=552;Name=lod=233		0.000077				rs147480828	0	0.99877	C	1.0	D	1.0	D	1.0	D	0.994943	D	4.63	230	41	0.151	195	0	0.000	7.55196697092428229e-11	0.512	---	219,184,35,0.160	161,161,0,0.000	8.831	5.815
chr1	235505353	235505353	C	A	exonic	GGPS1		nonsynonymous SNV	GGPS1:NM_001037277:exon4:c.C169A:p.H57N	Score=709;Name=lod=1012							0	0.999392	C	1.0	D	0.999	D	1.0	D	0.999622	D	5.82	60	10	0.143	65	0	0.000	0.001461909040978769	0.600	---	67,58,9,0.134	60,60,0,0.000	2.489	6.849
chr2	179622365	179622365	C	A	exonic	TTN		nonsynonymous SNV	TTN:NM_133432:exon44:c.G10444T:p.D3482Y,TTN:NM_001267550:exon45:c.G10582T:p.D3528Y	Score=725;Name=lod=1179																			221	28	0.112	303	0	0.000	8.64476407198727796e-11	0.571	---	210,185,24,0.115	256,256,0,0.000	8.669	9.504
chr2	219747043	219747043	G	T	exonic	WNT10A		nonsynonymous SNV	WNT10A:NM_025216:exon2:c.G274T:p.A92S	Score=677;Name=lod=754							0.01	0.00881	N	0.86	T	0.924	D	0.999999	D	0.999933	D	4.66	243	42	0.147	207	0	0.000	3.86608889616188001e-11	0.405	---	249,210,38,0.153	183,183,0,0.000	9.637	60
chr2	220315865	220315865	G	A	exonic	SPEG		synonymous SNV	SPEG:NM_005876:exon5:c.G2121A:p.S707S					ID=COSM247555;OCCURENCE=1(prostate)															121	16	0.117	134	0	0.000	1.93902239710185758e-05	0.812	---	119,105,14,0.118	111,111,0,0.000	4.045	10.333
chr5	180041103	180041103	G	T	exonic	FLT4		nonsynonymous SNV	FLT4:NM_002020:exon24:c.C3296A:p.S1099Y,FLT4:NM_182925:exon24:c.C3296A:p.S1099Y	Score=582;Name=lod=310							0	0.998825	C	1.0	D	0.961	D	1.0	NA	0.999997	D	3.32	83	11	0.117	75	0	0.000	0.00128128127679230184	0.727	---	66,57,9,0.136	59,59,0,0.000	2.489	6.758
chr6	169648697	169648697	C	T	exonic	THBS2		nonsynonymous SNV	THBS2:NM_003247:exon4:c.G424A:p.V142I	Score=506;Name=lod=152							0.07	0.997339	C	0.83	T	0.868	D	0.998845	U	1.09E-4	N	4.45	320	45	0.123	314	0	0.000	2.02365602767764149e-13	0.578	---	307,268,38,0.124	263,263,0,0.000	10.684	13.548
chr7	5262239	5262239	G	A	exonic	WIPI2		nonsynonymous SNV	WIPI2:NM_001033520:exon5:c.G499A:p.V167M,WIPI2:NM_001033519:exon7:c.G622A:p.V208M,WIPI2:NM_016003:exon7:c.G622A:p.V208M,WIPI2:NM_001033518:exon8:c.G676A:p.V226M,WIPI2:NM_015610:exon8:c.G676A:p.V226M	Score=457;Name=lod=96							0	0.999656	C	1.0	D	0.845	P	0.999773	N	0.998085	D	5.31	80	9	0.101	80	0	0.000	0.00347671816876566737	0.556	---	71,63,8,0.113	59,59,0,0.000	2.102	5.976
chr9	35091449	35091449	A	C	exonic	PIGO		stopgain	PIGO:NM_032634:exon7:c.T2435G:p.L812X	Score=605;Name=lod=384							0.02	0.998676	C	0.904121	NA	0.731423	NA	0.977759	N	1.0	A	4.71	271	40	0.129	269	1	0.004	8.97971049498173978e-11	1.000	1.000	347,277,70,0.202	249,247,2,0.008	15.012	13.95
chr9	90501303	90501303	C	T	exonic	SPATA31E1		nonsynonymous SNV	SPATA31E1:NM_178828:exon4:c.C1901T:p.A634V								0.14	0.23333	N	0.84	T	0.0010	B	0.063036	N	0.00308	N	0.413	273	40	0.128	286	0	0.000	1.51765890025989524e-12	0.425	---	279,244,35,0.125	254,254,0,0.000	10.298	6.096
chr9	127174656	127174656	G	A	exonic	PSMB7		nonsynonymous SNV	PSMB7:NM_002799:exon4:c.C370T:p.R124W	Score=557;Name=lod=244		0.000077		ID=COSM1222330;OCCURENCE=1(large_intestine)			0.01	0.993603	C	0.99	D	0.995	D	1.0	D	0.999995	D	3.76	163	22	0.119	123	0	0.000	1.26658259689830676e-05	0.682	---	149,128,21,0.141	101,101,0,0.000	4.946	3.629
chr12	129467603	129467603	A	C	exonic	GLT1D1		nonsynonymous SNV	GLT1D1:NM_144669:exon8:c.A769C:p.I257L								0.05	0.067759	N	0.93	T	0.02	B	0.981852	N	0.197355	N	-4.98	95	11	0.104	105	0	0.000	0.000743199268351879823	0.000	---	109,89,20,0.183	89,89,0,0.000	5.429	6.769
chr17	7577538	7577538	C	T	exonic	TP53		nonsynonymous SNV	TP53:NM_001126115:exon3:c.G347A:p.R116Q,TP53:NM_001126116:exon3:c.G347A:p.R116Q,TP53:NM_001126117:exon3:c.G347A:p.R116Q,TP53:NM_001276697:exon3:c.G266A:p.R89Q,TP53:NM_001276698:exon3:c.G266A:p.R89Q,TP53:NM_001276699:exon3:c.G266A:p.R89Q,TP53:NM_001126118:exon6:c.G626A:p.R209Q,TP53:NM_000546:exon7:c.G743A:p.R248Q,TP53:NM_001126112:exon7:c.G743A:p.R248Q,TP53:NM_001126113:exon7:c.G743A:p.R248Q,TP53:NM_001126114:exon7:c.G743A:p.R248Q,TP53:NM_001276695:exon7:c.G626A:p.R209Q,TP53:NM_001276696:exon7:c.G626A:p.R209Q,TP53:NM_001276760:exon7:c.G626A:p.R209Q,TP53:NM_001276761:exon7:c.G626A:p.R209Q	Score=520;Name=lod=173		0.000077		ID=COSM99602,COSM99021,COSM99020,COSM10662;OCCURENCE=3(vulva),29(ovary),6(bone),73(breast),33(stomach),67(haematopoietic_and_lymphoid_tissue),1(soft_tissue),2(kidney),37(urinary_tract),9(pancreas),1(peritoneum),6(liver),38(oesophagus),1(pituitary),1(adrenal_gland),10(skin),5(prostate),19(lung),3(cervix),2(thyroid),32(upper_aerodigestive_tract),142(large_intestine),37(central_nervous_system),1(small_intestine),4(biliary_tract),11(endometrium)	0.041	rs11540652	0.01	0.979252	C	0.98	D	1.0	D	1.0	D	1.0	D	3.05	45	13	0.224	64	0	0.000	2.87306623182079781e-05	0.385	---	44,35,9,0.205	49,49,0,0.000	3.132	5.063
chr20	33876381	33876381	C	T	exonic	FAM83C		nonsynonymous SNV	FAM83C:NM_178468:exon3:c.G689A:p.R230H	Score=451;Name=lod=91							0	0.998129	C	0.99	D	1.0	D	0.993202	N	0.993418	D	4.45	368	46	0.111	244	0	0.000	2.74368927209466796e-10	0.391	---	347,307,39,0.113	212,212,0,0.000	8.385	11.978
chr20	57899443	57899443	A	C	exonic	EDN3		nonsynonymous SNV	EDN3:NM_207033:exon4:c.A604C:p.M202L,EDN3:NM_000114:exon5:c.A646C:p.M216L,EDN3:NM_207034:exon5:c.A646C:p.M216L								0.13	0.002323	N	1.0	D	0.0	B	0.556561	NA	1.0E-6	N	-5.8	175	23	0.116	236	0	0.000	6.94169606980409128e-09	0.000	---	197,148,49,0.249	171,171,0,0.000	14.384	11.005
chr22	36661827	36661827	T	G	exonic	APOL1		synonymous SNV	APOL1:NM_001136541:exon5:c.T891G:p.G297G,APOL1:NM_001136540:exon6:c.T945G:p.G315G,APOL1:NM_003661:exon6:c.T945G:p.G315G,APOL1:NM_145343:exon7:c.T993G:p.G331G		Score=0.909256;Name=chr22:36620662																		239	38	0.137	247	0	0.000	1.22269764990572703e-11	0.000	---	322,242,80,0.248	219,219,0,0.000	19.832	15.654
chrX	134992676	134992676	C	A	exonic	SAGE1		nonsynonymous SNV	SAGE1:NM_018666:exon16:c.C1967A:p.A656E								0.58	0.865113	N	1.0	D	0.03	B	0.979687	N	5.8E-5	N	0.185	70	19	0.213	74	0	0.000	6.06673683532052845e-06	0.526	---	70,54,16,0.229	55,55,0,0.000	4.271	6.85