"Checked" "Tags" "Pathway Protein Groups Group ID" "Pathway Accession" "Pathway Level" "Pathway Description" "Pathway Source" "# Master Proteins" "# Proteins" "# Reference Proteins" "Coverage [%]" "False" "" "1" "R-HSA-5250955" "LeafAnnotation" "Toxicity of botulinum toxin type D (botD)" "ReactomePathway" "1" "2" "5" "40" "False" "" "2" "R-HSA-5250989" "LeafAnnotation" "Toxicity of botulinum toxin type G (botG)" "ReactomePathway" "2" "3" "3" "100" "False" "" "3" "R-HSA-5250981" "LeafAnnotation" "Toxicity of botulinum toxin type F (botF)" "ReactomePathway" "1" "2" "5" "40" "False" "" "4" "WP3925" "LeafAnnotation" "Amino acid metabolism" "WikiPathway" "64" "66" "91" "73" "False" "" "5" "R-HSA-389661" "IntermediateAnnotation" "Glyoxylate metabolism and glycine degradation" "ReactomePathway" "15" "16" "29" "55" "False" "" "6" "R-HSA-204174" "LeafAnnotation" "Regulation of pyruvate dehydrogenase (PDH) complex" "ReactomePathway" "10" "11" "16" "69" "False" "" "7" "R-HSA-5362517" "IntermediateAnnotation" "Signaling by Retinoic Acid" "ReactomePathway" "10" "11" "21" "52" "False" "" "8" "R-HSA-70268" "IntermediateAnnotation" "Pyruvate metabolism" "ReactomePathway" "15" "18" "20" "90" "False" "" "9" "WP3580" "LeafAnnotation" "Methionine de novo and salvage pathway" "WikiPathway" "14" "14" "21" "67" "False" "" "10" "R-HSA-111458" "IntermediateAnnotation" "Formation of apoptosome" "ReactomePathway" "4" "4" "6" "67" "False" "" "11" "R-HSA-9627069" "LeafAnnotation" "Regulation of the apoptosome activity" "ReactomePathway" "8" "8" "11" "73" "False" "" "12" "R-HSA-1237112" "LeafAnnotation" "Methionine salvage pathway" "ReactomePathway" "5" "5" "6" "83" "False" "" "13" "WP5221" "LeafAnnotation" "2q11.2 copy number variation syndrome" "WikiPathway" "17" "19" "41" "46" "False" "" "14" "R-HSA-2564830" "LeafAnnotation" "Cytosolic iron-sulfur cluster assembly" "ReactomePathway" "7" "7" "13" "54" "False" "" "15" "R-HSA-71403" "LeafAnnotation" "Citric acid cycle (TCA cycle)" "ReactomePathway" "21" "21" "22" "95" "False" "" "16" "R-HSA-5620924" "LeafAnnotation" "Intraflagellar transport" "ReactomePathway" "20" "25" "52" "48" "False" "" "17" "R-HSA-6811434" "LeafAnnotation" "COPI-dependent Golgi-to-ER retrograde traffic" "ReactomePathway" "63" "78" "99" "79" "False" "" "18" "R-HSA-1445148" "LeafAnnotation" "Translocation of SLC2A4 (GLUT4) to the plasma membrane" "ReactomePathway" "52" "63" "70" "90" "False" "" "19" "R-HSA-2132295" "LeafAnnotation" "MHC class II antigen presentation" "ReactomePathway" "69" "83" "121" "69" "False" "" "20" "R-HSA-983189" "LeafAnnotation" "Kinesins" "ReactomePathway" "27" "39" "60" "65" "False" "" "21" "R-HSA-983231" "IntermediateAnnotation" "Factors involved in megakaryocyte development and platelet production" "ReactomePathway" "39" "49" "94" "52" "False" "" "22" "WP411" "LeafAnnotation" "mRNA processing" "WikiPathway" "103" "105" "124" "85" "False" "" "23" "WP4352" "LeafAnnotation" "Ciliary landscape" "WikiPathway" "135" "144" "210" "69" "False" "" "24" "R-HSA-167160" "LeafAnnotation" "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" "ReactomePathway" "21" "21" "27" "78" "False" "" "25" "R-HSA-72086" "LeafAnnotation" "mRNA Capping" "ReactomePathway" "23" "23" "29" "79" "False" "" "26" "R-HSA-77075" "LeafAnnotation" "RNA Pol II CTD phosphorylation and interaction with CE" "ReactomePathway" "21" "21" "27" "78" "False" "" "27" "WP410" "LeafAnnotation" "Exercise-induced circadian regulation" "WikiPathway" "23" "25" "47" "53" "False" "" "28" "WP4320" "LeafAnnotation" "Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome" "WikiPathway" "15" "17" "22" "77" "False" "" "29" "WP5119" "LeafAnnotation" "NIPBL role in DNA damage - Cornelia de Lange syndrome" "WikiPathway" "3" "3" "7" "43" "False" "" "30" "R-HSA-8953750" "LeafAnnotation" "Transcriptional Regulation by E2F6" "ReactomePathway" "10" "10" "34" "29" "False" "" "31" "R-HSA-73772" "LeafAnnotation" "RNA Polymerase I Promoter Escape" "ReactomePathway" "27" "48" "60" "80" "False" "" "32" "R-HSA-427389" "LeafAnnotation" "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" "ReactomePathway" "18" "41" "45" "91" "False" "" "33" "WP1544" "LeafAnnotation" "MicroRNAs in cardiomyocyte hypertrophy" "WikiPathway" "43" "51" "83" "61" "False" "" "34" "WP195" "LeafAnnotation" "IL-1 signaling pathway" "WikiPathway" "29" "32" "55" "58" "False" "" "35" "WP2018" "LeafAnnotation" "RANKL/RANK signaling pathway" "WikiPathway" "31" "34" "54" "63" "False" "" "36" "WP231" "LeafAnnotation" "TNF-alpha signaling pathway" "WikiPathway" "44" "47" "92" "51" "False" "" "37" "WP2637" "LeafAnnotation" "Interleukin-1 (IL-1) structural pathway" "WikiPathway" "18" "20" "42" "48" "False" "" "38" "WP366" "LeafAnnotation" "TGF-beta signaling pathway" "WikiPathway" "63" "70" "131" "53" "False" "" "39" "WP382" "LeafAnnotation" "MAPK signaling pathway" "WikiPathway" "87" "104" "243" "43" "False" "" "40" "WP3851" "LeafAnnotation" "TLR4 signaling and tolerance" "WikiPathway" "8" "8" "16" "50" "False" "" "41" "WP4329" "LeafAnnotation" "miRNA role in immune response in sepsis" "WikiPathway" "12" "13" "36" "36" "False" "" "42" "WP4496" "LeafAnnotation" "Signal transduction through IL1R" "WikiPathway" "14" "16" "33" "48" "False" "" "43" "WP4666" "LeafAnnotation" "Hepatitis B infection" "WikiPathway" "59" "69" "148" "47" "False" "" "44" "WP75" "LeafAnnotation" "Toll-like receptor signaling pathway" "WikiPathway" "28" "33" "101" "33" "False" "" "45" "R-HSA-9705671" "LeafAnnotation" "SARS-CoV-2 activates/modulates innate and adaptive immune responses" "ReactomePathway" "73" "80" "120" "67" "False" "" "46" "R-HSA-5689880" "LeafAnnotation" "Ub-specific processing proteases" "ReactomePathway" "95" "121" "204" "59" "False" "" "47" "R-HSA-2871837" "LeafAnnotation" "FCERI mediated NF-kB activation" "ReactomePathway" "59" "70" "138" "51" "False" "" "48" "R-HSA-5607764" "IntermediateAnnotation" "CLEC7A (Dectin-1) signaling" "ReactomePathway" "57" "63" "78" "81" "False" "" "49" "R-HSA-9020702" "IntermediateAnnotation" "Interleukin-1 signaling" "ReactomePathway" "59" "65" "86" "76" "False" "" "50" "R-HSA-937072" "LeafAnnotation" "TRAF6-mediated induction of TAK1 complex within TLR4 complex" "ReactomePathway" "4" "7" "15" "47" "False" "" "51" "R-HSA-975163" "LeafAnnotation" "IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation" "ReactomePathway" "4" "7" "15" "47" "False" "" "52" "R-HSA-450321" "LeafAnnotation" "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" "ReactomePathway" "9" "12" "22" "55" "False" "" "53" "R-HSA-168638" "LeafAnnotation" "NOD1/2 Signaling Pathway" "ReactomePathway" "14" "19" "36" "53" "False" "" "54" "R-HSA-445989" "LeafAnnotation" "TAK1-dependent IKK and NF-kappa-B activation" "ReactomePathway" "15" "19" "35" "54" "False" "" "55" "R-HSA-5357956" "LeafAnnotation" "TNFR1-induced NFkappaB signaling pathway" "ReactomePathway" "14" "18" "33" "55" "False" "" "56" "R-HSA-9014325" "LeafAnnotation" "TICAM1,TRAF6-dependent induction of TAK1 complex" "ReactomePathway" "3" "6" "11" "55" "False" "" "57" "R-HSA-450302" "LeafAnnotation" "activated TAK1 mediates p38 MAPK activation" "ReactomePathway" "11" "15" "23" "65" "False" "" "58" "R-HSA-937042" "LeafAnnotation" "IRAK2 mediated activation of TAK1 complex" "ReactomePathway" "3" "6" "10" "60" "False" "" "59" "R-HSA-9645460" "LeafAnnotation" "Alpha-protein kinase 1 signaling pathway" "ReactomePathway" "3" "6" "11" "55" "False" "" "60" "WP4754" "LeafAnnotation" "IL-18 signaling pathway" "WikiPathway" "116" "127" "270" "47" "False" "" "61" "R-HSA-8866652" "LeafAnnotation" "Synthesis of active ubiquitin: roles of E1 and E2 enzymes" "ReactomePathway" "14" "19" "30" "63" "False" "" "62" "WP3888" "LeafAnnotation" "VEGFA-VEGFR2 signaling" "WikiPathway" "291" "308" "427" "72" "False" "" "63" "WP4018" "LeafAnnotation" "Clear cell renal cell carcinoma pathways" "WikiPathway" "55" "62" "84" "74" "False" "" "64" "WP4629" "LeafAnnotation" "Aerobic glycolysis" "WikiPathway" "11" "12" "12" "100" "False" "" "65" "WP4949" "LeafAnnotation" "16p11.2 proximal deletion syndrome" "WikiPathway" "38" "41" "73" "56" "False" "" "66" "WP534" "LeafAnnotation" "Glycolysis and gluconeogenesis" "WikiPathway" "33" "37" "45" "82" "False" "" "67" "WP706" "LeafAnnotation" "Sudden infant death syndrome (SIDS) susceptibility pathways" "WikiPathway" "50" "52" "155" "34" "False" "" "68" "R-HSA-6798695" "LeafAnnotation" "Neutrophil degranulation" "ReactomePathway" "305" "315" "471" "67" "False" "" "69" "R-HSA-70171" "IntermediateAnnotation" "Glycolysis" "ReactomePathway" "23" "26" "27" "96" "False" "" "70" "R-HSA-114608" "LeafAnnotation" "Platelet degranulation" "ReactomePathway" "75" "75" "123" "61" "False" "" "71" "R-HSA-70263" "LeafAnnotation" "Gluconeogenesis" "ReactomePathway" "25" "27" "33" "82" "False" "" "72" "R-HSA-204005" "LeafAnnotation" "COPII-mediated vesicle transport" "ReactomePathway" "48" "49" "67" "73" "False" "" "73" "R-HSA-8876198" "LeafAnnotation" "RAB GEFs exchange GTP for GDP on RABs" "ReactomePathway" "53" "56" "87" "64" "False" "" "74" "R-HSA-6809371" "LeafAnnotation" "Formation of the cornified envelope" "ReactomePathway" "60" "76" "129" "59" "False" "" "75" "R-HSA-6805567" "IntermediateAnnotation" "Keratinization" "ReactomePathway" "65" "88" "152" "58" "False" "" "76" "WP4940" "LeafAnnotation" "15q11.2 copy number variation syndrome" "WikiPathway" "7" "7" "9" "78" "False" "" "77" "R-HSA-380320" "LeafAnnotation" "Recruitment of NuMA to mitotic centrosomes" "ReactomePathway" "47" "56" "92" "61" "False" "" "78" "R-HSA-380270" "LeafAnnotation" "Recruitment of mitotic centrosome proteins and complexes" "ReactomePathway" "39" "43" "79" "54" "False" "" "79" "WP4022" "LeafAnnotation" "Pyrimidine metabolism" "WikiPathway" "42" "43" "82" "52" "False" "" "80" "WP405" "LeafAnnotation" "Eukaryotic transcription initiation" "WikiPathway" "24" "24" "41" "59" "False" "" "81" "WP4655" "LeafAnnotation" "Cytosolic DNA-sensing pathway" "WikiPathway" "24" "25" "71" "35" "False" "" "82" "WP5222" "LeafAnnotation" "2q13 copy number variation syndrome" "WikiPathway" "22" "23" "61" "38" "False" "" "83" "WP2038" "LeafAnnotation" "Microtubule cytoskeleton regulation" "WikiPathway" "29" "30" "46" "65" "False" "" "84" "WP1403" "LeafAnnotation" "AMP-activated protein kinase signaling" "WikiPathway" "24" "30" "67" "45" "False" "" "85" "WP1559" "LeafAnnotation" "Transcription factors regulate miRNAs related to cardiac hypertrophy" "WikiPathway" "6" "6" "8" "75" "False" "" "86" "WP185" "LeafAnnotation" "Integrin-mediated cell adhesion" "WikiPathway" "55" "67" "98" "68" "False" "" "87" "WP2036" "LeafAnnotation" "TNF-related weak inducer of apoptosis (TWEAK) signaling pathway" "WikiPathway" "19" "21" "41" "51" "False" "" "88" "WP2059" "LeafAnnotation" "Alzheimer's disease and miRNA effects" "WikiPathway" "143" "167" "258" "65" "False" "" "89" "WP2261" "LeafAnnotation" "Glioblastoma signaling pathways" "WikiPathway" "40" "52" "82" "63" "False" "" "90" "WP26" "LeafAnnotation" "S1P receptor signal transduction" "WikiPathway" "14" "17" "25" "68" "False" "" "91" "WP2795" "LeafAnnotation" "Cardiac hypertrophic response" "WikiPathway" "27" "31" "54" "57" "False" "" "92" "WP306" "LeafAnnotation" "Focal adhesion" "WikiPathway" "108" "133" "194" "69" "False" "" "93" "WP3915" "LeafAnnotation" "Angiopoietin-like protein 8 regulatory pathway" "WikiPathway" "51" "63" "131" "48" "False" "" "94" "WP3929" "LeafAnnotation" "Chemokine signaling pathway" "WikiPathway" "60" "77" "164" "47" "False" "" "95" "WP3931" "LeafAnnotation" "Embryonic stem cell pluripotency pathways" "WikiPathway" "35" "46" "116" "40" "False" "" "96" "WP3932" "LeafAnnotation" "Focal adhesion: PI3K-Akt-mTOR-signaling pathway" "WikiPathway" "125" "139" "298" "47" "False" "" "97" "WP3965" "LeafAnnotation" "Lipid metabolism pathway" "WikiPathway" "19" "23" "29" "79" "False" "" "98" "WP4155" "LeafAnnotation" "Endometrial cancer" "WikiPathway" "27" "35" "62" "56" "False" "" "99" "WP4172" "LeafAnnotation" "PI3K-Akt signaling pathway" "WikiPathway" "125" "146" "332" "44" "False" "" "100" "WP4216" "LeafAnnotation" "Chromosomal and microsatellite instability in colorectal cancer" "WikiPathway" "32" "39" "72" "54" "False" "" "101" "WP4223" "LeafAnnotation" "Ras signaling" "WikiPathway" "78" "96" "180" "53" "False" "" "102" "WP4239" "LeafAnnotation" "Epithelial to mesenchymal transition in colorectal cancer" "WikiPathway" "63" "72" "158" "46" "False" "" "103" "WP4255" "LeafAnnotation" "Non-small cell lung cancer" "WikiPathway" "32" "39" "72" "54" "False" "" "104" "WP4262" "LeafAnnotation" "Breast cancer pathway" "WikiPathway" "53" "64" "152" "42" "False" "" "105" "WP4263" "LeafAnnotation" "Pancreatic adenocarcinoma pathway" "WikiPathway" "47" "56" "87" "64" "False" "" "106" "WP4396" "LeafAnnotation" "Nonalcoholic fatty liver disease" "WikiPathway" "85" "92" "155" "59" "False" "" "107" "WP4481" "LeafAnnotation" "Resistin as a regulator of inflammation" "WikiPathway" "17" "19" "33" "58" "False" "" "108" "WP4483" "LeafAnnotation" "Relationship between inflammation, COX-2 and EGFR" "WikiPathway" "12" "15" "25" "60" "False" "" "109" "WP4539" "LeafAnnotation" "Synaptic signaling pathways associated with autism spectrum disorder" "WikiPathway" "20" "26" "49" "53" "False" "" "110" "WP4564" "LeafAnnotation" "Neural crest cell migration during development" "WikiPathway" "16" "22" "39" "56" "False" "" "111" "WP4565" "LeafAnnotation" "Neural crest cell migration in cancer" "WikiPathway" "18" "24" "42" "57" "False" "" "112" "WP4566" "LeafAnnotation" "Translation inhibitors in chronically activated PDGFRA cells" "WikiPathway" "25" "31" "46" "67" "False" "" "113" "WP4658" "LeafAnnotation" "Small cell lung cancer" "WikiPathway" "40" "48" "93" "52" "False" "" "114" "WP4674" "LeafAnnotation" "Head and neck squamous cell carcinoma" "WikiPathway" "39" "44" "74" "59" "False" "" "115" "WP4685" "LeafAnnotation" "Melanoma" "WikiPathway" "30" "39" "67" "58" "False" "" "116" "WP4806" "LeafAnnotation" "EGFR tyrosine kinase inhibitor resistance" "WikiPathway" "42" "53" "84" "63" "False" "" "117" "WP481" "LeafAnnotation" "Insulin signaling" "WikiPathway" "71" "86" "160" "54" "False" "" "118" "WP4871" "LeafAnnotation" "Kisspeptin/kisspeptin receptor system in the ovary" "WikiPathway" "17" "21" "39" "54" "False" "" "119" "WP5087" "LeafAnnotation" "Malignant pleural mesothelioma" "WikiPathway" "164" "191" "428" "45" "False" "" "120" "WP5101" "LeafAnnotation" "Congenital generalized lipodystrophy" "WikiPathway" "8" "9" "18" "50" "False" "" "121" "WP5102" "LeafAnnotation" "Familial partial lipodystrophy" "WikiPathway" "11" "11" "29" "38" "False" "" "122" "WP5124" "LeafAnnotation" "Alzheimer's disease" "WikiPathway" "143" "167" "258" "65" "False" "" "123" "WP5293" "LeafAnnotation" "Acute myeloid leukemia" "WikiPathway" "22" "30" "66" "45" "False" "" "124" "WP5294" "LeafAnnotation" "Sildenafil treatment" "WikiPathway" "8" "9" "22" "41" "False" "" "125" "WP673" "LeafAnnotation" "ErbB signaling pathway" "WikiPathway" "38" "51" "90" "57" "False" "" "126" "R-HSA-1257604" "IntermediateAnnotation" "PIP3 activates AKT signaling" "ReactomePathway" "23" "31" "82" "38" "False" "" "127" "R-HSA-6804757" "LeafAnnotation" "Regulation of TP53 Degradation" "ReactomePathway" "14" "20" "36" "56" "False" "" "128" "R-HSA-389513" "LeafAnnotation" "CTLA4 inhibitory signaling" "ReactomePathway" "12" "16" "20" "80" "False" "" "129" "R-HSA-8948751" "LeafAnnotation" "Regulation of PTEN stability and activity" "ReactomePathway" "51" "56" "69" "81" "False" "" "130" "R-HSA-9755511" "IntermediateAnnotation" "KEAP1-NFE2L2 pathway" "ReactomePathway" "59" "65" "75" "87" "False" "" "131" "R-HSA-198693" "LeafAnnotation" "AKT phosphorylates targets in the nucleus" "ReactomePathway" "3" "4" "10" "40" "False" "" "132" "R-HSA-5674400" "LeafAnnotation" "Constitutive Signaling by AKT1 E17K in Cancer" "ReactomePathway" "13" "15" "26" "58" "False" "" "133" "R-HSA-9614399" "LeafAnnotation" "Regulation of localization of FOXO transcription factors" "ReactomePathway" "7" "8" "12" "67" "False" "" "134" "R-HSA-3769402" "LeafAnnotation" "Deactivation of the beta-catenin transactivating complex" "ReactomePathway" "12" "15" "42" "36" "False" "" "135" "R-HSA-389357" "LeafAnnotation" "CD28 dependent PI3K/Akt signaling" "ReactomePathway" "7" "12" "22" "55" "False" "" "136" "R-HSA-5628897" "LeafAnnotation" "TP53 Regulates Metabolic Genes" "ReactomePathway" "56" "63" "84" "75" "False" "" "137" "R-HSA-1358803" "LeafAnnotation" "Downregulation of ERBB2:ERBB3 signaling" "ReactomePathway" "5" "9" "12" "75" "False" "" "138" "R-HSA-392451" "LeafAnnotation" "G beta:gamma signalling through PI3Kgamma" "ReactomePathway" "12" "13" "25" "52" "False" "" "139" "R-HSA-9634638" "LeafAnnotation" "Estrogen-dependent nuclear events downstream of ESR-membrane signaling" "ReactomePathway" "9" "10" "24" "42" "False" "" "140" "R-HSA-198323" "LeafAnnotation" "AKT phosphorylates targets in the cytosol" "ReactomePathway" "8" "10" "14" "71" "False" "" "141" "R-HSA-6804759" "LeafAnnotation" "Regulation of TP53 Activity through Association with Co-factors" "ReactomePathway" "3" "4" "14" "29" "False" "" "142" "R-HSA-165158" "LeafAnnotation" "Activation of AKT2" "ReactomePathway" "2" "2" "4" "50" "False" "" "143" "R-HSA-5218920" "LeafAnnotation" "VEGFR2 mediated vascular permeability" "ReactomePathway" "16" "18" "26" "69" "False" "" "144" "R-HSA-9755779" "LeafAnnotation" "SARS-CoV-2 targets host intracellular signalling and regulatory pathways" "ReactomePathway" "11" "12" "12" "100" "False" "" "145" "R-HSA-9607240" "IntermediateAnnotation" "FLT3 Signaling" "ReactomePathway" "5" "8" "17" "47" "False" "" "146" "R-HSA-199418" "IntermediateAnnotation" "Negative regulation of the PI3K/AKT network" "ReactomePathway" "3" "4" "8" "50" "False" "" "147" "R-HSA-6804758" "IntermediateAnnotation" "Regulation of TP53 Activity through Acetylation" "ReactomePathway" "12" "14" "23" "61" "False" "" "148" "R-HSA-8941332" "LeafAnnotation" "RUNX2 regulates genes involved in cell migration" "ReactomePathway" "5" "6" "7" "86" "False" "" "149" "R-HSA-69202" "IntermediateAnnotation" "Cyclin E associated events during G1/S transition" "ReactomePathway" "8" "10" "28" "36" "False" "" "150" "R-HSA-69656" "IntermediateAnnotation" "Cyclin A:Cdk2-associated events at S phase entry" "ReactomePathway" "8" "10" "30" "33" "False" "" "151" "R-HSA-111447" "LeafAnnotation" "Activation of BAD and translocation to mitochondria" "ReactomePathway" "12" "14" "15" "93" "False" "" "152" "R-HSA-211163" "LeafAnnotation" "AKT-mediated inactivation of FOXO1A" "ReactomePathway" "2" "3" "4" "75" "False" "" "153" "R-HSA-165160" "LeafAnnotation" "PDE3B signalling" "ReactomePathway" "1" "1" "2" "50" "False" "" "154" "R-HSA-165181" "LeafAnnotation" "Inhibition of TSC complex formation by PKB" "ReactomePathway" "3" "3" "3" "100" "False" "" "155" "R-HSA-1989781" "LeafAnnotation" "PPARA activates gene expression" "ReactomePathway" "32" "35" "114" "31" "False" "" "156" "R-HSA-381340" "LeafAnnotation" "Transcriptional regulation of white adipocyte differentiation" "ReactomePathway" "23" "27" "83" "33" "False" "" "157" "R-HSA-212436" "IntermediateAnnotation" "Generic Transcription Pathway" "ReactomePathway" "11" "11" "353" "3" "False" "" "158" "R-HSA-6807878" "LeafAnnotation" "COPI-mediated anterograde transport" "ReactomePathway" "80" "93" "100" "93" "False" "" "159" "R-HSA-5620916" "LeafAnnotation" "VxPx cargo-targeting to cilium" "ReactomePathway" "13" "14" "21" "67" "False" "" "160" "R-HSA-199992" "IntermediateAnnotation" "trans-Golgi Network Vesicle Budding" "ReactomePathway" "5" "6" "7" "86" "False" "" "161" "R-HSA-163125" "IntermediateAnnotation" "Post-translational modification: synthesis of GPI-anchored proteins" "ReactomePathway" "13" "13" "63" "21" "False" "" "162" "R-HSA-1474228" "IntermediateAnnotation" "Degradation of the extracellular matrix" "ReactomePathway" "34" "36" "80" "45" "False" "" "163" "R-HSA-8862803" "LeafAnnotation" "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" "ReactomePathway" "12" "13" "21" "62" "False" "" "164" "R-HSA-159236" "LeafAnnotation" "Transport of Mature mRNA derived from an Intron-Containing Transcript" "ReactomePathway" "59" "62" "71" "87" "False" "" "165" "R-HSA-72187" "LeafAnnotation" "mRNA 3'-end processing" "ReactomePathway" "48" "50" "57" "88" "False" "" "166" "R-HSA-73856" "LeafAnnotation" "RNA Polymerase II Transcription Termination" "ReactomePathway" "52" "55" "66" "83" "False" "" "167" "WP179" "LeafAnnotation" "Cell cycle" "WikiPathway" "46" "51" "119" "43" "False" "" "168" "WP2037" "LeafAnnotation" "Prolactin signaling pathway" "WikiPathway" "39" "44" "76" "58" "False" "" "169" "WP2272" "LeafAnnotation" "Pathogenic Escherichia coli infection" "WikiPathway" "40" "47" "54" "87" "False" "" "170" "WP289" "LeafAnnotation" "Myometrial relaxation and contraction pathways" "WikiPathway" "66" "78" "157" "50" "False" "" "171" "WP5143" "LeafAnnotation" "GDNF signaling" "WikiPathway" "64" "71" "122" "58" "False" "" "172" "WP536" "LeafAnnotation" "Calcium regulation in cardiac cells" "WikiPathway" "62" "75" "152" "49" "False" "" "173" "R-HSA-9604323" "LeafAnnotation" "Negative regulation of NOTCH4 signaling" "ReactomePathway" "46" "49" "53" "92" "False" "" "174" "R-HSA-512988" "IntermediateAnnotation" "Interleukin-3, Interleukin-5 and GM-CSF signaling" "ReactomePathway" "5" "7" "23" "30" "False" "" "175" "R-HSA-9013700" "LeafAnnotation" "NOTCH4 Activation and Transmission of Signal to the Nucleus" "ReactomePathway" "6" "7" "11" "64" "False" "" "176" "R-HSA-75035" "LeafAnnotation" "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" "ReactomePathway" "8" "8" "13" "62" "False" "" "177" "R-HSA-5625740" "IntermediateAnnotation" "RHO GTPases activate PKNs" "ReactomePathway" "23" "25" "28" "89" "False" "" "178" "R-HSA-9735871" "IntermediateAnnotation" "SARS-CoV-1 targets host intracellular signalling and regulatory pathways" "ReactomePathway" "11" "11" "15" "73" "False" "" "179" "R-HSA-392517" "LeafAnnotation" "Rap1 signalling" "ReactomePathway" "7" "9" "15" "60" "False" "" "180" "R-HSA-450604" "LeafAnnotation" "KSRP (KHSRP) binds and destabilizes mRNA" "ReactomePathway" "14" "14" "17" "82" "False" "" "181" "R-HSA-430116" "LeafAnnotation" "GP1b-IX-V activation signalling" "ReactomePathway" "4" "6" "10" "60" "False" "" "182" "R-HSA-6803157" "IntermediateAnnotation" "Antimicrobial peptides" "ReactomePathway" "7" "8" "37" "22" "False" "" "183" "WP2911" "LeafAnnotation" "miRNA targets in ECM and membrane receptors" "WikiPathway" "18" "19" "22" "86" "False" "" "184" "R-HSA-3000178" "LeafAnnotation" "ECM proteoglycans" "ReactomePathway" "42" "43" "73" "59" "False" "" "185" "R-HSA-3000171" "IntermediateAnnotation" "Non-integrin membrane-ECM interactions" "ReactomePathway" "23" "24" "38" "63" "False" "" "186" "R-HSA-3000157" "LeafAnnotation" "Laminin interactions" "ReactomePathway" "21" "22" "28" "79" "False" "" "187" "R-HSA-8874081" "LeafAnnotation" "MET activates PTK2 signaling" "ReactomePathway" "19" "19" "27" "70" "False" "" "188" "R-HSA-379726" "LeafAnnotation" "Mitochondrial tRNA aminoacylation" "ReactomePathway" "19" "19" "21" "90" "False" "" "189" "R-HSA-6811438" "LeafAnnotation" "Intra-Golgi traffic" "ReactomePathway" "34" "37" "44" "84" "False" "" "190" "R-HSA-6811440" "LeafAnnotation" "Retrograde transport at the Trans-Golgi-Network" "ReactomePathway" "40" "42" "49" "86" "False" "" "191" "R-HSA-425986" "LeafAnnotation" "Sodium/Proton exchangers" "ReactomePathway" "3" "3" "9" "33" "False" "" "192" "R-HSA-5619092" "LeafAnnotation" "Defective SLC9A6 causes X-linked, syndromic mental retardation,, Christianson type (MRXSCH)" "ReactomePathway" "1" "1" "1" "100" "False" "" "193" "WP107" "LeafAnnotation" "Translation factors" "WikiPathway" "44" "45" "50" "90" "False" "" "194" "R-HSA-156842" "IntermediateAnnotation" "Eukaryotic Translation Elongation" "ReactomePathway" "5" "6" "6" "100" "False" "" "195" "WP2361" "LeafAnnotation" "Gastric cancer network 1" "WikiPathway" "11" "13" "28" "46" "False" "" "196" "R-HSA-8980692" "LeafAnnotation" "RHOA GTPase cycle" "ReactomePathway" "89" "94" "149" "63" "False" "" "197" "R-HSA-9013148" "LeafAnnotation" "CDC42 GTPase cycle" "ReactomePathway" "83" "90" "154" "58" "False" "" "198" "R-HSA-9013149" "LeafAnnotation" "RAC1 GTPase cycle" "ReactomePathway" "96" "105" "184" "57" "False" "" "199" "R-HSA-9013423" "LeafAnnotation" "RAC3 GTPase cycle" "ReactomePathway" "58" "61" "94" "65" "False" "" "200" "R-HSA-9013106" "LeafAnnotation" "RHOC GTPase cycle" "ReactomePathway" "55" "57" "74" "77" "False" "" "201" "R-HSA-193648" "LeafAnnotation" "NRAGE signals death through JNK" "ReactomePathway" "20" "21" "59" "36" "False" "" "202" "R-HSA-416482" "LeafAnnotation" "G alpha (12/13) signalling events" "ReactomePathway" "30" "33" "80" "41" "False" "" "203" "R-HSA-9013404" "LeafAnnotation" "RAC2 GTPase cycle" "ReactomePathway" "59" "62" "88" "70" "False" "" "204" "R-HSA-9013026" "LeafAnnotation" "RHOB GTPase cycle" "ReactomePathway" "44" "47" "70" "67" "False" "" "205" "WP4950" "LeafAnnotation" "16p11.2 distal deletion syndrome" "WikiPathway" "14" "16" "30" "53" "False" "" "206" "R-HSA-8856828" "IntermediateAnnotation" "Clathrin-mediated endocytosis" "ReactomePathway" "86" "92" "127" "72" "False" "" "207" "R-HSA-390471" "LeafAnnotation" "Association of TriC/CCT with target proteins during biosynthesis" "ReactomePathway" "23" "24" "38" "63" "False" "" "208" "WP3969" "LeafAnnotation" "H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity" "WikiPathway" "8" "8" "13" "62" "False" "" "209" "WP4536" "LeafAnnotation" "Genes related to primary cilium development (based on CRISPR)" "WikiPathway" "24" "25" "97" "26" "False" "" "210" "R-HSA-5610787" "IntermediateAnnotation" "Hedgehog 'off' state" "ReactomePathway" "23" "31" "56" "55" "False" "" "211" "R-HSA-9725370" "IntermediateAnnotation" "Signaling by ALK fusions and activated point mutants" "ReactomePathway" "35" "36" "41" "88" "False" "" "212" "WP111" "LeafAnnotation" "Electron transport chain: OXPHOS system in mitochondria" "WikiPathway" "80" "80" "103" "78" "False" "" "213" "WP623" "LeafAnnotation" "Oxidative phosphorylation" "WikiPathway" "48" "48" "60" "80" "False" "" "214" "R-HSA-611105" "IntermediateAnnotation" "Respiratory electron transport" "ReactomePathway" "72" "72" "91" "79" "False" "" "215" "R-HSA-6799198" "LeafAnnotation" "Complex I biogenesis" "ReactomePathway" "46" "46" "57" "81" "False" "" "216" "R-HSA-977225" "LeafAnnotation" "Amyloid fiber formation" "ReactomePathway" "30" "52" "80" "65" "False" "" "217" "R-HSA-1221632" "LeafAnnotation" "Meiotic synapsis" "ReactomePathway" "19" "39" "58" "67" "False" "" "218" "R-HSA-9610379" "LeafAnnotation" "HCMV Late Events" "ReactomePathway" "49" "71" "79" "90" "False" "" "219" "R-HSA-5689603" "LeafAnnotation" "UCH proteinases" "ReactomePathway" "61" "73" "96" "76" "False" "" "220" "R-HSA-8939236" "LeafAnnotation" "RUNX1 regulates transcription of genes involved in differentiation of HSCs" "ReactomePathway" "59" "85" "99" "86" "False" "" "221" "R-HSA-9609690" "LeafAnnotation" "HCMV Early Events" "ReactomePathway" "62" "93" "100" "93" "False" "" "222" "R-HSA-5578749" "LeafAnnotation" "Transcriptional regulation by small RNAs" "ReactomePathway" "43" "65" "73" "89" "False" "" "223" "R-HSA-606279" "LeafAnnotation" "Deposition of new CENPA-containing nucleosomes at the centromere" "ReactomePathway" "13" "32" "54" "59" "False" "" "224" "R-HSA-5250924" "LeafAnnotation" "B-WICH complex positively regulates rRNA expression" "ReactomePathway" "24" "45" "59" "76" "False" "" "225" "R-HSA-201722" "IntermediateAnnotation" "Formation of the beta-catenin:TCF transactivating complex" "ReactomePathway" "18" "40" "57" "70" "False" "" "226" "R-HSA-2559580" "LeafAnnotation" "Oxidative Stress Induced Senescence" "ReactomePathway" "29" "58" "93" "62" "False" "" "227" "R-HSA-3214815" "LeafAnnotation" "HDACs deacetylate histones" "ReactomePathway" "23" "48" "60" "80" "False" "" "228" "R-HSA-427413" "LeafAnnotation" "NoRC negatively regulates rRNA expression" "ReactomePathway" "36" "57" "75" "76" "False" "" "229" "R-HSA-5617472" "LeafAnnotation" "Activation of anterior HOX genes in hindbrain development during early embryogenesis" "ReactomePathway" "28" "50" "91" "55" "False" "" "230" "R-HSA-9018519" "LeafAnnotation" "Estrogen-dependent gene expression" "ReactomePathway" "44" "68" "117" "58" "False" "" "231" "R-HSA-5689901" "LeafAnnotation" "Metalloprotease DUBs" "ReactomePathway" "12" "23" "31" "74" "False" "" "232" "R-HSA-1912408" "LeafAnnotation" "Pre-NOTCH Transcription and Translation" "ReactomePathway" "18" "41" "62" "66" "False" "" "233" "R-HSA-2559582" "LeafAnnotation" "Senescence-Associated Secretory Phenotype (SASP)" "ReactomePathway" "29" "57" "80" "71" "False" "" "234" "R-HSA-3214858" "LeafAnnotation" "RMTs methylate histone arginines" "ReactomePathway" "25" "41" "48" "85" "False" "" "235" "R-HSA-8936459" "LeafAnnotation" "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" "ReactomePathway" "22" "46" "66" "70" "False" "" "236" "R-HSA-3214847" "LeafAnnotation" "HATs acetylate histones" "ReactomePathway" "27" "48" "107" "45" "False" "" "237" "R-HSA-912446" "LeafAnnotation" "Meiotic recombination" "ReactomePathway" "14" "38" "55" "69" "False" "" "238" "R-HSA-9670095" "LeafAnnotation" "Inhibition of DNA recombination at telomere" "ReactomePathway" "17" "38" "47" "81" "False" "" "239" "R-HSA-110330" "LeafAnnotation" "Recognition and association of DNA glycosylase with site containing an affected purine" "ReactomePathway" "9" "29" "36" "81" "False" "" "240" "R-HSA-110328" "LeafAnnotation" "Recognition and association of DNA glycosylase with site containing an affected pyrimidine" "ReactomePathway" "8" "28" "41" "68" "False" "" "241" "R-HSA-110329" "LeafAnnotation" "Cleavage of the damaged pyrimidine" "ReactomePathway" "8" "28" "41" "68" "False" "" "242" "R-HSA-110331" "LeafAnnotation" "Cleavage of the damaged purine" "ReactomePathway" "9" "29" "36" "81" "False" "" "243" "R-HSA-427359" "LeafAnnotation" "SIRT1 negatively regulates rRNA expression" "ReactomePathway" "9" "30" "37" "81" "False" "" "244" "R-HSA-212300" "LeafAnnotation" "PRC2 methylates histones and DNA" "ReactomePathway" "13" "34" "42" "81" "False" "" "245" "R-HSA-68616" "LeafAnnotation" "Assembly of the ORC complex at the origin of replication" "ReactomePathway" "12" "33" "38" "87" "False" "" "246" "R-HSA-5625886" "LeafAnnotation" "Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" "ReactomePathway" "9" "30" "36" "83" "False" "" "247" "R-HSA-9710421" "LeafAnnotation" "Defective pyroptosis" "ReactomePathway" "13" "34" "42" "81" "False" "" "248" "R-HSA-171306" "LeafAnnotation" "Packaging Of Telomere Ends" "ReactomePathway" "8" "28" "33" "85" "False" "" "249" "R-HSA-2299718" "LeafAnnotation" "Condensation of Prophase Chromosomes" "ReactomePathway" "12" "34" "42" "81" "False" "" "250" "R-HSA-2559586" "IntermediateAnnotation" "DNA Damage/Telomere Stress Induced Senescence" "ReactomePathway" "13" "34" "47" "72" "False" "" "251" "R-HSA-5334118" "LeafAnnotation" "DNA methylation" "ReactomePathway" "9" "30" "34" "88" "False" "" "252" "R-HSA-73728" "LeafAnnotation" "RNA Polymerase I Promoter Opening" "ReactomePathway" "10" "31" "32" "97" "False" "" "253" "R-HSA-9616222" "LeafAnnotation" "Transcriptional regulation of granulopoiesis" "ReactomePathway" "16" "38" "58" "66" "False" "" "254" "R-HSA-983168" "LeafAnnotation" "Antigen processing: Ubiquitination & Proteasome degradation" "ReactomePathway" "131" "138" "304" "45" "False" "" "255" "R-HSA-8951664" "LeafAnnotation" "Neddylation" "ReactomePathway" "112" "119" "244" "49" "False" "" "256" "R-HSA-196108" "LeafAnnotation" "Pregnenolone biosynthesis" "ReactomePathway" "7" "7" "12" "58" "False" "" "257" "R-HSA-1660514" "LeafAnnotation" "Synthesis of PIPs at the Golgi membrane" "ReactomePathway" "12" "13" "18" "72" "False" "" "258" "R-HSA-1660516" "LeafAnnotation" "Synthesis of PIPs at the early endosome membrane" "ReactomePathway" "8" "8" "16" "50" "False" "" "259" "R-HSA-1660517" "LeafAnnotation" "Synthesis of PIPs at the late endosome membrane" "ReactomePathway" "6" "6" "11" "55" "False" "" "260" "WP2865" "LeafAnnotation" "IL1 and megakaryocytes in obesity" "WikiPathway" "10" "10" "24" "42" "False" "" "261" "WP2877" "LeafAnnotation" "Vitamin D receptor pathway" "WikiPathway" "50" "54" "181" "30" "False" "" "262" "R-HSA-202733" "IntermediateAnnotation" "Cell surface interactions at the vascular wall" "ReactomePathway" "29" "35" "143" "24" "False" "" "263" "R-HSA-140875" "LeafAnnotation" "Common Pathway of Fibrin Clot Formation" "ReactomePathway" "11" "11" "21" "52" "False" "" "264" "WP2858" "LeafAnnotation" "Ectoderm differentiation" "WikiPathway" "43" "53" "137" "39" "False" "" "265" "WP399" "LeafAnnotation" "Wnt signaling pathway and pluripotency" "WikiPathway" "37" "47" "100" "47" "False" "" "266" "WP4747" "LeafAnnotation" "Netrin-UNC5B signaling pathway" "WikiPathway" "23" "26" "50" "52" "False" "" "267" "WP500" "LeafAnnotation" "Glycogen synthesis and degradation" "WikiPathway" "24" "27" "34" "79" "False" "" "268" "WP5117" "LeafAnnotation" "Cohesin complex - Cornelia de Lange syndrome" "WikiPathway" "16" "17" "29" "59" "False" "" "269" "R-HSA-6811558" "LeafAnnotation" "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" "ReactomePathway" "31" "41" "92" "45" "False" "" "270" "R-HSA-180024" "LeafAnnotation" "DARPP-32 events" "ReactomePathway" "15" "18" "23" "78" "False" "" "271" "R-HSA-195253" "IntermediateAnnotation" "Degradation of beta-catenin by the destruction complex" "ReactomePathway" "55" "60" "69" "87" "False" "" "272" "R-HSA-2467813" "LeafAnnotation" "Separation of Sister Chromatids" "ReactomePathway" "110" "124" "185" "67" "False" "" "273" "R-HSA-2500257" "LeafAnnotation" "Resolution of Sister Chromatid Cohesion" "ReactomePathway" "61" "71" "121" "59" "False" "" "274" "R-HSA-5663220" "LeafAnnotation" "RHO GTPases Activate Formins" "ReactomePathway" "70" "81" "133" "61" "False" "" "275" "R-HSA-68877" "IntermediateAnnotation" "Mitotic Prometaphase" "ReactomePathway" "53" "63" "109" "58" "False" "" "276" "R-HSA-9648025" "LeafAnnotation" "EML4 and NUDC in mitotic spindle formation" "ReactomePathway" "56" "66" "113" "58" "False" "" "277" "R-HSA-141444" "LeafAnnotation" "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" "ReactomePathway" "42" "45" "91" "49" "False" "" "278" "R-HSA-69231" "IntermediateAnnotation" "Cyclin D associated events in G1" "ReactomePathway" "19" "27" "46" "59" "False" "" "279" "R-HSA-4641262" "LeafAnnotation" "Disassembly of the destruction complex and recruitment of AXIN to the membrane" "ReactomePathway" "15" "18" "31" "58" "False" "" "280" "R-HSA-5673000" "LeafAnnotation" "RAF activation" "ReactomePathway" "23" "28" "32" "88" "False" "" "281" "R-HSA-69273" "IntermediateAnnotation" "Cyclin A/B1/B2 associated events during G2/M transition" "ReactomePathway" "11" "13" "25" "52" "False" "" "282" "R-HSA-196299" "LeafAnnotation" "Beta-catenin phosphorylation cascade" "ReactomePathway" "10" "11" "17" "65" "False" "" "283" "R-HSA-5339716" "LeafAnnotation" "Signaling by GSK3beta mutants" "ReactomePathway" "10" "11" "15" "73" "False" "" "284" "R-HSA-5358747" "LeafAnnotation" "CTNNB1 S33 mutants aren't phosphorylated" "ReactomePathway" "10" "11" "15" "73" "False" "" "285" "R-HSA-5358749" "LeafAnnotation" "CTNNB1 S37 mutants aren't phosphorylated" "ReactomePathway" "10" "11" "15" "73" "False" "" "286" "R-HSA-5358751" "LeafAnnotation" "CTNNB1 S45 mutants aren't phosphorylated" "ReactomePathway" "10" "11" "15" "73" "False" "" "287" "R-HSA-5358752" "LeafAnnotation" "CTNNB1 T41 mutants aren't phosphorylated" "ReactomePathway" "10" "11" "15" "73" "False" "" "288" "R-HSA-5467337" "LeafAnnotation" "APC truncation mutants have impaired AXIN binding" "ReactomePathway" "9" "10" "14" "71" "False" "" "289" "R-HSA-5467340" "LeafAnnotation" "AXIN missense mutants destabilize the destruction complex" "ReactomePathway" "9" "10" "14" "71" "False" "" "290" "R-HSA-5467348" "LeafAnnotation" "Truncations of AMER1 destabilize the destruction complex" "ReactomePathway" "9" "10" "14" "71" "False" "" "291" "R-HSA-2465910" "LeafAnnotation" "MASTL Facilitates Mitotic Progression" "ReactomePathway" "5" "8" "10" "80" "False" "" "292" "R-HSA-9634600" "LeafAnnotation" "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" "ReactomePathway" "7" "9" "12" "75" "False" "" "293" "R-HSA-198753" "IntermediateAnnotation" "ERK/MAPK targets" "ReactomePathway" "8" "11" "17" "65" "False" "" "294" "R-HSA-5675221" "IntermediateAnnotation" "Negative regulation of MAPK pathway" "ReactomePathway" "18" "24" "40" "60" "False" "" "295" "R-HSA-432142" "LeafAnnotation" "Platelet sensitization by LDL" "ReactomePathway" "10" "12" "17" "71" "False" "" "296" "R-HSA-113501" "LeafAnnotation" "Inhibition of replication initiation of damaged DNA by RB1/E2F1" "ReactomePathway" "5" "6" "13" "46" "False" "" "297" "R-HSA-163767" "LeafAnnotation" "PP2A-mediated dephosphorylation of key metabolic factors" "ReactomePathway" "4" "5" "7" "71" "False" "" "298" "R-HSA-202670" "LeafAnnotation" "ERKs are inactivated" "ReactomePathway" "7" "8" "13" "62" "False" "" "299" "R-HSA-163685" "IntermediateAnnotation" "Integration of energy metabolism" "ReactomePathway" "4" "5" "5" "100" "False" "" "300" "WP3527" "LeafAnnotation" "Pre-implantation embryo" "WikiPathway" "11" "12" "57" "21" "False" "" "301" "WP78" "LeafAnnotation" "TCA cycle (aka Krebs or citric acid cycle)" "WikiPathway" "16" "16" "17" "94" "False" "" "302" "R-HSA-8866654" "LeafAnnotation" "E3 ubiquitin ligases ubiquitinate target proteins" "ReactomePathway" "24" "38" "54" "70" "False" "" "303" "R-HSA-9033241" "IntermediateAnnotation" "Peroxisomal protein import" "ReactomePathway" "29" "34" "60" "57" "False" "" "304" "R-HSA-9603798" "LeafAnnotation" "Class I peroxisomal membrane protein import" "ReactomePathway" "11" "11" "19" "58" "False" "" "305" "R-HSA-446203" "IntermediateAnnotation" "Asparagine N-linked glycosylation" "ReactomePathway" "7" "7" "11" "64" "False" "" "306" "R-HSA-9694548" "LeafAnnotation" "Maturation of spike protein" "ReactomePathway" "23" "23" "37" "62" "False" "" "307" "WP183" "LeafAnnotation" "Proteasome degradation" "WikiPathway" "53" "59" "62" "95" "False" "" "308" "WP2328" "LeafAnnotation" "Allograft rejection" "WikiPathway" "23" "26" "88" "30" "False" "" "309" "WP4217" "LeafAnnotation" "Ebola virus infection in host" "WikiPathway" "74" "79" "125" "63" "False" "" "310" "R-HSA-198933" "LeafAnnotation" "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" "ReactomePathway" "25" "33" "186" "18" "False" "" "311" "R-HSA-1236974" "LeafAnnotation" "ER-Phagosome pathway" "ReactomePathway" "68" "77" "89" "87" "False" "" "312" "R-HSA-877300" "IntermediateAnnotation" "Interferon gamma signaling" "ReactomePathway" "29" "35" "87" "40" "False" "" "313" "R-HSA-909733" "IntermediateAnnotation" "Interferon alpha/beta signaling" "ReactomePathway" "24" "28" "68" "41" "False" "" "314" "R-HSA-983170" "LeafAnnotation" "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" "ReactomePathway" "24" "26" "28" "93" "False" "" "315" "R-HSA-1236977" "LeafAnnotation" "Endosomal/Vacuolar pathway" "ReactomePathway" "9" "11" "12" "92" "False" "" "316" "WP2857" "LeafAnnotation" "Mesodermal commitment pathway" "WikiPathway" "43" "48" "143" "34" "False" "" "317" "WP3183" "LeafAnnotation" "Mesodermal commitment pathway" "WikiPathway" "18" "19" "52" "37" "False" "" "318" "WP35" "LeafAnnotation" "G protein signaling pathways" "WikiPathway" "43" "56" "95" "59" "False" "" "319" "WP3869" "LeafAnnotation" "Cannabinoid receptor signaling" "WikiPathway" "6" "7" "19" "37" "False" "" "320" "WP4540" "LeafAnnotation" "Hippo signaling regulation pathways" "WikiPathway" "42" "60" "101" "59" "False" "" "321" "WP4541" "LeafAnnotation" "Hippo-Merlin signaling dysregulation" "WikiPathway" "43" "53" "93" "57" "False" "" "322" "WP4549" "LeafAnnotation" "Fragile X syndrome" "WikiPathway" "63" "69" "120" "57" "False" "" "323" "R-HSA-9700645" "LeafAnnotation" "ALK mutants bind TKIs" "ReactomePathway" "9" "9" "11" "82" "False" "" "324" "R-HSA-9664323" "LeafAnnotation" "FCGR3A-mediated IL10 synthesis" "ReactomePathway" "18" "27" "95" "28" "False" "" "325" "R-HSA-9634597" "LeafAnnotation" "GPER1 signaling" "ReactomePathway" "24" "29" "45" "64" "False" "" "326" "R-HSA-9660821" "LeafAnnotation" "ADORA2B mediated anti-inflammatory cytokines production" "ReactomePathway" "21" "26" "44" "59" "False" "" "327" "R-HSA-381676" "LeafAnnotation" "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" "ReactomePathway" "21" "24" "43" "56" "False" "" "328" "R-HSA-432040" "LeafAnnotation" "Vasopressin regulates renal water homeostasis via Aquaporins" "ReactomePathway" "17" "23" "44" "52" "False" "" "329" "R-HSA-163615" "LeafAnnotation" "PKA activation" "ReactomePathway" "8" "11" "17" "65" "False" "" "330" "R-HSA-164378" "LeafAnnotation" "PKA activation in glucagon signalling" "ReactomePathway" "9" "12" "18" "67" "False" "" "331" "R-HSA-442720" "LeafAnnotation" "CREB1 phosphorylation through the activation of Adenylate Cyclase" "ReactomePathway" "7" "8" "11" "73" "False" "" "332" "R-HSA-9013408" "LeafAnnotation" "RHOG GTPase cycle" "ReactomePathway" "51" "53" "74" "72" "False" "" "333" "R-HSA-72163" "LeafAnnotation" "mRNA Splicing - Major Pathway" "ReactomePathway" "154" "160" "202" "79" "False" "" "334" "WP5287" "LeafAnnotation" "17q12 copy number variation syndrome" "WikiPathway" "20" "20" "90" "22" "False" "" "335" "R-HSA-77289" "IntermediateAnnotation" "Mitochondrial Fatty Acid Beta-Oxidation" "ReactomePathway" "11" "12" "20" "60" "False" "" "336" "R-HSA-73614" "LeafAnnotation" "Pyrimidine salvage" "ReactomePathway" "4" "4" "11" "36" "False" "" "337" "WP3613" "LeafAnnotation" "Photodynamic therapy-induced unfolded protein response" "WikiPathway" "12" "12" "28" "43" "False" "" "338" "R-HSA-381038" "LeafAnnotation" "XBP1(S) activates chaperone genes" "ReactomePathway" "34" "34" "46" "74" "False" "" "339" "R-HSA-8873719" "LeafAnnotation" "RAB geranylgeranylation" "ReactomePathway" "40" "45" "65" "69" "False" "" "340" "R-HSA-6791226" "LeafAnnotation" "Major pathway of rRNA processing in the nucleolus and cytosol" "ReactomePathway" "159" "164" "180" "91" "False" "" "341" "R-HSA-6790901" "LeafAnnotation" "rRNA modification in the nucleus and cytosol" "ReactomePathway" "53" "54" "59" "92" "False" "" "342" "R-HSA-1482788" "LeafAnnotation" "Acyl chain remodelling of PC" "ReactomePathway" "7" "7" "27" "26" "False" "" "343" "WP4918" "LeafAnnotation" "Cellular proteostasis" "WikiPathway" "6" "6" "6" "100" "False" "" "344" "R-HSA-389957" "LeafAnnotation" "Prefoldin mediated transfer of substrate to CCT/TriC" "ReactomePathway" "24" "27" "27" "100" "False" "" "345" "R-HSA-9009391" "IntermediateAnnotation" "Extra-nuclear estrogen signaling" "ReactomePathway" "25" "28" "54" "52" "False" "" "346" "R-HSA-2219530" "LeafAnnotation" "Constitutive Signaling by Aberrant PI3K in Cancer" "ReactomePathway" "14" "21" "65" "32" "False" "" "347" "R-HSA-9673766" "LeafAnnotation" "Signaling by cytosolic PDGFRA and PDGFRB fusion proteins" "ReactomePathway" "3" "3" "3" "100" "False" "" "348" "WP4204" "LeafAnnotation" "Tumor suppressor activity of SMARCB1" "WikiPathway" "16" "21" "29" "72" "False" "" "349" "WP4321" "LeafAnnotation" "Thermogenesis" "WikiPathway" "49" "61" "108" "56" "False" "" "350" "R-HSA-9707616" "LeafAnnotation" "Heme signaling" "ReactomePathway" "11" "16" "47" "34" "False" "" "351" "R-HSA-8939243" "LeafAnnotation" "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" "ReactomePathway" "17" "21" "35" "60" "False" "" "352" "R-HSA-1368108" "LeafAnnotation" "BMAL1:CLOCK,NPAS2 activates circadian gene expression" "ReactomePathway" "5" "7" "27" "26" "False" "" "353" "R-HSA-400253" "RootAnnotation" "Circadian Clock" "ReactomePathway" "16" "23" "56" "41" "False" "" "354" "R-HSA-2151201" "LeafAnnotation" "Transcriptional activation of mitochondrial biogenesis" "ReactomePathway" "19" "23" "52" "44" "False" "" "355" "R-HSA-9707564" "IntermediateAnnotation" "Cytoprotection by HMOX1" "ReactomePathway" "34" "38" "58" "66" "False" "" "356" "R-HSA-2426168" "LeafAnnotation" "Activation of gene expression by SREBF (SREBP)" "ReactomePathway" "20" "23" "40" "57" "False" "" "357" "R-HSA-400206" "IntermediateAnnotation" "Regulation of lipid metabolism by PPARalpha" "ReactomePathway" "6" "9" "19" "47" "False" "" "358" "R-HSA-1368082" "LeafAnnotation" "RORA activates gene expression" "ReactomePathway" "4" "6" "18" "33" "False" "" "359" "R-HSA-264876" "LeafAnnotation" "Insulin processing" "ReactomePathway" "15" "17" "25" "68" "False" "" "360" "R-HSA-1362409" "IntermediateAnnotation" "Mitochondrial iron-sulfur cluster biogenesis" "ReactomePathway" "4" "4" "10" "40" "False" "" "361" "WP1772" "LeafAnnotation" "Apoptosis modulation and signaling" "WikiPathway" "15" "15" "30" "50" "False" "" "362" "WP2507" "LeafAnnotation" "Nanomaterial induced apoptosis" "WikiPathway" "13" "13" "20" "65" "False" "" "363" "WP254" "LeafAnnotation" "Apoptosis" "WikiPathway" "35" "37" "86" "43" "False" "" "364" "WP5090" "LeafAnnotation" "Complement system in neuronal development and plasticity" "WikiPathway" "44" "45" "103" "44" "False" "" "365" "R-HSA-111463" "LeafAnnotation" "SMAC (DIABLO) binds to IAPs" "ReactomePathway" "4" "4" "7" "57" "False" "" "366" "R-HSA-111464" "LeafAnnotation" "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" "ReactomePathway" "4" "4" "7" "57" "False" "" "367" "R-HSA-111457" "LeafAnnotation" "Release of apoptotic factors from the mitochondria" "ReactomePathway" "5" "5" "6" "83" "False" "" "368" "R-HSA-111469" "IntermediateAnnotation" "SMAC, XIAP-regulated apoptotic response" "ReactomePathway" "2" "2" "4" "50" "False" "" "369" "R-HSA-72203" "IntermediateAnnotation" "Processing of Capped Intron-Containing Pre-mRNA" "ReactomePathway" "58" "60" "68" "88" "False" "" "370" "R-HSA-77595" "LeafAnnotation" "Processing of Intronless Pre-mRNAs" "ReactomePathway" "17" "17" "19" "89" "False" "" "371" "WP1471" "LeafAnnotation" "Target of rapamycin signaling" "WikiPathway" "20" "24" "36" "67" "False" "" "372" "WP3850" "LeafAnnotation" "Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling" "WikiPathway" "21" "22" "36" "61" "False" "" "373" "WP4577" "LeafAnnotation" "Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway" "WikiPathway" "27" "27" "44" "61" "False" "" "374" "WP4746" "LeafAnnotation" "Thyroid hormones production and peripheral downstream signaling effects" "WikiPathway" "24" "27" "74" "36" "False" "" "375" "WP4923" "LeafAnnotation" "Autophagy" "WikiPathway" "19" "22" "30" "73" "False" "" "376" "WP4963" "LeafAnnotation" "p53 transcriptional gene network" "WikiPathway" "38" "41" "89" "46" "False" "" "377" "WP5115" "LeafAnnotation" "Network map of SARS-CoV-2 signaling pathway" "WikiPathway" "35" "38" "78" "49" "False" "" "378" "WP5180" "LeafAnnotation" "DYRK1A" "WikiPathway" "27" "28" "61" "46" "False" "" "379" "WP585" "LeafAnnotation" "Interferon type I signaling pathways" "WikiPathway" "28" "32" "54" "59" "False" "" "380" "R-HSA-9639288" "LeafAnnotation" "Amino acids regulate mTORC1" "ReactomePathway" "28" "32" "54" "59" "False" "" "381" "R-HSA-8943724" "LeafAnnotation" "Regulation of PTEN gene transcription" "ReactomePathway" "33" "38" "59" "64" "False" "" "382" "R-HSA-166208" "LeafAnnotation" "mTORC1-mediated signalling" "ReactomePathway" "18" "20" "24" "83" "False" "" "383" "R-HSA-1632852" "IntermediateAnnotation" "Macroautophagy" "ReactomePathway" "41" "47" "68" "69" "False" "" "384" "R-HSA-165159" "IntermediateAnnotation" "MTOR signalling" "ReactomePathway" "14" "16" "17" "94" "False" "" "385" "R-HSA-380972" "LeafAnnotation" "Energy dependent regulation of mTOR by LKB1-AMPK" "ReactomePathway" "18" "22" "29" "76" "False" "" "386" "R-HSA-3371571" "IntermediateAnnotation" "HSF1-dependent transactivation" "ReactomePathway" "16" "18" "18" "100" "False" "" "387" "WP51" "LeafAnnotation" "Regulation of actin cytoskeleton" "WikiPathway" "80" "95" "149" "64" "False" "" "388" "R-HSA-4420097" "IntermediateAnnotation" "VEGFA-VEGFR2 Pathway" "ReactomePathway" "38" "44" "60" "73" "False" "" "389" "R-HSA-2029482" "LeafAnnotation" "Regulation of actin dynamics for phagocytic cup formation" "ReactomePathway" "43" "52" "119" "44" "False" "" "390" "R-HSA-9664422" "LeafAnnotation" "FCGR3A-mediated phagocytosis" "ReactomePathway" "41" "52" "116" "45" "False" "" "391" "R-HSA-5663213" "LeafAnnotation" "RHO GTPases Activate WASPs and WAVEs" "ReactomePathway" "28" "30" "35" "86" "False" "" "392" "WP2032" "LeafAnnotation" "Thyroid stimulating hormone (TSH) signaling pathway" "WikiPathway" "34" "44" "68" "65" "False" "" "393" "WP23" "LeafAnnotation" "B cell receptor signaling pathway" "WikiPathway" "39" "54" "97" "56" "False" "" "394" "WP2332" "LeafAnnotation" "Interleukin-11 signaling pathway" "WikiPathway" "23" "28" "43" "65" "False" "" "395" "WP2380" "LeafAnnotation" "Brain-derived neurotrophic factor (BDNF) signaling pathway" "WikiPathway" "68" "79" "144" "55" "False" "" "396" "WP3935" "LeafAnnotation" "Leptin-insulin signaling overlap" "WikiPathway" "4" "5" "17" "29" "False" "" "397" "WP3942" "LeafAnnotation" "PPAR signaling pathway" "WikiPathway" "26" "29" "68" "43" "False" "" "398" "WP437" "LeafAnnotation" "EGF/EGFR signaling pathway" "WikiPathway" "93" "103" "161" "64" "False" "" "399" "WP5072" "LeafAnnotation" "Modulators of TCR signaling and T cell activation" "WikiPathway" "26" "30" "61" "49" "False" "" "400" "WP69" "LeafAnnotation" "T-cell receptor signaling pathway" "WikiPathway" "34" "41" "90" "46" "False" "" "401" "WP722" "LeafAnnotation" "Serotonin HTR1 group and FOS pathway" "WikiPathway" "14" "17" "32" "53" "False" "" "402" "R-HSA-2730905" "LeafAnnotation" "Role of LAT2/NTAL/LAB on calcium mobilization" "ReactomePathway" "5" "11" "71" "15" "False" "" "403" "R-HSA-202424" "LeafAnnotation" "Downstream TCR signaling" "ReactomePathway" "58" "67" "103" "65" "False" "" "404" "R-HSA-114604" "LeafAnnotation" "GPVI-mediated activation cascade" "ReactomePathway" "12" "16" "34" "47" "False" "" "405" "R-HSA-354192" "IntermediateAnnotation" "Integrin signaling" "ReactomePathway" "16" "16" "23" "70" "False" "" "406" "R-HSA-444257" "LeafAnnotation" "RSK activation" "ReactomePathway" "4" "6" "7" "86" "False" "" "407" "R-HSA-5218921" "LeafAnnotation" "VEGFR2 mediated cell proliferation" "ReactomePathway" "12" "13" "15" "87" "False" "" "408" "R-HSA-9634635" "LeafAnnotation" "Estrogen-stimulated signaling through PRKCZ" "ReactomePathway" "4" "4" "5" "80" "False" "" "409" "WP2572" "LeafAnnotation" "Primary focal segmental glomerulosclerosis (FSGS)" "WikiPathway" "49" "52" "70" "74" "False" "" "410" "WP4758" "LeafAnnotation" "Nephrotic syndrome" "WikiPathway" "24" "25" "44" "57" "False" "" "411" "R-HSA-1483196" "LeafAnnotation" "PI and PC transport between ER and Golgi membranes" "ReactomePathway" "1" "1" "1" "100" "False" "" "412" "WP5224" "LeafAnnotation" "2q37 copy number variation syndrome" "WikiPathway" "39" "46" "133" "35" "False" "" "413" "R-HSA-8964011" "LeafAnnotation" "HDL clearance" "ReactomePathway" "1" "1" "4" "25" "False" "" "414" "R-HSA-9010553" "LeafAnnotation" "Regulation of expression of SLITs and ROBOs" "ReactomePathway" "138" "148" "169" "88" "False" "" "415" "R-HSA-1169091" "LeafAnnotation" "Activation of NF-kappaB in B cells" "ReactomePathway" "52" "58" "67" "87" "False" "" "416" "R-HSA-1234176" "LeafAnnotation" "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" "ReactomePathway" "49" "54" "66" "82" "False" "" "417" "R-HSA-1236978" "LeafAnnotation" "Cross-presentation of soluble exogenous antigens (endosomes)" "ReactomePathway" "43" "44" "50" "88" "False" "" "418" "R-HSA-174113" "LeafAnnotation" "SCF-beta-TrCP mediated degradation of Emi1" "ReactomePathway" "45" "49" "55" "89" "False" "" "419" "R-HSA-174154" "LeafAnnotation" "APC/C:Cdc20 mediated degradation of Securin" "ReactomePathway" "50" "54" "67" "81" "False" "" "420" "R-HSA-174178" "LeafAnnotation" "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" "ReactomePathway" "51" "55" "72" "76" "False" "" "421" "R-HSA-174184" "LeafAnnotation" "Cdc20:Phospho-APC/C mediated degradation of Cyclin A" "ReactomePathway" "53" "57" "72" "79" "False" "" "422" "R-HSA-180534" "LeafAnnotation" "Vpu mediated degradation of CD4" "ReactomePathway" "45" "49" "52" "94" "False" "" "423" "R-HSA-180585" "LeafAnnotation" "Vif-mediated degradation of APOBEC3G" "ReactomePathway" "46" "50" "53" "94" "False" "" "424" "R-HSA-211733" "LeafAnnotation" "Regulation of activated PAK-2p34 by proteasome mediated degradation" "ReactomePathway" "44" "48" "50" "96" "False" "" "425" "R-HSA-349425" "LeafAnnotation" "Autodegradation of the E3 ubiquitin ligase COP1" "ReactomePathway" "43" "47" "52" "90" "False" "" "426" "R-HSA-350562" "LeafAnnotation" "Regulation of ornithine decarboxylase (ODC)" "ReactomePathway" "43" "44" "51" "86" "False" "" "427" "R-HSA-382556" "IntermediateAnnotation" "ABC-family proteins mediated transport" "ReactomePathway" "65" "69" "80" "86" "False" "" "428" "R-HSA-450408" "LeafAnnotation" "AUF1 (hnRNP D0) binds and destabilizes mRNA" "ReactomePathway" "47" "51" "53" "96" "False" "" "429" "R-HSA-4608870" "LeafAnnotation" "Asymmetric localization of PCP proteins" "ReactomePathway" "49" "54" "63" "86" "False" "" "430" "R-HSA-4641257" "LeafAnnotation" "Degradation of AXIN" "ReactomePathway" "44" "48" "54" "89" "False" "" "431" "R-HSA-4641258" "LeafAnnotation" "Degradation of DVL" "ReactomePathway" "45" "50" "57" "88" "False" "" "432" "R-HSA-5358346" "IntermediateAnnotation" "Hedgehog ligand biogenesis" "ReactomePathway" "50" "54" "60" "90" "False" "" "433" "R-HSA-5362768" "LeafAnnotation" "Hh mutants are degraded by ERAD" "ReactomePathway" "49" "53" "56" "95" "False" "" "434" "R-HSA-5607761" "LeafAnnotation" "Dectin-1 mediated noncanonical NF-kB signaling" "ReactomePathway" "49" "54" "60" "90" "False" "" "435" "R-HSA-5610780" "LeafAnnotation" "Degradation of GLI1 by the proteasome" "ReactomePathway" "50" "55" "60" "92" "False" "" "436" "R-HSA-5610783" "LeafAnnotation" "Degradation of GLI2 by the proteasome" "ReactomePathway" "51" "56" "60" "93" "False" "" "437" "R-HSA-5610785" "LeafAnnotation" "GLI3 is processed to GLI3R by the proteasome" "ReactomePathway" "50" "56" "60" "93" "False" "" "438" "R-HSA-5632684" "IntermediateAnnotation" "Hedgehog 'on' state" "ReactomePathway" "51" "57" "73" "78" "False" "" "439" "R-HSA-5658442" "LeafAnnotation" "Regulation of RAS by GAPs" "ReactomePathway" "52" "56" "67" "84" "False" "" "440" "R-HSA-5668541" "IntermediateAnnotation" "TNFR2 non-canonical NF-kB pathway" "ReactomePathway" "44" "48" "67" "72" "False" "" "441" "R-HSA-5676590" "LeafAnnotation" "NIK-->noncanonical NF-kB signaling" "ReactomePathway" "48" "53" "59" "90" "False" "" "442" "R-HSA-5678895" "LeafAnnotation" "Defective CFTR causes cystic fibrosis" "ReactomePathway" "53" "57" "61" "93" "False" "" "443" "R-HSA-5687128" "LeafAnnotation" "MAPK6/MAPK4 signaling" "ReactomePathway" "61" "73" "89" "82" "False" "" "444" "R-HSA-68949" "LeafAnnotation" "Orc1 removal from chromatin" "ReactomePathway" "53" "58" "71" "82" "False" "" "445" "R-HSA-69017" "LeafAnnotation" "CDK-mediated phosphorylation and removal of Cdc6" "ReactomePathway" "50" "55" "72" "76" "False" "" "446" "R-HSA-69481" "IntermediateAnnotation" "G2/M Checkpoints" "ReactomePathway" "43" "47" "51" "92" "False" "" "447" "R-HSA-69601" "LeafAnnotation" "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A" "ReactomePathway" "43" "47" "52" "90" "False" "" "448" "R-HSA-75815" "LeafAnnotation" "Ubiquitin-dependent degradation of Cyclin D" "ReactomePathway" "46" "50" "52" "96" "False" "" "449" "R-HSA-8852276" "LeafAnnotation" "The role of GTSE1 in G2/M progression after G2 checkpoint" "ReactomePathway" "60" "71" "78" "91" "False" "" "450" "R-HSA-8854050" "LeafAnnotation" "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" "ReactomePathway" "46" "50" "54" "93" "False" "" "451" "R-HSA-8939902" "LeafAnnotation" "Regulation of RUNX2 expression and activity" "ReactomePathway" "50" "55" "71" "77" "False" "" "452" "R-HSA-174084" "LeafAnnotation" "Autodegradation of Cdh1 by Cdh1:APC/C" "ReactomePathway" "49" "52" "63" "83" "False" "" "453" "R-HSA-187577" "LeafAnnotation" "SCF(Skp2)-mediated degradation of p27/p21" "ReactomePathway" "47" "51" "60" "85" "False" "" "454" "R-HSA-68867" "IntermediateAnnotation" "Assembly of the pre-replicative complex" "ReactomePathway" "57" "60" "78" "77" "False" "" "455" "R-HSA-8941858" "LeafAnnotation" "Regulation of RUNX3 expression and activity" "ReactomePathway" "45" "49" "55" "89" "False" "" "456" "R-HSA-9762114" "LeafAnnotation" "GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2" "ReactomePathway" "45" "48" "52" "92" "False" "" "457" "R-HSA-3371453" "LeafAnnotation" "Regulation of HSF1-mediated heat shock response" "ReactomePathway" "55" "57" "67" "85" "False" "" "458" "R-HSA-8856825" "LeafAnnotation" "Cargo recognition for clathrin-mediated endocytosis" "ReactomePathway" "66" "71" "103" "69" "False" "" "459" "R-HSA-429947" "LeafAnnotation" "Deadenylation of mRNA" "ReactomePathway" "21" "21" "25" "84" "False" "" "460" "R-HSA-6804115" "LeafAnnotation" "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" "ReactomePathway" "12" "12" "21" "57" "False" "" "461" "R-HSA-1679131" "LeafAnnotation" "Trafficking and processing of endosomal TLR" "ReactomePathway" "7" "7" "13" "54" "False" "" "462" "R-HSA-5602415" "LeafAnnotation" "UNC93B1 deficiency - HSE" "ReactomePathway" "1" "1" "2" "50" "False" "" "463" "WP143" "LeafAnnotation" "Fatty acid beta-oxidation" "WikiPathway" "24" "26" "34" "76" "False" "" "464" "WP357" "LeafAnnotation" "Fatty acid biosynthesis" "WikiPathway" "16" "18" "22" "82" "False" "" "465" "WP368" "LeafAnnotation" "Mitochondrial long chain fatty acid beta-oxidation" "WikiPathway" "15" "15" "17" "88" "False" "" "466" "R-HSA-77346" "LeafAnnotation" "Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA" "ReactomePathway" "6" "6" "6" "100" "False" "" "467" "R-HSA-77348" "LeafAnnotation" "Beta oxidation of octanoyl-CoA to hexanoyl-CoA" "ReactomePathway" "5" "5" "5" "100" "False" "" "468" "R-HSA-77350" "LeafAnnotation" "Beta oxidation of hexanoyl-CoA to butanoyl-CoA" "ReactomePathway" "5" "5" "5" "100" "False" "" "469" "R-HSA-77352" "LeafAnnotation" "Beta oxidation of butanoyl-CoA to acetyl-CoA" "ReactomePathway" "3" "3" "5" "60" "False" "" "470" "R-HSA-77310" "LeafAnnotation" "Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA" "ReactomePathway" "4" "4" "5" "80" "False" "" "471" "R-HSA-9668328" "LeafAnnotation" "Sealing of the nuclear envelope (NE) by ESCRT-III" "ReactomePathway" "22" "29" "31" "94" "False" "" "472" "R-HSA-5368286" "LeafAnnotation" "Mitochondrial translation initiation" "ReactomePathway" "67" "67" "88" "76" "False" "" "473" "R-HSA-5389840" "LeafAnnotation" "Mitochondrial translation elongation" "ReactomePathway" "66" "66" "87" "76" "False" "" "474" "R-HSA-5419276" "LeafAnnotation" "Mitochondrial translation termination" "ReactomePathway" "66" "66" "88" "75" "False" "" "475" "WP15" "LeafAnnotation" "Selenium micronutrient network" "WikiPathway" "44" "46" "85" "54" "False" "" "476" "WP1533" "LeafAnnotation" "Vitamin B12 metabolism" "WikiPathway" "23" "24" "50" "48" "False" "" "477" "WP176" "LeafAnnotation" "Folate metabolism" "WikiPathway" "33" "35" "68" "51" "False" "" "478" "WP1995" "LeafAnnotation" "Effects of nitric oxide" "WikiPathway" "1" "1" "8" "12" "False" "" "479" "R-HSA-2168880" "LeafAnnotation" "Scavenging of heme from plasma" "ReactomePathway" "9" "15" "70" "21" "False" "" "480" "R-HSA-1237044" "LeafAnnotation" "Erythrocytes take up carbon dioxide and release oxygen" "ReactomePathway" "2" "3" "12" "25" "False" "" "481" "R-HSA-1247673" "LeafAnnotation" "Erythrocytes take up oxygen and release carbon dioxide" "ReactomePathway" "1" "2" "8" "25" "False" "" "482" "WP4942" "LeafAnnotation" "15q13.3 copy number variation syndrome" "WikiPathway" "3" "4" "19" "21" "False" "" "483" "WP4936" "LeafAnnotation" "Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins" "WikiPathway" "12" "12" "17" "71" "False" "" "484" "WP5205" "LeafAnnotation" "Clock-controlled autophagy in bone metabolism" "WikiPathway" "27" "30" "80" "38" "False" "" "485" "R-HSA-9613829" "LeafAnnotation" "Chaperone Mediated Autophagy" "ReactomePathway" "12" "17" "22" "77" "False" "" "486" "WP477" "LeafAnnotation" "Cytoplasmic ribosomal proteins" "WikiPathway" "76" "80" "86" "93" "False" "" "487" "R-HSA-156827" "LeafAnnotation" "L13a-mediated translational silencing of Ceruloplasmin expression" "ReactomePathway" "102" "106" "110" "96" "False" "" "488" "R-HSA-72689" "LeafAnnotation" "Formation of a pool of free 40S subunits" "ReactomePathway" "92" "96" "100" "96" "False" "" "489" "R-HSA-72706" "LeafAnnotation" "GTP hydrolysis and joining of the 60S ribosomal subunit" "ReactomePathway" "103" "107" "111" "96" "False" "" "490" "R-HSA-975957" "LeafAnnotation" "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" "ReactomePathway" "99" "104" "114" "91" "False" "" "491" "R-HSA-1799339" "LeafAnnotation" "SRP-dependent cotranslational protein targeting to membrane" "ReactomePathway" "100" "105" "111" "95" "False" "" "492" "R-HSA-192823" "LeafAnnotation" "Viral mRNA Translation" "ReactomePathway" "80" "84" "88" "95" "False" "" "493" "R-HSA-9633012" "LeafAnnotation" "Response of EIF2AK4 (GCN2) to amino acid deficiency" "ReactomePathway" "85" "89" "99" "90" "False" "" "494" "R-HSA-156902" "LeafAnnotation" "Peptide chain elongation" "ReactomePathway" "80" "84" "88" "95" "False" "" "495" "R-HSA-2408557" "LeafAnnotation" "Selenocysteine synthesis" "ReactomePathway" "79" "83" "92" "90" "False" "" "496" "R-HSA-72764" "LeafAnnotation" "Eukaryotic Translation Termination" "ReactomePathway" "83" "87" "92" "95" "False" "" "497" "R-HSA-975956" "LeafAnnotation" "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" "ReactomePathway" "86" "90" "94" "96" "False" "" "498" "R-HSA-9609736" "LeafAnnotation" "Assembly and cell surface presentation of NMDA receptors" "ReactomePathway" "19" "33" "43" "77" "False" "" "499" "R-HSA-5673001" "IntermediateAnnotation" "RAF/MAP kinase cascade" "ReactomePathway" "29" "43" "116" "37" "False" "" "500" "R-HSA-442982" "LeafAnnotation" "Ras activation upon Ca2+ influx through NMDA receptor" "ReactomePathway" "6" "12" "18" "67" "False" "" "501" "R-HSA-438066" "LeafAnnotation" "Unblocking of NMDA receptors, glutamate binding and activation" "ReactomePathway" "4" "10" "20" "50" "False" "" "502" "R-HSA-9617324" "LeafAnnotation" "Negative regulation of NMDA receptor-mediated neuronal transmission" "ReactomePathway" "6" "12" "20" "60" "False" "" "503" "R-HSA-9620244" "LeafAnnotation" "Long-term potentiation" "ReactomePathway" "5" "11" "21" "52" "False" "" "504" "R-HSA-9013406" "LeafAnnotation" "RHOQ GTPase cycle" "ReactomePathway" "40" "44" "58" "76" "False" "" "505" "WP12" "LeafAnnotation" "Osteoclast signaling" "WikiPathway" "5" "5" "16" "31" "False" "" "506" "WP1434" "LeafAnnotation" "Osteopontin signaling" "WikiPathway" "9" "10" "13" "77" "False" "" "507" "WP1455" "LeafAnnotation" "Serotonin transporter activity" "WikiPathway" "5" "5" "11" "45" "False" "" "508" "WP2118" "LeafAnnotation" "Arrhythmogenic right ventricular cardiomyopathy" "WikiPathway" "39" "41" "73" "56" "False" "" "509" "WP2806" "LeafAnnotation" "Complement system" "WikiPathway" "38" "38" "92" "41" "False" "" "510" "WP322" "LeafAnnotation" "Osteoblast signaling" "WikiPathway" "5" "5" "13" "38" "False" "" "511" "WP3301" "LeafAnnotation" "MFAP5-mediated ovarian cancer cell motility and invasiveness" "WikiPathway" "10" "11" "13" "85" "False" "" "512" "WP4534" "LeafAnnotation" "Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms" "WikiPathway" "21" "24" "46" "52" "False" "" "513" "WP4560" "LeafAnnotation" "MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement" "WikiPathway" "15" "16" "18" "89" "False" "" "514" "WP727" "LeafAnnotation" "Monoamine transport" "WikiPathway" "8" "8" "32" "25" "False" "" "515" "R-HSA-216083" "LeafAnnotation" "Integrin cell surface interactions" "ReactomePathway" "48" "49" "82" "60" "False" "" "516" "R-HSA-6802952" "LeafAnnotation" "Signaling by BRAF and RAF1 fusions" "ReactomePathway" "42" "46" "63" "73" "False" "" "517" "R-HSA-445144" "LeafAnnotation" "Signal transduction by L1" "ReactomePathway" "15" "16" "20" "80" "False" "" "518" "R-HSA-3000170" "LeafAnnotation" "Syndecan interactions" "ReactomePathway" "20" "20" "25" "80" "False" "" "519" "R-HSA-6802946" "LeafAnnotation" "Signaling by moderate kinase activity BRAF mutants" "ReactomePathway" "31" "35" "44" "80" "False" "" "520" "R-HSA-6802955" "LeafAnnotation" "Paradoxical activation of RAF signaling by kinase inactive BRAF" "ReactomePathway" "31" "35" "44" "80" "False" "" "521" "R-HSA-9649948" "LeafAnnotation" "Signaling downstream of RAS mutants" "ReactomePathway" "31" "35" "44" "80" "False" "" "522" "R-HSA-9656223" "LeafAnnotation" "Signaling by RAF1 mutants" "ReactomePathway" "27" "31" "39" "79" "False" "" "523" "R-HSA-2129379" "LeafAnnotation" "Molecules associated with elastic fibres" "ReactomePathway" "20" "21" "36" "58" "False" "" "524" "R-HSA-2173789" "IntermediateAnnotation" "TGF-beta receptor signaling activates SMADs" "ReactomePathway" "18" "19" "25" "76" "False" "" "525" "R-HSA-5674135" "LeafAnnotation" "MAP2K and MAPK activation" "ReactomePathway" "28" "30" "39" "77" "False" "" "526" "R-HSA-6802948" "LeafAnnotation" "Signaling by high-kinase activity BRAF mutants" "ReactomePathway" "26" "28" "35" "80" "False" "" "527" "R-HSA-354194" "LeafAnnotation" "GRB2:SOS provides linkage to MAPK signaling for Integrins" "ReactomePathway" "11" "11" "14" "79" "False" "" "528" "R-HSA-372708" "LeafAnnotation" "p130Cas linkage to MAPK signaling for integrins" "ReactomePathway" "13" "13" "15" "87" "False" "" "529" "R-HSA-1566948" "IntermediateAnnotation" "Elastic fibre formation" "ReactomePathway" "12" "13" "18" "72" "False" "" "530" "R-HSA-210990" "LeafAnnotation" "PECAM1 interactions" "ReactomePathway" "6" "8" "11" "73" "False" "" "531" "WP3657" "LeafAnnotation" "Hematopoietic stem cell gene regulation by GABP alpha/beta complex" "WikiPathway" "5" "6" "20" "30" "False" "" "532" "WP4312" "LeafAnnotation" "Rett syndrome causing genes" "WikiPathway" "18" "24" "46" "52" "False" "" "533" "R-HSA-1266695" "LeafAnnotation" "Interleukin-7 signaling" "ReactomePathway" "7" "10" "25" "40" "False" "" "534" "R-HSA-9619665" "LeafAnnotation" "EGR2 and SOX10-mediated initiation of Schwann cell myelination" "ReactomePathway" "14" "15" "28" "54" "False" "" "535" "R-HSA-3247509" "IntermediateAnnotation" "Chromatin modifying enzymes" "ReactomePathway" "2" "3" "9" "33" "False" "" "536" "R-HSA-165054" "LeafAnnotation" "Rev-mediated nuclear export of HIV RNA" "ReactomePathway" "29" "30" "32" "94" "False" "" "537" "R-HSA-180746" "LeafAnnotation" "Nuclear import of Rev protein" "ReactomePathway" "28" "29" "31" "94" "False" "" "538" "R-HSA-9615933" "LeafAnnotation" "Postmitotic nuclear pore complex (NPC) reformation" "ReactomePathway" "23" "23" "24" "96" "False" "" "539" "R-HSA-3108214" "LeafAnnotation" "SUMOylation of DNA damage response and repair proteins" "ReactomePathway" "46" "47" "72" "65" "False" "" "540" "R-HSA-1169408" "LeafAnnotation" "ISG15 antiviral mechanism" "ReactomePathway" "53" "57" "70" "81" "False" "" "541" "R-HSA-159227" "LeafAnnotation" "Transport of the SLBP independent Mature mRNA" "ReactomePathway" "29" "30" "32" "94" "False" "" "542" "R-HSA-159230" "LeafAnnotation" "Transport of the SLBP Dependant Mature mRNA" "ReactomePathway" "29" "30" "33" "91" "False" "" "543" "R-HSA-159231" "LeafAnnotation" "Transport of Mature mRNA Derived from an Intronless Transcript" "ReactomePathway" "35" "36" "39" "92" "False" "" "544" "R-HSA-168271" "LeafAnnotation" "Transport of Ribonucleoproteins into the Host Nucleus" "ReactomePathway" "26" "27" "29" "93" "False" "" "545" "R-HSA-168276" "IntermediateAnnotation" "NS1 Mediated Effects on Host Pathways" "ReactomePathway" "30" "31" "34" "91" "False" "" "546" "R-HSA-168325" "LeafAnnotation" "Viral Messenger RNA Synthesis" "ReactomePathway" "33" "34" "41" "83" "False" "" "547" "R-HSA-168333" "LeafAnnotation" "NEP/NS2 Interacts with the Cellular Export Machinery" "ReactomePathway" "26" "27" "29" "93" "False" "" "548" "R-HSA-170822" "LeafAnnotation" "Regulation of Glucokinase by Glucokinase Regulatory Protein" "ReactomePathway" "24" "25" "29" "86" "False" "" "549" "R-HSA-180910" "LeafAnnotation" "Vpr-mediated nuclear import of PICs" "ReactomePathway" "28" "29" "31" "94" "False" "" "550" "R-HSA-191859" "LeafAnnotation" "snRNP Assembly" "ReactomePathway" "39" "41" "50" "82" "False" "" "551" "R-HSA-3232142" "LeafAnnotation" "SUMOylation of ubiquitinylation proteins" "ReactomePathway" "26" "27" "35" "77" "False" "" "552" "R-HSA-3301854" "LeafAnnotation" "Nuclear Pore Complex (NPC) Disassembly" "ReactomePathway" "27" "28" "33" "85" "False" "" "553" "R-HSA-4085377" "LeafAnnotation" "SUMOylation of SUMOylation proteins" "ReactomePathway" "26" "27" "32" "84" "False" "" "554" "R-HSA-4551638" "LeafAnnotation" "SUMOylation of chromatin organization proteins" "ReactomePathway" "35" "37" "53" "70" "False" "" "555" "R-HSA-4570464" "LeafAnnotation" "SUMOylation of RNA binding proteins" "ReactomePathway" "32" "33" "43" "77" "False" "" "556" "R-HSA-4615885" "LeafAnnotation" "SUMOylation of DNA replication proteins" "ReactomePathway" "32" "33" "42" "79" "False" "" "557" "R-HSA-5619107" "LeafAnnotation" "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" "ReactomePathway" "24" "25" "29" "86" "False" "" "558" "R-HSA-6784531" "LeafAnnotation" "tRNA processing in the nucleus" "ReactomePathway" "42" "43" "55" "78" "False" "" "559" "WP127" "LeafAnnotation" "IL-5 signaling pathway" "WikiPathway" "19" "23" "40" "57" "False" "" "560" "WP1591" "LeafAnnotation" "Heart development" "WikiPathway" "7" "7" "44" "16" "False" "" "561" "WP2034" "LeafAnnotation" "Leptin signaling pathway" "WikiPathway" "45" "52" "76" "68" "False" "" "562" "WP2203" "LeafAnnotation" "Thymic stromal lymphopoietin (TSLP) signaling pathway" "WikiPathway" "21" "25" "47" "53" "False" "" "563" "WP2253" "LeafAnnotation" "Pilocytic astrocytoma" "WikiPathway" "3" "5" "6" "83" "False" "" "564" "WP2374" "LeafAnnotation" "Oncostatin M signaling pathway" "WikiPathway" "36" "40" "65" "62" "False" "" "565" "WP244" "LeafAnnotation" "Alpha 6 beta 4 signaling pathway" "WikiPathway" "24" "25" "32" "78" "False" "" "566" "WP286" "LeafAnnotation" "IL-3 signaling pathway" "WikiPathway" "22" "26" "49" "53" "False" "" "567" "WP304" "LeafAnnotation" "Kit receptor signaling pathway" "WikiPathway" "24" "31" "59" "53" "False" "" "568" "WP313" "LeafAnnotation" "Hepatocyte growth factor receptor signaling" "WikiPathway" "22" "24" "34" "71" "False" "" "569" "WP3303" "LeafAnnotation" "RAC1/PAK1/p38/MMP2 pathway" "WikiPathway" "35" "38" "68" "56" "False" "" "570" "WP364" "LeafAnnotation" "IL6 signaling pathway" "WikiPathway" "23" "26" "43" "60" "False" "" "571" "WP3646" "LeafAnnotation" "Hepatitis C and hepatocellular carcinoma" "WikiPathway" "24" "25" "48" "52" "False" "" "572" "WP395" "LeafAnnotation" "IL-4 signaling pathway" "WikiPathway" "22" "24" "54" "44" "False" "" "573" "WP4582" "LeafAnnotation" "Cancer immunotherapy by CTLA4 blockade" "WikiPathway" "3" "5" "13" "38" "False" "" "574" "WP4585" "LeafAnnotation" "Cancer immunotherapy by PD-1 blockade" "WikiPathway" "9" "10" "23" "43" "False" "" "575" "WP4659" "LeafAnnotation" "Gastrin signaling pathway" "WikiPathway" "62" "71" "114" "62" "False" "" "576" "WP49" "LeafAnnotation" "IL-2 signaling pathway" "WikiPathway" "16" "21" "42" "50" "False" "" "577" "WP5036" "LeafAnnotation" "Angiotensin II receptor type 1 pathway" "WikiPathway" "11" "13" "24" "54" "False" "" "578" "WP5074" "LeafAnnotation" "Kallmann syndrome" "WikiPathway" "6" "6" "21" "29" "False" "" "579" "WP619" "LeafAnnotation" "Type II interferon signaling" "WikiPathway" "15" "15" "36" "42" "False" "" "580" "R-HSA-389948" "LeafAnnotation" "PD-1 signaling" "ReactomePathway" "5" "6" "29" "21" "False" "" "581" "R-HSA-936964" "LeafAnnotation" "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" "ReactomePathway" "5" "8" "16" "50" "False" "" "582" "R-HSA-391160" "LeafAnnotation" "Signal regulatory protein family interactions" "ReactomePathway" "5" "5" "13" "38" "False" "" "583" "R-HSA-8853659" "LeafAnnotation" "RET signaling" "ReactomePathway" "9" "12" "39" "31" "False" "" "584" "R-HSA-109704" "IntermediateAnnotation" "PI3K Cascade" "ReactomePathway" "6" "9" "31" "29" "False" "" "585" "R-HSA-1433557" "IntermediateAnnotation" "Signaling by SCF-KIT" "ReactomePathway" "11" "16" "33" "48" "False" "" "586" "R-HSA-186763" "LeafAnnotation" "Downstream signal transduction" "ReactomePathway" "18" "19" "26" "73" "False" "" "587" "R-HSA-210993" "LeafAnnotation" "Tie2 Signaling" "ReactomePathway" "7" "8" "16" "50" "False" "" "588" "R-HSA-388841" "IntermediateAnnotation" "Costimulation by the CD28 family" "ReactomePathway" "2" "4" "9" "44" "False" "" "589" "R-HSA-1059683" "LeafAnnotation" "Interleukin-6 signaling" "ReactomePathway" "7" "7" "11" "64" "False" "" "590" "R-HSA-2586552" "LeafAnnotation" "Signaling by Leptin" "ReactomePathway" "3" "3" "9" "33" "False" "" "591" "R-HSA-877312" "LeafAnnotation" "Regulation of IFNG signaling" "ReactomePathway" "4" "4" "12" "33" "False" "" "592" "R-HSA-912694" "LeafAnnotation" "Regulation of IFNA/IFNB signaling" "ReactomePathway" "5" "5" "22" "23" "False" "" "593" "R-HSA-9674555" "IntermediateAnnotation" "Signaling by CSF3 (G-CSF)" "ReactomePathway" "9" "10" "19" "53" "False" "" "594" "R-HSA-180292" "LeafAnnotation" "GAB1 signalosome" "ReactomePathway" "6" "7" "16" "44" "False" "" "595" "R-HSA-9680350" "IntermediateAnnotation" "Signaling by CSF1 (M-CSF) in myeloid cells" "ReactomePathway" "13" "19" "30" "63" "False" "" "596" "R-HSA-5654689" "LeafAnnotation" "PI-3K cascade:FGFR1" "ReactomePathway" "2" "3" "15" "20" "False" "" "597" "R-HSA-5654693" "LeafAnnotation" "FRS-mediated FGFR1 signaling" "ReactomePathway" "4" "4" "16" "25" "False" "" "598" "R-HSA-5654695" "LeafAnnotation" "PI-3K cascade:FGFR2" "ReactomePathway" "2" "3" "18" "17" "False" "" "599" "R-HSA-5654700" "LeafAnnotation" "FRS-mediated FGFR2 signaling" "ReactomePathway" "4" "4" "19" "21" "False" "" "600" "R-HSA-5654726" "IntermediateAnnotation" "Negative regulation of FGFR1 signaling" "ReactomePathway" "6" "9" "20" "45" "False" "" "601" "R-HSA-5654727" "IntermediateAnnotation" "Negative regulation of FGFR2 signaling" "ReactomePathway" "6" "9" "22" "41" "False" "" "602" "R-HSA-5654706" "LeafAnnotation" "FRS-mediated FGFR3 signaling" "ReactomePathway" "4" "4" "14" "29" "False" "" "603" "R-HSA-5654710" "LeafAnnotation" "PI-3K cascade:FGFR3" "ReactomePathway" "2" "3" "13" "23" "False" "" "604" "R-HSA-5654712" "LeafAnnotation" "FRS-mediated FGFR4 signaling" "ReactomePathway" "4" "5" "18" "28" "False" "" "605" "R-HSA-5654720" "LeafAnnotation" "PI-3K cascade:FGFR4" "ReactomePathway" "2" "4" "17" "24" "False" "" "606" "R-HSA-5654732" "IntermediateAnnotation" "Negative regulation of FGFR3 signaling" "ReactomePathway" "6" "9" "17" "53" "False" "" "607" "R-HSA-5654733" "IntermediateAnnotation" "Negative regulation of FGFR4 signaling" "ReactomePathway" "6" "10" "21" "48" "False" "" "608" "R-HSA-9028731" "LeafAnnotation" "Activated NTRK2 signals through FRS2 and FRS3" "ReactomePathway" "3" "3" "9" "33" "False" "" "609" "R-HSA-1295596" "LeafAnnotation" "Spry regulation of FGF signaling" "ReactomePathway" "9" "13" "14" "93" "False" "" "610" "R-HSA-110056" "LeafAnnotation" "MAPK3 (ERK1) activation" "ReactomePathway" "6" "6" "9" "67" "False" "" "611" "R-HSA-112411" "LeafAnnotation" "MAPK1 (ERK2) activation" "ReactomePathway" "5" "5" "8" "62" "False" "" "612" "R-HSA-1170546" "LeafAnnotation" "Prolactin receptor signaling" "ReactomePathway" "3" "3" "14" "21" "False" "" "613" "R-HSA-8854691" "LeafAnnotation" "Interleukin-20 family signaling" "ReactomePathway" "6" "6" "25" "24" "False" "" "614" "R-HSA-418886" "LeafAnnotation" "Netrin mediated repulsion signals" "ReactomePathway" "2" "2" "8" "25" "False" "" "615" "R-HSA-9008059" "LeafAnnotation" "Interleukin-37 signaling" "ReactomePathway" "11" "11" "21" "52" "False" "" "616" "R-HSA-9703648" "IntermediateAnnotation" "Signaling by FLT3 ITD and TKD mutants" "ReactomePathway" "4" "6" "9" "67" "False" "" "617" "R-HSA-8865999" "LeafAnnotation" "MET activates PTPN11" "ReactomePathway" "2" "2" "4" "50" "False" "" "618" "R-HSA-9702518" "LeafAnnotation" "STAT5 activation downstream of FLT3 ITD mutants" "ReactomePathway" "4" "5" "10" "50" "False" "" "619" "R-HSA-8934593" "LeafAnnotation" "Regulation of RUNX1 Expression and Activity" "ReactomePathway" "9" "13" "17" "76" "False" "" "620" "R-HSA-9645135" "LeafAnnotation" "STAT5 Activation" "ReactomePathway" "1" "2" "6" "33" "False" "" "621" "WP4917" "LeafAnnotation" "Proximal tubule transport" "WikiPathway" "21" "22" "57" "39" "False" "" "622" "R-HSA-1222556" "IntermediateAnnotation" "ROS and RNS production in phagocytes" "ReactomePathway" "15" "17" "34" "50" "False" "" "623" "R-HSA-77387" "LeafAnnotation" "Insulin receptor recycling" "ReactomePathway" "18" "20" "30" "67" "False" "" "624" "R-HSA-917977" "LeafAnnotation" "Transferrin endocytosis and recycling" "ReactomePathway" "17" "20" "30" "67" "False" "" "625" "R-HSA-983712" "IntermediateAnnotation" "Ion channel transport" "ReactomePathway" "14" "16" "24" "67" "False" "" "626" "R-HSA-171319" "LeafAnnotation" "Telomere Extension By Telomerase" "ReactomePathway" "13" "14" "23" "61" "False" "" "627" "WP4553" "LeafAnnotation" "FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma" "WikiPathway" "6" "11" "21" "52" "False" "" "628" "R-HSA-9662360" "LeafAnnotation" "Sensory processing of sound by inner hair cells of the cochlea" "ReactomePathway" "29" "31" "65" "48" "False" "" "629" "R-HSA-9662361" "IntermediateAnnotation" "Sensory processing of sound by outer hair cells of the cochlea" "ReactomePathway" "24" "25" "47" "53" "False" "" "630" "WP2882" "LeafAnnotation" "Nuclear receptors meta-pathway" "WikiPathway" "106" "115" "308" "37" "False" "" "631" "WP2884" "LeafAnnotation" "NRF2 pathway" "WikiPathway" "52" "57" "138" "41" "False" "" "632" "WP4719" "LeafAnnotation" "Eicosanoid metabolism via cyclooxygenases (COX)" "WikiPathway" "12" "13" "30" "43" "False" "" "633" "WP4721" "LeafAnnotation" "Eicosanoid metabolism via lipooxygenases (LOX)" "WikiPathway" "9" "9" "29" "31" "False" "" "634" "WP5171" "LeafAnnotation" "Leukotriene metabolic pathway" "WikiPathway" "3" "3" "11" "27" "False" "" "635" "R-HSA-2142691" "LeafAnnotation" "Synthesis of Leukotrienes (LT) and Eoxins (EX)" "ReactomePathway" "4" "4" "21" "19" "False" "" "636" "R-HSA-2142700" "LeafAnnotation" "Synthesis of Lipoxins (LX)" "ReactomePathway" "1" "1" "6" "17" "False" "" "637" "WP1272" "LeafAnnotation" "Selenium micronutrient network" "WikiPathway" "4" "4" "7" "57" "False" "" "638" "WP1273" "LeafAnnotation" "Folic acid network" "WikiPathway" "2" "2" "2" "100" "False" "" "639" "WP1310" "LeafAnnotation" "Selenium micronutrient network" "WikiPathway" "4" "4" "7" "57" "False" "" "640" "WP1311" "LeafAnnotation" "Folic acid network" "WikiPathway" "2" "2" "2" "100" "False" "" "641" "R-HSA-450520" "LeafAnnotation" "HuR (ELAVL1) binds and stabilizes mRNA" "ReactomePathway" "7" "7" "8" "88" "False" "" "642" "WP3995" "LeafAnnotation" "Prion disease pathway" "WikiPathway" "18" "19" "33" "58" "False" "" "643" "WP4673" "LeafAnnotation" "Male infertility" "WikiPathway" "35" "42" "142" "30" "False" "" "644" "R-HSA-420029" "LeafAnnotation" "Tight junction interactions" "ReactomePathway" "5" "5" "29" "17" "False" "" "645" "WP1530" "LeafAnnotation" "miRNA regulation of DNA damage response" "WikiPathway" "27" "31" "72" "43" "False" "" "646" "WP466" "LeafAnnotation" "DNA replication" "WikiPathway" "17" "20" "42" "48" "False" "" "647" "WP4753" "LeafAnnotation" "Nucleotide excision repair" "WikiPathway" "24" "24" "44" "55" "False" "" "648" "WP4946" "LeafAnnotation" "DNA repair pathways, full network" "WikiPathway" "44" "45" "118" "38" "False" "" "649" "WP5114" "LeafAnnotation" "Nucleotide excision repair in xeroderma pigmentosum" "WikiPathway" "27" "27" "54" "50" "False" "" "650" "WP531" "LeafAnnotation" "DNA mismatch repair" "WikiPathway" "11" "11" "23" "48" "False" "" "651" "WP707" "LeafAnnotation" "DNA damage response" "WikiPathway" "27" "31" "70" "44" "False" "" "652" "R-HSA-5651801" "LeafAnnotation" "PCNA-Dependent Long Patch Base Excision Repair" "ReactomePathway" "11" "11" "21" "52" "False" "" "653" "R-HSA-5656169" "LeafAnnotation" "Termination of translesion DNA synthesis" "ReactomePathway" "15" "18" "32" "56" "False" "" "654" "R-HSA-5685942" "IntermediateAnnotation" "HDR through Homologous Recombination (HRR)" "ReactomePathway" "13" "16" "48" "33" "False" "" "655" "R-HSA-6782135" "LeafAnnotation" "Dual incision in TC-NER" "ReactomePathway" "38" "41" "65" "63" "False" "" "656" "R-HSA-6782210" "LeafAnnotation" "Gap-filling DNA repair synthesis and ligation in TC-NER" "ReactomePathway" "38" "41" "63" "65" "False" "" "657" "R-HSA-110312" "LeafAnnotation" "Translesion synthesis by REV1" "ReactomePathway" "8" "11" "16" "69" "False" "" "658" "R-HSA-5655862" "LeafAnnotation" "Translesion synthesis by POLK" "ReactomePathway" "8" "11" "17" "65" "False" "" "659" "R-HSA-5656121" "LeafAnnotation" "Translesion synthesis by POLI" "ReactomePathway" "9" "12" "17" "71" "False" "" "660" "R-HSA-110314" "LeafAnnotation" "Recognition of DNA damage by PCNA-containing replication complex" "ReactomePathway" "14" "17" "30" "57" "False" "" "661" "R-HSA-5696400" "LeafAnnotation" "Dual Incision in GG-NER" "ReactomePathway" "20" "23" "41" "56" "False" "" "662" "R-HSA-174411" "LeafAnnotation" "Polymerase switching on the C-strand of the telomere" "ReactomePathway" "7" "7" "26" "27" "False" "" "663" "R-HSA-69091" "LeafAnnotation" "Polymerase switching" "ReactomePathway" "5" "5" "14" "36" "False" "" "664" "R-HSA-110320" "LeafAnnotation" "Translesion Synthesis by POLH" "ReactomePathway" "11" "14" "19" "74" "False" "" "665" "R-HSA-5696397" "LeafAnnotation" "Gap-filling DNA repair synthesis and ligation in GG-NER" "ReactomePathway" "10" "13" "24" "54" "False" "" "666" "R-HSA-1660499" "LeafAnnotation" "Synthesis of PIPs at the plasma membrane" "ReactomePathway" "24" "29" "53" "55" "False" "" "667" "WP3287" "LeafAnnotation" "Overview of nanoparticle effects" "WikiPathway" "6" "9" "18" "50" "False" "" "668" "WP4707" "LeafAnnotation" "Aspirin and miRNAs" "WikiPathway" "5" "6" "10" "60" "False" "" "669" "WP5122" "LeafAnnotation" "Prostaglandin and leukotriene metabolism in senescence" "WikiPathway" "10" "12" "26" "46" "False" "" "670" "WP5155" "LeafAnnotation" "Arachidonic acid (AA, ARA) oxylipin metabolism" "WikiPathway" "2" "3" "4" "75" "False" "" "671" "WP98" "LeafAnnotation" "Prostaglandin synthesis and regulation" "WikiPathway" "15" "18" "44" "41" "False" "" "672" "R-HSA-2162123" "LeafAnnotation" "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" "ReactomePathway" "8" "10" "15" "67" "False" "" "673" "R-HSA-140180" "LeafAnnotation" "COX reactions" "ReactomePathway" "1" "1" "1" "100" "False" "" "674" "R-HSA-381426" "LeafAnnotation" "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" "ReactomePathway" "61" "61" "123" "50" "False" "" "675" "R-HSA-8957275" "LeafAnnotation" "Post-translational protein phosphorylation" "ReactomePathway" "57" "57" "106" "54" "False" "" "676" "WP4657" "LeafAnnotation" "22q11.2 copy number variation syndrome" "WikiPathway" "46" "51" "117" "44" "False" "" "677" "R-HSA-1855183" "LeafAnnotation" "Synthesis of IP2, IP, and Ins in the cytosol" "ReactomePathway" "7" "7" "14" "50" "False" "" "678" "R-HSA-6794361" "LeafAnnotation" "Neurexins and neuroligins" "ReactomePathway" "18" "21" "59" "36" "False" "" "679" "WP4932" "LeafAnnotation" "7q11.23 copy number variation syndrome" "WikiPathway" "56" "59" "95" "62" "False" "" "680" "R-HSA-8949613" "LeafAnnotation" "Cristae formation" "ReactomePathway" "25" "25" "31" "81" "False" "" "681" "R-HSA-163210" "LeafAnnotation" "Formation of ATP by chemiosmotic coupling" "ReactomePathway" "14" "14" "18" "78" "False" "" "682" "R-HSA-163560" "LeafAnnotation" "Triglyceride catabolism" "ReactomePathway" "11" "12" "24" "50" "False" "" "683" "R-HSA-1483166" "LeafAnnotation" "Synthesis of PA" "ReactomePathway" "15" "15" "39" "38" "False" "" "684" "R-HSA-426486" "LeafAnnotation" "Small interfering RNA (siRNA) biogenesis" "ReactomePathway" "6" "8" "9" "89" "False" "" "685" "R-HSA-9696270" "LeafAnnotation" "RND2 GTPase cycle" "ReactomePathway" "29" "30" "42" "71" "False" "" "686" "R-HSA-8853383" "LeafAnnotation" "Lysosomal oligosaccharide catabolism" "ReactomePathway" "3" "3" "4" "75" "False" "" "687" "R-HSA-6803211" "LeafAnnotation" "TP53 Regulates Transcription of Death Receptors and Ligands" "ReactomePathway" "5" "5" "11" "45" "False" "" "688" "WP2431" "LeafAnnotation" "Spinal cord injury" "WikiPathway" "35" "38" "110" "35" "False" "" "689" "WP4752" "LeafAnnotation" "Base excision repair" "WikiPathway" "9" "9" "30" "30" "False" "" "690" "R-HSA-110357" "LeafAnnotation" "Displacement of DNA glycosylase by APEX1" "ReactomePathway" "2" "2" "7" "29" "False" "" "691" "R-HSA-110362" "LeafAnnotation" "POLB-Dependent Long Patch Base Excision Repair" "ReactomePathway" "4" "4" "8" "50" "False" "" "692" "R-HSA-110373" "IntermediateAnnotation" "Resolution of AP sites via the multiple-nucleotide patch replacement pathway" "ReactomePathway" "1" "1" "2" "50" "False" "" "693" "R-HSA-73930" "LeafAnnotation" "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" "ReactomePathway" "1" "1" "2" "50" "False" "" "694" "R-HSA-73933" "IntermediateAnnotation" "Resolution of Abasic Sites (AP sites)" "ReactomePathway" "1" "1" "1" "100" "False" "" "695" "R-HSA-9768919" "IntermediateAnnotation" "NPAS4 regulates expression of target genes" "ReactomePathway" "4" "5" "21" "24" "False" "" "696" "WP3668" "LeafAnnotation" "Hypothesized pathways in pathogenesis of cardiovascular disease" "WikiPathway" "15" "17" "25" "68" "False" "" "697" "WP3678" "LeafAnnotation" "Amplification and expansion of oncogenic pathways as metastatic traits" "WikiPathway" "6" "6" "16" "38" "False" "" "698" "WP197" "LeafAnnotation" "Cholesterol biosynthesis pathway" "WikiPathway" "14" "14" "15" "93" "False" "" "699" "WP1982" "LeafAnnotation" "Sterol regulatory element-binding proteins (SREBP) signaling" "WikiPathway" "41" "43" "68" "63" "False" "" "700" "WP43" "LeafAnnotation" "Oxidation by cytochrome P450" "WikiPathway" "10" "10" "61" "16" "False" "" "701" "WP4718" "LeafAnnotation" "Cholesterol metabolism with Bloch and Kandutsch-Russell pathways" "WikiPathway" "30" "31" "47" "66" "False" "" "702" "WP4804" "LeafAnnotation" "Cholesterol biosynthesis with skeletal dysplasias" "WikiPathway" "6" "6" "7" "86" "False" "" "703" "WP5193" "LeafAnnotation" "Cholesterol synthesis disorders" "WikiPathway" "16" "16" "18" "89" "False" "" "704" "WP702" "LeafAnnotation" "Metapathway biotransformation Phase I and II" "WikiPathway" "40" "46" "180" "26" "False" "" "705" "R-HSA-211976" "IntermediateAnnotation" "Endogenous sterols" "ReactomePathway" "6" "6" "25" "24" "False" "" "706" "R-HSA-191273" "IntermediateAnnotation" "Cholesterol biosynthesis" "ReactomePathway" "19" "20" "23" "87" "False" "" "707" "R-HSA-445355" "LeafAnnotation" "Smooth Muscle Contraction" "ReactomePathway" "25" "30" "43" "70" "False" "" "708" "R-HSA-9013409" "LeafAnnotation" "RHOJ GTPase cycle" "ReactomePathway" "37" "43" "54" "80" "False" "" "709" "R-HSA-9013507" "IntermediateAnnotation" "NOTCH3 Activation and Transmission of Signal to the Nucleus" "ReactomePathway" "10" "14" "23" "61" "False" "" "710" "R-HSA-9013420" "LeafAnnotation" "RHOU GTPase cycle" "ReactomePathway" "31" "33" "39" "85" "False" "" "711" "WP2878" "LeafAnnotation" "PPAR-alpha pathway" "WikiPathway" "13" "13" "26" "50" "False" "" "712" "R-HSA-200425" "LeafAnnotation" "Carnitine metabolism" "ReactomePathway" "5" "8" "14" "57" "False" "" "713" "R-HSA-9013418" "LeafAnnotation" "RHOBTB2 GTPase cycle" "ReactomePathway" "22" "22" "23" "96" "False" "" "714" "WP524" "LeafAnnotation" "G13 signaling pathway" "WikiPathway" "23" "23" "38" "61" "False" "" "715" "R-HSA-6811555" "LeafAnnotation" "PI5P Regulates TP53 Acetylation" "ReactomePathway" "5" "6" "9" "67" "False" "" "716" "R-HSA-8847453" "LeafAnnotation" "Synthesis of PIPs in the nucleus" "ReactomePathway" "4" "4" "4" "100" "False" "" "717" "WP5233" "LeafAnnotation" "Arsenic metabolism and reactive oxygen species generation" "WikiPathway" "10" "10" "11" "91" "False" "" "718" "R-HSA-8950505" "LeafAnnotation" "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" "ReactomePathway" "29" "31" "36" "86" "False" "" "719" "R-HSA-156590" "IntermediateAnnotation" "Glutathione conjugation" "ReactomePathway" "13" "15" "24" "62" "False" "" "720" "R-HSA-196836" "LeafAnnotation" "Vitamin C (ascorbate) metabolism" "ReactomePathway" "5" "5" "7" "71" "False" "" "721" "R-HSA-156581" "LeafAnnotation" "Methylation" "ReactomePathway" "9" "9" "14" "64" "False" "" "722" "R-HSA-429958" "LeafAnnotation" "mRNA decay by 3' to 5' exoribonuclease" "ReactomePathway" "14" "14" "16" "88" "False" "" "723" "R-HSA-9026762" "LeafAnnotation" "Biosynthesis of maresin conjugates in tissue regeneration (MCTR)" "ReactomePathway" "0" "1" "2" "50" "False" "" "724" "WP2359" "LeafAnnotation" "Parkin-ubiquitin proteasomal system pathway" "WikiPathway" "50" "56" "69" "81" "False" "" "725" "WP2291" "LeafAnnotation" "Deregulation of Rab and Rab effector genes in bladder cancer" "WikiPathway" "4" "4" "15" "27" "False" "" "726" "R-HSA-9758274" "IntermediateAnnotation" "Regulation of NF-kappa B signaling" "ReactomePathway" "7" "11" "18" "61" "False" "" "727" "R-HSA-140342" "LeafAnnotation" "Apoptosis induced DNA fragmentation" "ReactomePathway" "9" "12" "13" "92" "False" "" "728" "R-HSA-2559584" "LeafAnnotation" "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" "ReactomePathway" "9" "12" "16" "75" "False" "" "729" "WP4148" "LeafAnnotation" "Splicing factor NOVA regulated synaptic proteins" "WikiPathway" "23" "25" "42" "60" "False" "" "730" "R-HSA-373753" "LeafAnnotation" "Nephrin family interactions" "ReactomePathway" "16" "18" "22" "82" "False" "" "731" "R-HSA-212676" "LeafAnnotation" "Dopamine Neurotransmitter Release Cycle" "ReactomePathway" "8" "10" "22" "45" "False" "" "732" "WP5050" "LeafAnnotation" "TCA cycle in senescence" "WikiPathway" "7" "8" "10" "80" "False" "" "733" "R-HSA-72165" "LeafAnnotation" "mRNA Splicing - Minor Pathway" "ReactomePathway" "35" "36" "50" "72" "False" "" "734" "WP545" "LeafAnnotation" "Complement activation" "WikiPathway" "9" "10" "21" "48" "False" "" "735" "WP558" "LeafAnnotation" "Complement and coagulation cascades" "WikiPathway" "28" "29" "60" "48" "False" "" "736" "R-HSA-166663" "IntermediateAnnotation" "Initial triggering of complement" "ReactomePathway" "7" "12" "75" "16" "False" "" "737" "R-HSA-166662" "IntermediateAnnotation" "Lectin pathway of complement activation" "ReactomePathway" "3" "3" "7" "43" "False" "" "738" "R-HSA-2855086" "LeafAnnotation" "Ficolins bind to repetitive carbohydrate structures on the target cell surface" "ReactomePathway" "1" "1" "4" "25" "False" "" "739" "R-HSA-3000480" "LeafAnnotation" "Scavenging by Class A Receptors" "ReactomePathway" "11" "11" "18" "61" "False" "" "740" "R-HSA-112382" "LeafAnnotation" "Formation of RNA Pol II elongation complex" "ReactomePathway" "41" "41" "58" "71" "False" "" "741" "R-HSA-113418" "LeafAnnotation" "Formation of the Early Elongation Complex" "ReactomePathway" "26" "26" "33" "79" "False" "" "742" "R-HSA-167152" "LeafAnnotation" "Formation of HIV elongation complex in the absence of HIV Tat" "ReactomePathway" "34" "34" "45" "76" "False" "" "743" "R-HSA-167158" "LeafAnnotation" "Formation of the HIV-1 Early Elongation Complex" "ReactomePathway" "26" "26" "33" "79" "False" "" "744" "R-HSA-167200" "LeafAnnotation" "Formation of HIV-1 elongation complex containing HIV-1 Tat" "ReactomePathway" "33" "33" "43" "77" "False" "" "745" "R-HSA-167246" "IntermediateAnnotation" "Tat-mediated elongation of the HIV-1 transcript" "ReactomePathway" "31" "31" "41" "76" "False" "" "746" "R-HSA-674695" "LeafAnnotation" "RNA Polymerase II Pre-transcription Events" "ReactomePathway" "46" "46" "81" "57" "False" "" "747" "R-HSA-6796648" "LeafAnnotation" "TP53 Regulates Transcription of DNA Repair Genes" "ReactomePathway" "35" "35" "62" "56" "False" "" "748" "R-HSA-75955" "IntermediateAnnotation" "RNA Polymerase II Transcription Elongation" "ReactomePathway" "39" "39" "56" "70" "False" "" "749" "R-HSA-167161" "LeafAnnotation" "HIV Transcription Initiation" "ReactomePathway" "23" "23" "47" "49" "False" "" "750" "R-HSA-167162" "LeafAnnotation" "RNA Polymerase II HIV Promoter Escape" "ReactomePathway" "23" "23" "47" "49" "False" "" "751" "R-HSA-167172" "IntermediateAnnotation" "Transcription of the HIV genome" "ReactomePathway" "23" "23" "47" "49" "False" "" "752" "R-HSA-73776" "LeafAnnotation" "RNA Polymerase II Promoter Escape" "ReactomePathway" "23" "23" "47" "49" "False" "" "753" "R-HSA-73779" "LeafAnnotation" "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" "ReactomePathway" "23" "23" "47" "49" "False" "" "754" "R-HSA-75953" "LeafAnnotation" "RNA Polymerase II Transcription Initiation" "ReactomePathway" "23" "23" "47" "49" "False" "" "755" "R-HSA-76042" "IntermediateAnnotation" "RNA Polymerase II Transcription Initiation And Promoter Clearance" "ReactomePathway" "23" "23" "47" "49" "False" "" "756" "R-HSA-73762" "LeafAnnotation" "RNA Polymerase I Transcription Initiation" "ReactomePathway" "29" "31" "47" "66" "False" "" "757" "R-HSA-73863" "LeafAnnotation" "RNA Polymerase I Transcription Termination" "ReactomePathway" "20" "20" "31" "65" "False" "" "758" "R-HSA-6781823" "LeafAnnotation" "Formation of TC-NER Pre-Incision Complex" "ReactomePathway" "38" "41" "53" "77" "False" "" "759" "R-HSA-6781827" "IntermediateAnnotation" "Transcription-Coupled Nucleotide Excision Repair (TC-NER)" "ReactomePathway" "29" "32" "44" "73" "False" "" "760" "R-HSA-5696395" "LeafAnnotation" "Formation of Incision Complex in GG-NER" "ReactomePathway" "25" "28" "43" "65" "False" "" "761" "R-HSA-74217" "LeafAnnotation" "Purine salvage" "ReactomePathway" "10" "10" "12" "83" "False" "" "762" "WP2369" "LeafAnnotation" "Histone modifications" "WikiPathway" "10" "12" "44" "27" "False" "" "763" "R-HSA-182971" "LeafAnnotation" "EGFR downregulation" "ReactomePathway" "16" "20" "30" "67" "False" "" "764" "R-HSA-6807004" "IntermediateAnnotation" "Negative regulation of MET activity" "ReactomePathway" "12" "16" "20" "80" "False" "" "765" "R-HSA-8875360" "LeafAnnotation" "InlB-mediated entry of Listeria monocytogenes into host cell" "ReactomePathway" "8" "12" "14" "86" "False" "" "766" "WP4722" "LeafAnnotation" "Glycerolipids and glycerophospholipids" "WikiPathway" "9" "9" "22" "41" "False" "" "767" "WP5053" "LeafAnnotation" "Development of ureteric collection system" "WikiPathway" "15" "17" "59" "29" "False" "" "768" "WP4290" "LeafAnnotation" "Metabolic reprogramming in colon cancer" "WikiPathway" "40" "41" "42" "98" "False" "" "769" "WP4920" "LeafAnnotation" "Mitochondrial complex II assembly" "WikiPathway" "3" "3" "8" "38" "False" "" "770" "WP4698" "LeafAnnotation" "Vitamin D-sensitive calcium signaling in depression" "WikiPathway" "14" "14" "33" "42" "False" "" "771" "R-HSA-5578775" "LeafAnnotation" "Ion homeostasis" "ReactomePathway" "24" "29" "52" "56" "False" "" "772" "R-HSA-936837" "LeafAnnotation" "Ion transport by P-type ATPases" "ReactomePathway" "27" "33" "54" "61" "False" "" "773" "R-HSA-418359" "LeafAnnotation" "Reduction of cytosolic Ca++ levels" "ReactomePathway" "7" "9" "11" "82" "False" "" "774" "WP474" "LeafAnnotation" "Endochondral ossification" "WikiPathway" "21" "23" "63" "37" "False" "" "775" "WP4808" "LeafAnnotation" "Endochondral ossification with skeletal dysplasias" "WikiPathway" "21" "23" "63" "37" "False" "" "776" "WP5083" "LeafAnnotation" "Neuroinflammation and glutamatergic signaling" "WikiPathway" "51" "58" "139" "42" "False" "" "777" "R-HSA-210500" "LeafAnnotation" "Glutamate Neurotransmitter Release Cycle" "ReactomePathway" "8" "10" "23" "43" "False" "" "778" "R-HSA-352230" "LeafAnnotation" "Amino acid transport across the plasma membrane" "ReactomePathway" "11" "11" "32" "34" "False" "" "779" "WP3414" "LeafAnnotation" "Initiation of transcription and translation elongation at the HIV-1 LTR" "WikiPathway" "17" "19" "32" "59" "False" "" "780" "R-HSA-167238" "LeafAnnotation" "Pausing and recovery of Tat-mediated HIV elongation" "ReactomePathway" "22" "22" "31" "71" "False" "" "781" "R-HSA-167242" "LeafAnnotation" "Abortive elongation of HIV-1 transcript in the absence of Tat" "ReactomePathway" "17" "17" "23" "74" "False" "" "782" "R-HSA-167243" "LeafAnnotation" "Tat-mediated HIV elongation arrest and recovery" "ReactomePathway" "22" "22" "31" "71" "False" "" "783" "R-HSA-167287" "LeafAnnotation" "HIV elongation arrest and recovery" "ReactomePathway" "23" "23" "33" "70" "False" "" "784" "R-HSA-167290" "LeafAnnotation" "Pausing and recovery of HIV elongation" "ReactomePathway" "23" "23" "33" "70" "False" "" "785" "R-HSA-6807505" "LeafAnnotation" "RNA polymerase II transcribes snRNA genes" "ReactomePathway" "37" "37" "74" "50" "False" "" "786" "R-HSA-1268020" "LeafAnnotation" "Mitochondrial protein import" "ReactomePathway" "40" "40" "63" "63" "False" "" "787" "WP5223" "LeafAnnotation" "2q21.1 copy number variation syndrome" "WikiPathway" "4" "7" "16" "44" "False" "" "788" "R-HSA-437239" "LeafAnnotation" "Recycling pathway of L1" "ReactomePathway" "32" "42" "47" "89" "False" "" "789" "R-HSA-190840" "LeafAnnotation" "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" "ReactomePathway" "12" "19" "19" "100" "False" "" "790" "R-HSA-190861" "IntermediateAnnotation" "Gap junction assembly" "ReactomePathway" "12" "19" "37" "51" "False" "" "791" "R-HSA-3371497" "LeafAnnotation" "HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand" "ReactomePathway" "40" "47" "54" "87" "False" "" "792" "R-HSA-389960" "LeafAnnotation" "Formation of tubulin folding intermediates by CCT/TriC" "ReactomePathway" "19" "25" "25" "100" "False" "" "793" "R-HSA-389977" "LeafAnnotation" "Post-chaperonin tubulin folding pathway" "ReactomePathway" "16" "22" "22" "100" "False" "" "794" "R-HSA-5617833" "IntermediateAnnotation" "Cilium Assembly" "ReactomePathway" "11" "18" "20" "90" "False" "" "795" "R-HSA-5626467" "LeafAnnotation" "RHO GTPases activate IQGAPs" "ReactomePathway" "20" "28" "30" "93" "False" "" "796" "R-HSA-6811436" "LeafAnnotation" "COPI-independent Golgi-to-ER retrograde traffic" "ReactomePathway" "40" "47" "51" "92" "False" "" "797" "R-HSA-8955332" "LeafAnnotation" "Carboxyterminal post-translational modifications of tubulin" "ReactomePathway" "12" "19" "45" "42" "False" "" "798" "R-HSA-9619483" "LeafAnnotation" "Activation of AMPK downstream of NMDARs" "ReactomePathway" "14" "23" "26" "88" "False" "" "799" "R-HSA-9646399" "LeafAnnotation" "Aggrephagy" "ReactomePathway" "27" "37" "43" "86" "False" "" "800" "R-HSA-9013405" "LeafAnnotation" "RHOD GTPase cycle" "ReactomePathway" "38" "40" "50" "80" "False" "" "801" "R-HSA-9035034" "LeafAnnotation" "RHOF GTPase cycle" "ReactomePathway" "29" "31" "41" "76" "False" "" "802" "R-HSA-9013407" "LeafAnnotation" "RHOH GTPase cycle" "ReactomePathway" "28" "31" "37" "84" "False" "" "803" "R-HSA-425381" "LeafAnnotation" "Bicarbonate transporters" "ReactomePathway" "4" "4" "10" "40" "False" "" "804" "R-HSA-9614657" "LeafAnnotation" "FOXO-mediated transcription of cell death genes" "ReactomePathway" "2" "2" "16" "12" "False" "" "805" "R-HSA-380994" "LeafAnnotation" "ATF4 activates genes in response to endoplasmic reticulum stress" "ReactomePathway" "16" "16" "27" "59" "False" "" "806" "R-HSA-381183" "LeafAnnotation" "ATF6 (ATF6-alpha) activates chaperone genes" "ReactomePathway" "5" "5" "9" "56" "False" "" "807" "R-HSA-9696264" "LeafAnnotation" "RND3 GTPase cycle" "ReactomePathway" "28" "30" "41" "73" "False" "" "808" "R-HSA-9696273" "LeafAnnotation" "RND1 GTPase cycle" "ReactomePathway" "25" "27" "42" "64" "False" "" "809" "R-HSA-432722" "LeafAnnotation" "Golgi Associated Vesicle Biogenesis" "ReactomePathway" "41" "44" "53" "83" "False" "" "810" "R-HSA-2022090" "IntermediateAnnotation" "Assembly of collagen fibrils and other multimeric structures" "ReactomePathway" "22" "23" "48" "48" "False" "" "811" "R-HSA-8939242" "LeafAnnotation" "RUNX1 regulates transcription of genes involved in differentiation of keratinocytes" "ReactomePathway" "3" "3" "8" "38" "False" "" "812" "R-HSA-1592389" "LeafAnnotation" "Activation of Matrix Metalloproteinases" "ReactomePathway" "10" "11" "33" "33" "False" "" "813" "WP2805" "LeafAnnotation" "exRNA mechanism of action and biogenesis" "WikiPathway" "4" "4" "6" "67" "False" "" "814" "WP4844" "LeafAnnotation" "Influence of laminopathies on Wnt signaling" "WikiPathway" "16" "17" "34" "50" "False" "" "815" "WP4879" "LeafAnnotation" "Overlap between signal transduction pathways contributing to LMNA laminopathies" "WikiPathway" "25" "28" "53" "53" "False" "" "816" "R-HSA-8986944" "IntermediateAnnotation" "Transcriptional Regulation by MECP2" "ReactomePathway" "5" "7" "16" "44" "False" "" "817" "R-HSA-4086398" "LeafAnnotation" "Ca2+ pathway" "ReactomePathway" "25" "31" "58" "53" "False" "" "818" "R-HSA-9022692" "LeafAnnotation" "Regulation of MECP2 expression and activity" "ReactomePathway" "15" "21" "29" "72" "False" "" "819" "R-HSA-9029569" "LeafAnnotation" "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" "ReactomePathway" "11" "15" "36" "42" "False" "" "820" "R-HSA-203927" "LeafAnnotation" "MicroRNA (miRNA) biogenesis" "ReactomePathway" "14" "16" "24" "67" "False" "" "821" "R-HSA-8943723" "IntermediateAnnotation" "Regulation of PTEN mRNA translation" "ReactomePathway" "3" "5" "9" "56" "False" "" "822" "R-HSA-9768778" "IntermediateAnnotation" "Regulation of NPAS4 mRNA translation" "ReactomePathway" "3" "5" "9" "56" "False" "" "823" "R-HSA-426496" "LeafAnnotation" "Post-transcriptional silencing by small RNAs" "ReactomePathway" "2" "4" "7" "57" "False" "" "824" "R-HSA-8948700" "LeafAnnotation" "Competing endogenous RNAs (ceRNAs) regulate PTEN translation" "ReactomePathway" "3" "5" "8" "62" "False" "" "825" "WP138" "LeafAnnotation" "Androgen receptor signaling pathway" "WikiPathway" "48" "49" "89" "55" "False" "" "826" "WP2853" "LeafAnnotation" "Endoderm differentiation" "WikiPathway" "19" "21" "66" "32" "False" "" "827" "R-HSA-917937" "IntermediateAnnotation" "Iron uptake and transport" "ReactomePathway" "13" "16" "26" "62" "False" "" "828" "R-HSA-2565942" "LeafAnnotation" "Regulation of PLK1 Activity at G2/M Transition" "ReactomePathway" "39" "44" "83" "53" "False" "" "829" "R-HSA-380259" "LeafAnnotation" "Loss of Nlp from mitotic centrosomes" "ReactomePathway" "32" "34" "67" "51" "False" "" "830" "R-HSA-380284" "IntermediateAnnotation" "Loss of proteins required for interphase microtubule organization from the centrosome" "ReactomePathway" "32" "34" "67" "51" "False" "" "831" "R-HSA-5620912" "LeafAnnotation" "Anchoring of the basal body to the plasma membrane" "ReactomePathway" "36" "39" "95" "41" "False" "" "832" "R-HSA-8854518" "LeafAnnotation" "AURKA Activation by TPX2" "ReactomePathway" "34" "36" "69" "52" "False" "" "833" "WP2267" "LeafAnnotation" "Synaptic vesicle pathway" "WikiPathway" "27" "27" "51" "53" "False" "" "834" "WP383" "LeafAnnotation" "Striated muscle contraction pathway" "WikiPathway" "16" "21" "38" "55" "False" "" "835" "R-HSA-5625900" "LeafAnnotation" "RHO GTPases activate CIT" "ReactomePathway" "14" "15" "19" "79" "False" "" "836" "R-HSA-3928663" "LeafAnnotation" "EPHA-mediated growth cone collapse" "ReactomePathway" "14" "20" "28" "71" "False" "" "837" "R-HSA-416572" "LeafAnnotation" "Sema4D induced cell migration and growth-cone collapse" "ReactomePathway" "16" "16" "20" "80" "False" "" "838" "R-HSA-5627117" "LeafAnnotation" "RHO GTPases Activate ROCKs" "ReactomePathway" "15" "17" "19" "89" "False" "" "839" "R-HSA-5627123" "LeafAnnotation" "RHO GTPases activate PAKs" "ReactomePathway" "17" "19" "20" "95" "False" "" "840" "R-HSA-3928665" "LeafAnnotation" "EPH-ephrin mediated repulsion of cells" "ReactomePathway" "27" "36" "50" "72" "False" "" "841" "R-HSA-2682334" "IntermediateAnnotation" "EPH-Ephrin signaling" "ReactomePathway" "7" "15" "25" "60" "False" "" "842" "R-HSA-162658" "LeafAnnotation" "Golgi Cisternae Pericentriolar Stack Reorganization" "ReactomePathway" "10" "10" "13" "77" "False" "" "843" "WP716" "LeafAnnotation" "Vitamin A and carotenoid metabolism" "WikiPathway" "5" "10" "43" "23" "False" "" "844" "R-HSA-2453902" "IntermediateAnnotation" "The canonical retinoid cycle in rods (twilight vision)" "ReactomePathway" "2" "3" "22" "14" "False" "" "845" "R-HSA-5365859" "LeafAnnotation" "RA biosynthesis pathway" "ReactomePathway" "6" "12" "22" "55" "False" "" "846" "R-HSA-9031628" "LeafAnnotation" "NGF-stimulated transcription" "ReactomePathway" "8" "9" "39" "23" "False" "" "847" "R-HSA-446388" "LeafAnnotation" "Regulation of cytoskeletal remodeling and cell spreading by IPP complex components" "ReactomePathway" "6" "6" "8" "75" "False" "" "848" "R-HSA-446353" "IntermediateAnnotation" "Cell-extracellular matrix interactions" "ReactomePathway" "11" "11" "12" "92" "False" "" "849" "WP3893" "LeafAnnotation" "Development and heterogeneity of the ILC family" "WikiPathway" "0" "1" "32" "3" "False" "" "850" "WP2363" "LeafAnnotation" "Gastric cancer network 2" "WikiPathway" "14" "15" "32" "47" "False" "" "851" "WP2446" "LeafAnnotation" "Retinoblastoma gene in cancer" "WikiPathway" "39" "43" "87" "49" "False" "" "852" "R-HSA-1362277" "LeafAnnotation" "Transcription of E2F targets under negative control by DREAM complex" "ReactomePathway" "5" "5" "19" "26" "False" "" "853" "WP438" "LeafAnnotation" "Non-homologous end joining" "WikiPathway" "5" "5" "10" "50" "False" "" "854" "R-HSA-1834949" "IntermediateAnnotation" "Cytosolic sensors of pathogen-associated DNA" "ReactomePathway" "8" "8" "22" "36" "False" "" "855" "R-HSA-5693571" "LeafAnnotation" "Nonhomologous End-Joining (NHEJ)" "ReactomePathway" "20" "34" "51" "67" "False" "" "856" "R-HSA-164843" "LeafAnnotation" "2-LTR circle formation" "ReactomePathway" "7" "7" "7" "100" "False" "" "857" "R-HSA-3270619" "LeafAnnotation" "IRF3-mediated induction of type I IFN" "ReactomePathway" "10" "10" "13" "77" "False" "" "858" "WP3407" "LeafAnnotation" "FTO obesity variant mechanism" "WikiPathway" "2" "2" "8" "25" "False" "" "859" "R-HSA-73943" "IntermediateAnnotation" "Reversal of alkylation damage by DNA dioxygenases" "ReactomePathway" "2" "2" "2" "100" "False" "" "860" "R-HSA-9679191" "LeafAnnotation" "Potential therapeutics for SARS" "ReactomePathway" "54" "62" "153" "41" "False" "" "861" "R-HSA-210991" "LeafAnnotation" "Basigin interactions" "ReactomePathway" "16" "16" "25" "64" "False" "" "862" "WP2873" "LeafAnnotation" "Aryl hydrocarbon receptor pathway" "WikiPathway" "15" "16" "42" "38" "False" "" "863" "R-HSA-388844" "LeafAnnotation" "Receptor-type tyrosine-protein phosphatases" "ReactomePathway" "4" "8" "19" "42" "False" "" "864" "R-HSA-162588" "LeafAnnotation" "Budding and maturation of HIV virion" "ReactomePathway" "22" "25" "28" "89" "False" "" "865" "R-HSA-917729" "LeafAnnotation" "Endosomal Sorting Complex Required For Transport (ESCRT)" "ReactomePathway" "23" "26" "31" "84" "False" "" "866" "R-HSA-9615710" "LeafAnnotation" "Late endosomal microautophagy" "ReactomePathway" "22" "26" "34" "76" "False" "" "867" "R-HSA-5620971" "LeafAnnotation" "Pyroptosis" "ReactomePathway" "14" "14" "27" "52" "False" "" "868" "R-HSA-9679504" "IntermediateAnnotation" "Translation of Replicase and Assembly of the Replication Transcription Complex" "ReactomePathway" "10" "11" "13" "85" "False" "" "869" "R-HSA-9694676" "IntermediateAnnotation" "Translation of Replicase and Assembly of the Replication Transcription Complex" "ReactomePathway" "10" "11" "13" "85" "False" "" "870" "WP236" "LeafAnnotation" "Adipogenesis" "WikiPathway" "39" "41" "130" "32" "False" "" "871" "WP272" "LeafAnnotation" "Blood clotting cascade" "WikiPathway" "14" "14" "21" "67" "False" "" "872" "WP3614" "LeafAnnotation" "Photodynamic therapy-induced HIF-1 survival signaling" "WikiPathway" "19" "20" "35" "57" "False" "" "873" "WP3982" "LeafAnnotation" "miRNA regulation of p53 pathway in prostate cancer" "WikiPathway" "8" "8" "25" "32" "False" "" "874" "WP4816" "LeafAnnotation" "TGF-beta receptor signaling in skeletal dysplasias" "WikiPathway" "18" "20" "58" "34" "False" "" "875" "WP4969" "LeafAnnotation" "RAS and bradykinin pathways in COVID-19" "WikiPathway" "8" "8" "26" "31" "False" "" "876" "WP560" "LeafAnnotation" "TGF-beta receptor signaling" "WikiPathway" "16" "18" "54" "33" "False" "" "877" "R-HSA-2173796" "LeafAnnotation" "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" "ReactomePathway" "14" "19" "36" "53" "False" "" "878" "R-HSA-75205" "LeafAnnotation" "Dissolution of Fibrin Clot" "ReactomePathway" "10" "10" "12" "83" "False" "" "879" "WP2007" "LeafAnnotation" "Iron metabolism in placenta" "WikiPathway" "7" "8" "11" "73" "False" "" "880" "WP3286" "LeafAnnotation" "Copper homeostasis" "WikiPathway" "23" "26" "51" "51" "False" "" "881" "WP4313" "LeafAnnotation" "Ferroptosis" "WikiPathway" "41" "45" "61" "74" "False" "" "882" "R-HSA-6803204" "LeafAnnotation" "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" "ReactomePathway" "7" "7" "20" "35" "False" "" "883" "WP325" "LeafAnnotation" "Triacylglyceride synthesis" "WikiPathway" "9" "10" "24" "42" "False" "" "884" "R-HSA-75896" "LeafAnnotation" "Plasmalogen biosynthesis" "ReactomePathway" "3" "3" "3" "100" "False" "" "885" "R-HSA-9033500" "LeafAnnotation" "TYSND1 cleaves peroxisomal proteins" "ReactomePathway" "5" "5" "7" "71" "False" "" "886" "WP2880" "LeafAnnotation" "Glucocorticoid receptor pathway" "WikiPathway" "19" "22" "69" "32" "False" "" "887" "R-HSA-499943" "LeafAnnotation" "Interconversion of nucleotide di- and triphosphates" "ReactomePathway" "20" "21" "28" "75" "False" "" "888" "R-HSA-9748787" "LeafAnnotation" "Azathioprine ADME" "ReactomePathway" "14" "14" "23" "61" "False" "" "889" "R-HSA-9755088" "IntermediateAnnotation" "Ribavirin ADME" "ReactomePathway" "9" "9" "11" "82" "False" "" "890" "R-HSA-430039" "LeafAnnotation" "mRNA decay by 5' to 3' exoribonuclease" "ReactomePathway" "10" "10" "15" "67" "False" "" "891" "R-HSA-390522" "LeafAnnotation" "Striated Muscle Contraction" "ReactomePathway" "14" "19" "36" "53" "False" "" "892" "WP4656" "LeafAnnotation" "Joubert syndrome" "WikiPathway" "22" "23" "71" "32" "False" "" "893" "WP4803" "LeafAnnotation" "Ciliopathies" "WikiPathway" "36" "38" "181" "21" "False" "" "894" "WP5234" "LeafAnnotation" "Bardet-Biedl syndrome" "WikiPathway" "15" "17" "84" "20" "False" "" "895" "R-HSA-5624138" "LeafAnnotation" "Trafficking of myristoylated proteins to the cilium" "ReactomePathway" "3" "3" "5" "60" "False" "" "896" "R-HSA-5357905" "LeafAnnotation" "Regulation of TNFR1 signaling" "ReactomePathway" "22" "27" "45" "60" "False" "" "897" "WP3878" "LeafAnnotation" "ATM signaling in development and disease" "WikiPathway" "23" "24" "45" "53" "False" "" "898" "R-HSA-9013422" "LeafAnnotation" "RHOBTB1 GTPase cycle" "ReactomePathway" "20" "20" "23" "87" "False" "" "899" "R-HSA-1369062" "LeafAnnotation" "ABC transporters in lipid homeostasis" "ReactomePathway" "6" "6" "18" "33" "False" "" "900" "WP2436" "LeafAnnotation" "Dopamine metabolism" "WikiPathway" "8" "10" "13" "77" "False" "" "901" "WP2636" "LeafAnnotation" "Common pathways underlying drug addiction" "WikiPathway" "18" "25" "42" "60" "False" "" "902" "WP4249" "LeafAnnotation" "Hedgehog signaling pathway" "WikiPathway" "14" "21" "42" "50" "False" "" "903" "WP4941" "LeafAnnotation" "GPR143 in melanocytes and retinal pigment epithelium cells" "WikiPathway" "11" "14" "30" "47" "False" "" "904" "R-HSA-111931" "IntermediateAnnotation" "PKA-mediated phosphorylation of CREB" "ReactomePathway" "3" "4" "5" "80" "False" "" "905" "R-HSA-422356" "IntermediateAnnotation" "Regulation of insulin secretion" "ReactomePathway" "14" "16" "27" "59" "False" "" "906" "R-HSA-5621575" "LeafAnnotation" "CD209 (DC-SIGN) signaling" "ReactomePathway" "9" "13" "20" "65" "False" "" "907" "R-HSA-8963896" "LeafAnnotation" "HDL assembly" "ReactomePathway" "4" "5" "7" "71" "False" "" "908" "R-HSA-9010642" "LeafAnnotation" "ROBO receptors bind AKAP5" "ReactomePathway" "5" "6" "8" "75" "False" "" "909" "R-HSA-163358" "LeafAnnotation" "PKA-mediated phosphorylation of key metabolic factors" "ReactomePathway" "2" "3" "5" "60" "False" "" "910" "WP3941" "LeafAnnotation" "Oxidative damage response" "WikiPathway" "14" "15" "38" "39" "False" "" "911" "WP4493" "LeafAnnotation" "Cells and molecules involved in local acute inflammatory response" "WikiPathway" "6" "6" "17" "35" "False" "" "912" "WP5104" "LeafAnnotation" "Acquired partial lipodystrophy / Barraquer-Simons syndrome" "WikiPathway" "8" "8" "10" "80" "False" "" "913" "R-HSA-418594" "IntermediateAnnotation" "G alpha (i) signalling events" "ReactomePathway" "31" "38" "255" "15" "False" "" "914" "R-HSA-977606" "LeafAnnotation" "Regulation of Complement cascade" "ReactomePathway" "16" "21" "106" "20" "False" "" "915" "R-HSA-375276" "IntermediateAnnotation" "Peptide ligand-binding receptors" "ReactomePathway" "7" "7" "104" "7" "False" "" "916" "R-HSA-174577" "LeafAnnotation" "Activation of C3 and C5" "ReactomePathway" "3" "4" "7" "57" "False" "" "917" "R-HSA-166665" "LeafAnnotation" "Terminal pathway of complement" "ReactomePathway" "5" "5" "8" "62" "False" "" "918" "WP4153" "LeafAnnotation" "Degradation pathway of sphingolipids, including diseases" "WikiPathway" "10" "10" "10" "100" "False" "" "919" "WP4815" "LeafAnnotation" "Glycosaminoglycan degradation" "WikiPathway" "10" "10" "16" "62" "False" "" "920" "R-HSA-1660662" "LeafAnnotation" "Glycosphingolipid metabolism" "ReactomePathway" "27" "27" "43" "63" "False" "" "921" "R-HSA-2024101" "LeafAnnotation" "CS/DS degradation" "ReactomePathway" "7" "7" "13" "54" "False" "" "922" "R-HSA-2160916" "LeafAnnotation" "Hyaluronan uptake and degradation" "ReactomePathway" "6" "6" "11" "55" "False" "" "923" "R-HSA-2022857" "LeafAnnotation" "Keratan sulfate degradation" "ReactomePathway" "5" "5" "12" "42" "False" "" "924" "R-HSA-3656234" "LeafAnnotation" "Defective HEXA causes GM2G1" "ReactomePathway" "1" "1" "1" "100" "False" "" "925" "WP4884" "LeafAnnotation" "Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex" "WikiPathway" "3" "5" "22" "23" "False" "" "926" "WP2064" "LeafAnnotation" "Neural crest differentiation" "WikiPathway" "20" "25" "99" "25" "False" "" "927" "WP3996" "LeafAnnotation" "Ethanol effects on histone modifications" "WikiPathway" "8" "14" "29" "48" "False" "" "928" "R-HSA-2644606" "LeafAnnotation" "Constitutive Signaling by NOTCH1 PEST Domain Mutants" "ReactomePathway" "19" "25" "56" "45" "False" "" "929" "R-HSA-2894862" "LeafAnnotation" "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" "ReactomePathway" "19" "25" "56" "45" "False" "" "930" "R-HSA-2122947" "LeafAnnotation" "NOTCH1 Intracellular Domain Regulates Transcription" "ReactomePathway" "13" "19" "46" "41" "False" "" "931" "R-HSA-350054" "LeafAnnotation" "Notch-HLH transcription pathway" "ReactomePathway" "11" "13" "28" "46" "False" "" "932" "WP4900" "LeafAnnotation" "Purinergic signaling" "WikiPathway" "6" "12" "35" "34" "False" "" "933" "R-HSA-418597" "LeafAnnotation" "G alpha (z) signalling events" "ReactomePathway" "18" "25" "49" "51" "False" "" "934" "R-HSA-170670" "LeafAnnotation" "Adenylate cyclase inhibitory pathway" "ReactomePathway" "5" "8" "14" "57" "False" "" "935" "R-HSA-381771" "LeafAnnotation" "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" "ReactomePathway" "9" "10" "21" "48" "False" "" "936" "R-HSA-392170" "LeafAnnotation" "ADP signalling through P2Y purinoceptor 12" "ReactomePathway" "11" "12" "22" "55" "False" "" "937" "R-HSA-418555" "IntermediateAnnotation" "G alpha (s) signalling events" "ReactomePathway" "23" "28" "146" "19" "False" "" "938" "R-HSA-9717207" "LeafAnnotation" "Sensory perception of sweet, bitter, and umami (glutamate) taste" "ReactomePathway" "5" "6" "41" "15" "False" "" "939" "R-HSA-2206290" "LeafAnnotation" "MPS IV - Morquio syndrome A" "ReactomePathway" "1" "1" "1" "100" "False" "" "940" "WP1992" "LeafAnnotation" "Genes targeted by miRNAs in adipocytes" "WikiPathway" "5" "5" "12" "42" "False" "" "941" "WP2355" "LeafAnnotation" "Corticotropin-releasing hormone signaling pathway" "WikiPathway" "37" "47" "95" "49" "False" "" "942" "WP363" "LeafAnnotation" "Wnt signaling pathway" "WikiPathway" "24" "29" "50" "58" "False" "" "943" "WP4905" "LeafAnnotation" "1q21.1 copy number variation syndrome" "WikiPathway" "10" "12" "27" "44" "False" "" "944" "R-HSA-190704" "LeafAnnotation" "Oligomerization of connexins into connexons" "ReactomePathway" "1" "1" "3" "33" "False" "" "945" "R-HSA-190827" "LeafAnnotation" "Transport of connexins along the secretory pathway" "ReactomePathway" "1" "1" "3" "33" "False" "" "946" "R-HSA-190873" "IntermediateAnnotation" "Gap junction degradation" "ReactomePathway" "12" "12" "12" "100" "False" "" "947" "R-HSA-196025" "LeafAnnotation" "Formation of annular gap junctions" "ReactomePathway" "11" "11" "11" "100" "False" "" "948" "R-HSA-191650" "LeafAnnotation" "Regulation of gap junction activity" "ReactomePathway" "2" "2" "2" "100" "False" "" "949" "R-HSA-9705677" "LeafAnnotation" "SARS-CoV-2 targets PDZ proteins in cell-cell junction" "ReactomePathway" "3" "3" "5" "60" "False" "" "950" "R-HSA-6785807" "LeafAnnotation" "Interleukin-4 and Interleukin-13 signaling" "ReactomePathway" "29" "31" "110" "28" "False" "" "951" "R-HSA-2473224" "LeafAnnotation" "Antagonism of Activin by Follistatin" "ReactomePathway" "2" "2" "4" "50" "False" "" "952" "R-HSA-804914" "LeafAnnotation" "Transport of fatty acids" "ReactomePathway" "2" "2" "8" "25" "False" "" "953" "WP4788" "LeafAnnotation" "Autosomal recessive osteopetrosis pathways" "WikiPathway" "7" "7" "11" "64" "False" "" "954" "R-HSA-2672351" "IntermediateAnnotation" "Stimuli-sensing channels" "ReactomePathway" "17" "22" "76" "29" "False" "" "955" "WP3863" "LeafAnnotation" "T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection" "WikiPathway" "23" "29" "62" "47" "False" "" "956" "WP4875" "LeafAnnotation" "Disruption of postsynaptic signaling by CNV" "WikiPathway" "10" "13" "36" "36" "False" "" "957" "WP4906" "LeafAnnotation" "3q29 copy number variation syndrome" "WikiPathway" "22" "24" "62" "39" "False" "" "958" "R-HSA-8849932" "LeafAnnotation" "Synaptic adhesion-like molecules" "ReactomePathway" "6" "8" "21" "38" "False" "" "959" "R-HSA-399719" "IntermediateAnnotation" "Trafficking of AMPA receptors" "ReactomePathway" "6" "8" "17" "47" "False" "" "960" "R-HSA-447038" "LeafAnnotation" "NrCAM interactions" "ReactomePathway" "3" "4" "7" "57" "False" "" "961" "R-HSA-451308" "LeafAnnotation" "Activation of Ca-permeable Kainate Receptor" "ReactomePathway" "1" "3" "9" "33" "False" "" "962" "R-HSA-447043" "LeafAnnotation" "Neurofascin interactions" "ReactomePathway" "3" "3" "7" "43" "False" "" "963" "WP2875" "LeafAnnotation" "Constitutive androstane receptor pathway" "WikiPathway" "8" "8" "30" "27" "False" "" "964" "WP3651" "LeafAnnotation" "Pathways affected in adenoid cystic carcinoma" "WikiPathway" "20" "24" "60" "40" "False" "" "965" "WP4240" "LeafAnnotation" "Regulation of sister chromatid separation at the metaphase-anaphase transition" "WikiPathway" "6" "6" "15" "40" "False" "" "966" "WP4874" "LeafAnnotation" "CAMKK2 pathway" "WikiPathway" "22" "23" "33" "70" "False" "" "967" "WP5118" "LeafAnnotation" "SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome" "WikiPathway" "6" "6" "11" "55" "False" "" "968" "R-HSA-2468052" "LeafAnnotation" "Establishment of Sister Chromatid Cohesion" "ReactomePathway" "7" "7" "11" "64" "False" "" "969" "R-HSA-2470946" "LeafAnnotation" "Cohesin Loading onto Chromatin" "ReactomePathway" "8" "8" "10" "80" "False" "" "970" "R-HSA-163359" "IntermediateAnnotation" "Glucagon signaling in metabolic regulation" "ReactomePathway" "11" "13" "27" "48" "False" "" "971" "R-HSA-416476" "IntermediateAnnotation" "G alpha (q) signalling events" "ReactomePathway" "26" "31" "172" "18" "False" "" "972" "R-HSA-456926" "LeafAnnotation" "Thrombin signalling through proteinase activated receptors (PARs)" "ReactomePathway" "16" "18" "31" "58" "False" "" "973" "R-HSA-1296041" "LeafAnnotation" "Activation of G protein gated Potassium channels" "ReactomePathway" "10" "10" "29" "34" "False" "" "974" "R-HSA-202040" "LeafAnnotation" "G-protein activation" "ReactomePathway" "10" "11" "24" "46" "False" "" "975" "R-HSA-392851" "LeafAnnotation" "Prostacyclin signalling through prostacyclin receptor" "ReactomePathway" "9" "10" "20" "50" "False" "" "976" "R-HSA-400042" "LeafAnnotation" "Adrenaline,noradrenaline inhibits insulin secretion" "ReactomePathway" "13" "15" "28" "54" "False" "" "977" "R-HSA-418217" "LeafAnnotation" "G beta:gamma signalling through PLC beta" "ReactomePathway" "10" "10" "20" "50" "False" "" "978" "R-HSA-418592" "LeafAnnotation" "ADP signalling through P2Y purinoceptor 1" "ReactomePathway" "11" "12" "24" "50" "False" "" "979" "R-HSA-420092" "LeafAnnotation" "Glucagon-type ligand receptors" "ReactomePathway" "9" "10" "34" "29" "False" "" "980" "R-HSA-428930" "LeafAnnotation" "Thromboxane signalling through TP receptor" "ReactomePathway" "12" "13" "24" "54" "False" "" "981" "R-HSA-500657" "LeafAnnotation" "Presynaptic function of Kainate receptors" "ReactomePathway" "10" "10" "21" "48" "False" "" "982" "R-HSA-6814122" "LeafAnnotation" "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" "ReactomePathway" "22" "23" "38" "61" "False" "" "983" "R-HSA-8964315" "LeafAnnotation" "G beta:gamma signalling through BTK" "ReactomePathway" "8" "9" "18" "50" "False" "" "984" "R-HSA-8964616" "LeafAnnotation" "G beta:gamma signalling through CDC42" "ReactomePathway" "10" "11" "20" "55" "False" "" "985" "R-HSA-997272" "LeafAnnotation" "Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits" "ReactomePathway" "10" "10" "29" "34" "False" "" "986" "WP2371" "LeafAnnotation" "Parkinson's disease pathway" "WikiPathway" "18" "19" "38" "50" "False" "" "987" "WP2447" "LeafAnnotation" "Amyotrophic lateral sclerosis (ALS)" "WikiPathway" "22" "27" "35" "77" "False" "" "988" "WP314" "LeafAnnotation" "Fas ligand pathway and stress induction of heat shock proteins" "WikiPathway" "24" "25" "42" "60" "False" "" "989" "WP384" "LeafAnnotation" "Apoptosis modulation by HSP70" "WikiPathway" "13" "13" "20" "65" "False" "" "990" "WP4630" "LeafAnnotation" "Measles virus infection" "WikiPathway" "53" "61" "134" "46" "False" "" "991" "WP4838" "LeafAnnotation" "Regucalcin in proximal tubule epithelial kidney cells" "WikiPathway" "9" "12" "19" "63" "False" "" "992" "WP4864" "LeafAnnotation" "Host-pathogen interaction of human coronaviruses - apoptosis" "WikiPathway" "9" "9" "22" "41" "False" "" "993" "R-HSA-111459" "LeafAnnotation" "Activation of caspases through apoptosome-mediated cleavage" "ReactomePathway" "3" "3" "6" "50" "False" "" "994" "R-HSA-6803207" "LeafAnnotation" "TP53 Regulates Transcription of Caspase Activators and Caspases" "ReactomePathway" "4" "4" "12" "33" "False" "" "995" "WP1528" "LeafAnnotation" "Physiological and pathological hypertrophy of the heart" "WikiPathway" "14" "15" "24" "62" "False" "" "996" "WP2023" "LeafAnnotation" "Cell differentiation - expanded index" "WikiPathway" "2" "2" "19" "11" "False" "" "997" "WP2029" "LeafAnnotation" "Cell differentiation - index" "WikiPathway" "2" "2" "13" "15" "False" "" "998" "WP205" "LeafAnnotation" "IL-7 signaling pathway" "WikiPathway" "13" "15" "25" "60" "False" "" "999" "WP2112" "LeafAnnotation" "IL-17 signaling pathway" "WikiPathway" "14" "14" "32" "44" "False" "" "1000" "WP22" "LeafAnnotation" "IL-9 signaling pathway" "WikiPathway" "10" "11" "17" "65" "False" "" "1001" "WP2324" "LeafAnnotation" "AGE/RAGE pathway" "WikiPathway" "33" "37" "66" "56" "False" "" "1002" "WP2815" "LeafAnnotation" "Mammary gland development pathway - Involution (Stage 4 of 4)" "WikiPathway" "3" "3" "10" "30" "False" "" "1003" "WP2855" "LeafAnnotation" "Dopaminergic neurogenesis" "WikiPathway" "2" "3" "29" "10" "False" "" "1004" "WP2868" "LeafAnnotation" "TCA cycle nutrient use and invasiveness of ovarian cancer" "WikiPathway" "5" "5" "5" "100" "False" "" "1005" "WP2881" "LeafAnnotation" "Estrogen receptor pathway" "WikiPathway" "4" "4" "13" "31" "False" "" "1006" "WP3892" "LeafAnnotation" "Development of pulmonary dendritic cells and macrophage subsets" "WikiPathway" "2" "2" "13" "15" "False" "" "1007" "WP4298" "LeafAnnotation" "Acute viral myocarditis" "WikiPathway" "37" "41" "76" "54" "False" "" "1008" "WP4300" "LeafAnnotation" "Extracellular vesicles in the crosstalk of cardiac cells" "WikiPathway" "8" "8" "19" "42" "False" "" "1009" "WP4337" "LeafAnnotation" "ncRNAs involved in STAT3 signaling in hepatocellular carcinoma" "WikiPathway" "6" "6" "13" "46" "False" "" "1010" "WP4495" "LeafAnnotation" "IL-10 anti-inflammatory signaling pathway" "WikiPathway" "7" "7" "12" "58" "False" "" "1011" "WP4538" "LeafAnnotation" "Regulatory circuits of the STAT3 signaling pathway" "WikiPathway" "6" "6" "29" "21" "False" "" "1012" "WP4559" "LeafAnnotation" "Interactions between immune cells and microRNAs in tumor microenvironment" "WikiPathway" "8" "8" "27" "30" "False" "" "1013" "WP4829" "LeafAnnotation" "mBDNF and proBDNF regulation of GABA neurotransmission" "WikiPathway" "11" "14" "37" "38" "False" "" "1014" "WP5097" "LeafAnnotation" "CCL18 signaling pathway" "WikiPathway" "44" "50" "109" "46" "False" "" "1015" "WP5130" "LeafAnnotation" "Th17 cell differentiation pathway" "WikiPathway" "15" "18" "68" "26" "False" "" "1016" "WP5198" "LeafAnnotation" "Inflammatory bowel disease signaling" "WikiPathway" "6" "7" "42" "17" "False" "" "1017" "WP5265" "LeafAnnotation" "Neurogenesis regulation in the olfactory epithelium" "WikiPathway" "20" "21" "57" "37" "False" "" "1018" "WP581" "LeafAnnotation" "EPO receptor signaling" "WikiPathway" "13" "14" "26" "54" "False" "" "1019" "WP61" "LeafAnnotation" "Notch signaling pathway" "WikiPathway" "30" "33" "61" "54" "False" "" "1020" "WP733" "LeafAnnotation" "Serotonin receptor 2 and STAT3 signaling" "WikiPathway" "2" "2" "4" "50" "False" "" "1021" "R-HSA-201556" "IntermediateAnnotation" "Signaling by ALK" "ReactomePathway" "4" "5" "16" "31" "False" "" "1022" "R-HSA-9670439" "LeafAnnotation" "Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants" "ReactomePathway" "7" "12" "17" "71" "False" "" "1023" "R-HSA-9673767" "LeafAnnotation" "Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants" "ReactomePathway" "6" "7" "10" "70" "False" "" "1024" "R-HSA-9673770" "LeafAnnotation" "Signaling by PDGFRA extracellular domain mutants" "ReactomePathway" "6" "7" "10" "70" "False" "" "1025" "R-HSA-6783783" "LeafAnnotation" "Interleukin-10 signaling" "ReactomePathway" "7" "8" "45" "18" "False" "" "1026" "R-HSA-982772" "LeafAnnotation" "Growth hormone receptor signaling" "ReactomePathway" "8" "8" "23" "35" "False" "" "1027" "R-HSA-8849474" "LeafAnnotation" "PTK6 Activates STAT3" "ReactomePathway" "1" "1" "4" "25" "False" "" "1028" "R-HSA-9705462" "LeafAnnotation" "Inactivation of CSF3 (G-CSF) signaling" "ReactomePathway" "11" "16" "25" "64" "False" "" "1029" "R-HSA-1839117" "LeafAnnotation" "Signaling by cytosolic FGFR1 fusion mutants" "ReactomePathway" "7" "9" "16" "56" "False" "" "1030" "R-HSA-9701898" "LeafAnnotation" "STAT3 nuclear events downstream of ALK signaling" "ReactomePathway" "5" "6" "10" "60" "False" "" "1031" "R-HSA-452723" "IntermediateAnnotation" "Transcriptional regulation of pluripotent stem cells" "ReactomePathway" "3" "4" "16" "25" "False" "" "1032" "R-HSA-111453" "LeafAnnotation" "BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members" "ReactomePathway" "5" "5" "9" "56" "False" "" "1033" "R-HSA-2892247" "LeafAnnotation" "POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation" "ReactomePathway" "3" "3" "12" "25" "False" "" "1034" "R-HSA-8984722" "LeafAnnotation" "Interleukin-35 Signalling" "ReactomePathway" "7" "7" "12" "58" "False" "" "1035" "R-HSA-9020933" "LeafAnnotation" "Interleukin-23 signaling" "ReactomePathway" "3" "3" "9" "33" "False" "" "1036" "R-HSA-9020956" "LeafAnnotation" "Interleukin-27 signaling" "ReactomePathway" "6" "6" "11" "55" "False" "" "1037" "R-HSA-198745" "LeafAnnotation" "Signalling to STAT3" "ReactomePathway" "1" "1" "3" "33" "False" "" "1038" "R-HSA-9725371" "LeafAnnotation" "Nuclear events stimulated by ALK signaling in cancer" "ReactomePathway" "13" "13" "18" "72" "False" "" "1039" "R-HSA-8875791" "LeafAnnotation" "MET activates STAT3" "ReactomePathway" "2" "2" "3" "67" "False" "" "1040" "R-HSA-8983432" "LeafAnnotation" "Interleukin-15 signaling" "ReactomePathway" "4" "4" "14" "29" "False" "" "1041" "R-HSA-8985947" "LeafAnnotation" "Interleukin-9 signaling" "ReactomePathway" "3" "3" "9" "33" "False" "" "1042" "R-HSA-9020958" "LeafAnnotation" "Interleukin-21 signaling" "ReactomePathway" "3" "3" "10" "30" "False" "" "1043" "R-HSA-6787639" "LeafAnnotation" "GDP-fucose biosynthesis" "ReactomePathway" "3" "3" "6" "50" "False" "" "1044" "R-HSA-727802" "LeafAnnotation" "Transport of nucleotide sugars" "ReactomePathway" "4" "4" "9" "44" "False" "" "1045" "R-HSA-5619078" "LeafAnnotation" "Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" "ReactomePathway" "1" "1" "1" "100" "False" "" "1046" "R-HSA-3899300" "LeafAnnotation" "SUMOylation of transcription cofactors" "ReactomePathway" "20" "21" "42" "50" "False" "" "1047" "R-HSA-6803529" "LeafAnnotation" "FGFR2 alternative splicing" "ReactomePathway" "17" "18" "25" "72" "False" "" "1048" "R-HSA-8851708" "LeafAnnotation" "Signaling by FGFR2 IIIa TM" "ReactomePathway" "12" "13" "19" "68" "False" "" "1049" "R-HSA-70221" "LeafAnnotation" "Glycogen breakdown (glycogenolysis)" "ReactomePathway" "9" "9" "13" "69" "False" "" "1050" "R-HSA-5625970" "LeafAnnotation" "RHO GTPases activate KTN1" "ReactomePathway" "9" "11" "11" "100" "False" "" "1051" "R-HSA-75876" "LeafAnnotation" "Synthesis of very long-chain fatty acyl-CoAs" "ReactomePathway" "9" "10" "24" "42" "False" "" "1052" "WP5269" "LeafAnnotation" "Genetic causes of porto-sinusoidal vascular disease" "WikiPathway" "15" "16" "37" "43" "False" "" "1053" "R-HSA-8964539" "LeafAnnotation" "Glutamate and glutamine metabolism" "ReactomePathway" "8" "9" "13" "69" "False" "" "1054" "WP1541" "LeafAnnotation" "Energy metabolism" "WikiPathway" "20" "23" "47" "49" "False" "" "1055" "WP1545" "LeafAnnotation" "miRNAs involved in DNA damage response" "WikiPathway" "5" "7" "15" "47" "False" "" "1056" "WP1589" "LeafAnnotation" "Folate-alcohol and cancer pathway hypotheses" "WikiPathway" "5" "7" "9" "78" "False" "" "1057" "WP2035" "LeafAnnotation" "Follicle stimulating hormone (FSH) signaling pathway" "WikiPathway" "13" "16" "27" "59" "False" "" "1058" "WP2516" "LeafAnnotation" "ATM signaling pathway" "WikiPathway" "6" "6" "19" "32" "False" "" "1059" "WP34" "LeafAnnotation" "Ovarian infertility" "WikiPathway" "12" "14" "36" "39" "False" "" "1060" "WP3584" "LeafAnnotation" "MECP2 and associated Rett syndrome" "WikiPathway" "30" "31" "72" "43" "False" "" "1061" "WP3599" "LeafAnnotation" "Transcription factor regulation in adipogenesis" "WikiPathway" "6" "7" "22" "32" "False" "" "1062" "WP3676" "LeafAnnotation" "BDNF-TrkB signaling" "WikiPathway" "14" "16" "32" "50" "False" "" "1063" "WP3853" "LeafAnnotation" "ERK pathway in Huntington's disease" "WikiPathway" "6" "7" "15" "47" "False" "" "1064" "WP391" "LeafAnnotation" "Mitochondrial gene expression" "WikiPathway" "8" "8" "19" "42" "False" "" "1065" "WP400" "LeafAnnotation" "p38 MAPK signaling pathway" "WikiPathway" "17" "18" "34" "53" "False" "" "1066" "WP4008" "LeafAnnotation" "NO/cGMP/PKG mediated neuroprotection" "WikiPathway" "11" "14" "44" "32" "False" "" "1067" "WP4149" "LeafAnnotation" "White fat cell differentiation" "WikiPathway" "7" "7" "32" "22" "False" "" "1068" "WP4222" "LeafAnnotation" "Phosphodiesterases in neuronal function" "WikiPathway" "9" "11" "54" "20" "False" "" "1069" "WP45" "LeafAnnotation" "G1 to S cell cycle control" "WikiPathway" "26" "30" "65" "46" "False" "" "1070" "WP4970" "LeafAnnotation" "Galanin receptor pathway" "WikiPathway" "6" "6" "21" "29" "False" "" "1071" "WP712" "LeafAnnotation" "Estrogen signaling pathway" "WikiPathway" "12" "15" "26" "58" "False" "" "1072" "WP734" "LeafAnnotation" "Serotonin receptor 4/6/7 and NR3C signaling" "WikiPathway" "8" "10" "21" "48" "False" "" "1073" "R-HSA-9022702" "LeafAnnotation" "MECP2 regulates transcription of neuronal ligands" "ReactomePathway" "3" "3" "7" "43" "False" "" "1074" "R-HSA-375165" "IntermediateAnnotation" "NCAM signaling for neurite out-growth" "ReactomePathway" "10" "13" "18" "72" "False" "" "1075" "R-HSA-199920" "LeafAnnotation" "CREB phosphorylation" "ReactomePathway" "3" "5" "7" "71" "False" "" "1076" "R-HSA-881907" "IntermediateAnnotation" "Gastrin-CREB signalling pathway via PKC and MAPK" "ReactomePathway" "4" "6" "9" "67" "False" "" "1077" "R-HSA-2197563" "LeafAnnotation" "NOTCH2 intracellular domain regulates transcription" "ReactomePathway" "3" "3" "12" "25" "False" "" "1078" "R-HSA-9022699" "LeafAnnotation" "MECP2 regulates neuronal receptors and channels" "ReactomePathway" "6" "6" "15" "40" "False" "" "1079" "R-HSA-111932" "LeafAnnotation" "CaMK IV-mediated phosphorylation of CREB" "ReactomePathway" "4" "6" "9" "67" "False" "" "1080" "R-HSA-442729" "LeafAnnotation" "CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde" "ReactomePathway" "3" "4" "7" "57" "False" "" "1081" "R-HSA-442742" "IntermediateAnnotation" "CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling" "ReactomePathway" "2" "4" "5" "80" "False" "" "1082" "R-HSA-9022707" "LeafAnnotation" "MECP2 regulates transcription factors" "ReactomePathway" "2" "2" "4" "50" "False" "" "1083" "R-HSA-3214841" "LeafAnnotation" "PKMTs methylate histone lysines" "ReactomePathway" "20" "21" "47" "45" "False" "" "1084" "WP4316" "LeafAnnotation" "miRNA degrading enzymes" "WikiPathway" "2" "2" "2" "100" "False" "" "1085" "R-HSA-450513" "LeafAnnotation" "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" "ReactomePathway" "13" "13" "17" "76" "False" "" "1086" "R-HSA-450385" "LeafAnnotation" "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" "ReactomePathway" "13" "13" "17" "76" "False" "" "1087" "WP4947" "LeafAnnotation" "Nitric oxide metabolism in cystic fibrosis" "WikiPathway" "5" "6" "13" "46" "False" "" "1088" "R-HSA-6804114" "LeafAnnotation" "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest" "ReactomePathway" "7" "7" "17" "41" "False" "" "1089" "WP4535" "LeafAnnotation" "Envelope proteins and their potential roles in EDMD physiopathology" "WikiPathway" "28" "30" "47" "64" "False" "" "1090" "R-HSA-170660" "LeafAnnotation" "Adenylate cyclase activating pathway" "ReactomePathway" "2" "4" "10" "40" "False" "" "1091" "WP2526" "LeafAnnotation" "PDGF pathway" "WikiPathway" "8" "8" "11" "73" "False" "" "1092" "WP3640" "LeafAnnotation" "Imatinib and chronic myeloid leukemia" "WikiPathway" "6" "8" "20" "40" "False" "" "1093" "WP4823" "LeafAnnotation" "Genes controlling nephrogenesis" "WikiPathway" "13" "15" "44" "34" "False" "" "1094" "WP5236" "LeafAnnotation" "Markers of kidney cell lineage" "WikiPathway" "16" "18" "57" "32" "False" "" "1095" "R-HSA-186797" "IntermediateAnnotation" "Signaling by PDGF" "ReactomePathway" "19" "21" "31" "68" "False" "" "1096" "WP3302" "LeafAnnotation" "eIF5A regulation in response to inhibition of the nuclear export system" "WikiPathway" "4" "4" "4" "100" "False" "" "1097" "R-HSA-428359" "LeafAnnotation" "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" "ReactomePathway" "3" "3" "3" "100" "False" "" "1098" "R-HSA-2172127" "IntermediateAnnotation" "DAP12 interactions" "ReactomePathway" "5" "5" "21" "24" "False" "" "1099" "R-HSA-6785470" "LeafAnnotation" "tRNA processing in the mitochondrion" "ReactomePathway" "5" "5" "5" "100" "False" "" "1100" "WP3624" "LeafAnnotation" "Lung fibrosis" "WikiPathway" "16" "17" "61" "28" "False" "" "1101" "WP3874" "LeafAnnotation" "Canonical and non-canonical TGF-B signaling" "WikiPathway" "9" "10" "16" "62" "False" "" "1102" "WP4830" "LeafAnnotation" "GDNF/RET signaling axis" "WikiPathway" "4" "5" "23" "22" "False" "" "1103" "WP268" "LeafAnnotation" "Notch signaling" "WikiPathway" "19" "22" "46" "48" "False" "" "1104" "WP3664" "LeafAnnotation" "Regulation of Wnt / B-catenin signaling by small molecule compounds" "WikiPathway" "7" "7" "16" "44" "False" "" "1105" "WP4150" "LeafAnnotation" "Wnt signaling in kidney disease" "WikiPathway" "11" "12" "36" "33" "False" "" "1106" "WP4241" "LeafAnnotation" "Type 2 papillary renal cell carcinoma" "WikiPathway" "12" "12" "33" "36" "False" "" "1107" "WP4258" "LeafAnnotation" "lncRNA in canonical Wnt signaling and colorectal cancer" "WikiPathway" "30" "36" "91" "40" "False" "" "1108" "WP428" "LeafAnnotation" "Wnt signaling" "WikiPathway" "41" "52" "113" "46" "False" "" "1109" "WP4336" "LeafAnnotation" "ncRNAs involved in Wnt signaling in hepatocellular carcinoma" "WikiPathway" "27" "33" "84" "39" "False" "" "1110" "WP710" "LeafAnnotation" "DNA damage response (only ATM dependent)" "WikiPathway" "41" "46" "102" "45" "False" "" "1111" "R-HSA-201681" "IntermediateAnnotation" "TCF dependent signaling in response to WNT" "ReactomePathway" "8" "12" "35" "34" "False" "" "1112" "R-HSA-201688" "LeafAnnotation" "WNT mediated activation of DVL" "ReactomePathway" "5" "7" "8" "88" "False" "" "1113" "R-HSA-4086400" "IntermediateAnnotation" "PCP/CE pathway" "ReactomePathway" "11" "13" "21" "62" "False" "" "1114" "R-HSA-5368598" "LeafAnnotation" "Negative regulation of TCF-dependent signaling by DVL-interacting proteins" "ReactomePathway" "1" "2" "5" "40" "False" "" "1115" "R-HSA-9673324" "LeafAnnotation" "WNT5:FZD7-mediated leishmania damping" "ReactomePathway" "5" "6" "12" "50" "False" "" "1116" "R-HSA-2028269" "LeafAnnotation" "Signaling by Hippo" "ReactomePathway" "14" "15" "19" "79" "False" "" "1117" "R-HSA-5099900" "LeafAnnotation" "WNT5A-dependent internalization of FZD4" "ReactomePathway" "11" "13" "15" "87" "False" "" "1118" "WP3529" "LeafAnnotation" "Zinc homeostasis" "WikiPathway" "12" "16" "35" "46" "False" "" "1119" "WP408" "LeafAnnotation" "Oxidative stress response" "WikiPathway" "17" "18" "33" "55" "False" "" "1120" "R-HSA-5661231" "LeafAnnotation" "Metallothioneins bind metals" "ReactomePathway" "1" "5" "11" "45" "False" "" "1121" "WP2916" "LeafAnnotation" "Interactome of polycomb repressive complex 2 (PRC2)" "WikiPathway" "7" "7" "16" "44" "False" "" "1122" "WP5211" "LeafAnnotation" "Glucose metabolism in triple-negative breast cancer cells" "WikiPathway" "8" "8" "8" "100" "False" "" "1123" "R-HSA-9013424" "LeafAnnotation" "RHOV GTPase cycle" "ReactomePathway" "25" "27" "37" "73" "False" "" "1124" "R-HSA-8854214" "LeafAnnotation" "TBC/RABGAPs" "ReactomePathway" "30" "32" "42" "76" "False" "" "1125" "WP2435" "LeafAnnotation" "Quercetin and Nf-kB / AP-1 induced apoptosis" "WikiPathway" "5" "6" "16" "38" "False" "" "1126" "WP3612" "LeafAnnotation" "Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling" "WikiPathway" "11" "11" "23" "48" "False" "" "1127" "WP3680" "LeafAnnotation" "Physico-chemical features and toxicity-associated pathways" "WikiPathway" "36" "42" "64" "66" "False" "" "1128" "WP3927" "LeafAnnotation" "BMP signaling in eyelid development" "WikiPathway" "5" "6" "20" "30" "False" "" "1129" "WP422" "LeafAnnotation" "MAPK cascade" "WikiPathway" "19" "22" "33" "67" "False" "" "1130" "WP4341" "LeafAnnotation" "Non-genomic actions of 1,25 dihydroxyvitamin D3" "WikiPathway" "26" "31" "68" "46" "False" "" "1131" "WP4877" "LeafAnnotation" "Host-pathogen interaction of human coronaviruses - MAPK signaling" "WikiPathway" "11" "17" "36" "47" "False" "" "1132" "WP4880" "LeafAnnotation" "Host-pathogen interaction of human coronaviruses - interferon induction" "WikiPathway" "17" "18" "33" "55" "False" "" "1133" "WP4919" "LeafAnnotation" "Neuroinflammation" "WikiPathway" "5" "6" "13" "46" "False" "" "1134" "WP4928" "LeafAnnotation" "MAPK pathway in congenital thyroid cancer" "WikiPathway" "6" "8" "14" "57" "False" "" "1135" "WP5300" "LeafAnnotation" "TROP2 regulatory signaling" "WikiPathway" "31" "34" "50" "68" "False" "" "1136" "R-HSA-2871796" "LeafAnnotation" "FCERI mediated MAPK activation" "ReactomePathway" "13" "18" "85" "21" "False" "" "1137" "R-HSA-450341" "LeafAnnotation" "Activation of the AP-1 family of transcription factors" "ReactomePathway" "4" "4" "10" "40" "False" "" "1138" "R-HSA-446193" "IntermediateAnnotation" "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" "ReactomePathway" "9" "9" "15" "60" "False" "" "1139" "R-HSA-4549380" "LeafAnnotation" "Defective ALG1 causes CDG-1k" "ReactomePathway" "1" "1" "1" "100" "False" "" "1140" "R-HSA-5655302" "IntermediateAnnotation" "Signaling by FGFR1 in disease" "ReactomePathway" "11" "13" "27" "48" "False" "" "1141" "R-HSA-9703465" "LeafAnnotation" "Signaling by FLT3 fusion proteins" "ReactomePathway" "7" "8" "17" "47" "False" "" "1142" "WP1981" "LeafAnnotation" "Thyroxine (thyroid hormone) production" "WikiPathway" "9" "10" "20" "50" "False" "" "1143" "WP2011" "LeafAnnotation" "SREBF and miR33 in cholesterol and lipid homeostasis" "WikiPathway" "9" "9" "16" "56" "False" "" "1144" "WP3595" "LeafAnnotation" "mir-124 predicted interactions with cell cycle and differentiation" "WikiPathway" "2" "2" "5" "40" "False" "" "1145" "WP3934" "LeafAnnotation" "Leptin and adiponectin" "WikiPathway" "5" "5" "10" "50" "False" "" "1146" "WP5046" "LeafAnnotation" "NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence" "WikiPathway" "14" "14" "22" "64" "False" "" "1147" "R-HSA-6804756" "LeafAnnotation" "Regulation of TP53 Activity through Phosphorylation" "ReactomePathway" "25" "31" "91" "34" "False" "" "1148" "R-HSA-111465" "IntermediateAnnotation" "Apoptotic cleavage of cellular proteins" "ReactomePathway" "9" "11" "18" "61" "False" "" "1149" "R-HSA-5694530" "LeafAnnotation" "Cargo concentration in the ER" "ReactomePathway" "23" "23" "33" "70" "False" "" "1150" "R-HSA-948021" "IntermediateAnnotation" "Transport to the Golgi and subsequent modification" "ReactomePathway" "2" "2" "2" "100" "False" "" "1151" "R-HSA-427975" "LeafAnnotation" "Proton/oligopeptide cotransporters" "ReactomePathway" "2" "2" "4" "50" "False" "" "1152" "R-HSA-390450" "LeafAnnotation" "Folding of actin by CCT/TriC" "ReactomePathway" "10" "10" "10" "100" "False" "" "1153" "R-HSA-141430" "LeafAnnotation" "Inactivation of APC/C via direct inhibition of the APC/C complex" "ReactomePathway" "9" "9" "20" "45" "False" "" "1154" "R-HSA-174048" "LeafAnnotation" "APC/C:Cdc20 mediated degradation of Cyclin B" "ReactomePathway" "9" "12" "23" "52" "False" "" "1155" "R-HSA-176407" "LeafAnnotation" "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" "ReactomePathway" "7" "7" "19" "37" "False" "" "1156" "R-HSA-176408" "IntermediateAnnotation" "Regulation of APC/C activators between G1/S and early anaphase" "ReactomePathway" "8" "9" "24" "38" "False" "" "1157" "R-HSA-176409" "IntermediateAnnotation" "APC/C:Cdc20 mediated degradation of mitotic proteins" "ReactomePathway" "9" "9" "20" "45" "False" "" "1158" "R-HSA-176412" "LeafAnnotation" "Phosphorylation of the APC/C" "ReactomePathway" "8" "8" "19" "42" "False" "" "1159" "R-HSA-179409" "LeafAnnotation" "APC-Cdc20 mediated degradation of Nek2A" "ReactomePathway" "10" "13" "25" "52" "False" "" "1160" "R-HSA-8853884" "LeafAnnotation" "Transcriptional Regulation by VENTX" "ReactomePathway" "16" "18" "38" "47" "False" "" "1161" "R-HSA-9687136" "LeafAnnotation" "Aberrant regulation of mitotic exit in cancer due to RB1 defects" "ReactomePathway" "8" "8" "19" "42" "False" "" "1162" "R-HSA-4085001" "LeafAnnotation" "Sialic acid metabolism" "ReactomePathway" "9" "9" "33" "27" "False" "" "1163" "R-HSA-4341670" "LeafAnnotation" "Defective NEU1 causes sialidosis" "ReactomePathway" "3" "3" "3" "100" "False" "" "1164" "WP5202" "LeafAnnotation" "Alstrom syndrome" "WikiPathway" "14" "15" "33" "45" "False" "" "1165" "R-HSA-2871809" "LeafAnnotation" "FCERI mediated Ca+2 mobilization" "ReactomePathway" "12" "17" "84" "20" "False" "" "1166" "R-HSA-5607763" "LeafAnnotation" "CLEC7A (Dectin-1) induces NFAT activation" "ReactomePathway" "7" "7" "10" "70" "False" "" "1167" "R-HSA-2025928" "LeafAnnotation" "Calcineurin activates NFAT" "ReactomePathway" "5" "5" "8" "62" "False" "" "1168" "WP3872" "LeafAnnotation" "Regulation of apoptosis by parathyroid hormone-related protein" "WikiPathway" "10" "10" "21" "48" "False" "" "1169" "R-HSA-5696394" "LeafAnnotation" "DNA Damage Recognition in GG-NER" "ReactomePathway" "22" "25" "38" "66" "False" "" "1170" "WP4922" "LeafAnnotation" "Mitochondrial complex IV assembly" "WikiPathway" "20" "20" "34" "59" "False" "" "1171" "R-HSA-3295583" "LeafAnnotation" "TRP channels" "ReactomePathway" "7" "7" "27" "26" "False" "" "1172" "WP4723" "LeafAnnotation" "Omega-3 / omega-6 fatty acid synthesis" "WikiPathway" "7" "8" "14" "57" "False" "" "1173" "R-HSA-163765" "LeafAnnotation" "ChREBP activates metabolic gene expression" "ReactomePathway" "5" "6" "7" "86" "False" "" "1174" "R-HSA-901032" "LeafAnnotation" "ER Quality Control Compartment (ERQC)" "ReactomePathway" "11" "14" "21" "67" "False" "" "1175" "R-HSA-532668" "IntermediateAnnotation" "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" "ReactomePathway" "11" "14" "16" "88" "False" "" "1176" "R-HSA-418889" "LeafAnnotation" "Caspase activation via Dependence Receptors in the absence of ligand" "ReactomePathway" "4" "4" "10" "40" "False" "" "1177" "R-HSA-1296072" "LeafAnnotation" "Voltage gated Potassium channels" "ReactomePathway" "3" "3" "43" "7" "False" "" "1178" "WP1425" "LeafAnnotation" "Bone morphogenic protein signaling and regulation" "WikiPathway" "1" "2" "12" "17" "False" "" "1179" "WP4787" "LeafAnnotation" "Osteoblast differentiation and related diseases" "WikiPathway" "31" "43" "118" "36" "False" "" "1180" "R-HSA-201451" "LeafAnnotation" "Signaling by BMP" "ReactomePathway" "5" "8" "28" "29" "False" "" "1181" "R-HSA-381753" "IntermediateAnnotation" "Olfactory Signaling Pathway" "ReactomePathway" "2" "3" "73" "4" "False" "" "1182" "R-HSA-1614517" "LeafAnnotation" "Sulfide oxidation to sulfate" "ReactomePathway" "5" "5" "6" "83" "False" "" "1183" "WP5027" "LeafAnnotation" "nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell" "WikiPathway" "16" "16" "16" "100" "False" "" "1184" "R-HSA-72649" "LeafAnnotation" "Translation initiation complex formation" "ReactomePathway" "57" "58" "58" "100" "False" "" "1185" "R-HSA-72695" "LeafAnnotation" "Formation of the ternary complex, and subsequently, the 43S complex" "ReactomePathway" "50" "51" "51" "100" "False" "" "1186" "R-HSA-72702" "LeafAnnotation" "Ribosomal scanning and start codon recognition" "ReactomePathway" "57" "58" "58" "100" "False" "" "1187" "R-HSA-196783" "LeafAnnotation" "Coenzyme A biosynthesis" "ReactomePathway" "4" "4" "8" "50" "False" "" "1188" "R-HSA-203615" "LeafAnnotation" "eNOS activation" "ReactomePathway" "7" "7" "10" "70" "False" "" "1189" "R-HSA-1474151" "LeafAnnotation" "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" "ReactomePathway" "3" "3" "9" "33" "False" "" "1190" "R-HSA-1442490" "LeafAnnotation" "Collagen degradation" "ReactomePathway" "27" "29" "63" "46" "False" "" "1191" "R-HSA-1650814" "IntermediateAnnotation" "Collagen biosynthesis and modifying enzymes" "ReactomePathway" "34" "35" "66" "53" "False" "" "1192" "R-HSA-419037" "LeafAnnotation" "NCAM1 interactions" "ReactomePathway" "16" "17" "42" "40" "False" "" "1193" "R-HSA-8948216" "LeafAnnotation" "Collagen chain trimerization" "ReactomePathway" "17" "18" "43" "42" "False" "" "1194" "R-HSA-5601884" "LeafAnnotation" "PIWI-interacting RNA (piRNA) biogenesis" "ReactomePathway" "10" "11" "29" "38" "False" "" "1195" "WP1742" "LeafAnnotation" "TP53 network" "WikiPathway" "7" "7" "21" "33" "False" "" "1196" "R-HSA-5693565" "LeafAnnotation" "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" "ReactomePathway" "22" "39" "60" "65" "False" "" "1197" "R-HSA-4655427" "LeafAnnotation" "SUMOylation of DNA methylation proteins" "ReactomePathway" "5" "5" "15" "33" "False" "" "1198" "R-HSA-4090294" "LeafAnnotation" "SUMOylation of intracellular receptors" "ReactomePathway" "4" "4" "24" "17" "False" "" "1199" "R-HSA-3232118" "LeafAnnotation" "SUMOylation of transcription factors" "ReactomePathway" "6" "6" "18" "33" "False" "" "1200" "R-HSA-8866904" "LeafAnnotation" "Negative regulation of activity of TFAP2 (AP-2) family transcription factors" "ReactomePathway" "1" "1" "10" "10" "False" "" "1201" "R-HSA-9694631" "LeafAnnotation" "Maturation of nucleoprotein" "ReactomePathway" "11" "11" "15" "73" "False" "" "1202" "R-HSA-4755510" "LeafAnnotation" "SUMOylation of immune response proteins" "ReactomePathway" "5" "5" "11" "45" "False" "" "1203" "R-HSA-9793242" "IntermediateAnnotation" "SUMOylation of nuclear envelope proteins" "ReactomePathway" "2" "2" "3" "67" "False" "" "1204" "R-HSA-9683610" "LeafAnnotation" "Maturation of nucleoprotein" "ReactomePathway" "7" "7" "11" "64" "False" "" "1205" "R-HSA-3065676" "LeafAnnotation" "SUMO is conjugated to E1 (UBA2:SAE1)" "ReactomePathway" "5" "5" "5" "100" "False" "" "1206" "R-HSA-3065678" "LeafAnnotation" "SUMO is transferred from E1 to E2 (UBE2I, UBC9)" "ReactomePathway" "5" "5" "7" "71" "False" "" "1207" "R-HSA-3065679" "LeafAnnotation" "SUMO is proteolytically processed" "ReactomePathway" "3" "3" "6" "50" "False" "" "1208" "WP3967" "LeafAnnotation" "miR-509-3p alteration of YAP1/ECM axis" "WikiPathway" "8" "9" "16" "56" "False" "" "1209" "WP4533" "LeafAnnotation" "Transcription co-factors SKI and SKIL protein partners" "WikiPathway" "7" "8" "18" "44" "False" "" "1210" "WP4537" "LeafAnnotation" "Hippo-YAP signaling" "WikiPathway" "8" "9" "23" "39" "False" "" "1211" "WP4542" "LeafAnnotation" "Leukocyte-intrinsic Hippo pathway functions" "WikiPathway" "10" "11" "33" "33" "False" "" "1212" "R-HSA-2032785" "LeafAnnotation" "YAP1- and WWTR1 (TAZ)-stimulated gene expression" "ReactomePathway" "4" "4" "14" "29" "False" "" "1213" "R-HSA-8951671" "LeafAnnotation" "RUNX3 regulates YAP1-mediated transcription" "ReactomePathway" "4" "4" "8" "50" "False" "" "1214" "WP2197" "LeafAnnotation" "Endothelin pathways" "WikiPathway" "12" "14" "33" "42" "False" "" "1215" "WP3298" "LeafAnnotation" "Melatonin metabolism and effects" "WikiPathway" "9" "10" "32" "31" "False" "" "1216" "R-HSA-111367" "LeafAnnotation" "SLBP independent Processing of Histone Pre-mRNAs" "ReactomePathway" "6" "7" "10" "70" "False" "" "1217" "R-HSA-77588" "LeafAnnotation" "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" "ReactomePathway" "6" "7" "11" "64" "False" "" "1218" "R-HSA-9754560" "LeafAnnotation" "SARS-CoV-2 modulates autophagy" "ReactomePathway" "8" "9" "10" "90" "False" "" "1219" "R-HSA-1971475" "LeafAnnotation" "A tetrasaccharide linker sequence is required for GAG synthesis" "ReactomePathway" "16" "16" "26" "62" "False" "" "1220" "R-HSA-2022928" "LeafAnnotation" "HS-GAG biosynthesis" "ReactomePathway" "14" "14" "31" "45" "False" "" "1221" "R-HSA-2024096" "LeafAnnotation" "HS-GAG degradation" "ReactomePathway" "14" "14" "22" "64" "False" "" "1222" "R-HSA-3560783" "LeafAnnotation" "Defective B4GALT7 causes EDS, progeroid type" "ReactomePathway" "13" "13" "20" "65" "False" "" "1223" "R-HSA-3560801" "LeafAnnotation" "Defective B3GAT3 causes JDSSDHD" "ReactomePathway" "13" "13" "20" "65" "False" "" "1224" "R-HSA-3656237" "LeafAnnotation" "Defective EXT2 causes exostoses 2" "ReactomePathway" "10" "10" "14" "71" "False" "" "1225" "R-HSA-3656253" "LeafAnnotation" "Defective EXT1 causes exostoses 1, TRPS2 and CHDS" "ReactomePathway" "10" "10" "14" "71" "False" "" "1226" "R-HSA-4420332" "LeafAnnotation" "Defective B3GALT6 causes EDSP2 and SEMDJL1" "ReactomePathway" "13" "13" "20" "65" "False" "" "1227" "R-HSA-9694614" "LeafAnnotation" "Attachment and Entry" "ReactomePathway" "13" "13" "19" "68" "False" "" "1228" "R-HSA-975634" "LeafAnnotation" "Retinoid metabolism and transport" "ReactomePathway" "17" "19" "43" "44" "False" "" "1229" "R-HSA-8851680" "LeafAnnotation" "Butyrophilin (BTN) family interactions" "ReactomePathway" "3" "6" "12" "50" "False" "" "1230" "WP5176" "LeafAnnotation" "Disorders of bile acid synthesis and biliary transport" "WikiPathway" "5" "5" "15" "33" "False" "" "1231" "R-HSA-77111" "LeafAnnotation" "Synthesis of Ketone Bodies" "ReactomePathway" "4" "5" "8" "62" "False" "" "1232" "R-HSA-1660661" "LeafAnnotation" "Sphingolipid de novo biosynthesis" "ReactomePathway" "16" "22" "43" "51" "False" "" "1233" "WP3865" "LeafAnnotation" "Novel intracellular components of RIG-I-like receptor pathway" "WikiPathway" "24" "26" "60" "43" "False" "" "1234" "R-HSA-5619072" "LeafAnnotation" "Defective SLC35A2 causes congenital disorder of glycosylation 2M (CDG2M)" "ReactomePathway" "1" "1" "1" "100" "False" "" "1235" "R-HSA-6783310" "IntermediateAnnotation" "Fanconi Anemia Pathway" "ReactomePathway" "5" "8" "38" "21" "False" "" "1236" "R-HSA-75105" "IntermediateAnnotation" "Fatty acyl-CoA biosynthesis" "ReactomePathway" "10" "10" "14" "71" "False" "" "1237" "R-HSA-428540" "LeafAnnotation" "Activation of RAC1" "ReactomePathway" "7" "8" "13" "62" "False" "" "1238" "R-HSA-9754678" "LeafAnnotation" "SARS-CoV-2 modulates host translation machinery" "ReactomePathway" "42" "44" "49" "90" "False" "" "1239" "R-HSA-9735869" "IntermediateAnnotation" "SARS-CoV-1 modulates host translation machinery" "ReactomePathway" "35" "36" "36" "100" "False" "" "1240" "R-HSA-2408508" "LeafAnnotation" "Metabolism of ingested SeMet, Sec, MeSec into H2Se" "ReactomePathway" "5" "5" "8" "62" "False" "" "1241" "R-HSA-399956" "LeafAnnotation" "CRMPs in Sema3A signaling" "ReactomePathway" "6" "8" "15" "53" "False" "" "1242" "WP2817" "LeafAnnotation" "Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)" "WikiPathway" "11" "13" "33" "39" "False" "" "1243" "R-HSA-8849472" "LeafAnnotation" "PTK6 Down-Regulation" "ReactomePathway" "1" "1" "3" "33" "False" "" "1244" "R-HSA-418990" "IntermediateAnnotation" "Adherens junctions interactions" "ReactomePathway" "13" "15" "31" "48" "False" "" "1245" "R-HSA-420597" "LeafAnnotation" "Nectin/Necl trans heterodimerization" "ReactomePathway" "4" "4" "7" "57" "False" "" "1246" "WP5194" "LeafAnnotation" "Synthesis of ceramides and 1-deoxyceramides" "WikiPathway" "6" "6" "21" "29" "False" "" "1247" "R-HSA-5693607" "LeafAnnotation" "Processing of DNA double-strand break ends" "ReactomePathway" "23" "41" "80" "51" "False" "" "1248" "R-HSA-69473" "IntermediateAnnotation" "G2/M DNA damage checkpoint" "ReactomePathway" "19" "33" "66" "50" "False" "" "1249" "WP2828" "LeafAnnotation" "Bladder cancer" "WikiPathway" "20" "24" "41" "59" "False" "" "1250" "WP2864" "LeafAnnotation" "Apoptosis-related network due to altered Notch3 in ovarian cancer" "WikiPathway" "31" "31" "53" "58" "False" "" "1251" "WP453" "LeafAnnotation" "Inflammatory response pathway" "WikiPathway" "12" "14" "31" "45" "False" "" "1252" "R-HSA-5083635" "LeafAnnotation" "Defective B3GALTL causes PpS" "ReactomePathway" "7" "8" "37" "22" "False" "" "1253" "R-HSA-5173214" "LeafAnnotation" "O-glycosylation of TSR domain-containing proteins" "ReactomePathway" "8" "9" "38" "24" "False" "" "1254" "WP1422" "LeafAnnotation" "Sphingolipid pathway" "WikiPathway" "14" "14" "28" "50" "False" "" "1255" "R-HSA-1251985" "LeafAnnotation" "Nuclear signaling by ERBB4" "ReactomePathway" "10" "12" "31" "39" "False" "" "1256" "R-HSA-5223345" "LeafAnnotation" "Miscellaneous transport and binding events" "ReactomePathway" "13" "14" "25" "56" "False" "" "1257" "R-HSA-913709" "IntermediateAnnotation" "O-linked glycosylation of mucins" "ReactomePathway" "13" "14" "57" "25" "False" "" "1258" "R-HSA-9683686" "LeafAnnotation" "Maturation of spike protein" "ReactomePathway" "5" "5" "5" "100" "False" "" "1259" "R-HSA-964739" "IntermediateAnnotation" "N-glycan trimming and elongation in the cis-Golgi" "ReactomePathway" "1" "1" "2" "50" "False" "" "1260" "R-HSA-168928" "IntermediateAnnotation" "DDX58/IFIH1-mediated induction of interferon-alpha/beta" "ReactomePathway" "13" "16" "23" "70" "False" "" "1261" "R-HSA-9692916" "IntermediateAnnotation" "SARS-CoV-1 activates/modulates innate immune responses" "ReactomePathway" "22" "25" "41" "61" "False" "" "1262" "R-HSA-70350" "LeafAnnotation" "Fructose catabolism" "ReactomePathway" "2" "3" "5" "60" "False" "" "1263" "WP1946" "LeafAnnotation" "Cori cycle" "WikiPathway" "11" "12" "16" "75" "False" "" "1264" "WP5283" "LeafAnnotation" "Chronic hyperglycemia impairment of neuron function" "WikiPathway" "10" "14" "42" "33" "False" "" "1265" "R-HSA-975578" "LeafAnnotation" "Reactions specific to the complex N-glycan synthesis pathway" "ReactomePathway" "5" "5" "10" "50" "False" "" "1266" "R-HSA-210455" "LeafAnnotation" "Astrocytic Glutamate-Glutamine Uptake And Metabolism" "ReactomePathway" "2" "2" "4" "50" "False" "" "1267" "R-HSA-8935690" "IntermediateAnnotation" "Digestion" "ReactomePathway" "1" "1" "5" "20" "False" "" "1268" "WP247" "LeafAnnotation" "Small ligand GPCRs" "WikiPathway" "4" "4" "19" "21" "False" "" "1269" "WP5121" "LeafAnnotation" "Sphingolipid metabolism in senescence" "WikiPathway" "11" "12" "19" "63" "False" "" "1270" "R-HSA-419408" "LeafAnnotation" "Lysosphingolipid and LPA receptors" "ReactomePathway" "4" "4" "13" "31" "False" "" "1271" "WP117" "LeafAnnotation" "GPCRs, other" "WikiPathway" "5" "6" "88" "7" "False" "" "1272" "R-HSA-1482839" "LeafAnnotation" "Acyl chain remodelling of PE" "ReactomePathway" "5" "5" "29" "17" "False" "" "1273" "WP2290" "LeafAnnotation" "RalA downstream regulated genes" "WikiPathway" "11" "12" "12" "100" "False" "" "1274" "WP2586" "LeafAnnotation" "Aryl hydrocarbon receptor pathway" "WikiPathway" "17" "21" "45" "47" "False" "" "1275" "WP2870" "LeafAnnotation" "Extracellular vesicle-mediated signaling in recipient cells" "WikiPathway" "14" "16" "30" "53" "False" "" "1276" "WP3844" "LeafAnnotation" "PI3K-AKT-mTOR signaling pathway and therapeutic opportunities" "WikiPathway" "15" "17" "30" "57" "False" "" "1277" "WP4301" "LeafAnnotation" "Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells" "WikiPathway" "16" "18" "18" "100" "False" "" "1278" "WP732" "LeafAnnotation" "Serotonin receptor 2 and ELK-SRF/GATA4 signaling" "WikiPathway" "9" "10" "18" "56" "False" "" "1279" "R-HSA-9648002" "LeafAnnotation" "RAS processing" "ReactomePathway" "12" "16" "23" "70" "False" "" "1280" "R-HSA-9753510" "LeafAnnotation" "Signaling by RAS GAP mutants" "ReactomePathway" "3" "3" "3" "100" "False" "" "1281" "R-HSA-9753512" "LeafAnnotation" "Signaling by RAS GTPase mutants" "ReactomePathway" "3" "3" "3" "100" "False" "" "1282" "R-HSA-8951936" "LeafAnnotation" "RUNX3 regulates p14-ARF" "ReactomePathway" "4" "4" "9" "44" "False" "" "1283" "WP3998" "LeafAnnotation" "Prader-Willi and Angelman syndrome" "WikiPathway" "6" "7" "37" "19" "False" "" "1284" "WP5055" "LeafAnnotation" "Burn wound healing" "WikiPathway" "11" "11" "30" "37" "False" "" "1285" "R-HSA-3000497" "LeafAnnotation" "Scavenging by Class H Receptors" "ReactomePathway" "2" "2" "4" "50" "False" "" "1286" "WP4725" "LeafAnnotation" "Sphingolipid metabolism overview" "WikiPathway" "12" "12" "23" "52" "False" "" "1287" "WP4726" "LeafAnnotation" "Sphingolipid metabolism: integrated pathway" "WikiPathway" "12" "12" "24" "50" "False" "" "1288" "R-HSA-3134975" "IntermediateAnnotation" "Regulation of innate immune responses to cytosolic DNA" "ReactomePathway" "8" "11" "14" "79" "False" "" "1289" "WP1433" "LeafAnnotation" "Nucleotide-binding oligomerization domain (NOD) pathway" "WikiPathway" "12" "13" "40" "32" "False" "" "1290" "R-HSA-2022854" "LeafAnnotation" "Keratan sulfate biosynthesis" "ReactomePathway" "6" "6" "28" "21" "False" "" "1291" "WP124" "LeafAnnotation" "Irinotecan pathway" "WikiPathway" "1" "1" "4" "25" "False" "" "1292" "R-HSA-8964038" "LeafAnnotation" "LDL clearance" "ReactomePathway" "15" "15" "19" "79" "False" "" "1293" "WP100" "LeafAnnotation" "Glutathione metabolism" "WikiPathway" "13" "13" "20" "65" "False" "" "1294" "WP2525" "LeafAnnotation" "Trans-sulfuration, one-carbon metabolism and related pathways" "WikiPathway" "33" "35" "66" "53" "False" "" "1295" "WP692" "LeafAnnotation" "Sulfation biotransformation reaction" "WikiPathway" "4" "4" "16" "25" "False" "" "1296" "WP4786" "LeafAnnotation" "Type I collagen synthesis in the context of osteogenesis imperfecta" "WikiPathway" "23" "23" "32" "72" "False" "" "1297" "WP455" "LeafAnnotation" "GPCRs, class A rhodopsin-like" "WikiPathway" "5" "5" "253" "2" "False" "" "1298" "R-HSA-391908" "LeafAnnotation" "Prostanoid ligand receptors" "ReactomePathway" "1" "1" "9" "11" "False" "" "1299" "R-HSA-196780" "LeafAnnotation" "Biotin transport and metabolism" "ReactomePathway" "6" "7" "11" "64" "False" "" "1300" "R-HSA-3371599" "LeafAnnotation" "Defective HLCS causes multiple carboxylase deficiency" "ReactomePathway" "6" "6" "7" "86" "False" "" "1301" "R-HSA-71032" "LeafAnnotation" "Propionyl-CoA catabolism" "ReactomePathway" "4" "4" "5" "80" "False" "" "1302" "R-HSA-9615017" "LeafAnnotation" "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" "ReactomePathway" "10" "11" "30" "37" "False" "" "1303" "R-HSA-5689877" "LeafAnnotation" "Josephin domain DUBs" "ReactomePathway" "5" "8" "12" "67" "False" "" "1304" "R-HSA-6782315" "IntermediateAnnotation" "tRNA modification in the nucleus and cytosol" "ReactomePathway" "11" "11" "36" "31" "False" "" "1305" "WP4238" "LeafAnnotation" "Flavan-3-ol metabolic pathway" "WikiPathway" "1" "1" "1" "100" "False" "" "1306" "WP4288" "LeafAnnotation" "MTHFR deficiency" "WikiPathway" "4" "4" "10" "40" "False" "" "1307" "WP550" "LeafAnnotation" "Biogenic amine synthesis" "WikiPathway" "3" "3" "15" "20" "False" "" "1308" "WP697" "LeafAnnotation" "Estrogen metabolism" "WikiPathway" "6" "6" "18" "33" "False" "" "1309" "WP704" "LeafAnnotation" "Methylation pathways" "WikiPathway" "5" "5" "9" "56" "False" "" "1310" "R-HSA-379397" "LeafAnnotation" "Enzymatic degradation of dopamine by COMT" "ReactomePathway" "2" "2" "3" "67" "False" "" "1311" "R-HSA-379398" "LeafAnnotation" "Enzymatic degradation of Dopamine by monoamine oxidase" "ReactomePathway" "2" "2" "2" "100" "False" "" "1312" "WP3945" "LeafAnnotation" "TYROBP causal network in microglia" "WikiPathway" "15" "16" "60" "27" "False" "" "1313" "WP3208" "LeafAnnotation" "Ectoderm differentiation" "WikiPathway" "17" "23" "57" "40" "False" "" "1314" "R-HSA-8956319" "IntermediateAnnotation" "Nucleotide catabolism" "ReactomePathway" "1" "1" "1" "100" "False" "" "1315" "R-HSA-112310" "IntermediateAnnotation" "Neurotransmitter release cycle" "ReactomePathway" "1" "1" "1" "100" "False" "" "1316" "R-HSA-1655829" "IntermediateAnnotation" "Regulation of cholesterol biosynthesis by SREBP (SREBF)" "ReactomePathway" "9" "9" "14" "64" "False" "" "1317" "R-HSA-2995383" "LeafAnnotation" "Initiation of Nuclear Envelope (NE) Reformation" "ReactomePathway" "14" "14" "16" "88" "False" "" "1318" "R-HSA-9636249" "LeafAnnotation" "Inhibition of nitric oxide production" "ReactomePathway" "2" "2" "3" "67" "False" "" "1319" "WP5178" "LeafAnnotation" "Disorders of fructose metabolism" "WikiPathway" "7" "8" "14" "57" "False" "" "1320" "WP698" "LeafAnnotation" "Glucuronidation" "WikiPathway" "7" "7" "25" "28" "False" "" "1321" "R-HSA-5619056" "LeafAnnotation" "Defective HK1 causes hexokinase deficiency (HK deficiency)" "ReactomePathway" "1" "1" "1" "100" "False" "" "1322" "R-HSA-5620922" "LeafAnnotation" "BBSome-mediated cargo-targeting to cilium" "ReactomePathway" "8" "8" "22" "36" "False" "" "1323" "R-HSA-83936" "LeafAnnotation" "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" "ReactomePathway" "7" "7" "12" "58" "False" "" "1324" "R-HSA-168277" "LeafAnnotation" "Influenza Virus Induced Apoptosis" "ReactomePathway" "1" "1" "2" "50" "False" "" "1325" "R-HSA-180897" "LeafAnnotation" "Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization" "ReactomePathway" "3" "3" "3" "100" "False" "" "1326" "R-HSA-68962" "LeafAnnotation" "Activation of the pre-replicative complex" "ReactomePathway" "14" "15" "33" "45" "False" "" "1327" "R-HSA-68952" "LeafAnnotation" "DNA replication initiation" "ReactomePathway" "3" "3" "8" "38" "False" "" "1328" "R-HSA-72731" "LeafAnnotation" "Recycling of eIF2:GDP" "ReactomePathway" "8" "8" "8" "100" "False" "" "1329" "R-HSA-373080" "IntermediateAnnotation" "Class B/2 (Secretin family receptors)" "ReactomePathway" "8" "9" "50" "18" "False" "" "1330" "WP1601" "LeafAnnotation" "Fluoropyrimidine activity" "WikiPathway" "13" "14" "33" "42" "False" "" "1331" "R-HSA-500753" "LeafAnnotation" "Pyrimidine biosynthesis" "ReactomePathway" "2" "2" "3" "67" "False" "" "1332" "R-HSA-9609523" "LeafAnnotation" "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" "ReactomePathway" "14" "14" "19" "74" "False" "" "1333" "R-HSA-9664873" "LeafAnnotation" "Pexophagy" "ReactomePathway" "4" "8" "11" "73" "False" "" "1334" "WP5285" "LeafAnnotation" "Immune infiltration in pancreatic cancer" "WikiPathway" "4" "4" "38" "11" "False" "" "1335" "WP2814" "LeafAnnotation" "Mammary gland development pathway - Puberty (Stage 2 of 4)" "WikiPathway" "5" "6" "13" "46" "False" "" "1336" "WP3859" "LeafAnnotation" "TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition" "WikiPathway" "7" "8" "14" "57" "False" "" "1337" "R-HSA-264870" "LeafAnnotation" "Caspase-mediated cleavage of cytoskeletal proteins" "ReactomePathway" "8" "8" "12" "67" "False" "" "1338" "WP3937" "LeafAnnotation" "Microglia pathogen phagocytosis pathway" "WikiPathway" "8" "12" "39" "31" "False" "" "1339" "R-HSA-9664565" "LeafAnnotation" "Signaling by ERBB2 KD Mutants" "ReactomePathway" "9" "10" "21" "48" "False" "" "1340" "R-HSA-9665686" "LeafAnnotation" "Signaling by ERBB2 TMD/JMD mutants" "ReactomePathway" "9" "9" "18" "50" "False" "" "1341" "R-HSA-1236382" "LeafAnnotation" "Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants" "ReactomePathway" "9" "13" "17" "76" "False" "" "1342" "R-HSA-5637810" "LeafAnnotation" "Constitutive Signaling by EGFRvIII" "ReactomePathway" "8" "9" "13" "69" "False" "" "1343" "R-HSA-9665348" "LeafAnnotation" "Signaling by ERBB2 ECD mutants" "ReactomePathway" "9" "10" "14" "71" "False" "" "1344" "R-HSA-9634285" "LeafAnnotation" "Constitutive Signaling by Overexpressed ERBB2" "ReactomePathway" "8" "8" "9" "89" "False" "" "1345" "R-HSA-912526" "LeafAnnotation" "Interleukin receptor SHC signaling" "ReactomePathway" "4" "6" "26" "23" "False" "" "1346" "R-HSA-1250196" "LeafAnnotation" "SHC1 events in ERBB2 signaling" "ReactomePathway" "8" "8" "18" "44" "False" "" "1347" "R-HSA-1250347" "LeafAnnotation" "SHC1 events in ERBB4 signaling" "ReactomePathway" "3" "3" "11" "27" "False" "" "1348" "R-HSA-180336" "LeafAnnotation" "SHC1 events in EGFR signaling" "ReactomePathway" "4" "4" "12" "33" "False" "" "1349" "R-HSA-9027284" "LeafAnnotation" "Erythropoietin activates RAS" "ReactomePathway" "6" "6" "12" "50" "False" "" "1350" "R-HSA-167044" "IntermediateAnnotation" "Signalling to RAS" "ReactomePathway" "3" "4" "8" "50" "False" "" "1351" "R-HSA-74751" "IntermediateAnnotation" "Insulin receptor signalling cascade" "ReactomePathway" "3" "3" "7" "43" "False" "" "1352" "R-HSA-74749" "LeafAnnotation" "Signal attenuation" "ReactomePathway" "4" "4" "9" "44" "False" "" "1353" "R-HSA-9020558" "LeafAnnotation" "Interleukin-2 signaling" "ReactomePathway" "2" "3" "12" "25" "False" "" "1354" "WP3617" "LeafAnnotation" "Photodynamic therapy-induced NF-kB survival signaling" "WikiPathway" "12" "14" "35" "40" "False" "" "1355" "R-HSA-194306" "LeafAnnotation" "Neurophilin interactions with VEGF and VEGFR" "ReactomePathway" "3" "4" "4" "100" "False" "" "1356" "WP262" "LeafAnnotation" "Ebstein-Barr virus LMP1 signaling" "WikiPathway" "13" "14" "23" "61" "False" "" "1357" "WP2876" "LeafAnnotation" "Pregnane X receptor pathway" "WikiPathway" "8" "9" "31" "29" "False" "" "1358" "R-HSA-192905" "LeafAnnotation" "vRNP Assembly" "ReactomePathway" "2" "2" "2" "100" "False" "" "1359" "R-HSA-5675482" "IntermediateAnnotation" "Regulation of necroptotic cell death" "ReactomePathway" "14" "17" "26" "65" "False" "" "1360" "R-HSA-1227986" "IntermediateAnnotation" "Signaling by ERBB2" "ReactomePathway" "7" "8" "16" "50" "False" "" "1361" "R-HSA-8863795" "IntermediateAnnotation" "Downregulation of ERBB2 signaling" "ReactomePathway" "9" "12" "22" "55" "False" "" "1362" "R-HSA-399954" "LeafAnnotation" "Sema3A PAK dependent Axon repulsion" "ReactomePathway" "8" "10" "15" "67" "False" "" "1363" "R-HSA-3371511" "LeafAnnotation" "HSF1 activation" "ReactomePathway" "11" "11" "12" "92" "False" "" "1364" "R-HSA-3371568" "LeafAnnotation" "Attenuation phase" "ReactomePathway" "11" "11" "13" "85" "False" "" "1365" "R-HSA-5336415" "LeafAnnotation" "Uptake and function of diphtheria toxin" "ReactomePathway" "5" "5" "6" "83" "False" "" "1366" "R-HSA-8939211" "IntermediateAnnotation" "ESR-mediated signaling" "ReactomePathway" "8" "8" "11" "73" "False" "" "1367" "R-HSA-3000484" "LeafAnnotation" "Scavenging by Class F Receptors" "ReactomePathway" "5" "5" "6" "83" "False" "" "1368" "R-HSA-9652282" "LeafAnnotation" "Drug-mediated inhibition of ERBB2 signaling" "ReactomePathway" "4" "4" "4" "100" "False" "" "1369" "R-HSA-9665233" "LeafAnnotation" "Resistance of ERBB2 KD mutants to trastuzumab" "ReactomePathway" "4" "4" "4" "100" "False" "" "1370" "R-HSA-9665244" "LeafAnnotation" "Resistance of ERBB2 KD mutants to sapitinib" "ReactomePathway" "4" "4" "4" "100" "False" "" "1371" "R-HSA-9665245" "LeafAnnotation" "Resistance of ERBB2 KD mutants to tesevatinib" "ReactomePathway" "4" "4" "4" "100" "False" "" "1372" "R-HSA-9665246" "LeafAnnotation" "Resistance of ERBB2 KD mutants to neratinib" "ReactomePathway" "4" "4" "4" "100" "False" "" "1373" "R-HSA-9665247" "LeafAnnotation" "Resistance of ERBB2 KD mutants to osimertinib" "ReactomePathway" "4" "4" "4" "100" "False" "" "1374" "R-HSA-9665249" "LeafAnnotation" "Resistance of ERBB2 KD mutants to afatinib" "ReactomePathway" "4" "4" "4" "100" "False" "" "1375" "R-HSA-9665250" "LeafAnnotation" "Resistance of ERBB2 KD mutants to AEE788" "ReactomePathway" "4" "4" "4" "100" "False" "" "1376" "R-HSA-9665251" "LeafAnnotation" "Resistance of ERBB2 KD mutants to lapatinib" "ReactomePathway" "4" "4" "4" "100" "False" "" "1377" "R-HSA-9665737" "LeafAnnotation" "Drug resistance in ERBB2 TMD/JMD mutants" "ReactomePathway" "4" "4" "4" "100" "False" "" "1378" "R-HSA-9749641" "LeafAnnotation" "Aspirin ADME" "ReactomePathway" "6" "6" "41" "15" "False" "" "1379" "R-HSA-9793528" "IntermediateAnnotation" "Ciprofloxacin ADME" "ReactomePathway" "1" "1" "5" "20" "False" "" "1380" "R-HSA-159418" "LeafAnnotation" "Recycling of bile acids and salts" "ReactomePathway" "3" "3" "18" "17" "False" "" "1381" "R-HSA-9757110" "IntermediateAnnotation" "Prednisone ADME" "ReactomePathway" "3" "3" "10" "30" "False" "" "1382" "R-HSA-189483" "LeafAnnotation" "Heme degradation" "ReactomePathway" "6" "6" "14" "43" "False" "" "1383" "R-HSA-8964058" "LeafAnnotation" "HDL remodeling" "ReactomePathway" "3" "3" "9" "33" "False" "" "1384" "R-HSA-189451" "LeafAnnotation" "Heme biosynthesis" "ReactomePathway" "8" "8" "13" "62" "False" "" "1385" "R-HSA-390247" "LeafAnnotation" "Beta-oxidation of very long chain fatty acids" "ReactomePathway" "6" "7" "8" "88" "False" "" "1386" "WP241" "LeafAnnotation" "One-carbon metabolism" "WikiPathway" "15" "17" "28" "61" "False" "" "1387" "R-HSA-8983711" "LeafAnnotation" "OAS antiviral response" "ReactomePathway" "4" "4" "9" "44" "False" "" "1388" "R-HSA-2029485" "LeafAnnotation" "Role of phospholipids in phagocytosis" "ReactomePathway" "12" "17" "84" "20" "False" "" "1389" "R-HSA-1483148" "LeafAnnotation" "Synthesis of PG" "ReactomePathway" "6" "6" "8" "75" "False" "" "1390" "R-HSA-1834941" "IntermediateAnnotation" "STING mediated induction of host immune responses" "ReactomePathway" "4" "4" "5" "80" "False" "" "1391" "WP1539" "LeafAnnotation" "Angiogenesis" "WikiPathway" "10" "12" "20" "60" "False" "" "1392" "R-HSA-195399" "LeafAnnotation" "VEGF binds to VEGFR leading to receptor dimerization" "ReactomePathway" "3" "4" "8" "50" "False" "" "1393" "WP53" "LeafAnnotation" "ID signaling pathway" "WikiPathway" "3" "4" "16" "25" "False" "" "1394" "R-HSA-6804116" "LeafAnnotation" "TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest" "ReactomePathway" "1" "3" "14" "21" "False" "" "1395" "R-HSA-176187" "LeafAnnotation" "Activation of ATR in response to replication stress" "ReactomePathway" "13" "14" "37" "38" "False" "" "1396" "R-HSA-68911" "LeafAnnotation" "G2 Phase" "ReactomePathway" "0" "1" "5" "20" "False" "" "1397" "R-HSA-9661069" "LeafAnnotation" "Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)" "ReactomePathway" "5" "8" "17" "47" "False" "" "1398" "R-HSA-1538133" "IntermediateAnnotation" "G0 and Early G1" "ReactomePathway" "3" "4" "18" "22" "False" "" "1399" "R-HSA-69200" "LeafAnnotation" "Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes" "ReactomePathway" "1" "2" "4" "50" "False" "" "1400" "R-HSA-69563" "IntermediateAnnotation" "p53-Dependent G1 DNA Damage Response" "ReactomePathway" "1" "2" "7" "29" "False" "" "1401" "R-HSA-8849470" "LeafAnnotation" "PTK6 Regulates Cell Cycle" "ReactomePathway" "2" "3" "6" "50" "False" "" "1402" "R-HSA-9726840" "LeafAnnotation" "SHOC2 M1731 mutant abolishes MRAS complex function" "ReactomePathway" "6" "8" "8" "100" "False" "" "1403" "R-HSA-9726842" "LeafAnnotation" "Gain-of-function MRAS complexes activate RAF signaling" "ReactomePathway" "6" "8" "8" "100" "False" "" "1404" "R-HSA-170968" "LeafAnnotation" "Frs2-mediated activation" "ReactomePathway" "8" "9" "11" "82" "False" "" "1405" "R-HSA-170984" "LeafAnnotation" "ARMS-mediated activation" "ReactomePathway" "4" "5" "7" "71" "False" "" "1406" "R-HSA-2408522" "IntermediateAnnotation" "Selenoamino acid metabolism" "ReactomePathway" "11" "11" "11" "100" "False" "" "1407" "R-HSA-379716" "LeafAnnotation" "Cytosolic tRNA aminoacylation" "ReactomePathway" "24" "24" "24" "100" "False" "" "1408" "R-HSA-880009" "LeafAnnotation" "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" "ReactomePathway" "2" "2" "3" "67" "False" "" "1409" "WP47" "LeafAnnotation" "Hedgehog signaling pathway" "WikiPathway" "5" "7" "16" "44" "False" "" "1410" "R-HSA-9022538" "LeafAnnotation" "Loss of MECP2 binding ability to 5mC-DNA" "ReactomePathway" "2" "2" "2" "100" "False" "" "1411" "R-HSA-197264" "LeafAnnotation" "Nicotinamide salvaging" "ReactomePathway" "8" "9" "19" "47" "False" "" "1412" "R-HSA-209563" "LeafAnnotation" "Axonal growth stimulation" "ReactomePathway" "2" "2" "4" "50" "False" "" "1413" "R-HSA-193634" "LeafAnnotation" "Axonal growth inhibition (RHOA activation)" "ReactomePathway" "3" "3" "9" "33" "False" "" "1414" "R-HSA-73843" "LeafAnnotation" "5-Phosphoribose 1-diphosphate biosynthesis" "ReactomePathway" "2" "3" "3" "100" "False" "" "1415" "WP4494" "LeafAnnotation" "Selective expression of chemokine receptors during T-cell polarization" "WikiPathway" "3" "3" "29" "10" "False" "" "1416" "WP530" "LeafAnnotation" "Cytokines and inflammatory response" "WikiPathway" "2" "2" "26" "8" "False" "" "1417" "R-HSA-202427" "LeafAnnotation" "Phosphorylation of CD3 and TCR zeta chains" "ReactomePathway" "4" "5" "28" "18" "False" "" "1418" "R-HSA-202430" "LeafAnnotation" "Translocation of ZAP-70 to Immunological synapse" "ReactomePathway" "1" "2" "25" "8" "False" "" "1419" "R-HSA-202433" "LeafAnnotation" "Generation of second messenger molecules" "ReactomePathway" "7" "9" "40" "22" "False" "" "1420" "R-HSA-167590" "LeafAnnotation" "Nef Mediated CD4 Down-regulation" "ReactomePathway" "7" "9" "9" "100" "False" "" "1421" "R-HSA-1462054" "LeafAnnotation" "Alpha-defensins" "ReactomePathway" "2" "3" "9" "33" "False" "" "1422" "R-HSA-173107" "LeafAnnotation" "Binding and entry of HIV virion" "ReactomePathway" "2" "2" "4" "50" "False" "" "1423" "R-HSA-449836" "LeafAnnotation" "Other interleukin signaling" "ReactomePathway" "11" "11" "24" "46" "False" "" "1424" "R-HSA-9752946" "LeafAnnotation" "Expression and translocation of olfactory receptors" "ReactomePathway" "1" "2" "407" "0" "False" "" "1425" "R-HSA-9678110" "LeafAnnotation" "Attachment and Entry" "ReactomePathway" "3" "3" "4" "75" "False" "" "1426" "R-HSA-5689896" "LeafAnnotation" "Ovarian tumor domain proteases" "ReactomePathway" "14" "17" "39" "44" "False" "" "1427" "R-HSA-8876725" "LeafAnnotation" "Protein methylation" "ReactomePathway" "6" "6" "16" "38" "False" "" "1428" "WP334" "LeafAnnotation" "GPCRs, class B secretin-like" "WikiPathway" "2" "3" "21" "14" "False" "" "1429" "WP2333" "LeafAnnotation" "Trans-sulfuration pathway" "WikiPathway" "8" "8" "10" "80" "False" "" "1430" "R-HSA-433692" "LeafAnnotation" "Proton-coupled monocarboxylate transport" "ReactomePathway" "4" "4" "6" "67" "False" "" "1431" "R-HSA-5627083" "LeafAnnotation" "RHO GTPases regulate CFTR trafficking" "ReactomePathway" "2" "3" "3" "100" "False" "" "1432" "R-HSA-1912399" "LeafAnnotation" "Pre-NOTCH Processing in the Endoplasmic Reticulum" "ReactomePathway" "5" "5" "6" "83" "False" "" "1433" "R-HSA-442380" "LeafAnnotation" "Zinc influx into cells by the SLC39 gene family" "ReactomePathway" "5" "5" "10" "50" "False" "" "1434" "WP3876" "LeafAnnotation" "BMP2-WNT4-FOXO1 pathway in primary endometrial stromal cell differentiation" "WikiPathway" "2" "3" "11" "27" "False" "" "1435" "R-HSA-2022870" "LeafAnnotation" "Chondroitin sulfate biosynthesis" "ReactomePathway" "8" "8" "19" "42" "False" "" "1436" "R-HSA-2022923" "LeafAnnotation" "Dermatan sulfate biosynthesis" "ReactomePathway" "5" "5" "11" "45" "False" "" "1437" "R-HSA-3595172" "LeafAnnotation" "Defective CHST3 causes SEDCJD" "ReactomePathway" "5" "5" "8" "62" "False" "" "1438" "R-HSA-3595174" "LeafAnnotation" "Defective CHST14 causes EDS, musculocontractural type" "ReactomePathway" "5" "5" "8" "62" "False" "" "1439" "R-HSA-3595177" "LeafAnnotation" "Defective CHSY1 causes TPBS" "ReactomePathway" "4" "4" "8" "50" "False" "" "1440" "WP4790" "LeafAnnotation" "FGF23 signaling in hypophosphatemic rickets and related disorders" "WikiPathway" "5" "7" "23" "30" "False" "" "1441" "R-HSA-199220" "IntermediateAnnotation" "Vitamin B5 (pantothenate) metabolism" "ReactomePathway" "3" "3" "9" "33" "False" "" "1442" "R-HSA-196843" "LeafAnnotation" "Vitamin B2 (riboflavin) metabolism" "ReactomePathway" "2" "2" "7" "29" "False" "" "1443" "WP3953" "LeafAnnotation" "mRNA, protein, and metabolite inducation pathway by cyclosporin A" "WikiPathway" "4" "4" "6" "67" "False" "" "1444" "WP5213" "LeafAnnotation" "Amino acid metabolism in triple-negative breast cancer cells" "WikiPathway" "7" "7" "7" "100" "False" "" "1445" "R-HSA-71336" "IntermediateAnnotation" "Pentose phosphate pathway" "ReactomePathway" "7" "7" "11" "64" "False" "" "1446" "R-HSA-1482922" "LeafAnnotation" "Acyl chain remodelling of PI" "ReactomePathway" "2" "2" "17" "12" "False" "" "1447" "WP4292" "LeafAnnotation" "Methionine metabolism leading to sulfur amino acids and related disorders" "WikiPathway" "2" "2" "3" "67" "False" "" "1448" "R-HSA-1614603" "LeafAnnotation" "Cysteine formation from homocysteine" "ReactomePathway" "1" "1" "2" "50" "False" "" "1449" "WP2453" "LeafAnnotation" "TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc)" "WikiPathway" "16" "16" "16" "100" "False" "" "1450" "R-HSA-169911" "IntermediateAnnotation" "Regulation of Apoptosis" "ReactomePathway" "1" "1" "2" "50" "False" "" "1451" "R-HSA-947581" "LeafAnnotation" "Molybdenum cofactor biosynthesis" "ReactomePathway" "2" "2" "5" "40" "False" "" "1452" "WP4860" "LeafAnnotation" "Hijack of ubiquitination by SARS-CoV-2" "WikiPathway" "6" "6" "8" "75" "False" "" "1453" "R-HSA-196807" "IntermediateAnnotation" "Nicotinate metabolism" "ReactomePathway" "6" "6" "12" "50" "False" "" "1454" "R-HSA-983695" "LeafAnnotation" "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" "ReactomePathway" "11" "19" "86" "22" "False" "" "1455" "R-HSA-112043" "IntermediateAnnotation" "PLC beta mediated events" "ReactomePathway" "9" "10" "12" "83" "False" "" "1456" "R-HSA-1489509" "IntermediateAnnotation" "DAG and IP3 signaling" "ReactomePathway" "6" "6" "7" "86" "False" "" "1457" "R-HSA-5690338" "LeafAnnotation" "Defective ABCC6 causes PXE" "ReactomePathway" "1" "1" "1" "100" "False" "" "1458" "WP2583" "LeafAnnotation" "T cell receptor and co-stimulatory signaling" "WikiPathway" "11" "13" "27" "48" "False" "" "1459" "WP3944" "LeafAnnotation" "Serotonin and anxiety-related events" "WikiPathway" "1" "2" "12" "17" "False" "" "1460" "WP3947" "LeafAnnotation" "Serotonin and anxiety" "WikiPathway" "2" "4" "16" "25" "False" "" "1461" "WP4482" "LeafAnnotation" "Vitamin D in inflammatory diseases" "WikiPathway" "11" "13" "22" "59" "False" "" "1462" "WP2509" "LeafAnnotation" "Nanoparticle triggered autophagic cell death" "WikiPathway" "10" "10" "22" "45" "False" "" "1463" "R-HSA-432720" "LeafAnnotation" "Lysosome Vesicle Biogenesis" "ReactomePathway" "23" "26" "34" "76" "False" "" "1464" "R-HSA-177504" "LeafAnnotation" "Retrograde neurotrophin signalling" "ReactomePathway" "10" "11" "14" "79" "False" "" "1465" "R-HSA-140837" "LeafAnnotation" "Intrinsic Pathway of Fibrin Clot Formation" "ReactomePathway" "10" "10" "23" "43" "False" "" "1466" "R-HSA-9672383" "LeafAnnotation" "Defective factor IX causes thrombophilia" "ReactomePathway" "3" "3" "3" "100" "False" "" "1467" "R-HSA-9672396" "LeafAnnotation" "Defective cofactor function of FVIIIa variant" "ReactomePathway" "3" "3" "3" "100" "False" "" "1468" "R-HSA-9673202" "LeafAnnotation" "Defective F9 variant does not activate FX" "ReactomePathway" "3" "3" "3" "100" "False" "" "1469" "R-HSA-159740" "LeafAnnotation" "Gamma-carboxylation of protein precursors" "ReactomePathway" "5" "5" "10" "50" "False" "" "1470" "R-HSA-159763" "LeafAnnotation" "Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus" "ReactomePathway" "4" "4" "9" "44" "False" "" "1471" "R-HSA-159782" "LeafAnnotation" "Removal of aminoterminal propeptides from gamma-carboxylated proteins" "ReactomePathway" "5" "5" "10" "50" "False" "" "1472" "R-HSA-140834" "LeafAnnotation" "Extrinsic Pathway of Fibrin Clot Formation" "ReactomePathway" "4" "4" "5" "80" "False" "" "1473" "R-HSA-5683329" "LeafAnnotation" "Defective ABCD4 causes MAHCJ" "ReactomePathway" "1" "1" "2" "50" "False" "" "1474" "R-HSA-9758881" "LeafAnnotation" "Uptake of dietary cobalamins into enterocytes" "ReactomePathway" "3" "3" "10" "30" "False" "" "1475" "R-HSA-9758890" "LeafAnnotation" "Transport of RCbl within the body" "ReactomePathway" "4" "4" "8" "50" "False" "" "1476" "R-HSA-351906" "LeafAnnotation" "Apoptotic cleavage of cell adhesion proteins" "ReactomePathway" "7" "7" "11" "64" "False" "" "1477" "WP4921" "LeafAnnotation" "Mitochondrial complex III assembly" "WikiPathway" "13" "13" "16" "81" "False" "" "1478" "WP5065" "LeafAnnotation" "SARS-CoV-2 altering angiogenesis via NRP1" "WikiPathway" "4" "4" "5" "80" "False" "" "1479" "R-HSA-9733458" "IntermediateAnnotation" "Induction of Cell-Cell Fusion" "ReactomePathway" "5" "5" "13" "38" "False" "" "1480" "R-HSA-1181150" "IntermediateAnnotation" "Signaling by NODAL" "ReactomePathway" "5" "6" "23" "26" "False" "" "1481" "R-HSA-1912420" "LeafAnnotation" "Pre-NOTCH Processing in Golgi" "ReactomePathway" "9" "11" "18" "61" "False" "" "1482" "R-HSA-5210891" "LeafAnnotation" "Uptake and function of anthrax toxins" "ReactomePathway" "5" "5" "6" "83" "False" "" "1483" "R-HSA-8963889" "LeafAnnotation" "Assembly of active LPL and LIPC lipase complexes" "ReactomePathway" "3" "3" "17" "18" "False" "" "1484" "R-HSA-167060" "LeafAnnotation" "NGF processing" "ReactomePathway" "1" "1" "4" "25" "False" "" "1485" "R-HSA-171286" "LeafAnnotation" "Synthesis and processing of ENV and VPU" "ReactomePathway" "1" "1" "1" "100" "False" "" "1486" "R-HSA-9662834" "LeafAnnotation" "CD163 mediating an anti-inflammatory response" "ReactomePathway" "4" "4" "9" "44" "False" "" "1487" "WP206" "LeafAnnotation" "Fatty acid omega-oxidation" "WikiPathway" "2" "5" "14" "36" "False" "" "1488" "R-HSA-71384" "LeafAnnotation" "Ethanol oxidation" "ReactomePathway" "4" "7" "10" "70" "False" "" "1489" "R-HSA-1663150" "LeafAnnotation" "The activation of arylsulfatases" "ReactomePathway" "7" "7" "13" "54" "False" "" "1490" "R-HSA-5357609" "LeafAnnotation" "Glycogen storage disease type II (GAA)" "ReactomePathway" "2" "2" "2" "100" "False" "" "1491" "R-HSA-209543" "LeafAnnotation" "p75NTR recruits signalling complexes" "ReactomePathway" "8" "11" "13" "85" "False" "" "1492" "WP3593" "LeafAnnotation" "MicroRNA for targeting cancer growth and vascularization in glioblastoma" "WikiPathway" "2" "2" "7" "29" "False" "" "1493" "R-HSA-194313" "IntermediateAnnotation" "VEGF ligand-receptor interactions" "ReactomePathway" "1" "1" "5" "20" "False" "" "1494" "WP5120" "LeafAnnotation" "Inclusion body myositis" "WikiPathway" "5" "6" "11" "55" "False" "" "1495" "R-HSA-2122948" "LeafAnnotation" "Activated NOTCH1 Transmits Signal to the Nucleus" "ReactomePathway" "12" "16" "30" "53" "False" "" "1496" "R-HSA-2979096" "LeafAnnotation" "NOTCH2 Activation and Transmission of Signal to the Nucleus" "ReactomePathway" "8" "12" "21" "57" "False" "" "1497" "R-HSA-205043" "LeafAnnotation" "NRIF signals cell death from the nucleus" "ReactomePathway" "6" "10" "16" "62" "False" "" "1498" "R-HSA-193692" "LeafAnnotation" "Regulated proteolysis of p75NTR" "ReactomePathway" "7" "8" "11" "73" "False" "" "1499" "R-HSA-9017802" "LeafAnnotation" "Noncanonical activation of NOTCH3" "ReactomePathway" "5" "6" "8" "75" "False" "" "1500" "R-HSA-3928662" "LeafAnnotation" "EPHB-mediated forward signaling" "ReactomePathway" "28" "33" "41" "80" "False" "" "1501" "R-HSA-418890" "LeafAnnotation" "Role of second messengers in netrin-1 signaling" "ReactomePathway" "2" "2" "9" "22" "False" "" "1502" "R-HSA-112308" "LeafAnnotation" "Presynaptic depolarization and calcium channel opening" "ReactomePathway" "2" "3" "11" "27" "False" "" "1503" "R-HSA-8941237" "LeafAnnotation" "Invadopodia formation" "ReactomePathway" "2" "2" "4" "50" "False" "" "1504" "R-HSA-5423646" "LeafAnnotation" "Aflatoxin activation and detoxification" "ReactomePathway" "6" "8" "20" "40" "False" "" "1505" "R-HSA-9753281" "LeafAnnotation" "Paracetamol ADME" "ReactomePathway" "11" "11" "28" "39" "False" "" "1506" "R-HSA-5579007" "LeafAnnotation" "Defective ACY1 causes encephalopathy" "ReactomePathway" "1" "1" "1" "100" "False" "" "1507" "WP106" "LeafAnnotation" "Alanine and aspartate metabolism" "WikiPathway" "7" "7" "12" "58" "False" "" "1508" "WP4856" "LeafAnnotation" "Intracellular trafficking proteins involved in CMT neuropathy" "WikiPathway" "16" "19" "27" "70" "False" "" "1509" "R-HSA-3928664" "LeafAnnotation" "Ephrin signaling" "ReactomePathway" "10" "15" "18" "83" "False" "" "1510" "R-HSA-4641263" "LeafAnnotation" "Regulation of FZD by ubiquitination" "ReactomePathway" "3" "6" "21" "29" "False" "" "1511" "R-HSA-5340588" "LeafAnnotation" "Signaling by RNF43 mutants" "ReactomePathway" "2" "2" "8" "25" "False" "" "1512" "WP4966" "LeafAnnotation" "Fluoroacetic acid toxicity" "WikiPathway" "6" "6" "6" "100" "False" "" "1513" "WP3" "LeafAnnotation" "Transcriptional activation by NRF2 in response to phytochemicals" "WikiPathway" "9" "9" "15" "60" "False" "" "1514" "WP4357" "LeafAnnotation" "NRF2-ARE regulation" "WikiPathway" "14" "15" "23" "65" "False" "" "1515" "WP5113" "LeafAnnotation" "Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway" "WikiPathway" "12" "13" "31" "42" "False" "" "1516" "R-HSA-9707587" "LeafAnnotation" "Regulation of HMOX1 expression and activity" "ReactomePathway" "3" "3" "5" "60" "False" "" "1517" "R-HSA-9818027" "IntermediateAnnotation" "NFE2L2 regulating anti-oxidant/detoxification enzymes" "ReactomePathway" "8" "8" "16" "50" "False" "" "1518" "R-HSA-844456" "LeafAnnotation" "The NLRP3 inflammasome" "ReactomePathway" "11" "11" "16" "69" "False" "" "1519" "R-HSA-9660826" "LeafAnnotation" "Purinergic signaling in leishmaniasis infection" "ReactomePathway" "14" "14" "26" "54" "False" "" "1520" "R-HSA-1483206" "IntermediateAnnotation" "Glycerophospholipid biosynthesis" "ReactomePathway" "4" "5" "5" "100" "False" "" "1521" "WP4767" "LeafAnnotation" "FGFR3 signaling in chondrocyte proliferation and terminal differentiation" "WikiPathway" "12" "14" "27" "52" "False" "" "1522" "R-HSA-8849471" "LeafAnnotation" "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases" "ReactomePathway" "11" "12" "13" "92" "False" "" "1523" "WP5169" "LeafAnnotation" "Hemesynthesis defects and porphyrias" "WikiPathway" "6" "6" "9" "67" "False" "" "1524" "WP561" "LeafAnnotation" "Heme biosynthesis" "WikiPathway" "6" "6" "9" "67" "False" "" "1525" "R-HSA-879415" "LeafAnnotation" "Advanced glycosylation endproduct receptor signaling" "ReactomePathway" "9" "9" "13" "69" "False" "" "1526" "WP2874" "LeafAnnotation" "Liver X receptor pathway" "WikiPathway" "2" "2" "10" "20" "False" "" "1527" "WP4724" "LeafAnnotation" "Omega-9 fatty acid synthesis" "WikiPathway" "7" "8" "12" "67" "False" "" "1528" "WP5066" "LeafAnnotation" "FOXA2 pathway" "WikiPathway" "5" "5" "16" "31" "False" "" "1529" "R-HSA-9029558" "LeafAnnotation" "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" "ReactomePathway" "2" "3" "8" "38" "False" "" "1530" "WP3858" "LeafAnnotation" "Toll-like receptor signaling related to MyD88" "WikiPathway" "12" "13" "31" "42" "False" "" "1531" "WP3877" "LeafAnnotation" "MYD88 distinct input-output pathway" "WikiPathway" "6" "6" "17" "35" "False" "" "1532" "WP4136" "LeafAnnotation" "Fibrin complement receptor 3 signaling pathway" "WikiPathway" "16" "17" "43" "40" "False" "" "1533" "WP4868" "LeafAnnotation" "Type I interferon induction and signaling during SARS-CoV-2 infection" "WikiPathway" "11" "11" "23" "48" "False" "" "1534" "R-HSA-166058" "IntermediateAnnotation" "MyD88:MAL(TIRAP) cascade initiated on plasma membrane" "ReactomePathway" "11" "12" "26" "46" "False" "" "1535" "R-HSA-5602498" "LeafAnnotation" "MyD88 deficiency (TLR2/4)" "ReactomePathway" "8" "9" "17" "53" "False" "" "1536" "R-HSA-5603041" "LeafAnnotation" "IRAK4 deficiency (TLR2/4)" "ReactomePathway" "8" "9" "18" "50" "False" "" "1537" "R-HSA-1810476" "LeafAnnotation" "RIP-mediated NFkB activation via ZBP1" "ReactomePathway" "9" "10" "17" "59" "False" "" "1538" "R-HSA-975138" "IntermediateAnnotation" "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" "ReactomePathway" "4" "4" "9" "44" "False" "" "1539" "R-HSA-975155" "IntermediateAnnotation" "MyD88 dependent cascade initiated on endosome" "ReactomePathway" "3" "3" "7" "43" "False" "" "1540" "R-HSA-975871" "IntermediateAnnotation" "MyD88 cascade initiated on plasma membrane" "ReactomePathway" "4" "4" "9" "44" "False" "" "1541" "R-HSA-5602680" "LeafAnnotation" "MyD88 deficiency (TLR5)" "ReactomePathway" "1" "1" "2" "50" "False" "" "1542" "R-HSA-5603037" "LeafAnnotation" "IRAK4 deficiency (TLR5)" "ReactomePathway" "1" "1" "4" "25" "False" "" "1543" "R-HSA-975110" "LeafAnnotation" "TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling" "ReactomePathway" "6" "9" "13" "69" "False" "" "1544" "R-HSA-3134963" "LeafAnnotation" "DEx/H-box helicases activate type I IFN and inflammatory cytokines production" "ReactomePathway" "6" "6" "7" "86" "False" "" "1545" "WP5033" "LeafAnnotation" "Genes associated with the development of rheumatoid arthritis" "WikiPathway" "4" "5" "18" "28" "False" "" "1546" "R-HSA-6788467" "LeafAnnotation" "IL-6-type cytokine receptor ligand interactions" "ReactomePathway" "4" "4" "17" "24" "False" "" "1547" "R-HSA-70921" "LeafAnnotation" "Histidine catabolism" "ReactomePathway" "1" "1" "8" "12" "False" "" "1548" "R-HSA-6814848" "LeafAnnotation" "Glycerophospholipid catabolism" "ReactomePathway" "3" "4" "7" "57" "False" "" "1549" "R-HSA-2424491" "LeafAnnotation" "DAP12 signaling" "ReactomePathway" "8" "12" "23" "52" "False" "" "1550" "R-HSA-1433559" "LeafAnnotation" "Regulation of KIT signaling" "ReactomePathway" "4" "7" "13" "54" "False" "" "1551" "R-HSA-389356" "IntermediateAnnotation" "CD28 co-stimulation" "ReactomePathway" "2" "4" "8" "50" "False" "" "1552" "R-HSA-389359" "LeafAnnotation" "CD28 dependent Vav1 pathway" "ReactomePathway" "4" "7" "11" "64" "False" "" "1553" "R-HSA-164944" "LeafAnnotation" "Nef and signal transduction" "ReactomePathway" "2" "6" "7" "86" "False" "" "1554" "R-HSA-9706374" "LeafAnnotation" "FLT3 signaling through SRC family kinases" "ReactomePathway" "0" "4" "6" "67" "False" "" "1555" "R-HSA-162710" "LeafAnnotation" "Synthesis of glycosylphosphatidylinositol (GPI)" "ReactomePathway" "2" "2" "17" "12" "False" "" "1556" "R-HSA-9673240" "LeafAnnotation" "Defective gamma-carboxylation of F9" "ReactomePathway" "2" "2" "2" "100" "False" "" "1557" "R-HSA-975577" "LeafAnnotation" "N-Glycan antennae elongation" "ReactomePathway" "4" "4" "15" "27" "False" "" "1558" "R-HSA-5579026" "LeafAnnotation" "Defective CYP11A1 causes AICSR" "ReactomePathway" "3" "3" "4" "75" "False" "" "1559" "R-HSA-2395516" "LeafAnnotation" "Electron transport from NADPH to Ferredoxin" "ReactomePathway" "3" "3" "3" "100" "False" "" "1560" "R-HSA-5205685" "LeafAnnotation" "PINK1-PRKN Mediated Mitophagy" "ReactomePathway" "12" "16" "22" "73" "False" "" "1561" "WP3300" "LeafAnnotation" "Dual hijack model of Vif in HIV infection" "WikiPathway" "4" "5" "8" "62" "False" "" "1562" "WP129" "LeafAnnotation" "Matrix metalloproteinases" "WikiPathway" "8" "8" "30" "27" "False" "" "1563" "R-HSA-446107" "LeafAnnotation" "Type I hemidesmosome assembly" "ReactomePathway" "6" "6" "10" "60" "False" "" "1564" "R-HSA-428543" "LeafAnnotation" "Inactivation of CDC42 and RAC1" "ReactomePathway" "5" "6" "8" "75" "False" "" "1565" "WP3630" "LeafAnnotation" "NAD metabolism, sirtuins and aging" "WikiPathway" "5" "5" "11" "45" "False" "" "1566" "WP3644" "LeafAnnotation" "NAD+ metabolism" "WikiPathway" "6" "6" "16" "38" "False" "" "1567" "WP3645" "LeafAnnotation" "NAD+ biosynthetic pathways" "WikiPathway" "9" "9" "22" "41" "False" "" "1568" "R-HSA-9617629" "LeafAnnotation" "Regulation of FOXO transcriptional activity by acetylation" "ReactomePathway" "3" "3" "10" "30" "False" "" "1569" "WP4760" "LeafAnnotation" "PKC-gamma calcium signaling pathway in ataxia" "WikiPathway" "11" "13" "21" "62" "False" "" "1570" "WP5191" "LeafAnnotation" "Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution" "WikiPathway" "3" "3" "6" "50" "False" "" "1571" "R-HSA-2559585" "LeafAnnotation" "Oncogene Induced Senescence" "ReactomePathway" "9" "15" "34" "44" "False" "" "1572" "WP3879" "LeafAnnotation" "4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression" "WikiPathway" "9" "11" "17" "65" "False" "" "1573" "WP4269" "LeafAnnotation" "Ethanol metabolism production of ROS by CYP2E1" "WikiPathway" "3" "3" "9" "33" "False" "" "1574" "R-HSA-5674499" "LeafAnnotation" "Negative feedback regulation of MAPK pathway" "ReactomePathway" "4" "6" "6" "100" "False" "" "1575" "R-HSA-9652169" "LeafAnnotation" "Signaling by MAP2K mutants" "ReactomePathway" "4" "4" "4" "100" "False" "" "1576" "R-HSA-75153" "IntermediateAnnotation" "Apoptotic execution phase" "ReactomePathway" "3" "3" "4" "75" "False" "" "1577" "R-HSA-977347" "LeafAnnotation" "Serine biosynthesis" "ReactomePathway" "8" "8" "9" "89" "False" "" "1578" "WP4962" "LeafAnnotation" "Airway smooth muscle cell contraction" "WikiPathway" "9" "9" "15" "60" "False" "" "1579" "WP2406" "LeafAnnotation" "Cardiac progenitor differentiation" "WikiPathway" "11" "14" "52" "27" "False" "" "1580" "WP4141" "LeafAnnotation" "PI3K/AKT/mTOR - vitamin D3 signaling" "WikiPathway" "10" "12" "22" "55" "False" "" "1581" "WP4297" "LeafAnnotation" "Thiamine metabolic pathways" "WikiPathway" "3" "3" "8" "38" "False" "" "1582" "WP528" "LeafAnnotation" "Acetylcholine synthesis" "WikiPathway" "2" "3" "7" "43" "False" "" "1583" "R-HSA-193368" "LeafAnnotation" "Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol" "ReactomePathway" "6" "9" "23" "39" "False" "" "1584" "R-HSA-2046106" "LeafAnnotation" "alpha-linolenic acid (ALA) metabolism" "ReactomePathway" "9" "9" "12" "75" "False" "" "1585" "R-HSA-389887" "LeafAnnotation" "Beta-oxidation of pristanoyl-CoA" "ReactomePathway" "6" "6" "8" "75" "False" "" "1586" "WP299" "LeafAnnotation" "Nuclear receptors in lipid metabolism and toxicity" "WikiPathway" "4" "4" "33" "12" "False" "" "1587" "R-HSA-937041" "LeafAnnotation" "IKK complex recruitment mediated by RIP1" "ReactomePathway" "9" "14" "22" "64" "False" "" "1588" "R-HSA-168927" "LeafAnnotation" "TICAM1, RIP1-mediated IKK complex recruitment" "ReactomePathway" "8" "13" "19" "68" "False" "" "1589" "R-HSA-936440" "LeafAnnotation" "Negative regulators of DDX58/IFIH1 signaling" "ReactomePathway" "16" "20" "35" "57" "False" "" "1590" "R-HSA-2173795" "LeafAnnotation" "Downregulation of SMAD2/3:SMAD4 transcriptional activity" "ReactomePathway" "15" "19" "29" "66" "False" "" "1591" "R-HSA-445095" "LeafAnnotation" "Interaction between L1 and Ankyrins" "ReactomePathway" "7" "10" "31" "32" "False" "" "1592" "WP430" "LeafAnnotation" "Statin inhibition of cholesterol production" "WikiPathway" "10" "10" "29" "34" "False" "" "1593" "WP4522" "LeafAnnotation" "Metabolic pathway of LDL, HDL and TG, including diseases" "WikiPathway" "2" "2" "6" "33" "False" "" "1594" "R-HSA-5682113" "LeafAnnotation" "Defective ABCA1 causes TGD" "ReactomePathway" "1" "1" "2" "50" "False" "" "1595" "R-HSA-749476" "LeafAnnotation" "RNA Polymerase III Abortive And Retractive Initiation" "ReactomePathway" "10" "10" "40" "25" "False" "" "1596" "R-HSA-76061" "LeafAnnotation" "RNA Polymerase III Transcription Initiation From Type 1 Promoter" "ReactomePathway" "8" "8" "27" "30" "False" "" "1597" "R-HSA-76066" "LeafAnnotation" "RNA Polymerase III Transcription Initiation From Type 2 Promoter" "ReactomePathway" "8" "8" "26" "31" "False" "" "1598" "R-HSA-76071" "LeafAnnotation" "RNA Polymerase III Transcription Initiation From Type 3 Promoter" "ReactomePathway" "5" "5" "27" "19" "False" "" "1599" "R-HSA-73980" "LeafAnnotation" "RNA Polymerase III Transcription Termination" "ReactomePathway" "6" "6" "22" "27" "False" "" "1600" "R-HSA-73780" "LeafAnnotation" "RNA Polymerase III Chain Elongation" "ReactomePathway" "4" "4" "17" "24" "False" "" "1601" "R-HSA-912631" "LeafAnnotation" "Regulation of signaling by CBL" "ReactomePathway" "8" "15" "21" "71" "False" "" "1602" "R-HSA-8875555" "LeafAnnotation" "MET activates RAP1 and RAC1" "ReactomePathway" "8" "8" "10" "80" "False" "" "1603" "R-HSA-8875656" "LeafAnnotation" "MET receptor recycling" "ReactomePathway" "6" "6" "9" "67" "False" "" "1604" "WP3933" "LeafAnnotation" "Kennedy pathway from sphingolipids" "WikiPathway" "7" "8" "14" "57" "False" "" "1605" "R-HSA-418885" "LeafAnnotation" "DCC mediated attractive signaling" "ReactomePathway" "10" "10" "13" "77" "False" "" "1606" "WP465" "LeafAnnotation" "Tryptophan metabolism" "WikiPathway" "10" "10" "26" "38" "False" "" "1607" "R-HSA-71064" "LeafAnnotation" "Lysine catabolism" "ReactomePathway" "6" "6" "12" "50" "False" "" "1608" "R-HSA-375280" "IntermediateAnnotation" "Amine ligand-binding receptors" "ReactomePathway" "2" "2" "8" "25" "False" "" "1609" "R-HSA-181429" "LeafAnnotation" "Serotonin Neurotransmitter Release Cycle" "ReactomePathway" "4" "6" "17" "35" "False" "" "1610" "R-HSA-181430" "LeafAnnotation" "Norepinephrine Neurotransmitter Release Cycle" "ReactomePathway" "5" "7" "17" "41" "False" "" "1611" "R-HSA-264642" "LeafAnnotation" "Acetylcholine Neurotransmitter Release Cycle" "ReactomePathway" "4" "6" "16" "38" "False" "" "1612" "R-HSA-888590" "IntermediateAnnotation" "GABA synthesis, release, reuptake and degradation" "ReactomePathway" "5" "5" "12" "42" "False" "" "1613" "R-HSA-5676934" "LeafAnnotation" "Protein repair" "ReactomePathway" "5" "5" "6" "83" "False" "" "1614" "R-HSA-2206305" "LeafAnnotation" "MPS IIID - Sanfilippo syndrome D" "ReactomePathway" "1" "1" "1" "100" "False" "" "1615" "WP3670" "LeafAnnotation" "Interactions between LOXL4 and oxidative stress pathway" "WikiPathway" "8" "8" "17" "47" "False" "" "1616" "R-HSA-9635465" "LeafAnnotation" "Suppression of apoptosis" "ReactomePathway" "5" "5" "7" "71" "False" "" "1617" "R-HSA-2161541" "LeafAnnotation" "Abacavir metabolism" "ReactomePathway" "2" "3" "4" "75" "False" "" "1618" "WP5242" "LeafAnnotation" "Comprehensive IL-17A signaling" "WikiPathway" "11" "11" "22" "50" "False" "" "1619" "R-HSA-1474244" "RootAnnotation" "Extracellular matrix organization" "ReactomePathway" "9" "10" "14" "71" "False" "" "1620" "R-HSA-1482883" "LeafAnnotation" "Acyl chain remodeling of DAG and TAG" "ReactomePathway" "2" "2" "7" "29" "False" "" "1621" "R-HSA-426048" "LeafAnnotation" "Arachidonate production from DAG" "ReactomePathway" "4" "4" "5" "80" "False" "" "1622" "WP2848" "LeafAnnotation" "Pluripotent stem cell differentiation pathway" "WikiPathway" "7" "8" "46" "17" "False" "" "1623" "WP4331" "LeafAnnotation" "Neovascularisation processes" "WikiPathway" "12" "15" "28" "54" "False" "" "1624" "R-HSA-8866910" "LeafAnnotation" "TFAP2 (AP-2) family regulates transcription of growth factors and their receptors" "ReactomePathway" "3" "4" "13" "31" "False" "" "1625" "R-HSA-9669914" "LeafAnnotation" "Dasatinib-resistant KIT mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "1626" "R-HSA-9669917" "LeafAnnotation" "Imatinib-resistant KIT mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "1627" "R-HSA-9669921" "LeafAnnotation" "KIT mutants bind TKIs" "ReactomePathway" "0" "1" "1" "100" "False" "" "1628" "R-HSA-9669924" "LeafAnnotation" "Masitinib-resistant KIT mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "1629" "R-HSA-9669926" "LeafAnnotation" "Nilotinib-resistant KIT mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "1630" "R-HSA-9669929" "LeafAnnotation" "Regorafenib-resistant KIT mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "1631" "R-HSA-9669933" "LeafAnnotation" "Signaling by kinase domain mutants of KIT" "ReactomePathway" "0" "1" "1" "100" "False" "" "1632" "R-HSA-9669934" "LeafAnnotation" "Sunitinib-resistant KIT mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "1633" "R-HSA-9669935" "LeafAnnotation" "Signaling by juxtamembrane domain KIT mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "1634" "R-HSA-9669936" "LeafAnnotation" "Sorafenib-resistant KIT mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "1635" "R-HSA-9680187" "LeafAnnotation" "Signaling by extracellular domain mutants of KIT" "ReactomePathway" "0" "1" "1" "100" "False" "" "1636" "R-HSA-933542" "LeafAnnotation" "TRAF6 mediated NF-kB activation" "ReactomePathway" "12" "13" "25" "52" "False" "" "1637" "R-HSA-933543" "LeafAnnotation" "NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10" "ReactomePathway" "7" "8" "13" "62" "False" "" "1638" "R-HSA-918233" "LeafAnnotation" "TRAF3-dependent IRF activation pathway" "ReactomePathway" "6" "6" "15" "40" "False" "" "1639" "R-HSA-933541" "LeafAnnotation" "TRAF6 mediated IRF7 activation" "ReactomePathway" "7" "7" "28" "25" "False" "" "1640" "R-HSA-5621480" "LeafAnnotation" "Dectin-2 family" "ReactomePathway" "4" "5" "29" "17" "False" "" "1641" "R-HSA-977068" "LeafAnnotation" "Termination of O-glycan biosynthesis" "ReactomePathway" "4" "4" "26" "15" "False" "" "1642" "R-HSA-5083625" "LeafAnnotation" "Defective GALNT3 causes HFTC" "ReactomePathway" "3" "3" "19" "16" "False" "" "1643" "R-HSA-5083632" "LeafAnnotation" "Defective C1GALT1C1 causes TNPS" "ReactomePathway" "4" "4" "20" "20" "False" "" "1644" "R-HSA-5083636" "LeafAnnotation" "Defective GALNT12 causes CRCS1" "ReactomePathway" "3" "3" "19" "16" "False" "" "1645" "R-HSA-4419969" "LeafAnnotation" "Depolymerisation of the Nuclear Lamina" "ReactomePathway" "8" "9" "13" "69" "False" "" "1646" "R-HSA-171007" "LeafAnnotation" "p38MAPK events" "ReactomePathway" "6" "6" "11" "55" "False" "" "1647" "R-HSA-72662" "IntermediateAnnotation" "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S" "ReactomePathway" "6" "6" "7" "86" "False" "" "1648" "WP5183" "LeafAnnotation" "SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction" "WikiPathway" "11" "11" "14" "79" "False" "" "1649" "R-HSA-174430" "LeafAnnotation" "Telomere C-strand synthesis initiation" "ReactomePathway" "3" "3" "13" "23" "False" "" "1650" "R-HSA-174414" "IntermediateAnnotation" "Processive synthesis on the C-strand of the telomere" "ReactomePathway" "3" "3" "14" "21" "False" "" "1651" "R-HSA-174417" "IntermediateAnnotation" "Telomere C-strand (Lagging Strand) Synthesis" "ReactomePathway" "3" "3" "11" "27" "False" "" "1652" "R-HSA-174437" "LeafAnnotation" "Removal of the Flap Intermediate from the C-strand" "ReactomePathway" "7" "7" "17" "41" "False" "" "1653" "WP4842" "LeafAnnotation" "Mammalian disorder of sexual development" "WikiPathway" "2" "4" "24" "17" "False" "" "1654" "WP2113" "LeafAnnotation" "Type III interferon signaling" "WikiPathway" "5" "5" "10" "50" "False" "" "1655" "WP4197" "LeafAnnotation" "Immune response to tuberculosis" "WikiPathway" "8" "9" "21" "43" "False" "" "1656" "WP4558" "LeafAnnotation" "Overview of interferons-mediated signaling pathway" "WikiPathway" "6" "7" "35" "20" "False" "" "1657" "WP4912" "LeafAnnotation" "SARS coronavirus and innate immunity" "WikiPathway" "9" "9" "29" "31" "False" "" "1658" "WP5039" "LeafAnnotation" "SARS-CoV-2 innate immunity evasion and cell-specific immune response" "WikiPathway" "20" "21" "57" "37" "False" "" "1659" "R-HSA-9013508" "LeafAnnotation" "NOTCH3 Intracellular Domain Regulates Transcription" "ReactomePathway" "7" "7" "24" "29" "False" "" "1660" "R-HSA-5682910" "LeafAnnotation" "LGI-ADAM interactions" "ReactomePathway" "2" "2" "14" "14" "False" "" "1661" "R-HSA-5250971" "LeafAnnotation" "Toxicity of botulinum toxin type C (botC)" "ReactomePathway" "1" "1" "3" "33" "False" "" "1662" "R-HSA-70895" "LeafAnnotation" "Branched-chain amino acid catabolism" "ReactomePathway" "18" "18" "21" "86" "False" "" "1663" "R-HSA-435368" "LeafAnnotation" "Zinc efflux and compartmentalization by the SLC30 family" "ReactomePathway" "2" "2" "4" "50" "False" "" "1664" "R-HSA-373760" "IntermediateAnnotation" "L1CAM interactions" "ReactomePathway" "7" "7" "13" "54" "False" "" "1665" "R-HSA-8963888" "LeafAnnotation" "Chylomicron assembly" "ReactomePathway" "5" "5" "10" "50" "False" "" "1666" "R-HSA-8963901" "LeafAnnotation" "Chylomicron remodeling" "ReactomePathway" "3" "3" "9" "33" "False" "" "1667" "R-HSA-173623" "LeafAnnotation" "Classical antibody-mediated complement activation" "ReactomePathway" "3" "7" "66" "11" "False" "" "1668" "R-HSA-2029481" "LeafAnnotation" "FCGR activation" "ReactomePathway" "4" "11" "70" "16" "False" "" "1669" "R-HSA-2454202" "IntermediateAnnotation" "Fc epsilon receptor (FCERI) signaling" "ReactomePathway" "3" "7" "62" "11" "False" "" "1670" "R-HSA-5690714" "LeafAnnotation" "CD22 mediated BCR regulation" "ReactomePathway" "4" "8" "63" "13" "False" "" "1671" "R-HSA-77288" "LeafAnnotation" "mitochondrial fatty acid beta-oxidation of unsaturated fatty acids" "ReactomePathway" "5" "5" "6" "83" "False" "" "1672" "R-HSA-9619229" "LeafAnnotation" "Activation of RAC1 downstream of NMDARs" "ReactomePathway" "3" "3" "5" "60" "False" "" "1673" "R-HSA-352238" "LeafAnnotation" "Breakdown of the nuclear lamina" "ReactomePathway" "2" "2" "2" "100" "False" "" "1674" "R-HSA-446210" "LeafAnnotation" "Synthesis of UDP-N-acetyl-glucosamine" "ReactomePathway" "7" "7" "7" "100" "False" "" "1675" "R-HSA-156584" "IntermediateAnnotation" "Cytosolic sulfonation of small molecules" "ReactomePathway" "4" "4" "16" "25" "False" "" "1676" "R-HSA-163841" "IntermediateAnnotation" "Gamma carboxylation, hypusine formation and arylsulfatase activation" "ReactomePathway" "5" "5" "6" "83" "False" "" "1677" "R-HSA-9674519" "LeafAnnotation" "Defective F8 sulfation at Y1699" "ReactomePathway" "2" "2" "3" "67" "False" "" "1678" "WP2542" "LeafAnnotation" "Sulindac metabolic pathway" "WikiPathway" "3" "3" "5" "60" "False" "" "1679" "R-HSA-5683826" "LeafAnnotation" "Surfactant metabolism" "ReactomePathway" "3" "3" "29" "10" "False" "" "1680" "R-HSA-71737" "LeafAnnotation" "Pyrophosphate hydrolysis" "ReactomePathway" "2" "2" "3" "67" "False" "" "1681" "R-HSA-525793" "LeafAnnotation" "Myogenesis" "ReactomePathway" "10" "11" "28" "39" "False" "" "1682" "R-HSA-70635" "LeafAnnotation" "Urea cycle" "ReactomePathway" "4" "4" "10" "40" "False" "" "1683" "R-HSA-9673768" "LeafAnnotation" "Signaling by membrane-tethered fusions of PDGFRA or PDGFRB" "ReactomePathway" "3" "3" "5" "60" "False" "" "1684" "WP3845" "LeafAnnotation" "Canonical and non-canonical Notch signaling" "WikiPathway" "9" "11" "27" "41" "False" "" "1685" "R-HSA-8941326" "IntermediateAnnotation" "RUNX2 regulates bone development" "ReactomePathway" "2" "2" "5" "40" "False" "" "1686" "R-HSA-74259" "IntermediateAnnotation" "Purine catabolism" "ReactomePathway" "6" "6" "10" "60" "False" "" "1687" "R-HSA-5669034" "LeafAnnotation" "TNFs bind their physiological receptors" "ReactomePathway" "3" "3" "27" "11" "False" "" "1688" "R-HSA-174403" "LeafAnnotation" "Glutathione synthesis and recycling" "ReactomePathway" "6" "6" "13" "46" "False" "" "1689" "R-HSA-5578999" "LeafAnnotation" "Defective GCLC causes HAGGSD" "ReactomePathway" "2" "2" "2" "100" "False" "" "1690" "R-HSA-6785631" "LeafAnnotation" "ERBB2 Regulates Cell Motility" "ReactomePathway" "4" "4" "13" "31" "False" "" "1691" "WP170" "LeafAnnotation" "Nuclear receptors" "WikiPathway" "3" "4" "38" "11" "False" "" "1692" "R-HSA-9617828" "LeafAnnotation" "FOXO-mediated transcription of cell cycle genes" "ReactomePathway" "3" "5" "17" "29" "False" "" "1693" "R-HSA-69895" "LeafAnnotation" "Transcriptional activation of cell cycle inhibitor p21" "ReactomePathway" "1" "2" "4" "50" "False" "" "1694" "WP4524" "LeafAnnotation" "Alternative pathway of fetal androgen synthesis" "WikiPathway" "0" "2" "8" "25" "False" "" "1695" "WP696" "LeafAnnotation" "Benzo(a)pyrene metabolism" "WikiPathway" "3" "6" "9" "67" "False" "" "1696" "R-HSA-193775" "LeafAnnotation" "Synthesis of bile acids and bile salts via 24-hydroxycholesterol" "ReactomePathway" "2" "5" "14" "36" "False" "" "1697" "R-HSA-193807" "LeafAnnotation" "Synthesis of bile acids and bile salts via 27-hydroxycholesterol" "ReactomePathway" "3" "6" "15" "40" "False" "" "1698" "R-HSA-8878166" "IntermediateAnnotation" "Transcriptional regulation by RUNX2" "ReactomePathway" "6" "6" "14" "43" "False" "" "1699" "R-HSA-9630791" "LeafAnnotation" "Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4" "ReactomePathway" "2" "2" "2" "100" "False" "" "1700" "R-HSA-9630794" "LeafAnnotation" "Evasion of Oncogene Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6" "ReactomePathway" "3" "3" "3" "100" "False" "" "1701" "R-HSA-9632697" "LeafAnnotation" "Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4" "ReactomePathway" "2" "2" "2" "100" "False" "" "1702" "R-HSA-9632700" "LeafAnnotation" "Evasion of Oxidative Stress Induced Senescence Due to Defective p16INK4A binding to CDK4 and CDK6" "ReactomePathway" "3" "3" "3" "100" "False" "" "1703" "R-HSA-9754119" "LeafAnnotation" "Drug-mediated inhibition of CDK4/CDK6 activity" "ReactomePathway" "3" "5" "5" "100" "False" "" "1704" "WP5038" "LeafAnnotation" "Mitochondrial immune response to SARS-CoV-2" "WikiPathway" "13" "13" "25" "52" "False" "" "1705" "WP5116" "LeafAnnotation" "SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation" "WikiPathway" "5" "5" "9" "56" "False" "" "1706" "R-HSA-1483115" "LeafAnnotation" "Hydrolysis of LPC" "ReactomePathway" "2" "2" "9" "22" "False" "" "1707" "R-HSA-205025" "LeafAnnotation" "NADE modulates death signalling" "ReactomePathway" "3" "3" "6" "50" "False" "" "1708" "R-HSA-418346" "IntermediateAnnotation" "Platelet homeostasis" "ReactomePathway" "2" "2" "8" "25" "False" "" "1709" "R-HSA-3299685" "LeafAnnotation" "Detoxification of Reactive Oxygen Species" "ReactomePathway" "21" "21" "35" "60" "False" "" "1710" "R-HSA-389599" "LeafAnnotation" "Alpha-oxidation of phytanate" "ReactomePathway" "1" "1" "5" "20" "False" "" "1711" "WP5149" "LeafAnnotation" "Lipid metabolism in senescent cells" "WikiPathway" "2" "3" "20" "15" "False" "" "1712" "WP5154" "LeafAnnotation" "Docosahexaenoic acid oxylipin metabolism" "WikiPathway" "0" "1" "2" "50" "False" "" "1713" "R-HSA-2142770" "LeafAnnotation" "Synthesis of 15-eicosatetraenoic acid derivatives" "ReactomePathway" "2" "3" "6" "50" "False" "" "1714" "R-HSA-9027604" "LeafAnnotation" "Biosynthesis of electrophilic ?-3 PUFA oxo-derivatives" "ReactomePathway" "0" "1" "2" "50" "False" "" "1715" "R-HSA-9018677" "IntermediateAnnotation" "Biosynthesis of DHA-derived SPMs" "ReactomePathway" "0" "1" "3" "33" "False" "" "1716" "R-HSA-9018679" "IntermediateAnnotation" "Biosynthesis of EPA-derived SPMs" "ReactomePathway" "0" "1" "1" "100" "False" "" "1717" "R-HSA-9025094" "IntermediateAnnotation" "Biosynthesis of DPAn-3 SPMs" "ReactomePathway" "0" "1" "1" "100" "False" "" "1718" "WP3679" "LeafAnnotation" "Cell-type dependent selectivity of CCK2R signaling" "WikiPathway" "5" "5" "13" "38" "False" "" "1719" "WP3958" "LeafAnnotation" "GPR40 pathway" "WikiPathway" "9" "9" "15" "60" "False" "" "1720" "R-HSA-434316" "LeafAnnotation" "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" "ReactomePathway" "4" "5" "8" "62" "False" "" "1721" "R-HSA-1855204" "LeafAnnotation" "Synthesis of IP3 and IP4 in the cytosol" "ReactomePathway" "11" "11" "25" "44" "False" "" "1722" "R-HSA-399997" "LeafAnnotation" "Acetylcholine regulates insulin secretion" "ReactomePathway" "6" "7" "10" "70" "False" "" "1723" "R-HSA-6787450" "LeafAnnotation" "tRNA modification in the mitochondrion" "ReactomePathway" "4" "4" "8" "50" "False" "" "1724" "R-HSA-8868766" "IntermediateAnnotation" "rRNA processing in the mitochondrion" "ReactomePathway" "4" "4" "4" "100" "False" "" "1725" "WP4961" "LeafAnnotation" "STING pathway in Kawasaki-like disease and COVID-19" "WikiPathway" "10" "11" "20" "55" "False" "" "1726" "R-HSA-9013973" "LeafAnnotation" "TICAM1-dependent activation of IRF3/IRF7" "ReactomePathway" "3" "6" "12" "50" "False" "" "1727" "R-HSA-3134973" "LeafAnnotation" "LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production" "ReactomePathway" "3" "3" "5" "60" "False" "" "1728" "R-HSA-1606341" "LeafAnnotation" "IRF3 mediated activation of type 1 IFN" "ReactomePathway" "2" "2" "5" "40" "False" "" "1729" "R-HSA-8850843" "LeafAnnotation" "Phosphate bond hydrolysis by NTPDase proteins" "ReactomePathway" "1" "1" "8" "12" "False" "" "1730" "R-HSA-192105" "IntermediateAnnotation" "Synthesis of bile acids and bile salts" "ReactomePathway" "4" "4" "14" "29" "False" "" "1731" "R-HSA-1483226" "LeafAnnotation" "Synthesis of PI" "ReactomePathway" "3" "3" "5" "60" "False" "" "1732" "R-HSA-211728" "LeafAnnotation" "Regulation of PAK-2p34 activity by PS-GAP/RHG10" "ReactomePathway" "2" "2" "2" "100" "False" "" "1733" "R-HSA-2408550" "LeafAnnotation" "Metabolism of ingested H2SeO4 and H2SeO3 into H2Se" "ReactomePathway" "3" "3" "3" "100" "False" "" "1734" "R-HSA-5263617" "LeafAnnotation" "Metabolism of ingested MeSeO2H into MeSeH" "ReactomePathway" "1" "1" "1" "100" "False" "" "1735" "R-HSA-8940973" "LeafAnnotation" "RUNX2 regulates osteoblast differentiation" "ReactomePathway" "9" "11" "22" "50" "False" "" "1736" "R-HSA-8935964" "LeafAnnotation" "RUNX1 regulates expression of components of tight junctions" "ReactomePathway" "2" "2" "5" "40" "False" "" "1737" "R-HSA-8931987" "LeafAnnotation" "RUNX1 regulates estrogen receptor mediated transcription" "ReactomePathway" "1" "1" "6" "17" "False" "" "1738" "R-HSA-8939256" "LeafAnnotation" "RUNX1 regulates transcription of genes involved in WNT signaling" "ReactomePathway" "1" "1" "6" "17" "False" "" "1739" "R-HSA-8877330" "LeafAnnotation" "RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)" "ReactomePathway" "1" "1" "10" "10" "False" "" "1740" "R-HSA-8939246" "LeafAnnotation" "RUNX1 regulates transcription of genes involved in differentiation of myeloid cells" "ReactomePathway" "2" "3" "6" "50" "False" "" "1741" "R-HSA-8939247" "LeafAnnotation" "RUNX1 regulates transcription of genes involved in interleukin signaling" "ReactomePathway" "1" "1" "5" "20" "False" "" "1742" "R-HSA-8941284" "LeafAnnotation" "RUNX2 regulates chondrocyte maturation" "ReactomePathway" "2" "2" "4" "50" "False" "" "1743" "R-HSA-8949275" "LeafAnnotation" "RUNX3 Regulates Immune Response and Cell Migration" "ReactomePathway" "1" "1" "5" "20" "False" "" "1744" "R-HSA-8941333" "LeafAnnotation" "RUNX2 regulates genes involved in differentiation of myeloid cells" "ReactomePathway" "2" "2" "3" "67" "False" "" "1745" "R-HSA-8939245" "LeafAnnotation" "RUNX1 regulates transcription of genes involved in BCR signaling" "ReactomePathway" "2" "3" "6" "50" "False" "" "1746" "R-HSA-8951911" "LeafAnnotation" "RUNX3 regulates RUNX1-mediated transcription" "ReactomePathway" "1" "1" "2" "50" "False" "" "1747" "R-HSA-9796292" "IntermediateAnnotation" "Formation of axial mesoderm" "ReactomePathway" "3" "4" "14" "29" "False" "" "1748" "WP288" "LeafAnnotation" "Nod-like receptor (NLR) signaling pathway" "WikiPathway" "5" "6" "9" "67" "False" "" "1749" "R-HSA-6799990" "LeafAnnotation" "Metal sequestration by antimicrobial proteins" "ReactomePathway" "4" "5" "6" "83" "False" "" "1750" "WP5109" "LeafAnnotation" "Familial hyperlipidemia type 2" "WikiPathway" "3" "3" "15" "20" "False" "" "1751" "R-HSA-196791" "LeafAnnotation" "Vitamin D (calciferol) metabolism" "ReactomePathway" "4" "4" "12" "33" "False" "" "1752" "R-HSA-8964026" "LeafAnnotation" "Chylomicron clearance" "ReactomePathway" "4" "4" "5" "80" "False" "" "1753" "R-HSA-2978092" "LeafAnnotation" "Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate" "ReactomePathway" "1" "1" "1" "100" "False" "" "1754" "R-HSA-389542" "LeafAnnotation" "NADPH regeneration" "ReactomePathway" "1" "1" "1" "100" "False" "" "1755" "R-HSA-9818025" "IntermediateAnnotation" "NFE2L2 regulating TCA cycle genes" "ReactomePathway" "2" "2" "3" "67" "False" "" "1756" "R-HSA-73817" "LeafAnnotation" "Purine ribonucleoside monophosphate biosynthesis" "ReactomePathway" "10" "10" "11" "91" "False" "" "1757" "R-HSA-113507" "LeafAnnotation" "E2F-enabled inhibition of pre-replication complex formation" "ReactomePathway" "3" "3" "9" "33" "False" "" "1758" "R-HSA-69205" "LeafAnnotation" "G1/S-Specific Transcription" "ReactomePathway" "7" "7" "28" "25" "False" "" "1759" "R-HSA-68689" "LeafAnnotation" "CDC6 association with the ORC:origin complex" "ReactomePathway" "2" "2" "8" "25" "False" "" "1760" "R-HSA-189200" "LeafAnnotation" "Cellular hexose transport" "ReactomePathway" "2" "3" "21" "14" "False" "" "1761" "R-HSA-6783984" "LeafAnnotation" "Glycine degradation" "ReactomePathway" "2" "2" "4" "50" "False" "" "1762" "R-HSA-174490" "LeafAnnotation" "Membrane binding and targetting of GAG proteins" "ReactomePathway" "9" "12" "14" "86" "False" "" "1763" "R-HSA-2514859" "LeafAnnotation" "Inactivation, recovery and regulation of the phototransduction cascade" "ReactomePathway" "7" "9" "28" "32" "False" "" "1764" "R-HSA-5684264" "LeafAnnotation" "MAP3K8 (TPL2)-dependent MAPK1/3 activation" "ReactomePathway" "8" "12" "16" "75" "False" "" "1765" "R-HSA-5358565" "LeafAnnotation" "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" "ReactomePathway" "6" "6" "14" "43" "False" "" "1766" "R-HSA-5358606" "LeafAnnotation" "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" "ReactomePathway" "5" "5" "14" "36" "False" "" "1767" "R-HSA-5632927" "LeafAnnotation" "Defective Mismatch Repair Associated With MSH3" "ReactomePathway" "1" "1" "2" "50" "False" "" "1768" "R-HSA-5632928" "LeafAnnotation" "Defective Mismatch Repair Associated With MSH2" "ReactomePathway" "2" "2" "3" "67" "False" "" "1769" "R-HSA-5632968" "LeafAnnotation" "Defective Mismatch Repair Associated With MSH6" "ReactomePathway" "2" "2" "2" "100" "False" "" "1770" "R-HSA-4549356" "LeafAnnotation" "Defective DPAGT1 causes CDG-1j, CMSTA2" "ReactomePathway" "1" "1" "1" "100" "False" "" "1771" "R-HSA-2514853" "LeafAnnotation" "Condensation of Prometaphase Chromosomes" "ReactomePathway" "8" "8" "11" "73" "False" "" "1772" "R-HSA-8934903" "LeafAnnotation" "Receptor Mediated Mitophagy" "ReactomePathway" "6" "7" "9" "78" "False" "" "1773" "R-HSA-1483191" "LeafAnnotation" "Synthesis of PC" "ReactomePathway" "12" "13" "28" "46" "False" "" "1774" "R-HSA-2980767" "LeafAnnotation" "Activation of NIMA Kinases NEK9, NEK6, NEK7" "ReactomePathway" "3" "3" "7" "43" "False" "" "1775" "R-HSA-69478" "LeafAnnotation" "G2/M DNA replication checkpoint" "ReactomePathway" "1" "1" "5" "20" "False" "" "1776" "R-HSA-1362300" "LeafAnnotation" "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" "ReactomePathway" "4" "4" "16" "25" "False" "" "1777" "R-HSA-170145" "LeafAnnotation" "Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes" "ReactomePathway" "1" "1" "3" "33" "False" "" "1778" "R-HSA-176417" "LeafAnnotation" "Phosphorylation of Emi1" "ReactomePathway" "1" "1" "6" "17" "False" "" "1779" "R-HSA-68875" "IntermediateAnnotation" "Mitotic Prophase" "ReactomePathway" "2" "2" "3" "67" "False" "" "1780" "R-HSA-6804760" "LeafAnnotation" "Regulation of TP53 Activity through Methylation" "ReactomePathway" "3" "6" "19" "32" "False" "" "1781" "WP4147" "LeafAnnotation" "PTF1A related regulatory pathway" "WikiPathway" "3" "4" "11" "36" "False" "" "1782" "R-HSA-9793380" "IntermediateAnnotation" "Formation of paraxial mesoderm" "ReactomePathway" "5" "5" "23" "22" "False" "" "1783" "R-HSA-210744" "LeafAnnotation" "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" "ReactomePathway" "3" "3" "16" "19" "False" "" "1784" "R-HSA-9013695" "LeafAnnotation" "NOTCH4 Intracellular Domain Regulates Transcription" "ReactomePathway" "7" "7" "20" "35" "False" "" "1785" "R-HSA-8941856" "LeafAnnotation" "RUNX3 regulates NOTCH signaling" "ReactomePathway" "4" "4" "14" "29" "False" "" "1786" "R-HSA-5358493" "LeafAnnotation" "Synthesis of diphthamide-EEF2" "ReactomePathway" "3" "3" "8" "38" "False" "" "1787" "R-HSA-9027276" "LeafAnnotation" "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)" "ReactomePathway" "1" "2" "12" "17" "False" "" "1788" "R-HSA-9006335" "IntermediateAnnotation" "Signaling by Erythropoietin" "ReactomePathway" "1" "1" "5" "20" "False" "" "1789" "R-HSA-9027277" "LeafAnnotation" "Erythropoietin activates Phospholipase C gamma (PLCG)" "ReactomePathway" "2" "2" "7" "29" "False" "" "1790" "R-HSA-9027283" "LeafAnnotation" "Erythropoietin activates STAT5" "ReactomePathway" "1" "1" "7" "14" "False" "" "1791" "R-HSA-75892" "LeafAnnotation" "Platelet Adhesion to exposed collagen" "ReactomePathway" "5" "6" "13" "46" "False" "" "1792" "WP1495" "LeafAnnotation" "Glycine metabolism" "WikiPathway" "1" "2" "3" "67" "False" "" "1793" "R-HSA-196757" "LeafAnnotation" "Metabolism of folate and pterines" "ReactomePathway" "7" "9" "16" "56" "False" "" "1794" "R-HSA-2691232" "LeafAnnotation" "Constitutive Signaling by NOTCH1 HD Domain Mutants" "ReactomePathway" "6" "9" "14" "64" "False" "" "1795" "R-HSA-9706369" "LeafAnnotation" "Negative regulation of FLT3" "ReactomePathway" "4" "8" "15" "53" "False" "" "1796" "R-HSA-9708530" "LeafAnnotation" "Regulation of BACH1 activity" "ReactomePathway" "4" "7" "11" "64" "False" "" "1797" "R-HSA-209560" "LeafAnnotation" "NF-kB is activated and signals survival" "ReactomePathway" "7" "10" "13" "77" "False" "" "1798" "R-HSA-937039" "LeafAnnotation" "IRAK1 recruits IKK complex" "ReactomePathway" "7" "11" "14" "79" "False" "" "1799" "R-HSA-975144" "LeafAnnotation" "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" "ReactomePathway" "7" "11" "14" "79" "False" "" "1800" "R-HSA-9636383" "LeafAnnotation" "Prevention of phagosomal-lysosomal fusion" "ReactomePathway" "6" "9" "9" "100" "False" "" "1801" "R-HSA-2173788" "LeafAnnotation" "Downregulation of TGF-beta receptor signaling" "ReactomePathway" "13" "18" "25" "72" "False" "" "1802" "R-HSA-69541" "IntermediateAnnotation" "Stabilization of p53" "ReactomePathway" "1" "4" "11" "36" "False" "" "1803" "R-HSA-3322077" "LeafAnnotation" "Glycogen synthesis" "ReactomePathway" "7" "10" "14" "71" "False" "" "1804" "R-HSA-9637628" "LeafAnnotation" "Modulation by Mtb of host immune system" "ReactomePathway" "2" "5" "7" "71" "False" "" "1805" "R-HSA-8876493" "LeafAnnotation" "InlA-mediated entry of Listeria monocytogenes into host cells" "ReactomePathway" "4" "7" "9" "78" "False" "" "1806" "R-HSA-8866427" "LeafAnnotation" "VLDLR internalisation and degradation" "ReactomePathway" "9" "12" "16" "75" "False" "" "1807" "R-HSA-3785653" "LeafAnnotation" "Myoclonic epilepsy of Lafora" "ReactomePathway" "3" "6" "9" "67" "False" "" "1808" "R-HSA-2173791" "LeafAnnotation" "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" "ReactomePathway" "5" "9" "15" "60" "False" "" "1809" "R-HSA-175474" "IntermediateAnnotation" "Assembly Of The HIV Virion" "ReactomePathway" "2" "5" "5" "100" "False" "" "1810" "R-HSA-1253288" "LeafAnnotation" "Downregulation of ERBB4 signaling" "ReactomePathway" "4" "7" "8" "88" "False" "" "1811" "R-HSA-8849469" "LeafAnnotation" "PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1" "ReactomePathway" "5" "8" "9" "89" "False" "" "1812" "R-HSA-8948747" "LeafAnnotation" "Regulation of PTEN localization" "ReactomePathway" "4" "7" "9" "78" "False" "" "1813" "R-HSA-9683683" "LeafAnnotation" "Maturation of protein E" "ReactomePathway" "1" "4" "4" "100" "False" "" "1814" "R-HSA-9694493" "LeafAnnotation" "Maturation of protein E" "ReactomePathway" "1" "4" "4" "100" "False" "" "1815" "R-HSA-9706377" "LeafAnnotation" "FLT3 signaling by CBL mutants" "ReactomePathway" "2" "6" "7" "86" "False" "" "1816" "R-HSA-383280" "LeafAnnotation" "Nuclear Receptor transcription pathway" "ReactomePathway" "3" "4" "41" "10" "False" "" "1817" "R-HSA-1368071" "LeafAnnotation" "NR1D1 (REV-ERBA) represses gene expression" "ReactomePathway" "1" "2" "3" "67" "False" "" "1818" "R-HSA-9022537" "LeafAnnotation" "Loss of MECP2 binding ability to the NCoR/SMRT complex" "ReactomePathway" "3" "5" "6" "83" "False" "" "1819" "R-HSA-9623433" "LeafAnnotation" "NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis" "ReactomePathway" "3" "3" "9" "33" "False" "" "1820" "R-HSA-399955" "LeafAnnotation" "SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion" "ReactomePathway" "6" "8" "13" "62" "False" "" "1821" "R-HSA-1306955" "LeafAnnotation" "GRB7 events in ERBB2 signaling" "ReactomePathway" "1" "1" "4" "25" "False" "" "1822" "R-HSA-1963640" "LeafAnnotation" "GRB2 events in ERBB2 signaling" "ReactomePathway" "4" "4" "13" "31" "False" "" "1823" "R-HSA-1963642" "LeafAnnotation" "PI3K events in ERBB2 signaling" "ReactomePathway" "2" "3" "13" "23" "False" "" "1824" "R-HSA-8847993" "LeafAnnotation" "ERBB2 Activates PTK6 Signaling" "ReactomePathway" "2" "2" "11" "18" "False" "" "1825" "R-HSA-1251932" "LeafAnnotation" "PLCG1 events in ERBB2 signaling" "ReactomePathway" "3" "3" "4" "75" "False" "" "1826" "R-HSA-5693548" "LeafAnnotation" "Sensing of DNA Double Strand Breaks" "ReactomePathway" "4" "4" "6" "67" "False" "" "1827" "R-HSA-2142789" "LeafAnnotation" "Ubiquinol biosynthesis" "ReactomePathway" "2" "2" "7" "29" "False" "" "1828" "WP521" "LeafAnnotation" "Amino acid conjugation of benzoic acid" "WikiPathway" "1" "1" "4" "25" "False" "" "1829" "R-HSA-2980766" "IntermediateAnnotation" "Nuclear Envelope Breakdown" "ReactomePathway" "6" "6" "6" "100" "False" "" "1830" "R-HSA-446205" "LeafAnnotation" "Synthesis of GDP-mannose" "ReactomePathway" "5" "5" "5" "100" "False" "" "1831" "R-HSA-112409" "IntermediateAnnotation" "RAF-independent MAPK1/3 activation" "ReactomePathway" "3" "3" "13" "23" "False" "" "1832" "R-HSA-2243919" "LeafAnnotation" "Crosslinking of collagen fibrils" "ReactomePathway" "12" "13" "17" "76" "False" "" "1833" "R-HSA-8849468" "LeafAnnotation" "PTK6 Regulates Proteins Involved in RNA Processing" "ReactomePathway" "3" "4" "5" "80" "False" "" "1834" "R-HSA-2142850" "LeafAnnotation" "Hyaluronan biosynthesis and export" "ReactomePathway" "3" "3" "5" "60" "False" "" "1835" "WP4159" "LeafAnnotation" "GABA receptor signaling" "WikiPathway" "7" "7" "23" "30" "False" "" "1836" "R-HSA-182218" "LeafAnnotation" "Nef Mediated CD8 Down-regulation" "ReactomePathway" "6" "6" "7" "86" "False" "" "1837" "R-HSA-5140745" "LeafAnnotation" "WNT5A-dependent internalization of FZD2, FZD5 and ROR2" "ReactomePathway" "11" "11" "13" "85" "False" "" "1838" "R-HSA-164939" "LeafAnnotation" "Nef mediated downregulation of CD28 cell surface expression" "ReactomePathway" "1" "1" "2" "50" "False" "" "1839" "WP699" "LeafAnnotation" "Aflatoxin B1 metabolism" "WikiPathway" "4" "5" "8" "62" "False" "" "1840" "R-HSA-8849473" "LeafAnnotation" "PTK6 Expression" "ReactomePathway" "2" "2" "5" "40" "False" "" "1841" "WP516" "LeafAnnotation" "Hypertrophy model" "WikiPathway" "7" "7" "20" "35" "False" "" "1842" "R-HSA-176974" "LeafAnnotation" "Unwinding of DNA" "ReactomePathway" "6" "6" "12" "50" "False" "" "1843" "R-HSA-69052" "IntermediateAnnotation" "Switching of origins to a post-replicative state" "ReactomePathway" "6" "6" "8" "75" "False" "" "1844" "R-HSA-4043916" "LeafAnnotation" "Defective MPI causes MPI-CDG" "ReactomePathway" "1" "1" "1" "100" "False" "" "1845" "R-HSA-2453864" "IntermediateAnnotation" "Retinoid cycle disease events" "ReactomePathway" "0" "1" "11" "9" "False" "" "1846" "WP186" "LeafAnnotation" "Homologous recombination" "WikiPathway" "4" "4" "12" "33" "False" "" "1847" "WP2942" "LeafAnnotation" "DDX1 as a regulatory component of the Drosha microprocessor" "WikiPathway" "4" "4" "7" "57" "False" "" "1848" "R-HSA-5693568" "LeafAnnotation" "Resolution of D-loop Structures through Holliday Junction Intermediates" "ReactomePathway" "3" "3" "32" "9" "False" "" "1849" "R-HSA-5693616" "LeafAnnotation" "Presynaptic phase of homologous DNA pairing and strand exchange" "ReactomePathway" "8" "8" "39" "21" "False" "" "1850" "R-HSA-5693554" "LeafAnnotation" "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" "ReactomePathway" "3" "3" "26" "12" "False" "" "1851" "R-HSA-5693579" "IntermediateAnnotation" "Homologous DNA Pairing and Strand Exchange" "ReactomePathway" "3" "3" "25" "12" "False" "" "1852" "R-HSA-9701192" "LeafAnnotation" "Defective homologous recombination repair (HRR) due to BRCA1 loss of function" "ReactomePathway" "3" "3" "24" "12" "False" "" "1853" "R-HSA-9704331" "LeafAnnotation" "Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function" "ReactomePathway" "3" "3" "24" "12" "False" "" "1854" "R-HSA-9704646" "LeafAnnotation" "Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function" "ReactomePathway" "3" "3" "24" "12" "False" "" "1855" "R-HSA-9709603" "LeafAnnotation" "Impaired BRCA2 binding to PALB2" "ReactomePathway" "3" "3" "23" "13" "False" "" "1856" "R-HSA-5685938" "LeafAnnotation" "HDR through Single Strand Annealing (SSA)" "ReactomePathway" "9" "9" "37" "24" "False" "" "1857" "R-HSA-9709570" "LeafAnnotation" "Impaired BRCA2 binding to RAD51" "ReactomePathway" "8" "8" "34" "24" "False" "" "1858" "R-HSA-5685939" "LeafAnnotation" "HDR through MMEJ (alt-NHEJ)" "ReactomePathway" "5" "5" "10" "50" "False" "" "1859" "R-HSA-164940" "LeafAnnotation" "Nef mediated downregulation of MHC class I complex cell surface expression" "ReactomePathway" "7" "8" "9" "89" "False" "" "1860" "R-HSA-428643" "LeafAnnotation" "Organic anion transporters" "ReactomePathway" "3" "4" "10" "40" "False" "" "1861" "WP1602" "LeafAnnotation" "Nicotine effect on dopaminergic neurons" "WikiPathway" "5" "5" "20" "25" "False" "" "1862" "WP4904" "LeafAnnotation" "LDLRAD4 and what we know about it" "WikiPathway" "3" "4" "7" "57" "False" "" "1863" "R-HSA-139915" "LeafAnnotation" "Activation of PUMA and translocation to mitochondria" "ReactomePathway" "1" "1" "9" "11" "False" "" "1864" "R-HSA-6803205" "LeafAnnotation" "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" "ReactomePathway" "6" "6" "14" "43" "False" "" "1865" "R-HSA-9632974" "LeafAnnotation" "NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis" "ReactomePathway" "1" "2" "5" "40" "False" "" "1866" "R-HSA-2206308" "LeafAnnotation" "MPS IV - Morquio syndrome B" "ReactomePathway" "1" "1" "1" "100" "False" "" "1867" "WP3849" "LeafAnnotation" "MAPK and NFkB signaling pathways inhibited by Yersinia YopJ" "WikiPathway" "6" "8" "8" "100" "False" "" "1868" "WP58" "LeafAnnotation" "Monoamine GPCRs" "WikiPathway" "2" "2" "31" "6" "False" "" "1869" "R-HSA-390650" "LeafAnnotation" "Histamine receptors" "ReactomePathway" "1" "1" "4" "25" "False" "" "1870" "R-HSA-4641265" "LeafAnnotation" "Repression of WNT target genes" "ReactomePathway" "4" "4" "12" "33" "False" "" "1871" "R-HSA-390648" "LeafAnnotation" "Muscarinic acetylcholine receptors" "ReactomePathway" "1" "1" "5" "20" "False" "" "1872" "R-HSA-1300642" "LeafAnnotation" "Sperm Motility And Taxes" "ReactomePathway" "1" "1" "9" "11" "False" "" "1873" "R-HSA-193681" "LeafAnnotation" "Ceramide signalling" "ReactomePathway" "1" "1" "3" "33" "False" "" "1874" "R-HSA-5626978" "LeafAnnotation" "TNFR1-mediated ceramide production" "ReactomePathway" "3" "3" "6" "50" "False" "" "1875" "R-HSA-5686938" "LeafAnnotation" "Regulation of TLR by endogenous ligand" "ReactomePathway" "9" "9" "20" "45" "False" "" "1876" "R-HSA-5668599" "LeafAnnotation" "RHO GTPases Activate NADPH Oxidases" "ReactomePathway" "12" "13" "24" "54" "False" "" "1877" "R-HSA-9706019" "LeafAnnotation" "RHOBTB3 ATPase cycle" "ReactomePathway" "5" "6" "9" "67" "False" "" "1878" "R-HSA-3000471" "LeafAnnotation" "Scavenging by Class B Receptors" "ReactomePathway" "2" "2" "5" "40" "False" "" "1879" "WP4853" "LeafAnnotation" "Linoleic acid metabolism affected by SARS-CoV-2" "WikiPathway" "2" "3" "5" "60" "False" "" "1880" "R-HSA-2046105" "LeafAnnotation" "Linoleic acid (LA) metabolism" "ReactomePathway" "5" "5" "8" "62" "False" "" "1881" "R-HSA-1855167" "LeafAnnotation" "Synthesis of pyrophosphates in the cytosol" "ReactomePathway" "3" "5" "10" "50" "False" "" "1882" "WP4484" "LeafAnnotation" "Control of immune tolerance by vasoactive intestinal peptide" "WikiPathway" "1" "1" "13" "8" "False" "" "1883" "WP5111" "LeafAnnotation" "Familial hyperlipidemia type 4" "WikiPathway" "5" "5" "19" "26" "False" "" "1884" "WP5284" "LeafAnnotation" "Cell interactions of the pancreatic cancer microenvironment" "WikiPathway" "5" "6" "25" "24" "False" "" "1885" "R-HSA-140534" "IntermediateAnnotation" "Caspase activation via Death Receptors in the presence of ligand" "ReactomePathway" "6" "6" "15" "40" "False" "" "1886" "R-HSA-3371378" "LeafAnnotation" "Regulation by c-FLIP" "ReactomePathway" "5" "5" "10" "50" "False" "" "1887" "R-HSA-5213460" "IntermediateAnnotation" "RIPK1-mediated regulated necrosis" "ReactomePathway" "11" "11" "21" "52" "False" "" "1888" "R-HSA-5218900" "LeafAnnotation" "CASP8 activity is inhibited" "ReactomePathway" "5" "5" "10" "50" "False" "" "1889" "R-HSA-69416" "LeafAnnotation" "Dimerization of procaspase-8" "ReactomePathway" "5" "5" "10" "50" "False" "" "1890" "R-HSA-75157" "LeafAnnotation" "FasL/ CD95L signaling" "ReactomePathway" "2" "2" "5" "40" "False" "" "1891" "WP4479" "LeafAnnotation" "Supression of HMGB1 mediated inflammation by THBD" "WikiPathway" "5" "6" "9" "67" "False" "" "1892" "WP4480" "LeafAnnotation" "Altered glycosylation of MUC1 in tumor microenvironment" "WikiPathway" "4" "5" "9" "56" "False" "" "1893" "WP4562" "LeafAnnotation" "Canonical NF-kB pathway" "WikiPathway" "4" "5" "8" "62" "False" "" "1894" "R-HSA-5602636" "LeafAnnotation" "IKBKB deficiency causes SCID" "ReactomePathway" "2" "3" "3" "100" "False" "" "1895" "R-HSA-5603027" "LeafAnnotation" "IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)" "ReactomePathway" "2" "3" "3" "100" "False" "" "1896" "R-HSA-5603029" "LeafAnnotation" "IkBA variant leads to EDA-ID" "ReactomePathway" "5" "6" "7" "86" "False" "" "1897" "R-HSA-447041" "LeafAnnotation" "CHL1 interactions" "ReactomePathway" "6" "6" "8" "75" "False" "" "1898" "R-HSA-9636467" "LeafAnnotation" "Blockage of phagosome acidification" "ReactomePathway" "1" "1" "1" "100" "False" "" "1899" "WP4157" "LeafAnnotation" "GABA metabolism (aka GHB)" "WikiPathway" "0" "1" "1" "100" "False" "" "1900" "R-HSA-141333" "LeafAnnotation" "Biogenic amines are oxidatively deaminated to aldehydes by MAOA and MAOB" "ReactomePathway" "1" "2" "2" "100" "False" "" "1901" "WP4876" "LeafAnnotation" "Activation of NLRP3 inflammasome by SARS-CoV-2" "WikiPathway" "3" "3" "6" "50" "False" "" "1902" "WP5088" "LeafAnnotation" "Prostaglandin signaling" "WikiPathway" "3" "3" "27" "11" "False" "" "1903" "R-HSA-844615" "LeafAnnotation" "The AIM2 inflammasome" "ReactomePathway" "1" "1" "3" "33" "False" "" "1904" "R-HSA-448706" "LeafAnnotation" "Interleukin-1 processing" "ReactomePathway" "4" "4" "9" "44" "False" "" "1905" "R-HSA-844623" "LeafAnnotation" "The IPAF inflammasome" "ReactomePathway" "1" "1" "2" "50" "False" "" "1906" "R-HSA-8949664" "LeafAnnotation" "Processing of SMDT1" "ReactomePathway" "14" "14" "16" "88" "False" "" "1907" "R-HSA-211897" "IntermediateAnnotation" "Cytochrome P450 - arranged by substrate type" "ReactomePathway" "1" "1" "1" "100" "False" "" "1908" "WP4228" "LeafAnnotation" "Vitamin B6-dependent and responsive disorders" "WikiPathway" "2" "2" "5" "40" "False" "" "1909" "WP4519" "LeafAnnotation" "Cerebral organic acidurias, including diseases" "WikiPathway" "3" "3" "3" "100" "False" "" "1910" "R-HSA-6798163" "LeafAnnotation" "Choline catabolism" "ReactomePathway" "2" "2" "6" "33" "False" "" "1911" "R-HSA-5660489" "LeafAnnotation" "MTF1 activates gene expression" "ReactomePathway" "1" "1" "3" "33" "False" "" "1912" "WP3674" "LeafAnnotation" "Tgif disruption of Shh signaling" "WikiPathway" "0" "2" "9" "22" "False" "" "1913" "WP5103" "LeafAnnotation" "Progeria-associated lipodystrophy" "WikiPathway" "11" "12" "19" "63" "False" "" "1914" "R-HSA-9754189" "IntermediateAnnotation" "Germ layer formation at gastrulation" "ReactomePathway" "3" "4" "17" "24" "False" "" "1915" "R-HSA-1502540" "IntermediateAnnotation" "Signaling by Activin" "ReactomePathway" "4" "5" "13" "38" "False" "" "1916" "R-HSA-3304356" "LeafAnnotation" "SMAD2/3 Phosphorylation Motif Mutants in Cancer" "ReactomePathway" "2" "3" "5" "60" "False" "" "1917" "R-HSA-3656532" "LeafAnnotation" "TGFBR1 KD Mutants in Cancer" "ReactomePathway" "2" "3" "5" "60" "False" "" "1918" "R-HSA-3311021" "LeafAnnotation" "SMAD4 MH2 Domain Mutants in Cancer" "ReactomePathway" "1" "2" "3" "67" "False" "" "1919" "R-HSA-3315487" "LeafAnnotation" "SMAD2/3 MH2 Domain Mutants in Cancer" "ReactomePathway" "1" "2" "3" "67" "False" "" "1920" "WP4661" "LeafAnnotation" "Amino acid metabolism pathway excerpt: histidine catabolism extension" "WikiPathway" "2" "2" "4" "50" "False" "" "1921" "WP136" "LeafAnnotation" "Phase I biotransformations, non P450" "WikiPathway" "4" "4" "8" "50" "False" "" "1922" "R-HSA-173736" "LeafAnnotation" "Alternative complement activation" "ReactomePathway" "1" "1" "5" "20" "False" "" "1923" "R-HSA-212718" "LeafAnnotation" "EGFR interacts with phospholipase C-gamma" "ReactomePathway" "2" "2" "9" "22" "False" "" "1924" "R-HSA-5654219" "LeafAnnotation" "Phospholipase C-mediated cascade: FGFR1" "ReactomePathway" "2" "2" "11" "18" "False" "" "1925" "R-HSA-5654221" "LeafAnnotation" "Phospholipase C-mediated cascade; FGFR2" "ReactomePathway" "2" "2" "14" "14" "False" "" "1926" "R-HSA-5655253" "IntermediateAnnotation" "Signaling by FGFR2 in disease" "ReactomePathway" "4" "6" "22" "27" "False" "" "1927" "R-HSA-5654227" "LeafAnnotation" "Phospholipase C-mediated cascade; FGFR3" "ReactomePathway" "2" "2" "9" "22" "False" "" "1928" "R-HSA-5654228" "LeafAnnotation" "Phospholipase C-mediated cascade; FGFR4" "ReactomePathway" "2" "3" "13" "23" "False" "" "1929" "R-HSA-5655332" "IntermediateAnnotation" "Signaling by FGFR3 in disease" "ReactomePathway" "4" "6" "17" "35" "False" "" "1930" "R-HSA-5655291" "IntermediateAnnotation" "Signaling by FGFR4 in disease" "ReactomePathway" "3" "5" "9" "56" "False" "" "1931" "R-HSA-167021" "LeafAnnotation" "PLC-gamma1 signalling" "ReactomePathway" "1" "1" "3" "33" "False" "" "1932" "R-HSA-9026527" "LeafAnnotation" "Activated NTRK2 signals through PLCG1" "ReactomePathway" "1" "1" "4" "25" "False" "" "1933" "R-HSA-9034793" "LeafAnnotation" "Activated NTRK3 signals through PLCG1" "ReactomePathway" "1" "1" "3" "33" "False" "" "1934" "WP134" "LeafAnnotation" "Pentose phosphate metabolism" "WikiPathway" "6" "6" "7" "86" "False" "" "1935" "WP5043" "LeafAnnotation" "Pentose phosphate pathway in senescent cells" "WikiPathway" "2" "2" "5" "40" "False" "" "1936" "WP5049" "LeafAnnotation" "Glycolysis in senescence" "WikiPathway" "6" "6" "7" "86" "False" "" "1937" "R-HSA-9818028" "IntermediateAnnotation" "NFE2L2 regulates pentose phosphate pathway genes" "ReactomePathway" "4" "4" "8" "50" "False" "" "1938" "R-HSA-1614635" "IntermediateAnnotation" "Sulfur amino acid metabolism" "ReactomePathway" "3" "3" "6" "50" "False" "" "1939" "R-HSA-5579024" "LeafAnnotation" "Defective MAT1A causes MATD" "ReactomePathway" "1" "1" "1" "100" "False" "" "1940" "R-HSA-3656225" "LeafAnnotation" "Defective CHST6 causes MCDC1" "ReactomePathway" "1" "1" "8" "12" "False" "" "1941" "R-HSA-3656243" "LeafAnnotation" "Defective ST3GAL3 causes MCT12 and EIEE15" "ReactomePathway" "1" "1" "8" "12" "False" "" "1942" "R-HSA-3656244" "LeafAnnotation" "Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)" "ReactomePathway" "2" "2" "8" "25" "False" "" "1943" "R-HSA-964827" "LeafAnnotation" "Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2" "ReactomePathway" "3" "3" "3" "100" "False" "" "1944" "WP5218" "LeafAnnotation" "Extrafollicular and follicular B cell activation by SARS-CoV-2" "WikiPathway" "8" "9" "59" "15" "False" "" "1945" "R-HSA-2214320" "LeafAnnotation" "Anchoring fibril formation" "ReactomePathway" "6" "7" "13" "54" "False" "" "1946" "R-HSA-426117" "LeafAnnotation" "Cation-coupled Chloride cotransporters" "ReactomePathway" "4" "5" "7" "71" "False" "" "1947" "R-HSA-400511" "LeafAnnotation" "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" "ReactomePathway" "6" "6" "13" "46" "False" "" "1948" "R-HSA-422085" "LeafAnnotation" "Synthesis, secretion, and deacylation of Ghrelin" "ReactomePathway" "5" "5" "18" "28" "False" "" "1949" "R-HSA-4551295" "LeafAnnotation" "Defective ALG11 causes CDG-1p" "ReactomePathway" "1" "1" "1" "100" "False" "" "1950" "R-HSA-9013419" "LeafAnnotation" "RHOT2 GTPase cycle" "ReactomePathway" "5" "5" "7" "71" "False" "" "1951" "WP3871" "LeafAnnotation" "Valproic acid pathway" "WikiPathway" "8" "8" "12" "67" "False" "" "1952" "R-HSA-176034" "LeafAnnotation" "Interactions of Tat with host cellular proteins" "ReactomePathway" "2" "2" "2" "100" "False" "" "1953" "R-HSA-1236394" "IntermediateAnnotation" "Signaling by ERBB4" "ReactomePathway" "1" "1" "16" "6" "False" "" "1954" "R-HSA-177929" "IntermediateAnnotation" "Signaling by EGFR" "ReactomePathway" "4" "4" "13" "31" "False" "" "1955" "R-HSA-179812" "LeafAnnotation" "GRB2 events in EGFR signaling" "ReactomePathway" "3" "3" "11" "27" "False" "" "1956" "R-HSA-5638303" "LeafAnnotation" "Inhibition of Signaling by Overexpressed EGFR" "ReactomePathway" "1" "1" "8" "12" "False" "" "1957" "R-HSA-2179392" "LeafAnnotation" "EGFR Transactivation by Gastrin" "ReactomePathway" "4" "4" "7" "57" "False" "" "1958" "R-HSA-8857538" "LeafAnnotation" "PTK6 promotes HIF1A stabilization" "ReactomePathway" "1" "1" "6" "17" "False" "" "1959" "WP2597" "LeafAnnotation" "Secretion of hydrochloric acid in parietal cells" "WikiPathway" "1" "1" "4" "25" "False" "" "1960" "R-HSA-1482925" "LeafAnnotation" "Acyl chain remodelling of PG" "ReactomePathway" "3" "3" "18" "17" "False" "" "1961" "R-HSA-5576886" "LeafAnnotation" "Phase 4 - resting membrane potential" "ReactomePathway" "1" "1" "18" "6" "False" "" "1962" "R-HSA-1296053" "LeafAnnotation" "Classical Kir channels" "ReactomePathway" "1" "1" "4" "25" "False" "" "1963" "R-HSA-9729555" "LeafAnnotation" "Sensory perception of sour taste" "ReactomePathway" "1" "1" "2" "50" "False" "" "1964" "R-HSA-1369007" "LeafAnnotation" "Mitochondrial ABC transporters" "ReactomePathway" "3" "3" "4" "75" "False" "" "1965" "R-HSA-5683371" "LeafAnnotation" "Defective ABCB6 causes MCOPCB7" "ReactomePathway" "1" "1" "1" "100" "False" "" "1966" "R-HSA-204626" "LeafAnnotation" "Hypusine synthesis from eIF5A-lysine" "ReactomePathway" "3" "4" "4" "100" "False" "" "1967" "R-HSA-425393" "IntermediateAnnotation" "Transport of inorganic cations/anions and amino acids/oligopeptides" "ReactomePathway" "1" "1" "8" "12" "False" "" "1968" "R-HSA-5619067" "LeafAnnotation" "Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA)" "ReactomePathway" "1" "1" "1" "100" "False" "" "1969" "WP163" "LeafAnnotation" "Cytoplasmic ribosomal proteins" "WikiPathway" "1" "1" "1" "100" "False" "" "1970" "R-RNO-975956" "LeafAnnotation" "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" "ReactomePathway" "1" "1" "1" "100" "False" "" "1971" "R-RNO-975957" "LeafAnnotation" "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" "ReactomePathway" "1" "1" "1" "100" "False" "" "1972" "R-RNO-156827" "LeafAnnotation" "L13a-mediated translational silencing of Ceruloplasmin expression" "ReactomePathway" "1" "1" "1" "100" "False" "" "1973" "R-RNO-72689" "LeafAnnotation" "Formation of a pool of free 40S subunits" "ReactomePathway" "1" "1" "1" "100" "False" "" "1974" "R-RNO-72706" "LeafAnnotation" "GTP hydrolysis and joining of the 60S ribosomal subunit" "ReactomePathway" "1" "1" "1" "100" "False" "" "1975" "R-RNO-1799339" "LeafAnnotation" "SRP-dependent cotranslational protein targeting to membrane" "ReactomePathway" "1" "1" "1" "100" "False" "" "1976" "R-RNO-6791226" "LeafAnnotation" "Major pathway of rRNA processing in the nucleolus and cytosol" "ReactomePathway" "1" "1" "1" "100" "False" "" "1977" "R-MMU-156827" "LeafAnnotation" "L13a-mediated translational silencing of Ceruloplasmin expression" "ReactomePathway" "1" "1" "1" "100" "False" "" "1978" "R-MMU-1799339" "LeafAnnotation" "SRP-dependent cotranslational protein targeting to membrane" "ReactomePathway" "1" "1" "1" "100" "False" "" "1979" "R-MMU-6791226" "LeafAnnotation" "Major pathway of rRNA processing in the nucleolus and cytosol" "ReactomePathway" "1" "1" "1" "100" "False" "" "1980" "R-MMU-72689" "LeafAnnotation" "Formation of a pool of free 40S subunits" "ReactomePathway" "1" "1" "1" "100" "False" "" "1981" "R-MMU-72706" "LeafAnnotation" "GTP hydrolysis and joining of the 60S ribosomal subunit" "ReactomePathway" "1" "1" "1" "100" "False" "" "1982" "R-MMU-975956" "LeafAnnotation" "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" "ReactomePathway" "1" "1" "1" "100" "False" "" "1983" "R-MMU-975957" "LeafAnnotation" "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" "ReactomePathway" "1" "1" "1" "100" "False" "" "1984" "R-HSA-428890" "LeafAnnotation" "Role of ABL in ROBO-SLIT signaling" "ReactomePathway" "6" "6" "8" "75" "False" "" "1985" "R-HSA-977443" "IntermediateAnnotation" "GABA receptor activation" "ReactomePathway" "2" "2" "16" "12" "False" "" "1986" "WP4532" "LeafAnnotation" "Intraflagellar transport proteins binding to dynein" "WikiPathway" "12" "13" "27" "48" "False" "" "1987" "R-HSA-901042" "IntermediateAnnotation" "Calnexin/calreticulin cycle" "ReactomePathway" "5" "5" "5" "100" "False" "" "1988" "R-HSA-376172" "LeafAnnotation" "DSCAM interactions" "ReactomePathway" "2" "3" "11" "27" "False" "" "1989" "WP4927" "LeafAnnotation" "COVID-19, thrombosis and anticoagulation" "WikiPathway" "3" "3" "3" "100" "False" "" "1990" "R-HSA-4043911" "LeafAnnotation" "Defective PMM2 causes PMM2-CDG" "ReactomePathway" "1" "1" "1" "100" "False" "" "1991" "R-HSA-112399" "IntermediateAnnotation" "IRS-mediated signalling" "ReactomePathway" "2" "3" "6" "50" "False" "" "1992" "R-HSA-198203" "LeafAnnotation" "PI3K/AKT activation" "ReactomePathway" "3" "4" "9" "44" "False" "" "1993" "WP4317" "LeafAnnotation" "Mitochondrial fatty acid synthesis pathway" "WikiPathway" "6" "6" "6" "100" "False" "" "1994" "R-HSA-193048" "LeafAnnotation" "Androgen biosynthesis" "ReactomePathway" "2" "2" "11" "18" "False" "" "1995" "R-HSA-3359485" "LeafAnnotation" "Defective CD320 causes MMATC" "ReactomePathway" "1" "1" "2" "50" "False" "" "1996" "R-HSA-73621" "LeafAnnotation" "Pyrimidine catabolism" "ReactomePathway" "3" "4" "11" "36" "False" "" "1997" "R-HSA-168138" "IntermediateAnnotation" "Toll Like Receptor 9 (TLR9) Cascade" "ReactomePathway" "3" "3" "5" "60" "False" "" "1998" "R-HSA-1614558" "IntermediateAnnotation" "Degradation of cysteine and homocysteine" "ReactomePathway" "5" "5" "10" "50" "False" "" "1999" "R-HSA-416550" "LeafAnnotation" "Sema4D mediated inhibition of cell attachment and migration" "ReactomePathway" "5" "5" "8" "62" "False" "" "2000" "R-HSA-71240" "LeafAnnotation" "Tryptophan catabolism" "ReactomePathway" "4" "4" "14" "29" "False" "" "2001" "WP5189" "LeafAnnotation" "Copper metabolism" "WikiPathway" "3" "3" "4" "75" "False" "" "2002" "R-HSA-425410" "IntermediateAnnotation" "Metal ion SLC transporters" "ReactomePathway" "2" "2" "9" "22" "False" "" "2003" "WP5231" "LeafAnnotation" "Hippocampal synaptogenesis and neurogenesis" "WikiPathway" "4" "8" "28" "29" "False" "" "2004" "R-HSA-5576892" "LeafAnnotation" "Phase 0 - rapid depolarisation" "ReactomePathway" "4" "7" "31" "23" "False" "" "2005" "WP4925" "LeafAnnotation" "Unfolded protein response" "WikiPathway" "8" "8" "23" "35" "False" "" "2006" "R-HSA-174362" "LeafAnnotation" "Transport and synthesis of PAPS" "ReactomePathway" "3" "3" "6" "50" "False" "" "2007" "R-HSA-9020591" "IntermediateAnnotation" "Interleukin-12 signaling" "ReactomePathway" "5" "5" "10" "50" "False" "" "2008" "R-HSA-8866423" "LeafAnnotation" "VLDL assembly" "ReactomePathway" "2" "2" "5" "40" "False" "" "2009" "R-HSA-8964041" "LeafAnnotation" "LDL remodeling" "ReactomePathway" "2" "2" "5" "40" "False" "" "2010" "WP3658" "LeafAnnotation" "Wnt/beta-catenin signaling pathway in leukemia" "WikiPathway" "6" "7" "21" "33" "False" "" "2011" "R-HSA-2206291" "LeafAnnotation" "MPS IIIC - Sanfilippo syndrome C" "ReactomePathway" "1" "1" "1" "100" "False" "" "2012" "R-HSA-114508" "IntermediateAnnotation" "Effects of PIP2 hydrolysis" "ReactomePathway" "6" "7" "21" "33" "False" "" "2013" "R-HSA-9603505" "LeafAnnotation" "NTRK3 as a dependence receptor" "ReactomePathway" "2" "2" "3" "67" "False" "" "2014" "R-HSA-5661270" "LeafAnnotation" "Formation of xylulose-5-phosphate" "ReactomePathway" "3" "3" "5" "60" "False" "" "2015" "R-HSA-162592" "IntermediateAnnotation" "Integration of provirus" "ReactomePathway" "5" "5" "5" "100" "False" "" "2016" "R-HSA-175567" "LeafAnnotation" "Integration of viral DNA into host genomic DNA" "ReactomePathway" "3" "3" "3" "100" "False" "" "2017" "R-HSA-177539" "LeafAnnotation" "Autointegration results in viral DNA circles" "ReactomePathway" "3" "3" "3" "100" "False" "" "2018" "R-HSA-180689" "LeafAnnotation" "APOBEC3G mediated resistance to HIV-1 infection" "ReactomePathway" "4" "4" "4" "100" "False" "" "2019" "R-HSA-203641" "LeafAnnotation" "NOSTRIN mediated eNOS trafficking" "ReactomePathway" "3" "3" "5" "60" "False" "" "2020" "R-HSA-3238698" "LeafAnnotation" "WNT ligand biogenesis and trafficking" "ReactomePathway" "9" "9" "26" "35" "False" "" "2021" "R-HSA-114516" "LeafAnnotation" "Disinhibition of SNARE formation" "ReactomePathway" "3" "5" "5" "100" "False" "" "2022" "R-HSA-416993" "LeafAnnotation" "Trafficking of GluR2-containing AMPA receptors" "ReactomePathway" "3" "5" "13" "38" "False" "" "2023" "R-HSA-76005" "IntermediateAnnotation" "Response to elevated platelet cytosolic Ca2+" "ReactomePathway" "1" "3" "3" "100" "False" "" "2024" "WP4784" "LeafAnnotation" "Proteoglycan biosynthesis" "WikiPathway" "12" "12" "18" "67" "False" "" "2025" "WP5061" "LeafAnnotation" "Fatty acid transporters" "WikiPathway" "6" "7" "18" "39" "False" "" "2026" "R-HSA-434313" "LeafAnnotation" "Intracellular metabolism of fatty acids regulates insulin secretion" "ReactomePathway" "2" "2" "3" "67" "False" "" "2027" "WP3413" "LeafAnnotation" "NOTCH1 regulation of endothelial cell calcification" "WikiPathway" "6" "7" "17" "41" "False" "" "2028" "R-HSA-8949215" "IntermediateAnnotation" "Mitochondrial calcium ion transport" "ReactomePathway" "9" "9" "13" "69" "False" "" "2029" "R-HSA-193670" "LeafAnnotation" "p75NTR negatively regulates cell cycle via SC1" "ReactomePathway" "2" "3" "6" "50" "False" "" "2030" "WP3926" "LeafAnnotation" "ApoE and miR-146 in inflammation and atherosclerosis" "WikiPathway" "5" "5" "8" "62" "False" "" "2031" "R-HSA-209822" "LeafAnnotation" "Glycoprotein hormones" "ReactomePathway" "1" "1" "10" "10" "False" "" "2032" "R-HSA-162699" "LeafAnnotation" "Synthesis of dolichyl-phosphate mannose" "ReactomePathway" "2" "2" "3" "67" "False" "" "2033" "R-HSA-4717374" "LeafAnnotation" "Defective DPM1 causes DPM1-CDG" "ReactomePathway" "2" "2" "3" "67" "False" "" "2034" "R-HSA-4719360" "LeafAnnotation" "Defective DPM3 causes DPM3-CDG" "ReactomePathway" "2" "2" "3" "67" "False" "" "2035" "R-HSA-4719377" "LeafAnnotation" "Defective DPM2 causes DPM2-CDG" "ReactomePathway" "2" "2" "3" "67" "False" "" "2036" "WP3930" "LeafAnnotation" "EDA signaling in hair follicle development" "WikiPathway" "1" "1" "13" "8" "False" "" "2037" "R-HSA-193144" "LeafAnnotation" "Estrogen biosynthesis" "ReactomePathway" "2" "3" "6" "50" "False" "" "2038" "R-HSA-5635851" "LeafAnnotation" "GLI proteins bind promoters of Hh responsive genes to promote transcription" "ReactomePathway" "1" "2" "3" "67" "False" "" "2039" "R-HSA-139853" "LeafAnnotation" "Elevation of cytosolic Ca2+ levels" "ReactomePathway" "5" "5" "15" "33" "False" "" "2040" "WP2456" "LeafAnnotation" "HIF1A and PPARG regulation of glycolysis" "WikiPathway" "5" "5" "8" "62" "False" "" "2041" "R-HSA-8937144" "LeafAnnotation" "Aryl hydrocarbon receptor signalling" "ReactomePathway" "2" "2" "6" "33" "False" "" "2042" "R-HSA-373752" "IntermediateAnnotation" "Netrin-1 signaling" "ReactomePathway" "5" "6" "18" "33" "False" "" "2043" "R-HSA-9635644" "LeafAnnotation" "Inhibition of membrane repair" "ReactomePathway" "1" "1" "1" "100" "False" "" "2044" "R-HSA-163754" "LeafAnnotation" "Insulin effects increased synthesis of Xylulose-5-Phosphate" "ReactomePathway" "2" "2" "2" "100" "False" "" "2045" "WP4883" "LeafAnnotation" "SARS-CoV-2 and ACE2 receptor: molecular mechanisms" "WikiPathway" "2" "2" "7" "29" "False" "" "2046" "WP4891" "LeafAnnotation" "COVID-19 adverse outcome pathway" "WikiPathway" "1" "1" "15" "7" "False" "" "2047" "WP5076" "LeafAnnotation" "Soluble ACE2-mediated cell entry of SARS-CoV-2" "WikiPathway" "2" "2" "4" "50" "False" "" "2048" "WP554" "LeafAnnotation" "ACE inhibitor pathway" "WikiPathway" "3" "3" "17" "18" "False" "" "2049" "R-HSA-2022377" "LeafAnnotation" "Metabolism of Angiotensinogen to Angiotensins" "ReactomePathway" "7" "7" "18" "39" "False" "" "2050" "R-HSA-69166" "LeafAnnotation" "Removal of the Flap Intermediate" "ReactomePathway" "6" "6" "14" "43" "False" "" "2051" "R-HSA-3282872" "LeafAnnotation" "Severe congenital neutropenia type 4 (G6PC3)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2052" "WP4186" "LeafAnnotation" "Somatroph axis (GH) and its relationship to dietary restriction and aging" "WikiPathway" "3" "3" "6" "50" "False" "" "2053" "WP5192" "LeafAnnotation" "Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids" "WikiPathway" "5" "5" "10" "50" "False" "" "2054" "R-HSA-2428928" "IntermediateAnnotation" "IRS-related events triggered by IGF1R" "ReactomePathway" "2" "2" "6" "33" "False" "" "2055" "R-HSA-2404192" "IntermediateAnnotation" "Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)" "ReactomePathway" "1" "1" "4" "25" "False" "" "2056" "R-HSA-2428933" "LeafAnnotation" "SHC-related events triggered by IGF1R" "ReactomePathway" "3" "3" "6" "50" "False" "" "2057" "R-HSA-9673218" "LeafAnnotation" "Defective F9 secretion" "ReactomePathway" "1" "1" "1" "100" "False" "" "2058" "R-HSA-9673221" "LeafAnnotation" "Defective F9 activation" "ReactomePathway" "1" "1" "6" "17" "False" "" "2059" "R-HSA-1839130" "LeafAnnotation" "Signaling by activated point mutants of FGFR3" "ReactomePathway" "1" "2" "9" "22" "False" "" "2060" "R-HSA-2033515" "LeafAnnotation" "t(4;14) translocations of FGFR3" "ReactomePathway" "0" "1" "1" "100" "False" "" "2061" "R-HSA-8853334" "LeafAnnotation" "Signaling by FGFR3 fusions in cancer" "ReactomePathway" "0" "1" "1" "100" "False" "" "2062" "WP24" "LeafAnnotation" "Peptide GPCRs" "WikiPathway" "1" "1" "73" "1" "False" "" "2063" "R-HSA-388479" "LeafAnnotation" "Vasopressin-like receptors" "ReactomePathway" "1" "1" "6" "17" "False" "" "2064" "WP1584" "LeafAnnotation" "Type II diabetes mellitus" "WikiPathway" "8" "8" "21" "38" "False" "" "2065" "WP3191" "LeafAnnotation" "TSLP signaling pathway" "WikiPathway" "1" "1" "1" "100" "False" "" "2066" "WP4191" "LeafAnnotation" "Caloric restriction and aging" "WikiPathway" "4" "4" "8" "50" "False" "" "2067" "R-HSA-416700" "LeafAnnotation" "Other semaphorin interactions" "ReactomePathway" "5" "5" "18" "28" "False" "" "2068" "R-HSA-480985" "LeafAnnotation" "Synthesis of dolichyl-phosphate-glucose" "ReactomePathway" "1" "1" "2" "50" "False" "" "2069" "R-HSA-3214842" "LeafAnnotation" "HDMs demethylate histones" "ReactomePathway" "7" "8" "26" "31" "False" "" "2070" "WP5173" "LeafAnnotation" "Disorders of galactose metabolism" "WikiPathway" "9" "9" "13" "69" "False" "" "2071" "R-HSA-3814836" "LeafAnnotation" "Glycogen storage disease type XV (GYG1)" "ReactomePathway" "2" "2" "2" "100" "False" "" "2072" "R-HSA-3828062" "LeafAnnotation" "Glycogen storage disease type 0 (muscle GYS1)" "ReactomePathway" "2" "2" "2" "100" "False" "" "2073" "WP4142" "LeafAnnotation" "Metabolism of sphingolipids in ER and Golgi apparatus" "WikiPathway" "2" "2" "7" "29" "False" "" "2074" "R-HSA-9694719" "LeafAnnotation" "Maturation of protein 3a" "ReactomePathway" "2" "2" "9" "22" "False" "" "2075" "R-HSA-9683673" "LeafAnnotation" "Maturation of protein 3a" "ReactomePathway" "2" "2" "9" "22" "False" "" "2076" "R-HSA-5635838" "LeafAnnotation" "Activation of SMO" "ReactomePathway" "3" "3" "18" "17" "False" "" "2077" "R-HSA-111933" "IntermediateAnnotation" "Calmodulin induced events" "ReactomePathway" "3" "4" "4" "100" "False" "" "2078" "WP2895" "LeafAnnotation" "Differentiation of white and brown adipocyte" "WikiPathway" "2" "3" "25" "12" "False" "" "2079" "R-HSA-427601" "LeafAnnotation" "Multifunctional anion exchangers" "ReactomePathway" "2" "2" "9" "22" "False" "" "2080" "R-HSA-2485179" "LeafAnnotation" "Activation of the phototransduction cascade" "ReactomePathway" "1" "2" "10" "20" "False" "" "2081" "R-HSA-162791" "LeafAnnotation" "Attachment of GPI anchor to uPAR" "ReactomePathway" "6" "6" "7" "86" "False" "" "2082" "R-HSA-5578768" "LeafAnnotation" "Physiological factors" "ReactomePathway" "3" "3" "14" "21" "False" "" "2083" "WP2289" "LeafAnnotation" "Drug induction of bile acid pathway" "WikiPathway" "3" "3" "17" "18" "False" "" "2084" "WP678" "LeafAnnotation" "Arachidonate epoxygenase / epoxide hydrolase" "WikiPathway" "2" "2" "7" "29" "False" "" "2085" "WP4389" "LeafAnnotation" "Bile acids synthesis and enterohepatic circulation" "WikiPathway" "4" "4" "9" "44" "False" "" "2086" "R-HSA-9758919" "IntermediateAnnotation" "Epithelial-Mesenchymal Transition (EMT) during gastrulation" "ReactomePathway" "1" "1" "4" "25" "False" "" "2087" "R-HSA-1839122" "LeafAnnotation" "Signaling by activated point mutants of FGFR1" "ReactomePathway" "2" "2" "8" "25" "False" "" "2088" "R-HSA-8853336" "LeafAnnotation" "Signaling by plasma membrane FGFR1 fusions" "ReactomePathway" "2" "2" "3" "67" "False" "" "2089" "R-HSA-3642279" "LeafAnnotation" "TGFBR2 MSI Frameshift Mutants in Cancer" "ReactomePathway" "1" "1" "2" "50" "False" "" "2090" "R-HSA-3645790" "LeafAnnotation" "TGFBR2 Kinase Domain Mutants in Cancer" "ReactomePathway" "1" "1" "3" "33" "False" "" "2091" "R-HSA-3656535" "LeafAnnotation" "TGFBR1 LBD Mutants in Cancer" "ReactomePathway" "2" "2" "4" "50" "False" "" "2092" "WP1603" "LeafAnnotation" "Nicotine effect on chromaffin cells" "WikiPathway" "1" "1" "4" "25" "False" "" "2093" "R-HSA-5576893" "LeafAnnotation" "Phase 2 - plateau phase" "ReactomePathway" "2" "3" "15" "20" "False" "" "2094" "WP2813" "LeafAnnotation" "Mammary gland development pathway - Embryonic development (Stage 1 of 4)" "WikiPathway" "5" "6" "14" "43" "False" "" "2095" "WP3297" "LeafAnnotation" "EV release from cardiac cells and their functional effects" "WikiPathway" "1" "2" "7" "29" "False" "" "2096" "R-HSA-9613354" "LeafAnnotation" "Lipophagy" "ReactomePathway" "5" "7" "9" "78" "False" "" "2097" "WP2485" "LeafAnnotation" "NAD biosynthesis II (from tryptophan)" "WikiPathway" "4" "4" "8" "50" "False" "" "2098" "R-HSA-211979" "LeafAnnotation" "Eicosanoids" "ReactomePathway" "1" "1" "12" "8" "False" "" "2099" "R-HSA-5579032" "LeafAnnotation" "Defective TBXAS1 causes GHDD" "ReactomePathway" "1" "1" "1" "100" "False" "" "2100" "R-HSA-8963693" "LeafAnnotation" "Aspartate and asparagine metabolism" "ReactomePathway" "5" "5" "12" "42" "False" "" "2101" "R-HSA-418457" "LeafAnnotation" "cGMP effects" "ReactomePathway" "4" "4" "15" "27" "False" "" "2102" "WP2943" "LeafAnnotation" "Hypoxia-mediated EMT and stemness" "WikiPathway" "2" "2" "2" "100" "False" "" "2103" "R-HSA-1300645" "LeafAnnotation" "Acrosome Reaction and Sperm:Oocyte Membrane Binding" "ReactomePathway" "1" "1" "6" "17" "False" "" "2104" "WP2276" "LeafAnnotation" "Glial cell differentiation" "WikiPathway" "2" "2" "7" "29" "False" "" "2105" "WP4872" "LeafAnnotation" "MAP3K1 role in promoting and blocking gonadal determination" "WikiPathway" "4" "5" "16" "31" "False" "" "2106" "R-HSA-111995" "LeafAnnotation" "phospho-PLA2 pathway" "ReactomePathway" "1" "1" "2" "50" "False" "" "2107" "R-HSA-9652817" "LeafAnnotation" "Signaling by MAPK mutants" "ReactomePathway" "1" "1" "7" "14" "False" "" "2108" "R-HSA-9672387" "LeafAnnotation" "Defective F8 accelerates dissociation of the A2 domain" "ReactomePathway" "1" "1" "1" "100" "False" "" "2109" "R-HSA-9672391" "LeafAnnotation" "Defective F8 cleavage by thrombin" "ReactomePathway" "3" "3" "3" "100" "False" "" "2110" "R-HSA-9672393" "LeafAnnotation" "Defective F8 binding to von Willebrand factor" "ReactomePathway" "2" "2" "2" "100" "False" "" "2111" "R-HSA-9672395" "LeafAnnotation" "Defective F8 binding to the cell membrane" "ReactomePathway" "1" "1" "1" "100" "False" "" "2112" "R-HSA-9672397" "LeafAnnotation" "Defective F8 secretion" "ReactomePathway" "1" "1" "1" "100" "False" "" "2113" "R-HSA-173599" "LeafAnnotation" "Formation of the active cofactor, UDP-glucuronate" "ReactomePathway" "2" "2" "3" "67" "False" "" "2114" "R-HSA-3878781" "LeafAnnotation" "Glycogen storage disease type IV (GBE1)" "ReactomePathway" "2" "2" "3" "67" "False" "" "2115" "R-HSA-9636667" "LeafAnnotation" "Manipulation of host energy metabolism" "ReactomePathway" "2" "2" "2" "100" "False" "" "2116" "WP496" "LeafAnnotation" "Steroid biosynthesis" "WikiPathway" "3" "3" "10" "30" "False" "" "2117" "R-HSA-5660668" "LeafAnnotation" "CLEC7A/inflammasome pathway" "ReactomePathway" "3" "3" "6" "50" "False" "" "2118" "WP5256" "LeafAnnotation" "COVID-19 and endothelial cell senescence" "WikiPathway" "2" "2" "4" "50" "False" "" "2119" "R-HSA-71262" "LeafAnnotation" "Carnitine synthesis" "ReactomePathway" "1" "2" "4" "50" "False" "" "2120" "WP4789" "LeafAnnotation" "MED and pseudoachondroplasia genes" "WikiPathway" "2" "2" "6" "33" "False" "" "2121" "R-HSA-5619108" "LeafAnnotation" "Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2122" "R-HSA-1483101" "LeafAnnotation" "Synthesis of PS" "ReactomePathway" "2" "2" "2" "100" "False" "" "2123" "WP2513" "LeafAnnotation" "Nanoparticle triggered regulated necrosis" "WikiPathway" "5" "5" "10" "50" "False" "" "2124" "R-HSA-192814" "LeafAnnotation" "vRNA Synthesis" "ReactomePathway" "1" "1" "1" "100" "False" "" "2125" "WP2249" "LeafAnnotation" "Metastatic brain tumor" "WikiPathway" "2" "2" "5" "40" "False" "" "2126" "R-HSA-5660862" "LeafAnnotation" "Defective SLC7A7 causes lysinuric protein intolerance (LPI)" "ReactomePathway" "1" "1" "2" "50" "False" "" "2127" "R-HSA-5173105" "IntermediateAnnotation" "O-linked glycosylation" "ReactomePathway" "4" "4" "10" "40" "False" "" "2128" "R-HSA-5083628" "LeafAnnotation" "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" "ReactomePathway" "2" "2" "2" "100" "False" "" "2129" "R-HSA-166016" "IntermediateAnnotation" "Toll Like Receptor 4 (TLR4) Cascade" "ReactomePathway" "4" "4" "17" "24" "False" "" "2130" "R-HSA-75109" "LeafAnnotation" "Triglyceride biosynthesis" "ReactomePathway" "2" "4" "14" "29" "False" "" "2131" "R-HSA-111448" "LeafAnnotation" "Activation of NOXA and translocation to mitochondria" "ReactomePathway" "1" "1" "5" "20" "False" "" "2132" "WP2338" "LeafAnnotation" "miRNA biogenesis" "WikiPathway" "3" "3" "5" "60" "False" "" "2133" "R-HSA-2206302" "LeafAnnotation" "MPS I - Hurler syndrome" "ReactomePathway" "1" "1" "1" "100" "False" "" "2134" "R-HSA-70370" "LeafAnnotation" "Galactose catabolism" "ReactomePathway" "3" "3" "4" "75" "False" "" "2135" "R-HSA-5609977" "LeafAnnotation" "Defective GALE causes EDG" "ReactomePathway" "1" "1" "1" "100" "False" "" "2136" "R-HSA-75108" "LeafAnnotation" "Activation, myristolyation of BID and translocation to mitochondria" "ReactomePathway" "2" "2" "4" "50" "False" "" "2137" "R-HSA-111452" "LeafAnnotation" "Activation and oligomerization of BAK protein" "ReactomePathway" "2" "2" "2" "100" "False" "" "2138" "R-HSA-114294" "LeafAnnotation" "Activation, translocation and oligomerization of BAX" "ReactomePathway" "2" "2" "2" "100" "False" "" "2139" "WP1604" "LeafAnnotation" "Codeine and morphine metabolism" "WikiPathway" "2" "2" "14" "14" "False" "" "2140" "WP4211" "LeafAnnotation" "Transcriptional cascade regulating adipogenesis" "WikiPathway" "2" "2" "13" "15" "False" "" "2141" "WP5092" "LeafAnnotation" "Interactions of natural killer cells in pancreatic cancer" "WikiPathway" "4" "4" "18" "22" "False" "" "2142" "R-HSA-6782861" "LeafAnnotation" "Synthesis of wybutosine at G37 of tRNA(Phe)" "ReactomePathway" "2" "2" "6" "33" "False" "" "2143" "R-HSA-8874211" "LeafAnnotation" "CREB3 factors activate genes" "ReactomePathway" "2" "2" "9" "22" "False" "" "2144" "R-HSA-8985801" "LeafAnnotation" "Regulation of cortical dendrite branching" "ReactomePathway" "2" "2" "4" "50" "False" "" "2145" "R-HSA-2206307" "LeafAnnotation" "MPS IIIA - Sanfilippo syndrome A" "ReactomePathway" "1" "1" "1" "100" "False" "" "2146" "R-HSA-446343" "LeafAnnotation" "Localization of the PINCH-ILK-PARVIN complex to focal adhesions" "ReactomePathway" "4" "4" "4" "100" "False" "" "2147" "R-HSA-9674396" "LeafAnnotation" "Imatinib-resistant PDGFR mutants" "ReactomePathway" "1" "1" "1" "100" "False" "" "2148" "R-HSA-9674401" "LeafAnnotation" "Sunitinib-resistant PDGFR mutants" "ReactomePathway" "1" "1" "1" "100" "False" "" "2149" "R-HSA-9674403" "LeafAnnotation" "Regorafenib-resistant PDGFR mutants" "ReactomePathway" "1" "1" "1" "100" "False" "" "2150" "R-HSA-9674404" "LeafAnnotation" "Sorafenib-resistant PDGFR mutants" "ReactomePathway" "1" "1" "1" "100" "False" "" "2151" "R-HSA-9674428" "LeafAnnotation" "PDGFR mutants bind TKIs" "ReactomePathway" "1" "1" "1" "100" "False" "" "2152" "R-HSA-2562578" "LeafAnnotation" "TRIF-mediated programmed cell death" "ReactomePathway" "3" "3" "9" "33" "False" "" "2153" "R-HSA-9013957" "LeafAnnotation" "TLR3-mediated TICAM1-dependent programmed cell death" "ReactomePathway" "2" "2" "6" "33" "False" "" "2154" "R-HSA-5357786" "LeafAnnotation" "TNFR1-induced proapoptotic signaling" "ReactomePathway" "9" "9" "23" "39" "False" "" "2155" "R-HSA-9693928" "LeafAnnotation" "Defective RIPK1-mediated regulated necrosis" "ReactomePathway" "3" "3" "5" "60" "False" "" "2156" "R-HSA-75893" "IntermediateAnnotation" "TNF signaling" "ReactomePathway" "4" "4" "7" "57" "False" "" "2157" "R-HSA-9686347" "LeafAnnotation" "Microbial modulation of RIPK1-mediated regulated necrosis" "ReactomePathway" "1" "1" "4" "25" "False" "" "2158" "R-HSA-9692913" "IntermediateAnnotation" "SARS-CoV-1-mediated effects on programmed cell death" "ReactomePathway" "2" "2" "3" "67" "False" "" "2159" "R-HSA-75158" "LeafAnnotation" "TRAIL signaling" "ReactomePathway" "2" "2" "7" "29" "False" "" "2160" "WP694" "LeafAnnotation" "Arylamine metabolism" "WikiPathway" "1" "1" "6" "17" "False" "" "2161" "R-HSA-156582" "LeafAnnotation" "Acetylation" "ReactomePathway" "1" "1" "1" "100" "False" "" "2162" "WP1971" "LeafAnnotation" "Integrated cancer pathway" "WikiPathway" "2" "3" "13" "23" "False" "" "2163" "R-HSA-9734281" "LeafAnnotation" "Defective HPRT1 disrupts guanine and hypoxanthine salvage" "ReactomePathway" "1" "1" "1" "100" "False" "" "2164" "R-HSA-351202" "IntermediateAnnotation" "Metabolism of polyamines" "ReactomePathway" "2" "2" "4" "50" "False" "" "2165" "R-HSA-8951430" "LeafAnnotation" "RUNX3 regulates WNT signaling" "ReactomePathway" "2" "2" "8" "25" "False" "" "2166" "R-HSA-9636569" "LeafAnnotation" "Suppression of autophagy" "ReactomePathway" "1" "1" "2" "50" "False" "" "2167" "R-HSA-4687000" "LeafAnnotation" "Defective MPDU1 causes CDG-1f" "ReactomePathway" "1" "1" "1" "100" "False" "" "2168" "R-HSA-9692912" "IntermediateAnnotation" "SARS-CoV-1 targets PDZ proteins in cell-cell junction" "ReactomePathway" "1" "1" "1" "100" "False" "" "2169" "R-HSA-549127" "LeafAnnotation" "Organic cation transport" "ReactomePathway" "1" "1" "10" "10" "False" "" "2170" "R-HSA-5619066" "LeafAnnotation" "Defective SLC22A18 causes lung cancer (LNCR) and embryonal rhabdomyosarcoma 1 (RMSE1)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2171" "R-HSA-1483248" "LeafAnnotation" "Synthesis of PIPs at the ER membrane" "ReactomePathway" "4" "4" "5" "80" "False" "" "2172" "R-HSA-8851805" "LeafAnnotation" "MET activates RAS signaling" "ReactomePathway" "5" "5" "8" "62" "False" "" "2173" "R-HSA-9013425" "LeafAnnotation" "RHOT1 GTPase cycle" "ReactomePathway" "3" "3" "5" "60" "False" "" "2174" "R-HSA-8875513" "LeafAnnotation" "MET interacts with TNS proteins" "ReactomePathway" "3" "3" "5" "60" "False" "" "2175" "WP4397" "LeafAnnotation" "Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors" "WikiPathway" "1" "1" "3" "33" "False" "" "2176" "R-HSA-5619048" "LeafAnnotation" "Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2177" "R-HSA-194138" "IntermediateAnnotation" "Signaling by VEGF" "ReactomePathway" "1" "1" "2" "50" "False" "" "2178" "WP2854" "LeafAnnotation" "Gene regulatory network modelling somitogenesis" "WikiPathway" "2" "2" "11" "18" "False" "" "2179" "WP4785" "LeafAnnotation" "Somitogenesis in the context of spondylocostal dysostosis" "WikiPathway" "2" "2" "9" "22" "False" "" "2180" "R-HSA-6806664" "LeafAnnotation" "Metabolism of vitamin K" "ReactomePathway" "2" "2" "3" "67" "False" "" "2181" "R-HSA-9708296" "LeafAnnotation" "tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis" "ReactomePathway" "2" "2" "3" "67" "False" "" "2182" "R-HSA-9648895" "LeafAnnotation" "Response of EIF2AK1 (HRI) to heme deficiency" "ReactomePathway" "5" "5" "15" "33" "False" "" "2183" "R-HSA-156588" "IntermediateAnnotation" "Glucuronidation" "ReactomePathway" "2" "2" "21" "10" "False" "" "2184" "R-HSA-1482798" "LeafAnnotation" "Acyl chain remodeling of CL" "ReactomePathway" "3" "3" "5" "60" "False" "" "2185" "R-HSA-77285" "LeafAnnotation" "Beta oxidation of myristoyl-CoA to lauroyl-CoA" "ReactomePathway" "2" "2" "3" "67" "False" "" "2186" "R-HSA-77305" "LeafAnnotation" "Beta oxidation of palmitoyl-CoA to myristoyl-CoA" "ReactomePathway" "3" "3" "3" "100" "False" "" "2187" "R-HSA-1482801" "LeafAnnotation" "Acyl chain remodelling of PS" "ReactomePathway" "4" "5" "22" "23" "False" "" "2188" "WP4299" "LeafAnnotation" "Lamin A-processing pathway" "WikiPathway" "2" "2" "2" "100" "False" "" "2189" "R-HSA-5619054" "LeafAnnotation" "Defective SLC4A4 causes renal tubular acidosis, proximal, with ocular abnormalities and mental retardation (pRTA-OA)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2190" "R-HSA-5666185" "LeafAnnotation" "RHO GTPases Activate Rhotekin and Rhophilins" "ReactomePathway" "5" "5" "9" "56" "False" "" "2191" "R-HSA-168315" "LeafAnnotation" "Inhibition of Host mRNA Processing and RNA Silencing" "ReactomePathway" "2" "2" "2" "100" "False" "" "2192" "WP3891" "LeafAnnotation" "Benzene metabolism" "WikiPathway" "3" "3" "6" "50" "False" "" "2193" "R-HSA-211945" "IntermediateAnnotation" "Phase I - Functionalization of compounds" "ReactomePathway" "7" "9" "23" "39" "False" "" "2194" "WP1423" "LeafAnnotation" "Ganglio sphingolipid metabolism" "WikiPathway" "2" "2" "13" "15" "False" "" "2195" "R-HSA-425397" "IntermediateAnnotation" "Transport of vitamins, nucleosides, and related molecules" "ReactomePathway" "1" "1" "3" "33" "False" "" "2196" "R-HSA-5619061" "LeafAnnotation" "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2197" "R-HSA-381033" "IntermediateAnnotation" "ATF6 (ATF6-alpha) activates chaperones" "ReactomePathway" "1" "1" "4" "25" "False" "" "2198" "R-HSA-381070" "IntermediateAnnotation" "IRE1alpha activates chaperones" "ReactomePathway" "1" "1" "2" "50" "False" "" "2199" "R-HSA-381042" "IntermediateAnnotation" "PERK regulates gene expression" "ReactomePathway" "5" "5" "6" "83" "False" "" "2200" "R-HSA-1250342" "LeafAnnotation" "PI3K events in ERBB4 signaling" "ReactomePathway" "0" "1" "9" "11" "False" "" "2201" "R-HSA-8851907" "LeafAnnotation" "MET activates PI3K/AKT signaling" "ReactomePathway" "1" "2" "5" "40" "False" "" "2202" "R-HSA-9603381" "LeafAnnotation" "Activated NTRK3 signals through PI3K" "ReactomePathway" "2" "3" "6" "50" "False" "" "2203" "R-HSA-9028335" "LeafAnnotation" "Activated NTRK2 signals through PI3K" "ReactomePathway" "0" "1" "6" "17" "False" "" "2204" "R-HSA-2206292" "LeafAnnotation" "MPS VII - Sly syndrome" "ReactomePathway" "1" "1" "1" "100" "False" "" "2205" "R-HSA-916853" "LeafAnnotation" "Degradation of GABA" "ReactomePathway" "1" "1" "2" "50" "False" "" "2206" "WP4146" "LeafAnnotation" "Macrophage markers" "WikiPathway" "4" "4" "9" "44" "False" "" "2207" "R-HSA-376176" "IntermediateAnnotation" "Signaling by ROBO receptors" "ReactomePathway" "7" "7" "15" "47" "False" "" "2208" "WP3596" "LeafAnnotation" "miR-517 relationship with ARCN1 and USP1" "WikiPathway" "2" "2" "5" "40" "False" "" "2209" "R-HSA-190322" "IntermediateAnnotation" "FGFR4 ligand binding and activation" "ReactomePathway" "1" "2" "11" "18" "False" "" "2210" "R-HSA-5654719" "LeafAnnotation" "SHC-mediated cascade:FGFR4" "ReactomePathway" "3" "4" "15" "27" "False" "" "2211" "R-HSA-1307965" "LeafAnnotation" "betaKlotho-mediated ligand binding" "ReactomePathway" "0" "1" "3" "33" "False" "" "2212" "R-HSA-1839128" "LeafAnnotation" "FGFR4 mutant receptor activation" "ReactomePathway" "0" "1" "1" "100" "False" "" "2213" "R-HSA-5658623" "LeafAnnotation" "FGFRL1 modulation of FGFR1 signaling" "ReactomePathway" "2" "2" "10" "20" "False" "" "2214" "R-HSA-6802953" "LeafAnnotation" "RAS signaling downstream of NF1 loss-of-function variants" "ReactomePathway" "4" "4" "6" "67" "False" "" "2215" "R-HSA-5654687" "IntermediateAnnotation" "Downstream signaling of activated FGFR1" "ReactomePathway" "2" "2" "13" "15" "False" "" "2216" "R-HSA-163680" "LeafAnnotation" "AMPK inhibits chREBP transcriptional activation activity" "ReactomePathway" "2" "4" "8" "50" "False" "" "2217" "R-HSA-2151209" "LeafAnnotation" "Activation of PPARGC1A (PGC-1alpha) by phosphorylation" "ReactomePathway" "3" "5" "10" "50" "False" "" "2218" "WP1991" "LeafAnnotation" "SRF and miRs in smooth muscle differentiation and proliferation" "WikiPathway" "2" "3" "11" "27" "False" "" "2219" "WP3656" "LeafAnnotation" "Interleukin-1 induced activation of NF-kB" "WikiPathway" "5" "5" "9" "56" "False" "" "2220" "R-HSA-111957" "LeafAnnotation" "Cam-PDE 1 activation" "ReactomePathway" "1" "1" "3" "33" "False" "" "2221" "R-HSA-163282" "LeafAnnotation" "Mitochondrial transcription initiation" "ReactomePathway" "2" "2" "3" "67" "False" "" "2222" "WP5181" "LeafAnnotation" "Roles of ceramides in development of insulin resistance" "WikiPathway" "2" "2" "3" "67" "False" "" "2223" "WP5272" "LeafAnnotation" "LDL- influence on CD14 and TLR4" "WikiPathway" "1" "1" "4" "25" "False" "" "2224" "R-HSA-2660826" "LeafAnnotation" "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" "ReactomePathway" "4" "4" "7" "57" "False" "" "2225" "WP5186" "LeafAnnotation" "Vitamin K metabolism and activation of dependent proteins" "WikiPathway" "1" "1" "1" "100" "False" "" "2226" "R-HSA-76009" "IntermediateAnnotation" "Platelet Aggregation (Plug Formation)" "ReactomePathway" "3" "3" "9" "33" "False" "" "2227" "R-HSA-9657688" "LeafAnnotation" "Defective factor XII causes hereditary angioedema" "ReactomePathway" "1" "1" "3" "33" "False" "" "2228" "R-HSA-446199" "LeafAnnotation" "Synthesis of Dolichyl-phosphate" "ReactomePathway" "2" "2" "6" "33" "False" "" "2229" "R-HSA-4755579" "LeafAnnotation" "Defective SRD5A3 causes SRD5A3-CDG, KHRZ" "ReactomePathway" "1" "1" "1" "100" "False" "" "2230" "R-HSA-9640463" "LeafAnnotation" "Wax biosynthesis" "ReactomePathway" "1" "1" "4" "25" "False" "" "2231" "R-HSA-2534343" "LeafAnnotation" "Interaction With Cumulus Cells And The Zona Pellucida" "ReactomePathway" "2" "2" "11" "18" "False" "" "2232" "R-HSA-5653890" "LeafAnnotation" "Lactose synthesis" "ReactomePathway" "2" "2" "3" "67" "False" "" "2233" "R-HSA-4793953" "LeafAnnotation" "Defective B4GALT1 causes CDG-2d" "ReactomePathway" "1" "1" "1" "100" "False" "" "2234" "WP4705" "LeafAnnotation" "Pathways of nucleic acid metabolism and innate immune sensing" "WikiPathway" "1" "1" "4" "25" "False" "" "2235" "R-HSA-3249367" "LeafAnnotation" "STAT6-mediated induction of chemokines" "ReactomePathway" "3" "3" "3" "100" "False" "" "2236" "R-HSA-380612" "LeafAnnotation" "Metabolism of serotonin" "ReactomePathway" "2" "2" "2" "100" "False" "" "2237" "WP5110" "LeafAnnotation" "Familial hyperlipidemia type 3" "WikiPathway" "4" "4" "13" "31" "False" "" "2238" "R-HSA-8866376" "LeafAnnotation" "Reelin signalling pathway" "ReactomePathway" "3" "4" "5" "80" "False" "" "2239" "R-HSA-8964046" "LeafAnnotation" "VLDL clearance" "ReactomePathway" "2" "2" "6" "33" "False" "" "2240" "R-HSA-112303" "LeafAnnotation" "Electric Transmission Across Gap Junctions" "ReactomePathway" "1" "1" "5" "20" "False" "" "2241" "R-HSA-4793954" "LeafAnnotation" "Defective MOGS causes CDG-2b" "ReactomePathway" "1" "1" "1" "100" "False" "" "2242" "WP4863" "LeafAnnotation" "Host-pathogen interaction of human coronaviruses - autophagy" "WikiPathway" "1" "1" "1" "100" "False" "" "2243" "R-HSA-4570571" "LeafAnnotation" "Defective RFT1 causes CDG-1n" "ReactomePathway" "1" "1" "1" "100" "False" "" "2244" "R-HSA-448424" "IntermediateAnnotation" "Interleukin-17 signaling" "ReactomePathway" "1" "1" "8" "12" "False" "" "2245" "WP3875" "LeafAnnotation" "ATR signaling" "WikiPathway" "1" "1" "9" "11" "False" "" "2246" "WP4259" "LeafAnnotation" "Disorders of folate metabolism and transport" "WikiPathway" "1" "1" "1" "100" "False" "" "2247" "R-HSA-4720454" "LeafAnnotation" "Defective ALG9 causes CDG-1l" "ReactomePathway" "1" "1" "1" "100" "False" "" "2248" "R-HSA-9670613" "LeafAnnotation" "Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations" "ReactomePathway" "1" "1" "1" "100" "False" "" "2249" "R-HSA-9670615" "LeafAnnotation" "Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations" "ReactomePathway" "1" "1" "1" "100" "False" "" "2250" "R-HSA-71288" "LeafAnnotation" "Creatine metabolism" "ReactomePathway" "3" "3" "10" "30" "False" "" "2251" "R-HSA-8964208" "LeafAnnotation" "Phenylalanine metabolism" "ReactomePathway" "1" "1" "6" "17" "False" "" "2252" "WP5190" "LeafAnnotation" "Creatine pathway" "WikiPathway" "2" "2" "4" "50" "False" "" "2253" "R-HSA-111471" "IntermediateAnnotation" "Apoptotic factor-mediated response" "ReactomePathway" "1" "1" "2" "50" "False" "" "2254" "R-HSA-9645722" "LeafAnnotation" "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" "ReactomePathway" "1" "1" "2" "50" "False" "" "2255" "R-HSA-5250958" "LeafAnnotation" "Toxicity of botulinum toxin type B (botB)" "ReactomePathway" "2" "2" "3" "67" "False" "" "2256" "R-HSA-425366" "IntermediateAnnotation" "Transport of bile salts and organic acids, metal ions and amine compounds" "ReactomePathway" "3" "3" "11" "27" "False" "" "2257" "WP5095" "LeafAnnotation" "Overview of proinflammatory and profibrotic mediators" "WikiPathway" "3" "3" "120" "2" "False" "" "2258" "R-HSA-380108" "LeafAnnotation" "Chemokine receptors bind chemokines" "ReactomePathway" "1" "1" "57" "2" "False" "" "2259" "R-HSA-2644607" "LeafAnnotation" "Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling" "ReactomePathway" "3" "3" "4" "75" "False" "" "2260" "WP4846" "LeafAnnotation" "SARS-CoV-2 and COVID-19 pathway" "WikiPathway" "1" "1" "3" "33" "False" "" "2261" "R-HSA-77108" "LeafAnnotation" "Utilization of Ketone Bodies" "ReactomePathway" "2" "2" "4" "50" "False" "" "2262" "R-HSA-9734195" "LeafAnnotation" "Defective APRT disrupts adenine salvage" "ReactomePathway" "1" "1" "1" "100" "False" "" "2263" "R-HSA-8963684" "LeafAnnotation" "Tyrosine catabolism" "ReactomePathway" "2" "2" "5" "40" "False" "" "2264" "R-HSA-9759194" "IntermediateAnnotation" "Nuclear events mediated by NFE2L2" "ReactomePathway" "1" "1" "6" "17" "False" "" "2265" "R-HSA-5609974" "LeafAnnotation" "Defective PGM1 causes PGM1-CDG" "ReactomePathway" "1" "1" "1" "100" "False" "" "2266" "R-HSA-9768777" "IntermediateAnnotation" "Regulation of NPAS4 gene transcription" "ReactomePathway" "1" "1" "4" "25" "False" "" "2267" "R-HSA-68884" "IntermediateAnnotation" "Mitotic Telophase/Cytokinesis" "ReactomePathway" "1" "1" "3" "33" "False" "" "2268" "R-HSA-162585" "LeafAnnotation" "Uncoating of the HIV Virion" "ReactomePathway" "1" "1" "1" "100" "False" "" "2269" "R-HSA-162594" "IntermediateAnnotation" "Early Phase of HIV Life Cycle" "ReactomePathway" "2" "2" "3" "67" "False" "" "2270" "R-HSA-164516" "LeafAnnotation" "Minus-strand DNA synthesis" "ReactomePathway" "1" "1" "1" "100" "False" "" "2271" "R-HSA-164525" "LeafAnnotation" "Plus-strand DNA synthesis" "ReactomePathway" "1" "1" "1" "100" "False" "" "2272" "WP1531" "LeafAnnotation" "Vitamin D metabolism" "WikiPathway" "3" "3" "10" "30" "False" "" "2273" "R-HSA-5578996" "LeafAnnotation" "Defective CYP27A1 causes CTX" "ReactomePathway" "1" "1" "1" "100" "False" "" "2274" "R-HSA-187706" "LeafAnnotation" "Signalling to p38 via RIT and RIN" "ReactomePathway" "0" "1" "5" "20" "False" "" "2275" "R-HSA-5619039" "LeafAnnotation" "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2276" "WP5037" "LeafAnnotation" "Riboflavin and CoQ disorders" "WikiPathway" "1" "1" "1" "100" "False" "" "2277" "R-HSA-211981" "IntermediateAnnotation" "Xenobiotics" "ReactomePathway" "1" "1" "22" "5" "False" "" "2278" "R-HSA-211999" "LeafAnnotation" "CYP2E1 reactions" "ReactomePathway" "1" "1" "10" "10" "False" "" "2279" "R-HSA-211958" "LeafAnnotation" "Miscellaneous substrates" "ReactomePathway" "2" "2" "12" "17" "False" "" "2280" "R-HSA-1483213" "LeafAnnotation" "Synthesis of PE" "ReactomePathway" "3" "3" "13" "23" "False" "" "2281" "R-HSA-168316" "IntermediateAnnotation" "Assembly of Viral Components at the Budding Site" "ReactomePathway" "2" "2" "2" "100" "False" "" "2282" "R-HSA-428542" "LeafAnnotation" "Regulation of commissural axon pathfinding by SLIT and ROBO" "ReactomePathway" "2" "2" "9" "22" "False" "" "2283" "R-HSA-8985586" "LeafAnnotation" "SLIT2:ROBO1 increases RHOA activity" "ReactomePathway" "3" "3" "4" "75" "False" "" "2284" "WP4523" "LeafAnnotation" "Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism" "WikiPathway" "1" "1" "14" "7" "False" "" "2285" "R-HSA-6806942" "LeafAnnotation" "MET Receptor Activation" "ReactomePathway" "2" "2" "6" "33" "False" "" "2286" "R-HSA-2393930" "LeafAnnotation" "Phosphate bond hydrolysis by NUDT proteins" "ReactomePathway" "1" "1" "4" "25" "False" "" "2287" "WP3943" "LeafAnnotation" "Robo4 and VEGF signaling pathways crosstalk" "WikiPathway" "3" "3" "6" "50" "False" "" "2288" "R-HSA-9032500" "IntermediateAnnotation" "Activated NTRK2 signals through FYN" "ReactomePathway" "1" "1" "4" "25" "False" "" "2289" "WP5144" "LeafAnnotation" "NRP1-triggered signaling pathways in pancreatic cancer" "WikiPathway" "2" "2" "2" "100" "False" "" "2290" "R-HSA-3772470" "LeafAnnotation" "Negative regulation of TCF-dependent signaling by WNT ligand antagonists" "ReactomePathway" "3" "3" "15" "20" "False" "" "2291" "R-HSA-1234174" "IntermediateAnnotation" "Cellular response to hypoxia" "ReactomePathway" "1" "1" "3" "33" "False" "" "2292" "R-HSA-390918" "IntermediateAnnotation" "Peroxisomal lipid metabolism" "ReactomePathway" "2" "2" "5" "40" "False" "" "2293" "R-HSA-425561" "LeafAnnotation" "Sodium/Calcium exchangers" "ReactomePathway" "2" "2" "10" "20" "False" "" "2294" "R-HSA-2206285" "LeafAnnotation" "MPS VI - Maroteaux-Lamy syndrome" "ReactomePathway" "1" "1" "1" "100" "False" "" "2295" "R-HSA-4793952" "LeafAnnotation" "Defective MGAT2 causes CDG-2a" "ReactomePathway" "1" "1" "1" "100" "False" "" "2296" "R-HSA-2206282" "LeafAnnotation" "MPS IIIB - Sanfilippo syndrome B" "ReactomePathway" "1" "1" "1" "100" "False" "" "2297" "R-HSA-3359475" "LeafAnnotation" "Defective MMAA causes MMA, cblA type" "ReactomePathway" "1" "1" "2" "50" "False" "" "2298" "R-HSA-3359478" "LeafAnnotation" "Defective MUT causes MMAM" "ReactomePathway" "1" "1" "2" "50" "False" "" "2299" "R-HSA-9759218" "LeafAnnotation" "Cobalamin (Cbl) metabolism" "ReactomePathway" "3" "3" "7" "43" "False" "" "2300" "WP1133" "LeafAnnotation" "Androgen receptor signaling pathway" "WikiPathway" "2" "2" "4" "50" "False" "" "2301" "WP3672" "LeafAnnotation" "lncRNA-mediated mechanisms of therapeutic resistance" "WikiPathway" "3" "3" "6" "50" "False" "" "2302" "WP897" "LeafAnnotation" "Androgen receptor signaling pathway" "WikiPathway" "2" "2" "4" "50" "False" "" "2303" "R-HSA-8866911" "LeafAnnotation" "TFAP2 (AP-2) family regulates transcription of cell cycle factors" "ReactomePathway" "1" "1" "5" "20" "False" "" "2304" "R-HSA-8941855" "LeafAnnotation" "RUNX3 regulates CDKN1A transcription" "ReactomePathway" "2" "2" "7" "29" "False" "" "2305" "WP5174" "LeafAnnotation" "Ulcerative colitis signaling" "WikiPathway" "1" "1" "9" "11" "False" "" "2306" "WP5108" "LeafAnnotation" "Familial hyperlipidemia type 1" "WikiPathway" "4" "4" "17" "24" "False" "" "2307" "WP5112" "LeafAnnotation" "Familial hyperlipidemia type 5" "WikiPathway" "4" "4" "14" "29" "False" "" "2308" "WP690" "LeafAnnotation" "Polyol pathway" "WikiPathway" "3" "3" "4" "75" "False" "" "2309" "R-HSA-5652227" "LeafAnnotation" "Fructose biosynthesis" "ReactomePathway" "2" "2" "2" "100" "False" "" "2310" "WP3971" "LeafAnnotation" "OSX and miRNAs in tooth development" "WikiPathway" "4" "4" "15" "27" "False" "" "2311" "R-HSA-9818749" "IntermediateAnnotation" "Regulation of NFE2L2 gene expression" "ReactomePathway" "1" "1" "3" "33" "False" "" "2312" "R-HSA-5083630" "LeafAnnotation" "Defective LFNG causes SCDO3" "ReactomePathway" "3" "3" "5" "60" "False" "" "2313" "R-HSA-6793080" "LeafAnnotation" "rRNA modification in the mitochondrion" "ReactomePathway" "2" "2" "6" "33" "False" "" "2314" "R-HSA-69183" "IntermediateAnnotation" "Processive synthesis on the lagging strand" "ReactomePathway" "2" "2" "10" "20" "False" "" "2315" "R-HSA-1566977" "LeafAnnotation" "Fibronectin matrix formation" "ReactomePathway" "3" "3" "5" "60" "False" "" "2316" "WP229" "LeafAnnotation" "Irinotecan pathway" "WikiPathway" "2" "2" "12" "17" "False" "" "2317" "R-HSA-3359471" "LeafAnnotation" "Defective MMAB causes MMA, cblB type" "ReactomePathway" "1" "1" "1" "100" "False" "" "2318" "R-HSA-6807047" "LeafAnnotation" "Cholesterol biosynthesis via desmosterol" "ReactomePathway" "3" "3" "4" "75" "False" "" "2319" "R-HSA-6807062" "LeafAnnotation" "Cholesterol biosynthesis via lathosterol" "ReactomePathway" "3" "3" "4" "75" "False" "" "2320" "R-HSA-6803544" "LeafAnnotation" "Ion influx/efflux at host-pathogen interface" "ReactomePathway" "1" "1" "4" "25" "False" "" "2321" "R-HSA-5684045" "LeafAnnotation" "Defective ABCD1 causes ALD" "ReactomePathway" "1" "1" "1" "100" "False" "" "2322" "R-HSA-2142816" "LeafAnnotation" "Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE)" "ReactomePathway" "1" "1" "8" "12" "False" "" "2323" "R-HSA-5579011" "LeafAnnotation" "Defective CYP2U1 causes SPG56" "ReactomePathway" "1" "1" "1" "100" "False" "" "2324" "R-HSA-5250982" "LeafAnnotation" "Toxicity of tetanus toxin (tetX)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2325" "R-HSA-5609976" "LeafAnnotation" "Defective GALK1 causes GALCT2" "ReactomePathway" "1" "1" "1" "100" "False" "" "2326" "R-HSA-112126" "LeafAnnotation" "ALKBH3 mediated reversal of alkylation damage" "ReactomePathway" "2" "2" "4" "50" "False" "" "2327" "R-HSA-2033519" "LeafAnnotation" "Activated point mutants of FGFR2" "ReactomePathway" "1" "2" "14" "14" "False" "" "2328" "R-HSA-2023837" "LeafAnnotation" "Signaling by FGFR2 amplification mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2329" "R-HSA-8853333" "LeafAnnotation" "Signaling by FGFR2 fusions" "ReactomePathway" "0" "1" "1" "100" "False" "" "2330" "R-HSA-8869496" "LeafAnnotation" "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" "ReactomePathway" "3" "3" "5" "60" "False" "" "2331" "R-HSA-4411364" "LeafAnnotation" "Binding of TCF/LEF:CTNNB1 to target gene promoters" "ReactomePathway" "1" "1" "7" "14" "False" "" "2332" "R-HSA-1296052" "LeafAnnotation" "Ca2+ activated K+ channels" "ReactomePathway" "1" "1" "9" "11" "False" "" "2333" "R-HSA-9667769" "LeafAnnotation" "Acetylcholine inhibits contraction of outer hair cells" "ReactomePathway" "1" "1" "5" "20" "False" "" "2334" "R-HSA-139910" "LeafAnnotation" "Activation of BMF and translocation to mitochondria" "ReactomePathway" "1" "1" "3" "33" "False" "" "2335" "R-HSA-112314" "IntermediateAnnotation" "Neurotransmitter receptors and postsynaptic signal transmission" "ReactomePathway" "0" "1" "10" "10" "False" "" "2336" "R-HSA-9022535" "LeafAnnotation" "Loss of phosphorylation of MECP2 at T308" "ReactomePathway" "1" "1" "2" "50" "False" "" "2337" "R-HSA-4085023" "LeafAnnotation" "Defective GFPT1 causes CMSTA1" "ReactomePathway" "1" "1" "1" "100" "False" "" "2338" "R-HSA-1236973" "LeafAnnotation" "Cross-presentation of particulate exogenous antigens (phagosomes)" "ReactomePathway" "2" "2" "8" "25" "False" "" "2339" "R-HSA-75102" "LeafAnnotation" "C6 deamination of adenosine" "ReactomePathway" "1" "1" "2" "50" "False" "" "2340" "R-HSA-77042" "LeafAnnotation" "Formation of editosomes by ADAR proteins" "ReactomePathway" "1" "1" "2" "50" "False" "" "2341" "R-HSA-9694301" "LeafAnnotation" "Maturation of replicase proteins" "ReactomePathway" "1" "1" "1" "100" "False" "" "2342" "R-HSA-5619083" "LeafAnnotation" "Defective SLC35A3 causes arthrogryposis, mental retardation, and seizures (AMRS)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2343" "R-HSA-444473" "LeafAnnotation" "Formyl peptide receptors bind formyl peptides and many other ligands" "ReactomePathway" "3" "3" "8" "38" "False" "" "2344" "WP5179" "LeafAnnotation" "Biosynthesis and turnover of 1-deoxy-sphingoid bases" "WikiPathway" "5" "5" "8" "62" "False" "" "2345" "R-HSA-5578997" "LeafAnnotation" "Defective AHCY causes HMAHCHD" "ReactomePathway" "1" "1" "1" "100" "False" "" "2346" "WP3594" "LeafAnnotation" "Circadian rhythm genes" "WikiPathway" "1" "1" "2" "50" "False" "" "2347" "R-HSA-9735763" "LeafAnnotation" "Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine" "ReactomePathway" "1" "1" "1" "100" "False" "" "2348" "R-HSA-2142712" "LeafAnnotation" "Synthesis of 12-eicosatetraenoic acid derivatives" "ReactomePathway" "3" "3" "7" "43" "False" "" "2349" "R-HSA-5579006" "LeafAnnotation" "Defective GSS causes GSS deficiency" "ReactomePathway" "1" "1" "1" "100" "False" "" "2350" "R-HSA-166166" "IntermediateAnnotation" "MyD88-independent TLR4 cascade" "ReactomePathway" "1" "1" "5" "20" "False" "" "2351" "R-HSA-168179" "IntermediateAnnotation" "Toll Like Receptor TLR1:TLR2 Cascade" "ReactomePathway" "1" "1" "5" "20" "False" "" "2352" "R-HSA-168188" "IntermediateAnnotation" "Toll Like Receptor TLR6:TLR2 Cascade" "ReactomePathway" "1" "1" "4" "25" "False" "" "2353" "R-HSA-166020" "LeafAnnotation" "Transfer of LPS from LBP carrier to CD14" "ReactomePathway" "1" "1" "2" "50" "False" "" "2354" "R-HSA-9692914" "IntermediateAnnotation" "SARS-CoV-1-host interactions" "ReactomePathway" "2" "2" "2" "100" "False" "" "2355" "WP108" "LeafAnnotation" "Selenium metabolism / selenoproteins" "WikiPathway" "1" "1" "1" "100" "False" "" "2356" "WP3655" "LeafAnnotation" "Hypothetical craniofacial development pathway" "WikiPathway" "2" "2" "7" "29" "False" "" "2357" "WP5199" "LeafAnnotation" "PtdIns(4,5)P2 in cytokinesis pathway" "WikiPathway" "1" "1" "1" "100" "False" "" "2358" "R-HSA-168275" "LeafAnnotation" "Entry of Influenza Virion into Host Cell via Endocytosis" "ReactomePathway" "2" "2" "2" "100" "False" "" "2359" "WP5044" "LeafAnnotation" "Kynurenine pathway and links to cell senescence" "WikiPathway" "1" "1" "3" "33" "False" "" "2360" "R-HSA-9734735" "LeafAnnotation" "Defective ADA disrupts (deoxy)adenosine deamination" "ReactomePathway" "1" "1" "1" "100" "False" "" "2361" "R-HSA-70688" "LeafAnnotation" "Proline catabolism" "ReactomePathway" "1" "1" "3" "33" "False" "" "2362" "R-HSA-5676594" "LeafAnnotation" "TNF receptor superfamily (TNFSF) members mediating non-canonical NF-kB pathway" "ReactomePathway" "1" "1" "16" "6" "False" "" "2363" "R-HSA-4720475" "LeafAnnotation" "Defective ALG3 causes CDG-1d" "ReactomePathway" "1" "1" "1" "100" "False" "" "2364" "R-HSA-72200" "IntermediateAnnotation" "mRNA Editing: C to U Conversion" "ReactomePathway" "1" "1" "8" "12" "False" "" "2365" "R-HSA-75094" "LeafAnnotation" "Formation of the Editosome" "ReactomePathway" "1" "1" "8" "12" "False" "" "2366" "WP2645" "LeafAnnotation" "Heroin metabolism" "WikiPathway" "1" "1" "3" "33" "False" "" "2367" "R-HSA-5619043" "LeafAnnotation" "Defective SLC2A1 causes GLUT1 deficiency syndrome 1 (GLUT1DS1)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2368" "R-HSA-5657560" "LeafAnnotation" "Hereditary fructose intolerance" "ReactomePathway" "1" "1" "1" "100" "False" "" "2369" "R-HSA-203754" "LeafAnnotation" "NOSIP mediated eNOS trafficking" "ReactomePathway" "1" "1" "2" "50" "False" "" "2370" "R-HSA-1222449" "LeafAnnotation" "Mtb iron assimilation by chelation" "ReactomePathway" "1" "1" "1" "100" "False" "" "2371" "R-HSA-5654688" "LeafAnnotation" "SHC-mediated cascade:FGFR1" "ReactomePathway" "3" "3" "13" "23" "False" "" "2372" "R-HSA-5654699" "LeafAnnotation" "SHC-mediated cascade:FGFR2" "ReactomePathway" "3" "3" "16" "19" "False" "" "2373" "R-HSA-5654704" "LeafAnnotation" "SHC-mediated cascade:FGFR3" "ReactomePathway" "3" "3" "11" "27" "False" "" "2374" "R-HSA-1169092" "LeafAnnotation" "Activation of RAS in B cells" "ReactomePathway" "2" "2" "4" "50" "False" "" "2375" "R-HSA-112412" "LeafAnnotation" "SOS-mediated signalling" "ReactomePathway" "3" "3" "5" "60" "False" "" "2376" "R-HSA-9026519" "LeafAnnotation" "Activated NTRK2 signals through RAS" "ReactomePathway" "2" "2" "6" "33" "False" "" "2377" "R-HSA-9034864" "LeafAnnotation" "Activated NTRK3 signals through RAS" "ReactomePathway" "2" "2" "5" "40" "False" "" "2378" "R-HSA-9682706" "LeafAnnotation" "Replication of the SARS-CoV-1 genome" "ReactomePathway" "2" "2" "4" "50" "False" "" "2379" "R-HSA-9694686" "LeafAnnotation" "Replication of the SARS-CoV-2 genome" "ReactomePathway" "2" "2" "4" "50" "False" "" "2380" "R-HSA-844455" "LeafAnnotation" "The NLRP1 inflammasome" "ReactomePathway" "1" "1" "3" "33" "False" "" "2381" "R-HSA-8952158" "LeafAnnotation" "RUNX3 regulates BCL2L11 (BIM) transcription" "ReactomePathway" "1" "1" "5" "20" "False" "" "2382" "WP4236" "LeafAnnotation" "Krebs cycle disorders" "WikiPathway" "2" "2" "2" "100" "False" "" "2383" "R-HSA-190370" "LeafAnnotation" "FGFR1b ligand binding and activation" "ReactomePathway" "1" "1" "5" "20" "False" "" "2384" "R-HSA-190377" "LeafAnnotation" "FGFR2b ligand binding and activation" "ReactomePathway" "1" "1" "9" "11" "False" "" "2385" "R-HSA-190372" "LeafAnnotation" "FGFR3c ligand binding and activation" "ReactomePathway" "1" "1" "9" "11" "False" "" "2386" "R-HSA-190375" "LeafAnnotation" "FGFR2c ligand binding and activation" "ReactomePathway" "1" "1" "9" "11" "False" "" "2387" "R-HSA-190373" "LeafAnnotation" "FGFR1c ligand binding and activation" "ReactomePathway" "1" "1" "8" "12" "False" "" "2388" "R-HSA-6791055" "LeafAnnotation" "TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P" "ReactomePathway" "1" "1" "1" "100" "False" "" "2389" "R-HSA-6791462" "LeafAnnotation" "TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P" "ReactomePathway" "1" "1" "1" "100" "False" "" "2390" "R-HSA-4793950" "LeafAnnotation" "Defective MAN1B1 causes MRT15" "ReactomePathway" "1" "1" "1" "100" "False" "" "2391" "R-HSA-9032759" "LeafAnnotation" "NTRK2 activates RAC1" "ReactomePathway" "1" "1" "4" "25" "False" "" "2392" "R-HSA-9032845" "LeafAnnotation" "Activated NTRK2 signals through CDK5" "ReactomePathway" "2" "2" "6" "33" "False" "" "2393" "WP4271" "LeafAnnotation" "Vitamin B12 disorders" "WikiPathway" "1" "1" "1" "100" "False" "" "2394" "R-HSA-3359467" "LeafAnnotation" "Defective MTRR causes HMAE" "ReactomePathway" "1" "1" "2" "50" "False" "" "2395" "R-HSA-3359469" "LeafAnnotation" "Defective MTR causes HMAG" "ReactomePathway" "1" "1" "2" "50" "False" "" "2396" "R-HSA-5576890" "LeafAnnotation" "Phase 3 - rapid repolarisation" "ReactomePathway" "1" "1" "9" "11" "False" "" "2397" "R-HSA-9661070" "LeafAnnotation" "Defective translocation of RB1 mutants to the nucleus" "ReactomePathway" "1" "1" "1" "100" "False" "" "2398" "R-HSA-975574" "LeafAnnotation" "Reactions specific to the hybrid N-glycan synthesis pathway" "ReactomePathway" "1" "1" "1" "100" "False" "" "2399" "R-HSA-8864260" "IntermediateAnnotation" "Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors" "ReactomePathway" "2" "2" "3" "67" "False" "" "2400" "R-HSA-1296061" "LeafAnnotation" "HCN channels" "ReactomePathway" "1" "1" "4" "25" "False" "" "2401" "WP4873" "LeafAnnotation" "Peroxiredoxin 2 induced ovarian failure" "WikiPathway" "2" "2" "6" "33" "False" "" "2402" "R-HSA-211736" "LeafAnnotation" "Stimulation of the cell death response by PAK-2p34" "ReactomePathway" "2" "2" "2" "100" "False" "" "2403" "R-HSA-5619070" "LeafAnnotation" "Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)" "ReactomePathway" "2" "2" "2" "100" "False" "" "2404" "R-HSA-5339700" "LeafAnnotation" "Signaling by TCF7L2 mutants" "ReactomePathway" "2" "2" "3" "67" "False" "" "2405" "R-HSA-442660" "LeafAnnotation" "Na+/Cl- dependent neurotransmitter transporters" "ReactomePathway" "1" "1" "19" "5" "False" "" "2406" "R-HSA-3248023" "LeafAnnotation" "Regulation by TREX1" "ReactomePathway" "1" "1" "1" "100" "False" "" "2407" "R-HSA-3560796" "LeafAnnotation" "Defective PAPSS2 causes SEMD-PA" "ReactomePathway" "1" "1" "1" "100" "False" "" "2408" "R-HSA-2142688" "LeafAnnotation" "Synthesis of 5-eicosatetraenoic acids" "ReactomePathway" "3" "3" "9" "33" "False" "" "2409" "R-HSA-162599" "IntermediateAnnotation" "Late Phase of HIV Life Cycle" "ReactomePathway" "1" "1" "1" "100" "False" "" "2410" "R-HSA-156711" "LeafAnnotation" "Polo-like kinase mediated events" "ReactomePathway" "2" "2" "16" "12" "False" "" "2411" "R-HSA-429593" "LeafAnnotation" "Inositol transporters" "ReactomePathway" "1" "1" "2" "50" "False" "" "2412" "R-HSA-74713" "LeafAnnotation" "IRS activation" "ReactomePathway" "1" "1" "5" "20" "False" "" "2413" "R-HSA-5633231" "LeafAnnotation" "Defective ALG14 causes ALG14-CMS" "ReactomePathway" "1" "1" "2" "50" "False" "" "2414" "R-HSA-5083629" "LeafAnnotation" "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" "ReactomePathway" "2" "2" "3" "67" "False" "" "2415" "R-HSA-5083633" "LeafAnnotation" "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" "ReactomePathway" "2" "2" "3" "67" "False" "" "2416" "R-HSA-5619035" "LeafAnnotation" "Defective SLC17A5 causes Salla disease (SD) and ISSD" "ReactomePathway" "1" "1" "1" "100" "False" "" "2417" "WP501" "LeafAnnotation" "GPCRs, class C metabotropic glutamate, pheromone" "WikiPathway" "2" "2" "15" "13" "False" "" "2418" "R-HSA-111446" "LeafAnnotation" "Activation of BIM and translocation to mitochondria" "ReactomePathway" "1" "1" "3" "33" "False" "" "2419" "WP2846" "LeafAnnotation" "PCSK9-mediated LDL receptor degradation" "WikiPathway" "1" "1" "2" "50" "False" "" "2420" "WP3408" "LeafAnnotation" "Evolocumab mechanism to reduce LDL cholesterol" "WikiPathway" "1" "1" "2" "50" "False" "" "2421" "WP3601" "LeafAnnotation" "Lipid particles composition" "WikiPathway" "1" "1" "4" "25" "False" "" "2422" "R-HSA-5662853" "LeafAnnotation" "Essential pentosuria" "ReactomePathway" "1" "1" "1" "100" "False" "" "2423" "R-HSA-169131" "LeafAnnotation" "Inhibition of PKR" "ReactomePathway" "1" "1" "1" "100" "False" "" "2424" "R-HSA-2161517" "LeafAnnotation" "Abacavir transmembrane transport" "ReactomePathway" "1" "1" "5" "20" "False" "" "2425" "R-HSA-9754706" "LeafAnnotation" "Atorvastatin ADME" "ReactomePathway" "1" "1" "8" "12" "False" "" "2426" "R-HSA-9018681" "LeafAnnotation" "Biosynthesis of protectins" "ReactomePathway" "1" "1" "4" "25" "False" "" "2427" "R-HSA-9018676" "LeafAnnotation" "Biosynthesis of D-series resolvins" "ReactomePathway" "1" "1" "3" "33" "False" "" "2428" "R-HSA-9018896" "LeafAnnotation" "Biosynthesis of E-series 18(S)-resolvins" "ReactomePathway" "1" "1" "4" "25" "False" "" "2429" "R-HSA-9020265" "LeafAnnotation" "Biosynthesis of aspirin-triggered D-series resolvins" "ReactomePathway" "1" "1" "2" "50" "False" "" "2430" "R-HSA-9023661" "LeafAnnotation" "Biosynthesis of E-series 18(R)-resolvins" "ReactomePathway" "1" "1" "3" "33" "False" "" "2431" "R-HSA-9702509" "LeafAnnotation" "FLT3 mutants bind TKIs" "ReactomePathway" "0" "1" "1" "100" "False" "" "2432" "R-HSA-9702569" "LeafAnnotation" "KW2449-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2433" "R-HSA-9702577" "LeafAnnotation" "semaxanib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2434" "R-HSA-9702581" "LeafAnnotation" "crenolanib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2435" "R-HSA-9702590" "LeafAnnotation" "gilteritinib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2436" "R-HSA-9702596" "LeafAnnotation" "lestaurtinib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2437" "R-HSA-9702600" "LeafAnnotation" "midostaurin-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2438" "R-HSA-9702605" "LeafAnnotation" "pexidartinib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2439" "R-HSA-9702614" "LeafAnnotation" "ponatinib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2440" "R-HSA-9702620" "LeafAnnotation" "quizartinib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2441" "R-HSA-9702624" "LeafAnnotation" "sorafenib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2442" "R-HSA-9702632" "LeafAnnotation" "sunitinib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2443" "R-HSA-9702636" "LeafAnnotation" "tandutinib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2444" "R-HSA-9702998" "LeafAnnotation" "linifanib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2445" "R-HSA-9703009" "LeafAnnotation" "tamatinib-resistant FLT3 mutants" "ReactomePathway" "0" "1" "1" "100" "False" "" "2446" "R-HSA-964975" "LeafAnnotation" "Vitamins B6 activation to pyridoxal phosphate" "ReactomePathway" "2" "2" "3" "67" "False" "" "2447" "R-HSA-2187335" "LeafAnnotation" "The retinoid cycle in cones (daylight vision)" "ReactomePathway" "1" "1" "6" "17" "False" "" "2448" "R-HSA-5362798" "LeafAnnotation" "Release of Hh-Np from the secreting cell" "ReactomePathway" "1" "1" "8" "12" "False" "" "2449" "R-HSA-9734091" "LeafAnnotation" "Drug-mediated inhibition of MET activation" "ReactomePathway" "1" "1" "2" "50" "False" "" "2450" "R-HSA-879518" "LeafAnnotation" "Transport of organic anions" "ReactomePathway" "1" "1" "10" "10" "False" "" "2451" "WP125" "LeafAnnotation" "Biogenic amine synthesis" "WikiPathway" "1" "1" "6" "17" "False" "" "2452" "WP4220" "LeafAnnotation" "Neurotransmitter disorders" "WikiPathway" "1" "1" "2" "50" "False" "" "2453" "R-HSA-379401" "IntermediateAnnotation" "Dopamine clearance from the synaptic cleft" "ReactomePathway" "1" "1" "2" "50" "False" "" "2454" "R-HSA-5579012" "LeafAnnotation" "Defective MAOA causes BRUNS" "ReactomePathway" "1" "1" "1" "100" "False" "" "2455" "R-HSA-196819" "LeafAnnotation" "Vitamin B1 (thiamin) metabolism" "ReactomePathway" "1" "1" "5" "20" "False" "" "2456" "R-HSA-8849175" "LeafAnnotation" "Threonine catabolism" "ReactomePathway" "2" "2" "5" "40" "False" "" "2457" "R-HSA-420499" "LeafAnnotation" "Class C/3 (Metabotropic glutamate/pheromone receptors)" "ReactomePathway" "1" "1" "40" "2" "False" "" "2458" "R-HSA-977444" "IntermediateAnnotation" "GABA B receptor activation" "ReactomePathway" "1" "1" "2" "50" "False" "" "2459" "R-HSA-5221030" "LeafAnnotation" "TET1,2,3 and TDG demethylate DNA" "ReactomePathway" "1" "1" "4" "25" "False" "" "2460" "R-HSA-4549349" "LeafAnnotation" "Defective ALG2 causes CDG-1i" "ReactomePathway" "1" "1" "1" "100" "False" "" "2461" "R-HSA-427652" "IntermediateAnnotation" "Sodium-coupled phosphate cotransporters" "ReactomePathway" "2" "2" "2" "100" "False" "" "2462" "R-HSA-5619111" "LeafAnnotation" "Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1)" "ReactomePathway" "1" "1" "1" "100" "False" "" "2463" "WP4756" "LeafAnnotation" "Renin-angiotensin-aldosterone system (RAAS)" "WikiPathway" "1" "1" "7" "14" "False" "" "2464" "WP4818" "LeafAnnotation" "Conversion of angiotensinogen to angiotensin II" "WikiPathway" "1" "1" "1" "100" "False" "" "2465" "R-HSA-5083627" "LeafAnnotation" "Defective LARGE causes MDDGA6 and MDDGB6" "ReactomePathway" "1" "1" "2" "50" "False" "" "2466" "R-HSA-3858516" "LeafAnnotation" "Glycogen storage disease type 0 (liver GYS2)" "ReactomePathway" "1" "1" "2" "50" "False" "" "2467" "R-HSA-9034015" "IntermediateAnnotation" "Signaling by NTRK3 (TRKC)" "ReactomePathway" "1" "1" "4" "25" "False" "" "2468" "R-HSA-4085011" "LeafAnnotation" "Defective GNE causes sialuria, NK and IBM2" "ReactomePathway" "1" "1" "1" "100" "False" "" "2469" "R-HSA-1855231" "LeafAnnotation" "Synthesis of IPs in the ER lumen" "ReactomePathway" "1" "1" "1" "100"