"Checked"	"Protein FDR Confidence: MS Amanda 2.0"	"Protein FDR Confidence: Sequest HT"	"Master"	"Accession"	"Description"	"Exp. q-value: MS Amanda 2.0"	"Exp. q-value: Sequest HT"	"Coverage [%]"	"# Peptides"	"# PSMs"	"# Unique Peptides"	"# AAs"	"MW [kDa]"	"calc. pI"	"Score MS Amanda 2.0: MS Amanda 2.0"	"Score Sequest HT: Sequest HT"	"# Peptides (by Search Engine): MS Amanda 2.0"	"# Peptides (by Search Engine): Sequest HT"	"Biological Process"	"Cellular Component"	"Molecular Function"	"Pfam IDs"	"Entrez Gene ID"	"Ensembl Gene ID"	"Gene Symbol"	"Gene ID"	"Reactome Pathways"	"WikiPathways"	"# Protein Pathway Groups"	"# Razor Peptides"	"Abundances (Grouped): 126"	"Abundances (Grouped): 127N"	"Abundances (Grouped): 127C"	"Abundances (Grouped): 128N"	"Abundances (Grouped): 128C"	"Abundances (Grouped): 129N"	"Abundances (Grouped): 129C"	"Abundances (Grouped): 130N"	"Abundances (Grouped): 130C"	"Abundances (Grouped): 131N"	"Abundances (Grouped): 131C"	"Abundances (Grouped) CV [%]: 126"	"Abundances (Grouped) CV [%]: 127N"	"Abundances (Grouped) CV [%]: 127C"	"Abundances (Grouped) CV [%]: 128N"	"Abundances (Grouped) CV [%]: 128C"	"Abundances (Grouped) CV [%]: 129N"	"Abundances (Grouped) CV [%]: 129C"	"Abundances (Grouped) CV [%]: 130N"	"Abundances (Grouped) CV [%]: 130C"	"Abundances (Grouped) CV [%]: 131N"	"Abundances (Grouped) CV [%]: 131C"	"Found in Sample: F5: 126, Sample"	"Found in Sample: F5: 127N, Sample"	"Found in Sample: F5: 127C, Sample"	"Found in Sample: F5: 128N, Sample"	"Found in Sample: F5: 128C, Sample"	"Found in Sample: F5: 129N, Sample"	"Found in Sample: F5: 129C, Sample"	"Found in Sample: F5: 130N, Sample"	"Found in Sample: F5: 130C, Sample"	"Found in Sample: F5: 131N, Sample"	"Found in Sample: F5: 131C, Sample"	"# Protein Groups"	"Modifications"
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13813"	"Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3"	"0.000"	""	"69"	"172"	"492"	"172"	"2472"	"284.4"	"5.35"	"84789.92"	"1071.12"	"136"	"159"	"cell organization and biogenesis"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00435, Pf08726, Pf13499"	"6709"	"ENSG00000197694"	"SPTAN1"	"hsa:6709; Q13186; Q13813; Q15324; Q16606; Q59EF1; Q5VXV5; Q5VXV6; Q7Z6M5; Q9P0V0"	"Neutrophil degranulation; RHOV GTPase cycle; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOU GTPase cycle; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins; Caspase-mediated cleavage of cytoskeletal proteins"	"Fas ligand pathway and stress induction of heat shock proteins"	"12"	"0"	"2198.6"	"1550.4"	"2685.4"	"2194.9"	"2415.4"	"2359.0"	"4789.2"	"527.8"	"138790.3"	"138864.0"	"207726.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01082"	"Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2"	"0.000"	""	"57"	"134"	"377"	"119"	"2364"	"274.4"	"5.57"	"73353.15"	"777.23"	"112"	"123"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00435"	"6711"	"ENSG00000115306"	"SPTBN1"	"B2RP63; hsa:6711; O60837; Q01082; Q16057; Q53R99; Q59ER3; Q8IX99"	"RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Signaling by FLT3 fusion proteins; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; Interaction between L1 and Ankyrins"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"16"	"1548.0"	"1076.6"	"1921.2"	"1608.5"	"1748.8"	"1667.9"	"3198.5"	"374.2"	"89952.0"	"94686.7"	"148470.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXH0"	"Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3"	"0.000"	""	"20"	"116"	"231"	"114"	"6885"	"795.9"	"5.36"	"40828.15"	"495.89"	"91"	"111"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23224"	"ENSG00000054654"	"SYNE2"	"B4DND7; B4DPR6; hsa:23224; I6XXQ5; Q540G1; Q86YP9; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5; Q8WXH0; Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1"	"Meiotic synapsis"	"Ovarian infertility; Rett syndrome causing genes; Envelope proteins and their potential roles in EDMD physiopathology"	"4"	"2"	"1004.2"	"743.0"	"1266.6"	"1097.3"	"1121.5"	"1190.8"	"2366.3"	"142.8"	"48455.4"	"47932.6"	"88826.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20700"	"Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2"	"0.000"	""	"70"	"55"	"160"	"50"	"586"	"66.4"	"5.16"	"25839.70"	"356.95"	"45"	"52"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf00932"	"4001"	"ENSG00000113368"	"LMNB1"	"B2R6J6; hsa:4001; P20700; Q3SYN7; Q96EI6"	"RHOD GTPase cycle; RHOF GTPase cycle; Meiotic synapsis; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; Breakdown of the nuclear lamina; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"Fas ligand pathway and stress induction of heat shock proteins; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	"14"	"5"	"3309.7"	"2036.7"	"2330.9"	"2200.0"	"2540.1"	"2309.4"	"4937.5"	"149.0"	"34400.5"	"34207.5"	"52880.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14683"	"Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2"	"0.000"	""	"52"	"73"	"150"	"72"	"1233"	"143.1"	"7.64"	"23475.83"	"303.52"	"50"	"66"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"8243"	"ENSG00000072501"	"SMC1A"	"hsa:8243; O14995; Q14683; Q16351; Q2M228"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Estrogen-dependent gene expression; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; mRNA processing; Regulation of sister chromatid separation at the metaphase-anaphase transition; Rett syndrome causing genes; CAMKK2 pathway; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation; DNA damage response"	"22"	"0"	"2305.9"	"1810.8"	"2443.6"	"2239.9"	"2133.9"	"2281.7"	"4032.7"	"71.0"	"30853.1"	"31351.2"	"72541.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15020"	"Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3"	"0.000"	""	"30"	"68"	"148"	"55"	"2390"	"271.2"	"6.11"	"28310.20"	"298.78"	"59"	"64"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf15410"	"6712"	"ENSG00000173898"	"SPTBN2"	"hsa:6712; O14872; O14873; O15020"	"MHC class II antigen presentation; COPI-mediated anterograde transport; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins"	""	"5"	"0"	"659.5"	"462.7"	"763.9"	"673.4"	"756.0"	"760.3"	"1259.6"	"47.0"	"24588.1"	"25004.6"	"48264.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13639"	"Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4"	"0.000"	""	"54"	"50"	"139"	"49"	"858"	"95.3"	"6.83"	"26429.87"	"287.50"	"40"	"44"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"1938"	"ENSG00000167658"	"EEF2"	"A0A384N6H1; B2RMP5; D6W618; hsa:1938; P13639; Q58J86"	"Neutrophil degranulation; Protein methylation; Uptake and function of diphtheria toxin; Peptide chain elongation; Synthesis of diphthamide-EEF2"	"Translation factors; AMP-activated protein kinase signaling; Brain-derived neurotrophic factor (BDNF) signaling pathway; IL-18 signaling pathway"	"9"	"1"	"739.1"	"552.1"	"774.2"	"730.4"	"747.6"	"722.2"	"1443.7"	"96.5"	"34351.3"	"34215.1"	"59897.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQE7"	"Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2"	"0.000"	""	"49"	"61"	"135"	"61"	"1217"	"141.5"	"7.18"	"23674.92"	"277.14"	"48"	"55"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"9126"	"ENSG00000108055"	"SMC3"	"A8K156; hsa:9126; O60464; Q5T482; Q9UQE7"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"15"	"0"	"1681.8"	"1349.0"	"1706.2"	"1602.9"	"1593.9"	"1689.0"	"3155.0"	"146.5"	"28452.3"	"29743.5"	"66738.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22626"	"Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2"	"0.000"	""	"74"	"28"	"118"	"25"	"353"	"37.4"	"8.95"	"18775.36"	"273.75"	"22"	"26"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3181"	"ENSG00000122566"	"HNRNPA2B1"	"A0A024RA27; A0A024RA61; A8K064; hsa:3181; P22626; P22627; Q9UC98; Q9UDJ2"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"4"	"3"	"5411.7"	"4768.9"	"5326.9"	"5210.7"	"4999.7"	"5032.7"	"11942.1"	"41.3"	"21016.6"	"21133.2"	"31463.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08670"	"Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4"	"0.000"	""	"67"	"39"	"128"	"38"	"466"	"53.6"	"5.12"	"26133.54"	"245.35"	"34"	"37"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf04732"	"7431"	"ENSG00000026025"	"VIM"	"B0YJC2; D3DRU4; hsa:7431; P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3"	"Aggrephagy; Interleukin-4 and Interleukin-13 signaling; Chaperone Mediated Autophagy; Late endosomal microautophagy; Striated Muscle Contraction; RHOBTB1 GTPase cycle; Caspase-mediated cleavage of cytoskeletal proteins"	"Allograft rejection; Spinal cord injury; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Puberty (Stage 2 of 4); Apoptosis-related network due to altered Notch3 in ovarian cancer; Striated muscle contraction pathway; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Ciliary landscape; Burn wound healing; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; A network map of Macrophage-stimulating protein (MSP) signaling; T-cell receptor signaling pathway"	"21"	"1"	"2472.3"	"1680.0"	"2077.0"	"1824.0"	"1643.7"	"1992.2"	"4040.4"	"50.8"	"21190.6"	"20356.4"	"36648.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09666"	"Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2"	"0.000"	""	"25"	"51"	"91"	"51"	"5890"	"628.7"	"6.15"	"13910.48"	"223.74"	"30"	"51"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"79026"	"ENSG00000124942"	"AHNAK"	"A1A586; hsa:79026; Q09666"	""	""	"0"	"0"	"427.7"	"267.8"	"478.7"	"426.0"	"425.1"	"444.8"	"896.2"	"43.9"	"14717.2"	"14264.3"	"33541.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12270"	"Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3"	"0.000"	""	"25"	"54"	"110"	"53"	"2363"	"267.1"	"5.02"	"22744.30"	"222.31"	"48"	"48"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07926"	"7175"	"ENSG00000047410"	"TPR"	"hsa:7175; P12270; Q15624; Q15655; Q5SWY0; Q99968"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; Signaling by ALK fusions and activated point mutants; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"29"	"1"	"2099.2"	"1495.8"	"2079.0"	"1820.7"	"1754.8"	"1949.9"	"3701.6"	"40.9"	"25106.2"	"24578.7"	"48669.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02545"	"Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1"	"0.000"	""	"49"	"41"	"112"	"40"	"664"	"74.1"	"7.02"	"20427.02"	"210.08"	"38"	"40"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"4000"	"ENSG00000160789"	"LMNA"	"B4DI32; D3DVB0; D6RAQ3; E7EUI9; hsa:4000; P02545; P02546; Q5I6Y4; Q5I6Y6; Q5TCJ2; Q5TCJ3; Q6UYC3; Q969I8; Q96JA2"	"Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes"	"Arrhythmogenic right ventricular cardiomyopathy; Adipogenesis; Fas ligand pathway and stress induction of heat shock proteins; Lamin A-processing pathway; Nephrotic syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome; Primary ovarian insufficiency"	"13"	"0"	"1446.6"	"1013.1"	"1391.6"	"1196.6"	"1246.2"	"1407.2"	"4147.2"	"55.7"	"28814.7"	"28507.5"	"43147.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08133"	"Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3"	"0.000"	""	"52"	"36"	"98"	"36"	"673"	"75.8"	"5.60"	"15333.26"	"201.16"	"24"	"36"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;cytoskeletal activity;other molecular function"	"Pf00191"	"309"	"ENSG00000197043"	"ANXA6"	"B7Z8A7; D3DQH4; E9PGK1; hsa:309; P08133; Q6ZT79"	"Smooth Muscle Contraction"	"Calcium regulation in cardiac cells; Prostaglandin synthesis and regulation"	"3"	"0"	"454.2"	"357.5"	"539.4"	"489.1"	"526.0"	"508.0"	"1018.0"	"76.9"	"18541.2"	"21164.5"	"58473.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08211"	"ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4"	"0.000"	""	"36"	"36"	"90"	"36"	"1270"	"140.9"	"6.84"	"17400.41"	"195.34"	"28"	"31"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf00270, Pf00271, Pf04408, Pf07717"	"1660"	"ENSG00000135829"	"DHX9"	"B2RNV4; hsa:1660; Q05CI5; Q08211; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556"	"mRNA Splicing - Major Pathway; RIP-mediated NFkB activation via ZBP1; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"MECP2 and associated Rett syndrome; mRNA processing"	"5"	"0"	"1368.2"	"1220.9"	"1295.4"	"1217.7"	"1146.9"	"1123.7"	"3210.6"	"49.2"	"13884.2"	"14422.3"	"29770.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54577"	"Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4"	"0.000"	""	"74"	"43"	"98"	"43"	"528"	"59.1"	"7.05"	"15336.11"	"193.45"	"32"	"38"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00579, Pf01588"	"8565"	"ENSG00000134684"	"YARS1"	"B3KWK4; D3DPQ4; hsa:8565; O43276; P54577; Q53EN1"	"Cytosolic tRNA aminoacylation"	"Nephrotic syndrome"	"2"	"0"	"1280.3"	"1004.8"	"1419.9"	"1192.0"	"1314.9"	"1164.3"	"2308.7"	"111.1"	"26561.8"	"27056.1"	"58362.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7KZF4"	"Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1"	"0.000"	""	"41"	"34"	"78"	"34"	"910"	"101.9"	"7.17"	"14373.59"	"186.06"	"25"	"34"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00565, Pf00567"	"27044"	"ENSG00000197157"	"SND1"	"hsa:27044; Q13122; Q7KZF4; Q96AG0"	"Signaling by BRAF and RAF1 fusions"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"516.2"	"435.1"	"574.3"	"506.4"	"505.5"	"538.6"	"1378.6"	"39.5"	"12153.4"	"12372.8"	"28327.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03252"	"Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4"	"0.000"	""	"59"	"42"	"98"	"36"	"620"	"69.9"	"5.59"	"17294.27"	"180.02"	"37"	"40"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"84823"	"ENSG00000176619"	"LMNB2"	"hsa:84823; O75292; Q03252; Q14734; Q96DF6"	""	"Gastric cancer network 2; Fas ligand pathway and stress induction of heat shock proteins; IL-18 signaling pathway; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	"6"	"1"	"1546.4"	"955.0"	"1357.7"	"1240.0"	"1256.2"	"1413.5"	"2721.9"	"60.4"	"21803.5"	"20994.9"	"35098.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00839"	"Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6"	"0.000"	""	"47"	"38"	"101"	"38"	"825"	"90.5"	"6.00"	"18766.16"	"179.03"	"26"	"34"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00622, Pf02037, Pf13671"	"3192"	"ENSG00000153187"	"HNRNPU"	"hsa:3192; O75507; Q00839; Q8N174; Q96HY9; Q9BQ09"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"4"	"0"	"3903.3"	"3561.7"	"3574.0"	"3359.4"	"3334.7"	"3161.2"	"8233.4"	"53.8"	"23934.9"	"24612.4"	"44147.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61978"	"Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1"	"0.000"	""	"52"	"25"	"86"	"25"	"463"	"50.9"	"5.54"	"16673.77"	"177.25"	"20"	"24"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf08067"	"3190"	"ENSG00000165119"	"HNRNPK"	"hsa:3190; P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q6IBN1; Q922Y7; Q96J62"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; HCMV Late Events; SUMOylation of RNA binding proteins"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"6"	"0"	"2376.5"	"1890.6"	"2494.9"	"2246.7"	"2273.6"	"2216.8"	"4544.2"	"98.3"	"20504.6"	"20610.4"	"38952.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43491"	"Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1"	"0.000"	""	"41"	"37"	"81"	"33"	"1005"	"112.5"	"5.44"	"13248.64"	"177.14"	"30"	"34"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2037"	"ENSG00000079819"	"EPB41L2"	"B4DHI8; E9PPD9; hsa:2037; O43491; Q5T4F0; Q68DV2"	"Neurexins and neuroligins"	"Splicing factor NOVA regulated synaptic proteins"	"2"	"6"	"1304.9"	"1002.0"	"1187.2"	"1135.8"	"1014.6"	"1107.9"	"1943.5"	"45.9"	"20743.6"	"20528.5"	"42967.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09874"	"Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4"	"0.000"	""	"38"	"37"	"92"	"37"	"1014"	"113.0"	"8.88"	"15314.02"	"169.37"	"30"	"36"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063"	"142"	"ENSG00000143799"	"PARP1"	"B1ANJ4; hsa:142; P09874; Q8IUZ9"	"SUMOylation of DNA damage response and repair proteins; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through MMEJ (alt-NHEJ); Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; vRNA Synthesis; POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER"	"Corticotropin-releasing hormone signaling pathway; Nanoparticle triggered regulated necrosis; Fas ligand pathway and stress induction of heat shock proteins; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Breast cancer pathway; Acute viral myocarditis; Joubert syndrome; Male infertility; Base excision repair; IL-18 signaling pathway; DNA repair pathways, full network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Progeria-associated lipodystrophy; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling"	"25"	"0"	"1054.6"	"859.4"	"1174.0"	"1078.1"	"1123.4"	"1135.2"	"2209.1"	"88.1"	"27471.8"	"27833.1"	"55445.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11142"	"Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1"	"0.000"	""	"55"	"36"	"90"	"30"	"646"	"70.9"	"5.52"	"15074.94"	"168.26"	"30"	"34"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3312"	"ENSG00000109971"	"HSPA8"	"hsa:3312; P11142; Q9H3R6"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Attenuation phase; Clathrin-mediated endocytosis; Late endosomal microautophagy; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Lysosome Vesicle Biogenesis; mRNA Splicing - Major Pathway; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; GABA synthesis, release, reuptake and degradation; Lipophagy; Chaperone Mediated Autophagy; Protein methylation"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Exercise-induced circadian regulation; Measles virus infection; Opioid receptor pathways; Extrafollicular and follicular B cell activation by SARS-CoV-2; 1p36 copy number variation syndrome"	"24"	"7"	"2839.5"	"2024.8"	"3047.1"	"2694.3"	"2508.4"	"2607.8"	"4233.9"	"39.4"	"23597.4"	"22981.8"	"45096.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ80"	"Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3"	"0.000"	""	"60"	"24"	"77"	"24"	"394"	"43.8"	"6.55"	"12447.05"	"163.34"	"18"	"22"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00557"	"5036"	"ENSG00000170515"	"PA2G4"	"hsa:5036; O43846; Q9UM59; Q9UQ80"	"Neutrophil degranulation"	""	"1"	"0"	"479.1"	"319.4"	"513.7"	"478.6"	"472.1"	"458.1"	"789.6"	"53.3"	"15691.0"	"17794.7"	"30969.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2J2"	"Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2"	"0.000"	""	"32"	"34"	"78"	"29"	"1087"	"120.6"	"5.19"	"14014.09"	"158.82"	"28"	"31"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"23136"	"ENSG00000082397"	"EPB41L3"	"B7Z4I5; F5GX05; hsa:23136; O95713; Q9BRP5; Q9Y2J2"	"Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"Splicing factor NOVA regulated synaptic proteins"	"4"	"1"	"850.7"	"653.7"	"796.5"	"778.5"	"779.3"	"739.9"	"1399.9"	"64.1"	"16125.2"	"16317.3"	"19783.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95602"	"DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2"	"0.000"	""	"28"	"34"	"63"	"33"	"1720"	"194.7"	"7.03"	"10874.35"	"152.81"	"24"	"33"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"25885"	"ENSG00000068654"	"POLR1A"	"B7Z7T0; D6W5M0; hsa:25885; O95602; Q0VG05; Q9UEH0; Q9UFT9"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"1"	"440.9"	"314.1"	"475.6"	"423.7"	"455.5"	"436.5"	"1011.0"	"25.9"	"15905.3"	"15474.1"	"29090.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99459"	"Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2"	"0.000"	""	"49"	"33"	"69"	"33"	"802"	"92.2"	"8.18"	"13240.82"	"152.43"	"26"	"28"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11831, Pf13921"	"988"	"ENSG00000096401"	"CDC5L"	"hsa:988; Q76N46; Q99459; Q99974"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"905.2"	"666.1"	"971.6"	"891.1"	"825.6"	"892.1"	"2038.1"	"39.4"	"16359.9"	"16234.3"	"31837.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75643"	"U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2"	"0.000"	""	"21"	"40"	"70"	"40"	"2136"	"244.4"	"6.06"	"12521.19"	"149.89"	"29"	"34"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf02889, Pf18149"	"23020"	"ENSG00000144028"	"SNRNP200"	"hsa:23020; O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2q11.2 copy number variation syndrome"	"3"	"0"	"813.7"	"683.4"	"888.6"	"785.5"	"751.1"	"701.9"	"2081.7"	"49.0"	"12694.9"	"13298.9"	"33185.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14980"	"Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2"	"0.000"	""	"24"	"43"	"78"	"41"	"2115"	"238.1"	"5.78"	"15768.18"	"149.50"	"36"	"38"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"4926"	"ENSG00000137497"	"NUMA1"	"H0YH75; hsa:4926; Q14980; Q14981; Q9BTE9"	"Recruitment of NuMA to mitotic centrosomes; Mitotic Prophase"	"Ectoderm differentiation; Ectoderm differentiation; 8p23.1 copy number variation syndrome"	"5"	"2"	"1509.3"	"1048.5"	"1511.2"	"1464.2"	"1274.6"	"1336.9"	"3300.0"	"31.9"	"15456.3"	"15426.5"	"28320.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P2Q9"	"Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2"	"0.000"	""	"18"	"36"	"70"	"36"	"2335"	"273.4"	"8.84"	"10817.17"	"143.68"	"25"	"34"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134"	"10594"	"ENSG00000174231; ENSG00000274442"	"PRPF8"	"hsa:10594; O14547; O75965; Q6P2Q9"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"814.4"	"667.8"	"874.1"	"738.8"	"810.4"	"749.8"	"1998.4"	"34.9"	"13245.0"	"14700.8"	"34732.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23284"	"Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2"	"0.000"	""	"63"	"20"	"80"	"19"	"216"	"23.7"	"9.41"	"14642.34"	"143.30"	"18"	"19"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"5479"	"ENSG00000166794"	"PPIB"	"A8K534; hsa:5479; P23284; Q6IBH5; Q9BVK5"	"Collagen biosynthesis and modifying enzymes; SARS-CoV-1 activates/modulates innate immune responses"	"Prolactin signaling pathway; Type I collagen synthesis in the context of osteogenesis imperfecta"	"4"	"1"	"583.1"	"468.5"	"720.7"	"599.6"	"874.0"	"1035.3"	"3543.8"	"61.7"	"21763.0"	"22048.6"	"28383.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92841"	"Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2"	"0.000"	""	"40"	"28"	"73"	"20"	"729"	"80.2"	"8.27"	"13470.27"	"143.19"	"24"	"27"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"10521"	"ENSG00000100201"	"DDX17"	"B1AHM0; H3BLZ8; hsa:10521; Q69YT1; Q6ICD6; Q92841"	"SUMOylation of transcription cofactors"	"Novel intracellular components of RIG-I-like receptor pathway"	"2"	"7"	"1672.2"	"1303.0"	"1613.3"	"1471.1"	"1305.7"	"1402.3"	"3798.7"	"17.8"	"10890.0"	"11008.7"	"21481.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55196"	"Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3"	"0.000"	""	"21"	"33"	"62"	"33"	"1824"	"206.7"	"6.47"	"10521.26"	"142.69"	"24"	"31"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00498, Pf00595, Pf00788, Pf01843"	"4301"	"ENSG00000130396"	"AFDN"	"hsa:4301; O75087; O75088; O75089; P55196; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92"	""	"VEGFA-VEGFR2 signaling; Ras signaling; 1q21.1 copy number variation syndrome"	"3"	"0"	"640.1"	"456.0"	"625.9"	"588.6"	"528.5"	"573.5"	"1120.2"	"25.1"	"15783.6"	"15820.4"	"29770.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07814"	"Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5"	"0.000"	""	"28"	"33"	"55"	"32"	"1512"	"170.5"	"7.33"	"8928.13"	"141.35"	"19"	"30"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf00587, Pf00749, Pf03129, Pf03950, Pf09180"	"2058"	"ENSG00000136628"	"EPRS1"	"A0AVA9; B9EGH3; hsa:2058; P07814; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73"	"tRNA modification in the nucleus and cytosol; Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Parkinson's disease pathway; VEGFA-VEGFR2 signaling; Amino acid metabolism"	"6"	"1"	"962.9"	"739.9"	"886.1"	"920.5"	"855.8"	"708.7"	"1145.0"	"36.1"	"12180.7"	"12392.8"	"29836.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11171"	"Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4"	"0.000"	""	"38"	"34"	"77"	"31"	"864"	"97.0"	"5.58"	"14804.61"	"140.06"	"32"	"29"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2035"	"ENSG00000159023"	"EPB41"	"B1ALH8; B1ALH9; D3DPM9; D3DPN0; hsa:2035; P11171; P11176; Q14245; Q5TB35; Q5VXN8; Q8IXV9; Q9Y578; Q9Y579"	"Neurexins and neuroligins"	"VEGFA-VEGFR2 signaling; Splicing factor NOVA regulated synaptic proteins; IL-18 signaling pathway"	"4"	"1"	"799.5"	"585.8"	"884.7"	"794.9"	"760.7"	"873.7"	"1534.6"	"46.4"	"30639.7"	"29592.7"	"30969.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25205"	"DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3"	"0.000"	""	"43"	"27"	"55"	"27"	"808"	"90.9"	"5.77"	"9035.34"	"136.13"	"19"	"26"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4172"	"ENSG00000112118"	"MCM3"	"B4DWW4; hsa:4172; P25205; Q92660; Q9BTR3; Q9NUE7"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"11"	"0"	"675.2"	"568.9"	"701.1"	"616.7"	"620.1"	"618.8"	"1574.5"	"28.0"	"9758.1"	"10072.1"	"25941.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26639"	"Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3"	"0.000"	""	"47"	"31"	"63"	"31"	"723"	"83.4"	"6.67"	"8976.15"	"135.84"	"20"	"29"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"6897"	"ENSG00000113407"	"TARS1"	"A8K8I1; B4DEG8; hsa:6897; P26639; Q96FP5; Q9BWA6"	"Cytosolic tRNA aminoacylation"	""	"1"	"0"	"242.4"	"167.1"	"293.1"	"252.5"	"265.6"	"374.2"	"1612.5"	"57.3"	"14641.1"	"14109.1"	"30560.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43776"	"Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1"	"0.000"	""	"43"	"26"	"65"	"26"	"548"	"62.9"	"6.25"	"12719.72"	"135.20"	"22"	"23"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"4677"	"ENSG00000134440"	"NARS1"	"B4DG16; hsa:4677; O43776; Q53GU6"	"Cytosolic tRNA aminoacylation"	"Photodynamic therapy-induced unfolded protein response"	"2"	"0"	"848.2"	"679.3"	"901.5"	"819.4"	"847.7"	"800.0"	"1519.8"	"50.6"	"17941.5"	"17859.2"	"35503.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31943"	"Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4"	"0.000"	""	"44"	"17"	"62"	"8"	"449"	"49.2"	"6.30"	"10858.13"	"132.43"	"12"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08080"	"3187"	"ENSG00000169045; ENSG00000284254"	"HNRNPH1"	"B3KW86; D3DWQ2; hsa:3187; P31943; Q6IBM4"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"MECP2 and associated Rett syndrome; mRNA processing; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"6"	"10"	"1403.9"	"1188.5"	"1243.1"	"1114.0"	"1144.6"	"1190.1"	"3052.8"	"38.1"	"14154.2"	"14352.5"	"23222.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DMV9"	"Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B PE=1 SV=1"	"0.000"	""	"57"	"30"	"64"	"25"	"641"	"70.0"	"5.66"	"10488.03"	"132.41"	"24"	"29"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3303; 3304"	"ENSG00000204388; ENSG00000212866; ENSG00000224501; ENSG00000231555; ENSG00000232804"	"HSPA1B"	"B4E3B6; hsa:3303; hsa:3304; P08107; P0DMV9; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0"	"Regulation of HSF1-mediated heat shock response; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Neutrophil degranulation; Attenuation phase"	"Apoptosis modulation and signaling; Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Measles virus infection; CKAP4 signaling pathway map"	"12"	"0"	"1781.6"	"1354.1"	"1631.8"	"1599.7"	"1437.9"	"1551.4"	"2274.1"	"28.7"	"12087.4"	"9647.9"	"24938.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63010"	"AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1"	"0.000"	""	"29"	"27"	"65"	"15"	"937"	"104.5"	"5.38"	"11284.15"	"132.18"	"22"	"24"	"transport;developmental processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02883, Pf09066"	"163"	"ENSG00000006125"	"AP2B1"	"A6NJP3; hsa:163; P21851; P63010; Q7Z451; Q96J19"	"Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; WNT5A-dependent internalization of FZD4; Retrograde neurotrophin signalling; Potential therapeutics for SARS; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission; Markers of kidney cell lineage; 17q12 copy number variation syndrome"	"20"	"14"	"293.5"	"200.8"	"342.7"	"300.5"	"335.6"	"402.6"	"1366.1"	"58.7"	"17147.6"	"16984.8"	"28048.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46940"	"Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1"	"0.000"	""	"23"	"28"	"49"	"26"	"1657"	"189.1"	"6.48"	"8356.78"	"130.90"	"18"	"26"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"8826"	"ENSG00000140575"	"IQGAP1"	"A7MBM3; hsa:8826; P46940"	"Signaling by BRAF and RAF1 fusions; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RHOV GTPase cycle; Neutrophil degranulation; RHOU GTPase cycle; Nephrin family interactions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ciliary landscape; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"25"	"2"	"231.9"	"169.5"	"313.0"	"235.9"	"330.0"	"275.7"	"546.2"	"56.1"	"9375.7"	"9371.4"	"22686.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14618"	"Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4"	"0.000"	""	"54"	"21"	"41"	"21"	"531"	"57.9"	"7.84"	"6407.80"	"130.04"	"11"	"20"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00224, Pf02887"	"5315"	"ENSG00000067225"	"PKM"	"A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; hsa:5315; P14618; P14786; Q53GK4; Q96E76; Q9BWB5; Q9UCV6; Q9UPF2"	"Neutrophil degranulation"	"Photodynamic therapy-induced HIF-1 survival signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"10"	"0"	"337.3"	"244.7"	"371.0"	"307.7"	"348.2"	"287.3"	"589.3"	"24.5"	"7068.5"	"7732.3"	"19857.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14866"	"Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2"	"0.000"	""	"46"	"17"	"56"	"16"	"589"	"64.1"	"8.22"	"9958.52"	"129.93"	"11"	"17"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"3191"	"ENSG00000104824; ENSG00000282947"	"HNRNPL"	"A6ND69; A6NIT8; hsa:3191; P14866; Q9H3P3"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing; Hippocampal synaptogenesis and neurogenesis"	"4"	"1"	"2467.0"	"2262.7"	"2168.3"	"2364.1"	"2017.3"	"1640.7"	"4083.5"	"24.1"	"9198.8"	"8460.8"	"14971.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12906"	"Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3"	"0.000"	""	"33"	"25"	"61"	"22"	"894"	"95.3"	"8.76"	"10499.70"	"128.70"	"20"	"25"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf07528"	"3609"	"ENSG00000129351"	"ILF3"	"A8K6F2; G5E9M5; hsa:3609; O43409; Q12906; Q6P1X1; Q86XY7; Q99544; Q99545; Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0; Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84; Q9UNA2"	"Regulation of CDH11 gene transcription"	""	"1"	"3"	"969.8"	"925.9"	"1116.1"	"1008.5"	"980.6"	"884.2"	"2913.8"	"36.8"	"9074.9"	"9082.8"	"14839.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00571"	"ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3"	"0.000"	""	"50"	"30"	"66"	"29"	"662"	"73.2"	"7.18"	"11378.02"	"124.24"	"25"	"29"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1654"	"ENSG00000215301"	"DDX3X"	"A8K538; B4E3E8; hsa:1654; O00571; O15536"	"Neutrophil degranulation"	"Novel intracellular components of RIG-I-like receptor pathway; Hepatitis B infection"	"3"	"1"	"1530.9"	"1168.2"	"1426.3"	"1256.9"	"1203.9"	"1300.0"	"4604.0"	"39.1"	"14030.4"	"13572.0"	"25996.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JRX3"	"Presequence protease, mitochondrial OS=Homo sapiens OX=9606 GN=PITRM1 PE=1 SV=3"	"0.000"	""	"30"	"24"	"47"	"24"	"1037"	"117.3"	"6.92"	"8332.33"	"121.02"	"15"	"22"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00675, Pf05193, Pf08367"	"10531"	"ENSG00000107959"	"PITRM1"	"B3KMJ6; B4E0J8; C9JSL2; E7ES23; hsa:10531; O95204; Q2M2G6; Q4VBR1; Q5JRW7; Q5JRX3; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8"	"Mitochondrial protein import"	""	"1"	"0"	"162.1"	"115.5"	"195.3"	"171.6"	"179.1"	"181.6"	"419.4"	"37.0"	"11735.0"	"11852.9"	"23684.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38646"	"Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2"	"0.000"	""	"41"	"25"	"58"	"24"	"679"	"73.6"	"6.16"	"9553.55"	"120.10"	"20"	"24"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00012"	"3313"	"ENSG00000113013"	"HSPA9"	"B2RCM1; hsa:3313; P30036; P31932; P38646; Q1HB43; Q53H23; Q6GU03; Q9BWB7; Q9UC56"	"Mitochondrial protein import; Regulation of HSF1-mediated heat shock response; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Cristae formation"	"Parkin-ubiquitin proteasomal system pathway; Iron-sulfur cluster biogenesis"	"6"	"0"	"1825.9"	"1500.3"	"1817.4"	"1689.1"	"1855.3"	"1550.2"	"2109.1"	"30.8"	"11714.7"	"11488.5"	"20515.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43390"	"Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1"	"0.000"	""	"43"	"25"	"59"	"15"	"633"	"70.9"	"8.13"	"10390.25"	"120.01"	"21"	"24"	"RNA metabolism OR transcription;other metabolic processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10236"	"ENSG00000125944; ENSG00000282958"	"HNRNPR"	"hsa:10236; O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"10"	"1769.8"	"1722.7"	"1814.0"	"1664.8"	"1703.3"	"1506.3"	"3590.7"	"14.8"	"10882.0"	"10716.0"	"18611.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35579"	"Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4"	"0.000"	""	"19"	"30"	"50"	"24"	"1960"	"226.4"	"5.60"	"8864.52"	"120.00"	"21"	"27"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4627"	"ENSG00000100345"	"MYH9"	"A8K6E4; hsa:4627; O60805; P35579; Q60FE2; Q86T83"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by ALK fusions and activated point mutants; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs; CD163 mediating an anti-inflammatory response"	"Primary focal segmental glomerulosclerosis (FSGS); VEGFA-VEGFR2 signaling; Nephrotic syndrome"	"16"	"6"	"277.9"	"202.5"	"340.9"	"284.5"	"303.8"	"312.5"	"576.9"	"37.8"	"6850.6"	"7311.3"	"19754.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15149"	"Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3"	"0.000"	""	"9"	"32"	"57"	"28"	"4684"	"531.5"	"5.96"	"9407.89"	"119.95"	"24"	"32"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00681, Pf03501, Pf17902, Pf18373"	"5339"	"ENSG00000178209"	"PLEC"	"hsa:5339; Q15148; Q15149; Q16640; Q6S376; Q6S377; Q6S378; Q6S379; Q6S380; Q6S381; Q6S382; Q6S383"	"Assembly of collagen fibrils and other multimeric structures; Caspase-mediated cleavage of cytoskeletal proteins; Type I hemidesmosome assembly"	"Envelope proteins and their potential roles in EDMD physiopathology"	"4"	"4"	"721.6"	"531.1"	"744.5"	"697.5"	"682.1"	"679.6"	"1418.0"	"35.1"	"7042.5"	"7018.4"	"14306.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46013"	"Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2"	"0.000"	""	"14"	"32"	"65"	"32"	"3256"	"358.5"	"9.45"	"12986.44"	"118.60"	"32"	"30"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08065, Pf15276"	"4288"	"ENSG00000148773"	"MKI67"	"hsa:4288; P46013; Q5VWH2"	""	"Primary focal segmental glomerulosclerosis (FSGS)"	"1"	"0"	"1205.0"	"997.1"	"1188.1"	"1122.5"	"1016.4"	"1211.2"	"3201.1"	"25.9"	"11661.9"	"11622.7"	"22421.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4VCS5"	"Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1"	"0.000"	""	"32"	"28"	"57"	"28"	"1084"	"118.0"	"7.64"	"9616.59"	"118.43"	"21"	"27"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12240"	"154796"	"ENSG00000126016"	"AMOT"	"hsa:154796; Q4VCS5; Q504X5; Q9HD27; Q9UPT1"	""	"VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"3"	"0"	"986.9"	"857.9"	"937.5"	"955.1"	"856.6"	"950.4"	"1983.6"	"19.7"	"8740.5"	"8704.5"	"15801.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51991"	"Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2"	"0.000"	""	"47"	"17"	"60"	"15"	"378"	"39.6"	"9.01"	"9986.23"	"118.21"	"10"	"16"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00076"	"220988"	"ENSG00000170144"	"HNRNPA3"	"D3DPF4; hsa:220988; P51991; Q53RW7; Q6URK5"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	""	"2"	"0"	"1348.4"	"1321.8"	"1232.1"	"1223.2"	"1036.6"	"1062.8"	"2916.6"	"7.9"	"5843.3"	"6092.8"	"9302.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06748"	"Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2"	"0.000"	""	"57"	"19"	"65"	"19"	"294"	"32.6"	"4.78"	"12185.09"	"117.68"	"17"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03066, Pf16276"	"4869"	"ENSG00000181163"	"NPM1"	"A8K3N7; B5BU00; D3DQL6; hsa:4869; P06748; P08693; Q12826; Q13440; Q13441; Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962; Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Nuclear import of Rev protein; Deposition of new CENPA-containing nucleosomes at the centromere; SUMOylation of transcription cofactors; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SARS-CoV-1-host interactions"	""	"9"	"0"	"4687.2"	"3661.9"	"4221.9"	"4062.5"	"3283.8"	"3614.3"	"6983.2"	"14.3"	"18970.6"	"18925.8"	"33299.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14103"	"Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1"	"0.000"	""	"35"	"19"	"68"	"16"	"355"	"38.4"	"7.81"	"11782.90"	"116.50"	"17"	"18"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3184"	"ENSG00000138668"	"HNRNPD"	"A8K9J2; hsa:3184; P07029; Q01858; Q14100; Q14101; Q14102; Q14103; Q4W5A1; Q9UCE8; Q9UCE9"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"5"	"3618.3"	"2812.0"	"3501.8"	"3281.1"	"2609.8"	"2597.3"	"8499.8"	"52.8"	"17174.6"	"15126.7"	"25739.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60841"	"Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4"	"0.000"	""	"26"	"26"	"46"	"26"	"1220"	"138.7"	"5.49"	"7501.65"	"116.38"	"16"	"26"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf11987"	"9669"	"ENSG00000158417"	"EIF5B"	"hsa:9669; O60841; O95805; Q53RV7; Q53SI8; Q9UF81; Q9UMN7"	"GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; Ciliary landscape"	"3"	"0"	"237.4"	"164.1"	"274.8"	"253.1"	"245.6"	"247.0"	"446.8"	"26.7"	"9818.5"	"9943.5"	"21448.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00159"	"Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4"	"0.000"	""	"28"	"25"	"53"	"24"	"1063"	"121.6"	"9.41"	"8847.69"	"113.89"	"20"	"24"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4641"	"ENSG00000197879"	"MYO1C"	"hsa:4641; O00159; Q4LE56; Q6NVJ7; Q86Y95"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"VEGFA-VEGFR2 signaling; Insulin signaling; 10q11.21q11.23 copy number variation syndrome"	"8"	"1"	"258.6"	"182.7"	"303.0"	"255.9"	"262.5"	"277.3"	"716.2"	"18.5"	"9297.7"	"9331.9"	"18096.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54136"	"Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2"	"0.000"	""	"43"	"23"	"44"	"23"	"660"	"75.3"	"6.68"	"8162.57"	"111.81"	"14"	"23"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00750, Pf03485, Pf05746"	"5917"	"ENSG00000113643"	"RARS1"	"B2RBS9; hsa:5917; P54136; Q53GY4; Q9BWA1"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"Amino acid metabolism"	"3"	"0"	"168.3"	"117.3"	"208.3"	"163.6"	"173.6"	"170.4"	"363.2"	"52.6"	"6828.9"	"6926.1"	"16506.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68104"	"Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1"	"0.000"	""	"49"	"17"	"47"	"9"	"462"	"50.1"	"9.01"	"5918.47"	"111.71"	"12"	"14"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1915"	"ENSG00000156508"	"EEF1A1"	"hsa:1915; P04719; P04720; P68104; Q6IQ15"	"Peptide chain elongation; Neutrophil degranulation; Chaperone Mediated Autophagy; Protein methylation; HSF1 activation; SARS-CoV-1 modulates host translation machinery"	"Translation factors; Fragile X syndrome; 2q37 copy number variation syndrome"	"10"	"11"	"707.5"	"625.8"	"684.1"	"645.6"	"639.9"	"915.6"	"1950.9"	"39.2"	"14439.7"	"16850.5"	"26125.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04406"	"Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3"	"0.000"	""	"64"	"21"	"43"	"21"	"335"	"36.0"	"8.46"	"5986.68"	"110.72"	"14"	"19"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00044, Pf02800"	"2597"	"ENSG00000111640"	"GAPDH"	"E7EUT4; hsa:2597; P00354; P04406; Q53X65"	"Glycolysis; Gluconeogenesis"	"Cori cycle; Alzheimer's disease and miRNA effects; HIF1A and PPARG regulation of glycolysis; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; 7q11.23 copy number variation syndrome; Glycolysis in senescence; Alzheimer's disease; Sildenafil treatment; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"16"	"0"	"1575.3"	"1604.6"	"2030.4"	"1613.2"	"1566.7"	"1649.4"	"3791.9"	"39.6"	"13144.0"	"12760.1"	"23063.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35611"	"Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2"	"0.000"	""	"30"	"22"	"44"	"19"	"737"	"80.9"	"5.83"	"7538.80"	"110.64"	"14"	"22"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"118"	"ENSG00000087274"	"ADD1"	"A2A3N8; A2A3P0; B4DI79; D3DVR3; D3DVR4; D3DVR5; hsa:118; P35611; Q13734; Q14729; Q16156; Q86XM2; Q9UJB6"	"XBP1(S) activates chaperone genes; Caspase-mediated cleavage of cytoskeletal proteins; Miscellaneous transport and binding events"	""	"3"	"3"	"441.1"	"304.2"	"481.1"	"486.6"	"454.5"	"393.5"	"660.5"	"27.8"	"9244.6"	"8819.2"	"18313.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07157"	"Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3"	"0.000"	""	"19"	"26"	"52"	"26"	"1748"	"195.3"	"6.70"	"9110.65"	"109.37"	"20"	"24"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf00791, Pf07653"	"7082"	"ENSG00000104067; ENSG00000277401"	"TJP1"	"B4E3K1; hsa:7082; Q07157; Q2NKP3; Q4ZGJ6"	"RUNX1 regulates expression of components of tight junctions; Signaling by Hippo; Regulation of gap junction activity; SARS-CoV-2 targets PDZ proteins in cell-cell junction; Apoptotic cleavage of cell adhesion  proteins"	"Epithelial to mesenchymal transition in colorectal cancer; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; Disruption of postsynaptic signaling by CNV; 1q21.1 copy number variation syndrome; CKAP4 signaling pathway map; 15q11q13 copy number variation"	"12"	"0"	"583.6"	"418.1"	"593.9"	"544.2"	"518.5"	"556.0"	"1127.7"	"37.1"	"10333.1"	"9894.1"	"20568.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22102"	"Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1"	"0.000"	""	"27"	"26"	"46"	"26"	"1010"	"107.7"	"6.70"	"7890.68"	"108.96"	"18"	"24"	"other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00551, Pf00586, Pf01071, Pf02769, Pf02843, Pf02844"	"2618"	"ENSG00000159131; ENSG00000262473"	"GART"	"A8K945; A8KA32; D3DSF3; D3DSF4; hsa:2618; O14659; P22102; Q52M77"	"Purine ribonucleoside monophosphate biosynthesis"	"Folate metabolism; One-carbon metabolism; Metabolic reprogramming in colon cancer"	"4"	"0"	"296.8"	"233.0"	"366.0"	"320.9"	"368.2"	"584.0"	"1590.4"	"16.8"	"10497.9"	"11321.6"	"23326.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEY8"	"Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1"	"0.000"	""	"32"	"21"	"48"	"19"	"706"	"79.1"	"6.32"	"7186.71"	"108.76"	"11"	"21"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"120"	"ENSG00000148700"	"ADD3"	"D3DRA8; hsa:120; O43243; Q5VU09; Q92773; Q9UEY7; Q9UEY8"	"Miscellaneous transport and binding events; RHOD GTPase cycle; RHOF GTPase cycle"	""	"3"	"0"	"278.3"	"214.8"	"240.9"	"232.6"	"249.5"	"271.0"	"433.6"	"20.3"	"6790.3"	"6842.4"	"13439.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35221"	"Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1"	"0.000"	""	"34"	"25"	"50"	"25"	"906"	"100.0"	"6.29"	"8479.69"	"108.58"	"18"	"25"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"1495"	"ENSG00000044115"	"CTNNA1"	"hsa:1495; P35221; Q12795; Q8N1C0"	"RHO GTPases activate IQGAPs; Myogenesis; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"Arrhythmogenic right ventricular cardiomyopathy; Apoptosis-related network due to altered Notch3 in ovarian cancer; VEGFA-VEGFR2 signaling; White fat cell differentiation; Endometrial cancer; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"15"	"0"	"287.9"	"199.0"	"349.8"	"304.8"	"333.9"	"304.7"	"564.1"	"53.0"	"9245.8"	"9503.2"	"20502.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00558"	"Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3"	"0.000"	""	"65"	"26"	"53"	"26"	"417"	"44.6"	"8.10"	"8516.83"	"108.51"	"19"	"24"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00162"	"5230"	"ENSG00000102144"	"PGK1"	"A8K4W6; B7Z7A9; hsa:5230; P00558; Q5J7W1; Q6IBT6; Q8NI87"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"13"	"0"	"205.9"	"121.4"	"283.2"	"213.8"	"234.4"	"201.0"	"428.8"	"41.9"	"18598.9"	"20024.7"	"31635.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNX4"	"WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1"	"0.000"	""	"35"	"26"	"49"	"26"	"943"	"106.0"	"6.64"	"9024.88"	"107.68"	"21"	"24"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf04003, Pf12894"	"10885"	"ENSG00000065183"	"WDR3"	"hsa:10885; Q9UNX4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"358.9"	"277.5"	"373.6"	"314.5"	"354.9"	"362.1"	"609.3"	"19.2"	"11698.9"	"12214.4"	"20864.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13435"	"Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2"	"0.000"	""	"25"	"20"	"48"	"20"	"895"	"100.2"	"5.67"	"7867.74"	"107.11"	"15"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02037, Pf04037, Pf04046"	"10992"	"ENSG00000087365"	"SF3B2"	"A8K485; B4DT19; hsa:10992; Q13435; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"1267.6"	"953.4"	"1194.6"	"1116.9"	"975.6"	"1118.4"	"2781.0"	"22.0"	"6762.3"	"6563.6"	"12564.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15029"	"116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1"	"0.000"	""	"33"	"25"	"49"	"24"	"972"	"109.4"	"5.00"	"8344.94"	"106.79"	"18"	"24"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492, Pf16004"	"9343"	"ENSG00000108883"	"EFTUD2"	"B4DK30; B4DMC0; D3DX58; hsa:9343; K7EJ81; Q15029; Q9BUR0"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing; Ciliary landscape"	"4"	"0"	"813.3"	"620.0"	"790.8"	"707.0"	"664.8"	"671.5"	"1870.2"	"21.8"	"10417.4"	"10939.9"	"23551.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33992"	"DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5"	"0.000"	""	"40"	"25"	"58"	"25"	"734"	"82.2"	"8.37"	"11593.42"	"103.64"	"22"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4174"	"ENSG00000100297"	"MCM5"	"hsa:4174; O60785; P33992; Q14578; Q9BTJ4; Q9BWL8"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"10"	"0"	"437.0"	"321.7"	"536.5"	"471.2"	"500.0"	"450.7"	"1046.5"	"19.7"	"8725.2"	"9000.3"	"25604.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01081"	"Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3"	"0.000"	""	"40"	"10"	"31"	"10"	"240"	"27.9"	"8.81"	"4600.39"	"101.33"	"4"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	"102724594; 7307"	"ENSG00000160201"	"U2AF1"	"hsa:102724594; hsa:7307; Q01081; Q701P4; Q71RF1"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"mRNA processing"	"5"	"0"	"232.1"	"176.2"	"249.2"	"236.8"	"210.3"	"154.6"	"518.2"	"13.5"	"6309.8"	"7027.7"	"12644.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60264"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1"	"0.000"	""	"25"	"27"	"49"	"14"	"1052"	"121.8"	"8.09"	"8052.29"	"99.53"	"20"	"27"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"8467"	"ENSG00000153147"	"SMARCA5"	"hsa:8467; O60264"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; NoRC negatively regulates rRNA expression"	"10q11.21q11.23 copy number variation syndrome"	"5"	"13"	"453.3"	"355.8"	"455.2"	"434.0"	"394.1"	"470.2"	"1182.0"	"26.5"	"10310.6"	"8987.3"	"24069.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07910"	"Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4"	"0.000"	""	"37"	"14"	"59"	"12"	"306"	"33.7"	"5.08"	"11446.04"	"98.89"	"12"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3183"	"ENSG00000092199"	"HNRNPC"	"D3DS19; D3DS22; hsa:3183; P07910; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3"	"Processing of Capped Intron-Containing Pre-mRNA; SUMOylation of RNA binding proteins; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"6"	"2"	"2997.2"	"2671.7"	"2852.4"	"2679.0"	"2363.7"	"2831.5"	"5270.0"	"78.0"	"9348.9"	"9550.9"	"14976.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95782"	"AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3"	"0.000"	""	"29"	"22"	"48"	"16"	"977"	"107.5"	"7.03"	"6639.99"	"98.19"	"18"	"21"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01602, Pf02296, Pf02883"	"160"	"ENSG00000196961"	"AP2A1"	"hsa:160; O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070"	"MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Trafficking of GluR2-containing AMPA receptors; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission"	"20"	"5"	"249.9"	"161.0"	"295.3"	"279.6"	"298.7"	"339.2"	"1041.0"	"22.2"	"9272.0"	"9654.7"	"14287.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07437"	"Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2"	"0.000"	""	"39"	"15"	"43"	"1"	"444"	"49.6"	"4.89"	"7493.59"	"98.16"	"13"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"203068"	"ENSG00000183311; ENSG00000196230; ENSG00000224156; ENSG00000227739; ENSG00000229684; ENSG00000232421; ENSG00000232575; ENSG00000235067"	"TUBB"	"hsa:203068; P05218; P07437; Q8WUC1; Q9CY33"	"Potential therapeutics for SARS; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Opioid receptor pathways; Alzheimer's disease"	"14"	"2"	"81.4"	"74.9"	"62.6"	"64.3"	"53.8"	"62.0"	"90.5"	"0.6"	"785.8"	"819.2"	"1473.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26038"	"Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3"	"0.000"	""	"49"	"31"	"59"	"20"	"577"	"67.8"	"6.40"	"10254.73"	"98.10"	"24"	"26"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4478"	"ENSG00000147065"	"MSN"	"hsa:4478; P26038"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Signaling by ALK fusions and activated point mutants"	"Glial cell differentiation; AGE/RAGE pathway; Measles virus infection; 16p11.2 proximal deletion syndrome; Regulation of actin cytoskeleton"	"10"	"11"	"625.1"	"424.4"	"757.5"	"628.2"	"825.6"	"701.7"	"1193.7"	"38.2"	"18839.5"	"18265.9"	"33748.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NE71"	"ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2"	"0.000"	""	"25"	"20"	"49"	"19"	"845"	"95.9"	"6.80"	"10157.67"	"97.66"	"17"	"17"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00005, Pf12848"	"23"	"ENSG00000204574; ENSG00000206490; ENSG00000225989; ENSG00000231129; ENSG00000232169; ENSG00000236149; ENSG00000236342"	"ABCF1"	"A2BF75; hsa:23; O14897; Q69YP6; Q8NE71"	"ABC-family proteins mediated transport"	"IL-18 signaling pathway"	"2"	"1"	"570.5"	"427.5"	"581.2"	"545.2"	"520.3"	"553.2"	"860.4"	"28.2"	"15935.8"	"15912.7"	"26101.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21333"	"Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4"	"0.000"	""	"11"	"22"	"36"	"21"	"2647"	"280.6"	"6.06"	"5669.69"	"97.35"	"12"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2316"	"ENSG00000196924"	"FLNA"	"E9KL45; hsa:2316; P21333; Q5HY53; Q5HY55; Q8NF52"	"OAS antiviral response; Platelet degranulation ; RHO GTPases activate PAKs; GP1b-IX-V activation signalling; Cell-extracellular matrix interactions"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Focal adhesion; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; IL-4 signaling pathway; Ebola virus infection in host; Joubert syndrome; NPHP1 deletion syndrome"	"14"	"1"	"362.7"	"259.7"	"375.4"	"360.5"	"310.7"	"328.2"	"506.4"	"11.7"	"5367.9"	"5602.1"	"14011.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41091"	"Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3"	"0.000"	""	"42"	"20"	"52"	"20"	"472"	"51.1"	"8.40"	"8733.04"	"97.30"	"15"	"19"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf09173"	"1968"	"ENSG00000130741"	"EIF2S3"	"A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4; hsa:1968; P41091; Q53HK3"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"12"	"0"	"346.1"	"266.6"	"370.3"	"329.2"	"348.5"	"337.0"	"867.6"	"90.8"	"16248.4"	"17161.8"	"24765.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63241"	"Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2"	"0.000"	""	"71"	"9"	"48"	"9"	"154"	"16.8"	"5.24"	"7547.56"	"97.22"	"5"	"9"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01287"	"1984"	"ENSG00000132507; ENSG00000288145"	"EIF5A"	"A8K9A0; D3DTP2; hsa:1984; P10159; P63241; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2"	"Hypusine synthesis from eIF5A-lysine"	"Translation factors; eIF5A regulation in response to inhibition of the nuclear export system"	"3"	"0"	"116.3"	"77.2"	"160.7"	"106.0"	"134.3"	"136.2"	"339.1"	"33.0"	"9892.3"	"12047.1"	"16258.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42285"	"Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3"	"0.000"	""	"23"	"21"	"43"	"21"	"1042"	"117.7"	"6.52"	"5975.22"	"96.82"	"15"	"19"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08148, Pf13234"	"23517"	"ENSG00000039123"	"MTREX"	"hsa:23517; P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol"	""	"2"	"0"	"402.7"	"312.9"	"459.6"	"408.1"	"463.6"	"407.2"	"658.9"	"34.2"	"8291.7"	"8154.3"	"18220.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05198"	"Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3"	"0.000"	""	"60"	"21"	"48"	"20"	"315"	"36.1"	"5.08"	"8538.67"	"96.78"	"18"	"20"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00575, Pf07541"	"1965"	"ENSG00000134001"	"EIF2S1"	"hsa:1965; P05198"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Translation factors; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; Ebola virus infection in host; Nonalcoholic fatty liver disease; Measles virus infection; Unfolded protein response; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Alzheimer's disease"	"19"	"1"	"343.3"	"233.1"	"358.6"	"331.8"	"321.2"	"349.9"	"710.6"	"32.3"	"14396.5"	"14577.9"	"21632.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UP2"	"Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1"	"0.000"	""	"18"	"19"	"34"	"19"	"1357"	"156.2"	"5.64"	"5781.74"	"96.08"	"11"	"19"	"transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"cytoskeletal activity"	"Pf05104"	"3895"	"ENSG00000126777"	"KTN1"	"B4DZ88; hsa:3895; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86UP2; Q86W57"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle; RHOG GTPase cycle; RND3 GTPase cycle; RHO GTPases activate KTN1"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"11"	"0"	"216.9"	"138.0"	"258.2"	"229.2"	"228.4"	"237.2"	"496.6"	"24.1"	"6443.1"	"6707.7"	"16460.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78371"	"T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4"	"0.000"	""	"28"	"13"	"43"	"13"	"535"	"57.5"	"6.46"	"8829.70"	"95.75"	"9"	"12"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10576"	"ENSG00000166226"	"CCT2"	"A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; hsa:10576; P78371; Q14D36; Q6IAT3"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Neutrophil degranulation; RHOBTB1 GTPase cycle"	"16p11.2 proximal deletion syndrome"	"10"	"0"	"140.6"	"115.7"	"154.4"	"136.1"	"168.2"	"145.3"	"243.4"	"23.2"	"4194.2"	"4448.0"	"12988.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2L1"	"Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2"	"0.000"	""	"28"	"23"	"45"	"23"	"958"	"108.9"	"7.14"	"8284.40"	"95.41"	"18"	"21"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00773, Pf13638, Pf17215, Pf17216, Pf17849"	"22894"	"ENSG00000083520"	"DIS3"	"A6NI21; B2RBL2; hsa:22894; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2; Q9UG36; Q9Y2L1"	"ATF4 activates genes in response to endoplasmic reticulum  stress; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; KSRP (KHSRP) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"466.7"	"363.4"	"514.2"	"455.9"	"457.6"	"417.5"	"803.3"	"35.2"	"8694.6"	"8776.1"	"17290.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68371"	"Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1"	"0.000"	""	"38"	"15"	"41"	"2"	"445"	"49.8"	"4.89"	"7124.37"	"94.42"	"13"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10383"	"ENSG00000188229"	"TUBB4B"	"A2BFA2; hsa:10383; P05217; P68371"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation; COPI-dependent Golgi-to-ER retrograde traffic; Intraflagellar transport; Recycling pathway of L1; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Prefoldin mediated transfer of substrate  to CCT/TriC; Hedgehog 'off' state"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"41"	"15"	"562.8"	"390.1"	"521.8"	"520.2"	"552.3"	"432.7"	"628.5"	"11.5"	"4466.6"	"4717.3"	"9340.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17987"	"T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1"	"0.000"	""	"48"	"20"	"39"	"20"	"556"	"60.3"	"6.11"	"6107.87"	"93.87"	"12"	"20"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00118"	"6950"	"ENSG00000120438"	"TCP1"	"E1P5B2; hsa:6950; P17987; Q15556; Q5TCM3"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"8"	"0"	"211.9"	"175.7"	"265.6"	"214.6"	"248.3"	"224.8"	"428.5"	"36.1"	"5300.4"	"5749.9"	"14219.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30101"	"Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4"	"0.000"	""	"45"	"20"	"40"	"20"	"505"	"56.7"	"6.35"	"6343.46"	"93.27"	"14"	"18"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"2923"	"ENSG00000167004"	"PDIA3"	"hsa:2923; P30101; Q13453; Q14255; Q8IYF8; Q9UMU7"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle"	"Prion disease pathway"	"4"	"0"	"223.9"	"194.4"	"267.1"	"257.7"	"223.9"	"253.4"	"449.8"	"28.4"	"7077.3"	"7927.5"	"19048.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09651"	"Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5"	"0.000"	""	"40"	"16"	"49"	"13"	"372"	"38.7"	"9.13"	"7930.88"	"93.10"	"11"	"13"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11627"	"3178"	"ENSG00000135486"	"HNRNPA1"	"A8K4Z8; hsa:3178; P09651; Q3MIB7; Q6PJZ7"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1-host interactions; SARS-CoV-1 modulates host translation machinery"	"mRNA processing"	"6"	"0"	"1458.2"	"1245.1"	"1383.8"	"1263.3"	"1086.1"	"1201.9"	"3029.8"	"7.4"	"4490.3"	"4535.6"	"7040.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22234"	"Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3"	"0.000"	""	"38"	"18"	"45"	"18"	"425"	"47.0"	"7.23"	"8141.30"	"91.54"	"14"	"16"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00731, Pf01259"	"10606"	"ENSG00000128050"	"PAICS"	"E9PDH9; hsa:10606; P22234; Q68CQ5"	"Purine ribonucleoside monophosphate biosynthesis"	"Metabolic reprogramming in colon cancer"	"2"	"0"	"351.3"	"271.6"	"364.3"	"304.1"	"349.6"	"287.2"	"549.1"	"27.4"	"6274.5"	"6278.4"	"12652.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7KZ85"	"Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2"	"0.000"	""	"19"	"25"	"40"	"25"	"1726"	"198.9"	"4.91"	"5958.57"	"90.54"	"17"	"22"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf14632, Pf14633, Pf14635, Pf14639, Pf14641, Pf17674"	"6830"	"ENSG00000109111"	"SUPT6H"	"A7E2B4; hsa:6830; Q15737; Q6GMQ4; Q7KYW9; Q7KZ85; Q7LDK4; Q8N526; Q92775; Q96AH3; Q9BTH9; Q9BTI2"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	""	"3"	"0"	"1768.3"	"1418.5"	"1788.7"	"1671.2"	"1783.9"	"1341.8"	"2589.4"	"17.4"	"6980.9"	"6743.8"	"11575.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12956"	"X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2"	"0.000"	""	"36"	"19"	"48"	"19"	"609"	"69.8"	"6.64"	"11506.55"	"90.40"	"19"	"16"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf02735, Pf03730, Pf03731"	"2547"	"ENSG00000196419"	"XRCC6"	"B1AHC8; hsa:2547; P12956; Q6FG89; Q9UCQ2; Q9UCQ3"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"Non-homologous end joining; DNA repair pathways, full network; Primary ovarian insufficiency"	"8"	"0"	"890.6"	"696.5"	"969.2"	"827.6"	"900.6"	"790.3"	"2520.5"	"26.6"	"9072.3"	"8912.8"	"14417.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47897"	"Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1"	"0.000"	""	"28"	"19"	"44"	"18"	"775"	"87.7"	"7.15"	"7885.30"	"90.29"	"15"	"19"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00749, Pf03950, Pf04557, Pf04558"	"5859"	"ENSG00000172053"	"QARS1"	"B4DWJ2; hsa:5859; P47897"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"3"	"0"	"339.8"	"210.6"	"423.9"	"344.5"	"368.5"	"347.5"	"586.3"	"25.9"	"4888.3"	"5388.3"	"12725.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60506"	"Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2"	"0.000"	""	"33"	"20"	"46"	"10"	"623"	"69.6"	"8.59"	"8202.83"	"89.53"	"17"	"19"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10492"	"ENSG00000135316"	"SYNCRIP"	"E1P501; E1P502; hsa:10492; O60506; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599; Q96LC1; Q96LC2; Q9Y583"	""	""	"0"	"0"	"671.7"	"552.8"	"687.9"	"626.2"	"528.1"	"638.7"	"1291.1"	"1.1"	"5119.8"	"5396.5"	"9274.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40926"	"Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3"	"0.000"	""	"61"	"18"	"50"	"18"	"338"	"35.5"	"8.68"	"8207.55"	"89.47"	"16"	"17"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4191"	"ENSG00000146701"	"MDH2"	"A8K414; B2RE78; B4DE44; E9PDB2; hsa:4191; O43682; P40926"	"Gluconeogenesis; Citric acid cycle (TCA cycle)"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"8"	"0"	"1355.8"	"1095.4"	"1422.3"	"1289.1"	"1309.1"	"1138.1"	"1665.0"	"25.8"	"11117.4"	"12331.2"	"16212.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11021"	"Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2"	"0.000"	""	"34"	"23"	"51"	"21"	"654"	"72.3"	"5.16"	"10376.15"	"88.61"	"20"	"21"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00012"	"3309"	"ENSG00000044574"	"HSPA5"	"B0QZ61; hsa:3309; P11021; Q2EF78; Q9NPF1; Q9UK02"	"Regulation of HSF1-mediated heat shock response; Platelet degranulation ; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ATF6B (ATF6-beta) activates chaperones; IRE1alpha activates chaperones; PERK regulates gene expression; ATF6 (ATF6-alpha) activates chaperone genes"	"Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Photodynamic therapy-induced unfolded protein response; Prion disease pathway; Unfolded protein response; Orexin receptor pathway"	"14"	"0"	"835.6"	"605.8"	"920.2"	"788.0"	"869.4"	"810.8"	"1286.1"	"22.8"	"9701.3"	"9431.2"	"19783.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14868"	"Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2"	"0.000"	""	"43"	"20"	"45"	"20"	"501"	"57.1"	"6.55"	"8798.32"	"88.02"	"19"	"19"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00152, Pf01336"	"1615"	"ENSG00000115866"	"DARS1"	"A8K3J2; D3DP77; hsa:1615; P14868; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q68CR9; Q9BW52"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Alanine and aspartate metabolism"	"3"	"0"	"231.7"	"181.1"	"254.2"	"224.0"	"227.9"	"237.1"	"553.3"	"66.2"	"10118.9"	"9927.8"	"24135.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52272"	"Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3"	"0.000"	""	"36"	"23"	"50"	"23"	"730"	"77.5"	"8.70"	"7700.65"	"87.94"	"20"	"22"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11532"	"4670"	"ENSG00000099783"	"HNRNPM"	"hsa:4670; P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; FGFR2 alternative splicing"	"mRNA processing"	"4"	"0"	"1121.1"	"851.5"	"1330.3"	"1093.0"	"1249.6"	"1095.1"	"2796.9"	"5.7"	"11084.8"	"11341.2"	"22986.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXJ9"	"N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1"	"0.000"	""	"27"	"25"	"43"	"20"	"866"	"101.2"	"7.42"	"5856.68"	"87.49"	"16"	"23"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf12569, Pf13181"	"80155"	"ENSG00000164134"	"NAA15"	"D3DNY6; hsa:80155; Q52LG9; Q8IWH4; Q8NEV2; Q9BXJ9; Q9H8P6"	""	""	"0"	"5"	"339.9"	"230.7"	"452.8"	"357.0"	"392.6"	"365.7"	"600.9"	"24.7"	"10105.9"	"10804.9"	"25906.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CW1"	"AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2"	"0.000"	""	"43"	"18"	"43"	"18"	"435"	"49.6"	"9.54"	"7889.44"	"86.66"	"13"	"14"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00928, Pf01217"	"1173"	"ENSG00000161203"	"AP2M1"	"A6NE12; D3DNT1; hsa:1173; P20172; P53679; Q96CW1"	"Potential therapeutics for SARS; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Nef mediated downregulation of CD28 cell surface expression; Formation of annular gap junctions"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; GDNF signaling"	"21"	"0"	"256.3"	"163.8"	"336.8"	"292.1"	"327.3"	"322.4"	"1050.5"	"42.4"	"11105.1"	"11354.2"	"18462.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93009"	"Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2"	"0.000"	""	"23"	"17"	"36"	"17"	"1102"	"128.2"	"5.55"	"7047.64"	"86.58"	"12"	"16"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443, Pf00917, Pf12436, Pf14533"	"7874"	"ENSG00000187555"	"USP7"	"A6NMY8; B7Z815; H0Y3G8; hsa:7874; Q93009"	"Ub-specific processing proteases; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Regulation of TP53 Degradation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Regulation of PTEN localization"	"Nucleotide excision repair in xeroderma pigmentosum ; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"10"	"0"	"299.7"	"203.7"	"355.3"	"320.5"	"325.4"	"300.6"	"560.4"	"13.3"	"3408.8"	"3565.7"	"7916.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15311"	"Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4"	"0.000"	""	"40"	"24"	"49"	"13"	"586"	"69.4"	"6.27"	"7372.44"	"86.58"	"20"	"22"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"7430"	"ENSG00000092820"	"EZR"	"E1P5A8; hsa:7430; P15311; P23714; Q4VX75; Q96CU8; Q9NSJ4"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Netrin-1 signaling"	"Pathogenic Escherichia coli infection; AGE/RAGE pathway; VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome; CCL18 signaling pathway; Regulation of actin cytoskeleton; GDNF signaling"	"11"	"0"	"428.2"	"331.3"	"488.8"	"432.2"	"439.6"	"489.0"	"1102.2"	"44.9"	"6535.3"	"6638.3"	"10591.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13885"	"Tubulin beta-2A chain OS=Homo sapiens OX=9606 GN=TUBB2A PE=1 SV=1"	"0.000"	""	"31"	"12"	"37"	"1"	"445"	"49.9"	"4.89"	"6502.96"	"86.35"	"10"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7280"	"ENSG00000137267"	"TUBB2A"	"hsa:7280; Q13885; Q6FGZ8; Q8IWR2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; HCMV Early Events; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; Intraflagellar transport; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; MHC class II antigen presentation; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"34"	"0"	"32.3"	"27.0"	"25.9"	"18.5"	"26.3"	"20.2"	"31.4"	"1.0"	"203.0"	"208.3"	"457.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38159"	"RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3"	"0.000"	""	"41"	"14"	"48"	"5"	"391"	"42.3"	"10.05"	"8772.49"	"85.70"	"12"	"14"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08081"	"27316"	"ENSG00000147274"	"RBMX"	"B4E3U4; D3DWH0; E9PG86; hsa:27316; P38159; Q5JQ67; Q8N8Y7; Q969R3"	"RND2 GTPase cycle; mRNA Splicing - Major Pathway; RND3 GTPase cycle; RND1 GTPase cycle; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"8"	"7"	"1975.3"	"1861.7"	"1922.1"	"1890.3"	"1513.5"	"1852.3"	"4829.4"	"18.3"	"8669.4"	"8752.9"	"13427.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15393"	"Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4"	"0.000"	""	"18"	"18"	"41"	"18"	"1217"	"135.5"	"5.26"	"7495.26"	"85.50"	"16"	"18"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"23450"	"ENSG00000189091"	"SF3B3"	"hsa:23450; Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"469.3"	"308.6"	"511.2"	"440.0"	"492.6"	"338.6"	"955.2"	"17.0"	"5888.7"	"5679.8"	"12876.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60891"	"Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2"	"0.000"	""	"57"	"16"	"38"	"9"	"318"	"34.8"	"6.98"	"6144.79"	"85.37"	"12"	"14"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5631"	"ENSG00000147224"	"PRPS1"	"B1ALA8; B2R6T7; B4DNL6; D3DUX6; hsa:5631; P09329; P60891"	"5-Phosphoribose 1-diphosphate biosynthesis"	""	"1"	"8"	"381.6"	"318.8"	"381.2"	"337.5"	"375.7"	"388.9"	"904.9"	"46.4"	"8062.2"	"8916.1"	"14912.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y450"	"HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1"	"0.000"	""	"30"	"17"	"38"	"17"	"684"	"75.4"	"6.61"	"6707.98"	"85.26"	"13"	"17"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144, Pf08938"	"10767"	"ENSG00000112339"	"HBS1L"	"B7Z365; hsa:10767; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; Q9Y450"	"mRNA decay by 3' to 5' exoribonuclease"	""	"1"	"0"	"243.4"	"170.7"	"250.3"	"237.7"	"270.7"	"352.7"	"1054.5"	"27.3"	"9318.7"	"8902.8"	"13205.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00688"	"Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1"	"0.000"	""	"54"	"18"	"47"	"18"	"224"	"25.2"	"9.28"	"8510.11"	"84.89"	"17"	"17"	""	"nucleus"	"other molecular function"	"Pf00254, Pf18410"	"2287"	"ENSG00000100442"	"FKBP3"	"B2R4Q9; hsa:2287; Q00688; Q14317"	""	""	"0"	"0"	"1344.8"	"1154.0"	"1375.8"	"1365.2"	"1335.2"	"1413.3"	"2388.8"	"28.9"	"12430.7"	"12226.4"	"25764.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19338"	"Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3"	"0.000"	""	"32"	"30"	"59"	"30"	"710"	"76.6"	"4.70"	"9654.46"	"84.77"	"27"	"25"	"developmental processes;other biological processes"	"plasma membrane;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"4691"	"ENSG00000115053"	"NCL"	"hsa:4691; P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"3"	"0"	"3671.3"	"2857.5"	"3529.4"	"3538.0"	"2965.8"	"3130.0"	"5228.3"	"13.0"	"18560.1"	"18212.1"	"32504.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43290"	"U4/U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1"	"0.000"	""	"32"	"20"	"40"	"20"	"800"	"90.2"	"6.13"	"7306.34"	"84.31"	"16"	"18"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03343, Pf19252"	"9092"	"ENSG00000175467"	"SART1"	"A6NDN1; hsa:9092; O43290; Q53GB5"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"828.8"	"587.3"	"740.4"	"700.9"	"668.4"	"675.5"	"1940.9"	"17.0"	"7210.3"	"7089.0"	"15104.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZW5"	"MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6 PE=1 SV=2"	"0.000"	""	"36"	"18"	"41"	"16"	"540"	"61.1"	"6.18"	"6501.27"	"84.25"	"15"	"18"	"cell organization and biogenesis"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"51678"	"ENSG00000105926"	"PALS2"	"A4D157; hsa:51678; Q9H0E1; Q9NZW5"	""	""	"0"	"2"	"421.8"	"314.5"	"432.7"	"414.4"	"444.4"	"394.0"	"636.4"	"18.1"	"8016.7"	"8156.6"	"16072.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35241"	"Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1"	"0.000"	""	"40"	"25"	"48"	"11"	"583"	"68.5"	"6.37"	"7960.92"	"83.89"	"19"	"22"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"5962"	"ENSG00000137710"	"RDX"	"A7YIJ8; A7YIK0; A7YIK3; B7Z9U6; F5H1A7; hsa:5962; P35241; Q86Y61"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"Regulation of actin cytoskeleton"	"4"	"3"	"416.1"	"352.5"	"469.1"	"408.6"	"412.4"	"471.0"	"1090.9"	"40.3"	"8187.2"	"8435.3"	"15045.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75533"	"Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3"	"0.000"	""	"17"	"21"	"45"	"21"	"1304"	"145.7"	"7.09"	"8295.45"	"83.81"	"19"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08920"	"23451"	"ENSG00000115524"	"SF3B1"	"E9PCH3; hsa:23451; O75533"	"mRNA Splicing - Major Pathway; B-WICH complex positively regulates rRNA expression; mRNA Splicing - Minor Pathway"	"mRNA processing; 10q11.21q11.23 copy number variation syndrome"	"5"	"0"	"1439.4"	"1082.1"	"1337.6"	"1325.8"	"1113.4"	"1220.8"	"3218.7"	"12.8"	"8166.6"	"8109.4"	"16268.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06733"	"Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2"	"0.000"	""	"41"	"15"	"35"	"15"	"434"	"47.1"	"7.39"	"5771.43"	"83.42"	"10"	"15"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00113, Pf03952"	"2023"	"ENSG00000074800"	"ENO1"	"B2RD59; hsa:2023; P06733; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5; Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; IL-18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"9"	"0"	"263.5"	"186.0"	"375.3"	"320.5"	"274.6"	"236.0"	"429.0"	"42.4"	"7501.8"	"8182.3"	"14633.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27695"	"DNA-(apurinic or apyrimidinic site) lyase OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2"	"0.000"	""	"56"	"15"	"35"	"15"	"318"	"35.5"	"8.12"	"8595.44"	"83.37"	"13"	"12"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372"	"328"	"ENSG00000100823"	"APEX1"	"hsa:328; P27695; Q969L5; Q99775"	"Displacement of DNA glycosylase by APEX1; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"Thyroid stimulating hormone (TSH) signaling pathway; Spinal cord injury; Base excision repair; DNA repair pathways, full network"	"10"	"0"	"344.1"	"334.9"	"359.6"	"380.0"	"334.7"	"313.5"	"703.5"	"28.8"	"6480.2"	"7028.5"	"12377.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75475"	"PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1"	"0.000"	""	"39"	"18"	"42"	"18"	"530"	"60.1"	"9.13"	"6124.74"	"82.74"	"13"	"17"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf11467"	"11168"	"ENSG00000164985"	"PSIP1"	"D3DRI9; hsa:11168; O00256; O75475; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6"	"Vpr-mediated nuclear import of PICs; Formation of WDR5-containing histone-modifying complexes; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection"	"MECP2 and associated Rett syndrome"	"8"	"0"	"525.3"	"436.8"	"522.3"	"506.9"	"463.0"	"520.4"	"989.4"	"12.2"	"6826.0"	"7027.6"	"15873.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26368"	"Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4"	"0.000"	""	"30"	"12"	"35"	"12"	"475"	"53.5"	"9.09"	"5414.25"	"82.50"	"8"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"11338"	"ENSG00000063244"	"U2AF2"	"hsa:11338; P26368; Q96HC5"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"mRNA processing; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"6"	"0"	"231.3"	"158.1"	"260.2"	"231.9"	"294.6"	"234.5"	"439.8"	"11.3"	"6852.2"	"7222.9"	"11502.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94973"	"AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2"	"0.000"	""	"26"	"20"	"38"	"14"	"939"	"103.9"	"6.96"	"5796.17"	"81.78"	"14"	"19"	"transport"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02296, Pf02883"	"161"	"ENSG00000183020"	"AP2A2"	"hsa:161; O75403; O94973; Q53ET1; Q96SI8"	"Neutrophil degranulation; MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; GABA receptor signaling; mBDNF and proBDNF regulation of GABA neurotransmission"	"17"	"0"	"122.3"	"96.2"	"137.3"	"118.7"	"127.9"	"159.9"	"468.9"	"12.9"	"4281.6"	"4184.4"	"7193.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78527"	"DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3"	"0.000"	""	"6"	"19"	"38"	"19"	"4128"	"468.8"	"7.12"	"7891.57"	"81.55"	"17"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08163, Pf19704, Pf20502"	"5591"	"ENSG00000253729"	"PRKDC"	"hsa:5591; P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6; Q9UME3"	"E3 ubiquitin ligases ubiquitinate target proteins; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); IRF3-mediated induction of type I IFN"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; Non-homologous end joining; Osteoblast differentiation and related diseases; DNA repair pathways, full network; DNA damage response"	"14"	"0"	"357.8"	"276.3"	"357.2"	"347.5"	"360.0"	"343.7"	"532.5"	"19.5"	"4750.6"	"4776.4"	"9727.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMS4"	"Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1"	"0.000"	""	"38"	"12"	"35"	"12"	"504"	"55.1"	"6.61"	"6606.23"	"81.55"	"9"	"12"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04564, Pf08606"	"27339"	"ENSG00000110107"	"PRPF19"	"hsa:27339; Q9UMS4"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	""	"5"	"0"	"221.9"	"150.3"	"216.4"	"178.0"	"187.9"	"186.9"	"426.6"	"20.2"	"7164.0"	"8104.0"	"15159.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28370"	"Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2"	"0.000"	""	"20"	"25"	"45"	"12"	"1054"	"122.5"	"8.09"	"6707.78"	"81.18"	"19"	"25"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"6594"	"ENSG00000102038"	"SMARCA1"	"hsa:6594; P28370; Q5JV41; Q5JV42"	""	"Nuclear receptors meta-pathway; Rett syndrome causing genes"	"2"	"0"	"205.0"	"155.0"	"244.3"	"233.9"	"187.7"	"221.2"	"577.2"	"15.9"	"5013.3"	"4972.7"	"11201.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26358"	"DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2"	"0.000"	""	"15"	"20"	"42"	"20"	"1616"	"183.1"	"7.75"	"7384.61"	"81.14"	"17"	"19"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf01426, Pf02008, Pf06464, Pf12047"	"1786"	"ENSG00000130816"	"DNMT1"	"A0AV63; B7ZLW6; hsa:1786; P26358; Q9UHG5; Q9ULA2; Q9UMZ6"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"Trans-sulfuration pathway; One-carbon metabolism; Retinoblastoma gene in cancer; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"10"	"0"	"332.1"	"276.7"	"360.1"	"330.5"	"337.2"	"342.9"	"805.0"	"10.0"	"6355.1"	"6748.7"	"13898.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05455"	"Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2"	"0.000"	""	"40"	"20"	"44"	"20"	"408"	"46.8"	"7.12"	"8427.42"	"80.89"	"19"	"18"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"6741"	"ENSG00000138385"	"SSB"	"hsa:6741; P05455; Q15367; Q53XJ4"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	""	"2"	"0"	"1486.0"	"1183.7"	"1502.0"	"1355.9"	"1434.4"	"1451.8"	"3808.9"	"33.6"	"13421.9"	"13133.0"	"21158.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17844"	"Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1"	"0.000"	""	"37"	"25"	"49"	"17"	"614"	"69.1"	"8.92"	"8975.28"	"80.50"	"23"	"22"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08061"	"1655"	"ENSG00000108654"	"DDX5"	"B4DLW8; B5BU21; D3DU32; E7ETL9; hsa:1655; O75681; P17844; Q53Y61"	"Estrogen-dependent gene expression; SUMOylation of transcription cofactors; mRNA Splicing - Major Pathway; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"Ciliary landscape"	"6"	"0"	"2138.9"	"1690.1"	"2144.9"	"1893.6"	"1565.1"	"1898.5"	"4261.4"	"2.5"	"8637.3"	"8320.0"	"15179.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68363"	"Tubulin alpha-1B chain OS=Homo sapiens OX=9606 GN=TUBA1B PE=1 SV=1"	"0.000"	""	"42"	"15"	"35"	"3"	"451"	"50.1"	"5.06"	"6002.38"	"80.23"	"11"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10376"	"ENSG00000123416"	"TUBA1B"	"hsa:10376; P04687; P05209; P68363; Q27I68; Q8WU19"	"HCMV Early Events; RHO GTPases Activate Formins; Intraflagellar transport; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state; RHOH GTPase cycle"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Allograft rejection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"35"	"11"	"539.2"	"498.3"	"514.1"	"471.0"	"504.5"	"443.0"	"652.7"	"9.2"	"5801.9"	"6447.4"	"13893.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y383"	"Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2"	"0.000"	""	"35"	"15"	"38"	"11"	"392"	"46.5"	"10.01"	"6876.27"	"80.09"	"12"	"15"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"51631"	"ENSG00000146963"	"LUC7L2"	"B7Z500; hsa:51631; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; Q9Y383"	""	""	"0"	"6"	"271.7"	"201.2"	"307.4"	"303.5"	"267.7"	"279.9"	"621.1"	"21.3"	"8762.6"	"8874.8"	"18106.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08238"	"Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4"	"0.000"	""	"33"	"18"	"33"	"12"	"724"	"83.2"	"5.03"	"5125.15"	"79.91"	"13"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3326"	"ENSG00000096384"	"HSP90AB1"	"B2R5P0; hsa:3326; P08238; Q5T9W7; Q9NQW0; Q9NTK6"	"Regulation of actin dynamics for phagocytic cup formation; Neutrophil degranulation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Aryl hydrocarbon receptor signalling; Estrogen-dependent gene expression; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; Uptake and function of diphtheria toxin"	"Nuclear receptors meta-pathway; NRF2 pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"23"	"6"	"840.3"	"657.2"	"792.2"	"761.3"	"677.8"	"779.8"	"891.5"	"18.9"	"4407.5"	"4198.7"	"8956.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92499"	"ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2"	"0.000"	""	"27"	"15"	"37"	"15"	"740"	"82.4"	"7.23"	"7373.61"	"79.42"	"14"	"15"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00622"	"1653"	"ENSG00000079785"	"DDX1"	"B4DME8; B4DPN6; hsa:1653; Q92499"	"tRNA processing in the nucleus"	"DDX1 as a regulatory component of the Drosha microprocessor; mRNA processing"	"3"	"0"	"569.1"	"436.5"	"584.8"	"529.9"	"546.1"	"433.3"	"1183.6"	"3.5"	"4595.5"	"4615.8"	"9915.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78347"	"General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2"	"0.000"	""	"22"	"20"	"38"	"20"	"998"	"112.3"	"6.39"	"8001.72"	"79.31"	"17"	"18"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02946"	"2969"	"ENSG00000263001"	"GTF2I"	"hsa:2969; O14743; O15359; O43546; O43588; O43589; P78347; Q75M85; Q75M86; Q75M87; Q75M88; Q86U51; Q9BSZ4"	""	"B cell receptor signaling pathway; 7q11.23 copy number variation syndrome; Genetic causes of porto-sinusoidal vascular disease"	"3"	"0"	"604.5"	"486.0"	"673.5"	"567.4"	"636.3"	"538.7"	"1228.1"	"9.3"	"9148.7"	"9333.0"	"19691.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13010"	"X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3"	"0.000"	""	"29"	"20"	"41"	"19"	"732"	"82.7"	"5.81"	"7674.94"	"78.75"	"17"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02735, Pf03730, Pf03731, Pf08785"	"7520"	"ENSG00000079246"	"XRCC5"	"A8K3X5; hsa:7520; P13010; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"Non-homologous end joining; Male infertility; DNA repair pathways, full network; p53 transcriptional gene network"	"9"	"1"	"505.0"	"407.6"	"521.3"	"485.9"	"451.8"	"464.0"	"1191.9"	"23.1"	"6022.7"	"5655.8"	"11616.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20042"	"Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2"	"0.000"	""	"42"	"17"	"39"	"17"	"333"	"38.4"	"5.80"	"5982.22"	"78.52"	"13"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01873"	"8894"	"ENSG00000125977"	"EIF2S2"	"hsa:8894; P20042; Q9BVU0; Q9UJE4"	"ABC-family proteins mediated transport; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP"	"Translation factors; Brain-derived neurotrophic factor (BDNF) signaling pathway; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Primary ovarian insufficiency"	"14"	"0"	"270.7"	"206.6"	"286.8"	"278.4"	"299.3"	"304.7"	"628.7"	"58.6"	"12268.9"	"12218.2"	"17769.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14979"	"Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3"	"0.000"	""	"31"	"14"	"43"	"12"	"420"	"46.4"	"9.57"	"8127.59"	"78.33"	"13"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00076"	"9987"	"ENSG00000152795"	"HNRNPDL"	"hsa:9987; O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	""	"1"	"0"	"953.9"	"887.3"	"898.0"	"908.8"	"764.4"	"618.0"	"2121.4"	"3.4"	"4155.0"	"4027.0"	"6569.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60216"	"Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2"	"0.000"	""	"26"	"14"	"29"	"14"	"631"	"71.6"	"4.65"	"3226.12"	"78.18"	"7"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04824, Pf04825"	"5885"	"ENSG00000164754"	"RAD21"	"A8K0E0; hsa:5885; O60216; Q15001; Q99568"	"Meiotic synapsis; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"13"	"0"	"229.6"	"179.9"	"211.1"	"195.3"	"196.2"	"226.2"	"348.8"	"17.7"	"4056.7"	"4307.4"	"10536.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXP5"	"Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1"	"0.000"	""	"29"	"22"	"39"	"22"	"876"	"100.6"	"5.96"	"6710.32"	"77.46"	"15"	"20"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04959, Pf12066"	"51593"	"ENSG00000087087"	"SRRT"	"A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; hsa:51593; O95808; Q32MI4; Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9BXP5; Q9Y4S4"	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes"	""	"2"	"0"	"999.6"	"768.4"	"1054.1"	"987.2"	"946.0"	"908.3"	"1496.1"	"25.0"	"9463.5"	"9883.2"	"24618.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5S2"	"Serine/threonine-protein kinase MRCK beta OS=Homo sapiens OX=9606 GN=CDC42BPB PE=1 SV=2"	"0.000"	""	"14"	"22"	"37"	"20"	"1711"	"194.2"	"6.37"	"5894.08"	"77.45"	"16"	"18"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00780, Pf08826, Pf15796"	"9578"	"ENSG00000198752"	"CDC42BPB"	"A9JR72; hsa:9578; Q2L7A5; Q86TJ1; Q9ULU5; Q9Y5S2"	"CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"VEGFA-VEGFR2 signaling; 15q11q13 copy number variation"	"5"	"2"	"340.0"	"216.9"	"419.0"	"333.0"	"350.0"	"329.3"	"668.4"	"21.0"	"9342.5"	"9362.6"	"16647.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKV3"	"Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2"	"0.000"	""	"20"	"22"	"41"	"22"	"1341"	"151.8"	"6.43"	"7280.64"	"77.24"	"18"	"17"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf16294"	"22985"	"ENSG00000100813"	"ACIN1"	"B2RTT4; D3DS45; hsa:22985; O75158; Q9UG91; Q9UKV1; Q9UKV2; Q9UKV3"	"mRNA Splicing - Major Pathway; Apoptotic cleavage of cellular proteins"	""	"2"	"0"	"1686.4"	"1266.7"	"1651.8"	"1575.3"	"1410.4"	"1381.7"	"3894.5"	"23.4"	"9269.9"	"9539.8"	"17890.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49792"	"E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2"	"0.000"	""	"8"	"21"	"35"	"14"	"3224"	"358.0"	"6.20"	"5118.77"	"77.01"	"14"	"21"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00160, Pf00638, Pf00641, Pf12185"	"5903"	"ENSG00000153201"	"RANBP2"	"hsa:5903; P49792; Q13074; Q15280; Q53TE2; Q59FH7"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Signaling by ALK fusions and activated point mutants"	""	"35"	"7"	"866.9"	"636.5"	"768.3"	"772.6"	"726.6"	"703.6"	"1050.7"	"3.2"	"6778.3"	"6943.7"	"13387.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB71"	"Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2"	"0.000"	""	"50"	"15"	"43"	"15"	"228"	"26.2"	"8.25"	"8613.94"	"76.88"	"13"	"13"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04969, Pf05002, Pf09032"	"27101"	"ENSG00000116161"	"CACYBP"	"B2ZWH2; B3KSF1; hsa:27101; O60666; Q5R370; Q5R371; Q9HB71"	""	"Gastric cancer network 2"	"1"	"0"	"866.5"	"728.9"	"810.2"	"805.0"	"809.6"	"1111.7"	"3483.1"	"21.9"	"12185.2"	"12399.8"	"21818.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBU9"	"Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1"	"0.000"	""	"24"	"11"	"30"	"11"	"619"	"70.1"	"8.51"	"5325.30"	"76.88"	"10"	"11"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02136, Pf03943, Pf09162"	"10482"	"ENSG00000162231"	"NXF1"	"B4E269; hsa:10482; Q99799; Q9UBU9; Q9UQL2"	"Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"mRNA processing"	"5"	"0"	"286.5"	"232.2"	"322.4"	"295.4"	"281.4"	"290.4"	"1580.1"	"12.0"	"3703.6"	"3560.0"	"6286.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35580"	"Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3"	"0.000"	""	"12"	"18"	"32"	"12"	"1976"	"228.9"	"5.54"	"4995.69"	"76.02"	"11"	"16"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf00612, Pf01576, Pf02736"	"4628"	"ENSG00000133026"	"MYH10"	"B2RWP9; D3DTS1; F8VTL3; hsa:4628; P35580; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16; Q9BWG0"	"EPHA-mediated growth cone collapse; RHO GTPases activate PAKs; RHO GTPases activate CIT; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs"	"Regulation of actin cytoskeleton"	"7"	"1"	"148.9"	"93.6"	"187.0"	"161.5"	"167.3"	"156.6"	"331.4"	"8.7"	"3545.9"	"3523.4"	"9127.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12955"	"Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3 PE=1 SV=3"	"0.000"	""	"5"	"19"	"34"	"16"	"4377"	"480.1"	"6.49"	"6379.56"	"75.90"	"16"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00531, Pf00791, Pf12796, Pf17809"	"288"	"ENSG00000151150"	"ANK3"	"B1AQT2; B4DIL1; E9PE32; hsa:288; Q12955; Q13484; Q5CZH9; Q5VXD5; Q7Z3G4; Q9H0P5"	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	"Splicing factor NOVA regulated synaptic proteins"	"3"	"3"	"738.5"	"557.5"	"548.3"	"590.3"	"531.7"	"523.7"	"907.7"	"13.8"	"5254.7"	"5240.6"	"9207.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95347"	"Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2"	"0.000"	""	"17"	"17"	"36"	"17"	"1197"	"135.6"	"8.43"	"5467.44"	"75.53"	"14"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10592"	"ENSG00000136824"	"SMC2"	"hsa:10592; O95347; Q6IEE0; Q9P1P2"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"Retinoblastoma gene in cancer"	"3"	"0"	"449.2"	"381.2"	"556.1"	"477.3"	"417.4"	"497.6"	"1086.6"	"13.0"	"6216.3"	"6001.2"	"13451.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2W1"	"Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2"	"0.000"	""	"22"	"21"	"46"	"20"	"955"	"108.6"	"10.15"	"8224.97"	"75.34"	"21"	"18"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9967"	"ENSG00000054118"	"THRAP3"	"D3DPS5; hsa:9967; Q5VTK6; Q9Y2W1"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"Interactome of polycomb repressive complex 2 (PRC2)"	"3"	"1"	"1506.5"	"1101.2"	"1289.5"	"1350.1"	"1109.2"	"1202.7"	"2573.8"	"15.3"	"8054.6"	"8272.8"	"16726.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15046"	"Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3"	"0.000"	""	"29"	"16"	"31"	"16"	"597"	"68.0"	"6.35"	"4177.50"	"75.06"	"10"	"16"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"3735"	"ENSG00000065427"	"KARS1"	"A8MSK1; D3DUK4; hsa:3735; O14946; Q15046; Q96J25; Q9HB23"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"3"	"0"	"243.3"	"186.1"	"290.7"	"247.9"	"256.7"	"207.0"	"530.0"	"27.5"	"8842.3"	"9146.6"	"20720.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GS9"	"U4/U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2"	"0.000"	""	"34"	"17"	"32"	"17"	"565"	"65.3"	"8.91"	"4628.37"	"74.65"	"10"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00443, Pf02148"	"10713"	"ENSG00000168883"	"USP39"	"A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; hsa:10713; Q53GS9; Q6NX47; Q96RK9; Q9BV89; Q9H381; Q9P050; Q9Y310"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"252.7"	"157.6"	"262.1"	"231.2"	"285.5"	"242.3"	"573.8"	"24.4"	"3756.1"	"4010.9"	"8844.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49756"	"RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3"	"0.000"	""	"23"	"18"	"34"	"18"	"843"	"100.1"	"6.32"	"5873.93"	"74.40"	"13"	"18"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf01480"	"58517"	"ENSG00000119707"	"RBM25"	"A0PJL9; B2RNA8; B3KT03; hsa:58517; P49756; Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"249.0"	"177.1"	"245.0"	"231.6"	"202.2"	"244.1"	"477.3"	"20.2"	"4635.9"	"5013.2"	"11717.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15459"	"Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1"	"0.000"	""	"28"	"16"	"32"	"16"	"793"	"88.8"	"5.22"	"5901.89"	"74.39"	"12"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00240, Pf01805, Pf12230"	"10291"	"ENSG00000099995"	"SF3A1"	"E9PAW1; hsa:10291; Q15459"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"381.9"	"312.1"	"363.2"	"375.6"	"378.6"	"352.9"	"570.1"	"21.4"	"4736.8"	"5110.6"	"9736.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40939"	"Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2"	"0.000"	""	"28"	"17"	"35"	"17"	"763"	"82.9"	"9.04"	"6310.83"	"73.76"	"15"	"17"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"3030"	"ENSG00000084754"	"HADHA"	"B2R7L4; B4DYP2; hsa:3030; P40939; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Mitochondrial fatty acid oxidation disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"13"	"0"	"341.6"	"275.8"	"387.0"	"342.1"	"395.0"	"330.6"	"676.4"	"14.3"	"6369.3"	"6217.0"	"14392.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35637"	"RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1"	"0.000"	""	"21"	"12"	"33"	"8"	"526"	"53.4"	"9.36"	"5244.73"	"73.17"	"8"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"2521"	"ENSG00000089280"	"FUS"	"hsa:2521; P35637; Q9H4A8"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"MECP2 and associated Rett syndrome; mRNA processing"	"4"	"4"	"1448.0"	"1149.1"	"1264.4"	"1080.6"	"1059.6"	"1159.5"	"2645.3"	"23.2"	"7142.5"	"7355.3"	"10887.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99729"	"Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2"	"0.000"	""	"32"	"14"	"49"	"12"	"332"	"36.2"	"8.21"	"8146.86"	"73.00"	"13"	"13"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3182"	"ENSG00000197451"	"HNRNPAB"	"B3KNN5; D3DWP7; hsa:3182; Q04150; Q8N7U3; Q99729; Q9BQ99"	""	"Pre-implantation embryo; mRNA processing"	"2"	"0"	"1492.2"	"1486.1"	"1476.8"	"1440.4"	"1378.9"	"1337.8"	"3561.3"	"27.9"	"6533.7"	"6729.8"	"10140.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR30"	"Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5"	"0.000"	""	"23"	"15"	"33"	"14"	"783"	"87.3"	"9.28"	"6171.10"	"72.95"	"15"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08152"	"9188"	"ENSG00000165732"	"DDX21"	"B2RDL0; hsa:9188; Q13436; Q5VX41; Q68D35; Q9NR30"	"Major pathway of rRNA processing in the nucleolus and cytosol; B-WICH complex positively regulates rRNA expression"	"10q11.21q11.23 copy number variation syndrome"	"3"	"1"	"424.5"	"311.8"	"457.8"	"412.9"	"397.6"	"388.1"	"975.1"	"8.6"	"5069.5"	"5009.4"	"10231.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14839"	"Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2"	"0.000"	""	"13"	"18"	"32"	"13"	"1912"	"217.9"	"5.86"	"5939.00"	"71.93"	"13"	"17"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"1108"	"ENSG00000111642"	"CHD4"	"hsa:1108; Q14839; Q8IXZ5"	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Regulation of TP53 Activity through Acetylation; NGF-stimulated transcription"	"Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"9"	"5"	"265.0"	"212.3"	"256.5"	"263.0"	"266.3"	"264.3"	"406.3"	"13.8"	"5008.2"	"5260.3"	"14003.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23246"	"Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2"	"0.000"	""	"29"	"18"	"37"	"17"	"707"	"76.1"	"9.44"	"6692.83"	"71.75"	"16"	"16"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"6421"	"ENSG00000116560"	"SFPQ"	"hsa:6421; P23246; P30808; Q5SZ71"	"Suppression of apoptosis; PTK6 Regulates Proteins Involved in RNA Processing"	"mRNA processing; Type 2 papillary renal cell carcinoma"	"4"	"1"	"1824.3"	"1470.8"	"1642.4"	"1555.5"	"1383.0"	"1642.9"	"4145.3"	"10.4"	"8738.7"	"8550.9"	"13835.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAF3"	"WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1"	"0.000"	""	"31"	"15"	"32"	"15"	"677"	"76.2"	"7.03"	"5142.53"	"71.37"	"12"	"15"	"DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf11816"	"57599"	"ENSG00000114742"	"WDR48"	"B4DM86; B4DQI2; B4DY84; hsa:57599; Q63HJ2; Q658Y1; Q8N3Z1; Q8TAF3; Q9NSK8; Q9P279"	"Ub-specific processing proteases; Fanconi Anemia Pathway; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins; Recognition of DNA damage by PCNA-containing replication complex"	"DNA repair pathways, full network"	"5"	"0"	"172.8"	"116.7"	"181.5"	"163.1"	"179.5"	"198.5"	"412.0"	"15.6"	"4021.4"	"4034.6"	"7096.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50991"	"T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4"	"0.000"	""	"40"	"15"	"30"	"15"	"539"	"57.9"	"7.83"	"4971.56"	"71.36"	"9"	"14"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00118"	"10575"	"ENSG00000115484"	"CCT4"	"B2R6I3; B7Z8B1; F5H5W3; hsa:10575; O14870; P50991; Q53QP9; Q96C51"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"246.9"	"209.6"	"279.2"	"246.5"	"241.3"	"255.7"	"452.8"	"25.7"	"4217.3"	"4589.4"	"11783.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10567"	"AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2"	"0.000"	""	"20"	"19"	"37"	"7"	"949"	"104.6"	"5.06"	"6359.64"	"71.33"	"14"	"16"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"123.1"	"101.4"	"101.0"	"101.8"	"130.6"	"126.8"	"314.7"	"4.0"	"3572.3"	"3540.5"	"6682.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11387"	"DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2"	"0.000"	""	"29"	"18"	"38"	"18"	"765"	"90.7"	"9.31"	"5593.29"	"71.31"	"13"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf01028, Pf02919, Pf14370"	"7150"	"ENSG00000198900"	"TOP1"	"A8KA78; E1P5W3; hsa:7150; O43256; P11387; Q12855; Q12856; Q15610; Q5TFY3; Q9UJN0"	"SUMOylation of DNA replication proteins"	"Ebola virus infection in host; 15q25 copy number variation"	"3"	"0"	"361.1"	"275.6"	"390.4"	"336.1"	"327.8"	"360.1"	"997.1"	"32.7"	"9361.0"	"9257.3"	"20749.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39748"	"Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1"	"0.000"	""	"43"	"14"	"30"	"14"	"380"	"42.6"	"8.62"	"5273.96"	"71.25"	"10"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"2237"	"ENSG00000168496"	"FEN1"	"hsa:2237; P39748"	"HDR through MMEJ (alt-NHEJ); Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand"	"Base excision repair; DNA repair pathways, full network"	"8"	"0"	"491.4"	"421.0"	"561.7"	"514.0"	"467.3"	"518.5"	"798.8"	"27.5"	"6702.6"	"6890.3"	"15704.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2TAY7"	"WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2"	"0.000"	""	"27"	"14"	"34"	"14"	"513"	"57.5"	"7.18"	"5572.51"	"70.20"	"9"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf17814"	"55234"	"ENSG00000122692"	"SMU1"	"B4E3L0; hsa:55234; Q2TAY7; Q9BU59; Q9HA96; Q9NVD1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"294.9"	"238.4"	"293.0"	"267.1"	"287.3"	"316.2"	"655.7"	"28.8"	"5929.3"	"6186.6"	"14530.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50990"	"T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4"	"0.000"	""	"36"	"17"	"32"	"17"	"548"	"59.6"	"5.60"	"5646.91"	"69.93"	"12"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10694"	"ENSG00000156261"	"CCT8"	"A6NN54; B4DEM7; B4DQH4; hsa:10694; P50990; Q4VBP8"	"Neutrophil degranulation; Association of TriC/CCT with target proteins during biosynthesis; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"8"	"0"	"237.9"	"186.8"	"301.1"	"253.4"	"255.4"	"227.8"	"411.3"	"19.7"	"5420.2"	"5595.0"	"15624.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43243"	"Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2"	"0.000"	""	"22"	"22"	"39"	"22"	"847"	"94.6"	"6.25"	"7219.96"	"69.22"	"19"	"18"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	""	"9782"	"ENSG00000015479"	"MATR3"	"B7ZAV5; D3DQC3; hsa:9782; P43243; Q9UHW0; Q9UQ27"	""	""	"0"	"0"	"2320.2"	"1689.9"	"2214.8"	"2109.8"	"1735.1"	"1858.5"	"3140.8"	"12.6"	"8574.9"	"8425.2"	"16831.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13523"	"Serine/threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3"	"0.000"	""	"18"	"16"	"32"	"15"	"1007"	"116.9"	"10.26"	"5893.80"	"69.18"	"12"	"15"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8899"	"ENSG00000112739"	"PRPF4B"	"A8K5C9; hsa:8899; Q13523; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"1"	"537.8"	"371.5"	"551.1"	"489.9"	"466.9"	"504.1"	"1448.6"	"9.2"	"6365.2"	"6644.6"	"13685.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94832"	"Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2"	"0.000"	""	"16"	"15"	"34"	"15"	"1006"	"116.1"	"9.39"	"6198.91"	"68.69"	"13"	"14"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4642"	"ENSG00000176658"	"MYO1D"	"A6H8V3; hsa:4642; O94832; Q8NHP9"	""	""	"0"	"0"	"220.2"	"158.4"	"244.1"	"185.4"	"207.1"	"221.0"	"571.0"	"28.3"	"8222.1"	"8180.5"	"17681.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41252"	"Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2"	"0.000"	""	"15"	"16"	"33"	"16"	"1262"	"144.4"	"6.15"	"6789.58"	"68.05"	"12"	"15"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf08264, Pf19302"	"3376"	"ENSG00000196305"	"IARS1"	"A8KAE9; hsa:3376; P41252; Q5TCD0; Q7Z3T4; Q9H588"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Amino acid metabolism"	"3"	"0"	"232.3"	"159.1"	"262.4"	"242.6"	"244.6"	"236.9"	"391.5"	"32.7"	"6566.2"	"6780.0"	"17360.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71U36"	"Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1"	"0.000"	""	"38"	"13"	"29"	"1"	"451"	"50.1"	"5.06"	"4759.42"	"68.00"	"9"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7846"	"ENSG00000167552"	"TUBA1A"	"A8K0B8; G3V1U9; hsa:7846; P04687; P05209; Q71U36"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; The role of GTSE1 in G2/M progression after G2 checkpoint; Recycling pathway of L1; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of mitotic centrosome proteins and complexes; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; HCMV Early Events; COPI-mediated anterograde transport; Intraflagellar transport; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Recruitment of NuMA to mitotic centrosomes; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Hedgehog 'off' state"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease; PAFAH1B1 copy number variation"	"41"	"0"	"6.9"	"6.8"	"9.7"	"7.8"	"10.4"	"6.1"	"9.7"	"0.0"	"118.4"	"110.8"	"350.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSL3"	"Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11 PE=1 SV=2"	"0.000"	""	"11"	"18"	"39"	"18"	"2073"	"237.5"	"7.74"	"8131.37"	"67.61"	"17"	"17"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"139818"	"ENSG00000147251"	"DOCK11"	"A6NMF0; hsa:139818; Q5JSL3; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3"	"Factors involved in megakaryocyte development and platelet production; CDC42 GTPase cycle; RAC1 GTPase cycle"	""	"3"	"0"	"283.1"	"234.5"	"359.6"	"303.7"	"314.4"	"446.8"	"1402.2"	"42.7"	"8884.0"	"8641.3"	"11660.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ35"	"Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2"	"0.000"	""	"9"	"16"	"32"	"16"	"2752"	"299.4"	"12.06"	"4935.08"	"67.15"	"13"	"16"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08312"	"23524"	"ENSG00000167978"	"SRRM2"	"A6NKB9; D3DU97; hsa:23524; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40; Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ35; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"762.9"	"586.3"	"788.4"	"763.4"	"659.4"	"678.5"	"1501.9"	"7.3"	"4900.2"	"4864.9"	"10166.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00291"	"Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5"	"0.000"	""	"20"	"19"	"32"	"19"	"1037"	"116.1"	"5.30"	"5447.55"	"66.37"	"15"	"17"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"3092"	"ENSG00000127946"	"HIP1"	"B4E3I7; E7ES17; hsa:3092; O00291; O00328; Q2TB58; Q8TDL4; V5LU97"	"Clathrin-mediated endocytosis; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"DYRK1A involvement regarding cell proliferation in brain development; 5q35 copy number variation"	"5"	"0"	"201.9"	"142.2"	"253.2"	"213.8"	"252.3"	"222.5"	"403.7"	"33.2"	"6508.5"	"6518.7"	"12666.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04075"	"Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2"	"0.000"	""	"54"	"18"	"36"	"14"	"364"	"39.4"	"8.09"	"7724.99"	"66.27"	"15"	"14"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"226"	"ENSG00000149925"	"ALDOA"	"B4DXI7; hsa:226; P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2"	"Glycolysis; Gluconeogenesis; Neutrophil degranulation; Platelet degranulation"	"VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; 16p11.2 proximal deletion syndrome; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"4"	"1637.8"	"1282.1"	"1471.0"	"1407.1"	"1461.4"	"1199.2"	"2369.2"	"9.8"	"10795.4"	"11006.6"	"20326.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15233"	"Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4"	"0.000"	""	"32"	"16"	"36"	"15"	"471"	"54.2"	"8.95"	"6199.88"	"65.88"	"14"	"15"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"4841"	"ENSG00000147140"	"NONO"	"B7Z4C2; D3DVV4; F5GYZ3; hsa:4841; O00201; P30807; Q12786; Q15233; Q9BQC5"	""	"mRNA processing"	"1"	"0"	"1948.0"	"1302.2"	"2031.3"	"1786.1"	"1713.8"	"1801.1"	"3661.0"	"12.0"	"9211.2"	"8746.4"	"17450.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L014"	"Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2"	"0.000"	""	"19"	"17"	"35"	"17"	"1031"	"117.3"	"9.29"	"5894.93"	"65.85"	"14"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"9879"	"ENSG00000145833"	"DDX46"	"hsa:9879; O94894; Q7L014; Q96EI0; Q9Y658"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"427.6"	"328.2"	"468.1"	"438.8"	"415.6"	"429.2"	"740.1"	"19.8"	"6907.3"	"7266.1"	"15287.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04264"	"Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6"	"0.000"	""	"26"	"14"	"34"	"12"	"644"	"66.0"	"8.12"	"5404.30"	"65.61"	"12"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038, Pf16208, Pf16210"	"3848"	"ENSG00000167768"	"KRT1"	"B2RA01; hsa:3848; P04264; P85925; P86104; Q14720; Q6GSJ0; Q9H298"	"Formation of the cornified envelope; Neutrophil degranulation"	"Corticotropin-releasing hormone signaling pathway"	"4"	"2"	"688.7"	"1176.4"	"767.4"	"1539.5"	"660.5"	"5276.8"	"2278.6"	"17.3"	"3509.2"	"4155.0"	"6760.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35240"	"Merlin OS=Homo sapiens OX=9606 GN=NF2 PE=1 SV=1"	"0.000"	""	"27"	"16"	"34"	"16"	"595"	"69.6"	"6.47"	"6115.11"	"65.48"	"13"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4771"	"ENSG00000186575"	"NF2"	"hsa:4771; O95683; P35240; Q8WUJ2; Q969N0; Q969Q3; Q96T30; Q96T31; Q96T32; Q96T33; Q9BTW3; Q9UNG9; Q9UNH3; Q9UNH4"	"Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate PAKs"	"Ectoderm differentiation; Ectoderm differentiation; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; 3q29 copy number variation syndrome; Pleural mesothelioma"	"10"	"0"	"536.8"	"350.0"	"481.9"	"409.8"	"500.0"	"447.4"	"695.1"	"12.8"	"8579.2"	"8464.7"	"15946.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P258"	"Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2"	"0.000"	""	"27"	"15"	"34"	"15"	"522"	"56.0"	"8.78"	"6246.00"	"65.46"	"14"	"13"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00415"	"55920"	"ENSG00000179051; ENSG00000281540"	"RCC2"	"hsa:55920; Q8IVL9; Q9BSN6; Q9NPV8; Q9P258"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"498.3"	"405.7"	"517.2"	"484.5"	"429.7"	"509.8"	"1305.4"	"16.1"	"9316.2"	"9754.7"	"19706.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86XP3"	"ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1"	"0.000"	""	"25"	"19"	"32"	"19"	"938"	"102.9"	"7.02"	"6204.83"	"65.38"	"15"	"16"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11325"	"ENSG00000198231"	"DDX42"	"A6NML1; A8KA43; hsa:11325; O75619; Q68G51; Q86XP3; Q96BK1; Q96HR7; Q9Y3V8"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"0"	"681.0"	"584.5"	"655.5"	"629.9"	"615.0"	"616.9"	"1757.1"	"7.1"	"4918.4"	"4814.9"	"8382.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYA6"	"Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1"	"0.000"	""	"32"	"16"	"32"	"16"	"563"	"65.1"	"5.05"	"6222.43"	"65.13"	"12"	"14"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08216"	"56259"	"ENSG00000132792"	"CTNNBL1"	"B4DE16; hsa:56259; Q0VAL9; Q0VAM0; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q8WYA6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"256.6"	"195.1"	"283.3"	"262.1"	"247.0"	"229.5"	"478.8"	"13.5"	"6180.2"	"6328.8"	"15397.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10809"	"60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2"	"0.000"	""	"34"	"18"	"29"	"18"	"573"	"61.0"	"5.87"	"4102.23"	"64.97"	"10"	"17"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00118"	"3329"	"ENSG00000144381"	"HSPD1"	"B2R5M6; B7Z712; hsa:3329; P10809; Q38L19; Q9UCR6"	"Mitochondrial protein import; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; 8p23.1 copy number variation syndrome; Sudden infant death syndrome (SIDS) susceptibility pathways"	"5"	"0"	"767.6"	"527.7"	"782.8"	"712.1"	"709.5"	"672.9"	"907.6"	"24.7"	"5296.5"	"5245.9"	"15972.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96E39"	"RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1"	"0.000"	""	"34"	"12"	"34"	"3"	"390"	"42.1"	"9.89"	"5830.79"	"64.92"	"10"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf08081"	"494115"	"ENSG00000213516"	"RBMXL1"	"hsa:494115; Q96E39"	""	""	"0"	"0"	"225.8"	"192.8"	"252.7"	"222.9"	"199.7"	"215.0"	"519.1"	"7.0"	"1095.1"	"1079.8"	"1847.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2J5"	"Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2"	"0.000"	""	"16"	"17"	"33"	"17"	"1176"	"134.4"	"7.30"	"5350.40"	"64.70"	"11"	"14"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00133, Pf08264"	"51520"	"ENSG00000133706"	"LARS1"	"A2RRR4; A7E266; B4DJ10; hsa:51520; Q2TU79; Q9NSE1; Q9P2J5"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	""	"2"	"0"	"293.0"	"221.7"	"282.6"	"254.3"	"270.9"	"261.8"	"432.0"	"22.5"	"5311.5"	"5466.6"	"14017.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUQ8"	"Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3"	"0.000"	""	"21"	"16"	"35"	"16"	"820"	"95.5"	"9.55"	"5550.74"	"64.29"	"14"	"15"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"9416"	"ENSG00000174243"	"DDX23"	"B2R600; B4DH15; hsa:9416; O43188; Q9BUQ8"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"0"	"576.2"	"426.6"	"589.1"	"529.4"	"505.5"	"506.8"	"1336.1"	"8.2"	"5945.5"	"5850.7"	"14134.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14204"	"Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5"	"0.000"	""	"6"	"19"	"29"	"19"	"4646"	"532.1"	"6.40"	"4170.89"	"64.24"	"11"	"18"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf18198, Pf18199"	"1778"	"ENSG00000197102"	"DYNC1H1"	"B0I1R0; hsa:1778; Q14204; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5"	"Separation of Sister Chromatids; Neutrophil degranulation; MHC class II antigen presentation; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; PAFAH1B1 copy number variation"	"23"	"0"	"233.2"	"167.5"	"229.1"	"244.0"	"221.7"	"272.5"	"374.2"	"9.6"	"3036.2"	"3256.8"	"6321.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31948"	"Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1"	"0.000"	""	"29"	"14"	"30"	"14"	"543"	"62.6"	"6.80"	"4890.51"	"64.05"	"10"	"14"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf17830"	"10963"	"ENSG00000168439"	"STIP1"	"B4DM70; F5H0T1; G3XAD8; hsa:10963; P31948; Q3ZCU9; Q5TZU9"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RND1 GTPase cycle"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"305.9"	"258.1"	"355.0"	"344.0"	"331.5"	"350.9"	"635.8"	"24.1"	"6668.4"	"7217.3"	"17881.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2NL82"	"Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1"	"0.000"	""	"27"	"15"	"30"	"15"	"804"	"91.8"	"7.42"	"5557.90"	"63.79"	"12"	"15"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"55720"	"ENSG00000167721"	"TSR1"	"hsa:55720; Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"185.2"	"151.9"	"213.4"	"191.5"	"193.7"	"213.4"	"524.6"	"13.4"	"3618.3"	"3697.1"	"7319.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NC51"	"Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2"	"0.000"	""	"44"	"17"	"29"	"17"	"408"	"44.9"	"8.65"	"5820.50"	"63.71"	"12"	"14"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"26135"	"ENSG00000142864"	"SERBP1"	"hsa:26135; Q5VU19; Q5VU20; Q5VU22; Q8NC51; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4; Q9Y367; Q9Y4S3"	""	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	"1"	"0"	"1764.2"	"1290.9"	"1635.7"	"1584.1"	"1550.8"	"1704.3"	"4656.5"	"9.6"	"8920.4"	"8461.4"	"16643.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55795"	"Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1"	"0.000"	""	"28"	"11"	"33"	"4"	"449"	"49.2"	"6.30"	"5787.72"	"63.27"	"10"	"10"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00076, Pf08080"	"3188"	"ENSG00000126945"	"HNRNPH2"	"A1L400; hsa:3188; P55795; Q9HHA7"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"0"	"138.5"	"96.9"	"139.2"	"123.8"	"128.3"	"135.7"	"239.1"	"8.2"	"1810.8"	"1716.4"	"3602.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Y6"	"DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2"	"0.000"	""	"16"	"14"	"35"	"14"	"1135"	"128.1"	"7.83"	"6906.60"	"63.22"	"13"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf06883"	"84172"	"ENSG00000125630"	"POLR1B"	"B7Z6Y7; B7Z823; F5GZX4; F8W898; hsa:84172; Q2TAM4; Q585T5; Q6ZRR2; Q9H9D3; Q9H9Y6"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"0"	"190.4"	"129.5"	"210.9"	"185.0"	"181.5"	"207.2"	"476.1"	"39.3"	"5760.5"	"5445.9"	"10525.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYF8"	"Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2"	"0.000"	""	"14"	"14"	"33"	"13"	"920"	"106.1"	"9.98"	"5675.39"	"63.02"	"12"	"14"	"stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9774"	"ENSG00000029363"	"BCLAF1"	"A2RU75; B7ZM58; E1P586; hsa:9774; Q14673; Q86WU6; Q86WY0; Q9NYF8"	""	"Interactome of polycomb repressive complex 2 (PRC2)"	"1"	"0"	"1685.4"	"1226.2"	"1534.9"	"1460.0"	"1280.9"	"1481.2"	"2872.5"	"2.5"	"8906.1"	"8929.0"	"18830.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13573"	"SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1"	"0.000"	""	"33"	"16"	"32"	"16"	"536"	"61.5"	"9.52"	"5854.71"	"62.13"	"14"	"15"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf02731"	"22938"	"ENSG00000100603"	"SNW1"	"A8K8A9; hsa:22938; Q13483; Q13573; Q32N03; Q5D0D6"	"mRNA Splicing - Major Pathway; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"Novel intracellular components of RIG-I-like receptor pathway; Splicing factor NOVA regulated synaptic proteins; Notch signaling pathway"	"15"	"0"	"908.2"	"822.5"	"826.3"	"812.0"	"724.4"	"819.4"	"2031.3"	"14.7"	"6639.7"	"6708.3"	"11968.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05639"	"Elongation factor 1-alpha 2 OS=Homo sapiens OX=9606 GN=EEF1A2 PE=1 SV=1"	"0.000"	""	"40"	"12"	"29"	"4"	"463"	"50.4"	"9.03"	"4230.88"	"62.10"	"8"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1917"	"ENSG00000101210"	"EEF1A2"	"B5BUF3; E1P5J1; hsa:1917; P54266; Q05639; Q0VGC7"	"Eukaryotic Translation Elongation"	"Translation factors"	"2"	"0"	"43.2"	"35.2"	"51.6"	"37.8"	"35.4"	"39.8"	"108.9"	"1.1"	"876.0"	"910.3"	"1833.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92945"	"Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4"	"0.000"	""	"30"	"18"	"33"	"15"	"711"	"73.1"	"7.30"	"5645.82"	"62.10"	"15"	"18"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf09005"	"8570"	"ENSG00000088247"	"KHSRP"	"hsa:8570; O00301; Q59EZ9; Q5U4P6; Q92945; Q9UNT5; Q9UQH5"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"Pre-implantation embryo"	"3"	"3"	"1133.2"	"897.3"	"1151.5"	"1093.7"	"895.6"	"1167.4"	"2353.6"	"3.0"	"6893.5"	"6819.9"	"10840.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60231"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2"	"0.000"	""	"17"	"16"	"32"	"15"	"1041"	"119.2"	"6.80"	"5464.85"	"62.09"	"10"	"14"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"8449"	"ENSG00000204560; ENSG00000206486; ENSG00000226171; ENSG00000231377; ENSG00000233049; ENSG00000233418; ENSG00000233561"	"DHX16"	"hsa:8449; O60231; O60322; Q5JP45; Q969X7; Q96QC1"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"1"	"333.7"	"229.8"	"348.7"	"318.7"	"301.2"	"337.3"	"597.3"	"27.2"	"5222.6"	"5265.8"	"12253.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EK5"	"KIF-binding protein OS=Homo sapiens OX=9606 GN=KIFBP PE=1 SV=1"	"0.000"	""	"26"	"14"	"30"	"14"	"621"	"71.8"	"5.49"	"7246.79"	"61.67"	"13"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;mitochondrion"	"cytoskeletal activity"	"Pf12309"	"26128"	"ENSG00000198954"	"KIFBP"	"A8K5M8; hsa:26128; Q96EK5; Q9BR89; Q9ULE1; Q9Y428"	""	""	"0"	"0"	"153.6"	"121.0"	"196.5"	"185.0"	"181.7"	"227.0"	"708.9"	"36.8"	"11454.3"	"11394.4"	"15480.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q1KMD3"	"Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1"	"0.000"	""	"20"	"12"	"26"	"12"	"747"	"85.1"	"4.91"	"4054.91"	"61.64"	"10"	"12"	""	"nucleus;other cell component"	""	"Pf00622, Pf02037, Pf13671"	"221092"	"ENSG00000214753"	"HNRNPUL2"	"hsa:221092; Q1KMD3; Q8N3B3"	""	""	"0"	"0"	"481.6"	"396.5"	"485.1"	"502.6"	"454.8"	"421.0"	"1007.5"	"38.9"	"3516.9"	"3238.6"	"5735.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12081"	"Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2"	"0.000"	""	"43"	"19"	"30"	"14"	"509"	"57.4"	"5.88"	"4785.82"	"61.60"	"11"	"18"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf03129, Pf13393"	"3035"	"ENSG00000170445"	"HARS1"	"B4DHQ1; B4DY73; D6REN6; hsa:3035; J3KNE5; P12081"	"Cytosolic tRNA aminoacylation"	"Allograft rejection"	"2"	"5"	"378.9"	"284.7"	"406.1"	"365.7"	"302.0"	"368.7"	"787.6"	"24.2"	"7680.3"	"7779.0"	"18269.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTJ3"	"Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2"	"0.000"	""	"16"	"18"	"31"	"18"	"1288"	"147.1"	"6.79"	"5478.27"	"61.32"	"14"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10051"	"ENSG00000113810"	"SMC4"	"A6NLT9; D3DNL8; hsa:10051; O95752; Q8NDL4; Q9NTJ3; Q9UNT9"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"Ciliary landscape"	"3"	"0"	"637.3"	"522.6"	"694.8"	"632.4"	"591.9"	"653.2"	"1419.1"	"16.4"	"6731.9"	"6457.2"	"12869.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y490"	"Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3"	"0.000"	""	"7"	"14"	"22"	"14"	"2541"	"269.6"	"6.07"	"2987.18"	"61.09"	"6"	"14"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00373, Pf01608, Pf08913, Pf09141, Pf16511"	"7094"	"ENSG00000137076"	"TLN1"	"A6NMY0; hsa:7094; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; Q9Y490"	"Platelet degranulation ; Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; TROP2 regulatory signaling"	"18"	"0"	"280.7"	"239.2"	"293.3"	"293.2"	"271.3"	"274.4"	"525.6"	"26.6"	"4070.8"	"4241.1"	"9864.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15144"	"Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1"	"0.000"	""	"55"	"12"	"22"	"12"	"300"	"34.3"	"7.36"	"2414.24"	"60.70"	"5"	"12"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf04045"	"10109"	"ENSG00000163466"	"ARPC2"	"hsa:10109; O15144; Q92801; Q9P1D4"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"181.2"	"169.7"	"240.2"	"222.8"	"219.7"	"180.1"	"359.2"	"12.6"	"6568.0"	"6725.4"	"14902.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14966"	"Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2"	"0.000"	""	"10"	"17"	"28"	"17"	"1978"	"220.5"	"6.38"	"5223.22"	"60.66"	"12"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf12171"	"27332"	"ENSG00000075292"	"ZNF638"	"A0A096LPH6; B5MDV1; B7ZLD1; hsa:27332; Q14966; Q53R34; Q5XJ05; Q68DP3; Q6P2H2; Q7Z3T7; Q8NF92; Q8TCA1; Q9H2G1; Q9NP37"	"Transcriptional regulation of white adipocyte differentiation"	""	"1"	"0"	"465.2"	"391.8"	"512.0"	"473.0"	"429.6"	"486.3"	"1170.8"	"18.7"	"7670.0"	"7316.4"	"16741.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82979"	"SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3"	"0.000"	""	"41"	"11"	"31"	"11"	"210"	"23.7"	"6.42"	"5587.74"	"60.35"	"8"	"11"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037"	"84324"	"ENSG00000205323"	"SARNP"	"A8K393; hsa:84324; P82979; Q9P066"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"3"	"0"	"638.1"	"539.4"	"598.3"	"560.4"	"495.5"	"547.3"	"1162.0"	"48.5"	"9386.3"	"9712.8"	"15020.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H307"	"Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5"	"0.000"	""	"25"	"15"	"32"	"15"	"717"	"81.6"	"7.14"	"5615.44"	"59.43"	"13"	"12"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04696, Pf04697"	"5411"	"ENSG00000100941"	"PNN"	"B4DZX8; hsa:5411; O60899; Q53EM7; Q6P5X4; Q7KYL1; Q99738; Q9H307; Q9UHZ9; Q9UQR9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"992.4"	"727.6"	"894.9"	"890.4"	"760.9"	"859.1"	"2121.7"	"16.5"	"5979.4"	"5594.2"	"11408.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB6"	"LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1"	"0.000"	""	"23"	"15"	"28"	"15"	"759"	"85.2"	"6.84"	"4340.31"	"59.25"	"10"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"51474"	"ENSG00000050405"	"LIMA1"	"B2RB09; hsa:51474; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96; Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5; Q9UHB6"	""	""	"0"	"0"	"568.7"	"440.6"	"528.0"	"538.0"	"499.5"	"518.0"	"1126.7"	"9.2"	"7238.9"	"7034.3"	"12382.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02790"	"Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3"	"0.000"	""	"36"	"11"	"21"	"11"	"459"	"51.8"	"5.43"	"3506.40"	"59.17"	"5"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254, Pf00515"	"2288"	"ENSG00000004478"	"FKBP4"	"D3DUQ1; hsa:2288; Q02790; Q9UCP1; Q9UCV7"	"Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Estrogen-dependent gene expression; Attenuation phase"	"Androgen receptor signaling pathway"	"6"	"0"	"77.9"	"63.9"	"101.8"	"87.9"	"117.2"	"88.9"	"171.9"	"6.8"	"2912.3"	"3106.2"	"10429.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62316"	"Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1"	"0.000"	""	"74"	"10"	"36"	"10"	"118"	"13.5"	"9.91"	"8042.30"	"58.83"	"9"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf01423"	"6633"	"ENSG00000125743"	"SNRPD2"	"A8K797; hsa:6633; J3KPM5; P43330; P62316"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"mRNA processing"	"5"	"0"	"1211.6"	"702.0"	"1324.5"	"1157.5"	"1059.7"	"956.1"	"1517.4"	"6.3"	"3466.2"	"3190.9"	"7102.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12874"	"Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1"	"0.000"	""	"30"	"12"	"21"	"12"	"501"	"58.8"	"5.38"	"3636.49"	"58.77"	"7"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11931, Pf12108, Pf13297, Pf16837"	"10946"	"ENSG00000183431"	"SF3A3"	"D3DPT5; hsa:10946; Q12874; Q15460; Q5VT87"	"mRNA Splicing - Major Pathway"	"Exercise-induced circadian regulation; mRNA processing"	"3"	"0"	"304.3"	"195.0"	"279.0"	"229.2"	"255.9"	"262.6"	"413.9"	"14.6"	"4861.4"	"4800.3"	"10531.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11908"	"Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2"	"0.000"	""	"36"	"10"	"22"	"3"	"318"	"34.7"	"6.61"	"3135.62"	"58.31"	"7"	"10"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5634"	"ENSG00000101911"	"PRPS2"	"hsa:5634; P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7"	"5-Phosphoribose 1-diphosphate biosynthesis"	""	"1"	"0"	"181.4"	"137.1"	"178.5"	"160.7"	"187.9"	"189.9"	"332.1"	"4.7"	"1740.6"	"1544.7"	"3228.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15042"	"U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2"	"0.000"	""	"19"	"16"	"33"	"15"	"1029"	"118.2"	"8.47"	"5917.77"	"57.75"	"14"	"13"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076, Pf01805, Pf04818, Pf08312"	"23350"	"ENSG00000163714"	"U2SURP"	"A0PJ60; hsa:23350; O15042; Q0D2M1; Q2NKQ7; Q9BR70"	"mRNA Splicing - Major Pathway"	""	"1"	"1"	"960.6"	"709.0"	"857.3"	"864.9"	"804.6"	"835.1"	"1309.3"	"12.7"	"7213.8"	"7130.5"	"14981.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AE4"	"Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3"	"0.000"	""	"21"	"15"	"35"	"10"	"644"	"67.5"	"7.61"	"6204.11"	"57.71"	"15"	"15"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013, Pf09005"	"8880"	"ENSG00000162613"	"FUBP1"	"hsa:8880; Q12828; Q96AE4"	""	""	"0"	"2"	"471.8"	"431.2"	"486.3"	"481.3"	"439.9"	"504.5"	"1134.2"	"7.3"	"3771.8"	"3682.1"	"5684.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94826"	"Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1"	"0.000"	""	"26"	"13"	"28"	"13"	"608"	"67.4"	"7.12"	"4890.53"	"57.70"	"11"	"13"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00515, Pf13181"	"9868"	"ENSG00000154174"	"TOMM70"	"D3DN48; hsa:9868; O94826"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Mitochondrial protein import; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; PINK1-PRKN Mediated Mitophagy"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"9"	"0"	"284.3"	"193.8"	"319.8"	"274.2"	"278.6"	"236.7"	"447.9"	"4.0"	"5484.2"	"5652.4"	"11310.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P99999"	"Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2"	"0.000"	""	"67"	"12"	"33"	"12"	"105"	"11.7"	"9.57"	"6608.57"	"57.57"	"11"	"9"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00034"	"54205"	"ENSG00000172115"	"CYCS"	"A4D166; B2R4I1; hsa:54205; P00001; P99999; Q6NUR2; Q6NX69; Q96BV4"	"Respiratory electron transport; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria; Pyroptosis"	"miRNA regulation of DNA damage response; Apoptosis modulation and signaling; Alzheimer's disease and miRNA effects; AGE/RAGE pathway; Parkinson's disease pathway; Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Oxidative damage response; NO/cGMP/PKG mediated neuroprotection; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Pleural mesothelioma; Complement system in neuronal development and plasticity; Alzheimer's disease; DNA damage response"	"36"	"0"	"825.9"	"1443.9"	"1529.3"	"1134.8"	"787.1"	"1547.0"	"6140.9"	"8.6"	"8561.6"	"8751.2"	"11377.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTI5"	"Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1"	"0.000"	""	"15"	"15"	"23"	"13"	"1447"	"164.6"	"8.47"	"2355.88"	"57.55"	"5"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf20168"	"23047"	"ENSG00000083642"	"PDS5B"	"hsa:23047; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9NTI5; Q9Y2I5; Q9Y451"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"6"	"2"	"227.2"	"185.0"	"218.0"	"221.5"	"222.6"	"216.3"	"516.1"	"12.9"	"4456.8"	"4837.1"	"10343.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75937"	"DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2"	"0.000"	""	"50"	"12"	"23"	"12"	"253"	"29.8"	"9.06"	"3503.94"	"57.35"	"8"	"11"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226"	"22826"	"ENSG00000126698; ENSG00000285317"	"DNAJC8"	"B4DUU4; D3DPM0; hsa:22826; O75937; Q6IBA4; Q8N4Z5; Q9P051; Q9P067"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"693.2"	"442.5"	"694.5"	"714.2"	"580.1"	"693.1"	"1168.3"	"16.3"	"7290.2"	"6848.2"	"15435.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULC4"	"Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1"	"0.000"	""	"68"	"9"	"24"	"9"	"181"	"20.5"	"8.82"	"4960.72"	"57.30"	"7"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf01472, Pf17832"	"28985"	"ENSG00000232119; ENSG00000288295"	"MCTS1"	"B4DGY2; hsa:28985; Q502X6; Q9ULC4"	""	""	"0"	"0"	"80.4"	"49.9"	"107.7"	"90.9"	"97.3"	"83.9"	"193.1"	"12.1"	"5095.8"	"5342.4"	"10082.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06830"	"Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1"	"0.000"	""	"63"	"15"	"34"	"14"	"199"	"22.1"	"8.13"	"6030.45"	"57.17"	"12"	"13"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"5052"	"ENSG00000117450"	"PRDX1"	"B5BU26; D3DPZ8; hsa:5052; P35703; Q06830; Q2V576; Q5T154; Q5T155"	"Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; NFE2L2 regulating anti-oxidant/detoxification enzymes; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Androgen receptor signaling pathway; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway"	"8"	"1"	"719.1"	"589.2"	"805.3"	"533.7"	"653.8"	"650.7"	"1495.4"	"7.1"	"8587.5"	"8379.0"	"18748.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T2T1"	"MAGUK p55 subfamily member 7 OS=Homo sapiens OX=9606 GN=MPP7 PE=1 SV=1"	"0.000"	""	"31"	"13"	"25"	"13"	"576"	"65.5"	"7.14"	"5948.31"	"57.16"	"11"	"11"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf02828"	"143098"	"ENSG00000150054"	"MPP7"	"B2RCC9; B4DWL9; B5MDZ3; D3DRW3; hsa:143098; Q5T2T0; Q5T2T1; Q8IY28"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RHOJ GTPase cycle"	""	"6"	"0"	"169.8"	"139.4"	"180.2"	"167.7"	"190.0"	"175.1"	"437.7"	"12.6"	"3999.4"	"3831.6"	"8663.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49368"	"T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4"	"0.000"	""	"41"	"19"	"30"	"19"	"545"	"60.5"	"6.49"	"5864.39"	"56.94"	"13"	"14"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"7203"	"ENSG00000163468"	"CCT3"	"A6NE14; hsa:7203; P49368; Q5SZY1; Q9BR64"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"230.6"	"160.7"	"266.6"	"215.8"	"233.4"	"227.3"	"442.1"	"16.1"	"6196.9"	"6803.0"	"18348.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54886"	"Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2"	"0.000"	""	"27"	"17"	"30"	"17"	"795"	"87.2"	"7.12"	"5110.36"	"56.92"	"14"	"16"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00171, Pf00696"	"5832"	"ENSG00000059573"	"ALDH18A1"	"B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; hsa:5832; O95952; P54886; Q3KQU2; Q5T566; Q5T567; Q9UM72"	""	"Amino acid metabolism"	"1"	"0"	"273.1"	"198.7"	"298.6"	"247.2"	"286.3"	"263.5"	"508.1"	"20.1"	"4190.3"	"4227.4"	"9363.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92576"	"PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3"	"0.000"	""	"10"	"13"	"20"	"12"	"2039"	"229.3"	"6.96"	"2220.84"	"56.89"	"6"	"13"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"23469"	"ENSG00000118482"	"PHF3"	"A3KFI8; hsa:23469; Q14CR5; Q5CZI1; Q5T1T6; Q92576; Q9NQ16; Q9UI45"	""	""	"0"	"1"	"205.4"	"189.9"	"253.5"	"236.4"	"256.5"	"258.0"	"504.5"	"6.6"	"3727.0"	"3802.4"	"8860.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62805"	"Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2"	"0.000"	""	"61"	"10"	"30"	"10"	"103"	"11.4"	"11.36"	"6219.38"	"56.80"	"10"	"9"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511"	"121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370"	"ENSG00000158406; ENSG00000197061; ENSG00000197238; ENSG00000197837; ENSG00000270276; ENSG00000270882; ENSG00000273542; ENSG00000274618; ENSG00000275126; ENSG00000276180; ENSG00000276966; ENSG00000277157; ENSG00000278637; ENSG00000278705"	"H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"	"A2VCL0; hsa:121504; hsa:554313; hsa:8294; hsa:8359; hsa:8360; hsa:8361; hsa:8362; hsa:8363; hsa:8364; hsa:8365; hsa:8366; hsa:8367; hsa:8368; hsa:8370; P02304; P02305; P62805; Q6DRA9; Q6FGB8; Q6NWP7"	"Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Meiotic synapsis; Estrogen-dependent gene expression; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Meiotic recombination; SUMOylation of chromatin organization proteins; HCMV Late Events; Amyloid fiber formation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"Gastric cancer network 1; Histone modifications; 22q11.2 copy number variation syndrome; Male infertility; Type II interferon signaling"	"50"	"0"	"296.0"	"223.8"	"298.6"	"231.7"	"238.7"	"280.5"	"1650.3"	"11.7"	"3770.8"	"3681.0"	"5603.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5X1"	"Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1"	"0.000"	""	"31"	"14"	"28"	"14"	"595"	"66.6"	"5.58"	"6276.38"	"56.76"	"13"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00018, Pf00787, Pf10456"	"51429"	"ENSG00000130340"	"SNX9"	"hsa:51429; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20; Q9Y5X1"	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	""	"2"	"0"	"167.0"	"129.1"	"207.2"	"206.2"	"262.9"	"431.1"	"1345.4"	"17.3"	"8091.7"	"7923.7"	"10517.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY44"	"Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3"	"0.000"	""	"30"	"13"	"24"	"13"	"585"	"64.9"	"8.87"	"4311.91"	"56.34"	"8"	"12"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf08662"	"83939"	"ENSG00000144895"	"EIF2A"	"A8MPS6; B4DF96; B4DQ14; D3DNI9; hsa:83939; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; Q9BY44"	""	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"3"	"0"	"415.2"	"299.5"	"395.4"	"414.7"	"366.3"	"385.3"	"764.4"	"4.5"	"4890.1"	"4786.8"	"11141.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11940"	"Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2"	"0.000"	""	"25"	"14"	"33"	"10"	"636"	"70.6"	"9.50"	"5459.57"	"55.87"	"14"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"26986"	"ENSG00000070756"	"PABPC1"	"hsa:26986; P11940; Q15097; Q93004"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Deadenylation of mRNA"	"Translation factors; Endoderm differentiation; VEGFA-VEGFR2 signaling; Acute viral myocarditis"	"11"	"3"	"901.8"	"738.8"	"872.2"	"766.1"	"766.8"	"807.0"	"1806.5"	"6.4"	"5214.8"	"5292.9"	"9730.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60709"	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	"0.000"	""	"30"	"11"	"27"	"3"	"375"	"41.7"	"5.48"	"5045.56"	"55.80"	"10"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"60"	"ENSG00000075624"	"ACTB"	"hsa:60; P02570; P60709; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; HATs acetylate histones; B-WICH complex positively regulates rRNA expression; UCH proteinases; Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; RHO GTPases Activate Formins; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHO GTPases Activate WASPs and WAVEs; RHO GTPases activate IQGAPs; RHOF GTPase cycle; Clathrin-mediated endocytosis; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; EPH-ephrin mediated repulsion of cells; Interaction between L1 and Ankyrins; Prefoldin mediated transfer of substrate  to CCT/TriC; Adherens junctions interactions; DNA Damage Recognition in GG-NER; Formation of annular gap junctions; Folding of actin by CCT/TriC; Cell-extracellular matrix interactions"	"Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; Ebola virus infection in host; Acute viral myocarditis; Thermogenesis; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Regulation of actin cytoskeleton; Network map of SARS-CoV-2 signaling pathway"	"47"	"11"	"449.8"	"397.8"	"609.4"	"492.9"	"350.0"	"417.7"	"992.5"	"4.9"	"5836.5"	"6402.3"	"10215.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55265"	"Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4"	"0.000"	""	"11"	"12"	"28"	"12"	"1226"	"136.0"	"8.65"	"5056.34"	"55.71"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf02137, Pf02295"	"103"	"ENSG00000160710"	"ADAR"	"B1AQQ9; B1AQR0; D3DV76; hsa:103; O15223; O43859; O43860; P55265; Q9BYM3; Q9BYM4"	"Interferon alpha/beta signaling; C6 deamination of adenosine; Formation of editosomes by ADAR proteins"	"Measles virus infection; Cytosolic DNA-sensing pathway"	"5"	"0"	"470.5"	"418.3"	"555.3"	"498.8"	"465.3"	"480.8"	"997.6"	"4.5"	"5395.8"	"5366.7"	"11138.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13123"	"Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3"	"0.000"	""	"25"	"17"	"30"	"17"	"557"	"65.6"	"6.64"	"4883.94"	"55.52"	"14"	"15"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07807, Pf07808"	"3550"	"ENSG00000113141"	"IK"	"hsa:3550; Q13123; Q6IPD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"807.7"	"668.0"	"745.6"	"735.8"	"676.0"	"749.3"	"1593.6"	"21.3"	"7092.6"	"7152.7"	"15245.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25705"	"ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1"	"0.000"	""	"25"	"12"	"26"	"12"	"553"	"59.7"	"9.13"	"4585.60"	"55.51"	"9"	"12"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf00306, Pf02874"	"498"	"ENSG00000152234"	"ATP5F1A"	"A8K092; B4DY56; hsa:498; K7ENP3; P25705; Q53XX6; Q8IXV2; Q96FB4; Q96HW2; Q96IR6; Q9BTV8"	"Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"6"	"0"	"222.0"	"181.0"	"275.0"	"221.1"	"281.1"	"292.0"	"514.7"	"14.5"	"5369.1"	"5478.2"	"11067.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96N67"	"Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4"	"0.000"	""	"9"	"17"	"28"	"17"	"2140"	"242.4"	"6.80"	"5098.75"	"55.50"	"14"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"85440"	"ENSG00000116641"	"DOCK7"	"hsa:85440; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32; Q8TB82; Q96N67; Q96NG6; Q96NI0; Q9C092"	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production; MET activates RAP1 and RAC1"	""	"4"	"0"	"702.4"	"495.1"	"580.7"	"637.3"	"569.6"	"598.2"	"990.1"	"10.2"	"5399.7"	"5580.5"	"11013.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50570"	"Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2"	"0.000"	""	"16"	"11"	"25"	"9"	"870"	"98.0"	"7.44"	"4105.83"	"55.11"	"8"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"1785"	"ENSG00000079805"	"DNM2"	"A8K1B6; E7EV30; E9PEQ4; hsa:1785; K7ESI9; P50570; Q5I0Y0; Q7Z5S3; Q9UPH4"	"Recycling pathway of L1; MHC class II antigen presentation; Clathrin-mediated endocytosis; Lysosome Vesicle Biogenesis; NGF-stimulated transcription; Golgi Associated Vesicle Biogenesis; Toll Like Receptor 4 (TLR4) Cascade; NOSTRIN mediated eNOS trafficking; Retrograde neurotrophin signalling; Formation of annular gap junctions"	"Synaptic vesicle pathway; Fragile X syndrome; Intracellular trafficking proteins involved in CMT neuropathy"	"14"	"3"	"218.1"	"133.7"	"281.0"	"247.9"	"241.1"	"236.2"	"555.1"	"8.5"	"3933.0"	"4005.0"	"8431.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75131"	"Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1"	"0.000"	""	"22"	"9"	"20"	"8"	"537"	"60.1"	"5.85"	"2031.62"	"54.96"	"5"	"9"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00168, Pf07002"	"8895"	"ENSG00000085719"	"CPNE3"	"A8KA47; hsa:8895; O75131; Q8IYA1"	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	""	"2"	"0"	"87.6"	"73.4"	"144.2"	"115.0"	"135.7"	"100.6"	"215.9"	"13.9"	"2237.9"	"2323.7"	"12174.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62701"	"40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2"	"0.000"	""	"46"	"15"	"33"	"15"	"263"	"29.6"	"10.15"	"5094.15"	"54.95"	"14"	"14"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf00900, Pf01479, Pf08071, Pf16121"	"6191"	"ENSG00000198034"	"RPS4X"	"hsa:6191; P12631; P12750; P27576; P55831; P62701; Q14727; Q6IPY4"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"894.1"	"783.0"	"984.2"	"827.1"	"876.3"	"835.5"	"2450.0"	"16.0"	"8252.6"	"8895.4"	"15778.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43684"	"Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1"	"0.000"	""	"35"	"11"	"28"	"11"	"328"	"37.1"	"6.84"	"5736.17"	"54.92"	"11"	"10"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"9184"	"ENSG00000154473"	"BUB3"	"A6NJ42; B2R6E7; D3DRE9; hsa:9184; O43684; O43685"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"12"	"0"	"492.5"	"350.1"	"499.8"	"504.7"	"432.9"	"432.6"	"769.5"	"3.5"	"7146.4"	"7262.3"	"15958.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHX1"	"Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1"	"0.000"	""	"29"	"16"	"23"	"16"	"559"	"59.8"	"5.29"	"3154.86"	"54.40"	"8"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"22827"	"ENSG00000179950; ENSG00000274081"	"PUF60"	"A8K8K8; hsa:22827; Q969E7; Q96D94; Q96H63; Q99628; Q9NZA0; Q9UHX1; Q9UJY7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"470.2"	"318.2"	"475.0"	"419.3"	"410.2"	"402.8"	"785.6"	"17.8"	"7177.6"	"7306.0"	"17273.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NU22"	"Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2"	"0.000"	""	"3"	"16"	"30"	"16"	"5596"	"632.4"	"5.68"	"5693.20"	"54.39"	"14"	"14"	"cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07728, Pf17865, Pf17867"	"23195"	"ENSG00000112159; ENSG00000288121"	"MDN1"	"hsa:23195; O15019; Q5T794; Q9NU22"	""	""	"0"	"0"	"177.1"	"124.1"	"196.8"	"157.2"	"187.7"	"169.6"	"277.1"	"14.9"	"3202.2"	"3262.4"	"7229.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16152"	"Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3"	"0.000"	""	"44"	"10"	"26"	"10"	"277"	"30.4"	"8.32"	"5016.47"	"54.35"	"9"	"10"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00106"	"873"	"ENSG00000159228"	"CBR1"	"B2RBZ7; B4DFK7; hsa:873; P16152; Q3LHW8"	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"	"Nuclear receptors meta-pathway; NRF2 pathway; Prostaglandin synthesis and regulation"	"4"	"0"	"138.9"	"110.3"	"167.0"	"145.3"	"164.2"	"146.3"	"310.5"	"5.2"	"4019.8"	"4119.3"	"8783.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92878"	"DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1"	"0.000"	""	"11"	"13"	"22"	"12"	"1312"	"153.8"	"6.89"	"3039.86"	"53.80"	"8"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04423, Pf13476, Pf13558"	"10111"	"ENSG00000113522"	"RAD50"	"B9EGF5; hsa:10111; O43254; Q6GMT7; Q6P5X3; Q92878; Q9UP86"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Resolution of D-loop Structures through Holliday Junction Intermediates; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"29"	"1"	"593.3"	"389.7"	"700.4"	"573.2"	"499.1"	"505.1"	"1078.2"	"32.5"	"5667.9"	"5610.0"	"11718.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04637"	"Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4"	"0.000"	""	"8"	"12"	"27"	"12"	"1599"	"175.4"	"5.33"	"5237.75"	"53.77"	"11"	"10"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02020, Pf02847, Pf02854"	"1981"	"ENSG00000114867"	"EIF4G1"	"D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; hsa:1981; O43177; O95066; Q04637; Q5HYG0; Q6ZN21; Q8N102"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Deadenylation of mRNA; mTORC1-mediated signalling"	"Translation factors; VEGFA-VEGFR2 signaling; Acute viral myocarditis; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Pleural mesothelioma"	"18"	"0"	"424.3"	"336.7"	"422.2"	"417.7"	"368.1"	"442.4"	"909.0"	"9.9"	"4336.9"	"4375.9"	"9366.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX58"	"Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2"	"0.000"	""	"31"	"11"	"22"	"11"	"379"	"43.6"	"9.54"	"4425.97"	"53.76"	"7"	"10"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"189.7"	"141.8"	"228.1"	"211.2"	"197.4"	"219.8"	"682.4"	"12.2"	"6133.4"	"5869.4"	"11915.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27816"	"Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3"	"0.000"	""	"18"	"16"	"30"	"16"	"1152"	"120.9"	"5.43"	"6190.47"	"53.71"	"14"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00418"	"4134"	"ENSG00000047849"	"MAP4"	"hsa:4134; P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9"	""	"Splicing factor NOVA regulated synaptic proteins; 2q37 copy number variation syndrome"	"2"	"0"	"912.6"	"658.4"	"886.3"	"829.9"	"684.4"	"872.3"	"2667.6"	"19.4"	"5875.8"	"5921.3"	"12243.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52597"	"Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3"	"0.000"	""	"30"	"13"	"29"	"10"	"415"	"45.6"	"5.58"	"4081.77"	"53.65"	"10"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf08080"	"3185"	"ENSG00000169813"	"HNRNPF"	"B3KM84; hsa:3185; P52597; Q5T0N2; Q96AU2"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"MECP2 and associated Rett syndrome"	"5"	"0"	"1138.7"	"871.6"	"747.8"	"759.7"	"762.1"	"923.6"	"1249.1"	"4.8"	"5402.6"	"5241.1"	"8726.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53582"	"Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2"	"0.000"	""	"42"	"11"	"15"	"11"	"386"	"43.2"	"7.17"	"1815.32"	"53.54"	"4"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf15801"	"23173"	"ENSG00000164024"	"METAP1"	"B4E2E6; hsa:23173; P53582"	"Inactivation, recovery and regulation of the phototransduction cascade"	""	"1"	"0"	"182.4"	"146.5"	"188.4"	"163.2"	"175.0"	"104.1"	"388.2"	"12.2"	"3196.5"	"3095.0"	"6531.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96P16"	"Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1"	"0.000"	""	"41"	"11"	"27"	"9"	"312"	"35.7"	"7.55"	"5422.91"	"53.13"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"55197"	"ENSG00000141425"	"RPRD1A"	"A8KA42; B2RBA3; hsa:55197; Q7Z5G8; Q96FY9; Q96P16; Q9NVL4"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"2"	"239.1"	"179.6"	"291.5"	"231.7"	"276.3"	"266.1"	"731.2"	"13.8"	"5375.6"	"5265.0"	"11298.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14498"	"RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2"	"0.000"	""	"23"	"11"	"27"	"9"	"530"	"59.3"	"10.10"	"3615.49"	"53.13"	"9"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf15519"	"9584"	"ENSG00000131051"	"RBM39"	"A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; hsa:9584; Q14498; Q14499"	"mRNA Splicing - Major Pathway"	"VEGFA-VEGFR2 signaling; mRNA processing"	"3"	"1"	"348.6"	"257.4"	"348.1"	"274.6"	"301.0"	"289.3"	"658.2"	"10.8"	"2988.7"	"3109.8"	"6417.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30876"	"DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1"	"0.000"	""	"14"	"14"	"26"	"14"	"1174"	"133.8"	"6.87"	"4988.69"	"53.05"	"12"	"14"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"5431"	"ENSG00000047315"	"POLR2B"	"A8K1A8; hsa:5431; P30876; Q8IZ61"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"709.5"	"592.7"	"692.6"	"656.4"	"656.7"	"580.8"	"1215.1"	"18.1"	"4083.8"	"4009.8"	"7584.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43143"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2"	"0.000"	""	"19"	"12"	"24"	"11"	"795"	"90.9"	"7.46"	"3776.92"	"52.99"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"1665"	"ENSG00000109606"	"DHX15"	"hsa:1665; O43143; Q9NQT7"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"120.6"	"99.4"	"185.7"	"134.3"	"175.2"	"149.0"	"344.8"	"17.4"	"2932.2"	"3101.4"	"7199.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92917"	"G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2"	"0.000"	""	"29"	"11"	"25"	"11"	"476"	"52.2"	"6.15"	"4777.85"	"52.96"	"8"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00467, Pf12656"	"27238"	"ENSG00000068394"	"GPKOW"	"hsa:27238; Q59EK5; Q92917; Q9BQA8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"237.6"	"182.5"	"262.1"	"262.4"	"236.2"	"257.8"	"541.5"	"9.2"	"4254.8"	"4255.1"	"7700.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVJ6"	"U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1"	"0.000"	""	"18"	"11"	"26"	"11"	"771"	"87.9"	"7.87"	"5196.80"	"52.93"	"10"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"10813"	"ENSG00000156697"	"UTP14A"	"A8K7A3; A8MVQ1; B4DQ08; E9PEL7; hsa:10813; Q5JYF1; Q9BVJ6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"454.2"	"296.9"	"379.6"	"385.9"	"407.8"	"399.4"	"743.2"	"20.9"	"3869.6"	"3732.2"	"7804.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12905"	"Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2"	"0.000"	""	"33"	"10"	"19"	"10"	"390"	"43.0"	"5.26"	"3597.40"	"52.87"	"7"	"8"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07528"	"3608"	"ENSG00000143621"	"ILF2"	"A6NDB0; B2R8G7; hsa:3608; Q12905; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0"	"Neutrophil degranulation"	"B cell receptor signaling pathway"	"2"	"0"	"698.2"	"613.4"	"727.2"	"671.4"	"585.3"	"720.8"	"1878.7"	"3.4"	"4599.0"	"4936.2"	"9051.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96I24"	"Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2"	"0.000"	""	"21"	"12"	"32"	"10"	"572"	"61.6"	"8.38"	"4855.04"	"52.46"	"11"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"8939"	"ENSG00000107164"	"FUBP3"	"A3KFK8; A3KFL0; hsa:8939; Q92946; Q96I24; Q9BVB6"	""	""	"0"	"0"	"763.1"	"688.8"	"696.9"	"631.1"	"625.3"	"721.8"	"1432.3"	"5.6"	"4694.1"	"4695.2"	"7334.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VP6"	"Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2"	"0.000"	""	"13"	"12"	"24"	"12"	"1230"	"136.3"	"5.78"	"4705.04"	"52.38"	"10"	"12"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08623"	"55832"	"ENSG00000111530"	"CAND1"	"B2RAU3; hsa:55832; O94918; Q6PIY4; Q86VP6; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85"	"Neutrophil degranulation; Neddylation; Iron uptake and transport"	"Endoderm differentiation"	"4"	"0"	"186.0"	"157.7"	"265.5"	"206.3"	"204.4"	"221.1"	"441.3"	"21.3"	"5666.4"	"5666.1"	"9921.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15428"	"Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2"	"0.000"	""	"17"	"8"	"23"	"8"	"464"	"49.2"	"9.64"	"4890.19"	"52.35"	"5"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf12874, Pf16835"	"8175"	"ENSG00000104897"	"SF3A2"	"B2RBU1; D6W605; hsa:8175; O75245; Q15428"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"265.8"	"215.1"	"255.2"	"241.1"	"210.8"	"276.3"	"502.9"	"15.3"	"4965.5"	"4999.5"	"10985.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67809"	"Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3"	"0.000"	""	"33"	"7"	"21"	"5"	"324"	"35.9"	"9.88"	"3244.41"	"52.24"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00313"	"4904"	"ENSG00000065978"	"YBX1"	"hsa:4904; P16990; P16991; P67809; Q14972; Q15325; Q5FVF0"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Interferon gamma signaling; mRNA Splicing - Minor Pathway; Noncanonical activation of NOTCH3"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; MECP2 and associated Rett syndrome; mRNA processing; Sudden infant death syndrome (SIDS) susceptibility pathways"	"10"	"2"	"372.5"	"329.2"	"263.8"	"274.3"	"241.5"	"337.2"	"907.8"	"3.3"	"1308.9"	"1371.0"	"1874.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46777"	"60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3"	"0.000"	""	"35"	"12"	"31"	"12"	"297"	"34.3"	"9.72"	"5965.96"	"52.05"	"12"	"10"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf14204, Pf17144"	"6125"	"ENSG00000122406"	"RPL5"	"hsa:6125; P46777; Q32LZ3; Q53HH6; Q9H3F4"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"753.6"	"603.3"	"750.6"	"705.1"	"635.5"	"714.4"	"3219.3"	"7.6"	"7653.9"	"7263.0"	"12492.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99832"	"T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2"	"0.000"	""	"35"	"13"	"17"	"13"	"543"	"59.3"	"7.65"	"1875.68"	"51.96"	"5"	"11"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"10574"	"ENSG00000135624"	"CCT7"	"A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; hsa:10574; O14871; Q6FI26; Q99832"	"Formation of tubulin folding intermediates by CCT/TriC; RHOBTB1 GTPase cycle; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome"	"9"	"0"	"97.3"	"65.2"	"107.1"	"92.8"	"76.5"	"74.8"	"196.2"	"19.2"	"3185.1"	"3499.1"	"9762.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DI7"	"U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1"	"0.000"	""	"44"	"11"	"22"	"11"	"357"	"39.3"	"8.10"	"3677.22"	"51.81"	"7"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"9410"	"ENSG00000060688"	"SNRNP40"	"B4DQJ1; hsa:9410; O75938; O95320; Q96DI7"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"411.4"	"317.0"	"372.2"	"372.1"	"369.8"	"367.5"	"898.8"	"9.7"	"4829.7"	"4977.1"	"10317.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36578"	"60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5"	"0.000"	""	"37"	"15"	"32"	"14"	"427"	"47.7"	"11.06"	"6040.11"	"51.81"	"14"	"12"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00573, Pf14374"	"6124"	"ENSG00000174444"	"RPL4"	"A8K502; hsa:6124; P36578; P39029; Q4VBR0; Q969Z9"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"1"	"938.9"	"817.7"	"934.8"	"855.4"	"766.7"	"887.7"	"3743.3"	"10.1"	"9182.6"	"9443.5"	"15620.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UDY2"	"Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2"	"0.000"	""	"11"	"12"	"22"	"12"	"1190"	"133.9"	"7.40"	"4314.57"	"51.73"	"10"	"11"	"cell adhesion;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00595, Pf00625, Pf07653"	"9414"	"ENSG00000119139"	"TJP2"	"A2A3H9; B7Z2R8; B7Z7T6; F5H301; F5H886; hsa:9414; Q15883; Q5VXL0; Q5VXL1; Q8N756; Q8NI14; Q99839; Q9UDY0; Q9UDY1; Q9UDY2"	"Signaling by Hippo; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"1q21.1 copy number variation syndrome; 15q11q13 copy number variation"	"7"	"0"	"183.5"	"122.3"	"206.8"	"163.7"	"208.9"	"178.3"	"332.7"	"7.2"	"3858.4"	"4000.9"	"9386.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49591"	"Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3"	"0.000"	""	"33"	"15"	"22"	"15"	"514"	"58.7"	"6.43"	"3882.95"	"51.71"	"9"	"12"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02403"	"6301"	"ENSG00000031698"	"SARS1"	"B2R6Y9; hsa:6301; P49591; Q5T5C8; Q9NSE3"	"Cytosolic tRNA aminoacylation; Selenocysteine synthesis"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"558.4"	"396.3"	"485.3"	"480.8"	"411.5"	"383.5"	"785.3"	"11.6"	"6256.8"	"6168.3"	"12322.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24928"	"DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2"	"0.000"	""	"11"	"17"	"29"	"17"	"1970"	"217.0"	"7.37"	"5066.01"	"51.68"	"13"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04990, Pf04992, Pf04997, Pf04998, Pf05000, Pf05001"	"5430"	""	"POLR2A"	"A6NN93; B9EH88; hsa:5430; P24928; Q6NX41"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; mRNA processing"	"44"	"0"	"754.4"	"622.0"	"734.1"	"699.3"	"720.6"	"637.4"	"1194.6"	"8.4"	"4822.8"	"4919.1"	"9157.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT25"	"Serine/threonine-protein kinase MRCK alpha OS=Homo sapiens OX=9606 GN=CDC42BPA PE=1 SV=1"	"0.000"	""	"12"	"17"	"31"	"14"	"1732"	"197.2"	"6.58"	"5653.49"	"51.65"	"14"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433, Pf00780, Pf08826, Pf15796"	"8476"	"ENSG00000143776"	"CDC42BPA"	"hsa:8476; O75039; Q59GZ1; Q5H9N9; Q5T797; Q5VT25; Q5VT26; Q5VT27; Q86XX2; Q86XX3; Q99646"	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"Male infertility"	"5"	"1"	"172.1"	"99.7"	"186.2"	"184.5"	"222.7"	"212.2"	"532.3"	"46.5"	"4696.1"	"4602.6"	"7078.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AC1"	"Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1"	"0.000"	""	"20"	"10"	"24"	"10"	"680"	"77.8"	"6.70"	"4435.45"	"51.57"	"7"	"9"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf18124"	"10979"	"ENSG00000073712"	"FERMT2"	"B5TJY2; hsa:10979; Q14840; Q86TY7; Q96AC1"	"RAC1 GTPase cycle; RAC3 GTPase cycle; Cell-extracellular matrix interactions"	""	"3"	"0"	"96.7"	"58.5"	"94.4"	"73.2"	"109.2"	"106.0"	"289.6"	"24.6"	"2787.2"	"3311.2"	"5380.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49959"	"Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3"	"0.000"	""	"17"	"10"	"24"	"10"	"708"	"80.5"	"5.90"	"5561.49"	"51.47"	"10"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00149, Pf04152"	"4361"	"ENSG00000020922"	"MRE11"	"B3KTC7; hsa:4361; O43475; P49959"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Cytosolic sensors of pathogen-associated DNA ; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks; IRF3-mediated induction of type I IFN"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"32"	"0"	"287.9"	"203.2"	"287.7"	"279.0"	"297.3"	"259.8"	"452.2"	"15.8"	"2907.4"	"2898.3"	"6801.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92804"	"TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1"	"0.000"	""	"24"	"10"	"21"	"6"	"592"	"61.8"	"8.02"	"1606.59"	"51.45"	"4"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"8148"	"ENSG00000270647; ENSG00000276833"	"TAF15"	"B2R837; hsa:8148; Q86X94; Q92751; Q92804"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"17q12 copy number variation syndrome"	"10"	"0"	"155.0"	"97.9"	"123.7"	"133.9"	"104.3"	"98.1"	"277.3"	"1.4"	"786.1"	"727.5"	"1295.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35659"	"Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1"	"0.000"	""	"17"	"8"	"22"	"8"	"375"	"42.6"	"8.56"	"3039.95"	"51.44"	"5"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08766"	"7913"	"ENSG00000124795"	"DEK"	"B2R6K6; B4DN37; hsa:7913; P35659; Q5TGV4; Q5TGV5"	"B-WICH complex positively regulates rRNA expression; Transcriptional regulation of granulopoiesis; Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	"IL-18 signaling pathway; 10q11.21q11.23 copy number variation syndrome"	"5"	"0"	"116.8"	"85.3"	"126.7"	"101.4"	"124.9"	"133.9"	"237.4"	"14.2"	"5062.9"	"5365.7"	"13047.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30419"	"Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2"	"0.000"	""	"29"	"11"	"22"	"10"	"496"	"56.8"	"7.80"	"4282.41"	"51.19"	"8"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"4836"	"ENSG00000136448"	"NMT1"	"A8K7C1; hsa:4836; P30419; Q9UE09"	"Inactivation, recovery and regulation of the phototransduction cascade; Late Phase of HIV Life Cycle; Activation, myristolyation of BID and translocation to mitochondria"	""	"3"	"1"	"244.9"	"173.3"	"247.5"	"217.1"	"245.7"	"223.8"	"409.1"	"29.8"	"5045.7"	"5045.5"	"10901.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3U4"	"Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3"	"0.000"	""	"13"	"13"	"21"	"13"	"1231"	"141.2"	"5.43"	"2261.52"	"51.04"	"6"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10735"	"ENSG00000101972"	"STAG2"	"B1AMT5; D3DTF5; hsa:10735; O00540; Q5JTI6; Q68DE9; Q8N3U4; Q9H1N8"	"Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Separation of Sister Chromatids; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cell cycle; Cohesin complex - Cornelia de Lange syndrome"	"9"	"0"	"115.4"	"88.5"	"147.2"	"115.5"	"142.4"	"128.7"	"219.3"	"9.4"	"2360.9"	"2385.5"	"6108.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCS8"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2"	"0.000"	""	"19"	"11"	"26"	"11"	"783"	"85.9"	"7.77"	"5038.19"	"50.72"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf01138, Pf03725, Pf03726"	"87178"	"ENSG00000138035"	"PNPT1"	"hsa:87178; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q8TCS8; Q96T05; Q9BRU3; Q9BVX0"	""	"Pyrimidine metabolism; miRNA degrading enzymes"	"2"	"0"	"240.7"	"229.8"	"246.7"	"225.0"	"206.0"	"231.3"	"469.6"	"3.6"	"2867.5"	"2744.8"	"4400.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05023"	"Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1"	"0.000"	""	"12"	"11"	"24"	"11"	"1023"	"112.8"	"5.49"	"4103.39"	"50.68"	"9"	"11"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf13246"	"476"	"ENSG00000163399"	"ATP1A1"	"B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; hsa:476; P05023; Q16689; Q6LDM4; Q9UCN1; Q9UJ20; Q9UJ21"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases"	"Pre-implantation embryo; Proximal tubule transport; Arsenic metabolism and reactive oxygen species generation"	"6"	"0"	"222.8"	"135.5"	"241.8"	"208.6"	"211.1"	"186.1"	"405.8"	"16.8"	"4336.5"	"4337.7"	"8961.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15365"	"Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2"	"0.000"	""	"39"	"11"	"20"	"5"	"356"	"37.5"	"7.09"	"2985.38"	"50.61"	"7"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5093"	"ENSG00000169564"	"PCBP1"	"hsa:5093; Q13157; Q14975; Q15365"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"Ferroptosis"	"3"	"6"	"230.2"	"177.9"	"315.2"	"232.8"	"242.8"	"224.3"	"586.4"	"10.4"	"3783.6"	"3799.4"	"8330.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56192"	"Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2"	"0.000"	""	"19"	"10"	"16"	"10"	"900"	"101.1"	"6.16"	"1954.98"	"50.59"	"5"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf09334, Pf18485, Pf19303"	"4141"	"ENSG00000166986"	"MARS1"	"B3KVK7; hsa:4141; P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	""	"2"	"0"	"199.8"	"120.2"	"242.0"	"229.6"	"199.1"	"158.3"	"311.9"	"23.1"	"3319.2"	"3352.5"	"7826.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95747"	"Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1"	"0.000"	""	"23"	"9"	"21"	"8"	"527"	"58.0"	"6.43"	"3170.01"	"50.40"	"5"	"8"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"9943"	"ENSG00000172939"	"OXSR1"	"hsa:9943; O95747; Q3LR53; Q7Z501; Q9UPQ1"	""	""	"0"	"2"	"82.0"	"54.9"	"96.9"	"75.9"	"89.9"	"103.5"	"174.8"	"12.4"	"3894.9"	"4030.1"	"8279.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EE3"	"Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3"	"0.000"	""	"30"	"8"	"21"	"8"	"360"	"39.6"	"8.09"	"4397.23"	"50.29"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"81929"	"ENSG00000085415"	"SEH1L"	"A8K5B1; hsa:81929; Q8NFU6; Q96EE3; Q96MH3; Q9C069"	"Amino acids regulate mTORC1"	""	"1"	"0"	"157.4"	"163.5"	"175.3"	"178.8"	"164.8"	"149.6"	"354.5"	"5.9"	"2427.2"	"2446.0"	"4959.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18754"	"Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1"	"0.000"	""	"24"	"10"	"24"	"10"	"421"	"44.9"	"7.52"	"4267.51"	"50.23"	"8"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00415"	"1104"	"ENSG00000180198"	"RCC1"	"hsa:1104; P18754; Q16269; Q6NT97"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation"	"22q11.2 copy number variation syndrome"	"4"	"0"	"457.9"	"395.3"	"493.5"	"418.7"	"466.0"	"442.5"	"793.2"	"4.5"	"4126.7"	"4013.2"	"8026.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1J9"	"Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1"	"0.000"	""	"29"	"13"	"30"	"13"	"531"	"60.5"	"9.61"	"4829.98"	"49.74"	"12"	"13"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05179, Pf16050"	"79577"	"ENSG00000134371"	"CDC73"	"A6NLZ8; B2RBR2; hsa:79577; Q6P1J9; Q6PK51; Q96A07; Q9H245; Q9H5L7"	"Hedgehog 'on' state; RNA Polymerase II Pre-transcription Events; Formation of the beta-catenin:TCF transactivating complex; E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex"	"Endoderm differentiation"	"7"	"0"	"798.3"	"658.9"	"812.0"	"734.9"	"646.2"	"742.8"	"1870.3"	"7.2"	"5111.3"	"5029.2"	"8485.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61604"	"10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2"	"0.000"	""	"78"	"11"	"26"	"11"	"102"	"10.9"	"8.92"	"4217.68"	"49.67"	"8"	"11"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00166"	"3336"	"ENSG00000115541"	"HSPE1"	"hsa:3336; O95421; P61604; Q04984; Q53X54; Q9UDH0"	"RHOG GTPase cycle"	""	"1"	"0"	"493.4"	"344.8"	"460.1"	"379.1"	"493.1"	"1151.9"	"2831.4"	"29.1"	"14617.6"	"13704.1"	"24266.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48643"	"T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1"	"0.000"	""	"27"	"14"	"24"	"14"	"541"	"59.6"	"5.66"	"4637.26"	"49.40"	"9"	"12"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00118"	"22948"	"ENSG00000150753"	"CCT5"	"A8JZY8; A8K2X8; B4DYD8; hsa:22948; P48643"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"324.2"	"227.6"	"404.3"	"346.0"	"333.7"	"299.5"	"589.3"	"19.3"	"6371.3"	"6631.2"	"18119.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62081"	"40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1"	"0.000"	""	"53"	"8"	"15"	"8"	"194"	"22.1"	"10.10"	"1813.88"	"49.24"	"4"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01251"	"6201"	"ENSG00000171863"	"RPS7"	"hsa:6201; P23821; P24818; P62081; Q57Z92; Q6IPH1"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; rRNA modification in the nucleus and cytosol"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"93.1"	"84.4"	"114.5"	"91.2"	"115.0"	"109.2"	"233.3"	"10.2"	"3916.6"	"4025.1"	"9540.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00341"	"Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2"	"0.000"	""	"12"	"12"	"20"	"12"	"1268"	"141.4"	"6.87"	"3258.07"	"49.07"	"7"	"12"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"3069"	"ENSG00000115677"	"HDLBP"	"B4DTQ2; E7EM71; hsa:3069; Q00341; Q53QU2; Q9UCY3"	"HDL clearance"	"2q37 copy number variation syndrome"	"2"	"0"	"162.1"	"111.8"	"179.1"	"167.0"	"179.6"	"159.0"	"316.7"	"9.7"	"2169.7"	"2193.8"	"4374.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42166"	"Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"0.000"	""	"18"	"11"	"17"	"5"	"694"	"75.4"	"7.66"	"3312.98"	"48.51"	"7"	"10"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198, Pf11560"	"7112"	"ENSG00000120802"	"TMPO"	"P08918; P08919; P42166; Q14860; Q16295"	""	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"2"	"6"	"238.3"	"182.7"	"228.2"	"239.6"	"206.8"	"235.3"	"386.9"	"2.5"	"3157.6"	"3183.1"	"6146.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00567"	"Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4"	"0.000"	""	"16"	"8"	"18"	"8"	"594"	"66.0"	"9.19"	"3933.84"	"48.46"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"10528"	"ENSG00000101361"	"NOP56"	"hsa:10528; O00567; Q2M3T6; Q9NQ05"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	""	"3"	"0"	"180.6"	"141.3"	"164.5"	"171.5"	"138.6"	"156.2"	"282.6"	"2.6"	"2314.8"	"2196.8"	"4349.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12972"	"Nuclear inhibitor of protein phosphatase 1 OS=Homo sapiens OX=9606 GN=PPP1R8 PE=1 SV=2"	"0.000"	""	"33"	"8"	"17"	"8"	"351"	"38.5"	"7.37"	"3882.76"	"47.30"	"6"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00498"	"5511"	"ENSG00000117751"	"PPP1R8"	"hsa:5511; Q12972; Q5TEJ2; Q5TEJ4; Q5TIF2; Q6PKF6; Q9UBH1; Q9UBZ0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"197.8"	"171.9"	"230.1"	"219.2"	"211.6"	"234.1"	"291.1"	"4.7"	"3494.1"	"3654.4"	"6537.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51659"	"Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3"	"0.000"	""	"19"	"12"	"23"	"12"	"736"	"79.6"	"8.84"	"4007.75"	"47.17"	"9"	"12"	"other metabolic processes;developmental processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf01575, Pf02036"	"3295"	"ENSG00000133835"	"HSD17B4"	"B4DNV1; B4DVS5; E9PB82; F5HE57; hsa:3295; P51659"	"TYSND1 cleaves peroxisomal proteins; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"Androgen receptor network in prostate cancer; Steroid biosynthesis; Disorders of bile acid synthesis and biliary transport; Primary ovarian insufficiency"	"10"	"0"	"346.5"	"239.6"	"288.5"	"262.0"	"293.3"	"265.9"	"427.7"	"18.0"	"4196.4"	"4262.3"	"8689.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82970"	"High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1"	"0.000"	""	"35"	"8"	"17"	"8"	"282"	"31.5"	"4.55"	"2684.85"	"47.14"	"4"	"8"	"cell organization and biogenesis;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"79366"	"ENSG00000198157"	"HMGN5"	"hsa:79366; P82970; Q5JSL1"	""	""	"0"	"0"	"83.5"	"66.8"	"104.5"	"109.8"	"85.5"	"110.3"	"176.7"	"4.7"	"5170.2"	"5144.9"	"10967.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62633"	"Cellular nucleic acid-binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1"	"0.000"	""	"41"	"7"	"12"	"7"	"177"	"19.5"	"7.71"	"413.38"	"46.95"	"1"	"7"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098"	"7555"	"ENSG00000169714"	"CNBP"	"A8K7V4; B2RAV9; B4DP17; D3DNB9; D3DNC0; D3DNC1; E9PDR7; hsa:7555; P20694; P62633; Q4JGY0; Q4JGY1; Q5QJR0; Q5U0E9; Q6PJI7; Q96NV3"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"1"	"0"	"177.5"	"211.4"	"160.4"	"181.5"	"125.8"	"73.8"	"435.8"	"9.5"	"2550.8"	"2902.6"	"3862.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3R9"	"MAGUK p55 subfamily member 5 OS=Homo sapiens OX=9606 GN=MPP5 PE=1 SV=3"	"0.000"	""	"24"	"12"	"18"	"12"	"675"	"77.2"	"6.14"	"3551.02"	"46.41"	"5"	"10"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf02828, Pf07653, Pf09060"	"64398"	"ENSG00000072415"	"PALS1"	"A1L380; hsa:64398; Q7Z631; Q86T98; Q8N3R9; Q8N7I5; Q9H9Q0"	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction; SARS-CoV-1 targets PDZ proteins in cell-cell junction"	"Epithelial to mesenchymal transition in colorectal cancer; Complement system in neuronal development and plasticity"	"5"	"0"	"290.1"	"200.0"	"303.5"	"264.3"	"257.4"	"275.7"	"504.6"	"10.7"	"4450.8"	"4248.6"	"9288.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61158"	"Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3"	"0.000"	""	"34"	"11"	"22"	"11"	"418"	"47.3"	"5.88"	"3839.83"	"46.31"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10096"	"ENSG00000115091"	"ACTR3"	"hsa:10096; P32391; P61158; Q53QM2"	"EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis"	"Physico-chemical features and toxicity-associated pathways"	"6"	"0"	"309.9"	"266.8"	"312.8"	"324.6"	"335.7"	"361.1"	"930.3"	"3.8"	"5983.5"	"6047.9"	"11748.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08708"	"40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2"	"0.000"	""	"56"	"6"	"12"	"6"	"135"	"15.5"	"9.85"	"1170.56"	"46.29"	"3"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00833"	"6218"	"ENSG00000182774; ENSG00000278229"	"RPS17"	"B2R4U4; hsa:6218; P08708; P0CW22"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"187.8"	"130.7"	"159.4"	"149.1"	"167.4"	"159.3"	"517.3"	"9.5"	"2357.9"	"2460.3"	"3796.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35527"	"Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3"	"0.000"	""	"27"	"12"	"22"	"11"	"623"	"62.0"	"5.24"	"3576.12"	"46.18"	"9"	"10"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3857"	"ENSG00000171403"	"KRT9"	"hsa:3857; O00109; P35527; Q0IJ47; Q14665"	"Formation of the cornified envelope"	""	"2"	"1"	"657.2"	"563.0"	"786.6"	"981.3"	"776.9"	"5845.6"	"1958.3"	"0.0"	"2052.5"	"2399.3"	"5840.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47813"	"Eukaryotic translation initiation factor 1A, X-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AX PE=1 SV=2"	"0.000"	""	"69"	"9"	"21"	"9"	"144"	"16.5"	"5.24"	"4385.43"	"46.17"	"8"	"7"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"1964"	"ENSG00000173674"	"EIF1AX"	"B2R5U5; hsa:1964; P47813; Q0VGC2; Q5JPS5; Q5JPS6"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"57.2"	"42.0"	"90.6"	"72.1"	"89.7"	"71.1"	"172.3"	"10.8"	"7471.2"	"8149.3"	"13900.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NVY1"	"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBCH PE=1 SV=2"	"0.000"	""	"40"	"13"	"29"	"13"	"386"	"43.5"	"8.19"	"6081.01"	"45.94"	"11"	"12"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf16113"	"26275"	"ENSG00000198130"	"HIBCH"	"D3DPI4; hsa:26275; Q53GA8; Q53GF2; Q53RF7; Q53TC6; Q6NVY1; Q92931; Q9BS94"	"Branched-chain amino acid catabolism"	"Amino acid metabolism"	"2"	"0"	"86.8"	"55.9"	"133.4"	"93.4"	"106.9"	"110.3"	"207.3"	"27.1"	"7052.0"	"7104.6"	"12203.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31946"	"14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3"	"0.000"	""	"48"	"10"	"25"	"5"	"246"	"28.1"	"4.83"	"5614.62"	"45.85"	"10"	"8"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00244"	"7529"	"ENSG00000166913"	"YWHAB"	"A8K9K2; E1P616; hsa:7529; P31946"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Rap1 signalling; Negative regulation of MAPK pathway; Frs2-mediated activation; ARMS-mediated activation; Activation of BAD and translocation to mitochondria ; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"Cell cycle; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Hepatitis B infection; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"33"	"1"	"498.4"	"386.5"	"438.2"	"466.0"	"394.0"	"354.5"	"645.5"	"2.7"	"1988.0"	"2040.4"	"3218.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43852"	"Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2"	"0.000"	""	"40"	"11"	"23"	"11"	"315"	"37.1"	"4.64"	"4462.48"	"45.80"	"10"	"11"	""	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf13833"	"813"	"ENSG00000128595"	"CALU"	"B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879; hsa:813; O43852; O60456; Q6FHB9; Q96RL3; Q9NR43"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"NOTCH1 regulation of endothelial cell calcification; VEGFA-VEGFR2 signaling"	"5"	"0"	"1056.9"	"653.8"	"848.5"	"915.6"	"1095.2"	"873.4"	"1247.3"	"3.7"	"2692.1"	"2478.3"	"4066.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y314"	"Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1"	"0.000"	""	"44"	"10"	"18"	"10"	"301"	"33.2"	"8.82"	"3449.24"	"45.39"	"7"	"9"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf15906"	"51070"	"ENSG00000142546"	"NOSIP"	"hsa:51070; Q96FD2; Q9Y314"	"NOSIP mediated eNOS trafficking"	""	"1"	"0"	"242.8"	"202.8"	"252.0"	"235.8"	"211.8"	"245.9"	"421.4"	"18.2"	"3935.7"	"3900.7"	"7665.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUA2"	"Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1"	"0.000"	""	"21"	"10"	"20"	"10"	"492"	"57.2"	"5.92"	"2861.98"	"45.25"	"7"	"10"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00160"	"85313"	"ENSG00000131013"	"PPIL4"	"B2RD34; hsa:85313; Q7Z3Q5; Q8WUA2"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"175.4"	"129.8"	"193.5"	"173.7"	"167.7"	"188.2"	"355.6"	"5.1"	"4545.2"	"4537.1"	"9530.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95831"	"Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1"	"0.000"	""	"22"	"11"	"20"	"11"	"613"	"66.9"	"8.95"	"4149.34"	"45.25"	"10"	"9"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00070, Pf14721"	"9131"	"ENSG00000156709"	"AIFM1"	"A4QPB4; B1ALN1; B2RB08; D3DTE9; E9PRR0; hsa:9131; O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4"	""	"Apoptosis modulation and signaling; Nanomaterial induced apoptosis; Apoptosis modulation by HSP70"	"3"	"0"	"325.9"	"277.0"	"350.5"	"298.8"	"320.0"	"332.6"	"545.7"	"17.6"	"4291.1"	"4492.2"	"10148.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5UIP0"	"Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2"	"0.000"	""	"5"	"10"	"19"	"10"	"2472"	"274.3"	"5.52"	"3661.35"	"45.22"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	""	"Pf12231"	"55183"	"ENSG00000080345"	"RIF1"	"A6NC27; C9JBR1; hsa:55183; Q5H9R3; Q5UIP0; Q5UIP2; Q66YK6; Q6PRU2; Q8TE94; Q99772; Q9H830; Q9H9B9; Q9NVP5; Q9Y4R4"	"Nonhomologous End-Joining (NHEJ)"	"ATM signaling in development and disease ; 10q11.21q11.23 copy number variation syndrome"	"3"	"0"	"193.3"	"139.4"	"180.1"	"178.0"	"176.4"	"183.4"	"368.2"	"3.8"	"2296.9"	"2149.9"	"4458.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94906"	"Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1"	"0.000"	""	"17"	"17"	"30"	"17"	"941"	"106.9"	"8.25"	"4365.93"	"45.21"	"14"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06424, Pf13181"	"24148"	"ENSG00000101161"	"PRPF6"	"B2RAR5; B3KMC6; hsa:24148; O94906; O95109; Q5VXS5; Q9H3Z1; Q9H4T9; Q9H4U8; Q9NTE6"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"463.1"	"360.7"	"474.8"	"447.4"	"421.2"	"416.8"	"968.8"	"13.1"	"4958.8"	"5418.1"	"12637.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15366"	"Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1"	"0.000"	""	"29"	"10"	"22"	"3"	"365"	"38.6"	"6.79"	"3707.21"	"45.16"	"8"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5094"	"ENSG00000197111"	"PCBP2"	"A8K7X6; B4DXP5; F8VYL7; G3V0E8; hsa:5094; I6L8F9; Q15366; Q32Q82; Q59HD4; Q68Y55; Q6IPF4; Q6PKG5"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses"	"mRNA processing; Ferroptosis; Modulators of TCR signaling and T cell activation"	"7"	"1"	"135.2"	"114.5"	"145.2"	"127.5"	"118.5"	"124.2"	"369.7"	"1.5"	"2506.2"	"2522.4"	"5012.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43795"	"Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3"	"0.000"	""	"11"	"11"	"24"	"10"	"1136"	"131.9"	"9.38"	"4004.30"	"45.13"	"9"	"11"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4430"	"ENSG00000128641"	"MYO1B"	"hsa:4430; O43794; O43795; Q7Z6L5"	""	""	"0"	"0"	"158.8"	"142.9"	"193.4"	"162.8"	"175.6"	"197.0"	"455.1"	"7.6"	"3741.0"	"3881.9"	"7314.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNF0"	"Protein kinase C and casein kinase substrate in neurons protein 2 OS=Homo sapiens OX=9606 GN=PACSIN2 PE=1 SV=2"	"0.000"	""	"24"	"11"	"21"	"11"	"486"	"55.7"	"5.20"	"3411.53"	"45.13"	"8"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00611"	"11252"	"ENSG00000100266"	"PACSIN2"	"hsa:11252; O95921; Q96HV9; Q9H0D3; Q9NPN1; Q9UNF0; Q9Y4V2"	"Clathrin-mediated endocytosis"	""	"1"	"0"	"66.8"	"53.7"	"78.8"	"67.3"	"74.2"	"80.9"	"144.2"	"8.7"	"3394.3"	"3629.6"	"8544.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43583"	"Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2"	"0.000"	""	"34"	"5"	"16"	"5"	"198"	"22.1"	"5.30"	"1709.45"	"45.00"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"nucleic acid binding activity"	"Pf01253"	"8562"	"ENSG00000139726"	"DENR"	"hsa:8562; O43583; Q9H3U6; Q9UKZ0"	""	""	"0"	"0"	"34.8"	"34.3"	"48.3"	"45.2"	"57.1"	"89.4"	"156.9"	"14.4"	"2775.0"	"2886.2"	"4839.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57740"	"Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1"	"0.000"	""	"9"	"7"	"18"	"7"	"925"	"106.3"	"5.43"	"3943.18"	"44.99"	"6"	"7"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04121"	"57122"	"ENSG00000111581"	"NUP107"	"B4DZ67; hsa:57122; P57740; Q6PJE1"	"snRNP Assembly; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; SUMOylation of RNA binding proteins; Regulation of HSF1-mediated heat shock response; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"Gastric cancer network 1; Primary ovarian insufficiency"	"37"	"0"	"409.4"	"303.8"	"381.8"	"415.6"	"379.1"	"263.5"	"418.7"	"5.0"	"2330.6"	"2325.1"	"5016.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15371"	"Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1"	"0.000"	""	"28"	"10"	"15"	"10"	"548"	"63.9"	"6.05"	"1663.22"	"44.75"	"4"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf05091"	"8664"	"ENSG00000100353"	"EIF3D"	"A8MWD3; B2R7D4; B4DTF8; B4DVY1; hsa:8664; O15371; Q3MJD9; Q5M9Q6"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"9"	"0"	"253.8"	"162.5"	"314.9"	"252.7"	"270.1"	"237.3"	"409.9"	"3.3"	"1658.8"	"1560.0"	"4439.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13428"	"Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3"	"0.000"	""	"11"	"17"	"30"	"17"	"1488"	"152.0"	"9.04"	"6067.70"	"44.64"	"16"	"14"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03546"	"6949"	"ENSG00000070814"	"TCOF1"	"A0JLU0; B4E111; hsa:6949; Q13428; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860"	""	""	"0"	"0"	"1383.3"	"1053.7"	"1129.1"	"1180.1"	"994.3"	"1149.8"	"1781.1"	"6.9"	"5547.4"	"5659.1"	"10233.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23588"	"Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2"	"0.000"	""	"18"	"10"	"23"	"10"	"611"	"69.1"	"5.73"	"3428.03"	"44.53"	"8"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf00076"	"1975"	"ENSG00000063046"	"EIF4B"	"B4DS13; hsa:1975; P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; mTORC1-mediated signalling"	"Translation factors; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Pleural mesothelioma; Interferon type I signaling pathways"	"14"	"0"	"199.2"	"154.6"	"238.2"	"205.0"	"198.9"	"187.1"	"317.2"	"9.8"	"4284.8"	"4365.7"	"8380.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32119"	"Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5"	"0.000"	""	"54"	"10"	"20"	"9"	"198"	"21.9"	"5.97"	"4316.84"	"44.49"	"8"	"8"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"7001"	"ENSG00000167815"	"PRDX2"	"A8K0C0; hsa:7001; P31945; P32118; P32119; P35701; Q6FHG4; Q92763; Q9UC23"	"TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Selenium micronutrient network; VEGFA-VEGFR2 signaling"	"5"	"0"	"106.6"	"72.4"	"145.2"	"98.5"	"118.2"	"100.5"	"198.7"	"3.8"	"4470.7"	"4663.5"	"9354.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68431"	"Histone H3.1 OS=Homo sapiens OX=9606 GN=H3C1 PE=1 SV=2"	"0.000"	""	"63"	"9"	"22"	"1"	"136"	"15.4"	"11.12"	"3441.10"	"44.32"	"8"	"7"	"cell organization and biogenesis;other metabolic processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968"	"ENSG00000197153; ENSG00000197409; ENSG00000273983; ENSG00000274750; ENSG00000275379; ENSG00000275714; ENSG00000277775; ENSG00000278828; ENSG00000286522; ENSG00000287080"	"H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8"	"A0PJT7; A5PLR1; hsa:8350; hsa:8351; hsa:8352; hsa:8353; hsa:8354; hsa:8355; hsa:8356; hsa:8357; hsa:8358; hsa:8968; P02295; P02296; P16106; P68431; Q6ISV8; Q6NWP8; Q6NWP9; Q6NXU4; Q71DJ3; Q93081"	"Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; HATs acetylate histones; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; Transcriptional regulation of granulopoiesis; Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Interleukin-7 signaling; RMTs methylate histone arginines; PKMTs methylate histone lysines"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"36"	"10"	"684.4"	"507.9"	"744.8"	"529.1"	"436.8"	"742.0"	"1668.7"	"16.6"	"5661.6"	"5332.7"	"11216.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12268"	"Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2"	"0.000"	""	"25"	"9"	"19"	"9"	"514"	"55.8"	"6.90"	"4797.08"	"43.97"	"9"	"8"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00478, Pf00571"	"3615"	"ENSG00000178035"	"IMPDH2"	"hsa:3615; P12268; Q6LEF3"	"Potential therapeutics for SARS; Neutrophil degranulation; Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"Rett syndrome causing genes"	"5"	"0"	"154.0"	"113.0"	"145.6"	"130.7"	"131.6"	"128.7"	"261.1"	"5.3"	"3362.2"	"3480.8"	"7672.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40227"	"T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3"	"0.000"	""	"25"	"11"	"24"	"11"	"531"	"58.0"	"6.68"	"5112.35"	"43.84"	"8"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"908"	"ENSG00000146731"	"CCT6A"	"A6NCD2; hsa:908; P40227; Q3KP28; Q75LP4; Q96S46"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"16p11.2 proximal deletion syndrome"	"7"	"0"	"188.6"	"127.7"	"212.0"	"165.1"	"194.4"	"179.7"	"343.1"	"23.4"	"4137.2"	"4531.8"	"11153.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07900"	"Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5"	"0.000"	""	"17"	"9"	"16"	"3"	"732"	"84.6"	"5.02"	"2038.79"	"43.70"	"5"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3320"	"ENSG00000080824"	"HSP90AA1"	"A8K500; B3KPJ9; hsa:3320; P07900; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5"	"Estrogen-dependent gene expression; Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Extra-nuclear estrogen signaling; Neutrophil degranulation; vRNP Assembly; Regulation of necroptotic cell death; Interleukin-4 and Interleukin-13 signaling; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; PIWI-interacting RNA (piRNA) biogenesis; VEGFR2 mediated vascular permeability; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Uptake and function of diphtheria toxin; Constitutive Signaling by Overexpressed ERBB2; Scavenging by Class F Receptors; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"Nucleotide-binding oligomerization domain (NOD) pathway; TNF-alpha signaling pathway; Corticotropin-releasing hormone signaling pathway; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Aryl hydrocarbon receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Th17 cell differentiation pathway"	"67"	"0"	"29.9"	"19.5"	"37.7"	"28.7"	"31.5"	"36.1"	"51.7"	"2.0"	"407.9"	"403.8"	"830.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30040"	"Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4"	"0.000"	""	"47"	"10"	"16"	"10"	"261"	"29.0"	"7.31"	"1591.46"	"43.31"	"4"	"10"	"protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf07749, Pf07912"	"10961"	"ENSG00000089248"	"ERP29"	"C9J183; hsa:10961; P30040; Q3MJC3; Q6FHT4"	""	""	"0"	"0"	"68.2"	"45.7"	"88.6"	"81.5"	"72.8"	"71.8"	"124.4"	"3.8"	"3331.8"	"3685.8"	"6375.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N7H5"	"RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2"	"0.000"	""	"26"	"13"	"23"	"13"	"531"	"59.9"	"4.63"	"3984.25"	"43.26"	"11"	"12"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03985"	"54623"	"ENSG00000006712"	"PAF1"	"hsa:54623; M0QX35; O75239; Q8N7H5; Q9H166; Q9NUU9"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"Endoderm differentiation"	"5"	"0"	"1301.3"	"1090.4"	"1159.8"	"1134.8"	"1055.3"	"1086.0"	"2008.0"	"4.0"	"5054.9"	"5001.0"	"9011.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"E9PAV3"	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1"	"0.000"	""	"4"	"6"	"18"	"6"	"2078"	"205.3"	"9.58"	"2805.46"	"43.22"	"5"	"6"	"transport"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01849, Pf19026"	""	"ENSG00000196531"	"NACA"	"E9PAV3"	""	""	"0"	"0"	"70.1"	"40.6"	"85.0"	"65.9"	"87.3"	"74.0"	"172.1"	"12.8"	"1823.1"	"2070.5"	"5762.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62753"	"40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1"	"0.000"	""	"31"	"10"	"26"	"10"	"249"	"28.7"	"10.84"	"5225.55"	"43.10"	"10"	"9"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01092"	"6194"	"ENSG00000137154"	"RPS6"	"hsa:6194; P08227; P10660; P62753; Q4VBY7; Q8N6Z7"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; mTORC1-mediated signalling; rRNA modification in the nucleus and cytosol; Nuclear events stimulated by ALK signaling in cancer"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Cytoplasmic ribosomal proteins; EGFR tyrosine kinase inhibitor resistance; IL-2 signaling pathway; Pleural mesothelioma; 2q37 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"47"	"0"	"1054.5"	"892.2"	"970.3"	"900.6"	"877.6"	"898.2"	"2778.4"	"6.4"	"6377.5"	"6237.7"	"10489.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15924"	"Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3"	"0.000"	""	"5"	"13"	"22"	"13"	"2871"	"331.6"	"6.81"	"2968.18"	"43.02"	"9"	"13"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00681, Pf17902, Pf18373"	"1832"	"ENSG00000096696"	"DSP"	"B2RTT2; D7RX09; hsa:1832; O75993; P15924; Q14189; Q9UHN4"	"Formation of the cornified envelope; Neutrophil degranulation; RND3 GTPase cycle; RND1 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"Arrhythmogenic right ventricular cardiomyopathy; Lung fibrosis; Epithelial to mesenchymal transition in colorectal cancer"	"9"	"0"	"549.9"	"449.4"	"560.8"	"545.9"	"459.5"	"647.9"	"1021.2"	"8.4"	"4028.3"	"4061.6"	"7499.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1G4"	"Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1"	"0.000"	""	"23"	"11"	"19"	"11"	"583"	"63.4"	"8.28"	"3281.36"	"42.97"	"8"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00560, Pf03483, Pf12799"	"57470"	"ENSG00000130764"	"LRRC47"	"hsa:57470; Q8N1G4; Q9ULN5"	""	""	"0"	"0"	"147.4"	"118.5"	"164.5"	"139.2"	"164.5"	"130.0"	"269.4"	"14.0"	"3856.5"	"3982.0"	"8048.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVP1"	"ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2"	"0.000"	""	"14"	"6"	"11"	"6"	"670"	"75.4"	"9.50"	"1989.40"	"42.82"	"3"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"8886"	"ENSG00000088205"	"DDX18"	"hsa:8886; Q6GTZ9; Q6IAU4; Q92732; Q9BQB7; Q9NVP1"	""	""	"0"	"0"	"148.2"	"129.6"	"137.1"	"140.8"	"150.3"	"162.2"	"528.9"	"10.1"	"2586.7"	"2560.9"	"4727.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23381"	"Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2"	"0.000"	""	"29"	"10"	"15"	"10"	"471"	"53.1"	"6.23"	"1719.62"	"42.79"	"5"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00458, Pf00579"	"7453"	"ENSG00000140105"	"WARS1"	"A6NGN1; A6NID3; hsa:7453; P23381; P78535; Q502Y0; Q53XB6; Q9UDI5; Q9UDL3"	"Cytosolic tRNA aminoacylation"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"3"	"0"	"49.5"	"31.8"	"56.5"	"46.6"	"58.6"	"52.1"	"90.4"	"26.2"	"2944.7"	"3010.4"	"6673.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6T3"	"RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2"	"0.000"	""	"25"	"13"	"24"	"13"	"665"	"75.7"	"6.84"	"5092.97"	"42.76"	"10"	"10"	"other biological processes"	"cytosol;other cell component"	""	"Pf00515, Pf13176, Pf13181, Pf13877"	"79657"	"ENSG00000005175"	"RPAP3"	"B4DRW9; hsa:79657; Q6PHR5; Q9H6T3"	""	""	"0"	"0"	"207.2"	"134.2"	"198.9"	"188.8"	"172.8"	"196.5"	"355.8"	"12.0"	"4600.7"	"4562.9"	"9724.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60716"	"Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1"	"0.000"	""	"15"	"12"	"24"	"12"	"968"	"108.1"	"6.23"	"4805.27"	"42.76"	"10"	"10"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00514"	"1500"	"ENSG00000198561"	"CTNND1"	"A8K939; hsa:1500; O15088; O60713; O60714; O60715; O60716; O60935; Q6DHZ7; Q6RBX8; Q9UP71; Q9UP72; Q9UP73"	"VEGFR2 mediated vascular permeability; Adherens junctions interactions; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency"	"8"	"0"	"609.6"	"501.0"	"544.4"	"547.8"	"568.9"	"585.1"	"882.6"	"16.1"	"5406.0"	"5538.4"	"10941.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NHR9"	"Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2"	"0.000"	""	"7"	"12"	"24"	"12"	"2005"	"226.2"	"7.30"	"4512.37"	"42.62"	"12"	"12"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06470, Pf13589"	"23347"	"ENSG00000101596"	"SMCHD1"	"A6NHR9; hsa:23347; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39"	""	""	"0"	"0"	"174.8"	"159.1"	"209.3"	"200.4"	"183.0"	"184.4"	"567.2"	"8.8"	"2801.0"	"2787.9"	"5770.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39019"	"40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2"	"0.000"	""	"45"	"9"	"22"	"9"	"145"	"16.1"	"10.32"	"4699.62"	"42.55"	"9"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01090"	"6223"	"ENSG00000105372"	"RPS19"	"hsa:6223; P39019"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Complement system; Cytoplasmic ribosomal proteins"	"20"	"0"	"498.1"	"400.4"	"488.5"	"482.2"	"446.6"	"490.2"	"1890.8"	"3.1"	"5203.0"	"5508.0"	"12521.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ST2"	"Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2"	"0.000"	""	"13"	"9"	"19"	"9"	"819"	"91.9"	"4.69"	"3692.26"	"42.43"	"7"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	""	"Pf08711"	"55677"	"ENSG00000163166"	"IWS1"	"hsa:55677; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q96ST2; Q9NV97; Q9NWH8"	"RNA Polymerase II Pre-transcription Events; Formation of RNA Pol II elongation complex"	""	"3"	"0"	"780.8"	"656.6"	"758.1"	"738.0"	"747.9"	"661.5"	"966.9"	"0.5"	"3161.2"	"3154.0"	"6067.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40222"	"Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3"	"0.000"	""	"27"	"10"	"14"	"10"	"546"	"61.9"	"6.52"	"1488.46"	"42.30"	"3"	"10"	"transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf09728"	"200081"	"ENSG00000084652"	"TXLNA"	"D3DPP6; hsa:200081; P40222; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86; Q86YW3; Q8N2Y3"	"Other interleukin signaling"	""	"1"	"0"	"213.0"	"184.7"	"232.8"	"202.1"	"199.0"	"201.6"	"404.4"	"15.0"	"3785.4"	"3786.9"	"7767.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06576"	"ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3"	"0.000"	""	"16"	"7"	"21"	"7"	"529"	"56.5"	"5.40"	"4791.24"	"42.24"	"7"	"6"	"other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf02874"	"506"	"ENSG00000110955"	"ATP5F1B"	"A8K4X0; hsa:506; P06576; Q14283"	"Transcriptional activation of mitochondrial biogenesis; Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"7"	"0"	"158.2"	"126.1"	"192.7"	"158.9"	"176.5"	"169.4"	"324.2"	"8.1"	"3017.6"	"3012.1"	"6807.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68400"	"Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1"	"0.000"	""	"33"	"9"	"19"	"9"	"391"	"45.1"	"7.74"	"3809.75"	"42.21"	"8"	"9"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1457"	"ENSG00000101266"	"CSNK2A1"	"B4DYS6; D3DVV8; hsa:1457; P19138; P20426; P68400; Q14013; Q5U065"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Translation inhibitors in chronically activated PDGFRA cells; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"21"	"0"	"88.6"	"88.1"	"108.6"	"99.9"	"100.6"	"95.0"	"581.2"	"7.5"	"2236.4"	"2535.7"	"4768.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33991"	"DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5"	"0.000"	""	"16"	"11"	"20"	"11"	"863"	"96.5"	"6.74"	"3574.88"	"42.06"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4173"	"ENSG00000104738"	"MCM4"	"hsa:4173; P33991; Q8NEH1; Q99658"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Gastric cancer network 1; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"12"	"0"	"313.3"	"230.6"	"329.7"	"305.2"	"302.6"	"293.2"	"501.3"	"10.2"	"4025.2"	"4395.5"	"11735.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PK6"	"RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2"	"0.000"	""	"21"	"13"	"28"	"13"	"669"	"69.4"	"9.67"	"5245.81"	"42.04"	"12"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076"	"100526737; 10432"	"ENSG00000239306"	"RBM14"	"B0LM41; B3KMN4; D6RGD8; hsa:100526737; hsa:10432; O75932; Q2PYN1; Q53GV1; Q68DQ9; Q96PK5; Q96PK6"	"RUNX2 regulates bone development"	"Ciliary landscape"	"2"	"0"	"913.0"	"850.4"	"883.4"	"823.7"	"740.7"	"891.6"	"2602.1"	"11.4"	"5537.3"	"5634.7"	"8879.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62736"	"Actin, aortic smooth muscle OS=Homo sapiens OX=9606 GN=ACTA2 PE=1 SV=1"	"0.000"	""	"20"	"9"	"25"	"1"	"377"	"42.0"	"5.39"	"4707.29"	"42.04"	"9"	"8"	"developmental processes;other biological processes"	"extracellular matrix;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"59"	"ENSG00000107796"	"ACTA2"	"B2R8A4; hsa:59; P03996; P04108; P62736; Q6FI19"	"Smooth Muscle Contraction; NOTCH4 Intracellular Domain Regulates Transcription"	"Myometrial relaxation and contraction pathways; Striated muscle contraction pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; 22q11.2 copy number variation syndrome; IL-18 signaling pathway; Regucalcin in proximal tubule epithelial kidney cells; Angiotensin II receptor type 1 pathway; Pleural mesothelioma; CCL18 signaling pathway; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; Comprehensive IL-17A signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling"	"16"	"0"	"22.8"	"31.4"	"41.6"	"34.4"	"27.0"	"30.9"	"81.6"	"1.7"	"791.0"	"802.0"	"1517.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75400"	"Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2"	"0.000"	""	"12"	"11"	"19"	"10"	"957"	"108.7"	"7.56"	"3627.26"	"41.80"	"8"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00397, Pf01846"	"55660"	"ENSG00000196504"	"PRPF40A"	"hsa:55660; O43856; O75400; O75404; Q8TBQ1; Q9H782; Q9NWU9; Q9P0Q2; Q9Y5A8"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"1"	"352.4"	"254.4"	"304.2"	"296.1"	"277.9"	"279.1"	"641.4"	"18.1"	"5186.0"	"5076.8"	"12460.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62258"	"14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1"	"0.000"	""	"54"	"11"	"25"	"9"	"255"	"29.2"	"4.74"	"6165.60"	"41.72"	"10"	"10"	"stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7531"	"ENSG00000108953; ENSG00000274474"	"YWHAE"	"B3KY71; D3DTH5; hsa:7531; P29360; P42655; P62258; Q4VJB6; Q53XZ5; Q63631; Q7M4R4"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria ; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Regulation of HSF1-mediated heat shock response; Signaling by Hippo; HSF1 activation; NADE modulates death signalling"	"Cell cycle; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Calcium regulation in cardiac cells; 17p13.3 (YWHAE) copy number variation; Sudden infant death syndrome (SIDS) susceptibility pathways"	"26"	"0"	"670.9"	"498.8"	"640.5"	"641.7"	"610.8"	"540.4"	"1369.9"	"14.3"	"4800.0"	"4610.4"	"8572.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01970"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens OX=9606 GN=PLCB3 PE=1 SV=2"	"0.000"	""	"12"	"10"	"16"	"10"	"1234"	"138.7"	"5.90"	"2640.50"	"41.70"	"6"	"10"	"other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf08703, Pf09279, Pf17787"	"5331"	"ENSG00000149782"	"PLCB3"	"A5PKZ6; G5E960; hsa:5331; Q01970; Q8N1A4"	"G alpha (q) signalling events; Ca2+ pathway; G beta:gamma signalling through PLC beta; Presynaptic function of Kainate receptors; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion; Synthesis of IP3 and IP4 in the cytosol; PLC beta mediated events; Acetylcholine regulates insulin secretion"	"Alzheimer's disease and miRNA effects; S1P receptor signal transduction; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; GPR40 pathway; MAPK cascade; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Hippo signaling regulation pathways; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; Calcium regulation in cardiac cells"	"26"	"0"	"115.4"	"83.0"	"127.8"	"118.1"	"130.5"	"127.9"	"230.5"	"11.7"	"2572.1"	"2518.9"	"5601.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CT7"	"Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1"	"0.000"	""	"55"	"13"	"24"	"13"	"223"	"25.8"	"9.54"	"4242.46"	"41.64"	"10"	"12"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06244"	"115098"	"ENSG00000007080"	"CCDC124"	"hsa:115098; Q96CT7"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"467.1"	"373.8"	"503.0"	"473.4"	"420.1"	"529.6"	"857.4"	"7.8"	"6350.1"	"6422.6"	"12278.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ13"	"Leucine-rich repeat protein SHOC-2 OS=Homo sapiens OX=9606 GN=SHOC2 PE=1 SV=2"	"0.000"	""	"23"	"10"	"15"	"10"	"582"	"64.8"	"8.46"	"1250.15"	"41.59"	"3"	"10"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13855"	"8036"	"ENSG00000108061"	"SHOC2"	"A8K9W8; B3KR23; hsa:8036; O76063; Q5VZS8; Q5VZS9; Q9UQ13"	"RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling"	"Ras signaling; 22q11.2 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma"	"6"	"0"	"303.1"	"228.4"	"299.7"	"286.0"	"284.2"	"276.6"	"401.4"	"2.1"	"3802.3"	"4017.1"	"8579.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UE4"	"Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2"	"0.000"	""	"23"	"11"	"23"	"11"	"582"	"63.8"	"9.32"	"3822.32"	"41.55"	"9"	"11"	"signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15686"	"92140"	"ENSG00000147649"	"MTDH"	"hsa:92140; Q05DH2; Q52QU9; Q6PK07; Q86UE4; Q8TCX3"	""	"Gastric cancer network 2; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; CCL18 signaling pathway"	"3"	"0"	"250.4"	"229.0"	"247.2"	"250.8"	"264.9"	"264.7"	"486.5"	"7.4"	"4675.6"	"5281.0"	"8321.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07955"	"Serine/arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2"	"0.000"	""	"44"	"11"	"22"	"11"	"248"	"27.7"	"10.36"	"3514.77"	"41.52"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6426"	"ENSG00000136450"	"SRSF1"	"B2R6Z7; D3DTZ3; hsa:6426; Q07955; Q13809"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"7"	"0"	"1266.3"	"1209.8"	"907.4"	"1001.1"	"870.6"	"950.2"	"2150.5"	"2.1"	"3411.5"	"3489.8"	"5144.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96I25"	"Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1"	"0.000"	""	"32"	"11"	"27"	"10"	"401"	"44.9"	"5.97"	"3897.86"	"41.38"	"10"	"10"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf01585"	"84991"	"ENSG00000134453"	"RBM17"	"hsa:84991; Q96GY6; Q96I25"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"1"	"180.2"	"123.4"	"180.9"	"183.4"	"199.3"	"167.9"	"281.9"	"9.7"	"2949.1"	"3233.4"	"7555.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWY3"	"U4/U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2"	"0.000"	""	"28"	"12"	"18"	"12"	"499"	"55.4"	"5.78"	"2653.14"	"41.23"	"7"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf09785"	"26121"	"ENSG00000105618; ENSG00000274144; ENSG00000274651; ENSG00000274894; ENSG00000275117; ENSG00000275885; ENSG00000276421; ENSG00000277154; ENSG00000277707; ENSG00000277953"	"PRPF31"	"E7ESA8; F1T0A4; F1T0A5; hsa:26121; Q17RB4; Q8N7F9; Q8WWY3; Q9H271; Q9Y439"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"831.2"	"535.0"	"667.7"	"682.3"	"568.9"	"639.9"	"1445.8"	"10.9"	"4501.9"	"4443.8"	"9755.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AG4"	"Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1"	"0.000"	""	"32"	"8"	"18"	"8"	"307"	"34.9"	"9.57"	"3019.46"	"41.22"	"6"	"7"	""	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	""	"Pf13855"	"55379"	"ENSG00000108829"	"LRRC59"	"B2RE83; D3DTX8; hsa:55379; Q96AG4; Q9P189"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"313.8"	"292.0"	"291.4"	"266.3"	"269.1"	"305.9"	"682.2"	"3.9"	"4714.6"	"4852.0"	"11217.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06124"	"Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3"	"0.000"	""	"25"	"11"	"21"	"11"	"593"	"68.0"	"7.30"	"3798.75"	"41.20"	"10"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00102"	"5781"	"ENSG00000179295"	"PTPN11"	"A8K1D9; hsa:5781; Q06124; Q96HD7"	"PIP3 activates AKT signaling; GPVI-mediated activation cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Platelet sensitization by LDL; CTLA4 inhibitory signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Interleukin-3, Interleukin-5 and GM-CSF signaling; PD-1 signaling; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Signal regulatory protein family interactions; Constitutive Signaling by Aberrant PI3K in Cancer; RET signaling; PI3K Cascade; Signaling by SCF-KIT; Downstream signal transduction; Tie2 Signaling; Interleukin-6 signaling; Signaling by Leptin; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Signaling by CSF3 (G-CSF); GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; PI-3K cascade:FGFR4; Activated NTRK2 signals through FRS2 and FRS3; Spry regulation of FGF signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; Prolactin receptor signaling; Interleukin-20 family signaling; Netrin mediated repulsion signals; Interleukin-37 signaling; PECAM1 interactions; MET activates PTPN11; STAT5 activation downstream of FLT3 ITD mutants; Regulation of RUNX1 Expression and Activity; STAT5 Activation"	"IL-5 signaling pathway; Heart development; IL-1 signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; IL-4 signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Cancer immunotherapy by CTLA4 blockade; Cancer immunotherapy by PD-1 blockade; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Insulin signaling; IL-2 signaling pathway; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Orexin receptor pathway; GDNF signaling; Interferon type I signaling pathways; Type II interferon signaling; T-cell receptor signaling pathway"	"90"	"0"	"233.6"	"165.3"	"253.9"	"258.7"	"235.1"	"229.6"	"370.9"	"1.3"	"3641.7"	"3461.6"	"6159.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12959"	"Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2"	"0.000"	""	"15"	"11"	"20"	"10"	"904"	"100.4"	"5.76"	"3889.98"	"41.10"	"10"	"10"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00018, Pf00595, Pf00625, Pf09058, Pf10600, Pf10608"	"1739"	"ENSG00000075711"	"DLG1"	"A5YKK7; B4DGU1; B4DGZ8; B7ZMM0; B9EIQ5; D3DXB8; D3DXB9; E7EWL7; E9PG21; hsa:1739; Q12958; Q12959"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Disruption of postsynaptic signaling by CNV; 3q29 copy number variation syndrome"	"14"	"1"	"142.9"	"110.2"	"159.9"	"129.5"	"140.5"	"144.8"	"259.4"	"10.4"	"2982.6"	"2993.2"	"5165.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99615"	"DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2"	"0.000"	""	"28"	"13"	"25"	"13"	"494"	"56.4"	"6.96"	"4189.20"	"40.98"	"9"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf13181, Pf13414, Pf13432"	"7266"	"ENSG00000168259"	"DNAJC7"	"hsa:7266; Q7Z784; Q99615"	"Regulation of HSF1-mediated heat shock response"	"Constitutive androstane receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway"	"4"	"0"	"495.1"	"410.4"	"532.1"	"475.6"	"470.6"	"415.3"	"751.8"	"4.7"	"5534.0"	"5934.4"	"10157.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10570"	"Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2"	"0.000"	""	"10"	"12"	"22"	"12"	"1443"	"160.8"	"6.40"	"3541.84"	"40.89"	"10"	"12"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"29894"	"ENSG00000071894; ENSG00000285049"	"CPSF1"	"hsa:29894; Q10570; Q96AF0"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"7"	"0"	"367.1"	"259.1"	"416.2"	"354.4"	"356.5"	"288.9"	"660.0"	"5.2"	"4557.3"	"4359.1"	"9481.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32121"	"Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2"	"0.000"	""	"27"	"10"	"19"	"10"	"409"	"46.1"	"7.69"	"2582.70"	"40.88"	"7"	"9"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00339, Pf02752"	"409"	"ENSG00000141480"	"ARRB2"	"B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; hsa:409; P32121; Q0Z8D3; Q2PP19; Q6ICT3; Q8N7Y2; Q9UEQ6"	"Ub-specific processing proteases; Thrombin signalling through proteinase activated receptors (PARs); Activated NOTCH1 Transmits Signal to the Nucleus; Cargo recognition for clathrin-mediated endocytosis; Activation of SMO; G alpha (s) signalling events; Signaling by BRAF and RAF1 fusions; WNT5A-dependent internalization of FZD4; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Corticotropin-releasing hormone signaling pathway; Complement system; Myometrial relaxation and contraction pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"27"	"0"	"62.7"	"54.9"	"92.8"	"78.3"	"86.1"	"86.9"	"289.0"	"5.7"	"2508.3"	"2667.1"	"3802.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13576"	"Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4"	"0.000"	""	"9"	"12"	"16"	"10"	"1575"	"180.5"	"5.64"	"1498.43"	"40.79"	"5"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"10788"	"ENSG00000145703"	"IQGAP2"	"A8K4V1; B7Z8A4; hsa:10788; J3KR91; Q13576"	"Neutrophil degranulation; RHO GTPases activate IQGAPs; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle"	"Ciliary landscape; G13 signaling pathway"	"7"	"0"	"78.8"	"40.5"	"99.5"	"70.1"	"86.7"	"77.9"	"235.2"	"28.0"	"2842.9"	"2859.1"	"6697.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QC0"	"Serine/threonine-protein phosphatase 1 regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PPP1R10 PE=1 SV=1"	"0.000"	""	"18"	"12"	"18"	"12"	"940"	"99.0"	"9.17"	"3019.82"	"40.78"	"7"	"11"	"transport;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf08711"	"5514"	"ENSG00000204569; ENSG00000206489; ENSG00000227804; ENSG00000230995; ENSG00000231737; ENSG00000235291; ENSG00000238104"	"PPP1R10"	"hsa:5514; O00405; Q96QC0"	""	""	"0"	"0"	"391.0"	"263.7"	"365.3"	"365.6"	"325.6"	"354.8"	"594.8"	"12.3"	"3981.5"	"3954.4"	"9396.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60869"	"Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1"	"0.000"	""	"58"	"10"	"23"	"10"	"148"	"16.4"	"9.95"	"4408.97"	"40.76"	"9"	"8"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01381, Pf08523"	"8721"	"ENSG00000107223"	"EDF1"	"hsa:8721; O60869; Q5T5T2; Q9UIM1"	""	""	"0"	"0"	"790.7"	"842.9"	"1073.5"	"887.0"	"589.4"	"1019.1"	"2676.3"	"7.0"	"7866.9"	"7469.3"	"13637.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16181"	"Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2"	"0.000"	""	"21"	"7"	"19"	"6"	"437"	"50.6"	"8.63"	"4698.88"	"40.65"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00735"	"989"	"ENSG00000122545"	"SEPTIN7"	"hsa:989; Q16181; Q52M76; Q6NX50"	"MAPK6/MAPK4 signaling"	""	"1"	"0"	"219.4"	"147.5"	"251.9"	"230.1"	"219.5"	"192.9"	"453.2"	"1.7"	"2946.9"	"2758.3"	"5063.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51610"	"Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2"	"0.000"	""	"8"	"11"	"18"	"11"	"2035"	"208.6"	"7.46"	"2390.52"	"40.54"	"7"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01344, Pf13415"	"3054"	"ENSG00000172534"	"HCFC1"	"hsa:3054; P51610; Q6P4G5"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Transcriptional activation of mitochondrial biogenesis; HATs acetylate histones"	"Mitochondrial gene expression; Pleural mesothelioma"	"6"	"0"	"280.1"	"242.5"	"314.4"	"275.3"	"265.3"	"300.5"	"557.5"	"4.3"	"2508.3"	"2536.3"	"4959.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43719"	"HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1"	"0.000"	""	"15"	"9"	"18"	"9"	"755"	"85.8"	"4.40"	"3893.60"	"40.49"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00076"	"27336"	"ENSG00000102241"	"HTATSF1"	"D3DWG9; hsa:27336; O43719; Q59G06; Q99730"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"380.2"	"284.7"	"386.2"	"361.6"	"358.5"	"315.6"	"659.8"	"9.9"	"3130.4"	"2936.1"	"7151.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14008"	"Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3"	"0.000"	""	"7"	"12"	"22"	"12"	"2032"	"225.4"	"7.80"	"3959.48"	"40.47"	"10"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"9793"	"ENSG00000175216"	"CKAP5"	"hsa:9793; Q05D70; Q0VAX7; Q0VAX8; Q14008; Q14668; Q2TA89; Q6NSH4"	"Separation of Sister Chromatids; Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"4p16.3 copy number variation"	"14"	"0"	"392.9"	"312.7"	"384.2"	"332.2"	"327.2"	"397.8"	"1169.0"	"10.3"	"3908.8"	"3853.3"	"8075.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14654"	"Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1"	"0.000"	""	"12"	"12"	"19"	"12"	"1257"	"133.7"	"8.44"	"2567.86"	"40.34"	"8"	"11"	"signal transduction"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf02174"	"8471"	"ENSG00000133124"	"IRS4"	"hsa:8471; O14654"	"IRS-related events triggered by IGF1R"	"Alzheimer's disease and miRNA effects; Adipogenesis; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; Insulin signaling; Alzheimer's disease"	"8"	"0"	"401.9"	"321.4"	"356.8"	"368.8"	"337.0"	"326.6"	"688.8"	"4.9"	"4944.5"	"5386.3"	"9781.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99543"	"DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4"	"0.000"	""	"19"	"10"	"18"	"10"	"621"	"72.0"	"8.70"	"2733.25"	"40.24"	"7"	"10"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00226, Pf00249, Pf16717"	"27000"	"ENSG00000105821"	"DNAJC2"	"A4VCI0; hsa:27000; Q99543; Q9BVX1"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"204.7"	"147.3"	"284.0"	"213.7"	"220.5"	"203.7"	"432.3"	"16.3"	"4279.5"	"4247.5"	"8750.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36776"	"Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2"	"0.000"	""	"14"	"11"	"19"	"11"	"959"	"106.4"	"6.39"	"2586.98"	"40.19"	"6"	"11"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf02190, Pf05362"	"9361"	"ENSG00000196365"	"LONP1"	"B3KPH8; D6W635; E5KMH8; F5GZ27; hsa:9361; P36776; P36777; Q8N8K8; Q9UQ95"	""	""	"0"	"0"	"57.4"	"40.1"	"76.1"	"74.2"	"71.9"	"54.9"	"115.6"	"13.6"	"2656.0"	"2870.9"	"6304.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63104"	"14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1"	"0.000"	""	"47"	"11"	"24"	"8"	"245"	"27.7"	"4.79"	"4573.89"	"40.12"	"10"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7534"	"ENSG00000164924"	"YWHAZ"	"A8K1N0; B7Z465; hsa:7534; P29213; P29312; P63104; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33"	"RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Negative regulation of NOTCH4 signaling; Deactivation of the beta-catenin transactivating complex; Interleukin-3, Interleukin-5 and GM-CSF signaling; TP53 Regulates Metabolic Genes; NOTCH4 Activation and Transmission of Signal to the Nucleus; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; Activation of BAD and translocation to mitochondria"	"Cell cycle; Prolactin signaling pathway; Pathogenic Escherichia coli infection; Myometrial relaxation and contraction pathways; Hepatitis B infection; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"23"	"4"	"1611.2"	"1093.2"	"1526.6"	"1555.1"	"1412.0"	"1228.2"	"2180.7"	"12.6"	"6916.1"	"6676.6"	"10829.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5BKZ1"	"DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2"	"0.000"	""	"21"	"10"	"22"	"10"	"582"	"65.6"	"5.15"	"4089.30"	"40.11"	"10"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"284695"	"ENSG00000162664"	"ZNF326"	"A8MYX1; B4DLN0; B4E179; hsa:284695; Q5BKZ1; Q5VW93; Q5VW94; Q5VW96; Q5VW97; Q6NSA2; Q7Z638; Q7Z6C2"	""	""	"0"	"0"	"980.1"	"735.7"	"958.6"	"950.7"	"851.5"	"881.3"	"1837.2"	"1.2"	"3772.9"	"3394.2"	"6554.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16630"	"Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2"	"0.000"	""	"22"	"11"	"21"	"11"	"551"	"59.2"	"7.15"	"4353.44"	"40.06"	"10"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076"	"11052"	"ENSG00000111605"	"CPSF6"	"A8K7K9; hsa:11052; Q16630; Q53ES1; Q9BSJ7; Q9BW18"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	""	"2"	"0"	"239.2"	"199.5"	"239.0"	"219.2"	"200.4"	"200.9"	"433.5"	"11.4"	"3815.0"	"4104.4"	"7752.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71DI3"	"Histone H3.2 OS=Homo sapiens OX=9606 GN=H3C15 PE=1 SV=3"	"0.000"	""	"63"	"9"	"21"	"1"	"136"	"15.4"	"11.27"	"3441.10"	"40.00"	"8"	"7"	"cell organization and biogenesis"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"126961; 333932; 653604"	"ENSG00000183598; ENSG00000203811; ENSG00000203852"	"H3C13; H3C14; H3C15"	"A2BDF6; A6NFS4; hsa:126961; hsa:333932; hsa:653604; Q6B053; Q71DI3"	"Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis; RMTs methylate histone arginines; Interleukin-7 signaling; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; PKMTs methylate histone lysines"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"36"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55209"	"Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1"	"0.000"	""	"28"	"8"	"19"	"6"	"391"	"45.3"	"4.46"	"2941.37"	"39.99"	"6"	"7"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4673"	"ENSG00000187109"	"NAP1L1"	"B3KNT8; B3KV44; hsa:4673; P55209"	""	"VEGFA-VEGFR2 signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"2"	"2"	"102.4"	"86.0"	"121.3"	"107.4"	"111.5"	"90.5"	"362.8"	"28.3"	"2650.3"	"2450.0"	"4682.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09028"	"Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3"	"0.000"	""	"29"	"11"	"20"	"5"	"425"	"47.6"	"4.89"	"3114.57"	"39.71"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5928"	"ENSG00000162521"	"RBBP4"	"B2R6G9; B4DRH0; D3DPQ3; hsa:5928; P31149; Q09028; Q53H02; Q96BV9"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; HCMV Early Events; RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; HDACs deacetylate histones; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"28"	"6"	"521.4"	"405.8"	"504.6"	"494.2"	"494.0"	"410.0"	"852.8"	"8.3"	"4230.5"	"4193.0"	"8601.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13616"	"Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2"	"0.000"	""	"16"	"11"	"16"	"11"	"776"	"89.6"	"8.00"	"2478.44"	"39.54"	"7"	"9"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8454"	"ENSG00000055130"	"CUL1"	"D3DWG3; hsa:8454; O60719; Q08AL6; Q13616; Q8IYW1"	"Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Circadian Clock; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Pleural mesothelioma; Notch signaling pathway"	"40"	"0"	"139.8"	"101.3"	"154.2"	"140.9"	"145.8"	"159.8"	"257.2"	"7.6"	"3874.3"	"4095.3"	"6921.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23921"	"Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1"	"0.000"	""	"17"	"9"	"16"	"9"	"792"	"90.0"	"7.15"	"2691.45"	"39.50"	"7"	"9"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00317, Pf02867, Pf03477"	"6240"	"ENSG00000167325"	"RRM1"	"hsa:6240; P23921; Q9UNN2"	"Interconversion of nucleotide di- and triphosphates"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Pyrimidine metabolism"	"4"	"0"	"84.3"	"76.9"	"74.2"	"86.3"	"99.2"	"82.9"	"219.2"	"7.0"	"2649.2"	"2803.5"	"4922.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUQ3"	"Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2"	"0.000"	""	"27"	"11"	"20"	"11"	"528"	"60.5"	"7.52"	"3841.73"	"39.49"	"9"	"10"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf09728"	"55787"	"ENSG00000086712"	"TXLNG"	"hsa:55787; Q2KQ75; Q5JNZ7; Q9NUQ3; Q9P0X1"	""	""	"0"	"0"	"295.2"	"230.0"	"290.5"	"270.5"	"297.8"	"272.9"	"501.1"	"9.9"	"4175.2"	"4205.6"	"8684.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75934"	"Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1"	"0.000"	""	"40"	"9"	"19"	"9"	"225"	"26.1"	"5.66"	"3694.74"	"39.41"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05700"	"10286"	"ENSG00000116752"	"BCAS2"	"hsa:10286; O75934; Q6FGS0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"118.5"	"79.9"	"144.9"	"119.5"	"106.2"	"111.0"	"270.7"	"12.6"	"3349.6"	"3437.5"	"6350.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11586"	"C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=3"	"0.000"	""	"13"	"10"	"20"	"10"	"935"	"101.5"	"7.30"	"3402.26"	"39.36"	"7"	"9"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"199.7"	"162.4"	"201.1"	"181.9"	"176.2"	"166.5"	"422.8"	"12.4"	"2169.4"	"2172.6"	"4725.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26641"	"Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3"	"0.000"	""	"29"	"13"	"25"	"13"	"437"	"50.1"	"6.67"	"4176.67"	"39.14"	"12"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf00043, Pf00647, Pf02798"	"1937"	"ENSG00000254772"	"EEF1G"	"B4DTG2; hsa:1937; P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196"	"Signaling by ALK fusions and activated point mutants; Eukaryotic Translation Elongation"	"Translation factors"	"3"	"0"	"776.3"	"597.1"	"788.4"	"664.4"	"677.9"	"633.9"	"1014.0"	"18.3"	"6800.2"	"7286.3"	"11233.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15334"	"Lethal(2) giant larvae protein homolog 1 OS=Homo sapiens OX=9606 GN=LLGL1 PE=1 SV=3"	"0.000"	""	"13"	"10"	"17"	"10"	"1064"	"115.3"	"6.29"	"3756.78"	"39.12"	"8"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366"	"3996"	"ENSG00000131899; ENSG00000284137"	"LLGL1"	"A7MBM7; hsa:3996; O00188; Q15334; Q58F11; Q86UK6"	""	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"1"	"0"	"170.8"	"105.5"	"187.1"	"162.5"	"161.3"	"146.2"	"287.5"	"17.8"	"4099.1"	"4078.4"	"7483.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86V81"	"THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3"	"0.000"	""	"48"	"7"	"13"	"7"	"257"	"26.9"	"11.15"	"1748.20"	"39.10"	"4"	"6"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf13865"	"10189"	""	"ALYREF"	"hsa:10189; O43672; Q86V81"	"mRNA Splicing - Major Pathway; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"7"	"0"	"489.4"	"423.6"	"463.7"	"420.4"	"392.0"	"409.4"	"1799.5"	"4.8"	"3108.9"	"3172.7"	"4569.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29401"	"Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3"	"0.000"	""	"17"	"7"	"15"	"7"	"623"	"67.8"	"7.66"	"3094.69"	"39.07"	"5"	"6"	"other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00456, Pf02779, Pf02780"	"7086"	"ENSG00000163931"	"TKT"	"A8K089; B4DE31; E7EPA7; hsa:7086; P29401; Q8TBA3; Q96HH3"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate"	"Pentose phosphate metabolism; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways"	"7"	"0"	"63.9"	"42.1"	"82.7"	"65.3"	"78.7"	"77.0"	"154.0"	"21.9"	"1819.8"	"1864.1"	"5752.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42704"	"Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3"	"0.000"	""	"9"	"11"	"20"	"11"	"1394"	"157.8"	"6.13"	"3101.14"	"38.99"	"9"	"11"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01535"	"10128"	"ENSG00000138095"	"LRPPRC"	"A0PJE3; A8K1V1; hsa:10128; P42704; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Ciliary landscape"	"4"	"0"	"352.5"	"312.4"	"404.1"	"332.9"	"367.9"	"350.6"	"679.2"	"13.1"	"4094.7"	"4355.2"	"8063.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11310"	"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADM PE=1 SV=1"	"0.000"	""	"31"	"8"	"15"	"8"	"421"	"46.6"	"8.37"	"3179.32"	"38.93"	"6"	"8"	"other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"34"	"ENSG00000117054"	"ACADM"	"hsa:34; P11310; Q5T4U4; Q9NYF1"	"PPARA activates gene expression; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; PPAR signaling pathway; Mitochondrial fatty acid oxidation disorders; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"13"	"0"	"59.4"	"39.0"	"85.5"	"60.4"	"80.3"	"85.4"	"112.7"	"9.1"	"2094.6"	"2136.8"	"4741.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTL8"	"Pre-mRNA-splicing factor 38B OS=Homo sapiens OX=9606 GN=PRPF38B PE=1 SV=1"	"0.000"	""	"14"	"7"	"17"	"7"	"546"	"64.4"	"10.54"	"3024.35"	"38.92"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371"	"55119"	"ENSG00000134186"	"PRPF38B"	"hsa:55119; Q05DD6; Q32Q58; Q5VTL8; Q5VTL9; Q6PK39; Q7Z6E2; Q86WF3; Q8IWG9; Q9NW40"	""	""	"0"	"0"	"218.3"	"176.5"	"220.6"	"229.8"	"191.6"	"222.0"	"447.1"	"15.4"	"2668.5"	"2757.7"	"6214.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUM0"	"Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2"	"0.000"	""	"11"	"11"	"21"	"11"	"1156"	"128.9"	"5.10"	"5178.46"	"38.89"	"10"	"10"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf03177"	"55746"	"ENSG00000069248"	"NUP133"	"B2RAZ8; hsa:55746; Q5T8N0; Q8WUM0; Q9H9W2; Q9NV71; Q9NVC4"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"Ciliary landscape"	"36"	"0"	"495.1"	"379.4"	"401.0"	"408.6"	"402.9"	"375.2"	"525.4"	"9.1"	"3092.1"	"3031.5"	"6289.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16531"	"DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1"	"0.000"	""	"11"	"13"	"18"	"13"	"1140"	"126.9"	"5.26"	"1488.46"	"38.79"	"5"	"13"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"1642"	"ENSG00000167986"	"DDB1"	"A6NG77; B2R648; B4DG00; hsa:1642; O15176; Q13289; Q16531; Q58F96"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"Hippo-Merlin signaling dysregulation; Hepatitis B infection; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"14"	"0"	"363.5"	"277.5"	"349.0"	"327.5"	"310.4"	"310.6"	"611.6"	"21.7"	"5327.1"	"5531.0"	"12814.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14684"	"Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3"	"0.000"	""	"17"	"10"	"16"	"10"	"758"	"84.4"	"9.76"	"2839.74"	"38.79"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05997"	"23076"	"ENSG00000160208"	"RRP1B"	"hsa:23076; Q14684; Q8TBZ4"	""	""	"0"	"0"	"133.8"	"114.5"	"142.3"	"148.5"	"136.4"	"148.5"	"477.1"	"1.0"	"2385.2"	"2376.9"	"4754.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTR2"	"E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2"	"0.000"	""	"11"	"9"	"19"	"7"	"975"	"113.6"	"5.94"	"3690.67"	"38.75"	"8"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"56254"	"ENSG00000155827"	"RNF20"	"A7MCT5; hsa:56254; Q2TB34; Q5VTR2; Q69YL5; Q6P527; Q8N3J4; Q96JD3; Q9H9Y7; Q9HA51; Q9NUR4; Q9NWQ3; Q9NX83"	"E3 ubiquitin ligases ubiquitinate target proteins; RHOBTB1 GTPase cycle"	"ATM signaling in development and disease"	"3"	"2"	"229.0"	"169.7"	"220.2"	"202.3"	"174.0"	"178.1"	"366.7"	"7.8"	"2549.5"	"2548.4"	"4713.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15344"	"E3 ubiquitin-protein ligase Midline-1 OS=Homo sapiens OX=9606 GN=MID1 PE=1 SV=1"	"0.000"	""	"17"	"9"	"14"	"8"	"667"	"75.2"	"6.80"	"2508.13"	"38.67"	"6"	"8"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00041, Pf00622, Pf00643, Pf13445, Pf13765, Pf18568"	"4281"	"ENSG00000101871"	"MID1"	"B2RCG2; hsa:4281; O15344; O75361; Q9BZX5"	"Interferon gamma signaling"	""	"1"	"1"	"113.4"	"76.5"	"130.3"	"119.9"	"110.6"	"97.9"	"252.7"	"9.6"	"2190.9"	"2049.9"	"4036.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62136"	"Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1"	"0.000"	""	"28"	"8"	"17"	"3"	"330"	"37.5"	"6.33"	"3361.13"	"38.64"	"7"	"8"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5499"	"ENSG00000172531"	"PPP1CA"	"A6NNR3; B2R908; hsa:5499; P08129; P20653; P22802; P62136; Q07161"	"Triglyceride catabolism; Circadian Clock; Downregulation of TGF-beta receptor signaling; DARPP-32 events"	"Sphingolipid pathway; Nicotine effect on dopaminergic neurons; Common pathways underlying drug addiction; Focal adhesion; VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Netrin-UNC5B signaling pathway; Neuroinflammation and glutamatergic signaling"	"13"	"5"	"353.1"	"268.0"	"372.9"	"388.8"	"358.5"	"307.8"	"676.3"	"12.3"	"3648.2"	"3548.7"	"7420.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99986"	"Serine/threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1"	"0.000"	""	"16"	"8"	"14"	"8"	"396"	"45.4"	"8.91"	"2131.11"	"38.64"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus"	"kinase activity;other molecular function"	"Pf00069"	"7443"	"ENSG00000100749"	"VRK1"	"hsa:7443; Q3SYL2; Q99986"	"Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	""	"2"	"0"	"236.8"	"235.4"	"323.4"	"277.7"	"281.7"	"262.3"	"611.0"	"10.4"	"4778.8"	"3970.1"	"11003.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35232"	"Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1"	"0.000"	""	"40"	"11"	"22"	"11"	"272"	"29.8"	"5.76"	"4641.75"	"38.58"	"9"	"10"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"5245"	"ENSG00000167085"	"PHB1"	"B4DY47; hsa:5245; P35232; Q4VBQ0"	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Processing of SMDT1"	""	"5"	"0"	"577.1"	"474.8"	"560.3"	"493.2"	"430.9"	"570.7"	"1029.1"	"3.2"	"4395.4"	"4528.6"	"7351.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42356"	"Phosphatidylinositol 4-kinase alpha OS=Homo sapiens OX=9606 GN=PI4KA PE=1 SV=4"	"0.000"	""	"6"	"10"	"16"	"10"	"2102"	"236.7"	"7.06"	"2893.77"	"38.54"	"7"	"9"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf19274"	"5297"	"ENSG00000241973"	"PI4KA"	"hsa:5297; P42356; Q7Z625; Q9UPG2"	"Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the ER membrane"	"Ectoderm differentiation; 22q11.2 copy number variation syndrome"	"4"	"0"	"57.5"	"49.3"	"73.8"	"70.2"	"74.8"	"59.3"	"141.8"	"12.9"	"1695.5"	"1638.6"	"3703.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15056"	"Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5"	"0.000"	""	"48"	"9"	"17"	"9"	"248"	"27.4"	"7.23"	"2791.50"	"38.41"	"6"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7458"	"ENSG00000106682"	"EIF4H"	"A8K3R1; D3DXF6; D3DXF8; hsa:7458; Q15056"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"Translation factors; 7q11.23 copy number variation syndrome"	"7"	"0"	"115.0"	"87.4"	"110.7"	"116.0"	"107.8"	"128.2"	"212.5"	"14.0"	"2742.9"	"2774.9"	"4286.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52948"	"Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4"	"0.000"	""	"9"	"13"	"26"	"13"	"1817"	"197.5"	"6.40"	"4613.05"	"38.41"	"12"	"11"	"cell organization and biogenesis;protein metabolism;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04096, Pf12110"	"4928"	"ENSG00000110713"	"NUP98"	"hsa:4928; P52948; Q8IUT2; Q8WYB0; Q96E54; Q9H3Q4; Q9NT02; Q9UF57; Q9UHX0; Q9Y6J4; Q9Y6J5"	""	"SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"1"	"0"	"754.5"	"571.7"	"619.4"	"633.8"	"596.7"	"648.7"	"869.8"	"6.6"	"3192.7"	"3170.1"	"5622.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92922"	"SWI/SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3"	"0.000"	""	"10"	"9"	"16"	"8"	"1105"	"122.8"	"5.76"	"1602.10"	"38.23"	"5"	"9"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6599"	"ENSG00000173473"	"SMARCC1"	"hsa:6599; Q17RS0; Q6P172; Q8IWH2; Q92922"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"6"	"0"	"273.0"	"196.3"	"264.2"	"256.7"	"227.5"	"249.5"	"445.6"	"7.4"	"3117.4"	"3251.6"	"6146.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46060"	"Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1"	"0.000"	""	"19"	"10"	"20"	"10"	"587"	"63.5"	"4.68"	"3235.65"	"38.10"	"9"	"10"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07834, Pf13516"	"5905"	"ENSG00000100401"	"RANGAP1"	"hsa:5905; P46060; Q96JJ2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation; SUMOylation of nuclear envelope proteins"	"22q11.2 copy number variation syndrome; IL-18 signaling pathway"	"12"	"0"	"314.6"	"229.4"	"337.4"	"321.4"	"304.7"	"285.4"	"537.6"	"16.0"	"3009.5"	"3097.5"	"5668.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05114"	"Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3"	"0.000"	""	"61"	"7"	"18"	"7"	"100"	"10.7"	"9.60"	"2739.53"	"38.01"	"5"	"6"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3150"	"ENSG00000205581"	"HMGN1"	"hsa:3150; P05114; Q3KQR8"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"ATM signaling in development and disease ; p38 MAPK signaling pathway; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"8"	"0"	"355.4"	"319.9"	"367.6"	"360.6"	"433.0"	"390.9"	"556.0"	"11.3"	"4376.0"	"4449.3"	"8645.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13995"	"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2"	"0.000"	""	"29"	"9"	"13"	"9"	"350"	"37.9"	"8.73"	"1583.09"	"38.00"	"4"	"8"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00763, Pf02882"	"10797"	"ENSG00000065911"	"MTHFD2"	"hsa:10797; P13995; Q53G90; Q53GV5; Q53S36; Q7Z650"	"Metabolism of folate and pterines"	"Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"4"	"0"	"162.9"	"103.8"	"232.2"	"178.1"	"190.6"	"176.4"	"349.8"	"13.3"	"2367.6"	"2292.3"	"5087.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08170"	"Serine/arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2"	"0.000"	""	"17"	"9"	"24"	"5"	"494"	"56.6"	"11.52"	"3901.39"	"37.78"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6429"	"ENSG00000116350"	"SRSF4"	"hsa:6429; Q08170; Q5VXP1; Q9BUA4; Q9UEB5"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"mRNA processing"	"6"	"5"	"1885.4"	"1344.3"	"1878.5"	"1763.1"	"1502.7"	"1262.0"	"2676.8"	"1.7"	"5388.7"	"5269.6"	"10279.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12904"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2"	"0.000"	""	"35"	"10"	"17"	"10"	"312"	"34.3"	"8.43"	"2838.78"	"37.69"	"6"	"9"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01588"	"9255"	"ENSG00000164022"	"AIMP1"	"B3KTR2; B4E1S7; hsa:9255; Q12904; Q6FG28; Q96CQ9"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Ciliary landscape"	"3"	"0"	"187.7"	"112.7"	"197.5"	"165.8"	"180.4"	"159.2"	"328.4"	"15.9"	"5239.6"	"5311.8"	"12360.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84103"	"Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1"	"0.000"	""	"41"	"6"	"15"	"6"	"164"	"19.3"	"11.65"	"1985.70"	"37.65"	"3"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6428"	"ENSG00000112081"	"SRSF3"	"B4E241; hsa:6428; O08831; P23152; P84103; Q5R3K0"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"0"	"570.8"	"437.3"	"472.2"	"475.0"	"366.4"	"332.1"	"1555.1"	"6.0"	"3302.2"	"3306.5"	"5871.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31942"	"Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2"	"0.000"	""	"23"	"8"	"19"	"7"	"346"	"36.9"	"6.87"	"3524.07"	"37.56"	"5"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"3189"	"ENSG00000096746"	"HNRNPH3"	"A8K682; B3KRE1; hsa:3189; P31942; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4; Q9UFU4; Q9Y4J5"	""	""	"0"	"0"	"151.7"	"111.4"	"153.2"	"138.7"	"135.4"	"157.0"	"324.1"	"1.9"	"1309.2"	"1262.5"	"2540.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96E11"	"Ribosome-recycling factor, mitochondrial OS=Homo sapiens OX=9606 GN=MRRF PE=1 SV=1"	"0.000"	""	"40"	"7"	"12"	"7"	"262"	"29.3"	"9.79"	"2213.69"	"37.30"	"5"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity"	"Pf01765"	"92399"	"ENSG00000148187"	"MRRF"	"A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; hsa:92399; Q5RKT1; Q5T7T0; Q5T7T1; Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5; Q96E11"	"Mitochondrial translation termination"	""	"1"	"0"	"123.2"	"105.3"	"171.9"	"119.2"	"130.0"	"165.4"	"273.8"	"11.6"	"2216.2"	"2073.8"	"4800.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13838"	"Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1"	"0.000"	""	"23"	"10"	"19"	"4"	"428"	"49.0"	"5.67"	"2825.46"	"37.16"	"7"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"7919"	"ENSG00000198563; ENSG00000215425; ENSG00000225073; ENSG00000225859; ENSG00000229496; ENSG00000230624; ENSG00000235439"	"DDX39B"	"B0S8C0; hsa:7919; O43496; Q0EFA1; Q13838; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66; Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6; Q5STU8; Q71V76"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RHOBTB2 GTPase cycle"	""	"5"	"5"	"215.5"	"194.6"	"280.3"	"228.6"	"209.9"	"200.4"	"446.1"	"6.9"	"3004.4"	"2967.4"	"7733.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUU7"	"ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1"	"0.000"	""	"23"	"8"	"16"	"2"	"478"	"53.9"	"6.58"	"3062.60"	"36.92"	"6"	"8"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"55308"	"ENSG00000168872"	"DDX19A"	"B2RPL0; B4DRZ7; hsa:55308; Q53FM0; Q9NUU7"	""	""	"0"	"5"	"97.2"	"87.0"	"135.2"	"116.1"	"128.7"	"109.2"	"562.8"	"6.8"	"2408.7"	"2302.0"	"4724.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSJ8"	"Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1"	"0.000"	""	"13"	"10"	"16"	"10"	"1104"	"122.8"	"5.83"	"2230.44"	"36.86"	"6"	"8"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00168, Pf17047"	"23344"	"ENSG00000139641"	"ESYT1"	"A0FGR7; A8K2S2; hsa:23344; O94848; Q6PJN4; Q9BSJ8; Q9H6J1; Q9H6W2; Q9Y416"	"RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Glycosphingolipid metabolism; RHOF GTPase cycle"	""	"7"	"0"	"68.4"	"37.9"	"103.3"	"108.0"	"151.0"	"198.1"	"399.9"	"4.4"	"3399.1"	"3609.7"	"6497.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N684"	"Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1"	"0.000"	""	"17"	"8"	"16"	"8"	"471"	"52.0"	"8.00"	"3350.27"	"36.85"	"6"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79869"	"ENSG00000149532"	"CPSF7"	"B3KU04; C9K0Q4; hsa:79869; Q7Z3H9; Q8N684; Q9H025; Q9H9V1"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; RHOBTB1 GTPase cycle"	""	"5"	"0"	"589.8"	"489.4"	"504.6"	"470.5"	"440.9"	"513.6"	"957.0"	"8.6"	"3807.3"	"3726.9"	"7541.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13645"	"Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6"	"0.000"	""	"21"	"10"	"19"	"7"	"584"	"58.8"	"5.21"	"3257.78"	"36.83"	"9"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038"	"3858"	"ENSG00000186395"	"KRT10"	"hsa:3858; P13645; Q14664; Q8N175"	"Formation of the cornified envelope"	""	"2"	"2"	"337.1"	"359.2"	"274.3"	"610.5"	"311.5"	"940.1"	"798.5"	"2.9"	"2869.9"	"3430.5"	"3361.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZZ5"	"Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3"	"0.000"	""	"27"	"12"	"20"	"12"	"524"	"59.0"	"7.34"	"4081.49"	"36.83"	"9"	"9"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05918"	"8539"	"ENSG00000166181"	"API5"	"B4DGR0; B4DRJ2; B4E283; D3DR21; G3V1C3; hsa:8539; O15441; Q9BZZ5; Q9Y4J7"	""	""	"0"	"0"	"414.9"	"327.3"	"447.5"	"396.8"	"371.0"	"426.6"	"809.5"	"13.0"	"4345.1"	"4458.5"	"9605.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB8"	"Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2"	"0.000"	""	"10"	"9"	"20"	"9"	"1091"	"126.2"	"6.99"	"4090.30"	"36.75"	"7"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"79677"	"ENSG00000163029"	"SMC6"	"A8K8Q6; D6W518; hsa:79677; Q05BV4; Q96SB8; Q9H0X3; Q9H6M0"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"149.6"	"129.4"	"163.2"	"144.2"	"141.4"	"155.4"	"419.0"	"14.0"	"3034.9"	"3006.6"	"7297.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41227"	"N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1"	"0.000"	""	"38"	"6"	"10"	"6"	"235"	"26.4"	"5.64"	"1842.37"	"36.61"	"2"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"8260"	"ENSG00000102030"	"NAA10"	"A6NM98; hsa:8260; P41227"	""	""	"0"	"0"	"38.0"	"26.5"	"41.5"	"40.5"	"57.2"	"46.1"	"85.4"	"9.0"	"2651.6"	"3012.1"	"6398.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38919"	"Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4"	"0.000"	""	"21"	"10"	"21"	"10"	"411"	"46.8"	"6.73"	"5051.39"	"36.58"	"10"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"9775"	"ENSG00000141543"	"EIF4A3"	"hsa:9775; P38919; Q15033; Q6IBQ2; Q96A18"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"TAR syndrome"	"9"	"0"	"449.5"	"375.0"	"490.8"	"422.4"	"388.5"	"422.5"	"1143.0"	"15.0"	"5771.2"	"6327.9"	"13915.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61247"	"40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2"	"0.000"	""	"43"	"12"	"23"	"12"	"264"	"29.9"	"9.73"	"3903.18"	"36.58"	"10"	"10"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01015"	"6189"	"ENSG00000145425"	"RPS3A"	"B2R4D4; D3DP05; hsa:6189; P33443; P49241; P61247"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"1065.8"	"998.3"	"1002.7"	"971.1"	"940.4"	"993.8"	"2344.9"	"28.2"	"6267.8"	"6223.6"	"10622.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15022"	"Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3"	"0.000"	""	"10"	"6"	"13"	"6"	"739"	"83.0"	"8.81"	"2264.69"	"36.52"	"3"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf09733"	"23512"	"ENSG00000178691"	"SUZ12"	"hsa:23512; Q15022; Q96BD9"	"HCMV Early Events; SUMOylation of chromatin organization proteins; Oxidative Stress Induced Senescence; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines"	"Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"14"	"0"	"40.3"	"29.4"	"43.0"	"43.9"	"47.5"	"38.6"	"80.2"	"7.3"	"840.7"	"789.2"	"1780.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24534"	"Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3"	"0.000"	""	"59"	"11"	"21"	"9"	"225"	"24.7"	"4.67"	"3976.58"	"36.48"	"9"	"8"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf00736, Pf10587"	"1933"	"ENSG00000114942; ENSG00000283391"	"EEF1B2"	"A8K795; hsa:1933; P24534; Q6IBH9"	"Eukaryotic Translation Elongation"	"Translation factors"	"2"	"2"	"922.0"	"634.2"	"788.8"	"765.9"	"820.4"	"659.7"	"1085.7"	"7.2"	"6793.3"	"6973.9"	"11278.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43395"	"U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2"	"0.000"	""	"18"	"9"	"17"	"9"	"683"	"77.5"	"9.50"	"3057.47"	"36.46"	"8"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01480, Pf06544, Pf08572"	"9129"	"ENSG00000117360"	"PRPF3"	"B4DSY9; hsa:9129; O43395; O43446; Q5VT54"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"429.1"	"295.7"	"342.4"	"346.1"	"339.0"	"321.2"	"563.4"	"0.5"	"2935.3"	"2941.7"	"6371.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23396"	"40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2"	"0.000"	""	"49"	"9"	"16"	"9"	"243"	"26.7"	"9.66"	"2878.87"	"36.42"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00189, Pf07650"	"6188"	"ENSG00000149273"	"RPS3"	"B2R7N5; hsa:6188; J3KN86; P23396; Q498B5; Q8NI95"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"155.0"	"139.1"	"157.1"	"137.9"	"158.6"	"130.5"	"361.8"	"9.4"	"2111.8"	"2320.7"	"5637.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15555"	"Microtubule-associated protein RP/EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1"	"0.000"	""	"25"	"6"	"16"	"6"	"327"	"37.0"	"5.57"	"2429.57"	"36.37"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"10982"	"ENSG00000166974"	"MAPRE2"	"B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6; hsa:10982; Q15555; Q9UQ33"	""	"Ciliary landscape"	"1"	"0"	"93.1"	"70.6"	"115.5"	"117.2"	"98.7"	"145.7"	"181.2"	"10.0"	"3207.7"	"3406.3"	"7214.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35268"	"60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2"	"0.000"	""	"59"	"7"	"14"	"6"	"128"	"14.8"	"9.19"	"2167.91"	"36.25"	"6"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01776"	"6146"	"ENSG00000116251"	"RPL22"	"B2R495; hsa:6146; P35268; Q6IBD1"	"SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"107.4"	"91.7"	"106.2"	"104.8"	"84.7"	"94.2"	"266.2"	"8.9"	"2725.1"	"2637.7"	"3153.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14678"	"Small nuclear ribonucleoprotein-associated proteins B and B' OS=Homo sapiens OX=9606 GN=SNRPB PE=1 SV=2"	"0.000"	""	"25"	"7"	"18"	"7"	"240"	"24.6"	"11.19"	"2113.50"	"36.16"	"6"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6628"	"ENSG00000125835"	"SNRPB"	"hsa:6628; P14678; Q15490; Q6IB35; Q9UIS5"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"509.4"	"300.6"	"542.3"	"359.7"	"367.4"	"388.3"	"892.5"	"1.3"	"4290.2"	"4020.1"	"9072.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q29RF7"	"Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1"	"0.000"	""	"7"	"7"	"13"	"5"	"1337"	"150.7"	"7.91"	"1700.22"	"35.90"	"3"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf20168"	"23244"	"ENSG00000121892"	"PDS5A"	"hsa:23244; Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"6"	"0"	"79.0"	"61.6"	"96.6"	"79.5"	"77.9"	"81.6"	"141.3"	"10.3"	"943.8"	"894.7"	"1845.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06330"	"Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3"	"0.000"	""	"23"	"8"	"15"	"8"	"500"	"55.6"	"7.18"	"2280.91"	"35.80"	"5"	"8"	"cell cycle OR cell proliferation;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09270, Pf09271, Pf20144"	"3516"	"ENSG00000168214"	"RBPJ"	"B4DY22; hsa:3516; Q06330; Q5XKH9; Q6P1N3"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Somitogenesis; Formation of paraxial mesoderm; Pre-NOTCH Transcription and Translation; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; PTF1A related regulatory pathway; Epithelial to mesenchymal transition in colorectal cancer; Osteoblast differentiation and related diseases; Genetic causes of porto-sinusoidal vascular disease; Notch signaling pathway"	"20"	"0"	"41.5"	"36.7"	"55.4"	"55.6"	"46.5"	"36.9"	"98.2"	"4.4"	"1800.2"	"1934.4"	"2760.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05519"	"Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1"	"0.000"	""	"20"	"8"	"12"	"8"	"484"	"53.5"	"10.52"	"1064.86"	"35.65"	"3"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00076"	"9295"	"ENSG00000116754"	"SRSF11"	"hsa:9295; Q05519; Q5T758; Q8IWE6"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"5"	"0"	"112.8"	"80.3"	"123.4"	"99.9"	"114.7"	"88.5"	"152.9"	"8.2"	"2555.8"	"2865.2"	"6205.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06454"	"Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2"	"0.000"	""	"14"	"3"	"16"	"3"	"111"	"12.2"	"3.78"	"3976.94"	"35.62"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03247"	"5757"	"ENSG00000187514"	"PTMA"	"hsa:5757; P06454; Q15249; Q15592"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"736.6"	"521.2"	"603.2"	"567.8"	"552.9"	"634.9"	"813.8"	"0.9"	"1199.7"	"1202.0"	"1497.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ29"	"Putative RNA-binding protein Luc7-like 1 OS=Homo sapiens OX=9606 GN=LUC7L PE=1 SV=1"	"0.000"	""	"20"	"7"	"16"	"3"	"371"	"43.7"	"9.92"	"1797.43"	"35.58"	"4"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"55692"	"ENSG00000007392"	"LUC7L"	"B8ZZ13; hsa:55692; Q96S32; Q9NPH4; Q9NQ29"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"68.7"	"46.9"	"73.7"	"64.7"	"65.8"	"70.6"	"204.9"	"1.3"	"1534.8"	"1535.4"	"3180.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L7X3"	"Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1"	"0.000"	""	"10"	"8"	"17"	"8"	"1001"	"116.0"	"7.65"	"3718.45"	"35.52"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"57551"	"ENSG00000160551"	"TAOK1"	"A2RUT8; B7ZLV6; hsa:57551; Q7L7X3; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Microtubule cytoskeleton regulation; MAPK signaling pathway"	"8"	"0"	"72.0"	"50.9"	"91.6"	"77.1"	"79.6"	"80.6"	"165.4"	"5.1"	"1582.1"	"1577.5"	"2981.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13112"	"Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1"	"0.000"	""	"18"	"8"	"14"	"8"	"559"	"61.5"	"7.50"	"2205.23"	"35.52"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf15512"	"8208"	"ENSG00000159259"	"CHAF1B"	"hsa:8208; Q13112; Q99548"	""	""	"0"	"0"	"207.1"	"162.0"	"230.3"	"217.6"	"198.6"	"198.5"	"369.6"	"10.3"	"3074.5"	"2981.1"	"5872.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34897"	"Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3"	"0.000"	""	"21"	"11"	"22"	"11"	"504"	"56.0"	"8.53"	"4155.91"	"35.25"	"11"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6472"	"ENSG00000182199"	"SHMT2"	"B7Z9F1; E7EQ19; E7EU43; hsa:6472; O00740; P34897; Q8N1A5"	"RHOG GTPase cycle; Metabolism of folate and pterines"	"Glycine metabolism; Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders"	"11"	"0"	"699.8"	"686.2"	"688.6"	"661.1"	"610.6"	"569.7"	"1433.7"	"1.5"	"4047.0"	"4053.9"	"7089.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29692"	"Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5"	"0.000"	""	"35"	"10"	"17"	"8"	"281"	"31.1"	"5.01"	"3882.87"	"35.16"	"8"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00736, Pf10587"	"1936"	"ENSG00000104529; ENSG00000273594"	"EEF1D"	"B4DDU4; D3DWK3; E9PBQ9; hsa:1936; P29692; Q4VBZ6; Q969J1; Q96I38"	"Eukaryotic Translation Elongation"	"Translation factors"	"2"	"0"	"477.1"	"274.3"	"363.6"	"319.3"	"348.5"	"391.2"	"529.3"	"10.3"	"2695.7"	"2618.5"	"5120.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50579"	"Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1"	"0.000"	""	"25"	"9"	"16"	"9"	"478"	"52.9"	"5.82"	"2300.97"	"35.10"	"6"	"9"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00557"	"10988"	"ENSG00000111142"	"METAP2"	"B2RDI8; B4DUX5; G3XA91; hsa:10988; P50579; Q8NB11"	"Inactivation, recovery and regulation of the phototransduction cascade"	""	"1"	"0"	"63.3"	"64.5"	"76.4"	"90.5"	"72.6"	"91.8"	"147.9"	"5.3"	"1676.5"	"1736.7"	"3567.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62995"	"Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1"	"0.000"	""	"31"	"9"	"21"	"8"	"288"	"33.6"	"11.25"	"2789.25"	"35.06"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6434"	"ENSG00000136527"	"TRA2B"	"B4DVK2; D3DNU3; hsa:6434; O15449; P62995; Q15815; Q64283"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"5"	"1"	"880.6"	"762.5"	"727.1"	"744.0"	"634.9"	"679.3"	"1352.0"	"4.4"	"2421.2"	"2559.9"	"3894.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14168"	"MAGUK p55 subfamily member 2 OS=Homo sapiens OX=9606 GN=MPP2 PE=1 SV=3"	"0.000"	""	"22"	"10"	"19"	"9"	"576"	"64.5"	"6.77"	"3380.93"	"34.98"	"9"	"10"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"4355"	"ENSG00000108852"	"MPP2"	"B4DGE9; B4DRJ0; B7Z3G8; E7EV80; E7EV91; E7EX01; hsa:4355; Q14168; Q53ES9; Q5CZB9; Q9BQJ2"	""	""	"0"	"0"	"147.8"	"104.9"	"155.6"	"151.4"	"145.4"	"148.6"	"230.3"	"7.9"	"2741.9"	"2873.6"	"6187.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04908"	"Histone H2A type 1-B/E OS=Homo sapiens OX=9606 GN=H2AC4 PE=1 SV=2"	"0.000"	""	"32"	"3"	"17"	"1"	"130"	"14.1"	"11.05"	"3000.15"	"34.95"	"3"	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3012; 8335"	"ENSG00000277075; ENSG00000278463"	"H2AC4; H2AC8"	"hsa:3012; hsa:8335; P04908; P28001; Q76P63"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Metalloprotease DUBs; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"Proteasome degradation"	"42"	"0"	"17.4"	"22.7"	"28.6"	"23.9"	"20.5"	"28.9"	"148.6"	"0.0"	"306.7"	"594.4"	"302.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBL3"	"Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1"	"0.000"	""	"14"	"7"	"13"	"7"	"628"	"68.7"	"5.69"	"2401.81"	"34.88"	"4"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622"	"9070"	"ENSG00000129691"	"ASH2L"	"A8K7C3; D3DSW9; hsa:9070; O60659; O60660; Q96B62; Q9UBL3"	"Deactivation of the beta-catenin transactivating complex; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"Kleefstra syndrome"	"7"	"0"	"94.7"	"75.2"	"106.0"	"96.1"	"108.1"	"101.8"	"198.1"	"8.5"	"2168.3"	"2208.3"	"5092.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2W2"	"WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1"	"0.000"	""	"11"	"5"	"13"	"5"	"641"	"70.0"	"8.38"	"2304.74"	"34.88"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09429"	"51729"	"ENSG00000084463"	"WBP11"	"hsa:51729; Q96AY8; Q9Y2W2"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"130.1"	"112.6"	"128.0"	"120.0"	"116.5"	"132.6"	"327.1"	"9.6"	"1383.0"	"1554.1"	"2930.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FN4"	"Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3"	"0.000"	""	"18"	"7"	"14"	"6"	"548"	"61.2"	"6.07"	"2377.52"	"34.83"	"6"	"7"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf07002"	"221184"	"ENSG00000140848"	"CPNE2"	"hsa:221184; Q68D19; Q719H8; Q86XP9; Q96FN4"	""	""	"0"	"0"	"38.3"	"24.1"	"50.5"	"39.3"	"41.9"	"37.4"	"71.9"	"1.5"	"1617.8"	"1830.9"	"3693.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ61"	"Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1"	"0.000"	""	"35"	"6"	"13"	"6"	"176"	"18.4"	"9.44"	"1630.56"	"34.79"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	""	"79002"	"ENSG00000123144"	"TRIR"	"hsa:79002; Q9BQ61"	""	""	"0"	"0"	"337.2"	"250.4"	"363.6"	"326.3"	"348.4"	"296.4"	"670.9"	"10.9"	"3640.4"	"3527.1"	"7147.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14776"	"Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2"	"0.000"	""	"10"	"10"	"17"	"9"	"1098"	"123.8"	"8.65"	"3135.55"	"34.66"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00397, Pf01846"	"10915"	"ENSG00000113649"	"TCERG1"	"hsa:10915; O14776; Q2NKN2; Q59EA1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"368.6"	"306.5"	"396.6"	"387.4"	"344.4"	"392.8"	"704.6"	"9.7"	"3726.6"	"3885.5"	"8885.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13151"	"Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1"	"0.000"	""	"21"	"7"	"28"	"5"	"305"	"30.8"	"9.29"	"4603.90"	"34.64"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10949"	"ENSG00000177733"	"HNRNPA0"	"hsa:10949; Q13151; Q6IB18"	""	""	"0"	"0"	"659.8"	"573.8"	"581.7"	"555.4"	"528.5"	"607.5"	"1453.5"	"0.0"	"2764.6"	"2928.8"	"4493.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16104"	"Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2"	"0.000"	""	"33"	"4"	"14"	"2"	"143"	"15.1"	"10.74"	"2302.09"	"34.61"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3014"	"ENSG00000188486"	"H2AX"	"hsa:3014; P16104; Q4ZGJ7; Q6IAS5"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; RMTs methylate histone arginines; Amyloid fiber formation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; Meiotic synapsis; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; G2/M DNA damage checkpoint; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Proteasome degradation; ATM signaling in development and disease ; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DNA repair pathways, full network; 5q35 copy number variation; DNA damage response"	"46"	"3"	"337.9"	"267.6"	"368.4"	"303.5"	"294.6"	"329.2"	"1110.5"	"4.0"	"2293.0"	"2392.7"	"4112.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15880"	"40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2"	"0.000"	""	"29"	"9"	"19"	"9"	"293"	"31.3"	"10.24"	"3533.35"	"34.61"	"8"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00333, Pf03719"	"6187"	"ENSG00000140988"	"RPS2"	"B2R5G0; D3DU82; hsa:6187; P15880; Q3MIB1"	"Regulation of expression of SLITs and ROBOs; RMTs methylate histone arginines; Protein methylation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"22"	"0"	"333.9"	"317.5"	"307.7"	"277.4"	"286.3"	"279.9"	"957.0"	"11.2"	"6099.9"	"6757.7"	"11806.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMR2"	"ATP-dependent RNA helicase DDX19B OS=Homo sapiens OX=9606 GN=DDX19B PE=1 SV=1"	"0.000"	""	"21"	"7"	"13"	"1"	"479"	"53.9"	"6.30"	"2201.54"	"34.55"	"4"	"7"	"other metabolic processes;transport"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11269"	"ENSG00000157349"	"DDX19B"	"B3KNE9; B4DXS6; E7EMK4; hsa:11269; Q6FIB7; Q6IAE0; Q96KE7; Q9H0U0; Q9UMR2"	""	""	"0"	"0"	"20.7"	"14.9"	"29.8"	"27.9"	"20.8"	"23.5"	"75.0"	"0.0"	"326.1"	"234.3"	"633.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI27"	"THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2"	"0.000"	""	"8"	"12"	"26"	"12"	"1593"	"182.7"	"8.44"	"4782.36"	"34.55"	"12"	"10"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf11262, Pf11732, Pf16134"	"57187"	"ENSG00000125676"	"THOC2"	"A6NM50; hsa:57187; Q5JZ12; Q6IN92; Q8NI27; Q9H8I6"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"653.1"	"507.6"	"672.8"	"654.3"	"564.4"	"612.2"	"1266.9"	"10.8"	"6145.5"	"5916.0"	"13236.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVA2"	"Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3"	"0.000"	""	"20"	"8"	"19"	"5"	"429"	"49.4"	"6.81"	"3572.13"	"34.51"	"8"	"8"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55752"	"ENSG00000138758"	"SEPTIN11"	"B7Z7Z6; E9KL32; hsa:55752; Q4W5G1; Q7L4N1; Q96SP1; Q9NVA2; Q9UFY9"	""	"22q11.2 copy number variation syndrome"	"1"	"3"	"185.9"	"138.8"	"189.4"	"177.6"	"194.1"	"191.3"	"363.6"	"7.5"	"4237.6"	"4109.5"	"7665.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43246"	"DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1"	"0.000"	""	"12"	"8"	"14"	"8"	"934"	"104.7"	"5.77"	"1687.00"	"34.30"	"4"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05190, Pf05192"	"4436"	"ENSG00000095002"	"MSH2"	"B4E2Z2; hsa:4436; O75488; P43246"	"TP53 Regulates Transcription of DNA Repair Genes; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"RAC1/PAK1/p38/MMP2 pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ciliary landscape; DNA repair pathways, full network; p53 transcriptional gene network; DNA mismatch repair"	"12"	"0"	"126.5"	"98.5"	"158.1"	"135.0"	"122.7"	"128.6"	"263.0"	"4.0"	"2112.2"	"2144.8"	"5176.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZS1"	"DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3"	"0.000"	""	"25"	"10"	"17"	"10"	"419"	"47.2"	"8.94"	"2694.80"	"34.16"	"7"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06870"	"64425"	"ENSG00000137054"	"POLR1E"	"hsa:64425; Q5VZT3; Q8NBA9; Q96L20; Q9GZS1"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"8"	"0"	"147.5"	"116.0"	"176.0"	"149.2"	"159.9"	"152.4"	"406.4"	"15.5"	"4768.9"	"4524.5"	"7935.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42167"	"Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"0.000"	""	"19"	"8"	"14"	"2"	"454"	"50.6"	"9.38"	"3236.27"	"34.10"	"7"	"7"	""	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198"	"7112"	"ENSG00000120802"	"TMPO"	"A2T926; hsa:7112; P42167; Q14861"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"12"	"0"	"62.2"	"59.9"	"55.7"	"52.5"	"52.4"	"53.2"	"111.4"	"0.0"	"498.9"	"509.0"	"917.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07021"	"Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1"	"0.000"	""	"27"	"5"	"14"	"5"	"282"	"31.3"	"4.84"	"2502.93"	"34.06"	"4"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;nucleic acid binding activity;other molecular function"	"Pf02330"	"708"	"ENSG00000108561"	"C1QBP"	"hsa:708; Q07021; Q2HXR8; Q9NNY8"	"RHOC GTPase cycle; RHOA GTPase cycle; Intrinsic Pathway of Fibrin Clot Formation; Apoptotic factor-mediated response; Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"	"Complement system; Mesodermal commitment pathway; Ebola virus infection in host"	"8"	"0"	"516.3"	"387.6"	"545.3"	"499.0"	"423.2"	"471.4"	"1394.4"	"2.0"	"2615.1"	"2636.3"	"4530.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0D6"	"5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1"	"0.000"	""	"16"	"11"	"20"	"11"	"950"	"108.5"	"7.47"	"4707.59"	"33.98"	"10"	"8"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846"	"22803"	"ENSG00000088930"	"XRN2"	"hsa:22803; Q3L8N4; Q6KGZ9; Q9BQL1; Q9H0D6; Q9NTW0; Q9NXS6; Q9UL53"	"Major pathway of rRNA processing in the nucleolus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"mRNA processing"	"3"	"0"	"404.9"	"320.9"	"422.3"	"373.8"	"386.6"	"378.8"	"677.3"	"18.3"	"2894.3"	"2762.1"	"5352.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55081"	"Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2"	"0.000"	""	"16"	"8"	"17"	"8"	"439"	"51.9"	"4.98"	"3470.54"	"33.83"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"extracellular matrix;cytoskeleton;nucleus"	""	"Pf06991"	"4236"	"ENSG00000140259"	"MFAP1"	"hsa:4236; P55081; Q86TG6"	"mRNA Splicing - Major Pathway"	"Canonical and non-canonical Notch signaling; Ciliary landscape"	"3"	"0"	"500.9"	"386.3"	"474.3"	"473.7"	"388.3"	"470.1"	"884.4"	"10.2"	"3285.0"	"3395.2"	"7194.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05388"	"60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1"	"0.000"	""	"27"	"8"	"16"	"8"	"317"	"34.3"	"5.97"	"3375.78"	"33.80"	"8"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00428, Pf00466, Pf17777"	"6175"	"ENSG00000089157"	"RPLP0"	"hsa:6175; P05388; Q3B7A4; Q9BVK4"	"Regulation of expression of SLITs and ROBOs; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"15"	"0"	"92.2"	"70.9"	"125.0"	"95.3"	"113.1"	"94.5"	"438.7"	"1.6"	"2642.0"	"2732.7"	"5432.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DP25"	"Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1"	"0.000"	""	"24"	"6"	"18"	"6"	"149"	"16.8"	"4.22"	"3694.37"	"33.69"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf13499"	"801; 805; 808"	"ENSG00000160014"	"CALM3"	"hsa:801; hsa:805; hsa:808; P02593; P0DP25; P62158; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3"	""	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; Ras signaling; Melanoma; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; Glycogen synthesis and degradation; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; G13 signaling pathway; Calcium regulation in cardiac cells"	"17"	"0"	"321.4"	"233.8"	"461.1"	"354.9"	"371.2"	"420.4"	"1217.4"	"22.3"	"6418.1"	"6195.4"	"9542.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YS7"	"C2 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=C2CD5 PE=1 SV=1"	"0.000"	""	"10"	"9"	"15"	"9"	"1000"	"110.4"	"5.69"	"2021.52"	"33.68"	"6"	"9"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00168"	"9847"	"ENSG00000111731"	"C2CD5"	"B4DJ03; B4DRN7; B7ZLL0; F5H2A1; F5H5R1; hsa:9847; O60280; Q17RY7; Q7Z619; Q86SU3; Q86YS7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	""	"1"	"0"	"108.4"	"77.2"	"121.3"	"107.5"	"118.7"	"155.4"	"352.9"	"6.5"	"4857.0"	"4909.6"	"7662.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92747"	"Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens OX=9606 GN=ARPC1A PE=2 SV=2"	"0.000"	""	"24"	"6"	"14"	"5"	"370"	"41.5"	"8.18"	"1881.71"	"33.60"	"4"	"6"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"10552"	"ENSG00000241685"	"ARPC1A"	"A4D276; B4DLQ7; D6W5S1; hsa:10552; Q7Z5U8; Q86WU5; Q8IXQ0; Q92747"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"2"	"119.9"	"82.7"	"119.4"	"122.6"	"149.4"	"101.2"	"214.1"	"8.4"	"2938.1"	"3076.0"	"7023.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q52LJ0"	"Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2"	"0.000"	""	"21"	"7"	"15"	"5"	"433"	"45.5"	"8.69"	"2643.94"	"33.50"	"6"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"283742"	"ENSG00000171262"	"FAM98B"	"A8MUW5; hsa:283742; Q52LJ0; Q8N935"	"tRNA processing in the nucleus"	""	"1"	"2"	"245.7"	"199.3"	"261.1"	"219.4"	"218.0"	"198.0"	"571.6"	"7.8"	"2183.7"	"2135.5"	"4513.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62826"	"GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3"	"0.000"	""	"25"	"6"	"13"	"6"	"216"	"24.4"	"7.49"	"1710.29"	"33.41"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5901"	"ENSG00000132341"	"RAN"	"A8K3Z8; hsa:5901; P17080; P28746; P28747; P62826; Q6IPB2; Q86V08; Q8NI90; Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9"	"Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Nuclear import of Rev protein; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; Regulation of cholesterol biosynthesis by SREBP (SREBF); MicroRNA (miRNA) biogenesis; Postmitotic nuclear pore complex (NPC) reformation"	"Androgen receptor signaling pathway; miRNA biogenesis; 22q11.2 copy number variation syndrome"	"11"	"0"	"379.6"	"441.8"	"269.6"	"288.2"	"320.3"	"286.6"	"536.6"	"7.7"	"2664.1"	"2930.9"	"8035.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95232"	"Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2"	"0.000"	""	"24"	"9"	"15"	"9"	"432"	"51.4"	"9.79"	"1624.39"	"33.35"	"5"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf03194"	"51747"	"ENSG00000108848"	"LUC7L3"	"B3KN54; D3DTY1; hsa:51747; O95232; Q6PHR9; Q9NUY0; Q9P2S7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"431.6"	"257.6"	"392.2"	"381.7"	"330.4"	"336.4"	"678.2"	"3.9"	"5167.9"	"4913.1"	"11954.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0VDF9"	"Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1"	"0.000"	""	"13"	"6"	"14"	"6"	"509"	"54.8"	"5.59"	"2589.66"	"33.31"	"6"	"6"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00012"	"51182"	"ENSG00000187522"	"HSPA14"	"A8K8F8; B0YIY9; hsa:51182; Q0VDF9; Q9P0X2; Q9UI07"	"Regulation of HSF1-mediated heat shock response"	"Parkin-ubiquitin proteasomal system pathway"	"2"	"0"	"68.6"	"50.3"	"96.9"	"80.5"	"101.4"	"82.1"	"131.2"	"8.4"	"1749.2"	"1649.9"	"4081.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35612"	"Beta-adducin OS=Homo sapiens OX=9606 GN=ADD2 PE=1 SV=3"	"0.000"	""	"17"	"12"	"18"	"9"	"726"	"80.8"	"5.92"	"2610.07"	"33.18"	"7"	"11"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"119"	"ENSG00000075340"	"ADD2"	"A8K4P2; B4DM17; D6W5G7; D6W5G8; hsa:119; P35612; Q13482; Q16412; Q59G82; Q5U5P4; Q6P0P2; Q6PGQ4; Q7Z688; Q7Z689; Q7Z690; Q7Z691"	"Miscellaneous transport and binding events"	""	"1"	"0"	"64.9"	"39.3"	"71.9"	"65.2"	"70.2"	"69.7"	"142.9"	"22.4"	"1808.9"	"1773.3"	"3620.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49006"	"MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2"	"0.000"	""	"54"	"6"	"12"	"6"	"195"	"19.5"	"4.67"	"2064.09"	"33.18"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"65108"	"ENSG00000175130"	"MARCKSL1"	"D3DPQ0; hsa:65108; P49006; Q5TEE6; Q6NXS5"	""	""	"0"	"0"	"23.9"	"16.8"	"33.0"	"28.5"	"27.9"	"22.3"	"47.4"	"7.9"	"1971.6"	"2007.0"	"3933.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15717"	"ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2"	"0.000"	""	"25"	"7"	"18"	"7"	"326"	"36.1"	"9.17"	"3101.19"	"33.17"	"7"	"7"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1994"	"ENSG00000066044"	"ELAVL1"	"B4DVB8; hsa:1994; Q15717; Q53XN6; Q9BTT1"	"HuR (ELAVL1) binds and stabilizes mRNA"	"AMP-activated protein kinase signaling; Endoderm differentiation; Pre-implantation embryo; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Gastrin signaling pathway; IL-18 signaling pathway; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; 1p36 copy number variation syndrome"	"10"	"0"	"475.1"	"406.6"	"495.7"	"441.2"	"483.5"	"386.1"	"810.8"	"2.3"	"3932.9"	"3821.3"	"7765.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62269"	"40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3"	"0.000"	""	"44"	"10"	"20"	"10"	"152"	"17.7"	"10.99"	"3705.86"	"33.13"	"9"	"8"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00416"	"6222"	"ENSG00000096150; ENSG00000223367; ENSG00000226225; ENSG00000231500; ENSG00000235650"	"RPS18"	"hsa:6222; P25232; P62269; Q5SUJ3; Q6IPF8"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"547.7"	"448.7"	"558.0"	"508.5"	"494.1"	"524.1"	"1594.0"	"5.7"	"5051.7"	"5078.6"	"9867.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14644"	"Ras GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=RASA3 PE=1 SV=3"	"0.000"	""	"11"	"8"	"17"	"8"	"834"	"95.6"	"7.15"	"2534.08"	"32.94"	"7"	"8"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"transporter activity;enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"22821"	"ENSG00000185989; ENSG00000280477"	"RASA3"	"A6NL15; F8W6X8; hsa:22821; Q14644; Q8IUY2"	"Regulation of RAS by GAPs"	"MAPK cascade; Ras signaling; IL-18 signaling pathway"	"4"	"0"	"103.2"	"76.1"	"133.7"	"98.8"	"131.1"	"131.1"	"268.7"	"3.4"	"2433.9"	"2382.7"	"3735.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A65"	"Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1"	"0.000"	""	"10"	"9"	"18"	"9"	"974"	"110.4"	"6.49"	"3608.14"	"32.84"	"9"	"9"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf04048"	"60412"	"ENSG00000131558"	"EXOC4"	"E9PED2; hsa:60412; Q541U8; Q96A65; Q9C0G4; Q9H9K0; Q9P102"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"118.4"	"85.3"	"129.5"	"129.4"	"149.1"	"179.9"	"412.9"	"10.0"	"3839.1"	"3795.9"	"5937.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60885"	"Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2"	"0.000"	""	"7"	"9"	"15"	"9"	"1362"	"152.1"	"9.19"	"2647.81"	"32.77"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf17035, Pf17105"	"23476"	"ENSG00000141867"	"BRD4"	"hsa:23476; O60433; O60885; Q4G0X8; Q86YS8; Q96PD3"	"Potential therapeutics for SARS"	"VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"3"	"0"	"183.6"	"164.1"	"189.1"	"199.4"	"195.6"	"199.9"	"435.4"	"8.3"	"2040.3"	"1885.8"	"4087.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27348"	"14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1"	"0.000"	""	"32"	"7"	"19"	"4"	"245"	"27.7"	"4.78"	"3806.25"	"32.73"	"7"	"7"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00244"	"10971"	"ENSG00000134308"	"YWHAQ"	"D6W4Z5; hsa:10971; P27348; Q567U5; Q5TZU8; Q9UP48"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Leukocyte-intrinsic Hippo pathway functions; Hepatitis B infection; Opioid receptor pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"20"	"0"	"116.6"	"125.9"	"110.2"	"117.9"	"124.3"	"94.6"	"218.0"	"3.7"	"1895.3"	"1791.6"	"3528.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFW8"	"N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2"	"0.000"	""	"23"	"6"	"12"	"6"	"434"	"48.3"	"7.93"	"2282.36"	"32.69"	"4"	"6"	"other metabolic processes"	"nucleus"	"other molecular function"	"Pf02348"	"55907"	"ENSG00000111726"	"CMAS"	"hsa:55907; Q8NFW8; Q96AX5; Q9NQZ0"	"Sialic acid metabolism"	""	"1"	"0"	"65.0"	"52.0"	"88.4"	"75.8"	"68.9"	"52.7"	"208.9"	"9.6"	"1561.1"	"1551.8"	"3219.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y606"	"tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3"	"0.000"	""	"28"	"9"	"15"	"9"	"427"	"47.4"	"8.41"	"2043.46"	"32.61"	"6"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01416"	"80324"	"ENSG00000177192"	"PUS1"	"A8K877; B3KQC1; hsa:80324; Q8WYT2; Q9BU44; Q9Y606"	""	""	"0"	"0"	"95.5"	"66.2"	"115.4"	"93.6"	"112.9"	"90.6"	"171.2"	"6.6"	"1550.6"	"1595.8"	"3780.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62318"	"Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1"	"0.000"	""	"56"	"7"	"13"	"7"	"126"	"13.9"	"10.32"	"2170.45"	"32.61"	"4"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6634"	"ENSG00000100028"	"SNRPD3"	"B4DJP7; B5BU13; hsa:6634; P43331; P62318"	"mRNA Splicing - Major Pathway; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"740.2"	"507.2"	"797.7"	"645.4"	"670.6"	"580.9"	"1318.1"	"3.0"	"3838.8"	"3802.5"	"7054.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UN15"	"Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1"	"0.000"	""	"21"	"8"	"17"	"8"	"594"	"66.5"	"5.59"	"3988.28"	"32.56"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf05182"	"81608"	"ENSG00000145216"	"FIP1L1"	"B4DIR3; G3XAD6; hsa:81608; Q0VGE0; Q499Y4; Q49AU3; Q6UN15; Q7Z608; Q8WVN3; Q96F80; Q9H077"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	""	"6"	"0"	"763.1"	"571.0"	"536.5"	"618.8"	"537.3"	"583.1"	"1029.2"	"4.7"	"3309.7"	"3385.3"	"5838.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00148"	"ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2"	"0.000"	""	"19"	"8"	"17"	"2"	"427"	"49.1"	"5.68"	"2951.05"	"32.52"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"10212"	"ENSG00000123136"	"DDX39A"	"B1Q2N1; hsa:10212; O00148; Q8N5M0; Q9BVP6; Q9H5W0"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"44.2"	"29.1"	"82.3"	"42.6"	"61.3"	"44.9"	"97.4"	"3.7"	"378.7"	"375.6"	"947.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52292"	"Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1"	"0.000"	""	"22"	"9"	"15"	"9"	"529"	"57.8"	"5.40"	"3100.23"	"32.44"	"8"	"7"	"DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3838"	"ENSG00000182481"	"KPNA2"	"B9EJD6; hsa:3838; P52292; Q53YE3; Q6NVW7; Q9BRU5"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Estrogen-dependent gene expression; SARS-CoV-1 activates/modulates innate immune responses; Sensing of DNA Double Strand Breaks; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	""	"8"	"0"	"457.6"	"360.9"	"512.2"	"438.7"	"384.2"	"408.6"	"853.0"	"5.3"	"4539.4"	"4689.2"	"8694.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07666"	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1"	"0.000"	""	"19"	"9"	"19"	"9"	"443"	"48.2"	"8.66"	"3334.75"	"32.29"	"8"	"8"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16274, Pf16568"	"10657"	"ENSG00000121774"	"KHDRBS1"	"D3DPP3; hsa:10657; Q07666; Q6PJX7; Q8NB97; Q99760"	"PTK6 Regulates Proteins Involved in RNA Processing"	"Leptin signaling pathway; Primary ovarian insufficiency"	"3"	"0"	"1055.8"	"984.9"	"1230.8"	"981.3"	"954.5"	"1031.3"	"2490.9"	"0.0"	"5318.3"	"5066.5"	"8206.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55084"	"Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3"	"0.000"	""	"19"	"9"	"17"	"9"	"474"	"51.3"	"9.41"	"4067.40"	"32.13"	"9"	"8"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"nucleic acid binding activity;other molecular function"	"Pf00108, Pf02803"	"3032"	"ENSG00000138029"	"HADHB"	"B2RB16; B4E2W0; hsa:3032; O14969; P55084; Q53TA6; Q96C77; Q9H3F5; Q9T2V8"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"Fatty acid beta-oxidation; Valproic acid pathway; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"12"	"0"	"428.4"	"341.5"	"433.1"	"410.5"	"409.4"	"424.1"	"724.6"	"5.8"	"3258.2"	"3285.8"	"6880.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06744"	"Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4"	"0.000"	""	"18"	"7"	"12"	"7"	"558"	"63.1"	"8.32"	"1596.99"	"31.98"	"4"	"7"	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00342"	"2821"	"ENSG00000105220"	"GPI"	"B4DG39; hsa:2821; P06744; Q9BRD3; Q9BSK5; Q9UHE6"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis; TP53 Regulates Metabolic Genes"	"Cori cycle; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; N-glycan biosynthesis; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"13"	"0"	"95.2"	"70.7"	"105.6"	"99.1"	"97.0"	"112.7"	"236.1"	"0.9"	"2163.5"	"2421.9"	"6982.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48444"	"Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1"	"0.000"	""	"17"	"8"	"15"	"8"	"511"	"57.2"	"6.21"	"2834.53"	"31.96"	"7"	"8"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf00928, Pf01217"	"372"	"ENSG00000095139"	"ARCN1"	"B4E1X2; E9PEU4; hsa:372; P48444; Q52M80"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"miR-517 relationship with ARCN1 and USP1"	"3"	"0"	"136.9"	"87.8"	"158.9"	"129.9"	"125.6"	"127.0"	"210.8"	"13.9"	"2236.9"	"2137.7"	"4809.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSD9"	"Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3"	"0.000"	""	"16"	"8"	"17"	"8"	"589"	"66.1"	"6.84"	"2740.75"	"31.93"	"7"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03483, Pf03484, Pf17759, Pf18262"	"10056"	"ENSG00000116120"	"FARSB"	"B4DFM0; hsa:10056; O95708; Q4ZFX1; Q57ZJ5; Q9NSD9; Q9NZZ6"	"Cytosolic tRNA aminoacylation"	"VEGFA-VEGFR2 signaling; Amino acid metabolism"	"3"	"0"	"115.4"	"95.0"	"171.0"	"127.2"	"149.5"	"198.4"	"350.4"	"11.4"	"2470.7"	"2743.8"	"4531.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18583"	"Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4"	"0.000"	""	"4"	"8"	"16"	"8"	"2426"	"263.7"	"5.64"	"2845.68"	"31.90"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf14709, Pf17069"	"6651"	"ENSG00000159140"	"SON"	"D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2; hsa:6651; O14487; O95981; P18583; Q14120; Q6PKE0; Q9H7B1; Q9P070; Q9P072; Q9UKP9; Q9UPY0"	""	""	"0"	"0"	"293.2"	"218.2"	"287.8"	"287.8"	"235.2"	"267.0"	"590.6"	"3.5"	"2719.3"	"2855.3"	"6126.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43663"	"Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2"	"0.000"	""	"14"	"7"	"15"	"6"	"620"	"71.6"	"6.68"	"2978.56"	"31.86"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03999"	"9055"	"ENSG00000198901"	"PRC1"	"A6NC44; B4DLR1; H9KV59; hsa:9055; O43663; Q9BSB6"	"RHO GTPases activate CIT"	""	"1"	"0"	"61.3"	"52.0"	"55.2"	"53.5"	"63.9"	"54.7"	"139.3"	"8.1"	"1835.3"	"1850.0"	"4141.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49589"	"Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3"	"0.000"	""	"14"	"8"	"12"	"8"	"748"	"85.4"	"6.76"	"1834.65"	"31.73"	"4"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01406"	"833"	"ENSG00000110619; ENSG00000278191"	"CARS1"	"hsa:833; P49589; Q53XI8; Q5HYE4; Q9HD24; Q9HD25"	"Cytosolic tRNA aminoacylation; Signaling by ALK fusions and activated point mutants"	""	"2"	"0"	"46.1"	"45.1"	"65.2"	"46.6"	"53.3"	"59.9"	"115.3"	"6.1"	"2309.6"	"2348.8"	"6336.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36873"	"Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1"	"0.000"	""	"25"	"7"	"13"	"2"	"323"	"37.0"	"6.54"	"2529.44"	"31.72"	"6"	"7"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5501"	"ENSG00000186298"	"PPP1CC"	"hsa:5501; P36873"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Triglyceride catabolism; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; Downregulation of TGF-beta receptor signaling"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; Neuroinflammation and glutamatergic signaling"	"16"	"0"	"116.3"	"79.9"	"99.1"	"103.5"	"113.0"	"95.8"	"211.7"	"0.0"	"729.3"	"675.9"	"1398.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VUJ6"	"Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2"	"0.000"	""	"17"	"7"	"11"	"7"	"765"	"84.5"	"6.55"	"1790.53"	"31.71"	"4"	"7"	""	""	""	"Pf00307, Pf13855"	"57631"	"ENSG00000130224"	"LRCH2"	"F5H2T1; hsa:57631; Q08AD5; Q5VUJ6; Q9HA88; Q9P233"	""	""	"0"	"0"	"87.9"	"58.6"	"94.0"	"92.2"	"92.1"	"87.2"	"144.6"	"2.5"	"895.8"	"806.2"	"1860.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13263"	"Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5"	"0.000"	""	"9"	"6"	"12"	"6"	"835"	"88.5"	"5.77"	"2758.00"	"31.70"	"4"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00628, Pf00643, Pf14634"	"10155"	"ENSG00000130726"	"TRIM28"	"hsa:10155; O00677; Q13263; Q7Z632; Q93040; Q96IM1"	"HCMV Early Events; SUMOylation of transcription cofactors; Generic Transcription Pathway"	"Corticotropin-releasing hormone signaling pathway; Mesodermal commitment pathway; ATM signaling in development and disease"	"6"	"0"	"141.4"	"108.4"	"152.0"	"161.4"	"139.1"	"131.4"	"214.6"	"4.4"	"1575.0"	"1594.2"	"4853.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00367"	"Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2"	"0.000"	""	"19"	"10"	"18"	"10"	"558"	"61.4"	"7.80"	"2831.50"	"31.66"	"9"	"9"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00208, Pf02812"	"2746"	"ENSG00000148672"	"GLUD1"	"B3KV55; B4DGN5; hsa:2746; P00367; Q5TBU3"	"Transcriptional activation of mitochondrial biogenesis; Glutamate and glutamine metabolism"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Metabolic reprogramming in colon cancer; 22q11.2 copy number variation syndrome; Amino acid metabolism pathway excerpt: histidine catabolism extension; 10q22q23 copy number variation"	"8"	"0"	"372.9"	"330.9"	"391.8"	"349.3"	"327.3"	"324.3"	"574.9"	"0.6"	"4125.3"	"4688.5"	"9246.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15446"	"DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1"	"0.000"	""	"22"	"6"	"14"	"6"	"510"	"55.0"	"8.51"	"2113.57"	"31.49"	"4"	"6"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf08208"	"10849"	"ENSG00000117877"	"POLR1G"	"hsa:10849; O15446; Q32N11; Q7Z5U2; Q9UPF6"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"2q13 copy number variation syndrome"	"6"	"0"	"44.1"	"31.0"	"51.1"	"39.4"	"49.0"	"57.3"	"98.7"	"4.2"	"1062.6"	"996.7"	"1730.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHR4"	"Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2"	"0.000"	""	"16"	"7"	"16"	"7"	"511"	"56.8"	"8.68"	"3238.61"	"31.44"	"7"	"7"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf08397, Pf14604"	"55971"	"ENSG00000006453"	"BAIAP2L1"	"A4D268; hsa:55971; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9UHR4; Q9Y2M8"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOF GTPase cycle"	""	"4"	"0"	"117.9"	"111.0"	"168.5"	"129.5"	"132.4"	"148.8"	"326.6"	"16.3"	"3342.2"	"3064.1"	"5405.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46782"	"40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4"	"0.000"	""	"33"	"7"	"17"	"7"	"204"	"22.9"	"9.72"	"2987.48"	"31.37"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"6193"	"ENSG00000083845"	"RPS5"	"B2R4T2; hsa:6193; P46782; Q96BN0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"133.8"	"115.3"	"141.4"	"133.7"	"129.3"	"113.2"	"417.6"	"4.4"	"2557.4"	"3114.1"	"5529.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63279"	"SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1"	"0.000"	""	"40"	"6"	"14"	"6"	"158"	"18.0"	"8.66"	"2983.90"	"31.31"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7329"	"ENSG00000103275"	"UBE2I"	"D3DU69; hsa:7329; P50550; P63279; Q15698; Q59GX1; Q86VB3"	"SUMOylation of RNA binding proteins; Formation of Incision Complex in GG-NER; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; Meiotic synapsis; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Processing of DNA double-strand break ends; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"Androgen receptor signaling pathway; TAR syndrome"	"25"	"0"	"383.2"	"323.3"	"378.0"	"353.8"	"395.0"	"282.7"	"798.6"	"10.5"	"4086.9"	"3831.6"	"8845.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50395"	"Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2"	"0.000"	""	"18"	"6"	"9"	"6"	"445"	"50.6"	"6.47"	"1203.93"	"31.07"	"2"	"6"	"transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2665"	"ENSG00000057608"	"GDI2"	"hsa:2665; O43928; P50395; Q5SX88; Q9UQM6"	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs"	""	"2"	"0"	"20.6"	"13.5"	"31.2"	"21.6"	"30.9"	"20.5"	"57.4"	"10.7"	"630.3"	"581.5"	"2578.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60256"	"Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1"	"0.000"	""	"22"	"8"	"16"	"8"	"369"	"40.9"	"7.44"	"2430.61"	"31.06"	"6"	"8"	"other metabolic processes;developmental processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5636"	"ENSG00000141127"	"PRPSAP2"	"B4E1M8; B4E329; B7ZKZ1; E7EMY2; hsa:5636; O60256; Q6IAS2"	""	""	"0"	"0"	"129.1"	"107.9"	"136.6"	"143.6"	"151.4"	"193.3"	"290.6"	"13.6"	"2474.4"	"2552.1"	"5590.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01105"	"Protein SET OS=Homo sapiens OX=9606 GN=SET PE=1 SV=3"	"0.000"	""	"27"	"6"	"13"	"6"	"290"	"33.5"	"4.32"	"2533.96"	"31.02"	"5"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00956"	"6418"	"ENSG00000119335"	"SET"	"A5A5H4; A6NGV1; B4DUE2; hsa:6418; Q01105; Q15541; Q5VXV1; Q5VXV2; Q6FHZ5"	"HuR (ELAVL1) binds and stabilizes mRNA; Condensation of Prophase Chromosomes"	"Histone modifications; VEGFA-VEGFR2 signaling"	"4"	"0"	"154.0"	"212.7"	"167.1"	"159.6"	"189.3"	"202.6"	"716.8"	"7.2"	"2932.7"	"2908.3"	"4071.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62424"	"60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2"	"0.000"	""	"38"	"10"	"18"	"10"	"266"	"30.0"	"10.61"	"3072.73"	"30.85"	"9"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6130"	"ENSG00000148303; ENSG00000280858"	"RPL7A"	"hsa:6130; P11518; P62424; Q5T8U4"	"Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"326.9"	"257.0"	"322.6"	"294.3"	"274.6"	"302.3"	"1189.1"	"9.8"	"3031.5"	"2931.3"	"5392.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14444"	"Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2"	"0.000"	""	"14"	"9"	"18"	"9"	"709"	"78.3"	"5.25"	"3070.13"	"30.83"	"8"	"8"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12287, Pf18293"	"4076"	"ENSG00000135387"	"CAPRIN1"	"A6NMY7; D3DR06; hsa:4076; Q14444; Q15074; Q6IMN4; Q6IMN7; Q9BV09"	""	""	"0"	"0"	"216.1"	"175.9"	"169.7"	"186.3"	"165.5"	"196.7"	"635.0"	"20.8"	"3149.5"	"3062.0"	"5815.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01484"	"Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4"	"0.000"	""	"2"	"9"	"17"	"5"	"3957"	"433.4"	"5.14"	"3012.07"	"30.82"	"8"	"9"	"cell-cell signaling;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00023, Pf00531, Pf00791, Pf12796, Pf17809"	"287"	"ENSG00000145362"	"ANK2"	"hsa:287; Q01484; Q01485; Q08AC7; Q08AC8; Q7Z3L5"	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	""	"2"	"1"	"57.9"	"42.6"	"77.1"	"66.3"	"59.7"	"59.3"	"111.1"	"4.9"	"820.0"	"803.0"	"1734.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25398"	"40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3"	"0.000"	""	"46"	"6"	"11"	"6"	"132"	"14.5"	"7.21"	"1378.11"	"30.66"	"3"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6206"	"ENSG00000112306"	"RPS12"	"hsa:6206; P25398; Q76M58"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"239.2"	"208.5"	"240.1"	"218.8"	"213.8"	"159.8"	"706.7"	"7.9"	"3282.1"	"3488.4"	"6345.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49915"	"GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1"	"0.000"	""	"15"	"6"	"10"	"6"	"693"	"76.7"	"6.87"	"1561.78"	"30.54"	"3"	"6"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00117, Pf00958, Pf02540"	"8833"	"ENSG00000163655"	"GMPS"	"A8K639; B4DXV7; F8W720; hsa:8833; P49915"	"Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	""	"2"	"0"	"22.3"	"14.6"	"29.4"	"20.2"	"24.8"	"27.5"	"53.5"	"6.7"	"1007.8"	"971.3"	"3271.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15160"	"DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1"	"0.000"	""	"29"	"9"	"16"	"9"	"346"	"39.2"	"5.50"	"2352.29"	"30.52"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"9533"	"ENSG00000171453"	"POLR1C"	"hsa:9533; O15160; O75395; Q5JTE3"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"15"	"0"	"65.0"	"48.3"	"85.6"	"75.0"	"91.9"	"74.7"	"152.0"	"2.6"	"2807.3"	"2625.7"	"4794.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43175"	"D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4"	"0.000"	""	"17"	"7"	"15"	"7"	"533"	"56.6"	"6.71"	"2615.57"	"30.34"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00389, Pf02826, Pf19304"	"26227"	"ENSG00000092621"	"PHGDH"	"B2RD08; hsa:26227; O43175; Q5SZU3; Q9BQ01"	"Serine biosynthesis"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"5"	"0"	"170.3"	"109.8"	"191.5"	"164.8"	"205.5"	"158.4"	"247.3"	"0.9"	"1929.5"	"2082.3"	"4614.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41223"	"Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2"	"0.000"	""	"52"	"9"	"14"	"9"	"144"	"17.0"	"8.82"	"2252.02"	"30.24"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01125"	"8896"	"ENSG00000106245"	"BUD31"	"A4D274; B7Z4S9; D6W5S6; hsa:8896; P41223; Q6IB53; Q9UDV1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"186.5"	"140.3"	"209.8"	"215.8"	"200.6"	"177.8"	"388.8"	"17.2"	"3215.8"	"3068.7"	"6909.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39023"	"60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2"	"0.000"	""	"25"	"11"	"18"	"11"	"403"	"46.1"	"10.18"	"2695.26"	"30.21"	"9"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00297"	"6122"	"ENSG00000100316"	"RPL3"	"B2RDV9; hsa:6122; P39023; Q15548; Q5I0G0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"411.6"	"323.5"	"452.6"	"385.7"	"401.2"	"417.5"	"1633.9"	"1.6"	"6145.8"	"6096.5"	"10976.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13283"	"Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1"	"0.000"	""	"24"	"8"	"15"	"8"	"466"	"52.1"	"5.52"	"2433.58"	"30.16"	"7"	"8"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"10146"	"ENSG00000145907"	"G3BP1"	"hsa:10146; Q13283; Q5HYE9"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"1"	"0"	"145.3"	"124.3"	"171.1"	"149.0"	"152.7"	"153.6"	"400.8"	"12.6"	"1959.3"	"1898.4"	"3332.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46783"	"40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1"	"0.000"	""	"43"	"8"	"27"	"6"	"165"	"18.9"	"10.15"	"5596.74"	"30.05"	"8"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03501"	"6204"	"ENSG00000124614"	"RPS10"	"B2R4E3; hsa:6204; P46783; Q5TZC0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"547.2"	"449.7"	"506.3"	"509.6"	"491.0"	"525.6"	"1874.7"	"4.1"	"5048.9"	"5550.4"	"10276.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52209"	"6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3"	"0.000"	""	"23"	"8"	"11"	"8"	"483"	"53.1"	"7.23"	"1247.43"	"30.05"	"3"	"8"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00393, Pf03446"	"5226"	"ENSG00000142657"	"PGD"	"A8K2Y9; B4DQJ8; hsa:5226; P52209; Q9BWD8"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"Pentose phosphate metabolism; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer"	"7"	"0"	"163.4"	"103.0"	"193.3"	"146.1"	"159.4"	"126.6"	"246.3"	"5.1"	"3390.0"	"3372.0"	"7804.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13242"	"Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1"	"0.000"	""	"35"	"9"	"20"	"8"	"221"	"25.5"	"8.65"	"3418.60"	"30.03"	"9"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"8683"	"ENSG00000111786"	"SRSF9"	"hsa:8683; Q13242; Q52LD1"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"0"	"531.3"	"461.6"	"501.2"	"508.6"	"425.1"	"449.9"	"958.8"	"0.1"	"1865.0"	"1820.9"	"3087.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKY7"	"Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1"	"0.000"	""	"26"	"6"	"16"	"6"	"258"	"27.3"	"6.40"	"3499.84"	"29.94"	"6"	"6"	""	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf15359"	"55573"	"ENSG00000091527"	"CDV3"	"B3KUC2; hsa:55573; Q96IP9; Q9UKY7"	""	""	"0"	"0"	"70.2"	"49.7"	"86.2"	"72.3"	"80.8"	"80.4"	"143.7"	"0.0"	"3353.2"	"3289.0"	"6078.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14571"	"Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2"	"0.000"	""	"3"	"8"	"16"	"5"	"2701"	"307.9"	"6.43"	"2808.52"	"29.93"	"7"	"7"	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3709"	"ENSG00000123104"	"ITPR2"	"hsa:3709; O94773; Q14571"	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"21"	"3"	"240.7"	"193.1"	"223.2"	"204.5"	"201.8"	"200.8"	"478.2"	"1.0"	"2151.2"	"2250.3"	"4750.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52701"	"DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2"	"0.000"	""	"8"	"7"	"12"	"7"	"1360"	"152.7"	"6.90"	"1730.45"	"29.91"	"5"	"7"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf00855, Pf01624, Pf05188, Pf05190, Pf05192"	"2956"	"ENSG00000116062"	"MSH6"	"B4DF41; B4E3I4; F5H2F9; hsa:2956; O43706; O43917; P52701; Q8TCX4; Q9BTB5"	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"Glioblastoma signaling pathways; Retinoblastoma gene in cancer; Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network; DNA mismatch repair"	"8"	"0"	"111.2"	"70.2"	"112.6"	"96.8"	"99.0"	"77.8"	"200.2"	"8.0"	"2049.2"	"2149.4"	"4997.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13247"	"Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2"	"0.000"	""	"19"	"6"	"17"	"2"	"344"	"39.6"	"11.43"	"2477.07"	"29.91"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6431"	"ENSG00000124193"	"SRSF6"	"B7Z6J3; E1P5W6; hsa:6431; Q13244; Q13245; Q13247; Q96J06; Q9UJB8; Q9Y3N7"	"RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"mRNA processing"	"7"	"0"	"266.4"	"184.1"	"241.3"	"266.5"	"202.4"	"213.2"	"339.6"	"2.4"	"546.6"	"545.6"	"872.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43660"	"Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1"	"0.000"	""	"20"	"6"	"9"	"6"	"514"	"57.2"	"9.17"	"1535.16"	"29.87"	"3"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	"Pf00400"	"5356"	"ENSG00000171566"	"PLRG1"	"B3KMK4; hsa:5356; O43660; Q3KQY5; Q8WUD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"103.7"	"88.7"	"125.3"	"113.0"	"121.7"	"107.3"	"287.4"	"1.9"	"1609.2"	"1727.4"	"2927.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15019"	"Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1"	"0.000"	""	"29"	"9"	"17"	"9"	"361"	"41.5"	"6.60"	"3014.39"	"29.86"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00735"	"4735"	"ENSG00000168385"	"SEPTIN2"	"B4DGE8; hsa:4735; Q14132; Q15019; Q53QU3; Q8IUK9; Q96CB0"	"Anchoring of the basal body to the plasma membrane"	"2q37 copy number variation syndrome"	"2"	"0"	"426.7"	"312.0"	"384.3"	"364.8"	"375.5"	"403.7"	"621.8"	"0.0"	"4107.8"	"3951.0"	"6779.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI48"	"Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1"	"0.000"	""	"13"	"6"	"14"	"6"	"645"	"73.5"	"8.02"	"2966.90"	"29.86"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336, Pf02938"	"55157"	"ENSG00000117593"	"DARS2"	"hsa:55157; Q6PI48"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"64.1"	"45.3"	"77.6"	"66.2"	"66.0"	"56.7"	"184.8"	"4.0"	"1274.6"	"1283.1"	"2830.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05141"	"ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7"	"0.000"	""	"33"	"10"	"21"	"4"	"298"	"32.8"	"9.69"	"3937.49"	"29.80"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"292"	"ENSG00000005022"	"SLC25A5"	"B2RCV1; hsa:292; O43350; P05141"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"5"	"6"	"447.7"	"353.4"	"441.3"	"380.8"	"425.2"	"393.2"	"634.6"	"14.0"	"5191.5"	"5628.6"	"11190.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZZ1"	"N-alpha-acetyltransferase 50 OS=Homo sapiens OX=9606 GN=NAA50 PE=1 SV=1"	"0.000"	""	"44"	"7"	"13"	"7"	"169"	"19.4"	"8.81"	"2403.61"	"29.77"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"80218"	"ENSG00000121579"	"NAA50"	"D3DN74; hsa:80218; Q68DQ1; Q9GZZ1"	""	"Metapathway biotransformation Phase I and II"	"1"	"0"	"83.2"	"51.7"	"91.5"	"83.1"	"91.7"	"89.9"	"142.6"	"12.5"	"2160.8"	"2095.3"	"4294.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24752"	"Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1"	"0.000"	""	"19"	"7"	"17"	"7"	"427"	"45.2"	"8.85"	"2763.04"	"29.76"	"6"	"7"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00108, Pf02803"	"38"	"ENSG00000075239"	"ACAT1"	"B2R6H1; G3XAB4; hsa:38; P24752; Q96FG8"	"Branched-chain amino acid catabolism; Utilization of Ketone Bodies; Synthesis of Ketone Bodies"	"Fatty acid beta-oxidation; Tryptophan metabolism; SARS-CoV-2 and COVID-19 pathway"	"6"	"0"	"193.1"	"136.5"	"207.1"	"186.1"	"199.5"	"176.0"	"302.1"	"6.4"	"3135.9"	"3187.3"	"6628.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRZ9"	"Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1"	"0.000"	""	"10"	"7"	"10"	"7"	"838"	"97.0"	"7.93"	"1402.85"	"29.72"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"3070"	"ENSG00000119969"	"HELLS"	"B2RB41; hsa:3070; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5; Q9NRZ9"	""	"Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer"	"2"	"0"	"200.0"	"173.3"	"228.0"	"218.8"	"211.7"	"205.7"	"385.1"	"10.9"	"2216.9"	"2229.9"	"4481.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4G0"	"Band 4.1-like protein 1 OS=Homo sapiens OX=9606 GN=EPB41L1 PE=1 SV=2"	"0.000"	""	"12"	"9"	"15"	"9"	"881"	"98.4"	"5.62"	"3076.00"	"29.72"	"7"	"8"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2036"	"ENSG00000088367"	"EPB41L1"	"hsa:2036; O15046; Q4VXM6; Q4VXM7; Q4VXM8; Q4VXN4; Q6ZT61; Q8IUU7; Q96CV5; Q96L65; Q9H4G0"	"Trafficking of AMPA receptors; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Neurexins and neuroligins"	"Splicing factor NOVA regulated synaptic proteins"	"5"	"0"	"94.7"	"65.2"	"96.2"	"95.8"	"97.2"	"75.5"	"225.3"	"17.7"	"2326.7"	"2258.9"	"3234.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30405"	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1"	"0.000"	""	"44"	"7"	"16"	"6"	"207"	"22.0"	"9.38"	"2165.84"	"29.46"	"5"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00160"	"10105"	"ENSG00000108179"	"PPIF"	"hsa:10105; P30405; Q2YDB7; Q5W131"	""	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"2"	"0"	"548.6"	"539.4"	"648.4"	"559.2"	"684.9"	"593.5"	"1003.4"	"1.8"	"3691.3"	"3806.5"	"6690.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0L0"	"Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3"	"0.000"	""	"29"	"7"	"12"	"6"	"249"	"27.9"	"8.62"	"1613.97"	"29.45"	"3"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9218"	"ENSG00000101558"	"VAPA"	"A6NDZ0; D3DUI3; hsa:9218; O75453; Q5U0E7; Q9P0L0; Q9UBZ2"	"Neutrophil degranulation; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane; Sphingolipid de novo biosynthesis"	"Exercise-induced circadian regulation; Cholesterol metabolism"	"5"	"1"	"115.2"	"91.4"	"144.2"	"122.5"	"115.4"	"126.0"	"245.2"	"11.9"	"3235.3"	"3152.4"	"6141.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00422"	"Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1"	"0.000"	""	"61"	"10"	"18"	"10"	"153"	"17.6"	"9.35"	"3259.58"	"29.42"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06487"	"10284"	"ENSG00000150459"	"SAP18"	"B2R494; hsa:10284; O00422; Q2TTR4; Q6IAW9; Q8N606; Q9UF14; X6RAL5"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway"	"Hedgehog signaling pathway"	"5"	"0"	"723.5"	"547.2"	"731.2"	"685.0"	"668.8"	"667.0"	"1407.3"	"2.6"	"4469.5"	"4359.9"	"8652.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99623"	"Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2"	"0.000"	""	"26"	"7"	"17"	"7"	"299"	"33.3"	"9.83"	"3545.16"	"29.33"	"7"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01145"	"11331"	"ENSG00000215021"	"PHB2"	"B4DP75; hsa:11331; Q2YDA4; Q7KYU3; Q92978; Q99623"	"Processing of SMDT1"	""	"1"	"0"	"391.6"	"329.1"	"433.9"	"362.2"	"297.4"	"429.3"	"769.6"	"3.7"	"2869.6"	"2923.9"	"4508.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ST3"	"Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2"	"0.000"	""	"8"	"8"	"11"	"8"	"1273"	"145.1"	"7.25"	"992.14"	"29.31"	"3"	"8"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02671, Pf08295, Pf16879"	"25942"	"ENSG00000169375"	"SIN3A"	"B2RNS5; hsa:25942; Q8N8N4; Q8NC83; Q8WV18; Q96L98; Q96ST3; Q9UFQ1"	"Factors involved in megakaryocyte development and platelet production; NoRC negatively regulates rRNA expression; MECP2 regulates neuronal receptors and channels; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SUMOylation of transcription cofactors; Cytoprotection by HMOX1; MECP2 regulates transcription of neuronal ligands; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Regulation of lipid metabolism by PPARalpha; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; Loss of MECP2 binding ability to 5mC-DNA"	"Androgen receptor signaling pathway; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Transcription co-factors SKI and SKIL protein partners; Hedgehog signaling pathway; 15q11q13 copy number variation"	"18"	"0"	"163.7"	"119.5"	"150.7"	"154.9"	"138.8"	"155.6"	"301.7"	"10.0"	"1723.7"	"1749.9"	"4250.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14927"	"Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2"	"0.000"	""	"56"	"5"	"12"	"5"	"111"	"13.5"	"8.78"	"2912.60"	"29.26"	"5"	"5"	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02271"	"7381"	"ENSG00000156467"	"UQCRB"	"E5RJU0; hsa:7381; P14927; Q6FGD1"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"208.2"	"207.8"	"231.9"	"212.4"	"269.8"	"242.2"	"489.4"	"6.3"	"2596.0"	"2500.7"	"4888.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3A5"	"Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4"	"0.000"	""	"47"	"12"	"18"	"11"	"250"	"28.7"	"8.75"	"3422.86"	"29.20"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity"	"Pf01172, Pf09377, Pf20268"	"51119"	"ENSG00000126524"	"SBDS"	"A8K0P4; hsa:51119; Q96FX0; Q9NV53; Q9Y3A5"	""	"Genetic causes of porto-sinusoidal vascular disease"	"1"	"1"	"327.7"	"254.5"	"335.7"	"309.3"	"272.3"	"313.7"	"553.6"	"3.0"	"5113.7"	"5072.7"	"10498.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62140"	"Serine/threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3"	"0.000"	""	"22"	"6"	"11"	"1"	"327"	"37.2"	"6.19"	"2189.24"	"29.11"	"5"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5500"	"ENSG00000213639"	"PPP1CB"	"B2R5V4; D6W565; hsa:5500; P37140; P62140; Q5U087; Q6FG45"	"RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Triglyceride catabolism; Regulation of PLK1 Activity at G2/M Transition; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PAKs; Downregulation of TGF-beta receptor signaling"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Airway smooth muscle cell contraction; Neuroinflammation and glutamatergic signaling; G13 signaling pathway"	"18"	"0"	"17.0"	"8.5"	"17.1"	"17.4"	"20.2"	"19.8"	"39.3"	"0.0"	"309.0"	"323.3"	"633.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92733"	"Proline-rich protein PRCC OS=Homo sapiens OX=9606 GN=PRCC PE=1 SV=1"	"0.000"	""	"16"	"6"	"9"	"6"	"491"	"52.4"	"5.10"	"1229.88"	"29.11"	"3"	"5"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf10253"	"5546"	"ENSG00000143294"	"PRCC"	"A8K1F7; hsa:5546; O00665; O00724; Q5SZ06; Q92733"	"mRNA Splicing - Major Pathway"	"Type 2 papillary renal cell carcinoma; IL-18 signaling pathway"	"3"	"0"	"193.2"	"156.2"	"157.4"	"178.2"	"193.6"	"184.9"	"388.1"	"6.0"	"1717.9"	"1820.8"	"3347.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31939"	"Bifunctional purine biosynthesis protein PURH OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3"	"0.000"	""	"20"	"10"	"16"	"10"	"592"	"64.6"	"6.71"	"2115.28"	"29.11"	"6"	"9"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf01808, Pf02142"	"471"	"ENSG00000138363"	"ATIC"	"A8K202; E9PBU3; hsa:471; P31939; Q13856; Q53S28"	"Signaling by ALK fusions and activated point mutants; Purine ribonucleoside monophosphate biosynthesis"	"One-carbon metabolism"	"3"	"0"	"88.8"	"76.8"	"134.1"	"107.2"	"119.6"	"86.9"	"186.6"	"10.1"	"2214.9"	"2491.7"	"8740.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55010"	"Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2"	"0.000"	""	"18"	"7"	"10"	"7"	"431"	"49.2"	"5.58"	"290.71"	"29.10"	"1"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01873, Pf02020"	"1983"	"ENSG00000100664"	"EIF5"	"hsa:1983; P55010; Q53XB3; Q9H5N2; Q9UG48"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"4"	"0"	"97.2"	"74.5"	"101.8"	"94.1"	"109.4"	"83.7"	"190.7"	"8.3"	"3385.1"	"3571.2"	"11082.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04637"	"Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4"	"0.000"	""	"16"	"6"	"15"	"6"	"393"	"43.6"	"6.79"	"2821.41"	"29.08"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00870, Pf07710, Pf08563, Pf18521"	"7157"	"ENSG00000141510"	"TP53"	"hsa:7157; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Autodegradation of the E3 ubiquitin ligase COP1; Ub-specific processing proteases; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Regulation of TP53 Degradation; TP53 Regulates Transcription of Death Receptors and Ligands; Oxidative Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-4 and Interleukin-13 signaling; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of TP53 Activity through Methylation; G2/M DNA damage checkpoint; Regulation of NF-kappa B signaling; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors; Ovarian tumor domain proteases; Pyroptosis; SUMOylation of transcription factors; Regulation of TP53 Expression; RUNX3 regulates CDKN1A transcription; Activation of NOXA and translocation to mitochondria; Formation of Senescence-Associated Heterochromatin Foci (SAHF); PI5P Regulates TP53 Acetylation; Transcriptional  activation of  cell cycle inhibitor p21 ; Loss of function of TP53 in cancer due to loss of tetramerization ability"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Fluoropyrimidine activity; TP53 network; Folate metabolism; Apoptosis modulation and signaling; Cell cycle; Metastatic brain tumor; Glioblastoma signaling pathways; Gastric cancer network 2; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Amyotrophic lateral sclerosis (ALS); ATM signaling pathway; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Copper homeostasis; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; lncRNA-mediated mechanisms of therapeutic resistance; MAPK signaling pathway; miRNA regulation of p53 pathway in prostate cancer; Wnt signaling pathway and pluripotency; Endometrial cancer; PI3K-Akt signaling pathway; Caloric restriction and aging; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; Ferroptosis; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; MicroRNA network associated with chronic lymphocytic leukemia; G1 to S cell cycle control; Measles virus infection; 22q11.2 copy number variation syndrome; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Unfolded protein response; 16p11.2 proximal deletion syndrome; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; TCA cycle in senescence; Pleural mesothelioma; Lipid metabolism in senescent cells; DYRK1A involvement regarding cell proliferation in brain development; 2q37 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; DNA damage response; DNA damage response (only ATM dependent)"	"107"	"0"	"148.9"	"122.9"	"152.2"	"139.4"	"155.8"	"153.0"	"377.1"	"0.2"	"2087.7"	"2001.0"	"4730.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55072"	"Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4"	"0.000"	""	"14"	"9"	"17"	"9"	"806"	"89.3"	"5.26"	"3762.73"	"29.08"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf09336, Pf17862"	"7415"	"ENSG00000165280"	"VCP"	"B2R5T8; hsa:7415; P55072; Q0V924; Q2TAI5; Q969G7; Q9UCD5"	"Neutrophil degranulation; E3 ubiquitin ligases ubiquitinate target proteins; ABC-family proteins mediated transport; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Defective CFTR causes cystic fibrosis; Neddylation; KEAP1-NFE2L2 pathway; Aggrephagy; Attachment and Entry; Attachment and Entry; Ovarian tumor domain proteases; Josephin domain DUBs; Protein methylation; RHOH GTPase cycle; HSF1 activation; Translesion Synthesis by POLH; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Alstrom syndrome; Clock-controlled autophagy in bone metabolism"	"20"	"0"	"752.9"	"594.5"	"814.1"	"794.3"	"645.9"	"676.0"	"1008.2"	"0.0"	"2456.1"	"2325.7"	"3837.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57721"	"Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2"	"0.000"	""	"20"	"7"	"13"	"1"	"371"	"39.4"	"8.07"	"2443.49"	"28.99"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"54039"	"ENSG00000183570"	"PCBP3"	"A8MPS2; A8MQ26; B7WNN9; B7WPC1; hsa:54039; P57721; Q8N9K6; Q96EP6"	""	""	"0"	"0"	"6.0"	"4.1"	"12.1"	"9.6"	"7.0"	"10.8"	"26.2"	"0.0"	"344.2"	"352.2"	"701.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83731"	"60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1"	"0.000"	""	"46"	"9"	"18"	"9"	"157"	"17.8"	"11.25"	"3224.80"	"28.98"	"8"	"8"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01246"	"6152"	"ENSG00000114391"	"RPL24"	"B2R4Y3; hsa:6152; P38663; P83731; Q6IBS3"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"622.9"	"524.1"	"596.9"	"541.7"	"528.5"	"572.0"	"2193.4"	"12.1"	"5244.1"	"5045.5"	"9293.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15143"	"Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B PE=1 SV=3"	"0.000"	""	"18"	"5"	"13"	"4"	"372"	"40.9"	"8.35"	"1907.98"	"28.97"	"3"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400"	"10095"	"ENSG00000130429"	"ARPC1B"	"hsa:10095; O15143; Q9BU00"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection; Microglia pathogen phagocytosis pathway"	"6"	"0"	"152.4"	"99.1"	"145.3"	"133.9"	"145.9"	"124.0"	"208.5"	"5.7"	"2885.3"	"2813.6"	"6570.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RP9"	"Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2"	"0.000"	""	"9"	"6"	"13"	"6"	"751"	"83.4"	"7.01"	"2518.85"	"28.92"	"6"	"6"	"protein metabolism;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"85476"	"ENSG00000168827"	"GFM1"	"A6NCI9; B2RCB9; B3KRW1; hsa:85476; Q6GTN2; Q96RP9; Q96T39"	"Mitochondrial translation elongation"	""	"1"	"0"	"50.5"	"34.1"	"76.9"	"56.3"	"62.2"	"50.2"	"101.9"	"0.6"	"1311.9"	"1326.4"	"3063.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05682"	"Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3"	"0.000"	""	"13"	"10"	"18"	"10"	"793"	"93.2"	"5.66"	"3701.32"	"28.87"	"9"	"7"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02029"	"800"	"ENSG00000122786"	"CALD1"	"A8K0X1; hsa:800; Q05682; Q13978; Q13979; Q14741; Q14742; Q9UD91"	"Smooth Muscle Contraction"	"Myometrial relaxation and contraction pathways"	"2"	"0"	"384.7"	"307.0"	"379.1"	"383.9"	"323.4"	"373.8"	"764.1"	"8.2"	"4038.4"	"3957.6"	"7143.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15170"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1"	"0.000"	""	"19"	"9"	"15"	"4"	"499"	"55.7"	"5.62"	"2354.11"	"28.82"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"2935"	"ENSG00000103342"	"GSPT1"	"hsa:2935; J3KQG6; P15170; Q96GF2"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	""	"4"	"6"	"106.1"	"80.6"	"118.2"	"119.3"	"108.7"	"119.9"	"224.7"	"21.4"	"3611.4"	"3616.1"	"8323.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60739"	"Eukaryotic translation initiation factor 1b OS=Homo sapiens OX=9606 GN=EIF1B PE=1 SV=2"	"0.000"	""	"29"	"4"	"11"	"2"	"113"	"12.8"	"7.37"	"2240.76"	"28.74"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10289"	"ENSG00000114784"	"EIF1B"	"hsa:10289; O60739; Q9UQF8"	""	""	"0"	"3"	"46.0"	"38.9"	"62.4"	"47.5"	"51.9"	"55.6"	"160.0"	"11.6"	"2059.8"	"2116.0"	"4121.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25098"	"Beta-adrenergic receptor kinase 1 OS=Homo sapiens OX=9606 GN=GRK2 PE=1 SV=2"	"0.000"	""	"14"	"7"	"11"	"7"	"689"	"79.5"	"7.28"	"1719.25"	"28.72"	"5"	"6"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00615"	"156"	"ENSG00000173020"	"GRK2"	"B0ZBE1; hsa:156; P25098; Q13837; Q6GTT3"	"Cargo recognition for clathrin-mediated endocytosis; G alpha (q) signalling events; Activation of SMO; G alpha (s) signalling events; Calmodulin induced events"	"Chemokine signaling pathway; Hedgehog signaling pathway; Hedgehog signaling pathway"	"8"	"0"	"72.2"	"56.2"	"89.4"	"69.7"	"77.8"	"71.0"	"157.2"	"9.9"	"2241.9"	"2319.3"	"5187.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62857"	"40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1"	"0.000"	""	"57"	"5"	"16"	"5"	"69"	"7.8"	"10.70"	"3593.08"	"28.70"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01200"	"6234"	"ENSG00000233927"	"RPS28"	"hsa:6234; P25112; P62857"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"232.9"	"181.6"	"323.8"	"236.7"	"244.4"	"192.0"	"578.3"	"0.0"	"2131.0"	"1996.6"	"4085.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98175"	"RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3"	"0.000"	""	"9"	"7"	"10"	"7"	"930"	"103.5"	"5.97"	"1475.59"	"28.68"	"3"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"8241"	"ENSG00000182872"	"RBM10"	"A0A0A0MR66; C4AM81; hsa:8241; P98175; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	""	"2"	"0"	"302.7"	"223.7"	"280.4"	"282.4"	"267.2"	"261.0"	"545.2"	"11.0"	"2421.7"	"2357.1"	"4922.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15291"	"Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2"	"0.000"	""	"17"	"7"	"13"	"7"	"538"	"59.1"	"5.10"	"1596.11"	"28.65"	"4"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"5929"	"ENSG00000117222"	"RBBP5"	"A8K272; hsa:5929; Q15291; Q7Z6D8; Q8NDZ7"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"Kleefstra syndrome"	"8"	"0"	"104.2"	"79.5"	"121.4"	"95.8"	"105.3"	"118.9"	"186.7"	"4.6"	"1526.3"	"1652.6"	"3914.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13217"	"DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1"	"0.000"	""	"19"	"9"	"15"	"9"	"504"	"57.5"	"6.15"	"2470.43"	"28.63"	"7"	"7"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00226, Pf00515, Pf13181, Pf13432"	"5611"	"ENSG00000102580"	"DNAJC3"	"hsa:5611; Q13217; Q86WT9; Q8N4N2"	"Neutrophil degranulation; Viral mRNA Translation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response"	"6"	"0"	"185.4"	"149.1"	"216.6"	"202.1"	"189.3"	"208.8"	"341.6"	"6.0"	"3625.0"	"3706.5"	"7210.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY77"	"Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2"	"0.000"	""	"24"	"6"	"10"	"6"	"421"	"46.1"	"9.99"	"1683.35"	"28.61"	"4"	"6"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"84271"	"ENSG00000100227"	"POLDIP3"	"A8K6F8; A8K6V9; hsa:84271; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9BY77; Q9NSP5; Q9NSP6"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"3"	"0"	"254.1"	"168.3"	"225.1"	"220.0"	"220.9"	"209.4"	"427.1"	"10.0"	"1302.9"	"1187.2"	"2617.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61981"	"14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2"	"0.000"	""	"37"	"8"	"18"	"4"	"247"	"28.3"	"4.89"	"3492.41"	"28.58"	"7"	"8"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00244"	"7532"	"ENSG00000170027"	"YWHAG"	"hsa:7532; O70457; P35214; P61981; Q6FH52; Q9UDP2; Q9UN99"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Prolactin signaling pathway; Myometrial relaxation and contraction pathways; Disruption of postsynaptic signaling by CNV; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"21"	"0"	"171.1"	"129.7"	"163.9"	"170.4"	"136.5"	"158.9"	"300.6"	"0.2"	"694.4"	"671.3"	"1190.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15424"	"Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4"	"0.000"	""	"10"	"9"	"18"	"6"	"915"	"102.6"	"5.47"	"3065.16"	"28.57"	"8"	"8"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"6294"	"ENSG00000160633"	"SAFB"	"A0AV56; B7Z5B6; B7ZLP6; F5H0H3; hsa:6294; O60406; Q15424; Q59HH8"	"SUMOylation of transcription cofactors"	"Interleukin-1 (IL-1) structural pathway"	"2"	"3"	"1118.3"	"917.5"	"1164.9"	"1105.9"	"801.8"	"947.6"	"2554.3"	"3.0"	"4837.0"	"5056.0"	"10667.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30533"	"Alpha-2-macroglobulin receptor-associated protein OS=Homo sapiens OX=9606 GN=LRPAP1 PE=1 SV=1"	"0.000"	""	"29"	"10"	"15"	"10"	"357"	"41.4"	"8.78"	"2051.79"	"28.52"	"7"	"8"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf06400, Pf06401"	"4043"	"ENSG00000163956"	"LRPAP1"	"D3DVR9; hsa:4043; P30533; Q2M310; Q53HQ3; Q53HS6"	""	"Cholesterol metabolism"	"1"	"0"	"260.2"	"202.5"	"272.5"	"260.7"	"263.1"	"249.4"	"607.3"	"2.5"	"6584.2"	"6518.5"	"10367.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15637"	"Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4"	"0.000"	""	"14"	"6"	"12"	"6"	"639"	"68.3"	"8.98"	"1893.81"	"28.45"	"4"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00098, Pf16275"	"7536"	"ENSG00000168066"	"SF1"	"B7Z1Q1; C9JJE2; hsa:7536; Q14818; Q14819; Q15637; Q15913; Q8IY00; Q92744; Q92745; Q969H7; Q9BW01; Q9UEI0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"363.0"	"290.0"	"378.4"	"331.4"	"311.2"	"357.1"	"700.8"	"4.9"	"2776.6"	"2739.1"	"4595.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3I0"	"RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1"	"0.000"	""	"16"	"9"	"17"	"9"	"505"	"55.2"	"7.23"	"2509.31"	"28.44"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01139"	"51493"	"ENSG00000100220"	"RTCB"	"B2R6A8; hsa:51493; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3; Q9Y3I0"	"tRNA processing in the nucleus"	"Unfolded protein response"	"2"	"0"	"432.5"	"375.5"	"455.6"	"417.2"	"345.6"	"360.8"	"913.3"	"7.8"	"3884.6"	"3711.7"	"7033.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60934"	"Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1"	"0.000"	""	"11"	"7"	"11"	"7"	"754"	"84.9"	"6.90"	"1828.68"	"28.32"	"4"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08599, Pf16508"	"4683"	"ENSG00000104320"	"NBN"	"B2R626; B2RNC5; hsa:4683; O60672; O60934; Q32NF7; Q53FM6; Q63HR6; Q7LDM2"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; DNA damage response"	"29"	"0"	"230.0"	"151.6"	"221.5"	"196.4"	"193.6"	"193.5"	"305.7"	"2.2"	"2824.3"	"2753.2"	"6500.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z6E9"	"E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1"	"0.000"	""	"4"	"7"	"15"	"7"	"1792"	"201.4"	"9.64"	"2917.59"	"28.31"	"7"	"6"	"protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04564, Pf08783, Pf13696"	"5930"	"ENSG00000122257"	"RBBP6"	"hsa:5930; Q147T5; Q15290; Q6DKH4; Q6P4C2; Q6YNC9; Q7Z6E8; Q7Z6E9; Q8N0V2; Q96PH3; Q9H3I8; Q9H5M5; Q9NPX4"	"RHOBTB1 GTPase cycle; Antigen processing: Ubiquitination & Proteasome degradation"	""	"2"	"0"	"242.4"	"164.3"	"248.3"	"222.7"	"214.3"	"254.3"	"504.3"	"1.3"	"2926.6"	"2859.7"	"6023.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95292"	"Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3"	"0.000"	""	"24"	"5"	"11"	"4"	"243"	"27.2"	"7.30"	"2423.43"	"28.29"	"4"	"5"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9217"	"ENSG00000124164"	"VAPB"	"A2A2F2; hsa:9217; O95292; O95293; Q9P0H0"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; Sphingolipid de novo biosynthesis"	"Ciliary landscape"	"7"	"0"	"32.6"	"24.6"	"40.4"	"37.4"	"38.0"	"37.7"	"105.2"	"3.5"	"1302.4"	"1208.0"	"2499.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95202"	"Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1"	"0.000"	""	"11"	"7"	"11"	"7"	"739"	"83.3"	"6.70"	"1423.36"	"28.29"	"4"	"7"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;translation activity;other molecular function"	"Pf07766"	"3954"	"ENSG00000168924"	"LETM1"	"B4DED2; hsa:3954; O95202; Q9UF65"	"RHOG GTPase cycle; Mitochondrial calcium ion transport"	"4p16.3 copy number variation"	"3"	"0"	"189.5"	"121.6"	"198.4"	"183.8"	"177.0"	"187.2"	"268.4"	"2.6"	"1903.0"	"1918.8"	"4511.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53396"	"ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3"	"0.000"	""	"8"	"8"	"16"	"8"	"1101"	"120.8"	"7.33"	"2532.23"	"28.23"	"7"	"8"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00285, Pf00549, Pf02629, Pf16114"	"47"	"ENSG00000131473"	"ACLY"	"B4DIM0; B4E3P0; hsa:47; P53396; Q13037; Q9BRL0"	"Neutrophil degranulation; ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Fatty acid biosynthesis; Amino acid metabolism; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer"	"10"	"0"	"199.1"	"180.2"	"241.1"	"194.3"	"206.2"	"166.8"	"472.8"	"6.9"	"2728.0"	"2775.0"	"6456.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62495"	"Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3"	"0.000"	""	"17"	"6"	"14"	"6"	"437"	"49.0"	"5.71"	"2147.38"	"28.18"	"5"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"2107"	"ENSG00000120705"	"ETF1"	"B2R6B4; D3DQC1; hsa:2107; P46055; P62495; Q5M7Z7; Q96CG1"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Translation factors"	"5"	"0"	"60.7"	"39.7"	"65.9"	"57.7"	"61.5"	"65.0"	"114.0"	"4.6"	"2597.1"	"2609.9"	"5374.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16836"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3"	"0.000"	""	"30"	"10"	"17"	"10"	"314"	"34.3"	"8.85"	"2857.87"	"28.16"	"8"	"7"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00725, Pf02737"	"3033"	"ENSG00000138796"	"HADH"	"hsa:3033; J3KQ17; O00324; O00397; O00753; Q16836; Q4W5B4"	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"11"	"0"	"625.7"	"396.3"	"512.3"	"522.5"	"566.0"	"546.1"	"870.9"	"0.0"	"6277.2"	"6216.0"	"10967.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45973"	"Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1"	"0.000"	""	"42"	"7"	"15"	"6"	"191"	"22.2"	"5.86"	"3140.55"	"28.12"	"7"	"6"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"23468"	"ENSG00000094916"	"CBX5"	"B2R8T9; hsa:23468; P45973"	"SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6; Factors involved in megakaryocyte development and platelet production"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; 22q11.2 copy number variation syndrome"	"5"	"1"	"84.2"	"80.7"	"107.7"	"82.7"	"88.7"	"78.8"	"174.6"	"3.0"	"1694.6"	"1787.9"	"3790.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Q3"	"Glutathione S-transferase kappa 1 OS=Homo sapiens OX=9606 GN=GSTK1 PE=1 SV=3"	"0.000"	""	"24"	"5"	"12"	"5"	"226"	"25.5"	"8.41"	"2693.15"	"28.12"	"5"	"5"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf01323"	"373156"	"ENSG00000197448"	"GSTK1"	"B4DIH1; B4DSY2; hsa:373156; Q6P4H0; Q7Z520; Q9P1S4; Q9Y2Q3"	"Peroxisomal protein import; Glutathione conjugation"	"Metapathway biotransformation Phase I and II"	"3"	"0"	"32.8"	"26.6"	"42.3"	"34.8"	"47.2"	"50.6"	"57.2"	"5.9"	"1677.4"	"1675.4"	"3783.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JWF2"	"Guanine nucleotide-binding protein G(s) subunit alpha isoforms XLas OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=2"	"0.000"	""	"9"	"8"	"15"	"7"	"1037"	"111.0"	"5.03"	"2206.59"	"28.03"	"7"	"7"	"cell adhesion;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00503"	"2778"	"ENSG00000087460"	"GNAS"	"A2A2S3; E1P5G3; O75684; O75685; Q5JW67; Q5JWF1; Q5JWF2; Q9NY42"	"G alpha (i) signalling events; G alpha (z) signalling events; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Prostacyclin signalling through prostacyclin receptor; Glucagon-type ligand receptors; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation in glucagon signalling; Hedgehog 'off' state"	"Thyroid stimulating hormone (TSH) signaling pathway; Endothelin pathways; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; Thermogenesis; Hippo signaling regulation pathways; Purinergic signaling; GPR143 in melanocytes and retinal pigment epithelium cells; Prostaglandin and leukotriene metabolism in senescence ; Primary ovarian insufficiency; Prostaglandin and leukotriene metabolism in senescence ; Calcium regulation in cardiac cells; Estrogen signaling pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"28"	"1"	"95.8"	"58.7"	"137.9"	"108.0"	"124.3"	"83.9"	"235.1"	"41.0"	"2091.2"	"2007.1"	"4256.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92621"	"Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3"	"0.000"	""	"5"	"8"	"14"	"8"	"2012"	"227.8"	"6.19"	"2250.63"	"28.02"	"6"	"8"	"cell organization and biogenesis;transport"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf11894"	"23165"	"ENSG00000155561"	"NUP205"	"A6H8X3; hsa:23165; Q86YC1; Q92621"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"29"	"0"	"112.1"	"99.1"	"122.3"	"121.2"	"89.8"	"102.0"	"202.7"	"9.6"	"1996.9"	"1938.7"	"4290.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12236"	"ADP/ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4"	"0.000"	""	"26"	"8"	"18"	"2"	"298"	"32.8"	"9.74"	"3008.79"	"27.99"	"7"	"7"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"293"	"ENSG00000169100"	"SLC25A6"	"hsa:293; P12236; Q96C49"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Mitochondrial protein import; Influenza Virus Induced Apoptosis; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"7"	"0"	"37.7"	"30.6"	"52.2"	"36.8"	"49.9"	"40.2"	"107.4"	"0.1"	"928.7"	"968.1"	"1872.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13442"	"28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1"	"0.000"	""	"30"	"6"	"14"	"6"	"181"	"20.6"	"8.87"	"2757.75"	"27.99"	"6"	"6"	"signal transduction"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf10252"	"11333"	"ENSG00000106244"	"PDAP1"	"D6W5S5; hsa:11333; Q13442; Q92906"	"Neutrophil degranulation"	""	"1"	"0"	"339.0"	"235.6"	"326.3"	"303.1"	"261.5"	"293.1"	"512.3"	"1.8"	"3758.9"	"3545.2"	"7419.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06730"	"Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2"	"0.000"	""	"37"	"8"	"16"	"8"	"217"	"25.1"	"6.15"	"2487.79"	"27.89"	"8"	"8"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"1977"	"ENSG00000151247"	"EIF4E"	"B7Z6V1; D6RCQ6; hsa:1977; P06730; Q96E95"	"Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling"	"Translation factors; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prader-Willi and Angelman syndrome; PI3K-Akt signaling pathway; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Hypertrophy model; Interferon type I signaling pathways"	"31"	"0"	"63.3"	"44.1"	"78.6"	"57.1"	"77.7"	"75.9"	"114.7"	"3.4"	"3137.0"	"3131.3"	"6824.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SRE5"	"Nucleoporin NUP188 homolog OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1"	"0.000"	""	"6"	"7"	"13"	"7"	"1749"	"195.9"	"6.73"	"3167.53"	"27.88"	"6"	"7"	"transport"	"cytosol;nucleus"	"other molecular function"	"Pf10487"	"23511"	"ENSG00000095319"	"NUP188"	"hsa:23511; Q14675; Q2TA87; Q5SRE5; Q7Z3K8; Q8IWF1"	"Vpr-mediated nuclear import of PICs; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; SUMOylation of chromatin organization proteins; HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"55.8"	"43.1"	"57.3"	"65.4"	"58.6"	"53.7"	"97.0"	"2.1"	"619.6"	"646.2"	"1154.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY18"	"Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2"	"0.000"	""	"8"	"7"	"12"	"7"	"1101"	"128.7"	"8.38"	"2501.05"	"27.85"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"23137"	"ENSG00000198887"	"SMC5"	"A6NM81; hsa:23137; O60335; Q05D92; Q5VZ60; Q8IY18; Q96SB9"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"42.0"	"33.8"	"48.5"	"54.2"	"52.8"	"43.0"	"144.1"	"0.7"	"1282.8"	"1287.0"	"3022.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L576"	"Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1"	"0.000"	""	"7"	"8"	"17"	"2"	"1253"	"145.1"	"6.90"	"2733.85"	"27.78"	"8"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf05994, Pf07159"	"23191"	"ENSG00000273749; ENSG00000288461"	"CYFIP1"	"A8K6D9; hsa:23191; Q14467; Q5IED0; Q6ZSX1; Q7L576; Q9BSD9; Q9BVC7"	"Neutrophil degranulation; VEGFA-VEGFR2 Pathway; RAC3 GTPase cycle; RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; G13 signaling pathway"	"15"	"6"	"139.3"	"107.3"	"141.3"	"129.2"	"140.8"	"118.6"	"216.1"	"7.2"	"1466.0"	"1409.4"	"2716.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXF1"	"Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1"	"0.000"	""	"13"	"6"	"11"	"6"	"523"	"58.7"	"6.67"	"1485.33"	"27.68"	"5"	"5"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00076, Pf08075"	"55269"	"ENSG00000121390"	"PSPC1"	"hsa:55269; Q5JTQ3; Q8NCZ9; Q8WXE8; Q8WXF1; Q9NV36"	""	""	"0"	"0"	"235.4"	"195.5"	"244.8"	"199.0"	"222.2"	"226.9"	"597.3"	"0.0"	"2514.5"	"2677.2"	"4666.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16576"	"Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1"	"0.000"	""	"20"	"8"	"15"	"2"	"425"	"47.8"	"5.05"	"2624.80"	"27.67"	"7"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5931"	"ENSG00000102054"	"RBBP7"	"hsa:5931; Q16576; Q5JP00"	"HCMV Early Events; Neddylation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; RMTs methylate histone arginines; PKMTs methylate histone lysines; HATs acetylate histones; RNA Polymerase I Transcription Initiation; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"20"	"0"	"78.0"	"83.9"	"53.5"	"71.2"	"66.2"	"52.2"	"147.3"	"3.5"	"567.8"	"539.0"	"992.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37802"	"Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3"	"0.000"	""	"41"	"6"	"10"	"6"	"199"	"22.4"	"8.25"	"1878.45"	"27.56"	"4"	"6"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00307, Pf00402"	"8407"	"ENSG00000158710"	"TAGLN2"	"E9KL39; hsa:8407; P37802; Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0"	"Platelet degranulation"	""	"1"	"0"	"38.2"	"42.5"	"64.2"	"71.0"	"57.7"	"40.8"	"73.3"	"3.0"	"636.1"	"608.5"	"2344.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23528"	"Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3"	"0.000"	""	"43"	"7"	"13"	"7"	"166"	"18.5"	"8.09"	"3084.67"	"27.50"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1072"	"ENSG00000172757"	"CFL1"	"B3KUQ1; hsa:1072; P23528; Q53Y87; Q9UCA2"	"Platelet degranulation ; Regulation of actin dynamics for phagocytic cup formation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; EPHB-mediated forward signaling; Sema3A PAK dependent Axon repulsion; RHO GTPases Activate ROCKs"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"15"	"0"	"180.8"	"150.3"	"293.7"	"217.1"	"200.6"	"154.8"	"392.2"	"5.5"	"2081.8"	"2087.9"	"4404.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZF1"	"Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3"	"0.000"	""	"9"	"6"	"13"	"6"	"889"	"101.1"	"6.96"	"2379.06"	"27.48"	"6"	"6"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114882"	"ENSG00000091039"	"OSBPL8"	"A8K1T2; E9PE66; E9PE68; hsa:114882; Q52LQ3; Q68D75; Q8WXP8; Q9BZF1; Q9P277"	"Acyl chain remodelling of PS"	""	"1"	"0"	"63.6"	"55.8"	"77.0"	"70.4"	"64.7"	"76.1"	"113.9"	"12.5"	"1409.1"	"1567.0"	"2947.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14CX7"	"N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1"	"0.000"	""	"10"	"9"	"15"	"9"	"972"	"112.2"	"6.64"	"2604.11"	"27.42"	"7"	"8"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf09797"	"80018"	"ENSG00000111300"	"NAA25"	"A0JLU7; hsa:80018; Q14CX7; Q6MZH1; Q7Z4N6; Q9H911"	""	""	"0"	"0"	"77.5"	"78.7"	"121.6"	"115.6"	"124.5"	"110.5"	"264.2"	"17.8"	"3242.8"	"3174.4"	"6712.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX12"	"Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2"	"0.000"	""	"8"	"7"	"16"	"7"	"1150"	"132.7"	"5.76"	"2815.28"	"27.38"	"7"	"7"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf14443, Pf14444, Pf19256, Pf19257"	"55749"	"ENSG00000060339"	"CCAR1"	"A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; hsa:55749; Q32NE3; Q5EBM3; Q5VUP6; Q6PIZ0; Q6X935; Q8IX12; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"311.8"	"241.0"	"333.6"	"286.8"	"243.1"	"330.1"	"675.3"	"3.4"	"1955.0"	"1899.1"	"3950.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04917"	"14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4"	"0.000"	""	"25"	"6"	"14"	"3"	"246"	"28.2"	"4.84"	"2089.72"	"27.37"	"4"	"6"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00244"	"7533"	"ENSG00000128245"	"YWHAH"	"hsa:7533; Q04917"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"Cell cycle; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"0"	"207.2"	"175.0"	"178.8"	"168.9"	"183.8"	"197.5"	"383.7"	"1.7"	"1368.7"	"1432.7"	"2152.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14566"	"DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1"	"0.000"	""	"11"	"6"	"10"	"6"	"821"	"92.8"	"5.41"	"1892.20"	"27.33"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855, Pf18263"	"4175"	"ENSG00000076003"	"MCM6"	"B2R6H2; hsa:4175; Q13504; Q14566; Q99859"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"11"	"0"	"114.3"	"78.6"	"118.7"	"99.6"	"103.9"	"111.3"	"164.8"	"5.0"	"864.9"	"870.4"	"2542.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62937"	"Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2"	"0.000"	""	"39"	"6"	"12"	"5"	"165"	"18.0"	"7.81"	"1467.75"	"27.28"	"3"	"6"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00160"	"5478"	"ENSG00000196262"	"PPIA"	"A8K220; hsa:5478; P05092; P62937; Q3KQW3; Q567Q0; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9; Q9UC61"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Budding and maturation of HIV virion; Platelet degranulation ; Basigin interactions; SARS-CoV-1 activates/modulates innate immune responses; Integration of provirus; APOBEC3G mediated resistance to HIV-1 infection; Calcineurin activates NFAT; Binding and entry of HIV virion; Assembly Of The HIV Virion; Uncoating of the HIV Virion; Minus-strand DNA synthesis; Plus-strand DNA synthesis"	"Prolactin signaling pathway"	"16"	"0"	"233.9"	"211.5"	"409.8"	"286.0"	"204.0"	"204.2"	"440.0"	"17.4"	"1757.4"	"1596.5"	"8163.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13620"	"Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4"	"0.000"	""	"9"	"7"	"15"	"3"	"913"	"103.9"	"7.37"	"2235.27"	"27.23"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8450"	"ENSG00000158290"	"CUL4B"	"B1APK5; B3KVX4; B7Z5K8; hsa:8450; Q13620; Q6PIE4; Q6UP07; Q7Z673; Q9BY37; Q9UEB7; Q9UED7"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"Mesodermal commitment pathway; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"13"	"4"	"154.4"	"100.3"	"174.0"	"164.3"	"160.2"	"156.9"	"241.3"	"9.9"	"3425.4"	"3461.2"	"7421.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26373"	"60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4"	"0.000"	""	"40"	"10"	"17"	"10"	"211"	"24.2"	"11.65"	"2975.84"	"27.23"	"8"	"9"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01294"	"6137"	"ENSG00000167526"	"RPL13"	"B4DLX3; F5H1S2; hsa:6137; P26373; Q3KQT8; Q567Q8; Q9BPX0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"878.3"	"721.6"	"824.5"	"817.3"	"743.2"	"832.5"	"2894.8"	"5.0"	"5623.6"	"5716.1"	"9111.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y237"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1"	"0.000"	""	"46"	"7"	"17"	"7"	"131"	"13.8"	"9.77"	"2758.10"	"27.19"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13616"	"5303"	"ENSG00000102309"	"PIN4"	"A8E0G6; B3KXM0; F5H1P5; hsa:5303; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6; Q6IRW4; Q9Y237"	""	""	"0"	"0"	"192.5"	"176.0"	"368.4"	"243.0"	"198.8"	"334.6"	"1156.1"	"2.4"	"3020.9"	"2817.3"	"5100.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41214"	"Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3"	"0.000"	""	"14"	"6"	"11"	"6"	"584"	"64.7"	"7.65"	"1477.07"	"27.16"	"4"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01253, Pf17832"	"1939"	"ENSG00000143486"	"EIF2D"	"hsa:1939; P41214; Q5SY40; Q8IXV3; Q96DG3; Q96TG7; Q9NR27; Q9NSN0; Q9NV18; Q9NZ21"	""	""	"0"	"0"	"143.9"	"101.8"	"180.2"	"172.1"	"169.2"	"120.2"	"196.3"	"2.4"	"1326.0"	"1259.9"	"2755.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54819"	"Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2"	"0.000"	""	"45"	"7"	"11"	"7"	"239"	"26.5"	"7.81"	"2088.55"	"27.15"	"4"	"7"	"other metabolic processes"	"cytoskeleton;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"204"	"ENSG00000004455"	"AK2"	"A8K6L1; B4DHH7; B4DL64; hsa:204; P54819; Q16856; Q5EB54; Q5TIF7; Q8TCY2; Q8TCY3"	"Interconversion of nucleotide di- and triphosphates"	""	"1"	"0"	"54.7"	"44.4"	"93.5"	"64.0"	"73.8"	"78.8"	"100.9"	"3.5"	"1458.2"	"1463.6"	"4648.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94842"	"TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1"	"0.000"	""	"13"	"7"	"12"	"7"	"621"	"66.2"	"5.06"	"2009.31"	"27.07"	"5"	"7"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505"	"9878"	"ENSG00000092203"	"TOX4"	"B4DPY8; B4DSM0; E7EV69; hsa:9878; O94842"	""	""	"0"	"0"	"169.9"	"114.9"	"159.9"	"152.1"	"133.8"	"102.7"	"234.2"	"7.1"	"2279.4"	"2246.5"	"5577.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2E9"	"Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5"	"0.000"	""	"10"	"13"	"20"	"12"	"1410"	"152.4"	"8.60"	"4274.41"	"27.03"	"11"	"9"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;translational apparatus"	"other molecular function"	"Pf05104"	"6238"	"ENSG00000125844"	"RRBP1"	"A0A0A0MRV0; A2A2S6; A6NCN6; hsa:6238; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476; Q9P2E9"	"Signaling by ALK fusions and activated point mutants"	"Ectoderm differentiation"	"2"	"0"	"561.3"	"495.2"	"594.7"	"558.7"	"502.5"	"592.9"	"1275.4"	"12.4"	"5022.6"	"5067.3"	"9181.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33176"	"Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1"	"0.000"	""	"11"	"9"	"14"	"9"	"963"	"109.6"	"6.51"	"1721.72"	"26.96"	"5"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3799"	"ENSG00000170759"	"KIF5B"	"A0AVB2; hsa:3799; P33176; Q5VZ85"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Insulin processing; Nuclear events stimulated by ALK signaling in cancer; RHO GTPases activate KTN1"	"Alzheimer's disease and miRNA effects; Envelope proteins and their potential roles in EDMD physiopathology; Insulin signaling; CCL18 signaling pathway; Alzheimer's disease"	"12"	"0"	"214.2"	"136.1"	"291.9"	"266.2"	"226.8"	"208.1"	"409.4"	"9.7"	"4119.4"	"3929.2"	"7550.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49757"	"Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2"	"0.000"	""	"12"	"6"	"10"	"6"	"651"	"70.8"	"8.51"	"1300.24"	"26.94"	"2"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00640, Pf06311"	"8650"	"ENSG00000133961"	"NUMB"	"B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; hsa:8650; P49757; Q6NUQ7; Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4"	"Recycling pathway of L1; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus"	"Notch signaling; VEGFA-VEGFR2 signaling; Head and neck squamous cell carcinoma; Neurogenesis regulation in the olfactory epithelium; TROP2 regulatory signaling; Notch signaling pathway"	"10"	"0"	"44.4"	"31.5"	"58.7"	"59.5"	"44.6"	"58.9"	"174.6"	"0.8"	"1800.7"	"1732.6"	"2746.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00139"	"Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3"	"0.000"	""	"13"	"8"	"15"	"7"	"706"	"79.9"	"6.68"	"2712.00"	"26.86"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3796"	"ENSG00000068796"	"KIF2A"	"A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; hsa:3796; O00139; Q7Z5I3; Q8N5Q7"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"9"	"1"	"135.7"	"104.8"	"158.9"	"137.1"	"144.7"	"130.6"	"330.4"	"19.5"	"2200.6"	"2163.7"	"4938.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12996"	"Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1"	"0.000"	""	"17"	"8"	"15"	"8"	"717"	"82.9"	"8.12"	"3658.66"	"26.84"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf05843"	"1479"	"ENSG00000176102"	"CSTF3"	"A8K471; D3DR04; E9PB40; hsa:1479; Q12996; Q32P22; Q96FQ8; Q96QD6; Q96QK4"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"81.7"	"78.2"	"96.3"	"82.7"	"90.6"	"86.3"	"190.2"	"11.9"	"2151.9"	"2308.7"	"4268.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43768"	"Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1"	"0.000"	""	"53"	"6"	"13"	"6"	"121"	"13.4"	"7.24"	"2332.17"	"26.77"	"5"	"6"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"2029"	"ENSG00000143420"	"ENSA"	"A8K1Z9; E9PB69; hsa:2029; O43768; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2; Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0"	"MASTL Facilitates Mitotic Progression"	""	"1"	"0"	"231.6"	"197.3"	"219.6"	"219.8"	"217.9"	"249.3"	"345.4"	"3.4"	"5270.7"	"5319.8"	"8666.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6WCQ1"	"Myosin phosphatase Rho-interacting protein OS=Homo sapiens OX=9606 GN=MPRIP PE=1 SV=3"	"0.000"	""	"8"	"6"	"14"	"6"	"1025"	"116.5"	"6.21"	"2845.07"	"26.75"	"4"	"6"	""	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00169"	"23164"	"ENSG00000133030"	"MPRIP"	"hsa:23164; Q3KQZ5; Q5FB94; Q6DHW2; Q6WCQ1; Q7Z5Y2; Q8N390; Q96G40"	"Signaling by BRAF and RAF1 fusions"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"2"	"0"	"35.1"	"29.4"	"33.2"	"34.6"	"33.7"	"39.1"	"83.4"	"8.8"	"449.2"	"399.3"	"847.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00267"	"Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1"	"0.000"	""	"10"	"8"	"12"	"8"	"1087"	"120.9"	"5.06"	"2280.15"	"26.64"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf03439, Pf11942"	"6829"	"ENSG00000196235"	"SUPT5H"	"hsa:6829; O00267; O43279; Q59G52; Q99639"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"Initiation of transcription and translation elongation at the HIV-1 LTR; mRNA processing"	"20"	"0"	"469.0"	"412.9"	"428.6"	"385.3"	"409.1"	"417.8"	"635.8"	"7.2"	"1964.3"	"1935.0"	"3250.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P016"	"Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1"	"0.000"	""	"40"	"9"	"15"	"9"	"225"	"25.7"	"9.25"	"2214.81"	"26.63"	"6"	"9"	""	""	""	"Pf01878"	"29087"	"ENSG00000151500"	"THYN1"	"hsa:29087; Q567Q2; Q9H3L4; Q9HC20; Q9P016"	""	""	"0"	"0"	"372.0"	"288.5"	"417.5"	"382.9"	"349.9"	"389.1"	"718.8"	"14.2"	"3666.4"	"3440.5"	"7599.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWS0"	"PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1"	"0.000"	""	"26"	"8"	"13"	"8"	"365"	"41.3"	"8.68"	"1597.37"	"26.50"	"5"	"8"	"developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf13771"	"84295"	"ENSG00000156531"	"PHF6"	"A8K230; B4E0G4; D3DTG3; E9PC97; hsa:84295; Q5JRC7; Q5JRC8; Q8IWS0; Q96JK3; Q9BRU0"	""	"Mesodermal commitment pathway"	"1"	"0"	"82.7"	"67.9"	"79.7"	"79.1"	"69.3"	"72.0"	"185.1"	"4.9"	"2129.2"	"2134.6"	"3899.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T37"	"RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2"	"0.000"	""	"8"	"6"	"13"	"5"	"977"	"107.1"	"10.08"	"2638.39"	"26.47"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"64783"	"ENSG00000162775"	"RBM15"	"A1A693; hsa:64783; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T37; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0"	""	""	"0"	"1"	"162.9"	"106.4"	"141.7"	"146.5"	"138.0"	"163.1"	"347.0"	"4.0"	"2007.0"	"1818.3"	"3954.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92738"	"USP6 N-terminal-like protein OS=Homo sapiens OX=9606 GN=USP6NL PE=1 SV=3"	"0.000"	""	"12"	"7"	"12"	"7"	"828"	"94.0"	"9.07"	"1933.64"	"26.42"	"5"	"6"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"9712"	"ENSG00000148429"	"USP6NL"	"A8KA79; hsa:9712; Q15400; Q5VV10; Q7L0K9; Q92738"	"Retrograde transport at the Trans-Golgi-Network"	"EGF/EGFR signaling pathway"	"2"	"0"	"60.7"	"42.8"	"68.1"	"71.9"	"92.3"	"162.2"	"506.4"	"8.8"	"2280.6"	"2181.0"	"2996.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VM9"	"Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2"	"0.000"	""	"9"	"9"	"16"	"9"	"953"	"106.3"	"8.32"	"2564.13"	"26.40"	"8"	"8"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18044"	"124245"	"ENSG00000158545"	"ZC3H18"	"hsa:124245; Q86VM9; Q96DG4; Q96MP7"	""	""	"0"	"0"	"534.3"	"392.1"	"455.6"	"483.1"	"378.5"	"464.6"	"2010.7"	"1.7"	"4069.3"	"4045.9"	"6709.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14936"	"Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3"	"0.000"	""	"9"	"8"	"13"	"8"	"926"	"105.1"	"6.43"	"2358.27"	"26.38"	"6"	"7"	"cell adhesion;protein metabolism;other metabolic processes;transport;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00595, Pf00625, Pf02828"	"8573"	"ENSG00000147044"	"CASK"	"A6NES1; B7ZKY0; hsa:8573; O14936; O43215; Q17RI4; Q59HA0; Q5VT16; Q5VT17; Q5VT18; Q5VT19; Q66T42; Q9BYH6; Q9NYB2; Q9NYB3"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Assembly and cell surface presentation of NMDA receptors; Nephrin family interactions; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle; Syndecan interactions"	"Parkin-ubiquitin proteasomal system pathway; Splicing factor NOVA regulated synaptic proteins"	"9"	"0"	"150.8"	"109.5"	"204.5"	"155.4"	"153.9"	"147.1"	"310.6"	"8.9"	"3087.6"	"3049.5"	"5639.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16629"	"Serine/arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1"	"0.000"	""	"30"	"5"	"13"	"5"	"238"	"27.4"	"11.82"	"1218.60"	"26.38"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6432"	"ENSG00000115875"	"SRSF7"	"B4DLU6; G5E9M3; hsa:6432; Q16629; Q564D3"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Minor Pathway"	"mRNA processing"	"7"	"0"	"210.3"	"191.1"	"174.9"	"180.6"	"160.5"	"187.1"	"480.3"	"2.3"	"1497.6"	"1453.3"	"2594.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49750"	"YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4"	"0.000"	""	"5"	"9"	"15"	"8"	"2146"	"241.5"	"6.55"	"2263.55"	"26.34"	"7"	"8"	"other biological processes"	"cytosol;nucleus"	""	"Pf13671"	"56252"	"ENSG00000119596"	"YLPM1"	"hsa:56252; P49750; P49752; Q96I64; Q9P1V7"	""	""	"0"	"1"	"495.9"	"335.5"	"425.7"	"452.0"	"390.4"	"421.9"	"870.2"	"9.5"	"3091.2"	"3191.6"	"5228.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08621"	"U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2"	"0.000"	""	"17"	"7"	"17"	"7"	"437"	"51.5"	"9.94"	"2805.21"	"26.29"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf12220"	"6625"	"ENSG00000104852"	"SNRNP70"	"B3KUA3; hsa:6625; P08621; P78493; P78494; Q15364; Q15686; Q15687; Q15689; Q99377; Q9UE45; Q9UE46; Q9UE47; Q9UE48; Q9UFQ6"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"475.7"	"333.5"	"392.9"	"356.9"	"375.3"	"373.7"	"549.9"	"3.5"	"1739.0"	"1681.5"	"3311.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13618"	"Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2"	"0.000"	""	"10"	"7"	"11"	"7"	"768"	"88.9"	"8.48"	"1561.85"	"26.25"	"4"	"7"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00888, Pf10557"	"8452"	"ENSG00000036257"	"CUL3"	"A8K536; B8ZZC3; hsa:8452; O75415; Q13618; Q569L3; Q9UBI8; Q9UET7"	"Potential therapeutics for SARS; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of DVL; Hedgehog 'on' state; Regulation of RAS by GAPs; Neddylation; KEAP1-NFE2L2 pathway; RHOBTB3 ATPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"Hedgehog signaling pathway; NRF2-ARE regulation; 22q11.2 copy number variation syndrome; Head and neck squamous cell carcinoma; 1p36 copy number variation syndrome"	"15"	"0"	"164.2"	"129.9"	"173.7"	"144.9"	"163.2"	"142.4"	"265.6"	"5.9"	"3311.0"	"3382.1"	"8072.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00610"	"Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5"	"0.000"	""	"4"	"7"	"16"	"7"	"1675"	"191.5"	"5.69"	"2961.78"	"26.23"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00637, Pf01394, Pf09268, Pf13838"	"1213"	"ENSG00000141367"	"CLTC"	"D3DU00; hsa:1213; Q00610; Q6N0A0; Q86TF2"	"ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; Recycling pathway of L1; MHC class II antigen presentation; RHOV GTPase cycle; Lysosome Vesicle Biogenesis; RHOU GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; Fragile X syndrome; 7q11.23 copy number variation syndrome; Complement and coagulation cascades"	"25"	"0"	"356.6"	"393.0"	"371.5"	"338.6"	"302.3"	"333.7"	"774.9"	"6.0"	"2785.8"	"2636.3"	"4539.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62241"	"40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2"	"0.000"	""	"27"	"6"	"13"	"6"	"208"	"24.2"	"10.32"	"1712.32"	"26.23"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01201"	"6202"	"ENSG00000142937"	"RPS8"	"hsa:6202; P09058; P62241; Q6IRL7"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"509.1"	"512.1"	"504.0"	"493.7"	"455.3"	"455.0"	"1660.3"	"13.1"	"3177.2"	"3380.1"	"4865.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17480"	"Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1"	"0.000"	""	"8"	"5"	"12"	"5"	"764"	"89.4"	"5.81"	"2459.20"	"26.21"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011, Pf14887"	"7343"	"ENSG00000108312"	"UBTF"	"A8K6R8; hsa:7343; P17480"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Opening"	"Ectoderm differentiation"	"6"	"0"	"62.2"	"42.9"	"103.4"	"88.8"	"81.2"	"77.9"	"220.7"	"1.0"	"1795.2"	"1761.2"	"3275.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75146"	"Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2"	"0.000"	""	"6"	"5"	"10"	"5"	"1068"	"119.3"	"6.67"	"1801.32"	"26.14"	"4"	"5"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"9026"	"ENSG00000130787"	"HIP1R"	"A6NHQ6; hsa:9026; O75146; Q6NXG8; Q9UED9"	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis"	"5q35 copy number variation"	"3"	"0"	"115.6"	"74.2"	"127.6"	"113.9"	"117.0"	"123.3"	"305.8"	"10.5"	"1490.0"	"1442.1"	"2669.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00535"	"Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3"	"0.000"	""	"33"	"9"	"14"	"9"	"292"	"33.3"	"7.66"	"2690.98"	"26.10"	"7"	"7"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1020"	"ENSG00000164885"	"CDK5"	"A1XKG3; hsa:1020; Q00535"	"DARPP-32 events; NPAS4 regulates expression of target genes; NGF-stimulated transcription; Regulation of TP53 Activity through Phosphorylation; Factors involved in megakaryocyte development and platelet production; CRMPs in Sema3A signaling; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Activated NTRK2 signals through CDK5"	"miRNA regulation of DNA damage response; Nicotine effect on dopaminergic neurons; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling in development and disease ; Alzheimer's disease; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"16"	"0"	"85.8"	"64.9"	"78.8"	"85.6"	"84.8"	"79.8"	"217.6"	"4.2"	"3524.7"	"3716.8"	"7532.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60832"	"H/ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3"	"0.000"	""	"12"	"6"	"11"	"6"	"514"	"57.6"	"9.42"	"2077.80"	"26.07"	"5"	"6"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01472, Pf01509, Pf08068, Pf16198"	"1736"	"ENSG00000130826"	"DKC1"	"F5BSB3; hsa:1736; O43845; O60832; Q96G67; Q9Y505"	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	""	"2"	"0"	"105.0"	"71.7"	"95.6"	"90.1"	"70.8"	"90.1"	"258.6"	"4.3"	"1913.3"	"2223.2"	"4331.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14126"	"Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2"	"0.000"	""	"7"	"6"	"12"	"6"	"1118"	"122.2"	"5.24"	"2647.78"	"26.06"	"6"	"6"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028"	"1829"	"ENSG00000046604"	"DSG2"	"hsa:1829; Q14126; Q4KKU6"	"Formation of the cornified envelope; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"Arrhythmogenic right ventricular cardiomyopathy; GDNF signaling"	"8"	"0"	"255.9"	"225.4"	"250.1"	"250.1"	"215.2"	"254.6"	"404.0"	"0.2"	"2645.5"	"2886.6"	"5055.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1F7"	"Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2"	"0.000"	""	"9"	"7"	"15"	"7"	"819"	"93.4"	"5.72"	"2432.93"	"26.04"	"6"	"7"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf04097"	"9688"	"ENSG00000102900"	"NUP93"	"B3KPQ8; hsa:9688; Q14705; Q8N1F7"	"Regulation of HSF1-mediated heat shock response; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"192.0"	"130.7"	"186.8"	"169.0"	"178.7"	"183.3"	"227.8"	"4.7"	"1624.0"	"1589.6"	"3168.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15511"	"Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3"	"0.000"	""	"38"	"4"	"12"	"3"	"151"	"16.3"	"5.67"	"2018.43"	"26.03"	"2"	"4"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04699"	"10092"	"ENSG00000162704"	"ARPC5"	"A6NEC4; hsa:10092; O15511; Q6PG42"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton"	"8"	"1"	"132.4"	"97.5"	"121.9"	"118.4"	"134.7"	"117.4"	"232.8"	"1.1"	"2068.2"	"2108.1"	"4471.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13769"	"THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2"	"0.000"	""	"17"	"8"	"13"	"8"	"683"	"78.5"	"6.87"	"2315.34"	"25.80"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09766"	"8563"	"ENSG00000100296"	"THOC5"	"hsa:8563; O60839; Q13769; Q9UPZ5"	"Signaling by CSF1 (M-CSF) in myeloid cells; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"4"	"0"	"83.2"	"67.5"	"87.5"	"84.8"	"84.4"	"72.4"	"254.4"	"8.4"	"1597.1"	"1627.8"	"2927.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29966"	"Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4"	"0.000"	""	"21"	"6"	"11"	"6"	"332"	"31.5"	"4.45"	"1738.63"	"25.77"	"4"	"6"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"4082"	"ENSG00000277443"	"MARCKS"	"E1P560; hsa:4082; P29966; Q2LA83; Q5TDB7"	"Acetylcholine regulates insulin secretion"	"Brain-derived neurotrophic factor (BDNF) signaling pathway"	"2"	"0"	"162.9"	"147.3"	"172.9"	"168.3"	"148.5"	"158.7"	"307.0"	"26.3"	"5007.9"	"5913.2"	"8603.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUP9"	"Protein lin-7 homolog C OS=Homo sapiens OX=9606 GN=LIN7C PE=1 SV=1"	"0.000"	""	"23"	"7"	"15"	"4"	"197"	"21.8"	"8.43"	"3061.44"	"25.74"	"7"	"6"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf02828"	"55327"	"ENSG00000148943"	"LIN7C"	"hsa:55327; Q9NUP9"	"Neurexins and neuroligins; Assembly and cell surface presentation of NMDA receptors; Dopamine Neurotransmitter Release Cycle"	""	"3"	"3"	"354.5"	"275.9"	"327.8"	"293.8"	"296.1"	"327.7"	"592.6"	"9.4"	"6468.8"	"6345.8"	"11496.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39687"	"Acidic leucine-rich nuclear phosphoprotein 32 family member A OS=Homo sapiens OX=9606 GN=ANP32A PE=1 SV=1"	"0.000"	""	"23"	"6"	"12"	"5"	"249"	"28.6"	"4.09"	"1561.39"	"25.71"	"5"	"5"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf14580"	"8125"	"ENSG00000140350"	"ANP32A"	"B2R6T4; hsa:8125; P39687; Q53FK4; Q5J8L8; Q7M4N6"	"HuR (ELAVL1) binds and stabilizes mRNA"	"IL-18 signaling pathway"	"2"	"1"	"318.8"	"345.6"	"393.5"	"331.4"	"325.2"	"299.1"	"1028.9"	"11.2"	"2984.9"	"3009.1"	"3965.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52907"	"F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3"	"0.000"	""	"26"	"4"	"9"	"4"	"286"	"32.9"	"5.69"	"1689.52"	"25.65"	"3"	"4"	"cell organization and biogenesis"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"829"	"ENSG00000116489"	"CAPZA1"	"hsa:829; P52907; Q53FQ6; Q6FHD5"	"Sensory processing of sound by inner hair cells of the cochlea; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	""	"8"	"0"	"33.3"	"12.8"	"38.3"	"35.1"	"35.4"	"35.2"	"86.5"	"2.6"	"745.8"	"736.6"	"1335.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33993"	"DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4"	"0.000"	""	"11"	"6"	"11"	"6"	"719"	"81.3"	"6.46"	"1954.07"	"25.55"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4176"	"ENSG00000166508"	"MCM7"	"A4D2A1; A4D2A2; E9PGN9; hsa:4176; P33993; Q15076; Q96D34; Q96GL1"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"12"	"0"	"169.3"	"113.0"	"152.7"	"159.8"	"143.7"	"146.9"	"225.6"	"0.7"	"1525.6"	"1590.3"	"4294.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75794"	"Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1"	"0.000"	""	"19"	"6"	"16"	"6"	"336"	"39.1"	"4.81"	"2676.70"	"25.54"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf07065"	"8872"	"ENSG00000151465"	"CDC123"	"A8JZZ7; hsa:8872; O75794; Q14107; Q5T0L4; Q5T0L5; Q5T0L7; Q5T0L8; Q5T0L9"	""	""	"0"	"0"	"51.8"	"25.6"	"83.3"	"57.2"	"59.8"	"41.7"	"89.4"	"10.6"	"3967.3"	"4014.4"	"6180.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6N069"	"N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA16 PE=1 SV=2"	"0.000"	""	"8"	"7"	"14"	"2"	"864"	"101.4"	"7.87"	"2044.81"	"25.52"	"5"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf07719, Pf12569"	"79612"	"ENSG00000172766"	"NAA16"	"B0QZ59; hsa:79612; Q5VSP9; Q6N069; Q6P2D5; Q8N5J3; Q8N870"	""	""	"0"	"0"	"19.4"	"13.8"	"20.0"	"19.4"	"26.0"	"21.8"	"40.4"	"0.0"	"647.0"	"633.7"	"1241.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04837"	"Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1"	"0.000"	""	"37"	"4"	"12"	"4"	"148"	"17.2"	"9.60"	"2297.78"	"25.47"	"4"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00436"	"6742"	"ENSG00000106028; ENSG00000262771"	"SSBP1"	"hsa:6742; Q04837"	"Transcriptional activation of mitochondrial biogenesis"	""	"1"	"0"	"260.7"	"207.4"	"231.9"	"202.8"	"219.2"	"253.3"	"474.9"	"3.3"	"1789.0"	"1699.1"	"2976.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35269"	"General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2"	"0.000"	""	"17"	"8"	"13"	"8"	"517"	"58.2"	"7.49"	"2908.34"	"25.39"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf05793"	"2962"	"ENSG00000125651"	"GTF2F1"	"B2RCS0; hsa:2962; P35269; Q9BWN0"	"Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	""	"32"	"0"	"76.7"	"64.6"	"85.6"	"84.3"	"69.1"	"87.6"	"184.0"	"5.8"	"1106.7"	"1087.6"	"2509.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2A7"	"Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1"	"0.000"	""	"8"	"7"	"12"	"7"	"1128"	"128.7"	"6.62"	"2034.11"	"25.35"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf09735"	"10787"	"ENSG00000061676"	"NCKAP1"	"hsa:10787; O60329; Q53QN5; Q53S94; Q53Y35; Q9Y2A7"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"Exercise-induced circadian regulation; Regulation of actin cytoskeleton"	"9"	"0"	"165.9"	"131.6"	"213.0"	"166.1"	"175.9"	"160.1"	"317.9"	"8.6"	"2244.7"	"2266.4"	"4837.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41567"	"Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1"	"0.000"	""	"25"	"3"	"12"	"1"	"113"	"12.7"	"7.44"	"2597.65"	"25.31"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10209"	"ENSG00000173812"	"EIF1"	"hsa:10209; P41567; Q9UNQ9"	""	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"2"	"0"	"22.4"	"11.0"	"46.7"	"42.8"	"41.6"	"22.8"	"101.9"	"1.2"	"1522.7"	"1346.8"	"3134.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13185"	"Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4"	"0.000"	""	"33"	"5"	"11"	"4"	"183"	"20.8"	"5.33"	"2131.07"	"25.29"	"3"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"11335"	"ENSG00000122565"	"CBX3"	"hsa:11335; Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6"	"RNA Polymerase I Promoter Escape; Transcriptional Regulation by E2F6; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"	"Exercise-induced circadian regulation; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"6"	"0"	"119.2"	"80.8"	"150.0"	"129.3"	"120.1"	"119.3"	"205.4"	"0.9"	"1176.7"	"1260.0"	"3884.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49407"	"Beta-arrestin-1 OS=Homo sapiens OX=9606 GN=ARRB1 PE=1 SV=2"	"0.000"	""	"20"	"6"	"14"	"6"	"418"	"47.0"	"6.20"	"2626.51"	"25.28"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00339, Pf02752"	"408"	"ENSG00000137486"	"ARRB1"	"B6V9G8; hsa:408; O75625; O75630; P49407; Q2PP20; Q9BTK8"	"Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Cargo recognition for clathrin-mediated endocytosis; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"25"	"0"	"25.2"	"20.0"	"37.2"	"23.6"	"33.0"	"48.5"	"105.6"	"3.4"	"988.8"	"957.5"	"1623.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6L8Q7"	"2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2"	"0.000"	""	"14"	"7"	"11"	"7"	"609"	"67.3"	"6.57"	"1392.68"	"25.24"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03372"	"201626"	"ENSG00000174840"	"PDE12"	"B4DTU8; hsa:201626; Q6L8Q7; Q8IYU3; Q8NDU2; Q8TE78"	"OAS antiviral response"	"Phosphodiesterases in neuronal function"	"2"	"0"	"151.2"	"104.8"	"150.4"	"132.5"	"145.8"	"129.8"	"242.3"	"11.7"	"2117.6"	"2129.3"	"4712.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98179"	"RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1"	"0.000"	""	"39"	"5"	"14"	"5"	"157"	"17.2"	"8.91"	"2103.61"	"25.15"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity"	"Pf00076"	"5935"	"ENSG00000102317"	"RBM3"	"hsa:5935; P98179"	""	""	"0"	"0"	"197.0"	"325.7"	"106.7"	"138.7"	"118.3"	"172.1"	"621.2"	"3.4"	"1179.8"	"1225.0"	"1614.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNE7"	"E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2"	"0.000"	""	"27"	"6"	"12"	"6"	"303"	"34.8"	"5.87"	"2285.65"	"25.15"	"5"	"5"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf04564, Pf12895, Pf18391"	"10273"	"ENSG00000103266"	"STUB1"	"A2IDB9; hsa:10273; O60526; Q969U2; Q9HBT1; Q9UNE7"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Regulation of TNFR1 signaling; Downregulation of TGF-beta receptor signaling"	"Androgen receptor signaling pathway; Parkin-ubiquitin proteasomal system pathway"	"10"	"0"	"90.5"	"78.0"	"82.7"	"62.7"	"82.8"	"82.4"	"225.3"	"6.4"	"1379.1"	"1363.5"	"2619.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2U2"	"Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2"	"0.000"	""	"23"	"5"	"9"	"5"	"334"	"37.9"	"7.39"	"1557.01"	"25.12"	"3"	"5"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00719"	"27068"	"ENSG00000138777"	"PPA2"	"B4DLP7; F8WDN9; hsa:27068; I6L9B6; Q4W5E9; Q6PG51; Q8TBW0; Q96E55; Q9H0T0; Q9H2U2; Q9NX37; Q9P033; Q9ULX0"	"Mitochondrial tRNA aminoacylation; Pyrophosphate hydrolysis"	""	"2"	"0"	"40.2"	"34.4"	"54.0"	"40.4"	"42.0"	"39.2"	"80.7"	"3.5"	"1743.4"	"2020.9"	"5016.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BP3"	"Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=PPWD1 PE=1 SV=1"	"0.000"	""	"12"	"6"	"12"	"6"	"646"	"73.5"	"7.15"	"2344.35"	"25.11"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160, Pf00400"	"23398"	"ENSG00000113593"	"PPWD1"	"B4DWR9; hsa:23398; Q15002; Q7KZ89; Q96BP3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"92.9"	"85.4"	"101.1"	"94.3"	"95.4"	"96.6"	"204.3"	"1.4"	"2794.9"	"2768.7"	"5027.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N488"	"RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2"	"0.000"	""	"39"	"6"	"9"	"6"	"228"	"24.8"	"9.63"	"805.55"	"25.10"	"2"	"6"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf17219"	"23429"	"ENSG00000163602; ENSG00000281766"	"RYBP"	"hsa:23429; Q8N488; Q9P2W5; Q9UMW4"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Transcriptional Regulation by E2F6"	""	"2"	"0"	"412.3"	"267.0"	"408.5"	"388.1"	"335.6"	"295.1"	"405.7"	"1.3"	"1996.2"	"1839.5"	"4161.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12788"	"Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2"	"0.000"	""	"12"	"5"	"12"	"5"	"808"	"89.0"	"6.90"	"1781.02"	"25.05"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf08625"	"10607"	"ENSG00000183751"	"TBL3"	"hsa:10607; Q12788; Q59GD6; Q8IVB7; Q96A78"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"111.2"	"82.8"	"130.7"	"112.1"	"126.3"	"114.2"	"189.3"	"2.6"	"1851.5"	"1916.6"	"3517.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92900"	"Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2"	"0.000"	""	"7"	"6"	"11"	"6"	"1129"	"124.3"	"6.61"	"2460.17"	"25.02"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09416, Pf13086, Pf13087, Pf18141"	"5976"	"ENSG00000005007"	"UPF1"	"hsa:5976; O00239; O43343; Q86Z25; Q92842; Q92900"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Pathophysiological roles of DUX4 in FSHD1"	"3"	"0"	"78.0"	"50.0"	"81.1"	"83.5"	"79.3"	"81.8"	"192.2"	"0.9"	"1300.2"	"1256.4"	"2536.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60610"	"Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2"	"0.000"	""	"7"	"5"	"8"	"5"	"1272"	"141.3"	"5.41"	"1288.12"	"25.02"	"3"	"5"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02181, Pf06346, Pf06367, Pf06371"	"1729"	"ENSG00000131504"	"DIAPH1"	"A6NF18; B7ZKW2; E9PEZ2; hsa:1729; O60610; Q17RN4; Q59FH8; Q9UC76"	"RHOC GTPase cycle; RHOA GTPase cycle; RHO GTPases Activate Formins; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; ERBB2 Regulates Cell Motility"	"Microtubule cytoskeleton regulation; AGE/RAGE pathway; Focal adhesion; Type 2 papillary renal cell carcinoma; Regulation of actin cytoskeleton; G13 signaling pathway"	"14"	"0"	"103.3"	"47.9"	"101.3"	"102.4"	"97.9"	"75.8"	"79.7"	"1.4"	"480.0"	"508.7"	"1004.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26599"	"Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1"	"0.000"	""	"18"	"7"	"14"	"6"	"531"	"57.2"	"9.17"	"2765.13"	"25.01"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"749887"	"ENSPPYG00000009289; ENSPTRG00000010165"	"PTBP1"	"A0A2J8IKP3; A0A2J8RA51; A0A6D2WFY9; A0A8I5YPF9; K7AXA8"	""	""	"0"	"2"	"610.6"	"472.4"	"726.5"	"566.2"	"645.3"	"587.2"	"1206.3"	"1.6"	"4511.4"	"4644.9"	"8829.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULV4"	"Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1"	"0.000"	""	"23"	"11"	"19"	"11"	"474"	"53.2"	"7.08"	"3983.81"	"24.99"	"10"	"8"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"23603"	"ENSG00000110880"	"CORO1C"	"A7MAP0; A7MAP1; B3KU12; hsa:23603; Q9NSK5; Q9ULV4"	""	""	"0"	"0"	"1010.4"	"749.1"	"781.9"	"864.3"	"919.9"	"699.4"	"1241.2"	"2.8"	"6025.3"	"6198.0"	"12111.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35908"	"Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2"	"0.000"	""	"15"	"9"	"17"	"6"	"639"	"65.4"	"8.00"	"3172.92"	"24.89"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3849"	"ENSG00000172867"	"KRT2"	"hsa:3849; P35908; Q4VAQ2"	"Formation of the cornified envelope"	""	"2"	"2"	"563.9"	"1044.7"	"269.5"	"1596.6"	"296.9"	"2591.1"	"1357.7"	"0.7"	"1971.4"	"2096.9"	"2231.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH65"	"Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70 PE=1 SV=1"	"0.000"	""	"16"	"9"	"14"	"9"	"585"	"69.0"	"5.87"	"2524.89"	"24.82"	"7"	"7"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00169"	"23075"	"ENSG00000133789"	"SWAP70"	"D3DQV1; hsa:23075; O75135; Q7LCY6; Q9P061; Q9P0Z8; Q9UH65"	"RAC1 GTPase cycle; RAC3 GTPase cycle; RAC2 GTPase cycle"	""	"3"	"0"	"96.5"	"79.0"	"122.3"	"101.5"	"100.9"	"125.3"	"263.5"	"6.1"	"3395.6"	"3544.7"	"6314.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDN6"	"Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2"	"0.000"	""	"12"	"4"	"13"	"4"	"353"	"41.4"	"9.92"	"2123.72"	"24.73"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"55299"	"ENSG00000113460"	"BRIX1"	"A8K0P5; hsa:55299; Q3ZTT4; Q8N453; Q8TDN6; Q96DH1"	""	"Gastric cancer network 2"	"1"	"0"	"107.9"	"95.8"	"135.2"	"110.9"	"103.6"	"107.5"	"551.3"	"5.4"	"2066.7"	"2067.9"	"3629.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13642"	"Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4"	"0.000"	""	"22"	"6"	"10"	"6"	"323"	"36.2"	"8.97"	"1556.16"	"24.72"	"4"	"6"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"2273"	"ENSG00000022267"	"FHL1"	"B7Z5T4; B7Z793; hsa:2273; O95212; Q13230; Q13642; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630"	""	"Notch signaling pathway"	"1"	"0"	"244.9"	"216.4"	"235.6"	"255.6"	"217.2"	"140.7"	"367.9"	"11.9"	"1853.4"	"1935.3"	"3069.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14160"	"Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4"	"0.000"	""	"6"	"8"	"13"	"7"	"1630"	"174.8"	"5.07"	"2021.27"	"24.72"	"6"	"7"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"173.5"	"118.5"	"187.0"	"164.5"	"161.3"	"167.1"	"241.1"	"5.7"	"1271.8"	"1309.9"	"2960.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TV6"	"Tetratricopeptide repeat protein 7B OS=Homo sapiens OX=9606 GN=TTC7B PE=1 SV=3"	"0.000"	""	"8"	"6"	"12"	"6"	"843"	"94.1"	"6.89"	"1686.45"	"24.72"	"5"	"6"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	"Pf12895, Pf13181, Pf13424, Pf19440"	"145567"	"ENSG00000165914"	"TTC7B"	"hsa:145567; Q86TV6; Q86U24; Q86VT3"	""	""	"0"	"0"	"89.2"	"71.9"	"121.4"	"111.1"	"93.4"	"83.3"	"208.3"	"10.4"	"1698.5"	"1695.0"	"3386.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43172"	"U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2"	"0.000"	""	"15"	"5"	"9"	"5"	"522"	"58.4"	"7.42"	"1858.20"	"24.68"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08799"	"9128"	"ENSG00000136875"	"PRPF4"	"hsa:9128; O43172; O43445; O43864; Q5T1M8; Q96DG2; Q96IK4"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"99.1"	"66.2"	"90.2"	"93.9"	"96.9"	"80.0"	"146.6"	"3.3"	"965.2"	"923.8"	"2175.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96F07"	"Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens OX=9606 GN=CYFIP2 PE=1 SV=2"	"0.000"	""	"6"	"7"	"15"	"1"	"1278"	"148.3"	"7.31"	"2367.79"	"24.67"	"7"	"7"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05994, Pf07159"	"26999"	"ENSG00000055163"	"CYFIP2"	"A6NLT2; D3DQJ3; hsa:26999; Q53EN5; Q96F07; Q9NTK4; Q9ULQ2; Q9UN29"	"RAC1 GTPase cycle; VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	"Fragile X syndrome; Regulation of actin cytoskeleton"	"7"	"0"	"25.8"	"25.0"	"19.9"	"27.5"	"24.7"	"25.2"	"34.1"	"0.0"	"172.3"	"171.8"	"313.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99633"	"Pre-mRNA-splicing factor 18 OS=Homo sapiens OX=9606 GN=PRPF18 PE=1 SV=1"	"0.000"	""	"24"	"7"	"11"	"7"	"342"	"39.8"	"8.15"	"1996.76"	"24.64"	"5"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02840, Pf08799"	"8559"	"ENSG00000165630"	"PRPF18"	"hsa:8559; Q5T9P9; Q99633; Q9BUI9"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"51.1"	"24.9"	"65.7"	"55.6"	"52.5"	"57.7"	"166.9"	"9.2"	"1823.0"	"1707.3"	"2974.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12797"	"Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3"	"0.000"	""	"10"	"6"	"11"	"6"	"758"	"85.8"	"5.01"	"2526.81"	"24.56"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf05118, Pf05279, Pf13432"	"444"	"ENSG00000198363"	"ASPH"	"A0A0A0MSK8; A6NDF4; A6NHI2; B4DIC9; B4E2K4; B7ZM95; E5RGP5; F5H667; hsa:444; Q12797; Q6NXR7; Q8TB28; Q9H291; Q9H2C4; Q9NRI0; Q9NRI1; Q9Y4J0"	"Stimuli-sensing channels; Ion homeostasis"	""	"2"	"0"	"73.5"	"44.9"	"62.8"	"64.0"	"57.5"	"65.0"	"128.7"	"0.0"	"2485.4"	"2754.0"	"5787.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EK6"	"Glucosamine 6-phosphate N-acetyltransferase OS=Homo sapiens OX=9606 GN=GNPNAT1 PE=1 SV=1"	"0.000"	""	"22"	"3"	"11"	"3"	"184"	"20.7"	"7.99"	"2246.61"	"24.54"	"1"	"3"	"other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00583"	"64841"	"ENSG00000100522"	"GNPNAT1"	"hsa:64841; Q96EK6"	"Synthesis of UDP-N-acetyl-glucosamine"	""	"1"	"0"	"260.7"	"210.1"	"270.3"	"264.7"	"230.3"	"247.2"	"360.4"	"3.6"	"1358.8"	"1310.6"	"2738.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19525"	"Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2"	"0.000"	""	"12"	"6"	"12"	"6"	"551"	"62.1"	"8.40"	"1835.75"	"24.54"	"4"	"6"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00035, Pf00069"	"5610"	"ENSG00000055332"	"EIF2AK2"	"A8K3P0; D6W584; E9PC80; hsa:5610; P19525; Q52M43; Q7Z6F6; Q9UIR4"	"ISG15 antiviral mechanism; Interferon alpha/beta signaling; Inhibition of PKR"	"Translation factors; Alzheimer's disease and miRNA effects; Ebola virus infection in host; Measles virus infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; Alzheimer's disease; Roles of ceramides in development of insulin resistance; Type II interferon signaling"	"12"	"0"	"79.0"	"58.1"	"104.9"	"79.6"	"102.2"	"93.9"	"208.0"	"10.9"	"2263.6"	"2107.4"	"5222.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3E1"	"Hepatoma-derived growth factor-related protein 3 OS=Homo sapiens OX=9606 GN=HDGFL3 PE=1 SV=1"	"0.000"	""	"40"	"7"	"11"	"7"	"203"	"22.6"	"7.99"	"1523.40"	"24.54"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00855"	"50810"	"ENSG00000166503"	"HDGFL3"	"hsa:50810; Q9Y3E1"	""	""	"0"	"0"	"247.9"	"149.8"	"212.3"	"236.1"	"190.8"	"188.7"	"271.5"	"1.7"	"3924.8"	"3718.1"	"8873.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NSI4"	"RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2"	"0.000"	""	"9"	"5"	"10"	"5"	"855"	"97.5"	"8.41"	"1965.91"	"24.52"	"4"	"5"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf17659"	"55086"	"ENSG00000147231"	"RADX"	"H7BY89; hsa:55086; Q4G0L7; Q5JQS1; Q5JRF9; Q6NSI4; Q6PHY5; Q6PII9; Q6PJU8; Q9H7W5; Q9NWA6"	""	""	"0"	"0"	"88.3"	"95.6"	"94.4"	"86.8"	"84.2"	"96.5"	"297.9"	"2.9"	"1284.7"	"1290.4"	"2694.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09661"	"U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2"	"0.000"	""	"36"	"8"	"16"	"8"	"255"	"28.4"	"8.62"	"2683.15"	"24.44"	"8"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf14580"	"6627"	"ENSG00000131876"	"SNRPA1"	"B2R5I6; hsa:6627; P09661; Q8TBD2"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"mRNA processing"	"3"	"0"	"460.9"	"432.1"	"377.6"	"396.1"	"355.2"	"382.0"	"1029.7"	"0.3"	"2669.4"	"2977.0"	"6346.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX01"	"SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2"	"0.000"	""	"9"	"7"	"13"	"7"	"1082"	"120.1"	"7.28"	"2228.12"	"24.38"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"10147"	"ENSG00000064607"	"SUGP2"	"C9JI71; hsa:10147; O15071; O60369; Q5JPH7; Q8IX01; Q8WUF7"	""	"mRNA processing"	"1"	"0"	"164.4"	"138.5"	"171.9"	"161.4"	"162.2"	"149.2"	"266.3"	"3.3"	"872.0"	"943.9"	"1801.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41250"	"Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3"	"0.000"	""	"14"	"6"	"7"	"6"	"739"	"83.1"	"7.03"	"241.36"	"24.32"	"1"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"non-structural extracellular;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf00587, Pf03129"	"2617"	"ENSG00000106105"	"GARS1"	"A0A090N8G0; B3KQA2; B4DIA0; hsa:2617; P41250; Q969Y1"	"Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	""	"2"	"0"	"47.3"	"37.6"	"45.5"	"47.1"	"52.1"	"54.6"	"76.1"	"2.9"	"874.6"	"886.3"	"2792.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y224"	"RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1"	"0.000"	""	"21"	"4"	"12"	"4"	"244"	"28.1"	"6.65"	"2591.92"	"24.26"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10036"	"51637"	"ENSG00000087302"	"RTRAF"	"hsa:51637; Q9Y224"	"tRNA processing in the nucleus"	""	"1"	"0"	"135.9"	"105.2"	"162.4"	"125.4"	"145.5"	"127.5"	"307.7"	"8.4"	"1353.4"	"1333.3"	"2679.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61160"	"Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1"	"0.000"	""	"22"	"8"	"17"	"8"	"394"	"44.7"	"6.74"	"3315.66"	"24.24"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10097"	"ENSG00000138071"	"ACTR2"	"B2RCP5; D6W5F4; E9PF41; hsa:10097; O15142; P61160; Q96C82"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; EPHB-mediated forward signaling"	"Physico-chemical features and toxicity-associated pathways; Embryonic stem cell pluripotency pathways"	"8"	"0"	"219.1"	"170.0"	"251.2"	"211.1"	"247.7"	"229.2"	"399.1"	"1.1"	"4411.6"	"4943.7"	"8293.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75390"	"Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2"	"0.000"	""	"14"	"7"	"16"	"7"	"466"	"51.7"	"8.32"	"2752.43"	"24.21"	"7"	"7"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00285"	"1431"	"ENSG00000062485"	"CS"	"hsa:1431; O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"6"	"0"	"689.2"	"630.4"	"669.8"	"654.2"	"598.9"	"574.3"	"846.0"	"1.7"	"2003.0"	"2176.9"	"4259.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04843"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1"	"0.000"	""	"15"	"6"	"10"	"6"	"607"	"68.5"	"6.38"	"1695.91"	"24.15"	"4"	"6"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf04597"	"6184"	"ENSG00000163902"	"RPN1"	"B2R5Z0; D3DNB6; hsa:6184; P04843; Q68DT1"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"Proteasome degradation; N-glycan biosynthesis"	"5"	"0"	"34.3"	"31.5"	"48.1"	"44.4"	"38.2"	"46.8"	"91.3"	"3.0"	"951.0"	"1098.7"	"2239.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92614"	"Unconventional myosin-XVIIIa OS=Homo sapiens OX=9606 GN=MYO18A PE=1 SV=3"	"0.000"	""	"5"	"8"	"12"	"8"	"2054"	"233.0"	"6.30"	"3043.54"	"23.93"	"6"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf17820"	"399687"	"ENSG00000196535"	"MYO18A"	"hsa:399687; Q5H9U3; Q5QD01; Q5W9F9; Q5W9G1; Q8IXP8; Q92614"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	""	"3"	"0"	"32.8"	"25.0"	"50.7"	"40.6"	"39.5"	"41.3"	"111.5"	"5.5"	"1210.8"	"1281.6"	"2577.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46939"	"Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2"	"0.000"	""	"2"	"5"	"12"	"5"	"3433"	"394.2"	"5.33"	"2828.67"	"23.75"	"5"	"5"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00569, Pf09068, Pf09069"	"7402"	"ENSG00000152818"	"UTRN"	"hsa:7402; P46939; Q5SYY1; Q5SZ57; Q9UJ40"	"EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"Primary focal segmental glomerulosclerosis (FSGS)"	"2"	"0"	"52.2"	"53.3"	"58.7"	"52.3"	"54.7"	"51.8"	"114.9"	"5.9"	"1173.3"	"1210.7"	"2478.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H501"	"ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1"	"0.000"	""	"7"	"4"	"8"	"4"	"851"	"98.7"	"5.11"	"1397.18"	"23.73"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08159"	"51575"	"ENSG00000089048"	"ESF1"	"hsa:51575; Q86X92; Q9H501; Q9H9Q5; Q9HA35; Q9NX93; Q9P1S6"	""	""	"0"	"0"	"121.0"	"92.9"	"115.6"	"123.6"	"103.1"	"97.6"	"280.9"	"7.4"	"1707.0"	"1606.6"	"3898.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55036"	"26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1"	"0.000"	""	"17"	"5"	"9"	"5"	"377"	"40.7"	"4.79"	"1342.51"	"23.65"	"3"	"5"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02809, Pf13519"	"5710"	"ENSG00000159352"	"PSMD4"	"D3DV16; hsa:5710; P55036; Q5VWC5; Q9NS92"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"64"	"0"	"70.4"	"48.8"	"74.1"	"76.5"	"85.0"	"75.9"	"120.5"	"7.0"	"1761.8"	"1645.9"	"4328.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00425"	"Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2"	"0.000"	""	"8"	"4"	"12"	"3"	"579"	"63.7"	"8.87"	"2216.97"	"23.52"	"4"	"4"	"protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10643"	"ENSG00000136231"	"IGF2BP3"	"A0A4Z5; hsa:10643; O00425; Q63HM0; Q6MZZ2; Q86VB1"	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	""	"1"	"1"	"134.3"	"109.2"	"167.6"	"159.9"	"159.4"	"142.3"	"320.8"	"6.6"	"1233.7"	"1204.4"	"2399.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GQ7"	"Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2"	"0.000"	""	"12"	"9"	"15"	"9"	"796"	"89.8"	"9.28"	"2305.10"	"23.51"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"55661"	""	"DDX27"	"A0AVB6; B7ZLY1; hsa:55661; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96GQ7; Q96L97; Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6"	""	""	"0"	"0"	"150.1"	"124.0"	"157.5"	"135.4"	"144.5"	"147.1"	"494.4"	"3.8"	"1474.2"	"1507.4"	"2883.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75528"	"Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1"	"0.000"	""	"10"	"2"	"5"	"2"	"432"	"48.9"	"6.27"	"589.48"	"23.50"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf10198"	"10474"	"ENSG00000171148"	"TADA3"	"hsa:10474; O75528; Q6FI83; Q9UFS2"	"Ub-specific processing proteases; Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	""	"3"	"0"	"44.4"	"30.3"	"34.9"	"43.1"	"41.2"	"39.3"	"74.3"	"4.1"	"640.3"	"613.0"	"1293.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB4"	"SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2"	"0.000"	""	"11"	"5"	"11"	"5"	"655"	"74.3"	"6.16"	"1746.08"	"23.49"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"6732"	"ENSG00000096063"	"SRPK1"	"B4DS61; hsa:6732; Q12890; Q5R364; Q5R365; Q8IY12; Q96SB4"	"Maturation of nucleoprotein"	"VEGFA-VEGFR2 signaling; mRNA processing"	"3"	"0"	"115.0"	"72.5"	"142.6"	"122.2"	"121.0"	"129.2"	"289.3"	"8.1"	"1488.9"	"1423.3"	"3952.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14617"	"AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1"	"0.000"	""	"7"	"6"	"12"	"6"	"1153"	"130.1"	"8.48"	"1727.01"	"23.49"	"5"	"6"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01602, Pf06375"	"8943"	"ENSG00000065000"	"AP3D1"	"hsa:8943; O00202; O14617; O75262; Q59HF5; Q96G11; Q9H3C6"	""	""	"0"	"0"	"67.3"	"58.5"	"83.9"	"81.4"	"75.2"	"86.9"	"143.2"	"5.1"	"1441.5"	"1448.3"	"2465.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05204"	"Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3"	"0.000"	""	"40"	"5"	"15"	"5"	"90"	"9.4"	"9.99"	"2071.02"	"23.47"	"5"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3151"	"ENSG00000198830"	"HMGN2"	"hsa:3151; P05204; Q0VGD5; Q6FGI5; Q96C64"	""	""	"0"	"0"	"132.1"	"124.3"	"116.2"	"134.5"	"54.4"	"129.4"	"242.1"	"7.0"	"1747.4"	"1784.3"	"4781.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08752"	"Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3"	"0.000"	""	"22"	"8"	"13"	"7"	"370"	"40.7"	"7.21"	"2015.59"	"23.43"	"6"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160, Pf13176"	"5481"	"ENSG00000171497"	"PPID"	"B2R9V2; hsa:5481; Q08752"	"ESR-mediated signaling"	"Alzheimer's disease and miRNA effects; NO/cGMP/PKG mediated neuroprotection; Alzheimer's disease"	"4"	"0"	"77.2"	"53.1"	"73.5"	"78.2"	"88.4"	"76.6"	"137.7"	"2.0"	"2173.4"	"2220.6"	"4112.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15293"	"Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1"	"0.000"	""	"18"	"5"	"10"	"5"	"331"	"38.9"	"5.00"	"2103.80"	"23.43"	"3"	"5"	"developmental processes"	"ER/Golgi"	"other molecular function"	"Pf13202"	"5954"	"ENSG00000049449"	"RCN1"	"B7Z1M1; D3DR00; hsa:5954; Q15293"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"614.8"	"349.5"	"529.5"	"501.6"	"547.7"	"549.1"	"1204.2"	"1.4"	"2752.9"	"2585.5"	"4458.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75150"	"E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5"	"0.000"	""	"8"	"7"	"11"	"5"	"1001"	"113.6"	"6.29"	"1836.83"	"23.42"	"4"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"9810"	"ENSG00000103549"	"RNF40"	"A0A024QZG0; hsa:9810; O75150; Q6AHZ6; Q6N005; Q7L3T6; Q8N615; Q96T18; Q9BSV9; Q9HC82"	"E3 ubiquitin ligases ubiquitinate target proteins"	"ATM signaling in development and disease"	"2"	"0"	"250.3"	"170.7"	"226.5"	"197.9"	"183.1"	"227.2"	"393.6"	"1.6"	"2283.8"	"2254.5"	"3710.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKX7"	"Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2"	"0.000"	""	"13"	"5"	"9"	"5"	"468"	"50.1"	"7.06"	"1074.31"	"23.41"	"3"	"5"	"transport"	"other membranes;nucleus"	""	"Pf00638, Pf08911"	"10762"	"ENSG00000093000"	"NUP50"	"B1AHA4; B2RB15; hsa:10762; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5; Q9UKX7"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	""	"28"	"0"	"215.1"	"127.5"	"224.6"	"203.7"	"204.6"	"180.5"	"244.2"	"2.0"	"1900.5"	"1978.4"	"3873.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6M4"	"Casein kinase I isoform gamma-3 OS=Homo sapiens OX=9606 GN=CSNK1G3 PE=1 SV=2"	"0.000"	""	"11"	"5"	"11"	"2"	"447"	"51.4"	"9.22"	"1471.13"	"23.26"	"2"	"5"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12605"	"1456"	"ENSG00000151292"	"CSNK1G3"	"A8K040; B4DSH2; B7Z9Q4; E7EVD0; hsa:1456; Q86WZ7; Q9Y6M3; Q9Y6M4"	""	"Hedgehog signaling pathway"	"1"	"2"	"57.3"	"42.7"	"80.5"	"67.0"	"74.3"	"79.8"	"135.8"	"11.0"	"1865.5"	"1968.6"	"5221.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TU7"	"Actin-histidine N-methyltransferase OS=Homo sapiens OX=9606 GN=SETD3 PE=1 SV=1"	"0.000"	""	"10"	"5"	"12"	"5"	"594"	"67.2"	"5.96"	"2114.85"	"23.22"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00856, Pf09273"	"84193"	"ENSG00000183576"	"SETD3"	"A0PJU3; A5PLP0; B4DZE8; hsa:84193; Q0VAQ2; Q659C0; Q86TU7; Q86TU8; Q96GY9; Q9H5U5"	"PKMTs methylate histone lysines"	"Histone modifications"	"2"	"0"	"60.9"	"46.0"	"65.2"	"59.4"	"61.4"	"64.7"	"118.8"	"5.9"	"1422.7"	"1484.8"	"3142.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75521"	"Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4"	"0.000"	""	"18"	"5"	"6"	"5"	"394"	"43.6"	"9.00"	"620.53"	"23.21"	"1"	"5"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00378, Pf00887"	"10455"	"ENSG00000198721"	"ECI2"	"hsa:10455; O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1; Q9NYH7; Q9UN55"	""	""	"0"	"0"	"142.3"	"136.6"	"155.7"	"142.6"	"144.0"	"147.1"	"257.7"	"1.9"	"1958.0"	"2057.6"	"4551.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75369"	"Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2"	"0.000"	""	"4"	"6"	"11"	"5"	"2602"	"278.0"	"5.73"	"2083.08"	"23.12"	"5"	"6"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2317"	"ENSG00000136068"	"FLNB"	"B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; hsa:2317; O75369; Q13706; Q59EC2; Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q8WXT3; Q9NRB5; Q9NT26; Q9UEV9"	"ISG15 antiviral mechanism"	"Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; NPHP1 deletion syndrome"	"6"	"0"	"100.9"	"72.1"	"109.9"	"102.3"	"81.4"	"81.9"	"144.5"	"2.7"	"797.2"	"793.1"	"1748.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14625"	"Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1"	"0.000"	""	"11"	"7"	"10"	"7"	"803"	"92.4"	"4.84"	"1364.68"	"23.07"	"4"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"7184"	"ENSG00000166598"	"HSP90B1"	"hsa:7184; P14625; Q96A97"	"Trafficking and processing of endosomal TLR; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Interleukin-4 and Interleukin-13 signaling; Scavenging by Class A Receptors; ATF6 (ATF6-alpha) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"11"	"0"	"154.9"	"126.8"	"180.2"	"169.0"	"179.4"	"160.8"	"237.4"	"2.4"	"1341.5"	"1427.0"	"3095.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99873"	"Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3"	"0.000"	""	"17"	"5"	"8"	"5"	"371"	"42.4"	"5.35"	"626.30"	"23.02"	"2"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13649"	"3276"	"ENSG00000126457"	"PRMT1"	"A0A087X1W2; B4E3C3; G5E9B6; H7C2I1; hsa:3276; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872; Q99873; Q99874; Q9NZ04; Q9NZ05; Q9NZ06"	"Estrogen-dependent gene expression; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Extra-nuclear estrogen signaling; RMTs methylate histone arginines; Maturation of nucleoprotein"	"Energy metabolism; mRNA processing; Nitric oxide metabolism in cystic fibrosis; 16p11.2 distal deletion syndrome; Interferon type I signaling pathways"	"11"	"0"	"38.7"	"30.2"	"57.4"	"48.7"	"47.6"	"30.9"	"77.3"	"13.2"	"936.4"	"971.1"	"2730.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60508"	"Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1"	"0.000"	""	"12"	"7"	"12"	"7"	"579"	"65.5"	"7.06"	"1692.13"	"23.01"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"51362"	"ENSG00000168438"	"CDC40"	"B2RBC5; hsa:51362; O60508; O75471; Q5SRN0; Q9UPG1"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"mRNA processing"	"5"	"0"	"174.0"	"124.9"	"175.4"	"166.7"	"156.7"	"158.1"	"298.4"	"3.6"	"1895.6"	"1967.8"	"4670.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CX2"	"BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1"	"0.000"	""	"25"	"6"	"10"	"6"	"325"	"35.7"	"5.64"	"1822.73"	"22.99"	"4"	"6"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf02214"	"115207"	"ENSG00000178695"	"KCTD12"	"hsa:115207; Q96CX2"	""	""	"0"	"0"	"59.3"	"50.2"	"64.0"	"70.6"	"61.5"	"66.6"	"154.3"	"12.6"	"1412.7"	"1400.0"	"3528.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIG0"	"Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2"	"0.000"	""	"5"	"7"	"11"	"7"	"1483"	"170.8"	"8.48"	"1867.36"	"22.97"	"5"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf00628, Pf10537, Pf15612, Pf15613"	"9031"	"ENSG00000009954"	"BAZ1B"	"B9EGK3; D3DXE9; hsa:9031; O95039; O95247; O95277; Q6P1K4; Q86UJ6; Q9UIG0"	"B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"	"IL-18 signaling pathway; 7q11.23 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome"	"5"	"0"	"243.0"	"213.2"	"242.6"	"258.7"	"228.4"	"259.2"	"538.2"	"11.4"	"2869.1"	"2895.0"	"5552.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z478"	"ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2"	"0.000"	""	"11"	"12"	"18"	"12"	"1369"	"155.1"	"8.09"	"3331.21"	"22.97"	"9"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"54505"	"ENSG00000067248"	"DHX29"	"hsa:54505; O75549; Q63HN0; Q63HN3; Q7Z478; Q8IWW2; Q8N3A1; Q9UMH2"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"77.7"	"54.4"	"79.1"	"77.4"	"74.9"	"80.7"	"215.8"	"5.6"	"1238.9"	"1311.7"	"3055.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y697"	"Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3"	"0.000"	""	"12"	"4"	"10"	"4"	"457"	"50.2"	"8.31"	"2407.26"	"22.90"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00266"	"9054"	"ENSG00000244005"	"NFS1"	"B3KMA5; B4DXK9; E1P5R8; F5GYK5; hsa:9054; Q6P0L8; Q9NTZ5; Q9Y481; Q9Y697"	""	"Iron-sulfur cluster biogenesis"	"1"	"0"	"97.2"	"81.5"	"93.4"	"88.0"	"100.4"	"106.5"	"165.1"	"3.1"	"1438.8"	"1467.0"	"2584.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00403"	"Transcription initiation factor IIB OS=Homo sapiens OX=9606 GN=GTF2B PE=1 SV=1"	"0.000"	""	"22"	"5"	"13"	"5"	"316"	"34.8"	"8.35"	"2206.31"	"22.89"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00382, Pf08271"	"2959"	"ENSG00000137947"	"GTF2B"	"A8K1A7; hsa:2959; Q00403; Q5JS30"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"Eukaryotic transcription initiation"	"10"	"0"	"78.7"	"73.6"	"93.3"	"83.4"	"95.9"	"83.6"	"159.3"	"0.0"	"1437.0"	"1499.9"	"2649.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQG5"	"Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1"	"0.000"	""	"23"	"7"	"15"	"5"	"326"	"36.9"	"5.97"	"3256.90"	"22.88"	"7"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"58490"	"ENSG00000101413"	"RPRD1B"	"hsa:58490; Q1WDE7; Q6PKF4; Q9NQG5"	"RNA polymerase II transcribes snRNA genes"	"Modulators of TCR signaling and T cell activation"	"2"	"0"	"54.4"	"28.1"	"56.7"	"40.9"	"48.9"	"42.6"	"116.2"	"8.8"	"1059.6"	"1242.7"	"2732.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23193"	"Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2"	"0.000"	""	"27"	"8"	"15"	"8"	"301"	"33.9"	"8.38"	"2790.16"	"22.85"	"7"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6917"	"ENSG00000187735"	"TCEA1"	"A6NF25; A8K339; hsa:6917; P23193; Q15563; Q6FG87"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	""	"15"	"0"	"249.0"	"181.9"	"252.2"	"237.3"	"240.1"	"207.8"	"433.5"	"5.4"	"2862.4"	"3106.9"	"5722.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43427"	"Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3"	"0.000"	""	"17"	"7"	"12"	"7"	"364"	"41.9"	"6.48"	"1677.81"	"22.84"	"4"	"6"	"signal transduction"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05427"	"9158"	"ENSG00000172500"	"FIBP"	"A8K0J7; hsa:9158; O43427; Q27Q85; Q6IBQ3; Q9HD65"	""	"Modulators of TCR signaling and T cell activation"	"1"	"0"	"77.4"	"51.2"	"90.2"	"84.3"	"90.2"	"84.6"	"179.1"	"0.0"	"3424.4"	"3496.7"	"6107.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67870"	"Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1"	"0.000"	""	"20"	"3"	"10"	"3"	"215"	"24.9"	"5.55"	"2122.00"	"22.83"	"3"	"3"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf01214"	"1460"	"ENSG00000204435; ENSG00000206406; ENSG00000224398; ENSG00000224774; ENSG00000228875; ENSG00000230700; ENSG00000232960"	"CSNK2B"	"B0UXA9; hsa:1460; P07312; P13862; P67870; Q4VX47"	"Neutrophil degranulation; Condensation of Prometaphase Chromosomes; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Synthesis of PC"	"Alzheimer's disease and miRNA effects; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"19"	"0"	"144.5"	"119.3"	"109.5"	"131.6"	"121.2"	"55.1"	"378.1"	"3.4"	"960.9"	"961.6"	"2608.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13310"	"Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1"	"0.000"	""	"12"	"6"	"12"	"2"	"644"	"70.7"	"9.26"	"2228.09"	"22.82"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"8761"	"ENSG00000090621"	"PABPC4"	"B1ANQ8; hsa:8761; Q13310; Q4VC03; Q6P0N3"	""	""	"0"	"0"	"86.4"	"63.2"	"77.1"	"67.6"	"78.9"	"57.8"	"170.7"	"0.0"	"706.5"	"652.0"	"1261.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32969"	"60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1"	"0.000"	""	"29"	"5"	"10"	"5"	"192"	"21.9"	"9.95"	"1223.14"	"22.80"	"3"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00347"	"6133"	"ENSG00000163682"	"RPL9; RPL9P7; RPL9P8; RPL9P9"	"hsa:6133; P32969"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"86.6"	"81.0"	"87.7"	"78.9"	"75.3"	"78.3"	"283.2"	"4.5"	"1309.3"	"1476.0"	"3021.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19367"	"Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3"	"0.000"	""	"10"	"7"	"12"	"5"	"917"	"102.4"	"6.80"	"2464.58"	"22.77"	"6"	"6"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3098"	"ENSG00000156515"	"HK1"	"E9PCK0; hsa:3098; O43443; O43444; O75574; P19367; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5"	"Glycolysis; Defective HK1 causes hexokinase deficiency (HK deficiency)"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Disorders of fructose metabolism; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"12"	"1"	"88.9"	"76.9"	"100.6"	"88.6"	"77.3"	"75.0"	"146.9"	"3.8"	"1520.6"	"1743.6"	"3209.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NNW5"	"WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1"	"0.000"	""	"9"	"7"	"12"	"7"	"1121"	"121.6"	"6.87"	"1993.14"	"22.75"	"6"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00400"	"11180"	"ENSG00000178252"	"WDR6"	"B4DHK2; hsa:11180; Q3MIT1; Q9NNW5; Q9UF63"	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	""	"5"	"0"	"143.2"	"93.8"	"148.8"	"130.3"	"132.3"	"132.2"	"224.2"	"0.0"	"2007.2"	"2169.0"	"4720.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19388"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4"	"0.000"	""	"28"	"6"	"14"	"6"	"210"	"24.5"	"5.95"	"2498.27"	"22.72"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01191, Pf03871"	"5434"	"ENSG00000099817"	"POLR2E"	"B2R6L4; D6W5Y1; hsa:5434; O43380; P19388; Q6PIH5; Q9BT06"	"mRNA Splicing - Major Pathway; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"57"	"0"	"184.8"	"178.5"	"197.8"	"193.2"	"194.5"	"255.7"	"488.6"	"16.7"	"2651.5"	"2588.6"	"4234.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQB8"	"Brain-specific angiogenesis inhibitor 1-associated protein 2 OS=Homo sapiens OX=9606 GN=BAIAP2 PE=1 SV=1"	"0.000"	""	"13"	"6"	"12"	"6"	"552"	"60.8"	"8.90"	"2488.08"	"22.63"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf07653, Pf08397"	"10458"	"ENSG00000175866"	"BAIAP2"	"hsa:10458; O43858; Q53HB1; Q86WC1; Q8N5C0; Q96CR7; Q9UBR3; Q9UQ43; Q9UQB8"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"Regulation of actin cytoskeleton"	"8"	"0"	"94.0"	"80.0"	"91.1"	"83.9"	"76.2"	"92.4"	"253.1"	"22.8"	"2589.2"	"2469.7"	"4104.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62280"	"40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3"	"0.000"	""	"39"	"7"	"14"	"7"	"158"	"18.4"	"10.30"	"2610.83"	"22.61"	"7"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00366, Pf16205"	"6205"	"ENSG00000142534"	"RPS11"	"B2R4F5; hsa:6205; P04643; P62280; Q498Y6; Q6IRY0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Cytoplasmic ribosomal proteins"	"21"	"0"	"606.4"	"451.1"	"648.7"	"577.2"	"553.7"	"501.0"	"1300.6"	"6.6"	"3290.4"	"3204.3"	"6038.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YQ8"	"Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2"	"0.000"	""	"19"	"9"	"11"	"8"	"564"	"63.1"	"5.96"	"1292.27"	"22.45"	"4"	"7"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00168, Pf07002"	"144402"	"ENSG00000139117"	"CPNE8"	"hsa:144402; Q2TB41; Q86VY2; Q86YQ8"	"CDC42 GTPase cycle; RHOQ GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle"	""	"4"	"0"	"64.3"	"42.8"	"88.8"	"72.1"	"82.5"	"73.1"	"130.3"	"1.7"	"2435.9"	"2537.5"	"5878.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60660"	"Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2"	"0.000"	""	"41"	"5"	"11"	"5"	"151"	"16.9"	"4.65"	"2094.22"	"22.40"	"4"	"5"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4637"	"ENSG00000092841"	"MYL6"	"hsa:4637; P16475; P24572; P24573; P60660; Q12790; Q561V9; Q6IAZ0; Q6IPY5"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"Ciliary landscape"	"8"	"0"	"71.2"	"50.9"	"62.2"	"58.4"	"66.1"	"50.0"	"128.3"	"0.3"	"1570.1"	"1602.2"	"4044.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYL9"	"Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1"	"0.000"	""	"21"	"5"	"10"	"5"	"352"	"39.6"	"5.19"	"2316.93"	"22.35"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"29766"	"ENSG00000138594"	"TMOD3"	"B2R6G7; hsa:29766; Q9NT43; Q9NYL9; Q9NZR0"	"Striated Muscle Contraction; RND3 GTPase cycle; RHOBTB2 GTPase cycle"	"VEGFA-VEGFR2 signaling"	"4"	"0"	"168.3"	"121.8"	"153.5"	"133.4"	"133.1"	"135.4"	"332.1"	"3.2"	"1449.6"	"1377.7"	"2662.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14715"	"RANBP2-like and GRIP domain-containing protein 8 OS=Homo sapiens OX=9606 GN=RGPD8 PE=1 SV=2"	"0.000"	""	"4"	"7"	"14"	"1"	"1765"	"198.9"	"6.49"	"2362.44"	"22.32"	"7"	"7"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf00638, Pf01465, Pf16704"	"727851"	"ENSG00000169629"	"RGPD8"	"hsa:727851; O14715; Q5CZA8"	""	"2q13 copy number variation syndrome"	"1"	"0"	"14.4"	"8.3"	"9.5"	"10.0"	"11.2"	"11.3"	"15.2"	"1.7"	"96.1"	"109.3"	"174.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4Z0"	"U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1"	"0.000"	""	"33"	"7"	"14"	"7"	"139"	"15.3"	"9.99"	"2963.03"	"22.31"	"7"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"25804"	"ENSG00000130520"	"LSM4"	"hsa:25804; Q9Y4Z0"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"Ciliary landscape"	"3"	"0"	"235.8"	"192.1"	"219.0"	"228.2"	"244.4"	"209.7"	"508.2"	"4.4"	"1778.7"	"1790.0"	"4454.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14554"	"Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1"	"0.000"	""	"17"	"8"	"15"	"8"	"519"	"59.6"	"7.91"	"2471.77"	"22.30"	"8"	"7"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00085"	"10954"	"ENSG00000065485"	"PDIA5"	"D3DN95; hsa:10954; Q14554; Q9BV43"	"XBP1(S) activates chaperone genes"	""	"1"	"0"	"111.1"	"121.5"	"118.4"	"118.2"	"125.9"	"126.5"	"283.5"	"23.5"	"4512.8"	"4283.7"	"6320.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQG0"	"Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2"	"0.000"	""	"7"	"7"	"12"	"7"	"1328"	"148.8"	"9.28"	"1866.12"	"22.27"	"6"	"6"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04931"	"10514"	"ENSG00000132382"	"MYBBP1A"	"hsa:10514; Q86VM3; Q9BQG0; Q9BW49; Q9P0V5; Q9UF99"	"B-WICH complex positively regulates rRNA expression"	"Energy metabolism; 10q11.21q11.23 copy number variation syndrome"	"3"	"0"	"54.8"	"44.4"	"54.3"	"52.9"	"55.8"	"53.9"	"161.0"	"0.0"	"538.5"	"525.8"	"1046.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37108"	"Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2"	"0.000"	""	"37"	"7"	"20"	"7"	"136"	"14.6"	"10.04"	"4501.91"	"22.22"	"7"	"5"	"transport"	"non-structural extracellular;cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02290"	"6727"	"ENSG00000140319"	"SRP14"	"B5BUF5; hsa:6727; P37108; Q6B0K5; Q96Q14"	"SRP-dependent cotranslational protein targeting to membrane; Neutrophil degranulation"	""	"2"	"0"	"437.0"	"408.8"	"478.4"	"439.8"	"366.3"	"395.0"	"922.4"	"25.5"	"11267.8"	"11108.2"	"13300.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99496"	"E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1"	"0.000"	""	"24"	"6"	"10"	"4"	"336"	"37.6"	"6.84"	"1280.74"	"22.12"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13923, Pf16207"	"6045"	"ENSG00000121481"	"RNF2"	"B2RBS7; B3KRH1; hsa:6045; Q5TEN1; Q5TEN2; Q99496"	"Transcriptional Regulation by E2F6; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"11"	"2"	"46.6"	"44.8"	"59.0"	"56.5"	"61.4"	"60.8"	"105.2"	"0.7"	"920.9"	"1002.4"	"1802.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UG63"	"ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2"	"0.000"	""	"14"	"6"	"10"	"6"	"623"	"71.2"	"7.37"	"2235.16"	"22.08"	"5"	"5"	""	""	"other molecular function"	"Pf00005, Pf12848"	"10061; 114483834"	"ENSG00000033050"	"ABCF2"	"hsa:10061; hsa:114483834; O60864; Q75MJ0; Q75MJ1; Q96TE8; Q9UG63"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"72.6"	"60.5"	"73.0"	"79.7"	"59.1"	"65.6"	"138.0"	"4.0"	"1351.0"	"1377.7"	"3078.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13356"	"RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1"	"0.000"	""	"15"	"6"	"10"	"6"	"520"	"58.8"	"8.78"	"1530.82"	"22.01"	"4"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"23759"	"ENSG00000100023"	"PPIL2"	"hsa:23759; Q13356; Q13357; Q8TAH2; Q9BWR8"	"mRNA Splicing - Major Pathway; Basigin interactions"	""	"2"	"0"	"135.5"	"123.6"	"145.7"	"133.1"	"123.0"	"163.1"	"330.4"	"8.4"	"1459.3"	"1453.9"	"3363.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18124"	"60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1"	"0.000"	""	"29"	"7"	"14"	"7"	"248"	"29.2"	"10.65"	"2802.26"	"21.96"	"7"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00327, Pf08079"	"6129"	"ENSG00000147604"	"RPL7"	"A8K504; hsa:6129; P18124; Q15289; Q3KQU0; Q5I0X1; Q6IBM9"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"92.6"	"73.9"	"91.6"	"79.0"	"85.6"	"96.2"	"394.1"	"9.5"	"1720.7"	"1804.0"	"3437.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02543"	"60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2"	"0.000"	""	"34"	"6"	"12"	"6"	"176"	"20.7"	"10.71"	"1783.72"	"21.88"	"4"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01775"	"6142"	"ENSG00000105640"	"RPL18A"	"hsa:6142; Q02543"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"318.3"	"304.3"	"325.9"	"348.4"	"299.8"	"293.9"	"1337.4"	"12.7"	"3727.8"	"3597.5"	"6513.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WW12"	"PEST proteolytic signal-containing nuclear protein OS=Homo sapiens OX=9606 GN=PCNP PE=1 SV=2"	"0.000"	""	"29"	"5"	"12"	"5"	"178"	"18.9"	"7.49"	"2006.01"	"21.83"	"4"	"4"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	""	"Pf15473"	"57092"	"ENSG00000081154"	"PCNP"	"B2RBE7; D3DN52; hsa:57092; Q53GF3; Q6AI44; Q8WW12; Q96CU3; Q9NS81"	""	""	"0"	"0"	"317.0"	"252.5"	"349.2"	"327.2"	"259.9"	"303.7"	"764.1"	"1.3"	"3343.3"	"3516.3"	"7563.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4F1"	"FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FARP1 PE=1 SV=1"	"0.000"	""	"6"	"6"	"11"	"6"	"1045"	"118.6"	"8.15"	"1974.25"	"21.79"	"5"	"6"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"10160"	"ENSG00000152767"	"FARP1"	"hsa:10160; Q5JVI9; Q6IQ29; Q9Y4F1"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOF GTPase cycle"	""	"4"	"0"	"109.9"	"82.2"	"93.2"	"81.9"	"82.0"	"84.3"	"181.7"	"1.6"	"1425.5"	"1482.9"	"3657.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14011"	"Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1"	"0.000"	""	"35"	"4"	"9"	"4"	"172"	"18.6"	"9.51"	"1345.99"	"21.76"	"3"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1153"	"ENSG00000099622"	"CIRBP"	"B3KT17; B4E2X2; hsa:1153; Q14011"	""	""	"0"	"0"	"268.2"	"248.7"	"236.3"	"246.6"	"201.2"	"243.8"	"726.5"	"3.6"	"1143.4"	"1118.6"	"1768.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP1"	"Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1"	"0.000"	""	"16"	"4"	"7"	"4"	"358"	"39.4"	"4.86"	"811.52"	"21.73"	"2"	"4"	"cell cycle OR cell proliferation;other biological processes"	"other cell component"	""	"Pf04194"	"84306"	"ENSG00000126249"	"PDCD2L"	"hsa:84306; Q9BRP1"	""	""	"0"	"0"	"23.4"	"17.3"	"29.5"	"27.9"	"29.6"	"32.6"	"54.4"	"0.0"	"463.7"	"448.2"	"834.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RF0"	"Sorting nexin-18 OS=Homo sapiens OX=9606 GN=SNX18 PE=1 SV=2"	"0.000"	""	"13"	"6"	"10"	"6"	"628"	"68.9"	"5.68"	"1565.16"	"21.64"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00787, Pf10456, Pf14604"	"112574"	"ENSG00000178996"	"SNX18"	"B4E2B3; H7BXX3; hsa:112574; Q05BB3; Q0VG02; Q96RF0"	"Clathrin-mediated endocytosis"	""	"1"	"0"	"110.8"	"74.4"	"127.9"	"97.1"	"105.4"	"127.1"	"256.7"	"5.0"	"2312.5"	"2260.5"	"2832.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4G4"	"Golgi-associated plant pathogenesis-related protein 1 OS=Homo sapiens OX=9606 GN=GLIPR2 PE=1 SV=3"	"0.000"	""	"35"	"4"	"10"	"4"	"154"	"17.2"	"9.41"	"2315.83"	"21.60"	"4"	"4"	"other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf00188"	"152007"	"ENSG00000122694"	"GLIPR2"	"hsa:152007; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36; Q9H4G4"	""	""	"0"	"0"	"120.5"	"119.9"	"137.8"	"127.0"	"101.0"	"138.4"	"539.7"	"0.0"	"2035.0"	"2129.1"	"3419.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46776"	"60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2"	"0.000"	""	"28"	"5"	"13"	"5"	"148"	"16.6"	"11.00"	"2737.26"	"21.58"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf00828"	"6157"	"ENSG00000166441"	"RPL27A"	"B2R4B3; hsa:6157; P46776"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"246.0"	"168.3"	"245.1"	"216.5"	"240.5"	"176.8"	"601.7"	"2.6"	"1983.8"	"1912.4"	"3747.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15185"	"Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1"	"0.000"	""	"42"	"6"	"10"	"6"	"160"	"18.7"	"4.54"	"1992.52"	"21.54"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969"	"10728"	"ENSG00000110958"	"PTGES3"	"A8K7D0; B4DHP2; B4DP11; B4DP21; hsa:10728; Q15185; Q8WU70"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Estrogen-dependent gene expression; Potential therapeutics for SARS; HSF1 activation; Aryl hydrocarbon receptor signalling; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Attenuation phase"	"Aryl hydrocarbon receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"11"	"0"	"1360.3"	"978.0"	"1286.6"	"1333.8"	"1217.4"	"977.2"	"1757.1"	"0.0"	"2664.5"	"2514.5"	"3583.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96Q89"	"Kinesin-like protein KIF20B OS=Homo sapiens OX=9606 GN=KIF20B PE=1 SV=3"	"0.000"	""	"4"	"5"	"10"	"5"	"1820"	"210.5"	"5.67"	"1820.75"	"21.54"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"9585"	"ENSG00000138182"	"KIF20B"	"A8MXM7; hsa:9585; O43277; Q09471; Q2KQ73; Q32NE1; Q561V3; Q58EX8; Q5T9M8; Q5T9M9; Q5T9N0; Q5T9N1; Q7KZ68; Q7Z5E0; Q7Z5E1; Q7Z6M9; Q86X82; Q96Q89; Q9H3R8; Q9H6Q9; Q9H755; Q9NTC1; Q9UFR5"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"Gastric cancer network 1"	"3"	"0"	"27.4"	"23.6"	"26.8"	"25.7"	"17.9"	"19.6"	"78.5"	"5.5"	"432.5"	"440.8"	"888.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60306"	"RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4"	"0.000"	""	"5"	"6"	"10"	"6"	"1485"	"171.2"	"6.37"	"1678.47"	"21.51"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13086, Pf13087, Pf16399"	"9716"	"ENSG00000021776"	"AQR"	"A0JP17; A5YKK3; hsa:9716; O60306; Q2YDX9; Q6IRU8; Q6PIC8"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	""	"5"	"0"	"76.3"	"59.6"	"78.2"	"79.5"	"80.7"	"71.6"	"149.8"	"5.6"	"1160.8"	"1266.2"	"3016.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14562"	"ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1"	"0.000"	""	"7"	"8"	"15"	"7"	"1220"	"139.2"	"8.32"	"2630.93"	"21.46"	"8"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00271, Pf00575, Pf04408, Pf07717"	"1659"	"ENSG00000067596"	"DHX8"	"hsa:1659; Q14562"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"34.5"	"19.8"	"37.2"	"34.4"	"38.0"	"26.8"	"84.1"	"0.0"	"951.9"	"978.6"	"2333.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22087"	"rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2"	"0.000"	""	"24"	"6"	"10"	"6"	"321"	"33.8"	"10.18"	"1984.44"	"21.38"	"5"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01269"	"2091"	"ENSG00000105202; ENSG00000280548"	"FBL"	"B5BUE8; hsa:2091; O75259; P22087; Q6IAT5; Q9UPI6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"128.4"	"103.2"	"119.8"	"114.0"	"97.0"	"92.3"	"287.8"	"4.4"	"1108.6"	"1086.5"	"2274.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD6"	"39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2"	"0.000"	""	"25"	"6"	"8"	"6"	"325"	"36.9"	"8.78"	"1042.87"	"21.38"	"3"	"5"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00687"	"65008"	"ENSG00000169288"	"MRPL1"	"A6NG03; hsa:65008; Q4W5B8; Q6IAG4; Q96BW3; Q9BYD6; Q9H793; Q9NRL5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"103.2"	"74.2"	"113.2"	"102.5"	"109.5"	"113.7"	"250.0"	"11.7"	"2589.6"	"2621.2"	"5118.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15381"	"Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1"	"0.000"	""	"9"	"6"	"12"	"6"	"856"	"95.0"	"6.48"	"1976.14"	"21.35"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00004, Pf16725, Pf17862"	"4931"	"ENSG00000143748"	"NVL"	"B4DMC4; B4DP98; hsa:4931; O15381; Q96EM7"	""	""	"0"	"0"	"127.9"	"92.1"	"135.8"	"132.9"	"125.2"	"104.7"	"284.9"	"2.5"	"1740.6"	"1745.3"	"3659.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06899"	"Histone H2B type 1-J OS=Homo sapiens OX=9606 GN=H2BC11 PE=1 SV=3"	"0.000"	""	"35"	"4"	"12"	"1"	"126"	"13.9"	"10.32"	"2359.09"	"21.29"	"4"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8970"	"ENSG00000124635"	"H2BC11"	"B2R4J4; hsa:8970; O60816; P06899"	"Ub-specific processing proteases; E3 ubiquitin ligases ubiquitinate target proteins; Deposition of new CENPA-containing nucleosomes at the centromere; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	""	"43"	"0"	"68.1"	"90.6"	"23.0"	"38.5"	"38.3"	"50.7"	"263.1"	"0.0"	"1005.5"	"1244.6"	"1934.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15075"	"Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2"	"0.000"	""	"6"	"7"	"11"	"7"	"1411"	"162.4"	"5.68"	"2183.66"	"21.27"	"5"	"6"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363"	"8411"	"ENSG00000102189"	"EEA1"	"hsa:8411; Q14221; Q15075"	"Toll Like Receptor 9 (TLR9) Cascade"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"18.1"	"13.6"	"30.6"	"18.5"	"16.4"	"23.5"	"70.5"	"14.9"	"1381.4"	"1282.5"	"2615.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60814"	"Histone H2B type 1-K OS=Homo sapiens OX=9606 GN=H2BC12 PE=1 SV=3"	"0.000"	""	"36"	"5"	"13"	"2"	"126"	"13.9"	"10.32"	"2842.88"	"21.22"	"5"	"4"	"stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"85236"	"ENSG00000197903"	"H2BC12"	"A8K7P7; hsa:85236; O60814; Q2VPI7"	"Ub-specific processing proteases; HATs acetylate histones; E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	""	"43"	"4"	"238.4"	"240.1"	"184.9"	"183.7"	"179.2"	"206.0"	"893.0"	"8.7"	"1929.5"	"2223.8"	"3464.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46063"	"ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3"	"0.000"	""	"9"	"4"	"9"	"4"	"649"	"73.4"	"7.88"	"1579.06"	"21.17"	"4"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf16124"	"5965"	"ENSG00000004700"	"RECQL"	"A8K6G2; hsa:5965; P46063"	""	"Progeria-associated lipodystrophy"	"1"	"0"	"40.9"	"26.5"	"47.1"	"44.9"	"48.6"	"47.6"	"113.4"	"5.4"	"805.4"	"715.1"	"1753.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H078"	"Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1"	"0.000"	""	"10"	"6"	"10"	"6"	"707"	"78.7"	"9.01"	"1577.41"	"21.16"	"4"	"6"	"stress response;signal transduction;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf07724, Pf10431, Pf12796, Pf13857"	"81570"	"ENSG00000162129"	"CLPB"	"B4DXJ7; B4DXP7; B4DXW4; E7EWN6; F8W7P6; hsa:81570; Q8ND11; Q9H078; Q9H8Y0"	""	""	"0"	"0"	"110.8"	"78.5"	"127.9"	"116.1"	"110.0"	"104.9"	"231.3"	"8.8"	"2294.9"	"2367.6"	"5552.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVM6"	"DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1"	"0.000"	""	"20"	"5"	"10"	"5"	"304"	"34.7"	"8.53"	"2317.74"	"21.12"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00226"	"55192"	"ENSG00000104129"	"DNAJC17"	"hsa:55192; Q9NVM6"	""	""	"0"	"0"	"57.9"	"42.0"	"72.1"	"61.2"	"57.1"	"72.6"	"165.2"	"8.3"	"1822.9"	"1871.2"	"3879.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13136"	"Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1"	"0.000"	""	"8"	"7"	"12"	"4"	"1202"	"135.7"	"6.29"	"2758.06"	"21.09"	"6"	"5"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8500"	"ENSG00000131626"	"PPFIA1"	"A6NLE3; hsa:8500; Q13135; Q13136; Q14567; Q8N4I2"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	""	"6"	"1"	"92.8"	"66.0"	"83.1"	"74.3"	"68.4"	"95.7"	"135.0"	"1.6"	"1206.2"	"1165.2"	"2082.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14241"	"Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2"	"0.000"	""	"8"	"5"	"11"	"5"	"798"	"89.9"	"9.57"	"2729.91"	"21.06"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06881, Pf08711"	"6924"	"ENSG00000011007"	"ELOA"	"B2R7Q8; hsa:6924; Q14241; Q8IXH1"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation"	"VEGFA-VEGFR2 signaling; 10q11.21q11.23 copy number variation syndrome"	"13"	"0"	"190.3"	"157.1"	"198.3"	"188.8"	"181.1"	"214.7"	"466.5"	"16.3"	"3686.4"	"3453.4"	"6174.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99426"	"Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2"	"0.000"	""	"27"	"5"	"10"	"5"	"244"	"27.3"	"5.15"	"1673.85"	"21.01"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14560"	"1155"	"ENSG00000105254"	"TBCB"	"hsa:1155; O00111; O00674; O14728; Q6FGY5; Q99426"	"Post-chaperonin tubulin folding pathway"	""	"1"	"0"	"40.2"	"14.5"	"47.4"	"35.4"	"44.5"	"55.9"	"50.7"	"1.7"	"584.6"	"589.1"	"2089.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31689"	"DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2"	"0.000"	""	"23"	"6"	"10"	"5"	"397"	"44.8"	"7.08"	"1207.07"	"21.00"	"4"	"6"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf00684, Pf01556"	"3301"	"ENSG00000086061"	"DNAJA1"	"hsa:3301; P31689; Q5T7Q0; Q86TL9"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"3"	"1"	"75.6"	"57.2"	"94.1"	"87.6"	"86.9"	"80.9"	"115.0"	"5.3"	"2542.6"	"2562.0"	"4849.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UFW8"	"CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2"	"0.000"	""	"29"	"4"	"10"	"4"	"167"	"18.8"	"8.95"	"1740.75"	"20.96"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"8545"	"ENSG00000163320"	"CGGBP1"	"D3DU38; hsa:8545; O15183; Q9UFW8"	""	""	"0"	"0"	"112.5"	"95.8"	"130.9"	"132.9"	"123.2"	"123.9"	"299.4"	"5.9"	"1475.3"	"1363.8"	"3185.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5S9"	"RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1"	"0.000"	""	"22"	"3"	"10"	"3"	"174"	"19.9"	"5.72"	"2813.73"	"20.93"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"9939"	"ENSG00000265241"	"RBM8A"	"B3KQI9; hsa:9939; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4; Q9Y5S9"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	""	"6"	"0"	"81.4"	"78.2"	"69.1"	"79.1"	"61.7"	"82.0"	"242.4"	"0.0"	"730.6"	"771.9"	"1729.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KP1"	"Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1"	"0.000"	""	"9"	"6"	"13"	"6"	"924"	"104.0"	"6.90"	"2771.78"	"20.90"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01833, Pf15469"	"55770"	"ENSG00000112685"	"EXOC2"	"B2RBE6; hsa:55770; Q5JPC8; Q96AN6; Q96KP1; Q9NUZ8; Q9UJM7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Ciliary landscape"	"7"	"0"	"4.2"	"4.1"	"14.3"	"10.0"	"15.2"	"14.1"	"34.4"	"6.6"	"803.0"	"777.3"	"1599.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UN86"	"Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2"	"0.000"	""	"13"	"5"	"11"	"5"	"482"	"54.1"	"5.55"	"1776.92"	"20.83"	"4"	"5"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"9908"	"ENSG00000138757"	"G3BP2"	"A8K6X1; hsa:9908; O60606; O75149; Q9UN86; Q9UPA1"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"1"	"0"	"372.8"	"263.4"	"366.3"	"329.6"	"276.7"	"338.4"	"648.0"	"17.2"	"2298.2"	"2215.8"	"4859.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYD1"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2"	"0.000"	""	"9"	"6"	"11"	"1"	"628"	"68.8"	"5.43"	"1372.63"	"20.83"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf07145"	"23708"	"ENSG00000189369"	"GSPT2"	"hsa:23708; Q8IYD1; Q9H909; Q9NVY0; Q9NY44"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Translation factors"	"5"	"0"	"5.4"	"3.2"	"8.0"	"6.9"	"8.1"	"5.6"	"7.6"	"0.0"	"540.7"	"508.2"	"1290.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22059"	"Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1"	"0.000"	""	"6"	"5"	"7"	"5"	"807"	"89.4"	"7.30"	"942.12"	"20.81"	"2"	"5"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"5007"	"ENSG00000110048"	"OSBP"	"hsa:5007; P22059; Q6P524"	"Sphingolipid de novo biosynthesis; Synthesis of bile acids and bile salts"	""	"2"	"0"	"32.1"	"17.2"	"40.1"	"33.7"	"37.8"	"33.6"	"56.0"	"6.6"	"836.3"	"854.8"	"2116.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEW8"	"STE20/SPS1-related proline-alanine-rich protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3"	"0.000"	""	"10"	"3"	"10"	"2"	"545"	"59.4"	"6.29"	"2009.31"	"20.79"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"27347"	"ENSG00000198648"	"STK39"	"hsa:27347; O14774; Q53S90; Q53SL7; Q53SS1; Q9UER4; Q9UEW8; X5D9C8"	""	""	"0"	"0"	"27.7"	"17.9"	"27.4"	"27.2"	"26.5"	"23.1"	"41.9"	"3.7"	"223.7"	"214.6"	"489.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99613"	"Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1"	"0.000"	""	"6"	"5"	"11"	"5"	"913"	"105.3"	"5.68"	"1844.39"	"20.74"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01399, Pf05470"	"8663"	"ENSG00000184110"	"EIF3C"	"A8K7Z0; B2RXG3; B4E1D5; H3BRV0; hsa:8663; O00215; Q99613; Q9BW98"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"97.3"	"86.6"	"115.1"	"93.8"	"103.1"	"122.0"	"158.7"	"1.7"	"653.1"	"725.7"	"1886.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A33"	"Coiled-coil domain-containing protein 47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1"	"0.000"	""	"14"	"6"	"10"	"6"	"483"	"55.8"	"4.87"	"994.79"	"20.72"	"2"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"translation activity;other molecular function"	"Pf07946"	"57003"	"ENSG00000108588"	"CCDC47"	"B2RAS8; D3DU20; hsa:57003; Q96A33; Q96D00; Q96JZ7; Q9H3E4; Q9NRG3"	""	""	"0"	"0"	"99.9"	"71.5"	"100.3"	"92.9"	"96.9"	"106.9"	"143.2"	"2.1"	"1482.9"	"1570.1"	"3787.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53621"	"Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2"	"0.000"	""	"5"	"6"	"13"	"6"	"1224"	"138.3"	"7.66"	"1878.52"	"20.65"	"5"	"6"	"transport;signal transduction"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf04053, Pf06957, Pf12894"	"1314"	"ENSG00000122218"	"COPA"	"hsa:1314; P53621; Q5T201; Q8IXZ9"	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	""	"2"	"0"	"157.8"	"107.7"	"162.6"	"145.6"	"138.2"	"114.5"	"246.2"	"6.0"	"1709.4"	"1756.3"	"4260.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61201"	"COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1"	"0.000"	""	"14"	"5"	"9"	"5"	"443"	"51.6"	"5.53"	"1708.02"	"20.51"	"4"	"5"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"9318"	"ENSG00000166200"	"COPS2"	"hsa:9318; O88950; P61201; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"Ciliary landscape"	"6"	"0"	"37.3"	"35.5"	"50.6"	"47.3"	"44.6"	"47.7"	"119.1"	"8.8"	"1019.8"	"1112.0"	"2543.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34932"	"Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4"	"0.000"	""	"9"	"6"	"10"	"5"	"840"	"94.3"	"5.19"	"2213.71"	"20.46"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00012"	"3308"	"ENSG00000170606"	"HSPA4"	"hsa:3308; O95756; P34932; Q2TAL4; Q9BUK9"	"Regulation of HSF1-mediated heat shock response"	"Parkin-ubiquitin proteasomal system pathway"	"2"	"1"	"41.7"	"41.3"	"52.1"	"45.4"	"53.6"	"44.5"	"93.9"	"5.7"	"693.1"	"731.9"	"1476.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55769"	"NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3"	"0.000"	""	"54"	"5"	"9"	"5"	"128"	"14.2"	"8.46"	"1402.94"	"20.45"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01248"	"4809"	"ENSG00000100138"	"SNU13"	"hsa:4809; P55769"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"mRNA processing"	"4"	"0"	"55.7"	"53.2"	"66.3"	"55.7"	"53.9"	"40.0"	"142.3"	"5.5"	"1038.7"	"987.4"	"1988.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0K7"	"Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2"	"0.000"	""	"7"	"6"	"11"	"5"	"980"	"110.0"	"6.21"	"1756.31"	"20.44"	"5"	"6"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00023, Pf12796"	"26064"	"ENSG00000039560"	"RAI14"	"E9PED3; hsa:26064; Q6V1W9; Q7Z5I4; Q7Z733; Q9P0K7; Q9P2L2; Q9Y3T5"	""	""	"0"	"0"	"53.3"	"37.7"	"59.7"	"57.6"	"56.7"	"57.6"	"136.1"	"1.5"	"2490.7"	"2612.9"	"4837.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SI9"	"Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1"	"0.000"	""	"8"	"5"	"9"	"2"	"672"	"73.6"	"8.72"	"1708.50"	"20.42"	"4"	"5"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf00035, Pf07528"	"55342"	"ENSG00000165209"	"STRBP"	"hsa:55342; Q32NB9; Q96SI9; Q9BUE1; Q9BXG4; Q9H0B4; Q9H7V1; Q9NUK4"	""	""	"0"	"0"	"70.0"	"59.5"	"74.9"	"71.3"	"77.3"	"77.0"	"154.3"	"0.0"	"626.5"	"651.9"	"1313.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI36"	"WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1"	"0.000"	""	"7"	"5"	"10"	"5"	"951"	"105.3"	"7.53"	"1877.84"	"20.41"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf04192, Pf12894"	"134430"	""	"WDR36"	"A2RUS4; hsa:134430; Q68E02; Q8N1Q2; Q8NI36"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"69.1"	"52.0"	"81.4"	"79.6"	"77.8"	"69.1"	"122.6"	"0.0"	"1145.5"	"1222.0"	"2791.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4G0J3"	"La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1"	"0.000"	""	"12"	"6"	"11"	"6"	"582"	"66.9"	"9.55"	"2073.62"	"20.39"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"51574"	"ENSG00000174720"	"LARP7"	"B2ZHN6; hsa:51574; Q3B7A9; Q4G0J3; Q9P1S7; Q9Y3Z8"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"130.6"	"127.2"	"145.6"	"138.4"	"97.6"	"106.3"	"277.1"	"7.7"	"783.3"	"738.9"	"1224.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ66"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 OS=Homo sapiens OX=9606 GN=PLCB1 PE=1 SV=1"	"0.000"	""	"5"	"4"	"10"	"4"	"1216"	"138.5"	"6.23"	"2266.71"	"20.39"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00387, Pf00388, Pf06631, Pf08703, Pf09279, Pf17787"	"23236"	"ENSG00000182621"	"PLCB1"	"D3DW12; D3DW13; hsa:23236; O60325; Q17RQ6; Q5TFF7; Q5TGC9; Q8IV93; Q9BQW2; Q9H4H2; Q9H8H5; Q9NQ65; Q9NQ66; Q9NQH9; Q9NTH4; Q9UJP6; Q9UM26"	"Ca2+ pathway; G alpha (q) signalling events; G beta:gamma signalling through PLC beta; Presynaptic function of Kainate receptors; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion; Synthesis of IP3 and IP4 in the cytosol; PLC beta mediated events; Acetylcholine regulates insulin secretion"	"AMP-activated protein kinase signaling; Thyroid stimulating hormone (TSH) signaling pathway; Alzheimer's disease and miRNA effects; Endothelin pathways; S1P receptor signal transduction; Cell-type dependent selectivity of CCK2R signaling; Chemokine signaling pathway; GPR40 pathway; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Hippo signaling regulation pathways; Fragile X syndrome; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Airway smooth muscle cell contraction; Neuroinflammation and glutamatergic signaling; Alzheimer's disease"	"27"	"0"	"9.8"	"9.4"	"15.2"	"16.1"	"19.1"	"9.4"	"22.8"	"2.0"	"715.2"	"726.8"	"1406.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVI7"	"ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2"	"0.000"	""	"9"	"6"	"11"	"1"	"634"	"71.3"	"8.98"	"2237.00"	"20.34"	"5"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"55210"	"ENSG00000197785"	"ATAD3A"	"B3KPB3; D2K8Q1; G3V1I6; hsa:55210; Q5SV23; Q8N275; Q96A50; Q9NVI7"	""	"1p36 copy number variation syndrome"	"1"	"0"	"10.1"	"5.5"	"11.7"	"11.5"	"7.0"	"0.0"	"20.7"	"0.0"	"197.7"	"206.5"	"371.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20674"	"Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2"	"0.000"	""	"52"	"5"	"9"	"5"	"150"	"16.8"	"6.79"	"1484.98"	"20.31"	"4"	"5"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02284"	"9377"	"ENSG00000178741"	"COX5A"	"hsa:9377; P20674; P30045; Q8TB65"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation; Arachidonate epoxygenase / epoxide hydrolase"	"8"	"0"	"35.9"	"16.5"	"53.4"	"48.4"	"50.4"	"36.8"	"68.4"	"21.4"	"1230.6"	"1213.8"	"2571.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02878"	"60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3"	"0.000"	""	"24"	"7"	"14"	"7"	"288"	"32.7"	"10.58"	"2321.48"	"20.28"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01159, Pf03868"	"6128"	"ENSG00000089009"	"RPL6"	"hsa:6128; Q02878; Q2M3Q3; Q8WW97"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"622.0"	"541.8"	"587.5"	"531.4"	"449.6"	"554.2"	"2444.4"	"11.4"	"4949.9"	"5060.7"	"7789.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0J8"	"pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2"	"0.000"	""	"4"	"3"	"7"	"3"	"1336"	"145.8"	"9.17"	"1357.09"	"20.23"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"55339"	"ENSG00000136709"	"WDR33"	"hsa:55339; Q05DP8; Q53FG9; Q587J1; Q69YF7; Q6NUQ0; Q9C0J8; Q9NUL1"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	""	"5"	"0"	"116.8"	"84.3"	"96.7"	"101.7"	"100.4"	"104.6"	"179.6"	"0.9"	"568.4"	"589.7"	"1005.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52434"	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4"	"0.000"	""	"26"	"3"	"10"	"3"	"150"	"17.1"	"4.68"	"2122.18"	"20.23"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03870"	"5437"	"ENSG00000163882"	"POLR2H"	"C9J413; C9JBJ6; C9JCU7; C9JUA8; hsa:5437; P52434; P53802; Q969R0"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of the Early Elongation Complex; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Abortive elongation of HIV-1 transcript in the absence of Tat; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"57"	"0"	"185.1"	"121.0"	"153.1"	"165.7"	"141.1"	"152.5"	"242.2"	"2.9"	"1624.6"	"1662.3"	"2736.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDI0"	"Chromodomain-helicase-DNA-binding protein 5 OS=Homo sapiens OX=9606 GN=CHD5 PE=1 SV=1"	"0.000"	""	"4"	"6"	"11"	"1"	"1954"	"222.9"	"6.15"	"1665.37"	"20.20"	"5"	"6"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"26038"	"ENSG00000116254"	"CHD5"	"hsa:26038; O75032; Q5TG89; Q7LGH2; Q8TDI0; Q9UFR9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43447"	"Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1"	"0.000"	""	"31"	"6"	"11"	"5"	"177"	"19.2"	"8.07"	"1501.63"	"20.17"	"4"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"10465"	"ENSG00000171960"	"PPIH"	"A6NNE7; hsa:10465; O43447"	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	""	"2"	"0"	"186.6"	"165.4"	"242.6"	"207.1"	"219.7"	"205.1"	"485.5"	"4.3"	"2794.7"	"2901.2"	"5229.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y230"	"RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3"	"0.000"	""	"17"	"7"	"10"	"7"	"463"	"51.1"	"5.64"	"984.69"	"20.16"	"3"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06068, Pf17856"	"10856"	"ENSG00000183207"	"RUVBL2"	"B3KQ59; E7ETE5; hsa:10856; Q6FIB9; Q6PK27; Q9Y230; Q9Y361"	"HATs acetylate histones; Telomere Extension By Telomerase"	""	"2"	"0"	"114.9"	"80.8"	"156.4"	"136.9"	"106.4"	"121.6"	"146.9"	"4.6"	"898.6"	"915.4"	"1843.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ39"	"ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1"	"0.000"	""	"8"	"4"	"7"	"3"	"737"	"82.5"	"9.17"	"1318.49"	"20.15"	"3"	"4"	""	"plasma membrane;other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08152"	"79009"	"ENSG00000107625"	"DDX50"	"hsa:79009; Q5VX37; Q8WV76; Q9BQ39; Q9BWI8"	""	""	"0"	"0"	"98.2"	"62.0"	"111.2"	"87.0"	"91.9"	"84.8"	"197.7"	"0.0"	"603.6"	"582.4"	"1193.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPT5"	"Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3"	"0.000"	""	"6"	"3"	"7"	"3"	"735"	"83.3"	"6.79"	"1224.98"	"20.14"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03081"	"23265"	"ENSG00000182473"	"EXOC7"	"B5MC69; B8XXP2; hsa:23265; Q8ND93; Q8WV91; Q96FF0; Q9H8C3; Q9H9X3; Q9HA32; Q9UPT5"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Angiopoietin-like protein 8 regulatory pathway; Ciliary landscape"	"5"	"0"	"16.6"	"12.1"	"13.1"	"14.0"	"22.2"	"27.2"	"60.5"	"11.9"	"1261.4"	"1082.3"	"2602.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13045"	"Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2"	"0.000"	""	"7"	"7"	"11"	"7"	"1269"	"144.7"	"6.05"	"2171.49"	"20.14"	"6"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf12799, Pf13855"	"2314"	"ENSG00000177731; ENSG00000284571"	"FLII"	"B4DIL0; F5H407; hsa:2314; J3QLG3; Q13045"	""	"VEGFA-VEGFR2 signaling; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"2"	"0"	"69.6"	"50.8"	"79.0"	"84.3"	"75.8"	"68.8"	"106.7"	"2.4"	"1971.5"	"2183.0"	"5045.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4L1"	"Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1"	"0.000"	""	"8"	"4"	"5"	"4"	"999"	"111.3"	"5.22"	"392.10"	"20.13"	"1"	"4"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00012"	"10525"	"ENSG00000149428; ENSG00000280682"	"HYOU1"	"A8C1Z0; B7Z909; hsa:10525; Q2I204; Q53H25; Q9Y4L1"	"XBP1(S) activates chaperone genes; Scavenging by Class F Receptors"	"VEGFA-VEGFR2 signaling"	"3"	"0"	"28.9"	"23.6"	"34.9"	"32.3"	"36.5"	"22.1"	"45.2"	"2.6"	"395.1"	"403.7"	"1122.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWB6"	"Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1"	"0.000"	""	"23"	"9"	"15"	"9"	"273"	"33.2"	"10.35"	"2531.05"	"20.12"	"8"	"7"	""	"cytosol;mitochondrion;nucleus"	""	"Pf15346"	"55082"	"ENSG00000134884"	"ARGLU1"	"B4E0Y3; hsa:55082; Q5T257; Q6IQ34; Q9NWB6"	""	""	"0"	"0"	"442.1"	"271.7"	"405.1"	"341.2"	"313.7"	"357.2"	"712.5"	"0.5"	"4225.9"	"4070.0"	"8640.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3P2"	"Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3"	"0.000"	""	"10"	"4"	"9"	"4"	"528"	"57.2"	"9.03"	"1614.10"	"20.07"	"3"	"4"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"7469"	"ENSG00000185049"	"NELFA"	"A2A2T1; hsa:7469; O95392; Q9H3P2"	"RNA Polymerase II Pre-transcription Events; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; TP53 Regulates Transcription of DNA Repair Genes"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"16"	"0"	"135.9"	"96.1"	"115.4"	"131.7"	"132.6"	"111.0"	"167.8"	"1.3"	"760.4"	"747.4"	"1610.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYH9"	"U3 small nucleolar RNA-associated protein 6 homolog OS=Homo sapiens OX=9606 GN=UTP6 PE=2 SV=2"	"0.000"	""	"12"	"4"	"7"	"4"	"597"	"70.1"	"7.28"	"1538.47"	"20.05"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08640"	"55813"	"ENSG00000108651"	"UTP6"	"hsa:55813; Q8IX96; Q96BL2; Q9NQ91; Q9NYH9"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"26.3"	"16.0"	"37.1"	"32.8"	"41.3"	"32.2"	"97.6"	"5.7"	"716.2"	"697.6"	"1546.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07197"	"Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3"	"0.000"	""	"12"	"8"	"13"	"8"	"916"	"102.4"	"4.91"	"2405.45"	"20.01"	"6"	"7"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"4741"	"ENSG00000104722"	"NEFM"	"B4DGN2; E9PBF7; hsa:4741; P07197; Q4QRK6"	""	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; Ciliary landscape"	"3"	"0"	"964.0"	"570.3"	"722.4"	"810.8"	"658.6"	"745.6"	"805.9"	"0.0"	"2481.4"	"2500.6"	"4618.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y285"	"Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3"	"0.000"	""	"11"	"4"	"7"	"4"	"508"	"57.5"	"7.80"	"1232.56"	"20.00"	"3"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf18552, Pf18553, Pf18554"	"2193"	"ENSG00000179115"	"FARSA"	"B4E363; hsa:2193; Q9NSD8; Q9Y285; Q9Y4W8"	"Cytosolic tRNA aminoacylation"	""	"1"	"0"	"82.5"	"60.4"	"88.2"	"77.7"	"79.2"	"79.1"	"169.5"	"3.6"	"803.1"	"863.3"	"1648.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15910"	"Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2"	"0.000"	""	"10"	"5"	"9"	"5"	"746"	"85.3"	"7.02"	"1785.38"	"19.97"	"4"	"5"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf11616, Pf18118, Pf18264"	"2146"	"ENSG00000106462"	"EZH2"	"B2RAQ1; B3KS30; B7Z1D6; B7Z7L6; hsa:2146; Q15755; Q15910; Q75MG3; Q92857; Q96FI6"	"HCMV Early Events; Defective pyroptosis; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA"	"Cell differentiation - expanded index; Histone modifications; Endoderm differentiation; Interactome of polycomb repressive complex 2 (PRC2) ; MECP2 and associated Rett syndrome; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"19"	"0"	"90.5"	"64.2"	"86.3"	"92.7"	"79.9"	"64.5"	"182.5"	"1.9"	"1162.7"	"1149.4"	"2478.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FV9"	"THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1"	"0.000"	""	"9"	"4"	"7"	"4"	"657"	"75.6"	"4.98"	"1660.59"	"19.96"	"3"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00531, Pf11957"	"9984"	"ENSG00000079134"	"THOC1"	"B2RBP6; hsa:9984; Q15219; Q64I72; Q64I73; Q96FV9"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"80.4"	"67.6"	"92.8"	"89.0"	"96.9"	"78.6"	"276.3"	"7.6"	"922.6"	"874.4"	"1798.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3F4"	"Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1"	"0.000"	""	"14"	"4"	"9"	"4"	"350"	"38.4"	"5.12"	"1535.43"	"19.90"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00400"	"11171"	"ENSG00000023734"	"STRAP"	"B2R5S5; B4DNJ6; hsa:11171; Q5TZT4; Q9NTK0; Q9UQC8; Q9Y3F4"	"Downregulation of TGF-beta receptor signaling"	"Epithelial to mesenchymal transition in colorectal cancer"	"2"	"0"	"238.0"	"188.9"	"224.3"	"210.2"	"219.6"	"199.8"	"355.4"	"3.7"	"1712.5"	"1651.7"	"3776.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTC0"	"Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5"	"0.000"	""	"3"	"5"	"8"	"4"	"2240"	"243.7"	"7.88"	"1281.08"	"19.90"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"11083"	"ENSG00000101191"	"DIDO1"	"A8MY65; B9EH82; E1P5I1; hsa:11083; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BTC0; Q9BW03; Q9H4G6; Q9H4G7; Q9NTU8; Q9NUM8; Q9UFB6"	""	""	"0"	"0"	"49.1"	"35.3"	"40.0"	"39.7"	"45.1"	"38.6"	"87.3"	"5.6"	"273.2"	"260.3"	"554.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13595"	"Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1"	"0.000"	""	"20"	"6"	"14"	"5"	"282"	"32.7"	"11.27"	"2001.97"	"19.86"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"29896"	"ENSG00000164548"	"TRA2A"	"B4DQI6; B4DUA9; E9PD75; hsa:29896; Q13595"	""	"Orexin receptor pathway"	"1"	"0"	"617.2"	"611.9"	"364.1"	"439.9"	"349.7"	"434.1"	"990.7"	"9.0"	"2522.5"	"2545.7"	"3947.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2U1"	"ATP-dependent DNA/RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2"	"0.000"	""	"7"	"6"	"9"	"4"	"1008"	"114.7"	"7.68"	"899.92"	"19.86"	"3"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"170506"	"ENSG00000174953"	"DHX36"	"B2RB00; hsa:170506; Q70JU3; Q8IYE5; Q9H2U1; Q9P240"	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"VEGFA-VEGFR2 signaling"	"2"	"1"	"43.8"	"35.2"	"56.4"	"55.8"	"45.9"	"52.6"	"142.5"	"40.4"	"651.8"	"560.3"	"1048.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49736"	"DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4"	"0.000"	""	"9"	"5"	"7"	"5"	"904"	"101.8"	"5.52"	"1039.13"	"19.83"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf12619, Pf14551, Pf17207, Pf17855"	"4171"	"ENSG00000073111"	"MCM2"	"hsa:4171; P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 1p36 copy number variation syndrome"	"11"	"0"	"148.7"	"107.4"	"180.0"	"162.5"	"155.1"	"175.4"	"231.1"	"4.6"	"985.7"	"1006.6"	"2654.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SW79"	"Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1"	"0.000"	""	"5"	"5"	"11"	"5"	"1584"	"175.2"	"7.11"	"1468.00"	"19.82"	"4"	"5"	""	"cytosol;cytoskeleton;other cell component"	""	"Pf00498, Pf15308"	"9859"	"ENSG00000143702; ENSG00000276725"	"CEP170"	"hsa:9859; O75058; Q5SW77; Q5SW78; Q5SW79; Q7LGA9; Q86W31; Q9UQ08; Q9UQ09"	""	"Ciliary landscape"	"1"	"0"	"81.6"	"74.5"	"88.0"	"77.9"	"85.2"	"88.6"	"172.8"	"4.4"	"702.6"	"716.8"	"1255.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15599"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2"	"0.000"	""	"16"	"4"	"8"	"4"	"337"	"37.4"	"7.93"	"1876.15"	"19.82"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf09007"	"9351"	"ENSG00000065054"	"NHERF2"	"D3DU84; D3DU85; H3BSV6; hsa:9351; O00272; O00556; Q15599; Q3KQY7"	""	""	"0"	"0"	"79.8"	"62.8"	"90.7"	"73.4"	"76.9"	"72.6"	"151.8"	"5.4"	"953.9"	"946.0"	"1591.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13148"	"TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1"	"0.000"	""	"14"	"4"	"9"	"4"	"414"	"44.7"	"6.19"	"1357.67"	"19.81"	"2"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf18694"	"23435"	"ENSG00000120948"	"TARDBP"	"A4GUK4; A4GUK5; A4GUK6; B2R629; B4DJ45; E2PU12; hsa:23435; Q13148; Q53H27; Q6FI92; Q96DJ0"	""	"MECP2 and associated Rett syndrome"	"1"	"0"	"114.6"	"83.4"	"149.1"	"124.9"	"126.9"	"131.7"	"239.8"	"6.5"	"1326.4"	"1288.3"	"2652.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYP5"	"Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3"	"0.000"	""	"3"	"5"	"10"	"5"	"2266"	"252.3"	"6.60"	"1600.46"	"19.81"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13934, Pf16687"	"25909"	"ENSG00000153207"	"AHCTF1"	"A6NGM0; A8MSG9; A8MZ86; hsa:25909; Q7Z4E3; Q8IZA4; Q8WYP5; Q96EH9; Q9Y4Q6"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"Gastric cancer network 2"	"8"	"0"	"91.3"	"65.8"	"91.6"	"89.3"	"76.1"	"76.9"	"137.1"	"4.2"	"750.4"	"723.5"	"1585.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62888"	"60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2"	"0.000"	""	"55"	"5"	"13"	"5"	"115"	"12.8"	"9.63"	"2363.35"	"19.80"	"5"	"5"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6156"	"ENSG00000156482"	"RPL30"	"B2R591; hsa:6156; P04645; P62888; Q502Z6"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"80.3"	"66.0"	"91.6"	"88.9"	"90.2"	"83.4"	"279.7"	"8.6"	"1304.7"	"1282.3"	"2315.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75962"	"Triple functional domain protein OS=Homo sapiens OX=9606 GN=TRIO PE=1 SV=2"	"0.000"	""	"3"	"5"	"9"	"5"	"3097"	"346.7"	"6.37"	"1470.91"	"19.74"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00169, Pf00435, Pf00621, Pf00650, Pf07679, Pf16609"	"7204"	"ENSG00000038382"	"TRIO"	"D3DTD1; hsa:7204; O75962; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; G alpha (q) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; DCC mediated attractive signaling"	"Microtubule cytoskeleton regulation; Neural crest cell migration during development; Neural crest cell migration in cancer"	"14"	"0"	"36.4"	"26.5"	"38.3"	"37.3"	"35.9"	"38.4"	"85.7"	"3.4"	"517.5"	"538.8"	"1035.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62979"	"Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2"	"0.000"	""	"50"	"7"	"12"	"7"	"156"	"18.0"	"9.64"	"1792.57"	"19.73"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf01599"	"6233"	"ENSG00000143947"	"RPS27A"	"hsa:6233; P02248; P02249; P02250; P14798; P62979; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7"	"Oxidative Stress Induced Senescence; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Orc1 removal from chromatin; Assembly of the pre-replicative complex; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Antigen processing: Ubiquitination & Proteasome degradation; Regulation of PTEN stability and activity; ISG15 antiviral mechanism; Downregulation of ERBB4 signaling; Regulation of PTEN localization; Regulation of PLK1 Activity at G2/M Transition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; FCERI mediated NF-kB activation; Downstream TCR signaling; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Stimuli-sensing channels; Amyloid fiber formation; Fanconi Anemia Pathway; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Activated NOTCH1 Transmits Signal to the Nucleus; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus; Peroxisomal protein import; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; IKK complex recruitment mediated by RIP1; TRAF6-mediated induction of TAK1 complex within TLR4 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; ER Quality Control Compartment (ERQC); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Circadian Clock; Regulation of signaling by CBL; Metalloprotease DUBs; Regulation of necroptotic cell death; Oncogene Induced Senescence; Cyclin D associated events in G1; APC/C:Cdc20 mediated degradation of Cyclin B; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Negative regulation of FLT3; Downregulation of ERBB2:ERBB3 signaling; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Regulation of TP53 Activity through Methylation; Regulation of BACH1 activity; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; MAP3K8 (TPL2)-dependent MAPK1/3 activation; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; Regulation of NF-kappa B signaling; Negative regulators of DDX58/IFIH1 signaling; Prevention of phagosomal-lysosomal fusion; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH1 Intracellular Domain Regulates Transcription; TICAM1-dependent activation of IRF3/IRF7; TICAM1,TRAF6-dependent induction of TAK1 complex; Glycogen synthesis; Formation of TC-NER Pre-Incision Complex; Modulation by Mtb of host immune system; activated TAK1 mediates p38 MAPK activation; IRAK2 mediated activation of TAK1 complex; SARS-CoV-1 activates/modulates innate immune responses; Alpha-protein kinase 1 signaling pathway; Ovarian tumor domain proteases; Spry regulation of FGF signaling; RAS processing; PINK1-PRKN Mediated Mitophagy; Josephin domain DUBs; Regulation of FZD by ubiquitination; Chaperone Mediated Autophagy; Formation of Incision Complex in GG-NER; Iron uptake and transport; VLDLR internalisation and degradation; Myoclonic epilepsy of Lafora; DNA Damage Recognition in GG-NER; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Negative regulation of MAPK pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); NRIF signals cell death from the nucleus; Assembly Of The HIV Virion; Regulation of innate immune responses to cytosolic DNA; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; Pexophagy; Maturation of protein E; Maturation of protein E; FLT3 signaling by CBL mutants; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"Cytoplasmic ribosomal proteins"	"201"	"0"	"833.7"	"686.4"	"843.3"	"839.8"	"717.4"	"676.6"	"1610.8"	"3.7"	"4522.7"	"4784.1"	"7191.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2D5"	"A-kinase anchor protein 2 OS=Homo sapiens OX=9606 GN=AKAP2 PE=1 SV=3"	"0.000"	""	"5"	"4"	"10"	"4"	"859"	"94.6"	"5.11"	"2312.71"	"19.71"	"4"	"4"	""	""	""	"Pf15304"	"445815"	""	"AKAP2"	"B1ALX9; B2RTU4; B3KQ00; B4DTZ2; B7ZW07; B9EJB5; Q9UG26; Q9Y2D5"	""	""	"0"	"0"	"126.8"	"91.5"	"103.6"	"115.3"	"93.8"	"103.4"	"269.2"	"6.9"	"1156.8"	"1250.2"	"1885.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16658"	"Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3"	"0.000"	""	"10"	"4"	"8"	"4"	"493"	"54.5"	"7.24"	"1513.88"	"19.68"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf06268"	"6624"	"ENSG00000075618"	"FSCN1"	"A6NI89; B2RE97; hsa:6624; Q16658; Q96IC5; Q96IH1; Q9BRF1"	"Interleukin-4 and Interleukin-13 signaling"	"VEGFA-VEGFR2 signaling; Urotensin-II-mediated signaling pathway"	"3"	"0"	"23.4"	"19.2"	"19.1"	"18.7"	"19.0"	"28.7"	"69.2"	"4.7"	"657.6"	"695.4"	"2305.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01844"	"RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1"	"0.000"	""	"9"	"5"	"12"	"5"	"656"	"68.4"	"9.33"	"1534.87"	"19.66"	"4"	"5"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00641"	"2130"	"ENSG00000182944"	"EWSR1"	"B0QYK1; hsa:2130; Q01844; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"446.8"	"378.3"	"448.9"	"369.4"	"382.3"	"407.3"	"891.6"	"0.9"	"2436.6"	"2438.0"	"3571.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UII2"	"ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1"	"0.000"	""	"25"	"5"	"14"	"5"	"106"	"12.2"	"9.35"	"2117.29"	"19.65"	"5"	"5"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04568"	"93974"	"ENSG00000130770; ENSG00000285390"	"ATP5IF1"	"hsa:93974; Q5JXL8; Q6IAQ7; Q9BSL9; Q9UII2"	""	"Electron transport chain: OXPHOS system in mitochondria"	"1"	"0"	"798.8"	"672.3"	"754.4"	"686.8"	"667.6"	"691.0"	"1549.9"	"16.5"	"5439.3"	"5731.3"	"8638.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07020"	"60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2"	"0.000"	""	"24"	"5"	"11"	"5"	"188"	"21.6"	"11.72"	"1941.14"	"19.64"	"4"	"5"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf17135"	"6141"	"ENSG00000063177"	"RPL18"	"F8VWC5; hsa:6141; Q07020; Q8WTZ6"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"267.3"	"170.8"	"264.5"	"263.2"	"234.3"	"204.8"	"848.7"	"3.2"	"2326.6"	"2258.1"	"3979.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969X6"	"U3 small nucleolar RNA-associated protein 4 homolog OS=Homo sapiens OX=9606 GN=UTP4 PE=1 SV=1"	"0.000"	""	"12"	"5"	"8"	"5"	"686"	"76.8"	"8.85"	"1190.83"	"19.64"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"84916"	"ENSG00000141076; ENSG00000262788"	"UTP4"	"hsa:84916; Q8NCD9; Q8TF14; Q969X6; Q96SP0; Q96SR9; Q96SZ9; Q96T13; Q9BWK6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"43.0"	"32.1"	"45.9"	"36.9"	"37.8"	"53.4"	"117.4"	"6.9"	"840.5"	"884.9"	"1663.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75494"	"Serine/arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1"	"0.000"	""	"23"	"5"	"8"	"4"	"262"	"31.3"	"11.27"	"1296.38"	"19.60"	"3"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10772"	"ENSG00000188529"	"SRSF10"	"A6NFM6; A6NI42; A6NIU7; B4DJP9; hsa:10772; O60572; O75494; Q5JRH9; Q5JRI0; Q5JRI2; Q5JRI3; Q5JRI4; Q96G09; Q96P17"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"3"	"1"	"333.3"	"252.5"	"312.1"	"281.5"	"294.1"	"259.8"	"459.9"	"1.4"	"1457.8"	"1364.6"	"2730.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW64"	"Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1"	"0.000"	""	"17"	"6"	"13"	"6"	"420"	"46.9"	"8.54"	"2828.09"	"19.59"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55696"	"ENSG00000086589"	"RBM22"	"A6NDM5; B4DLI9; hsa:55696; O95607; Q9NW64"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"348.2"	"316.5"	"359.8"	"342.3"	"336.0"	"304.2"	"791.1"	"1.5"	"2725.5"	"2578.8"	"4543.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18621"	"60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3"	"0.000"	""	"30"	"6"	"11"	"6"	"184"	"21.4"	"10.17"	"1742.95"	"19.57"	"5"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00237"	"6139"	"ENSG00000265681"	"RPL17"	"B2R4H3; B4E3C2; B5ME31; hsa:6139; J3QL51; P18621; Q3KQW2; Q6NZ54; Q7M4M5"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"386.3"	"287.3"	"441.4"	"388.4"	"336.2"	"354.5"	"1512.4"	"4.2"	"3322.9"	"3076.5"	"5699.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB3"	"Serine/arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2"	"0.000"	""	"8"	"6"	"12"	"6"	"904"	"102.3"	"11.84"	"3355.95"	"19.55"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf01480"	"10250"	"ENSG00000133226"	"SRRM1"	"hsa:10250; O60585; Q5VVN4; Q8IYB3"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"mRNA processing"	"7"	"0"	"276.7"	"165.7"	"228.1"	"220.2"	"197.4"	"218.1"	"471.3"	"9.7"	"3376.5"	"3346.4"	"7450.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H410"	"Kinetochore-associated protein DSN1 homolog OS=Homo sapiens OX=9606 GN=DSN1 PE=1 SV=2"	"0.000"	""	"18"	"5"	"9"	"5"	"356"	"40.0"	"7.05"	"1539.97"	"19.53"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf08202"	"79980"	"ENSG00000149636"	"DSN1"	"B4DWT2; E1P5U9; hsa:79980; Q5JW55; Q5JW56; Q9H410; Q9H8P4"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Neutrophil degranulation"	""	"7"	"0"	"36.2"	"23.0"	"50.3"	"56.7"	"44.7"	"44.1"	"83.2"	"0.1"	"1276.3"	"1337.3"	"2704.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12800"	"Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2"	"0.000"	""	"12"	"5"	"10"	"5"	"502"	"57.2"	"5.80"	"1848.70"	"19.50"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7024"	"ENSG00000135457"	"TFCP2"	"A8K5E9; hsa:7024; Q12800; Q12801; Q9UD75; Q9UD77"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"42.5"	"26.8"	"51.2"	"47.3"	"48.3"	"50.5"	"72.1"	"5.5"	"1671.1"	"1753.3"	"3469.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14185"	"Dedicator of cytokinesis protein 1 OS=Homo sapiens OX=9606 GN=DOCK1 PE=1 SV=2"	"0.000"	""	"4"	"6"	"10"	"6"	"1865"	"215.2"	"7.56"	"1217.33"	"19.43"	"4"	"5"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf06920, Pf14429, Pf16172, Pf20421, Pf20422"	"1793"	"ENSG00000150760"	"DOCK1"	"A9Z1Z5; hsa:1793; Q14185"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; DCC mediated attractive signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Regulation of actin cytoskeleton"	"14"	"0"	"56.8"	"50.3"	"82.1"	"56.2"	"73.5"	"61.4"	"149.7"	"1.2"	"2620.7"	"2636.6"	"4807.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15355"	"Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1"	"0.000"	""	"12"	"5"	"12"	"5"	"546"	"59.2"	"4.36"	"2062.47"	"19.37"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00481"	"5496"	"ENSG00000115241"	"PPM1G"	"hsa:5496; O15355"	""	"VEGFA-VEGFR2 signaling; mRNA processing"	"2"	"0"	"230.4"	"150.7"	"244.0"	"235.7"	"241.7"	"190.7"	"618.8"	"7.4"	"1966.5"	"1903.2"	"3219.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25685"	"DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4"	"0.000"	""	"16"	"5"	"11"	"5"	"340"	"38.0"	"8.63"	"1910.02"	"19.35"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf01556"	"3337"	"ENSG00000132002"	"DNAJB1"	"B4DX52; hsa:3337; P25685"	"MAPK6/MAPK4 signaling; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"Nuclear receptors meta-pathway; NRF2 pathway"	"7"	"0"	"222.8"	"152.7"	"232.5"	"233.1"	"228.6"	"255.6"	"522.2"	"2.0"	"1446.6"	"1466.0"	"2767.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61964"	"WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1"	"0.000"	""	"13"	"4"	"9"	"4"	"334"	"36.6"	"8.27"	"1208.46"	"19.35"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11091"	"ENSG00000196363"	"WDR5"	"hsa:11091; P61964; Q91VA5; Q9NWX7; Q9UGP9"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Neddylation; Formation of WDR5-containing histone-modifying complexes; RMTs methylate histone arginines; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Cardiogenesis"	"Pleural mesothelioma; Kleefstra syndrome"	"10"	"0"	"112.5"	"87.9"	"125.1"	"120.9"	"128.7"	"109.0"	"156.3"	"7.1"	"1344.5"	"1377.9"	"3186.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NV70"	"Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4"	"0.000"	""	"7"	"6"	"11"	"6"	"894"	"101.9"	"6.61"	"1854.22"	"19.32"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf09763, Pf15277"	"55763"	"ENSG00000090989"	"EXOC1"	"hsa:55763; Q504V4; Q8WUE7; Q96T15; Q9NV70; Q9NZE4"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"91.7"	"64.5"	"90.2"	"85.8"	"101.1"	"125.1"	"243.9"	"1.6"	"2527.0"	"2564.2"	"4410.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T88"	"E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1"	"0.000"	""	"6"	"4"	"7"	"4"	"793"	"89.8"	"7.56"	"1545.82"	"19.26"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00628, Pf02182, Pf12148"	"29128"	"ENSG00000276043"	"UHRF1"	"A0JBR2; A8K024; B2RBA9; hsa:29128; Q2HIX7; Q8J022; Q96T88; Q9H6S6; Q9P115; Q9P1U7"	"DNA methylation"	"Pathways affected in adenoid cystic carcinoma; Pleural mesothelioma"	"3"	"0"	"90.5"	"74.4"	"96.3"	"102.5"	"86.5"	"77.5"	"197.0"	"0.9"	"1253.8"	"1223.1"	"2968.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75396"	"Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=4"	"0.000"	""	"14"	"3"	"6"	"3"	"215"	"24.6"	"6.92"	"520.55"	"19.25"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"44.0"	"31.0"	"39.3"	"36.5"	"32.5"	"35.1"	"59.3"	"0.9"	"995.1"	"1033.7"	"2222.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15031"	"Probable leucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=LARS2 PE=1 SV=2"	"0.000"	""	"11"	"5"	"6"	"5"	"903"	"101.9"	"8.22"	"310.68"	"19.25"	"1"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00133, Pf08264"	"23395"	"ENSG00000011376"	"LARS2"	"hsa:23395; Q15031"	"Mitochondrial tRNA aminoacylation"	"Amino acid metabolism; IL-18 signaling pathway; Primary ovarian insufficiency"	"4"	"0"	"17.7"	"11.0"	"21.9"	"18.7"	"16.8"	"20.3"	"23.8"	"2.3"	"261.3"	"269.7"	"564.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16763"	"Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2"	"0.000"	""	"36"	"4"	"7"	"4"	"222"	"23.8"	"8.38"	"1286.67"	"19.22"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"27338"	"ENSG00000108106"	"UBE2S"	"hsa:27338; Q16763; Q9BTC1"	"Separation of Sister Chromatids; Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	""	"19"	"0"	"5.4"	"10.4"	"10.0"	"14.7"	"11.3"	"12.6"	"22.2"	"2.6"	"301.6"	"303.3"	"509.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19447"	"General transcription and DNA repair factor IIH helicase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1"	"0.000"	""	"7"	"4"	"8"	"4"	"782"	"89.2"	"7.23"	"948.36"	"19.22"	"2"	"4"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04851, Pf13625, Pf16203"	"2071"	"ENSG00000163161"	"ERCC3"	"hsa:2071; P19447; Q53QM0"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	"33.2"	"29.2"	"53.1"	"41.8"	"59.4"	"51.7"	"99.7"	"1.5"	"1017.7"	"1020.2"	"1826.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BJ3"	"Axin interactor, dorsalization-associated protein OS=Homo sapiens OX=9606 GN=AIDA PE=1 SV=1"	"0.000"	""	"27"	"7"	"11"	"7"	"306"	"35.0"	"6.55"	"2050.83"	"19.21"	"5"	"6"	"developmental processes;other biological processes"	"other membranes;other cell component"	"other molecular function"	"Pf08910, Pf14186"	"64853"	"ENSG00000186063"	"AIDA"	"A8K1F0; hsa:64853; Q49A81; Q5JRA4; Q658P1; Q96BJ3; Q9H9E8"	""	""	"0"	"0"	"57.9"	"47.3"	"77.7"	"57.3"	"75.8"	"60.0"	"116.7"	"6.0"	"5145.6"	"4788.0"	"5367.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95248"	"Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4"	"0.000"	""	"4"	"6"	"11"	"6"	"1868"	"208.3"	"6.90"	"2087.62"	"19.17"	"6"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"6305"	"ENSG00000100241"	"SBF1"	"A0A024R4Z9; A6PVG9; G5E933; hsa:6305; O60228; O95248; Q5JXD8; Q5PPM2; Q96GR9; Q9UGB8"	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the ER membrane"	""	"2"	"0"	"92.2"	"65.6"	"108.7"	"96.3"	"101.1"	"102.8"	"265.5"	"4.6"	"2463.4"	"2506.4"	"4058.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15145"	"Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3"	"0.000"	""	"25"	"5"	"9"	"5"	"178"	"20.5"	"8.59"	"1829.51"	"19.14"	"3"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04062"	"10094"	"ENSG00000111229"	"ARPC3"	"hsa:10094; O00554; O15145"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"166.9"	"131.1"	"148.1"	"143.7"	"153.1"	"124.0"	"262.0"	"9.3"	"2414.0"	"2317.1"	"5033.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49790"	"Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2"	"0.000"	""	"5"	"6"	"10"	"6"	"1475"	"153.8"	"8.73"	"1918.22"	"19.14"	"5"	"5"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf08604, Pf10599"	"9972"	"ENSG00000124789"	"NUP153"	"B4DIK2; E7EPX5; F6QR24; hsa:9972; P49790; Q4LE47; Q5T9I7; Q7Z743"	"Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA replication proteins; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"28"	"0"	"232.3"	"160.6"	"186.1"	"199.7"	"175.4"	"208.2"	"543.4"	"3.5"	"1708.7"	"1541.9"	"3028.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UV5"	"Ubiquitin carboxyl-terminal hydrolase 48 OS=Homo sapiens OX=9606 GN=USP48 PE=1 SV=1"	"0.000"	""	"6"	"4"	"6"	"4"	"1035"	"119.0"	"6.05"	"892.24"	"19.11"	"2"	"4"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00443"	"84196"	"ENSG00000090686"	"USP48"	"B7ZKS7; hsa:84196; Q2M3I4; Q5SZI4; Q5T3T5; Q6NX53; Q86UV5; Q8N3F6; Q96F64; Q96IQ3; Q9H5N3; Q9H5T7; Q9NUJ6; Q9NXR0"	"Ub-specific processing proteases"	""	"1"	"0"	"10.7"	"4.9"	"7.4"	"9.3"	"19.0"	"15.1"	"20.1"	"5.1"	"631.3"	"603.0"	"1453.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61221"	"ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1"	"0.000"	""	"13"	"5"	"8"	"5"	"599"	"67.3"	"8.34"	"1284.97"	"19.08"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf00005, Pf00037, Pf04068"	"6059"	"ENSG00000164163"	"ABCE1"	"hsa:6059; O88793; P61221; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66"	"Interferon alpha/beta signaling; OAS antiviral response"	""	"2"	"0"	"83.7"	"79.1"	"109.3"	"91.4"	"88.9"	"114.6"	"187.7"	"1.1"	"1395.1"	"1392.5"	"2584.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZI8"	"Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2"	"0.000"	""	"8"	"3"	"8"	"2"	"577"	"63.4"	"9.20"	"1705.43"	"19.06"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10642"	"ENSG00000159217"	"IGF2BP1"	"C9JT33; hsa:10642; Q9NZI8"	"MAPK6/MAPK4 signaling; Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; eIF5A regulation in response to inhibition of the nuclear export system"	"4"	"0"	"80.8"	"81.8"	"68.7"	"63.4"	"70.2"	"90.6"	"206.3"	"1.6"	"466.1"	"464.6"	"792.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKS6"	"Protein kinase C and casein kinase substrate in neurons protein 3 OS=Homo sapiens OX=9606 GN=PACSIN3 PE=1 SV=2"	"0.000"	""	"13"	"5"	"10"	"5"	"424"	"48.5"	"6.18"	"2185.66"	"19.06"	"5"	"5"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00611, Pf14604"	"29763"	"ENSG00000165912"	"PACSIN3"	"A6NH84; hsa:29763; Q9H331; Q9NWV9; Q9UKS6"	"Clathrin-mediated endocytosis"	""	"1"	"0"	"99.8"	"84.4"	"122.1"	"113.9"	"100.8"	"99.8"	"194.7"	"14.8"	"1684.0"	"1708.6"	"3640.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47755"	"F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3"	"0.000"	""	"28"	"4"	"7"	"4"	"286"	"32.9"	"5.85"	"1511.68"	"19.04"	"3"	"4"	"cell organization and biogenesis"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"830"	"ENSG00000198898"	"CAPZA2"	"B4DG50; hsa:830; P47755"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Sensory processing of sound by inner hair cells of the cochlea; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	""	"7"	"0"	"18.4"	"11.0"	"13.1"	"14.9"	"18.4"	"17.7"	"30.8"	"1.7"	"428.9"	"451.4"	"809.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P265"	"Disco-interacting protein 2 homolog B OS=Homo sapiens OX=9606 GN=DIP2B PE=1 SV=3"	"0.000"	""	"5"	"5"	"9"	"5"	"1576"	"171.4"	"8.09"	"1507.99"	"19.02"	"4"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity"	"Pf00501, Pf06464"	"57609"	"ENSG00000066084"	"DIP2B"	"hsa:57609; Q6B011; Q8N1L5; Q8NB38; Q9P265"	""	""	"0"	"0"	"49.4"	"34.6"	"85.7"	"80.1"	"84.3"	"79.2"	"137.4"	"5.4"	"1018.6"	"1064.7"	"2113.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH4"	"Nucleoporin Nup37 OS=Homo sapiens OX=9606 GN=NUP37 PE=1 SV=1"	"0.000"	""	"21"	"4"	"8"	"4"	"326"	"36.7"	"5.92"	"2024.57"	"19.01"	"4"	"4"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"79023"	"ENSG00000075188"	"NUP37"	"hsa:79023; Q8NFH4; Q9H644"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	""	"35"	"0"	"129.7"	"94.6"	"135.8"	"116.3"	"140.2"	"109.1"	"192.7"	"1.7"	"1356.1"	"1325.7"	"2392.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06587"	"E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2"	"0.000"	""	"15"	"4"	"6"	"2"	"406"	"42.4"	"5.62"	"925.09"	"19.00"	"2"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00097, Pf16207"	"6015"	"ENSG00000204227; ENSG00000206287; ENSG00000226788; ENSG00000228520; ENSG00000231115; ENSG00000235107"	"RING1"	"A8JZZ0; hsa:6015; Q06587; Q5JP96; Q5SQW2; Q86V19"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"Pleural mesothelioma; Notch signaling pathway"	"11"	"0"	"40.2"	"29.9"	"44.4"	"44.9"	"37.5"	"34.2"	"86.6"	"1.1"	"959.2"	"997.3"	"2302.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY8"	"Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1"	"0.000"	""	"24"	"5"	"10"	"5"	"250"	"27.4"	"8.60"	"2078.35"	"18.99"	"5"	"5"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01923"	"326625"	"ENSG00000139428"	"MMAB"	"C5HU05; hsa:326625; Q96EY8; Q9BSH0"	"Cobalamin (Cbl) metabolism; Defective MMAB causes MMA, cblB type"	"Vitamin B12 metabolism"	"3"	"0"	"103.9"	"74.9"	"125.5"	"104.6"	"118.3"	"117.8"	"165.5"	"18.2"	"2008.3"	"2095.5"	"3407.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15283"	"Ras GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=RASA2 PE=1 SV=3"	"0.000"	""	"7"	"5"	"9"	"5"	"850"	"96.6"	"7.20"	"1498.44"	"18.98"	"3"	"4"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"5922"	"ENSG00000155903"	"RASA2"	"A8K7K1; G3V0F9; hsa:5922; O00695; Q15283; Q15284; Q92594; Q99577; Q9UEQ2"	"Regulation of RAS by GAPs"	"MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Modulators of TCR signaling and T cell activation"	"5"	"0"	"23.4"	"17.0"	"22.2"	"29.2"	"46.4"	"92.2"	"286.0"	"6.8"	"1464.7"	"1304.7"	"1767.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62913"	"60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2"	"0.000"	""	"34"	"6"	"12"	"6"	"178"	"20.2"	"9.60"	"1625.34"	"18.96"	"4"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00281, Pf00673"	"6135"	"ENSG00000142676"	"RPL11"	"hsa:6135; P25121; P39026; P62913; Q8TDH2; Q9Y674"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"149.8"	"124.5"	"165.0"	"112.2"	"102.7"	"126.4"	"612.4"	"10.5"	"4005.8"	"4300.0"	"6355.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6M0"	"Deubiquitinase OTUD6B OS=Homo sapiens OX=9606 GN=OTUD6B PE=1 SV=1"	"0.000"	""	"18"	"5"	"8"	"5"	"293"	"33.8"	"6.05"	"1125.80"	"18.90"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf02338"	"51633"	"ENSG00000155100"	"OTUD6B"	"A8K6I1; B4DEY0; hsa:51633; Q8N6M0; Q9NTA4; Q9Y387"	""	"Warburg effect modulated by deubiquitinating enzymes and their substrates"	"1"	"0"	"39.1"	"22.2"	"47.7"	"37.5"	"35.3"	"41.4"	"81.6"	"6.4"	"1334.8"	"1356.6"	"2601.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62266"	"40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3"	"0.000"	""	"36"	"4"	"8"	"4"	"143"	"15.8"	"10.49"	"1229.69"	"18.87"	"2"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00164"	"6228"	"ENSG00000186468"	"RPS23"	"hsa:6228; P39028; P62266; Q6IB08"	"SARS-CoV-2 modulates host translation machinery; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"210.4"	"186.6"	"216.7"	"193.1"	"182.2"	"212.8"	"756.4"	"8.4"	"2550.6"	"2558.1"	"4325.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A72"	"Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1"	"0.000"	""	"35"	"5"	"9"	"5"	"148"	"17.3"	"6.39"	"1741.60"	"18.87"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf02792"	"55110"	"ENSG00000111196"	"MAGOHB"	"hsa:55110; Q96A72"	"Regulation of expression of SLITs and ROBOs; mRNA Splicing - Major Pathway; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	""	"6"	"0"	"55.2"	"50.6"	"68.4"	"70.4"	"69.0"	"75.7"	"333.4"	"0.7"	"1637.8"	"1645.4"	"3591.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z7A4"	"PX domain-containing protein kinase-like protein OS=Homo sapiens OX=9606 GN=PXK PE=1 SV=1"	"0.000"	""	"11"	"4"	"7"	"4"	"578"	"64.9"	"9.35"	"987.68"	"18.86"	"3"	"4"	"stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00787, Pf02205"	"54899"	"ENSG00000168297"	"PXK"	"hsa:54899; Q3BCH4; Q3BCH5; Q3BCH6; Q3BDW1; Q45L83; Q59EX3; Q6PK17; Q6ZN39; Q7Z7A4; Q96CA3; Q96R07; Q9NXB8"	""	""	"0"	"0"	"30.0"	"11.1"	"35.9"	"27.1"	"29.1"	"31.6"	"83.2"	"7.2"	"605.0"	"674.0"	"1133.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NC0"	"Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1"	"0.000"	""	"37"	"8"	"16"	"8"	"199"	"23.6"	"9.01"	"2438.55"	"18.84"	"7"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"153527"	"ENSG00000146007"	"ZMAT2"	"hsa:153527; Q96NC0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"674.2"	"512.6"	"582.2"	"568.7"	"548.3"	"577.5"	"1321.5"	"5.6"	"5067.5"	"5143.4"	"9761.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16989"	"Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4"	"0.000"	""	"17"	"4"	"10"	"2"	"372"	"40.1"	"9.77"	"1728.48"	"18.77"	"4"	"4"	"stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00313"	"8531"	"ENSG00000060138"	"YBX3"	"B2RBW6; hsa:8531; P16989; Q14121; Q969N6; Q96B76"	""	"RalA downstream regulated genes; Apoptosis-related network due to altered Notch3 in ovarian cancer"	"2"	"0"	"28.3"	"13.3"	"32.5"	"32.2"	"28.3"	"27.8"	"39.3"	"2.3"	"171.0"	"147.6"	"334.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19784"	"Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1"	"0.000"	""	"19"	"6"	"11"	"6"	"350"	"41.2"	"8.56"	"2003.50"	"18.77"	"6"	"5"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1459"	"ENSG00000070770"	"CSNK2A2"	"hsa:1459; P19784"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"Alzheimer's disease and miRNA effects; Allograft rejection; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"19"	"0"	"79.0"	"57.3"	"92.4"	"71.3"	"87.1"	"81.5"	"340.1"	"18.5"	"1749.7"	"1791.1"	"3898.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42765"	"3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2"	"0.000"	""	"12"	"5"	"11"	"5"	"397"	"41.9"	"8.09"	"1656.95"	"18.76"	"4"	"5"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"mitochondrion"	"other molecular function"	"Pf00108, Pf02803"	"10449"	"ENSG00000167315"	"ACAA2"	"hsa:10449; P42765; Q9BUT6"	"Mitochondrial Fatty Acid Beta-Oxidation"	"Fatty acid biosynthesis"	"2"	"0"	"164.2"	"133.1"	"188.7"	"166.7"	"201.7"	"176.8"	"303.2"	"4.9"	"3534.7"	"3835.2"	"6956.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63244"	"Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3"	"0.000"	""	"16"	"5"	"7"	"5"	"317"	"35.1"	"7.69"	"555.06"	"18.72"	"2"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;cytosol;mitochondrion;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;translation activity;other molecular function"	"Pf00400"	"10399"	"ENSG00000204628"	"RACK1"	"B3KTJ0; D3DWS0; hsa:10399; P25388; P63244; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47"	"Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-mediated ceramide production"	"Androgen receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; Measles virus infection; Angiotensin II receptor type 1 pathway; TROP2 regulatory signaling; Interferon type I signaling pathways"	"10"	"0"	"38.4"	"27.1"	"53.0"	"59.2"	"47.6"	"43.7"	"95.2"	"1.3"	"1023.7"	"1020.1"	"3397.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60866"	"40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1"	"0.000"	""	"36"	"6"	"11"	"6"	"119"	"13.4"	"9.94"	"1888.50"	"18.70"	"6"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00338"	"6224"	"ENSG00000008988"	"RPS20"	"B2R4F4; B4DW28; hsa:6224; P17075; P60866; Q5M8S9"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"110.6"	"77.1"	"125.9"	"107.0"	"110.1"	"100.1"	"285.9"	"2.8"	"1438.7"	"1398.4"	"2998.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IBS0"	"Twinfilin-2 OS=Homo sapiens OX=9606 GN=TWF2 PE=1 SV=2"	"0.000"	""	"13"	"3"	"7"	"3"	"349"	"39.5"	"6.84"	"1237.42"	"18.64"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"11344"	"ENSG00000247596"	"TWF2"	"hsa:11344; Q6IBS0; Q9Y3F5"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	""	"2"	"0"	"30.9"	"22.4"	"29.1"	"29.3"	"34.9"	"32.8"	"50.3"	"1.3"	"926.5"	"840.4"	"1895.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15021"	"Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3"	"0.000"	""	"4"	"4"	"7"	"4"	"1401"	"157.1"	"6.61"	"746.77"	"18.62"	"1"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12717, Pf12922"	"9918"	"ENSG00000010292"	"NCAPD2"	"D3DUR4; hsa:9918; Q15021; Q8N6U3"	"Condensation of Prometaphase Chromosomes"	""	"1"	"0"	"13.8"	"13.2"	"30.5"	"27.1"	"31.3"	"22.0"	"53.9"	"7.6"	"742.9"	"757.8"	"1894.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00429"	"Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2"	"0.000"	""	"11"	"5"	"8"	"5"	"736"	"81.8"	"6.81"	"1685.96"	"18.56"	"4"	"4"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00350, Pf01031, Pf02212"	"10059"	"ENSG00000087470"	"DNM1L"	"A8K4X9; B4DGC9; B4DSU8; G8JLD5; hsa:10059; J3KPI2; O00429; O14541; O60709; Q59GN9; Q7L6B3; Q8TBT7; Q9BWM1; Q9Y5J2"	"Apoptotic execution phase"	"Synaptic vesicle pathway; CAMKK2 pathway"	"3"	"0"	"66.9"	"38.1"	"49.8"	"58.0"	"49.6"	"49.2"	"131.5"	"2.3"	"954.9"	"1074.3"	"2023.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T58"	"Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1"	"0.000"	""	"2"	"6"	"11"	"5"	"3664"	"402.0"	"7.64"	"2402.36"	"18.51"	"6"	"5"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf07744"	"23013"	"ENSG00000065526"	"SPEN"	"hsa:23013; Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556"	"RHOBTB1 GTPase cycle"	"Notch signaling pathway"	"2"	"0"	"241.0"	"174.7"	"181.0"	"215.4"	"184.3"	"216.5"	"338.7"	"1.2"	"1476.1"	"1435.5"	"2437.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62249"	"40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2"	"0.000"	""	"34"	"5"	"13"	"5"	"146"	"16.4"	"10.21"	"2209.39"	"18.49"	"4"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00380"	"6217"	"ENSG00000105193"	"RPS16"	"B2RDD5; hsa:6217; P17008; P62249"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"263.1"	"224.5"	"280.9"	"232.0"	"291.9"	"234.5"	"606.0"	"5.4"	"2303.9"	"2440.6"	"4810.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13155"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2"	"0.000"	""	"19"	"4"	"5"	"4"	"320"	"35.3"	"8.22"	"249.56"	"18.47"	"1"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14497, Pf16780, Pf18569"	"7965"	"ENSG00000106305"	"AIMP2"	"F8W950; hsa:7965; Q13155; Q75MR1; Q96CZ5; Q9P1L2"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"Osteoclast signaling; Transcriptional activation by NRF2 in response to phytochemicals; NRF2-ARE regulation"	"5"	"0"	"59.0"	"28.5"	"70.5"	"50.8"	"63.5"	"48.9"	"95.8"	"11.9"	"1331.7"	"1356.0"	"3568.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14157"	"Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"1087"	"114.5"	"7.11"	"1768.36"	"18.42"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf12478"	"9898"	"ENSG00000143569"	"UBAP2L"	"B4E0U8; hsa:9898; Q14157; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4; Q9UGL5"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"205.6"	"162.9"	"195.0"	"220.9"	"191.2"	"198.3"	"423.7"	"0.0"	"1555.4"	"1556.3"	"2823.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76021"	"Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3"	"0.000"	""	"14"	"5"	"10"	"5"	"490"	"54.9"	"10.13"	"2103.56"	"18.38"	"5"	"5"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00687"	"26156"	"ENSG00000171490"	"RSL1D1"	"B4DJ58; D3DUG7; hsa:26156; O76021; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9"	""	""	"0"	"0"	"188.5"	"140.1"	"195.0"	"168.7"	"160.5"	"167.2"	"530.2"	"0.0"	"1470.3"	"1349.2"	"2853.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43809"	"Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1"	"0.000"	""	"33"	"8"	"14"	"8"	"227"	"26.2"	"8.82"	"3501.38"	"18.36"	"8"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13869"	"11051"	"ENSG00000167005"	"NUDT21"	"hsa:11051; O43809; Q6IB85; Q6NE84"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"734.6"	"617.0"	"608.5"	"598.2"	"554.7"	"652.5"	"1138.4"	"15.2"	"4045.3"	"4225.7"	"8440.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14978"	"Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2"	"0.000"	""	"9"	"8"	"14"	"8"	"699"	"73.6"	"9.47"	"2615.88"	"18.35"	"8"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05022"	"9221"	"ENSG00000166197"	"NOLC1"	"hsa:9221; Q14978; Q15030; Q5VV70; Q9BUV3"	""	""	"0"	"0"	"565.7"	"401.7"	"513.8"	"487.7"	"429.4"	"513.7"	"850.9"	"1.3"	"4124.2"	"4244.1"	"8336.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28340"	"DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2"	"0.000"	""	"8"	"6"	"10"	"6"	"1107"	"123.6"	"7.03"	"2187.37"	"18.35"	"5"	"5"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260"	"5424"	"ENSG00000062822"	"POLD1"	"hsa:5424; P28340; Q8NER3; Q96H98"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Cytosolic iron-sulfur cluster assembly; Polymerase switching on the C-strand of the telomere; Polymerase switching"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Progeria-associated lipodystrophy; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"27"	"0"	"63.4"	"52.4"	"70.9"	"56.2"	"57.6"	"39.7"	"109.2"	"3.6"	"940.9"	"1011.1"	"1998.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0G5"	"Nuclear speckle splicing regulatory protein 1 OS=Homo sapiens OX=9606 GN=NSRP1 PE=1 SV=1"	"0.000"	""	"10"	"5"	"8"	"5"	"558"	"66.4"	"8.84"	"1353.11"	"18.30"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09745, Pf20427"	"84081"	"ENSG00000126653"	"NSRP1"	"hsa:84081; Q6FI71; Q9H0G5"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"116.4"	"83.7"	"114.9"	"124.3"	"106.8"	"111.0"	"249.4"	"3.7"	"1377.3"	"1248.6"	"2673.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B4"	"Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1"	"0.000"	""	"43"	"5"	"11"	"5"	"125"	"14.6"	"9.38"	"1229.40"	"18.23"	"3"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"51639"	"ENSG00000115128"	"SF3B6"	"hsa:51639; Q53TM1; Q9Y3B4"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	""	"2"	"0"	"176.6"	"77.4"	"194.2"	"183.1"	"144.9"	"140.7"	"295.5"	"7.0"	"1938.7"	"1837.0"	"4130.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49821"	"NADH dehydrogenase [ubiquinone] flavoprotein 1, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV1 PE=1 SV=4"	"0.000"	""	"13"	"5"	"10"	"5"	"464"	"50.8"	"8.21"	"1888.80"	"18.23"	"5"	"5"	"other metabolic processes;transport"	"other membranes;cytosol;mitochondrion"	"transporter activity;other molecular function"	"Pf01512, Pf10531, Pf10589"	"4723"	"ENSG00000167792"	"NDUFV1"	"hsa:4723; O60924; O60940; P49821; Q16104; Q6IBR3; Q96BF8; Q96HS7"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"40.0"	"30.0"	"41.5"	"43.2"	"48.2"	"49.0"	"77.7"	"3.1"	"1520.2"	"1691.7"	"3445.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C57"	"Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2"	"0.000"	""	"21"	"4"	"9"	"4"	"262"	"28.2"	"9.42"	"2343.76"	"18.22"	"4"	"3"	"cell-cell signaling;signal transduction;other biological processes"	"nucleus"	""	""	"64897"	"ENSG00000157895"	"CUSTOS"	"hsa:64897; Q53HF0; Q96C57; Q9H9Z7"	""	""	"0"	"0"	"99.2"	"81.7"	"100.3"	"79.2"	"96.4"	"91.7"	"212.2"	"5.9"	"1312.3"	"1371.8"	"2347.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15126"	"Phosphomevalonate kinase OS=Homo sapiens OX=9606 GN=PMVK PE=1 SV=3"	"0.000"	""	"40"	"7"	"12"	"7"	"192"	"22.0"	"5.73"	"2465.41"	"18.17"	"6"	"6"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf04275"	"10654"	"ENSG00000163344"	"PMVK"	"hsa:10654; Q15126; Q5TZW9"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"Cholesterol biosynthesis pathway; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"8"	"0"	"45.8"	"36.7"	"66.5"	"56.6"	"73.6"	"77.2"	"135.4"	"9.9"	"3206.6"	"3353.5"	"5613.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92599"	"Septin-8 OS=Homo sapiens OX=9606 GN=SEPTIN8 PE=1 SV=4"	"0.000"	""	"8"	"4"	"11"	"1"	"483"	"55.7"	"6.28"	"1699.51"	"18.14"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00735"	"23176"	"ENSG00000164402"	"SEPTIN8"	"A6NC65; A6NKP6; F6W7K9; hsa:23176; Q8IX36; Q8IX37; Q92599; Q9BVB3"	""	"22q11.2 copy number variation syndrome"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P5R6"	"60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2"	"0.000"	""	"46"	"4"	"9"	"3"	"122"	"14.6"	"9.38"	"1196.16"	"18.09"	"3"	"4"	"protein metabolism;other metabolic processes"	"translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01776"	"200916"	"ENSG00000163584"	"RPL22L1"	"hsa:200916; Q32Q77; Q6P5R6"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	""	"13"	"0"	"12.5"	"11.9"	"17.7"	"12.6"	"12.9"	"14.4"	"47.0"	"8.3"	"509.0"	"536.2"	"1134.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43670"	"BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1"	"0.000"	""	"16"	"6"	"8"	"6"	"478"	"50.7"	"9.10"	"1191.76"	"18.04"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	""	"7756"	"ENSG00000010244"	"ZNF207"	"A8K6Y6; E1P660; E1P661; E1P662; hsa:7756; O43670; Q53XS9; Q96HW5; Q9BUQ7"	""	""	"0"	"0"	"102.4"	"80.2"	"113.7"	"88.7"	"65.4"	"65.7"	"246.3"	"7.5"	"1832.9"	"1808.1"	"3992.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15287"	"RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1"	"0.000"	""	"13"	"4"	"11"	"4"	"305"	"34.2"	"11.84"	"2000.94"	"18.00"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10921"	"ENSG00000205937"	"RNPS1"	"A8K1P0; B4DDU8; B4DZU7; B7ZA17; hsa:10921; O75308; Q15287; Q32P25; Q8WY42; Q9NYG3"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"mRNA processing"	"7"	"0"	"283.1"	"205.2"	"264.0"	"263.8"	"228.6"	"264.4"	"965.3"	"2.4"	"1954.2"	"1968.2"	"3441.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15691"	"Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3"	"0.000"	""	"25"	"5"	"6"	"5"	"268"	"30.0"	"5.14"	"706.63"	"17.98"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22919"	"ENSG00000101367"	"MAPRE1"	"B2R6I7; E1P5M8; hsa:22919; Q15691; Q3KQS8"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Anchoring of the basal body to the plasma membrane; The role of GTSE1 in G2/M progression after G2 checkpoint; Recruitment of NuMA to mitotic centrosomes; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Microtubule cytoskeleton regulation"	"15"	"0"	"123.9"	"110.5"	"131.7"	"126.2"	"120.8"	"130.2"	"205.4"	"0.0"	"1392.6"	"1507.2"	"4591.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHD1"	"Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2"	"0.000"	""	"15"	"4"	"8"	"4"	"332"	"37.5"	"7.87"	"1197.41"	"17.97"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf04968, Pf04969"	"26973"	"ENSG00000110172; ENSG00000285023"	"CHORDC1"	"B2R6P8; hsa:26973; Q6IN49; Q8WVL9; Q9H3D6; Q9UHD1"	""	""	"0"	"0"	"52.9"	"35.5"	"68.2"	"60.2"	"62.7"	"60.2"	"133.7"	"1.8"	"1113.8"	"1165.4"	"3566.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78332"	"RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5"	"0.000"	""	"5"	"5"	"10"	"5"	"1123"	"128.6"	"6.32"	"1892.94"	"17.95"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf17780"	"10180"	"ENSG00000004534"	"RBM6"	"B4E0G6; hsa:10180; O60549; O75524; P78332; Q86SS3"	""	""	"0"	"0"	"165.3"	"141.6"	"177.3"	"186.5"	"165.4"	"149.4"	"388.6"	"0.7"	"1345.0"	"1378.4"	"2347.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78406"	"mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1"	"0.000"	""	"17"	"5"	"9"	"5"	"368"	"40.9"	"7.83"	"2208.76"	"17.95"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00400"	"8480"	"ENSG00000101146"	"RAE1"	"A8K882; hsa:8480; O15306; P78406; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Transcriptional regulation by small RNAs; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"IL-18 signaling pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"30"	"0"	"489.8"	"317.4"	"447.5"	"441.0"	"430.1"	"428.3"	"661.8"	"0.0"	"2897.3"	"2712.4"	"5404.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVV9"	"Heterogeneous nuclear ribonucleoprotein L-like OS=Homo sapiens OX=9606 GN=HNRNPLL PE=1 SV=1"	"0.000"	""	"9"	"4"	"10"	"3"	"542"	"60.0"	"7.72"	"1603.85"	"17.93"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"92906"	"ENSG00000143889"	"HNRNPLL"	"hsa:92906; Q53T80; Q5JB51; Q5JB52; Q659B9; Q8IVH5; Q8IVH6; Q8WVV9; Q96HR5"	""	""	"0"	"0"	"20.6"	"15.2"	"24.3"	"24.0"	"22.6"	"23.4"	"58.5"	"2.5"	"531.2"	"493.8"	"1145.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36542"	"ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1"	"0.000"	""	"18"	"5"	"10"	"5"	"298"	"33.0"	"9.22"	"1042.23"	"17.93"	"4"	"5"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00231"	"509"	"ENSG00000165629"	"ATP5F1C"	"A8KA31; hsa:509; P36542; Q5VYP3; Q6I9V2; Q96AS8"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria"	"3"	"0"	"43.5"	"36.8"	"43.7"	"37.2"	"32.6"	"44.6"	"106.4"	"2.4"	"1235.7"	"1316.4"	"2738.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75689"	"Arf-GAP with dual PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ADAP1 PE=1 SV=2"	"0.000"	""	"23"	"7"	"12"	"6"	"374"	"43.4"	"8.97"	"2264.90"	"17.92"	"7"	"5"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"11033"	"ENSG00000105963"	"ADAP1"	"A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4; hsa:11033; O75689"	"Nuclear signaling by ERBB4"	""	"1"	"1"	"114.5"	"98.0"	"145.2"	"128.3"	"141.6"	"140.6"	"323.8"	"11.9"	"3459.3"	"3432.9"	"4842.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61313"	"60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2"	"0.000"	""	"22"	"5"	"12"	"5"	"204"	"24.1"	"11.62"	"2175.76"	"17.88"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00827"	"6138"	"ENSG00000174748"	"RPL15"	"hsa:6138; P39030; P41051; P61313; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44; Q9H2E5"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"122.6"	"116.6"	"122.0"	"104.8"	"97.2"	"115.5"	"673.6"	"3.5"	"1955.6"	"1954.8"	"3094.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12789"	"General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4"	"0.000"	""	"4"	"6"	"8"	"6"	"2109"	"238.7"	"7.30"	"1861.25"	"17.87"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04182"	"2975"	"ENSG00000077235"	"GTF3C1"	"B2RP21; hsa:2975; Q12789; Q12838; Q6DKN9; Q9Y4W9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	"31.8"	"27.1"	"36.6"	"32.0"	"36.7"	"38.1"	"90.2"	"6.2"	"737.9"	"720.0"	"1718.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTK5"	"Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2"	"0.000"	""	"17"	"6"	"10"	"6"	"396"	"44.7"	"7.81"	"2132.28"	"17.82"	"5"	"5"	"other metabolic processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;other molecular function"	"Pf01926, Pf06071"	"29789"	"ENSG00000138430"	"OLA1"	"D7EHM2; hsa:29789; Q5BJD7; Q8NCI8; Q96CU1; Q96SV2; Q9NTK5; Q9P1D3; Q9UNY9; Q9Y6G4"	"Platelet degranulation"	""	"1"	"0"	"280.9"	"213.7"	"267.8"	"258.7"	"308.5"	"272.7"	"468.7"	"14.4"	"3168.0"	"3075.6"	"6187.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02809"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2"	"0.000"	""	"9"	"4"	"8"	"4"	"727"	"83.5"	"6.95"	"1643.11"	"17.81"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03171"	"5351"	"ENSG00000083444"	"PLOD1"	"B4DR87; hsa:5351; Q02809; Q96AV9; Q9H132"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	"47.5"	"25.6"	"50.1"	"47.4"	"42.4"	"59.9"	"109.9"	"7.3"	"791.0"	"770.5"	"1556.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48729"	"Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2"	"0.000"	""	"17"	"4"	"6"	"4"	"337"	"38.9"	"9.57"	"856.61"	"17.77"	"2"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1452"	"ENSG00000113712"	"CSNK1A1"	"D3DQG0; D3DQG1; hsa:1452; P48729; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Activation of SMO; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein"	"Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Complement system; Wnt signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Chromosomal and microsatellite instability in colorectal cancer ; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Alzheimer's disease; DYRK1A involvement regarding cell proliferation in brain development"	"32"	"0"	"26.1"	"29.9"	"50.3"	"37.2"	"43.6"	"48.3"	"98.3"	"7.7"	"632.8"	"631.2"	"1626.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UB35"	"Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1"	"0.000"	""	"4"	"3"	"8"	"3"	"978"	"105.7"	"8.06"	"1753.14"	"17.76"	"3"	"3"	"other metabolic processes;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00763, Pf01268, Pf02882"	"25902"	"ENSG00000120254"	"MTHFD1L"	"hsa:25902; Q2TBF3; Q6UB35; Q8WVW0; Q96HG8; Q9H789; Q9UFU8"	"Metabolism of folate and pterines"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"3"	"0"	"58.8"	"40.6"	"59.6"	"64.0"	"59.3"	"56.4"	"91.2"	"0.0"	"985.1"	"992.2"	"2070.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13111"	"Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3"	"0.000"	""	"7"	"5"	"9"	"5"	"956"	"106.8"	"5.94"	"2277.63"	"17.76"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf11600, Pf12253, Pf15539, Pf15557"	"10036"	"ENSG00000167670"	"CHAF1A"	"hsa:10036; Q13111; Q6NXG5; Q7Z7K3; Q9UJY8"	""	"Nanoparticle triggered autophagic cell death"	"1"	"0"	"86.4"	"62.1"	"111.9"	"95.6"	"107.9"	"76.4"	"201.8"	"1.9"	"1781.3"	"1720.5"	"3665.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14980"	"Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1"	"0.000"	""	"5"	"4"	"9"	"4"	"1071"	"123.3"	"6.06"	"1608.15"	"17.66"	"3"	"4"	"other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03810, Pf08389, Pf08767, Pf18777, Pf18784, Pf18787"	"7514"	"ENSG00000082898"	"XPO1"	"A6NL14; A8K1K5; D6W5E2; hsa:7514; O14980; Q63HP8; Q68CP3; Q99433"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; MAPK6/MAPK4 signaling; NPAS4 regulates expression of target genes; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Heme signaling; Deactivation of the beta-catenin transactivating complex; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Downregulation of TGF-beta receptor signaling; HuR (ELAVL1) binds and stabilizes mRNA; Cyclin A/B1/B2 associated events during G2/M transition"	"eIF5A regulation in response to inhibition of the nuclear export system; 22q11.2 copy number variation syndrome"	"18"	"0"	"24.5"	"12.4"	"23.4"	"14.3"	"17.6"	"13.6"	"30.2"	"4.3"	"467.2"	"519.1"	"1129.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15226"	"NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2"	"0.000"	""	"11"	"6"	"10"	"6"	"690"	"77.6"	"8.79"	"2080.27"	"17.66"	"5"	"5"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01424, Pf01585"	"55922"	"ENSG00000186416"	"NKRF"	"G3V1N1; hsa:55922; O15226; Q4VC41; Q9UJ91"	""	"Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex; Network map of SARS-CoV-2 signaling pathway"	"2"	"0"	"318.2"	"213.8"	"251.4"	"262.0"	"242.6"	"244.1"	"556.4"	"4.7"	"1512.5"	"1476.0"	"2518.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94901"	"SUN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUN1 PE=1 SV=3"	"0.000"	""	"6"	"4"	"8"	"4"	"812"	"90.0"	"7.08"	"1686.27"	"17.66"	"4"	"4"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"36.5"	"18.6"	"37.1"	"24.8"	"33.8"	"30.8"	"57.7"	"3.0"	"692.6"	"705.8"	"1587.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4A5"	"Transformation/transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3"	"0.000"	""	"2"	"6"	"11"	"6"	"3859"	"437.3"	"8.19"	"1965.66"	"17.65"	"6"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00454, Pf02259, Pf20175, Pf20206"	"8295"	"ENSG00000196367"	"TRRAP"	"A4D265; hsa:8295; O75218; Q9Y4A5; Q9Y631; Q9Y6H4"	"Ub-specific processing proteases; Formation of the beta-catenin:TCF transactivating complex; HATs acetylate histones"	"Rett syndrome causing genes"	"4"	"0"	"103.2"	"90.5"	"104.1"	"113.5"	"103.4"	"68.2"	"114.9"	"12.7"	"532.0"	"588.0"	"1085.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YN2"	"CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2"	"0.000"	""	"13"	"5"	"9"	"5"	"538"	"60.6"	"7.24"	"1879.80"	"17.54"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"enzyme regulator activity"	"Pf04676, Pf04677"	"55280"	"ENSG00000095485"	"CWF19L1"	"B4DHX1; D3DR66; hsa:55280; Q5W0I3; Q69YN2; Q96HC3; Q9H865; Q9NV13"	""	""	"0"	"0"	"40.7"	"31.1"	"56.8"	"43.7"	"57.7"	"40.0"	"79.2"	"4.6"	"819.6"	"802.7"	"1543.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00505"	"Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"1"	"521"	"57.8"	"4.94"	"537.09"	"17.52"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3839"	"ENSG00000102753"	"KPNA3"	"hsa:3839; O00191; O00505; O43195; Q5JVM9; Q8IYQ9; Q96AA7"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	""	"2"	"0"	"2.0"	"4.2"	"8.9"	"7.9"	"7.1"	"5.0"	"20.6"	"0.0"	"320.8"	"320.8"	"815.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQP7"	"Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1"	"0.000"	""	"17"	"4"	"6"	"4"	"344"	"39.4"	"7.68"	"802.26"	"17.52"	"2"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf12705"	"92667"	"ENSG00000125871"	"MGME1"	"B2RDG5; D3DW29; hsa:92667; Q96SW3; Q9BQP7"	""	"Primary ovarian insufficiency"	"1"	"0"	"18.9"	"25.5"	"31.1"	"21.1"	"23.6"	"21.0"	"57.9"	"2.0"	"745.3"	"715.3"	"1639.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBU8"	"Mortality factor 4-like protein 1 OS=Homo sapiens OX=9606 GN=MORF4L1 PE=1 SV=2"	"0.000"	""	"12"	"4"	"7"	"4"	"362"	"41.4"	"9.28"	"1527.64"	"17.49"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05712, Pf11717"	"10933"	"ENSG00000185787"	"MORF4L1"	"B4DKN6; B7Z6R1; D3DW88; hsa:10933; O95899; Q5QTS1; Q6NVX8; Q86YT7; Q9HBP6; Q9NSW5; Q9UBU8"	"HATs acetylate histones"	"Pathways affected in adenoid cystic carcinoma"	"2"	"0"	"96.1"	"78.3"	"91.3"	"93.2"	"100.9"	"104.6"	"249.4"	"5.8"	"1430.9"	"1466.3"	"3033.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05397"	"Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2"	"0.000"	""	"6"	"5"	"8"	"5"	"1052"	"119.2"	"6.62"	"1333.47"	"17.39"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00373, Pf03623, Pf07714, Pf18038"	"5747"	"ENSG00000169398"	"PTK2"	"B4E2N6; F5H4S4; hsa:5747; J3QT16; Q05397; Q14291; Q8IYN9; Q9UD85"	"RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; DCC mediated attractive signaling; VEGFA-VEGFR2 Pathway; EPHB-mediated forward signaling; Signal regulatory protein family interactions; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Apoptotic cleavage of cellular proteins"	"Androgen receptor signaling pathway; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Corticotropin-releasing hormone signaling pathway; Alpha 6 beta 4 signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Overview of nanoparticle effects; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Hippo-Merlin signaling dysregulation; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Small cell lung cancer; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Pleural mesothelioma; Regulation of actin cytoskeleton; 2q13 copy number variation syndrome; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"48"	"0"	"130.1"	"91.3"	"138.5"	"112.5"	"137.5"	"177.9"	"438.1"	"0.0"	"2558.4"	"2498.5"	"3677.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60828"	"Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1"	"0.000"	""	"23"	"4"	"8"	"4"	"265"	"30.5"	"6.33"	"2016.66"	"17.36"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"10084"	"ENSG00000102103"	"PQBP1"	"C9JQA1; hsa:10084; O60828; Q4VY25; Q4VY26; Q4VY27; Q4VY29; Q4VY30; Q4VY34; Q4VY35; Q4VY36; Q4VY37; Q4VY38; Q9GZP2; Q9GZU4; Q9GZZ4"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"255.9"	"188.2"	"214.7"	"205.5"	"203.6"	"217.6"	"464.9"	"3.3"	"1808.2"	"1857.3"	"3396.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0C8"	"Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1"	"0.000"	""	"12"	"5"	"8"	"5"	"392"	"42.9"	"7.09"	"1190.49"	"17.29"	"3"	"5"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00481"	"80895"	"ENSG00000132323"	"ILKAP"	"B3KM39; hsa:80895; Q9H0C8"	""	"2q37 copy number variation syndrome"	"1"	"0"	"69.9"	"54.9"	"76.2"	"72.6"	"64.0"	"63.1"	"105.7"	"3.6"	"2267.2"	"2270.4"	"3895.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49454"	"Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3"	"0.000"	""	"3"	"7"	"13"	"7"	"3114"	"357.3"	"5.10"	"2412.34"	"17.26"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10473, Pf10481, Pf10490"	"1063"	"ENSG00000117724"	"CENPF"	"hsa:1063; P49454; Q13171; Q13246; Q5VVM7"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Polo-like kinase mediated events"	"Gastric cancer network 1; Ciliopathies"	"9"	"0"	"38.8"	"25.9"	"48.8"	"35.3"	"30.1"	"38.9"	"107.6"	"2.8"	"452.3"	"424.0"	"779.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UXN9"	"WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1"	"0.000"	""	"14"	"5"	"7"	"5"	"313"	"35.1"	"7.69"	"982.30"	"17.25"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"80335"	"ENSG00000164091"	"WDR82"	"A8K5R5; hsa:80335; Q6UXN9; Q8TEB2"	"Formation of WDR5-containing histone-modifying complexes"	""	"1"	"0"	"196.2"	"153.9"	"169.5"	"184.1"	"183.1"	"149.8"	"354.0"	"2.7"	"2217.8"	"2321.4"	"4994.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PKG0"	"La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2"	"0.000"	""	"5"	"5"	"9"	"5"	"1096"	"123.4"	"8.82"	"1533.68"	"17.23"	"4"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf05383"	"23367"	"ENSG00000155506"	"LARP1"	"hsa:23367; O94836; Q6PKG0; Q8N4M2; Q8NB73; Q9UFD7"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Network map of SARS-CoV-2 signaling pathway"	"4"	"0"	"199.8"	"142.1"	"209.2"	"219.5"	"215.9"	"221.0"	"436.5"	"1.9"	"1779.8"	"1705.9"	"3521.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00308"	"NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens OX=9606 GN=WWP2 PE=1 SV=2"	"0.000"	""	"4"	"3"	"7"	"2"	"870"	"98.9"	"7.12"	"1359.33"	"17.16"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf00632"	"11060"	"ENSG00000198373"	"WWP2"	"A6NEP1; B2R706; B4DTL5; F5H213; H3BRF3; hsa:11060; I3RSG8; O00308; Q6ZTQ5; Q96CZ2; Q9BWN6"	"RHOQ GTPase cycle; Regulation of PTEN stability and activity; RHOJ GTPase cycle; NOTCH3 Activation and Transmission of Signal to the Nucleus; RHOU GTPase cycle"	""	"5"	"0"	"7.1"	"5.5"	"11.3"	"7.7"	"12.4"	"7.3"	"21.9"	"7.3"	"218.0"	"227.3"	"532.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78368"	"Casein kinase I isoform gamma-2 OS=Homo sapiens OX=9606 GN=CSNK1G2 PE=1 SV=1"	"0.000"	""	"13"	"4"	"7"	"1"	"415"	"47.4"	"9.06"	"601.66"	"17.13"	"1"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12605"	"1455"	"ENSG00000133275"	"CSNK1G2"	"B5BU42; hsa:1455; O00704; P78368; Q8WUB1"	"Sphingolipid de novo biosynthesis; Disassembly of the destruction complex and recruitment of AXIN to the membrane"	"Hedgehog signaling pathway"	"3"	"0"	"6.5"	"4.0"	"11.4"	"7.5"	"8.5"	"10.0"	"17.0"	"2.8"	"109.7"	"98.5"	"221.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99549"	"M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2"	"0.000"	""	"4"	"3"	"8"	"3"	"860"	"97.1"	"6.06"	"2032.89"	"17.12"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf12796"	"54737"	"ENSG00000196199"	"MPHOSPH8"	"B7Z6F9; hsa:54737; Q5JPE5; Q5JTQ0; Q86TK3; Q96MK4; Q99549; Q9BTP1"	""	""	"0"	"0"	"96.1"	"66.1"	"74.4"	"78.9"	"71.5"	"84.0"	"156.2"	"6.4"	"1254.9"	"1179.5"	"2666.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y376"	"Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39 PE=1 SV=1"	"0.000"	""	"12"	"4"	"7"	"4"	"341"	"39.8"	"6.89"	"849.64"	"17.08"	"2"	"4"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08569"	"51719"	"ENSG00000135932"	"CAB39"	"A8K8L7; hsa:51719; Q9Y376"	"Neutrophil degranulation; Energy dependent regulation of mTOR by LKB1-AMPK"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias"	"6"	"0"	"37.0"	"22.6"	"42.5"	"32.9"	"45.7"	"64.5"	"167.5"	"5.4"	"1488.7"	"1551.3"	"3356.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75717"	"WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"6"	"2"	"1129"	"125.9"	"5.62"	"1738.86"	"17.08"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12341, Pf12894"	"11169"	"ENSG00000198554"	"WDHD1"	"C9JW18; F6W0U7; hsa:11169; O75717"	""	"Mesodermal commitment pathway"	"1"	"0"	"136.9"	"102.6"	"142.4"	"129.3"	"110.9"	"125.4"	"175.9"	"4.3"	"1221.5"	"1236.9"	"2389.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14152"	"Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1"	"0.000"	""	"4"	"5"	"9"	"5"	"1382"	"166.5"	"6.79"	"1419.16"	"17.02"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01399"	"8661"	"ENSG00000107581"	"EIF3A"	"B1AMV5; B4DYS1; F5H335; hsa:8661; O00653; Q14152; Q15778"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"153.9"	"130.8"	"176.6"	"147.7"	"131.3"	"136.7"	"214.7"	"1.8"	"1054.3"	"1053.5"	"2923.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGP8"	"Translocation protein SEC63 homolog OS=Homo sapiens OX=9606 GN=SEC63 PE=1 SV=2"	"0.000"	""	"7"	"4"	"7"	"4"	"760"	"87.9"	"5.31"	"1432.20"	"17.01"	"3"	"4"	"other metabolic processes;transport;developmental processes"	"other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00226, Pf02889"	"11231"	"ENSG00000025796"	"SEC63"	"hsa:11231; O95380; Q5THN4; Q86VS9; Q8IWL0; Q9NTE0; Q9UGP8"	""	""	"0"	"0"	"25.7"	"17.4"	"26.8"	"30.8"	"25.6"	"29.3"	"56.2"	"0.0"	"747.8"	"815.9"	"2037.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96000"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3"	"0.000"	""	"23"	"4"	"8"	"4"	"172"	"20.8"	"8.48"	"1729.10"	"16.98"	"4"	"4"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10249"	"4716"	"ENSG00000140990"	"NDUFB10"	"hsa:4716; O96000; Q96II6"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Modulators of TCR signaling and T cell activation; Oxidative phosphorylation"	"6"	"0"	"44.1"	"30.8"	"48.3"	"40.5"	"40.6"	"39.8"	"109.8"	"4.4"	"1077.0"	"1051.0"	"1934.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Z4"	"Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2"	"0.000"	""	"10"	"3"	"8"	"3"	"477"	"53.2"	"8.98"	"1679.59"	"16.94"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00579"	"51067"	"ENSG00000139131"	"YARS2"	"D3DUW8; hsa:51067; Q9H817; Q9Y2Z4"	"Mitochondrial tRNA aminoacylation"	"Orexin receptor pathway"	"2"	"0"	"37.3"	"36.9"	"42.6"	"39.6"	"48.9"	"42.1"	"58.6"	"1.9"	"315.1"	"288.0"	"592.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWS9"	"Chitinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHID1 PE=1 SV=1"	"0.000"	""	"11"	"4"	"8"	"4"	"393"	"44.9"	"8.63"	"1295.09"	"16.90"	"4"	"3"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00704"	"66005"	"ENSG00000177830"	"CHID1"	"B3KWB0; hsa:66005; Q8NBM9; Q96CZ3; Q96S93; Q96SK0; Q9BWS9; Q9BY52"	"Platelet degranulation"	""	"1"	"0"	"131.2"	"131.1"	"123.7"	"116.7"	"108.7"	"132.5"	"244.4"	"11.6"	"1730.0"	"1742.5"	"4057.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H857"	"5'-nucleotidase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NT5DC2 PE=1 SV=1"	"0.000"	""	"11"	"4"	"8"	"4"	"520"	"60.7"	"6.77"	"1743.45"	"16.89"	"4"	"4"	""	""	"other molecular function"	"Pf05761"	"64943"	"ENSG00000168268"	"NT5DC2"	"C9JTZ6; E9PAL9; hsa:64943; O95888; Q96C80; Q9H857; Q9H9Z8"	""	""	"0"	"0"	"62.0"	"31.8"	"83.3"	"61.4"	"69.3"	"71.1"	"139.0"	"1.7"	"741.2"	"718.3"	"1443.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62263"	"40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3"	"0.000"	""	"28"	"3"	"7"	"3"	"151"	"16.3"	"10.05"	"1094.42"	"16.84"	"2"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"6208"	"ENSG00000164587"	"RPS14"	"B2R5G5; D3DQG5; hsa:6208; P06366; P62263; Q5BJI0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"194.1"	"154.7"	"164.1"	"166.0"	"159.3"	"152.8"	"296.3"	"3.5"	"872.9"	"814.5"	"1506.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2G2"	"STE20-like serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1"	"0.000"	""	"5"	"4"	"7"	"4"	"1235"	"142.6"	"5.15"	"1132.81"	"16.82"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12474"	"9748"	"ENSG00000065613"	"SLK"	"D3DRA0; D3DRA1; hsa:9748; O00211; Q6P1Z4; Q86WU7; Q86WW1; Q92603; Q9H2G2; Q9NQL0; Q9NQL1"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"TAR syndrome"	"4"	"0"	"65.2"	"48.2"	"76.7"	"83.0"	"76.7"	"71.1"	"148.8"	"1.7"	"1402.3"	"1449.1"	"3197.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75153"	"Clustered mitochondria protein homolog OS=Homo sapiens OX=9606 GN=CLUH PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1309"	"146.6"	"6.13"	"692.46"	"16.81"	"2"	"3"	"cell organization and biogenesis"	"other cell component"	"nucleic acid binding activity"	"Pf12807, Pf13236, Pf13374, Pf13424, Pf15044"	"23277"	"ENSG00000132361"	"CLUH"	"hsa:23277; O75153; Q6AHY2; Q6P3X7; Q6ZUG8; Q8N4U7; Q9BTA3; Q9H979"	""	"Translation factors"	"1"	"0"	"18.2"	"10.2"	"27.7"	"17.7"	"27.7"	"21.2"	"29.8"	"0.0"	"510.6"	"534.0"	"1224.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92769"	"Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2"	"0.000"	""	"15"	"4"	"7"	"1"	"488"	"55.3"	"5.91"	"1276.98"	"16.81"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3066"	"ENSG00000196591"	"HDAC2"	"B3KRS5; B4DL58; E1P561; hsa:3066; Q5SRI8; Q5SZ86; Q8NEH4; Q92769"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; NoRC negatively regulates rRNA expression; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation; Potential therapeutics for SARS; SUMOylation of chromatin organization proteins; HDACs deacetylate histones; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; EGR2 and SOX10-mediated initiation of Schwann cell myelination; MECP2 regulates neuronal receptors and channels"	"Cell cycle; Neural crest differentiation; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; Ethanol effects on histone modifications; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; 7q11.23 copy number variation syndrome; SARS-CoV-2 innate immunity evasion and cell-specific immune response; TAR syndrome; Notch signaling pathway"	"30"	"0"	"2.7"	"0.0"	"4.4"	"3.5"	"3.1"	"4.3"	"8.5"	"0.0"	"98.7"	"105.1"	"251.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62304"	"Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1"	"0.000"	""	"52"	"3"	"7"	"3"	"92"	"10.8"	"9.44"	"1072.64"	"16.80"	"1"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6635"	"ENSG00000182004"	"SNRPE"	"B2R5B9; hsa:6635; P08578; P62304; Q15498; Q5BKT2"	"mRNA Splicing - Major Pathway; snRNP Assembly; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"108.4"	"82.9"	"126.0"	"105.0"	"77.0"	"94.9"	"202.3"	"0.3"	"740.1"	"834.6"	"2394.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00013"	"55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2"	"0.000"	""	"15"	"5"	"9"	"5"	"466"	"52.3"	"7.37"	"1364.96"	"16.77"	"4"	"5"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;kinase activity"	"Pf00018, Pf00595, Pf00625"	"4354"	"ENSG00000130830"	"MPP1"	"B4DZV5; G3XAI1; hsa:4354; Q00013; Q2TSB6; Q5J7V5"	"Sensory processing of sound by outer hair cells of the cochlea"	"MECP2 and associated Rett syndrome"	"2"	"0"	"43.9"	"22.9"	"47.1"	"51.0"	"46.3"	"48.1"	"88.7"	"4.7"	"1003.1"	"945.3"	"1884.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZI7"	"Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1"	"0.000"	""	"13"	"6"	"9"	"6"	"483"	"57.7"	"9.48"	"2405.25"	"16.77"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03467"	"65109"	"ENSG00000125351"	"UPF3B"	"D3DWI3; D3DWI4; hsa:65109; Q0VAK8; Q9BZI7; Q9H1J0"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	""	"6"	"0"	"130.1"	"104.9"	"113.2"	"126.5"	"107.6"	"127.5"	"498.2"	"2.5"	"1889.6"	"1669.5"	"4176.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49458"	"Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2"	"0.000"	""	"40"	"5"	"11"	"5"	"86"	"10.1"	"7.97"	"1487.29"	"16.75"	"3"	"5"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf05486"	"6726"	"ENSG00000143742"	"SRP9"	"A8K0N0; hsa:6726; P49458; Q6NVX0; Q8WTW0"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"80.4"	"65.0"	"73.6"	"74.0"	"70.9"	"76.9"	"200.6"	"6.7"	"5064.1"	"3800.1"	"7711.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C6"	"Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1"	"0.000"	""	"36"	"5"	"10"	"5"	"166"	"18.2"	"7.99"	"1901.89"	"16.72"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"other molecular function"	"Pf00160"	"51645"	"ENSG00000137168"	"PPIL1"	"hsa:51645; O15001; Q5TDC9; Q9Y3C6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"195.9"	"164.2"	"174.3"	"169.2"	"159.5"	"182.3"	"455.0"	"0.0"	"2182.6"	"2270.8"	"4410.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43250"	"G protein-coupled receptor kinase 6 OS=Homo sapiens OX=9606 GN=GRK6 PE=1 SV=2"	"0.000"	""	"10"	"4"	"8"	"4"	"576"	"65.9"	"8.00"	"1530.90"	"16.72"	"4"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00615"	"2870"	"ENSG00000198055"	"GRK6"	"hsa:2870; O60541; P43250; Q13652"	"G alpha (s) signalling events"	"Follicle stimulating hormone (FSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Calcium regulation in cardiac cells; 5q35 copy number variation"	"7"	"0"	"40.6"	"25.3"	"41.2"	"42.7"	"40.8"	"39.4"	"113.1"	"0.4"	"1175.0"	"1183.2"	"2188.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HP4"	"Oxidoreductase NAD-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXNAD1 PE=1 SV=1"	"0.000"	""	"13"	"3"	"7"	"3"	"312"	"34.8"	"8.37"	"1355.69"	"16.66"	"2"	"3"	""	""	"other molecular function"	"Pf00175"	"92106"	"ENSG00000154814"	"OXNAD1"	"hsa:92106; Q2HYC7; Q59FA4; Q96HP4"	""	""	"0"	"0"	"41.7"	"30.5"	"47.6"	"49.6"	"59.0"	"66.4"	"102.2"	"4.9"	"754.5"	"723.0"	"1638.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10606"	"Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2"	"0.000"	""	"35"	"5"	"11"	"5"	"129"	"13.7"	"8.81"	"2150.10"	"16.65"	"5"	"4"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01215"	"1329"	"ENSG00000135940"	"COX5B"	"hsa:1329; P10606; Q53YB7; Q96J18; Q99610"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"7"	"0"	"152.5"	"119.0"	"159.1"	"148.0"	"137.4"	"128.8"	"278.4"	"2.1"	"2282.0"	"2465.6"	"4623.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48059"	"LIM and senescent cell antigen-like-containing domain protein 1 OS=Homo sapiens OX=9606 GN=LIMS1 PE=1 SV=4"	"0.000"	""	"18"	"4"	"5"	"4"	"325"	"37.2"	"8.05"	"404.79"	"16.65"	"1"	"4"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00412"	"3987"	"ENSG00000169756"	"LIMS1"	"B2RAJ4; B7Z483; B7Z7R3; B7Z907; hsa:3987; P48059; Q53TE0; Q9BS44"	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"Primary focal segmental glomerulosclerosis (FSGS)"	"3"	"0"	"73.2"	"63.0"	"86.3"	"75.1"	"88.0"	"42.0"	"116.4"	"0.1"	"1803.0"	"1712.5"	"3209.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T9A4"	"ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1"	"0.000"	""	"8"	"6"	"12"	"1"	"648"	"72.5"	"9.20"	"2488.32"	"16.63"	"6"	"5"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"83858"	"ENSG00000160072"	"ATAD3B"	"A8K3H1; hsa:83858; Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7"	"Neutrophil degranulation"	"1p36 copy number variation syndrome"	"2"	"5"	"294.8"	"260.3"	"281.2"	"268.5"	"204.7"	"258.1"	"863.8"	"6.3"	"2466.2"	"2457.4"	"4243.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWH9"	"SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2"	"0.000"	""	"7"	"5"	"10"	"5"	"1034"	"117.1"	"7.87"	"1794.71"	"16.62"	"5"	"5"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf02037"	"79811"	"ENSG00000137776"	"SLTM"	"A8K5V8; B2RTX3; hsa:79811; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3; Q9H8U9; Q9NWH9"	""	""	"0"	"0"	"217.7"	"218.7"	"264.1"	"220.4"	"185.7"	"252.4"	"717.5"	"1.7"	"1399.7"	"1395.3"	"2461.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43148"	"mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1"	"0.000"	""	"12"	"5"	"9"	"5"	"476"	"54.8"	"6.61"	"1588.47"	"16.56"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03291"	"8731"	"ENSG00000101654"	"RNMT"	"B0YJ90; D3DUJ5; hsa:8731; O43148; O94996; Q9UIJ9"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"mRNA processing; 15q25 copy number variation"	"5"	"0"	"120.6"	"96.9"	"136.0"	"116.7"	"117.0"	"117.6"	"279.4"	"8.1"	"1566.9"	"1499.3"	"3045.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05387"	"60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1"	"0.000"	""	"40"	"4"	"9"	"3"	"115"	"11.7"	"4.54"	"2512.94"	"16.56"	"4"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00428"	"6181"	"ENSG00000177600"	"RPLP2"	"hsa:6181; P05387; Q6FG96"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins; Opioid receptor pathways"	"16"	"1"	"71.1"	"65.6"	"98.0"	"86.4"	"76.5"	"96.9"	"349.1"	"20.5"	"2285.4"	"2348.2"	"3392.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZJ0"	"Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4"	"0.000"	""	"8"	"4"	"7"	"4"	"848"	"100.4"	"8.00"	"1168.31"	"16.55"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf02184"	"51340"	"ENSG00000101343"	"CRNKL1"	"A8K9T4; hsa:51340; Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ0; Q9BZJ1; Q9BZJ2; Q9GZW7; Q9H8F8; Q9NQH5; Q9NYD8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"47.5"	"46.1"	"49.5"	"39.4"	"38.0"	"47.4"	"112.8"	"1.7"	"785.1"	"862.8"	"1563.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14974"	"Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1"	"0.000"	""	"8"	"6"	"10"	"6"	"1030"	"115.2"	"5.40"	"1535.93"	"16.55"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00023, Pf15898"	"4659"	"ENSG00000058272"	"PPP1R12A"	"B4DZ09; F8VWB4; hsa:4659; O14974; Q2NKL4; Q569H0; Q86WU3; Q8NFR6; Q9BYH0"	"Regulation of PLK1 Activity at G2/M Transition; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"Focal adhesion; Hippo-Merlin signaling dysregulation; Regulation of actin cytoskeleton"	"8"	"0"	"122.5"	"99.6"	"109.0"	"123.2"	"101.6"	"132.7"	"259.3"	"4.0"	"1370.8"	"1388.9"	"2570.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NY12"	"H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1"	"0.000"	""	"22"	"5"	"9"	"5"	"217"	"22.3"	"10.92"	"1272.58"	"16.51"	"4"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf04410"	"54433"	"ENSG00000109534"	"GAR1"	"hsa:54433; Q5MJQ2; Q9NY12"	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	""	"2"	"0"	"148.3"	"104.5"	"158.8"	"142.6"	"171.8"	"141.1"	"347.3"	"8.6"	"2274.5"	"2305.1"	"4798.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22570"	"NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=FDXR PE=1 SV=3"	"0.000"	""	"13"	"5"	"8"	"5"	"491"	"53.8"	"8.44"	"944.03"	"16.48"	"3"	"5"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf07992"	"2232"	"ENSG00000161513"	"FDXR"	"B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; hsa:2232; P22570; Q13716; Q4PJI0; Q9BU12"	"Endogenous sterols; Pregnenolone biosynthesis; Defective CYP11A1 causes AICSR; Electron transport from NADPH to Ferredoxin"	"Iron-sulfur cluster biogenesis"	"5"	"0"	"62.5"	"47.9"	"80.6"	"71.4"	"73.3"	"59.7"	"101.1"	"0.0"	"1265.0"	"1304.7"	"2385.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPW8"	"Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1"	"0.000"	""	"19"	"3"	"5"	"3"	"284"	"33.3"	"9.31"	"1088.15"	"16.48"	"2"	"3"	"other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf07978"	"8508"	"ENSG00000184117"	"NIPSNAP1"	"B2RAY3; hsa:8508; O43800; Q9BPW8"	""	""	"0"	"0"	"20.3"	"9.3"	"25.6"	"23.8"	"28.0"	"25.6"	"53.9"	"0.0"	"362.1"	"369.7"	"733.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y520"	"Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4"	"0.000"	""	"2"	"7"	"12"	"5"	"2896"	"316.7"	"9.13"	"1762.26"	"16.44"	"5"	"6"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	""	"Pf07001"	"23215"	"ENSG00000117523"	"PRRC2C"	"hsa:23215; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3; Q9UF29; Q9UPQ6; Q9Y520"	""	"VEGFA-VEGFR2 signaling"	"1"	"1"	"184.8"	"119.7"	"188.5"	"208.0"	"192.9"	"201.3"	"325.0"	"1.1"	"1253.5"	"1438.6"	"2102.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13868"	"Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2"	"0.000"	""	"24"	"5"	"8"	"5"	"293"	"32.8"	"7.50"	"1583.51"	"16.38"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14382, Pf15985"	"23404"	"ENSG00000130713"	"EXOSC2"	"A3KFL3; A3KFL4; B4DKK6; hsa:23404; Q13868; Q9NUY4"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"Ciliary landscape"	"7"	"0"	"59.9"	"35.4"	"72.4"	"64.8"	"65.6"	"54.5"	"153.2"	"1.9"	"1033.6"	"1057.6"	"2537.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVP2"	"Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2"	"0.000"	""	"13"	"5"	"8"	"5"	"549"	"62.0"	"9.16"	"1610.74"	"16.38"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf08701"	"26354"	"ENSG00000163938"	"GNL3"	"B2RDC1; hsa:26354; Q5PU80; Q96SV6; Q96SV7; Q9BVP2; Q9UJY0"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"44.4"	"29.4"	"52.1"	"50.8"	"38.9"	"52.4"	"115.5"	"4.4"	"971.1"	"985.8"	"1938.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWX8"	"Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3"	"0.000"	""	"6"	"5"	"7"	"5"	"916"	"103.6"	"9.04"	"822.33"	"16.36"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01585, Pf01805, Pf04818"	"10523"	"ENSG00000085872"	"CHERP"	"hsa:10523; O00302; Q4G0Y5; Q8IWX8; Q8WU30; Q99492"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"284.8"	"222.2"	"230.2"	"259.3"	"237.8"	"243.8"	"334.5"	"4.6"	"1626.5"	"1691.0"	"3481.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14635"	"G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1"	"0.000"	""	"11"	"4"	"8"	"4"	"433"	"48.3"	"7.47"	"1286.74"	"16.34"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"891"	"ENSG00000134057"	"CCNB1"	"A8K066; hsa:891; P14635; Q5TZP9"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Transcriptional regulation by RUNX2; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; Initiation of Nuclear Envelope (NE) Reformation; Polo-like kinase mediated events; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Phosphorylation of Emi1"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATM signaling pathway; G1 to S cell cycle control; GDNF signaling; DNA damage response"	"31"	"0"	"139.6"	"113.6"	"153.3"	"127.5"	"123.8"	"125.9"	"240.4"	"3.1"	"1232.0"	"1266.4"	"2411.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75052"	"Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Homo sapiens OX=9606 GN=NOS1AP PE=1 SV=3"	"0.000"	""	"14"	"5"	"9"	"5"	"506"	"56.1"	"6.30"	"1268.02"	"16.32"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00640"	"9722"	"ENSG00000198929"	"NOS1AP"	"B7ZLF5; hsa:9722; O43564; O75052; Q3T551; Q5VU95"	""	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"1"	"0"	"59.9"	"40.6"	"49.4"	"67.9"	"64.9"	"53.8"	"108.2"	"3.6"	"935.8"	"973.2"	"2156.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14950"	"Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2"	"0.000"	""	"41"	"4"	"8"	"4"	"172"	"19.8"	"4.84"	"1934.18"	"16.30"	"3"	"3"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08976, Pf13405"	"103910; 10627"	"ENSG00000118680"	"MYL12B"	"D3DUH6; hsa:103910; O14950; Q13182; Q7Z5Z4"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"Thyroid stimulating hormone (TSH) signaling pathway; Focal adhesion"	"9"	"0"	"51.9"	"34.8"	"58.9"	"54.7"	"59.7"	"47.7"	"90.5"	"5.2"	"1329.7"	"1429.5"	"3684.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78344"	"Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1"	"0.000"	""	"8"	"5"	"9"	"5"	"907"	"102.3"	"7.14"	"1603.63"	"16.16"	"4"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"1982"	"ENSG00000110321"	"EIF4G2"	"hsa:1982; O60877; P78344; P78404; Q0VH00; Q0VH01; Q2NKW9; Q49A79; Q53EU1; Q58EZ2; Q8NI71; Q96C16"	"ISG15 antiviral mechanism"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation; Acute viral myocarditis"	"4"	"0"	"130.2"	"98.8"	"143.5"	"131.9"	"137.2"	"136.2"	"197.7"	"0.9"	"1144.7"	"1172.5"	"2395.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99590"	"Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2"	"0.000"	""	"5"	"7"	"11"	"5"	"1463"	"164.6"	"8.41"	"1958.29"	"16.14"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	""	"9169"	"ENSG00000139218"	"SCAF11"	"A6NEU9; A6NLW5; hsa:9169; Q8IW59; Q99590"	""	"Apoptosis"	"1"	"1"	"295.8"	"236.9"	"282.9"	"250.4"	"221.6"	"267.7"	"721.3"	"3.9"	"3064.1"	"3087.7"	"5603.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23258"	"Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2"	"0.000"	""	"17"	"5"	"13"	"5"	"451"	"51.1"	"6.14"	"3058.46"	"16.11"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7283"	"ENSG00000131462"	"TUBG1"	"hsa:7283; P23258; Q53X79; Q9BW59"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"Alstrom syndrome"	"8"	"0"	"72.3"	"64.6"	"96.5"	"59.9"	"68.5"	"98.4"	"139.9"	"9.6"	"2150.0"	"2234.3"	"3739.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13427"	"Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2"	"0.000"	""	"8"	"6"	"12"	"6"	"754"	"88.6"	"10.29"	"2264.99"	"16.07"	"6"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"9360"	"ENSG00000138398"	"PPIG"	"D3DPC5; D3DPC6; hsa:9360; O00706; Q13427; Q53R40; Q53SN4; Q96DG9"	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	""	"2"	"0"	"150.7"	"119.7"	"180.2"	"165.2"	"173.4"	"150.2"	"345.8"	"3.4"	"1429.6"	"1365.4"	"2834.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11177"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3"	"0.000"	""	"12"	"3"	"5"	"3"	"359"	"39.2"	"6.65"	"1079.71"	"16.03"	"2"	"3"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02779, Pf02780"	"5162"	"ENSG00000168291"	"PDHB"	"B2R7L0; B4DDD7; hsa:5162; P11177; Q6FH45; Q9BQ27; Q9UFK3"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"Metabolic reprogramming in colon cancer; Orexin receptor pathway"	"6"	"0"	"56.7"	"38.6"	"69.7"	"57.5"	"57.3"	"62.5"	"145.9"	"0.0"	"773.9"	"721.9"	"1458.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13984"	"General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2"	"0.000"	""	"24"	"5"	"10"	"5"	"249"	"28.4"	"9.23"	"1842.22"	"16.02"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02270, Pf17683"	"2963"	"ENSG00000188342"	"GTF2F2"	"A6NNS5; hsa:2963; P13984; Q5W0H3"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"Eukaryotic transcription initiation"	"33"	"0"	"62.9"	"45.6"	"67.8"	"57.1"	"58.5"	"56.5"	"117.4"	"4.1"	"1117.0"	"1142.0"	"3148.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57076"	"Cilia- and flagella-associated protein 298 OS=Homo sapiens OX=9606 GN=CFAP298 PE=1 SV=1"	"0.000"	""	"17"	"3"	"6"	"3"	"290"	"33.2"	"7.44"	"844.56"	"16.00"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	"Pf11069"	"56683"	"ENSG00000159079"	"CFAP298"	"hsa:56683; P57076; Q53FH0"	""	"Ciliopathies"	"1"	"0"	"96.6"	"80.5"	"81.2"	"91.7"	"105.5"	"115.9"	"159.1"	"2.7"	"878.8"	"870.2"	"1619.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW27"	"Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85 PE=1 SV=1"	"0.000"	""	"7"	"4"	"8"	"4"	"656"	"75.0"	"5.55"	"1697.26"	"15.99"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07575"	"79902"	"ENSG00000125450"	"NUP85"	"B4DMQ3; B4DPW1; hsa:79902; Q8NDI4; Q9BW27; Q9H9U1"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Postmitotic nuclear pore complex (NPC) reformation"	""	"35"	"0"	"146.4"	"135.2"	"192.7"	"163.8"	"158.1"	"116.6"	"220.4"	"4.5"	"1451.9"	"1464.6"	"2870.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08559"	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3"	"0.000"	""	"15"	"5"	"10"	"5"	"390"	"43.3"	"8.06"	"1890.68"	"15.92"	"5"	"5"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676"	"5160"	"ENSG00000131828"	"PDHA1"	"A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; hsa:5160; P08559; Q53H41; Q5JPT8; Q9NP12; Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Lipid metabolism pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Acetylcholine synthesis; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"15"	"0"	"178.1"	"156.8"	"196.6"	"175.2"	"178.0"	"171.1"	"454.2"	"1.1"	"1360.5"	"1421.3"	"2317.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62829"	"60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1"	"0.000"	""	"34"	"4"	"6"	"4"	"140"	"14.9"	"10.51"	"477.18"	"15.91"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00238"	"9349"	"ENSG00000125691"	"RPL23"	"hsa:9349; P23131; P24048; P62829; Q29246; Q3SWV7; Q6P5S1"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins; 17q12 copy number variation syndrome"	"15"	"0"	"212.2"	"182.3"	"209.6"	"200.5"	"172.3"	"183.4"	"504.3"	"0.6"	"2398.5"	"2573.1"	"5281.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GM8"	"Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1"	"0.000"	""	"10"	"4"	"8"	"4"	"510"	"56.5"	"7.18"	"1214.99"	"15.86"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf04857"	"114034"	"ENSG00000132773"	"TOE1"	"B4DEM6; hsa:114034; Q6IA35; Q8IWN5; Q96GM8; Q9H846"	""	""	"0"	"0"	"61.8"	"46.8"	"96.9"	"74.3"	"72.3"	"78.3"	"151.4"	"25.8"	"1079.3"	"1065.8"	"2516.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB3"	"Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3"	"0.000"	""	"5"	"3"	"6"	"2"	"817"	"89.3"	"4.97"	"552.78"	"15.86"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00595, Pf17817"	"84687"	"ENSG00000108819"	"PPP1R9B"	"D3DTX6; hsa:84687; Q8TCR9; Q96SB3"	""	""	"0"	"0"	"18.0"	"12.3"	"13.6"	"15.4"	"20.7"	"18.3"	"29.9"	"0.0"	"146.4"	"154.0"	"290.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16775"	"Hydroxyacylglutathione hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HAGH PE=1 SV=2"	"0.000"	""	"12"	"3"	"10"	"3"	"308"	"33.8"	"8.12"	"2112.76"	"15.84"	"3"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00753, Pf16123"	"3029"	"ENSG00000063854"	"HAGH"	"A8K290; B4DP33; B4DRA7; E7EN93; hsa:3029; Q16775"	""	""	"0"	"0"	"91.7"	"89.3"	"102.0"	"102.8"	"96.9"	"91.8"	"181.2"	"3.4"	"672.8"	"707.3"	"1134.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00629"	"Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1"	"0.000"	""	"11"	"3"	"4"	"2"	"521"	"57.9"	"4.96"	"537.09"	"15.83"	"1"	"3"	"cell-cell signaling;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3840"	"ENSG00000186432"	"KPNA4"	"A8K4S6; D3DNM2; hsa:3840; O00190; O00629"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"Leptin signaling pathway"	"3"	"1"	"44.9"	"36.7"	"67.9"	"52.6"	"49.8"	"41.2"	"103.4"	"1.2"	"641.1"	"699.3"	"1640.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49590"	"Histidine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=HARS2 PE=1 SV=1"	"0.000"	""	"12"	"6"	"11"	"1"	"506"	"56.9"	"8.24"	"1640.18"	"15.83"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03129, Pf13393"	"23438"	"ENSG00000112855"	"HARS2"	"B4DDY8; hsa:23438; P49590"	"Mitochondrial tRNA aminoacylation"	"Primary ovarian insufficiency"	"2"	"0"	"4.8"	"3.4"	"9.9"	"5.5"	"5.1"	"2.4"	"8.4"	"1.2"	"66.9"	"60.7"	"144.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07196"	"Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3"	"0.000"	""	"10"	"4"	"8"	"4"	"543"	"61.5"	"4.65"	"1651.16"	"15.80"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"4747"	"ENSG00000277586"	"NEFL"	"B9ZVN2; hsa:4747; P07196; Q16154; Q8IU72"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; NO/cGMP/PKG mediated neuroprotection; Ciliary landscape; Intracellular trafficking proteins involved in CMT neuropathy; CCL18 signaling pathway"	"12"	"0"	"117.8"	"95.9"	"144.8"	"126.1"	"134.6"	"126.7"	"159.7"	"3.5"	"700.1"	"691.3"	"1292.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0C2"	"182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1 PE=1 SV=4"	"0.000"	""	"4"	"5"	"10"	"5"	"1729"	"181.7"	"4.86"	"1557.14"	"15.69"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15327"	"85456"	"ENSG00000149115"	"TNKS1BP1"	"A7E2F8; hsa:85456; Q6PJ35; Q6ZV74; Q9C0C2"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"Ciliary landscape"	"3"	"0"	"92.5"	"61.1"	"74.7"	"77.5"	"81.8"	"66.2"	"139.7"	"10.0"	"669.2"	"650.2"	"1183.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43897"	"Elongation factor Ts, mitochondrial OS=Homo sapiens OX=9606 GN=TSFM PE=1 SV=2"	"0.000"	""	"14"	"4"	"5"	"4"	"325"	"35.4"	"8.38"	"691.94"	"15.67"	"1"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf00889"	"10102"	"ENSG00000123297"	"TSFM"	"B4E391; F5H2T7; hsa:10102; P43897; Q561V7; Q8TBC2; Q9UQK0"	"Mitochondrial translation elongation"	""	"1"	"0"	"55.4"	"36.5"	"55.3"	"57.0"	"50.7"	"50.1"	"120.0"	"6.5"	"1980.4"	"2072.8"	"4319.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK45"	"U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1"	"0.000"	""	"64"	"4"	"6"	"4"	"103"	"11.6"	"5.27"	"536.94"	"15.63"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51690"	"ENSG00000130332"	"LSM7"	"hsa:51690; Q9UK45"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"mRNA processing"	"3"	"0"	"57.4"	"28.0"	"68.2"	"69.1"	"63.4"	"60.4"	"138.7"	"0.0"	"724.0"	"691.8"	"1833.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15118"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial OS=Homo sapiens OX=9606 GN=PDK1 PE=1 SV=1"	"0.000"	""	"20"	"5"	"8"	"5"	"436"	"49.2"	"8.81"	"1198.17"	"15.61"	"3"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5163"	"ENSG00000152256"	"PDK1"	"B2R6T1; B7Z937; D3DPD8; E9PD65; hsa:5163; Q15118; Q308M4"	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"T cell receptor and co-stimulatory signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Non-small cell lung cancer; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Aspirin and miRNAs; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; TCA cycle in senescence; Pleural mesothelioma; Orexin receptor pathway; Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution; Glucose metabolism in triple-negative breast cancer cells; EPO receptor signaling; DNA damage response (only ATM dependent)"	"19"	"0"	"28.8"	"24.5"	"28.7"	"21.8"	"28.7"	"23.6"	"51.3"	"2.4"	"650.2"	"678.5"	"1343.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94813"	"Slit homolog 2 protein OS=Homo sapiens OX=9606 GN=SLIT2 PE=1 SV=1"	"0.000"	""	"5"	"6"	"9"	"6"	"1529"	"169.8"	"7.06"	"1790.44"	"15.61"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00008, Pf01462, Pf01463, Pf02210, Pf12661, Pf13855"	"9353"	"ENSG00000145147"	"SLIT2"	"A0A0A6YYB8; B7ZLR5; hsa:9353; O94813; O95710; Q17RU3; Q9Y5Q7"	"Regulation of expression of SLITs and ROBOs; Netrin-1 signaling; Inactivation of CDC42 and RAC1; Activation of RAC1; Regulation of commissural axon pathfinding by SLIT and ROBO; Role of ABL in ROBO-SLIT signaling; SLIT2:ROBO1 increases RHOA activity"	"Spinal cord injury; Robo4 and VEGF signaling pathways crosstalk; Genes controlling nephrogenesis; GDNF/RET signaling axis; Development of ureteric collection system"	"13"	"0"	"39.3"	"22.9"	"38.0"	"29.4"	"36.5"	"27.7"	"157.3"	"0.0"	"1219.9"	"1530.9"	"2472.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTV0"	"PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1"	"0.000"	""	"45"	"5"	"8"	"5"	"110"	"12.4"	"8.41"	"897.21"	"15.57"	"3"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03660"	"84844"	"ENSG00000100410"	"PHF5A"	"hsa:84844; Q7RTV0; Q9UH06"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"511.7"	"400.8"	"456.3"	"429.5"	"363.2"	"326.8"	"1135.5"	"0.0"	"2718.4"	"2767.0"	"5307.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15007"	"Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2"	"0.000"	""	"15"	"4"	"8"	"4"	"396"	"44.2"	"5.19"	"1660.30"	"15.51"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf17098"	"9589"	"ENSG00000146457"	"WTAP"	"hsa:9589; Q15007; Q5TCL8; Q5TCL9; Q96T28; Q9BYJ7; Q9H4E2"	"Processing of Capped Intron-Containing Pre-mRNA"	""	"1"	"0"	"47.7"	"33.7"	"44.4"	"32.3"	"40.0"	"46.1"	"73.6"	"4.5"	"561.1"	"534.1"	"1553.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50454"	"Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2"	"0.000"	""	"14"	"3"	"4"	"3"	"418"	"46.4"	"8.69"	"432.96"	"15.49"	"1"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00079"	"871"	"ENSG00000149257"	"SERPINH1"	"B3KVJ3; hsa:871; P29043; P50454; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88"	"Collagen biosynthesis and modifying enzymes"	"Endochondral ossification; Type I collagen synthesis in the context of osteogenesis imperfecta; Endochondral ossification with skeletal dysplasias; 15q13.3 copy number variation syndrome; 15q11q13 copy number variation"	"6"	"0"	"16.8"	"14.7"	"28.4"	"23.2"	"27.3"	"22.3"	"48.0"	"1.8"	"384.9"	"404.7"	"793.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53EL6"	"Programmed cell death protein 4 OS=Homo sapiens OX=9606 GN=PDCD4 PE=1 SV=2"	"0.000"	""	"9"	"3"	"7"	"3"	"469"	"51.7"	"5.21"	"1581.19"	"15.49"	"2"	"3"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02847"	"27250"	"ENSG00000150593"	"PDCD4"	"B2RCV4; B5ME91; hsa:27250; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"Translation inhibitors in chronically activated PDGFRA cells; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"4"	"0"	"40.1"	"40.2"	"47.6"	"44.4"	"49.2"	"50.4"	"64.9"	"3.4"	"956.6"	"1064.3"	"2913.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14151"	"Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1"	"0.000"	""	"4"	"4"	"10"	"1"	"953"	"107.4"	"6.16"	"1780.73"	"15.37"	"4"	"4"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"9667"	"ENSG00000130254"	"SAFB2"	"B4DKG3; hsa:9667; Q14151; Q8TB13"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62314"	"Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1"	"0.000"	""	"28"	"2"	"8"	"2"	"119"	"13.3"	"11.56"	"1470.45"	"15.37"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"6632"	"ENSG00000167088"	"SNRPD1"	"B5BTZ1; hsa:6632; P13641; P62314"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"mRNA processing"	"5"	"0"	"37.9"	"24.2"	"29.5"	"25.9"	"38.2"	"27.2"	"36.1"	"3.2"	"138.7"	"151.2"	"239.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P6C2"	"RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2"	"0.000"	""	"7"	"2"	"5"	"2"	"394"	"44.2"	"9.09"	"1249.01"	"15.36"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf13532"	"54890"	"ENSG00000091542"	"ALKBH5"	"B4DVJ4; D3DXC6; hsa:54890; Q6P6C2; Q9NXD6"	"Reversal of alkylation damage by DNA dioxygenases"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"2"	"0"	"78.3"	"77.8"	"71.4"	"70.0"	"65.2"	"65.2"	"220.4"	"0.3"	"815.9"	"793.5"	"1861.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RL1"	"BRCA1-A complex subunit RAP80 OS=Homo sapiens OX=9606 GN=UIMC1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"6"	"2"	"719"	"79.7"	"5.45"	"1333.09"	"15.36"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf18282"	"51720"	"ENSG00000087206"	"UIMC1"	"A8MSA1; B3KMZ1; B4E3N2; hsa:51720; Q5XKQ1; Q7Z3W7; Q8N5B9; Q96RL1; Q9BZR1; Q9BZR5; Q9UHX7"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ); Metalloprotease DUBs"	"5q35 copy number variation"	"6"	"0"	"37.1"	"30.5"	"39.9"	"37.0"	"42.0"	"49.4"	"85.7"	"3.2"	"515.4"	"567.0"	"1028.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20962"	"Parathymosin OS=Homo sapiens OX=9606 GN=PTMS PE=1 SV=2"	"0.000"	""	"23"	"2"	"8"	"2"	"102"	"11.5"	"4.16"	"1668.61"	"15.34"	"2"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03247"	"5763"	"ENSG00000159335"	"PTMS"	"hsa:5763; P20962"	""	"IL-18 signaling pathway"	"1"	"0"	"655.7"	"402.8"	"515.9"	"521.9"	"486.1"	"555.0"	"617.4"	"0.0"	"784.3"	"721.7"	"994.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63208"	"S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2"	"0.000"	""	"29"	"3"	"5"	"3"	"163"	"18.6"	"4.54"	"905.50"	"15.31"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01466, Pf03931"	"6500"	"ENSG00000113558"	"SKP1"	"D3DQ97; D3DQ98; hsa:6500; P34991; P63208; Q8TAY2"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Circadian Clock; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; TNF-alpha signaling pathway; Breast cancer pathway; Small cell lung cancer; Notch signaling pathway"	"38"	"0"	"107.6"	"68.4"	"110.0"	"103.6"	"98.6"	"81.3"	"172.8"	"1.4"	"1098.0"	"996.5"	"2209.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6E2"	"Basic leucine zipper and W2 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=BZW2 PE=1 SV=1"	"0.000"	""	"11"	"3"	"4"	"3"	"419"	"48.1"	"6.68"	"258.21"	"15.31"	"1"	"2"	"other biological processes"	"other cell component"	""	"Pf02020"	"28969"	"ENSG00000136261"	"BZW2"	"A4D123; hsa:28969; Q3B779; Q96JW5; Q9H3F7; Q9Y6E2"	""	""	"0"	"0"	"35.4"	"19.2"	"52.3"	"48.0"	"48.7"	"38.8"	"61.9"	"1.6"	"937.1"	"1046.5"	"2572.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L0Y3"	"tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2"	"0.000"	""	"14"	"5"	"7"	"5"	"403"	"47.3"	"9.36"	"885.94"	"15.30"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"54931"	"ENSG00000174173"	"TRMT10C"	"hsa:54931; Q7L0Y3; Q9NRG5; Q9NX54; Q9Y596"	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	""	"3"	"0"	"44.7"	"41.2"	"49.6"	"51.9"	"53.6"	"57.7"	"113.1"	"6.3"	"1007.9"	"954.8"	"2523.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55884"	"Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3"	"0.000"	""	"8"	"5"	"8"	"5"	"814"	"92.4"	"5.00"	"1421.54"	"15.29"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08662"	"8662"	"ENSG00000106263"	"EIF3B"	"A4D208; hsa:8662; P55884; Q2NL77; Q9UMF9"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"116.8"	"74.5"	"139.2"	"120.7"	"135.0"	"119.8"	"205.8"	"2.6"	"1401.7"	"1379.8"	"3534.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1N9"	"Putative deoxyribonuclease TATDN1 OS=Homo sapiens OX=9606 GN=TATDN1 PE=1 SV=2"	"0.000"	""	"19"	"5"	"8"	"5"	"297"	"33.6"	"6.96"	"1034.85"	"15.27"	"3"	"5"	"DNA metabolism"	"nucleus"	"other molecular function"	"Pf01026"	"83940"	"ENSG00000147687"	"TATDN1"	"B2R5J0; hsa:83940; Q6P1N9; Q8TD02; Q9BY40"	""	""	"0"	"0"	"126.2"	"65.1"	"136.9"	"116.1"	"121.5"	"205.3"	"191.2"	"7.4"	"1490.5"	"1531.0"	"3229.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C005"	"Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=DPY30 PE=1 SV=1"	"0.000"	""	"27"	"3"	"6"	"3"	"99"	"11.2"	"4.88"	"931.11"	"15.24"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"ER/Golgi;nucleus"	"other molecular function"	"Pf05186"	"84661"	"ENSG00000162961"	"DPY30"	"D6W578; hsa:84661; Q9C005"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"Kleefstra syndrome"	"5"	"0"	"26.2"	"22.0"	"30.5"	"22.9"	"31.4"	"28.5"	"74.7"	"3.6"	"1135.6"	"1170.9"	"2918.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75822"	"Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2"	"0.000"	""	"20"	"3"	"4"	"3"	"258"	"29.0"	"4.83"	"232.87"	"15.19"	"1"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08597"	"8669"	"ENSG00000104131"	"EIF3J"	"B4DUI3; F5H425; hsa:8669; O75822; Q9BUD2; Q9H8Q2; Q9UI65"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"20.3"	"12.7"	"24.5"	"13.7"	"18.5"	"27.5"	"46.2"	"1.9"	"1031.0"	"1045.4"	"2597.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULP9"	"TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24 PE=1 SV=2"	"0.000"	""	"6"	"3"	"8"	"3"	"559"	"62.9"	"7.36"	"1536.51"	"15.13"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf00566, Pf07534"	"57465"	"ENSG00000162065"	"TBC1D24"	"A0JNW3; B9A6M6; hsa:57465; Q2KJ08; Q9ULP9"	"TBC/RABGAPs"	""	"1"	"0"	"33.7"	"34.3"	"51.4"	"45.0"	"44.5"	"49.5"	"161.5"	"2.7"	"2307.5"	"2127.3"	"3282.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15530"	"3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"6"	"2"	"556"	"63.1"	"7.36"	"1554.64"	"15.10"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf14593"	"5170"	"ENSG00000140992"	"PDPK1"	"H0Y4Z0; hsa:5170; O15530; Q59EH6; Q6FI20; Q8IV52; Q9BRD5"	"Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; G beta:gamma signalling through PI3Kgamma; RHO GTPases activate PKNs; Activation of AKT2; Integrin signaling; RSK activation; VEGFR2 mediated vascular permeability; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways"	"MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac hypertrophic response; Focal adhesion; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; PPAR signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Modulators of TCR signaling and T cell activation; GDNF signaling; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway"	"46"	"0"	"12.5"	"5.1"	"7.4"	"8.8"	"11.1"	"18.0"	"47.0"	"0.0"	"337.0"	"364.6"	"638.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TBB1"	"Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1"	"0.000"	""	"17"	"3"	"4"	"3"	"312"	"35.1"	"9.13"	"390.73"	"15.07"	"1"	"3"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf09468, Pf17745"	"79621"	"ENSG00000136104"	"RNASEH2B"	"G3XAJ1; hsa:79621; Q05DR2; Q5TBB1; Q6PK48; Q9HAF7"	""	""	"0"	"0"	"48.6"	"47.6"	"48.1"	"44.7"	"42.4"	"56.5"	"81.0"	"0.0"	"821.3"	"788.3"	"1587.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00401"	"Neural Wiskott-Aldrich syndrome protein OS=Homo sapiens OX=9606 GN=WASL PE=1 SV=2"	"0.000"	""	"6"	"3"	"4"	"3"	"505"	"54.8"	"7.93"	"363.62"	"15.03"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00568, Pf00786, Pf02205"	"8976"	"ENSG00000106299"	"WASL"	"A1JUI9; hsa:8976; O00401; Q7Z746"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RHOJ GTPase cycle; RHOV GTPase cycle; NOSTRIN mediated eNOS trafficking; Nephrin family interactions; EPHB-mediated forward signaling; DCC mediated attractive signaling"	"Pathogenic Escherichia coli infection; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Chemokine signaling pathway; G13 signaling pathway"	"17"	"0"	"9.1"	"10.5"	"25.2"	"19.2"	"18.0"	"24.5"	"48.1"	"1.3"	"478.5"	"491.9"	"961.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W42"	"THO complex subunit 6 homolog OS=Homo sapiens OX=9606 GN=THOC6 PE=1 SV=1"	"0.000"	""	"12"	"4"	"8"	"4"	"341"	"37.5"	"7.43"	"1876.35"	"15.03"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"79228"	"ENSG00000131652"	"THOC6"	"B2RA85; hsa:79228; Q86W42; Q8NBR1; Q9BTV9"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"109.8"	"88.1"	"100.8"	"84.8"	"90.2"	"80.2"	"251.0"	"0.0"	"921.6"	"915.6"	"1662.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13613"	"Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4"	"0.000"	""	"10"	"5"	"8"	"5"	"665"	"74.6"	"7.14"	"1074.83"	"15.01"	"3"	"5"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"8776"	"ENSG00000063601"	"MTMR1"	"A0A024RC07; hsa:8776; Q13613; Q9UBX6; Q9UEM0; Q9UQD5"	"RHOF GTPase cycle; Synthesis of PIPs at the plasma membrane"	""	"2"	"0"	"58.8"	"44.1"	"62.7"	"57.8"	"57.3"	"54.2"	"125.2"	"1.9"	"1258.1"	"1225.8"	"2091.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16891"	"MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1"	"0.000"	""	"6"	"5"	"9"	"5"	"758"	"83.6"	"6.48"	"1249.59"	"15.01"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf09731"	"10989"	"ENSG00000132305"	"IMMT"	"B1H0U5; B2R5N6; hsa:10989; Q14539; Q15092; Q16891; Q68D41; Q69HW5; Q6IBL0; Q7Z3X1; Q8TAJ5; Q9P0V2"	"Cristae formation"	""	"1"	"0"	"61.1"	"45.1"	"74.9"	"66.8"	"66.9"	"68.6"	"119.7"	"0.8"	"867.9"	"883.7"	"1802.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09012"	"U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3"	"0.000"	""	"15"	"5"	"11"	"3"	"282"	"31.3"	"9.83"	"1510.89"	"14.99"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6626"	"ENSG00000077312"	"SNRPA"	"hsa:6626; P09012"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"2"	"1072.7"	"692.8"	"1085.2"	"974.7"	"855.6"	"849.1"	"1142.4"	"0.0"	"2647.6"	"2680.9"	"4160.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76094"	"Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3"	"0.000"	""	"9"	"4"	"6"	"4"	"671"	"74.6"	"9.26"	"719.90"	"14.99"	"2"	"4"	"transport"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08492, Pf13181, Pf17004"	"6731"	"ENSG00000174780"	"SRP72"	"G5E9Z8; hsa:6731; O76094; Q7Z3C0"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"2.8"	"2.8"	"3.2"	"7.9"	"5.7"	"7.4"	"21.0"	"4.0"	"177.8"	"176.9"	"409.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60645"	"Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3"	"0.000"	""	"10"	"5"	"8"	"5"	"745"	"85.5"	"6.29"	"1696.22"	"14.98"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06046"	"11336"	"ENSG00000180104"	"EXOC3"	"hsa:11336; O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"27.1"	"16.0"	"27.5"	"25.4"	"17.9"	"15.7"	"67.8"	"6.4"	"539.7"	"499.3"	"898.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14573"	"Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens OX=9606 GN=ITPR3 PE=1 SV=2"	"0.000"	""	"2"	"5"	"8"	"3"	"2671"	"303.9"	"6.48"	"1441.46"	"14.96"	"4"	"4"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3710"	"ENSG00000096433"	"ITPR3"	"hsa:3710; Q14573; Q14649; Q5TAQ2"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Sensory perception of sweet, bitter, and umami (glutamate) taste; Ion homeostasis; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; MFAP5-mediated ovarian cancer cell motility and invasiveness; GPR40 pathway; Vitamin D-sensitive calcium signaling in depression; Airway smooth muscle cell contraction; Pleural mesothelioma; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"25"	"0"	"53.6"	"41.3"	"48.5"	"47.6"	"48.1"	"48.1"	"78.9"	"5.0"	"567.2"	"577.7"	"1190.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2W4"	"Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3"	"0.000"	""	"6"	"4"	"8"	"4"	"902"	"101.4"	"8.40"	"1575.00"	"14.95"	"4"	"4"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00644, Pf02825, Pf18606, Pf18633"	"56829"	"ENSG00000105939"	"ZC3HAV1"	"A4D1R2; A4D1S4; hsa:56829; Q7Z2W4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7"	"Signaling by BRAF and RAF1 fusions"	""	"1"	"0"	"101.6"	"92.1"	"109.7"	"91.6"	"103.6"	"125.4"	"243.4"	"0.0"	"740.9"	"710.4"	"1407.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969G3"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2"	"0.000"	""	"12"	"3"	"5"	"3"	"411"	"46.6"	"4.88"	"767.29"	"14.93"	"2"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505"	"6605"	"ENSG00000073584"	"SMARCE1"	"B3KMC1; B4DFR4; C0IMW4; C0IMW5; C0IMW7; H7C3F6; hsa:6605; O43539; Q969G3"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"Androgen receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis"	"6"	"0"	"54.6"	"45.6"	"48.2"	"47.8"	"42.3"	"48.3"	"98.3"	"8.6"	"669.2"	"622.8"	"1406.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H1E3"	"Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1"	"0.000"	""	"21"	"3"	"4"	"3"	"243"	"27.3"	"5.08"	"331.83"	"14.88"	"1"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"64710"	"ENSG00000069275"	"NUCKS1"	"hsa:64710; Q54AC0; Q5PXE7; Q9H1D6; Q9H1E3; Q9H723"	""	""	"0"	"0"	"54.3"	"48.1"	"45.5"	"48.3"	"46.9"	"50.7"	"83.3"	"0.0"	"570.7"	"615.0"	"1261.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75909"	"Cyclin-K OS=Homo sapiens OX=9606 GN=CCNK PE=1 SV=2"	"0.000"	""	"6"	"2"	"8"	"2"	"580"	"64.2"	"8.41"	"1664.46"	"14.87"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00134"	"8812"	"ENSG00000090061"	"CCNK"	"hsa:8812; O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"Male infertility"	"10"	"0"	"21.7"	"12.6"	"20.2"	"24.1"	"20.2"	"21.9"	"48.4"	"3.2"	"280.4"	"297.0"	"474.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13647"	"Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3"	"0.000"	""	"8"	"5"	"9"	"2"	"590"	"62.3"	"7.74"	"1257.67"	"14.84"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity;other molecular function"	"Pf00038, Pf16208"	"3852"	"ENSG00000186081"	"KRT5"	"hsa:3852; P13647; Q6PI71; Q6UBJ0; Q8TA91"	"Formation of the cornified envelope; Type I hemidesmosome assembly"	""	"3"	"0"	"31.0"	"91.2"	"23.3"	"75.6"	"25.9"	"403.4"	"97.8"	"4.2"	"420.3"	"427.3"	"802.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJV9"	"Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2"	"0.000"	""	"11"	"6"	"10"	"6"	"622"	"69.8"	"6.84"	"1497.80"	"14.77"	"4"	"5"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51428"	"ENSG00000183258"	"DDX41"	"B2RDC8; hsa:51428; Q96BK6; Q96K05; Q9NT96; Q9NW04; Q9UJV9"	"mRNA Splicing - Major Pathway; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN"	"5q35 copy number variation"	"5"	"0"	"42.3"	"25.0"	"52.9"	"42.3"	"54.4"	"41.0"	"97.2"	"8.3"	"768.2"	"776.5"	"1843.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15785"	"Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2"	"0.000"	""	"17"	"4"	"7"	"4"	"309"	"34.5"	"8.98"	"1326.01"	"14.76"	"3"	"4"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00515"	"10953"	"ENSG00000025772"	"TOMM34"	"hsa:10953; Q15785; Q53GH9; Q6IBN7; Q9NTZ3"	""	""	"0"	"0"	"49.0"	"36.4"	"73.4"	"59.6"	"63.4"	"44.0"	"142.0"	"2.8"	"1245.5"	"1375.4"	"2707.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14923"	"Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3"	"0.000"	""	"5"	"4"	"8"	"3"	"745"	"81.7"	"6.14"	"1559.08"	"14.75"	"4"	"4"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"3728"	"ENSG00000173801"	"JUP"	"hsa:3728; P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle; Neutrophil degranulation; Formation of the cornified envelope; RHOQ GTPase cycle; RHOJ GTPase cycle; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; RHOH GTPase cycle"	"Arrhythmogenic right ventricular cardiomyopathy; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Ectoderm differentiation; Epithelial to mesenchymal transition in colorectal cancer; Opioid receptor pathways"	"21"	"0"	"70.6"	"58.3"	"82.9"	"81.5"	"61.7"	"124.5"	"121.7"	"0.0"	"697.4"	"671.6"	"1470.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHD8"	"Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2"	"0.000"	""	"8"	"4"	"8"	"4"	"586"	"65.4"	"8.97"	"1757.82"	"14.74"	"4"	"4"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"10801"	"ENSG00000184640"	"SEPTIN9"	"A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654; hsa:10801; Q96QF3; Q96QF4; Q96QF5; Q9HA04; Q9UG40; Q9UHD8; Q9Y5W4"	""	""	"0"	"0"	"308.9"	"234.6"	"256.3"	"272.9"	"240.5"	"321.6"	"461.7"	"0.0"	"1837.7"	"1761.5"	"3011.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12931"	"Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3"	"0.000"	""	"7"	"4"	"8"	"3"	"704"	"80.1"	"8.21"	"1483.01"	"14.72"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00183, Pf02518"	"10131"	"ENSG00000126602"	"TRAP1"	"B4DR68; D3DUC8; F5H897; hsa:10131; O43642; O75235; Q12931; Q9UHL5"	"Respiratory electron transport"	"TNF-alpha signaling pathway; Clock-controlled autophagy in bone metabolism"	"3"	"0"	"67.2"	"39.7"	"80.4"	"69.6"	"64.4"	"68.9"	"93.1"	"0.4"	"1014.6"	"1050.9"	"1954.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06210"	"Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3"	"0.000"	""	"7"	"4"	"8"	"4"	"699"	"78.8"	"7.11"	"1633.45"	"14.67"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01380, Pf13522"	"2673"	"ENSG00000198380"	"GFPT1"	"hsa:2673; Q06210; Q53QE6; Q9BXF8"	"XBP1(S) activates chaperone genes; Synthesis of UDP-N-acetyl-glucosamine; Defective GFPT1 causes CMSTA1"	"UDP-derived sugars synthesis in fibroblasts"	"4"	"0"	"34.3"	"19.7"	"35.0"	"29.6"	"31.2"	"24.3"	"57.7"	"2.3"	"547.0"	"511.9"	"1038.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16513"	"Serine/threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1"	"0.000"	""	"7"	"5"	"7"	"5"	"984"	"112.0"	"6.30"	"683.77"	"14.65"	"2"	"5"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433, Pf02185"	"5586"	"ENSG00000065243"	"PKN2"	"B4DQ21; B4DTP5; B4DVG1; D3DT24; hsa:5586; Q08AF4; Q16513; Q9H1W4"	"RAC1 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; RHO GTPases activate PKNs"	"PI3K-Akt signaling pathway"	"6"	"0"	"60.1"	"51.9"	"56.5"	"66.2"	"59.3"	"68.4"	"85.5"	"5.4"	"709.7"	"705.1"	"1323.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHR5"	"SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1"	"0.000"	""	"14"	"4"	"7"	"4"	"308"	"33.9"	"4.84"	"1281.25"	"14.65"	"3"	"4"	"other biological processes"	"cytoskeleton;nucleus"	""	"Pf07818"	"29115"	"ENSG00000161526"	"SAP30BP"	"B3KML7; hsa:29115; Q8N1R5; Q8TDR8; Q96D27; Q9UHR5"	"NoRC negatively regulates rRNA expression"	""	"1"	"0"	"75.0"	"48.7"	"71.9"	"67.5"	"69.7"	"82.8"	"130.2"	"4.3"	"567.5"	"522.8"	"1228.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2NKX8"	"DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1"	"0.000"	""	"4"	"4"	"7"	"4"	"1250"	"141.0"	"5.31"	"1451.81"	"14.64"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"54821"	"ENSG00000186871"	"ERCC6L"	"hsa:54821; Q2NKX8; Q8NCI1; Q96H93; Q9NXQ8"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"58.5"	"47.0"	"56.4"	"59.5"	"66.0"	"49.4"	"92.5"	"0.0"	"546.8"	"542.0"	"1214.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U42"	"Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3"	"0.000"	""	"14"	"5"	"10"	"5"	"306"	"32.7"	"5.06"	"1727.81"	"14.63"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"8106"	"ENSG00000100836"	"PABPN1"	"D3DS49; hsa:8106; O43484; Q86U42"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"mRNA processing"	"6"	"0"	"465.9"	"340.3"	"526.0"	"451.3"	"419.4"	"446.5"	"1230.5"	"0.2"	"2786.1"	"2772.2"	"4815.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10412"	"Histone H1.4 OS=Homo sapiens OX=9606 GN=H1-4 PE=1 SV=2"	"0.000"	""	"33"	"9"	"15"	"2"	"219"	"21.9"	"11.03"	"3512.60"	"14.63"	"9"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3008"	"ENSG00000168298"	"H1-4"	"hsa:3008; P10412; Q4VB25"	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"Pathways affected in adenoid cystic carcinoma"	"3"	"6"	"737.6"	"566.2"	"567.5"	"553.9"	"532.2"	"577.9"	"2351.9"	"0.4"	"7073.7"	"7522.2"	"10919.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16403"	"Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2"	"0.000"	""	"30"	"8"	"14"	"2"	"213"	"21.4"	"10.93"	"3102.03"	"14.63"	"8"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3006"	"ENSG00000187837"	"H1-2"	"A8K4I2; hsa:3006; P16403"	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	""	"2"	"0"	"139.2"	"89.4"	"106.0"	"113.7"	"100.0"	"116.5"	"337.0"	"0.7"	"530.1"	"504.2"	"757.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16402"	"Histone H1.3 OS=Homo sapiens OX=9606 GN=H1-3 PE=1 SV=2"	"0.000"	""	"24"	"7"	"13"	"1"	"221"	"22.3"	"11.02"	"2714.89"	"14.63"	"7"	"4"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3007"	"ENSG00000124575"	"H1-3"	"B2R751; hsa:3007; P16402; Q2M2I2"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF); Apoptosis induced DNA fragmentation"	""	"2"	"0"	"60.7"	"44.4"	"59.0"	"53.3"	"44.9"	"49.9"	"158.8"	"0.0"	"247.1"	"256.1"	"343.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JJ3"	"Engulfment and cell motility protein 2 OS=Homo sapiens OX=9606 GN=ELMO2 PE=1 SV=2"	"0.000"	""	"8"	"6"	"9"	"6"	"720"	"82.6"	"5.90"	"1642.55"	"14.63"	"5"	"4"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf04727, Pf11841, Pf16457"	"63916"	"ENSG00000062598"	"ELMO2"	"E1P5T3; hsa:63916; Q5JVZ6; Q7Z5G9; Q96CJ2; Q96JJ3; Q96ME5; Q96PA9; Q9H938; Q9H9L5; Q9HAH0; Q9NQQ6"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHOG GTPase cycle; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	""	"5"	"0"	"92.6"	"73.5"	"102.5"	"91.6"	"96.6"	"96.9"	"175.3"	"3.1"	"2907.4"	"3070.7"	"6084.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22033"	"Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4"	"0.000"	""	"7"	"4"	"8"	"4"	"750"	"83.1"	"6.93"	"1663.53"	"14.56"	"4"	"4"	"other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01642, Pf02310"	"4594"	"ENSG00000146085"	"MMUT"	"A8K953; hsa:4594; P22033; Q5SYZ3; Q96B11; Q9UD64"	"Propionyl-CoA catabolism; Defective MMAA causes MMA, cblA type; Defective MUT causes MMAM; Cobalamin (Cbl) metabolism"	"Vitamin B12 metabolism; Amino acid metabolism"	"6"	"0"	"39.2"	"26.4"	"34.9"	"36.6"	"41.4"	"42.2"	"89.6"	"1.4"	"766.2"	"709.7"	"1343.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00541"	"Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1"	"0.000"	""	"8"	"5"	"10"	"5"	"588"	"68.0"	"7.33"	"1653.45"	"14.55"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06732, Pf16589"	"23481"	"ENSG00000100029"	"PES1"	"hsa:23481; O00541; Q6IC29"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"165.3"	"146.5"	"152.8"	"142.8"	"134.5"	"145.1"	"477.5"	"8.8"	"2693.1"	"2655.9"	"3563.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15084"	"Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1"	"0.000"	""	"10"	"4"	"7"	"4"	"440"	"48.1"	"5.08"	"1083.77"	"14.52"	"3"	"4"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"10130"	"ENSG00000143870"	"PDIA6"	"B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83; hsa:10130; Q15084; Q53RC7; Q6ZSH5; Q99778"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling"	"5"	"0"	"470.7"	"338.3"	"557.9"	"507.5"	"425.5"	"462.9"	"603.4"	"0.0"	"1464.3"	"1498.4"	"2617.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y265"	"RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"456"	"50.2"	"6.42"	"670.23"	"14.51"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06068, Pf17856"	"8607"	"ENSG00000175792; ENSG00000284901"	"RUVBL1"	"B2R5S0; hsa:8607; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9; Q9Y265"	"DNA Damage Recognition in GG-NER; UCH proteinases; Ub-specific processing proteases; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; Telomere Extension By Telomerase; HATs acetylate histones"	"Gastric cancer network 1; lncRNA in canonical Wnt signaling and colorectal cancer"	"9"	"0"	"94.7"	"71.2"	"99.6"	"89.8"	"101.5"	"91.9"	"138.6"	"19.1"	"1104.5"	"1021.1"	"2283.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9A5"	"CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1"	"0.000"	""	"6"	"3"	"7"	"3"	"744"	"82.3"	"7.78"	"1026.72"	"14.50"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	""	"25904"	"ENSG00000182973"	"CNOT10"	"B7Z7L1; F8WAF2; hsa:25904; Q9BU30; Q9H5J7; Q9H8X1; Q9H9A5; Q9H9W0; Q9HAH3; Q9UFJ2"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"Ciliary landscape"	"3"	"0"	"15.9"	"10.6"	"29.4"	"16.0"	"23.4"	"21.6"	"40.1"	"5.6"	"647.8"	"710.4"	"1266.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13557"	"Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens OX=9606 GN=CAMK2D PE=1 SV=3"	"0.000"	""	"9"	"4"	"9"	"3"	"499"	"56.3"	"7.25"	"1852.46"	"14.48"	"4"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08332"	"817"	"ENSG00000145349"	"CAMK2D"	"A8MVS8; hsa:817; Q13557; Q52PK4; Q59G21; Q8N553; Q9UGH6; Q9UQE9"	"Signaling by BRAF and RAF1 fusions; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Ion transport by P-type ATPases; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; SRF and miRs in smooth muscle differentiation and proliferation; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Disturbed pathways in Duchenne Muscular Dystrophy; Calcium regulation in cardiac cells; ErbB signaling pathway"	"33"	"1"	"89.8"	"70.8"	"106.1"	"91.9"	"96.7"	"83.0"	"165.2"	"1.6"	"1545.1"	"1602.2"	"2932.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21912"	"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3"	"0.000"	""	"14"	"5"	"10"	"5"	"280"	"31.6"	"8.76"	"1625.79"	"14.47"	"5"	"5"	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf13085, Pf13534"	"6390"	"ENSG00000117118"	"SDHB"	"B2R545; hsa:6390; P21912; Q0QEY7; Q9NQ12"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"Electron transport chain: OXPHOS system in mitochondria; Metabolic reprogramming in colon cancer; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; TCA cycle (aka Krebs or citric acid cycle)"	"7"	"0"	"274.5"	"230.3"	"248.6"	"223.7"	"219.2"	"160.5"	"429.8"	"5.9"	"2121.4"	"2303.5"	"3750.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14696"	"LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2"	"0.000"	""	"24"	"5"	"10"	"5"	"234"	"26.1"	"7.78"	"1582.87"	"14.41"	"3"	"5"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf10185"	"23184"	"ENSG00000117899"	"MESD"	"B4DW84; D3DW96; hsa:23184; Q14696; Q969U1"	""	""	"0"	"0"	"70.2"	"52.0"	"88.2"	"79.3"	"82.5"	"80.0"	"208.6"	"0.8"	"2639.8"	"2625.7"	"4930.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T8P6"	"RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3"	"0.000"	""	"6"	"5"	"8"	"5"	"1007"	"113.5"	"9.16"	"1814.61"	"14.39"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01480"	"64062"	"ENSG00000139746"	"RBM26"	"B4DZE0; hsa:64062; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P6; Q5T8P8; Q5U5P5; Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7"	""	""	"0"	"0"	"56.9"	"37.6"	"68.9"	"60.6"	"54.3"	"44.8"	"162.8"	"6.0"	"886.9"	"878.7"	"1895.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46778"	"60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2"	"0.000"	""	"30"	"5"	"9"	"5"	"160"	"18.6"	"10.49"	"1726.85"	"14.38"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf01157"	"6144"	"ENSG00000122026"	"RPL21"	"hsa:6144; P46778; Q16699"	"SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"233.3"	"197.4"	"236.2"	"216.5"	"192.3"	"194.4"	"1021.0"	"4.9"	"2808.4"	"2897.9"	"4795.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1G2"	"Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=CMTR1 PE=1 SV=1"	"0.000"	""	"6"	"5"	"7"	"5"	"835"	"95.3"	"7.05"	"772.19"	"14.38"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf01728"	"23070"	"ENSG00000137200"	"CMTR1"	"A8K949; hsa:23070; Q14670; Q8N1G2; Q96FJ9"	""	""	"0"	"0"	"64.5"	"48.9"	"71.0"	"64.6"	"71.9"	"68.9"	"94.4"	"0.7"	"1695.5"	"1793.4"	"3394.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MU7"	"YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"5"	"3"	"727"	"84.6"	"6.23"	"641.07"	"14.35"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity"	"Pf04146"	"91746"	"ENSG00000083896; ENSG00000275272"	"YTHDC1"	"hsa:91746; Q4W5Q3; Q7Z622; Q8TF35; Q96MU7"	""	""	"0"	"0"	"37.4"	"43.1"	"38.6"	"34.7"	"46.1"	"36.9"	"91.9"	"9.5"	"413.8"	"429.1"	"699.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ50"	"39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1"	"0.000"	""	"21"	"3"	"6"	"3"	"206"	"24.5"	"9.63"	"1661.93"	"14.34"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf09812"	"64976"	"ENSG00000185608"	"MRPL40"	"B3KVZ7; hsa:64976; O95134; Q9NQ50"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"22q11.2 copy number variation syndrome"	"4"	"0"	"38.3"	"30.7"	"34.7"	"35.3"	"41.5"	"36.2"	"92.6"	"4.0"	"579.4"	"580.1"	"1195.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14910"	"Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2"	"0.000"	""	"18"	"5"	"10"	"2"	"233"	"26.0"	"8.72"	"2221.97"	"14.33"	"5"	"4"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00595, Pf02828"	"8825"	"ENSG00000111052"	"LIN7A"	"A4FTY3; hsa:8825; O14910; Q147W1; Q6LES3; Q7LDS4"	"Assembly and cell surface presentation of NMDA receptors; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle"	""	"3"	"0"	"50.6"	"35.7"	"52.0"	"47.8"	"30.2"	"40.5"	"69.2"	"0.0"	"1094.2"	"1141.7"	"2276.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SY0"	"Integrator complex subunit 14 OS=Homo sapiens OX=9606 GN=INTS14 PE=1 SV=2"	"0.000"	""	"11"	"4"	"7"	"4"	"518"	"57.4"	"5.12"	"1133.88"	"14.31"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf13519, Pf19435, Pf20504"	"81556"	"ENSG00000138614"	"INTS14"	"B4DDI6; B4DVD5; hsa:81556; Q49AH8; Q96HX5; Q96SY0; Q9H0S5"	"RNA polymerase II transcribes snRNA genes"	"1p36 copy number variation syndrome"	"2"	"0"	"48.5"	"33.5"	"50.9"	"51.3"	"43.2"	"41.5"	"96.7"	"3.4"	"531.8"	"561.5"	"1146.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00568"	"Adenylate kinase isoenzyme 1 OS=Homo sapiens OX=9606 GN=AK1 PE=1 SV=3"	"0.000"	""	"20"	"3"	"5"	"3"	"194"	"21.6"	"8.63"	"714.12"	"14.30"	"2"	"3"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"203"	"ENSG00000106992"	"AK1"	"hsa:203; P00568; Q9BVK9; Q9UQC7"	"Interconversion of nucleotide di- and triphosphates"	""	"1"	"0"	"29.3"	"17.7"	"47.9"	"34.5"	"35.2"	"31.1"	"49.8"	"1.5"	"504.8"	"554.0"	"1768.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22392"	"Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1"	"0.000"	""	"27"	"3"	"6"	"3"	"152"	"17.3"	"8.41"	"1504.96"	"14.28"	"3"	"3"	"cell adhesion;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00334"	"4831; 654364"	"ENSG00000243678"	"NME2"	"A8MWA3; hsa:4831; hsa:654364; P22392; Q1WM23; Q6LCT6"	"Neutrophil degranulation; Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"Pyrimidine metabolism"	"5"	"0"	"133.2"	"119.5"	"184.5"	"138.6"	"120.3"	"119.3"	"202.4"	"0.0"	"1210.9"	"1260.8"	"2788.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY4"	"Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2"	"0.000"	""	"26"	"4"	"7"	"4"	"203"	"23.8"	"9.26"	"1048.84"	"14.26"	"3"	"4"	"other biological processes"	"nucleus"	"other molecular function"	"Pf11176"	"55319"	"ENSG00000198498"	"TMA16"	"hsa:55319; Q0P6E4; Q0P6J1; Q96EY4; Q9NUR7"	""	""	"0"	"0"	"48.3"	"35.8"	"64.2"	"64.5"	"60.4"	"54.6"	"190.7"	"5.9"	"1246.1"	"1195.6"	"2498.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX24"	"H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1"	"0.000"	""	"25"	"2"	"6"	"2"	"153"	"17.2"	"8.22"	"1729.46"	"14.23"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01248"	"55651"	"ENSG00000145912"	"NHP2"	"A6NKY8; hsa:55651; Q9NX24; Q9P095"	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	""	"2"	"0"	"46.6"	"39.0"	"37.5"	"32.2"	"28.9"	"32.9"	"88.8"	"0.0"	"557.2"	"540.1"	"1119.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61289"	"Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1"	"0.000"	""	"21"	"5"	"8"	"5"	"254"	"29.5"	"5.95"	"1016.73"	"14.15"	"3"	"5"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02251, Pf02252"	"10197"	"ENSG00000131467"	"PSME3"	"A8K9A3; hsa:10197; O35563; P61289; P97373; Q12920; Q13172; Q9BQD9"	"Regulation of expression of SLITs and ROBOs; Degradation of beta-catenin by the destruction complex; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Ubiquitin-dependent degradation of Cyclin D; Regulation of RUNX2 expression and activity; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling"	"Proteasome degradation"	"60"	"0"	"44.3"	"29.3"	"49.0"	"42.7"	"53.7"	"46.4"	"64.4"	"2.3"	"1326.1"	"1411.4"	"3021.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T200"	"Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1"	"0.000"	""	"3"	"5"	"9"	"5"	"1668"	"196.5"	"9.42"	"1612.99"	"14.13"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00642"	"23091"	"ENSG00000123200"	"ZC3H13"	"A2A323; hsa:23091; O94936; Q5T1Z9; Q5T200; Q7Z7J3; Q8NDT6; Q9H0L6"	""	""	"0"	"0"	"113.6"	"92.1"	"112.8"	"118.8"	"106.8"	"114.9"	"239.4"	"0.0"	"1202.9"	"1243.5"	"2242.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFP7"	"Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1"	"0.000"	""	"22"	"4"	"8"	"1"	"164"	"18.5"	"5.68"	"1696.63"	"14.13"	"3"	"3"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"170685"	"ENSG00000122824"	"NUDT10"	"A8K7D7; D3DX69; hsa:170685; Q86VK1; Q86VR0; Q8NFP7"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"52.9"	"43.7"	"76.5"	"65.9"	"38.0"	"61.2"	"127.3"	"1.4"	"519.3"	"492.6"	"1084.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43615"	"Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"3"	"452"	"51.3"	"8.32"	"1503.68"	"14.10"	"3"	"3"	"cell organization and biogenesis;transport"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf04280"	"10469"	"ENSG00000104980"	"TIMM44"	"A8K0R9; D6W664; hsa:10469; O43615; Q8N193"	"Mitochondrial protein import"	""	"1"	"0"	"17.8"	"16.3"	"31.0"	"23.5"	"21.3"	"27.3"	"48.2"	"9.2"	"555.1"	"509.1"	"1015.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13017"	"Rho GTPase-activating protein 5 OS=Homo sapiens OX=9606 GN=ARHGAP5 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1502"	"172.4"	"6.62"	"928.01"	"14.10"	"2"	"3"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"394"	"ENSG00000100852"	"ARHGAP5"	"A1L375; A1L376; A8KAA1; D3DS89; D3DS90; hsa:394; Q05BE8; Q05BU8; Q13017; Q59ER0; Q6DHZ3"	"RHOC GTPase cycle; RND2 GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"Focal adhesion"	"15"	"0"	"9.7"	"8.4"	"13.8"	"6.9"	"11.6"	"9.1"	"25.0"	"7.8"	"373.5"	"404.1"	"786.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30153"	"Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4"	"0.000"	""	"8"	"5"	"8"	"5"	"589"	"65.3"	"5.11"	"1703.13"	"14.09"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985"	"5518"	"ENSG00000105568"	"PPP2R1A"	"hsa:5518; P30153; Q13773; Q6ICQ3; Q96DH3"	"Regulation of TP53 Degradation; Separation of Sister Chromatids; RAF activation; Negative regulation of MAPK pathway; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"49"	"0"	"65.2"	"49.5"	"95.8"	"72.0"	"76.6"	"51.1"	"171.9"	"0.0"	"1286.0"	"1220.9"	"2744.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3Z3"	"Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"626"	"72.2"	"7.14"	"939.58"	"14.08"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01966, Pf07647"	"25939"	"ENSG00000101347"	"SAMHD1"	"B4E2A5; E1P5V2; hsa:25939; Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; Q9Y3Z3"	"Interferon alpha/beta signaling; Nucleotide catabolism"	""	"2"	"0"	"5.5"	"0.0"	"5.2"	"2.7"	"6.8"	"2.8"	"11.4"	"2.5"	"210.9"	"237.5"	"561.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95819"	"Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2"	"0.000"	""	"5"	"6"	"9"	"4"	"1239"	"142.0"	"7.46"	"1403.56"	"14.07"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00780"	"9448"	"ENSG00000071054"	"MAP4K4"	"E7ESS2; hsa:9448; O75172; O95819; Q9NST7"	"Oxidative Stress Induced Senescence"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"7"	"1"	"93.1"	"77.2"	"97.6"	"93.8"	"92.8"	"100.0"	"196.2"	"0.0"	"1619.6"	"1695.2"	"2694.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZT9"	"Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1"	"0.000"	""	"11"	"4"	"8"	"4"	"426"	"46.0"	"8.53"	"1535.88"	"14.01"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01753, Pf13640"	"54583"	"ENSG00000135766"	"EGLN1"	"hsa:54583; Q8N3M8; Q9BZS8; Q9BZT0; Q9GZT9"	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"Photodynamic therapy-induced HIF-1 survival signaling; Type 2 papillary renal cell carcinoma; Markers of kidney cell lineage"	"4"	"0"	"53.8"	"51.1"	"65.5"	"65.2"	"48.2"	"48.4"	"149.1"	"2.3"	"904.8"	"885.2"	"1588.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99569"	"Plakophilin-4 OS=Homo sapiens OX=9606 GN=PKP4 PE=1 SV=2"	"0.000"	""	"4"	"4"	"8"	"4"	"1192"	"131.8"	"8.94"	"1391.25"	"14.00"	"4"	"4"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"8502"	"ENSG00000144283"	"PKP4"	"hsa:8502; Q86W91; Q99569"	"Formation of the cornified envelope; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	""	"5"	"0"	"23.2"	"13.0"	"27.2"	"27.9"	"23.8"	"23.4"	"51.4"	"2.6"	"329.2"	"317.0"	"626.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92620"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2"	"0.000"	""	"4"	"3"	"5"	"3"	"1227"	"140.4"	"6.54"	"1236.61"	"13.98"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"9785"	"ENSG00000140829"	"DHX38"	"B4DVG8; D3DWS7; hsa:9785; O75212; Q92620; Q96HN7"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"5"	"0"	"49.5"	"43.6"	"59.5"	"50.9"	"53.6"	"47.7"	"76.6"	"1.1"	"450.6"	"458.5"	"976.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62906"	"60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2"	"0.000"	""	"22"	"5"	"11"	"5"	"217"	"24.8"	"9.94"	"2470.97"	"13.97"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00687"	"4736"	"ENSG00000198755"	"RPL10A"	"B2R801; hsa:4736; P52859; P53025; P62906; Q5TZT6; Q8J013"	"Selenocysteine synthesis; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"118.9"	"97.1"	"173.7"	"118.1"	"135.1"	"126.9"	"711.0"	"10.7"	"2503.4"	"2577.3"	"4513.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2U8"	"Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 GN=LEMD3 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"911"	"99.9"	"7.55"	"1500.23"	"13.96"	"3"	"3"	"other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf09402"	"23592"	"ENSG00000174106"	"LEMD3"	"hsa:23592; Q9NT47; Q9NYA5; Q9Y2U8"	"RAC1 GTPase cycle; RAC3 GTPase cycle; RND3 GTPase cycle; RND2 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; RND1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina"	"Envelope proteins and their potential roles in EDMD physiopathology"	"12"	"0"	"56.8"	"69.2"	"48.7"	"55.8"	"47.5"	"55.0"	"105.6"	"0.0"	"1126.5"	"1221.8"	"2283.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PD62"	"RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1"	"0.000"	""	"5"	"5"	"9"	"5"	"1173"	"133.4"	"6.77"	"1830.50"	"13.96"	"5"	"4"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13181"	"9646"	"ENSG00000198730"	"CTR9"	"D3DQV8; hsa:9646; Q15015; Q6PD62"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"Endoderm differentiation"	"5"	"0"	"243.0"	"237.5"	"148.6"	"180.3"	"182.1"	"185.6"	"324.2"	"8.7"	"1277.0"	"1437.5"	"2868.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27635"	"60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4"	"0.000"	""	"22"	"5"	"9"	"5"	"214"	"24.6"	"10.08"	"1903.64"	"13.93"	"5"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00252"	"100137264; 100146244; 100172946; 100415355; 100468790; 100724614; 100982236; 101083663; 101136536; 101344695; 101444008; 101539056; 101690567; 101867181; 101975002; 102028809; 102257301; 102442647; 102878669; 102890423; 102923570; 102957760; 103127392; 103211225; 103250904; 103731218; 104667036; 104872587; 105294701; 105302495; 105467951; 105521640; 105579731; 105727260; 105824536; 105867804; 106000161; 107160308; 108513162; 108518769; 109696857; 110954; 465944; 700795; 81764"	"ENSAMEG00000000227; ENSANAG00000036053; ENSCAFG00020009114; ENSCAFG00030015144; ENSCAFG00040021422; ENSCAFG00845028627; ENSCANG00000032226; ENSCATG00000030970; ENSCCAG00000024992; ENSCGRG00001008387; ENSCJAG00000011822; ENSCLAG00000003108; ENSCPOG00000002355; ENSECAG00000017154; ENSFCAG00000011395; ENSGGOG00000000131; ENSLCNG00005021252; ENSMFAG00000040824; ENSMLUG00000014337; ENSMMMG00000014279; ENSMMUG00000005494; ENSMNEG00000038094; ENSMPUG00000009320; ENSMUSG00000008682; ENSMUSG00000058443; ENSNGAG00000023746; ENSNLEG00000028143; ENSNVIG00000023818; ENSPANG00000008309; ENSPCOG00000027122; ENSPPAG00000034160; ENSPPYG00000020874; ENSPSMG00000015404; ENSPTIG00000005599; ENSPTRG00000043378; ENSRBIG00000042996; ENSRNOG00000056765; ENSRROG00000019247; ENSSSUG00005010590; ENSSTOG00000011857; ENSTGEG00000012563; ENSUAMG00000020454; ENSUMAG00000019583; ENSUPAG00010000252"	"LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"	"A0A091D943; A0A1S3APJ4; A0A1S3GPT7; A0A1U7SU42; A0A250YCK6; A0A286XQR8; A0A2I3FV08; A0A2J8IN69; A0A2J8RLU6; A0A2K5EV78; A0A2K5ILK8; A0A2K5LLF2; A0A2K5QER4; A0A2K5U275; A0A2K6D043; A0A2K6GRP4; A0A2K6MTH0; A0A2K6NK39; A0A2R9B361; A0A2Y9G5G6; A0A384DKX1; A0A3Q0CF07; A0A3Q7NJC4; A0A452S2Z9; A0A485PEW4; A0A667IJV2; A0A673U4F8; A0A6D2WIN2; A0A6D2XTB8; A0A6I9ME29; A0A6J0A9X4; A0A6J2E7G1; A0A6J3GU06; A0A6P3QFP2; A0A6P5P1X6; A0A6P6DLY1; A0A7J7YFN8; A0A7J8J7V5; A0A822A0T4; A0A8B7B976; A0A8B7FW91; A0A8C0K7J7; A0A8C0TBM4; A0A8C2LMI8; A0A8C2UVN1; A0A8C5ZPE8; A0A8C6S1T7; A0A8C7BXJ2; A0A8C8ZPD3; A0A8C9J452; A0A8D2F5T2; A0A8D2GF85; A0A8I3PXJ3; A0A8J8XDM4; A0A8M1M1S6; A0A9B0U593; A2AM97; A6KRS1; A9CB60; aju:106987320; aml:100468790; B0KWW6; B1MTV1; B3RFD9; C3PT02; cang:105521640; caty:105579731; ccan:109696857; cpoc:100724614; csyr:103250904; D3YC00; dnm:101444008; dord:106000161; ecb:100146244; F7AYR2; F7GKJ8; fca:101083663; G1PPT9; G2HFW2; G3S9Q9; G7Q3B3; ggo:101136536; H2PX84; I2CYS4; I3MI39; L5KDV0; L8Y8T7; M3WF14; M3YD39; mcal:110286529; mcc:700795; mcf:101867181; mlf:102442647; mmu:110954; mmur:105867804; mni:105467951; mpuf:101690567; myb:102257301; nsu:110578606; P45634; pale:102878669; pale:102890423; panu:100137264; pcoq:105824536; pps:100982236; ptg:102957760; ptr:465944; pvp:105294701; pvp:105302495; Q569M8; Q5M9K8; Q6PDV7; Q6ZWV3; rbb:108513162; rbb:108518769; rno:81764; rro:104667036; S7NR49; sara:101539056; tmu:101344695; umr:103679662; zca:113931110"	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"15"	"0"	"69.9"	"60.9"	"87.4"	"67.0"	"75.9"	"61.9"	"237.2"	"10.4"	"1109.7"	"1143.5"	"2363.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95239"	"Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3"	"0.000"	""	"3"	"4"	"7"	"4"	"1232"	"139.8"	"6.27"	"1116.74"	"13.93"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"24137"	"ENSG00000090889"	"KIF4A"	"B2R7V5; D3DVU4; hsa:24137; O95239; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"Retinoblastoma gene in cancer"	"5"	"0"	"50.1"	"36.4"	"54.3"	"55.4"	"62.9"	"69.4"	"111.0"	"11.1"	"1010.6"	"975.7"	"2071.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H223"	"EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1"	"0.000"	""	"11"	"5"	"6"	"4"	"541"	"61.1"	"6.76"	"705.12"	"13.92"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"30844"	"ENSG00000103966"	"EHD4"	"hsa:30844; Q9H223; Q9HAR1; Q9NZN2"	""	""	"0"	"1"	"41.7"	"31.9"	"50.4"	"35.9"	"44.6"	"44.4"	"88.6"	"9.3"	"1024.7"	"1094.8"	"2433.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15427"	"Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1"	"0.000"	""	"13"	"4"	"7"	"4"	"424"	"44.4"	"8.56"	"806.43"	"13.89"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"10262"	"ENSG00000143368"	"SF3B4"	"hsa:10262; Q15427; Q5SZ63"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing; 10q22q23 copy number variation"	"4"	"0"	"359.5"	"298.0"	"363.9"	"360.0"	"337.4"	"338.3"	"878.7"	"0.1"	"2022.2"	"1931.1"	"3809.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02040"	"A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2"	"0.000"	""	"7"	"5"	"7"	"5"	"695"	"80.7"	"9.73"	"978.36"	"13.89"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"8227"	"ENSG00000197976"	"AKAP17A"	"hsa:8227; Q02040; Q02832; Q2TB98; Q5JQ74; Q5JQ76; Q8N6U9"	""	""	"0"	"0"	"129.4"	"84.7"	"160.6"	"125.4"	"157.0"	"135.9"	"247.4"	"7.5"	"2371.5"	"2401.7"	"4610.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96J02"	"E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens OX=9606 GN=ITCH PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"3"	"903"	"102.7"	"6.30"	"1024.36"	"13.88"	"3"	"4"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf00397, Pf00632"	"83737"	"ENSG00000078747"	"ITCH"	"A6NEW4; B4E234; E1P5P3; F5H217; hsa:83737; O43584; Q5QP37; Q5TEL0; Q96F66; Q96J02; Q9BY75; Q9H451; Q9H4U5"	"Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Activated NOTCH1 Transmits Signal to the Nucleus; Regulation of necroptotic cell death; NOD1/2 Signaling Pathway; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses; Downregulation of ERBB4 signaling"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; 10q11.21q11.23 copy number variation syndrome; Notch signaling pathway"	"15"	"1"	"50.9"	"24.0"	"59.0"	"51.8"	"53.0"	"45.1"	"81.4"	"3.5"	"676.7"	"723.5"	"1579.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22061"	"Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4"	"0.000"	""	"11"	"2"	"8"	"2"	"227"	"24.6"	"7.21"	"1995.69"	"13.86"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01135"	"5110"	"ENSG00000120265"	"PCMT1"	"A8K109; hsa:5110; J3KP72; P22061; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061; Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03"	"Protein repair"	"Primary ovarian insufficiency"	"2"	"0"	"248.1"	"230.2"	"254.2"	"243.2"	"244.6"	"247.9"	"344.8"	"0.0"	"731.1"	"746.3"	"910.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JM3"	"Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2"	"0.000"	""	"8"	"5"	"8"	"5"	"812"	"89.0"	"8.44"	"1646.01"	"13.84"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"283489"	"ENSG00000198824"	"CHAMP1"	"B3KU06; hsa:283489; Q6P181; Q8NC88; Q96JM3; Q9BST0"	""	""	"0"	"0"	"124.6"	"86.7"	"111.1"	"116.2"	"99.7"	"97.3"	"253.9"	"6.2"	"1343.9"	"1348.5"	"2860.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP8"	"Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1"	"0.000"	""	"28"	"4"	"7"	"4"	"204"	"22.6"	"9.45"	"1179.16"	"13.82"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf09282"	"84305"	"ENSG00000170473"	"PYM1"	"B6ZDM5; hsa:84305; Q8IXJ8; Q8N8E7; Q9BRP8"	""	"TAR syndrome"	"1"	"0"	"38.2"	"41.4"	"33.3"	"44.0"	"35.8"	"41.9"	"78.6"	"1.4"	"522.4"	"541.5"	"964.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBD5"	"Origin recognition complex subunit 3 OS=Homo sapiens OX=9606 GN=ORC3 PE=1 SV=1"	"0.000"	""	"6"	"4"	"7"	"3"	"711"	"82.2"	"7.61"	"1327.39"	"13.80"	"3"	"4"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07034, Pf18137, Pf19675"	"23595"	"ENSG00000135336"	"ORC3"	"A2A2T5; B4E025; hsa:23595; Q13565; Q53GY6; Q5T159; Q6IUY7; Q86TN5; Q9UBD5; Q9UG44; Q9UNT6"	"Orc1 removal from chromatin; Assembly of the ORC complex at the origin of replication; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; CDC6 association with the ORC:origin complex"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"10"	"1"	"58.2"	"43.9"	"70.1"	"61.1"	"67.7"	"68.3"	"112.9"	"1.6"	"986.2"	"999.6"	"2050.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95104"	"SR-related and CTD-associated factor 4 OS=Homo sapiens OX=9606 GN=SCAF4 PE=1 SV=3"	"0.000"	""	"4"	"3"	"8"	"3"	"1147"	"125.8"	"9.55"	"1246.44"	"13.76"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf04818"	"57466"	"ENSG00000156304"	"SCAF4"	"C9JLZ0; hsa:57466; O95104; Q0P5W8; Q6P1M5; Q8N3I8; Q9UFM1; Q9ULP8"	""	""	"0"	"0"	"94.8"	"65.6"	"109.7"	"86.7"	"88.8"	"86.6"	"138.7"	"0.8"	"1529.3"	"1480.3"	"2716.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P20290"	"Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1"	""	""	"21"	"3"	"3"	"3"	"206"	"22.2"	"9.38"	""	"13.75"	""	"3"	"transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	""	"Pf01849"	"689"	"ENSG00000145741"	"BTF3"	"A8K510; hsa:689; P20290; Q13893; Q76M56"	""	"Orexin receptor pathway"	"1"	"0"	"11.1"	"12.2"	"12.3"	"10.5"	"15.5"	"9.1"	"14.5"	"2.6"	"652.7"	"687.5"	"2333.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4KMP7"	"TBC1 domain family member 10B OS=Homo sapiens OX=9606 GN=TBC1D10B PE=1 SV=3"	"0.000"	""	"7"	"3"	"5"	"3"	"808"	"87.1"	"9.19"	"681.49"	"13.72"	"2"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol"	"enzyme regulator activity"	"Pf00566"	"26000"	"ENSG00000169221"	"TBC1D10B"	"B9A6L0; hsa:26000; Q4KMP7; Q6IN54; Q6P530; Q71RG7; Q86VC5; Q9H8Z2; Q9NUN6; Q9UFP2"	"TBC/RABGAPs"	""	"1"	"0"	"29.8"	"25.8"	"43.2"	"39.3"	"32.7"	"152.8"	"70.2"	"7.7"	"396.0"	"376.5"	"745.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49755"	"Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2"	"0.000"	""	"22"	"4"	"7"	"4"	"219"	"25.0"	"7.44"	"1091.88"	"13.72"	"3"	"4"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf01105"	"10972"	"ENSG00000170348"	"TMED10"	"B2R605; hsa:10972; P49755; Q15602; Q16536; Q86TC2; Q86TS5"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Cargo concentration in the ER"	"mRNA processing; 5q35 copy number variation"	"6"	"0"	"15.7"	"8.7"	"21.1"	"19.4"	"16.8"	"20.3"	"37.4"	"2.0"	"721.3"	"761.7"	"1471.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXB1"	"DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"793"	"91.0"	"7.18"	"850.73"	"13.64"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00085, Pf00226"	"54431"	"ENSG00000077232"	"DNAJC10"	"hsa:54431; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8IXB1; Q8NC82; Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6"	""	""	"0"	"0"	"48.0"	"42.7"	"57.6"	"40.6"	"51.3"	"49.6"	"93.8"	"0.6"	"531.3"	"536.8"	"1151.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13619"	"Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3"	"0.000"	""	"6"	"5"	"10"	"1"	"759"	"87.6"	"8.13"	"1525.35"	"13.63"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8451"	"ENSG00000139842"	"CUL4A"	"A2A2W2; hsa:8451; O75834; Q13619; Q589T6; Q5TC62; Q6UP08; Q9UP17"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"Hippo-Merlin signaling dysregulation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"13"	"0"	"45.9"	"37.4"	"37.9"	"40.9"	"43.2"	"42.1"	"47.2"	"0.0"	"504.5"	"532.3"	"965.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A0FGR8"	"Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1"	"0.000"	""	"5"	"4"	"8"	"4"	"921"	"102.3"	"9.26"	"1398.96"	"13.61"	"4"	"4"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00168, Pf17047"	"57488"	"ENSG00000117868"	"ESYT2"	"A0FGR8; A4D229; hsa:57488; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47; Q9ULJ2"	"Glycosphingolipid metabolism"	""	"1"	"0"	"27.8"	"26.5"	"34.1"	"43.6"	"69.3"	"92.3"	"125.9"	"4.3"	"652.3"	"662.5"	"1007.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01780"	"Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"885"	"100.8"	"8.46"	"1273.16"	"13.61"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00570, Pf01612, Pf08066"	"5394"	"ENSG00000171824"	"EXOSC10"	"B1AKQ0; B1AKQ1; hsa:5394; Q01780; Q15158"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"166.3"	"124.6"	"193.9"	"235.4"	"138.7"	"145.6"	"414.6"	"1.1"	"1360.7"	"1311.4"	"2496.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZ29"	"Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9 PE=1 SV=2"	"0.000"	""	"3"	"4"	"8"	"4"	"2069"	"236.3"	"7.49"	"1384.52"	"13.58"	"4"	"4"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"23348"	"ENSG00000088387"	"DOCK9"	"B3KX25; E9PFM9; hsa:23348; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25; Q9BZ26; Q9BZ27; Q9BZ28; Q9BZ29; Q9UPU4"	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	""	"3"	"0"	"31.2"	"25.8"	"37.7"	"28.7"	"38.7"	"43.0"	"143.6"	"2.3"	"774.6"	"730.6"	"1134.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY42"	"Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3"	"0.000"	""	"16"	"4"	"7"	"4"	"306"	"33.9"	"8.59"	"1575.09"	"13.55"	"4"	"3"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04641"	"51507"	"ENSG00000022277"	"RTF2"	"E1P5Z9; hsa:51507; Q9BY42; Q9BYL7; Q9HCV9; Q9NX29; Q9NZZ8; Q9P002; Q9UHW3"	""	""	"0"	"0"	"89.8"	"66.1"	"88.8"	"97.7"	"86.2"	"102.5"	"188.9"	"0.5"	"1115.8"	"1113.3"	"2060.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEM1"	"Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3"	"0.000"	""	"2"	"4"	"7"	"4"	"1887"	"205.0"	"6.81"	"1149.37"	"13.49"	"3"	"4"	"transport"	"other membranes;ER/Golgi;nucleus"	""	"Pf02368"	"23225"	"ENSG00000132182"	"NUP210"	"A6NN56; hsa:23225; O94980; Q6NXG6; Q8NBJ1; Q8TEM1; Q9H6C8; Q9UFP3"	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; HCMV Late Events; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"28"	"0"	"42.0"	"16.4"	"16.7"	"41.3"	"54.3"	"46.2"	"71.0"	"1.3"	"884.8"	"1001.2"	"2221.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62834"	"Ras-related protein Rap-1A OS=Homo sapiens OX=9606 GN=RAP1A PE=1 SV=1"	"0.000"	""	"20"	"3"	"6"	"3"	"184"	"21.0"	"6.67"	"773.92"	"13.47"	"2"	"3"	"cell-cell signaling;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"5906"	"ENSG00000116473"	"RAP1A"	"hsa:5906; P10113; P62834"	"Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; ARMS-mediated activation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Brain-derived neurotrophic factor (BDNF) signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Leukocyte-intrinsic Hippo pathway functions; DNA repair pathways, full network; GDNF signaling; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"34"	"0"	"72.1"	"66.3"	"61.5"	"73.2"	"71.6"	"54.6"	"145.7"	"1.8"	"943.6"	"921.8"	"1742.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH3"	"Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1"	"0.000"	""	"9"	"3"	"8"	"3"	"380"	"42.1"	"5.63"	"1271.53"	"13.44"	"3"	"3"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"348995"	"ENSG00000120253"	"NUP43"	"B4E2F0; hsa:348995; Q8NFH3; Q9H8S0"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	""	"35"	"0"	"53.4"	"34.6"	"61.9"	"52.0"	"69.8"	"54.1"	"101.0"	"2.3"	"435.0"	"395.2"	"723.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57772"	"Selenocysteine-specific elongation factor OS=Homo sapiens OX=9606 GN=EEFSEC PE=1 SV=4"	"0.000"	""	"7"	"4"	"6"	"4"	"596"	"65.3"	"8.35"	"860.46"	"13.42"	"2"	"4"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"60678"	"ENSG00000132394; ENSG00000284869"	"EEFSEC"	"hsa:60678; P57772; Q96HZ6"	"Selenocysteine synthesis"	""	"1"	"0"	"34.2"	"19.6"	"45.1"	"35.8"	"43.5"	"46.5"	"121.7"	"1.3"	"1450.6"	"1458.3"	"2338.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13492"	"Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"652"	"70.7"	"7.90"	"916.34"	"13.39"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf07651"	"8301"	"ENSG00000073921"	"PICALM"	"B4DTM3; E9PN05; F8VPG7; hsa:8301; O60700; Q13492; Q4LE54; Q6GMQ6; Q86XZ9"	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis; RND3 GTPase cycle"	""	"4"	"0"	"58.1"	"44.8"	"73.9"	"70.4"	"71.6"	"108.0"	"188.2"	"4.0"	"1155.7"	"1126.5"	"1895.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15003"	"Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3"	"0.000"	""	"5"	"3"	"8"	"3"	"741"	"82.5"	"5.06"	"1420.33"	"13.39"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05786"	"23397"	"ENSG00000121152"	"NCAPH"	"B4E189; hsa:23397; Q15003; Q8TB87"	"Condensation of Prometaphase Chromosomes"	"2q11.2 copy number variation syndrome"	"2"	"0"	"86.7"	"82.1"	"89.0"	"78.6"	"80.9"	"114.4"	"160.8"	"4.1"	"682.3"	"681.1"	"1415.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01130"	"Serine/arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4"	"0.000"	""	"17"	"4"	"8"	"4"	"221"	"25.5"	"11.85"	"1204.17"	"13.35"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6427"	"ENSG00000161547"	"SRSF2"	"B3KWD5; B4DN89; H0YG49; hsa:6427; Q01130"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"mRNA processing"	"7"	"0"	"279.1"	"217.0"	"207.6"	"242.7"	"198.9"	"219.2"	"467.0"	"2.2"	"1154.8"	"1133.2"	"2492.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95757"	"Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3"	"0.000"	""	"6"	"3"	"4"	"2"	"839"	"94.5"	"5.88"	"420.25"	"13.33"	"1"	"3"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00012"	"22824"	"ENSG00000164070"	"HSPA4L"	"A2ICT2; hsa:22824; O95757; Q4W5M5; Q8IWA2"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"25.2"	"19.5"	"26.1"	"28.4"	"33.2"	"22.9"	"52.6"	"3.2"	"260.7"	"267.3"	"485.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51003"	"Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4"	""	""	"6"	"4"	"4"	"4"	"745"	"82.8"	"7.37"	""	"13.31"	""	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"10914"	"ENSG00000090060"	"PAPOLA"	"hsa:10914; P51003; Q86SX4; Q86TV0; Q8IYF5; Q9BVU2"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"50.5"	"26.1"	"62.5"	"54.4"	"66.9"	"50.5"	"67.2"	"1.9"	"1063.4"	"1024.1"	"2606.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13547"	"Histone deacetylase 1 OS=Homo sapiens OX=9606 GN=HDAC1 PE=1 SV=1"	"0.000"	""	"11"	"4"	"8"	"1"	"482"	"55.1"	"5.48"	"1609.07"	"13.28"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3065"	"ENSG00000116478"	"HDAC1"	"hsa:3065; Q13547; Q92534"	"Potential therapeutics for SARS; SUMOylation of chromatin organization proteins; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Formation of the beta-catenin:TCF transactivating complex; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of PTEN gene transcription; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Estrogen-dependent gene expression; MECP2 regulates transcription of neuronal ligands; Factors involved in megakaryocyte development and platelet production; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Downregulation of SMAD2/3:SMAD4 transcriptional activity; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; G1/S-Specific Transcription; Regulation of TP53 Activity through Acetylation; Transcription of E2F targets under negative control by DREAM complex; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; MECP2 regulates neuronal receptors and channels; Repression of WNT target genes; Loss of MECP2 binding ability to 5mC-DNA"	"Androgen receptor signaling pathway; Energy metabolism; Cell cycle; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Neural crest differentiation; Retinoblastoma gene in cancer; Notch signaling; Apoptosis-related network due to altered Notch3 in ovarian cancer; Initiation of transcription and translation elongation at the HIV-1 LTR; MECP2 and associated Rett syndrome; IL6 signaling pathway; Valproic acid pathway; VEGFA-VEGFR2 signaling; Ethanol effects on histone modifications; Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; Transcription co-factors SKI and SKIL protein partners; Overlap between signal transduction pathways contributing to LMNA laminopathies; Opioid receptor pathways; 15q11q13 copy number variation; Notch signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"54"	"3"	"143.0"	"111.5"	"141.3"	"124.0"	"131.1"	"109.4"	"261.3"	"3.9"	"1276.7"	"1301.8"	"2811.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULW0"	"Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2"	"0.000"	""	"10"	"6"	"9"	"6"	"747"	"85.6"	"9.23"	"2605.76"	"13.28"	"6"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06886, Pf09041, Pf12214"	"22974"	"ENSG00000088325"	"TPX2"	"hsa:22974; Q96RR5; Q9H1R4; Q9NRA3; Q9UFN9; Q9UL00; Q9ULW0; Q9Y2M1"	"AURKA Activation by TPX2; Regulation of TP53 Activity through Phosphorylation"	"Gastric cancer network 1"	"3"	"0"	"255.6"	"195.1"	"279.2"	"269.4"	"244.1"	"225.1"	"648.9"	"8.8"	"2606.8"	"2507.4"	"5221.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27708"	"CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3"	"0.000"	""	"2"	"4"	"8"	"4"	"2225"	"242.8"	"6.46"	"1390.55"	"13.24"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00117, Pf00185, Pf00988, Pf01979, Pf02142, Pf02729, Pf02786, Pf02787"	"790"	"ENSG00000084774"	"CAD"	"D6W552; hsa:790; P27708; Q6P0Q0; Q96CK3"	"Pyrimidine biosynthesis"	"Endothelin pathways; Amino acid metabolism; Pyrimidine metabolism"	"4"	"0"	"53.2"	"39.7"	"67.2"	"42.7"	"53.9"	"53.4"	"75.5"	"1.2"	"630.3"	"659.5"	"1354.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96019"	"Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1"	"0.000"	""	"9"	"3"	"6"	"3"	"429"	"47.4"	"5.60"	"1201.66"	"13.23"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00022"	"86"	"ENSG00000136518"	"ACTL6A"	"B3KMN1; D3DNR9; hsa:86; O96019; Q8TAE5; Q9BVS8; Q9H0W6"	"RMTs methylate histone arginines; UCH proteinases; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"Androgen receptor network in prostate cancer; Gastric cancer network 1; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"10"	"0"	"123.9"	"122.1"	"158.3"	"151.4"	"146.1"	"127.7"	"205.7"	"0.0"	"1027.0"	"1068.7"	"2619.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15370"	"Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1"	"0.000"	""	"38"	"3"	"4"	"3"	"118"	"13.1"	"4.88"	"336.46"	"13.22"	"1"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240"	"6923"	"ENSG00000103363"	"ELOB"	"B7WPD3; hsa:6923; Q15370"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; Modulators of TCR signaling and T cell activation"	"21"	"0"	"88.6"	"82.5"	"78.1"	"92.7"	"91.7"	"82.7"	"130.0"	"3.3"	"1132.4"	"1128.8"	"2354.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0S4"	"Probable ATP-dependent RNA helicase DDX47 OS=Homo sapiens OX=9606 GN=DDX47 PE=1 SV=1"	"0.000"	""	"11"	"4"	"6"	"4"	"455"	"50.6"	"9.10"	"1884.43"	"13.20"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51202"	"ENSG00000213782"	"DDX47"	"B3KXP4; G5E955; hsa:51202; Q96GM0; Q96NV8; Q9H0S4; Q9UI98"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"34.6"	"25.8"	"43.3"	"30.9"	"28.5"	"41.5"	"126.0"	"5.5"	"493.7"	"499.4"	"1099.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99575"	"Ribonucleases P/MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1024"	"114.6"	"9.22"	"266.50"	"13.18"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06978, Pf08170"	"10940"	"ENSG00000104356"	"POP1"	"A8K5W9; hsa:10940; Q15037; Q99575"	"tRNA processing in the nucleus"	""	"1"	"0"	"727.1"	"129.6"	"1443.3"	"986.0"	"943.4"	"585.9"	"697.7"	"0.0"	"1367.3"	"960.9"	"2948.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62851"	"40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1"	"0.000"	""	"28"	"4"	"8"	"4"	"125"	"13.7"	"10.11"	"886.75"	"13.16"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03297"	"6230"	"ENSG00000118181; ENSG00000280831"	"RPS25"	"B2R4M7; hsa:6230; P25111; P62851"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Peptide chain elongation; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"55.3"	"46.9"	"64.3"	"61.8"	"70.2"	"62.1"	"156.6"	"2.9"	"1726.0"	"2101.7"	"4659.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCC0"	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1"	"0.000"	""	"10"	"5"	"9"	"5"	"563"	"61.3"	"7.68"	"1781.45"	"13.13"	"5"	"4"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01039"	"64087"	"ENSG00000131844"	"MCCC2"	"A6NIY9; hsa:64087; Q96C27; Q9HCC0; Q9Y4L7"	"Biotin transport and metabolism; Branched-chain amino acid catabolism; Defective HLCS causes multiple carboxylase deficiency"	""	"3"	"0"	"210.9"	"171.8"	"163.6"	"172.1"	"175.2"	"173.4"	"433.9"	"6.8"	"1626.5"	"1638.0"	"2781.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P80723"	"Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2"	"0.000"	""	"15"	"2"	"4"	"2"	"227"	"22.7"	"4.63"	"459.02"	"13.13"	"1"	"2"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05466"	"10409"	"ENSG00000176788"	"BASP1"	"B4DJA8; D3DTD5; hsa:10409; O43596; P80723; Q5U0S0; Q9BWA5"	"RHOF GTPase cycle"	""	"1"	"0"	"58.1"	"52.4"	"41.3"	"47.8"	"49.5"	"50.2"	"95.3"	"5.0"	"687.4"	"854.5"	"1311.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92665"	"28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3"	"0.000"	""	"14"	"5"	"9"	"5"	"395"	"45.3"	"9.29"	"1604.26"	"13.12"	"5"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf15433"	"10240"	"ENSG00000102738"	"MRPS31"	"B2RCS3; hsa:10240; Q5VYC8; Q8WTV8; Q92665"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"185.3"	"152.9"	"175.5"	"151.1"	"183.5"	"191.3"	"313.1"	"3.3"	"1299.3"	"1279.9"	"2767.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14745"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF1 OS=Homo sapiens OX=9606 GN=SLC9A3R1 PE=1 SV=4"	"0.000"	""	"13"	"4"	"7"	"4"	"358"	"38.8"	"5.77"	"947.14"	"13.12"	"3"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;transporter activity;cytoskeletal activity;other molecular function"	"Pf00595, Pf09007"	"9368"	"ENSG00000109062"	"NHERF1"	"B3KY21; hsa:9368; O14745; O43552; Q86WQ5"	""	"TAR syndrome"	"1"	"0"	"15.7"	"12.4"	"25.4"	"24.7"	"20.7"	"18.4"	"56.2"	"9.8"	"721.5"	"719.6"	"1474.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02880"	"DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3"	"0.000"	""	"4"	"4"	"7"	"3"	"1626"	"183.2"	"8.00"	"1141.50"	"13.10"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00204, Pf00521, Pf01751, Pf02518, Pf08070, Pf16898"	"7155"	"ENSG00000077097"	"TOP2B"	"hsa:7155; Q02880; Q13600; Q9UMG8; Q9UQP8"	"SUMOylation of DNA replication proteins"	""	"1"	"1"	"65.5"	"49.1"	"71.1"	"54.5"	"57.0"	"68.5"	"150.2"	"2.7"	"956.4"	"989.0"	"2574.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62841"	"40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2"	"0.000"	""	"37"	"3"	"6"	"3"	"145"	"17.0"	"10.39"	"732.85"	"13.10"	"2"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00203"	"6209"	"ENSG00000115268"	"RPS15"	"A5D8V9; hsa:6209; P11174; P62841; Q3KRA1; Q9UDC2"	"Regulation of expression of SLITs and ROBOs; SARS-CoV-2 modulates host translation machinery; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"77.3"	"63.1"	"107.6"	"82.6"	"95.1"	"92.9"	"210.2"	"5.9"	"1131.2"	"1214.0"	"2167.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q32MZ4"	"Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2"	"0.000"	""	"5"	"4"	"6"	"4"	"808"	"89.2"	"4.65"	"776.56"	"13.09"	"2"	"4"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09738"	"9208"	"ENSG00000124831"	"LRRFIP1"	"E9PGZ2; hsa:9208; O75766; O75799; Q32MZ4; Q32MZ5; Q53T49; Q6PKG2; Q9Y607"	"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"IL-18 signaling pathway; 2q37 copy number variation syndrome"	"5"	"0"	"63.7"	"38.5"	"59.5"	"60.7"	"56.5"	"58.2"	"89.6"	"2.6"	"1322.4"	"1344.9"	"3113.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15014"	"Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"288"	"32.3"	"9.72"	"1397.30"	"13.02"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf05712"	"9643"	"ENSG00000123562"	"MORF4L2"	"B3KP92; D3DXA5; hsa:9643; Q15014; Q567V0; Q8J026"	"HATs acetylate histones"	""	"1"	"0"	"61.4"	"43.1"	"62.2"	"56.4"	"51.4"	"55.5"	"172.7"	"3.7"	"857.6"	"868.2"	"1904.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13825"	"Methylglutaconyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=AUH PE=1 SV=1"	"0.000"	""	"13"	"4"	"8"	"4"	"339"	"35.6"	"9.48"	"1423.69"	"13.00"	"4"	"4"	"other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00378"	"549"	"ENSG00000148090"	"AUH"	"B1ALV7; B1ALV8; hsa:549; Q13825; Q8WUE4"	"Branched-chain amino acid catabolism"	"Amino acid metabolism"	"2"	"0"	"61.2"	"66.3"	"108.4"	"88.4"	"62.3"	"92.1"	"209.2"	"5.9"	"1156.3"	"1149.8"	"2560.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H5V9"	"UPF0428 protein CXorf56 OS=Homo sapiens OX=9606 GN=CXorf56 PE=1 SV=1"	"0.000"	""	"17"	"5"	"8"	"5"	"222"	"25.6"	"8.73"	"1621.86"	"13.00"	"5"	"3"	"cell organization and biogenesis;transport"	"cytoskeleton;nucleus;other cell component"	""	""	"63932"	"ENSG00000018610"	"STEEP1"	"A8MPX7; B4DQN2; D3DWH9; F5GWL7; hsa:63932; O43351; Q9H5V9"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"256.6"	"216.7"	"278.1"	"228.8"	"200.4"	"242.5"	"486.2"	"0.0"	"2118.1"	"2096.8"	"3882.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NZY4"	"Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2"	"0.000"	""	"5"	"2"	"6"	"2"	"707"	"78.5"	"4.87"	"1404.23"	"12.98"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf04046"	"55596"	"ENSG00000033030"	"ZCCHC8"	"hsa:55596; Q6NZY4; Q7L2P6; Q8N2K5; Q96SK7; Q9NSS2; Q9NSS3"	""	""	"0"	"0"	"87.4"	"55.2"	"89.9"	"81.3"	"74.0"	"88.3"	"134.7"	"1.7"	"396.0"	"337.7"	"761.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09884"	"DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2"	"0.000"	""	"3"	"4"	"6"	"4"	"1462"	"165.8"	"5.85"	"556.36"	"12.96"	"2"	"4"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08996, Pf12254"	"5422"	"ENSG00000101868"	"POLA1"	"hsa:5422; P09884; Q86UQ7"	"Activation of the pre-replicative complex; Defective pyroptosis; G1/S-Specific Transcription; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication"	"13"	"0"	"43.9"	"35.5"	"57.2"	"63.6"	"51.3"	"50.3"	"105.6"	"12.6"	"1177.5"	"1198.4"	"2675.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95785"	"Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"2"	"1651"	"178.6"	"6.86"	"1106.83"	"12.95"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"58525"	"ENSG00000011451"	"WIZ"	"B3KVH1; B7ZM82; hsa:58525; M0QY21; O95785; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; Q9NPT1"	""	""	"0"	"0"	"14.5"	"9.8"	"12.2"	"10.7"	"9.1"	"13.2"	"28.2"	"1.6"	"82.7"	"78.0"	"196.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5QJE6"	"Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"756"	"84.4"	"6.16"	"1182.61"	"12.92"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf08698"	"30836"	"ENSG00000067334"	"DNTTIP2"	"hsa:30836; Q12987; Q53H59; Q5QJE6; Q5TFJ4; Q6TLI0; Q76MJ8; Q86WX9"	""	""	"0"	"0"	"62.4"	"51.8"	"62.5"	"55.7"	"61.7"	"61.9"	"108.7"	"1.3"	"555.1"	"524.8"	"1117.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52789"	"Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2"	"0.000"	""	"5"	"5"	"7"	"3"	"917"	"102.3"	"6.05"	"1000.80"	"12.91"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3099"	"ENSG00000159399"	"HK2"	"D6W5J2; hsa:3099; P52789; Q8WU87; Q9UN82"	"Glycolysis"	"Clear cell renal cell carcinoma pathways; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"7"	"0"	"70.0"	"58.9"	"60.2"	"70.5"	"56.1"	"72.6"	"103.4"	"1.4"	"967.8"	"1010.6"	"1889.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35222"	"Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1"	"0.000"	""	"7"	"5"	"10"	"4"	"781"	"85.4"	"5.86"	"1775.73"	"12.90"	"5"	"5"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"1499"	"ENSG00000168036"	"CTNNB1"	"A8K1L7; hsa:1499; P35222; Q8NEW9; Q8NI94; Q9H391"	"Somitogenesis; Deactivation of the beta-catenin transactivating complex; InlA-mediated entry of Listeria monocytogenes into host cells; RHO GTPases activate IQGAPs; Formation of paraxial mesoderm; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Formation of axial mesoderm; Myogenesis; Transcriptional Regulation by VENTX; Ca2+ pathway; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Cardiogenesis; Germ layer formation at gastrulation; Formation of definitive endoderm; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; Binding of TCF/LEF:CTNNB1 to target gene promoters; RUNX3 regulates WNT signaling; Apoptotic cleavage of cell adhesion  proteins; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Heart development; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Gastric cancer network 2; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Endoderm differentiation; Ectoderm differentiation; Extracellular vesicle-mediated signaling in recipient cells; Focal adhesion; Ectoderm differentiation; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; OSX and miRNAs in tooth development; Wnt signaling pathway and pluripotency; PTF1A related regulatory pathway; Wnt signaling in kidney disease; Endometrial cancer; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; Osteoblast differentiation and related diseases; TGF-beta receptor signaling in skeletal dysplasias; Genes controlling nephrogenesis; GDNF/RET signaling axis; Mammalian disorder of sexual development; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; 1q21.1 copy number variation syndrome; 7q11.23 copy number variation syndrome; Development of ureteric collection system; Pleural mesothelioma; Alzheimer's disease; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; TROP2 regulatory signaling; 8p23.1 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response (only ATM dependent)"	"96"	"1"	"147.5"	"128.6"	"151.6"	"141.5"	"131.1"	"121.6"	"286.3"	"4.9"	"1318.3"	"1402.7"	"2528.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23378"	"Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2"	"0.000"	""	"6"	"4"	"7"	"4"	"1020"	"112.7"	"7.11"	"847.20"	"12.90"	"3"	"4"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01212, Pf02347"	"2731"	"ENSG00000178445"	"GLDC"	"hsa:2731; P23378; Q2M2F8"	"Glycine degradation"	"Metabolic Epileptic Disorders"	"2"	"0"	"39.0"	"34.7"	"44.2"	"39.3"	"49.1"	"39.2"	"88.2"	"5.0"	"795.2"	"764.1"	"1374.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVS2"	"Malonyl-CoA-acyl carrier protein transacylase, mitochondrial OS=Homo sapiens OX=9606 GN=MCAT PE=1 SV=2"	"0.000"	""	"11"	"3"	"5"	"3"	"390"	"42.9"	"8.72"	"682.84"	"12.89"	"2"	"3"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00698"	"27349"	"ENSG00000100294"	"MCAT"	"B0QY72; hsa:27349; O95510; O95511; Q8IVS2"	"Mitochondrial Fatty Acid Beta-Oxidation"	"Mitochondrial fatty acid synthesis pathway"	"2"	"0"	"29.0"	"22.5"	"38.1"	"34.7"	"33.3"	"30.7"	"70.9"	"1.8"	"803.9"	"818.5"	"1647.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEA8"	"D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2"	"0.000"	""	"13"	"3"	"5"	"3"	"209"	"23.4"	"8.24"	"1037.26"	"12.88"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02580"	"92675"	"ENSG00000125821"	"DTD1"	"A8K5X5; D3DW37; hsa:92675; Q496D1; Q5W184; Q8TEA8; Q8WXU8; Q9BW67; Q9H464; Q9H474"	""	""	"0"	"0"	"38.6"	"28.4"	"40.0"	"42.9"	"41.6"	"44.8"	"53.2"	"0.9"	"958.2"	"1147.5"	"2646.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAW4"	"Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"1339"	"151.0"	"4.82"	"519.27"	"12.85"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus"	"nucleic acid binding activity;other molecular function"	""	"63967"	"ENSG00000092853"	"CLSPN"	"A6NFL4; hsa:63967; Q1RMC6; Q2KHM3; Q5VYG0; Q6P6H5; Q8IWI1; Q9HAW4"	"Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Ub-specific processing proteases; Apoptotic cleavage of cellular proteins"	""	"4"	"0"	"53.9"	"40.2"	"39.9"	"47.9"	"44.0"	"40.7"	"63.3"	"2.2"	"351.6"	"385.1"	"697.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEY8"	"Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2"	"0.000"	""	"12"	"5"	"8"	"5"	"458"	"52.7"	"9.11"	"989.51"	"12.83"	"3"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf11488"	"51535"	"ENSG00000134283"	"PPHLN1"	"E9PAX8; hsa:51535; Q86YT2; Q8IXN3; Q8NEY8; Q8TB09; Q96NB9; Q9NXL4; Q9P0P6; Q9P0R9"	""	""	"0"	"0"	"378.5"	"296.6"	"322.9"	"341.6"	"314.3"	"333.0"	"741.0"	"2.3"	"1853.4"	"1848.1"	"3475.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B9"	"RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2"	"0.000"	""	"11"	"2"	"4"	"2"	"282"	"31.5"	"5.52"	"412.17"	"12.82"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	""	"Pf07890"	"51018"	"ENSG00000067533"	"RRP15"	"hsa:51018; Q9Y3B9"	""	""	"0"	"0"	"31.7"	"26.8"	"35.8"	"39.9"	"40.8"	"42.3"	"120.0"	"2.0"	"326.1"	"300.1"	"553.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13425"	"Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1"	"0.000"	""	"6"	"3"	"9"	"3"	"540"	"57.9"	"8.82"	"1861.84"	"12.81"	"3"	"3"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf18012"	"6645"	"ENSG00000168807"	"SNTB2"	"hsa:6645; Q13425; Q9BY09"	""	""	"0"	"0"	"99.4"	"70.6"	"109.0"	"92.7"	"91.9"	"103.1"	"173.7"	"0.6"	"1479.0"	"1511.6"	"2986.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95391"	"Pre-mRNA-splicing factor SLU7 OS=Homo sapiens OX=9606 GN=SLU7 PE=1 SV=2"	"0.000"	""	"7"	"3"	"4"	"3"	"586"	"68.3"	"7.14"	"264.67"	"12.80"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11708"	"10569"	"ENSG00000164609"	"SLU7"	"D3DQK2; hsa:10569; O95391; Q3LUJ0; Q3LUJ1; Q6RXQ5; Q96FM9"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"4"	"0"	"33.6"	"26.9"	"23.4"	"28.0"	"32.1"	"21.1"	"49.7"	"0.8"	"241.3"	"243.8"	"426.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14257"	"Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"317"	"36.9"	"4.40"	"1295.02"	"12.80"	"2"	"2"	""	"ER/Golgi;nucleus"	"other molecular function"	"Pf13202"	"5955"	"ENSG00000117906"	"RCN2"	"A8MTG6; F8WCY5; hsa:5955; Q14257; Q53XN8"	""	""	"0"	"0"	"123.7"	"74.4"	"95.6"	"88.1"	"97.3"	"95.0"	"206.2"	"0.9"	"584.6"	"584.5"	"924.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95639"	"Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1"	"0.000"	""	"17"	"3"	"5"	"3"	"269"	"30.2"	"8.31"	"745.56"	"12.78"	"2"	"3"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf00642, Pf15663"	"10898"	"ENSG00000160917"	"CPSF4"	"D6W5S8; hsa:10898; O95639; Q6FGE6; Q86TF8; Q9BTW6"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"mRNA processing"	"8"	"0"	"112.5"	"82.7"	"82.3"	"92.1"	"82.4"	"46.9"	"205.8"	"10.8"	"595.5"	"596.3"	"906.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9A6"	"Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1"	"0.000"	""	"7"	"4"	"7"	"4"	"602"	"68.2"	"6.43"	"977.23"	"12.75"	"3"	"4"	""	""	""	"Pf00560, Pf13855"	"55631"	"ENSG00000066557"	"LRRC40"	"hsa:55631; Q9BTR7; Q9H9A6; Q9NSK1; Q9NXC1"	""	""	"0"	"0"	"28.1"	"25.3"	"42.7"	"29.7"	"28.5"	"28.8"	"41.9"	"3.4"	"1249.1"	"1330.5"	"2761.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2T1"	"GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1"	"0.000"	""	"13"	"4"	"7"	"4"	"348"	"37.9"	"7.23"	"1113.54"	"12.69"	"3"	"4"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"51292"	"ENSG00000100938; ENSG00000284752"	"GMPR2"	"D3DS66; hsa:51292; Q567T0; Q6IAJ8; Q86T14; Q9P2T1"	"Purine salvage"	""	"1"	"0"	"34.7"	"22.2"	"40.0"	"38.1"	"50.3"	"73.9"	"177.2"	"0.0"	"2636.2"	"2599.9"	"4390.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCA5"	"Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"1"	"518"	"55.2"	"8.95"	"1258.54"	"12.65"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"25940"	"ENSG00000119812"	"FAM98A"	"B2RNA2; hsa:25940; Q8NCA5; Q9Y3Y6"	""	""	"0"	"0"	"0.0"	"2.1"	"0.0"	"0.0"	"2.3"	"0.0"	"5.2"	"0.0"	"29.8"	"35.8"	"51.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2D4"	"Exocyst complex component 6B OS=Homo sapiens OX=9606 GN=EXOC6B PE=1 SV=3"	"0.000"	""	"4"	"3"	"6"	"3"	"811"	"94.1"	"6.46"	"1210.26"	"12.64"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other cell component"	""	"Pf04091"	"23233"	"ENSG00000144036"	"EXOC6B"	"B8ZZY3; hsa:23233; Q9Y2D4"	""	"Ciliary landscape"	"1"	"0"	"10.7"	"5.3"	"20.5"	"10.1"	"13.1"	"13.3"	"44.2"	"4.7"	"600.4"	"609.5"	"1096.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWK9"	"Cytoskeleton-associated protein 2 OS=Homo sapiens OX=9606 GN=CKAP2 PE=1 SV=1"	"0.000"	""	"6"	"4"	"5"	"4"	"683"	"76.9"	"9.41"	"310.97"	"12.61"	"1"	"4"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	""	"Pf15297"	"26586"	"ENSG00000136108"	"CKAP2"	"A2BDE0; A5YM58; B4DR35; E9PD90; hsa:26586; Q3KRA5; Q5VXB4; Q8IWV5; Q8IWV6; Q8WWK9; Q96FH9; Q9H012; Q9H0D0; Q9H988; Q9HC49; Q9NVG4"	""	""	"0"	"0"	"194.6"	"185.0"	"222.7"	"193.5"	"185.9"	"199.6"	"597.4"	"0.0"	"2213.2"	"2369.1"	"4029.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NV88"	"Integrator complex subunit 9 OS=Homo sapiens OX=9606 GN=INTS9 PE=1 SV=2"	"0.000"	""	"7"	"3"	"4"	"3"	"658"	"73.8"	"6.33"	"373.00"	"12.60"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	""	"Pf16661"	"55756"	"ENSG00000104299"	"INTS9"	"B7Z560; B7Z6M5; hsa:55756; O00224; Q8TB16; Q9NV88"	"RNA polymerase II transcribes snRNA genes"	"1p36 copy number variation syndrome"	"2"	"0"	"14.4"	"13.4"	"18.3"	"13.4"	"17.4"	"16.2"	"32.7"	"1.5"	"344.3"	"340.3"	"797.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30050"	"60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1"	"0.000"	""	"38"	"5"	"9"	"5"	"165"	"17.8"	"9.42"	"1766.54"	"12.60"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"6136"	"ENSG00000197958"	"RPL12"	"hsa:6136; P30050; Q5VVV2; Q6PB27"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"97.5"	"69.2"	"127.7"	"112.9"	"91.0"	"92.1"	"538.9"	"0.4"	"2272.9"	"2260.0"	"4165.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13555"	"Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens OX=9606 GN=CAMK2G PE=1 SV=4"	"0.000"	""	"10"	"3"	"5"	"2"	"558"	"62.6"	"7.83"	"746.87"	"12.58"	"2"	"3"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf08332"	"818"	"ENSG00000148660"	"CAMK2G"	"A0A0A0MS52; A0A0A0MT11; hsa:818; O00561; O15378; Q13279; Q13282; Q13555; Q13556; Q5SQZ3; Q5SQZ4; Q5SWX4; Q7KYX5; Q8N4I3; Q8NIA4"	"Ion homeostasis; Ion transport by P-type ATPases; Assembly and cell surface presentation of NMDA receptors; Signaling by BRAF and RAF1 fusions; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"Energy metabolism; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Splicing factor NOVA regulated synaptic proteins; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Calcium regulation in cardiac cells; ErbB signaling pathway"	"31"	"0"	"19.6"	"9.5"	"25.4"	"22.6"	"18.4"	"17.8"	"45.6"	"2.0"	"372.0"	"395.7"	"746.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08579"	"U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1"	"0.000"	""	"13"	"4"	"10"	"2"	"225"	"25.5"	"9.72"	"1352.50"	"12.58"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6629"	"ENSG00000125870"	"SNRPB2"	"B2R7J3; D3DW21; hsa:6629; P08579; Q9UJD4"	"mRNA Splicing - Major Pathway"	"mRNA processing; Ciliary landscape"	"3"	"0"	"591.2"	"388.4"	"509.5"	"464.6"	"433.5"	"438.6"	"749.6"	"0.0"	"1774.8"	"1867.7"	"3795.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53680"	"AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2"	"0.000"	""	"27"	"4"	"7"	"4"	"142"	"17.0"	"6.18"	"949.36"	"12.55"	"3"	"4"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01217"	"1175"	"ENSG00000042753"	"AP2S1"	"B2R4Z4; hsa:1175; O75977; P53680; Q6PK67"	"Potential therapeutics for SARS; LDL clearance; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome"	"18"	"0"	"66.8"	"48.6"	"73.7"	"70.6"	"82.3"	"102.3"	"258.0"	"9.8"	"2073.3"	"2008.8"	"3228.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23919"	"Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4"	"0.000"	""	"15"	"4"	"6"	"4"	"212"	"23.8"	"8.27"	"925.69"	"12.53"	"2"	"4"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf02223"	"1841"	"ENSG00000168393"	"DTYMK"	"B7ZW70; hsa:1841; P23919; Q6FGX1; Q9BUX4"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism; 2q37 copy number variation syndrome"	"3"	"0"	"77.1"	"54.4"	"77.4"	"70.4"	"62.8"	"59.7"	"171.6"	"1.1"	"1127.2"	"1146.4"	"2368.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35250"	"Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3"	"0.000"	""	"13"	"3"	"5"	"3"	"354"	"39.1"	"6.44"	"815.52"	"12.52"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5982"	"ENSG00000049541"	"RFC2"	"B5BU07; D3DXG3; hsa:5982; P32846; P35250; Q9BU93"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Homologous Recombination (HRR); HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Activation of ATR in response to replication stress; Termination of translesion DNA synthesis; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"DNA replication; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"27"	"0"	"13.1"	"9.2"	"11.2"	"9.2"	"11.3"	"9.3"	"23.0"	"2.5"	"236.5"	"218.6"	"517.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVM0"	"Coiled-coil domain-containing protein 50 OS=Homo sapiens OX=9606 GN=CCDC50 PE=1 SV=1"	"0.000"	""	"17"	"4"	"7"	"4"	"306"	"35.8"	"6.65"	"2095.65"	"12.50"	"4"	"3"	"other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf15295"	"152137"	"ENSG00000152492"	"CCDC50"	"hsa:152137; Q86VH7; Q8IVM0"	""	""	"0"	"0"	"158.3"	"127.8"	"135.6"	"138.5"	"134.0"	"146.5"	"238.6"	"0.0"	"1312.7"	"1389.6"	"2008.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUQ7"	"Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"2"	"758"	"88.6"	"9.14"	"1192.31"	"12.47"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf09732, Pf10312"	"58509"	"ENSG00000105298"	"CACTIN"	"A6NNA9; A9UL12; hsa:58509; O75229; Q7LE08; Q8WUQ7; Q9BTA6; Q9Y5A4"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"9.8"	"6.9"	"7.6"	"4.0"	"4.9"	"8.8"	"16.5"	"0.0"	"151.9"	"143.7"	"332.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWH5"	"Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1"	"0.000"	""	"11"	"3"	"4"	"3"	"349"	"37.2"	"8.25"	"263.71"	"12.45"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01509"	"142940"	"ENSG00000165832"	"TRUB1"	"B2R716; hsa:142940; Q53ES2; Q8WWH5"	""	""	"0"	"0"	"36.9"	"25.6"	"33.9"	"26.5"	"36.3"	"36.7"	"69.6"	"1.3"	"616.4"	"616.8"	"1514.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43301"	"Heat shock 70 kDa protein 12A OS=Homo sapiens OX=9606 GN=HSPA12A PE=1 SV=2"	""	""	"8"	"3"	"4"	"3"	"675"	"74.9"	"6.77"	""	"12.44"	""	"3"	""	"nucleus;other cell component"	"other molecular function"	""	"259217"	"ENSG00000165868"	"HSPA12A"	"hsa:259217; O43301"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"23.0"	"18.3"	"17.5"	"23.2"	"16.5"	"23.2"	"31.3"	"2.2"	"485.2"	"510.6"	"960.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09622"	"Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2"	"0.000"	""	"6"	"3"	"4"	"3"	"509"	"54.1"	"7.85"	"306.14"	"12.44"	"1"	"3"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02852, Pf07992"	"1738"	"ENSG00000091140"	"DLD"	"B2R5X0; B4DHG0; B4DT69; hsa:1738; P09622; Q14131; Q14167; Q59EV8; Q8WTS4"	"Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Branched-chain amino acid catabolism; Glycine degradation"	"Fatty acid beta-oxidation; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Tryptophan metabolism; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; 10q11.21q11.23 copy number variation syndrome; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"18"	"0"	"115.5"	"92.4"	"82.9"	"80.8"	"85.8"	"102.5"	"196.9"	"4.1"	"1268.1"	"1209.7"	"2526.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61011"	"Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"504"	"55.7"	"8.75"	"823.81"	"12.44"	"2"	"3"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00448, Pf02881, Pf02978"	"6729"	"ENSG00000100883"	"SRP54"	"B2R759; B4DUW6; hsa:6729; P13624; P61011"	"SRP-dependent cotranslational protein targeting to membrane"	"VEGFA-VEGFR2 signaling; mRNA processing"	"3"	"0"	"21.8"	"16.6"	"27.6"	"16.0"	"17.6"	"27.2"	"45.8"	"1.9"	"444.1"	"446.4"	"953.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBX8"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma OS=Homo sapiens OX=9606 GN=PIP4K2C PE=1 SV=3"	"0.000"	""	"11"	"4"	"6"	"4"	"421"	"47.3"	"6.84"	"1022.69"	"12.39"	"2"	"4"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf01504"	"79837"	"ENSG00000166908"	"PIP4K2C"	"B2RDL3; B4DM11; B4DY44; hsa:79837; Q8TBX8; Q9H6N2"	"Synthesis of PIPs at the plasma membrane; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"Regulation of actin cytoskeleton"	"5"	"0"	"15.1"	"15.0"	"33.2"	"25.2"	"30.5"	"26.9"	"78.3"	"2.6"	"766.1"	"716.6"	"1354.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53041"	"Serine/threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1"	"0.000"	""	"9"	"4"	"7"	"4"	"499"	"56.8"	"6.28"	"1431.15"	"12.38"	"4"	"3"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00149, Pf00515, Pf08321"	"5536"	"ENSG00000011485"	"PPP5C"	"hsa:5536; P53041; Q16722; Q53XV2"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Negative regulation of MAPK pathway; ESR-mediated signaling"	"MAPK signaling pathway; ATM signaling in development and disease"	"5"	"0"	"44.0"	"38.7"	"57.2"	"50.6"	"49.7"	"45.1"	"75.1"	"3.9"	"2337.8"	"2379.9"	"4408.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15061"	"WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3"	"0.000"	""	"9"	"4"	"6"	"4"	"677"	"74.8"	"5.57"	"1184.71"	"12.36"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04003"	"23160"	"ENSG00000163811"	"WDR43"	"hsa:23160; Q15061; Q15395; Q92577"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"197.1"	"156.5"	"257.0"	"209.3"	"176.6"	"192.9"	"465.8"	"0.9"	"2540.1"	"2501.2"	"4389.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH03"	"Neuronal-specific septin-3 OS=Homo sapiens OX=9606 GN=SEPTIN3 PE=1 SV=3"	"0.000"	""	"13"	"3"	"5"	"3"	"358"	"40.7"	"7.20"	"667.17"	"12.34"	"2"	"3"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55964"	"ENSG00000100167"	"SEPTIN3"	"B1AHR0; hsa:55964; Q2NKJ7; Q59GF7; Q6IBZ6; Q8N3P3; Q9HD35; Q9UH03"	""	""	"0"	"0"	"4.0"	"3.6"	"5.1"	"5.1"	"8.1"	"6.0"	"10.5"	"1.1"	"165.5"	"158.3"	"275.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07919"	"Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2"	"0.000"	""	"42"	"4"	"6"	"4"	"91"	"10.7"	"4.44"	"1142.87"	"12.31"	"3"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02320"	"7388"	"ENSG00000173660"	"UQCRH"	"B2R4V9; D3DQ18; hsa:7388; P07919; Q5TDF6; Q6LDB8; Q9BQ91"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"360.7"	"234.5"	"307.4"	"285.6"	"267.9"	"214.3"	"346.8"	"0.0"	"1344.3"	"1268.5"	"2557.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99584"	"Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1"	"0.000"	""	"30"	"3"	"6"	"3"	"98"	"11.5"	"6.16"	"1202.17"	"12.31"	"2"	"2"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6284"	"ENSG00000189171"	"S100A13"	"hsa:6284; Q52PI9; Q6FGF8; Q99584"	""	""	"0"	"0"	"11.4"	"11.1"	"17.4"	"16.0"	"18.3"	"12.5"	"32.5"	"12.6"	"1397.3"	"1459.6"	"3750.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43490"	"Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1"	"0.000"	""	"9"	"5"	"9"	"5"	"491"	"55.5"	"7.15"	"1752.19"	"12.30"	"5"	"4"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf04095, Pf18127"	"10135"	"ENSG00000105835"	"NAMPT"	"A4D0Q9; A4D0R0; hsa:10135; P43490; Q3KQV0; Q8WW95"	"NPAS4 regulates expression of target genes; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nicotinamide salvaging"	"Adipogenesis; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Caloric restriction and aging; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"9"	"0"	"207.4"	"172.0"	"188.4"	"175.9"	"162.6"	"191.0"	"319.5"	"8.3"	"2345.4"	"2385.5"	"4198.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16527"	"Cysteine and glycine-rich protein 2 OS=Homo sapiens OX=9606 GN=CSRP2 PE=1 SV=3"	"0.000"	""	"20"	"3"	"6"	"3"	"193"	"20.9"	"8.62"	"1256.02"	"12.29"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"1466"	"ENSG00000175183"	"CSRP2"	"hsa:1466; Q16527; Q93030"	""	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity"	"3"	"0"	"80.2"	"88.3"	"93.2"	"96.2"	"82.6"	"86.0"	"255.2"	"5.5"	"680.5"	"771.8"	"1041.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21796"	"Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2"	"0.000"	""	"16"	"4"	"5"	"4"	"283"	"30.8"	"8.54"	"241.98"	"12.29"	"1"	"4"	"cell-cell signaling;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7416"	"ENSG00000213585"	"VDAC1"	"B3KVK4; D3DQ93; hsa:7416; P21796; Q5FVE7; Q9UIQ5; Q9UPL0"	"Ub-specific processing proteases; Pyruvate metabolism; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy; Mitochondrial calcium ion transport"	"Alzheimer's disease and miRNA effects; Alzheimer's disease; Arsenic metabolism and reactive oxygen species generation; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"10"	"0"	"31.7"	"28.9"	"49.4"	"44.2"	"41.3"	"44.1"	"68.2"	"3.0"	"669.9"	"709.7"	"1689.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3B726"	"DNA-directed RNA polymerase I subunit RPA43 OS=Homo sapiens OX=9606 GN=TWISTNB PE=1 SV=1"	"0.000"	""	"9"	"3"	"7"	"3"	"338"	"37.4"	"6.98"	"955.89"	"12.28"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf17875"	"221830"	"ENSG00000105849"	"POLR1F"	"A0PJ45; B7Z724; hsa:221830; Q3B726"	"NoRC negatively regulates rRNA expression; B-WICH complex positively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"7"	"0"	"15.7"	"11.2"	"19.3"	"20.9"	"17.9"	"19.0"	"37.2"	"4.3"	"1434.8"	"1349.8"	"2584.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38398"	"Breast cancer type 1 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA1 PE=1 SV=2"	"0.000"	""	"2"	"3"	"4"	"3"	"1863"	"207.6"	"5.41"	"604.61"	"12.27"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00097, Pf00533, Pf12820"	"672"	"ENSG00000012048"	"BRCA1"	"E9PFZ0; hsa:672; O15129; P38398; Q1RMC1; Q3LRJ0; Q3LRJ6; Q6IN79; Q7KYU9"	"Neddylation; KEAP1-NFE2L2 pathway; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Metalloprotease DUBs; Processing of DNA double-strand break ends; TP53 Regulates Transcription of DNA Repair Genes; Meiotic synapsis; Resolution of D-loop Structures through Holliday Junction Intermediates; SUMOylation of DNA damage response and repair proteins; Transcriptional Regulation by E2F6; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Nonhomologous End-Joining (NHEJ); Defective DNA double strand break response due to BRCA1 loss of function; Defective DNA double strand break response due to BARD1 loss of function"	"Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Glioblastoma signaling pathways; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; PI3K-Akt signaling pathway; Breast cancer pathway; DNA repair pathways, full network; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; 5q35 copy number variation; DNA damage response"	"40"	"0"	"24.3"	"15.3"	"24.6"	"22.1"	"29.7"	"14.8"	"56.2"	"3.4"	"478.8"	"496.2"	"1063.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW82"	"WD repeat-containing protein 70 OS=Homo sapiens OX=9606 GN=WDR70 PE=1 SV=1"	"0.000"	""	"6"	"3"	"6"	"3"	"654"	"73.2"	"6.33"	"1226.70"	"12.27"	"3"	"3"	""	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"55100"	"ENSG00000082068"	"WDR70"	"hsa:55100; Q9H053; Q9NW82"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"62.7"	"51.4"	"82.1"	"66.1"	"107.5"	"36.3"	"102.9"	"0.0"	"386.8"	"381.4"	"769.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUF8"	"Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"465"	"52.8"	"6.70"	"370.54"	"12.27"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08007, Pf20514"	"84864"	"ENSG00000170854"	"RIOX2"	"D3DN35; hsa:84864; Q6AHW4; Q6SKS0; Q8IU69; Q8IUF6; Q8IUF7; Q8IUF8; Q96C17; Q96KB0"	"HDMs demethylate histones"	""	"1"	"0"	"41.1"	"42.9"	"35.4"	"36.9"	"31.0"	"42.8"	"75.7"	"0.0"	"913.2"	"1183.7"	"1915.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55735"	"Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3"	"0.000"	""	"11"	"3"	"6"	"3"	"322"	"35.5"	"5.48"	"1259.18"	"12.25"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"6396"	"ENSG00000157020"	"SEC13"	"A8MV37; B4DXJ1; hsa:6396; P55735; Q5BJF0; Q9BRM6; Q9BUG7"	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Separation of Sister Chromatids; HCMV Late Events; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Amino acids regulate mTORC1; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPII-mediated vesicle transport; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Postmitotic nuclear pore complex (NPC) reformation"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"40"	"0"	"127.6"	"77.3"	"144.1"	"142.6"	"146.5"	"129.9"	"196.6"	"0.0"	"1289.8"	"1181.5"	"2162.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62899"	"60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1"	"0.000"	""	"25"	"3"	"8"	"3"	"125"	"14.5"	"10.54"	"1244.34"	"12.25"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01198"	"6160"	"ENSG00000071082"	"RPL31"	"B7Z4K2; D3DVJ4; hsa:6160; P12947; P62899; Q53SQ5; Q6IRZ0; Q6LBJ6"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"183.2"	"149.3"	"182.2"	"164.5"	"169.6"	"171.2"	"478.4"	"0.0"	"1785.7"	"1841.1"	"3094.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB78"	"Lysine-specific histone demethylase 1B OS=Homo sapiens OX=9606 GN=KDM1B PE=1 SV=3"	"0.000"	""	"5"	"4"	"7"	"4"	"822"	"92.0"	"7.87"	"976.25"	"12.24"	"3"	"4"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01593, Pf04433, Pf07496"	"221656"	"ENSG00000165097"	"KDM1B"	"A2A2C5; A2A2C6; hsa:221656; Q5TGV3; Q6AI15; Q6ZUU4; Q8N258; Q8NB78; Q96EL7"	"UCH proteinases; HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"	"Vitamin D-sensitive calcium signaling in depression"	"4"	"0"	"9.7"	"4.0"	"12.6"	"12.0"	"5.7"	"11.6"	"44.6"	"6.6"	"799.5"	"726.8"	"1512.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99733"	"Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1"	"0.000"	""	"8"	"4"	"8"	"2"	"375"	"42.8"	"4.69"	"1125.90"	"12.20"	"4"	"4"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4676"	"ENSG00000205531; ENSG00000273562"	"NAP1L4"	"B2R6J4; F5HFY4; hsa:4676; Q99733"	""	""	"0"	"0"	"32.6"	"17.3"	"32.3"	"27.2"	"20.9"	"31.1"	"112.1"	"0.0"	"629.0"	"640.0"	"1134.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GC5"	"39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2"	"0.000"	""	"11"	"2"	"6"	"2"	"212"	"23.9"	"8.98"	"1223.09"	"12.13"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"51642"	"ENSG00000175581"	"MRPL48"	"B4DN34; hsa:51642; Q49AK7; Q4U2Q4; Q96GC5; Q9P091; Q9Y5J0"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"54.6"	"40.8"	"56.1"	"56.7"	"47.0"	"55.1"	"133.4"	"4.0"	"872.6"	"865.6"	"1956.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75179"	"Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3"	"0.000"	""	"2"	"4"	"7"	"2"	"2603"	"274.1"	"6.52"	"1079.85"	"12.10"	"3"	"4"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00013, Pf12796"	"26057"	"ENSG00000132466"	"ANKRD17"	"E7EUV3; G5E964; hsa:26057; O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9"	""	""	"0"	"2"	"37.0"	"25.5"	"48.1"	"37.8"	"41.3"	"52.7"	"105.1"	"13.1"	"646.3"	"606.3"	"1446.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09497"	"Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1"	"0.000"	""	"14"	"3"	"5"	"3"	"229"	"25.2"	"4.64"	"858.43"	"12.09"	"2"	"3"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01086"	"1212"	"ENSG00000175416"	"CLTB"	"hsa:1212; P09497; Q53Y37; Q6FHW1"	"Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions"	"Ebola virus infection in host; Fragile X syndrome; 5q35 copy number variation"	"11"	"0"	"397.7"	"311.2"	"386.0"	"381.3"	"285.6"	"325.7"	"435.9"	"3.5"	"794.9"	"765.9"	"1360.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H910"	"Jupiter microtubule associated homolog 2 OS=Homo sapiens OX=9606 GN=JPT2 PE=1 SV=1"	"0.000"	""	"24"	"3"	"6"	"3"	"190"	"20.1"	"9.26"	"1273.86"	"12.07"	"3"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf17054"	"90861"	"ENSG00000206053"	"JPT2"	"B1AJY2; B4DLH4; hsa:90861; Q6EIC7; Q9H910"	""	""	"0"	"0"	"76.9"	"53.2"	"77.0"	"75.8"	"79.3"	"71.6"	"98.5"	"7.6"	"613.7"	"567.7"	"1009.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6I3"	"Epsin-1 OS=Homo sapiens OX=9606 GN=EPN1 PE=1 SV=2"	"0.000"	""	"7"	"4"	"7"	"4"	"576"	"60.3"	"4.83"	"1081.67"	"12.05"	"3"	"4"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf01417, Pf02809"	"29924"	"ENSG00000063245"	"EPN1"	"hsa:29924; Q86ST3; Q9HA18; Q9Y6I3"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway"	"5"	"0"	"17.4"	"15.5"	"30.1"	"26.0"	"36.0"	"74.3"	"220.8"	"2.2"	"1162.2"	"1085.5"	"1965.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61353"	"60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2"	"0.000"	""	"25"	"5"	"9"	"5"	"136"	"15.8"	"10.56"	"1217.18"	"12.05"	"4"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00467, Pf01777"	"6155"	"ENSG00000131469"	"RPL27"	"hsa:6155; P08526; P61353; Q4G0A9"	"Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"190.3"	"154.6"	"227.2"	"185.8"	"221.0"	"204.2"	"995.3"	"1.2"	"2568.2"	"2494.1"	"4109.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01085"	"Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"2"	"375"	"41.6"	"7.74"	"1174.84"	"12.05"	"3"	"3"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7073"	"ENSG00000151923"	"TIAL1"	"A8K3T0; A8K4L9; hsa:7073; Q01085"	"FGFR2 alternative splicing"	""	"1"	"1"	"143.3"	"108.0"	"139.7"	"146.4"	"143.7"	"110.4"	"208.1"	"2.0"	"558.4"	"541.7"	"970.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6R0"	"eEF1A lysine and N-terminal methyltransferase OS=Homo sapiens OX=9606 GN=EEF1AKNMT PE=1 SV=1"	"0.000"	""	"7"	"4"	"7"	"4"	"699"	"78.7"	"6.73"	"859.59"	"12.03"	"3"	"3"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01564, Pf08241"	"51603"	"ENSG00000010165"	"METTL13"	"A6NFK0; A8K6S5; hsa:51603; O94940; Q53EZ6; Q5TGP9; Q5TGQ0; Q8N2P8; Q8N6R0; Q96J11; Q96SQ0; Q9Y2Z1; Q9Y3M6"	""	""	"0"	"0"	"57.8"	"41.4"	"82.0"	"70.1"	"64.9"	"65.6"	"134.5"	"6.3"	"1327.2"	"1347.8"	"2861.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14561"	"Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3"	"0.000"	""	"13"	"3"	"6"	"3"	"156"	"17.4"	"4.93"	"1176.43"	"12.03"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;nucleus"	"translation activity;other molecular function"	"Pf00550"	"4706"	"ENSG00000004779"	"NDUFAB1"	"B2R4M1; hsa:4706; O14561; Q9UNV1"	"Glyoxylate metabolism and glycine degradation; Mitochondrial Fatty Acid Beta-Oxidation; Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"7"	"0"	"63.3"	"50.8"	"58.1"	"55.9"	"57.6"	"62.4"	"165.7"	"0.0"	"2273.3"	"2427.7"	"3650.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63167"	"Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1"	"0.000"	""	"33"	"2"	"4"	"2"	"89"	"10.4"	"7.40"	"259.18"	"12.01"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01221"	"8655"	"ENSG00000088986"	"DYNLL1"	"hsa:8655; P63167; Q15701"	"Neutrophil degranulation; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; Intraflagellar transport; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BIM and translocation to mitochondria"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"27"	"0"	"203.3"	"196.0"	"246.5"	"202.1"	"295.8"	"179.5"	"422.7"	"1.4"	"1090.7"	"1260.7"	"1787.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60313"	"Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"960"	"111.6"	"7.87"	"918.12"	"12.00"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00350, Pf19434"	"4976"	"ENSG00000198836"	"OPA1"	"D3DNW4; E5KLJ5; E5KLJ6; E5KLJ7; E5KLK1; E5KLK2; hsa:4976; O60313"	"Regulation of Apoptosis"	"Orexin receptor pathway"	"2"	"0"	"8.8"	"6.5"	"14.4"	"8.0"	"15.1"	"11.6"	"27.3"	"5.3"	"453.1"	"470.6"	"953.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27694"	"Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"4"	"3"	"616"	"68.1"	"7.21"	"347.21"	"11.99"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336, Pf04057, Pf08646, Pf16900"	"6117"	"ENSG00000132383"	"RPA1"	"A8K0Y9; hsa:6117; P27694; Q59ES9"	"SUMOylation of DNA damage response and repair proteins; PCNA-Dependent Long Patch Base Excision Repair; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Homologous recombination; Retinoblastoma gene in cancer; ATR signaling; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"39"	"0"	"68.7"	"51.6"	"87.2"	"69.5"	"69.1"	"57.7"	"149.1"	"2.2"	"641.1"	"623.1"	"1404.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14331"	"Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1"	"0.000"	""	"20"	"4"	"7"	"4"	"258"	"29.2"	"9.01"	"1634.33"	"11.95"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf06229"	"2483"	"ENSG00000109536; ENSG00000275145; ENSG00000283153; ENSG00000283630"	"FRG1"	"A8K775; hsa:2483; Q14331"	""	""	"0"	"0"	"40.8"	"30.4"	"49.6"	"43.0"	"50.2"	"45.0"	"76.3"	"1.4"	"1165.0"	"1125.0"	"1767.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14690"	"Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3"	"0.000"	""	"2"	"4"	"8"	"4"	"1871"	"208.6"	"8.87"	"1350.14"	"11.94"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00575, Pf05843"	"22984"	"ENSG00000148843"	"PDCD11"	"hsa:22984; Q14690; Q2TA92; Q5W093; Q6P2J3; Q86VQ8; Q9H4P1"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"93.4"	"88.0"	"98.1"	"94.7"	"76.6"	"94.4"	"218.5"	"1.2"	"999.1"	"985.4"	"2015.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSZ5"	"Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2"	"0.000"	""	"2"	"3"	"5"	"3"	"2229"	"242.8"	"8.34"	"620.28"	"11.93"	"2"	"3"	"other biological processes"	""	""	"Pf07001"	"84726"	"ENSG00000288701"	"PRRC2B"	"hsa:84726; O60270; Q5JSZ5; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683"	""	""	"0"	"0"	"70.0"	"59.1"	"51.7"	"63.5"	"53.8"	"65.3"	"195.6"	"0.9"	"449.1"	"483.8"	"778.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H993"	"Damage-control phosphatase ARMT1 OS=Homo sapiens OX=9606 GN=ARMT1 PE=1 SV=1"	"0.000"	""	"8"	"2"	"5"	"2"	"441"	"51.1"	"5.76"	"745.88"	"11.90"	"2"	"2"	"other metabolic processes;stress response"	""	"other molecular function"	"Pf01937"	"79624"	"ENSG00000146476"	"ARMT1"	"hsa:79624; Q96FC6; Q9H993; Q9UFY5"	""	""	"0"	"0"	"8.5"	"2.4"	"7.6"	"9.7"	"7.6"	"9.1"	"26.3"	"6.8"	"504.1"	"452.4"	"1466.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32322"	"Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2"	"0.000"	""	"13"	"3"	"5"	"2"	"319"	"33.3"	"7.61"	"1047.03"	"11.87"	"2"	"3"	"other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"5831"	"ENSG00000183010"	"PYCR1"	"A6NFM2; B4DMU0; hsa:5831; P32322; Q6FHI4; Q96DI6; Q9HBQ4"	"Glutamate and glutamine metabolism"	"Amino acid metabolism; Metabolic reprogramming in colon cancer"	"3"	"1"	"11.5"	"11.2"	"22.5"	"16.0"	"18.7"	"12.4"	"29.5"	"5.8"	"253.9"	"229.6"	"486.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82664"	"28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2"	"0.000"	""	"16"	"2"	"4"	"2"	"201"	"23.0"	"8.00"	"1186.24"	"11.87"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"55173"	"ENSG00000048544"	"MRPS10"	"B2RE89; hsa:55173; P82664; Q9H3E5; Q9NVR3"	"Mitochondrial translation elongation; Mitochondrial translation initiation; Mitochondrial translation termination"	""	"3"	"0"	"25.5"	"18.2"	"24.4"	"20.3"	"25.2"	"26.8"	"40.7"	"0.0"	"637.1"	"670.8"	"1194.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WU90"	"Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1"	"0.000"	""	"12"	"5"	"8"	"5"	"426"	"48.6"	"5.31"	"1407.89"	"11.86"	"3"	"4"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00642, Pf16543"	"55854"	"ENSG00000065548"	"ZC3H15"	"B4DMW2; D3DPG7; hsa:55854; Q5QTQ4; Q8WU90; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"192.0"	"152.1"	"215.7"	"193.7"	"183.4"	"195.1"	"605.1"	"7.5"	"2791.3"	"2848.2"	"6994.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C36"	"Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"1"	"320"	"33.6"	"7.77"	"1076.53"	"11.85"	"2"	"2"	"other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"29920"	"ENSG00000143811"	"PYCR2"	"A8K798; hsa:29920; Q7Z515; Q96C36; Q9Y5J4"	"Glutamate and glutamine metabolism"	"Metabolic reprogramming in colon cancer"	"2"	"0"	"31.2"	"27.7"	"37.4"	"23.7"	"16.7"	"28.8"	"94.5"	"0.0"	"335.8"	"330.9"	"597.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75534"	"Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2"	"0.000"	""	"6"	"5"	"8"	"5"	"798"	"88.8"	"6.25"	"1270.99"	"11.84"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf00313, Pf12901"	"7812"	"ENSG00000009307"	"CSDE1"	"A8K281; E9PGZ0; G5E9Q2; hsa:7812; O75534; O94961; Q5TF04; Q5TF05; Q68DF1; Q68DI9; Q9Y2S4"	""	""	"0"	"0"	"140.4"	"113.7"	"166.4"	"172.6"	"140.7"	"109.8"	"212.5"	"0.0"	"1458.6"	"1611.3"	"3298.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84098"	"60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1"	"0.000"	""	"17"	"5"	"8"	"4"	"196"	"23.5"	"11.47"	"1915.70"	"11.83"	"5"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01280"	"6143"	"ENSG00000108298"	"RPL19"	"B2R4K2; hsa:6143; P14118; P22908; P84098; Q502Y6; Q7Z6E4"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"184.8"	"138.1"	"229.1"	"189.7"	"184.0"	"193.3"	"470.0"	"7.5"	"1033.7"	"1031.2"	"1782.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND76"	"Cyclin-Y OS=Homo sapiens OX=9606 GN=CCNY PE=1 SV=2"	"0.000"	""	"7"	"2"	"5"	"2"	"341"	"39.3"	"7.20"	"732.10"	"11.82"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134"	"219771"	"ENSG00000108100"	"CCNY"	"B7ZKX9; D3DRY9; hsa:219771; Q2M3V4; Q2TU96; Q6NT86; Q7Z4U7; Q8ND76; Q8TEX2; Q8TEX3; Q96M99; Q96P45"	""	""	"0"	"0"	"40.1"	"26.3"	"62.2"	"47.3"	"46.4"	"50.8"	"91.6"	"1.7"	"1043.0"	"1143.3"	"2221.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q49A26"	"Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4"	"0.000"	""	"6"	"3"	"5"	"3"	"553"	"60.5"	"9.17"	"1072.35"	"11.80"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf03446, Pf14833"	"84656"	"ENSG00000140632"	"GLYR1"	"B4DL47; C9JJ40; C9JJ60; hsa:84656; Q49A26; Q5U632; Q6P1Q2; Q6V3W7; Q9BTI1; Q9BXK2"	""	""	"0"	"0"	"37.4"	"28.1"	"48.1"	"35.5"	"38.1"	"47.8"	"116.9"	"3.1"	"511.5"	"516.8"	"1130.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96D46"	"60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1"	"0.000"	""	"8"	"4"	"6"	"4"	"503"	"57.6"	"7.14"	"728.84"	"11.80"	"2"	"4"	"transport;other biological processes"	"nucleus;other cell component"	"translation activity;other molecular function"	"Pf04981"	"51068"	"ENSG00000169251"	"NMD3"	"D3DNM7; hsa:51068; Q96D46; Q9Y2Z6"	""	""	"0"	"0"	"82.4"	"45.5"	"87.3"	"92.4"	"94.5"	"67.3"	"117.1"	"0.0"	"1090.4"	"1029.8"	"2261.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWM7"	"Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1075"	"113.3"	"8.59"	"1511.68"	"11.79"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"11273"	"ENSG00000168488"	"ATXN2L"	"A8K1R6; B9EGM2; E9PAR9; hsa:11273; O95135; Q63ZY4; Q6NVJ8; Q6PJW6; Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q8WWM7; Q99703"	""	"16p11.2 distal deletion syndrome"	"1"	"0"	"138.7"	"91.3"	"123.6"	"124.7"	"79.3"	"118.0"	"250.5"	"0.7"	"768.7"	"697.1"	"1477.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18859"	"ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1"	"0.000"	""	"36"	"2"	"3"	"2"	"108"	"12.6"	"9.52"	"383.86"	"11.75"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05511"	"522"	"ENSG00000154723"	"ATP5PF"	"hsa:522; J3KQ83; P18859"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"38.9"	"35.4"	"50.5"	"41.9"	"55.9"	"59.4"	"109.2"	"0.4"	"392.8"	"354.7"	"695.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRG9"	"Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"3"	"546"	"59.5"	"7.50"	"1275.02"	"11.75"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"8086"	"ENSG00000094914"	"AAAS"	"hsa:8086; Q5JB47; Q9NRG9; Q9NWI6; Q9UG19"	"HCMV Late Events; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; RHOA GTPase cycle"	""	"29"	"0"	"51.7"	"40.2"	"52.5"	"47.7"	"46.5"	"50.1"	"93.2"	"5.9"	"788.9"	"860.3"	"1535.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQW7"	"Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"6"	"3"	"623"	"69.9"	"5.67"	"1306.71"	"11.69"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf01321, Pf16188, Pf16189"	"7511"	"ENSG00000108039"	"XPNPEP1"	"A8K071; G5E9Y2; G8JLB2; hsa:7511; O15250; Q53EX6; Q8N3Q0; Q96D23; Q9NQW7"	""	""	"0"	"0"	"9.3"	"4.7"	"10.7"	"8.8"	"12.5"	"14.8"	"34.0"	"3.4"	"345.9"	"322.0"	"973.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC35"	"Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3"	"0.000"	""	"4"	"3"	"4"	"3"	"981"	"108.8"	"6.40"	"308.75"	"11.69"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451, Pf07714"	"27436"	"ENSG00000143924"	"EML4"	"A6H8Y6; A6P4T4; A6P4V4; B2RBK3; B2RTW7; B5MCW9; hsa:27436; Q3SWW0; Q53R29; Q53TW8; Q6PJ45; Q9HC35; Q9NV40"	"EML4 and NUDC in mitotic spindle formation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer"	"Non-small cell lung cancer"	"5"	"0"	"49.0"	"41.9"	"53.7"	"58.1"	"51.8"	"62.8"	"86.3"	"1.1"	"919.9"	"950.6"	"1879.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9B1"	"Histone-lysine N-methyltransferase EHMT1 OS=Homo sapiens OX=9606 GN=EHMT1 PE=1 SV=4"	"0.000"	""	"3"	"4"	"7"	"4"	"1298"	"141.4"	"5.76"	"1575.00"	"11.68"	"4"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00856, Pf05033, Pf12796"	"79813"	"ENSG00000181090"	"EHMT1"	"B1AQ58; B1AQ59; hsa:79813; Q86X08; Q8TCN7; Q96F53; Q96JF1; Q96KH4; Q9H9B1"	"PKMTs methylate histone lysines; Senescence-Associated Secretory Phenotype (SASP); Regulation of TP53 Activity through Methylation; Transcriptional Regulation by E2F6; Transcriptional Regulation by VENTX"	"Histone modifications; MTHFR deficiency; Kleefstra syndrome"	"8"	"0"	"125.7"	"90.5"	"110.2"	"107.3"	"103.7"	"111.6"	"219.3"	"0.0"	"766.6"	"760.3"	"1664.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2X3"	"Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1"	"0.000"	""	"8"	"4"	"5"	"4"	"529"	"59.5"	"8.92"	"894.28"	"11.65"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"51602"	"ENSG00000055044"	"NOP58"	"hsa:51602; Q53SA4; Q6PK08; Q9P036; Q9UFN3; Q9Y2X3"	"Major pathway of rRNA processing in the nucleolus and cytosol; SUMOylation of RNA binding proteins; rRNA modification in the nucleus and cytosol"	""	"3"	"0"	"85.0"	"63.2"	"94.3"	"90.1"	"75.4"	"89.0"	"194.6"	"1.3"	"1690.2"	"1726.2"	"3192.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H974"	"Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Homo sapiens OX=9606 GN=QTRT2 PE=1 SV=1"	"0.000"	""	"11"	"3"	"4"	"3"	"415"	"46.7"	"6.81"	"766.50"	"11.64"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01702"	"79691"	"ENSG00000151576"	"QTRT2"	"A6NGE9; B7Z472; B7Z5R2; hsa:79691; J3KR78; Q6IA59; Q9H974"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"36.1"	"27.2"	"31.3"	"26.9"	"27.9"	"26.8"	"66.2"	"1.2"	"554.9"	"554.8"	"1102.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10515"	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3"	"0.000"	""	"6"	"3"	"5"	"3"	"647"	"69.0"	"7.84"	"639.44"	"11.60"	"2"	"3"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1737"	"ENSG00000150768"	"DLAT"	"hsa:1737; P10515; Q16783; Q53EP3"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"8"	"0"	"387.4"	"268.6"	"301.8"	"297.5"	"347.4"	"282.4"	"222.4"	"3.4"	"885.6"	"860.5"	"1741.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60318"	"Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2"	"0.000"	""	"3"	"4"	"6"	"4"	"1980"	"218.3"	"6.39"	"1332.32"	"11.58"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03399, Pf16766, Pf16768, Pf16769"	"8888"	"ENSG00000160294"	"MCM3AP"	"C9JL56; hsa:8888; O60318; Q2M3C1; Q6PJP6; Q9BSY5; Q9UMT4"	""	""	"0"	"0"	"53.7"	"47.5"	"55.5"	"53.3"	"59.6"	"50.5"	"100.1"	"5.7"	"568.2"	"600.0"	"1088.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT52"	"Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1"	"0.000"	""	"3"	"3"	"4"	"3"	"1461"	"155.9"	"7.42"	"383.97"	"11.57"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818"	"23248"	"ENSG00000163125"	"RPRD2"	"A8K6N8; B3KPT1; B4E2Q6; hsa:23248; O75048; Q5VT51; Q5VT52; Q5VT53; Q6MZL4; Q86XD2; Q9P0D7"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	"61.6"	"38.0"	"81.0"	"52.7"	"60.8"	"52.9"	"96.2"	"2.4"	"801.7"	"820.3"	"1899.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPX6"	"Calcium uptake protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=MICU1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"476"	"54.3"	"8.41"	"934.67"	"11.55"	"2"	"3"	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf13202"	"10367"	"ENSG00000107745"	"MICU1"	"A8MV96; B3KN20; B4DJH9; B4DPI1; B5MBY3; D3YTJ3; hsa:10367; O75785; Q9BPX6; Q9H9N6; Q9UFX0"	"Processing of SMDT1"	""	"2"	"0"	"27.0"	"13.5"	"26.1"	"24.9"	"21.2"	"36.4"	"55.4"	"2.4"	"561.8"	"614.0"	"933.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14254"	"Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2"	"0.000"	""	"11"	"3"	"4"	"3"	"428"	"47.0"	"5.25"	"402.86"	"11.54"	"1"	"3"	"cell adhesion;transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	""	"Pf01145"	"2319"	"ENSG00000132589"	"FLOT2"	"hsa:2319; Q14254"	"RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; RND1 GTPase cycle; RND3 GTPase cycle; RHOC GTPase cycle; Synaptic adhesion-like molecules"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"10"	"0"	"11.1"	"5.2"	"16.7"	"12.6"	"14.9"	"16.3"	"18.1"	"0.0"	"455.4"	"461.3"	"1034.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48735"	"Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2"	"0.000"	""	"6"	"3"	"8"	"3"	"452"	"50.9"	"8.69"	"1341.65"	"11.54"	"3"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00180"	"3418"	"ENSG00000182054"	"IDH2"	"B2R6L6; B4DFL2; hsa:3418; P48735; Q96GT3"	"Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle)"	"VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Cerebral organic acidurias, including diseases; TCA cycle (aka Krebs or citric acid cycle)"	"6"	"0"	"132.9"	"133.9"	"132.2"	"116.6"	"121.9"	"144.3"	"213.8"	"1.0"	"1013.3"	"1000.5"	"1535.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63173"	"60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2"	"0.000"	""	"47"	"6"	"10"	"5"	"70"	"8.2"	"10.10"	"1828.62"	"11.53"	"6"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01781"	"6169"	"ENSG00000172809"	"RPL38"	"B2R5A8; hsa:6169; P23411; P63173"	"Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Cytoplasmic ribosomal proteins"	"16"	"1"	"440.6"	"379.8"	"451.7"	"450.7"	"340.9"	"355.8"	"787.1"	"8.1"	"3363.2"	"3447.1"	"6257.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95400"	"CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1"	"0.000"	""	"12"	"4"	"7"	"4"	"341"	"37.6"	"4.61"	"1854.66"	"11.51"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02213"	"10421"	"ENSG00000169217"	"CD2BP2"	"B2RDX2; hsa:10421; O95400; Q9ULP2"	""	"mRNA processing; Ciliary landscape"	"2"	"0"	"93.3"	"69.1"	"92.4"	"91.3"	"87.2"	"93.5"	"183.0"	"0.0"	"1448.0"	"1514.0"	"3732.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06493"	"Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3"	"0.000"	""	"11"	"2"	"4"	"2"	"297"	"34.1"	"8.40"	"1141.36"	"11.49"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"983"	"ENSG00000170312"	"CDK1"	"A8K7C4; C9J497; hsa:983; O60764; P06493"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; Ovarian tumor domain proteases; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; MAPK3 (ERK1) activation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; G1/S-Specific Transcription; Initiation of Nuclear Envelope (NE) Reformation; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Phosphorylation of Emi1"	"miRNA regulation of DNA damage response; Cell cycle; Microtubule cytoskeleton regulation; Spinal cord injury; Retinoblastoma gene in cancer; ATM signaling pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; G1 to S cell cycle control; Cohesin complex - Cornelia de Lange syndrome; Urotensin-II-mediated signaling pathway; DNA damage response"	"49"	"0"	"14.0"	"16.7"	"14.9"	"10.0"	"13.4"	"13.2"	"23.7"	"0.1"	"211.5"	"227.4"	"532.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28066"	"Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3"	"0.000"	""	"13"	"2"	"5"	"2"	"241"	"26.4"	"4.79"	"743.34"	"11.49"	"1"	"2"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5686"	"ENSG00000143106"	"PSMA5"	"B2R8F6; B4E2V4; hsa:5686; P28066; Q3T1C1; Q6IBF7"	"Downstream TCR signaling; UCH proteinases; Separation of Sister Chromatids; ER-Phagosome pathway; FCERI mediated NF-kB activation; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"63"	"0"	"14.0"	"7.7"	"18.6"	"14.1"	"21.4"	"13.9"	"25.7"	"2.8"	"188.3"	"219.5"	"613.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00399"	"Dynactin subunit 6 OS=Homo sapiens OX=9606 GN=DCTN6 PE=1 SV=1"	"0.000"	""	"9"	"1"	"4"	"1"	"190"	"20.7"	"6.32"	"1073.91"	"11.43"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"10671"	"ENSG00000104671"	"DCTN6"	"B2RAC1; hsa:10671; O00399"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	""	"4"	"0"	"22.6"	"15.4"	"28.5"	"23.7"	"22.9"	"27.7"	"48.4"	"0.0"	"668.1"	"660.4"	"1223.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P59998"	"Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3"	"0.000"	""	"23"	"4"	"7"	"4"	"168"	"19.7"	"8.43"	"1087.83"	"11.42"	"3"	"4"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05856"	"10093"	"ENSG00000241553"	"ARPC4"	"C9JWM7; E7ETI0; F6TTL5; hsa:10093; O15509; P59998; Q6P0W5; Q96QJ3"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"Pathogenic Escherichia coli infection"	"6"	"0"	"56.6"	"39.7"	"64.3"	"54.2"	"51.2"	"56.9"	"97.2"	"1.6"	"2342.5"	"2510.2"	"5801.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4V5"	"Hepatoma-derived growth factor-related protein 2 OS=Homo sapiens OX=9606 GN=HDGFL2 PE=1 SV=1"	"0.000"	""	"8"	"3"	"4"	"3"	"671"	"74.3"	"7.49"	"752.08"	"11.39"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00855, Pf11467"	"84717"	"ENSG00000167674"	"HDGFL2"	"hsa:84717; I3L080; K7EQZ6; Q7Z4V5; Q96GI5; Q9BW08"	""	""	"0"	"0"	"26.2"	"19.7"	"27.5"	"26.3"	"21.4"	"30.5"	"39.3"	"1.3"	"350.8"	"328.1"	"681.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01968"	"Inositol polyphosphate 5-phosphatase OCRL OS=Homo sapiens OX=9606 GN=OCRL PE=1 SV=3"	"0.000"	""	"4"	"4"	"7"	"4"	"901"	"104.1"	"6.55"	"1024.27"	"11.39"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00620, Pf03372, Pf16726"	"4952"	"ENSG00000122126"	"OCRL"	"A6NKI1; A8KAP2; B7ZLX2; hsa:4952; O60800; Q01968; Q15684; Q15774; Q4VY09; Q4VY10; Q5JQF1; Q5JQF2; Q9UJG5; Q9UMA5"	"Clathrin-mediated endocytosis; RAC3 GTPase cycle; RHOJ GTPase cycle; Golgi Associated Vesicle Biogenesis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of IP2, IP, and Ins in the cytosol; Synthesis of IP3 and IP4 in the cytosol"	"VEGFA-VEGFR2 signaling; Ciliopathies; Bardet-Biedl syndrome"	"11"	"0"	"63.8"	"55.8"	"76.7"	"68.6"	"75.6"	"73.4"	"106.3"	"0.3"	"904.3"	"938.8"	"1797.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52732"	"Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1056"	"119.1"	"5.64"	"1086.26"	"11.30"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf13931"	"3832"	"ENSG00000138160"	"KIF11"	"A0AV49; B2RMV3; hsa:3832; P52732; Q15716; Q5VWX0"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	""	"3"	"0"	"10.2"	"10.9"	"11.2"	"9.8"	"10.8"	"11.7"	"24.0"	"0.7"	"227.9"	"204.9"	"464.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P52435"	"DNA-directed RNA polymerase II subunit RPB11-a OS=Homo sapiens OX=9606 GN=POLR2J PE=1 SV=1"	""	""	"31"	"2"	"2"	"2"	"117"	"13.3"	"5.86"	""	"11.29"	""	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"5439"	"ENSG00000005075"	"POLR2J"	"A5D6V8; hsa:5439; O43375; P52435"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"20.3"	"16.2"	"16.0"	"19.8"	"17.6"	"21.6"	"40.6"	"1.6"	"343.3"	"347.3"	"911.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6FIF0"	"AN1-type zinc finger protein 6 OS=Homo sapiens OX=9606 GN=ZFAND6 PE=1 SV=2"	"0.000"	""	"21"	"4"	"5"	"4"	"208"	"22.5"	"7.20"	"671.58"	"11.27"	"2"	"3"	"cell organization and biogenesis;transport;other biological processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf01428, Pf01754"	"54469"	"ENSG00000086666"	"ZFAND6"	"D3DW92; D3DW94; hsa:54469; O95792; Q6FIF0; Q9BQF7; Q9GZY3"	"Peroxisomal protein import"	""	"1"	"0"	"64.4"	"41.1"	"72.8"	"58.1"	"68.0"	"63.8"	"109.6"	"0.5"	"1869.4"	"1866.8"	"3496.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13011"	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2"	"0.000"	""	"14"	"4"	"6"	"4"	"328"	"35.8"	"8.00"	"1404.37"	"11.24"	"3"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00378"	"1891"	"ENSG00000104823; ENSG00000282853"	"ECH1"	"A8K745; hsa:1891; Q13011; Q8WVX0; Q96EZ9"	"Peroxisomal protein import"	"Fatty acid biosynthesis; IL-18 signaling pathway"	"3"	"0"	"163.2"	"128.4"	"152.2"	"174.4"	"137.6"	"158.6"	"199.7"	"1.3"	"1182.4"	"1131.5"	"3121.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50914"	"60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4"	"0.000"	""	"24"	"6"	"8"	"6"	"215"	"23.4"	"10.93"	"1160.06"	"11.22"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01929"	"9045"	"ENSG00000188846"	"RPL14"	"hsa:9045; P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8; Q9BW65; Q9BYF6"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"218.8"	"186.6"	"240.2"	"200.2"	"285.9"	"209.6"	"956.0"	"3.4"	"2169.8"	"2170.0"	"3592.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00186"	"Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"592"	"67.7"	"7.80"	"702.79"	"11.18"	"2"	"3"	"cell adhesion;cell-cell signaling;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00995"	"6814"	"ENSG00000116266"	"STXBP3"	"A8K269; A8K5K7; hsa:6814; O00186; Q53FW1; Q86YJ3; Q9UPD7"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Disinhibition of SNARE formation"	"Insulin signaling"	"3"	"0"	"0.0"	"0.0"	"11.4"	"4.0"	"11.6"	"3.2"	"10.6"	"0.0"	"158.2"	"146.4"	"481.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP81"	"Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"518"	"58.2"	"8.13"	"1145.35"	"11.18"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00587"	"54938"	"ENSG00000104835; ENSG00000283104"	"SARS2"	"A6NHW7; B4DE10; hsa:54938; Q9BVP3; Q9NP81"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"20.3"	"12.5"	"22.0"	"15.4"	"16.6"	"18.5"	"32.1"	"4.4"	"352.2"	"399.5"	"1032.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7Z3"	"Nuclear exosome regulator NRDE2 OS=Homo sapiens OX=9606 GN=NRDE2 PE=1 SV=3"	"0.000"	""	"5"	"5"	"7"	"5"	"1164"	"132.6"	"7.68"	"1440.18"	"11.18"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08424"	"55051"	"ENSG00000119720"	"NRDE2"	"B4DH71; hsa:55051; Q4G0A7; Q9H7Z3; Q9NWH6"	""	""	"0"	"0"	"60.4"	"39.4"	"65.1"	"59.7"	"64.9"	"56.9"	"115.6"	"4.4"	"1180.7"	"1263.0"	"2260.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40425"	"Pre-B-cell leukemia transcription factor 2 OS=Homo sapiens OX=9606 GN=PBX2 PE=1 SV=2"	"0.000"	""	"10"	"2"	"3"	"2"	"430"	"45.9"	"7.56"	"472.11"	"11.16"	"1"	"2"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf03792"	"5089"	"ENSG00000204304; ENSG00000206315; ENSG00000224952; ENSG00000225987; ENSG00000232005; ENSG00000236353; ENSG00000237344"	"PBX2"	"A2BFJ2; hsa:5089; P40425"	""	""	"0"	"0"	"44.5"	"27.6"	"61.5"	"104.6"	"52.8"	"87.6"	"85.3"	"0.0"	"252.4"	"215.0"	"386.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09161"	"Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1"	"0.000"	""	"6"	"4"	"6"	"4"	"790"	"91.8"	"6.43"	"1111.92"	"11.14"	"3"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf09088, Pf09090"	"4686"	"ENSG00000136937"	"NCBP1"	"B2R718; hsa:4686; Q09161; Q59G76; Q5T1V0; Q5T7X2"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RNA polymerase II transcribes snRNA genes; Processing of Intronless Pre-mRNAs; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing; 3q29 copy number variation syndrome"	"29"	"0"	"42.1"	"40.3"	"47.7"	"44.0"	"53.9"	"41.7"	"120.4"	"6.2"	"769.9"	"757.6"	"1430.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52298"	"Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1"	"0.000"	""	"19"	"3"	"6"	"3"	"156"	"18.0"	"8.21"	"493.57"	"11.13"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"22916"	"ENSG00000114503"	"NCBP2"	"B2RE91; B4DMK7; E9PAR5; hsa:22916; P52298; Q14924; Q2TS50"	"Regulation of expression of SLITs and ROBOs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; mRNA Splicing - Major Pathway; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Processing of Intronless Pre-mRNAs; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing; 3q29 copy number variation syndrome"	"29"	"0"	"38.6"	"27.3"	"27.9"	"31.0"	"35.5"	"36.5"	"94.6"	"0.7"	"272.6"	"269.4"	"461.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P19793"	"Retinoic acid receptor RXR-alpha OS=Homo sapiens OX=9606 GN=RXRA PE=1 SV=1"	""	""	"7"	"2"	"3"	"2"	"462"	"50.8"	"7.80"	""	"11.11"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00104, Pf00105, Pf11825"	"6256"	"ENSG00000186350"	"RXRA"	"B3KY83; hsa:6256; P19793; Q2NL52; Q2V504"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Transcriptional activation of mitochondrial biogenesis; Cytoprotection by HMOX1; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Endogenous sterols; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Nuclear Receptor transcription pathway; SUMOylation of intracellular receptors; Carnitine metabolism; Activation of gene expression by SREBF (SREBP); NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; Recycling of bile acids and salts; NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose; Transcriptional regulation of granulopoiesis; RORA activates gene expression; NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis; Synthesis of bile acids and bile salts via 27-hydroxycholesterol; NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake ; NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis"	"Vitamin D metabolism; Energy metabolism; Nuclear receptors; Adipogenesis; Liver X receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Vitamin D receptor pathway; PPAR-alpha pathway; Farnesoid X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; Transcription factor regulation in adipogenesis; Angiopoietin-like protein 8 regulatory pathway; PPAR signaling pathway; Prion disease pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Non-small cell lung cancer; Non-genomic actions of 1,25 dihydroxyvitamin D3; Vitamins A and D - action mechanisms; Nonalcoholic fatty liver disease; Vitamin D in inflammatory diseases; Small cell lung cancer; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; Th17 cell differentiation pathway; Kleefstra syndrome; Vitamin A1 and A5/X pathways; Vitamin A and carotenoid metabolism"	"59"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.6"	"0.0"	"47.6"	"46.8"	"160.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14795"	"Protein unc-13 homolog B OS=Homo sapiens OX=9606 GN=UNC13B PE=1 SV=2"	"0.000"	""	"4"	"5"	"8"	"5"	"1591"	"180.6"	"5.99"	"1983.91"	"11.08"	"5"	"3"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00130, Pf00168, Pf06292"	"10497"	"ENSG00000198722"	"UNC13B"	"hsa:10497; O14795; Q2NKJ5; Q5VYM8"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle"	"Synaptic vesicle pathway; 16p11.2 proximal deletion syndrome; Monoamine transport"	"8"	"0"	"31.7"	"14.7"	"23.7"	"33.0"	"29.6"	"31.8"	"108.0"	"4.7"	"903.3"	"788.8"	"1417.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52815"	"39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2"	"0.000"	""	"18"	"3"	"6"	"3"	"198"	"21.3"	"8.87"	"935.35"	"11.07"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00542, Pf16320"	"6182"	"ENSG00000262814"	"MRPL12"	"hsa:6182; P52815; Q969U0; Q9HCA2; Q9UQJ3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"12.1"	"7.3"	"16.5"	"15.6"	"10.6"	"9.4"	"57.7"	"0.9"	"446.0"	"402.1"	"825.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6GYQ0"	"Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=RALGAPA1 PE=1 SV=1"	"0.000"	""	"2"	"3"	"5"	"3"	"2036"	"229.7"	"6.19"	"807.73"	"11.07"	"2"	"3"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02145, Pf20412"	"253959"	"ENSG00000174373"	"RALGAPA1"	"A6NMA4; B9EK38; C5NU19; hsa:253959; O94960; Q6GYP9; Q6GYQ0; Q6ZT23; Q86YF3; Q86YF5; Q8ND69"	"RHOH GTPase cycle"	""	"1"	"0"	"53.6"	"31.0"	"73.1"	"53.1"	"64.8"	"55.8"	"100.2"	"3.1"	"707.1"	"746.9"	"1357.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94903"	"Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP PE=1 SV=1"	"0.000"	""	"15"	"3"	"6"	"3"	"275"	"30.3"	"7.50"	"1125.64"	"11.06"	"3"	"3"	""	"cytosol;other cell component"	"other molecular function"	"Pf01168"	"11212"	"ENSG00000147471"	"PLPBP"	"hsa:11212; O94903; Q6FI94"	""	""	"0"	"0"	"31.6"	"17.5"	"33.7"	"37.2"	"31.0"	"28.5"	"52.3"	"2.1"	"455.8"	"472.5"	"866.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00178"	"GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3"	"0.000"	""	"6"	"3"	"4"	"3"	"669"	"72.4"	"8.34"	"263.01"	"11.06"	"1"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"9567"	"ENSG00000100226"	"GTPBP1"	"hsa:9567; O00178; Q6IC67"	""	""	"0"	"0"	"10.5"	"7.6"	"16.5"	"13.6"	"13.5"	"12.8"	"36.6"	"4.4"	"296.0"	"302.8"	"774.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMY4"	"Sorting nexin-12 OS=Homo sapiens OX=9606 GN=SNX12 PE=1 SV=4"	"0.000"	""	"33"	"2"	"3"	"2"	"162"	"18.9"	"8.44"	"486.81"	"11.06"	"1"	"2"	"transport;other biological processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf00787"	"29934"	"ENSG00000147164"	"SNX12"	"F8W8K5; hsa:29934; Q8WUG9; Q9UMY4"	""	""	"0"	"0"	"2.3"	"0.0"	"0.0"	"3.4"	"0.0"	"0.0"	"5.3"	"0.5"	"75.1"	"88.7"	"311.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00257"	"E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3"	"0.000"	""	"5"	"2"	"6"	"2"	"560"	"61.3"	"9.36"	"1167.00"	"11.05"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"8535"	"ENSG00000141582"	"CBX4"	"B1PJR7; hsa:8535; O00257; Q6TPI8; Q96C04"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	""	"8"	"0"	"24.2"	"20.6"	"29.1"	"22.5"	"20.4"	"37.8"	"90.0"	"0.0"	"388.8"	"411.8"	"747.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51970"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3"	"0.000"	""	"34"	"5"	"8"	"5"	"172"	"20.1"	"7.65"	"1459.10"	"11.04"	"4"	"4"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06747"	"4702"	"ENSG00000119421"	"NDUFA8"	"B1AM93; hsa:4702; P51970; Q9Y6N0"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"150.9"	"153.4"	"122.7"	"133.9"	"120.4"	"131.6"	"300.5"	"1.9"	"2429.3"	"2468.1"	"5253.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13667"	"Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2"	"0.000"	""	"8"	"4"	"6"	"4"	"645"	"72.9"	"5.07"	"1054.32"	"11.03"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"9601"	"ENSG00000155660"	"PDIA4"	"A8K4K6; hsa:9601; P13667; Q549T6"	""	""	"0"	"0"	"608.8"	"444.3"	"542.7"	"498.1"	"492.5"	"502.8"	"855.2"	"0.0"	"1442.7"	"1481.3"	"2228.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULU4"	"Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8 PE=1 SV=2"	"0.000"	""	"3"	"3"	"4"	"3"	"1186"	"131.6"	"7.20"	"302.30"	"11.01"	"1"	"3"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf12064"	"23613"	"ENSG00000101040"	"ZMYND8"	"B3KVL2; B7Z2A8; B7Z3E0; B7Z680; B7ZM62; E1P5U5; F5H0X3; H7C0U2; hsa:23613; J3KPU3; Q13517; Q2HXV1; Q2HXV2; Q2HXV3; Q2HXV4; Q2HXV7; Q2HXV8; Q2HXV9; Q2HXW0; Q2HXW1; Q2HXW2; Q4JJ94; Q4JJ95; Q5TH09; Q5TH11; Q6MZM1; Q8WXC5; Q9H1F3; Q9H1F4; Q9H1F5; Q9H1L8; Q9H1L9; Q9H2G5; Q9NYN3; Q9UIX6; Q9ULU4"	""	""	"0"	"0"	"52.0"	"34.7"	"63.1"	"49.7"	"57.6"	"42.2"	"102.3"	"0.0"	"984.6"	"1006.2"	"2391.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L5N1"	"COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"327"	"36.1"	"5.73"	"642.74"	"11.01"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01398, Pf13012"	"10980"	"ENSG00000168090"	"COPS6"	"A4D2A3; hsa:10980; O15387; Q7L5N1"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER"	"Nucleotide-binding oligomerization domain (NOD) pathway; Ciliary landscape"	"6"	"0"	"23.7"	"15.0"	"32.8"	"24.5"	"26.9"	"25.4"	"53.6"	"2.3"	"474.1"	"526.1"	"1533.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ52"	"Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2"	"0.000"	""	"4"	"3"	"4"	"3"	"826"	"92.2"	"7.90"	"621.46"	"10.98"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12706, Pf13691"	"60528"	"ENSG00000006744"	"ELAC2"	"B4DPL9; hsa:60528; Q6IA94; Q9BQ52; Q9HAS8; Q9HAS9; Q9NVT1"	"tRNA processing in the nucleus; tRNA processing in the mitochondrion; rRNA processing in the mitochondrion; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	""	"4"	"0"	"6.5"	"5.5"	"11.3"	"7.4"	"11.6"	"7.9"	"21.6"	"1.5"	"317.4"	"351.8"	"886.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15514"	"DNA-directed RNA polymerase II subunit RPB4 OS=Homo sapiens OX=9606 GN=POLR2D PE=1 SV=1"	"0.000"	""	"27"	"3"	"5"	"3"	"142"	"16.3"	"4.79"	"764.83"	"10.98"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf03874"	"5433"	"ENSG00000144231"	"POLR2D"	"hsa:5433; O15514; Q52LT4"	"Transcriptional regulation by small RNAs; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism"	"42"	"0"	"196.7"	"127.8"	"185.1"	"165.2"	"187.9"	"157.7"	"275.7"	"0.3"	"718.3"	"635.3"	"1136.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96LB3"	"Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1"	"0.000"	""	"9"	"3"	"6"	"3"	"600"	"69.2"	"6.00"	"571.01"	"10.97"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"80173"	"ENSG00000096872"	"IFT74"	"hsa:80173; Q3B789; Q5VY34; Q6PGQ8; Q96LB3; Q9H643; Q9H8G7"	"Intraflagellar transport"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Alstrom syndrome; Bardet-Biedl syndrome"	"5"	"0"	"165.0"	"57.9"	"173.5"	"88.5"	"130.1"	"159.2"	"205.1"	"3.2"	"940.8"	"695.1"	"1998.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92547"	"DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3"	"0.000"	""	"3"	"3"	"4"	"3"	"1522"	"170.6"	"6.96"	"590.24"	"10.97"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00533"	"11073"	"ENSG00000163781"	"TOPBP1"	"B7Z7W8; hsa:11073; Q7LGC1; Q92547; Q9UEB9"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51"	"ATR signaling"	"7"	"0"	"22.1"	"19.7"	"30.2"	"19.7"	"31.9"	"27.2"	"34.9"	"1.0"	"681.5"	"636.5"	"1779.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NS86"	"LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1"	"0.000"	""	"9"	"3"	"6"	"3"	"450"	"50.8"	"7.43"	"1004.75"	"10.97"	"3"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf05147"	"55915"	"ENSG00000132434"	"LANCL2"	"B2R8D4; hsa:55915; Q6NSL4; Q8TCQ3; Q9BSR1; Q9NS86"	""	""	"0"	"0"	"18.0"	"10.2"	"31.5"	"19.1"	"21.7"	"19.3"	"47.8"	"4.5"	"534.2"	"485.0"	"1138.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99661"	"Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"2"	"725"	"81.3"	"7.83"	"536.92"	"10.95"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"11004"	"ENSG00000142945"	"KIF2C"	"B3ITR9; hsa:11004; Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q99661; Q9BWV8"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"Microtubule cytoskeleton regulation"	"10"	"0"	"16.0"	"12.3"	"16.7"	"17.9"	"22.6"	"16.8"	"43.8"	"3.1"	"395.0"	"379.5"	"685.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6D9"	"Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"718"	"83.0"	"5.92"	"519.59"	"10.92"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05557"	"8379"	"ENSG00000002822"	"MAD1L1"	"B3KR41; hsa:8379; Q13312; Q75MI0; Q86UM4; Q9UNH0; Q9Y6D9"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; Pleural mesothelioma; CCL18 signaling pathway"	"10"	"0"	"13.1"	"12.4"	"16.8"	"20.4"	"13.2"	"21.1"	"37.5"	"3.0"	"177.1"	"206.5"	"368.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78356"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 beta OS=Homo sapiens OX=9606 GN=PIP4K2B PE=1 SV=1"	"0.000"	""	"11"	"3"	"4"	"1"	"416"	"47.3"	"7.33"	"445.13"	"10.91"	"1"	"3"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf01504"	"8396"	"ENSG00000276293; ENSG00000277292"	"PIP4K2B"	"hsa:8396; P78356; Q5U0E8; Q8TBP2"	"Synthesis of PIPs at the plasma membrane; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"Regulation of actin cytoskeleton; 17q12 copy number variation syndrome"	"6"	"0"	"12.4"	"4.3"	"22.4"	"12.8"	"18.3"	"15.9"	"28.3"	"0.0"	"216.5"	"257.5"	"625.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27448"	"MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5"	"0.000"	""	"4"	"3"	"5"	"2"	"753"	"84.4"	"9.57"	"839.46"	"10.91"	"2"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00627, Pf02149"	"4140"	"ENSG00000075413"	"MARK3"	"A0A0A0MQR8; A0A0A0MST9; A0A0A0MT23; hsa:4140; O60219; P27448; Q86TT8; Q8TB41; Q8WX83; Q96RG1; Q9UMY9; Q9UN34"	"Signaling by BRAF and RAF1 fusions; RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants"	"Complement system in neuronal development and plasticity"	"10"	"1"	"13.3"	"12.7"	"18.1"	"12.4"	"8.0"	"17.7"	"48.9"	"6.8"	"403.5"	"382.6"	"807.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK61"	"Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3"	"0.000"	""	"2"	"3"	"6"	"3"	"1670"	"188.9"	"5.80"	"1063.10"	"10.87"	"3"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12509"	"23272"	"ENSG00000163946"	"TASOR"	"A1L3A4; B5ME28; hsa:23272; Q9H2F7; Q9UK61; Q9UPP7"	""	""	"0"	"0"	"51.5"	"41.3"	"62.0"	"40.5"	"51.5"	"37.4"	"126.4"	"0.0"	"859.6"	"1058.9"	"1824.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YM7"	"Homer protein homolog 1 OS=Homo sapiens OX=9606 GN=HOMER1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"6"	"2"	"354"	"40.3"	"5.44"	"1070.34"	"10.87"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00568"	"9456"	"ENSG00000152413"	"HOMER1"	"B2R688; hsa:9456; O96003; Q86YM5; Q86YM7"	"Neurexins and neuroligins"	"BDNF-TrkB signaling; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; Orexin receptor pathway"	"6"	"0"	"20.8"	"15.8"	"26.9"	"16.7"	"25.2"	"20.1"	"70.8"	"2.1"	"601.9"	"600.5"	"1099.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09496"	"Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1"	"0.000"	""	"15"	"5"	"9"	"5"	"248"	"27.1"	"4.51"	"1347.09"	"10.87"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01086"	"1211"	"ENSG00000122705"	"CLTA"	"A8K4W3; B4DIN1; F5H6N3; hsa:1211; P09496; Q2XPN5; Q53XZ1"	"Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Recycling pathway of L1; MHC class II antigen presentation; Lysosome Vesicle Biogenesis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"Synaptic vesicle pathway; Ebola virus infection in host; Fragile X syndrome"	"17"	"0"	"623.5"	"421.2"	"492.0"	"511.0"	"456.6"	"423.9"	"629.2"	"1.6"	"1403.8"	"1326.2"	"2193.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29372"	"DNA-3-methyladenine glycosylase OS=Homo sapiens OX=9606 GN=MPG PE=1 SV=3"	"0.000"	""	"18"	"3"	"5"	"3"	"298"	"32.8"	"9.57"	"631.66"	"10.79"	"2"	"3"	"DNA metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02245"	"4350"	"ENSG00000103152"	"MPG"	"G5E9E2; hsa:4350; P29372; Q13770; Q15275; Q15961; Q5J9I4; Q96BZ6; Q96S33; Q9NNX5"	"Recognition and association of DNA glycosylase with site containing an affected purine; Cleavage of the damaged purine; Displacement of DNA glycosylase by APEX1"	"Base excision repair; DNA repair pathways, full network"	"5"	"0"	"23.6"	"18.0"	"27.4"	"20.6"	"20.7"	"27.9"	"59.2"	"1.9"	"460.4"	"515.0"	"1041.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50613"	"Cyclin-dependent kinase 7 OS=Homo sapiens OX=9606 GN=CDK7 PE=1 SV=1"	"0.000"	""	"12"	"3"	"5"	"3"	"346"	"39.0"	"8.47"	"934.34"	"10.79"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1022"	"ENSG00000134058; ENSG00000277273"	"CDK7"	"hsa:1022; P50613; Q9BS60; Q9UE19"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"MicroRNAs in cardiomyocyte hypertrophy; Cell cycle; Cardiac hypertrophic response; Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"43"	"0"	"48.5"	"34.7"	"44.8"	"47.8"	"40.8"	"51.0"	"97.1"	"0.0"	"668.6"	"640.1"	"1193.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P2I0"	"Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2"	""	""	"6"	"2"	"2"	"2"	"782"	"88.4"	"5.11"	""	"10.79"	""	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07521, Pf10996, Pf13299, Pf16661"	"53981"	"ENSG00000165934"	"CPSF2"	"B3KME1; hsa:53981; Q6NSJ1; Q9H3W7; Q9P2I0"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"6"	"0"	"11.5"	"7.1"	"8.2"	"10.5"	"11.0"	"5.1"	"21.0"	"0.0"	"103.7"	"97.8"	"194.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27797"	"Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"417"	"48.1"	"4.44"	"588.41"	"10.79"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00262"	"811"	"ENSG00000179218"	"CALR"	"hsa:811; P27797; Q6IAT4; Q9UDG2"	"Scavenging by Class A Receptors; Scavenging by Class F Receptors; ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Assembly of Viral Components at the Budding Site; ATF6 (ATF6-alpha) activates chaperone genes; Calnexin/calreticulin cycle"	"Androgen receptor signaling pathway; Complement system; Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; GDNF signaling; Calcium regulation in cardiac cells"	"13"	"0"	"209.4"	"143.1"	"176.7"	"180.1"	"194.0"	"189.6"	"242.4"	"2.0"	"907.3"	"888.7"	"1292.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q1L5Z9"	"LON peptidase N-terminal domain and RING finger protein 2 OS=Homo sapiens OX=9606 GN=LONRF2 PE=2 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"754"	"83.6"	"5.90"	"923.63"	"10.79"	"2"	"3"	""	"other cell component"	"other molecular function"	"Pf02190, Pf13923"	"164832"	"ENSG00000170500"	"LONRF2"	"B9A006; hsa:164832; Q1L5Z9; Q6ZSR4"	""	""	"0"	"0"	"7.6"	"4.0"	"10.2"	"6.0"	"14.0"	"8.8"	"16.3"	"5.3"	"317.5"	"307.4"	"696.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95163"	"Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3"	"0.000"	""	"3"	"3"	"4"	"3"	"1332"	"150.2"	"5.94"	"436.41"	"10.78"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04762"	"8518"	"ENSG00000070061"	"ELP1"	"hsa:8518; O95163; Q5JSV2; Q9H327; Q9UG87"	"HATs acetylate histones"	""	"1"	"0"	"34.0"	"15.1"	"38.6"	"32.0"	"30.1"	"26.6"	"41.8"	"1.0"	"338.9"	"375.9"	"870.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14247"	"Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"550"	"61.5"	"5.40"	"827.81"	"10.78"	"2"	"3"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf02218, Pf14604"	"2017"	"ENSG00000085733; ENSG00000288401"	"CTTN"	"hsa:2017; Q14247; Q8N707; Q96H99"	"Clathrin-mediated endocytosis; RHO GTPases activate PAKs"	"Pathogenic Escherichia coli infection; Hepatitis C and hepatocellular carcinoma"	"4"	"0"	"76.0"	"67.5"	"76.4"	"74.0"	"73.4"	"75.7"	"136.2"	"0.0"	"1240.2"	"1295.4"	"2798.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92688"	"Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1"	"0.000"	""	"19"	"5"	"8"	"4"	"251"	"28.8"	"4.06"	"1713.48"	"10.77"	"5"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12799"	"10541"	"ENSG00000136938"	"ANP32B"	"B2R9C7; hsa:10541; O00655; P78458; P78459; Q92688"	""	""	"0"	"0"	"186.3"	"178.6"	"241.8"	"192.5"	"227.1"	"193.0"	"576.7"	"7.0"	"2434.1"	"2376.1"	"4188.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULH0"	"Kinase D-interacting substrate of 220 kDa OS=Homo sapiens OX=9606 GN=KIDINS220 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1771"	"196.4"	"6.62"	"380.36"	"10.74"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07693, Pf12796"	"57498"	"ENSG00000134313"	"KIDINS220"	"A1L4N4; hsa:57498; Q4VC08; Q6MZU2; Q9H889; Q9H9E4; Q9NT37; Q9UF42; Q9ULH0"	"RND2 GTPase cycle; RND1 GTPase cycle; ARMS-mediated activation"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Neural crest cell migration in cancer"	"5"	"0"	"32.6"	"15.0"	"59.2"	"52.1"	"44.7"	"27.8"	"48.9"	"3.0"	"376.8"	"318.7"	"697.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXQ5"	"Kelch-like protein 7 OS=Homo sapiens OX=9606 GN=KLHL7 PE=1 SV=2"	"0.000"	""	"8"	"3"	"4"	"3"	"586"	"65.9"	"6.48"	"272.98"	"10.74"	"1"	"3"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00651, Pf01344, Pf07707"	"55975"	"ENSG00000122550"	"KLHL7"	"A4D144; B7Z5I9; G5E9G3; hsa:55975; Q7Z765; Q8IXQ5; Q96MV2; Q9BQF8; Q9UDQ9"	""	""	"0"	"0"	"28.8"	"23.6"	"46.0"	"32.0"	"38.5"	"32.5"	"79.6"	"1.3"	"1168.7"	"1155.4"	"2423.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4Q2"	"HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2"	"0.000"	""	"3"	"2"	"6"	"2"	"680"	"74.5"	"5.11"	"742.17"	"10.72"	"1"	"2"	"transport;other biological processes"	""	"other molecular function"	"Pf13513"	"55027"	"ENSG00000155393"	"HEATR3"	"A8K1N4; hsa:55027; Q7Z4Q2; Q8N525; Q8WV56; Q96CC9; Q9NWN7"	""	""	"0"	"0"	"0.0"	"0.0"	"2.6"	"0.0"	"2.2"	"4.4"	"3.8"	"1.2"	"77.8"	"83.9"	"216.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60343"	"TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2"	"0.000"	""	"3"	"4"	"6"	"4"	"1298"	"146.5"	"7.01"	"694.12"	"10.72"	"2"	"4"	"transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00566, Pf00640, Pf11830"	"9882"	"ENSG00000136111"	"TBC1D4"	"A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; hsa:9882; O60343; Q5W0B9; Q68D14"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"Ciliary landscape; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling"	"4"	"0"	"38.2"	"26.5"	"51.6"	"40.6"	"40.3"	"39.9"	"79.5"	"1.8"	"500.6"	"512.4"	"1095.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ83"	"2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"578"	"63.7"	"7.36"	"541.77"	"10.72"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"26061"	"ENSG00000131373"	"HACL1"	"B4DWI1; B4DXI5; E9PEN4; hsa:26061; Q9BV42; Q9P0A2; Q9UJ83"	"Peroxisomal protein import; Alpha-oxidation of phytanate"	""	"2"	"0"	"22.0"	"14.1"	"23.8"	"19.8"	"26.8"	"25.8"	"47.3"	"0.0"	"573.4"	"488.2"	"923.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28288"	"ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1"	"0.000"	""	"6"	"4"	"7"	"3"	"659"	"75.4"	"9.36"	"964.21"	"10.71"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf06472"	"5825"	"ENSG00000117528"	"ABCD3"	"D3DT46; hsa:5825; P28288; Q15271; Q6NUN5; Q96DA3; Q9H529"	"RHOC GTPase cycle; RHOA GTPase cycle; Class I peroxisomal membrane protein import; ABC transporters in lipid homeostasis"	"Nuclear receptors in lipid metabolism and toxicity; Fragile X syndrome"	"6"	"1"	"107.8"	"71.2"	"132.7"	"99.9"	"105.7"	"96.2"	"203.2"	"0.0"	"1364.8"	"1479.2"	"2700.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW13"	"RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"759"	"85.7"	"9.22"	"734.19"	"10.68"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"55131"	"ENSG00000106344"	"RBM28"	"A4D100; B4DU52; E9PDD9; hsa:55131; Q53H65; Q96CV3; Q9NW13"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"34.0"	"26.8"	"50.8"	"34.2"	"38.5"	"33.0"	"126.9"	"0.0"	"451.4"	"460.1"	"879.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH5"	"Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1"	"0.000"	""	"14"	"4"	"7"	"4"	"326"	"34.8"	"9.09"	"1522.08"	"10.66"	"4"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05172"	"129401"	"ENSG00000163002"	"NUP35"	"B4DP57; B4DYB4; hsa:129401; Q4ZFZ9; Q53S95; Q8NFH5; Q8TDJ1"	"HCMV Late Events; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"202.9"	"181.2"	"191.2"	"194.6"	"162.0"	"202.1"	"561.5"	"0.0"	"1889.1"	"1835.9"	"3445.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20585"	"DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4"	"0.000"	""	"3"	"4"	"7"	"4"	"1137"	"127.3"	"8.02"	"1682.35"	"10.65"	"4"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05192"	"4437"	"ENSG00000113318"	"MSH3"	"A1L480; A1L482; A6NMM6; hsa:4437; P20585; Q6PJT5; Q86UQ6; Q92867"	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2"	"Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network"	"5"	"0"	"64.1"	"45.7"	"70.3"	"57.5"	"52.5"	"62.5"	"131.6"	"3.7"	"488.8"	"482.5"	"874.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N3E9"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3 OS=Homo sapiens OX=9606 GN=PLCD3 PE=1 SV=3"	""	""	"5"	"2"	"2"	"2"	"789"	"89.2"	"6.98"	""	"10.62"	""	"2"	"other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf14788"	"113026"	"ENSG00000161714"	"PLCD3"	"hsa:113026; Q8N3E9; Q8TEC1; Q8TF37; Q96FL6"	"Synthesis of IP3 and IP4 in the cytosol"	"GPR40 pathway; Resistin as a regulator of inflammation"	"3"	"0"	"22.0"	"12.4"	"29.2"	"24.2"	"17.1"	"14.8"	"42.1"	"1.6"	"511.7"	"490.9"	"974.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CP2"	"FLYWCH family member 2 OS=Homo sapiens OX=9606 GN=FLYWCH2 PE=1 SV=1"	"0.000"	""	"26"	"3"	"6"	"3"	"140"	"14.6"	"8.46"	"1116.50"	"10.61"	"3"	"3"	""	""	""	"Pf15423"	"114984"	"ENSG00000162076"	"FLYWCH2"	"hsa:114984; Q96CP2"	""	""	"0"	"0"	"51.0"	"41.5"	"50.9"	"49.5"	"51.6"	"47.5"	"92.9"	"2.3"	"774.2"	"804.4"	"1449.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAU0"	"Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens OX=9606 GN=PLEKHA5 PE=1 SV=1"	"0.000"	""	"3"	"3"	"7"	"2"	"1116"	"127.4"	"7.53"	"1314.42"	"10.60"	"3"	"2"	"developmental processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169, Pf00397"	"54477"	"ENSG00000052126"	"PLEKHA5"	"A0JP03; B4DGS1; E9PHQ3; F5H0I0; hsa:54477; Q6NSF8; Q86ST7; Q8N3K6; Q96DY9; Q9BVR4; Q9C0H7; Q9H924; Q9HAU0; Q9NVK8"	"Synthesis of PIPs at the plasma membrane"	""	"1"	"0"	"48.9"	"37.2"	"42.8"	"46.4"	"45.1"	"38.4"	"92.3"	"0.5"	"420.0"	"408.8"	"750.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14818"	"Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1"	""	""	"12"	"3"	"3"	"3"	"248"	"27.9"	"8.46"	""	"10.59"	""	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5688"	"ENSG00000101182"	"PSMA7"	"B2R515; hsa:5688; O14818; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"99.2"	"77.5"	"99.0"	"105.7"	"108.8"	"110.2"	"180.5"	"0.0"	"1060.9"	"1148.3"	"2312.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3SY69"	"Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L2 PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"923"	"101.7"	"6.52"	"996.13"	"10.56"	"3"	"3"	"other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf00171, Pf00550, Pf00551, Pf02911"	"160428"	"ENSG00000136010"	"ALDH1L2"	"hsa:160428; Q3SY68; Q3SY69; Q68D62; Q6AI55; Q8N922"	"Metabolism of folate and pterines"	""	"1"	"0"	"43.1"	"38.1"	"62.8"	"53.8"	"55.4"	"54.7"	"82.0"	"1.8"	"614.0"	"634.1"	"1239.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXE8"	"Pre-mRNA-splicing factor CWC25 homolog OS=Homo sapiens OX=9606 GN=CWC25 PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"3"	"425"	"49.6"	"10.18"	"795.70"	"10.55"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10197, Pf12542"	"54883"	"ENSG00000273559; ENSG00000276761"	"CWC25"	"A0JLM3; hsa:54883; Q68DK5; Q9NXE8"	"mRNA Splicing - Major Pathway"	"17q12 copy number variation syndrome"	"2"	"0"	"112.9"	"94.3"	"90.3"	"98.9"	"103.4"	"101.2"	"211.6"	"3.2"	"1247.1"	"1256.0"	"2076.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UY6"	"N-alpha-acetyltransferase 40 OS=Homo sapiens OX=9606 GN=NAA40 PE=1 SV=1"	"0.000"	""	"8"	"1"	"4"	"1"	"237"	"27.2"	"7.39"	"964.38"	"10.51"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf00583"	"79829"	"ENSG00000110583"	"NAA40"	"B4DR03; B4DU10; hsa:79829; Q5HYL5; Q86UY6; Q9H897"	""	"Metapathway biotransformation Phase I and II"	"1"	"0"	"12.2"	"3.4"	"17.4"	"16.3"	"14.2"	"9.1"	"19.3"	"1.7"	"278.8"	"289.1"	"563.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12872"	"Splicing factor, suppressor of white-apricot homolog OS=Homo sapiens OX=9606 GN=SFSWAP PE=1 SV=3"	"0.000"	""	"5"	"4"	"6"	"4"	"951"	"104.8"	"8.05"	"950.09"	"10.50"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01805, Pf09750"	"6433"	"ENSG00000061936"	"SFSWAP"	"B2RN45; B7ZM97; F5H6B8; hsa:6433; Q12872; Q6PJF7"	""	"mRNA processing"	"1"	"0"	"81.4"	"64.9"	"82.6"	"70.1"	"72.2"	"67.7"	"177.2"	"8.8"	"845.6"	"857.3"	"1603.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20248"	"Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"432"	"48.5"	"6.54"	"1048.10"	"10.49"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984, Pf16500"	"890"	"ENSG00000145386"	"CCNA2"	"A8K7B6; hsa:890; P20248; Q2M3U6; Q4W5P4; Q6LER8"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; G2 Phase; Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; p53-Dependent G1 DNA Damage Response; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes"	"AMP-activated protein kinase signaling; Cell cycle; Retinoblastoma gene in cancer; IL-18 signaling pathway"	"24"	"0"	"70.7"	"51.6"	"65.5"	"65.7"	"61.1"	"63.6"	"87.3"	"0.0"	"753.4"	"776.1"	"1440.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16220"	"Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=2"	"0.000"	""	"10"	"3"	"4"	"3"	"341"	"36.7"	"5.57"	"756.85"	"10.46"	"1"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170, Pf02173"	"100351999; 100477711; 100586647; 100675162; 100974672; 101010524; 101356881; 101383024; 101608568; 101964691; 102141699; 102246867; 102428529; 102531048; 102748542; 103217717; 103744440; 104680220; 105468005; 105517357; 105549382; 105580103; 105864304; 106967098; 108540349; 109691946; 1385; 459901; 607922; 708717"	"ENSAMEG00000015152; ENSCAFG00000013510; ENSCAFG00030010510; ENSCAFG00040025786; ENSCAFG00845022020; ENSCANG00000030079; ENSCATG00000037133; ENSCCNG00000003127; ENSCSAG00000010111; ENSFCAG00000008220; ENSGGOG00000024394; ENSJJAG00000013846; ENSLAFG00000013257; ENSLCNG00005016477; ENSMFAG00000039629; ENSMICG00000009731; ENSMLEG00000033904; ENSMLUG00000016119; ENSMMMG00000014914; ENSMMUG00000022601; ENSMNEG00000030274; ENSNGAG00000018967; ENSNLEG00000007124; ENSOCUG00000005427; ENSPANG00000009083; ENSPLOG00000007090; ENSPPAG00000042817; ENSPPYG00000013115; ENSPTIG00000011848; ENSPTRG00000043959; ENSRBIG00000040701; ENSRFEG00010020193; ENSRROG00000035316; ENSSDAG00000020160; ENSSSCG00005034714; ENSSSCG00015008370; ENSSSCG00025020324; ENSSSCG00030035186; ENSSSCG00035079382; ENSSSCG00040036512; ENSSSCG00045023175; ENSSSCG00050037141; ENSSSCG00055008554; ENSSSCG00060058264; ENSSSCG00065052126; ENSSSCG00070020566; ENSSSUG00005001816; ENSSTOG00000016482; ENSSVLG00005003093; ENSTGEG00000004249; ENSUAMG00000018783; ENSUMAG00000022656; ENSUPAG00010007984; ENSVVUG00000011892"	"Creb1; CREB1; LOC101356881"	"A0A024R401; A0A096MS95; A0A0D9RCK8; A0A286ZWB0; A0A2I2YCF6; A0A2J8N5U5; A0A2J8WUF2; A0A2K5I9K2; A0A2K5MQP0; A0A2K5X536; A0A2K5X539; A0A2K5YUX5; A0A2K6BKD0; A0A2K6MDT5; A0A2K6Q2B5; A0A2R9CPF8; A0A2U3WAS2; A0A2U3XPQ5; A0A2Y9R2V7; A0A384BST9; A0A3Q7QRU5; A0A3Q7SQX8; A0A452RWS8; A0A4X1V0B9; A0A5E4AFY5; A0A5N4E668; A0A667HEB5; A0A671G6M8; A0A673T0V2; A0A6D2VSK7; A0A6D2WEQ2; A0A6G1BFF3; A0A6I9IA29; A0A6J1YUG6; A0A6J2CMJ0; A0A6J2LK21; A0A6P6GX89; A0A7J7WGC8; A0A7J7XTS6; A0A7J8FQY6; A0A811ZBK8; A0A8B7V7Z4; A0A8B8T0S6; A0A8C0N7M6; A0A8C5KHE0; A0A8C5V357; A0A8C6EUY0; A0A8C6RKM3; A0A8C8WVH7; A0A8C9JRV6; A0A8C9Q947; A0A8D2AN63; A0A8D2EE05; A0A8D2H908; A0A8I3S2U7; A0A8J8XE04; A0A8J8XJ71; A0A8M1M6Z7; aju:106967098; aml:100477711; cang:105517357; caty:105580103; ccan:109691946; cfa:607922; cfr:102508765; csab:103217717; D2H8G8; F7AUB4; G1PTV7; G1R662; G1SNW9; G3TAZ1; G7N8R8; H2P8F2; H2R2Y2; I3MRM5; lav:100675162; lww:102748542; M3W964; mcc:708717; mcf:102141699; mleu:105549382; mlf:102428529; mmur:105864304; myb:102246867; ngi:103744440; ocu:100351999; oro:101383024; pdic:114495167; ptr:459901; Q5U0J5; rbb:108540349; rro:104680220; S7N6N9; tmu:101356881; umr:103659802; vpc:102531048; vvp:112922611; zca:113919503"	"NCAM signaling for neurite out-growth; CREB phosphorylation; CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling; Gastrin-CREB signalling pathway via PKC and MAPK; NGF-stimulated transcription"	"IL-2 signaling pathway; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control; Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Energy metabolism; miRNAs involved in DNA damage response; Folate-alcohol and cancer pathway hypotheses; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling pathway; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; p38 MAPK signaling pathway; EGF/EGFR signaling pathway; G1 to S cell cycle control; Gastrin signaling pathway; CAMKK2 pathway; Galanin receptor pathway; Neuroinflammation and glutamatergic signaling; GDNF signaling; Interferon type I signaling pathways; T-cell receptor signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control"	"49"	"0"	"56.0"	"36.0"	"57.8"	"45.8"	"50.8"	"39.4"	"90.3"	"0.8"	"806.1"	"805.1"	"1900.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33527"	"Multidrug resistance-associated protein 1 OS=Homo sapiens OX=9606 GN=ABCC1 PE=1 SV=3"	"0.000"	""	"4"	"3"	"4"	"3"	"1531"	"171.5"	"7.11"	"319.23"	"10.41"	"1"	"3"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"4363"	"ENSG00000103222; ENSG00000278183"	"ABCC1"	"A3RJX2; C9JPJ4; hsa:4363; O14819; O43333; P33527; P78419; Q59GI9; Q9UQ97; Q9UQ99; Q9UQA0"	"ABC-family proteins mediated transport; Paracetamol ADME; Cytoprotection by HMOX1; Transport of RCbl within the body; Heme degradation; Synthesis of Leukotrienes (LT) and Eoxins (EX)"	"Irinotecan pathway; Leukotriene metabolic pathway; TROP2 regulatory signaling"	"9"	"0"	"0.0"	"0.0"	"0.0"	"2.0"	"2.5"	"0.0"	"3.8"	"2.2"	"101.4"	"105.1"	"261.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6WKZ4"	"Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3"	"0.000"	""	"2"	"3"	"7"	"3"	"1283"	"137.1"	"5.43"	"1812.95"	"10.41"	"3"	"2"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"80223"	"ENSG00000156675"	"RAB11FIP1"	"hsa:80223; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ4; Q6WKZ6; Q86YV4; Q8TDL1; Q9H642"	""	""	"0"	"0"	"49.1"	"35.5"	"60.1"	"74.9"	"104.2"	"244.1"	"601.7"	"8.2"	"1978.0"	"1860.1"	"2722.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2K8"	"Serine/threonine-protein kinase TAO3 OS=Homo sapiens OX=9606 GN=TAOK3 PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"898"	"105.3"	"7.30"	"1124.52"	"10.40"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"51347"	"ENSG00000135090"	"TAOK3"	"hsa:51347; Q658N1; Q8IUM4; Q9H2K8; Q9HC79; Q9NZM9; Q9UHG7"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"MAPK signaling pathway"	"4"	"0"	"13.2"	"3.2"	"15.7"	"12.6"	"13.7"	"14.7"	"36.5"	"0.0"	"1118.6"	"1175.4"	"1979.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49207"	"60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3"	"0.000"	""	"21"	"3"	"6"	"3"	"117"	"13.3"	"11.47"	"1102.83"	"10.38"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01199"	"6164"	"ENSG00000109475"	"RPL34"	"hsa:6164; P49207; Q6FG66; Q9BUZ2"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"148.7"	"184.2"	"135.8"	"122.6"	"107.6"	"124.8"	"1091.1"	"4.1"	"2172.7"	"2317.1"	"3157.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y657"	"Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3"	"0.000"	""	"26"	"4"	"5"	"4"	"262"	"29.6"	"6.96"	"833.88"	"10.38"	"2"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02513"	"10927"	"ENSG00000106723"	"SPIN1"	"A8K0X6; B3KRQ4; hsa:10927; Q7KZJ8; Q9GZT2; Q9H0N7; Q9Y657"	""	""	"0"	"0"	"46.4"	"28.0"	"49.4"	"43.5"	"43.0"	"53.8"	"91.8"	"3.5"	"641.9"	"666.0"	"1392.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2H8"	"Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3 PE=1 SV=1"	"0.000"	""	"12"	"2"	"6"	"2"	"161"	"18.1"	"6.79"	"962.83"	"10.36"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160"	"53938"	"ENSG00000240344"	"PPIL3"	"hsa:53938; Q86WF9; Q96IA9; Q9BXZ1; Q9H2H8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"57.3"	"40.5"	"67.3"	"69.0"	"78.3"	"60.3"	"134.6"	"2.4"	"1037.7"	"1046.4"	"1963.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19404"	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2"	"0.000"	""	"12"	"3"	"5"	"3"	"249"	"27.4"	"8.06"	"577.12"	"10.35"	"2"	"3"	"other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01257"	"4729"	"ENSG00000178127"	"NDUFV2"	"hsa:4729; P19404; Q9BV41"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"56.2"	"46.8"	"54.2"	"47.6"	"67.0"	"64.3"	"86.0"	"0.0"	"645.0"	"631.0"	"1093.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAQ2"	"SWI/SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1"	"0.000"	""	"5"	"4"	"5"	"3"	"1214"	"132.8"	"5.69"	"733.61"	"10.35"	"2"	"3"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6601"	"ENSG00000139613"	"SMARCC2"	"F8VTJ5; hsa:6601; Q59GV3; Q8TAQ2; Q92923; Q96E12; Q96GY4"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome; 10q11.21q11.23 copy number variation syndrome"	"7"	"0"	"26.2"	"16.3"	"26.5"	"17.5"	"20.0"	"16.3"	"35.6"	"2.1"	"306.4"	"273.8"	"619.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EP5"	"DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"3"	"407"	"43.4"	"8.56"	"937.74"	"10.32"	"2"	"3"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"26528"	"ENSG00000071626"	"DAZAP1"	"hsa:26528; Q96EP5; Q96MJ3; Q9NRR9"	""	""	"0"	"0"	"439.9"	"365.1"	"379.7"	"383.1"	"343.3"	"308.0"	"713.6"	"0.6"	"1492.4"	"1661.4"	"2338.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83881"	"60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2"	"0.000"	""	"30"	"5"	"7"	"5"	"106"	"12.4"	"10.58"	"586.29"	"10.30"	"2"	"5"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus"	"other molecular function"	"Pf00935"	"6173"	"ENSG00000241343"	"RPL36A"	"hsa:6173; P09896; P10661; P83881; Q08ES5; Q5J9I6"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"563.1"	"490.0"	"445.4"	"447.2"	"353.5"	"448.7"	"1503.5"	"2.8"	"3079.6"	"2902.6"	"5139.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNH7"	"Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"406"	"46.6"	"6.16"	"981.42"	"10.29"	"2"	"3"	"transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787, Pf09325"	"58533"	"ENSG00000129515"	"SNX6"	"C0H5W9; hsa:58533; Q9UNH7; Q9Y449"	""	""	"0"	"0"	"47.6"	"31.1"	"62.8"	"44.4"	"48.6"	"55.5"	"103.9"	"8.8"	"1622.4"	"1529.5"	"3554.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62861"	"40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1"	"0.000"	""	"20"	"3"	"6"	"3"	"59"	"6.6"	"12.15"	"1054.43"	"10.29"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf04758"	""	"ENSCHIG00000017446; ENSJHYG00000000624; ENSLLEG00000000574"	"Fau; FAU"	"A0A452F0A8; A0A7L0YXB0; A0A8C5IE60; A0A8C5LQJ8; P0C2F0; P62860; P62863; P62864; P62866; P62867; Q05472; Q5RC12; Q8HYI8; Q920W7; Q95261"	""	""	"0"	"0"	"284.5"	"222.9"	"234.1"	"248.5"	"200.5"	"216.8"	"595.0"	"5.0"	"1819.5"	"1603.0"	"4406.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75821"	"Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2"	"0.000"	""	"13"	"2"	"3"	"2"	"320"	"35.6"	"6.13"	"646.47"	"10.28"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12353"	"8666"	"ENSG00000130811"	"EIF3G"	"hsa:8666; O14801; O75821; Q969U5"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"8"	"0"	"50.3"	"43.2"	"53.0"	"43.5"	"40.2"	"48.6"	"60.9"	"0.0"	"245.1"	"238.2"	"724.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAJ7"	"Histone deacetylase complex subunit SAP30L OS=Homo sapiens OX=9606 GN=SAP30L PE=1 SV=1"	"0.000"	""	"17"	"3"	"4"	"3"	"183"	"20.9"	"9.36"	"329.80"	"10.25"	"1"	"3"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"79685"	"ENSG00000164576"	"SAP30L"	"E9PAU7; E9PAY2; hsa:79685; Q9HAJ7"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	""	"3"	"0"	"30.9"	"21.9"	"43.3"	"34.0"	"39.2"	"17.5"	"113.2"	"3.0"	"935.0"	"822.6"	"2218.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15091"	"Mitochondrial ribonuclease P catalytic subunit OS=Homo sapiens OX=9606 GN=PRORP PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"583"	"67.3"	"8.78"	"729.09"	"10.25"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf16953"	"9692"	"ENSG00000100890"	"PRORP"	"B4DXD9; B4E0S8; B4E211; C4AM93; D3DS99; D3DSA1; hsa:9692; O15091; Q86SZ4; Q86YB5; Q8N5L5"	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	""	"3"	"0"	"11.4"	"12.0"	"17.1"	"17.2"	"18.4"	"19.0"	"29.2"	"2.6"	"272.8"	"289.5"	"718.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05048"	"Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1"	"0.000"	""	"9"	"3"	"5"	"3"	"431"	"48.3"	"6.58"	"529.12"	"10.24"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00400, Pf16699"	"1477"	"ENSG00000101138"	"CSTF1"	"hsa:1477; Q05048; Q5QPD8"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"81.0"	"58.1"	"91.8"	"72.0"	"88.6"	"66.4"	"118.3"	"0.0"	"954.7"	"1021.1"	"2331.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96TA2"	"ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"3"	"1"	"773"	"86.4"	"8.76"	"649.47"	"10.23"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00004, Pf01434, Pf17862"	"10730"	"ENSG00000136758"	"YME1L1"	"B4DNM1; D3DRV8; D3DRV9; hsa:10730; Q5T8D9; Q96TA2; Q9H1Q0; Q9UMR9"	"Processing of SMDT1"	""	"1"	"0"	"18.7"	"11.9"	"31.9"	"18.4"	"21.0"	"25.9"	"41.7"	"0.2"	"313.2"	"335.9"	"718.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52756"	"RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"815"	"92.1"	"6.28"	"1162.15"	"10.22"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"10181"	"ENSG00000003756"	"RBM5"	"B2RA45; B4DM16; B4DMF9; B4DZ63; hsa:10181; P52756; Q93021; Q9BU14; Q9HDA6; Q9UKY8; Q9UL24"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"81.2"	"46.5"	"64.1"	"65.1"	"60.6"	"62.5"	"143.7"	"7.2"	"562.3"	"499.6"	"994.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92797"	"Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2"	"0.000"	""	"4"	"4"	"6"	"4"	"1274"	"141.1"	"6.13"	"1063.23"	"10.21"	"3"	"3"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf11935, Pf12295"	"8189"	"ENSG00000125755"	"SYMPK"	"hsa:8189; O00521; O00689; O00733; Q59GT5; Q8N2U5; Q92797"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	""	"5"	"0"	"28.5"	"28.8"	"35.9"	"31.7"	"24.9"	"29.2"	"54.5"	"1.8"	"489.2"	"564.8"	"1039.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ES7"	"SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"293"	"33.2"	"8.10"	"573.07"	"10.20"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07039"	"112869"	"ENSG00000176476"	"SGF29"	"hsa:112869; Q96ES7; Q96MF5"	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	""	"2"	"0"	"24.4"	"18.5"	"25.3"	"27.8"	"22.4"	"29.3"	"39.3"	"0.0"	"337.2"	"325.4"	"577.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWZ3"	"Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1"	"0.000"	""	"1"	"3"	"4"	"1"	"2542"	"269.3"	"5.73"	"413.94"	"10.20"	"1"	"3"	"stress response"	"other cell component"	""	"Pf00013, Pf12796"	"404734; 54882"	"ENSG00000131503"	"ANKHD1"	"A6NH85; hsa:404734; hsa:54882; Q149P2; Q8IWZ2; Q8IWZ3; Q8WY90; Q96G77; Q96GK0; Q9H2U0; Q9HA95; Q9NWG4; Q9UPR7"	""	""	"0"	"0"	"12.6"	"3.7"	"12.3"	"9.2"	"10.8"	"6.4"	"19.4"	"0.0"	"254.4"	"231.1"	"728.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75940"	"Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"238"	"26.7"	"7.24"	"1071.24"	"10.18"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06003"	"10285"	"ENSG00000119953"	"SMNDC1"	"B2RA27; D3DRB1; hsa:10285; O75940; Q5T3K6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"62.4"	"38.4"	"41.7"	"47.8"	"38.6"	"48.1"	"84.5"	"1.4"	"296.0"	"256.2"	"562.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZJ9"	"Diphosphoinositol polyphosphate phosphohydrolase 2 OS=Homo sapiens OX=9606 GN=NUDT4 PE=1 SV=2"	"0.000"	""	"18"	"4"	"6"	"1"	"180"	"20.3"	"6.35"	"1148.09"	"10.18"	"3"	"3"	"other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11163"	"ENSG00000173598"	"NUDT4"	"B7Z916; hsa:11163; Q4AEJ6; Q53EZ2; Q68DD7; Q9NPC5; Q9NS30; Q9NZJ9; Q9NZK0; Q9NZK1"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"3"	"41.8"	"46.7"	"97.4"	"169.4"	"310.0"	"498.3"	"1626.9"	"0.0"	"3996.7"	"3999.1"	"5254.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPX5"	"Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1"	"0.000"	""	"22"	"3"	"4"	"2"	"153"	"16.9"	"6.60"	"415.27"	"10.12"	"1"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf04699"	"81873"	"ENSG00000136950"	"ARPC5L"	"hsa:81873; Q7Z523; Q9BPX5"	""	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"2"	"0"	"12.6"	"12.4"	"7.8"	"15.8"	"13.5"	"17.8"	"23.4"	"3.0"	"296.6"	"321.8"	"917.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08J23"	"RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"767"	"86.4"	"6.77"	"1093.20"	"10.11"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01189"	"54888"	"ENSG00000037474"	"NSUN2"	"A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; hsa:54888; Q08J23; Q9BVN4; Q9H858; Q9NXD9"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"83.8"	"60.2"	"80.1"	"69.7"	"69.7"	"67.2"	"98.2"	"1.1"	"270.2"	"257.5"	"482.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDN4"	"CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens OX=9606 GN=CABLES1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"633"	"67.6"	"9.17"	"982.01"	"10.11"	"2"	"3"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf00134"	"91768"	"ENSG00000134508"	"CABLES1"	"B4DK60; hsa:91768; Q8N3Y8; Q8NA22; Q8TDN4; Q9BTG1"	"Factors involved in megakaryocyte development and platelet production; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	""	"3"	"0"	"4.1"	"0.0"	"4.9"	"2.9"	"3.3"	"4.0"	"16.3"	"3.0"	"189.8"	"173.8"	"326.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14562"	"Ubiquitin domain-containing protein UBFD1 OS=Homo sapiens OX=9606 GN=UBFD1 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"309"	"33.4"	"5.77"	"894.98"	"10.09"	"2"	"2"	""	""	""	"Pf00240"	"56061"	"ENSG00000103353"	"UBFD1"	"A8MW58; D3DWF2; hsa:56061; O14562"	""	""	"0"	"0"	"13.2"	"11.7"	"27.3"	"19.2"	"15.4"	"19.6"	"31.3"	"0.0"	"763.9"	"807.5"	"1521.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FF9"	"Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1"	"0.000"	""	"13"	"3"	"9"	"3"	"252"	"27.6"	"9.61"	"1377.93"	"10.08"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09666"	"113130"	"ENSG00000146670"	"CDCA5"	"A8K625; hsa:113130; Q96FF9"	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Establishment of Sister Chromatid Cohesion"	""	"3"	"0"	"185.3"	"150.6"	"187.2"	"175.6"	"155.8"	"171.4"	"518.6"	"3.4"	"1437.2"	"1458.1"	"2656.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49411"	"Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2"	"0.000"	""	"12"	"4"	"6"	"4"	"452"	"49.5"	"7.61"	"1203.15"	"10.07"	"3"	"3"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"100.4"	"71.8"	"102.0"	"108.6"	"110.4"	"83.1"	"174.2"	"9.4"	"1115.8"	"1091.1"	"2338.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08779"	"Keratin, type I cytoskeletal 16 OS=Homo sapiens OX=9606 GN=KRT16 PE=1 SV=4"	"0.000"	""	"7"	"4"	"8"	"1"	"473"	"51.2"	"5.05"	"1193.88"	"10.06"	"4"	"4"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3868"	"ENSG00000186832"	"KRT16"	"A8K488; hsa:3868; P08779; P30654; Q16402; Q9UBG8"	"Formation of the cornified envelope"	"Vitamin D receptor pathway"	"3"	"0"	"14.9"	"392.1"	"28.1"	"54.1"	"16.3"	"267.8"	"74.3"	"13.2"	"180.4"	"208.1"	"182.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14166"	"Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"644"	"74.4"	"5.53"	"461.94"	"10.05"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	"23170"	"ENSG00000100304"	"TTLL12"	"hsa:23170; Q14166; Q20WK5; Q9UGU3"	"Carboxyterminal post-translational modifications of tubulin"	""	"1"	"0"	"57.6"	"56.9"	"70.5"	"71.5"	"79.4"	"69.9"	"122.6"	"0.0"	"418.6"	"422.8"	"783.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAV0"	"Protein FAM76A OS=Homo sapiens OX=9606 GN=FAM76A PE=2 SV=1"	"0.000"	""	"11"	"4"	"5"	"2"	"307"	"35.0"	"9.19"	"593.56"	"10.04"	"2"	"3"	""	"nucleus"	""	"Pf16046"	"199870"	"ENSG00000009780"	"FAM76A"	"B4DWT3; hsa:199870; O95565; O95566; Q8N7J5; Q8TAV0"	""	""	"0"	"2"	"68.9"	"62.3"	"67.5"	"78.2"	"78.4"	"63.6"	"225.0"	"0.0"	"2519.6"	"2515.9"	"4466.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09972"	"Fructose-bisphosphate aldolase C OS=Homo sapiens OX=9606 GN=ALDOC PE=1 SV=2"	"0.000"	""	"17"	"5"	"6"	"1"	"364"	"39.4"	"6.87"	"800.49"	"10.02"	"3"	"3"	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"230"	"ENSG00000109107"	"ALDOC"	"B2R5R3; hsa:230; P09972; Q3SYL3; Q6FH94; Q6P0L5"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis"	"Clear cell renal cell carcinoma pathways; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7N4"	"Splicing factor, arginine/serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3"	"0.000"	""	"3"	"3"	"6"	"2"	"1312"	"139.2"	"9.25"	"1086.97"	"10.01"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"58506"	"ENSG00000126461"	"SCAF1"	"hsa:58506; Q7Z5V7; Q8WVA1; Q9H7N4; Q9NR59"	""	""	"0"	"0"	"105.6"	"71.9"	"112.0"	"95.6"	"87.2"	"90.0"	"273.9"	"12.9"	"672.1"	"625.7"	"1120.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRD0"	"BUD13 homolog OS=Homo sapiens OX=9606 GN=BUD13 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"619"	"70.5"	"9.86"	"993.77"	"10.01"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf09736"	"84811"	"ENSG00000137656"	"BUD13"	"A8K0S0; hsa:84811; Q96LS7; Q9BRD0"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"33.8"	"29.3"	"29.3"	"33.9"	"27.1"	"31.2"	"90.8"	"0.0"	"444.0"	"458.2"	"821.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13098"	"COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4"	"0.000"	""	"7"	"2"	"3"	"2"	"491"	"55.5"	"6.74"	"575.29"	"10.01"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf10602"	"2873"	"ENSG00000169727"	"GPS1"	"hsa:2873; Q13098; Q8NA10; Q9BWL1"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	""	"5"	"0"	"22.7"	"16.4"	"19.8"	"25.5"	"19.6"	"16.1"	"25.6"	"1.0"	"217.2"	"218.2"	"641.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00231"	"26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3"	""	""	"10"	"3"	"3"	"3"	"422"	"47.4"	"6.48"	""	"9.99"	""	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18055, Pf18503"	"5717"	"ENSG00000108671"	"PSMD11"	"A8K3I7; E1P663; hsa:5717; O00231; O00495; Q53FT5"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling"	"63"	"0"	"31.7"	"24.5"	"34.8"	"27.8"	"36.7"	"33.9"	"65.7"	"7.9"	"411.7"	"489.4"	"1317.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40429"	"60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2"	"0.000"	""	"13"	"3"	"6"	"3"	"203"	"23.6"	"10.93"	"874.29"	"9.96"	"3"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"23521"	"ENSG00000142541"	"RPL13A"	"A8K505; hsa:23521; P40429"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"94.3"	"85.1"	"109.2"	"106.2"	"84.1"	"100.0"	"472.8"	"0.7"	"1533.9"	"1560.8"	"2547.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZS3"	"WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"305"	"33.6"	"5.47"	"425.36"	"9.95"	"1"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"80349"	"ENSG00000140395"	"SKIC8"	"D3DW84; hsa:80349; Q6IA22; Q7Z4X4; Q9GZS3"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; mRNA decay by 3' to 5' exoribonuclease"	""	"5"	"0"	"29.4"	"19.3"	"30.4"	"33.5"	"29.1"	"28.4"	"56.9"	"0.0"	"434.9"	"461.7"	"1148.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZF9"	"Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2"	"0.000"	""	"2"	"4"	"6"	"3"	"1416"	"162.4"	"7.03"	"884.88"	"9.93"	"3"	"3"	"other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf12796"	"55075"	"ENSG00000137831"	"UACA"	"G3XAG2; hsa:55075; Q14DD3; Q8N3B8; Q96NH6; Q9BZF9; Q9HCL1; Q9NWC6"	"Regulation of the apoptosome activity; RHOH GTPase cycle"	""	"2"	"0"	"25.7"	"23.9"	"34.0"	"30.2"	"36.5"	"44.5"	"92.5"	"0.0"	"1042.5"	"988.9"	"1812.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUD4"	"Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1"	"0.000"	""	"20"	"2"	"3"	"2"	"166"	"19.2"	"7.34"	"245.36"	"9.92"	"1"	"2"	""	"nucleus"	""	"Pf08315"	"151903"	"ENSG00000160799"	"CCDC12"	"hsa:151903; Q8N8I4; Q8WUD4"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"21.0"	"15.7"	"27.6"	"19.9"	"14.5"	"19.9"	"67.9"	"1.2"	"375.5"	"349.5"	"685.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50502"	"Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2"	"0.000"	""	"7"	"3"	"6"	"3"	"369"	"41.3"	"5.27"	"983.81"	"9.91"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf17830, Pf18253"	"6767"	"ENSG00000100380"	"ST13"	"hsa:6767; O14999; P50502; Q2TU77"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"327.2"	"266.4"	"366.5"	"319.6"	"358.8"	"249.5"	"402.9"	"3.6"	"1659.1"	"1599.7"	"2676.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SK2"	"Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"561"	"62.9"	"8.63"	"478.07"	"9.89"	"1"	"2"	""	"other membranes"	""	"Pf09786"	"84928"	"ENSG00000146842"	"TMEM209"	"A4D1L1; hsa:84928; Q49A50; Q6PF00; Q8NCH3; Q96SK2; Q96SL6"	""	""	"0"	"0"	"40.7"	"43.9"	"27.0"	"38.1"	"27.6"	"50.4"	"74.3"	"0.9"	"359.8"	"345.5"	"585.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYI3"	"Hyccin OS=Homo sapiens OX=9606 GN=FAM126A PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"521"	"57.6"	"8.16"	"982.67"	"9.88"	"3"	"3"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09790"	"84668"	"ENSG00000122591"	"HYCC1"	"A0A024RA06; A4D145; B8ZZJ1; hsa:84668; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6; Q9BYI3"	""	""	"0"	"0"	"43.0"	"25.8"	"36.2"	"29.4"	"26.8"	"35.0"	"62.9"	"1.1"	"646.2"	"595.3"	"1179.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46781"	"40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3"	"0.000"	""	"15"	"4"	"7"	"4"	"194"	"22.6"	"10.65"	"1614.36"	"9.88"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00163, Pf01479"	"6203"	"ENSG00000170889; ENSG00000274005; ENSG00000274626; ENSG00000274646; ENSG00000274950; ENSG00000275323; ENSG00000277079; ENSG00000277359; ENSG00000278081; ENSG00000278270"	"RPS9"	"A9C4C1; hsa:6203; P46781; Q4QRK7; Q9BVZ0"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"20"	"0"	"110.0"	"98.4"	"135.7"	"107.7"	"114.4"	"123.2"	"430.5"	"0.0"	"1933.7"	"2099.6"	"3849.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47756"	"F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4"	"0.000"	""	"12"	"3"	"5"	"3"	"277"	"31.3"	"5.59"	"600.71"	"9.87"	"2"	"3"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01115"	"100612860; 101140941"	"ENSGGOG00000003982; ENSPPYG00000001789; ENSPTRG00000000268"	"CAPZB"	"A0A2J8KEQ9; A0A2J8T2J3; A0A6D2W7V0; A0A6D2XKL1; A0A8B6ZIG4; A0A9B0TL78; G3QN07; H2N8T0; H2R9E0"	""	""	"0"	"0"	"48.8"	"28.1"	"58.4"	"52.7"	"57.5"	"52.1"	"109.1"	"2.0"	"991.8"	"1016.6"	"2066.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQR0"	"Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1"	"0.000"	""	"6"	"3"	"5"	"3"	"700"	"77.2"	"8.54"	"710.74"	"9.86"	"2"	"3"	"other biological processes"	"nucleus"	""	"Pf00536, Pf02820, Pf12140, Pf17208"	"10389"	"ENSG00000102098"	"SCML2"	"hsa:10389; Q5JXE6; Q86U98; Q8IWD0; Q8NDP2; Q9UGC5; Q9UQR0"	""	""	"0"	"0"	"84.1"	"59.6"	"83.7"	"70.2"	"71.2"	"67.3"	"138.3"	"8.1"	"648.7"	"615.6"	"1360.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92796"	"Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"2"	"817"	"90.3"	"7.03"	"561.20"	"9.85"	"2"	"3"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf10600"	"1741"	"ENSG00000082458"	"DLG3"	"B4E0H1; D3DVU5; hsa:1741; Q5JUW6; Q5JUW7; Q92796; Q9ULI8"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Neurexins and neuroligins; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	""	"10"	"0"	"7.4"	"3.5"	"10.3"	"6.0"	"10.3"	"7.0"	"19.1"	"1.5"	"119.8"	"137.6"	"231.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15436"	"Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"765"	"86.1"	"7.08"	"952.28"	"9.84"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10484"	"ENSG00000100934"	"SEC23A"	"B2R5P4; B3KXI2; hsa:10484; Q15436; Q8NE16"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; SARS-CoV-2 activates/modulates innate and adaptive immune responses; MHC class II antigen presentation; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"7"	"0"	"27.6"	"25.8"	"48.3"	"32.1"	"38.4"	"38.0"	"72.6"	"2.2"	"340.1"	"335.9"	"745.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUJ2"	"Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"856"	"95.7"	"6.92"	"926.89"	"9.81"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00622, Pf02037, Pf13671"	"11100"	"ENSG00000105323"	"HNRNPUL1"	"B3KMW7; hsa:11100; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9BUJ2; Q9HAL3; Q9UG75"	""	""	"0"	"0"	"55.0"	"46.3"	"50.8"	"52.3"	"50.6"	"46.1"	"81.6"	"0.7"	"186.2"	"160.8"	"309.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75947"	"ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3"	"0.000"	""	"24"	"2"	"3"	"2"	"161"	"18.5"	"5.30"	"434.45"	"9.79"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05873"	"10476"	"ENSG00000167863"	"ATP5PD"	"B2R5L6; hsa:10476; O75947; Q9H3J4"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"11.2"	"12.3"	"13.0"	"10.0"	"14.6"	"10.4"	"23.7"	"1.0"	"333.5"	"328.2"	"686.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVY7"	"Ubiquitin-like domain-containing CTD phosphatase 1 OS=Homo sapiens OX=9606 GN=UBLCP1 PE=1 SV=2"	"0.000"	""	"14"	"4"	"7"	"4"	"318"	"36.8"	"6.46"	"1720.63"	"9.79"	"4"	"3"	"protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00240, Pf03031"	"134510"	"ENSG00000164332"	"UBLCP1"	"D3DQJ7; hsa:134510; Q8WVY7; Q96DK5"	""	""	"0"	"0"	"28.0"	"19.0"	"43.7"	"41.6"	"42.8"	"40.3"	"41.3"	"3.1"	"2612.2"	"2738.5"	"5218.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37198"	"Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"2"	"522"	"53.2"	"5.31"	"1004.81"	"9.73"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05064"	"23636"	"ENSG00000213024"	"NUP62"	"B3KWU5; hsa:23636; P37198; Q503A4; Q6GTM2; Q96C43; Q9NSL1"	"Nuclear Pore Complex (NPC) Disassembly; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"7q11.23 copy number variation syndrome"	"30"	"0"	"25.3"	"18.9"	"30.0"	"26.6"	"26.2"	"26.8"	"61.4"	"0.0"	"531.2"	"588.3"	"1180.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82650"	"28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"360"	"41.3"	"7.90"	"970.74"	"9.73"	"3"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10245"	"56945"	"ENSG00000175110"	"MRPS22"	"hsa:56945; P82650; Q9H3I1"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"Primary ovarian insufficiency"	"4"	"0"	"106.6"	"78.8"	"100.3"	"78.8"	"124.3"	"97.2"	"194.9"	"0.0"	"537.8"	"529.6"	"881.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51572"	"B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3"	"0.000"	""	"11"	"3"	"6"	"3"	"246"	"28.0"	"8.44"	"998.88"	"9.72"	"3"	"3"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05529, Pf18035"	"10134"	"ENSG00000185825"	"BCAP31"	"B3KQ79; D3DWV5; hsa:10134; P51572; Q13836; Q96CF0"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; RHOA GTPase cycle; Apoptotic cleavage of cellular proteins"	""	"4"	"0"	"156.3"	"129.9"	"153.9"	"139.5"	"121.5"	"169.8"	"262.9"	"0.0"	"931.6"	"932.5"	"1651.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15067"	"Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"660"	"74.4"	"8.16"	"481.70"	"9.72"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770, Pf14749"	"51"	"ENSG00000161533"	"ACOX1"	"A8K6X8; A8KAA0; B4DK61; F5GYQ8; hsa:51; Q12863; Q15067; Q15068; Q15101; Q16131; Q7Z3W5; Q9UD31"	"TYSND1 cleaves peroxisomal proteins"	"Estrogen receptor pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"8"	"0"	"15.3"	"15.7"	"18.9"	"19.8"	"12.2"	"17.8"	"24.8"	"0.0"	"283.1"	"331.0"	"649.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYV4"	"Cyclin-dependent kinase 12 OS=Homo sapiens OX=9606 GN=CDK12 PE=1 SV=2"	"0.000"	""	"2"	"3"	"5"	"3"	"1490"	"164.1"	"9.44"	"565.91"	"9.71"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"51755"	"ENSG00000167258"	"CDK12"	"A7E2B2; B4DYX4; B9EIQ6; hsa:51755; O94978; Q9NYV4"	"TP53 Regulates Transcription of DNA Repair Genes"	"17q12 copy number variation syndrome"	"2"	"0"	"107.2"	"64.7"	"111.4"	"98.9"	"90.6"	"91.3"	"188.2"	"0.0"	"811.6"	"814.1"	"1773.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27986"	"Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Homo sapiens OX=9606 GN=PIK3R1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"724"	"83.5"	"6.16"	"828.03"	"9.70"	"2"	"2"	"cell adhesion;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00620, Pf16454"	"5295"	"ENSG00000145675"	"PIK3R1"	"B3KT19; D3DWA0; E7EX19; hsa:5295; P27986; Q15747; Q4VBZ7; Q53EM6; Q8IXA2; Q8N1C5"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; RHOJ GTPase cycle; Role of phospholipids in phagocytosis; Role of LAT2/NTAL/LAB on calcium mobilization; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Downstream TCR signaling; RND2 GTPase cycle; RHOG GTPase cycle; G alpha (q) signalling events; RHOD GTPase cycle; RHOF GTPase cycle; Extra-nuclear estrogen signaling; RHOV GTPase cycle; PIP3 activates AKT signaling; Signaling by ALK fusions and activated point mutants; RHOU GTPase cycle; Synthesis of PIPs at the plasma membrane; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RET signaling; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); Interleukin receptor SHC signaling; Regulation of signaling by CBL; Nephrin family interactions; RAF/MAP kinase cascade; PI3K Cascade; GPVI-mediated activation cascade; Interleukin-7 signaling; Signaling by SCF-KIT; Downstream signal transduction; PI3K/AKT activation; Signaling by ALK; Tie2 Signaling; DAP12 signaling; Costimulation by the CD28 family; CD28 dependent PI3K/Akt signaling; VEGFA-VEGFR2 Pathway; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; RND3 GTPase cycle; RND1 GTPase cycle; Interleukin-4 and Interleukin-13 signaling; PI3K events in ERBB4 signaling; PI3K events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; PI-3K cascade:FGFR2; Signaling by FGFR2 in disease; PI-3K cascade:FGFR3; PI-3K cascade:FGFR4; Signaling by FGFR3 in disease; FLT3 Signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; Signaling by FLT3 fusion proteins; Signaling by FLT3 ITD and TKD mutants; GP1b-IX-V activation signalling; MET activates PI3K/AKT signaling; Activated NTRK3 signals through PI3K; Activated NTRK2 signals through PI3K"	"IL-5 signaling pathway; Androgen receptor signaling pathway; AMP-activated protein kinase signaling; MicroRNAs in cardiomyocyte hypertrophy; IL-1 signaling pathway; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-9 signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Apoptosis; Bladder cancer; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Microglia pathogen phagocytosis pathway; IL-4 signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Overview of interferons-mediated signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Cancer immunotherapy by CTLA4 blockade; Measles virus infection; Small cell lung cancer; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; IL-18 signaling pathway; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; mBDNF and proBDNF regulation of GABA neurotransmission; IL-2 signaling pathway; Modulators of TCR signaling and T cell activation; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; Interferon type I signaling pathways; Notch signaling pathway; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"150"	"0"	"26.0"	"16.9"	"28.6"	"28.7"	"31.7"	"26.7"	"54.5"	"0.0"	"505.0"	"448.3"	"984.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60884"	"DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1"	"0.000"	""	"9"	"3"	"5"	"3"	"412"	"45.7"	"6.48"	"686.18"	"9.70"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf00226, Pf00684, Pf01556"	"10294"	"ENSG00000069345"	"DNAJA2"	"B2R7L7; hsa:10294; O14711; O60884"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	""	"1"	"0"	"98.3"	"74.7"	"96.0"	"87.3"	"56.2"	"85.0"	"169.6"	"0.0"	"1146.0"	"1236.0"	"2221.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14643"	"Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3"	"0.000"	""	"1"	"4"	"6"	"1"	"2758"	"313.7"	"6.04"	"857.30"	"9.68"	"3"	"3"	"cell-cell signaling;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3708"	"ENSG00000150995"	"ITPR1"	"E7EPX7; E9PDE9; hsa:3708; Q14643; Q14660; Q99897"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; cGMP effects; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; G protein signaling pathways; Cell-type dependent selectivity of CCK2R signaling; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Vitamin D-sensitive calcium signaling in depression; PKC-gamma calcium signaling pathway in ataxia; Type I collagen synthesis in the context of osteogenesis imperfecta; GPR143 in melanocytes and retinal pigment epithelium cells; STING pathway in Kawasaki-like disease and COVID-19; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells; 15q25 copy number variation; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"34"	"0"	"7.8"	"4.8"	"7.0"	"8.6"	"5.1"	"6.2"	"10.1"	"1.4"	"111.5"	"110.3"	"230.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36954"	"DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1"	"0.000"	""	"37"	"3"	"4"	"3"	"125"	"14.5"	"5.14"	"345.98"	"9.68"	"1"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf02150"	"5438"	"ENSG00000105258"	"POLR2I"	"B2R5J2; hsa:5438; P36954; Q6NW05"	"mRNA Splicing - Major Pathway; Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Inhibition of DNA recombination at telomere; PIWI-interacting RNA (piRNA) biogenesis; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; MicroRNA (miRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"60.9"	"49.9"	"62.4"	"71.3"	"65.4"	"32.6"	"104.5"	"1.4"	"333.1"	"291.7"	"631.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51948"	"CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1"	"0.000"	""	"12"	"2"	"3"	"2"	"309"	"35.8"	"6.09"	"274.88"	"9.66"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"enzyme regulator activity;other molecular function"	"Pf06391, Pf17121"	"4331"	"ENSG00000020426"	"MNAT1"	"G3V1U8; hsa:4331; P51948; Q15817; Q6ICQ7"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"38"	"0"	"10.1"	"12.1"	"20.3"	"12.8"	"18.2"	"14.9"	"26.5"	"1.0"	"180.9"	"199.9"	"334.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HS1"	"Serine/threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2"	"0.000"	""	"9"	"2"	"6"	"2"	"289"	"32.0"	"8.68"	"1021.11"	"9.62"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00300"	"192111"	"ENSG00000247077"	"PGAM5"	"A9LN06; C9IZY7; hsa:192111; Q96HS1; Q96JB0"	""	"NRF2-ARE regulation"	"1"	"0"	"43.5"	"32.7"	"46.7"	"35.5"	"27.8"	"40.6"	"137.9"	"4.1"	"1035.4"	"1148.2"	"2005.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62910"	"60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2"	"0.000"	""	"30"	"4"	"7"	"4"	"135"	"15.9"	"11.33"	"1214.79"	"9.58"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01655"	"6161"	"ENSG00000144713"	"RPL32"	"B2R4Q3; hsa:6161; P02433; P62910"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"169.5"	"163.2"	"192.2"	"144.3"	"141.5"	"176.0"	"747.1"	"7.6"	"2110.4"	"2160.7"	"3404.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95182"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3"	"0.000"	""	"24"	"2"	"4"	"2"	"113"	"12.5"	"10.18"	"990.68"	"9.58"	"2"	"2"	"protein metabolism;other metabolic processes;transport"	"other membranes;mitochondrion;translational apparatus"	"transporter activity;other molecular function"	"Pf07347"	"4701"	"ENSG00000267855"	"NDUFA7"	"hsa:4701; O95182"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"58.0"	"49.4"	"47.8"	"63.2"	"54.0"	"57.1"	"106.3"	"0.0"	"557.9"	"639.1"	"1009.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57060"	"RWD domain-containing protein 2B OS=Homo sapiens OX=9606 GN=RWDD2B PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"319"	"36.3"	"5.87"	"946.92"	"9.57"	"2"	"2"	""	""	""	"Pf05773, Pf06544"	"10069"	"ENSG00000156253"	"RWDD2B"	"hsa:10069; P57060"	""	""	"0"	"0"	"4.7"	"0.0"	"7.7"	"2.5"	"7.6"	"8.0"	"17.5"	"2.2"	"225.1"	"228.5"	"305.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16656"	"Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"4"	"1"	"503"	"53.5"	"5.05"	"1070.29"	"9.56"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10491"	"4899"	"ENSG00000106459"	"NRF1"	"A8K4C6; B4DDV6; hsa:4899; Q15305; Q16656; Q96AN2"	"PPARA activates gene expression; Transcriptional activation of mitochondrial biogenesis"	"Energy metabolism; Interactions between LOXL4 and oxidative stress pathway; Mitochondrial gene expression; Sildenafil treatment"	"6"	"0"	"37.0"	"26.0"	"33.8"	"30.8"	"27.9"	"14.5"	"50.3"	"1.3"	"302.5"	"341.6"	"990.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00471"	"Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1"	"0.000"	""	"5"	"3"	"5"	"2"	"708"	"81.8"	"6.71"	"595.75"	"9.54"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf07393"	"10640"	"ENSG00000070367"	"EXOC5"	"B2R6C5; hsa:10640; O00471; Q8IW24"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"Ciliary landscape"	"4"	"0"	"8.2"	"7.2"	"14.5"	"14.0"	"11.4"	"11.3"	"27.0"	"0.0"	"441.4"	"425.0"	"777.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16795"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"377"	"42.5"	"9.80"	"541.14"	"9.51"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01370"	"4704"	"ENSG00000139180"	"NDUFA9"	"hsa:4704; Q14076; Q16795; Q2NKX0"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"6"	"0"	"12.8"	"10.9"	"20.5"	"11.3"	"16.0"	"15.6"	"44.6"	"3.5"	"298.6"	"291.2"	"566.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61254"	"60S ribosomal protein L26 OS=Homo sapiens OX=9606 GN=RPL26 PE=1 SV=1"	"0.000"	""	"28"	"5"	"8"	"5"	"145"	"17.2"	"10.55"	"1647.39"	"9.51"	"5"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"6154"	"ENSG00000161970"	"RPL26"	"B2R4F0; D3DTR8; hsa:6154; P61254; Q02877; Q6IPY2"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"15"	"0"	"223.1"	"204.7"	"223.3"	"201.4"	"180.2"	"226.5"	"769.6"	"2.9"	"1822.5"	"1866.4"	"2782.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KR1"	"Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2"	"0.000"	""	"3"	"4"	"6"	"4"	"1074"	"116.9"	"9.04"	"1807.92"	"9.50"	"4"	"2"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07528, Pf12874"	"51663"	"ENSG00000056097"	"ZFR"	"B2RNR5; hsa:51663; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q96KR1; Q9H6V4; Q9NTI1; Q9Y687"	""	"Exercise-induced circadian regulation"	"1"	"0"	"452.4"	"365.1"	"447.6"	"407.6"	"372.9"	"435.2"	"978.3"	"0.3"	"2008.3"	"1971.0"	"3350.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13601"	"KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4"	"0.000"	""	"9"	"4"	"7"	"4"	"381"	"43.6"	"9.77"	"1735.81"	"9.48"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf17903"	"11103"	"ENSG00000111615"	"KRR1"	"A0FIK6; A0JLP0; B2R989; E7EUQ0; hsa:11103; Q13601; Q8NEA8; Q8TC37; Q96AT5"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"165.9"	"156.7"	"179.4"	"168.1"	"157.0"	"179.5"	"390.7"	"1.2"	"1770.6"	"1860.6"	"3285.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00151"	"PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4"	"0.000"	""	"11"	"3"	"5"	"3"	"329"	"36.0"	"7.02"	"745.69"	"9.48"	"2"	"3"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"9124"	"ENSG00000107438"	"PDLIM1"	"B2RBS6; hsa:9124; O00151; Q5VZH5; Q9BPZ9"	""	""	"0"	"0"	"31.4"	"31.2"	"33.6"	"31.9"	"32.0"	"25.8"	"55.4"	"2.4"	"411.9"	"423.1"	"1088.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14854"	"Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2"	"0.000"	""	"49"	"2"	"3"	"2"	"86"	"10.2"	"7.05"	"317.64"	"9.47"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02297"	"1340"	"ENSG00000126267"	"COX6B1"	"B2R5C9; hsa:1340; P14854; Q6IBL4"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"7"	"0"	"35.8"	"45.1"	"27.2"	"31.4"	"29.8"	"8.1"	"47.1"	"3.0"	"166.1"	"160.5"	"341.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNY4"	"Transcription termination factor 2 OS=Homo sapiens OX=9606 GN=TTF2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"4"	"1"	"1162"	"129.5"	"8.37"	"931.47"	"9.44"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf06839"	"8458"	"ENSG00000116830"	"TTF2"	"A8K4Q2; hsa:8458; O75921; Q5T2K7; Q5VVU8; Q8N6I8; Q9UNY4"	""	"Thyroid stimulating hormone (TSH) signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	"2"	"0"	"21.0"	"12.0"	"21.4"	"21.5"	"19.8"	"19.4"	"41.6"	"0.8"	"181.2"	"181.5"	"278.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQN3"	"Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B PE=1 SV=1"	"0.000"	""	"12"	"3"	"6"	"3"	"213"	"23.9"	"8.76"	"1063.71"	"9.43"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"25978"	"ENSG00000083937"	"CHMP2B"	"B4DJG8; hsa:25978; Q53HC7; Q9UQN3; Q9Y4U6"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III; Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	""	"9"	"0"	"118.5"	"84.8"	"124.8"	"121.5"	"108.0"	"126.1"	"268.2"	"0.0"	"1395.0"	"1410.0"	"2762.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54578"	"Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"494"	"56.0"	"5.30"	"837.78"	"9.43"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00443"	"9097"	"ENSG00000101557"	"USP14"	"B7Z4N8; hsa:9097; J3QRZ5; P54578; Q53XY5"	"Ub-specific processing proteases; Regulation of NF-kappa B signaling"	""	"2"	"0"	"27.2"	"17.7"	"27.9"	"31.3"	"40.3"	"25.0"	"41.1"	"2.3"	"399.7"	"380.0"	"1172.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86SE5"	"RNA-binding Raly-like protein OS=Homo sapiens OX=9606 GN=RALYL PE=1 SV=2"	"0.000"	""	"9"	"3"	"5"	"1"	"291"	"32.3"	"7.93"	"646.47"	"9.42"	"2"	"3"	""	"nucleus"	"other molecular function"	"Pf00076"	"138046"	"ENSG00000184672"	"RALYL"	"B3KTH2; G3V129; hsa:138046; Q6ZW87; Q86SE5; Q8N1C2"	""	""	"0"	"0"	"15.8"	"14.0"	"19.5"	"12.7"	"16.8"	"17.1"	"33.4"	"0.0"	"167.3"	"165.6"	"271.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09110"	"3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"4"	"2"	"424"	"44.3"	"8.44"	"1067.23"	"9.41"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"30"	"ENSG00000060971"	"ACAA1"	"G5E935; hsa:30; P09110; Q96CA6"	"Neutrophil degranulation; TYSND1 cleaves peroxisomal proteins; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of very long chain fatty acids"	"PPAR-alpha pathway; Nuclear receptors meta-pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX)"	"11"	"0"	"48.8"	"33.6"	"64.7"	"42.3"	"39.0"	"43.4"	"77.1"	"1.2"	"435.9"	"403.1"	"951.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14344"	"Guanine nucleotide-binding protein subunit alpha-13 OS=Homo sapiens OX=9606 GN=GNA13 PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"2"	"377"	"44.0"	"8.00"	"907.70"	"9.39"	"3"	"3"	"stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00503"	"10672"	"ENSG00000120063"	"GNA13"	"B2R977; B7Z7R0; F5H1G8; hsa:10672; Q14344; Q8TD70"	"Thrombin signalling through proteinase activated receptors (PARs); Thromboxane signalling through TP receptor; G alpha (12/13) signalling events; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK"	"Thyroid stimulating hormone (TSH) signaling pathway; G protein signaling pathways; Modulators of TCR signaling and T cell activation; Regulation of actin cytoskeleton; G13 signaling pathway"	"11"	"0"	"37.0"	"26.9"	"38.0"	"40.4"	"35.7"	"37.3"	"61.4"	"0.4"	"531.9"	"619.8"	"1142.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93074"	"Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4"	"0.000"	""	"2"	"3"	"4"	"3"	"2177"	"242.9"	"7.05"	"362.57"	"9.38"	"1"	"3"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09497, Pf12144, Pf12145"	"9968"	"ENSG00000184634"	"MED12"	"hsa:9968; O15410; O75557; Q93074; Q9UHV6; Q9UND7"	"Transcriptional regulation of white adipocyte differentiation; PPARA activates gene expression; Generic Transcription Pathway"	""	"3"	"0"	"10.8"	"9.4"	"12.4"	"15.6"	"13.7"	"9.4"	"34.1"	"0.0"	"235.3"	"247.6"	"510.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16537"	"Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform OS=Homo sapiens OX=9606 GN=PPP2R5E PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"467"	"54.7"	"6.95"	"927.11"	"9.38"	"2"	"2"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01603"	"5529"	"ENSG00000154001"	"PPP2R5E"	"A4FU37; B7ZAW5; B7ZKK8; B7ZKK9; hsa:5529; J3KQN6; Q16537; Q52LW4"	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Negative regulation of MAPK pathway; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Platelet sensitization by LDL; CTLA4 inhibitory signaling"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome; DNA damage response (only ATM dependent)"	"28"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX63"	"MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1"	"0.000"	""	"12"	"3"	"5"	"3"	"227"	"26.1"	"8.28"	"757.45"	"9.37"	"2"	"3"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf05300"	"54927"	"ENSG00000106554"	"CHCHD3"	"hsa:54927; Q9NX63"	"Mitochondrial protein import; Cristae formation"	""	"2"	"0"	"38.2"	"29.4"	"54.8"	"38.3"	"39.7"	"49.7"	"112.0"	"1.4"	"1335.9"	"1359.2"	"2651.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43414"	"ERI1 exoribonuclease 3 OS=Homo sapiens OX=9606 GN=ERI3 PE=1 SV=2"	"0.000"	""	"4"	"1"	"4"	"1"	"337"	"37.2"	"8.07"	"729.86"	"9.36"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00929"	"79033"	"ENSG00000117419"	"ERI3"	"B1AK98; hsa:79033; O43414; Q5T2T7; Q5T2T9; Q5TG35; Q9BQA0; Q9UEB4"	""	""	"0"	"0"	"24.0"	"16.6"	"24.5"	"17.8"	"23.4"	"16.2"	"36.8"	"3.1"	"560.7"	"560.6"	"1441.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92522"	"Histone H1.10 OS=Homo sapiens OX=9606 GN=H1-10 PE=1 SV=1"	"0.000"	""	"15"	"3"	"5"	"3"	"213"	"22.5"	"10.76"	"752.28"	"9.35"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"8971"	"ENSG00000184897"	"H1-10"	"hsa:8971; Q92522"	""	""	"0"	"0"	"39.1"	"35.0"	"34.1"	"38.6"	"37.4"	"41.0"	"151.2"	"0.3"	"881.3"	"986.6"	"1586.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3B7T1"	"Erythroid differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDRF1 PE=1 SV=1"	"0.000"	""	"2"	"3"	"7"	"3"	"1238"	"138.4"	"6.33"	"755.66"	"9.35"	"2"	"3"	"other biological processes"	"nucleus"	""	""	"26098"	"ENSG00000107938"	"EDRF1"	"B2RC65; hsa:26098; Q3B7T1; Q3KR40; Q4G190; Q5VZQ4; Q8IZ74; Q9Y3W4"	""	""	"0"	"0"	"42.8"	"31.6"	"48.5"	"42.7"	"38.7"	"36.9"	"56.7"	"0.0"	"652.8"	"704.2"	"1344.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N442"	"Translation factor GUF1, mitochondrial OS=Homo sapiens OX=9606 GN=GUF1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"669"	"74.3"	"8.59"	"826.19"	"9.34"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"translation activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf06421"	"60558"	"ENSG00000151806"	"GUF1"	"hsa:60558; Q5XKM8; Q8N442; Q9H710; Q9H8U4"	""	""	"0"	"0"	"22.2"	"13.5"	"27.0"	"23.9"	"25.1"	"20.5"	"33.2"	"0.1"	"367.7"	"458.3"	"803.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11233"	"Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1"	"0.000"	""	"11"	"2"	"6"	"2"	"206"	"23.6"	"7.11"	"743.79"	"9.33"	"1"	"2"	"cell cycle OR cell proliferation;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00071"	"5898"	"ENSG00000006451"	"RALA"	"A4D1W3; hsa:5898; P11233"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; p38MAPK events"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"8"	"0"	"74.8"	"61.7"	"88.3"	"81.9"	"81.6"	"84.0"	"142.3"	"0.0"	"1762.4"	"1783.8"	"2936.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3Y2"	"Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2"	"0.000"	""	"13"	"3"	"5"	"3"	"248"	"26.4"	"12.23"	"1022.19"	"9.32"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf13865"	"26097"	"ENSG00000160679"	"CHTOP"	"D3DV55; hsa:26097; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4; Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0; Q9Y3Y2"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	""	"3"	"0"	"131.5"	"115.5"	"134.9"	"122.5"	"129.8"	"131.6"	"373.7"	"2.2"	"1029.7"	"912.9"	"1822.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9GZN1"	"Actin-related protein 6 OS=Homo sapiens OX=9606 GN=ACTR6 PE=1 SV=1"	""	""	"9"	"2"	"2"	"2"	"396"	"45.8"	"5.03"	""	"9.32"	""	"2"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00022"	"64431"	"ENSG00000075089"	"ACTR6"	"B3KW37; B4DLG9; hsa:64431; Q53GH2; Q9BY39; Q9GZN1; Q9H8H6"	""	""	"0"	"0"	"10.0"	"11.5"	"24.0"	"14.2"	"21.7"	"19.1"	"24.1"	"1.1"	"255.5"	"293.9"	"541.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13330"	"Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"715"	"80.7"	"9.26"	"995.72"	"9.31"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"9112"	"ENSG00000182979"	"MTA1"	"A5PLK4; hsa:9112; Q13330; Q86SW2; Q8NFI8; Q96GI8"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of transcription factors"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; TAR syndrome"	"8"	"0"	"26.4"	"12.7"	"21.9"	"15.3"	"22.5"	"20.1"	"31.9"	"1.5"	"270.7"	"240.3"	"563.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NXE4"	"Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3"	""	""	"3"	"1"	"2"	"1"	"866"	"97.7"	"8.27"	""	"9.30"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf14724"	"55627"	"ENSG00000136699"	"SMPD4"	"B1PBA3; B4DM23; B4DQ31; B4DRB8; B4DWK7; B4E0L6; E7ESA2; E9PCE6; hsa:55627; Q6FI76; Q6P1P7; Q6ZT43; Q9H0M2; Q9NW20; Q9NWL2; Q9NXE4; Q9P2C9"	"Glycosphingolipid metabolism"	""	"1"	"0"	"0.0"	"0.0"	"4.1"	"2.3"	"2.5"	"2.6"	"6.5"	"0.0"	"40.6"	"41.7"	"79.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12792"	"Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3"	"0.000"	""	"11"	"4"	"6"	"4"	"350"	"40.3"	"6.96"	"691.04"	"9.27"	"2"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"5756"	"ENSG00000151239"	"TWF1"	"A8K5A8; B3KXS6; B4DLX9; hsa:5756; Q12792; Q59G07; Q5U0B1; Q6FHJ1; Q6FHL6; Q6NUK9; Q86XL6; Q8TCD3"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOBTB2 GTPase cycle"	""	"3"	"0"	"23.7"	"18.8"	"38.7"	"36.7"	"45.1"	"28.6"	"51.8"	"0.0"	"1317.6"	"1368.0"	"2838.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4M9"	"EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"2"	"534"	"60.6"	"6.83"	"708.77"	"9.26"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"10938"	"ENSG00000110047"	"EHD1"	"hsa:10938; O14611; Q2M3Q4; Q9H4M9; Q9UNR3"	"Factors involved in megakaryocyte development and platelet production"	"Insulin signaling"	"2"	"0"	"9.1"	"6.7"	"16.7"	"10.9"	"15.5"	"11.0"	"26.7"	"8.6"	"257.0"	"242.5"	"523.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UX04"	"Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"472"	"53.8"	"5.80"	"779.11"	"9.25"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00160"	"10283"	"ENSG00000153015"	"CWC27"	"hsa:10283; O60529; O60530; Q6UX04; Q96EM3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"56.3"	"49.9"	"58.2"	"65.3"	"61.7"	"65.1"	"96.4"	"1.9"	"303.7"	"274.7"	"495.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZN8"	"UPF0687 protein C20orf27 OS=Homo sapiens OX=9606 GN=C20orf27 PE=1 SV=3"	"0.000"	""	"20"	"2"	"3"	"2"	"174"	"19.3"	"6.84"	"385.79"	"9.23"	"1"	"2"	"other metabolic processes;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf15006"	"54976"	"ENSG00000101220"	"ADISSP"	"A8K4J0; D3DVX8; hsa:54976; Q5JX81; Q9GZN8; Q9NWX3"	""	""	"0"	"0"	"7.0"	"7.0"	"14.8"	"16.4"	"20.1"	"18.0"	"27.6"	"6.0"	"418.7"	"415.3"	"834.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09417"	"Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR PE=1 SV=2"	"0.000"	""	"11"	"2"	"3"	"2"	"244"	"25.8"	"7.37"	"502.91"	"9.22"	"1"	"2"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00106"	"5860"	"ENSG00000151552"	"QDPR"	"A8K158; B3KW71; hsa:5860; P09417; Q53F52; Q9H3M5"	"Phenylalanine metabolism"	""	"1"	"0"	"5.7"	"4.4"	"6.4"	"4.8"	"8.6"	"11.0"	"22.7"	"4.0"	"372.6"	"360.7"	"897.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14155"	"Rho guanine nucleotide exchange factor 7 OS=Homo sapiens OX=9606 GN=ARHGEF7 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"803"	"90.0"	"7.09"	"832.60"	"9.20"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00621, Pf07653, Pf16614, Pf16615"	"8874"	"ENSG00000102606"	"ARHGEF7"	"B1ALK6; B1ALK8; hsa:8874; Q14155; Q3LIA4; Q5W9H0; Q6P9G3; Q6PII2; Q86W63; Q8N3M1"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOJ GTPase cycle; Ephrin signaling; RHOQ GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; EGFR downregulation"	"Integrin-mediated cell adhesion; CAMKK2 pathway; Regulation of actin cytoskeleton"	"14"	"0"	"46.5"	"20.5"	"50.0"	"50.2"	"40.5"	"27.8"	"60.2"	"1.2"	"399.3"	"417.5"	"881.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75334"	"Liprin-alpha-2 OS=Homo sapiens OX=9606 GN=PPFIA2 PE=1 SV=2"	"0.000"	""	"4"	"4"	"6"	"1"	"1257"	"143.2"	"6.11"	"1217.11"	"9.20"	"3"	"3"	"cell adhesion;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	""	"Pf00536, Pf07647"	"8499"	"ENSG00000139220"	"PPFIA2"	"B3KVT5; B3KXA0; B7Z2A6; B7Z3U9; B7Z663; B7ZKZ5; E7ERB8; E7ETG6; F8VP68; hsa:8499; O75334; Q2M3G8"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	""	"6"	"1"	"49.1"	"39.5"	"41.6"	"44.1"	"46.5"	"41.8"	"91.1"	"0.0"	"436.7"	"366.0"	"927.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZT3"	"SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1"	"0.000"	""	"20"	"2"	"3"	"2"	"109"	"12.3"	"10.24"	"467.85"	"9.20"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	""	"Pf00076"	"81892"	"ENSG00000119705"	"SLIRP"	"hsa:81892; J3KMY7; Q9GZT3"	""	""	"0"	"0"	"49.8"	"45.0"	"58.9"	"50.3"	"50.0"	"39.1"	"115.5"	"0.0"	"699.3"	"754.5"	"1729.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVR2"	"Integrator complex subunit 10 OS=Homo sapiens OX=9606 GN=INTS10 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"710"	"82.2"	"7.44"	"725.91"	"9.19"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	""	"55174"	"ENSG00000104613"	"INTS10"	"hsa:55174; Q6IA93; Q7L538; Q7L8C8; Q9H3W8; Q9NVR2"	"RNA polymerase II transcribes snRNA genes"	"1p36 copy number variation syndrome"	"2"	"0"	"89.4"	"70.7"	"121.5"	"100.3"	"110.6"	"61.0"	"153.5"	"0.0"	"1234.6"	"1359.6"	"2925.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61764"	"Syntaxin-binding protein 1 OS=Homo sapiens OX=9606 GN=STXBP1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"594"	"67.5"	"6.96"	"1150.80"	"9.16"	"3"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00995"	"6812"	"ENSG00000136854"	"STXBP1"	"B1AM97; hsa:6812; P61764; Q28208; Q62759; Q64320; Q68CM6; Q96TG8"	"Regulation of insulin secretion; Neurexins and neuroligins"	"Synaptic vesicle pathway; Rett syndrome causing genes; EGF/EGFR signaling pathway; Insulin signaling; 15q11q13 copy number variation"	"7"	"0"	"0.0"	"2.5"	"3.7"	"2.3"	"0.0"	"5.9"	"8.0"	"1.4"	"87.5"	"86.2"	"140.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00232"	"26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3"	"0.000"	""	"7"	"3"	"6"	"3"	"456"	"52.9"	"7.65"	"871.76"	"9.16"	"3"	"3"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf18098"	"5718"	"ENSG00000197170"	"PSMD12"	"A6NP15; hsa:5718; O00232; Q53HA2; Q6P053"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"39.0"	"23.1"	"54.1"	"42.1"	"54.2"	"42.5"	"83.3"	"9.0"	"743.3"	"747.6"	"1817.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYU8"	"Calcium uptake protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=MICU2 PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"434"	"49.6"	"9.09"	"751.09"	"9.15"	"2"	"2"	"transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf13833"	"221154"	"ENSG00000165487"	"MICU2"	"hsa:221154; Q8IYU8; Q8N0T6; Q8NAX8"	"Processing of SMDT1"	""	"2"	"0"	"8.9"	"4.7"	"14.0"	"10.9"	"16.5"	"6.9"	"13.1"	"0.6"	"328.7"	"334.4"	"728.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXS6"	"Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"441"	"49.4"	"9.91"	"878.87"	"9.13"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf16006"	"51203"	"ENSG00000137804"	"NUSAP1"	"B4DDF1; E7ERR5; hsa:51203; J3KN21; Q53GW2; Q8TBT4; Q96E58; Q96FJ1; Q9BXS6; Q9GZM9; Q9NZ85; Q9UI70"	""	""	"0"	"0"	"56.6"	"47.0"	"46.5"	"49.8"	"54.2"	"54.8"	"91.8"	"0.0"	"733.8"	"741.7"	"1431.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAT6"	"Nuclear protein localization protein 4 homolog OS=Homo sapiens OX=9606 GN=NPLOC4 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"2"	"608"	"68.1"	"6.38"	"935.96"	"9.10"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf05020, Pf05021, Pf11543"	"55666"	"ENSG00000182446"	"NPLOC4"	"hsa:55666; Q8N3J1; Q8TAT6; Q9H8V2; Q9H964; Q9NWR5; Q9P229"	"Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	""	"3"	"0"	"57.6"	"54.6"	"59.5"	"65.6"	"62.1"	"51.1"	"108.2"	"9.0"	"657.0"	"621.9"	"1257.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35249"	"Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2"	"0.000"	""	"11"	"4"	"6"	"4"	"363"	"39.7"	"8.02"	"960.44"	"9.09"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5984"	"ENSG00000163918"	"RFC4"	"B4DM41; D3DNV2; hsa:5984; P35249; Q6FHX7"	"Activation of ATR in response to replication stress; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"28"	"0"	"60.1"	"48.8"	"55.4"	"55.6"	"60.2"	"60.8"	"106.5"	"1.1"	"907.4"	"922.4"	"1918.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VN1"	"Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"386"	"43.8"	"7.20"	"694.80"	"9.09"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf04157, Pf11605"	"51028"	"ENSG00000136100"	"VPS36"	"A8K125; hsa:51028; Q3ZCV7; Q5H9S1; Q5VXB6; Q86VN1; Q9H8Z5; Q9Y3E3"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"Network map of SARS-CoV-2 signaling pathway"	"3"	"0"	"20.0"	"18.3"	"33.5"	"30.8"	"28.8"	"49.2"	"92.5"	"2.3"	"977.1"	"956.2"	"1766.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6ZNB6"	"NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2"	""	""	"4"	"3"	"3"	"3"	"911"	"101.3"	"8.41"	""	"9.05"	""	"3"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01422"	"152518"	"ENSG00000170448"	"NFXL1"	"B1Q2K1; hsa:152518; Q6ZNB6; Q86VG1; Q8WVH1"	""	""	"0"	"0"	"34.3"	"30.3"	"32.8"	"41.5"	"34.4"	"26.9"	"73.2"	"2.2"	"312.0"	"312.0"	"542.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2L5"	"Trafficking protein particle complex subunit 8 OS=Homo sapiens OX=9606 GN=TRAPPC8 PE=1 SV=2"	""	""	"3"	"2"	"2"	"2"	"1435"	"160.9"	"6.87"	""	"9.04"	""	"2"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	""	"Pf12739"	"22878"	"ENSG00000153339"	"TRAPPC8"	"A0JP15; B3KME5; hsa:22878; Q9H0L2; Q9Y2L5"	"RAB GEFs exchange GTP for GDP on RABs"	""	"1"	"0"	"7.8"	"3.4"	"9.4"	"8.0"	"9.1"	"4.6"	"8.6"	"0.0"	"306.0"	"243.2"	"567.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NB3"	"Zinc finger protein 830 OS=Homo sapiens OX=9606 GN=ZNF830 PE=1 SV=2"	"0.000"	""	"9"	"2"	"3"	"2"	"372"	"42.0"	"5.31"	"359.60"	"9.04"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"91603"	"ENSG00000198783"	"ZNF830"	"hsa:91603; Q96F60; Q96GZ5; Q96NB3; Q9BU38"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"17q12 copy number variation syndrome"	"6"	"0"	"47.6"	"34.2"	"47.0"	"41.4"	"48.1"	"30.7"	"112.4"	"0.4"	"439.1"	"443.8"	"902.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2Z2"	"Elongation factor-like GTPase 1 OS=Homo sapiens OX=9606 GN=EFL1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"1120"	"125.4"	"5.91"	"306.54"	"9.03"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf14492"	"79631"	"ENSG00000140598"	"EFL1"	"A6NKY5; B7Z6I0; hsa:79631; Q7Z2Z2; Q9H8Z6"	""	"Genetic causes of porto-sinusoidal vascular disease"	"1"	"0"	"0.0"	"0.0"	"6.6"	"5.3"	"0.0"	"4.6"	"4.2"	"2.8"	"201.1"	"225.1"	"467.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05386"	"60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1"	"0.000"	""	"34"	"3"	"7"	"2"	"114"	"11.5"	"4.32"	"1472.07"	"9.03"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00428"	"6176"	"ENSG00000137818"	"RPLP1"	"A6NIB2; hsa:6176; P05386"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"50.1"	"39.7"	"77.0"	"73.7"	"76.6"	"49.2"	"364.2"	"10.0"	"2292.9"	"2136.0"	"3871.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CZ6"	"HAUS augmin-like complex subunit 3 OS=Homo sapiens OX=9606 GN=HAUS3 PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"3"	"603"	"69.6"	"5.55"	"810.44"	"9.03"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	"Pf14932"	"79441"	"ENSG00000214367"	"HAUS3"	"B4DF64; hsa:79441; O43606; Q68CZ6; Q8TAZ5; Q9BTJ9"	"Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"14.9"	"15.5"	"16.4"	"20.9"	"10.8"	"15.1"	"30.0"	"0.9"	"140.8"	"137.1"	"255.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P58107"	"Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"1"	"5088"	"555.3"	"5.62"	"1062.11"	"9.03"	"2"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00681"	"83481"	"ENSG00000261150"	"EPPK1"	"A0A087X1U6; hsa:83481; P58107; Q76E58; Q9NSU9"	""	""	"0"	"0"	"5.2"	"7.2"	"4.8"	"6.4"	"4.4"	"6.5"	"11.3"	"0.0"	"50.3"	"53.9"	"90.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14320"	"Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2"	"0.000"	""	"8"	"3"	"5"	"3"	"339"	"40.2"	"6.83"	"836.69"	"9.02"	"1"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf04921"	"9130"	"ENSG00000071859"	"FAM50A"	"A8KAQ4; B2R997; hsa:9130; Q14320; Q5HY37; Q6PJH5"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"75.9"	"75.5"	"100.5"	"87.9"	"87.7"	"94.1"	"129.4"	"2.1"	"1596.5"	"1560.3"	"3103.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12979"	"Active breakpoint cluster region-related protein OS=Homo sapiens OX=9606 GN=ABR PE=1 SV=2"	"0.000"	""	"4"	"3"	"4"	"3"	"859"	"97.5"	"6.55"	"598.17"	"9.02"	"2"	"2"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00168, Pf00169, Pf00620, Pf00621"	"29"	"ENSG00000159842; ENSG00000276016; ENSG00000278741"	"ABR"	"B3KW89; B7Z6H7; D3DTH3; D3DTH4; F5H3S2; F5H8B3; hsa:29; Q12979; Q13693; Q13694"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle"	""	"9"	"0"	"2.9"	"0.0"	"4.9"	"4.2"	"4.8"	"6.0"	"13.4"	"4.4"	"303.2"	"295.8"	"510.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZR2"	"RNA exonuclease 4 OS=Homo sapiens OX=9606 GN=REXO4 PE=1 SV=2"	"0.000"	""	"8"	"3"	"5"	"3"	"422"	"46.6"	"9.77"	"600.48"	"9.01"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00929"	"57109"	"ENSG00000148300; ENSG00000280706"	"REXO4"	"B2RAT2; hsa:57109; Q5T8S4; Q5T8S5; Q5T8S6; Q9GZR2; Q9GZW3"	""	""	"0"	"0"	"72.1"	"62.1"	"72.3"	"65.6"	"66.6"	"71.6"	"156.1"	"0.5"	"1230.1"	"1371.9"	"2390.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16762"	"Thiosulfate sulfurtransferase OS=Homo sapiens OX=9606 GN=TST PE=1 SV=4"	"0.000"	""	"10"	"2"	"3"	"2"	"297"	"33.4"	"7.25"	"470.79"	"9.00"	"1"	"2"	"other metabolic processes;transport;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00581"	"7263"	"ENSG00000128311"	"TST"	"B3KRM1; hsa:7263; Q16762; Q6IB06"	"Sulfide oxidation to sulfate"	""	"2"	"0"	"17.9"	"12.6"	"19.8"	"17.9"	"17.5"	"17.5"	"28.7"	"2.3"	"330.0"	"355.3"	"967.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06746"	"DNA polymerase beta OS=Homo sapiens OX=9606 GN=POLB PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"335"	"38.2"	"8.95"	"922.99"	"8.98"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf10391, Pf14716, Pf14791, Pf14792"	"5423"	"ENSG00000070501"	"POLB"	"B2RC78; hsa:5423; P06746; Q3KP48; Q6FI34"	"Ub-specific processing proteases; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"Male infertility; Base excision repair; DNA repair pathways, full network"	"10"	"0"	"10.9"	"7.0"	"14.9"	"12.1"	"15.3"	"18.1"	"22.3"	"0.0"	"252.9"	"239.7"	"426.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y295"	"Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"367"	"40.5"	"8.90"	"1088.13"	"8.95"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"4733"	"ENSG00000185721"	"DRG1"	"B2RDS8; hsa:4733; Q6FGP8; Q8WW69; Q9UGF2; Q9Y295"	""	""	"0"	"0"	"41.1"	"35.5"	"52.5"	"43.0"	"47.6"	"49.2"	"117.3"	"3.4"	"546.1"	"565.7"	"1293.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55145"	"Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3"	"0.000"	""	"14"	"4"	"5"	"4"	"182"	"20.7"	"8.69"	"643.52"	"8.95"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf10208, Pf20145"	"7873"	"ENSG00000145050"	"MANF"	"hsa:7873; P55145; Q14CX4; Q86U67; Q96IS4"	"Platelet degranulation"	"Orexin receptor pathway"	"2"	"0"	"125.5"	"100.3"	"147.0"	"112.1"	"113.2"	"120.9"	"426.4"	"13.2"	"3320.5"	"3030.8"	"5542.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKL0"	"REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"485"	"53.3"	"7.03"	"1027.90"	"8.93"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"23186"	"ENSG00000089902"	"RCOR1"	"hsa:23186; J3KN32; Q15044; Q6P2I9; Q86VG5; Q9UKL0"	"Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; Potential therapeutics for SARS; HDACs deacetylate histones"	""	"4"	"0"	"16.9"	"10.4"	"11.9"	"14.2"	"18.0"	"14.9"	"36.2"	"3.7"	"374.1"	"353.8"	"917.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEE9"	"Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1"	"0.000"	""	"14"	"3"	"4"	"3"	"299"	"33.6"	"4.81"	"906.75"	"8.92"	"2"	"2"	"cell adhesion;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf07572"	"10428"	"ENSG00000153774"	"CFDP1"	"hsa:10428; O00393; O00404; Q9UEE9; Q9UEF0; Q9UEF1; Q9UEF8"	""	""	"0"	"0"	"144.2"	"101.9"	"131.1"	"123.3"	"112.1"	"122.7"	"170.4"	"0.5"	"505.7"	"477.9"	"907.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5T4S7"	"E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1"	""	""	"0"	"1"	"2"	"1"	"5183"	"573.5"	"6.04"	""	"8.92"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02207, Pf13764, Pf19423"	"23352"	"ENSG00000127481"	"UBR4"	"A8MPT2; A8MQ33; A8MQB1; hsa:23352; O60646; O75050; Q4QRK5; Q5T4S7; Q5T4S8; Q5T4S9; Q5TBN8; Q5TBP2; Q6DKH8; Q6P4A4; Q7L8P7; Q8IXJ4; Q8TDN5; Q8WV67; Q9HA46; Q9P2N9; Q9UG82"	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	""	"2"	"0"	"6.5"	"6.2"	"11.9"	"8.2"	"10.0"	"5.0"	"7.0"	"0.0"	"42.6"	"41.6"	"93.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13131"	"5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4"	"0.000"	""	"6"	"2"	"3"	"2"	"559"	"64.0"	"8.12"	"452.04"	"8.89"	"1"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf16579"	"5562"	"ENSG00000132356"	"PRKAA1"	"A8MTQ6; B2R7E1; hsa:5562; O00286; Q13131; Q5D0E1; Q86VS1; Q9UNQ4"	"Activation of AMPK downstream of NMDARs; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Thyroxine (thyroid hormone) production; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; mir-124 predicted interactions with cell cycle and differentiation ; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin and adiponectin; Lipid metabolism pathway; PI3K-Akt signaling pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; IL-18 signaling pathway; Insulin signaling; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Pleural mesothelioma; Disturbed pathways in Duchenne Muscular Dystrophy"	"35"	"0"	"4.4"	"6.0"	"6.5"	"4.5"	"7.1"	"2.7"	"7.8"	"0.7"	"252.7"	"264.8"	"546.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53618"	"Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"953"	"107.1"	"6.05"	"656.67"	"8.85"	"1"	"2"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01602, Pf07718, Pf14806"	"1315"	"ENSG00000129083"	"COPB1"	"D3DQX0; hsa:1315; P53618; Q6GTT7; Q9NTK2; Q9UNW7"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Neutrophil degranulation"	""	"3"	"0"	"26.3"	"18.6"	"19.3"	"18.4"	"21.7"	"13.0"	"16.7"	"4.3"	"121.6"	"107.8"	"279.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60701"	"UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1"	"0.000"	""	"10"	"4"	"6"	"4"	"494"	"55.0"	"7.12"	"901.33"	"8.84"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf00984, Pf03720, Pf03721"	"7358"	"ENSG00000109814"	"UGDH"	"B3KUU2; B4DN25; hsa:7358; O60589; O60701"	"Formation of the active cofactor, UDP-glucuronate"	"UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"3"	"0"	"54.6"	"40.0"	"59.7"	"60.0"	"59.6"	"62.1"	"93.7"	"0.0"	"1199.0"	"1230.2"	"2065.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06787"	"Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"2"	"632"	"71.1"	"7.42"	"850.68"	"8.81"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16098, Pf17904, Pf18336"	"2332"	"ENSG00000102081"	"FMR1"	"A6NNH4; D3DWT0; D3DWT1; D3DWT2; G8JL90; hsa:2332; Q06787; Q16578; Q5PQZ6; Q99054"	""	"Ovarian infertility; Serotonin and anxiety; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; Primary ovarian insufficiency"	"7"	"1"	"112.1"	"82.2"	"128.3"	"123.5"	"98.7"	"133.0"	"330.0"	"1.3"	"1399.5"	"1327.2"	"2581.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75592"	"E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4"	"0.000"	""	"1"	"3"	"5"	"3"	"4678"	"513.3"	"7.02"	"650.19"	"8.80"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf03256, Pf08005, Pf08239, Pf13540, Pf13639"	"23077"	"ENSG00000005810"	"MYCBP2"	"A6NJC6; hsa:23077; O75592; Q5JSX8; Q5VZN6; Q6PIB6; Q9UQ11; Q9Y6E4"	""	"3q29 copy number variation syndrome"	"1"	"0"	"37.2"	"30.1"	"31.8"	"34.0"	"41.2"	"38.9"	"66.1"	"0.0"	"637.7"	"675.4"	"1034.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5M775"	"Cytospin-B OS=Homo sapiens OX=9606 GN=SPECC1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"1068"	"118.5"	"6.70"	"905.32"	"8.80"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00307"	"92521"	"ENSG00000128487"	"SPECC1"	"B4DHH0; B7WNS8; hsa:92521; Q5IBP1; Q5IBP2; Q5IBP3; Q5IBP4; Q5M772; Q5M773; Q5M774; Q5M775; Q86XT8; Q8N4U4; Q8WU84; Q9HCQ3"	""	""	"0"	"0"	"45.2"	"31.2"	"38.5"	"39.1"	"41.0"	"53.3"	"98.6"	"1.6"	"364.6"	"388.6"	"743.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30085"	"UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3"	"0.000"	""	"18"	"3"	"6"	"3"	"196"	"22.2"	"5.57"	"861.07"	"8.80"	"3"	"3"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"51727"	"ENSG00000162368"	"CMPK1"	"B2R6S5; B4DPU7; E9PGI8; hsa:51727; P30085; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism"	"2"	"0"	"32.6"	"23.1"	"37.2"	"33.2"	"31.5"	"28.8"	"54.4"	"3.5"	"311.2"	"352.3"	"1047.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P01116"	"GTPase KRas OS=Homo sapiens OX=9606 GN=KRAS PE=1 SV=1"	"0.000"	""	"20"	"3"	"5"	"3"	"189"	"21.6"	"6.77"	"828.53"	"8.76"	"2"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"3845"	"ENSG00000133703"	"KRAS"	"A8K8Z5; B0LPF9; hsa:3845; P01116; P01118; Q96D10"	"Signaling by CSF3 (G-CSF); Signaling by CSF1 (M-CSF) in myeloid cells; RAS processing; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAS GAP mutants; Signaling by RAS GTPase mutants; RUNX3 regulates p14-ARF"	"IL-5 signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; RalA downstream regulated genes; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; RAC1/PAK1/p38/MMP2 pathway; G protein signaling pathways; BDNF-TrkB signaling; MAPK signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Thermogenesis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Synaptic signaling pathways associated with autism spectrum disorder; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; Kisspeptin/kisspeptin receptor system in the ovary; MAPK pathway in congenital thyroid cancer; Regulation of actin cytoskeleton; Alzheimer's disease; Autophagy in pancreatic ductal adenocarcinoma; JAK-STAT signaling in the regulation of Beta-cells; ErbB signaling pathway; DNA damage response (only ATM dependent); Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"57"	"0"	"21.4"	"26.3"	"33.3"	"29.9"	"33.3"	"40.4"	"89.4"	"2.8"	"475.6"	"516.4"	"913.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKE5"	"TRAF2 and NCK-interacting protein kinase OS=Homo sapiens OX=9606 GN=TNIK PE=1 SV=1"	"0.000"	""	"3"	"4"	"5"	"2"	"1360"	"154.8"	"7.17"	"645.45"	"8.76"	"2"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"23043"	"ENSG00000154310"	"TNIK"	"A7E2A3; A8K4U1; D3DNQ6; hsa:23043; O60298; Q8WUY7; Q9UKD8; Q9UKD9; Q9UKE0; Q9UKE1; Q9UKE2; Q9UKE3; Q9UKE4; Q9UKE5"	"Oxidative Stress Induced Senescence"	"Hippo-YAP signaling; Pleural mesothelioma"	"3"	"0"	"26.9"	"17.6"	"25.7"	"22.9"	"17.6"	"22.5"	"46.0"	"2.0"	"301.4"	"314.9"	"561.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35658"	"Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2"	"0.000"	""	"2"	"3"	"4"	"3"	"2090"	"213.5"	"7.47"	"569.09"	"8.75"	"2"	"2"	"cell cycle OR cell proliferation;other metabolic processes;transport;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf18617"	"8021"	"ENSG00000126883"	"NUP214"	"A6NFQ0; hsa:8021; P35658; Q15010; Q3KQZ0; Q5JUP7; Q75R47; Q86XD3"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HuR (ELAVL1) binds and stabilizes mRNA"	""	"29"	"0"	"95.1"	"73.2"	"99.7"	"107.6"	"91.0"	"96.9"	"188.8"	"7.9"	"1180.4"	"1113.9"	"2050.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46087"	"Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"812"	"89.2"	"9.23"	"590.81"	"8.74"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01189, Pf08062, Pf17125"	"4839"	"ENSG00000111641"	"NOP2"	"A1A4Z3; B3KPD6; hsa:4839; P46087; Q05BA7; Q0P5S5; Q3KQS4; Q58F30"	"rRNA modification in the nucleus and cytosol; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"Imatinib and chronic myeloid leukemia"	"3"	"0"	"72.1"	"60.7"	"77.6"	"74.3"	"68.6"	"76.0"	"186.2"	"0.0"	"788.8"	"788.7"	"1740.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z6Z7"	"E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"4374"	"481.6"	"5.22"	"245.13"	"8.73"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00627, Pf00632, Pf02825, Pf06012, Pf06025, Pf14377"	"10075"	"ENSG00000086758"	"HUWE1"	"hsa:10075; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q7Z6Z7; Q8NG67; Q9BUI0; Q9HCJ4; Q9NSL6; Q9P0A9"	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T280"	"Putative methyltransferase C9orf114 OS=Homo sapiens OX=9606 GN=SPOUT1 PE=1 SV=3"	"0.000"	""	"10"	"2"	"3"	"2"	"376"	"42.0"	"7.43"	"367.83"	"8.72"	"1"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02598"	"51490"	"ENSG00000198917"	"SPOUT1"	"hsa:51490; Q0D2P6; Q5T280; Q6P469; Q6PGP9; Q6PIJ1; Q6PJV9"	""	""	"0"	"0"	"20.4"	"10.2"	"16.4"	"15.7"	"15.1"	"17.9"	"39.1"	"3.1"	"442.1"	"452.6"	"825.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PY5"	"Formin-like protein 2 OS=Homo sapiens OX=9606 GN=FMNL2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"6"	"2"	"1086"	"123.2"	"7.40"	"1035.30"	"8.70"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"114793"	"ENSG00000157827"	"FMNL2"	"B2RZH5; hsa:114793; Q14CC9; Q4ZG52; Q8N3E0; Q96PY5"	"RHOC GTPase cycle; CDC42 GTPase cycle; RHO GTPases Activate Formins"	"Epithelial to mesenchymal transition in colorectal cancer"	"4"	"0"	"34.3"	"29.5"	"31.5"	"28.0"	"34.3"	"32.9"	"81.1"	"4.0"	"685.3"	"661.6"	"944.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95825"	"Quinone oxidoreductase-like protein 1 OS=Homo sapiens OX=9606 GN=CRYZL1 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"349"	"38.7"	"5.78"	"1031.88"	"8.70"	"2"	"2"	"other metabolic processes"	""	"other molecular function"	""	"9946"	"ENSG00000205758"	"CRYZL1"	"B2RDX1; B3KQ77; hsa:9946; O95825; Q96DY0; Q9NVY7"	""	""	"0"	"0"	"4.1"	"2.2"	"5.3"	"8.5"	"6.5"	"2.9"	"17.0"	"6.1"	"255.1"	"209.9"	"419.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB9"	"Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"627"	"70.7"	"8.56"	"1046.80"	"8.65"	"3"	"3"	"transport;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf16969"	"6730"	"ENSG00000167881"	"SRP68"	"B3KUU5; B3KWY7; G3V1U4; hsa:6730; Q8NCJ4; Q8WUK2; Q9UHB9"	"SRP-dependent cotranslational protein targeting to membrane"	""	"1"	"0"	"51.8"	"35.0"	"68.6"	"49.7"	"56.9"	"50.3"	"135.2"	"0.0"	"617.1"	"616.8"	"1377.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L266"	"Isoaspartyl peptidase/L-asparaginase OS=Homo sapiens OX=9606 GN=ASRGL1 PE=1 SV=2"	"0.000"	""	"12"	"3"	"4"	"3"	"308"	"32.0"	"6.24"	"297.19"	"8.63"	"1"	"3"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01112"	"80150"	"ENSG00000162174"	"ASRGL1"	"B2R7Q0; hsa:80150; Q567Q4; Q6P1P0; Q7L266; Q8NI34; Q9H6F7"	"Phenylalanine metabolism"	""	"1"	"0"	"20.9"	"9.0"	"16.6"	"19.6"	"22.2"	"19.8"	"35.6"	"0.0"	"614.6"	"628.9"	"1405.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17980"	"26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3"	"0.000"	""	"12"	"3"	"5"	"3"	"439"	"49.2"	"5.24"	"1612.72"	"8.63"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5702"	"ENSG00000165916"	"PSMC3"	"B2R8V1; hsa:5702; P17980; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"69.6"	"65.1"	"73.5"	"63.2"	"66.0"	"57.8"	"107.3"	"6.3"	"531.0"	"461.0"	"1015.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75151"	"Lysine-specific demethylase PHF2 OS=Homo sapiens OX=9606 GN=PHF2 PE=1 SV=4"	"0.000"	""	"3"	"2"	"4"	"2"	"1096"	"120.7"	"9.17"	"812.44"	"8.63"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628, Pf02373, Pf17811"	"5253"	"ENSG00000197724"	"PHF2"	"hsa:5253; O75151; Q4VXG0; Q8N3K2; Q9Y6N4"	"HDMs demethylate histones"	""	"1"	"0"	"26.2"	"24.3"	"20.9"	"25.6"	"21.7"	"28.1"	"45.4"	"2.6"	"204.1"	"225.6"	"400.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2R7"	"Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"463"	"50.3"	"7.42"	"642.51"	"8.63"	"1"	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf08442"	"8803"	"ENSG00000136143"	"SUCLA2"	"B2RDE7; hsa:8803; O95194; Q5T9Q4; Q5T9Q6; Q9NV21; Q9NVP7; Q9P2R7"	"Citric acid cycle (TCA cycle)"	""	"1"	"0"	"14.0"	"10.8"	"13.1"	"13.7"	"19.4"	"13.5"	"23.5"	"0.0"	"399.2"	"420.0"	"1407.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IQ49"	"Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1"	"0.000"	""	"11"	"4"	"7"	"4"	"451"	"49.7"	"6.05"	"1524.53"	"8.62"	"4"	"3"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13019, Pf13297"	"163859"	"ENSG00000143751"	"SDE2"	"A8K4P3; hsa:163859; Q5TD36; Q6IQ49; Q6ZS26; Q8NAG7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"145.2"	"99.8"	"147.1"	"138.2"	"128.8"	"139.5"	"281.2"	"1.7"	"1359.3"	"1377.5"	"2332.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P1Y6"	"PHD and RING finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PHRF1 PE=1 SV=3"	"0.000"	""	"2"	"3"	"5"	"2"	"1649"	"178.6"	"8.95"	"1099.11"	"8.61"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00628, Pf13639"	"57661"	"ENSG00000070047; ENSG00000274780"	"PHRF1"	"A6H8W1; B7ZM64; B9EGP0; C9JS82; hsa:57661; Q6PJP2; Q8IVY2; Q8N2Y7; Q9BSM2; Q9P1Y6"	""	""	"0"	"0"	"76.0"	"54.3"	"58.1"	"75.0"	"68.0"	"69.2"	"158.0"	"1.8"	"544.5"	"600.9"	"1009.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62875"	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1"	"0.000"	""	"60"	"2"	"3"	"2"	"67"	"7.6"	"7.77"	"468.75"	"8.60"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01194"	"5441"	"ENSG00000177700"	"POLR2L"	"hsa:5441; P52436; P62875; Q6FHX3"	"mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"56"	"0"	"32.6"	"23.9"	"39.7"	"31.2"	"35.5"	"18.2"	"43.6"	"0.0"	"577.4"	"541.2"	"1266.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZL7"	"Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"423"	"47.7"	"5.90"	"517.99"	"8.60"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08154"	"55759"	"ENSG00000138442"	"WDR12"	"B3KPA9; hsa:55759; Q96HU0; Q9GZL7; Q9NV80; Q9NYI8"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"33.0"	"27.1"	"38.9"	"36.8"	"35.1"	"41.5"	"89.2"	"1.4"	"446.0"	"420.0"	"1037.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14697"	"Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"944"	"106.8"	"6.14"	"501.70"	"8.59"	"2"	"3"	"protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf01055, Pf13802"	"23193"	"ENSG00000089597"	"GANAB"	"A6NC20; hsa:23193; Q14697; Q8WTS9; Q9P0X0"	"Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"N-glycan biosynthesis"	"5"	"0"	"33.5"	"33.4"	"43.4"	"35.7"	"46.4"	"41.4"	"46.5"	"0.0"	"243.0"	"269.9"	"393.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30038"	"Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH4A1 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"563"	"61.7"	"8.07"	"545.58"	"8.57"	"1"	"2"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00171"	"8659"	"ENSG00000159423"	"ALDH4A1"	"A8K1Q7; B4DGE4; D2D4A3; hsa:8659; P30038; Q16882; Q53HU4; Q5JNV6; Q8IZ38; Q96IF0; Q9UDI6"	"Glyoxylate metabolism and glycine degradation; Proline catabolism"	"22q11.2 copy number variation syndrome; p53 transcriptional gene network"	"4"	"0"	"21.0"	"14.4"	"26.6"	"23.3"	"26.9"	"16.3"	"31.4"	"0.1"	"610.9"	"584.1"	"1230.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75970"	"Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"2070"	"221.5"	"5.06"	"335.88"	"8.57"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf09045, Pf16667"	"8777"	"ENSG00000107186"	"MPDZ"	"A6NLC2; B2RTS3; B7ZMI4; hsa:8777; O43798; O75970; Q4LE30; Q5CZ80; Q5JTX3; Q5JTX6; Q5JTX7; Q5JUC3; Q5JUC4; Q5VZ62; Q8N790"	""	""	"0"	"0"	"13.0"	"7.9"	"18.9"	"8.1"	"13.2"	"16.4"	"23.3"	"3.4"	"151.5"	"163.2"	"344.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08240"	"Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"638"	"69.8"	"8.95"	"667.06"	"8.56"	"1"	"2"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00448, Pf02881, Pf04086"	"6734"	"ENSG00000182934"	"SRPRA"	"A6NIB3; B2R5Z8; B4E0H3; E9PJS4; hsa:6734; P08240; Q9BVJ4"	"SRP-dependent cotranslational protein targeting to membrane; XBP1(S) activates chaperone genes"	""	"2"	"0"	"51.0"	"39.0"	"51.7"	"36.7"	"33.2"	"45.8"	"94.3"	"0.0"	"742.6"	"744.4"	"1754.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16555"	"Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"572"	"62.3"	"6.38"	"840.75"	"8.56"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf01979"	"1808"	"ENSG00000092964"	"DPYSL2"	"A8K5H2; B4DR31; D3DSS7; hsa:1808; O00424; Q16555"	"Recycling pathway of L1; CRMPs in Sema3A signaling"	"Microtubule cytoskeleton regulation; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"4"	"0"	"0.0"	"0.0"	"3.9"	"3.4"	"4.9"	"2.2"	"4.7"	"0.0"	"34.1"	"33.3"	"72.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6I9Y2"	"THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3"	"0.000"	""	"16"	"2"	"4"	"2"	"204"	"23.7"	"5.67"	"754.29"	"8.55"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05615"	"80145"	"ENSG00000163634"	"THOC7"	"hsa:80145; Q6I9Y2; Q6P1L3; Q8WUF2; Q9H5H0"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"22.0"	"12.4"	"27.3"	"22.4"	"23.5"	"24.4"	"58.1"	"2.0"	"487.7"	"476.2"	"847.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43314"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1243"	"140.3"	"8.22"	"805.83"	"8.55"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"23262"	"ENSG00000145725"	"PPIP5K2"	"A1NI53; A6NGS8; hsa:23262; O43314; Q8TB50"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"7.7"	"3.5"	"16.9"	"10.1"	"13.9"	"9.4"	"16.3"	"0.0"	"167.8"	"193.6"	"374.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13243"	"Serine/arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1"	"0.000"	""	"12"	"2"	"3"	"1"	"272"	"31.2"	"11.59"	"328.00"	"8.53"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6430"	"ENSG00000100650"	"SRSF5"	"hsa:6430; O14797; Q13243; Q16662; Q49AD6; Q6FGE0"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"mRNA processing"	"6"	"0"	"17.0"	"12.1"	"17.3"	"21.9"	"14.7"	"15.4"	"33.6"	"1.3"	"167.8"	"136.3"	"332.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC52"	"Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3"	"0.000"	""	"8"	"2"	"4"	"2"	"389"	"43.4"	"9.91"	"830.15"	"8.50"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"57332"	"ENSG00000141570"	"CBX8"	"hsa:57332; Q96H39; Q9HC52; Q9NR07"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; Regulation of PTEN gene transcription"	""	"8"	"0"	"27.3"	"32.9"	"32.5"	"27.9"	"32.6"	"30.2"	"95.7"	"0.0"	"274.3"	"271.3"	"454.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38606"	"V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"617"	"68.3"	"5.52"	"1045.13"	"8.49"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874, Pf16886"	"523"	"ENSG00000114573"	"ATP6V1A"	"B2RBR8; B7Z1R5; D3DN75; hsa:523; P38606; Q53YD9; Q96DY6; Q9UHY3"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"Proximal tubule transport"	"6"	"0"	"15.9"	"16.9"	"21.1"	"22.7"	"13.2"	"15.9"	"32.2"	"2.0"	"202.9"	"195.3"	"436.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVH1"	"DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"559"	"63.2"	"8.40"	"913.82"	"8.43"	"2"	"2"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	""	"Pf00226, Pf11875"	"55735"	"ENSG00000007923"	"DNAJC11"	"hsa:55735; Q4VWF5; Q5VZN0; Q6PK20; Q6PK70; Q8NDM2; Q96CL7; Q9NVH1"	"Cristae formation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY5"	"Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"273"	"28.8"	"8.91"	"448.36"	"8.42"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf10240"	"93343"	"ENSG00000141971"	"MVB12A"	"hsa:93343; Q96EY5; Q96I18"	"Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; HCMV Late Events"	"7q11.23 copy number variation syndrome"	"6"	"0"	"18.2"	"18.0"	"25.1"	"18.8"	"26.1"	"21.2"	"41.5"	"1.2"	"549.6"	"547.0"	"1249.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVI1"	"Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4"	"0.000"	""	"3"	"4"	"7"	"3"	"1328"	"149.2"	"6.74"	"1190.32"	"8.40"	"4"	"3"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14674, Pf14675, Pf14676, Pf14677, Pf14678, Pf14679, Pf14680"	"55215"	"ENSG00000140525"	"FANCI"	"A4ZVE4; A5YMH4; A6NJZ0; hsa:55215; Q96JN1; Q96ST0; Q9BT96; Q9NVI1"	"TP53 Regulates Transcription of DNA Repair Genes; Fanconi Anemia Pathway"	"Gastric cancer network 2; DNA repair pathways, full network; 15q11q13 copy number variation"	"5"	"0"	"14.1"	"11.7"	"18.3"	"5.7"	"10.3"	"9.5"	"36.7"	"8.5"	"509.9"	"540.4"	"931.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBS9"	"Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2"	"0.000"	""	"13"	"5"	"6"	"5"	"432"	"47.6"	"5.97"	"885.20"	"8.39"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00085"	"81567"	"ENSG00000239264"	"TXNDC5"	"B2RDM2; hsa:81567; Q5TCQ0; Q8NBS9; Q8ND33; Q8TCT2; Q9BVH9"	"Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Lysosome Vesicle Biogenesis"	"VEGFA-VEGFR2 signaling"	"4"	"0"	"366.7"	"357.1"	"335.5"	"350.4"	"330.4"	"311.8"	"521.6"	"0.0"	"1639.8"	"1564.5"	"3081.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48426"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha OS=Homo sapiens OX=9606 GN=PIP4K2A PE=1 SV=2"	"0.000"	""	"8"	"3"	"4"	"1"	"406"	"46.2"	"6.99"	"713.20"	"8.37"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf01504"	"5305"	"ENSG00000150867"	"PIP4K2A"	"B0YJ66; B4DGX2; D3DRV1; hsa:5305; P48426; P53807; Q5VUX3"	"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Synthesis of PIPs at the plasma membrane; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"Regulation of actin cytoskeleton; G13 signaling pathway"	"6"	"2"	"39.6"	"22.2"	"49.0"	"47.6"	"52.7"	"45.4"	"192.5"	"8.9"	"977.9"	"987.8"	"1632.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ0"	"PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"340"	"36.5"	"5.41"	"932.56"	"8.35"	"2"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"5074"	"ENSG00000177425"	"PAWR"	"hsa:5074; O75796; Q6FHY9; Q8N700; Q96IZ0"	""	""	"0"	"0"	"42.8"	"27.7"	"40.7"	"41.6"	"30.0"	"33.8"	"59.4"	"0.0"	"769.5"	"802.4"	"1536.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ16"	"Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4"	"0.000"	""	"3"	"3"	"5"	"1"	"869"	"97.7"	"8.35"	"657.89"	"8.35"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"26052"	"ENSG00000197959"	"DNM3"	"A9Z1Y1; hsa:26052; O14982; O95555; Q1MTM8; Q5W129; Q6P2G1; Q9H0P3; Q9H548; Q9NQ68; Q9NQN6; Q9UQ16"	"Clathrin-mediated endocytosis; Recycling pathway of L1; MHC class II antigen presentation; Retrograde neurotrophin signalling; Toll Like Receptor 4 (TLR4) Cascade"	"Synaptic vesicle pathway; Alstrom syndrome; 15q25 copy number variation"	"8"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"10.0"	"0.0"	"48.0"	"45.9"	"91.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z417"	"Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"695"	"76.1"	"8.70"	"390.06"	"8.33"	"1"	"2"	""	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf15293"	"57532"	"ENSG00000108256"	"NUFIP2"	"A1L3A6; A1L3A7; hsa:57532; Q7Z417; Q9P2M5"	""	""	"0"	"0"	"205.0"	"158.6"	"195.0"	"184.2"	"161.6"	"196.8"	"339.4"	"0.0"	"1113.2"	"1030.6"	"2029.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P49588"	"Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2"	""	""	"2"	"2"	"2"	"2"	"968"	"106.7"	"5.53"	""	"8.33"	""	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf02272, Pf07973"	"16"	"ENSG00000090861"	"AARS1"	"A6NF14; B4DR45; hsa:16; P49588; Q53GV7; Q96FA0"	"Cytosolic tRNA aminoacylation"	"IL-18 signaling pathway"	"2"	"0"	"11.6"	"5.9"	"19.9"	"13.2"	"14.5"	"11.4"	"18.5"	"0.0"	"408.0"	"464.9"	"1722.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96017"	"Serine/threonine-protein kinase Chk2 OS=Homo sapiens OX=9606 GN=CHEK2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"543"	"60.9"	"5.91"	"1074.16"	"8.33"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00498"	"11200"	"ENSG00000183765"	"CHEK2"	"A8K3Y9; B7ZBF3; B7ZBF4; B7ZBF5; hsa:11200; O96017; Q6QA03; Q6QA04; Q6QA05; Q6QA06; Q6QA07; Q6QA08; Q6QA10; Q6QA11; Q6QA12; Q6QA13; Q9HBS5; Q9HCQ8; Q9UGF0; Q9UGF1"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Regulation of TP53 Degradation; Regulation of TP53 Activity through Phosphorylation; Regulation of TP53 Activity through Methylation; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Stabilization of p53"	"miRNA regulation of DNA damage response; Cell cycle; ATM signaling in development and disease ; miRNA regulation of p53 pathway in prostate cancer; DNA damage response"	"13"	"0"	"2.5"	"3.2"	"0.0"	"4.2"	"0.0"	"3.7"	"6.8"	"1.9"	"95.9"	"93.0"	"259.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y608"	"Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"721"	"82.1"	"6.95"	"681.83"	"8.29"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	""	"other molecular function"	"Pf09738"	"9209"	"ENSG00000093167"	"LRRFIP2"	"A8K649; A8MXR0; B4DY63; hsa:9209; Q68CV3; Q9NXH5; Q9Y608"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"10.6"	"5.6"	"7.7"	"10.0"	"7.1"	"9.5"	"12.1"	"0.0"	"155.3"	"146.8"	"331.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPJ3"	"Acyl-coenzyme A thioesterase 13 OS=Homo sapiens OX=9606 GN=ACOT13 PE=1 SV=1"	"0.000"	""	"9"	"1"	"3"	"1"	"140"	"15.0"	"9.14"	"517.73"	"8.29"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf03061"	"55856"	"ENSG00000112304"	"ACOT13"	"F5H2L4; hsa:55856; O95549; Q9NPJ3"	"Mitochondrial Fatty Acid Beta-Oxidation"	""	"1"	"0"	"12.0"	"7.5"	"15.6"	"11.5"	"15.1"	"17.8"	"35.5"	"1.6"	"286.0"	"269.8"	"726.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBS4"	"DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1"	"0.000"	""	"12"	"3"	"4"	"3"	"358"	"40.5"	"6.18"	"969.09"	"8.27"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf01556"	"51726"	"ENSG00000090520"	"DNAJB11"	"hsa:51726; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6; Q9UBS4"	"XBP1(S) activates chaperone genes"	"Photodynamic therapy-induced unfolded protein response"	"2"	"0"	"150.6"	"93.0"	"162.0"	"137.2"	"166.4"	"97.5"	"109.0"	"0.2"	"696.6"	"691.1"	"1402.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00403"	"Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1"	"0.000"	""	"21"	"3"	"5"	"3"	"227"	"25.5"	"4.82"	"991.15"	"8.27"	"3"	"2"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00116, Pf02790"	"4513"	"ENSG00000198712"	"MT-CO2"	"hsa:4513; P00403; Q37526"	"Cytoprotection by HMOX1; Respiratory electron transport; TP53 Regulates Metabolic Genes"	"Electron transport chain: OXPHOS system in mitochondria; Endothelin pathways; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Neuroinflammation; Mitochondrial complex IV assembly; CCL18 signaling pathway; 5q35 copy number variation"	"11"	"0"	"18.6"	"9.0"	"22.4"	"16.3"	"17.4"	"20.2"	"29.5"	"2.4"	"378.9"	"450.2"	"905.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96B26"	"Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1"	"0.000"	""	"16"	"2"	"3"	"2"	"276"	"30.0"	"5.30"	"347.94"	"8.25"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"11340"	"ENSG00000120699"	"EXOSC8"	"hsa:11340; O43480; Q5TBA5; Q96B26"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"13.5"	"3.8"	"13.4"	"8.4"	"12.4"	"15.3"	"30.5"	"1.7"	"184.7"	"198.1"	"387.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EI5"	"Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2"	"0.000"	""	"19"	"3"	"5"	"3"	"215"	"24.6"	"5.20"	"809.79"	"8.25"	"2"	"3"	""	"nucleus"	""	"Pf04538"	"79921"	"ENSG00000133142"	"TCEAL4"	"hsa:79921; Q8WY12; Q96EI5; Q9H2H1; Q9H775"	""	""	"0"	"0"	"186.4"	"136.8"	"153.1"	"166.8"	"163.0"	"157.7"	"230.5"	"0.0"	"865.7"	"857.0"	"1418.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ24"	"Zinc finger FYVE domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZFYVE21 PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"2"	"234"	"26.5"	"8.41"	"440.12"	"8.25"	"1"	"2"	""	"other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf16696"	"79038"	"ENSG00000100711"	"ZFYVE21"	"A8K3A4; hsa:79038; Q86T05; Q96LT1; Q9BQ24"	""	""	"0"	"0"	"23.2"	"22.2"	"30.4"	"26.6"	"21.8"	"18.6"	"69.5"	"0.0"	"319.1"	"321.7"	"602.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60678"	"Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4"	"0.000"	""	"5"	"2"	"4"	"2"	"531"	"59.9"	"5.35"	"687.09"	"8.24"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf06325"	"10196"	"ENSG00000185238"	"PRMT3"	"A0A0A0MSN7; B4DUC7; hsa:10196; O60678"	"RMTs methylate histone arginines; Protein methylation"	"Nitric oxide metabolism in cystic fibrosis"	"3"	"0"	"16.8"	"17.7"	"32.1"	"20.9"	"31.1"	"21.3"	"45.0"	"3.5"	"281.9"	"313.2"	"684.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTT0"	"Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"268"	"30.7"	"3.85"	"882.10"	"8.24"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14580"	"81611"	"ENSG00000143401"	"ANP32E"	"B4E0I6; E9PEA6; hsa:81611; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9; Q9BTT0"	""	""	"0"	"0"	"29.8"	"22.1"	"35.3"	"34.3"	"39.5"	"26.2"	"51.8"	"6.3"	"482.0"	"449.3"	"822.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P1U0"	"DNA-directed RNA polymerase I subunit RPA12 OS=Homo sapiens OX=9606 GN=ZNRD1 PE=1 SV=1"	"0.000"	""	"19"	"2"	"3"	"2"	"126"	"13.9"	"5.06"	"264.07"	"8.23"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096"	"30834"	"ENSG00000066379; ENSG00000206502; ENSG00000224859; ENSG00000233795; ENSG00000235176; ENSG00000235443; ENSG00000236808; ENSG00000236949"	"POLR1H"	"hsa:30834; Q9P1U0"	"RNA Polymerase I Transcription Initiation; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"7"	"0"	"33.9"	"23.0"	"39.9"	"36.9"	"40.7"	"20.3"	"93.1"	"0.0"	"1165.0"	"1057.9"	"2032.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT09"	"Protein canopy homolog 3 OS=Homo sapiens OX=9606 GN=CNPY3 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"278"	"30.7"	"5.49"	"465.79"	"8.22"	"1"	"2"	"stress response"	"ER/Golgi"	"signal transduction activity or receptor binding"	"Pf11938"	"10695"	"ENSG00000137161"	"CNPY3"	"hsa:10695; O15412; Q0P6I2; Q8NF54; Q8WTU8; Q9BT09; Q9P0F2"	"Trafficking and processing of endosomal TLR"	""	"1"	"0"	"3.5"	"2.4"	"9.1"	"2.8"	"3.8"	"5.2"	"12.3"	"0.5"	"389.9"	"382.0"	"691.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQA1"	"Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1"	"0.000"	""	"9"	"3"	"4"	"3"	"342"	"36.7"	"5.17"	"319.27"	"8.18"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"79084"	"ENSG00000116455"	"WDR77"	"B3KMW6; B4DP38; hsa:79084; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BQA1; Q9BWY3"	"snRNP Assembly; RMTs methylate histone arginines"	""	"2"	"0"	"35.8"	"12.1"	"38.8"	"33.6"	"39.2"	"23.1"	"45.5"	"1.1"	"390.4"	"354.3"	"889.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7L2H7"	"Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1"	""	""	"8"	"2"	"2"	"2"	"374"	"42.5"	"5.63"	""	"8.16"	""	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01399, Pf18005"	"10480"	"ENSG00000149100"	"EIF3M"	"A8K7X4; B4E2Q4; hsa:10480; O60735; Q2F836; Q53HL6; Q7L2H7; Q9BXW1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	""	"6"	"0"	"14.0"	"5.7"	"18.1"	"9.8"	"15.7"	"13.6"	"29.3"	"2.5"	"193.2"	"197.1"	"844.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WJ1"	"Chromodomain-helicase-DNA-binding protein 1-like OS=Homo sapiens OX=9606 GN=CHD1L PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"897"	"100.9"	"6.90"	"275.92"	"8.16"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"9557"	"ENSG00000131778"	"CHD1L"	"A5YM64; B4DDE1; B5MDZ7; hsa:9557; Q53EZ3; Q5VXX7; Q6DD94; Q6PK83; Q86WJ1; Q86XH3; Q96HF7; Q96SP3; Q9BVJ1; Q9NVV8"	"Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"1q21.1 copy number variation syndrome; Nucleotide excision repair in xeroderma pigmentosum"	"4"	"0"	"6.3"	"7.4"	"10.5"	"7.5"	"8.2"	"6.9"	"17.8"	"0.0"	"193.0"	"173.9"	"335.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14156"	"Protein EFR3 homolog A OS=Homo sapiens OX=9606 GN=EFR3A PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"821"	"92.9"	"6.70"	"759.31"	"8.14"	"3"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	""	"23167"	"ENSG00000132294"	"EFR3A"	"A7MD19; hsa:23167; Q14156; Q2VPK2; Q63HL7; Q68DX1; Q6IQ18"	""	""	"0"	"0"	"2.5"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"3.4"	"0.0"	"30.9"	"24.0"	"52.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13861"	"cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"404"	"45.5"	"5.07"	"795.01"	"8.14"	"2"	"2"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5576"	"ENSG00000114302"	"PRKAR2A"	"hsa:5576; P13861; Q16823; Q9BUB1"	"Factors involved in megakaryocyte development and platelet production; GPER1 signaling; FCGR3A-mediated IL10 synthesis; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"20"	"0"	"11.8"	"12.5"	"17.8"	"14.4"	"18.4"	"18.4"	"33.7"	"2.5"	"230.9"	"250.8"	"614.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99848"	"Probable rRNA-processing protein EBP2 OS=Homo sapiens OX=9606 GN=EBNA1BP2 PE=1 SV=2"	"0.000"	""	"11"	"3"	"5"	"3"	"306"	"34.8"	"10.10"	"1289.81"	"8.13"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf05890"	"10969"	"ENSG00000117395"	"EBNA1BP2"	"hsa:10969; Q96A66; Q99848"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"123.6"	"126.2"	"121.4"	"106.1"	"109.3"	"107.7"	"389.7"	"3.9"	"1101.5"	"1120.7"	"1946.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17096"	"High mobility group protein HMG-I/HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3"	"0.000"	""	"36"	"4"	"5"	"4"	"107"	"11.7"	"10.32"	"560.64"	"8.11"	"2"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	""	"3159"	"ENSG00000137309"	"HMGA1"	"hsa:3159; P10910; P17096; Q5T6U9; Q9UKB0"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"Adipogenesis; Pre-implantation embryo; Male infertility; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Orexin receptor pathway"	"13"	"0"	"138.5"	"87.3"	"179.6"	"168.6"	"129.3"	"134.3"	"343.6"	"2.6"	"1230.3"	"1144.6"	"3504.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXF0"	"Serine/arginine-rich splicing factor 12 OS=Homo sapiens OX=9606 GN=SRSF12 PE=2 SV=1"	"0.000"	""	"9"	"2"	"4"	"1"	"261"	"30.5"	"11.69"	"987.09"	"8.10"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"135295"	"ENSG00000154548"	"SRSF12"	"B2RA22; hsa:135295; Q5T7K0; Q8WW25; Q8WXF0"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	""	"2"	"0"	"13.9"	"19.3"	"13.7"	"14.0"	"12.6"	"18.2"	"61.3"	"0.0"	"123.1"	"191.4"	"190.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MG7"	"Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1"	"0.000"	""	"9"	"3"	"4"	"3"	"304"	"34.3"	"9.28"	"387.30"	"8.09"	"1"	"3"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01454"	"56160"	"ENSG00000185115; ENSG00000282130"	"NSMCE3"	"hsa:56160; Q8IW16; Q8TEI6; Q96MG7; Q9H214"	"SUMOylation of DNA damage response and repair proteins"	"15q11q13 copy number variation"	"2"	"0"	"116.8"	"80.8"	"91.4"	"91.8"	"95.4"	"87.1"	"168.3"	"1.0"	"1329.4"	"1347.0"	"2526.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21127"	"Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4"	"0.000"	""	"5"	"3"	"4"	"3"	"795"	"92.6"	"5.54"	"536.81"	"8.09"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"984"	"ENSG00000248333"	"CDK11B"	"B7ZVY7; hsa:984; J3KTL7; J3QR29; J3QR44; O95265; P21127; Q12817; Q12818; Q12819; Q12820; Q12822; Q8N530; Q9NZS5; Q9UBJ0; Q9UBQ1; Q9UBR0; Q9UNY2; Q9UP57; Q9UP58; Q9UP59"	"Recruitment of mitotic centrosome proteins and complexes"	"1p36 copy number variation syndrome"	"2"	"0"	"161.4"	"142.4"	"147.1"	"161.1"	"147.3"	"105.9"	"250.6"	"1.3"	"913.9"	"893.1"	"2166.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60245"	"Protocadherin-7 OS=Homo sapiens OX=9606 GN=PCDH7 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1069"	"116.0"	"5.19"	"798.76"	"8.09"	"2"	"2"	"cell adhesion"	"plasma membrane;other membranes"	"other molecular function"	"Pf00028, Pf08266, Pf08374"	"5099"	"ENSG00000169851"	"PCDH7"	"hsa:5099; O60245; O60246; O60247; Q4W5C4"	"RHOA GTPase cycle; RHOB GTPase cycle; Platelet degranulation"	""	"3"	"0"	"12.4"	"4.9"	"9.8"	"9.4"	"13.5"	"9.9"	"21.9"	"6.2"	"574.2"	"597.6"	"1546.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95251"	"Histone acetyltransferase KAT7 OS=Homo sapiens OX=9606 GN=KAT7 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"611"	"70.6"	"8.85"	"266.47"	"8.07"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01530, Pf01853, Pf17772"	"11143"	"ENSG00000136504"	"KAT7"	"B3KN74; B4DF85; B4DFB4; B4DFE0; B4DGY4; E7ER15; G5E9K7; hsa:11143; O95251"	"HATs acetylate histones"	"Androgen receptor signaling pathway"	"2"	"0"	"3.3"	"0.0"	"8.4"	"5.9"	"2.8"	"1.8"	"9.7"	"1.5"	"68.1"	"79.5"	"162.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15678"	"Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens OX=9606 GN=PTPN14 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1187"	"135.2"	"8.31"	"957.58"	"8.06"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102, Pf00373, Pf09379, Pf09380"	"5784"	"ENSG00000152104"	"PTPN14"	"hsa:5784; Q15678; Q5VSI0"	"Interleukin-37 signaling"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"9.1"	"4.0"	"6.2"	"6.3"	"6.7"	"8.3"	"15.8"	"0.4"	"68.6"	"70.2"	"123.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51858"	"Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"240"	"26.8"	"4.73"	"416.37"	"8.06"	"1"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00855"	"3068"	"ENSG00000143321"	"HDGF"	"B3KU21; D3DVC9; hsa:3068; P51858; Q5SZ07; Q5SZ08; Q5SZ09"	"XBP1(S) activates chaperone genes"	"IL-18 signaling pathway"	"2"	"0"	"36.8"	"30.3"	"42.6"	"45.1"	"40.9"	"35.5"	"52.9"	"5.8"	"441.0"	"445.1"	"1682.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVX2"	"Notchless protein homolog 1 OS=Homo sapiens OX=9606 GN=NLE1 PE=1 SV=4"	"0.000"	""	"11"	"3"	"4"	"3"	"485"	"53.3"	"7.34"	"616.87"	"8.06"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus"	""	"Pf00400, Pf08154"	"54475"	"ENSG00000073536"	"NLE1"	"hsa:54475; O60868; Q59GJ8; Q9BU54; Q9NVX2"	""	"17q12 copy number variation syndrome"	"1"	"0"	"21.0"	"11.4"	"32.4"	"28.9"	"28.6"	"27.4"	"56.3"	"4.6"	"418.3"	"454.3"	"804.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBC3"	"DNA (cytosine-5)-methyltransferase 3B OS=Homo sapiens OX=9606 GN=DNMT3B PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"853"	"95.7"	"8.43"	"545.95"	"8.03"	"2"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf00855, Pf17980"	"1789"	"ENSG00000088305"	"DNMT3B"	"A2A2E2; B4DSM8; B4DSU1; E1P5M6; E1P5M7; E7EN63; E9PBF2; hsa:1789; Q9UBC3; Q9UBD4; Q9UJQ5; Q9UKA6; Q9UNE5; Q9Y5R9; Q9Y5S0"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Mesodermal commitment pathway; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"10"	"0"	"28.8"	"21.5"	"30.9"	"30.7"	"29.3"	"26.0"	"54.8"	"0.5"	"301.9"	"306.4"	"583.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38432"	"Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"576"	"62.6"	"9.07"	"734.05"	"8.02"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15862"	"8161"	"ENSG00000121058"	"COIL"	"B2R931; hsa:8161; P38432"	""	""	"0"	"0"	"157.7"	"106.0"	"137.0"	"139.8"	"116.6"	"133.3"	"253.4"	"0.0"	"1725.7"	"1782.5"	"2808.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95425"	"Supervillin OS=Homo sapiens OX=9606 GN=SVIL PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"2214"	"247.6"	"6.98"	"359.78"	"8.02"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf02209"	"6840"	"ENSG00000197321"	"SVIL"	"D3DRW9; hsa:6840; M1J557; O60611; O60612; O95425; Q5VZK5; Q5VZK6; Q9H1R7"	""	""	"0"	"0"	"6.4"	"4.0"	"5.3"	"6.2"	"4.7"	"3.8"	"13.6"	"1.9"	"199.9"	"220.0"	"422.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15294"	"UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3"	"0.000"	""	"3"	"3"	"4"	"3"	"1046"	"116.9"	"6.70"	"571.84"	"7.99"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00515, Pf13181, Pf13414, Pf13424, Pf13844"	"8473"	"ENSG00000147162"	"OGT"	"hsa:8473; O15294; Q7Z3K0; Q8WWM8; Q96CC1; Q9UG57"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Regulation of necroptotic cell death; HATs acetylate histones"	"Ectoderm differentiation; Ectoderm differentiation; Pleural mesothelioma"	"8"	"0"	"89.5"	"59.9"	"76.6"	"64.1"	"90.7"	"63.3"	"94.5"	"3.7"	"569.2"	"587.7"	"1117.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14531"	"Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"572"	"61.8"	"7.09"	"1036.23"	"7.99"	"3"	"3"	"developmental processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf01979"	"10570"	"ENSG00000151640"	"DPYSL4"	"B2RMQ1; D3DRG5; hsa:10570; O00240; O14531; Q5T0Q7"	"CRMPs in Sema3A signaling"	""	"1"	"0"	"4.7"	"8.4"	"10.3"	"5.9"	"11.1"	"8.6"	"18.1"	"2.1"	"515.5"	"544.9"	"1138.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82673"	"28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"323"	"36.8"	"8.24"	"231.76"	"7.98"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10213"	"60488"	"ENSG00000061794"	"MRPS35"	"hsa:60488; P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14; Q9P1R5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"176.3"	"126.2"	"155.2"	"158.7"	"169.5"	"170.5"	"259.6"	"4.1"	"645.8"	"600.7"	"1106.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16698"	"2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"335"	"36.0"	"9.28"	"748.36"	"7.98"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf13561"	"1666"	"ENSG00000104325"	"DECR1"	"B7Z6B8; hsa:1666; Q16698; Q2M304; Q93085"	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; VEGFA-VEGFR2 signaling"	"4"	"0"	"123.1"	"98.9"	"130.2"	"131.3"	"124.7"	"114.2"	"204.2"	"0.0"	"1385.6"	"1358.6"	"2490.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99497"	"Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2"	"0.000"	""	"17"	"3"	"5"	"3"	"189"	"19.9"	"6.79"	"1061.44"	"7.95"	"3"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01965"	"11315"	"ENSG00000116288"	"PARK7"	"B2R4Z1; hsa:11315; O14805; Q6DR95; Q7LFU2; Q99497"	"Late endosomal microautophagy; Aggrephagy; SUMOylation of transcription cofactors; Chaperone Mediated Autophagy"	"Androgen receptor signaling pathway; Synaptic vesicle pathway; Parkinson's disease pathway"	"7"	"0"	"307.8"	"246.7"	"294.5"	"294.7"	"268.8"	"258.6"	"342.2"	"0.0"	"626.8"	"690.3"	"1083.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6YN16"	"Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"418"	"45.4"	"7.99"	"752.76"	"7.93"	"2"	"2"	""	"mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf02036"	"84263"	"ENSG00000119471"	"HSDL2"	"A8K1L4; A8K8X1; A8MSV3; hsa:84263; Q658M8; Q6YN16; Q9BT58"	""	""	"0"	"0"	"40.0"	"29.4"	"47.9"	"44.2"	"37.1"	"43.1"	"51.0"	"4.5"	"300.5"	"302.8"	"645.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RN5"	"Mediator of RNA polymerase II transcription subunit 15 OS=Homo sapiens OX=9606 GN=MED15 PE=1 SV=2"	"0.000"	""	"2"	"1"	"4"	"1"	"788"	"86.7"	"9.42"	"841.79"	"7.93"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf09606"	"51586"	"ENSG00000099917"	"MED15"	"D3DX31; D3DX32; hsa:51586; O15413; Q6IC31; Q8NF16; Q96CT0; Q96IH7; Q96RN5; Q9P1T3"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; 22q11.2 copy number variation syndrome"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03164"	"Histone-lysine N-methyltransferase 2A OS=Homo sapiens OX=9606 GN=KMT2A PE=1 SV=5"	"0.000"	""	"1"	"2"	"4"	"2"	"3969"	"431.5"	"9.09"	"781.43"	"7.93"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"4297"	"ENSG00000118058"	"KMT2A"	"E9PQG7; hsa:4297; Q03164; Q13743; Q13744; Q14845; Q16364; Q59FF2; Q6UBD1; Q9HBJ3; Q9UD94; Q9UMA3"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation of granulopoiesis; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines"	"Histone modifications"	"6"	"0"	"38.3"	"26.5"	"37.0"	"36.8"	"35.8"	"43.3"	"60.2"	"1.9"	"856.9"	"873.3"	"2044.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUD2"	"ELKS/Rab6-interacting/CAST family member 1 OS=Homo sapiens OX=9606 GN=ERC1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1116"	"128.0"	"5.97"	"931.85"	"7.93"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf09457, Pf10174"	"23085"	"ENSG00000082805"	"ERC1"	"A2RU77; A7E295; D3DUP7; D3DUP8; hsa:23085; Q6NVK2; Q8IUD2; Q8IUD3; Q8IUD4; Q8IUD5; Q8NAS1; Q9NXN5; Q9UIK7; Q9UPS1"	""	""	"0"	"0"	"44.7"	"34.8"	"52.3"	"48.0"	"44.8"	"43.0"	"92.2"	"0.0"	"846.7"	"861.3"	"1722.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB49"	"Phospholipid-transporting ATPase IG OS=Homo sapiens OX=9606 GN=ATP11C PE=1 SV=3"	"0.000"	""	"3"	"3"	"6"	"3"	"1132"	"129.4"	"6.67"	"933.38"	"7.92"	"3"	"3"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf13246, Pf16209, Pf16212"	"286410"	"ENSG00000101974"	"ATP11C"	"hsa:286410; Q5JT69; Q5JT70; Q5JT71; Q5JT72; Q5JT73; Q6ZND5; Q6ZU50; Q6ZUP7; Q70IJ9; Q70IK0; Q8NB49; Q8WX24"	"Ion transport by P-type ATPases"	"Complement system in neuronal development and plasticity"	"2"	"0"	"17.2"	"8.1"	"21.9"	"16.5"	"10.3"	"13.1"	"20.4"	"2.2"	"169.2"	"170.5"	"366.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H425"	"Uncharacterized protein C1orf198 OS=Homo sapiens OX=9606 GN=C1orf198 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"327"	"36.3"	"5.72"	"886.96"	"7.91"	"1"	"2"	""	"cytosol"	""	"Pf15797"	"84886"	"ENSG00000119280"	"C1orf198"	"A8K8R8; B3KTW1; G5EA08; hsa:84886; Q9H425"	""	""	"0"	"0"	"18.5"	"8.2"	"9.5"	"12.8"	"13.2"	"16.3"	"28.8"	"1.3"	"184.5"	"158.3"	"360.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13526"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1"	"0.000"	""	"22"	"2"	"3"	"2"	"163"	"18.2"	"8.82"	"585.14"	"7.90"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00639"	"5300"	"ENSG00000127445"	"PIN1"	"A8K4V9; hsa:5300; Q13526; Q53X75"	"Regulation of TP53 Activity through Phosphorylation; ISG15 antiviral mechanism; Negative regulators of DDX58/IFIH1 signaling; PI5P Regulates TP53 Acetylation; RHO GTPases Activate NADPH Oxidases"	"Novel intracellular components of RIG-I-like receptor pathway"	"6"	"0"	"18.1"	"14.3"	"11.3"	"14.8"	"8.7"	"14.2"	"24.4"	"0.8"	"126.4"	"129.4"	"383.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WG5"	"Myotubularin-related protein 13 OS=Homo sapiens OX=9606 GN=SBF2 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1849"	"208.3"	"7.06"	"986.57"	"7.89"	"2"	"2"	"other metabolic processes;developmental processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"81846"	"ENSG00000133812"	"SBF2"	"hsa:81846; Q3MJF0; Q68DQ3; Q6P459; Q6PJD1; Q7Z325; Q7Z621; Q86VE2; Q86WG5; Q96FE2; Q9C097"	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the plasma membrane"	"Intracellular trafficking proteins involved in CMT neuropathy"	"3"	"0"	"5.8"	"8.5"	"16.8"	"10.4"	"13.6"	"10.6"	"20.7"	"0.9"	"196.0"	"168.1"	"317.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z7F7"	"39S ribosomal protein L55, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL55 PE=1 SV=1"	"0.000"	""	"20"	"2"	"3"	"2"	"128"	"15.1"	"11.15"	"477.33"	"7.88"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09776"	"128308"	"ENSG00000162910"	"MRPL55"	"hsa:128308; Q5TBY3; Q5TBY6; Q6UWI8; Q7Z7F7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"18.6"	"17.2"	"19.2"	"21.8"	"20.6"	"26.7"	"73.5"	"0.0"	"449.3"	"475.6"	"998.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14974"	"Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"876"	"97.1"	"4.78"	"749.86"	"7.88"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf03810"	"3837"	"ENSG00000108424"	"KPNB1"	"B7ZAV6; D3DTT3; hsa:3837; Q14637; Q14974; Q53XN2; Q96J27"	"Assembly of the ORC complex at the origin of replication; Neutrophil degranulation; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Nuclear import of Rev protein; Apoptosis induced DNA fragmentation; Interferon alpha/beta signaling; Regulation of cholesterol biosynthesis by SREBP (SREBF); SARS-CoV-1 activates/modulates innate immune responses; Initiation of Nuclear Envelope (NE) Reformation; Postmitotic nuclear pore complex (NPC) reformation; Inhibition of nitric oxide production"	"Sterol regulatory element-binding proteins (SREBP) signaling; 22q11.2 copy number variation syndrome"	"15"	"0"	"35.2"	"26.4"	"47.9"	"40.0"	"38.9"	"39.2"	"84.6"	"0.0"	"818.9"	"870.5"	"1813.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI98"	"INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"192"	"20.6"	"10.02"	"964.23"	"7.86"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08265"	"125476"	"ENSG00000153391"	"INO80C"	"B4DUI4; E9PCS7; hsa:125476; Q6PI98; Q86WR1; Q8N994"	"UCH proteinases; DNA Damage Recognition in GG-NER"	""	"2"	"0"	"20.3"	"14.0"	"24.7"	"17.2"	"17.4"	"14.9"	"26.4"	"0.0"	"295.1"	"289.6"	"537.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13884"	"Beta-1-syntrophin OS=Homo sapiens OX=9606 GN=SNTB1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"538"	"58.0"	"8.63"	"300.12"	"7.85"	"1"	"2"	"other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00595, Pf18012"	"6641"	"ENSG00000172164"	"SNTB1"	"A8K9E0; hsa:6641; O14912; Q13884; Q4KMG8"	""	"IL-18 signaling pathway; 13q12.12 copy number variation"	"2"	"0"	"7.1"	"8.5"	"4.8"	"6.6"	"6.3"	"6.6"	"12.2"	"3.3"	"102.5"	"101.4"	"201.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14136"	"Glial fibrillary acidic protein OS=Homo sapiens OX=9606 GN=GFAP PE=1 SV=1"	"0.000"	""	"8"	"3"	"4"	"1"	"432"	"49.9"	"5.52"	"440.06"	"7.85"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"2670"	"ENSG00000131095"	"GFAP"	"A7REI1; B2RD44; D3DX59; E9PAX3; hsa:2670; P14136; Q53H98; Q5D055; Q6ZQS3; Q7Z5J6; Q7Z5J7; Q96KS4; Q96P18; Q9UFD0"	"Chaperone Mediated Autophagy; Nuclear signaling by ERBB4"	"Neural crest differentiation; Spinal cord injury; Neuroinflammation and glutamatergic signaling"	"5"	"0"	"3.3"	"0.0"	"0.0"	"3.1"	"2.4"	"0.0"	"3.9"	"1.2"	"93.0"	"100.0"	"161.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18858"	"DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"919"	"101.7"	"5.62"	"444.10"	"7.84"	"1"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01068, Pf04675, Pf04679"	"3978"	"ENSG00000105486"	"LIG1"	"B2RAI8; B4DTU4; hsa:3978; P18858; Q2TB12; Q32P23"	"Gap-filling DNA repair synthesis and ligation in TC-NER; Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Processive synthesis on the lagging strand; Gap-filling DNA repair synthesis and ligation in GG-NER; Processive synthesis on the C-strand of the telomere; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"14"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"29.5"	"26.7"	"123.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2S6"	"Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1"	"0.000"	""	"36"	"4"	"9"	"3"	"64"	"7.1"	"9.99"	"1992.92"	"7.84"	"4"	"3"	""	""	""	"Pf09072"	"51372"	"ENSG00000232112"	"TMA7"	"hsa:51372; Q9P052; Q9Y2S6"	""	""	"0"	"0"	"849.7"	"795.0"	"958.5"	"873.2"	"668.9"	"760.3"	"1196.0"	"0.0"	"3337.7"	"3338.5"	"6225.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP79"	"Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"307"	"33.9"	"6.29"	"763.67"	"7.83"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04652, Pf18097"	"51534"	"ENSG00000009844"	"VTA1"	"B4DW55; E1P594; E7ETQ7; hsa:51534; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9NP79; Q9P0Q0"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	""	"2"	"0"	"33.3"	"32.2"	"46.5"	"46.7"	"43.1"	"29.9"	"62.8"	"2.8"	"655.8"	"684.1"	"1724.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FK6"	"WD repeat-containing protein 89 OS=Homo sapiens OX=9606 GN=WDR89 PE=2 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"387"	"43.2"	"6.13"	"872.78"	"7.82"	"2"	"2"	"developmental processes"	""	""	"Pf00400"	"112840"	"ENSG00000140006"	"WDR89"	"hsa:112840; Q96FK6"	""	""	"0"	"0"	"32.1"	"17.8"	"35.1"	"30.5"	"38.4"	"32.0"	"58.6"	"7.1"	"712.0"	"727.2"	"1669.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y613"	"FH1/FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1164"	"126.5"	"6.39"	"865.04"	"7.81"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf18382"	"29109"	"ENSG00000135723"	"FHOD1"	"hsa:29109; Q59F76; Q6Y1F2; Q76MS8; Q8N521; Q9Y613"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"31.6"	"21.9"	"23.1"	"25.5"	"23.6"	"29.8"	"33.3"	"3.2"	"232.1"	"197.2"	"428.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60520"	"Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1"	"0.000"	""	"16"	"2"	"4"	"2"	"117"	"13.7"	"8.10"	"813.24"	"7.81"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11345"	"ENSG00000034713"	"GABARAPL2"	"hsa:11345; O08765; P60520; Q6FG91; Q9DCP8; Q9UQF7"	"Macroautophagy; TBC/RABGAPs"	"Network map of SARS-CoV-2 signaling pathway; 2q37 copy number variation syndrome"	"4"	"0"	"50.1"	"36.6"	"43.0"	"39.3"	"42.4"	"46.7"	"83.0"	"0.0"	"1268.9"	"1312.1"	"2272.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09234"	"U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1"	"0.000"	""	"13"	"2"	"3"	"2"	"159"	"17.4"	"9.67"	"399.37"	"7.81"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06220"	"6631"	"ENSG00000124562"	"SNRPC"	"hsa:6631; P09234; Q5TAL3"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"117.7"	"51.6"	"121.8"	"94.4"	"100.6"	"78.1"	"133.6"	"0.0"	"994.0"	"912.0"	"2938.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T653"	"39S ribosomal protein L2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL2 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"305"	"33.3"	"11.30"	"1002.48"	"7.80"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00181, Pf03947"	"51069"	"ENSG00000112651"	"MRPL2"	"B2RC56; hsa:51069; Q5T653; Q8WUL1; Q96Q56; Q9Y311"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"14.3"	"15.1"	"11.7"	"14.0"	"16.6"	"10.9"	"31.8"	"0.0"	"108.6"	"98.9"	"205.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75380"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6 PE=1 SV=1"	"0.000"	""	"20"	"2"	"3"	"2"	"124"	"13.7"	"8.28"	"558.03"	"7.80"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf10276"	"4726"	"ENSG00000145494"	"NDUFS6"	"hsa:4726; O75380"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"26.6"	"16.5"	"36.0"	"29.5"	"30.5"	"28.8"	"48.9"	"0.0"	"388.2"	"307.3"	"1046.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCB2"	"CaM kinase-like vesicle-associated protein OS=Homo sapiens OX=9606 GN=CAMKV PE=2 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"501"	"54.3"	"5.55"	"786.28"	"7.80"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"79012"	"ENSG00000164076"	"CAMKV"	"A6NFD4; hsa:79012; Q6FIB8; Q8NBS8; Q8NC85; Q8NCB2; Q8NDU4; Q8WTT8; Q9BQC9; Q9H0Q5"	""	""	"0"	"0"	"21.7"	"24.1"	"34.4"	"27.0"	"27.3"	"32.6"	"73.5"	"3.0"	"300.0"	"328.7"	"472.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62877"	"E3 ubiquitin-protein ligase RBX1 OS=Homo sapiens OX=9606 GN=RBX1 PE=1 SV=1"	"0.000"	""	"13"	"1"	"4"	"1"	"108"	"12.3"	"6.96"	"719.25"	"7.79"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12678"	"9978"	"ENSG00000100387"	"RBX1"	"B2RDY1; hsa:9978; P62877; Q8N6Z8; Q9D1S2; Q9WUK9; Q9Y254"	"Potential therapeutics for SARS; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Degradation of DVL; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of BACH1 activity; NOTCH1 Intracellular Domain Regulates Transcription; Formation of TC-NER Pre-Incision Complex; Prolactin receptor signaling; DNA Damage Recognition in GG-NER; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"Cell cycle; Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; NRF2-ARE regulation; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Nucleotide excision repair; Hijack of ubiquitination by SARS-CoV-2; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 1p36 copy number variation syndrome"	"46"	"0"	"32.4"	"28.4"	"26.8"	"34.1"	"31.0"	"25.4"	"61.2"	"0.0"	"756.0"	"816.0"	"1652.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75616"	"GTPase Era, mitochondrial OS=Homo sapiens OX=9606 GN=ERAL1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"437"	"48.3"	"8.84"	"856.09"	"7.79"	"2"	"2"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01926"	"26284"	"ENSG00000132591"	"ERAL1"	"B3KN21; C9JEC6; hsa:26284; O75616; O75617; Q8WUY4; Q96LE2; Q96TC0"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"Primary ovarian insufficiency"	"4"	"0"	"25.3"	"21.1"	"27.3"	"22.4"	"30.0"	"21.6"	"64.3"	"0.0"	"398.4"	"415.9"	"771.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29590"	"Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"882"	"97.5"	"6.21"	"340.26"	"7.78"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00643, Pf12126"	"5371"	"ENSG00000140464"	"PML"	"E9PBR7; hsa:5371; P29590; P29591; P29592; P29593; Q00755; Q15959; Q59FP9; Q8WUA0; Q96S41; Q9BPW2; Q9BWP7; Q9BZX6; Q9BZX7; Q9BZX8; Q9BZX9; Q9BZY0; Q9BZY2; Q9BZY3"	"Regulation of PTEN localization; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Interferon gamma signaling; Regulation of TP53 Activity through Acetylation; Regulation of RUNX1 Expression and Activity"	"miRNA regulation of DNA damage response; Wnt/beta-catenin signaling pathway in leukemia; p53 transcriptional gene network; DNA damage response"	"11"	"0"	"50.9"	"38.2"	"55.3"	"42.6"	"44.1"	"37.7"	"72.0"	"2.5"	"201.9"	"201.7"	"444.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NAV1"	"Pre-mRNA-splicing factor 38A OS=Homo sapiens OX=9606 GN=PRPF38A PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"312"	"37.5"	"9.96"	"903.58"	"7.77"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371, Pf12871"	"84950"	"ENSG00000134748"	"PRPF38A"	"hsa:84950; Q8NAV1; Q96JW1; Q9BVZ8"	"mRNA Splicing - Major Pathway"	"MECP2 and associated Rett syndrome"	"2"	"0"	"49.7"	"38.0"	"67.2"	"49.3"	"55.4"	"41.0"	"105.9"	"1.4"	"768.5"	"770.2"	"1783.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPY6"	"Wiskott-Aldrich syndrome protein family member 3 OS=Homo sapiens OX=9606 GN=WASF3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"1"	"502"	"55.3"	"6.43"	"872.91"	"7.77"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10810"	"ENSG00000132970"	"WASF3"	"hsa:10810; O94974; Q86VQ2; Q9UPY6"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; VEGFA-VEGFR2 Pathway"	""	"5"	"1"	"13.2"	"11.0"	"7.4"	"8.5"	"12.7"	"10.1"	"20.8"	"0.4"	"115.9"	"123.5"	"210.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35914"	"Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"325"	"34.3"	"8.54"	"531.24"	"7.77"	"1"	"2"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00682"	"3155"	"ENSG00000117305"	"HMGCL"	"B4DUP4; B7UCC6; D3Y5K7; hsa:3155; P35914; Q6IBC0; Q96FP8"	"Peroxisomal protein import; Synthesis of Ketone Bodies"	"Amino acid metabolism"	"3"	"0"	"62.4"	"48.1"	"56.7"	"62.7"	"58.4"	"59.2"	"71.0"	"0.0"	"453.1"	"485.5"	"1079.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95881"	"Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1"	"0.000"	""	"13"	"2"	"3"	"2"	"172"	"19.2"	"5.40"	"613.68"	"7.76"	"1"	"2"	"other biological processes"	"ER/Golgi"	"other molecular function"	"Pf13899"	"51060"	"ENSG00000117862"	"TXNDC12"	"B3KQS0; hsa:51060; O95881; Q5T1T4; Q96H50"	""	""	"0"	"0"	"133.4"	"111.3"	"163.3"	"172.4"	"177.1"	"127.6"	"205.6"	"0.0"	"496.5"	"488.8"	"867.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61927"	"60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2"	"0.000"	""	"26"	"3"	"5"	"3"	"97"	"11.1"	"11.74"	"535.75"	"7.74"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01907"	"6167"	"ENSG00000145592"	"RPL37"	"B2R4H2; hsa:6167; P02403; P61927; Q6IBB4; Q99883"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"383.6"	"411.2"	"281.7"	"331.1"	"276.7"	"310.8"	"1083.9"	"0.0"	"1607.9"	"1767.2"	"2509.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15435"	"Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"360"	"41.5"	"4.91"	"828.66"	"7.74"	"2"	"2"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf14580"	"5510"	"ENSG00000115685"	"PPP1R7"	"B4DFD4; B5MCY6; hsa:5510; Q15435; Q9UQE5; Q9UQE6; Q9Y6K4"	""	"2q37 copy number variation syndrome"	"1"	"0"	"10.8"	"8.6"	"6.3"	"9.5"	"9.9"	"11.5"	"14.0"	"1.1"	"239.1"	"242.1"	"525.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQT4"	"Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"235"	"25.2"	"7.59"	"566.20"	"7.72"	"1"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"56915"	"ENSG00000077348"	"EXOSC5"	"hsa:56915; Q32Q81; Q8NG16; Q96I89; Q9NQT4"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"18.0"	"14.4"	"21.6"	"29.2"	"33.1"	"15.2"	"63.3"	"0.0"	"295.0"	"310.2"	"803.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBK8"	"Methionine synthase reductase OS=Homo sapiens OX=9606 GN=MTRR PE=1 SV=4"	"0.000"	""	"3"	"2"	"4"	"2"	"698"	"77.6"	"6.49"	"781.94"	"7.72"	"2"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf00175, Pf00258, Pf00667"	"4552"	"ENSG00000124275"	"MTRR"	"hsa:4552; O60471; Q32MA9; Q7Z4M8; Q9UBK8"	"Methylation; Cobalamin (Cbl) metabolism; Sulfur amino acid metabolism; Defective MTRR causes HMAE; Defective MTR causes HMAG"	"Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Male infertility"	"9"	"0"	"0.0"	"0.0"	"2.1"	"2.4"	"0.0"	"3.6"	"7.2"	"4.7"	"151.3"	"144.1"	"322.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4J8"	"Dystrobrevin alpha OS=Homo sapiens OX=9606 GN=DTNA PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"1"	"743"	"83.8"	"6.89"	"358.27"	"7.72"	"1"	"2"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1837"	"ENSG00000134769"	"DTNA"	"A8K541; A8MSZ0; A8MUY4; B4DGS6; B4DIR0; B4DIU8; hsa:1837; M0QYX6; M0R397; O15332; O15333; O75697; Q13197; Q13198; Q13199; Q13498; Q13499; Q13500; Q59GK7; Q9BS59; Q9Y4J8"	""	"13q12.12 copy number variation"	"1"	"1"	"18.7"	"14.3"	"25.4"	"31.6"	"32.3"	"15.9"	"37.9"	"0.0"	"345.3"	"324.9"	"600.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24941"	"Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2"	"0.000"	""	"10"	"2"	"4"	"2"	"298"	"33.9"	"8.68"	"841.63"	"7.70"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1017"	"ENSG00000123374"	"CDK2"	"A8K7C6; hsa:1017; O75100; P24941"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Factors involved in megakaryocyte development and platelet production; Processing of DNA double-strand break ends; Cyclin A/B1/B2 associated events during G2/M transition; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Transcriptional regulation of granulopoiesis; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response; PTK6 Regulates Cell Cycle"	"miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Vitamin D receptor pathway; PI3K-Akt signaling pathway; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA replication; p53 transcriptional gene network; Pleural mesothelioma; Sphingolipid metabolism in senescence; Urotensin-II-mediated signaling pathway; ID signaling pathway; TROP2 regulatory signaling; DNA damage response"	"47"	"0"	"13.3"	"9.9"	"16.2"	"10.8"	"12.2"	"13.1"	"24.5"	"1.0"	"214.0"	"197.8"	"416.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q56NI9"	"N-acetyltransferase ESCO2 OS=Homo sapiens OX=9606 GN=ESCO2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"601"	"68.3"	"9.39"	"808.83"	"7.69"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf13878, Pf13880"	"157570"	"ENSG00000171320"	"ESCO2"	"B3KW59; hsa:157570; Q49AP4; Q56NI9"	"Establishment of Sister Chromatid Cohesion"	"Cohesin complex - Cornelia de Lange syndrome"	"2"	"0"	"5.2"	"5.2"	"11.5"	"7.7"	"7.2"	"9.0"	"27.8"	"4.8"	"273.1"	"311.4"	"516.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0B5"	"Palmitoyltransferase ZDHHC5 OS=Homo sapiens OX=9606 GN=ZDHHC5 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"715"	"77.5"	"9.01"	"233.04"	"7.69"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01529"	"25921"	"ENSG00000156599"	"ZDHHC5"	"hsa:25921; Q2TGF0; Q6ZMF0; Q8TAK8; Q9C0B5; Q9H923; Q9UFI7"	"Maturation of spike protein"	""	"1"	"0"	"22.8"	"12.1"	"18.6"	"14.3"	"15.6"	"18.3"	"27.0"	"0.0"	"258.2"	"233.1"	"506.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6DN90"	"IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"963"	"108.2"	"6.93"	"994.24"	"7.68"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01369, Pf16453"	"9922"	"ENSG00000144711"	"IQSEC1"	"A0A087WWK8; hsa:9922; O94863; Q6DN90; Q96D85"	""	"EGF/EGFR signaling pathway"	"1"	"0"	"36.7"	"23.2"	"38.7"	"29.3"	"29.9"	"34.5"	"73.8"	"0.0"	"622.7"	"596.3"	"1106.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30260"	"Cell division cycle protein 27 homolog OS=Homo sapiens OX=9606 GN=CDC27 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"824"	"91.8"	"7.02"	"506.93"	"7.66"	"1"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf12895"	"996"	"ENSG00000004897"	"CDC27"	"G3V1C4; hsa:996; P30260; Q16349; Q96F35"	"Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"Cell cycle; 2q21.1 copy number variation syndrome"	"20"	"0"	"18.4"	"16.8"	"17.3"	"12.5"	"20.6"	"12.4"	"30.4"	"0.0"	"257.1"	"281.3"	"782.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C1"	"Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2"	"0.000"	""	"25"	"3"	"5"	"3"	"178"	"21.2"	"9.94"	"1600.83"	"7.64"	"3"	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf09420"	"51491"	"ENSG00000048162"	"NOP16"	"B4DV13; D6RGD3; hsa:51491; Q05D05; Q6IAI6; Q6PIM0; Q8IXL5; Q9Y3C1"	""	"5q35 copy number variation"	"1"	"0"	"77.8"	"72.3"	"83.6"	"96.0"	"82.2"	"84.7"	"270.3"	"0.0"	"745.6"	"745.8"	"1203.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36957"	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4"	"0.000"	""	"4"	"2"	"4"	"2"	"453"	"48.7"	"8.95"	"838.11"	"7.63"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00198, Pf00364"	"1743"	"ENSG00000119689"	"DLST"	"B7Z5W8; E7ESY5; hsa:1743; P36957; Q7LDY7; Q9BQ32"	"Citric acid cycle (TCA cycle); Lysine catabolism; Glyoxylate metabolism and glycine degradation"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Metabolic reprogramming in colon cancer; 7q11.23 copy number variation syndrome; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"10"	"0"	"306.1"	"184.1"	"242.8"	"241.8"	"221.9"	"258.6"	"150.2"	"0.0"	"584.6"	"558.2"	"1090.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12802"	"A-kinase anchor protein 13 OS=Homo sapiens OX=9606 GN=AKAP13 PE=1 SV=2"	"0.000"	""	"1"	"3"	"6"	"3"	"2813"	"307.4"	"5.24"	"845.50"	"7.62"	"3"	"3"	"transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf00621, Pf10522"	"11214"	"ENSG00000170776"	"AKAP13"	"hsa:11214; Q12802; Q14572; Q59FP6; Q86W90; Q8WXQ6; Q96JP6; Q96P79; Q9Y5T0; Q9Y5T6"	"RHOC GTPase cycle; RHOA GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; G protein signaling pathways"	"8"	"0"	"38.3"	"28.7"	"52.0"	"36.0"	"33.8"	"40.0"	"66.1"	"1.0"	"502.5"	"471.0"	"948.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q76FK4"	"Nucleolar protein 8 OS=Homo sapiens OX=9606 GN=NOL8 PE=1 SV=1"	"0.000"	""	"2"	"3"	"6"	"3"	"1167"	"131.5"	"7.09"	"692.93"	"7.62"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"55035"	"ENSG00000198000"	"NOL8"	"hsa:55035; Q5TCC7; Q5TCC8; Q5TCD3; Q5TCD5; Q5TCD6; Q5TCD7; Q76D35; Q76FK4; Q7L3E2; Q9H586; Q9H795; Q9H7W7; Q9H9J6; Q9NWA4; Q9NWM4"	""	""	"0"	"0"	"93.7"	"71.2"	"71.5"	"70.5"	"59.4"	"69.5"	"191.4"	"1.9"	"641.7"	"597.2"	"1188.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P62873"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3"	""	""	"9"	"2"	"2"	"2"	"340"	"37.4"	"6.00"	""	"7.61"	""	"2"	"cell-cell signaling;cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2782"	"ENSG00000078369"	"GNB1"	"B1AJZ7; hsa:2782; P04697; P04901; P62873; Q1RMY8"	"Thrombin signalling through proteinase activated receptors (PARs); G alpha (12/13) signalling events; Olfactory Signaling Pathway; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Sensory perception of sweet, bitter, and umami (glutamate) taste; Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Inactivation, recovery and regulation of the phototransduction cascade; Glucagon signaling in metabolic regulation; Activation of the phototransduction cascade"	"Nicotine effect on dopaminergic neurons; Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; 1p36 copy number variation syndrome; Calcium regulation in cardiac cells; Estrogen signaling pathway"	"45"	"0"	"40.1"	"43.9"	"39.3"	"50.1"	"38.8"	"24.8"	"90.7"	"0.0"	"730.3"	"790.1"	"1308.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60749"	"Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"519"	"58.4"	"5.12"	"906.00"	"7.61"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6643"	"ENSG00000205302"	"SNX2"	"B3KN44; B4DEK4; B7Z408; hsa:6643; O43650; O60749; P82862; Q53XK8; Q597H6; Q9BTS8"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	"19.0"	"18.5"	"18.7"	"16.1"	"18.3"	"16.5"	"31.6"	"8.6"	"460.9"	"469.9"	"1138.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43709"	"Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2"	"0.000"	""	"16"	"3"	"4"	"3"	"281"	"31.9"	"8.73"	"501.72"	"7.59"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08241, Pf12589"	"114049"	"ENSG00000071462"	"BUD23"	"A8K501; C9K060; hsa:114049; O43709; Q96P12; Q9BQ58; Q9HBP9"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"7q11.23 copy number variation syndrome"	"3"	"0"	"111.9"	"87.1"	"97.4"	"97.6"	"89.3"	"103.0"	"149.7"	"0.0"	"1073.3"	"1159.8"	"2235.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0U3"	"Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"644"	"73.4"	"8.47"	"720.45"	"7.57"	"2"	"2"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf02902"	"29843"	"ENSG00000079387"	"SENP1"	"A8K7P5; hsa:29843; Q86XC8; Q9P0U3"	"RHOF GTPase cycle; SUMO is proteolytically processed"	""	"2"	"0"	"60.4"	"45.1"	"50.5"	"51.3"	"57.4"	"42.5"	"105.9"	"0.0"	"513.2"	"585.5"	"1015.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60684"	"Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"536"	"60.0"	"4.98"	"746.34"	"7.57"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"23633"	"ENSG00000025800"	"KPNA6"	"B2RDC7; D3DPP5; hsa:23633; O60684; Q5VVU3"	"Assembly of the ORC complex at the origin of replication"	""	"1"	"0"	"20.7"	"10.8"	"20.8"	"16.4"	"19.6"	"16.3"	"63.4"	"2.8"	"630.6"	"618.3"	"1349.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13416"	"Origin recognition complex subunit 2 OS=Homo sapiens OX=9606 GN=ORC2 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"577"	"65.9"	"6.51"	""	"7.56"	""	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04084"	"4999"	"ENSG00000115942"	"ORC2"	"hsa:4999; Q13204; Q13416; Q53TX5"	"Orc1 removal from chromatin; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"10"	"0"	"6.0"	"3.8"	"9.0"	"7.9"	"8.3"	"6.4"	"15.4"	"0.0"	"122.6"	"108.0"	"224.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJS0"	"Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"675"	"74.1"	"8.62"	"982.70"	"7.56"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"10165"	"ENSG00000004864"	"SLC25A13"	"hsa:10165; O14566; O14575; Q546F9; Q9NZW1; Q9UJS0; Q9UNI7"	"Gluconeogenesis; Mitochondrial protein import; Aspartate and asparagine metabolism"	""	"3"	"0"	"6.9"	"2.4"	"8.7"	"7.9"	"5.7"	"3.7"	"17.9"	"1.6"	"128.4"	"140.1"	"306.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6KC79"	"Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2"	"0.000"	""	"0"	"1"	"4"	"1"	"2804"	"315.9"	"7.91"	"743.07"	"7.56"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12765, Pf12830"	"25836"	"ENSG00000164190"	"NIPBL"	"hsa:25836; Q6KC79; Q6KCD6; Q6N080; Q6ZT92; Q7Z2E6; Q8N4M5; Q9Y6Y3; Q9Y6Y4"	"Cohesin Loading onto Chromatin"	"Cohesin complex - Cornelia de Lange syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"3"	"0"	"9.3"	"2.6"	"11.6"	"5.6"	"6.0"	"3.2"	"23.4"	"5.5"	"190.7"	"158.8"	"431.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2M7"	"Cingulin OS=Homo sapiens OX=9606 GN=CGN PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1197"	"136.3"	"5.54"	"702.27"	"7.55"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"2.2"	"2.2"	"6.1"	"0.0"	"6.4"	"3.0"	"13.0"	"2.6"	"73.3"	"82.1"	"139.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99996"	"A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4"	"0.000"	""	"1"	"3"	"5"	"2"	"3907"	"452.7"	"4.98"	"551.29"	"7.53"	"2"	"3"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf10495"	"10142"	"ENSG00000127914"	"AKAP9"	"A4D1F0; A4D1F2; A4D1F4; hsa:10142; O14869; O43355; O94895; Q75N20; Q99996; Q9UQH3; Q9UQQ4; Q9Y6B8; Q9Y6Y2"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by BRAF and RAF1 fusions; Phase 3 - rapid repolarisation; Phase 2 - plateau phase"	"G protein signaling pathways; NO/cGMP/PKG mediated neuroprotection"	"12"	"0"	"13.6"	"18.0"	"24.3"	"20.4"	"17.9"	"21.1"	"110.7"	"0.0"	"398.2"	"436.8"	"905.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60941"	"Dystrobrevin beta OS=Homo sapiens OX=9606 GN=DTNB PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"1"	"627"	"71.3"	"7.91"	"711.58"	"7.49"	"2"	"2"	"cell-cell signaling;developmental processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1838"	"ENSG00000138101"	"DTNB"	"B7Z733; F5GZG4; G5E9F6; hsa:1838; O43782; O60881; O60941; O75538; Q86VR4; Q96AW0; Q9UE14; Q9UE15; Q9UE16"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.9"	"0.9"	"41.8"	"39.0"	"94.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGM6"	"Tryptophan--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=WARS2 PE=1 SV=1"	"0.000"	""	"11"	"3"	"3"	"3"	"360"	"40.1"	"9.28"	"356.16"	"7.48"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00579"	"10352"	"ENSG00000116874"	"WARS2"	"B1ALR1; B2R9D4; hsa:10352; Q53FT4; Q5VUD2; Q86TQ0; Q9UGM6"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"33.8"	"26.5"	"33.6"	"39.6"	"34.3"	"38.4"	"71.8"	"1.0"	"703.8"	"804.8"	"1584.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84022"	"Mothers against decapentaplegic homolog 3 OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"425"	"48.1"	"7.15"	"625.08"	"7.47"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf03165, Pf03166"	"4088"	"ENSG00000166949"	"SMAD3"	"A8K4B6; B7Z4Z5; B7Z6M9; B7Z9Q2; F5H383; hsa:4088; O09064; O09144; O14510; O35273; P84022; Q92940; Q93002; Q9GKR4"	"Ub-specific processing proteases; Formation of axial mesoderm; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Signaling by NODAL; FOXO-mediated transcription of cell cycle genes; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Germ layer formation at gastrulation; Formation of definitive endoderm; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; RUNX3 regulates BCL2L11 (BIM) transcription; Signaling by Activin; SMAD2/3 Phosphorylation Motif Mutants in Cancer; TGFBR1 KD Mutants in Cancer; Interleukin-37 signaling; RUNX3 regulates CDKN1A transcription; NOTCH4 Intracellular Domain Regulates Transcription; SMAD4 MH2 Domain Mutants in Cancer; SMAD2/3 MH2 Domain Mutants in Cancer"	"Androgen receptor signaling pathway; Cell cycle; AGE/RAGE pathway; Adipogenesis; Endoderm differentiation; Mesodermal commitment pathway; Extracellular vesicle-mediated signaling in recipient cells; Mesodermal commitment pathway; Ovarian infertility; Hepatitis C and hepatocellular carcinoma; Hypothesized pathways in pathogenesis of cardiovascular disease; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Canonical and non-canonical TGF-B signaling; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Pancreatic adenocarcinoma pathway; Neovascularisation processes; Vitamin D in inflammatory diseases; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Hepatitis B infection; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; Angiotensin II receptor type 1 pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Progeria-associated lipodystrophy; GDNF signaling; Urotensin-II-mediated signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; DNA damage response (only ATM dependent)"	"55"	"0"	"24.7"	"15.9"	"27.3"	"16.8"	"22.0"	"22.2"	"70.0"	"7.6"	"676.4"	"645.3"	"1017.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08237"	"ATP-dependent 6-phosphofructokinase, muscle type OS=Homo sapiens OX=9606 GN=PFKM PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"780"	"85.1"	"7.99"	"718.51"	"7.47"	"2"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"kinase activity;other molecular function"	"Pf00365"	"5213"	"ENSG00000152556"	"PFKM"	"hsa:5213; J3KNX3; P08237; Q16814; Q16815; Q6ZTT1"	"Glycolysis"	"Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Insulin signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"6"	"0"	"17.2"	"11.8"	"22.0"	"26.4"	"21.5"	"20.0"	"41.0"	"2.7"	"358.7"	"346.9"	"646.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZM3"	"Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1697"	"193.3"	"8.12"	"690.47"	"7.46"	"2"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00168, Pf00621, Pf07653, Pf12763, Pf14604, Pf16652"	"50618"	"ENSG00000198399"	"ITSN2"	"hsa:50618; O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9NZM3; Q9ULG4"	"Cargo recognition for clathrin-mediated endocytosis; RHOU GTPase cycle"	""	"3"	"0"	"3.9"	"3.2"	"4.8"	"4.8"	"10.5"	"10.0"	"30.6"	"5.4"	"236.4"	"198.7"	"301.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3T9"	"Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4"	"0.000"	""	"6"	"4"	"7"	"4"	"749"	"84.9"	"5.62"	"1173.96"	"7.46"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03715"	"26155"	"ENSG00000188976"	"NOC2L"	"hsa:26155; Q5SVA3; Q9BTN6; Q9Y3T9"	"Regulation of TP53 Activity through Phosphorylation"	"1p36 copy number variation syndrome"	"2"	"0"	"117.6"	"79.1"	"101.3"	"100.3"	"94.9"	"96.8"	"154.0"	"7.7"	"514.3"	"509.2"	"950.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12899"	"Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"539"	"62.1"	"5.03"	"950.26"	"7.45"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"7726"	"ENSG00000137313; ENSG00000226060; ENSG00000228881; ENSG00000230230; ENSG00000231002; ENSG00000231641; ENSG00000234046; ENSG00000234127"	"TRIM26"	"A6NG96; hsa:7726; Q12899; Q5SRL2"	"Interferon gamma signaling"	""	"1"	"0"	"10.8"	"9.4"	"14.4"	"9.6"	"9.6"	"13.7"	"39.9"	"0.5"	"125.3"	"138.5"	"234.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6W5"	"Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"1"	"498"	"54.3"	"5.53"	"777.15"	"7.40"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10163"	"ENSG00000158195"	"WASF2"	"B4DZN0; hsa:10163; O60794; Q9UDY7; Q9Y6W5"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	"Regulation of actin cytoskeleton"	"8"	"0"	"7.2"	"4.7"	"5.7"	"6.5"	"8.4"	"8.3"	"9.1"	"0.0"	"252.6"	"258.5"	"528.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26196"	"Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2"	"0.000"	""	"4"	"2"	"5"	"2"	"483"	"54.4"	"8.66"	"722.26"	"7.39"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1656"	"ENSG00000110367"	"DDX6"	"hsa:1656; P26196; Q5D048"	"mRNA decay by 5' to 3' exoribonuclease"	""	"1"	"0"	"86.1"	"64.2"	"84.0"	"80.5"	"77.9"	"76.3"	"176.8"	"0.5"	"663.2"	"655.4"	"1453.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G46"	"tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS3L PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"650"	"72.5"	"8.05"	"621.57"	"7.39"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf01207, Pf18044"	"56931"	"ENSG00000141994"	"DUS3L"	"hsa:56931; Q96G46; Q96HM5; Q9BSU4; Q9H877; Q9NPR1"	""	""	"0"	"0"	"39.6"	"29.1"	"44.2"	"33.2"	"30.1"	"27.7"	"53.9"	"2.2"	"137.2"	"122.9"	"232.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U06"	"Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"1"	"439"	"48.7"	"9.85"	"807.69"	"7.38"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf15519"	"55147"	"ENSG00000100461"	"RBM23"	"D3DS32; hsa:55147; Q86U06; Q8ND16; Q8TB88; Q8WY40; Q9BUJ1; Q9NVV7"	""	""	"0"	"0"	"5.0"	"2.3"	"0.0"	"2.0"	"0.0"	"1.9"	"3.7"	"0.0"	"34.5"	"34.1"	"69.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULR0"	"Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3"	"0.000"	""	"11"	"2"	"4"	"2"	"285"	"33.0"	"5.17"	"753.50"	"7.36"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf06246"	"100534599; 57461"	"ENSG00000240682"	"ISY1"	"hsa:100534599; hsa:57461; Q96IL2; Q9BT05; Q9ULR0"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Major Pathway"	""	"5"	"0"	"54.5"	"47.1"	"52.0"	"66.8"	"44.8"	"50.2"	"92.6"	"0.0"	"446.6"	"448.3"	"1038.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96LT9"	"RNA-binding region-containing protein 3 OS=Homo sapiens OX=9606 GN=RNPC3 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"517"	"58.5"	"7.72"	"450.67"	"7.32"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"55599"	"ENSG00000185946"	"RNPC3"	"A8K1C9; D3DT74; hsa:55599; Q5TZ87; Q96FK7; Q96JI8; Q96LT9; Q9NSU7; Q9NXX2"	"mRNA Splicing - Minor Pathway"	""	"1"	"0"	"17.0"	"16.5"	"18.0"	"11.8"	"10.6"	"13.7"	"30.2"	"1.9"	"109.4"	"110.6"	"185.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46779"	"60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3"	"0.000"	""	"16"	"3"	"6"	"3"	"137"	"15.7"	"12.02"	"850.64"	"7.29"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01778"	"6158"	"ENSG00000108107"	"RPL28"	"B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; hsa:6158; P46779; Q6IAY0; Q96FX1; Q9BWQ0"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"89.9"	"64.4"	"101.0"	"87.5"	"84.0"	"89.7"	"490.5"	"0.0"	"1867.3"	"1951.6"	"3230.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96F85"	"CB1 cannabinoid receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=CNRIP1 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"164"	"18.6"	"7.94"	""	"7.27"	""	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf15043"	"25927"	"ENSG00000119865"	"CNRIP1"	"B2R4D0; hsa:25927; Q49AN4; Q96F85; Q9UFZ0"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"5.7"	"12.0"	"17.1"	"40.9"	"0.0"	"217.4"	"200.8"	"338.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92890"	"Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens OX=9606 GN=UFD1 PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"307"	"34.5"	"6.70"	"839.55"	"7.27"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03152"	"7353"	"ENSG00000070010"	"UFD1"	"A8MW31; hsa:7353; Q92890; Q9Y5N0"	"Ub-specific processing proteases; Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"22q11.2 copy number variation syndrome"	"5"	"0"	"66.9"	"47.3"	"62.5"	"60.7"	"64.7"	"66.8"	"96.8"	"0.0"	"1095.0"	"1221.2"	"2176.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10586"	"Receptor-type tyrosine-protein phosphatase F OS=Homo sapiens OX=9606 GN=PTPRF PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1907"	"212.7"	"6.30"	"349.71"	"7.27"	"1"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00041, Pf00102, Pf07679"	"5792"	"ENSG00000142949"	"PTPRF"	"D3DPX6; D3DPX7; hsa:5792; P10586; Q5T021; Q5T022; Q5W9G2; Q86WS0"	"Insulin receptor recycling; Synaptic adhesion-like molecules; Receptor-type tyrosine-protein phosphatases"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Insulin signaling"	"5"	"0"	"3.4"	"0.0"	"5.6"	"5.6"	"0.0"	"4.4"	"5.1"	"2.1"	"122.6"	"125.8"	"242.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05026"	"Sodium/potassium-transporting ATPase subunit beta-1 OS=Homo sapiens OX=9606 GN=ATP1B1 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"303"	"35.0"	"8.53"	"703.74"	"7.26"	"2"	"2"	"cell adhesion;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf00287"	"481"	"ENSG00000143153"	"ATP1B1"	"hsa:481; P05026; Q5TGZ3"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases; Basigin interactions"	"Proximal tubule transport; Calcium regulation in cardiac cells"	"6"	"0"	"8.7"	"8.7"	"13.6"	"14.0"	"11.7"	"11.5"	"21.6"	"0.1"	"136.0"	"162.5"	"270.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TJ2"	"Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"420"	"48.4"	"7.83"	"725.92"	"7.26"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249"	"93624"	"ENSG00000173011"	"TADA2B"	"A0AUJ8; A4QMR7; B3KSN0; B3KU86; hsa:93624; Q6MZG9; Q86TJ2"	"HATs acetylate histones; Ub-specific processing proteases"	""	"2"	"0"	"19.5"	"11.3"	"15.4"	"16.1"	"17.5"	"18.2"	"42.6"	"3.3"	"532.1"	"537.9"	"1041.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49840"	"Glycogen synthase kinase-3 alpha OS=Homo sapiens OX=9606 GN=GSK3A PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"483"	"50.9"	"8.75"	"780.43"	"7.22"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"2931"	"ENSG00000105723"	"GSK3A"	"hsa:2931; O14959; P49840"	"Constitutive Signaling by AKT1 E17K in Cancer; XBP1(S) activates chaperone genes; AKT phosphorylates targets in the cytosol; Suppression of apoptosis; Maturation of nucleoprotein; Maturation of nucleoprotein"	"IL-5 signaling pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Leptin signaling pathway; B cell receptor signaling pathway; T cell receptor and co-stimulatory signaling; Wnt signaling pathway; Regulation of apoptosis by parathyroid hormone-related protein; Angiopoietin-like protein 8 regulatory pathway; Nonalcoholic fatty liver disease; Insulin signaling; Glycogen synthesis and degradation"	"17"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62306"	"Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1"	"0.000"	""	"15"	"1"	"4"	"1"	"86"	"9.7"	"4.67"	"904.88"	"7.20"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6636"	"ENSG00000139343"	"SNRPF"	"A2VCR2; B2R498; hsa:6636; P62306; Q15356; Q6IBQ1; Q6P4I0"	"snRNP Assembly; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"mRNA processing"	"8"	"0"	"31.0"	"19.7"	"33.4"	"28.6"	"24.7"	"34.2"	"62.9"	"1.6"	"324.1"	"296.3"	"881.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYG3"	"MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1"	"0.000"	""	"6"	"1"	"4"	"1"	"293"	"34.2"	"9.88"	"775.68"	"7.20"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12196"	"84365"	"ENSG00000155438"	"NIFK"	"A8K788; hsa:84365; Q8TB66; Q96ED4; Q9BYG3"	""	""	"0"	"0"	"13.6"	"11.4"	"14.0"	"12.5"	"15.2"	"8.1"	"24.9"	"0.0"	"167.9"	"159.6"	"343.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5HYJ3"	"Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3"	"0.000"	""	"8"	"3"	"4"	"1"	"339"	"38.7"	"9.25"	"617.22"	"7.16"	"2"	"2"	""	"nucleus"	""	"Pf16046"	"143684"	"ENSG00000077458"	"FAM76B"	"B2R9C2; hsa:143684; Q5HYJ3; Q6PIU3; Q8TC53"	""	""	"0"	"0"	"9.7"	"6.1"	"15.5"	"9.9"	"10.2"	"10.7"	"22.8"	"0.0"	"147.0"	"151.9"	"252.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVV4"	"Poly(A) RNA polymerase, mitochondrial OS=Homo sapiens OX=9606 GN=MTPAP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"582"	"66.1"	"9.04"	"588.57"	"7.12"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf03828, Pf17797"	"55149"	"ENSG00000107951"	"MTPAP"	"D3DRX0; hsa:55149; Q659E3; Q6P7E5; Q9HA74; Q9NVV4"	""	""	"0"	"0"	"8.9"	"5.9"	"12.2"	"14.4"	"8.8"	"7.3"	"32.9"	"0.0"	"271.8"	"275.0"	"602.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15651"	"High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2"	"0.000"	""	"42"	"3"	"5"	"3"	"99"	"10.7"	"9.66"	"932.22"	"7.11"	"3"	"2"	"cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"9324"	"ENSG00000118418"	"HMGN3"	"B2RD37; hsa:9324; Q15651; Q5HYD3; Q7RTT0; Q969M5; Q9BZT7"	""	""	"0"	"0"	"95.6"	"64.7"	"102.0"	"103.6"	"81.5"	"95.9"	"189.0"	"10.4"	"1091.8"	"1067.4"	"2307.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2W6"	"39S ribosomal protein L46, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL46 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"279"	"31.7"	"7.05"	"391.17"	"7.11"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf11788"	"26589"	"ENSG00000259494"	"MRPL46"	"B2RD75; hsa:26589; Q9H2W6; Q9HBU8"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"92.5"	"64.0"	"97.1"	"88.1"	"89.5"	"88.8"	"150.9"	"4.7"	"1275.5"	"1317.4"	"3070.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVC0"	"RNA polymerase-associated protein LEO1 OS=Homo sapiens OX=9606 GN=LEO1 PE=1 SV=1"	"0.000"	""	"6"	"3"	"4"	"3"	"666"	"75.4"	"4.51"	"892.26"	"7.11"	"2"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf04004"	"123169"	"ENSG00000166477"	"LEO1"	"hsa:123169; Q8WVC0; Q96N99"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex"	"Endoderm differentiation"	"6"	"0"	"191.2"	"148.3"	"189.7"	"190.0"	"173.8"	"184.1"	"328.8"	"3.2"	"790.8"	"752.4"	"1424.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NC96"	"Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2"	"0.000"	""	"15"	"4"	"6"	"3"	"275"	"29.7"	"6.80"	"1295.38"	"7.09"	"4"	"2"	"transport"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf07933"	"25977"	"ENSG00000089818"	"NECAP1"	"hsa:25977; Q2NL73; Q5XG95; Q6NWY6; Q8N153; Q8NC96; Q8NCB0; Q9BU52; Q9Y407"	"Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis"	""	"3"	"1"	"67.9"	"51.9"	"72.8"	"67.1"	"74.2"	"130.6"	"475.7"	"1.0"	"2825.9"	"2694.6"	"3620.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPB8"	"Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens OX=9606 GN=GPCPD1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"672"	"76.0"	"5.53"	"678.53"	"7.09"	"2"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00686, Pf03009"	"56261"	"ENSG00000125772"	"GPCPD1"	"D3DW06; hsa:56261; Q9BQL8; Q9NPB8; Q9NUX0"	"Hydrolysis of LPC; Hydrolysis of LPE"	""	"2"	"0"	"9.0"	"0.0"	"12.0"	"8.9"	"9.0"	"8.7"	"19.2"	"5.3"	"311.1"	"331.1"	"714.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29084"	"Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"291"	"33.0"	"9.66"	"751.63"	"7.08"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02186, Pf18121"	"2961"	"ENSG00000197265"	"GTF2E2"	"D3DSV2; hsa:2961; P29084; Q9H2B9"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"Eukaryotic transcription initiation"	"10"	"0"	"58.7"	"49.8"	"60.5"	"44.2"	"65.6"	"58.2"	"135.9"	"0.0"	"724.3"	"778.6"	"1671.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR50"	"Translation initiation factor eIF-2B subunit gamma OS=Homo sapiens OX=9606 GN=EIF2B3 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"452"	"50.2"	"6.47"	"398.66"	"7.08"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00483"	"8891"	"ENSG00000070785"	"EIF2B3"	"B2RBH8; D3DPZ2; hsa:8891; Q5QP89; Q5QP90; Q8NDB5; Q8WV57; Q9H850; Q9NR50"	"Recycling of eIF2:GDP"	"Translation factors; Primary ovarian insufficiency"	"3"	"0"	"24.8"	"19.0"	"28.9"	"26.7"	"22.3"	"26.3"	"49.3"	"1.3"	"711.8"	"768.4"	"1736.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99567"	"Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"741"	"83.5"	"5.69"	"793.26"	"7.08"	"2"	"2"	"cell cycle OR cell proliferation;other metabolic processes;transport"	"cytosol;nucleus"	"other molecular function"	"Pf10168"	"4927"	"ENSG00000108559"	"NUP88"	"D3DTM2; hsa:4927; Q99567; Q9BWE5"	"HCMV Early Events; ISG15 antiviral mechanism; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; HCMV Late Events; Regulation of HSF1-mediated heat shock response; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; Nuclear Pore Complex (NPC) Disassembly; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"Ciliary landscape"	"29"	"0"	"59.6"	"43.1"	"60.3"	"51.2"	"46.8"	"43.4"	"101.2"	"0.6"	"713.3"	"798.0"	"1496.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B2"	"Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1"	"0.000"	""	"12"	"2"	"4"	"2"	"195"	"21.4"	"8.24"	"849.92"	"7.07"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity"	"Pf10447, Pf14382"	"51013"	"ENSG00000171311"	"EXOSC1"	"B2R9B3; hsa:51013; Q5JTH3; Q9Y3B2"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"10.7"	"9.4"	"17.8"	"15.9"	"14.4"	"12.6"	"38.7"	"0.5"	"380.1"	"368.8"	"814.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07711"	"Cathepsin L1 OS=Homo sapiens OX=9606 GN=CTSL PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"1"	"333"	"37.5"	"5.45"	"683.11"	"7.06"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1514"	"ENSG00000135047"	"CTSL"	"hsa:1514; P07711; Q6IAV1; Q96QJ0"	"MHC class II antigen presentation; Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Attachment and Entry; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Attachment and Entry; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway"	"Primary focal segmental glomerulosclerosis (FSGS); Ebola virus infection in host; Mitochondrial immune response to SARS-CoV-2"	"12"	"0"	"6.8"	"5.4"	"8.7"	"8.0"	"6.9"	"14.2"	"31.2"	"0.0"	"407.2"	"344.6"	"768.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60341"	"Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"852"	"92.8"	"6.52"	"380.18"	"7.05"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01593, Pf04433"	"23028"	"ENSG00000004487"	"KDM1A"	"A8MWP9; hsa:23028; O60341; Q5TH94; Q5TH95; Q86VT7; Q8IXK4; Q8NDP6; Q8TAZ3; Q96AW4"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"	"Androgen receptor signaling pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Thermogenesis; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Neurogenesis regulation in the olfactory epithelium"	"14"	"0"	"41.1"	"26.0"	"40.0"	"36.7"	"34.0"	"38.3"	"75.9"	"2.1"	"547.1"	"589.8"	"1405.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q02750"	"Dual specificity mitogen-activated protein kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP2K1 PE=1 SV=2"	""	""	"5"	"2"	"2"	"2"	"393"	"43.4"	"6.62"	""	"7.04"	""	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"5604"	"ENSG00000169032"	"MAP2K1"	"hsa:5604; Q02750"	"Signaling by BRAF and RAF1 fusions; Uptake and function of anthrax toxins; Signal transduction by L1; RAF activation; MAP3K8 (TPL2)-dependent MAPK1/3 activation; MAPK3 (ERK1) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Negative feedback regulation of MAPK pathway; Signaling by MAP2K mutants"	"IL-5 signaling pathway; Osteopontin signaling; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Aryl hydrocarbon receptor pathway; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; IL6 signaling pathway; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ethanol metabolism production of ROS by CYP2E1; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; Pleural mesothelioma; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling; Serotonin receptor 4/6/7 and NR3C signaling; Toll-like receptor signaling pathway"	"96"	"0"	"3.6"	"3.3"	"6.2"	"6.6"	"6.4"	"6.5"	"20.2"	"4.9"	"394.7"	"432.7"	"1298.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51397"	"Death-associated protein 1 OS=Homo sapiens OX=9606 GN=DAP PE=1 SV=3"	""	""	"25"	"1"	"1"	"1"	"102"	"11.2"	"9.32"	""	"7.04"	""	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	""	"other molecular function"	"Pf15228"	"1611"	"ENSG00000112977"	"DAP"	"hsa:1611; P51397; Q6FGC3; Q9BUC9"	""	""	"0"	"0"	"34.0"	"24.9"	"38.6"	"29.2"	"36.0"	"46.3"	"49.9"	"0.0"	"273.9"	"260.6"	"667.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02224"	"Centromere-associated protein E OS=Homo sapiens OX=9606 GN=CENPE PE=1 SV=2"	"0.000"	""	"1"	"3"	"5"	"2"	"2701"	"316.2"	"5.64"	"517.71"	"7.04"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"1062"	"ENSG00000138778"	"CENPE"	"A6NKY9; A8K2U7; hsa:1062; Q02224; Q4LE75"	"RHO GTPases Activate Formins; COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Regulation of sister chromatid separation at the metaphase-anaphase transition"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3G5"	"Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"476"	"54.1"	"5.62"	"695.53"	"7.03"	"2"	"2"	"protein metabolism"	""	"other molecular function"	"Pf00450"	"54504"	"ENSG00000106066"	"CPVL"	"A4D1A4; hsa:54504; Q6UX20; Q8NBL7; Q96AR7; Q9H3G5; Q9HB41"	""	""	"0"	"0"	"14.7"	"15.9"	"30.4"	"15.8"	"11.8"	"15.9"	"35.2"	"0.0"	"1282.6"	"1184.7"	"3041.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92558"	"Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"559"	"61.6"	"6.46"	"968.10"	"7.02"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"8936"	"ENSG00000112290"	"WASF1"	"E1P5F2; hsa:8936; Q5SZK7; Q92558"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"VEGFA-VEGFR2 signaling; Regulation of actin cytoskeleton"	"8"	"0"	"30.0"	"33.7"	"38.2"	"35.2"	"31.6"	"38.2"	"67.0"	"1.0"	"362.9"	"336.2"	"628.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07065"	"Cytoskeleton-associated protein 4 OS=Homo sapiens OX=9606 GN=CKAP4 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"602"	"66.0"	"5.92"	"616.95"	"7.02"	"2"	"2"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	""	""	"10970"	"ENSG00000136026"	"CKAP4"	"hsa:10970; Q07065; Q504S5; Q53ES6"	"Neutrophil degranulation; RND2 GTPase cycle; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RND3 GTPase cycle; Surfactant metabolism"	""	"6"	"0"	"8.0"	"8.3"	"10.8"	"12.8"	"8.2"	"14.9"	"33.6"	"0.0"	"116.9"	"109.3"	"197.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17677"	"Neuromodulin OS=Homo sapiens OX=9606 GN=GAP43 PE=1 SV=1"	"0.000"	""	"8"	"1"	"3"	"1"	"238"	"24.8"	"4.72"	"343.25"	"7.01"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00612, Pf06614, Pf10580"	"2596"	"ENSG00000172020"	"GAP43"	"A8K0Y4; hsa:2596; P17677"	"L1CAM interactions"	"Glial cell differentiation; Spinal cord injury"	"3"	"0"	"6.5"	"2.2"	"7.0"	"6.0"	"3.8"	"6.8"	"3.6"	"2.4"	"89.6"	"84.4"	"217.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15050"	"Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2"	"0.000"	""	"15"	"3"	"5"	"3"	"365"	"41.2"	"10.70"	"1079.36"	"7.01"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04939"	"23212"	"ENSG00000179041"	"RRS1"	"hsa:23212; Q15050; Q9BUX8"	""	""	"0"	"0"	"115.2"	"95.3"	"126.1"	"105.0"	"104.0"	"110.9"	"339.7"	"0.0"	"899.7"	"867.5"	"1794.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WTT2"	"Nucleolar complex protein 3 homolog OS=Homo sapiens OX=9606 GN=NOC3L PE=1 SV=1"	"0.000"	""	"1"	"1"	"4"	"1"	"800"	"92.5"	"9.17"	"534.11"	"7.01"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf03914, Pf07540"	"64318"	"ENSG00000173145"	"NOC3L"	"hsa:64318; Q8WTT2; Q9H5M6; Q9H9D8"	""	""	"0"	"0"	"6.3"	"5.8"	"6.5"	"11.1"	"11.6"	"5.0"	"35.9"	"0.4"	"191.5"	"202.8"	"384.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14802"	"DNA-directed RNA polymerase III subunit RPC1 OS=Homo sapiens OX=9606 GN=POLR3A PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"1"	"1390"	"155.5"	"8.48"	"709.29"	"6.99"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"11128"	"ENSG00000148606"	"POLR3A"	"hsa:11128; O14802; Q8IW34; Q8TCW5"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway"	"9"	"0"	"8.5"	"2.2"	"7.8"	"7.7"	"9.1"	"5.8"	"14.5"	"1.2"	"69.5"	"74.6"	"125.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75663"	"TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2"	"0.000"	""	"12"	"2"	"3"	"2"	"272"	"31.4"	"5.91"	"434.92"	"6.99"	"1"	"2"	"stress response;signal transduction;other biological processes"	"cytosol"	""	"Pf04176"	"261726"	"ENSG00000143155"	"TIPRL"	"B2R8V3; hsa:261726; O75663; Q5HYB2; Q8IZ86"	""	"Ciliary landscape"	"1"	"0"	"104.6"	"91.5"	"107.2"	"113.6"	"96.8"	"83.7"	"99.4"	"0.0"	"323.7"	"319.6"	"518.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14676"	"Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"2089"	"226.5"	"5.47"	"713.02"	"6.99"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00498, Pf16770"	"9656"	"ENSG00000137337; ENSG00000206481; ENSG00000224587; ENSG00000225589; ENSG00000228575; ENSG00000231135; ENSG00000234012; ENSG00000237095"	"MDC1"	"A2AB04; A2BF04; A2RRA8; A7YY86; B0S8A2; hsa:9656; Q0EFC2; Q14676; Q2L6H7; Q2TAZ4; Q5JP55; Q5JP56; Q5ST83; Q68CQ3; Q86Z06; Q96QC2"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; SUMOylation of DNA damage response and repair proteins; TP53 Regulates Transcription of DNA Repair Genes; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"ATM signaling in development and disease ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"9"	"0"	"54.7"	"43.5"	"68.1"	"58.8"	"47.9"	"53.2"	"120.2"	"2.3"	"613.7"	"592.9"	"1195.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62847"	"40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1"	"0.000"	""	"9"	"1"	"4"	"1"	"133"	"15.4"	"10.78"	"816.55"	"6.96"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01282"	"6229"	"ENSG00000138326"	"RPS24"	"E7EPK6; hsa:6229; P16632; P62847; Q5T0P7; Q5T0P8; Q7Z3D1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"22.3"	"15.9"	"32.4"	"23.7"	"25.8"	"32.3"	"76.7"	"0.0"	"526.9"	"471.4"	"1284.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95218"	"Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2"	"0.000"	""	"11"	"3"	"5"	"3"	"330"	"37.4"	"10.01"	"567.26"	"6.96"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00641"	"9406"	"ENSG00000132485"	"ZRANB2"	"D3DQ75; hsa:9406; O95218; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63"	""	""	"0"	"0"	"276.8"	"221.2"	"253.2"	"282.2"	"235.1"	"235.8"	"502.5"	"0.0"	"1266.6"	"1246.4"	"2253.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q66LE6"	"Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform OS=Homo sapiens OX=9606 GN=PPP2R2D PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"453"	"52.0"	"6.39"	"660.67"	"6.96"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	""	"55844"	"ENSG00000175470"	"PPP2R2D"	"A8KAK0; hsa:55844; Q5SQJ2; Q66LE6; Q9P1Y7"	"MASTL Facilitates Mitotic Progression"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"3"	"0"	"8.8"	"6.3"	"20.0"	"10.0"	"13.6"	"10.3"	"19.9"	"1.5"	"104.2"	"110.3"	"256.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75955"	"Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"427"	"47.3"	"7.49"	"766.16"	"6.95"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"10211"	"ENSG00000137312; ENSG00000206379; ENSG00000206480; ENSG00000230143; ENSG00000232280"	"FLOT1"	"B4DVY7; hsa:10211; O75955; Q969J8; Q9UHW1; Q9UNV8"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; Synaptic adhesion-like molecules"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"8"	"0"	"28.7"	"21.2"	"21.5"	"23.3"	"27.9"	"32.0"	"52.1"	"6.7"	"368.1"	"365.6"	"704.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15438"	"Cytohesin-1 OS=Homo sapiens OX=9606 GN=CYTH1 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"398"	"46.4"	"5.54"	""	"6.95"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01369"	"9267"	"ENSG00000108669"	"CYTH1"	"A6NFW7; B7Z1T4; hsa:9267; Q15438; Q9P123; Q9P124"	"Intra-Golgi traffic"	"2q37 copy number variation syndrome"	"2"	"0"	"11.7"	"8.2"	"8.6"	"9.2"	"12.0"	"19.4"	"44.5"	"0.0"	"228.8"	"235.9"	"422.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07947"	"Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3"	"0.000"	""	"4"	"2"	"4"	"2"	"543"	"60.8"	"6.74"	"729.25"	"6.94"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"7525"	"ENSG00000176105"	"YES1"	"A6NLB3; D3DUH1; hsa:7525; P07947"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; Signaling by ERBB2; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling"	"Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; NRF2-ARE regulation; Gastrin signaling pathway; GDNF signaling"	"22"	"0"	"113.0"	"74.6"	"124.6"	"114.0"	"117.2"	"108.9"	"148.4"	"0.7"	"758.3"	"776.3"	"1705.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9N5"	"Protein BANP OS=Homo sapiens OX=9606 GN=BANP PE=1 SV=3"	"0.000"	""	"7"	"2"	"3"	"2"	"519"	"56.5"	"5.49"	"364.48"	"6.94"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10523"	"54971"	"ENSG00000172530"	"BANP"	"A8MU25; A8MX25; B2RCF7; B4DNJ9; F5GZM0; hsa:54971; Q8N9N5; Q96GJ7; Q9NWY1"	"Regulation of TP53 Activity through Association with Co-factors"	""	"1"	"0"	"32.1"	"23.9"	"24.8"	"29.2"	"25.1"	"24.4"	"55.1"	"0.0"	"417.5"	"415.8"	"815.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWC1"	"MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"1"	"876"	"98.4"	"9.32"	"748.12"	"6.93"	"2"	"2"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf05672"	"79649"	"ENSG00000129680"	"MAP7D3"	"A2A2J0; A6NCZ7; A6NHR4; B4DWD2; H7BY77; hsa:79649; Q5JXI5; Q5JXI6; Q6P2S1; Q8IWC1; Q9H9M8"	""	""	"0"	"1"	"56.8"	"38.0"	"52.5"	"47.7"	"34.2"	"46.2"	"480.6"	"0.0"	"723.6"	"739.0"	"1196.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5B9"	"FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1"	"0.000"	""	"3"	"3"	"5"	"3"	"1047"	"119.8"	"5.66"	"878.68"	"6.92"	"3"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00557, Pf08512, Pf08644, Pf14826"	"11198"	"ENSG00000092201"	"SUPT16H"	"hsa:11198; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0; Q9Y5B9"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation"	""	"12"	"0"	"53.3"	"48.7"	"58.8"	"46.0"	"63.9"	"52.6"	"108.2"	"1.0"	"574.6"	"570.9"	"1257.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92793"	"CREB-binding protein OS=Homo sapiens OX=9606 GN=CREBBP PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"2442"	"265.2"	"8.53"	"488.73"	"6.91"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00569, Pf02135, Pf02172, Pf06001, Pf08214, Pf09030"	"1387"	"ENSG00000005339"	"CREBBP"	"D3DUC9; hsa:1387; O00147; Q16376; Q4LE28; Q92793"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; NPAS4 regulates expression of target genes; Formation of paraxial mesoderm; Heme signaling; Formation of the beta-catenin:TCF transactivating complex; SUMOylation of transcription cofactors; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Cytoprotection by HMOX1; Pre-NOTCH Transcription and Translation; Activation of gene expression by SREBF (SREBP); NFE2L2 regulating anti-oxidant/detoxification enzymes; HATs acetylate histones; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; Notch-HLH transcription pathway; Nuclear events mediated by NFE2L2; NFE2L2 regulates pentose phosphate pathway genes; NOTCH3 Intracellular Domain Regulates Transcription; FOXO-mediated transcription of cell death genes; Regulation of FOXO transcriptional activity by acetylation; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; RORA activates gene expression; Attenuation phase; CD209 (DC-SIGN) signaling; Activation of the TFAP2 (AP-2) family of transcription factors; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation; Regulation of gene expression by Hypoxia-inducible Factor; RUNX1 regulates transcription of genes involved in differentiation of myeloid cells; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"Androgen receptor signaling pathway; Angiogenesis; TNF-alpha signaling pathway; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; IL6 signaling pathway; Pathways affected in adenoid cystic carcinoma; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Clear cell renal cell carcinoma pathways; Ebola virus infection in host; Type 2 papillary renal cell carcinoma; Ciliary landscape; Hepatitis B infection; Male infertility; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; 15q13.3 copy number variation syndrome; Urotensin-II-mediated signaling pathway; 15q11q13 copy number variation; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways"	"64"	"0"	"18.0"	"19.0"	"23.2"	"19.2"	"20.9"	"18.4"	"46.1"	"1.1"	"325.7"	"345.6"	"655.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCG8"	"Pre-mRNA-splicing factor CWC22 homolog OS=Homo sapiens OX=9606 GN=CWC22 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"908"	"105.4"	"7.03"	"878.03"	"6.91"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf02847"	"57703"	"ENSG00000163510"	"CWC22"	"hsa:57703; Q05DC2; Q4G135; Q52LF0; Q6PEX2; Q7Z6I0; Q9H5L3; Q9H6Q6; Q9HCG8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"11.7"	"9.9"	"17.2"	"15.1"	"19.3"	"9.4"	"43.2"	"0.0"	"311.5"	"303.9"	"869.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6A4"	"Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"193"	"22.8"	"9.76"	"521.58"	"6.89"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05018"	"29105"	"ENSG00000070761"	"CFAP20"	"hsa:29105; Q9Y6A4"	""	""	"0"	"0"	"21.8"	"26.0"	"15.5"	"17.7"	"15.6"	"17.5"	"49.7"	"0.6"	"233.8"	"249.8"	"561.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14314"	"Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"528"	"59.4"	"4.41"	"1265.14"	"6.89"	"3"	"2"	"protein metabolism;other metabolic processes;developmental processes;signal transduction"	"ER/Golgi;other cell component"	"other molecular function"	"Pf12999, Pf13015, Pf13202"	"5589"	"ENSG00000130175"	"PRKCSH"	"A8K318; hsa:5589; P14314; Q96BU9; Q96D06; Q9P0W9"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Advanced glycosylation endproduct receptor signaling; Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	""	"7"	"0"	"182.1"	"143.0"	"266.4"	"214.4"	"215.2"	"227.4"	"684.8"	"0.8"	"1017.6"	"979.6"	"1361.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10599"	"Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3"	"0.000"	""	"19"	"2"	"4"	"2"	"105"	"11.7"	"4.92"	"690.60"	"6.89"	"2"	"2"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085"	"7295"	"ENSG00000136810"	"TXN"	"B1ALW1; hsa:7295; O60744; P10599; Q53X69; Q96KI3; Q9UDG5"	"Detoxification of Reactive Oxygen Species; Oxidative Stress Induced Senescence; TP53 Regulates Metabolic Genes; Interconversion of nucleotide di- and triphosphates; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; Regulation of FOXO transcriptional activity by acetylation; Protein repair"	"Selenium micronutrient network; Folic acid network; Selenium micronutrient network ; Folic acid network; Selenium micronutrient network; TNF-alpha signaling pathway; Complement system; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; TAR syndrome"	"19"	"0"	"234.2"	"189.0"	"339.9"	"272.4"	"209.3"	"223.6"	"286.3"	"0.0"	"725.1"	"669.5"	"1428.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKF6"	"Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"684"	"77.4"	"5.60"	"768.75"	"6.87"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00753, Pf07521, Pf10996, Pf11718"	"51692"	"ENSG00000119203"	"CPSF3"	"hsa:51692; O14769; Q53RS2; Q96F36; Q9UKF6"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"6"	"0"	"5.5"	"4.8"	"13.0"	"12.0"	"9.4"	"10.4"	"19.4"	"0.0"	"345.6"	"395.9"	"911.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6SPF0"	"Atherin OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1"	"0.000"	""	"6"	"3"	"5"	"3"	"538"	"56.0"	"7.58"	"765.02"	"6.86"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"other molecular function"	"Pf00536"	"90378"	"ENSG00000288488"	"SAMD1"	"hsa:90378; Q6P0R3; Q6PIS7; Q6SPF0; Q96IM4"	""	""	"0"	"0"	"35.2"	"19.0"	"25.2"	"23.9"	"21.9"	"30.2"	"45.9"	"0.5"	"252.4"	"240.0"	"505.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14406"	"Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1"	"0.000"	""	"28"	"2"	"4"	"2"	"83"	"9.4"	"9.76"	"768.04"	"6.84"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02238"	"1347"	"ENSG00000112695"	"COX7A2"	"B2R5E1; hsa:1347; P14406; Q3MIH5; Q5TF59; Q6FGI2"	""	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	"3"	"0"	"24.2"	"18.5"	"25.6"	"20.2"	"21.0"	"27.1"	"43.9"	"0.0"	"748.9"	"802.6"	"1719.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99961"	"Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1"	""	""	"6"	"2"	"2"	"2"	"368"	"41.5"	"5.43"	""	"6.84"	""	"2"	"cell organization and biogenesis;transport;developmental processes;signal transduction"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6455"	"ENSG00000141985"	"SH3GL1"	"B4DRA1; E7EVZ4; hsa:6455; M0QZV5; Q99668; Q99961"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"Fragile X syndrome"	"6"	"0"	"19.3"	"15.5"	"25.3"	"20.2"	"21.1"	"20.2"	"46.9"	"0.0"	"757.2"	"800.1"	"2624.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5H9R7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"873"	"97.6"	"4.60"	"311.21"	"6.84"	"1"	"2"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"55291"	"ENSG00000110075"	"PPP6R3"	"hsa:55291; Q3B7I1; Q3I4Y0; Q3KR35; Q5H9R7; Q68CR3; Q7L4R8; Q8N3B2; Q96MB2; Q9H2K5; Q9H2K6; Q9HCL4; Q9NUY3"	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	""	"2"	"0"	"76.9"	"66.1"	"91.1"	"98.7"	"101.6"	"54.5"	"184.2"	"0.0"	"928.2"	"972.5"	"1634.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WXA9"	"Splicing regulatory glutamine/lysine-rich protein 1 OS=Homo sapiens OX=9606 GN=SREK1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"508"	"59.3"	"10.39"	""	"6.81"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"140890"	"ENSG00000153914"	"SREK1"	"A4FTW3; hsa:140890; Q2M1J0; Q86X37; Q8WXA9"	""	"mRNA processing"	"1"	"0"	"6.5"	"6.6"	"7.0"	"7.2"	"6.8"	"9.4"	"13.2"	"1.6"	"202.4"	"212.8"	"583.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49642"	"DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"420"	"49.9"	"8.21"	"737.80"	"6.80"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01896"	"5557"	"ENSG00000198056"	"PRIM1"	"hsa:5557; P49642"	"Activation of the pre-replicative complex; Removal of the Flap Intermediate; Polymerase switching on the C-strand of the telomere; Polymerase switching; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Telomere C-strand synthesis initiation; DNA replication initiation"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"13"	"0"	"26.8"	"16.9"	"25.4"	"24.7"	"22.9"	"21.7"	"56.4"	"8.9"	"497.0"	"489.4"	"984.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13617"	"Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"1"	"745"	"86.9"	"6.92"	"754.18"	"6.77"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8453"	"ENSG00000108094"	"CUL2"	"B3KT95; B7Z6K8; D3DRY6; G3V1S2; hsa:8453; O00200; Q13617; Q5T2B6; Q9UNF9"	"Regulation of expression of SLITs and ROBOs; Neddylation; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"6"	"0"	"9.8"	"5.3"	"10.7"	"13.3"	"14.1"	"13.8"	"21.6"	"3.3"	"171.4"	"173.3"	"348.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NF91"	"Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4"	"0.000"	""	"0"	"3"	"6"	"1"	"8797"	"1010.5"	"5.53"	"676.77"	"6.76"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23345"	"ENSG00000131018"	"SYNE1"	"B3W695; E7EQI5; H0Y4C0; hsa:23345; O94890; Q3ZCV0; Q5JV19; Q5JV22; Q8N9P7; Q8NF91; Q8TCP1; Q8WWW6; Q8WWW7; Q8WXF6; Q96N17; Q9C0A7; Q9H525; Q9H526; Q9NS36; Q9NU50; Q9UJ06; Q9UJ07; Q9ULF8"	"Meiotic synapsis"	"Envelope proteins and their potential roles in EDMD physiopathology"	"2"	"0"	"10.1"	"6.6"	"11.0"	"10.2"	"11.1"	"6.7"	"19.2"	"0.0"	"268.3"	"275.5"	"557.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ69"	"ADP-ribose glycohydrolase MACROD1 OS=Homo sapiens OX=9606 GN=MACROD1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"325"	"35.5"	"9.51"	"695.17"	"6.74"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf01661"	"28992"	"ENSG00000133315"	"MACROD1"	"hsa:28992; Q9BQ69; Q9UH96"	""	""	"0"	"0"	"46.0"	"34.5"	"58.9"	"46.3"	"47.8"	"46.4"	"84.2"	"2.8"	"742.4"	"717.8"	"1215.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTN6"	"STE20-related kinase adapter protein alpha OS=Homo sapiens OX=9606 GN=STRADA PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"431"	"48.3"	"6.48"	"783.48"	"6.74"	"2"	"2"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00069"	"92335"	"ENSG00000266173"	"STRADA"	"B4DDE3; B4DW17; hsa:92335; J3KTC9; Q5JPI2; Q7RTN6; Q7Z4K9; Q8NC31; Q8NCF1; Q9H272"	"Energy dependent regulation of mTOR by LKB1-AMPK"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"3"	"0"	"11.7"	"11.0"	"18.1"	"19.5"	"21.4"	"20.5"	"47.4"	"3.1"	"416.8"	"409.1"	"641.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5T6C5"	"Ataxin-7-like protein 2 OS=Homo sapiens OX=9606 GN=ATXN7L2 PE=1 SV=1"	""	""	"3"	"2"	"2"	"2"	"722"	"77.1"	"9.23"	""	"6.73"	""	"2"	""	""	""	"Pf08313"	"127002"	"ENSG00000162650"	"ATXN7L2"	"hsa:127002; Q5T6C5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P46821"	"Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2"	""	""	"1"	"2"	"2"	"1"	"2468"	"270.5"	"4.81"	""	"6.72"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00414"	"4131"	"ENSG00000131711"	"MAP1B"	"A2BDK5; hsa:4131; P46821"	""	"Microtubule cytoskeleton regulation; Fragile X syndrome; Neurogenesis regulation in the olfactory epithelium"	"3"	"0"	"4.3"	"2.7"	"7.1"	"7.2"	"5.7"	"7.1"	"9.7"	"2.4"	"92.8"	"91.4"	"249.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCS7"	"Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"855"	"99.9"	"6.23"	"507.66"	"6.72"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes"	"nucleus;other cell component"	""	"Pf13181"	"56949"	"ENSG00000076924"	"XAB2"	"hsa:56949; Q8TET6; Q96HB0; Q96IW0; Q9HCS7; Q9NRG6; Q9ULP3"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"Rett syndrome causing genes; Nucleotide excision repair in xeroderma pigmentosum"	"7"	"0"	"33.1"	"27.9"	"42.1"	"32.3"	"28.6"	"30.0"	"66.3"	"0.0"	"223.8"	"203.0"	"399.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14976"	"Cyclin-G-associated kinase OS=Homo sapiens OX=9606 GN=GAK PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1311"	"143.1"	"5.73"	"523.81"	"6.71"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf10409"	"2580"	"ENSG00000178950"	"GAK"	"hsa:2580; O14976; Q5U4P5; Q9BVY6"	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis"	""	"2"	"0"	"0.0"	"0.0"	"3.2"	"3.6"	"0.0"	"0.0"	"6.0"	"0.0"	"41.3"	"42.3"	"62.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT78"	"COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"406"	"46.2"	"5.83"	"660.02"	"6.70"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18420"	"51138"	"ENSG00000138663"	"COPS4"	"B3KN88; B3KST5; hsa:51138; Q561W7; Q9BT78; Q9NW31; Q9Y677"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; RHOBTB1 GTPase cycle"	"Ciliary landscape"	"6"	"0"	"2.2"	"2.8"	"2.9"	"3.1"	"2.3"	"0.0"	"15.6"	"2.2"	"176.2"	"265.7"	"446.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAU5"	"Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1272"	"147.7"	"5.69"	"694.96"	"6.69"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf04050"	"26019"	"ENSG00000151461"	"UPF2"	"A6NLJ5; D3DRS0; hsa:26019; Q14BM1; Q5W0J4; Q8N8U1; Q9H1J2; Q9HAU5; Q9NWL1; Q9P2D9; Q9Y4M9"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"2"	"0"	"19.9"	"21.1"	"26.9"	"28.4"	"23.7"	"31.9"	"80.2"	"0.0"	"354.4"	"393.7"	"705.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14669"	"E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12 PE=1 SV=1"	"0.000"	""	"2"	"3"	"4"	"3"	"1992"	"220.3"	"8.48"	"475.74"	"6.69"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00632"	"9320"	"ENSG00000153827"	"TRIP12"	"D4HL82; hsa:9320; Q14669; Q14CA3; Q14CF1; Q15644; Q53R87; Q53TE7"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"12.6"	"7.7"	"15.0"	"14.8"	"12.6"	"11.1"	"24.2"	"0.0"	"198.5"	"205.6"	"412.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYQ5"	"Microprocessor complex subunit DGCR8 OS=Homo sapiens OX=9606 GN=DGCR8 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"773"	"86.0"	"5.95"	"564.40"	"6.69"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035"	"54487"	"ENSG00000128191"	"DGCR8"	"B2R8G1; hsa:54487; Q6DCB2; Q6MZE9; Q6Y2L0; Q8WYQ5; Q96G39; Q96GP8; Q9H6L8; Q9H6T7; Q9NRW2"	"Transcriptional Regulation by MECP2; MicroRNA (miRNA) biogenesis"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"6"	"0"	"29.5"	"22.0"	"27.2"	"22.9"	"23.8"	"32.8"	"66.7"	"1.9"	"251.8"	"262.4"	"463.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CQ4"	"Digestive organ expansion factor homolog OS=Homo sapiens OX=9606 GN=DIEXF PE=1 SV=2"	"0.000"	""	"4"	"3"	"5"	"3"	"756"	"87.0"	"5.88"	"905.89"	"6.68"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf06862"	"27042"	"ENSG00000117597"	"UTP25"	"hsa:27042; O75992; Q4VY00; Q63HL9; Q68CQ4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"144.0"	"124.9"	"123.9"	"120.2"	"125.4"	"136.4"	"225.5"	"1.0"	"517.3"	"525.2"	"967.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6W2J9"	"BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1"	"0.000"	""	"2"	"3"	"4"	"3"	"1755"	"192.1"	"6.48"	"714.32"	"6.67"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12796, Pf15808, Pf16553"	"54880"	"ENSG00000183337"	"BCOR"	"D3DWB3; D3DWB4; hsa:54880; Q29RF6; Q6P4B6; Q6W2J9; Q7Z2K7; Q8TEB4; Q96DB3; Q9H232; Q9H233; Q9HCJ7; Q9NXF2"	""	"Ectoderm differentiation; Pathways affected in adenoid cystic carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"3"	"0"	"34.8"	"28.4"	"37.4"	"38.0"	"37.2"	"42.4"	"63.4"	"0.6"	"518.0"	"544.9"	"1095.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DPB6"	"DNA-directed RNA polymerases I and III subunit RPAC2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1"	"0.000"	""	"24"	"2"	"3"	"2"	"133"	"15.2"	"5.80"	"351.51"	"6.67"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"51082"	"ENSG00000186184"	"POLR1D"	"hsa:51082; P0DPB6; Q5TBX2; Q96BR3; Q9Y2S0"	""	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"4"	"0"	"16.2"	"11.6"	"18.1"	"18.3"	"14.5"	"14.6"	"23.8"	"0.0"	"550.3"	"555.4"	"993.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84101"	"Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1"	"0.000"	""	"17"	"1"	"4"	"1"	"59"	"6.9"	"10.45"	"955.35"	"6.67"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf04419"	"10169"	"ENSG00000140264"	"SERF2"	"A6NL45; B5MCG1; B9A026; hsa:10169; O75918; O88891; P84101; Q9BZH7"	""	""	"0"	"0"	"55.1"	"62.9"	"104.9"	"135.3"	"85.4"	"80.1"	"141.0"	"10.6"	"451.3"	"373.8"	"907.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZP0"	"Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4"	"0.000"	""	"6"	"2"	"4"	"2"	"508"	"55.0"	"7.06"	"586.18"	"6.67"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00018, Pf07815"	"10006"	"ENSG00000136754"	"ABI1"	"A9Z1Y6; B3KX62; B4DQ58; H7BXI6; hsa:10006; O15147; O76049; O95060; Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8IZP0; Q8TB63; Q96S81; Q9NXZ9; Q9NYB8"	"Regulation of actin dynamics for phagocytic cup formation; VEGFA-VEGFR2 Pathway; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle"	"EGF/EGFR signaling pathway"	"8"	"0"	"21.2"	"14.8"	"22.0"	"26.7"	"23.2"	"29.0"	"45.2"	"0.0"	"197.5"	"190.1"	"384.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15164"	"Transcription intermediary factor 1-alpha OS=Homo sapiens OX=9606 GN=TRIM24 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"1050"	"116.8"	"7.11"	"804.71"	"6.67"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf00628, Pf00643"	"8805"	"ENSG00000122779"	"TRIM24"	"A4D1R7; A4D1R8; hsa:8805; O15164; O95854"	"Signaling by BRAF and RAF1 fusions; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	""	"3"	"0"	"39.7"	"32.5"	"43.1"	"36.3"	"37.5"	"42.7"	"63.5"	"0.0"	"229.0"	"194.2"	"378.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75306"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"3"	"1"	"463"	"52.5"	"7.55"	"329.13"	"6.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00346"	"4720"	"ENSG00000158864"	"NDUFS2"	"D3DVG7; hsa:4720; J3KPM7; O75306; Q5VTW0; Q969P3; Q9UEV3"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"14.8"	"9.7"	"12.3"	"13.7"	"13.2"	"11.5"	"29.4"	"4.6"	"336.3"	"353.7"	"650.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YB8"	"ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"467"	"53.5"	"7.99"	"602.45"	"6.64"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf04137"	"56605"	"ENSG00000086619"	"ERO1B"	"B4DF57; hsa:56605; Q5T1H4; Q86YB8; Q8IZ11; Q9NR62"	"Insulin processing"	""	"1"	"0"	"10.8"	"10.6"	"15.7"	"18.3"	"11.7"	"18.5"	"33.5"	"1.4"	"227.8"	"220.3"	"519.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H2P0"	"Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1"	""	""	"2"	"2"	"2"	"2"	"1102"	"123.5"	"7.34"	""	"6.64"	""	"2"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00046, Pf19627"	"23394"	"ENSG00000101126"	"ADNP"	"E1P5Y2; hsa:23394; O94881; Q5BKU2; Q9H2P0; Q9UG34"	""	""	"0"	"0"	"48.0"	"26.7"	"50.5"	"52.0"	"41.0"	"28.9"	"75.7"	"3.4"	"641.8"	"629.0"	"1490.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HD33"	"39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"250"	"29.4"	"10.37"	"269.98"	"6.64"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf06984"	"57129"	"ENSG00000136522"	"MRPL47"	"hsa:57129; Q6XRG1; Q8N5D1; Q9HD33"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"3.3"	"2.6"	"1.7"	"0.0"	"5.6"	"3.5"	"2.5"	"0.0"	"33.4"	"40.1"	"83.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ67"	"Glutamate-rich WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=GRWD1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"446"	"49.4"	"4.92"	"681.30"	"6.62"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"83743"	"ENSG00000105447"	"GRWD1"	"A0MNN5; hsa:83743; Q8TF59; Q9BQ67"	""	""	"0"	"0"	"25.4"	"18.7"	"39.7"	"30.3"	"28.4"	"25.7"	"52.6"	"1.3"	"210.2"	"214.7"	"443.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75330"	"Hyaluronan mediated motility receptor OS=Homo sapiens OX=9606 GN=HMMR PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"1"	"724"	"84.0"	"5.83"	"808.01"	"6.60"	"2"	"2"	"other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf15905, Pf15908"	"3161"	"ENSG00000072571"	"HMMR"	"A8K3G2; B4E114; D3DQK9; D3DQL0; E9PCS0; hsa:3161; O75330; Q32N02; Q92767"	"AURKA Activation by TPX2; Hyaluronan uptake and degradation"	""	"2"	"0"	"12.1"	"8.8"	"10.1"	"10.7"	"10.9"	"14.3"	"19.1"	"1.9"	"171.9"	"166.9"	"329.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0L4"	"Cleavage stimulation factor subunit 2 tau variant OS=Homo sapiens OX=9606 GN=CSTF2T PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"616"	"64.4"	"7.25"	"723.44"	"6.60"	"2"	"2"	""	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf14304, Pf14327"	"23283"	"ENSG00000177613"	"CSTF2T"	"B2RAR9; hsa:23283; O75174; Q53HK6; Q7LGE8; Q8N6T1; Q9H0L4"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"mRNA processing"	"5"	"0"	"158.9"	"106.6"	"210.1"	"167.8"	"120.8"	"153.2"	"263.0"	"0.8"	"891.4"	"867.7"	"1864.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36551"	"Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"454"	"50.1"	"8.25"	"740.68"	"6.60"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01218"	"1371"	"ENSG00000080819"	"CPOX"	"A8K275; B4DSD5; hsa:1371; P36551; Q14060; Q53F08; Q8IZ45; Q96AF3"	"Heme biosynthesis"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"3"	"0"	"5.5"	"0.0"	"8.5"	"6.3"	"4.6"	"7.4"	"12.7"	"0.0"	"267.0"	"356.3"	"1683.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB21"	"Pleckstrin homology domain-containing family A member 1 OS=Homo sapiens OX=9606 GN=PLEKHA1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"404"	"45.5"	"8.56"	"719.47"	"6.52"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59338"	"ENSG00000107679"	"PLEKHA1"	"B3KQ55; D3DRE2; hsa:59338; Q9BVK0; Q9HB21"	"Synthesis of PIPs at the plasma membrane"	""	"1"	"0"	"13.3"	"8.4"	"19.7"	"13.3"	"12.9"	"19.4"	"55.0"	"0.0"	"460.4"	"424.9"	"584.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H5Z1"	"Probable ATP-dependent RNA helicase DHX35 OS=Homo sapiens OX=9606 GN=DHX35 PE=1 SV=2"	""	""	"3"	"2"	"2"	"2"	"703"	"78.9"	"8.59"	""	"6.52"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf04408, Pf07717"	"60625"	"ENSG00000101452"	"DHX35"	"A2RTX3; B4E0J0; F5GXM6; hsa:60625; Q5THR0; Q9H4H7; Q9H5Z1; Q9H6T6"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"21.6"	"9.1"	"25.2"	"17.1"	"24.1"	"18.6"	"42.8"	"0.0"	"201.7"	"215.2"	"439.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BTV4"	"Transmembrane protein 43 OS=Homo sapiens OX=9606 GN=TMEM43 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"400"	"44.8"	"8.13"	""	"6.51"	""	"1"	"cell organization and biogenesis;stress response"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf07787"	"79188"	"ENSG00000170876"	"TMEM43"	"hsa:79188; Q7L4N5; Q8NC30; Q96A63; Q96F19; Q96JX0; Q9BTV4; Q9H076"	""	"Envelope proteins and their potential roles in EDMD physiopathology"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43252"	"Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 OS=Homo sapiens OX=9606 GN=PAPSS1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"624"	"70.8"	"6.86"	"684.74"	"6.51"	"1"	"1"	"other metabolic processes;developmental processes"	"cytosol"	"kinase activity;other molecular function"	"Pf01583, Pf01747, Pf14306"	"9061"	"ENSG00000138801"	"PAPSS1"	"hsa:9061; O43252; O43841; O75332; Q6IAX6; Q96FB1; Q96TF4; Q9P1P9; Q9UE98"	"Signaling by BRAF and RAF1 fusions; Transport and synthesis of PAPS; Metabolism of ingested H2SeO4 and H2SeO3 into H2Se"	"Sulfation biotransformation reaction"	"4"	"0"	"8.4"	"8.1"	"13.6"	"11.4"	"10.3"	"7.9"	"17.4"	"0.0"	"315.6"	"359.8"	"920.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62750"	"60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1"	"0.000"	""	"22"	"4"	"6"	"4"	"156"	"17.7"	"10.45"	"1820.18"	"6.49"	"4"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00276, Pf03939"	"6147"	"ENSG00000198242"	"RPL23A"	"B2R5B2; hsa:6147; P29316; P39024; P62750; Q92774"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"194.6"	"161.4"	"207.4"	"170.2"	"192.2"	"184.0"	"566.4"	"4.7"	"1727.0"	"1769.7"	"2886.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVM9"	"Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2"	"0.000"	""	"5"	"3"	"4"	"3"	"706"	"80.2"	"6.70"	"798.20"	"6.48"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf10221"	"55726"	"ENSG00000064102"	"INTS13"	"B4DNK1; hsa:55726; Q86WE2; Q96HM2; Q9BTX2; Q9NTB6; Q9NVM5; Q9NVM9"	"RNA polymerase II transcribes snRNA genes"	"1p36 copy number variation syndrome"	"2"	"0"	"55.6"	"36.9"	"64.9"	"48.5"	"41.0"	"54.2"	"86.0"	"0.0"	"821.1"	"892.3"	"1933.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L2E3"	"ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1"	"0.000"	""	"3"	"3"	"5"	"3"	"1194"	"133.9"	"8.78"	"847.02"	"6.48"	"3"	"2"	"cell organization and biogenesis;developmental processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"22907"	"ENSG00000132153"	"DHX30"	"A8K5F1; hsa:22907; O94965; Q7L2E3; Q7Z753; Q96CH4; Q9NUQ0"	""	""	"0"	"0"	"16.3"	"12.3"	"22.9"	"16.1"	"28.1"	"26.0"	"80.0"	"5.4"	"814.0"	"918.4"	"2355.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93096"	"Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2"	"0.000"	""	"15"	"2"	"4"	"2"	"173"	"19.8"	"8.97"	"712.91"	"6.46"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00782"	"7803"	"ENSG00000112245"	"PTP4A1"	"B2R6C8; hsa:7803; O00648; Q49A54; Q93096"	""	""	"0"	"0"	"30.7"	"26.0"	"35.2"	"45.6"	"27.8"	"38.8"	"89.0"	"1.2"	"531.0"	"525.7"	"927.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39880"	"Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1505"	"164.1"	"5.90"	"713.67"	"6.44"	"2"	"2"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf02376"	"1523"	"ENSG00000257923"	"CUX1"	"B3KV79; J3KQV9; P39880; Q6NYH4; Q75LE5; Q75MT2; Q75MT3; Q86UJ7; Q9UEV5"	"Signaling by FGFR1 in disease; Signaling by cytosolic FGFR1 fusion mutants"	""	"2"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.6"	"2.8"	"89.5"	"87.5"	"181.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92889"	"DNA repair endonuclease XPF OS=Homo sapiens OX=9606 GN=ERCC4 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"916"	"104.4"	"6.93"	"975.75"	"6.44"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02732"	"2072"	"ENSG00000175595"	"ERCC4"	"A5PKV6; A8K111; hsa:2072; O00140; Q8TD83; Q92889"	"Fanconi Anemia Pathway; Dual incision in TC-NER; HDR through Single Strand Annealing (SSA); Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"8"	"0"	"39.6"	"28.5"	"30.3"	"35.2"	"30.0"	"35.9"	"62.4"	"2.3"	"496.8"	"486.0"	"970.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86X10"	"Ral GTPase-activating protein subunit beta OS=Homo sapiens OX=9606 GN=RALGAPB PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1494"	"166.7"	"6.79"	"684.81"	"6.43"	"2"	"2"	"other biological processes"	""	"enzyme regulator activity;other molecular function"	"Pf20412"	"57148"	"ENSG00000170471"	"RALGAPB"	"A2A2E8; A2A2E9; hsa:57148; Q5TG31; Q86X10; Q8N3D1; Q8WWC0; Q9H3X8; Q9UJR1; Q9ULK1; Q9Y3G9"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	""	"1"	"0"	"32.7"	"25.3"	"29.8"	"27.0"	"28.9"	"39.1"	"115.9"	"2.0"	"1195.9"	"1256.5"	"1864.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3U1"	"Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1"	"0.000"	""	"1"	"1"	"4"	"1"	"944"	"103.0"	"6.07"	"703.75"	"6.41"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf11701, Pf13181, Pf13432"	"55898"	"ENSG00000140553"	"UNC45A"	"A8K6F7; hsa:55898; Q7L3Y6; Q9H3U1; Q9H3U8; Q9NSE8; Q9NSE9"	""	""	"0"	"0"	"3.8"	"5.2"	"4.9"	"4.8"	"3.5"	"4.9"	"12.3"	"2.6"	"163.0"	"143.6"	"311.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60842"	"Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"406"	"46.1"	"5.48"	"1199.71"	"6.41"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1973"	"ENSG00000161960"	"EIF4A1"	"B2R6L8; D3DTP9; hsa:1973; J3QLC4; P04765; P60842; Q5U018; Q61516"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism"	"Translation factors; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Interferon type I signaling pathways"	"11"	"0"	"40.7"	"30.0"	"46.9"	"38.0"	"42.3"	"44.3"	"57.0"	"11.9"	"210.3"	"198.1"	"375.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5T5"	"Ubiquitin carboxyl-terminal hydrolase 16 OS=Homo sapiens OX=9606 GN=USP16 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"823"	"93.5"	"6.93"	"615.39"	"6.41"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"translation activity;other molecular function"	"Pf00443, Pf02148"	"10600"	"ENSG00000156256"	"USP16"	"A8MU43; B3KN13; B4DFV8; B4DY37; D3DSD9; hsa:10600; Q53GP7; Q53HA0; Q5VKN8; Q8NEL3; Q9H3E6; Q9Y5T5"	"Ub-specific processing proteases"	""	"1"	"0"	"30.4"	"24.7"	"39.0"	"46.6"	"38.7"	"38.8"	"82.5"	"0.4"	"326.2"	"304.0"	"562.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HDC5"	"Junctophilin-1 OS=Homo sapiens OX=9606 GN=JPH1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"661"	"71.6"	"9.32"	"330.49"	"6.40"	"1"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus"	"other molecular function"	"Pf02493"	"56704"	"ENSG00000104369"	"JPH1"	"B2RTZ0; hsa:56704; Q9HDC5"	""	""	"0"	"0"	"22.2"	"23.0"	"16.6"	"14.2"	"11.4"	"19.8"	"68.4"	"0.9"	"614.4"	"638.9"	"963.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23786"	"Carnitine O-palmitoyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=CPT2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"658"	"73.7"	"8.18"	"733.77"	"6.40"	"2"	"2"	"other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00755"	"1376"	"ENSG00000157184"	"CPT2"	"B2R6S0; hsa:1376; P23786; Q5SW68; Q9BQ26"	"PPARA activates gene expression; Carnitine metabolism"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Thermogenesis; Mitochondrial fatty acid oxidation disorders"	"9"	"0"	"6.2"	"3.0"	"6.0"	"2.8"	"4.5"	"5.4"	"15.2"	"0.0"	"75.2"	"85.2"	"163.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBJ5"	"Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"622"	"71.6"	"7.31"	"691.97"	"6.40"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf01755, Pf13704"	"79709"	"ENSG00000130309"	"COLGALT1"	"hsa:79709; Q8NBJ5; Q8NC64"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	"31.0"	"24.0"	"50.7"	"31.7"	"35.6"	"30.2"	"64.1"	"0.0"	"450.9"	"453.6"	"836.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6K1"	"DNA (cytosine-5)-methyltransferase 3A OS=Homo sapiens OX=9606 GN=DNMT3A PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"912"	"101.8"	"6.57"	"611.95"	"6.39"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf00855, Pf17980"	"1788"	"ENSG00000119772"	"DNMT3A"	"E9PEB8; hsa:1788; Q86TE8; Q86XF5; Q8IZV0; Q8WXU9; Q9Y6K1"	"RMTs methylate histone arginines; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation; SUMOylation of DNA methylation proteins"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency; Opioid receptor pathways"	"10"	"0"	"14.7"	"8.9"	"9.9"	"14.8"	"12.6"	"10.5"	"23.9"	"0.0"	"77.6"	"75.3"	"144.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92820"	"Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2"	"0.000"	""	"14"	"4"	"5"	"4"	"318"	"35.9"	"7.11"	"1084.42"	"6.39"	"3"	"2"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07722"	"8836"	"ENSG00000137563"	"GGH"	"hsa:8836; Q92820"	"Neutrophil degranulation"	"Fluoropyrimidine activity"	"2"	"0"	"70.7"	"58.6"	"80.5"	"82.2"	"80.0"	"109.5"	"315.7"	"15.3"	"2367.7"	"2162.5"	"5181.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43813"	"Glutathione S-transferase LANCL1 OS=Homo sapiens OX=9606 GN=LANCL1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"399"	"45.3"	"7.75"	"783.31"	"6.38"	"2"	"2"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05147"	"10314"	"ENSG00000115365"	"LANCL1"	"hsa:10314; O43813"	""	""	"0"	"0"	"11.0"	"12.3"	"8.8"	"11.8"	"9.2"	"14.0"	"28.5"	"2.7"	"280.8"	"278.9"	"541.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N806"	"Putative E3 ubiquitin-protein ligase UBR7 OS=Homo sapiens OX=9606 GN=UBR7 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"425"	"48.0"	"4.81"	"542.09"	"6.38"	"1"	"1"	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf02207"	"55148"	"ENSG00000012963; ENSG00000278787"	"UBR7"	"hsa:55148; Q86U21; Q86UA9; Q8N806; Q96BY0; Q9NVV6"	""	""	"0"	"0"	"5.0"	"2.8"	"4.0"	"4.7"	"4.7"	"11.4"	"15.2"	"0.0"	"115.9"	"107.8"	"331.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75530"	"Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2"	""	""	"2"	"1"	"2"	"1"	"441"	"50.2"	"7.03"	""	"6.38"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400"	"8726"	"ENSG00000074266"	"EED"	"A8K7V5; hsa:8726; O00149; O75530; Q6NTH2; Q7LDA5; Q7LDG8; Q86VV2; Q9UNY7"	"Transcriptional Regulation by E2F6; HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis"	"Histone modifications; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma; 5q35 copy number variation"	"15"	"0"	"11.2"	"11.2"	"16.0"	"13.5"	"15.1"	"13.5"	"24.4"	"0.0"	"181.2"	"176.1"	"387.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A3KN83"	"Protein strawberry notch homolog 1 OS=Homo sapiens OX=9606 GN=SBNO1 PE=1 SV=1"	""	""	"2"	"2"	"2"	"2"	"1393"	"154.2"	"7.88"	""	"6.38"	""	"2"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13871, Pf13872"	"55206"	"ENSG00000139697"	"SBNO1"	"A3KN83; hsa:55206; Q05C06; Q3ZTS3; Q9H3T8; Q9NVB2"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"6.7"	"4.2"	"186.7"	"202.5"	"490.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35227"	"Polycomb group RING finger protein 2 OS=Homo sapiens OX=9606 GN=PCGF2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"3"	"2"	"344"	"37.8"	"7.96"	"240.63"	"6.37"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13923, Pf16207"	"7703"	"ENSG00000277258; ENSG00000278644"	"PCGF2"	"A6NGD8; hsa:7703; P35227"	"Transcriptional Regulation by E2F6; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; Activation of anterior HOX genes in hindbrain development during early embryogenesis"	"17q12 copy number variation syndrome"	"8"	"0"	"10.5"	"5.2"	"17.3"	"10.6"	"15.6"	"14.7"	"26.9"	"0.0"	"359.8"	"348.0"	"771.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW92"	"Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"718"	"81.0"	"7.30"	"400.96"	"6.37"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"80222"	"ENSG00000143374"	"TARS2"	"hsa:80222; Q53GW7; Q96I50; Q9BW92; Q9H9V2"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"6.4"	"4.8"	"5.0"	"9.2"	"7.0"	"11.2"	"14.4"	"3.6"	"237.6"	"244.0"	"542.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYW2"	"Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3"	"0.000"	""	"1"	"3"	"5"	"3"	"2564"	"287.4"	"6.14"	"713.53"	"6.37"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00856, Pf08236, Pf17907"	"29072"	"ENSG00000181555"	"SETD2"	"hsa:29072; O75397; O75405; Q17RW8; Q5BKS9; Q5QGN2; Q69YI5; Q6IN64; Q6ZN53; Q6ZS25; Q8N3R0; Q8TCN0; Q9BYW2; Q9C0D1; Q9H696; Q9NZW9"	"PKMTs methylate histone lysines"	"Histone modifications; Mesodermal commitment pathway; Mesodermal commitment pathway; Pathways affected in adenoid cystic carcinoma; Clear cell renal cell carcinoma pathways; Type 2 papillary renal cell carcinoma; Pleural mesothelioma"	"8"	"0"	"25.6"	"19.2"	"18.9"	"30.2"	"22.5"	"22.0"	"36.1"	"3.5"	"183.3"	"178.5"	"328.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43324"	"Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1"	"0.000"	""	"12"	"2"	"3"	"2"	"174"	"19.8"	"8.54"	"391.26"	"6.35"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00043"	"9521"	"ENSG00000124802"	"EEF1E1"	"C9JLK5; hsa:9521; O43324; Q5THS2"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	""	"2"	"0"	"18.0"	"20.5"	"24.5"	"19.8"	"24.0"	"22.5"	"30.7"	"0.0"	"420.5"	"488.1"	"1156.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35606"	"Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"906"	"102.4"	"5.27"	"567.44"	"6.34"	"2"	"2"	"transport"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00400, Pf04053"	"9276"	"ENSG00000184432"	"COPB2"	"B4DZI8; hsa:9276; P35606"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	""	"2"	"0"	"61.4"	"35.9"	"67.8"	"57.3"	"58.2"	"53.8"	"58.0"	"2.3"	"305.4"	"281.0"	"628.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16594"	"Transcription initiation factor TFIID subunit 9 OS=Homo sapiens OX=9606 GN=TAF9 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"264"	"29.0"	"8.66"	"459.03"	"6.34"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02291"	"6880"	"ENSG00000273841; ENSG00000276463"	"TAF9"	"D3DWA3; hsa:6880; Q16594; Q5U0D1; Q9BTS1"	"HATs acetylate histones; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"Eukaryotic transcription initiation"	"12"	"0"	"7.1"	"7.8"	"7.9"	"7.7"	"7.1"	"5.0"	"13.6"	"0.0"	"118.5"	"107.9"	"210.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54619"	"5'-AMP-activated protein kinase subunit gamma-1 OS=Homo sapiens OX=9606 GN=PRKAG1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"331"	"37.6"	"6.92"	"602.89"	"6.34"	"1"	"1"	"protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00571"	"5571"	"ENSG00000181929"	"PRKAG1"	"B4DDT7; hsa:5571; P54619; Q8N7V9"	"Regulation of TP53 Activity through Phosphorylation; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Activation of AMPK downstream of NMDARs; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Lipophagy"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Sterol regulatory element-binding proteins (SREBP) signaling; Angiopoietin-like protein 8 regulatory pathway; Leptin and adiponectin; Lipid metabolism pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; Pleural mesothelioma"	"23"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"83.7"	"99.0"	"267.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12532"	"Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1"	"0.000"	""	"2"	"1"	"4"	"1"	"417"	"47.0"	"8.34"	"708.48"	"6.33"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1159; 548596"	"ENSG00000223572; ENSG00000237289"	"CKMT1A; CKMT1B"	"B4DIT8; B7ZA09; hsa:1159; hsa:548596; P12532; Q0VAM3; Q32NF6; Q53FC4"	"Creatine metabolism"	""	"1"	"0"	"28.4"	"19.4"	"38.9"	"28.4"	"21.7"	"31.0"	"128.1"	"1.2"	"594.2"	"615.1"	"890.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVC6"	"Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"651"	"72.8"	"7.44"	"331.91"	"6.33"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10156"	"9440"	"ENSG00000042429"	"MED17"	"B3KN07; hsa:9440; Q9HA81; Q9NVC6; Q9UNP7; Q9Y2W0; Q9Y660"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	""	"3"	"0"	"7.2"	"3.7"	"7.0"	"3.0"	"4.1"	"10.0"	"20.3"	"2.4"	"125.4"	"107.9"	"277.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28331"	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"727"	"79.4"	"6.23"	"870.77"	"6.32"	"3"	"2"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00384, Pf09326, Pf10588, Pf13510"	"4719"	"ENSG00000023228; ENSG00000283447"	"NDUFS1"	"B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; hsa:4719; P28331; Q53TR8; Q8N1C4; Q8TCC9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"7.9"	"9.3"	"10.8"	"5.6"	"12.3"	"7.9"	"22.9"	"1.8"	"347.0"	"325.7"	"601.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYB4"	"Guanine nucleotide-binding protein subunit beta-like protein 1 OS=Homo sapiens OX=9606 GN=GNB1L PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"327"	"35.6"	"7.97"	"545.79"	"6.30"	"1"	"1"	""	""	""	"Pf00400"	"54584"	"ENSG00000185838"	"GNB1L"	"hsa:54584; Q9BYB4; Q9H2S2; Q9H4M4"	""	"22q11.2 copy number variation syndrome"	"1"	"0"	"0.0"	"0.0"	"2.7"	"5.3"	"5.1"	"2.9"	"7.5"	"0.0"	"212.7"	"211.2"	"444.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZ95"	"Histone-lysine N-methyltransferase NSD3 OS=Homo sapiens OX=9606 GN=NSD3 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1437"	"161.5"	"8.21"	"650.91"	"6.30"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00855, Pf00856, Pf17907, Pf17982"	"54904"	"ENSG00000147548"	"NSD3"	"B7ZL11; D3DSX1; hsa:54904; Q1RMD3; Q3B796; Q6ZSA5; Q9BYU8; Q9BYU9; Q9BZ95; Q9H2M8; Q9H9W9; Q9NXA6"	"PKMTs methylate histone lysines"	""	"1"	"0"	"5.6"	"4.7"	"6.9"	"4.3"	"8.6"	"5.5"	"12.5"	"0.0"	"201.9"	"196.5"	"477.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00584"	"Ribonuclease T2 OS=Homo sapiens OX=9606 GN=RNASET2 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"256"	"29.5"	"7.08"	"633.05"	"6.29"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"non-structural extracellular;mitochondrion;ER/Golgi;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00445"	"8635"	"ENSG00000026297"	"RNASET2"	"B2RDA7; E1P5C3; hsa:8635; O00584; Q5T8Q0; Q8TCU2; Q9BZ46; Q9BZ47"	"Neutrophil degranulation"	""	"1"	"0"	"0.0"	"2.4"	"0.0"	"1.7"	"1.8"	"2.7"	"4.3"	"0.0"	"225.9"	"279.1"	"759.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBP9"	"PTB domain-containing engulfment adapter protein 1 OS=Homo sapiens OX=9606 GN=GULP1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"304"	"34.5"	"7.90"	"593.90"	"6.28"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other cell component"	""	"Pf00640"	"51454"	"ENSG00000144366"	"GULP1"	"B2RB51; B4DQ40; B8ZZ72; D3DPH1; E9PB86; hsa:51454; Q53PC1; Q53RF3; Q9BVL3; Q9UBP9"	""	""	"0"	"0"	"18.6"	"15.1"	"9.3"	"11.9"	"16.9"	"21.9"	"34.3"	"0.5"	"268.5"	"259.0"	"380.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHV9"	"Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1"	"0.000"	""	"14"	"2"	"4"	"2"	"154"	"16.6"	"6.58"	"603.64"	"6.28"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5202"	"ENSG00000143256"	"PFDN2"	"hsa:5202; Q9P0P7; Q9UHV9; Q9UN05"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis"	"2"	"0"	"17.5"	"12.5"	"25.3"	"24.7"	"22.6"	"25.4"	"47.6"	"5.3"	"664.4"	"623.4"	"1432.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15404"	"Ras suppressor protein 1 OS=Homo sapiens OX=9606 GN=RSU1 PE=1 SV=3"	""	""	"9"	"1"	"1"	"1"	"277"	"31.5"	"8.65"	""	"6.28"	""	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	""	"Pf13855"	"6251"	"ENSG00000148484"	"RSU1"	"A8KA46; D3DRU3; hsa:6251; Q15404; Q6FI17"	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	""	"1"	"0"	"7.6"	"3.9"	"23.1"	"10.1"	"11.4"	"12.7"	"18.1"	"1.9"	"101.7"	"96.0"	"247.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15286"	"Ras-related protein Rab-35 OS=Homo sapiens OX=9606 GN=RAB35 PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"201"	"23.0"	"8.29"	"705.83"	"6.28"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"11021"	"ENSG00000111737"	"RAB35"	"B2R6E0; B4E390; hsa:11021; Q15286"	"RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation; TBC/RABGAPs"	""	"3"	"0"	"21.1"	"11.6"	"15.3"	"21.5"	"14.4"	"18.6"	"40.6"	"1.0"	"287.6"	"276.8"	"554.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84090"	"Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1"	"0.000"	""	"27"	"2"	"3"	"2"	"104"	"12.3"	"5.92"	"231.28"	"6.27"	"1"	"2"	"cell cycle OR cell proliferation;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01133"	"2079"	"ENSG00000100632"	"ERH"	"B2R5H2; hsa:2079; P70659; P84090; Q14259"	""	""	"0"	"0"	"21.4"	"28.9"	"27.7"	"24.6"	"26.1"	"29.3"	"84.3"	"0.0"	"442.0"	"527.3"	"673.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62273"	"40S ribosomal protein S29 OS=Homo sapiens OX=9606 GN=RPS29 PE=1 SV=2"	"0.000"	""	"27"	"3"	"4"	"3"	"56"	"6.7"	"10.13"	"230.69"	"6.27"	"1"	"3"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00253"	"6235"	"ENSG00000213741"	"RPS29"	"A8MZ73; hsa:6235; P30054; P62273"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"224.8"	"181.4"	"250.3"	"208.4"	"206.3"	"163.4"	"935.5"	"0.0"	"1910.2"	"1897.3"	"3617.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60911"	"Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"1"	"334"	"37.3"	"8.76"	"269.68"	"6.26"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1515"	"ENSG00000136943"	"CTSV"	"hsa:1515; O60233; O60911; Q2TB86; Q5T1U0"	"MHC class II antigen presentation; Assembly of collagen fibrils and other multimeric structures; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway; Activation of Matrix Metalloproteinases"	"Endochondral ossification; Endochondral ossification with skeletal dysplasias; Pancreatic cancer subtypes"	"10"	"1"	"39.7"	"42.6"	"42.7"	"41.2"	"43.6"	"61.7"	"137.6"	"0.0"	"1102.7"	"1194.5"	"2208.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43257"	"Zinc finger HIT domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZNHIT1 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"154"	"17.5"	"9.41"	"600.01"	"6.26"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04438"	"10467"	"ENSG00000106400"	"ZNHIT1"	"hsa:10467; O43257; Q6IB12"	""	""	"0"	"0"	"19.8"	"11.4"	"22.8"	"11.6"	"20.2"	"14.5"	"18.3"	"0.0"	"366.6"	"398.3"	"746.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61081"	"NEDD8-conjugating enzyme Ubc12 OS=Homo sapiens OX=9606 GN=UBE2M PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"183"	"20.9"	"7.69"	"618.20"	"6.26"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"9040"	"ENSG00000130725"	"UBE2M"	"hsa:9040; O76069; P61081; Q8VC50"	"Antigen processing: Ubiquitination & Proteasome degradation; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Neddylation; TGF-beta receptor signaling activates SMADs"	""	"5"	"0"	"31.1"	"16.7"	"34.4"	"26.5"	"32.8"	"26.6"	"40.4"	"1.3"	"408.9"	"414.3"	"1551.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60604"	"Ubiquitin-conjugating enzyme E2 G2 OS=Homo sapiens OX=9606 GN=UBE2G2 PE=1 SV=1"	""	""	"15"	"1"	"1"	"1"	"165"	"18.6"	"4.70"	""	"6.26"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf00179"	"7327"	"ENSG00000184787"	"UBE2G2"	"A6NMQ7; A8K3L4; D3DSL7; hsa:7327; P56554; P60604"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"4"	"0"	"5.3"	"4.6"	"11.2"	"5.2"	"8.9"	"7.5"	"13.6"	"0.0"	"99.5"	"93.2"	"158.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56385"	"ATP synthase subunit e, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5ME PE=1 SV=2"	"0.000"	""	"29"	"2"	"4"	"1"	"69"	"7.9"	"9.35"	"645.78"	"6.26"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05680"	"521"	"ENSG00000169020"	"ATP5ME"	"hsa:521; P56385; Q0D2L9"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"4"	"0"	"20.9"	"10.9"	"14.8"	"16.4"	"16.0"	"15.9"	"47.8"	"0.0"	"270.5"	"258.2"	"476.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q70Z53"	"Protein FRA10AC1 OS=Homo sapiens OX=9606 GN=FRA10AC1 PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"315"	"37.5"	"8.10"	"608.23"	"6.25"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf09725"	"118924"	"ENSG00000148690"	"FRA10AC1"	"C9JCR4; C9JCR5; C9JMY4; hsa:118924; Q70Z49; Q70Z50; Q70Z51; Q70Z52; Q70Z53; Q8N293; Q8WVH5; Q96JQ8"	""	""	"0"	"0"	"3.6"	"6.3"	"8.7"	"7.9"	"7.5"	"7.7"	"19.4"	"3.5"	"161.9"	"167.2"	"321.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P28070"	"Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4"	""	""	"9"	"1"	"2"	"1"	"264"	"29.2"	"5.97"	""	"6.23"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5692"	"ENSG00000159377"	"PSMB4"	"B2R9L3; hsa:5692; P28070; P31148; Q5SZS5; Q6IBI4; Q969L6"	"Regulation of expression of SLITs and ROBOs; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"7.4"	"6.3"	"7.7"	"7.3"	"8.3"	"6.0"	"18.9"	"1.7"	"70.9"	"80.4"	"125.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UBH6"	"Xenotropic and polytropic retrovirus receptor 1 OS=Homo sapiens OX=9606 GN=XPR1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"696"	"81.5"	"8.44"	""	"6.23"	""	"1"	"stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf03105, Pf03124"	"9213"	"ENSG00000143324"	"XPR1"	"hsa:9213; O95719; Q7L8K9; Q8IW20; Q9NT19; Q9UBH6; Q9UFB9"	""	""	"0"	"0"	"10.4"	"8.0"	"24.2"	"13.3"	"10.3"	"8.4"	"19.5"	"1.5"	"129.5"	"117.0"	"327.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94776"	"Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"668"	"75.0"	"9.66"	"470.26"	"6.23"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf01426, Pf01448, Pf17226"	"9219"	"ENSG00000149480"	"MTA2"	"hsa:9219; O94776; Q68DB1; Q9UQB5"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"7"	"0"	"83.4"	"53.4"	"80.1"	"65.5"	"73.8"	"68.3"	"95.7"	"3.2"	"513.5"	"520.4"	"1148.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z406"	"Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2"	"0.000"	""	"2"	"3"	"3"	"1"	"1995"	"227.7"	"5.60"	"414.94"	"6.22"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"79784"	"ENSG00000105357"	"MYH14"	"B0I1S2; C3TTN4; hsa:79784; Q5CZ75; Q6XYE4; Q76B62; Q7Z406; Q8WV23; Q96I22; Q9BT27; Q9BW35; Q9H882"	"RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases activate PAKs; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00154"	"Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"380"	"41.8"	"8.54"	"430.84"	"6.19"	"1"	"2"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf03061"	"11332"	"ENSG00000097021"	"ACOT7"	"A8K0K7; A8K232; A8K6B8; A8K837; B3KQ12; hsa:11332; O00154; O43703; Q53Y78; Q5JYL2; Q5JYL3; Q5JYL4; Q5JYL5; Q5JYL6; Q5TGR4; Q9UJM9; Q9Y539; Q9Y540"	"Mitochondrial Fatty Acid Beta-Oxidation"	""	"1"	"0"	"8.4"	"14.4"	"22.0"	"18.0"	"20.1"	"17.1"	"34.2"	"2.9"	"318.9"	"307.3"	"1069.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11388"	"DNA topoisomerase 2-alpha OS=Homo sapiens OX=9606 GN=TOP2A PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"1"	"1531"	"174.3"	"8.72"	"319.94"	"6.18"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00204, Pf00521, Pf01751, Pf02518, Pf08070, Pf16898"	"7153"	"ENSG00000131747"	"TOP2A"	"B2RTS1; hsa:7153; P11388; Q71UN1; Q71UQ5; Q9HB24; Q9HB25; Q9HB26; Q9UP44; Q9UQP9"	"SUMOylation of DNA replication proteins; Transcription of E2F targets under negative control by DREAM complex"	"Gastric cancer network 1; Gastric cancer network 2; Retinoblastoma gene in cancer"	"5"	"0"	"6.9"	"3.8"	"9.7"	"6.1"	"8.9"	"6.2"	"14.3"	"0.6"	"117.1"	"130.5"	"218.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94979"	"Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3"	"0.000"	""	"3"	"3"	"5"	"3"	"1220"	"132.9"	"6.89"	"1217.73"	"6.18"	"3"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf12931"	"22872"	"ENSG00000138674"	"SEC31A"	"B4DIW6; B7ZKZ7; B7ZL00; H7C2W3; hsa:22872; O94979; Q17RR5; Q5H9P6; Q5XG74; Q659G7; Q6ZU90; Q7LCX9; Q86TJ0; Q8IZH4; Q9P048; Q9P0A6; Q9UM05; Q9UM06"	"MHC class II antigen presentation; Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport; XBP1(S) activates chaperone genes; Antigen Presentation: Folding, assembly and peptide loading of class I MHC"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"6"	"0"	"39.6"	"40.3"	"55.2"	"49.4"	"43.2"	"44.2"	"98.7"	"3.2"	"847.5"	"843.7"	"1715.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NDT2"	"Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"1"	"890"	"97.1"	"9.85"	"715.55"	"6.18"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"29890"	"ENSG00000259956"	"RBM15B"	"A4QPG7; hsa:29890; Q6QE19; Q8NDT2; Q9BV96"	""	""	"0"	"0"	"17.9"	"10.8"	"18.2"	"19.7"	"27.8"	"21.6"	"46.0"	"6.2"	"443.3"	"387.4"	"777.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMN6"	"Histone-lysine N-methyltransferase 2B OS=Homo sapiens OX=9606 GN=KMT2B PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"2715"	"293.3"	"8.22"	"549.73"	"6.17"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"9757"	"ENSG00000272333"	"KMT2B"	"O15022; O95836; Q96GP2; Q96IP3; Q9UK25; Q9UMN6; Q9Y668; Q9Y669"	"PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"Histone modifications"	"4"	"0"	"27.5"	"18.6"	"37.3"	"26.6"	"30.0"	"34.4"	"48.2"	"4.5"	"324.0"	"324.8"	"602.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6H7"	"ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1"	"0.000"	""	"6"	"3"	"5"	"3"	"521"	"56.7"	"7.99"	"955.13"	"6.15"	"3"	"2"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"84364"	"ENSG00000149182"	"ARFGAP2"	"B4DX29; B7Z9M7; D3DQQ9; hsa:84364; Q3LIF2; Q8N3I1; Q8N6H7; Q96SX7"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; CDC42 GTPase cycle"	"IL-18 signaling pathway; 5q35 copy number variation"	"5"	"0"	"58.9"	"49.1"	"54.3"	"54.3"	"49.4"	"55.0"	"85.8"	"2.9"	"368.0"	"360.4"	"594.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13084"	"39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4"	"0.000"	""	"7"	"2"	"4"	"2"	"256"	"30.1"	"8.29"	"684.06"	"6.15"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00830"	"10573"	"ENSG00000086504"	"MRPL28"	"B2RCM4; D3DU46; hsa:10573; Q13084; Q4TT39; Q96S26; Q9BQD8; Q9BR04"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"132.7"	"84.2"	"144.6"	"106.7"	"100.9"	"146.8"	"297.9"	"0.0"	"883.5"	"891.2"	"1593.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93075"	"Putative deoxyribonuclease TATDN2 OS=Homo sapiens OX=9606 GN=TATDN2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"761"	"85.0"	"7.39"	"730.40"	"6.13"	"2"	"2"	""	"nucleus"	"other molecular function"	"Pf01026"	"9797"	"ENSG00000157014"	"TATDN2"	"hsa:9797; Q3MIL9; Q5BKU0; Q93075"	"XBP1(S) activates chaperone genes"	""	"1"	"0"	"45.7"	"32.3"	"41.1"	"43.0"	"35.9"	"39.9"	"119.8"	"3.6"	"500.8"	"495.1"	"899.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9F9"	"Actin-related protein 5 OS=Homo sapiens OX=9606 GN=ACTR5 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"607"	"68.3"	"5.27"	"515.62"	"6.12"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00022"	"79913"	"ENSG00000101442"	"ACTR5"	"hsa:79913; Q86WF7; Q8IUY5; Q8N724; Q9BRN0; Q9BVB7; Q9H9F9"	"UCH proteinases; DNA Damage Recognition in GG-NER"	""	"2"	"0"	"11.3"	"6.2"	"10.9"	"12.2"	"8.4"	"11.5"	"16.9"	"0.0"	"307.2"	"304.7"	"572.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86UK7"	"E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"904"	"98.6"	"8.40"	""	"6.12"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"enzyme regulator activity;translation activity;other molecular function"	""	"90850"	""	"ZNF598"	"hsa:90850; Q86UK7; Q8IW49; Q8N3D9; Q96FG3; Q9H7J3"	""	""	"0"	"0"	"13.4"	"15.5"	"13.3"	"15.9"	"14.4"	"20.3"	"23.2"	"1.6"	"88.1"	"102.9"	"223.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N668"	"COMM domain-containing protein 1 OS=Homo sapiens OX=9606 GN=COMMD1 PE=1 SV=1"	""	""	"11"	"1"	"1"	"1"	"190"	"21.2"	"6.20"	""	"6.11"	""	"1"	"DNA metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07258, Pf17221"	"150684"	"ENSG00000173163"	"COMMD1"	"B4DFQ4; hsa:150684; Q8N668; Q96GS0"	"Neddylation"	"Copper homeostasis; 1p36 copy number variation syndrome"	"3"	"0"	"0.0"	"0.0"	"6.0"	"2.5"	"4.0"	"6.0"	"5.4"	"1.0"	"90.7"	"89.2"	"246.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60002"	"Transcription elongation factor 1 homolog OS=Homo sapiens OX=9606 GN=ELOF1 PE=1 SV=1"	""	""	"22"	"1"	"1"	"1"	"83"	"9.5"	"8.00"	""	"6.10"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf05129"	"84337"	"ENSG00000130165"	"ELOF1"	"hsa:84337; P60002; Q8R1J7; Q96II4"	""	""	"0"	"0"	"31.2"	"20.0"	"34.3"	"35.7"	"35.8"	"27.1"	"40.0"	"0.2"	"604.2"	"555.1"	"883.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7D0"	"Dedicator of cytokinesis protein 5 OS=Homo sapiens OX=9606 GN=DOCK5 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1870"	"215.2"	"7.96"	"653.02"	"6.10"	"2"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf06920, Pf14429, Pf16172, Pf20421, Pf20422"	"80005"	"ENSG00000147459"	"DOCK5"	"B2RNY0; hsa:80005; Q5XKD5; Q6AI11; Q6PJS6; Q6ZTS6; Q9H7D0"	"RHOG GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	"Ciliary landscape"	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"41.3"	"35.1"	"89.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P266"	"Junctional protein associated with coronary artery disease OS=Homo sapiens OX=9606 GN=JCAD PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"1359"	"148.3"	"7.09"	"403.18"	"6.10"	"1"	"2"	"cell adhesion;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf15351"	"57608"	"ENSG00000165757"	"JCAD"	"hsa:57608; Q5HYA7; Q5T992; Q86WZ9; Q9BYJ2; Q9P266"	""	""	"0"	"0"	"30.4"	"22.8"	"27.3"	"33.2"	"28.8"	"28.7"	"65.8"	"0.0"	"315.9"	"325.3"	"570.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXX6"	"Non-structural maintenance of chromosomes element 4 homolog A OS=Homo sapiens OX=9606 GN=NSMCE4A PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"385"	"44.3"	"5.38"	"785.24"	"6.10"	"2"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf08743, Pf15412"	"54780"	"ENSG00000107672"	"NSMCE4A"	"hsa:54780; Q5SQQ5; Q6P673; Q8WY66; Q9BS90; Q9NXX6"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"17.5"	"12.7"	"23.1"	"22.3"	"21.1"	"19.1"	"62.6"	"0.8"	"355.7"	"341.1"	"766.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04844"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"631"	"69.2"	"5.69"	"560.78"	"6.07"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cytoplasmic organelle"	"translation activity"	"Pf05817"	"6185"	"ENSG00000118705"	"RPN2"	"hsa:6185; P04844; Q5JYR6; Q6IBA5; Q96E21; Q9BUQ3; Q9UBE1"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"Proteasome degradation; N-glycan biosynthesis"	"5"	"0"	"0.0"	"0.0"	"3.9"	"0.0"	"3.4"	"2.6"	"3.5"	"0.0"	"161.4"	"153.0"	"526.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94804"	"Serine/threonine-protein kinase 10 OS=Homo sapiens OX=9606 GN=STK10 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"968"	"112.1"	"6.95"	"228.61"	"6.07"	"1"	"2"	"cell adhesion;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12474"	"6793"	"ENSG00000072786"	"STK10"	"A6ND35; B2R8F5; B3KMY1; hsa:6793; O94804; Q6NSK0; Q9UIW4"	"RHOA GTPase cycle; RHOB GTPase cycle; RHOC GTPase cycle; Neutrophil degranulation"	""	"4"	"0"	"25.8"	"26.2"	"32.3"	"32.6"	"27.8"	"29.1"	"78.8"	"0.0"	"738.4"	"769.5"	"1720.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q56P03"	"E2F-associated phosphoprotein OS=Homo sapiens OX=9606 GN=EAPP PE=1 SV=4"	"0.000"	""	"5"	"2"	"4"	"2"	"285"	"32.7"	"5.12"	"612.56"	"6.05"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf10238"	"55837"	"ENSG00000129518"	"EAPP"	"hsa:55837; Q56P03; Q9BVF4; Q9NWV5; Q9NZ86"	""	""	"0"	"0"	"5.2"	"6.8"	"8.1"	"9.6"	"9.3"	"4.5"	"13.7"	"1.3"	"43.4"	"49.8"	"88.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20936"	"Ras GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RASA1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1047"	"116.3"	"6.54"	"563.52"	"6.05"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00169, Pf00616"	"5921"	"ENSG00000145715"	"RASA1"	"B2R6W3; B4DTL2; hsa:5921; P20936; Q68CU6; Q9UDI1"	"Regulation of RAS by GAPs; EPHB-mediated forward signaling; Downstream signal transduction; VEGFR2 mediated cell proliferation; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"Androgen receptor network in prostate cancer; PDGF pathway; T cell receptor and co-stimulatory signaling; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; Ras signaling; Acute viral myocarditis; EGF/EGFR signaling pathway; GDNF signaling; EPO receptor signaling"	"16"	"0"	"2.1"	"0.0"	"4.4"	"6.5"	"3.0"	"0.0"	"16.8"	"7.2"	"449.3"	"423.7"	"971.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKG9"	"Peroxisomal carnitine O-octanoyltransferase OS=Homo sapiens OX=9606 GN=CROT PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"612"	"70.1"	"7.08"	"436.31"	"6.03"	"1"	"2"	"other metabolic processes;transport"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00755"	"54677"	"ENSG00000005469"	"CROT"	"A4D1D6; E7EQF2; hsa:54677; Q86V17; Q8IUW9; Q9UKG9; Q9Y6I2"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	""	"2"	"0"	"0.0"	"0.0"	"5.2"	"5.3"	"3.5"	"2.1"	"8.5"	"0.0"	"57.0"	"54.8"	"87.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UNF1"	"Melanoma-associated antigen D2 OS=Homo sapiens OX=9606 GN=MAGED2 PE=1 SV=2"	""	""	"4"	"1"	"2"	"1"	"606"	"64.9"	"9.32"	""	"6.03"	""	"1"	"transport;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01454"	"10916"	"ENSG00000102316"	"MAGED2"	"A6NMX0; hsa:10916; O76058; Q5BJF3; Q8NAL6; Q9H218; Q9P0U9; Q9UM52; Q9UNF1"	"Platelet degranulation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8MWD9"	"Putative small nuclear ribonucleoprotein G-like protein 15 OS=Homo sapiens OX=9606 GN=SNRPGP15 PE=5 SV=2"	"0.000"	""	"25"	"2"	"4"	"2"	"76"	"8.5"	"8.84"	"650.44"	"6.03"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	""	""	"SNRPGP15"	"A8MWD9"	""	""	"0"	"0"	"71.0"	"56.2"	"70.0"	"67.5"	"66.7"	"64.5"	"139.8"	"2.0"	"641.5"	"694.1"	"1430.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86T24"	"Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"672"	"74.4"	"5.12"	"499.16"	"6.03"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00651"	"10009"	"ENSG00000177485"	"ZBTB33"	"B2R5U6; hsa:10009; O00319; Q7Z361; Q86T24; Q8IVP6; Q8N3P0"	""	"Wnt signaling pathway and pluripotency"	"1"	"0"	"27.9"	"22.4"	"27.5"	"22.6"	"27.1"	"15.4"	"40.1"	"0.0"	"142.6"	"136.6"	"241.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00442"	"RNA 3'-terminal phosphate cyclase OS=Homo sapiens OX=9606 GN=RTCA PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"366"	"39.3"	"7.85"	"537.78"	"6.02"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01137, Pf05189"	"8634"	"ENSG00000137996"	"RTCA"	"hsa:8634; O00442; Q5VVL5; Q5VVL6; Q96E99"	""	""	"0"	"0"	"11.1"	"6.4"	"18.9"	"12.0"	"13.5"	"15.0"	"30.9"	"2.6"	"242.1"	"224.4"	"507.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14649"	"Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"208"	"22.8"	"5.73"	"526.36"	"6.00"	"1"	"1"	"other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	""	"140465"	"ENSG00000196465"	"MYL6B"	"hsa:140465; P14649"	"Smooth Muscle Contraction"	"Ciliary landscape"	"2"	"0"	"5.8"	"10.4"	"7.3"	"9.6"	"6.1"	"7.6"	"17.7"	"0.0"	"171.6"	"184.2"	"412.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P26440"	"Isovaleryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=IVD PE=1 SV=2"	""	""	"4"	"2"	"2"	"2"	"426"	"46.6"	"8.05"	""	"5.99"	""	"2"	"other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"3712"	"ENSG00000128928"	"IVD"	"B2RCV5; B3KVI7; hsa:3712; J3KR54; P26440; Q53XZ9; Q96AF6"	"Branched-chain amino acid catabolism"	"Valproic acid pathway"	"2"	"0"	"22.4"	"9.2"	"26.6"	"22.5"	"29.9"	"31.0"	"41.6"	"0.0"	"295.2"	"291.9"	"638.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND56"	"Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"463"	"50.5"	"9.52"	"606.51"	"5.98"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"26065"	"ENSG00000257103; ENSG00000262860"	"LSM14A"	"B4DTG6; hsa:26065; Q76LX7; Q8ND56; Q96AR3; Q96K73; Q96SN5; Q9UFR3"	""	""	"0"	"0"	"66.0"	"47.7"	"64.5"	"75.6"	"71.4"	"75.5"	"154.9"	"0.2"	"361.0"	"338.7"	"644.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A5PLN9"	"Trafficking protein particle complex subunit 13 OS=Homo sapiens OX=9606 GN=TRAPPC13 PE=1 SV=2"	"0.000"	""	"6"	"2"	"2"	"2"	"417"	"46.5"	"5.60"	"272.18"	"5.98"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf06159"	"80006"	"ENSG00000113597"	"TRAPPC13"	"A5PLN9; hsa:80006; Q17RZ9; Q49A23; Q4JHG0; Q6MZG4; Q8TCM2; Q9H8I3"	"RAB GEFs exchange GTP for GDP on RABs"	""	"1"	"0"	"7.8"	"5.4"	"7.9"	"10.6"	"8.2"	"3.7"	"15.3"	"0.0"	"232.9"	"195.2"	"470.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWU0"	"Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"796"	"88.8"	"5.19"	"254.98"	"5.95"	"1"	"2"	""	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00498"	"22950"	"ENSG00000163798"	"SLC4A1AP"	"A6NJ39; hsa:22950; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9BWU0; Q9NVN2"	""	""	"0"	"0"	"36.1"	"25.5"	"39.7"	"33.0"	"35.0"	"39.8"	"88.5"	"0.0"	"571.8"	"609.2"	"1248.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15005"	"Signal peptidase complex subunit 2 OS=Homo sapiens OX=9606 GN=SPCS2 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"226"	"25.0"	"8.47"	"624.08"	"5.95"	"1"	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi"	""	"Pf06703"	"9789"	"ENSG00000118363"	"SPCS2"	"hsa:9789; Q15005; Q15507; Q3KQT0; Q641R4; Q6FG65; Q6IRX0; Q6P1P4; Q96HU9"	"SRP-dependent cotranslational protein targeting to membrane; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP); Synthesis, secretion, and deacylation of Ghrelin"	"15q25 copy number variation"	"5"	"0"	"3.3"	"5.6"	"3.2"	"5.7"	"4.1"	"0.0"	"9.5"	"0.0"	"93.8"	"93.7"	"148.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QZ7"	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MAGI1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1491"	"164.5"	"7.58"	"532.49"	"5.94"	"1"	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00595, Pf00625, Pf16663, Pf16666"	"9223"	"ENSG00000151276; ENSG00000282956"	"MAGI1"	"A8K188; hsa:9223; O00309; O43863; O75085; Q96QZ7; Q96QZ8; Q96QZ9"	""	"Pathways affected in adenoid cystic carcinoma"	"1"	"0"	"12.0"	"9.5"	"9.1"	"10.1"	"11.0"	"9.3"	"20.4"	"0.0"	"328.7"	"336.2"	"593.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N163"	"Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"923"	"102.8"	"5.22"	"688.78"	"5.94"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14443, Pf14444, Pf19256, Pf19257"	"57805"	"ENSG00000158941"	"CCAR2"	"A6NL03; B2RB79; D3DSR6; hsa:57805; Q6P0Q9; Q8N163; Q8N3G7; Q8N8M1; Q8TF34; Q9H9Q9; Q9HD12; Q9NT55"	"Regulation of HSF1-mediated heat shock response"	"TAR syndrome"	"2"	"0"	"140.5"	"113.5"	"115.2"	"133.9"	"109.2"	"118.8"	"147.9"	"0.0"	"397.3"	"402.8"	"709.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4W6"	"AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"797"	"88.5"	"8.66"	"220.85"	"5.94"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf01434, Pf06480, Pf17862"	"10939"	"ENSG00000141385"	"AFG3L2"	"hsa:10939; Q6P1L0; Q9Y4W6"	"Processing of SMDT1"	"Ciliary landscape; 10q22q23 copy number variation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99417"	"c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3"	"0.000"	""	"19"	"1"	"2"	"1"	"103"	"12.0"	"5.91"	"554.87"	"5.93"	"1"	"1"	"other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	""	"26292"	"ENSG00000214114"	"MYCBP"	"B2R4N0; hsa:26292; Q5TA64; Q96HE2; Q99417"	""	"Pathways affected in adenoid cystic carcinoma"	"1"	"0"	"4.8"	"0.0"	"2.4"	"4.2"	"2.7"	"2.7"	"10.5"	"0.3"	"282.3"	"278.5"	"725.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P41240"	"Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1"	""	""	"6"	"2"	"2"	"2"	"450"	"50.7"	"7.06"	""	"5.92"	""	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"1445"	"ENSG00000103653"	"CSK"	"hsa:1445; P41240; Q2M3N2; Q6FGZ6"	"Signaling by BRAF and RAF1 fusions; GAB1 signalosome; Integrin signaling; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Phosphorylation of CD3 and TCR zeta chains; PD-1 signaling; Negative regulation of FLT3; RHOH GTPase cycle"	"Integrin-mediated cell adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton"	"18"	"0"	"0.0"	"0.0"	"2.4"	"0.0"	"4.0"	"0.0"	"0.0"	"0.0"	"21.5"	"24.3"	"67.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15439"	"Multidrug resistance-associated protein 4 OS=Homo sapiens OX=9606 GN=ABCC4 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1325"	"149.4"	"8.19"	"632.59"	"5.92"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"10257"	"ENSG00000125257"	"ABCC4"	"A9Z1Z7; B7Z3Q7; hsa:10257; O15439; Q8IVZ4; Q8IZN6; Q8NEW8; Q9Y6J2"	"ABC-family proteins mediated transport; Paracetamol ADME; Platelet degranulation ; Azathioprine ADME"	"Fluoropyrimidine activity; Androgen receptor network in prostate cancer; Drug induction of bile acid pathway; Ectoderm differentiation; Pregnane X receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; TYROBP causal network in microglia; Aspirin and miRNAs; Proximal tubule transport; FOXA2 pathway; Prostaglandin synthesis and regulation"	"17"	"0"	"4.5"	"5.1"	"4.6"	"3.7"	"6.6"	"4.3"	"9.3"	"1.9"	"300.3"	"273.6"	"556.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY37"	"Probable ATP-dependent RNA helicase DHX37 OS=Homo sapiens OX=9606 GN=DHX37 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1157"	"129.5"	"8.10"	"726.01"	"5.92"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"57647"	"ENSG00000150990"	"DHX37"	"hsa:57647; Q8IY37; Q9BUI7; Q9P211"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"20.9"	"24.7"	"22.3"	"23.4"	"25.8"	"25.2"	"42.4"	"0.0"	"408.3"	"394.3"	"665.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y4Y9"	"U6 snRNA-associated Sm-like protein LSm5 OS=Homo sapiens OX=9606 GN=LSM5 PE=1 SV=3"	""	""	"25"	"1"	"1"	"1"	"91"	"9.9"	"4.54"	""	"5.91"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"23658"	"ENSG00000106355"	"LSM5"	"hsa:23658; Q9Y4Y9"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	""	"2"	"0"	"5.8"	"5.1"	"5.3"	"6.4"	"2.2"	"6.9"	"10.2"	"0.0"	"42.7"	"34.4"	"101.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Q4"	"Non-homologous end-joining factor 1 OS=Homo sapiens OX=9606 GN=NHEJ1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"299"	"33.3"	"5.97"	"447.38"	"5.90"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09302"	"79840"	"ENSG00000187736"	"NHEJ1"	"B8ZZA4; hsa:79840; Q4ZFW7; Q6IA64; Q96JS9; Q9H9Q4"	"Nonhomologous End-Joining (NHEJ)"	"Non-homologous end joining; DNA repair pathways, full network"	"3"	"0"	"6.7"	"5.0"	"10.3"	"8.1"	"8.7"	"6.0"	"14.2"	"1.2"	"144.7"	"150.6"	"355.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY1"	"DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"480"	"52.5"	"9.26"	"359.45"	"5.88"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00226, Pf00684, Pf01556"	"9093"	"ENSG00000103423; ENSG00000276726"	"DNAJA3"	"B2RAJ5; B4DI33; E7ES32; hsa:9093; O75472; Q8WUJ6; Q8WXJ3; Q96D76; Q96EY1; Q96IV1; Q9NYH8"	""	""	"0"	"0"	"7.5"	"5.8"	"13.7"	"9.8"	"12.5"	"10.2"	"23.9"	"1.5"	"226.2"	"243.8"	"434.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04114"	"Apolipoprotein B-100 OS=Homo sapiens OX=9606 GN=APOB PE=1 SV=2"	"0.000"	""	"0"	"1"	"4"	"1"	"4563"	"515.3"	"7.05"	"615.07"	"5.87"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf01347, Pf06448, Pf09172, Pf12491"	"338"	"ENSG00000084674"	"APOB"	"hsa:338; O00502; P04114; P78479; P78480; P78481; Q13779; Q13785; Q13786; Q13787; Q13788; Q4ZG63; Q53QC8; Q7Z600; Q9UMN0"	"Cell surface interactions at the vascular wall; Scavenging by Class B Receptors; Regulation of TLR by endogenous ligand; Heme signaling; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Retinoid metabolism and transport; Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Chylomicron clearance; Scavenging by Class A Receptors; Chylomicron assembly; Chylomicron remodeling; VLDL assembly; VLDL clearance; Scavenging by Class F Receptors; Scavenging by Class H Receptors; Platelet sensitization by LDL; LDL remodeling"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Statin inhibition of cholesterol production; Male infertility; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Familial hyperlipidemia type 2; Cholesterol metabolism; Female steroid hormones in cardiomyocyte energy metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes; Enterocyte cholesterol metabolism"	"31"	"0"	"0.0"	"4.3"	"5.4"	"3.9"	"5.7"	"5.4"	"12.8"	"4.6"	"158.9"	"162.6"	"395.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62879"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"340"	"37.3"	"6.00"	"384.90"	"5.87"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2783"	"ENSG00000172354"	"GNB2"	"B3KPU1; hsa:2783; P11016; P54312; P62879"	"G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"36"	"0"	"2.9"	"0.0"	"4.1"	"3.6"	"3.5"	"3.1"	"4.2"	"0.0"	"247.8"	"291.5"	"699.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q969S3"	"Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1"	""	""	"5"	"2"	"2"	"2"	"477"	"54.2"	"6.15"	""	"5.86"	""	"2"	"signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf12171, Pf12756"	"90441"	"ENSG00000173545"	"ZNF622"	"hsa:90441; Q969S3"	""	""	"0"	"0"	"11.7"	"18.0"	"16.1"	"17.8"	"16.8"	"16.8"	"32.6"	"1.5"	"199.4"	"203.2"	"530.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W34"	"Archaemetzincin-2 OS=Homo sapiens OX=9606 GN=AMZ2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"360"	"41.2"	"8.15"	"586.51"	"5.86"	"1"	"1"	"protein metabolism"	""	"other molecular function"	"Pf07998"	"51321"	"ENSG00000196704"	"AMZ2"	"A6NLD9; B3KR44; hsa:51321; Q5XKF1; Q86W34; Q9NZE2"	""	""	"0"	"0"	"3.2"	"3.2"	"7.1"	"6.9"	"6.8"	"4.4"	"10.5"	"0.0"	"109.2"	"154.5"	"278.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7KZI7"	"Serine/threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2"	""	""	"3"	"2"	"2"	"1"	"788"	"87.9"	"9.72"	""	"5.86"	""	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00627, Pf02149"	"2011"	"ENSG00000072518"	"MARK2"	"hsa:2011; Q15449; Q15524; Q5XGA3; Q68A18; Q7KZI7; Q96HB3; Q96RG0"	""	"Microtubule cytoskeleton regulation; Complement system in neuronal development and plasticity; Neurogenesis regulation in the olfactory epithelium"	"3"	"0"	"21.6"	"9.4"	"19.8"	"25.6"	"15.7"	"15.3"	"24.0"	"0.0"	"186.8"	"221.5"	"334.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P48200"	"Iron-responsive element-binding protein 2 OS=Homo sapiens OX=9606 GN=IREB2 PE=1 SV=4"	""	""	"5"	"2"	"2"	"2"	"963"	"105.0"	"7.05"	""	"5.85"	""	"2"	"other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00330, Pf00694"	"3658"	"ENSG00000136381"	"IREB2"	"A0A0A6YY96; A8KAC7; E1CJT9; H0YKU0; hsa:3658; P48200; Q13095; Q1HE21; Q59FQ7; Q8WVK6; Q9UF17"	"Iron uptake and transport"	"Iron metabolism in placenta; Ferroptosis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H0H5"	"Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"632"	"71.0"	"8.88"	""	"5.85"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00130, Pf00620"	"29127"	"ENSG00000161800"	"RACGAP1"	"hsa:29127; Q6PJ26; Q9H0H5; Q9NWN2; Q9P250; Q9P2W2"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle"	"S1P receptor signal transduction; Wnt signaling pathway and pluripotency"	"13"	"0"	"2.6"	"0.0"	"0.0"	"2.4"	"0.0"	"3.4"	"0.6"	"1.6"	"71.0"	"67.2"	"184.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15813"	"Tubulin-specific chaperone E OS=Homo sapiens OX=9606 GN=TBCE PE=1 SV=1"	""	""	"4"	"2"	"2"	"2"	"527"	"59.3"	"6.76"	""	"5.84"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf14560"	"6905"	"ENSG00000282984; ENSG00000284770; ENSG00000285053"	"TBCE"	"A8K8C2; B7Z3P1; hsa:6905; Q15813"	"Post-chaperonin tubulin folding pathway"	""	"1"	"0"	"16.0"	"5.4"	"14.4"	"13.9"	"11.7"	"11.5"	"14.3"	"0.0"	"169.7"	"168.9"	"485.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4H7"	"HAUS augmin-like complex subunit 6 OS=Homo sapiens OX=9606 GN=HAUS6 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"955"	"108.6"	"6.47"	"731.70"	"5.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf14661"	"54801"	"ENSG00000147874"	"HAUS6"	"B3KPK4; B4DX82; hsa:54801; Q05CG1; Q14CB6; Q14CD9; Q2TA91; Q6IQ10; Q6NZX5; Q7Z4H7; Q8IZQ4; Q96FN0; Q9H950; Q9H998; Q9HCJ8; Q9NXT8"	"Recruitment of mitotic centrosome proteins and complexes; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"18.5"	"14.6"	"17.9"	"28.7"	"17.3"	"20.3"	"34.0"	"2.2"	"173.4"	"163.6"	"313.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18615"	"Negative elongation factor E OS=Homo sapiens OX=9606 GN=NELFE PE=1 SV=3"	"0.000"	""	"10"	"3"	"5"	"3"	"380"	"43.2"	"9.33"	"1299.74"	"5.84"	"3"	"2"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7936"	"ENSG00000204356; ENSG00000206268; ENSG00000206357; ENSG00000229363; ENSG00000231044; ENSG00000233801"	"NELFE"	"A2BE08; B4DUN1; B4DYX9; hsa:7936; P18615; Q5JP74; Q5JP75; Q96F56; Q9NPK2"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"16"	"0"	"62.5"	"47.1"	"49.8"	"57.6"	"59.9"	"56.5"	"116.0"	"1.6"	"795.4"	"848.0"	"1552.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6P161"	"39S ribosomal protein L54, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL54 PE=1 SV=1"	""	""	"19"	"1"	"1"	"1"	"138"	"15.8"	"9.60"	""	"5.83"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf08561"	"116541"	"ENSG00000183617"	"MRPL54"	"hsa:116541; Q6P161"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"19.7"	"16.3"	"21.9"	"15.6"	"17.4"	"16.3"	"39.4"	"0.7"	"138.4"	"126.8"	"242.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UDY4"	"DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"337"	"37.8"	"8.50"	"240.99"	"5.83"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00226, Pf01556"	"11080"	"ENSG00000162616"	"DNAJB4"	"B2R824; hsa:11080; Q13431; Q9UDY4"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"11.3"	"7.8"	"9.7"	"7.7"	"11.6"	"8.6"	"20.4"	"0.8"	"79.5"	"77.6"	"166.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08378"	"Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"1498"	"167.3"	"5.44"	"330.23"	"5.82"	"1"	"2"	""	"other membranes;cytosol;ER/Golgi;nucleus"	""	""	"2802"	"ENSG00000090615"	"GOLGA3"	"A5PKX6; hsa:2802; O43241; Q08378; Q6P9C7; Q86XW3; Q8TDA9; Q8WZA3"	"RND2 GTPase cycle"	""	"1"	"0"	"9.0"	"2.4"	"8.0"	"13.2"	"6.4"	"6.3"	"17.5"	"0.6"	"151.1"	"133.6"	"297.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BU76"	"Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"263"	"29.4"	"10.02"	"683.64"	"5.82"	"2"	"2"	""	"non-structural extracellular;other cell component"	""	"Pf10159"	"79169"	"ENSG00000143793"	"MMTAG2"	"hsa:79169; Q6P5Y0; Q6ZTZ6; Q6ZWA6; Q8IZH3; Q9BU76"	"Neutrophil degranulation"	""	"1"	"0"	"85.1"	"65.2"	"82.8"	"70.4"	"77.4"	"54.0"	"226.2"	"8.6"	"976.1"	"979.5"	"1828.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42766"	"60S ribosomal protein L35 OS=Homo sapiens OX=9606 GN=RPL35 PE=1 SV=2"	"0.000"	""	"24"	"3"	"3"	"2"	"123"	"14.5"	"11.05"	"264.53"	"5.81"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00831"	"11224"	"ENSG00000136942"	"RPL35"	"A8K4V7; hsa:11224; P42766; Q4VBY5; Q5JTN5; Q6IBC7; Q96QJ7; Q9BYF4"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"26.7"	"15.6"	"29.4"	"15.1"	"19.2"	"20.6"	"59.3"	"0.0"	"215.6"	"201.0"	"438.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2W1"	"Homologous-pairing protein 2 homolog OS=Homo sapiens OX=9606 GN=PSMC3IP PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"217"	"24.9"	"7.81"	"614.50"	"5.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07106, Pf18517"	"29893"	"ENSG00000131470"	"PSMC3IP"	"C5ILB7; hsa:29893; Q14458; Q8WXG2; Q96HA2; Q9P2W1"	"Meiotic recombination"	"Androgen receptor signaling pathway; Primary ovarian insufficiency"	"3"	"0"	"6.0"	"6.4"	"9.3"	"5.6"	"4.8"	"4.6"	"18.9"	"3.3"	"128.0"	"122.0"	"200.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVC3"	"Sister chromatid cohesion protein DCC1 OS=Homo sapiens OX=9606 GN=DSCC1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"393"	"44.8"	"5.17"	"606.34"	"5.80"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09724"	"79075"	"ENSG00000136982"	"DSCC1"	"hsa:79075; Q969N5; Q9BVC3"	"Polymerase switching on the C-strand of the telomere"	"Gastric cancer network 2"	"2"	"0"	"8.7"	"3.0"	"9.9"	"4.9"	"10.9"	"9.1"	"15.7"	"2.5"	"193.6"	"219.4"	"468.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86X55"	"Histone-arginine methyltransferase CARM1 OS=Homo sapiens OX=9606 GN=CARM1 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"608"	"65.8"	"6.73"	""	"5.78"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06325, Pf11531"	"10498"	"ENSG00000142453"	"CARM1"	"A6NN38; hsa:10498; Q86X55"	"Estrogen-dependent gene expression; Cytoprotection by HMOX1; PPARA activates gene expression; RMTs methylate histone arginines; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Activation of gene expression by SREBF (SREBP); TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; RORA activates gene expression"	"Androgen receptor signaling pathway; Nitric oxide metabolism in cystic fibrosis"	"15"	"0"	"8.8"	"5.0"	"7.9"	"13.0"	"7.6"	"6.7"	"17.2"	"4.3"	"88.2"	"91.0"	"186.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3SXY8"	"ADP-ribosylation factor-like protein 13B OS=Homo sapiens OX=9606 GN=ARL13B PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"428"	"48.6"	"6.62"	"611.37"	"5.78"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00025"	"200894"	"ENSG00000169379"	"ARL13B"	"D3DN29; G3V1S8; hsa:200894; Q3SXY8; Q504W8; Q8TCL5"	"Aggrephagy; RHOQ GTPase cycle; RHOJ GTPase cycle; Late endosomal microautophagy; ARL13B-mediated ciliary trafficking of INPP5E; Chaperone Mediated Autophagy"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"10"	"0"	"0.0"	"3.1"	"3.8"	"4.6"	"6.3"	"4.4"	"10.4"	"0.0"	"74.7"	"77.9"	"161.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5J5"	"Pleckstrin homology-like domain family A member 3 OS=Homo sapiens OX=9606 GN=PHLDA3 PE=1 SV=1"	"0.000"	""	"14"	"2"	"4"	"2"	"127"	"13.9"	"9.67"	"669.63"	"5.77"	"2"	"2"	"stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	""	"23612"	"ENSG00000174307"	"PHLDA3"	"B2R5A4; hsa:23612; Q53HD6; Q8NBW9; Q9Y5J5"	""	""	"0"	"0"	"40.2"	"32.7"	"43.4"	"41.3"	"50.3"	"47.7"	"130.9"	"0.1"	"942.2"	"988.3"	"1612.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4LE39"	"AT-rich interactive domain-containing protein 4B OS=Homo sapiens OX=9606 GN=ARID4B PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1312"	"147.7"	"5.12"	"276.68"	"5.76"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf01388, Pf08169, Pf11717"	"51742"	"ENSG00000054267"	"ARID4B"	"A1L465; hsa:51742; Q3MHV4; Q4LE39; Q5HY99; Q5T2C2; Q5T2C3; Q5T2C4; Q5T2C5; Q5T2C6; Q6P600; Q86UX1; Q86WR4; Q9H915; Q9NYU3; Q9NZB6; Q9NZG4; Q9P2W4; Q9UF62; Q9Y6E1"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"Pathways affected in adenoid cystic carcinoma"	"4"	"0"	"24.9"	"21.5"	"28.5"	"22.6"	"21.1"	"18.8"	"33.8"	"1.4"	"131.6"	"120.6"	"257.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60524"	"Nuclear export mediator factor NEMF OS=Homo sapiens OX=9606 GN=NEMF PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"1076"	"122.9"	"6.35"	"543.37"	"5.76"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf05670, Pf05833, Pf11923"	"9147"	"ENSG00000165525"	"NEMF"	"A0JLQ3; B3KSK1; B4DDL3; B4DHA9; B4E3F3; hsa:9147; O60524; Q32Q66; Q8WW70; Q9NWG1"	""	""	"0"	"0"	"9.8"	"6.4"	"11.7"	"8.7"	"7.4"	"9.6"	"15.2"	"3.6"	"140.5"	"137.4"	"425.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TF01"	"Arginine/serine-rich protein PNISR OS=Homo sapiens OX=9606 GN=PNISR PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"805"	"92.5"	"10.02"	"299.38"	"5.75"	"1"	"2"	""	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf15996"	"25957"	"ENSG00000132424"	"PNISR"	"A8K540; E1P5D2; hsa:25957; Q5T064; Q5T065; Q6P2B4; Q6P2N4; Q6PJ93; Q6PK36; Q7Z640; Q8N2L1; Q8TF00; Q8TF01; Q96K10; Q96SI3; Q96SM5; Q9P076; Q9P0C0; Q9Y4N3"	""	""	"0"	"0"	"150.3"	"101.1"	"128.3"	"147.7"	"119.3"	"100.9"	"163.0"	"11.6"	"419.7"	"376.2"	"778.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15372"	"Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"352"	"39.9"	"6.54"	"451.27"	"5.75"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf19445"	"8667"	"ENSG00000147677"	"EIF3H"	"hsa:8667; O15372"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"Translation factors; VEGFA-VEGFR2 signaling; Measles virus infection; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"10"	"0"	"43.2"	"42.2"	"51.2"	"48.2"	"44.0"	"43.7"	"62.2"	"0.0"	"158.3"	"158.7"	"569.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTD8"	"RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"480"	"50.4"	"9.63"	"227.58"	"5.75"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79171"	"ENSG00000126254"	"RBM42"	"hsa:79171; O00320; Q8N5R7; Q9BTD8; Q9BU66"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"109.7"	"89.0"	"66.3"	"77.9"	"79.5"	"87.1"	"155.3"	"2.1"	"817.7"	"813.1"	"1854.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTX5"	"Ethylmalonyl-CoA decarboxylase OS=Homo sapiens OX=9606 GN=ECHDC1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"4"	"1"	"307"	"33.7"	"8.21"	"460.44"	"5.74"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00378"	"55862"	"ENSG00000093144"	"ECHDC1"	"A6NFJ5; B7Z8S0; E9PEN7; E9PR31; F8W851; hsa:55862; Q5TEF6; Q5TEF7; Q5TEG0; Q5TEG4; Q9NTX5; Q9NZ30; V9HW18"	""	"Fatty acid biosynthesis"	"1"	"0"	"4.0"	"4.4"	"11.7"	"6.7"	"7.2"	"14.8"	"26.2"	"0.9"	"318.9"	"306.6"	"550.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00487"	"26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1"	""	""	"11"	"1"	"1"	"1"	"310"	"34.6"	"6.52"	""	"5.73"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01398, Pf13012"	"10213"	"ENSG00000115233"	"PSMD14"	"B3KNW2; hsa:10213; O00176; O00487"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Metalloprotease DUBs"	"Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"3.5"	"0.0"	"2.4"	"4.4"	"0.0"	"3.7"	"3.8"	"0.7"	"73.0"	"73.5"	"183.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13464"	"Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1354"	"158.1"	"5.90"	"241.78"	"5.72"	"1"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08912"	"6093"	"ENSG00000067900"	"ROCK1"	"B0YJ91; hsa:6093; Q13464; Q2KHM4; Q59GZ4"	"Neutrophil degranulation; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Potential therapeutics for SARS; RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHOB GTPase cycle; RND3 GTPase cycle; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs; RHOBTB1 GTPase cycle; RHOH GTPase cycle; Apoptotic cleavage of cellular proteins"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Leptin signaling pathway; Microtubule cytoskeleton regulation; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Focal adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Gastrin signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; G13 signaling pathway"	"34"	"0"	"3.4"	"4.3"	"4.1"	"4.2"	"1.8"	"3.0"	"4.8"	"1.8"	"58.1"	"57.1"	"167.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H845"	"Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"621"	"68.7"	"7.96"	""	"5.72"	""	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"28976"	"ENSG00000177646"	"ACAD9"	"D3DNB8; hsa:28976; Q8WXX3; Q9H845"	"Complex I biogenesis"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"3"	"0"	"7.4"	"5.8"	"7.4"	"7.4"	"5.4"	"8.2"	"14.1"	"1.0"	"92.9"	"95.8"	"158.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8E8"	"Cysteine-rich protein 2-binding protein OS=Homo sapiens OX=9606 GN=KAT14 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"782"	"88.8"	"6.57"	"642.97"	"5.72"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf13673"	"57325"	"ENSG00000149474"	"KAT14"	"A2A2I5; hsa:57325; Q96GW6; Q96IH3; Q9H8E8; Q9HBF0; Q9UIY5"	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	""	"2"	"0"	"0.0"	"0.0"	"2.8"	"0.0"	"2.7"	"0.0"	"3.2"	"0.0"	"26.7"	"27.3"	"53.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L9B9"	"Endonuclease/exonuclease/phosphatase family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EEPD1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"569"	"62.4"	"8.41"	"294.13"	"5.68"	"1"	"2"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes"	"nucleic acid binding activity"	"Pf12836"	"80820"	"ENSG00000122547"	"EEPD1"	"hsa:80820; Q7L9B9; Q96K64; Q9C0F7"	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"	""	"1"	"0"	"10.2"	"6.3"	"8.0"	"11.4"	"11.3"	"13.1"	"21.5"	"8.3"	"215.8"	"196.3"	"433.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99460"	"26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"953"	"105.8"	"5.39"	"586.41"	"5.67"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01851, Pf13646, Pf18004"	"5707"	"ENSG00000173692"	"PSMD1"	"B8ZZH9; hsa:5707; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9; Q86VU1; Q8IV79; Q99460"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"17.6"	"17.8"	"21.2"	"19.2"	"19.7"	"17.0"	"15.7"	"3.3"	"196.4"	"194.8"	"445.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y617"	"Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"370"	"40.4"	"7.66"	""	"5.67"	""	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00266"	"29968"	"ENSG00000135069"	"PSAT1"	"hsa:29968; Q5T7G5; Q5T7G6; Q96AW2; Q9BQ12; Q9Y617"	"Serine biosynthesis"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Male infertility; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"7"	"0"	"2.5"	"0.0"	"2.4"	"0.0"	"4.7"	"3.2"	"5.8"	"0.0"	"46.7"	"42.6"	"172.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14174"	"Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4"	"0.000"	""	"8"	"1"	"4"	"1"	"115"	"12.5"	"7.88"	"647.90"	"5.66"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"4282"	"ENSG00000240972; ENSG00000276701"	"MIF"	"A5Z1R8; B2R4S3; hsa:4282; P14174; Q2V4Y5; Q6FHV0"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"Adipogenesis; Spinal cord injury"	"5"	"0"	"57.2"	"39.8"	"100.0"	"51.5"	"82.4"	"46.2"	"170.1"	"0.5"	"515.7"	"474.9"	"1122.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95229"	"ZW10 interactor OS=Homo sapiens OX=9606 GN=ZWINT PE=1 SV=2"	""	""	"8"	"1"	"1"	"1"	"277"	"31.3"	"5.15"	""	"5.65"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15556"	"11130"	"ENSG00000122952"	"ZWINT"	"A6NNV6; hsa:11130; O95229; Q0D2I3; Q9BWD0"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43432"	"Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1585"	"176.5"	"5.38"	"389.59"	"5.64"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"8672"	"ENSG00000075151"	"EIF4G3"	"B9EGQ7; hsa:8672; O43432; Q15597; Q504Z1; Q5SWC3; Q8NEN1"	"ISG15 antiviral mechanism"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"3"	"0"	"39.5"	"43.8"	"52.1"	"40.9"	"35.4"	"48.1"	"102.4"	"1.1"	"325.9"	"316.8"	"656.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRX1"	"RNA-binding protein PNO1 OS=Homo sapiens OX=9606 GN=PNO1 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"252"	"27.9"	"9.73"	"648.73"	"5.63"	"1"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	""	""	"56902"	"ENSG00000115946"	"PNO1"	"A8K6Q0; hsa:56902; Q53G13; Q8WVB8; Q9NRX1"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5J9"	"Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1"	"0.000"	""	"13"	"1"	"4"	"1"	"83"	"9.3"	"5.12"	"862.77"	"5.62"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02953"	"26521"	"ENSG00000150779"	"TIMM8B"	"B0YJA5; hsa:26521; Q3KQS9; Q9UN04; Q9Y5J9"	"Mitochondrial protein import"	""	"1"	"0"	"16.8"	"14.6"	"22.4"	"17.1"	"12.6"	"14.2"	"32.2"	"7.6"	"515.3"	"523.1"	"1291.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y530"	"ADP-ribose glycohydrolase OARD1 OS=Homo sapiens OX=9606 GN=OARD1 PE=1 SV=2"	"0.000"	""	"11"	"2"	"4"	"2"	"152"	"17.0"	"8.31"	"673.77"	"5.62"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf01661"	"221443"	"ENSG00000124596"	"OARD1"	"A6NEK4; A8K4H4; hsa:221443; Q96F23; Q9Y530"	""	""	"0"	"0"	"63.2"	"58.4"	"62.0"	"60.3"	"53.5"	"51.9"	"120.2"	"0.0"	"1024.5"	"1096.8"	"1846.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P000"	"COMM domain-containing protein 9 OS=Homo sapiens OX=9606 GN=COMMD9 PE=1 SV=2"	""	""	"11"	"2"	"2"	"2"	"198"	"21.8"	"5.88"	""	"5.62"	""	"2"	"transport;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf07258"	"29099"	"ENSG00000110442"	"COMMD9"	"E9PAN2; hsa:29099; Q96FI2; Q9H0R0; Q9P000"	"Neutrophil degranulation; Neddylation"	""	"2"	"0"	"19.8"	"8.3"	"18.8"	"21.0"	"19.2"	"11.9"	"31.0"	"0.0"	"322.7"	"301.6"	"667.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61599"	"N-alpha-acetyltransferase 20 OS=Homo sapiens OX=9606 GN=NAA20 PE=1 SV=1"	"0.000"	""	"14"	"2"	"4"	"2"	"178"	"20.4"	"5.03"	"692.45"	"5.61"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"51126"	"ENSG00000173418"	"NAA20"	"A6NHA3; B2R4G4; hsa:51126; P61599; Q5TFT7; Q9D7H8; Q9H0Y4; Q9NQH6; Q9Y6D2"	""	"Metapathway biotransformation Phase I and II"	"1"	"0"	"10.6"	"5.3"	"12.6"	"11.7"	"18.8"	"14.6"	"24.3"	"0.0"	"236.0"	"234.7"	"552.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A35"	"39S ribosomal protein L24, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL24 PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"2"	"216"	"24.9"	"9.29"	"276.36"	"5.61"	"1"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf17136"	"79590"	"ENSG00000143314"	"MRPL24"	"D3DVC8; hsa:79590; Q53G65; Q53HT0; Q5SYZ9; Q5SZ00; Q5SZ02; Q96A35; Q96Q70; Q9H7G3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"55.4"	"40.7"	"66.8"	"55.3"	"54.4"	"64.1"	"110.8"	"0.3"	"503.4"	"487.9"	"1034.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2K8"	"eIF-2-alpha kinase GCN2 OS=Homo sapiens OX=9606 GN=EIF2AK4 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"1649"	"186.8"	"6.28"	"296.46"	"5.60"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069, Pf05773, Pf12745, Pf13393"	"440275"	"ENSG00000128829"	"EIF2AK4"	"C9JEC4; hsa:440275; Q69YL7; Q6DC97; Q96GN6; Q9H5K1; Q9NSQ3; Q9NSZ5; Q9P2K8; Q9UJ56"	"Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Measles virus infection"	"2"	"0"	"6.0"	"2.1"	"9.4"	"3.2"	"4.7"	"2.5"	"15.5"	"1.3"	"199.4"	"181.7"	"468.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31483"	"Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"1"	"386"	"42.9"	"7.74"	"533.36"	"5.60"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7072"	"ENSG00000116001"	"TIA1"	"hsa:7072; P31483; Q53SS9; Q96B58"	"FGFR2 alternative splicing"	""	"1"	"0"	"100.8"	"82.2"	"88.7"	"97.0"	"89.3"	"95.3"	"127.9"	"0.0"	"258.4"	"293.9"	"282.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62917"	"60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2"	"0.000"	""	"10"	"4"	"7"	"4"	"257"	"28.0"	"11.03"	"1112.84"	"5.58"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00181, Pf03947"	"6132"	"ENSG00000161016"	"RPL8"	"A8K094; D3DWN2; hsa:6132; P25120; P62917; Q567Q7; Q969V7; Q9BWQ9"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"272.6"	"239.7"	"289.9"	"253.6"	"200.1"	"271.1"	"1400.4"	"0.0"	"2540.7"	"2648.8"	"4159.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVS4"	"Serine/threonine-protein kinase RIO2 OS=Homo sapiens OX=9606 GN=RIOK2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"552"	"63.2"	"5.94"	"319.15"	"5.58"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf01163, Pf09202"	"55781"	"ENSG00000058729"	"RIOK2"	"D6RDI3; hsa:55781; Q9BVS4; Q9NUT0"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"2.5"	"0.0"	"3.4"	"0.0"	"0.0"	"0.0"	"8.9"	"0.0"	"28.8"	"30.9"	"63.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IU81"	"Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"584"	"61.6"	"8.18"	""	"5.58"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00097, Pf11261"	"26145"	"ENSG00000170604"	"IRF2BP1"	"hsa:26145; Q53EL7; Q6DC95; Q8IU81; Q9BRZ9; Q9Y4P4"	""	""	"0"	"0"	"17.5"	"10.6"	"18.1"	"17.2"	"13.5"	"28.2"	"48.5"	"0.0"	"530.9"	"539.3"	"997.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00716"	"Transcription factor E2F3 OS=Homo sapiens OX=9606 GN=E2F3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"465"	"49.1"	"5.44"	"534.17"	"5.57"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02319, Pf16421"	"1871"	"ENSG00000112242"	"E2F3"	"hsa:1871; O00716; Q15000; Q68DT0; Q9BZ44"	"Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3)"	"Cell cycle; Metastatic brain tumor; B cell receptor signaling pathway; Retinoblastoma gene in cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; G1 to S cell cycle control; Small cell lung cancer; Melanoma; Nephrotic syndrome"	"17"	"0"	"3.7"	"0.0"	"2.4"	"0.0"	"0.0"	"4.3"	"6.8"	"0.0"	"123.0"	"144.8"	"355.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13177"	"Serine/threonine-protein kinase PAK 2 OS=Homo sapiens OX=9606 GN=PAK2 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"524"	"58.0"	"5.96"	"357.03"	"5.57"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00786"	"5062"	"ENSG00000180370"	"PAK2"	"hsa:5062; Q13154; Q13177; Q6ISC3"	"Regulation of activated PAK-2p34 by proteasome mediated degradation; MAPK6/MAPK4 signaling; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOV GTPase cycle; Smooth Muscle Contraction; FCERI mediated MAPK activation; Generation of second messenger molecules; Regulation of PAK-2p34 activity by PS-GAP/RHG10; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; Ephrin signaling; Sema3A PAK dependent Axon repulsion; RHO GTPases activate PAKs; VEGFR2 mediated vascular permeability; Activation of RAC1; RHOH GTPase cycle; CD209 (DC-SIGN) signaling; CD28 dependent Vav1 pathway; Nef and signal transduction; Stimulation of the cell death response by PAK-2p34"	"Integrin-mediated cell adhesion; Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ras signaling; Pancreatic adenocarcinoma pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Neural crest cell migration during development; Neural crest cell migration in cancer; 3q29 copy number variation syndrome; Pleural mesothelioma; Regulation of actin cytoskeleton; ErbB signaling pathway"	"43"	"0"	"0.0"	"3.5"	"3.8"	"4.1"	"4.9"	"1.8"	"7.6"	"2.7"	"163.9"	"169.7"	"496.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99442"	"Translocation protein SEC62 OS=Homo sapiens OX=9606 GN=SEC62 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"399"	"45.8"	"7.12"	"690.24"	"5.56"	"2"	"2"	"transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03839"	"7095"	"ENSG00000008952"	"SEC62"	"D3DNQ0; hsa:7095; O00682; O00729; Q99442"	""	""	"0"	"0"	"16.1"	"17.8"	"25.6"	"22.5"	"20.7"	"19.5"	"30.1"	"0.0"	"605.2"	"643.3"	"1573.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5VZE5"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1"	""	""	"3"	"2"	"2"	"2"	"725"	"83.6"	"7.05"	""	"5.53"	""	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf04112"	"60560"	"ENSG00000135040"	"NAA35"	"hsa:60560; Q5VZE5; Q5VZE6; Q9H631; Q9H703"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	"3.0"	"2.1"	"3.2"	"2.7"	"0.0"	"0.0"	"5.6"	"2.9"	"93.1"	"76.3"	"225.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61218"	"DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Homo sapiens OX=9606 GN=POLR2F PE=1 SV=1"	"0.000"	""	"26"	"2"	"2"	"2"	"127"	"14.5"	"4.22"	"322.26"	"5.53"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01192"	"5435"	"ENSG00000100142"	"POLR2F"	"hsa:5435; P41584; P61218; Q6IAY3"	"mRNA Splicing - Major Pathway; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"56"	"0"	"29.2"	"20.1"	"42.2"	"20.1"	"27.6"	"31.8"	"127.8"	"5.7"	"741.6"	"736.5"	"1039.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03188"	"Centromere protein C OS=Homo sapiens OX=9606 GN=CENPC PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"943"	"106.8"	"9.39"	"583.48"	"5.53"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11699, Pf15620, Pf15622"	"1060"	"ENSG00000145241"	"CENPC"	"hsa:1060; Q03188; Q6PIR0; Q8IW27; Q9P0M5"	"Separation of Sister Chromatids; Deposition of new CENPA-containing nucleosomes at the centromere; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"7"	"0"	"16.9"	"8.9"	"13.4"	"10.7"	"12.7"	"9.0"	"30.7"	"2.2"	"135.3"	"107.4"	"217.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TF76"	"Serine/threonine-protein kinase haspin OS=Homo sapiens OX=9606 GN=HASPIN PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"798"	"88.4"	"9.16"	""	"5.52"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf12330"	"83903"	"ENSG00000177602"	"HASPIN"	"hsa:83903; Q5U5K3; Q8TF76; Q96MN1; Q9BXS7"	""	""	"0"	"0"	"7.9"	"8.9"	"10.1"	"6.7"	"6.5"	"8.9"	"16.2"	"0.8"	"145.0"	"141.7"	"323.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y371"	"Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"2"	"2"	"365"	"40.8"	"6.04"	"383.56"	"5.52"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03114, Pf14604"	"51100"	"ENSG00000097033"	"SH3GLB1"	"B4E182; hsa:51100; Q5H8U5; Q9H3Z0; Q9NR47; Q9NYA9; Q9Y371"	""	"Nanoparticle triggered autophagic cell death"	"1"	"0"	"5.6"	"2.3"	"12.9"	"7.0"	"10.2"	"9.2"	"22.6"	"2.3"	"241.8"	"238.9"	"476.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08195"	"4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"630"	"68.0"	"5.01"	"506.88"	"5.52"	"1"	"2"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00128, Pf16028"	"6520"	"ENSG00000168003"	"SLC3A2"	"hsa:6520; J3KPF3; P08195; Q13543"	"Tryptophan catabolism; Basigin interactions; Amino acid transport across the plasma membrane; Defective SLC7A7 causes lysinuric protein intolerance (LPI)"	"mRNA, protein, and metabolite inducation pathway by cyclosporin A; Ferroptosis; Proximal tubule transport; Pleural mesothelioma"	"8"	"0"	"4.0"	"0.0"	"2.4"	"4.2"	"0.0"	"0.0"	"10.3"	"1.2"	"71.0"	"57.0"	"123.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61024"	"Cyclin-dependent kinases regulatory subunit 1 OS=Homo sapiens OX=9606 GN=CKS1B PE=1 SV=1"	"0.000"	""	"20"	"1"	"2"	"1"	"79"	"9.7"	"8.94"	"563.93"	"5.49"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01111"	"1163"	"ENSG00000173207"	"CKS1B"	"hsa:1163; P33551; P61024"	"SCF(Skp2)-mediated degradation of p27/p21; Cyclin D associated events in G1"	"Small cell lung cancer"	"3"	"0"	"24.6"	"35.0"	"17.0"	"26.4"	"13.7"	"33.4"	"124.8"	"0.0"	"1100.6"	"1235.0"	"2057.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49916"	"DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1009"	"112.8"	"9.01"	"1223.45"	"5.49"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00645, Pf01068, Pf04675, Pf04679, Pf16759"	"3980"	"ENSG00000005156"	"LIG3"	"E5KLB5; E5KLB6; hsa:3980; P49916; Q16714; Q6NVK3"	"HDR through MMEJ (alt-NHEJ); Gap-filling DNA repair synthesis and ligation in TC-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; Resolution of AP sites via the single-nucleotide replacement pathway"	"Base excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 17q12 copy number variation syndrome"	"9"	"0"	"50.3"	"35.2"	"46.0"	"48.0"	"42.2"	"53.3"	"97.2"	"2.1"	"832.7"	"860.9"	"2024.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46109"	"Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"303"	"33.8"	"6.74"	"363.30"	"5.47"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf07653"	"1399"	"ENSG00000099942"	"CRKL"	"A8KA44; D3DX35; hsa:1399; P46109"	"Downstream signal transduction; Regulation of signaling by CBL; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1; MET receptor recycling"	"Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; Chemokine signaling pathway; EGF/EGFR signaling pathway; 22q11.2 copy number variation syndrome; IL-2 signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"21"	"0"	"61.3"	"40.1"	"53.9"	"53.8"	"47.7"	"32.5"	"67.0"	"0.0"	"143.8"	"106.0"	"240.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13451"	"Peptidyl-prolyl cis-trans isomerase FKBP5 OS=Homo sapiens OX=9606 GN=FKBP5 PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"457"	"51.2"	"5.90"	""	"5.47"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00254, Pf00515"	"2289"	"ENSG00000096060"	"FKBP5"	"F5H7R1; hsa:2289; Q13451; Q59EB8; Q5TGM6"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; ESR-mediated signaling; MECP2 regulates neuronal receptors and channels"	"Androgen receptor network in prostate cancer; Farnesoid X receptor pathway; Nuclear receptors meta-pathway; MECP2 and associated Rett syndrome"	"7"	"0"	"4.1"	"2.5"	"6.9"	"6.0"	"5.9"	"2.8"	"6.6"	"0.0"	"117.2"	"123.4"	"415.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14789"	"Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"1"	"3259"	"375.8"	"5.00"	"223.76"	"5.46"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi"	"nucleic acid binding activity"	""	"2804"	"ENSG00000173230"	"GOLGB1"	"B2ZZ91; D3DN92; E7EP74; F1T0J2; hsa:2804; Q14398; Q14789"	"Golgi Associated Vesicle Biogenesis; COPI-mediated anterograde transport; Signaling by FLT3 fusion proteins"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWF6"	"Protein DENND6A OS=Homo sapiens OX=9606 GN=DENND6A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"608"	"69.5"	"8.27"	"553.05"	"5.46"	"1"	"1"	"other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf08616, Pf09794"	"201627"	"ENSG00000174839"	"DENND6A"	"hsa:201627; Q7Z5T4; Q8IWF6; Q8N235; Q8TEG8"	"RAB GEFs exchange GTP for GDP on RABs"	""	"1"	"0"	"11.7"	"10.2"	"13.7"	"13.2"	"11.7"	"14.9"	"26.5"	"0.9"	"185.7"	"181.2"	"349.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6VY07"	"Phosphofurin acidic cluster sorting protein 1 OS=Homo sapiens OX=9606 GN=PACS1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"963"	"104.8"	"7.74"	"302.71"	"5.44"	"1"	"2"	"other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf10254"	"55690"	"ENSG00000175115"	"PACS1"	"hsa:55690; Q6PJY6; Q6PKB6; Q6VY07; Q7Z590; Q7Z5W4; Q8N8K6; Q96MW0; Q9NW92; Q9ULP5"	"Nef mediated downregulation of MHC class I complex cell surface expression"	""	"1"	"0"	"21.6"	"17.6"	"24.0"	"15.7"	"23.2"	"19.6"	"39.3"	"0.8"	"383.4"	"408.1"	"732.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O94874"	"E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2"	""	""	"4"	"2"	"2"	"2"	"794"	"89.5"	"6.79"	""	"5.44"	""	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf09743"	"23376"	"ENSG00000014123"	"UFL1"	"A0PJ53; B4DJ57; C0H5X5; hsa:23376; O94874; Q8N765; Q9NTQ0"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"13.0"	"8.8"	"24.7"	"15.8"	"18.0"	"19.3"	"102.4"	"1.2"	"706.1"	"709.2"	"1490.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H0E9"	"Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1235"	"135.3"	"4.60"	""	"5.43"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00439"	"10902"	"ENSG00000112983"	"BRD8"	"hsa:10902; O43178; Q15355; Q58AB0; Q59GN0; Q969M9; Q9H0E9"	"HATs acetylate histones"	""	"1"	"0"	"20.8"	"17.0"	"21.9"	"16.7"	"22.8"	"21.3"	"39.6"	"0.0"	"226.0"	"233.1"	"512.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49643"	"DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"509"	"58.8"	"7.91"	"559.74"	"5.42"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf04104"	"5558"	"ENSG00000146143"	"PRIM2"	"hsa:5558; P49643; Q53FJ8; Q6P1Q7; Q8WVL2; Q9H413"	"Polymerase switching on the C-strand of the telomere; Polymerase switching; Activation of the pre-replicative complex; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Telomere C-strand synthesis initiation; DNA replication initiation; Removal of the Flap Intermediate"	"Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"12"	"0"	"18.4"	"10.6"	"11.8"	"12.0"	"11.1"	"12.3"	"24.8"	"3.4"	"259.9"	"254.8"	"461.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03701"	"CCAAT/enhancer-binding protein zeta OS=Homo sapiens OX=9606 GN=CEBPZ PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1054"	"120.9"	"5.94"	"605.29"	"5.42"	"2"	"2"	"other biological processes"	"nucleus"	"other molecular function"	"Pf03914"	"10153"	"ENSG00000115816"	"CEBPZ"	"hsa:10153; Q03701; Q8NE75"	""	"Gastric cancer network 2"	"1"	"0"	"17.5"	"9.5"	"17.0"	"11.8"	"12.8"	"13.9"	"34.0"	"0.2"	"198.7"	"220.3"	"403.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96DH6"	"RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"328"	"35.2"	"8.48"	""	"5.42"	""	"1"	"developmental processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"124540"	"ENSG00000153944"	"MSI2"	"hsa:124540; Q7Z6M7; Q8N9T4; Q96DH6"	"RHOBTB2 GTPase cycle"	""	"1"	"0"	"18.6"	"17.9"	"16.7"	"16.2"	"10.3"	"10.9"	"54.2"	"1.9"	"128.6"	"123.8"	"192.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT06"	"Centrosome-associated protein 350 OS=Homo sapiens OX=9606 GN=CEP350 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"3117"	"350.7"	"6.33"	"607.39"	"5.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14309"	"9857"	"ENSG00000135837"	"CEP350"	"hsa:9857; O75068; Q5VT06; Q8TDK3; Q8WY20"	""	"3q29 copy number variation syndrome"	"1"	"0"	"4.5"	"6.8"	"9.3"	"4.4"	"7.8"	"5.3"	"12.9"	"2.9"	"84.9"	"68.0"	"145.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1X6"	"UPF0598 protein C8orf82 OS=Homo sapiens OX=9606 GN=C8orf82 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"216"	"23.9"	"9.14"	"652.74"	"5.41"	"2"	"2"	""	""	""	"Pf14956"	"414919"	"ENSG00000213563"	"C8orf82"	"hsa:414919; Q6GMR2; Q6P1X6; Q6P2Q7"	""	""	"0"	"0"	"15.8"	"13.5"	"24.0"	"14.5"	"22.0"	"23.8"	"33.5"	"0.0"	"333.7"	"358.4"	"890.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8G2"	"Caspase activity and apoptosis inhibitor 1 OS=Homo sapiens OX=9606 GN=CAAP1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"361"	"38.3"	"4.72"	"250.28"	"5.41"	"1"	"2"	"other biological processes"	""	""	"Pf15335"	"79886"	"ENSG00000120159"	"CAAP1"	"B4DWT4; D3DRK4; hsa:79886; Q5VY32; Q6IPE6; Q96C59; Q9H8G2"	""	"Acute viral myocarditis"	"1"	"0"	"43.5"	"22.2"	"44.8"	"49.8"	"44.4"	"41.5"	"68.2"	"0.0"	"791.8"	"677.8"	"1556.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W92"	"Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"1011"	"114.0"	"5.55"	"273.88"	"5.41"	"1"	"2"	"cell adhesion;cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8496"	"ENSG00000110841"	"PPFIBP1"	"hsa:8496; O75336; Q86W92; Q86X70; Q9NY03; Q9ULJ0"	"Signaling by ALK fusions and activated point mutants; Receptor-type tyrosine-protein phosphatases"	""	"2"	"0"	"22.3"	"25.5"	"23.5"	"24.7"	"21.8"	"25.2"	"51.6"	"4.5"	"188.7"	"195.1"	"285.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6IA86"	"Elongator complex protein 2 OS=Homo sapiens OX=9606 GN=ELP2 PE=1 SV=2"	""	""	"2"	"2"	"2"	"2"	"826"	"92.4"	"5.96"	""	"5.41"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"55250"	"ENSG00000134759"	"ELP2"	"A8KAI6; B4DTG0; B4DXP0; E7EP23; E9PCX0; hsa:55250; Q53GZ0; Q687Y8; Q6IA86; Q8N5C2; Q96GV4; Q96PI7; Q9H9N0; Q9NV81"	"HATs acetylate histones"	""	"1"	"0"	"4.0"	"2.1"	"7.0"	"3.4"	"9.9"	"7.2"	"4.1"	"0.9"	"544.1"	"618.8"	"1642.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N1G0"	"Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"1237"	"129.4"	"8.19"	""	"5.40"	""	"1"	""	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf16622"	"57592"	"ENSG00000143373"	"ZNF687"	"D3DV17; hsa:57592; Q68DQ8; Q8N1G0; Q9H937; Q9P2A7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09543"	"2',3'-cyclic-nucleotide 3'-phosphodiesterase OS=Homo sapiens OX=9606 GN=CNP PE=1 SV=2"	"0.000"	""	"9"	"3"	"3"	"2"	"421"	"47.5"	"9.07"	"224.60"	"5.40"	"1"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05881, Pf13671"	"1267"	"ENSG00000173786"	"CNP"	"hsa:1267; P09543"	""	"Glial cell differentiation; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; FGFR3 signaling in chondrocyte proliferation and terminal differentiation"	"4"	"0"	"10.2"	"8.3"	"15.2"	"10.2"	"10.0"	"10.3"	"33.7"	"0.0"	"518.5"	"506.8"	"1090.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD1"	"39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"178"	"20.7"	"9.16"	"628.62"	"5.40"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"28998"	"ENSG00000172172"	"MRPL13"	"B2R4R8; hsa:28998; Q9BYD1; Q9UI04"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"8.6"	"8.8"	"8.2"	"5.8"	"9.6"	"11.3"	"17.6"	"0.7"	"61.3"	"62.2"	"109.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15642"	"Cdc42-interacting protein 4 OS=Homo sapiens OX=9606 GN=TRIP10 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"601"	"68.3"	"5.73"	"250.39"	"5.39"	"1"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf00611"	"9322"	"ENSG00000125733"	"TRIP10"	"B2R8A6; B7WP22; D6W645; hsa:9322; O15184; Q15642; Q53G22; Q5TZN1; Q6FI24; Q8NFL1; Q8TCY1; Q8TDX3; Q96RJ1"	"RHOQ GTPase cycle; Clathrin-mediated endocytosis"	"Angiopoietin-like protein 8 regulatory pathway"	"3"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.7"	"0.0"	"23.9"	"28.4"	"71.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P18031"	"Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1"	""	""	"4"	"2"	"2"	"2"	"435"	"49.9"	"6.27"	""	"5.39"	""	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5770"	"ENSG00000196396"	"PTPN1"	"hsa:5770; P18031; Q5TGD8; Q9BQV9; Q9NQQ4"	"Growth hormone receptor signaling; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Negative regulation of MET activity; Insulin receptor recycling; Integrin signaling; MECP2 regulates neuronal receptors and channels; PTK6 Down-Regulation"	"Leptin signaling pathway; Prolactin signaling pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"14"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.2"	"0.0"	"1.4"	"0.0"	"90.9"	"79.2"	"224.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50213"	"Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1"	"0.000"	""	"5"	"2"	"5"	"2"	"366"	"39.6"	"6.92"	"611.78"	"5.39"	"1"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00180"	"3419"	"ENSG00000166411"	"IDH3A"	"D3DW83; hsa:3419; P50213; Q9H3X0"	"Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Metabolic reprogramming in colon cancer; TCA cycle (aka Krebs or citric acid cycle)"	"4"	"0"	"67.9"	"45.1"	"83.6"	"65.0"	"63.4"	"71.8"	"99.9"	"0.0"	"834.5"	"906.4"	"2397.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWF3"	"RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"364"	"40.3"	"7.08"	"608.14"	"5.38"	"2"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00098"	"5936"	"ENSG00000173933"	"RBM4"	"B3KUN0; B4E1U0; E7EQS3; hsa:5936; O02916; Q4VC48; Q6P1P2; Q8WU85; Q9BWF3"	"Circadian Clock"	""	"1"	"0"	"95.4"	"54.6"	"88.5"	"85.1"	"84.3"	"70.0"	"167.3"	"0.0"	"981.8"	"1040.1"	"2019.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95373"	"Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1038"	"119.4"	"4.82"	"307.48"	"5.38"	"1"	"2"	"stress response;transport;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf03810, Pf08506"	"10527"	"ENSG00000205339"	"IPO7"	"A6NNM5; B2R786; hsa:10527; O95373; Q1RMF7; Q9H177; Q9NTE3"	""	""	"0"	"0"	"2.9"	"2.3"	"0.0"	"0.0"	"0.0"	"0.0"	"4.7"	"2.8"	"114.7"	"118.9"	"289.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5X2"	"Sorting nexin-8 OS=Homo sapiens OX=9606 GN=SNX8 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"465"	"52.5"	"7.39"	"268.23"	"5.38"	"1"	"2"	"transport"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00787, Pf19566"	"29886"	"ENSG00000106266"	"SNX8"	"A4D207; hsa:29886; Q96I67; Q9Y5X2"	""	""	"0"	"0"	"4.1"	"0.0"	"3.7"	"7.4"	"4.0"	"4.5"	"10.3"	"0.7"	"86.1"	"110.1"	"217.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P49674"	"Casein kinase I isoform epsilon OS=Homo sapiens OX=9606 GN=CSNK1E PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"416"	"47.3"	"9.66"	""	"5.35"	""	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"102800317; 1454"	"ENSG00000213923"	"CSNK1E"	"hsa:102800317; hsa:1454; P49674"	"Major pathway of rRNA processing in the nucleolus and cytosol; WNT mediated activation of DVL; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Circadian Clock"	"Alzheimer's disease and miRNA effects; Melatonin metabolism and effects; Wnt signaling pathway; Wnt signaling pathway and pluripotency; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma; Alzheimer's disease"	"20"	"0"	"21.7"	"13.2"	"19.9"	"18.5"	"18.5"	"20.1"	"44.0"	"0.3"	"327.0"	"371.5"	"1050.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCN4"	"E3 ubiquitin-protein ligase RNF169 OS=Homo sapiens OX=9606 GN=RNF169 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"708"	"77.1"	"9.10"	"642.00"	"5.35"	"2"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13920"	"254225"	"ENSG00000166439"	"RNF169"	"hsa:254225; Q6N015; Q8NCN4"	""	""	"0"	"0"	"31.4"	"26.9"	"28.2"	"26.0"	"22.9"	"29.3"	"62.8"	"0.0"	"231.6"	"210.6"	"437.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14770"	"Homeobox protein Meis2 OS=Homo sapiens OX=9606 GN=MEIS2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"477"	"51.8"	"6.40"	"396.11"	"5.33"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05920, Pf16493"	"4212"	"ENSG00000134138"	"MEIS2"	"A6NJI5; A8MWD5; B3KP98; B3KPQ6; hsa:4212; O14770; Q96DI2; Q96KI4; Q96KI5; Q9NRS1; Q9NRS2; Q9NRS3"	""	""	"0"	"0"	"6.3"	"2.9"	"5.8"	"7.1"	"0.0"	"3.1"	"7.5"	"1.3"	"39.3"	"43.7"	"84.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKA9"	"Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"5"	"1"	"531"	"57.5"	"8.66"	"1347.35"	"5.33"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"58155"	"ENSG00000117569"	"PTBP2"	"hsa:58155; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76; Q9UKA9"	""	"Genes targeted by miRNAs in adipocytes; mRNA processing"	"2"	"0"	"16.3"	"11.4"	"21.2"	"15.8"	"12.5"	"12.7"	"30.8"	"0.0"	"171.0"	"180.4"	"382.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43181"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS4 PE=1 SV=1"	""	""	"15"	"1"	"1"	"1"	"175"	"20.1"	"10.30"	""	"5.32"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf04800"	"4724"	"ENSG00000164258"	"NDUFS4"	"hsa:4724; O43181; Q9BS69"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"2.0"	"0.0"	"2.9"	"2.8"	"3.9"	"5.4"	"7.2"	"4.3"	"52.6"	"47.4"	"90.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJV3"	"Probable E3 ubiquitin-protein ligase MID2 OS=Homo sapiens OX=9606 GN=MID2 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"1"	"735"	"83.2"	"7.39"	"299.03"	"5.32"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00622, Pf00643, Pf13445, Pf18568"	"11043"	"ENSG00000080561"	"MID2"	"A6NEL8; A6PVI5; hsa:11043; Q5JYF5; Q8WWK1; Q9UJR9; Q9UJV3"	""	""	"0"	"0"	"0.0"	"2.5"	"2.6"	"0.0"	"3.0"	"0.0"	"14.7"	"6.5"	"54.0"	"44.2"	"86.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15347"	"High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4"	"0.000"	""	"15"	"2"	"3"	"2"	"200"	"23.0"	"8.37"	"1192.39"	"5.31"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505, Pf09011"	"3149"	"ENSG00000029993"	"HMGB3"	"hsa:3149; O15347; O95556; Q6NS40"	""	""	"0"	"0"	"43.9"	"39.5"	"39.6"	"44.4"	"46.8"	"41.0"	"82.6"	"0.0"	"554.6"	"581.5"	"1275.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q70E73"	"Ras-associated and pleckstrin homology domains-containing protein 1 OS=Homo sapiens OX=9606 GN=RAPH1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1250"	"135.2"	"8.85"	"470.70"	"5.30"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00169, Pf00788"	"65059"	"ENSG00000173166"	"RAPH1"	"hsa:65059; Q70E73; Q96Q37; Q9C0I2"	""	""	"0"	"0"	"0.0"	"1.9"	"2.4"	"0.0"	"2.6"	"0.0"	"7.3"	"0.6"	"55.0"	"59.6"	"116.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60220"	"Mitochondrial import inner membrane translocase subunit Tim8 A OS=Homo sapiens OX=9606 GN=TIMM8A PE=1 SV=1"	""	""	"29"	"2"	"2"	"2"	"97"	"11.0"	"5.16"	""	"5.29"	""	"2"	"cell organization and biogenesis;transport;developmental processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"1678"	"ENSG00000126953"	"TIMM8A"	"B2R5A6; hsa:1678; O60220; Q6IRW6"	"Mitochondrial protein import"	""	"1"	"0"	"30.1"	"23.7"	"31.0"	"24.9"	"21.8"	"25.1"	"44.9"	"1.4"	"428.3"	"428.1"	"1010.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TAD8"	"Smad nuclear-interacting protein 1 OS=Homo sapiens OX=9606 GN=SNIP1 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"396"	"45.8"	"9.99"	""	"5.28"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00498"	"79753"	"ENSG00000163877"	"SNIP1"	"hsa:79753; Q8TAD8; Q96SP9; Q9H9T7"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"14.2"	"11.8"	"15.8"	"11.5"	"10.7"	"12.3"	"27.3"	"1.3"	"186.9"	"203.9"	"479.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZYL4"	"General transcription factor IIH subunit 5 OS=Homo sapiens OX=9606 GN=GTF2H5 PE=1 SV=1"	"0.000"	""	"21"	"1"	"2"	"1"	"71"	"8.0"	"4.65"	"466.26"	"5.26"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf06331"	"404672"	"ENSG00000272047"	"GTF2H5"	"hsa:404672; Q0P5V8; Q6ZYL4"	"NoRC negatively regulates rRNA expression; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"32"	"0"	"3.3"	"4.2"	"6.9"	"6.5"	"3.1"	"3.7"	"15.4"	"0.0"	"243.6"	"211.8"	"378.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Q8"	"General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"519"	"59.5"	"6.90"	"611.59"	"5.26"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09734, Pf17682"	"9328"	"ENSG00000148308"	"GTF3C5"	"A6NI44; A6NJB9; hsa:9328; Q5T7U2; Q5T7U3; Q8N2U7; Q8N857; Q96GD9; Q9H4P2; Q9Y5Q8"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	"0.0"	"3.7"	"0.0"	"0.0"	"2.8"	"0.0"	"3.0"	"0.0"	"53.4"	"61.5"	"211.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q12830"	"Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"3046"	"338.1"	"6.54"	""	"5.25"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf02791, Pf15613"	"2186"	"ENSG00000171634"	"BPTF"	"hsa:2186; Q12830; Q6NX67; Q7Z7D6; Q9UIG2"	""	"Endoderm differentiation; 16p11.2 proximal deletion syndrome"	"2"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"39.6"	"48.6"	"121.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15054"	"DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"466"	"51.4"	"9.35"	"558.34"	"5.25"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf09507"	"10714"	"ENSG00000077514"	"POLD3"	"B7ZAI6; hsa:10714; Q15054; Q32MZ9; Q32N00"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"Homologous recombination; Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"26"	"0"	"27.9"	"17.0"	"27.8"	"20.8"	"21.9"	"24.7"	"47.1"	"1.8"	"359.5"	"344.6"	"688.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW08"	"DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2"	"0.000"	""	"1"	"1"	"3"	"1"	"1133"	"127.7"	"8.50"	"253.13"	"5.25"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"55703"	"ENSG00000013503"	"POLR3B"	"A8K6H0; B3KV73; F5H1E6; hsa:55703; Q9NW08; Q9NW59"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway"	"10"	"0"	"97.2"	"39.5"	"227.9"	"359.7"	"152.0"	"758.7"	"285.3"	"0.0"	"239.1"	"223.2"	"445.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A5YKK6"	"CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"2376"	"266.8"	"7.11"	""	"5.25"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04054, Pf12842, Pf16415, Pf16417, Pf16418"	"23019"	"ENSG00000125107"	"CNOT1"	"A5YKK6; hsa:23019; Q68DX7; Q7Z3K2; Q8IWB8; Q8TB53; Q9BVZ6; Q9UFR8; Q9UI27; Q9Y2L0"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"Ciliary landscape"	"3"	"0"	"4.0"	"3.7"	"10.5"	"5.6"	"4.6"	"5.3"	"9.6"	"2.0"	"82.6"	"80.9"	"199.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB8"	"ATP-dependent RNA helicase SUPV3L1, mitochondrial OS=Homo sapiens OX=9606 GN=SUPV3L1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"786"	"87.9"	"7.99"	"458.27"	"5.24"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf12513, Pf18114, Pf18147"	"6832"	"ENSG00000156502"	"SUPV3L1"	"A8K301; hsa:6832; O43630; Q8IYB8"	""	""	"0"	"0"	"59.6"	"60.3"	"66.9"	"61.9"	"61.3"	"66.7"	"117.5"	"0.0"	"451.0"	"430.4"	"828.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14258"	"E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"630"	"70.9"	"8.09"	"530.86"	"5.23"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00622, Pf13445, Pf13765"	"7706"	"ENSG00000121060"	"TRIM25"	"hsa:7706; Q14258"	"SARS-CoV-1 activates/modulates innate immune responses; ISG15 antiviral mechanism; Interferon gamma signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Termination of translesion DNA synthesis; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"Novel intracellular components of RIG-I-like receptor pathway; Cytosolic DNA-sensing pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; 1p36 copy number variation syndrome"	"16"	"0"	"15.6"	"8.8"	"11.9"	"10.6"	"18.3"	"14.9"	"31.3"	"2.2"	"268.5"	"262.0"	"578.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NY61"	"Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"560"	"63.1"	"4.94"	"441.80"	"5.23"	"1"	"1"	"cell adhesion;stress response;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08164, Pf13339"	"26574"	"ENSG00000275700; ENSG00000276072"	"AATF"	"A6NCJ6; B3KQ26; hsa:26574; Q9NY61; Q9P0A4; Q9UNX5"	"NRAGE signals death through JNK"	"17q12 copy number variation syndrome"	"2"	"0"	"7.5"	"3.7"	"7.8"	"7.5"	"11.0"	"7.9"	"22.0"	"0.0"	"242.9"	"234.6"	"477.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBB9"	"Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"837"	"96.8"	"5.67"	"495.21"	"5.23"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"extracellular matrix;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01585, Pf07842, Pf12457"	"24144"	"ENSG00000100109"	"TFIP11"	"hsa:24144; O95908; Q20WL0; Q5H8V8; Q9UBB9; Q9UGV7; Q9Y2Q8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"5.5"	"2.8"	"12.0"	"5.9"	"7.6"	"6.7"	"17.9"	"0.0"	"275.2"	"285.6"	"650.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09493"	"Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"284"	"32.7"	"4.74"	"621.05"	"5.22"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7168"	"ENSG00000140416"	"TPM1"	"B7Z5T7; D9YZV2; D9YZV3; D9YZV8; hsa:7168; P09493; P09494; P10469; Q6DV89; Q6DV90; Q7Z6L8; Q86W64; Q96IK2; Q9UCI1; Q9UCI2; Q9UCY9; Q9Y427"	"Smooth Muscle Contraction; Striated Muscle Contraction"	"Vitamin D receptor pathway; Striated muscle contraction pathway"	"4"	"0"	"50.0"	"33.1"	"59.9"	"65.6"	"50.5"	"58.8"	"121.4"	"0.0"	"873.0"	"833.7"	"1608.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAS0"	"Protein Njmu-R1 OS=Homo sapiens OX=9606 GN=C17orf75 PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"396"	"44.6"	"5.03"	"355.08"	"5.22"	"1"	"2"	"cell organization and biogenesis;transport"	"ER/Golgi;other cell component"	""	"Pf15053"	"64149"	"ENSG00000108666"	"C17orf75"	"hsa:64149; Q7Z2H4; Q9HAS0"	""	""	"0"	"0"	"12.6"	"7.5"	"17.1"	"12.5"	"22.4"	"18.2"	"28.9"	"0.6"	"310.4"	"307.4"	"734.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y388"	"RNA-binding motif protein, X-linked 2 OS=Homo sapiens OX=9606 GN=RBMX2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"322"	"37.3"	"9.83"	"611.74"	"5.22"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;ER/Golgi;nucleus"	""	"Pf00076"	"51634"	"ENSG00000134597"	"RBMX2"	"A8K9Z0; hsa:51634; Q5JY82; Q9Y388; Q9Y3I8"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"9.2"	"5.8"	"13.6"	"17.8"	"13.1"	"15.2"	"53.7"	"0.0"	"581.2"	"564.8"	"1264.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI35"	"InaD-like protein OS=Homo sapiens OX=9606 GN=PATJ PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1801"	"196.2"	"4.94"	"557.96"	"5.21"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf00595, Pf09045"	""	"ENSG00000132849"	"PATJ"	"O15249; O43742; O60833; Q5VUA5; Q5VUA6; Q5VUA7; Q5VUA8; Q5VUA9; Q5VUB0; Q8NI35; Q8WU78; Q9H3N9"	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction"	""	"2"	"0"	"50.7"	"53.2"	"63.5"	"58.8"	"66.6"	"55.6"	"63.3"	"0.0"	"527.4"	"542.6"	"1501.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14744"	"Protein arginine N-methyltransferase 5 OS=Homo sapiens OX=9606 GN=PRMT5 PE=1 SV=4"	""	""	"4"	"1"	"1"	"1"	"637"	"72.6"	"6.29"	""	"5.20"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05185, Pf17285, Pf17286"	"10419"	"ENSG00000100462"	"PRMT5"	"A8MTP3; A8MZ91; B4DX49; B4DY30; B5BU10; D3DS33; E2QRE7; hsa:10419; O14744; Q6IBR1; Q9UKH1"	"snRNP Assembly; RMTs methylate histone arginines; Regulation of TP53 Activity through Methylation"	"Transcription co-factors SKI and SKIL protein partners; Nitric oxide metabolism in cystic fibrosis"	"5"	"0"	"4.8"	"5.0"	"3.5"	"4.7"	"3.6"	"6.3"	"12.6"	"0.3"	"89.3"	"101.9"	"161.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2R9"	"28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"242"	"28.1"	"9.99"	"501.85"	"5.20"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"51081"	"ENSG00000125445"	"MRPS7"	"B2R9N5; hsa:51081; Q53GD6; Q9Y2R9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"70.8"	"57.5"	"81.6"	"79.6"	"84.5"	"86.6"	"146.4"	"0.1"	"302.7"	"308.8"	"562.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BTE7"	"DCN1-like protein 5 OS=Homo sapiens OX=9606 GN=DCUN1D5 PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"237"	"27.5"	"5.58"	""	"5.20"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03556"	"84259"	"ENSG00000137692"	"DCUN1D5"	"hsa:84259; Q3ZTT2; Q9BTE7"	"Neddylation"	""	"1"	"0"	"10.8"	"4.8"	"11.6"	"10.9"	"11.5"	"9.5"	"15.8"	"0.6"	"80.4"	"77.3"	"152.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6S0"	"3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"2"	"1430"	"160.1"	"8.40"	"542.70"	"5.20"	"2"	"2"	"cell cycle OR cell proliferation;other biological processes"	"ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf01424, Pf04146, Pf04408, Pf07717"	"64848"	"ENSG00000047188"	"YTHDC2"	"B2RP66; hsa:64848; Q9H6S0"	""	""	"0"	"0"	"15.4"	"13.3"	"20.3"	"17.4"	"20.3"	"15.2"	"42.9"	"2.3"	"136.1"	"137.0"	"295.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P81605"	"Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2"	"0.000"	""	"20"	"2"	"4"	"2"	"110"	"11.3"	"6.54"	"541.59"	"5.20"	"2"	"2"	"protein metabolism;stress response;transport;other biological processes"	"non-structural extracellular;other membranes"	"transporter activity;other molecular function"	"Pf15291"	"117159"	"ENSG00000161634"	"DCD"	"A5JHP2; A5JHP3; hsa:117159; P58461; P81605; Q53YJ2"	"Antimicrobial peptides"	""	"1"	"0"	"391.5"	"101.3"	"41.2"	"144.6"	"258.8"	"131.0"	"132.4"	"0.0"	"208.6"	"198.7"	"336.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NQW6"	"Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1124"	"124.1"	"8.07"	""	"5.20"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00169, Pf08174, Pf16018"	"54443"	"ENSG00000011426"	"ANLN"	"hsa:54443; Q5CZ78; Q6NSK5; Q9H8Y4; Q9NQW6; Q9NVN9; Q9NVP0"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"Retinoblastoma gene in cancer; Nephrotic syndrome"	"5"	"0"	"7.2"	"5.4"	"2.9"	"4.7"	"3.7"	"2.5"	"17.5"	"3.1"	"100.3"	"95.0"	"124.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UGY1"	"Nucleolar protein 12 OS=Homo sapiens OX=9606 GN=NOL12 PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"213"	"24.6"	"10.23"	""	"5.20"	""	"1"	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf09805"	"79159"	"ENSG00000273899"	"NOL12"	"hsa:79159; Q9UGY1"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"16.0"	"10.5"	"21.0"	"19.2"	"13.9"	"16.2"	"60.9"	"0.0"	"215.8"	"210.6"	"378.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCD5"	"Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"579"	"65.5"	"9.60"	"784.87"	"5.19"	"3"	"2"	"signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	""	"57727"	"ENSG00000124160"	"NCOA5"	"B2RTV9; E1P5R0; hsa:57727; Q6HA99; Q9H1F2; Q9H2T2; Q9H4Y9; Q9HCD5"	""	""	"0"	"0"	"14.7"	"16.6"	"11.1"	"8.8"	"10.0"	"11.3"	"25.8"	"0.0"	"58.0"	"54.5"	"75.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43686"	"26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"418"	"47.3"	"5.21"	"438.55"	"5.19"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5704"	"ENSG00000013275; ENSG00000281221"	"PSMC4"	"hsa:5704; P43686; Q96FV5; Q9UBM3; Q9UEX3"	"Regulation of RAS by GAPs; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"64"	"0"	"11.8"	"12.2"	"11.2"	"10.8"	"13.1"	"14.6"	"16.9"	"1.6"	"89.3"	"100.9"	"281.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BZ8"	"Leukocyte receptor cluster member 1 OS=Homo sapiens OX=9606 GN=LENG1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"264"	"30.5"	"9.69"	"440.56"	"5.18"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"19.7"	"20.7"	"18.7"	"17.3"	"16.8"	"35.2"	"45.1"	"0.0"	"168.2"	"173.6"	"272.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92879"	"CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"486"	"52.0"	"8.46"	"229.43"	"5.18"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10658"	"ENSG00000149187"	"CELF1"	"B4E2U5; D3DQS0; F8W940; hsa:10658; Q4LE52; Q92879; Q9NP83; Q9NR06"	""	"Adipogenesis; mRNA processing"	"2"	"0"	"193.7"	"144.6"	"177.0"	"176.6"	"169.8"	"147.2"	"190.8"	"0.0"	"923.0"	"934.6"	"1857.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NQ48"	"Leucine zipper transcription factor-like protein 1 OS=Homo sapiens OX=9606 GN=LZTFL1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"299"	"34.6"	"5.36"	""	"5.18"	""	"1"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf15294"	"54585"	"ENSG00000163818"	"LZTFL1"	"B3KSI9; B4E0K7; hsa:54585; Q8TC61; Q9NQ48; Q9NQ56"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"5"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.6"	"2.4"	"7.1"	"1.6"	"153.8"	"146.1"	"354.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02241"	"Kinesin-like protein KIF23 OS=Homo sapiens OX=9606 GN=KIF23 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"960"	"110.0"	"8.51"	"646.39"	"5.17"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf16540"	"9493"	"ENSG00000137807"	"KIF23"	"B4E1K0; hsa:9493; Q02241; Q8WVP0"	"MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; Mitotic Telophase/Cytokinesis"	"Pleural mesothelioma"	"5"	"0"	"6.3"	"7.2"	"12.5"	"8.2"	"7.4"	"7.1"	"17.1"	"0.9"	"98.8"	"93.0"	"191.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13322"	"Growth factor receptor-bound protein 10 OS=Homo sapiens OX=9606 GN=GRB10 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"594"	"67.2"	"7.87"	"453.43"	"5.17"	"1"	"1"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00169, Pf00788, Pf08947"	"2887"	"ENSG00000106070"	"GRB10"	"A4D258; A7VJ95; A8K0E6; D3DVM9; hsa:2887; O00427; O00701; O75222; Q13322; Q92606; Q92907; Q92948"	"RET signaling; Signaling by SCF-KIT; FLT3 Signaling; Response of EIF2AK1 (HRI) to heme deficiency; IRS activation; Signal attenuation"	"Kit receptor signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; EGF/EGFR signaling pathway; Insulin signaling"	"13"	"0"	"9.0"	"7.3"	"11.0"	"9.9"	"9.2"	"5.9"	"18.5"	"0.0"	"186.8"	"169.3"	"409.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UFC0"	"Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"647"	"70.8"	"7.21"	"516.55"	"5.16"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"222229"	"ENSG00000161036"	"LRWD1"	"A8K4K2; B2R9G2; hsa:222229; Q8N0T9; Q8WV43; Q96GJ2; Q9UFC0"	""	"Male infertility"	"1"	"0"	"44.8"	"41.0"	"57.2"	"50.1"	"40.8"	"50.0"	"88.5"	"0.0"	"718.3"	"771.0"	"1442.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95817"	"BAG family molecular chaperone regulator 3 OS=Homo sapiens OX=9606 GN=BAG3 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"575"	"61.6"	"6.95"	"460.93"	"5.15"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf02179"	"9531"	"ENSG00000151929"	"BAG3"	"A8K5L8; hsa:9531; O95817; Q3B763; Q9NT20; Q9P120"	"Regulation of HSF1-mediated heat shock response"	"Cell interactions of the pancreatic cancer microenvironment"	"2"	"0"	"9.2"	"8.9"	"13.3"	"12.6"	"9.5"	"10.7"	"30.4"	"1.2"	"59.0"	"50.1"	"114.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07948"	"Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"512"	"58.5"	"7.11"	"557.25"	"5.13"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"4067"	"ENSG00000254087"	"LYN"	"A0AVQ5; hsa:4067; P07948"	"CD209 (DC-SIGN) signaling; FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling; Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCERI mediated NF-kB activation; CD22 mediated BCR regulation; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); GPVI-mediated activation cascade; Cyclin D associated events in G1; Growth hormone receptor signaling; Inactivation of CSF3 (G-CSF) signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Erythropoietin activates STAT5; Erythropoietin activates RAS; Platelet Adhesion to exposed collagen; Dectin-2 family"	"IL-5 signaling pathway; RANKL/RANK signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; GDNF signaling"	"45"	"0"	"2.8"	"2.4"	"3.5"	"6.6"	"2.0"	"2.6"	"3.5"	"0.5"	"63.1"	"64.5"	"180.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TEW0"	"Partitioning defective 3 homolog OS=Homo sapiens OX=9606 GN=PARD3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1356"	"151.3"	"7.68"	""	"5.12"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf12053"	"56288"	"ENSG00000148498"	"PARD3"	"F5H5T0; hsa:56288; Q5T2U1; Q5VUA2; Q5VUA3; Q5VWV0; Q5VWV1; Q5VWV3; Q5VWV4; Q5VWV5; Q6IQ47; Q8TCZ9; Q8TEW0; Q8TEW1; Q8TEW2; Q8TEW3; Q96K28; Q96RM6; Q96RM7; Q9BY57; Q9BY58; Q9HC48; Q9NWL4; Q9NYE6"	"Tight junction interactions; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)"	"Chemokine signaling pathway; Complement system in neuronal development and plasticity"	"4"	"0"	"15.9"	"10.4"	"13.4"	"9.1"	"11.4"	"10.5"	"20.3"	"2.0"	"133.1"	"118.3"	"241.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRT2"	"Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1"	"0.000"	""	"10"	"1"	"2"	"1"	"126"	"14.9"	"7.37"	"390.31"	"5.11"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	""	"Pf20180"	"84300"	"ENSG00000137288"	"UQCC2"	"B2R4I0; hsa:84300; Q9BRT2"	""	"Mitochondrial complex III assembly"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q69YH5"	"Cell division cycle-associated protein 2 OS=Homo sapiens OX=9606 GN=CDCA2 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1023"	"112.6"	"8.40"	""	"5.09"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15276"	"157313"	"ENSG00000184661"	"CDCA2"	"hsa:157313; Q3SX74; Q4G0W0; Q5RKN0; Q69YH5; Q69YI4; Q6P464; Q8N7C1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P45877"	"Peptidyl-prolyl cis-trans isomerase C OS=Homo sapiens OX=9606 GN=PPIC PE=1 SV=1"	""	""	"8"	"2"	"2"	"1"	"212"	"22.7"	"8.40"	""	"5.08"	""	"2"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00160"	"5480"	"ENSG00000168938"	"PPIC"	"A4LBB5; hsa:5480; P45877"	""	""	"0"	"0"	"15.8"	"6.3"	"16.9"	"17.4"	"13.1"	"11.1"	"17.2"	"0.0"	"153.2"	"151.5"	"329.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P61077"	"Ubiquitin-conjugating enzyme E2 D3 OS=Homo sapiens OX=9606 GN=UBE2D3 PE=1 SV=1"	""	""	"16"	"1"	"1"	"1"	"147"	"16.7"	"7.80"	""	"5.08"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00179"	"7323"	"ENSG00000109332"	"UBE2D3"	"A6NJ93; A6NJB1; A6NM99; hsa:7323; P47986; P61077; Q6IB88; Q6NXS4; Q8N924"	"Neddylation; Antigen processing: Ubiquitination & Proteasome degradation; E3 ubiquitin ligases ubiquitinate target proteins; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Peroxisomal protein import; IKK complex recruitment mediated by RIP1; Signaling by BMP; Inactivation of CSF3 (G-CSF) signaling; TICAM1, RIP1-mediated IKK complex recruitment; Regulation of TNFR1 signaling; Negative regulators of DDX58/IFIH1 signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity"	"Proteasome degradation"	"13"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86W56"	"Poly(ADP-ribose) glycohydrolase OS=Homo sapiens OX=9606 GN=PARG PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"976"	"111.0"	"6.43"	""	"5.08"	""	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05028"	"670; 8505"	"ENSG00000227345"	"PARG"	"A5YBK3; B2RC24; B4DIU5; B4DYR4; hsa:8505; I6RUV3; Q6E4P6; Q6E4P7; Q7Z742; Q86W56; Q9Y4W7"	"POLB-Dependent Long Patch Base Excision Repair"	"10q11.21q11.23 copy number variation syndrome"	"2"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.1"	"2.8"	"3.1"	"0.0"	"95.1"	"115.5"	"321.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62277"	"40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2"	"0.000"	""	"21"	"3"	"4"	"3"	"151"	"17.2"	"10.54"	"801.63"	"5.07"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00312, Pf08069"	"6207"	"ENSG00000110700"	"RPS13"	"B2R549; hsa:6207; P19116; P62277; Q02546; Q29200; Q498Y0"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"95.2"	"73.9"	"106.5"	"90.9"	"96.7"	"83.0"	"284.7"	"2.1"	"897.2"	"947.4"	"1652.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IY1"	"Kinetochore-associated protein NSL1 homolog OS=Homo sapiens OX=9606 GN=NSL1 PE=1 SV=3"	"0.000"	""	"9"	"2"	"4"	"2"	"281"	"32.1"	"6.79"	"711.29"	"5.07"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08641"	"25936"	"ENSG00000117697"	"NSL1"	"E7ETD5; hsa:25936; Q5SY75; Q96IY1; Q9H2M5; Q9NRN8; Q9Y415"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"15.8"	"14.5"	"21.6"	"13.4"	"13.7"	"19.7"	"36.0"	"3.0"	"667.6"	"652.2"	"2537.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95989"	"Diphosphoinositol polyphosphate phosphohydrolase 1 OS=Homo sapiens OX=9606 GN=NUDT3 PE=1 SV=1"	""	""	"10"	"2"	"2"	"1"	"172"	"19.5"	"6.34"	""	"5.07"	""	"2"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"11165"	"ENSG00000272325"	"NUDT3"	"B2R8N4; hsa:11165; O95989"	"Synthesis of pyrophosphates in the cytosol"	""	"1"	"0"	"24.0"	"13.9"	"29.6"	"31.1"	"35.2"	"45.1"	"120.2"	"2.9"	"493.2"	"423.2"	"694.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY89"	"Uncharacterized protein KIAA1671 OS=Homo sapiens OX=9606 GN=KIAA1671 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1806"	"196.6"	"8.47"	"529.87"	"5.06"	"1"	"1"	""	""	""	"Pf15327"	"85379"	"ENSG00000197077"	"KIAA1671"	"B0QYF2; B7ZW08; hsa:85379; Q5THZ5; Q9BY89"	""	""	"0"	"0"	"4.7"	"3.2"	"6.0"	"3.9"	"3.9"	"1.7"	"11.0"	"0.8"	"45.2"	"44.4"	"80.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPY8"	"Microtubule-associated protein RP/EB family member 3 OS=Homo sapiens OX=9606 GN=MAPRE3 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"281"	"32.0"	"5.54"	"456.87"	"5.05"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22924"	"ENSG00000084764"	"MAPRE3"	"B7WPK5; hsa:22924; O00265; Q6FHB0; Q6FI15; Q9BZP7; Q9BZP8; Q9UPY8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15013"	"Rho guanine nucleotide exchange factor 10 OS=Homo sapiens OX=9606 GN=ARHGEF10 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1369"	"151.5"	"5.68"	"476.96"	"5.05"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton"	"enzyme regulator activity;cytoskeletal activity"	"Pf00621, Pf19056, Pf19057"	"9639"	"ENSG00000104728; ENSG00000274726"	"ARHGEF10"	"hsa:9639; O14665; O15013; Q2KHR8; Q68D55; Q8IWD9; Q8IY77"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	""	"7"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.2"	"0.0"	"40.1"	"38.9"	"106.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQC8"	"Intraflagellar transport protein 46 homolog OS=Homo sapiens OX=9606 GN=IFT46 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"304"	"34.3"	"4.54"	"460.24"	"5.05"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	""	"Pf12317"	"56912"	"ENSG00000118096"	"IFT46"	"A8K0F6; hsa:56912; Q9H6V5; Q9NQC8"	"Intraflagellar transport"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR)"	"4"	"0"	"2.9"	"0.0"	"0.0"	"2.3"	"2.5"	"2.5"	"8.0"	"0.0"	"65.2"	"60.4"	"145.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJX3"	"Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4"	"0.000"	""	"4"	"2"	"3"	"2"	"599"	"66.8"	"5.64"	"412.25"	"5.05"	"1"	"2"	""	""	""	"Pf13432"	"51434"	""	"ANAPC7"	"A0A024RBJ3; hsa:51434"	""	""	"0"	"0"	"10.4"	"10.0"	"6.6"	"8.9"	"10.2"	"10.3"	"25.1"	"2.3"	"204.8"	"229.3"	"574.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51532"	"Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1647"	"184.5"	"7.88"	"426.24"	"5.04"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00439, Pf07529, Pf07533, Pf08880, Pf14619"	"6597"	"ENSG00000127616"	"SMARCA4"	"B1A8Z4; B1A8Z5; B1A8Z6; B1A8Z7; E9PBR8; hsa:6597; O95052; P51532; Q9HBD3"	"Formation of the beta-catenin:TCF transactivating complex; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Interleukin-7 signaling; RMTs methylate histone arginines; EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"Androgen receptor network in prostate cancer; Pre-implantation embryo; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; Tumor suppressor activity of SMARCB1; Rett syndrome causing genes; Thermogenesis; Kleefstra syndrome"	"13"	"0"	"19.5"	"14.2"	"21.2"	"15.4"	"14.5"	"17.5"	"48.6"	"0.0"	"184.1"	"187.5"	"364.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96JM7"	"Lethal(3)malignant brain tumor-like protein 3 OS=Homo sapiens OX=9606 GN=L3MBTL3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"780"	"88.3"	"6.46"	""	"5.04"	""	"1"	"cell organization and biogenesis;other biological processes"	"nucleus"	"other molecular function"	"Pf00536, Pf02820"	"84456"	"ENSG00000198945"	"L3MBTL3"	"hsa:84456; Q4VXE1; Q5VUM9; Q6P9B5; Q96JM7"	""	""	"0"	"0"	"18.9"	"26.8"	"15.0"	"18.5"	"17.2"	"11.7"	"61.8"	"0.0"	"278.5"	"317.0"	"479.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13823"	"Nucleolar GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GNL2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"731"	"83.6"	"9.25"	"647.02"	"5.04"	"2"	"2"	"other biological processes"	"nucleus"	"other molecular function"	"Pf01926, Pf08153"	"29889"	"ENSG00000134697"	"GNL2"	"hsa:29889; Q13823; Q9BWN7"	""	""	"0"	"0"	"140.8"	"100.4"	"122.1"	"123.1"	"118.0"	"112.6"	"201.7"	"1.7"	"480.0"	"472.6"	"898.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TE49"	"OTU domain-containing protein 7A OS=Homo sapiens OX=9606 GN=OTUD7A PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"926"	"100.6"	"8.40"	"537.67"	"5.03"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01754, Pf02338, Pf14555"	"161725"	"ENSG00000169918"	"OTUD7A"	"hsa:161725; Q8IWK5; Q8TE49"	"Ovarian tumor domain proteases"	"15q13.3 copy number variation syndrome; 15q11q13 copy number variation"	"3"	"0"	"0.0"	"0.0"	"2.6"	"0.0"	"2.0"	"1.8"	"3.8"	"2.7"	"55.3"	"49.1"	"113.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00116"	"Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"658"	"72.9"	"7.34"	"882.12"	"5.02"	"2"	"1"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01565, Pf02913"	"8540"	"ENSG00000018510"	"AGPS"	"A5D8U9; hsa:8540; O00116; Q2TU35"	"Plasmalogen biosynthesis; TYSND1 cleaves peroxisomal proteins"	"Triacylglyceride synthesis"	"4"	"0"	"8.2"	"9.9"	"12.0"	"10.0"	"9.4"	"9.3"	"21.8"	"0.0"	"138.0"	"120.7"	"255.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96TC7"	"Regulator of microtubule dynamics protein 3 OS=Homo sapiens OX=9606 GN=RMDN3 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"470"	"52.1"	"5.10"	"486.80"	"5.01"	"1"	"1"	"other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity"	""	"55177"	"ENSG00000137824"	"RMDN3"	"A9UMZ9; B3KRR3; hsa:55177; Q6ZWE9; Q96H23; Q96SD6; Q96TC7; Q9H6G1; Q9NVQ6"	""	""	"0"	"0"	"27.0"	"22.1"	"22.4"	"19.2"	"24.8"	"39.3"	"32.5"	"0.0"	"249.9"	"261.0"	"594.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00796"	"Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4"	"0.000"	""	"5"	"2"	"4"	"2"	"357"	"38.3"	"7.97"	"583.91"	"5.01"	"2"	"2"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf00107, Pf08240"	"6652"	"ENSG00000140263"	"SORD"	"B2R655; B7Z3A6; hsa:6652; J3JZZ5; Q00796; Q16682; Q9UMD6"	"Formation of xylulose-5-phosphate; Fructose biosynthesis"	"Disorders of fructose metabolism; Polyol pathway"	"4"	"0"	"48.9"	"64.0"	"97.0"	"62.7"	"56.0"	"73.2"	"168.7"	"0.0"	"412.4"	"380.8"	"827.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JXB2"	"Putative ubiquitin-conjugating enzyme E2 N-like OS=Homo sapiens OX=9606 GN=UBE2NL PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"153"	"17.4"	"5.92"	"729.62"	"5.01"	"1"	"1"	"protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00179"	"389898"	""	"UBE2NL"	"E9KL27; hsa:389898; Q5JXB2"	""	""	"0"	"0"	"6.6"	"5.1"	"11.4"	"8.6"	"9.8"	"8.1"	"15.6"	"0.0"	"269.4"	"417.2"	"1543.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPF8"	"Arf-GAP with dual PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ADAP2 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"2"	"381"	"44.3"	"9.36"	"773.74"	"5.01"	"3"	"2"	"developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"55803"	"ENSG00000184060"	"ADAP2"	"hsa:55803; Q8N4Q6; Q96SD5; Q9NPF8"	""	"TYROBP causal network in microglia"	"1"	"0"	"12.1"	"11.5"	"17.8"	"10.3"	"16.1"	"17.4"	"36.0"	"0.0"	"865.1"	"898.1"	"997.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IXM2"	"Chromatin complexes subunit BAP18 OS=Homo sapiens OX=9606 GN=BAP18 PE=1 SV=1"	""	""	"8"	"1"	"1"	"1"	"172"	"17.9"	"7.33"	""	"5.00"	""	"1"	"cell organization and biogenesis"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"124944"	"ENSG00000258315"	"BAP18"	"B4DIV3; C9J4G0; E9PB29; hsa:124944; Q8IXM2"	""	""	"0"	"0"	"25.3"	"18.5"	"21.0"	"20.3"	"14.9"	"27.9"	"35.2"	"0.0"	"137.8"	"154.6"	"406.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2S7"	"Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1"	""	""	"6"	"2"	"2"	"2"	"368"	"42.0"	"8.63"	""	"5.00"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04379, Pf08755"	"26073"	"ENSG00000004142"	"POLDIP2"	"B2R846; hsa:26073; Q96JE4; Q9Y2S7"	""	""	"0"	"0"	"46.1"	"38.8"	"47.7"	"56.1"	"41.9"	"37.7"	"68.5"	"0.6"	"195.0"	"206.9"	"609.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51398"	"28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"398"	"45.5"	"8.88"	"466.47"	"5.00"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10236"	"7818"	"ENSG00000132676"	"DAP3"	"B4DP59; B4DY62; E7EM60; hsa:7818; P51398; Q13044; Q68CT7; Q96Q20"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"CKAP4 signaling pathway map"	"4"	"0"	"8.4"	"9.8"	"10.0"	"4.6"	"8.6"	"10.9"	"22.7"	"1.0"	"79.5"	"87.1"	"135.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15504"	"Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1"	"0.000"	""	"3"	"1"	"3"	"1"	"423"	"44.8"	"9.19"	"240.05"	"5.00"	"1"	"1"	"transport"	"other membranes;cytosol;nucleus"	"other molecular function"	""	"11097"	"ENSG00000136243"	"NUP42"	"A4D143; B4DP42; hsa:11097; O15504; Q49AE7; Q9BS49"	"HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"28"	"0"	"27.1"	"21.9"	"30.9"	"30.7"	"32.5"	"27.5"	"56.5"	"2.9"	"249.1"	"264.2"	"481.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13371"	"Phosducin-like protein OS=Homo sapiens OX=9606 GN=PDCL PE=1 SV=3"	""	""	"6"	"1"	"4"	"1"	"301"	"34.3"	"4.73"	""	"4.99"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;other cell component"	""	"Pf02114"	"5082"	"ENSG00000136940"	"PDCL"	"hsa:5082; Q13371; Q4VXB6; Q96AF1; Q9UEW7; Q9UFL0; Q9UNX1; Q9UNX2"	"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding"	""	"1"	"0"	"2.8"	"0.0"	"0.0"	"6.2"	"2.7"	"0.0"	"2.3"	"0.0"	"501.3"	"433.5"	"1006.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3U8"	"60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3"	"0.000"	""	"15"	"2"	"4"	"2"	"105"	"12.2"	"11.59"	"617.41"	"4.99"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf01158"	"25873"	"ENSG00000130255"	"RPL36"	"B2R4Y1; D6W634; hsa:25873; Q6FIG1; Q9UQF6; Q9Y3U8"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"26.6"	"26.3"	"34.1"	"29.8"	"21.5"	"29.2"	"326.4"	"0.0"	"1018.9"	"1101.2"	"1609.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWA0"	"WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"830"	"94.4"	"5.96"	"268.89"	"4.98"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"84128"	"ENSG00000115368"	"WDR75"	"hsa:84128; Q8IWA0; Q96J10; Q9H8U8; Q9H9U5; Q9H9V8; Q9UIX2"	"rRNA modification in the nucleus and cytosol; Major pathway of rRNA processing in the nucleolus and cytosol"	""	"2"	"0"	"33.3"	"21.6"	"41.2"	"26.3"	"36.9"	"42.5"	"63.4"	"1.5"	"410.9"	"432.6"	"934.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXC6"	"COP9 signalosome complex subunit 9 OS=Homo sapiens OX=9606 GN=COPS9 PE=1 SV=3"	"0.000"	""	"35"	"1"	"2"	"1"	"57"	"6.2"	"3.83"	"457.73"	"4.98"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf15004"	"150678"	"ENSG00000172428"	"COPS9"	"hsa:150678; Q8N110; Q8WXC6"	""	"2q37 copy number variation syndrome"	"1"	"0"	"4.9"	"4.5"	"6.4"	"3.6"	"5.1"	"8.3"	"6.7"	"0.0"	"52.8"	"48.0"	"112.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53F19"	"Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2"	"0.000"	""	"4"	"2"	"6"	"2"	"620"	"70.5"	"5.73"	"1389.14"	"4.97"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf10309"	"55421"	"ENSG00000074356"	"NCBP3"	"B3KWG7; hsa:55421; Q53F19; Q7L406; Q96FK1; Q9NXZ4"	""	""	"0"	"0"	"126.2"	"108.2"	"112.2"	"109.2"	"89.8"	"102.1"	"231.8"	"2.5"	"490.9"	"535.5"	"969.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RT1"	"Erbin OS=Homo sapiens OX=9606 GN=ERBIN PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1412"	"158.2"	"5.50"	"593.58"	"4.96"	"2"	"2"	"cell adhesion;cell organization and biogenesis;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00595, Pf13855"	"55914"	"ENSG00000112851"	"ERBIN"	"A0AVR1; B4E3F1; B7ZLV9; E7EQW9; E9PCR8; hsa:55914; Q1RMD0; Q86W38; Q96RT1; Q9NR18; Q9NW48; Q9ULJ5"	"RHOA GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Downregulation of ERBB2 signaling; RHOC GTPase cycle; RHOB GTPase cycle; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"Nucleotide-binding oligomerization domain (NOD) pathway; Nod-like receptor (NLR) signaling pathway; Pathways affected in adenoid cystic carcinoma"	"26"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03001"	"Dystonin OS=Homo sapiens OX=9606 GN=DST PE=1 SV=4"	"0.000"	""	"0"	"1"	"2"	"1"	"7570"	"860.1"	"5.25"	"688.61"	"4.96"	"1"	"1"	"cell adhesion;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00681, Pf02187, Pf13499, Pf17902, Pf18373"	"667"	"ENSG00000151914"	"DST"	"B7Z3H1; E7ERU0; hsa:667; O94833; Q03001; Q12825; Q13266; Q13267; Q13775; Q5TBT0; Q5TBT2; Q5TF23; Q5TF24; Q8N1T8; Q8N8J3; Q8WXK8; Q8WXK9; Q96AK9; Q96DQ5; Q96J76; Q96QT5; Q9H555; Q9UGD7; Q9UGD8; Q9UN10"	"RND2 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Type I hemidesmosome assembly"	""	"6"	"0"	"3.3"	"0.0"	"0.0"	"3.0"	"0.0"	"4.9"	"8.5"	"0.0"	"94.1"	"106.4"	"242.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12923"	"Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2485"	"276.7"	"6.42"	"465.50"	"4.96"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00102, Pf00373, Pf00595, Pf09379, Pf09380, Pf16599"	"5783"	"ENSG00000163629"	"PTPN13"	"B2RTR0; hsa:5783; Q12923; Q15159; Q15263; Q15264; Q15265; Q15674; Q16826; Q8IWH7; Q9NYN9; Q9UDA8"	"RND2 GTPase cycle; Synthesis of PIPs at the plasma membrane; RND3 GTPase cycle; RND1 GTPase cycle; Interleukin-37 signaling"	"Apoptosis modulation and signaling; Ectoderm differentiation; Ectoderm differentiation"	"8"	"0"	"6.1"	"5.1"	"3.0"	"3.9"	"4.4"	"4.8"	"12.2"	"2.6"	"99.8"	"92.5"	"183.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEF9"	"Serum response factor-binding protein 1 OS=Homo sapiens OX=9606 GN=SRFBP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"429"	"48.6"	"9.58"	"379.39"	"4.96"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf09073"	"153443"	"ENSG00000151304"	"SRFBP1"	"hsa:153443; Q5QFI2; Q8NEF9; Q96AH4; Q96DK2"	""	""	"0"	"0"	"13.0"	"10.7"	"17.1"	"17.8"	"11.3"	"17.3"	"42.2"	"1.3"	"145.3"	"133.1"	"272.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60493"	"Sorting nexin-3 OS=Homo sapiens OX=9606 GN=SNX3 PE=1 SV=3"	"0.000"	""	"12"	"1"	"2"	"1"	"162"	"18.8"	"8.66"	"576.77"	"4.96"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00787"	"8724"	"ENSG00000112335"	"SNX3"	"A8K0B1; E1P5E4; E1P5E5; hsa:8724; O60493; O60718; Q4TT29; Q4TT31; Q5JXJ7; Q5JXJ8; Q96AP9; Q9C0J5; Q9NU45"	"Ub-specific processing proteases; WNT ligand biogenesis and trafficking"	""	"2"	"0"	"3.3"	"0.0"	"3.9"	"3.0"	"2.9"	"3.1"	"4.6"	"1.7"	"55.2"	"52.5"	"201.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SVZ6"	"Zinc finger MYM-type protein 1 OS=Homo sapiens OX=9606 GN=ZMYM1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"4"	"1"	"1142"	"128.6"	"7.44"	"549.81"	"4.94"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf05699, Pf06467, Pf14291"	"79830"	"ENSG00000197056"	"ZMYM1"	"D3DPR7; hsa:79830; Q5SVZ6; Q7Z3Q4"	""	""	"0"	"0"	"0.0"	"0.0"	"2.3"	"2.4"	"3.7"	"2.1"	"5.6"	"1.9"	"71.5"	"75.5"	"159.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBF4"	"Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=ZCRB1 PE=1 SV=2"	"0.000"	""	"12"	"2"	"5"	"2"	"217"	"24.6"	"8.53"	"816.36"	"4.94"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00098"	"85437"	"ENSG00000139168"	"ZCRB1"	"hsa:85437; Q6PJX0; Q8TBF4; Q96TA6"	"mRNA Splicing - Minor Pathway; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	""	"3"	"0"	"20.2"	"17.2"	"18.2"	"16.1"	"19.5"	"10.5"	"33.1"	"0.9"	"102.1"	"107.1"	"217.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXK1"	"Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"252"	"25.4"	"9.88"	"689.83"	"4.94"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"83855"	"ENSG00000129911"	"KLF16"	"hsa:83855; Q9BXK1"	""	""	"0"	"0"	"0.0"	"0.0"	"2.5"	"3.5"	"0.0"	"2.9"	"9.4"	"0.0"	"49.3"	"47.6"	"91.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NWY9"	"Pre-mRNA-processing factor 40 homolog B OS=Homo sapiens OX=9606 GN=PRPF40B PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"1"	"871"	"99.3"	"6.83"	"289.96"	"4.94"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00397, Pf01846"	"25766"	"ENSG00000110844"	"PRPF40B"	"hsa:25766; O75401; Q6NWY9; Q6PI09; Q6ZWB3; Q8NCZ1; Q9H5G4; Q9NT95"	""	""	"0"	"0"	"3.7"	"0.0"	"0.0"	"2.1"	"2.3"	"2.6"	"3.4"	"0.0"	"35.0"	"32.1"	"56.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8W3"	"Protein FAM204A OS=Homo sapiens OX=9606 GN=FAM204A PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"233"	"27.0"	"7.91"	"491.45"	"4.94"	"1"	"1"	""	""	""	""	"63877"	"ENSG00000165669"	"FAM204A"	"D3DRC6; hsa:63877; Q5T373; Q9H5V5; Q9H8W3"	""	""	"0"	"0"	"17.7"	"13.1"	"22.2"	"20.5"	"18.0"	"16.8"	"54.6"	"0.0"	"199.3"	"243.5"	"481.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6DD87"	"Zinc finger protein 787 OS=Homo sapiens OX=9606 GN=ZNF787 PE=1 SV=4"	""	""	"5"	"1"	"1"	"1"	"382"	"40.4"	"7.96"	""	"4.93"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf13912"	"126208"	"ENSG00000142409"	"ZNF787"	"A0A087WUD1; hsa:126208; O00455; Q6DD87"	""	""	"0"	"0"	"8.1"	"9.2"	"8.4"	"12.6"	"7.1"	"6.3"	"23.3"	"0.4"	"59.5"	"60.4"	"142.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56381"	"ATP synthase subunit epsilon, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1E PE=1 SV=2"	"0.000"	""	"29"	"2"	"4"	"2"	"51"	"5.8"	"9.92"	"549.28"	"4.93"	"2"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04627"	"514"	"ENSG00000124172"	"ATP5F1E"	"B2RDD0; E1P5H6; hsa:514; P56381; Q53XU6"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"5"	"0"	"72.6"	"39.9"	"85.6"	"66.1"	"52.5"	"75.6"	"324.8"	"0.0"	"915.6"	"881.8"	"1686.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43929"	"Origin recognition complex subunit 4 OS=Homo sapiens OX=9606 GN=ORC4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"436"	"50.3"	"8.00"	"440.13"	"4.90"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13191, Pf14629"	"5000"	"ENSG00000115947"	"ORC4"	"B7Z3D0; B7Z5F1; D3DP86; F5H069; hsa:5000; O43929; Q96C42"	"Orc1 removal from chromatin; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"10"	"0"	"6.7"	"8.3"	"14.0"	"9.7"	"10.2"	"7.9"	"42.3"	"0.0"	"196.7"	"196.7"	"329.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXW9"	"Fanconi anemia group D2 protein OS=Homo sapiens OX=9606 GN=FANCD2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1451"	"164.0"	"5.88"	"475.17"	"4.90"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14631"	"2177"	"ENSG00000144554"	"FANCD2"	"hsa:2177; Q2LA86; Q69YP9; Q6PJN7; Q9BQ06; Q9BXW9; Q9H9T9"	"TP53 Regulates Transcription of DNA Repair Genes; Fanconi Anemia Pathway"	"miRNA regulation of DNA damage response; 15q13.3 copy number variation syndrome; DNA repair pathways, full network; 15q11q13 copy number variation; DNA damage response"	"7"	"0"	"6.8"	"4.6"	"11.8"	"6.9"	"10.0"	"7.8"	"16.2"	"3.0"	"63.5"	"82.7"	"129.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14203"	"Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"1"	"1278"	"141.6"	"5.81"	"543.07"	"4.90"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf12455"	"1639"	"ENSG00000204843"	"DCTN1"	"A8MY36; B4DM45; E9PFS5; E9PGE1; G5E9H4; hsa:1639; O95296; Q14203; Q6IQ37; Q9BRM9; Q9UIU1; Q9UIU2"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Signaling by ALK fusions and activated point mutants; XBP1(S) activates chaperone genes"	""	"6"	"0"	"0.0"	"0.0"	"3.3"	"0.0"	"3.2"	"4.6"	"6.8"	"1.0"	"37.4"	"38.6"	"73.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZX2"	"Uridine-cytidine kinase 2 OS=Homo sapiens OX=9606 GN=UCK2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"261"	"29.3"	"6.70"	"493.66"	"4.89"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00485"	"7371"	"ENSG00000143179"	"UCK2"	"hsa:7371; Q5VV91; Q7KZV3; Q92528; Q96KG5; Q9BU42; Q9BZX2"	"Pyrimidine salvage"	"Fluoropyrimidine activity; Pyrimidine metabolism"	"3"	"0"	"5.1"	"0.0"	"3.3"	"5.5"	"4.2"	"5.3"	"8.4"	"0.0"	"75.0"	"76.1"	"201.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00423"	"Echinoderm microtubule-associated protein-like 1 OS=Homo sapiens OX=9606 GN=EML1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"815"	"89.8"	"7.06"	"664.51"	"4.89"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451"	"2009"	"ENSG00000066629"	"EML1"	"hsa:2009; O00423; Q86U15; Q8N536; Q8N5C4; Q8WWL6"	""	""	"0"	"0"	"27.8"	"14.7"	"26.8"	"27.5"	"24.7"	"24.4"	"53.6"	"0.0"	"374.7"	"355.8"	"680.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PJI9"	"GATOR complex protein WDR59 OS=Homo sapiens OX=9606 GN=WDR59 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"974"	"109.7"	"7.91"	"531.60"	"4.85"	"1"	"1"	"stress response;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400, Pf17120"	"79726"	"ENSG00000103091"	"WDR59"	"B3KRC3; hsa:79726; Q6PJI9; Q71RE7; Q96PW5; Q9BSW6; Q9HA43"	"Amino acids regulate mTORC1"	""	"1"	"0"	"3.6"	"6.2"	"5.8"	"5.8"	"5.9"	"6.7"	"6.9"	"0.5"	"57.9"	"75.2"	"141.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6E0"	"Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"443"	"49.3"	"5.69"	"433.82"	"4.85"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8428"	"ENSG00000102572"	"STK24"	"hsa:8428; O14840; Q5JV92; Q9Y6E0"	"Apoptotic cleavage of cellular proteins"	""	"2"	"0"	"0.0"	"0.0"	"3.9"	"0.0"	"0.0"	"3.7"	"5.7"	"0.0"	"60.5"	"59.0"	"229.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN3"	"Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4"	"0.000"	""	"0"	"3"	"4"	"3"	"7388"	"837.8"	"5.39"	"564.46"	"4.85"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00681, Pf02187, Pf13499, Pf17902, Pf18373"	"23499"	"ENSG00000127603"	"MACF1"	"B1ALC5; E9PJT0; hsa:23499; O75053; Q5VW20; Q8WXY1; Q8WXY2; Q96PK2; Q9H540; Q9UKP0; Q9ULG9; Q9UPN3"	""	"Mesodermal commitment pathway; Mesodermal commitment pathway"	"2"	"0"	"8.5"	"6.4"	"19.2"	"15.9"	"16.7"	"14.5"	"29.6"	"1.4"	"297.4"	"327.5"	"653.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UK59"	"Lariat debranching enzyme OS=Homo sapiens OX=9606 GN=DBR1 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"544"	"61.5"	"5.47"	""	"4.85"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00149, Pf05011"	"51163"	"ENSG00000138231"	"DBR1"	"hsa:51163; Q96GH0; Q9NXQ6; Q9UK59"	""	""	"0"	"0"	"0.0"	"0.0"	"6.7"	"3.8"	"2.4"	"0.0"	"7.8"	"0.0"	"46.0"	"55.5"	"86.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13889"	"General transcription factor IIH subunit 3 OS=Homo sapiens OX=9606 GN=GTF2H3 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"308"	"34.4"	"7.02"	"419.98"	"4.84"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf03850"	"2967"	"ENSG00000111358"	"GTF2H3"	"B2R819; B4DNZ6; hsa:2967; Q13889; Q7L0G0; Q96AT7"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	"4.5"	"6.2"	"8.6"	"4.7"	"8.3"	"7.9"	"30.3"	"0.0"	"464.4"	"410.8"	"643.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDP1"	"Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"164"	"17.8"	"5.03"	"354.30"	"4.84"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	""	"Pf08615"	"84153"	"ENSG00000172922"	"RNASEH2C"	"hsa:84153; Q8TDP1; Q9H7F5"	""	""	"0"	"0"	"13.2"	"11.2"	"16.0"	"13.9"	"15.9"	"17.1"	"19.8"	"0.0"	"298.1"	"250.7"	"561.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7B2"	"Ribosome production factor 2 homolog OS=Homo sapiens OX=9606 GN=RPF2 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"306"	"35.6"	"9.99"	"529.99"	"4.83"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"84154"	"ENSG00000197498"	"RPF2"	"hsa:84154; Q5VXN1; Q8N4A1; Q9H7B2"	""	""	"0"	"0"	"15.9"	"10.0"	"20.1"	"20.3"	"23.6"	"15.0"	"40.6"	"0.0"	"110.0"	"87.9"	"183.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5PRF9"	"Protein Smaug homolog 2 OS=Homo sapiens OX=9606 GN=SAMD4B PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"694"	"75.4"	"6.83"	"505.31"	"4.83"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536"	"55095"	"ENSG00000179134"	"SAMD4B"	"A5Z0M6; hsa:55095; Q5PRF9; Q6P194"	""	""	"0"	"0"	"2.6"	"0.0"	"2.4"	"2.6"	"3.6"	"3.0"	"4.1"	"1.3"	"52.2"	"64.2"	"140.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6R4"	"Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1146"	"127.5"	"7.64"	"455.50"	"4.82"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	""	"Pf03813, Pf17403, Pf17404, Pf17405, Pf17406, Pf17407"	"65083"	"ENSG00000165271"	"NOL6"	"hsa:65083; Q5T5M3; Q5T5M4; Q7L4G6; Q8N6I0; Q8TEY9; Q8TEZ0; Q8TEZ1; Q9H675; Q9H6R4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"17.7"	"22.8"	"23.1"	"19.9"	"14.6"	"19.0"	"42.8"	"0.0"	"222.9"	"199.7"	"449.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14893"	"Gem-associated protein 2 OS=Homo sapiens OX=9606 GN=GEMIN2 PE=1 SV=1"	""	""	"8"	"1"	"1"	"1"	"280"	"31.6"	"5.58"	""	"4.82"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04938"	"8487"	"ENSG00000092208"	"GEMIN2"	"B2R9W8; hsa:8487; O14893; Q2M3B3; Q9H4F5; Q9NS77; Q9NS78; Q9NS79"	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	""	"2"	"0"	"6.2"	"4.3"	"8.2"	"5.6"	"1.7"	"4.8"	"13.9"	"0.0"	"79.5"	"83.9"	"205.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYN8"	"28S ribosomal protein S26, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS26 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"205"	"24.2"	"10.39"	"467.90"	"4.82"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf14943"	"64949"	"ENSG00000125901"	"MRPS26"	"hsa:64949; Q96Q58; Q9BYN8"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"57.9"	"42.1"	"55.4"	"48.9"	"53.4"	"53.1"	"137.5"	"4.1"	"379.4"	"338.2"	"669.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15006"	"ER membrane protein complex subunit 2 OS=Homo sapiens OX=9606 GN=EMC2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"297"	"34.8"	"6.57"	"651.26"	"4.82"	"1"	"1"	"cell organization and biogenesis"	"other membranes;ER/Golgi;other cell component"	""	"Pf14559"	"9694"	"ENSG00000104412"	"EMC2"	"hsa:9694; Q15006; Q8WUE1"	""	""	"0"	"0"	"6.7"	"6.4"	"6.8"	"5.4"	"5.9"	"8.8"	"19.9"	"0.0"	"333.0"	"327.0"	"807.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75461"	"Transcription factor E2F6 OS=Homo sapiens OX=9606 GN=E2F6 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"281"	"31.8"	"5.50"	"475.19"	"4.81"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02319, Pf16421"	"1876"	"ENSG00000169016"	"E2F6"	"A8K2Z8; G5E936; hsa:1876; O60544; O75461; Q53QY9; Q6Q9Z6; Q7Z2H6"	"Transcriptional Regulation by E2F6; G1/S-Specific Transcription"	""	"2"	"0"	"10.5"	"4.3"	"12.0"	"13.1"	"10.8"	"12.2"	"14.4"	"3.1"	"87.8"	"89.1"	"208.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99959"	"Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2"	"0.000"	""	"3"	"3"	"4"	"2"	"881"	"97.4"	"9.33"	"547.27"	"4.80"	"2"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"5318"	"ENSG00000057294"	"PKP2"	"A0AV37; B8QFA1; B8QGS6; B8QGS7; D3DUW9; hsa:5318; Q4VC01; Q99959; Q99960"	"Formation of the cornified envelope"	"Arrhythmogenic right ventricular cardiomyopathy; Epithelial to mesenchymal transition in colorectal cancer"	"4"	"0"	"45.6"	"42.5"	"51.2"	"34.3"	"38.8"	"56.1"	"81.4"	"2.5"	"392.3"	"375.5"	"732.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UER7"	"Death domain-associated protein 6 OS=Homo sapiens OX=9606 GN=DAXX PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"740"	"81.3"	"4.87"	"473.64"	"4.79"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03344"	"1616"	"ENSG00000204209; ENSG00000206206; ENSG00000206279; ENSG00000227046; ENSG00000231617"	"DAXX"	"B4E1I3; F5ANJ6; F5ANJ7; F5H082; hsa:1616; O14747; O15141; O15208; Q5STK9; Q9BWI3; Q9UER7"	"HCMV Early Events; Inhibition of DNA recombination at telomere; SUMOylation of transcription cofactors; Regulation of TP53 Degradation; Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations; Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations"	"Androgen receptor signaling pathway; Amyotrophic lateral sclerosis (ALS); Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; p38 MAPK signaling pathway"	"11"	"0"	"24.6"	"18.5"	"22.8"	"21.7"	"20.7"	"22.9"	"46.5"	"0.0"	"414.9"	"441.7"	"1013.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29144"	"Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 SV=4"	"0.000"	""	"2"	"2"	"3"	"2"	"1249"	"138.3"	"6.32"	"269.88"	"4.79"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00082, Pf12580"	"7174"	"ENSG00000134900"	"TPP2"	"hsa:7174; P29144; Q5VZU8"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"3.7"	"0.0"	"4.2"	"6.4"	"0.7"	"68.1"	"66.1"	"195.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UI30"	"Multifunctional methyltransferase subunit TRM112-like protein OS=Homo sapiens OX=9606 GN=TRMT112 PE=1 SV=1"	""	""	"11"	"1"	"2"	"1"	"125"	"14.2"	"5.26"	""	"4.79"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03966"	"51504"	"ENSG00000173113"	"TRMT112"	"B2R539; hsa:51504; J3KNG5; Q3MHC7; Q8N2Z4; Q9UI30"	"Eukaryotic Translation Termination; Methylation; rRNA modification in the nucleus and cytosol; tRNA modification in the nucleus and cytosol"	""	"4"	"0"	"19.5"	"13.1"	"17.7"	"15.7"	"19.0"	"19.6"	"32.1"	"1.4"	"215.1"	"225.1"	"417.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60903"	"Protein S100-A10 OS=Homo sapiens OX=9606 GN=S100A10 PE=1 SV=2"	"0.000"	""	"18"	"1"	"2"	"1"	"97"	"11.2"	"7.37"	"665.09"	"4.79"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf01023"	"6281"	"ENSG00000197747"	"S100A10"	"A8K4V8; hsa:6281; P08206; P60903; Q5T1C5"	"Dissolution of Fibrin Clot"	"8p23.1 copy number variation syndrome; Prostaglandin synthesis and regulation"	"3"	"0"	"26.6"	"19.6"	"32.9"	"18.3"	"18.3"	"23.8"	"67.0"	"4.7"	"325.2"	"301.6"	"649.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A00"	"Protein phosphatase 1 regulatory subunit 14A OS=Homo sapiens OX=9606 GN=PPP1R14A PE=1 SV=1"	"0.000"	""	"16"	"2"	"3"	"2"	"147"	"16.7"	"9.38"	"779.81"	"4.78"	"2"	"1"	"other biological processes"	"cytosol"	"enzyme regulator activity"	"Pf05361"	"94274"	"ENSG00000167641"	"PPP1R14A"	"hsa:94274; Q7Z4X7; Q96A00; Q96S54"	"RHO GTPases activate PKNs"	"Hippo-Merlin signaling dysregulation; Airway smooth muscle cell contraction"	"3"	"0"	"17.0"	"15.3"	"20.2"	"17.5"	"18.8"	"22.3"	"60.4"	"6.2"	"1251.2"	"1198.9"	"2049.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63220"	"40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1"	"0.000"	""	"20"	"2"	"4"	"2"	"83"	"9.1"	"8.50"	"586.61"	"4.77"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01249"	"6227"	"ENSG00000171858"	"RPS21"	"hsa:6227; P35265; P63220"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"233.7"	"217.0"	"279.3"	"293.9"	"260.3"	"266.7"	"369.2"	"0.0"	"970.6"	"950.2"	"1656.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6UVY6"	"DBH-like monooxygenase protein 1 OS=Homo sapiens OX=9606 GN=MOXD1 PE=1 SV=1"	""	""	"4"	"2"	"2"	"2"	"613"	"69.6"	"6.43"	""	"4.75"	""	"2"	"other metabolic processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf01082, Pf03351, Pf03712"	"26002"	"ENSG00000079931"	"MOXD1"	"hsa:26002; Q5THU6; Q6UVY6; Q8NC97; Q8WV49; Q9H4M6; Q9Y4U3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H0W5"	"Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"538"	"59.3"	"8.63"	""	"4.75"	""	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf14893"	"83987"	"ENSG00000169515"	"CCDC8"	"hsa:83987; Q8TB26; Q9H0W5"	"Neddylation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NYI0"	"PH and SEC7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=PSD3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1048"	"116.0"	"5.99"	""	"4.75"	""	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf01369, Pf15410"	"23362"	"ENSG00000156011"	"PSD3"	"A6NFQ4; E9KL50; hsa:23362; Q6B003; Q9NYI0; Q9Y2F1"	""	""	"0"	"0"	"0.0"	"0.0"	"2.1"	"0.0"	"0.0"	"4.3"	"4.2"	"0.0"	"55.9"	"62.3"	"69.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WVM0"	"Dimethyladenosine transferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=TFB1M PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"346"	"39.5"	"9.26"	""	"4.74"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00398"	"51106"	"ENSG00000029639"	"TFB1M"	"hsa:51106; Q05DR0; Q8WVM0; Q9Y384"	"Transcriptional activation of mitochondrial biogenesis; rRNA modification in the mitochondrion"	"Energy metabolism; Mitochondrial gene expression"	"4"	"0"	"8.0"	"7.7"	"9.3"	"8.1"	"11.1"	"9.4"	"13.9"	"0.0"	"172.2"	"177.3"	"391.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N5A5"	"Zinc finger CCCH-type with G patch domain-containing protein OS=Homo sapiens OX=9606 GN=ZGPAT PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"531"	"57.3"	"5.43"	""	"4.71"	""	"1"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf18044"	"84619"	"ENSG00000197114"	"ZGPAT"	"E1P5K1; hsa:84619; Q4VXN9; Q5JWI9; Q5JWJ0; Q8N5A5; Q8NC55; Q8WUV4; Q96JI0; Q96JU4; Q9H401"	""	""	"0"	"0"	"33.7"	"23.1"	"32.8"	"37.5"	"32.9"	"14.0"	"36.0"	"0.0"	"214.9"	"216.7"	"493.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8H2"	"Probable ATP-dependent RNA helicase DDX31 OS=Homo sapiens OX=9606 GN=DDX31 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"851"	"94.0"	"9.99"	"550.83"	"4.71"	"1"	"1"	"other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"64794"	"ENSG00000125485"	"DDX31"	"hsa:64794; Q5K6N2; Q5K6N3; Q5K6N4; Q5VZJ4; Q5VZJ9; Q96E91; Q96NY2; Q96SX5; Q9H5K6; Q9H8H2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZI7"	"Upstream-binding protein 1 OS=Homo sapiens OX=9606 GN=UBP1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"540"	"60.5"	"6.35"	"276.57"	"4.71"	"1"	"2"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7342"	"ENSG00000153560"	"UBP1"	"hsa:7342; Q68CT0; Q86Y57; Q9H8V0; Q9NZI7; Q9UD76; Q9UD78"	""	""	"0"	"0"	"8.2"	"9.3"	"12.4"	"10.8"	"13.7"	"7.9"	"26.2"	"2.0"	"466.4"	"503.4"	"763.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92734"	"Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"400"	"43.4"	"5.10"	"457.76"	"4.71"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00564"	"10342"	"ENSG00000114354"	"TFG"	"D3DN49; G5E9V1; hsa:10342; K0J5S8; K0J6K2; Q15656; Q92734; Q969I2"	"Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1N0"	"Coiled-coil and C2 domain-containing protein 1A OS=Homo sapiens OX=9606 GN=CC2D1A PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"951"	"104.0"	"8.09"	"313.12"	"4.70"	"1"	"2"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00168"	"54862"	"ENSG00000132024; ENSG00000288293"	"CC2D1A"	"hsa:54862; Q6P1N0; Q7Z435; Q86XV0; Q8NF89; Q9H603; Q9NXI1"	""	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"1"	"0"	"65.0"	"44.5"	"81.3"	"63.8"	"72.9"	"62.8"	"145.6"	"0.5"	"534.4"	"495.2"	"992.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NRW7"	"Vacuolar protein sorting-associated protein 45 OS=Homo sapiens OX=9606 GN=VPS45 PE=1 SV=1"	""	""	"4"	"2"	"2"	"2"	"570"	"65.0"	"8.24"	""	"4.70"	""	"2"	"transport"	"other membranes;ER/Golgi;other cytoplasmic organelle"	""	"Pf00995"	"11311"	"ENSG00000136631"	"VPS45"	"D3DUZ9; F5H8K1; hsa:11311; Q15715; Q53FR8; Q5T4P6; Q9NRW7; Q9Y4Z6"	"Factors involved in megakaryocyte development and platelet production; Intra-Golgi traffic; SARS-CoV-2 modulates autophagy"	""	"3"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.9"	"2.7"	"7.1"	"0.8"	"60.4"	"66.0"	"182.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96FJ2"	"Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1"	""	""	"25"	"1"	"1"	"1"	"89"	"10.3"	"7.37"	""	"4.69"	""	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01221"	"140735"	"ENSG00000264364"	"DYNLL2"	"B2R5B4; hsa:140735; Q96FJ2"	"Separation of Sister Chromatids; MHC class II antigen presentation; Aggrephagy; HCMV Early Events; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPI-mediated anterograde transport; Intraflagellar transport; COPI-independent Golgi-to-ER retrograde traffic; Macroautophagy; Activation of BMF and translocation to mitochondria"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"18"	"0"	"15.8"	"12.7"	"19.3"	"16.8"	"17.0"	"11.7"	"20.1"	"1.5"	"64.0"	"54.2"	"103.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53597"	"Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4"	"0.000"	""	"4"	"1"	"2"	"1"	"346"	"36.2"	"8.79"	"473.96"	"4.69"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf02629"	"8802"	"ENSG00000163541"	"SUCLG1"	"hsa:8802; P53597; Q9BWB0; Q9UNP6"	"Citric acid cycle (TCA cycle)"	"Amino acid metabolism; TCA cycle (aka Krebs or citric acid cycle)"	"3"	"0"	"10.3"	"4.6"	"13.6"	"9.7"	"10.3"	"11.4"	"19.3"	"3.6"	"209.8"	"222.6"	"521.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUH3"	"RNA-binding protein 45 OS=Homo sapiens OX=9606 GN=RBM45 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"476"	"53.5"	"7.17"	"521.59"	"4.67"	"2"	"2"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"129831"	"ENSG00000155636"	"RBM45"	"hsa:129831; Q6NYL0; Q8IUH3; Q8NFC9"	""	""	"0"	"0"	"153.9"	"138.8"	"150.1"	"134.5"	"121.2"	"139.4"	"295.9"	"0.0"	"748.2"	"814.5"	"1274.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04760"	"Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4"	"0.000"	""	"11"	"1"	"2"	"1"	"184"	"20.8"	"5.31"	"487.31"	"4.67"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00903"	"2739"	"ENSG00000124767"	"GLO1"	"B2R6P7; B4DDV0; hsa:2739; P78375; Q04760; Q59EL0; Q5TZW3; Q96FC0; Q96J41"	"Pyruvate metabolism"	""	"1"	"0"	"20.4"	"27.7"	"37.2"	"37.3"	"20.1"	"24.0"	"36.0"	"0.0"	"108.6"	"117.9"	"192.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15008"	"26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"389"	"45.5"	"5.62"	"399.91"	"4.67"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf10602"	"9861"	"ENSG00000163636"	"PSMD6"	"A8K2E0; E9PHI9; hsa:9861; Q15008; Q6UV22"	"Separation of Sister Chromatids; Neutrophil degranulation; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"22.0"	"13.7"	"26.0"	"15.1"	"21.1"	"15.7"	"29.9"	"6.4"	"272.8"	"254.1"	"616.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRP0"	"Oligosaccharyltransferase complex subunit OSTC OS=Homo sapiens OX=9606 GN=OSTC PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"149"	"16.8"	"9.13"	"372.05"	"4.66"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf04756"	"58505"	"ENSG00000198856"	"OSTC"	"A8MYS2; B2R5H1; D6RH22; hsa:58505; Q9NRP0; Q9P075; Q9P1R4"	""	""	"0"	"0"	"12.2"	"10.5"	"13.9"	"11.0"	"17.9"	"11.7"	"29.5"	"5.3"	"309.3"	"347.8"	"583.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13206"	"Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"875"	"100.8"	"8.63"	"454.34"	"4.64"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"1662"	"ENSG00000178105"	"DDX10"	"B2RCQ3; hsa:1662; Q13206; Q5BJD8"	""	""	"0"	"0"	"14.4"	"13.6"	"24.4"	"14.1"	"13.1"	"21.1"	"56.8"	"0.0"	"175.2"	"201.3"	"411.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60568"	"Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 OS=Homo sapiens OX=9606 GN=PLOD3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"738"	"84.7"	"6.05"	"421.93"	"4.64"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"8985"	"ENSG00000106397"	"PLOD3"	"B2R6W6; hsa:8985; O60568; Q540C3"	"Collagen biosynthesis and modifying enzymes"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"3"	"0"	"6.1"	"3.0"	"8.6"	"9.3"	"9.2"	"8.0"	"13.1"	"3.3"	"47.7"	"58.9"	"95.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P158"	"Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"1"	"1386"	"155.5"	"7.71"	"643.85"	"4.63"	"2"	"2"	""	""	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf05773, Pf07717, Pf18044"	"90957"	"ENSG00000163214"	"DHX57"	"A2RRC7; hsa:90957; Q53SI4; Q6P158; Q6P9G1; Q7Z6H3; Q8NG17; Q96M33"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75145"	"Liprin-alpha-3 OS=Homo sapiens OX=9606 GN=PPFIA3 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"1"	"1194"	"133.4"	"5.68"	"680.37"	"4.62"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8541"	"ENSG00000177380"	"PPFIA3"	"A8K142; hsa:8541; O75145; Q3MJA0; Q9H8B5; Q9UEW4"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q658Y4"	"Protein FAM91A1 OS=Homo sapiens OX=9606 GN=FAM91A1 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"838"	"93.9"	"6.39"	""	"4.62"	""	"1"	"cell organization and biogenesis;transport"	"ER/Golgi;other cell component"	""	"Pf14647, Pf14648"	"157769"	"ENSG00000176853"	"FAM91A1"	"B6YY23; hsa:157769; Q658T5; Q658Y4; Q8TE89"	"RHOH GTPase cycle"	"Gastric cancer network 2"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQC6"	"Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"102"	"12.3"	"11.44"	"511.16"	"4.61"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf14978"	"78988"	"ENSG00000173141"	"MRPL57"	"A2A332; hsa:78988; Q9BQC6"	"Mitochondrial translation elongation; Mitochondrial translation initiation; Mitochondrial translation termination"	""	"3"	"0"	"25.6"	"24.5"	"26.4"	"18.2"	"26.4"	"32.6"	"69.9"	"1.3"	"223.9"	"212.1"	"438.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13797"	"Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"630"	"70.8"	"5.60"	"394.56"	"4.60"	"1"	"1"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf13499"	"5358"	"ENSG00000102024"	"PLS3"	"A8K579; B1AQ09; B4DGB4; B7Z6M1; hsa:5358; P13797; Q86YI6"	""	""	"0"	"0"	"12.9"	"9.1"	"28.1"	"15.6"	"14.6"	"8.7"	"26.0"	"0.0"	"132.1"	"128.9"	"382.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YN4"	"Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1812"	"201.9"	"5.01"	"557.18"	"4.59"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf15912"	"25962"	"ENSG00000164944"	"VIRMA"	"hsa:25962; Q2M1N0; Q69YN4; Q6AHX9; Q6NT78; Q7Z6C7; Q8IXH4; Q9BTH4; Q9H9C9; Q9NWR3; Q9P2B8; Q9UFW1"	""	""	"0"	"0"	"4.1"	"4.7"	"5.2"	"2.2"	"7.7"	"2.8"	"9.6"	"1.4"	"53.3"	"50.9"	"159.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4V328"	"GRIP1-associated protein 1 OS=Homo sapiens OX=9606 GN=GRIPAP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"841"	"95.9"	"5.11"	"395.94"	"4.59"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	""	"56850"	"ENSG00000068400"	"GRIPAP1"	"A6NL78; hsa:56850; Q3MJ75; Q4V327; Q4V328; Q4V330; Q5HYG1; Q6N046; Q96DH8; Q9NQ43; Q9ULQ3"	""	""	"0"	"0"	"11.2"	"8.6"	"11.5"	"6.2"	"12.5"	"6.1"	"26.3"	"4.8"	"306.1"	"289.3"	"507.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWV3"	"Reticulon-4-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=RTN4IP1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"396"	"43.6"	"9.11"	"470.85"	"4.58"	"1"	"1"	"developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf08240, Pf13602"	"84816"	"ENSG00000130347"	"RTN4IP1"	"hsa:84816; Q8N9B3; Q8WWV3; Q8WZ66; Q9BRA4"	""	""	"0"	"0"	"5.8"	"5.9"	"5.4"	"8.0"	"5.4"	"7.4"	"15.3"	"0.0"	"208.7"	"203.7"	"392.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVL6"	"Prolyl 3-hydroxylase 3 OS=Homo sapiens OX=9606 GN=P3H3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"736"	"81.8"	"6.32"	"425.53"	"4.58"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf13640"	"10536"	"ENSG00000110811"	"P3H3"	"hsa:10536; Q13512; Q15740; Q66K32; Q6NX61; Q7L2T1; Q8IVL6"	"Collagen biosynthesis and modifying enzymes"	""	"1"	"0"	"6.5"	"4.0"	"4.4"	"3.3"	"5.9"	"2.0"	"9.0"	"0.0"	"23.6"	"38.5"	"45.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62333"	"26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"389"	"44.1"	"7.49"	"525.01"	"4.58"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5706"	"ENSG00000100519"	"PSMC6"	"B2R975; hsa:5706; P49719; P62333; Q6IBU3; Q92524"	"Ub-specific processing proteases; Regulation of expression of SLITs and ROBOs; The role of GTSE1 in G2/M progression after G2 checkpoint; Separation of Sister Chromatids; RUNX1 regulates transcription of genes involved in differentiation of HSCs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-1 targets host intracellular signalling and regulatory pathways"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"34.2"	"16.6"	"38.2"	"28.5"	"36.0"	"28.7"	"48.7"	"0.6"	"200.8"	"203.6"	"406.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY7"	"Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"689"	"78.5"	"6.42"	"425.88"	"4.57"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;translational apparatus;nucleus"	"translation activity;nucleic acid binding activity"	"Pf13041, Pf13812"	"55037"	"ENSG00000132300"	"PTCD3"	"A6NHD2; D6W5M1; hsa:55037; Q597H0; Q658Y9; Q96EY7; Q9BUZ8; Q9NWL0"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"4.4"	"2.6"	"7.9"	"5.9"	"3.5"	"5.0"	"6.5"	"1.2"	"68.1"	"61.5"	"116.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2I1"	"Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1504"	"166.5"	"5.14"	"506.28"	"4.57"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787"	"11188"	"ENSG00000010322"	"NISCH"	"C9J245; hsa:11188; Q6PGP3; Q6PIB4; Q7L8M3; Q7Z2X6; Q9UES6; Q9UEU4; Q9UFW3; Q9Y2I1"	"RND3 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle"	""	"3"	"0"	"24.5"	"12.9"	"31.5"	"21.5"	"25.0"	"19.4"	"43.5"	"1.6"	"238.0"	"239.8"	"440.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L590"	"Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"875"	"98.1"	"8.75"	"229.87"	"4.57"	"1"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf09329, Pf09332"	"55388"	"ENSG00000065328"	"MCM10"	"A8K9I6; B7ZKZ8; hsa:55388; Q3MIR3; Q7L590; Q7LD55; Q96GX4; Q96NB6; Q9H0D7; Q9H3P9; Q9P177"	"Activation of ATR in response to replication stress; Activation of the pre-replicative complex"	"Ciliary landscape; DNA replication"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NRW3"	"DNA dC->dU-editing enzyme APOBEC-3C OS=Homo sapiens OX=9606 GN=APOBEC3C PE=1 SV=2"	""	""	"8"	"1"	"1"	"1"	"190"	"22.8"	"7.59"	""	"4.55"	""	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18782"	"27350"	"ENSG00000244509"	"APOBEC3C"	"B2R884; hsa:27350; Q5JZ92; Q7Z2N7; Q96F12; Q9NRW3"	"Formation of the Editosome"	""	"2"	"0"	"9.0"	"4.4"	"9.1"	"6.8"	"9.6"	"7.7"	"15.2"	"2.7"	"72.3"	"79.7"	"233.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNM6"	"26S proteasome non-ATPase regulatory subunit 13 OS=Homo sapiens OX=9606 GN=PSMD13 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"376"	"42.9"	"5.81"	"416.15"	"4.55"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"5719"	"ENSG00000185627"	"PSMD13"	"B3KT15; hsa:5719; O75831; Q53XU2; Q9UNM6; Q9UNV3"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"65"	"0"	"33.0"	"29.0"	"46.2"	"38.4"	"41.6"	"30.1"	"56.1"	"0.0"	"705.3"	"739.3"	"1859.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51553"	"Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3G PE=1 SV=1"	""	""	"6"	"2"	"2"	"2"	"393"	"42.8"	"8.50"	""	"4.53"	""	"2"	"other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf00180"	"3421"	"ENSG00000067829"	"IDH3G"	"E9PDD5; hsa:3421; P51553; Q9BUU5"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"TCA cycle (aka Krebs or citric acid cycle)"	"3"	"0"	"124.3"	"45.0"	"268.4"	"179.0"	"193.6"	"140.8"	"156.9"	"0.8"	"491.7"	"480.7"	"1138.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H098"	"Protein FAM107B OS=Homo sapiens OX=9606 GN=FAM107B PE=1 SV=1"	"0.000"	""	"18"	"2"	"3"	"2"	"131"	"15.5"	"8.29"	"856.51"	"4.52"	"2"	"1"	""	""	""	"Pf06625"	"83641"	"ENSG00000065809"	"FAM107B"	"A8K1P4; D3DRT2; hsa:83641; Q5T9K7; Q5T9K8; Q6ZSI4; Q9H098"	""	""	"0"	"0"	"23.7"	"21.3"	"23.5"	"24.6"	"22.7"	"24.1"	"41.8"	"0.0"	"199.3"	"211.7"	"358.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWJ5"	"Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1"	"0.000"	""	"17"	"1"	"2"	"1"	"86"	"10.1"	"6.35"	"407.34"	"4.51"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07189"	"83443"	"ENSG00000169976"	"SF3B5"	"B2R568; hsa:83443; Q7RTV1; Q9BWJ5"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"mRNA processing"	"3"	"0"	"38.9"	"26.3"	"33.5"	"35.2"	"31.9"	"18.8"	"105.0"	"0.0"	"284.0"	"256.7"	"569.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14497"	"AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2285"	"241.9"	"6.70"	"530.56"	"4.51"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf12031"	"8289"	"ENSG00000117713"	"ARID1A"	"D3DPL1; hsa:8289; O14497; Q53FK9; Q5T0W1; Q5T0W2; Q5T0W3; Q8NFD6; Q96T89; Q9BY33; Q9HBJ5; Q9UPZ1"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"Androgen receptor network in prostate cancer; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"7"	"0"	"0.0"	"3.6"	"4.3"	"5.6"	"4.0"	"1.6"	"4.2"	"0.0"	"34.5"	"32.6"	"60.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95619"	"YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"227"	"26.5"	"8.41"	"948.04"	"4.51"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03366"	"8089"	"ENSG00000127337"	"YEATS4"	"hsa:8089; O95619; Q9NQD0"	"HATs acetylate histones; Activation of the TFAP2 (AP-2) family of transcription factors"	""	"2"	"0"	"52.0"	"47.9"	"55.4"	"51.4"	"48.8"	"50.8"	"93.9"	"1.2"	"571.5"	"655.4"	"1042.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8MT69"	"Centromere protein X OS=Homo sapiens OX=9606 GN=CENPX PE=1 SV=1"	"0.000"	""	"17"	"1"	"2"	"1"	"81"	"9.0"	"5.90"	"488.39"	"4.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09415"	"201254"	"ENSG00000169689"	"CENPX"	"A8MT69; hsa:201254; O00281; O00282; Q96DD4; Q96F51"	"Fanconi Anemia Pathway; Deposition of new CENPA-containing nucleosomes at the centromere"	"DNA repair pathways, full network"	"3"	"0"	"0.0"	"0.0"	"2.2"	"0.0"	"0.0"	"0.0"	"1.6"	"0.0"	"111.8"	"107.6"	"261.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6N3"	"UPF0690 protein C1orf52 OS=Homo sapiens OX=9606 GN=C1orf52 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"182"	"20.6"	"5.21"	"328.51"	"4.49"	"1"	"1"	""	"nucleus"	""	"Pf15559"	"148423"	"ENSG00000162642"	"C1orf52"	"B3KX89; hsa:148423; Q8N6N3; Q8TDK5; Q8TDK6"	""	""	"0"	"0"	"46.9"	"38.9"	"49.2"	"45.9"	"51.0"	"51.1"	"61.3"	"0.0"	"196.3"	"202.3"	"343.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBQ5"	"Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"218"	"25.0"	"4.93"	"443.23"	"4.49"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10075"	"27335"	"ENSG00000178982; ENSG00000282986"	"EIF3K"	"A8K0I9; B7ZAM9; hsa:27335; Q96IQ0; Q9UBQ5; Q9Y6D1"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	""	"6"	"0"	"7.1"	"6.9"	"7.4"	"7.0"	"7.7"	"2.5"	"10.7"	"0.0"	"250.1"	"285.4"	"1012.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB5"	"Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"467"	"50.4"	"8.75"	"362.66"	"4.48"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"60682"	"ENSG00000112305"	"SMAP1"	"hsa:60682; Q53H70; Q5SYQ2; Q6PK24; Q8IYB5; Q8NDH4; Q96L38; Q96L39; Q9H8X4"	""	""	"0"	"0"	"28.1"	"27.8"	"23.6"	"27.2"	"23.3"	"17.2"	"44.6"	"1.6"	"276.1"	"253.9"	"411.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYB0"	"Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"399"	"44.2"	"4.73"	"341.95"	"4.47"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08914, Pf11626, Pf16589"	"54386"	"ENSG00000166848"	"TERF2IP"	"B4DQN4; hsa:54386; Q4W4Y2; Q8WYZ3; Q9NWR2; Q9NYB0"	"DNA Damage/Telomere Stress Induced Senescence; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; Meiotic synapsis; Telomere Extension By Telomerase; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; Packaging Of Telomere Ends; Removal of the Flap Intermediate from the C-strand"	"Splicing factor NOVA regulated synaptic proteins; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"16"	"0"	"33.5"	"21.8"	"33.0"	"33.9"	"23.9"	"35.3"	"58.6"	"0.0"	"152.1"	"144.1"	"268.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75449"	"Katanin p60 ATPase-containing subunit A1 OS=Homo sapiens OX=9606 GN=KATNA1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"491"	"55.9"	"6.90"	"473.18"	"4.46"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00004, Pf09336, Pf17862"	"11104"	"ENSG00000186625"	"KATNA1"	"E1P5A3; hsa:11104; O75449; Q5TFA8; Q5TFA9; Q86VN2; Q9NU52"	""	""	"0"	"0"	"10.1"	"12.0"	"17.2"	"14.4"	"18.7"	"15.4"	"40.0"	"3.0"	"275.6"	"266.5"	"598.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0JRZ9"	"F-BAR domain only protein 2 OS=Homo sapiens OX=9606 GN=FCHO2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"810"	"88.9"	"6.86"	"250.13"	"4.46"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00611, Pf10291"	"115548"	"ENSG00000157107"	"FCHO2"	"A8K6W7; B2RNQ9; B4DHK0; E9PG79; hsa:115548; Q0JRZ9; Q0JTJ3; Q96CF5"	"Cargo recognition for clathrin-mediated endocytosis"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15139"	"Serine/threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"912"	"101.6"	"6.62"	"479.78"	"4.46"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00169"	"5587"	"ENSG00000184304"	"PRKD1"	"A6NL64; B2RAF6; hsa:5587; Q15139"	"Sphingolipid de novo biosynthesis"	"Apoptosis modulation and signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Gastrin signaling pathway; Osteoblast differentiation and related diseases; Calcium regulation in cardiac cells"	"10"	"0"	"7.3"	"4.2"	"10.0"	"5.3"	"6.7"	"6.5"	"12.5"	"0.0"	"158.9"	"174.4"	"387.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKJ3"	"G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1502"	"164.1"	"8.66"	"407.42"	"4.46"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01585, Pf12171"	"23131"	"ENSG00000186566"	"GPATCH8"	"B9EGP9; hsa:23131; O60300; Q8TB99; Q9UKJ3"	""	""	"0"	"0"	"24.9"	"22.8"	"28.1"	"25.8"	"23.9"	"22.2"	"65.6"	"0.4"	"234.5"	"212.6"	"471.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP92"	"39S ribosomal protein S30, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS30 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"439"	"50.3"	"7.97"	"403.36"	"4.45"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf07147"	"10884"	"ENSG00000112996"	"MRPS30"	"hsa:10884; Q96I91; Q96Q19; Q9H0P8; Q9NP92; Q9NSF9; Q9NZ76"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TDD1"	"ATP-dependent RNA helicase DDX54 OS=Homo sapiens OX=9606 GN=DDX54 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"881"	"98.5"	"10.02"	""	"4.43"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"ER/Golgi;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00270, Pf00271, Pf08147"	"79039"	"ENSG00000123064"	"DDX54"	"hsa:79039; Q86YT8; Q8TDD1; Q9BRZ1"	""	""	"0"	"0"	"14.1"	"10.1"	"15.2"	"12.6"	"15.4"	"11.9"	"47.8"	"0.0"	"102.2"	"103.2"	"214.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSY1"	"BMP-2-inducible protein kinase OS=Homo sapiens OX=9606 GN=BMP2K PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1161"	"129.1"	"6.51"	"356.28"	"4.41"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf15282"	"55589"	"ENSG00000138756"	"BMP2K"	"hsa:55589; O94791; Q4W5H2; Q8IYF2; Q8N2G7; Q8NHG9; Q9NSY1; Q9NTG8"	""	""	"0"	"0"	"20.9"	"13.4"	"17.9"	"29.7"	"27.6"	"23.8"	"28.5"	"4.2"	"130.5"	"119.7"	"199.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2E3"	"Aprataxin OS=Homo sapiens OX=9606 GN=APTX PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"356"	"40.7"	"9.17"	"427.63"	"4.40"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11969, Pf16278, Pf17913"	"54840"	"ENSG00000137074"	"APTX"	"A8MTN4; D3DRK9; D3DRL0; hsa:54840; Q0P662; Q5T781; Q5T782; Q5T784; Q6JV81; Q6JV82; Q6JV85; Q7Z2E3; Q7Z2F3; Q7Z336; Q7Z5R5; Q7Z6V7; Q7Z6V8; Q9NXM5"	""	""	"0"	"0"	"13.3"	"12.1"	"15.2"	"16.8"	"15.9"	"15.0"	"19.1"	"0.0"	"251.6"	"246.1"	"534.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H446"	"RWD domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RWDD1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"243"	"27.9"	"4.20"	"473.23"	"4.40"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	""	"Pf05773"	"51389"	"ENSG00000111832"	"RWDD1"	"A8K3W2; A8MT24; hsa:51389; Q9H446; Q9Y313; Q9Y6B3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15484"	"Calpain-5 OS=Homo sapiens OX=9606 GN=CAPN5 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"640"	"73.1"	"7.64"	"368.99"	"4.40"	"1"	"1"	"protein metabolism;signal transduction"	"other cell component"	"other molecular function"	"Pf00168, Pf00648, Pf01067"	"726"	"ENSG00000149260"	"CAPN5"	"hsa:726; O00263; O15484"	"Degradation of the extracellular matrix"	"Integrin-mediated cell adhesion"	"2"	"0"	"4.1"	"5.5"	"5.7"	"8.1"	"3.0"	"4.9"	"8.1"	"0.0"	"45.9"	"57.8"	"83.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H1A4"	"Anaphase-promoting complex subunit 1 OS=Homo sapiens OX=9606 GN=ANAPC1 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"1944"	"216.4"	"6.30"	"762.13"	"4.39"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf12859, Pf18122, Pf19521, Pf20518"	"64682"	"ENSG00000153107"	"ANAPC1"	"hsa:64682; Q2M3H8; Q9BSE6; Q9H1A4; Q9H8D0"	"Senescence-Associated Secretory Phenotype (SASP); Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"Cell cycle; 2q13 copy number variation syndrome"	"20"	"0"	"15.2"	"10.0"	"19.5"	"10.4"	"17.0"	"12.5"	"21.5"	"1.1"	"196.8"	"170.0"	"538.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36915"	"Guanine nucleotide-binding protein-like 1 OS=Homo sapiens OX=9606 GN=GNL1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"607"	"68.6"	"5.80"	"434.79"	"4.39"	"1"	"1"	"stress response;signal transduction;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf01926"	"2794"	"ENSG00000204590; ENSG00000206492; ENSG00000226882; ENSG00000228581; ENSG00000229470; ENSG00000232143; ENSG00000235986"	"GNL1"	"B0S838; hsa:2794; P36915; Q96CT5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15437"	"Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2"	"0.000"	""	"2"	"1"	"3"	"1"	"767"	"86.4"	"6.89"	"885.42"	"4.37"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10483"	"ENSG00000101310"	"SEC23B"	"D3DW33; hsa:10483; Q15437; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7"	""	"Sterol regulatory element-binding proteins (SREBP) signaling"	"1"	"0"	"3.0"	"3.9"	"4.9"	"6.3"	"7.4"	"1.7"	"9.0"	"0.0"	"79.9"	"62.5"	"149.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75489"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"264"	"30.2"	"7.50"	"1050.46"	"4.36"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00329"	"4722"	"ENSG00000213619; ENSG00000285387"	"NDUFS3"	"B2R9J1; B4DFM8; hsa:4722; O75489; Q9UNQ8"	"RHOG GTPase cycle; Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"6"	"0"	"22.8"	"14.2"	"22.0"	"16.4"	"20.8"	"26.7"	"39.4"	"0.0"	"650.9"	"671.5"	"1330.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C037"	"E3 ubiquitin-protein ligase TRIM4 OS=Homo sapiens OX=9606 GN=TRIM4 PE=1 SV=2"	"0.000"	""	"2"	"1"	"8"	"1"	"500"	"57.4"	"8.10"	"477.52"	"4.36"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00622, Pf00643, Pf15227"	"89122"	"ENSG00000146833"	"TRIM4"	"A4D298; hsa:89122; Q75MK1; Q96F06; Q9C036; Q9C037"	"Antigen processing: Ubiquitination & Proteasome degradation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	""	"9"	"0"	"19.4"	"19.0"	"14.9"	"11.8"	"13.4"	"20.6"	"100.5"	"32.8"	"1412.2"	"1509.0"	"2859.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZR7"	"ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"859"	"96.3"	"9.06"	"509.52"	"4.36"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"57062"	"ENSG00000089737; ENSG00000273761"	"DDX24"	"E7EMJ4; hsa:57062; Q4V9L5; Q9GZR7"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"8.0"	"1.1"	"46.5"	"41.3"	"91.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y312"	"Protein AAR2 homolog OS=Homo sapiens OX=9606 GN=AAR2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"384"	"43.4"	"5.96"	"391.73"	"4.36"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf05282"	"25980"	"ENSG00000131043"	"AAR2"	"E1P5S7; hsa:25980; Q9H4F9; Q9P1P3; Q9UFK9; Q9Y312"	""	"Ciliary landscape"	"1"	"0"	"12.4"	"10.6"	"15.9"	"11.3"	"18.2"	"10.4"	"23.2"	"2.1"	"186.6"	"197.8"	"484.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15392"	"Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3"	"0.000"	""	"9"	"2"	"3"	"2"	"142"	"16.4"	"5.90"	"956.49"	"4.36"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00653"	"332"	"ENSG00000089685"	"BIRC5"	"A2SUH6; B2R4R1; hsa:332; O15392; Q2I3N8; Q4VGX0; Q53F61; Q5MGC6; Q6FHL2; Q75SP2; Q9P2W8"	"Separation of Sister Chromatids; Neddylation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Interleukin-4 and Interleukin-13 signaling; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"	"Apoptosis modulation and signaling; Interleukin-11 signaling pathway; Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Photodynamic therapy-induced NF-kB survival signaling; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; IL-4 signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Extracellular vesicles in the crosstalk of cardiac cells; Gastrin signaling pathway; Hepatitis B infection"	"24"	"0"	"39.5"	"23.3"	"39.0"	"38.6"	"40.4"	"33.6"	"91.4"	"3.0"	"516.0"	"474.3"	"958.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53985"	"Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"500"	"53.9"	"8.66"	"414.08"	"4.35"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf07690"	"6566"	"ENSG00000155380; ENSG00000281917"	"SLC16A1"	"hsa:6566; P53985; Q49A45; Q5T8R6; Q9NSJ9"	"Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"Photodynamic therapy-induced HIF-1 survival signaling; Fragile X syndrome; Glucose metabolism in triple-negative breast cancer cells"	"8"	"0"	"10.8"	"9.3"	"12.0"	"14.0"	"12.2"	"14.3"	"23.6"	"1.9"	"98.3"	"95.6"	"155.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y692"	"Glucocorticoid modulatory element-binding protein 1 OS=Homo sapiens OX=9606 GN=GMEB1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"4"	"1"	"573"	"62.6"	"4.83"	"507.54"	"4.35"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01342"	"10691"	"ENSG00000162419"	"GMEB1"	"B1AT48; hsa:10691; Q9NWH1; Q9UKD0; Q9Y692"	""	"2q37 copy number variation syndrome"	"1"	"0"	"23.9"	"15.1"	"21.2"	"18.4"	"21.6"	"12.4"	"17.9"	"0.0"	"439.2"	"470.1"	"880.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UB99"	"Ankyrin repeat domain-containing protein 11 OS=Homo sapiens OX=9606 GN=ANKRD11 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2663"	"297.7"	"7.11"	"551.10"	"4.34"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf12796"	"29123"	"ENSG00000167522"	"ANKRD11"	"hsa:29123; Q6NTG1; Q6QMF8; Q6UB99"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BV81"	"ER membrane protein complex subunit 6 OS=Homo sapiens OX=9606 GN=EMC6 PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"110"	"12.0"	"10.07"	"550.14"	"4.34"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf07019"	"83460"	"ENSG00000127774"	"EMC6"	"hsa:83460; Q9BV81"	""	""	"0"	"0"	"0.0"	"3.7"	"3.3"	"3.4"	"0.0"	"4.3"	"7.9"	"1.0"	"47.0"	"48.7"	"107.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0W8"	"Protein SMG9 OS=Homo sapiens OX=9606 GN=SMG9 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"520"	"57.6"	"7.01"	"582.93"	"4.34"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf10220"	"56006"	"ENSG00000105771"	"SMG9"	"hsa:56006; O60429; Q9H0W8; Q9H9A9"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"1"	"0"	"13.7"	"8.5"	"7.2"	"7.8"	"8.8"	"9.0"	"19.3"	"0.0"	"62.7"	"57.4"	"95.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43824"	"Putative GTP-binding protein 6 OS=Homo sapiens OX=9606 GN=GTPBP6 PE=2 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"516"	"56.9"	"9.42"	"445.30"	"4.33"	"1"	"1"	""	"other cell component"	"translation activity;other molecular function"	"Pf01926, Pf13167, Pf16360"	"8225"	"ENSG00000178605"	"GTPBP6"	"H0Y2S1; hsa:8225; O43824; Q53F77; Q5HYX8"	""	""	"0"	"0"	"0.0"	"2.8"	"2.4"	"3.7"	"3.3"	"4.7"	"3.5"	"0.0"	"48.1"	"40.3"	"74.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50750"	"Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"1"	"372"	"42.8"	"8.79"	"253.08"	"4.32"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"1025"	"ENSG00000136807"	"CDK9"	"hsa:1025; P50750; Q5JU24; Q5JU25; Q5U006; Q96TF1"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Interactions of Tat with host cellular proteins"	"MicroRNAs in cardiomyocyte hypertrophy; IL-9 signaling pathway; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; Male infertility"	"20"	"0"	"103.5"	"101.1"	"107.9"	"113.6"	"124.5"	"102.3"	"108.5"	"0.0"	"551.4"	"612.8"	"1070.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6G9"	"Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"523"	"56.5"	"6.42"	"389.82"	"4.31"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf05783"	"51143"	"ENSG00000144635"	"DYNC1LI1"	"A2RRG7; hsa:51143; Q53HC8; Q53HK7; Q9Y6G9"	"Separation of Sister Chromatids; MHC class II antigen presentation; Neutrophil degranulation; HCMV Early Events; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"15"	"0"	"46.6"	"45.4"	"47.8"	"48.2"	"33.0"	"48.7"	"75.0"	"0.5"	"263.8"	"258.5"	"432.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSH3"	"WD repeat-containing protein 44 OS=Homo sapiens OX=9606 GN=WDR44 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"913"	"101.3"	"5.45"	"398.65"	"4.31"	"1"	"1"	""	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"54521"	"ENSG00000131725"	"WDR44"	"B4DSE9; F8W913; hsa:54521; Q0JS52; Q0JTF3; Q5JSH2; Q5JSH3; Q6ZSC1; Q7Z365; Q7Z3P6; Q8NAU8; Q8NHU5; Q9NUV4"	""	"Ectoderm differentiation"	"1"	"0"	"13.3"	"11.8"	"18.4"	"12.5"	"25.8"	"33.7"	"67.5"	"5.3"	"476.6"	"396.7"	"873.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4J0"	"Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"409"	"47.2"	"6.32"	"477.91"	"4.31"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf07942"	"138199"	"ENSG00000156017"	"CARNMT1"	"hsa:138199; Q7Z383; Q8N4J0; Q8N7C5"	"Histidine catabolism"	""	"1"	"0"	"3.0"	"0.0"	"4.3"	"5.9"	"1.7"	"7.7"	"12.3"	"3.3"	"194.7"	"201.6"	"392.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43837"	"Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3B PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"385"	"42.2"	"8.46"	""	"4.30"	""	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00180"	"3420"	"ENSG00000101365"	"IDH3B"	"B2RDR1; D3DVX2; D3DVX3; hsa:3420; O43837; O95106; Q5JXS8; Q9NQ06; Q9NQ07; Q9NUZ0; Q9UEX0; Q9UG99"	"Citric acid cycle (TCA cycle)"	"TCA cycle (aka Krebs or citric acid cycle)"	"2"	"0"	"4.7"	"3.6"	"6.2"	"6.7"	"4.9"	"6.4"	"14.7"	"0.0"	"97.8"	"106.2"	"265.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02978"	"Mitochondrial 2-oxoglutarate/malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"314"	"34.0"	"9.91"	"433.01"	"4.29"	"1"	"1"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"8402"	"ENSG00000108528"	"SLC25A11"	"F5GY65; hsa:8402; O75537; Q02978; Q969P7"	"Gluconeogenesis"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"0.0"	"0.0"	"3.4"	"0.0"	"1.7"	"2.1"	"7.1"	"0.0"	"93.4"	"106.8"	"242.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N8A6"	"ATP-dependent RNA helicase DDX51 OS=Homo sapiens OX=9606 GN=DDX51 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"666"	"72.4"	"8.16"	"553.48"	"4.29"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"317781"	"ENSG00000185163; ENSG00000288503"	"DDX51"	"A8MPT9; hsa:317781; Q5CZ71; Q8IXK5; Q8N8A6; Q96ED1"	""	""	"0"	"0"	"4.8"	"0.0"	"0.0"	"4.3"	"2.5"	"4.2"	"12.3"	"0.0"	"28.9"	"28.3"	"55.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q3YEC7"	"Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"729"	"79.5"	"5.22"	""	"4.27"	""	"1"	""	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00071"	"55684"	"ENSG00000196642"	"RABL6"	"A8QVZ7; A8QVZ8; C6K8I4; C6K8I5; hsa:55684; Q3YEC7; Q4F968; Q5T5R7; Q8IWK1; Q8TCL4; Q8WU94; Q96SR8; Q9BU21; Q9H935"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"3.5"	"4.5"	"1.7"	"69.9"	"84.2"	"198.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0CG13"	"Chromosome transmission fidelity protein 8 homolog OS=Homo sapiens OX=9606 GN=CHTF8 PE=1 SV=1"	"0.000"	""	"15"	"1"	"2"	"1"	"121"	"13.3"	"8.18"	"382.15"	"4.27"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf09696"	"54921"	"ENSG00000168802"	"CHTF8"	"A8MYX8; hsa:54921; P0CG13; Q71E72; Q8NDH8; Q8WV66; Q9NX73"	"Polymerase switching on the C-strand of the telomere"	"Gastric cancer network 2"	"2"	"0"	"9.5"	"7.4"	"7.5"	"7.5"	"10.9"	"7.5"	"18.2"	"3.2"	"91.1"	"67.9"	"191.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H267"	"Vacuolar protein sorting-associated protein 33B OS=Homo sapiens OX=9606 GN=VPS33B PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"617"	"70.5"	"6.71"	""	"4.27"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00995"	"26276"	"ENSG00000184056"	"VPS33B"	"B3KQF6; hsa:26276; Q96K14; Q9H267; Q9NRP6; Q9NSF3"	"Prevention of phagosomal-lysosomal fusion; SARS-CoV-2 modulates autophagy"	""	"2"	"0"	"10.1"	"8.8"	"10.0"	"14.2"	"9.2"	"24.8"	"18.6"	"0.0"	"232.9"	"231.5"	"549.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99700"	"Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1313"	"140.2"	"9.57"	"367.76"	"4.26"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"6311"	"ENSG00000204842"	"ATXN2"	"A6NLD4; hsa:6311; Q24JQ7; Q6ZQZ7; Q99493; Q99700"	""	"Parkinson's disease pathway; EGF/EGFR signaling pathway"	"2"	"0"	"15.8"	"10.8"	"26.0"	"28.8"	"24.5"	"17.5"	"55.0"	"3.8"	"133.1"	"115.0"	"248.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10155"	"60 kDa SS-A/Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"538"	"60.6"	"8.03"	"386.03"	"4.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05731"	"6738"	"ENSG00000116747"	"RO60"	"B2RBB9; hsa:6738; P10155; Q5LJ98; Q5LJ99; Q5LJA0; Q86WL3; Q86WL4; Q92787; Q9H1W6"	""	""	"0"	"0"	"2.4"	"0.0"	"3.5"	"4.3"	"5.2"	"3.3"	"17.8"	"0.0"	"149.3"	"154.5"	"318.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRG1"	"Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1"	"0.000"	""	"16"	"2"	"3"	"2"	"176"	"20.7"	"6.34"	"1039.08"	"4.25"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05871"	"84313"	"ENSG00000131475"	"VPS25"	"B2R581; hsa:84313; Q9BRG1"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	""	"2"	"0"	"12.5"	"9.1"	"15.9"	"16.6"	"22.6"	"38.2"	"78.7"	"2.3"	"323.6"	"333.4"	"763.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93034"	"Cullin-5 OS=Homo sapiens OX=9606 GN=CUL5 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"780"	"90.9"	"7.94"	"369.78"	"4.25"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;signal transduction"	"cytosol;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00888, Pf10557"	"8065"	"ENSG00000166266"	"CUL5"	"A8K960; hsa:8065; O14766; Q93034; Q9BZC6"	"Neddylation; Antigen processing: Ubiquitination & Proteasome degradation; Inactivation of CSF3 (G-CSF) signaling; Vif-mediated degradation of APOBEC3G; Downregulation of ERBB2 signaling"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Dual hijack model of Vif in HIV infection; Modulators of TCR signaling and T cell activation; 10q11.21q11.23 copy number variation syndrome"	"9"	"0"	"0.0"	"0.0"	"3.1"	"3.2"	"0.0"	"0.0"	"6.8"	"0.9"	"101.0"	"111.3"	"206.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GX1"	"Tectonic-2 OS=Homo sapiens OX=9606 GN=TCTN2 PE=2 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"697"	"76.8"	"5.24"	"374.37"	"4.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	""	"Pf07773"	"79867"	"ENSG00000168778"	"TCTN2"	"A8K7Y8; B3KPW5; hsa:79867; Q96GX1; Q9H966"	"Anchoring of the basal body to the plasma membrane"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies"	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.6"	"0.0"	"107.2"	"121.5"	"190.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40763"	"Signal transducer and activator of transcription 3 OS=Homo sapiens OX=9606 GN=STAT3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"770"	"88.0"	"6.30"	"450.69"	"4.24"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00017, Pf01017, Pf02864, Pf02865"	"6774"	"ENSG00000168610"	"STAT3"	"A8K7B8; hsa:6774; K7ENL3; O14916; P40763; Q9BW54"	"Interleukin-4 and Interleukin-13 signaling; Senescence-Associated Secretory Phenotype (SASP); Interleukin-7 signaling; Signaling by SCF-KIT; Downstream signal transduction; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Cytoprotection by HMOX1; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-10 signaling; Growth hormone receptor signaling; Interleukin-6 signaling; Signaling by Leptin; PTK6 Activates STAT3; Inactivation of CSF3 (G-CSF) signaling; Signaling by cytosolic FGFR1 fusion mutants; Signaling by CSF1 (M-CSF) in myeloid cells; STAT3 nuclear events downstream of ALK signaling; BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members; POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation; Interleukin-20 family signaling; Interleukin-35 Signalling; Interleukin-23 signaling; Interleukin-27 signaling; Transcriptional regulation of granulopoiesis; Interleukin-37 signaling; Signalling to STAT3; Nuclear events stimulated by ALK signaling in cancer; MET activates STAT3; Interleukin-15 signaling; Interleukin-9 signaling; Interleukin-21 signaling"	"IL-5 signaling pathway; Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Cell differentiation - expanded index; Cell differentiation - index; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; IL-7 signaling pathway; IL-17 signaling pathway; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Androgen receptor network in prostate cancer; AGE/RAGE pathway; Interleukin-11 signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Mammary gland development pathway - Involution (Stage 4 of 4); Dopaminergic neurogenesis; IL-3 signaling pathway; TCA cycle nutrient use and invasiveness of ovarian cancer; Estrogen receptor pathway; Nuclear receptors meta-pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Development of pulmonary dendritic cells and macrophage subsets; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Leptin-insulin signaling overlap; IL-4 signaling pathway; Prion disease pathway; Clear cell renal cell carcinoma pathways; Non-small cell lung cancer; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Extracellular vesicles in the crosstalk of cardiac cells; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; EGF/EGFR signaling pathway; IL-10 anti-inflammatory signaling pathway ; Regulatory circuits of the STAT3 signaling pathway; Interactions between immune cells and microRNAs in tumor microenvironment; Neural crest cell migration during development; Neural crest cell migration in cancer; Cancer immunotherapy by PD-1 blockade; Measles virus infection; Gastrin signaling pathway; Hepatitis B infection; EGFR tyrosine kinase inhibitor resistance; TGF-beta receptor signaling in skeletal dysplasias; mBDNF and proBDNF regulation of GABA neurotransmission; IL-2 signaling pathway; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Th17 cell differentiation pathway; Urotensin-II-mediated signaling pathway; Inflammatory bowel disease signaling; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; Neurogenesis regulation in the olfactory epithelium; Autophagy in pancreatic ductal adenocarcinoma; IL-26 signaling pathways; JAK-STAT signaling in the regulation of Beta-cells; TAR syndrome; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; TGF-beta receptor signaling; EPO receptor signaling; Interferon type I signaling pathways; Notch signaling pathway; Serotonin HTR1 group and FOS pathway"	"114"	"0"	"21.1"	"13.6"	"20.7"	"16.2"	"23.9"	"22.3"	"34.3"	"2.1"	"231.8"	"265.8"	"490.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Q9"	"General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"886"	"101.2"	"5.07"	"380.42"	"4.24"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13181"	"9330"	"ENSG00000119041"	"GTF3C3"	"hsa:9330; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97; Q9Y5Q9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	"13.6"	"14.3"	"18.2"	"14.6"	"16.1"	"16.6"	"39.7"	"6.3"	"271.1"	"243.9"	"583.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRN9"	"rRNA N6-adenosine-methyltransferase METTL5 OS=Homo sapiens OX=9606 GN=METTL5 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"209"	"23.7"	"6.68"	"344.24"	"4.24"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05175"	"29081"	"ENSG00000138382"	"METTL5"	"D3DPC9; hsa:29081; Q9NRN9; Q9NVX1"	""	""	"0"	"0"	"3.5"	"0.0"	"6.2"	"3.0"	"5.7"	"3.7"	"9.7"	"0.0"	"223.9"	"239.9"	"615.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15758"	"Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"541"	"56.6"	"5.48"	"400.37"	"4.23"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00375"	"6510"	"ENSG00000105281"	"SLC1A5"	"A8K9H5; B4DR77; B4DWS4; B7ZB81; D0EYG6; E9PC01; hsa:6510; O95720; Q15758; Q96RL9; Q9BWQ3; Q9UNP2"	"RHOH GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Amino acid transport across the plasma membrane"	"TYROBP causal network in microglia; mRNA, protein, and metabolite inducation pathway by cyclosporin A; Metabolic reprogramming in colon cancer; Ferroptosis; Amino acid metabolism in triple-negative breast cancer cells"	"11"	"0"	"14.4"	"6.1"	"19.6"	"17.8"	"13.4"	"11.9"	"19.0"	"1.5"	"112.8"	"108.5"	"224.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N122"	"Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1335"	"148.9"	"6.89"	"459.48"	"4.23"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf02985, Pf14538"	"57521"	"ENSG00000141564"	"RPTOR"	"B2RN36; C6KEF2; F5H7J5; hsa:57521; Q8N122; Q8N4V9; Q8TB32; Q9P2P3"	"Regulation of PTEN gene transcription; TP53 Regulates Metabolic Genes; Amino acids regulate mTORC1; mTORC1-mediated signalling; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; HSF1-dependent transactivation"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; CAMKK2 pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways"	"33"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95568"	"Histidine protein methyltransferase 1 homolog OS=Homo sapiens OX=9606 GN=METTL18 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"372"	"42.1"	"6.76"	"407.61"	"4.22"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13489"	"92342"	"ENSG00000171806"	"METTL18"	"B2R9T5; hsa:92342; O95568"	""	""	"0"	"0"	"0.0"	"0.0"	"2.7"	"0.0"	"1.9"	"2.7"	"6.4"	"0.0"	"59.8"	"66.9"	"150.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15532"	"Protein SSXT OS=Homo sapiens OX=9606 GN=SS18 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"418"	"45.9"	"6.46"	"598.60"	"4.22"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05030"	"6760"	"ENSG00000141380"	"SS18"	"B0YJ95; hsa:6760; Q15532; Q16404; Q4VAX1; Q9BXC6"	""	""	"0"	"0"	"19.3"	"18.1"	"21.7"	"18.4"	"16.5"	"20.6"	"51.4"	"0.0"	"128.4"	"145.4"	"262.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15213"	"WD repeat-containing protein 46 OS=Homo sapiens OX=9606 GN=WDR46 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"610"	"68.0"	"9.67"	"485.79"	"4.21"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf08149"	"9277"	"ENSG00000204221; ENSG00000206284; ENSG00000226916; ENSG00000227057; ENSG00000236222"	"WDR46"	"A6NDP5; hsa:9277; O15213; Q5HYZ0; Q5STK5; Q5STR3"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"4.3"	"0.0"	"3.3"	"2.8"	"6.0"	"5.3"	"6.3"	"0.7"	"31.9"	"33.7"	"52.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82932"	"28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"125"	"14.2"	"9.26"	"435.23"	"4.21"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01250"	"64968"	"ENSG00000243927"	"MRPS6"	"B2R573; hsa:64968; P82932; Q96Q64; Q9BSK8; Q9BW89"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"8.4"	"7.6"	"12.4"	"6.6"	"7.3"	"11.7"	"31.4"	"3.8"	"272.5"	"272.7"	"534.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N300"	"Small vasohibin-binding protein OS=Homo sapiens OX=9606 GN=SVBP PE=1 SV=1"	"0.000"	""	"23"	"1"	"2"	"1"	"66"	"7.8"	"9.16"	"385.76"	"4.20"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf15674"	"374969"	"ENSG00000177868"	"SVBP"	"A8K5P1; D3DPW7; hsa:374969; Q8N300"	"Carboxyterminal post-translational modifications of tubulin"	""	"1"	"0"	"21.7"	"16.3"	"16.8"	"22.5"	"23.0"	"26.3"	"57.7"	"1.1"	"377.1"	"374.7"	"603.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZW49"	"PAX-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAXIP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1069"	"121.3"	"6.70"	"440.08"	"4.20"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00533, Pf12738"	"22976"	"ENSG00000157212"	"PAXIP1"	"hsa:22976; O15404; Q6N099; Q6ZW49; Q6ZWH9; Q7Z315; Q86UN0; Q8N4P9; Q96HP2"	"Formation of WDR5-containing histone-modifying complexes; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Nonhomologous End-Joining (NHEJ)"	"16p11.2 proximal deletion syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Kleefstra syndrome"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00338"	"L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2"	""	""	"5"	"1"	"2"	"1"	"332"	"36.7"	"8.27"	""	"4.20"	""	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3939"	"ENSG00000134333; ENSG00000288299"	"LDHA"	"B4DKQ2; B7Z5E3; D3DQY3; F8W819; hsa:3939; P00338; Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9"	"Pyruvate metabolism"	"Cori cycle; HIF1A and PPARG regulation of glycolysis; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Orexin receptor pathway; CCL18 signaling pathway; Glucose metabolism in triple-negative breast cancer cells; Warburg effect modulated by deubiquitinating enzymes and their substrates; Lactate shuttle in glial cells; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders"	"19"	"0"	"12.0"	"0.0"	"9.3"	"7.7"	"13.3"	"14.0"	"14.6"	"0.0"	"967.6"	"640.5"	"2239.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q07866"	"Kinesin light chain 1 OS=Homo sapiens OX=9606 GN=KLC1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"573"	"65.3"	"6.20"	""	"4.20"	""	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00515, Pf13374, Pf13424"	"3831"	"ENSG00000126214"	"KLC1"	"A6NF62; F8VTM4; hsa:3831; Q07866; Q7RTM2; Q7RTM3; Q7RTM5; Q7RTP9; Q7RTQ3; Q7RTQ5; Q7RTQ6; Q86SF5; Q86TF5; Q86V74; Q86V75; Q86V76; Q86V77; Q86V78; Q86V79; Q96H62"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Signaling by ALK fusions and activated point mutants; RHO GTPases activate KTN1"	"Alzheimer's disease and miRNA effects; IL-18 signaling pathway; Alzheimer's disease"	"8"	"0"	"8.0"	"2.3"	"3.5"	"6.6"	"7.6"	"5.4"	"17.5"	"0.0"	"162.5"	"170.9"	"326.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46199"	"Translation initiation factor IF-2, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"727"	"81.3"	"7.15"	"404.03"	"4.20"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf11987"	"4528"	"ENSG00000085760"	"MTIF2"	"D6W5D0; hsa:4528; P46199"	"Mitochondrial translation initiation"	""	"1"	"0"	"4.5"	"3.8"	"7.8"	"5.8"	"6.7"	"5.6"	"11.4"	"0.0"	"189.6"	"176.9"	"331.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3X0"	"Coiled-coil domain-containing protein 9 OS=Homo sapiens OX=9606 GN=CCDC9 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"531"	"59.7"	"5.40"	"448.37"	"4.20"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity"	"Pf15266"	"26093"	"ENSG00000105321"	"CCDC9"	"hsa:26093; Q9Y3X0"	""	"IL-18 signaling pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38117"	"Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"255"	"27.8"	"8.10"	"494.44"	"4.19"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01012"	"2109"	"ENSG00000105379"	"ETFB"	"A8K766; B3KNY2; hsa:2109; P38117; Q6IBH7; Q71RF6; Q9Y3S7"	"Respiratory electron transport; Protein methylation"	""	"2"	"0"	"3.3"	"0.0"	"2.9"	"3.0"	"0.0"	"4.9"	"14.2"	"1.5"	"103.9"	"107.2"	"294.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4U2R6"	"39S ribosomal protein L51, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL51 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"128"	"15.1"	"11.27"	"391.84"	"4.19"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10244"	"51258"	"ENSG00000111639"	"MRPL51"	"hsa:51258; Q4U2R6; Q96Q57; Q9BQ36; Q9P0N7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"20.2"	"16.4"	"33.0"	"24.6"	"25.8"	"25.2"	"85.5"	"0.0"	"330.6"	"320.1"	"657.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96PV6"	"Leukocyte receptor cluster member 8 OS=Homo sapiens OX=9606 GN=LENG8 PE=1 SV=3"	""	""	"3"	"2"	"2"	"2"	"800"	"88.1"	"9.11"	""	"4.18"	""	"2"	""	"nucleus;other cell component"	""	"Pf03399"	"114823"	"ENSG00000167615; ENSG00000274305; ENSG00000276458; ENSG00000276681"	"LENG8"	"A0A087WTE7; B0VJY9; hsa:114823; Q8IZ27; Q8NCX6; Q96PV6"	""	""	"0"	"0"	"15.5"	"8.7"	"25.0"	"12.7"	"14.9"	"15.9"	"49.1"	"1.5"	"486.0"	"372.9"	"1001.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9N8"	"Probable RNA-binding protein EIF1AD OS=Homo sapiens OX=9606 GN=EIF1AD PE=1 SV=1"	"0.000"	""	"10"	"1"	"2"	"1"	"165"	"19.0"	"5.21"	"437.46"	"4.18"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"84285"	"ENSG00000175376"	"EIF1AD"	"B2R4N5; hsa:84285; Q8N9N8; Q9BSC1"	""	""	"0"	"0"	"11.0"	"10.4"	"10.6"	"14.0"	"14.5"	"18.5"	"25.3"	"1.0"	"66.3"	"68.8"	"93.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62191"	"26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"440"	"49.2"	"6.21"	"445.90"	"4.18"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5700"	"ENSG00000100764"	"PSMC1"	"B4DR63; hsa:5700; P49014; P62191; Q03527; Q6IAW0; Q6NW36; Q96AZ3"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"24.4"	"12.6"	"17.9"	"22.7"	"17.7"	"19.2"	"19.6"	"0.8"	"89.8"	"91.1"	"255.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5K1"	"CDGSH iron-sulfur domain-containing protein 2 OS=Homo sapiens OX=9606 GN=CISD2 PE=1 SV=1"	"0.000"	""	"10"	"1"	"2"	"1"	"135"	"15.3"	"9.61"	"433.68"	"4.18"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf09360, Pf10660"	"493856"	"ENSG00000145354"	"CISD2"	"hsa:493856; Q7Z3D5; Q8N5K1"	""	""	"0"	"0"	"7.0"	"8.7"	"7.6"	"6.6"	"9.9"	"8.1"	"15.8"	"2.6"	"208.8"	"210.4"	"431.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75175"	"CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"753"	"81.8"	"6.20"	"366.23"	"4.18"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04065, Pf04153"	"4849"	"ENSG00000088038; ENSG00000273943; ENSG00000274176; ENSG00000274616; ENSG00000274941; ENSG00000275979; ENSG00000276082; ENSG00000277114; ENSG00000277600; ENSG00000277615"	"CNOT3"	"hsa:4849; O75175; Q9NZN7; Q9UF76"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	""	"2"	"0"	"10.7"	"3.7"	"6.5"	"4.7"	"7.9"	"10.0"	"5.8"	"0.0"	"91.4"	"87.7"	"147.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULX6"	"A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"646"	"71.6"	"5.05"	"312.54"	"4.17"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"26993"	"ENSG00000011243"	"AKAP8L"	"B4DJ74; B5BU90; hsa:26993; O94792; Q96J58; Q9NRQ0; Q9UGM0; Q9ULX6"	"Formation of WDR5-containing histone-modifying complexes"	""	"1"	"0"	"10.5"	"7.8"	"9.4"	"11.5"	"10.9"	"16.1"	"30.3"	"0.0"	"334.6"	"343.0"	"764.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSD7"	"Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"190"	"20.7"	"9.54"	"445.19"	"4.16"	"1"	"1"	""	""	"other molecular function"	"Pf03266"	"84284"	"ENSG00000135778"	"NTPCR"	"hsa:84284; Q9BSD7"	""	""	"0"	"0"	"6.0"	"6.2"	"8.8"	"7.8"	"4.6"	"6.6"	"11.8"	"1.2"	"67.9"	"57.2"	"111.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CP9"	"AT-rich interactive domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ARID2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1835"	"197.3"	"7.42"	"349.76"	"4.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf02257"	"196528"	"ENSG00000189079"	"ARID2"	"hsa:196528; Q15KG9; Q5EB51; Q645I3; Q68CP9; Q6ZRY5; Q7Z3I5; Q86T28; Q96SJ6; Q9HCL5"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	""	"2"	"0"	"7.9"	"8.7"	"11.0"	"12.9"	"9.2"	"9.7"	"18.8"	"1.6"	"65.9"	"55.2"	"125.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49321"	"Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"788"	"85.2"	"4.30"	"499.65"	"4.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10516"	"4678"	"ENSG00000132780"	"NASP"	"A8K6H2; B4DQP3; D3DQ07; F5H3J2; hsa:4678; P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2"	""	""	"0"	"0"	"111.1"	"76.6"	"100.0"	"92.4"	"91.6"	"130.2"	"249.4"	"0.0"	"725.1"	"702.8"	"1160.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYK5"	"39S ribosomal protein L39, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL39 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"338"	"38.7"	"7.65"	"400.51"	"4.15"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	""	"54148"	"ENSG00000154719"	"MRPL39"	"C9JYA5; hsa:54148; Q32Q74; Q5QTR3; Q96Q65; Q9BSQ7; Q9BZV6; Q9NX44; Q9NYK5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"7.0"	"9.1"	"12.3"	"5.0"	"8.6"	"9.3"	"35.3"	"3.4"	"360.7"	"341.5"	"745.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25440"	"Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"801"	"88.0"	"9.09"	"425.71"	"4.15"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf17035"	"6046"	"ENSG00000204256; ENSG00000215077; ENSG00000234507; ENSG00000234704; ENSG00000235307"	"BRD2"	"A2AAU0; B0S7P0; B1AZT1; hsa:6046; O00699; O00700; P25440; Q15310; Q5STC9; Q63HQ9; Q658Y7; Q6P3U2; Q969U4"	"RUNX3 regulates p14-ARF"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VVJ2"	"Histone H2A deubiquitinase MYSM1 OS=Homo sapiens OX=9606 GN=MYSM1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"828"	"95.0"	"5.53"	"493.37"	"4.14"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf01398, Pf04433"	"114803"	"ENSG00000162601"	"MYSM1"	"A8KA54; B3KX65; hsa:114803; Q5VVJ2; Q68DD3; Q6AI53; Q7Z3G8; Q96PX3"	"Metalloprotease DUBs"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"4.7"	"3.7"	"67.0"	"47.0"	"148.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35226"	"Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"2"	"1"	"326"	"36.9"	"8.63"	"240.63"	"4.14"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13923, Pf16207"	"100532731; 648"	"ENSG00000168283"	"BMI1"	"hsa:100532731; hsa:648; P35226; Q16030; Q5T8Z3; Q96F37"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"Pleural mesothelioma; Interactions of natural killer cells in pancreatic cancer; CCL18 signaling pathway"	"12"	"0"	"9.9"	"4.9"	"8.1"	"9.7"	"10.5"	"10.4"	"31.6"	"3.9"	"289.8"	"305.8"	"576.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P27144"	"Adenylate kinase 4, mitochondrial OS=Homo sapiens OX=9606 GN=AK4 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"223"	"25.3"	"8.40"	""	"4.14"	""	"1"	"other metabolic processes;stress response;other biological processes"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"205"	"ENSG00000162433"	"AK4"	"B2R927; D3DQ62; hsa:205; P27144; Q6IBH4; Q6NXQ5; Q8IUU9"	"Interconversion of nucleotide di- and triphosphates"	"CCL18 signaling pathway"	"2"	"0"	"2.3"	"0.0"	"2.7"	"0.0"	"2.0"	"0.0"	"1.6"	"1.3"	"113.8"	"138.7"	"332.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z628"	"Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"596"	"67.7"	"9.23"	"390.87"	"4.11"	"1"	"1"	"stress response;signal transduction;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity"	"Pf00169, Pf00621"	"10276"	"ENSG00000173848"	"NET1"	"hsa:10276; Q12773; Q7Z628; Q96D82; Q99903; Q9UEN6"	"RHOA GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	"5"	"0"	"7.5"	"5.2"	"3.6"	"6.3"	"7.1"	"5.1"	"10.4"	"0.4"	"48.5"	"52.8"	"84.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96F86"	"Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"508"	"56.0"	"7.11"	"697.66"	"4.11"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03853, Pf09532, Pf12701, Pf16598"	"80153"	"ENSG00000179151"	"EDC3"	"B3KPH0; D3DW61; hsa:80153; Q96F86; Q9H797"	"mRNA decay by 5' to 3' exoribonuclease"	""	"1"	"0"	"34.1"	"22.6"	"48.4"	"42.4"	"44.2"	"33.5"	"89.8"	"2.7"	"576.3"	"605.3"	"1211.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1K2"	"Polyamine-modulated factor 1 OS=Homo sapiens OX=9606 GN=PMF1 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"205"	"23.3"	"5.49"	"375.60"	"4.11"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03980"	"100527963; 11243"	"ENSG00000160783"	"PMF1"	"A8K0C5; hsa:100527963; hsa:11243; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9; Q6P1K2; Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"0.0"	"0.0"	"3.1"	"2.5"	"0.0"	"4.8"	"10.0"	"6.4"	"244.6"	"213.0"	"522.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVC6"	"Transmembrane protein 109 OS=Homo sapiens OX=9606 GN=TMEM109 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"243"	"26.2"	"10.48"	"439.87"	"4.10"	"1"	"1"	"stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"transporter activity"	"Pf14965"	"79073"	"ENSG00000110108"	"TMEM109"	"hsa:79073; Q9BVC6"	""	""	"0"	"0"	"2.7"	"2.6"	"3.0"	"4.6"	"2.4"	"2.8"	"11.1"	"0.0"	"41.8"	"45.3"	"94.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VWN6"	"Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"2430"	"268.7"	"5.90"	"566.29"	"4.10"	"1"	"1"	"cell organization and biogenesis"	"cytosol;nucleus"	""	"Pf12480, Pf12509"	"54906"	"ENSG00000108021"	"TASOR2"	"hsa:54906; Q2YD91; Q5VWN5; Q5VWN6; Q6ZRQ8; Q8IVG4; Q9BUZ7; Q9H5J9; Q9H7A4; Q9H996; Q9NXA1"	""	""	"0"	"0"	"5.0"	"5.2"	"2.7"	"8.5"	"6.8"	"5.3"	"13.0"	"1.1"	"83.0"	"87.5"	"166.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47914"	"60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"2"	"159"	"17.7"	"11.66"	"670.78"	"4.09"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01779"	"6159"	"ENSG00000162244"	"RPL29"	"A8K0H3; B2R4M8; hsa:6159; P47914; Q6IPY3"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"196.3"	"152.9"	"186.4"	"163.7"	"133.5"	"160.5"	"900.6"	"0.0"	"1563.0"	"1604.8"	"2429.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61586"	"Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"193"	"21.8"	"6.10"	"404.09"	"4.09"	"1"	"1"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"387"	"ENSG00000067560"	"RHOA"	"hsa:387; P06749; P61586; Q53HM4; Q5U024; Q9UDJ0; Q9UEJ4"	"Neutrophil degranulation; RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHO GTPases Activate Formins; EPHB-mediated forward signaling; GPVI-mediated activation cascade; PI3K/AKT activation; VEGFA-VEGFR2 Pathway; ERBB2 Regulates Cell Motility; RHO GTPases activate CIT; G beta:gamma signalling through PI3Kgamma; PCP/CE pathway; RHO GTPases Activate Rhotekin and Rhophilins; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Sema4D mediated inhibition of cell attachment and migration; Ovarian tumor domain proteases; SLIT2:ROBO1 increases RHOA activity; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Axonal growth stimulation; Axonal growth inhibition (RHOA activation); RHO GTPases activate KTN1"	"Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Leptin signaling pathway; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Focal adhesion; G protein signaling pathways; Wnt signaling pathway; Hypothetical craniofacial development pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Fibrin complement receptor 3 signaling pathway; Wnt signaling in kidney disease; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Joubert syndrome; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; PtdIns(4,5)P2 in cytokinesis pathway; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; G13 signaling pathway; 13q12.12 copy number variation; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"70"	"0"	"16.3"	"14.5"	"13.6"	"17.4"	"19.1"	"11.4"	"14.0"	"3.2"	"100.2"	"80.6"	"199.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13405"	"39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"166"	"19.2"	"9.45"	"338.92"	"4.09"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05046"	"740"	"ENSG00000149792"	"MRPL49"	"B2R4G6; hsa:740; Q13405"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"20.1"	"15.0"	"34.5"	"25.2"	"24.2"	"28.4"	"95.7"	"0.0"	"320.4"	"344.6"	"387.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWU1"	"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OS=Homo sapiens OX=9606 GN=OXSM PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"459"	"48.8"	"7.66"	"331.81"	"4.09"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00109, Pf02801"	"54995"	"ENSG00000151093"	"OXSM"	"hsa:54995; Q9NWU1"	""	"Mitochondrial fatty acid synthesis pathway"	"1"	"0"	"9.0"	"3.3"	"5.1"	"10.2"	"10.0"	"7.4"	"18.8"	"2.6"	"115.2"	"103.4"	"192.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4Z3"	"mRNA (2'-O-methyladenosine-N(6)-)-methyltransferase OS=Homo sapiens OX=9606 GN=PCIF1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"704"	"80.6"	"7.42"	"355.87"	"4.08"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf12237"	"63935"	"ENSG00000100982"	"PCIF1"	"E1P5P1; hsa:63935; Q54AB9; Q9H4Z3; Q9NT85"	""	""	"0"	"0"	"16.4"	"20.5"	"24.2"	"22.2"	"22.9"	"19.5"	"34.4"	"0.0"	"192.6"	"197.9"	"471.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BY65"	"Nasopharyngeal carcinoma down-regulated gene protein 1 OS=Homo sapiens OX=9606 GN=NPCDR1 PE=4 SV=2"	""	""	"12"	"1"	"3"	"1"	"106"	"12.0"	"7.88"	""	"4.08"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"5.8"	"8.4"	"9.2"	"8.1"	"8.5"	"10.1"	"24.5"	"0.9"	"463.1"	"451.7"	"973.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9L3"	"Interferon-stimulated 20 kDa exonuclease-like 2 OS=Homo sapiens OX=9606 GN=ISG20L2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"353"	"39.1"	"9.94"	"701.18"	"4.08"	"2"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf00929"	"81875"	"ENSG00000143319"	"ISG20L2"	"D3DVC6; hsa:81875; Q64KA2; Q9H9L3"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"14.8"	"10.7"	"19.0"	"14.8"	"18.4"	"19.8"	"58.8"	"2.1"	"283.4"	"268.6"	"489.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5C9Z4"	"Nucleolar MIF4G domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NOM1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"860"	"96.2"	"8.10"	"380.05"	"4.08"	"1"	"1"	"other biological processes"	"nucleus"	""	"Pf02847, Pf02854"	"64434"	"ENSG00000146909"	"NOM1"	"hsa:64434; Q5C9Z4; Q96I08"	""	""	"0"	"0"	"54.5"	"49.6"	"53.9"	"48.7"	"56.8"	"51.0"	"104.1"	"0.0"	"390.6"	"400.9"	"814.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H081"	"Protein MIS12 homolog OS=Homo sapiens OX=9606 GN=MIS12 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"205"	"24.1"	"5.69"	"424.44"	"4.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf05859"	"79003"	"ENSG00000167842"	"MIS12"	"hsa:79003; Q96N24; Q9H081"	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"15.9"	"4.8"	"10.2"	"8.4"	"8.4"	"12.9"	"39.3"	"5.9"	"402.9"	"351.4"	"743.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969S2"	"Endonuclease 8-like 2 OS=Homo sapiens OX=9606 GN=NEIL2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"332"	"36.8"	"6.79"	"535.78"	"4.07"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf06831"	"252969"	"ENSG00000154328"	"NEIL2"	"B4DFR7; hsa:252969; Q7Z3Q7; Q8N842; Q8NG52; Q969S2"	"Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway"	"Base excision repair; DNA repair pathways, full network; 8p23.1 copy number variation syndrome"	"6"	"0"	"0.0"	"3.5"	"3.1"	"2.4"	"2.5"	"0.0"	"5.6"	"0.0"	"113.7"	"95.6"	"131.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P013"	"Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2"	"0.000"	""	"7"	"1"	"2"	"1"	"229"	"26.6"	"5.71"	"418.08"	"4.06"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04889"	"51503"	"ENSG00000150316"	"CWC15"	"B2RC17; hsa:51503; Q05BV9; Q05DM1; Q9P013; Q9UI29"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"10.3"	"7.7"	"8.9"	"16.3"	"9.1"	"6.8"	"14.0"	"2.2"	"63.0"	"66.9"	"188.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q70UQ0"	"Inhibitor of nuclear factor kappa-B kinase-interacting protein OS=Homo sapiens OX=9606 GN=IKBIP PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"350"	"39.3"	"9.17"	"436.17"	"4.06"	"1"	"1"	"other biological processes"	"other membranes;ER/Golgi"	""	""	"121457"	"ENSG00000166130"	"IKBIP"	"hsa:121457; Q6ZWH4; Q70UP9; Q70UQ0; Q86V91; Q96ND2"	"Regulation of NF-kappa B signaling"	""	"1"	"0"	"6.5"	"6.4"	"7.3"	"7.7"	"9.8"	"9.3"	"18.2"	"0.0"	"156.9"	"171.2"	"394.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67775"	"Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform OS=Homo sapiens OX=9606 GN=PPP2CA PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"309"	"35.6"	"5.54"	"348.26"	"4.06"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00149"	"5515"	"ENSG00000113575"	"PPP2CA"	"hsa:5515; P05323; P13197; P67775"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Negative regulation of MAPK pathway; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"Sphingolipid pathway; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Dopamine metabolism; Mesodermal commitment pathway; Mesodermal commitment pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Cancer immunotherapy by CTLA4 blockade; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"52"	"0"	"22.1"	"19.7"	"26.5"	"22.1"	"37.3"	"27.1"	"48.3"	"0.6"	"204.3"	"208.6"	"411.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2K7"	"Lysine-specific demethylase 2A OS=Homo sapiens OX=9606 GN=KDM2A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1162"	"132.7"	"7.58"	"537.23"	"4.06"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00646, Pf02008, Pf16866, Pf17811"	"22992"	"ENSG00000173120"	"KDM2A"	"D4QA03; E9PIL6; hsa:22992; I3VM55; Q49A21; Q4G0M3; Q69YY8; Q9BVH5; Q9H7H5; Q9UK66; Q9Y2K7"	"HDMs demethylate histones"	""	"1"	"0"	"8.2"	"8.3"	"7.1"	"7.7"	"5.7"	"7.2"	"20.5"	"1.6"	"77.5"	"80.9"	"140.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P53004"	"Biliverdin reductase A OS=Homo sapiens OX=9606 GN=BLVRA PE=1 SV=2"	""	""	"8"	"1"	"1"	"1"	"296"	"33.4"	"6.44"	""	"4.05"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01408, Pf09166"	"644"	"ENSG00000106605"	"BLVRA"	"A8K747; hsa:644; O95019; P53004; Q86UX0; Q96QL4; Q9BRW8"	"Cytoprotection by HMOX1; Heme degradation"	"IL-10 anti-inflammatory signaling pathway"	"3"	"0"	"3.1"	"0.0"	"2.5"	"0.0"	"0.0"	"2.1"	"5.4"	"0.9"	"51.4"	"56.0"	"201.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49189"	"4-trimethylaminobutyraldehyde dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH9A1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"494"	"53.8"	"5.87"	"517.64"	"4.04"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00171"	"223"	"ENSG00000143149"	"ALDH9A1"	"B2R6X1; B4DXY7; B9EKV4; hsa:223; P49189; Q5VV90; Q6LCL1; Q9NZT7"	"Carnitine synthesis"	"GABA receptor signaling; Fluoroacetic acid toxicity; Opioid receptor pathways"	"4"	"0"	"65.4"	"60.1"	"63.0"	"80.5"	"62.0"	"60.4"	"70.8"	"0.0"	"155.8"	"149.1"	"277.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C19"	"EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"240"	"26.7"	"5.20"	"483.92"	"4.04"	"1"	"1"	""	"other membranes"	"other molecular function"	"Pf13499"	"79180"	"ENSG00000142634"	"EFHD2"	"hsa:79180; Q5JYW9; Q96C19"	"RHOD GTPase cycle"	""	"1"	"0"	"44.8"	"27.6"	"45.9"	"34.7"	"41.2"	"38.2"	"36.2"	"1.7"	"316.6"	"279.4"	"701.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86WR0"	"Coiled-coil domain-containing protein 25 OS=Homo sapiens OX=9606 GN=CCDC25 PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"208"	"24.5"	"6.80"	""	"4.03"	""	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"nucleic acid binding activity"	"Pf05670"	"55246"	"ENSG00000147419"	"CCDC25"	"hsa:55246; Q0P663; Q86WR0; Q96SI2; Q9NV98"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"4.6"	"1.7"	"175.8"	"192.0"	"525.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43487"	"Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"201"	"23.3"	"5.29"	"406.73"	"4.03"	"1"	"1"	"transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00638"	"5902"	"ENSG00000099901"	"RANBP1"	"hsa:5902; P43487; Q53EY3"	"Rev-mediated nuclear export of HIV RNA"	"22q11.2 copy number variation syndrome"	"2"	"0"	"163.2"	"109.0"	"182.2"	"174.4"	"162.9"	"176.0"	"166.3"	"0.0"	"598.0"	"555.7"	"1251.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HR8"	"H/ACA ribonucleoprotein complex non-core subunit NAF1 OS=Homo sapiens OX=9606 GN=NAF1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"494"	"53.7"	"4.87"	"360.17"	"4.03"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04410"	"92345"	"ENSG00000145414"	"NAF1"	"D3DP28; E9PAZ2; hsa:92345; Q96HR8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUM4"	"Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"868"	"96.0"	"6.52"	"385.32"	"4.02"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03097, Pf13949"	"10015"	"ENSG00000170248"	"PDCD6IP"	"C5MQH7; E9PFU1; hsa:10015; Q6NUS1; Q8WUM4; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5"	"Budding and maturation of HIV virion; Regulation of necroptotic cell death; Uptake and function of anthrax toxins"	"Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"5"	"0"	"2.0"	"0.0"	"2.5"	"0.0"	"0.0"	"4.6"	"4.7"	"0.0"	"28.4"	"23.4"	"82.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16333"	"Cytoplasmic protein NCK1 OS=Homo sapiens OX=9606 GN=NCK1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"377"	"42.8"	"6.47"	"385.69"	"4.02"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018, Pf14604"	"4690"	"ENSG00000158092"	"NCK1"	"B7Z751; D3DNE3; hsa:4690; P16333"	"Generation of second messenger molecules; RHOU GTPase cycle; Activation of RAC1; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; RHO GTPases Activate WASPs and WAVEs; RHOV GTPase cycle; Nephrin family interactions; DCC mediated attractive signaling; Downstream signal transduction; VEGFA-VEGFR2 Pathway"	"Pathogenic Escherichia coli infection; B cell receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Genes controlling nephrogenesis; GDNF signaling; ErbB signaling pathway; T-cell receptor signaling pathway"	"26"	"0"	"12.8"	"10.7"	"14.7"	"15.4"	"11.9"	"15.0"	"18.5"	"0.0"	"208.7"	"220.0"	"423.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7E2"	"Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"651"	"73.1"	"9.23"	"305.26"	"4.01"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00567, Pf00627, Pf08585"	"81550"	"ENSG00000083544"	"TDRD3"	"B2MWP9; hsa:81550; Q53XA6; Q6P992; Q9H7E2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VYK3"	"Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1845"	"204.2"	"7.12"	"488.21"	"4.01"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13001"	""	"ENSG00000136813"	"ECPAS"	"O15074; Q5VYK3; Q8WU82"	""	""	"0"	"0"	"2.3"	"2.4"	"2.1"	"0.0"	"2.5"	"3.3"	"11.7"	"2.7"	"84.1"	"72.4"	"155.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16881"	"Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TXNRD1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"649"	"70.9"	"7.39"	"363.25"	"4.01"	"1"	"1"	"cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462, Pf02852, Pf07992"	"7296"	"ENSG00000198431"	"TXNRD1"	"B7Z1F4; B7Z3Y8; B7Z904; E9PMY9; F5H780; hsa:7296; Q16881; Q6FI31; Q6VB40; Q6VB41; Q6VB42; Q6VBP2; Q6VBP3; Q6VBP4; Q6VBP5; Q6VBP9; Q6VBQ0; Q6YNQ1; Q76P53; Q7LA96; Q8WVC8; Q99475; Q9UES8; Q9UH79"	"Interconversion of nucleotide di- and triphosphates; PPARA activates gene expression; TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; NFE2L2 regulating anti-oxidant/detoxification enzymes; Metabolism of ingested H2SeO4 and H2SeO3 into H2Se; Uptake and function of diphtheria toxin; Metabolism of ingested MeSeO2H into MeSeH"	"Selenium micronutrient network; Selenium micronutrient network ; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway; Oxidative stress response; Ferroptosis"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32780"	"General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"548"	"62.0"	"8.66"	"843.11"	"4.00"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf03909, Pf08567"	"2965"	"ENSG00000110768; ENSG00000288114"	"GTF2H1"	"B3KXE0; D3DQY2; hsa:2965; P32780; Q6I9Y7; Q9H5K5; Q9NQD9"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	"9.8"	"5.6"	"9.1"	"9.7"	"11.9"	"9.3"	"23.3"	"0.5"	"251.6"	"247.0"	"458.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NG31"	"Kinetochore scaffold 1 OS=Homo sapiens OX=9606 GN=KNL1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2342"	"265.2"	"5.47"	"350.80"	"3.99"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf18210, Pf19221"	"57082"	"ENSG00000137812"	"KNL1"	"hsa:57082; Q8NG31; Q8NHE1; Q8WXA6; Q9HCK2; Q9NR92"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Deposition of new CENPA-containing nucleosomes at the centromere; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"7"	"0"	"19.0"	"5.7"	"18.7"	"23.1"	"17.7"	"14.2"	"24.6"	"2.0"	"269.9"	"245.5"	"480.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NVN8"	"Guanine nucleotide-binding protein-like 3-like protein OS=Homo sapiens OX=9606 GN=GNL3L PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"582"	"65.5"	"8.44"	""	"3.99"	""	"1"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf01926"	"54552"	"ENSG00000130119"	"GNL3L"	"hsa:54552; Q9NVN8"	""	""	"0"	"0"	"11.0"	"5.8"	"13.7"	"12.6"	"9.7"	"12.2"	"25.0"	"0.0"	"283.5"	"266.6"	"783.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUP7"	"tRNA:m(4)X modification enzyme TRM13 homolog OS=Homo sapiens OX=9606 GN=TRMT13 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"481"	"54.2"	"8.09"	"369.20"	"3.98"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf05206, Pf05253, Pf11722"	"54482"	"ENSG00000122435"	"TRMT13"	"hsa:54482; Q5VVL0; Q9NUP7; Q9NW65"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"2.6"	"0.0"	"2.1"	"2.4"	"0.0"	"0.0"	"1.5"	"1.0"	"51.6"	"60.1"	"124.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A1A4S6"	"Rho GTPase-activating protein 10 OS=Homo sapiens OX=9606 GN=ARHGAP10 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"786"	"89.3"	"7.18"	"434.87"	"3.98"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf00620, Pf14604, Pf16746"	"79658"	"ENSG00000071205"	"ARHGAP10"	"A1A4S6; A1L0S5; hsa:79658; Q2VPC4; Q2VPC5; Q96EV3; Q96S75"	"Regulation of PAK-2p34 activity by PS-GAP/RHG10; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle"	"Ectoderm differentiation; Ectoderm differentiation"	"6"	"0"	"18.7"	"15.4"	"23.7"	"25.0"	"23.3"	"21.1"	"40.3"	"0.0"	"387.3"	"379.8"	"675.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94887"	"FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FARP2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1054"	"119.8"	"8.79"	"391.12"	"3.98"	"1"	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"9855"	"ENSG00000006607"	"FARP2"	"B7Z6J8; F5GZ84; hsa:9855; O94887; Q53QM5; Q8WU27; Q9UFE7"	"RAC1 GTPase cycle; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"	"2q37 copy number variation syndrome; TAR syndrome"	"4"	"0"	"6.6"	"2.9"	"4.9"	"6.1"	"6.9"	"7.9"	"10.5"	"0.2"	"136.6"	"162.2"	"385.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB7"	"AF4/FMR2 family member 4 OS=Homo sapiens OX=9606 GN=AFF4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"1163"	"127.4"	"9.31"	"320.56"	"3.97"	"1"	"1"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf05110, Pf18875, Pf18876"	"27125"	"ENSG00000072364"	"AFF4"	"B2RP19; B7WPD2; hsa:27125; Q498B2; Q59FB3; Q6P592; Q8TDR1; Q9P0E4; Q9UHB7"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	""	"3"	"0"	"27.1"	"20.4"	"22.5"	"28.5"	"19.3"	"24.2"	"50.0"	"3.7"	"364.6"	"318.1"	"640.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15182"	"Centrin-3 OS=Homo sapiens OX=9606 GN=CETN3 PE=1 SV=2"	"0.000"	""	"12"	"1"	"2"	"1"	"167"	"19.5"	"4.74"	"469.88"	"3.95"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1070"	"ENSG00000153140"	"CETN3"	"hsa:1070; O15182; Q53YD2; Q9BS23"	""	"Breast cancer pathway"	"1"	"0"	"6.4"	"3.3"	"5.7"	"5.3"	"9.0"	"8.4"	"12.0"	"1.6"	"136.6"	"107.7"	"220.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82675"	"28S ribosomal protein S5, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS5 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"430"	"48.0"	"9.92"	"450.19"	"3.95"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00333, Pf03719"	"64969"	"ENSG00000144029"	"MRPS5"	"hsa:64969; P82675; Q4ZFY5; Q96LJ6; Q9BWI4; Q9BYC4"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"32.1"	"27.8"	"39.2"	"38.6"	"38.6"	"30.3"	"48.6"	"0.6"	"110.3"	"93.4"	"186.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56182"	"Ribosomal RNA processing protein 1 homolog A OS=Homo sapiens OX=9606 GN=RRP1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"461"	"52.8"	"9.33"	"376.69"	"3.94"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf05997"	"8568"	"ENSG00000160214"	"RRP1"	"hsa:8568; P56182; Q9NST5"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"19.4"	"8.7"	"20.3"	"18.6"	"20.2"	"14.6"	"47.4"	"0.9"	"194.9"	"178.2"	"359.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NHY2"	"E3 ubiquitin-protein ligase COP1 OS=Homo sapiens OX=9606 GN=COP1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"731"	"80.4"	"6.84"	"295.39"	"3.93"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf13923"	"64326"	"ENSG00000143207"	"COP1"	"E9PKI0; hsa:64326; Q504W6; Q6H103; Q8NHY2; Q9H6L7; X5D9B4"	"Autodegradation of the E3 ubiquitin ligase COP1; Neddylation"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P80303"	"Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"420"	"50.2"	"5.12"	"689.72"	"3.92"	"2"	"1"	"signal transduction"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4925"	"ENSG00000070081"	"NUCB2"	"A8K642; D3DQX5; hsa:4925; P80303; Q8NFT5; V9HW75"	""	""	"0"	"0"	"43.3"	"23.1"	"42.7"	"41.0"	"29.1"	"33.3"	"51.7"	"0.0"	"151.2"	"147.4"	"293.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KQ7"	"Histone-lysine N-methyltransferase EHMT2 OS=Homo sapiens OX=9606 GN=EHMT2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"1210"	"132.3"	"5.45"	"422.72"	"3.91"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00023, Pf00856, Pf05033"	"10919"	"ENSG00000204371; ENSG00000206376; ENSG00000227333; ENSG00000232045; ENSG00000236759; ENSG00000238134"	"EHMT2"	"B0UZY2; hsa:10919; Q14349; Q5JP83; Q5JQ92; Q5JQA1; Q5JQG3; Q6PK06; Q96KQ7; Q96MH5; Q96QD0; Q9UQL8; Q9Y331"	"Transcriptional Regulation by E2F6; PKMTs methylate histone lysines; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Regulation of TP53 Activity through Methylation; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"	"Histone modifications; Ethanol effects on histone modifications; MTHFR deficiency"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15084"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5"	"0.000"	""	"1"	"1"	"2"	"1"	"1053"	"112.9"	"6.25"	"352.04"	"3.91"	"1"	"1"	""	"cytosol;nucleus"	""	"Pf00023, Pf13637"	"23243"	"ENSG00000206560"	"ANKRD28"	"B4DES5; hsa:23243; O15084; Q1WWL4; Q29RW6; Q3B857; Q6ULS0; Q6ZT57"	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	""	"2"	"0"	"0.0"	"3.2"	"2.4"	"6.6"	"3.6"	"2.4"	"4.0"	"0.0"	"33.1"	"24.0"	"73.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NVA1"	"Ubiquinol-cytochrome-c reductase complex assembly factor 1 OS=Homo sapiens OX=9606 GN=UQCC1 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"299"	"34.6"	"8.91"	""	"3.91"	""	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;other cell component"	""	"Pf03981"	"55245"	"ENSG00000101019"	"UQCC1"	"B1AKV5; hsa:55245; Q0VF37; Q5T348; Q5T351; Q5T353; Q86YU3; Q86YU4; Q96H66; Q9H438; Q9H452; Q9H9K8; Q9H9R5; Q9NVA1"	""	"Ciliary landscape; Mitochondrial complex III assembly"	"2"	"0"	"6.4"	"5.6"	"5.2"	"4.1"	"9.0"	"4.6"	"6.1"	"1.4"	"284.3"	"245.5"	"622.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y4B4"	"Helicase ARIP4 OS=Homo sapiens OX=9606 GN=RAD54L2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1467"	"162.7"	"6.09"	""	"3.91"	""	"1"	"cell organization and biogenesis"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"23132"	"ENSG00000164080"	"RAD54L2"	"hsa:23132; Q8TB57; Q9BV54; Q9Y4B4"	""	"DYRK1A involvement regarding cell proliferation in brain development"	"1"	"0"	"2.6"	"0.0"	"0.0"	"2.0"	"0.0"	"2.4"	"3.2"	"0.0"	"30.9"	"29.6"	"74.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99714"	"3-hydroxyacyl-CoA dehydrogenase type-2 OS=Homo sapiens OX=9606 GN=HSD17B10 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"261"	"26.9"	"7.78"	""	"3.90"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00106"	"3028"	"ENSG00000072506"	"HSD17B10"	"hsa:3028; Q5H927; Q6IBS9; Q8TCV9; Q96HD5; Q99714"	"Branched-chain amino acid catabolism; tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"Alzheimer's disease and miRNA effects; Valproic acid pathway; Alzheimer's disease"	"7"	"0"	"31.8"	"32.2"	"40.6"	"29.4"	"31.1"	"27.5"	"54.3"	"0.0"	"379.3"	"392.9"	"1130.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L93"	"Kinesin-like protein KIF16B OS=Homo sapiens OX=9606 GN=KIF16B PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1317"	"151.9"	"6.16"	"433.28"	"3.89"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf00787"	"55614"	"ENSG00000089177"	"KIF16B"	"A6NKJ9; A7E2A8; B1AKG3; B1AKT7; C9JDN5; C9JI52; C9JSM8; C9JWJ7; hsa:55614; Q2TBF5; Q5HYC0; Q5HYK1; Q5JWW3; Q5TFK5; Q86VL9; Q86YS5; Q8IYU0; Q96L93; Q9BQJ8; Q9BQM0; Q9BQM1; Q9BQM5; Q9H5U0; Q9HCI2; Q9NXN9"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	""	"2"	"0"	"11.3"	"4.4"	"10.9"	"11.6"	"11.9"	"12.7"	"20.2"	"2.8"	"192.0"	"163.8"	"352.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19387"	"DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"275"	"31.4"	"4.92"	"451.06"	"3.89"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"5432"	"ENSG00000102978"	"POLR2C"	"hsa:5432; O15161; P19387"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Primary ovarian insufficiency"	"44"	"0"	"11.4"	"7.0"	"15.1"	"10.8"	"8.5"	"9.5"	"31.4"	"0.0"	"432.1"	"418.1"	"792.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIJ7"	"GTP:AMP phosphotransferase AK3, mitochondrial OS=Homo sapiens OX=9606 GN=AK3 PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"227"	"25.6"	"9.16"	"372.40"	"3.89"	"1"	"1"	"other metabolic processes;stress response"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"50808"	"ENSG00000147853"	"AK3"	"B4DP58; D3DRI1; E7ET30; hsa:50808; Q5VYW6; Q9H576; Q9HC01; Q9NPB4; Q9UIJ7"	"Factors involved in megakaryocyte development and platelet production"	""	"1"	"0"	"0.0"	"2.7"	"3.6"	"2.6"	"2.7"	"2.7"	"7.1"	"0.0"	"43.5"	"56.7"	"148.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4B6"	"DDB1- and CUL4-associated factor 1 OS=Homo sapiens OX=9606 GN=DCAF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1507"	"168.9"	"5.06"	"270.67"	"3.89"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	""	"9730"	"ENSG00000145041"	"DCAF1"	"hsa:9730; Q2YD74; Q8TBD9; Q9HCA1; Q9UG37; Q9Y4B6"	"Antigen processing: Ubiquitination & Proteasome degradation"	"Hippo-Merlin signaling dysregulation"	"2"	"0"	"8.8"	"11.4"	"7.9"	"8.0"	"14.0"	"12.8"	"23.4"	"0.0"	"167.4"	"161.4"	"357.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P30566"	"Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"484"	"54.9"	"7.11"	""	"3.88"	""	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00206, Pf10397"	"158"	"ENSG00000239900"	"ADSL"	"B0QY76; hsa:158; O75495; P30566; Q5TI34"	"Purine ribonucleoside monophosphate biosynthesis"	""	"1"	"0"	"6.7"	"7.9"	"7.2"	"7.3"	"6.9"	"7.9"	"16.1"	"1.5"	"61.6"	"77.9"	"122.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VZL5"	"Zinc finger MYM-type protein 4 OS=Homo sapiens OX=9606 GN=ZMYM4 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1548"	"172.7"	"6.84"	"395.67"	"3.88"	"1"	"1"	"cell organization and biogenesis;other biological processes"	""	"nucleic acid binding activity;other molecular function"	"Pf06467, Pf12012"	"9202"	"ENSG00000146463"	"ZMYM4"	"A0JP19; A0JP20; hsa:9202; O43308; Q5T5E1; Q5T5E2; Q5VZL5; Q7L3Q4"	""	""	"0"	"0"	"26.7"	"23.1"	"28.5"	"25.0"	"29.3"	"24.6"	"56.5"	"0.0"	"424.7"	"450.6"	"1017.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBT7"	"Alpha-catulin OS=Homo sapiens OX=9606 GN=CTNNAL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"734"	"81.8"	"6.64"	"439.95"	"3.88"	"1"	"1"	"cell adhesion;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf01044"	"8727"	"ENSG00000119326"	"CTNNAL1"	"B5BU47; hsa:8727; O76084; Q53FQ2; Q5JTQ7; Q5JTQ8; Q9UBT7; Q9Y401"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"32.8"	"36.6"	"76.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A4D1E9"	"GTP-binding protein 10 OS=Homo sapiens OX=9606 GN=GTPBP10 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"387"	"42.9"	"9.03"	"351.56"	"3.87"	"1"	"1"	"other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01018, Pf01926"	"85865"	"ENSG00000105793"	"GTPBP10"	"A4D1E9; B4DFY6; hsa:85865; Q3B7A6; Q5H9V2; Q8IXG8; Q8N982; Q8WU16; Q9BSP1; Q9Y6T6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBB5"	"Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"520"	"57.9"	"5.72"	"342.08"	"3.86"	"1"	"1"	""	""	""	"Pf07646, Pf13418, Pf13854, Pf13964"	"54758"	"ENSG00000104731"	"KLHDC4"	"D3DUN3; D3DUN4; D3DUN5; hsa:54758; Q8TBB5; Q96F29; Q9BVN3"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"4.8"	"0.0"	"224.2"	"227.1"	"493.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14188"	"Transcription factor Dp-2 OS=Homo sapiens OX=9606 GN=TFDP2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"446"	"49.2"	"6.57"	"449.85"	"3.86"	"1"	"1"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02319, Pf08781"	"7029"	"ENSG00000114126"	"TFDP2"	"B7Z8C8; B7Z8L5; D3DNG1; E9PFC3; F8WAI2; hsa:7029; Q13331; Q14187; Q14188; Q6R754; Q8WU88; Q9UG28"	"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; G1/S-Specific Transcription; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Cyclin D associated events in G1; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Oncogene Induced Senescence; Pre-NOTCH Transcription and Translation; Transcriptional Regulation by E2F6; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Activation of PUMA and translocation to mitochondria; Transcriptional regulation of granulopoiesis; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Activation of NOXA and translocation to mitochondria; Inhibition of replication initiation of damaged DNA by RB1/E2F1"	"Cell cycle; Retinoblastoma gene in cancer; G1 to S cell cycle control; DYRK1A involvement regarding cell proliferation in brain development; Alstrom syndrome"	"23"	"0"	"2.2"	"0.0"	"0.0"	"2.7"	"2.6"	"3.0"	"4.9"	"0.0"	"30.6"	"34.3"	"81.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2H6"	"Fibronectin type-III domain-containing protein 3A OS=Homo sapiens OX=9606 GN=FNDC3A PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1198"	"131.8"	"6.71"	"364.12"	"3.85"	"1"	"1"	"cell adhesion;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf00041"	"22862"	"ENSG00000102531"	"FNDC3A"	"B4DYG1; hsa:22862; Q5HYC9; Q5JVF8; Q5JVF9; Q6EVH3; Q6EVH4; Q6N020; Q6P9D5; Q6ZME4; Q9H1W1; Q9Y2H6"	""	""	"0"	"0"	"7.2"	"5.6"	"7.3"	"9.8"	"6.7"	"7.4"	"13.4"	"0.0"	"147.5"	"155.3"	"287.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16850"	"Lanosterol 14-alpha demethylase OS=Homo sapiens OX=9606 GN=CYP51A1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"503"	"56.8"	"8.53"	"352.83"	"3.85"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"9.5"	"7.4"	"9.5"	"5.6"	"10.7"	"10.7"	"13.7"	"0.0"	"170.1"	"182.3"	"331.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBL1"	"Protein O-glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=POGLUT1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"392"	"46.2"	"8.72"	"350.63"	"3.85"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf05686"	"56983"	"ENSG00000163389"	"POGLUT1"	"B2RD13; hsa:56983; Q53GJ4; Q8N2T1; Q8NBL1"	"Pre-NOTCH Processing in the Endoplasmic Reticulum"	""	"1"	"0"	"5.1"	"5.7"	"11.5"	"5.6"	"13.6"	"8.5"	"14.6"	"1.3"	"162.7"	"190.4"	"457.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0U3"	"Magnesium transporter protein 1 OS=Homo sapiens OX=9606 GN=MAGT1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"335"	"38.0"	"9.63"	"398.38"	"3.84"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle"	"transporter activity"	"Pf04756"	"84061"	"ENSG00000102158"	"MAGT1"	"B2RAR4; D3DTE3; hsa:84061; Q53G00; Q6P577; Q8NBN6; Q9H0U3"	"Neutrophil degranulation; Miscellaneous transport and binding events; Asparagine N-linked glycosylation; Maturation of spike protein"	""	"4"	"0"	"18.0"	"10.1"	"25.2"	"18.6"	"19.8"	"19.2"	"31.4"	"0.0"	"192.5"	"205.8"	"426.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12824"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 OS=Homo sapiens OX=9606 GN=SMARCB1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"385"	"44.1"	"6.23"	"431.37"	"3.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04855"	"6598"	"ENSG00000099956; ENSG00000275837"	"SMARCB1"	"hsa:6598; O75784; O95474; Q12824; Q17S11; Q38GA1; Q76N08; Q9UBH2"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"Tumor suppressor activity of SMARCB1; Thermogenesis; Modulators of TCR signaling and T cell activation; DYRK1A involvement regarding cell proliferation in brain development; Kleefstra syndrome; 10q11.21q11.23 copy number variation syndrome"	"8"	"0"	"23.9"	"17.4"	"24.0"	"25.5"	"24.4"	"23.5"	"46.3"	"0.0"	"252.3"	"257.1"	"507.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53999"	"Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"127"	"14.4"	"9.60"	"283.02"	"3.84"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02229"	"10923"	"ENSG00000113387"	"SUB1"	"hsa:10923; P53999; Q96L29"	""	""	"0"	"0"	"26.7"	"20.9"	"31.8"	"25.1"	"25.3"	"24.8"	"65.1"	"0.0"	"256.1"	"259.3"	"654.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q12849"	"G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"480"	"53.1"	"6.19"	""	"3.83"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"2926"	"ENSG00000132463"	"GRSF1"	"B3KPW0; hsa:2926; Q12849; Q4W5S5; Q6ZST3; Q8IWD6; Q8NBD2"	"Viral mRNA Translation"	"VEGFA-VEGFR2 signaling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H939"	"Proline-serine-threonine phosphatase-interacting protein 2 OS=Homo sapiens OX=9606 GN=PSTPIP2 PE=1 SV=4"	"0.000"	""	"4"	"1"	"2"	"1"	"334"	"38.8"	"8.48"	"260.40"	"3.83"	"1"	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00611"	"9050"	"ENSG00000152229"	"PSTPIP2"	"hsa:9050; Q9H939"	""	""	"0"	"0"	"16.2"	"13.7"	"26.3"	"26.2"	"15.9"	"9.1"	"33.7"	"1.8"	"90.3"	"74.0"	"162.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD3"	"39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"311"	"34.9"	"9.72"	"399.42"	"3.83"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00573"	"51073"	"ENSG00000105364"	"MRPL4"	"A6NNV7; hsa:51073; Q9BW07; Q9BYD3; Q9H4N2; Q9Y317"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"22.5"	"9.4"	"26.6"	"25.5"	"31.8"	"25.9"	"33.1"	"0.8"	"243.0"	"208.2"	"545.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12769"	"Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1436"	"162.0"	"5.50"	"426.92"	"3.83"	"1"	"1"	"other metabolic processes;transport;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf11715"	"23279"	"ENSG00000030066"	"NUP160"	"B4DYE8; B4E2J9; hsa:23279; Q08AD3; Q12769; Q7Z5X6; Q96GB3; Q9H660"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	""	"35"	"0"	"88.4"	"71.9"	"95.5"	"88.8"	"85.5"	"46.9"	"93.0"	"0.0"	"275.4"	"273.4"	"489.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43242"	"26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"534"	"60.9"	"8.44"	"328.24"	"3.82"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf08375"	"5709"	"ENSG00000108344"	"PSMD3"	"B3KMW9; B4DT72; hsa:5709; O43242; Q96EI2; Q9BQA4"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"14.4"	"6.4"	"19.7"	"11.4"	"13.4"	"13.7"	"19.8"	"0.0"	"211.9"	"199.0"	"433.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKD1"	"Glucocorticoid modulatory element-binding protein 2 OS=Homo sapiens OX=9606 GN=GMEB2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"530"	"56.4"	"5.60"	"624.39"	"3.82"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01342"	"26205"	"ENSG00000101216"	"GMEB2"	"E1P5J3; hsa:26205; Q5TDS0; Q9H431; Q9H4X7; Q9H4X8; Q9UF78; Q9UKD1; Q9ULF1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXS5"	"AP-1 complex subunit mu-1 OS=Homo sapiens OX=9606 GN=AP1M1 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"423"	"48.6"	"7.30"	"504.08"	"3.82"	"1"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00928"	"8907"	"ENSG00000072958"	"AP1M1"	"hsa:8907; Q4TTY5; Q9BXS5"	"Lysosome Vesicle Biogenesis; Neutrophil degranulation; MHC class II antigen presentation; Golgi Associated Vesicle Biogenesis; Nef mediated downregulation of MHC class I complex cell surface expression"	""	"5"	"0"	"16.2"	"13.5"	"15.0"	"16.0"	"12.8"	"15.6"	"27.6"	"1.5"	"189.9"	"204.0"	"432.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX55"	"Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2"	"0.000"	""	"23"	"2"	"5"	"2"	"129"	"14.7"	"4.93"	"2046.50"	"3.81"	"2"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04419, Pf19026"	"100137436; 101127706; 104002286; 104679625; 105491324; 105549422; 105588143; 108521295; 25764; 713266"	"ENSCATG00000038565; ENSGGOG00000014809; ENSMFAG00000057677; ENSMLEG00000000898; ENSMMUG00000022768; ENSMNEG00000018318; ENSPANG00000018102; ENSPPAG00000034659; ENSPTEG00000009792; ENSPTEG00000019135; ENSPTRG00000038721; ENSRBIG00000028237; ENSRROG00000039445; ENSTGEG00000007663"	"HYPK; LOC113219833"	"A0A024R5Q1; A0A1D5R5K3; A0A2I2YQJ1; A0A2J8NTT0; A0A2K5N035; A0A2K5TR12; A0A2K5XAQ0; A0A2K6AXP0; A0A2K6KBN5; A0A2K6QRU2; A0A2R9B6N1; A0A663DGD1; A0A6D2Y1W8; A0A8C9GZF6; A0A8D2ERJ4; A0A8J8XMG0; A9X1C4; F7GC11; G7MX15; G7PB77; H2Q9B3; hsa:25764; mcc:713266; mleu:105549422; mni:105491324; panu:100137436; ptr:104002286; rbb:108521295; rro:104679625"	""	""	"0"	"0"	"13.7"	"4.3"	"17.9"	"13.6"	"13.7"	"13.9"	"33.0"	"5.4"	"730.8"	"697.5"	"1519.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13233"	"Mitogen-activated protein kinase kinase kinase 1 OS=Homo sapiens OX=9606 GN=MAP3K1 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1512"	"164.4"	"7.74"	"407.63"	"3.79"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"4214"	"ENSG00000095015"	"MAP3K1"	"hsa:4214; Q13233"	"FCERI mediated MAPK activation; MyD88:MAL(TIRAP) cascade initiated on plasma membrane; TRAF6 mediated NF-kB activation; TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation; MyD88 cascade initiated on plasma membrane"	"IL-1 signaling pathway; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Apoptosis; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; Apoptosis modulation by HSP70; Novel intracellular components of RIG-I-like receptor pathway; Angiopoietin-like protein 8 regulatory pathway; BMP signaling in eyelid development; Oxidative damage response; p38 MAPK signaling pathway; MAPK cascade; EGF/EGFR signaling pathway; Vitamin D in inflammatory diseases; Signal transduction through IL1R; Hepatitis B infection; Insulin signaling; MAP3K1 role in promoting and blocking gonadal determination; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; Interferon type I signaling pathways; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"31"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07384"	"Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"714"	"81.8"	"5.67"	"394.02"	"3.79"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00648, Pf01067, Pf13833"	"823"	"ENSG00000014216"	"CAPN1"	"hsa:823; P07384; Q2TTR0; Q6DHV4"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Neutrophil degranulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"Integrin-mediated cell adhesion; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"7"	"0"	"5.3"	"0.0"	"7.7"	"7.2"	"5.2"	"3.1"	"17.1"	"0.0"	"194.4"	"175.1"	"479.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6U6"	"Breast carcinoma-amplified sequence 3 OS=Homo sapiens OX=9606 GN=BCAS3 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"928"	"101.2"	"6.70"	"418.59"	"3.78"	"1"	"1"	"cell-cell signaling;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf12490"	"54828"	"ENSG00000141376"	"BCAS3"	"hsa:54828; Q17RM0; Q6KF21; Q8IXI6; Q8NDR8; Q8TDL9; Q8TDM1; Q8WY55; Q9BVF0; Q9H6U6; Q9H957; Q9H9Y9; Q9NXP4"	""	"Ectoderm differentiation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14919"	"Dr1-associated corepressor OS=Homo sapiens OX=9606 GN=DRAP1 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"205"	"22.3"	"5.17"	"309.62"	"3.77"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"10589"	"ENSG00000175550"	"DRAP1"	"hsa:10589; Q13448; Q14919"	"Signaling by NODAL; Signaling by Activin"	""	"2"	"0"	"13.7"	"10.1"	"11.9"	"9.2"	"14.0"	"11.0"	"17.5"	"1.5"	"132.6"	"124.0"	"388.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P015"	"39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"296"	"33.4"	"10.01"	"488.80"	"3.76"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00828"	"29088"	"ENSG00000137547"	"MRPL15"	"hsa:29088; Q96Q54; Q9H0Y1; Q9P015"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"74.1"	"66.8"	"74.6"	"71.8"	"83.5"	"75.8"	"117.2"	"1.8"	"351.4"	"345.2"	"662.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y223"	"Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Homo sapiens OX=9606 GN=GNE PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"722"	"79.2"	"6.80"	"430.48"	"3.75"	"1"	"1"	"cell adhesion;other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00480, Pf02350"	"10020"	"ENSG00000159921"	"GNE"	"A6PZH2; A6PZH3; A7UNU7; B2R6E1; B7Z372; B7Z428; D3DRP7; F5H499; H0YFA7; hsa:10020; Q0VA94; Q9Y223"	"Sialic acid metabolism; Defective GNE causes sialuria, NK and IBM2"	""	"2"	"0"	"12.5"	"8.7"	"8.3"	"6.8"	"6.1"	"9.0"	"16.8"	"2.8"	"108.0"	"106.9"	"282.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06481"	"Amyloid-like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"763"	"86.9"	"4.79"	"373.43"	"3.75"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00014, Pf02177, Pf10515, Pf12924, Pf12925"	"334"	"ENSG00000084234"	"APLP2"	"B3KXX9; H7BXI4; hsa:334; Q06481; Q13861; Q14594; Q14662; Q71U10; Q7M4L3; Q9BT36"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Platelet degranulation"	"Splicing factor NOVA regulated synaptic proteins"	"4"	"0"	"2.4"	"3.1"	"3.2"	"3.0"	"4.1"	"0.0"	"11.1"	"0.0"	"81.2"	"53.7"	"164.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UBF8"	"Phosphatidylinositol 4-kinase beta OS=Homo sapiens OX=9606 GN=PI4KB PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"816"	"91.3"	"6.25"	""	"3.75"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00454"	"5298"	"ENSG00000143393"	"PI4KB"	"B4DGI2; hsa:5298; O15096; P78405; Q5VWB9; Q5VWC0; Q5VWC1; Q9BWR6; Q9UBF8"	"Synthesis of PIPs at the Golgi membrane"	""	"1"	"0"	"2.2"	"4.6"	"5.7"	"2.6"	"3.8"	"2.2"	"3.8"	"0.0"	"64.1"	"59.3"	"125.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NIH7"	"Protein unc-119 homolog B OS=Homo sapiens OX=9606 GN=UNC119B PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"251"	"28.1"	"5.68"	"447.06"	"3.74"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytosol;other cell component"	"other molecular function"	"Pf05351"	"84747"	"ENSG00000175970"	"UNC119B"	"A6NIH7; hsa:84747"	"Trafficking of myristoylated proteins to the cilium"	""	"1"	"0"	"5.5"	"3.9"	"11.8"	"9.1"	"4.5"	"7.2"	"16.4"	"0.0"	"124.3"	"129.6"	"419.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ME7"	"Zinc finger protein 512 OS=Homo sapiens OX=9606 GN=ZNF512 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"567"	"64.6"	"9.76"	"632.36"	"3.72"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"84450"	"ENSG00000243943"	"ZNF512"	"B4DSM5; hsa:84450; Q53RZ7; Q86XK6; Q96JM0; Q96ME7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8W4"	"Pleckstrin homology domain-containing family F member 2 OS=Homo sapiens OX=9606 GN=PLEKHF2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"249"	"27.8"	"8.21"	"373.51"	"3.72"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00169, Pf01363"	"79666"	"ENSG00000175895"	"PLEKHF2"	"hsa:79666; Q9H8W4"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.8"	"0.0"	"232.3"	"221.9"	"376.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPT8"	"Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1303"	"140.2"	"6.27"	"372.03"	"3.71"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608, Pf18044"	"23211"	"ENSG00000130749"	"ZC3H4"	"hsa:23211; Q9UPT8; Q9Y420"	""	""	"0"	"0"	"11.5"	"9.5"	"16.0"	"12.0"	"13.7"	"11.0"	"17.6"	"2.7"	"87.7"	"74.6"	"177.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5K6"	"CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"639"	"71.4"	"6.40"	"275.54"	"3.71"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00018, Pf14604"	"23607"	"ENSG00000198087"	"CD2AP"	"A6NL34; hsa:23607; Q5VYA3; Q9UG97; Q9Y5K6"	"Nephrin family interactions"	"Primary focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome; Genes controlling nephrogenesis; GDNF signaling"	"5"	"0"	"6.6"	"7.4"	"9.6"	"8.8"	"10.5"	"11.0"	"21.2"	"0.0"	"145.8"	"138.1"	"286.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK41"	"Vacuolar protein sorting-associated protein 28 homolog OS=Homo sapiens OX=9606 GN=VPS28 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"221"	"25.4"	"5.54"	"325.56"	"3.70"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03997"	"51160"	"ENSG00000160948; ENSG00000285339"	"VPS28"	"hsa:51160; Q86VK0; Q9UK41"	"HCMV Late Events; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy"	"7q11.23 copy number variation syndrome"	"6"	"0"	"15.2"	"11.5"	"24.5"	"21.4"	"25.8"	"13.0"	"26.7"	"0.0"	"214.5"	"225.8"	"465.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T447"	"E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"861"	"97.1"	"5.64"	"609.26"	"3.70"	"1"	"1"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00632, Pf03256"	"79654"	"ENSG00000126107"	"HECTD3"	"B3KPV7; B3KRH4; hsa:79654; Q5T447; Q5T448; Q9H783"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.3"	"2.3"	"4.0"	"0.0"	"35.6"	"31.1"	"69.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ89"	"Protein C12orf4 OS=Homo sapiens OX=9606 GN=C12orf4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"552"	"63.8"	"6.37"	"315.03"	"3.70"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf10154"	"57102"	"ENSG00000047621"	"C12orf4"	"D3DUQ8; hsa:57102; Q6MZH5; Q9NQ89"	""	""	"0"	"0"	"6.5"	"4.7"	"7.0"	"2.1"	"9.5"	"6.7"	"9.0"	"0.0"	"103.4"	"104.7"	"209.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5PSV4"	"Breast cancer metastasis-suppressor 1-like protein OS=Homo sapiens OX=9606 GN=BRMS1L PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"323"	"37.6"	"5.15"	"311.88"	"3.69"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08598"	"84312"	"ENSG00000100916"	"BRMS1L"	"A6NFW5; A6NH45; B2RD65; hsa:84312; Q5PSV4; Q9BRI4"	""	""	"0"	"0"	"0.0"	"0.0"	"5.0"	"4.4"	"3.9"	"2.6"	"8.6"	"0.0"	"59.1"	"60.2"	"129.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NT62"	"Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"314"	"35.8"	"4.74"	"341.51"	"3.69"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf03987"	"64422"	"ENSG00000144848"	"ATG3"	"hsa:64422; Q6PKC5; Q9H6L9; Q9NT62"	"Macroautophagy"	"Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; Clock-controlled autophagy in bone metabolism"	"5"	"0"	"16.0"	"18.6"	"15.0"	"11.5"	"20.8"	"23.5"	"29.7"	"0.0"	"141.8"	"135.7"	"228.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZU65"	"Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1347"	"146.0"	"9.19"	"366.23"	"3.69"	"1"	"1"	""	"nucleus"	""	"Pf08729, Pf14075"	"254048"	"ENSG00000157741"	"UBN2"	"A4D1S2; hsa:254048; Q2YDY4; Q6P1K0; Q6ZU65; Q86XN9; Q8N7D1"	""	""	"0"	"0"	"11.5"	"8.8"	"13.8"	"11.6"	"8.0"	"11.3"	"30.2"	"1.9"	"191.9"	"186.6"	"390.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07737"	"Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2"	"0.000"	""	"11"	"1"	"2"	"1"	"140"	"15.0"	"8.27"	"306.41"	"3.69"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5216"	"ENSG00000108518"	"PFN1"	"hsa:5216; P07737; Q53Y44"	"RHO GTPases Activate Formins; Platelet degranulation ; PCP/CE pathway; Signaling by ROBO receptors"	"Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Burn wound healing; Regulation of actin cytoskeleton; G13 signaling pathway"	"9"	"0"	"15.5"	"20.9"	"28.0"	"15.5"	"18.1"	"17.0"	"37.9"	"0.0"	"124.1"	"131.2"	"198.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13596"	"Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"522"	"59.0"	"5.15"	""	"3.68"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6642"	"ENSG00000028528"	"SNX1"	"A6NM19; A8K6T7; H0Y2M5; hsa:6642; O60750; O60751; Q13596; Q6ZRJ8"	""	""	"0"	"0"	"6.4"	"5.2"	"6.7"	"8.1"	"4.3"	"6.2"	"25.1"	"2.7"	"133.7"	"128.7"	"347.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5VTE6"	"Protein angel homolog 2 OS=Homo sapiens OX=9606 GN=ANGEL2 PE=2 SV=1"	""	""	"5"	"1"	"1"	"1"	"544"	"62.3"	"7.81"	""	"3.68"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372, Pf19339"	"90806"	"ENSG00000174606"	"ANGEL2"	"B7Z2U4; D3DTA3; hsa:90806; Q5VTE6; Q86X13; Q8NHH3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NR56"	"Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"388"	"41.8"	"8.90"	""	"3.68"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608"	"4154"	"ENSG00000152601"	"MBNL1"	"E9PBW7; hsa:4154; O43311; O43797; Q86UV8; Q86UV9; Q96P92; Q96RE3; Q9NR56"	""	"Adipogenesis"	"1"	"0"	"5.7"	"3.4"	"3.4"	"6.0"	"4.8"	"8.0"	"12.3"	"1.1"	"66.9"	"61.6"	"114.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z392"	"Trafficking protein particle complex subunit 11 OS=Homo sapiens OX=9606 GN=TRAPPC11 PE=1 SV=2"	"0.000"	""	"4"	"3"	"4"	"3"	"1133"	"128.8"	"7.14"	"1508.92"	"3.67"	"3"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf11817, Pf12742"	"60684"	"ENSG00000168538"	"TRAPPC11"	"A4QPB8; B2RCD6; hsa:60684; Q5U5I7; Q6FI73; Q7Z392; Q86T25; Q9H0L1; Q9H5K9; Q9H8Q1; Q9H9I7"	"RAB GEFs exchange GTP for GDP on RABs"	"Genes related to primary cilium development (based on CRISPR)"	"2"	"0"	"2.5"	"10.1"	"12.2"	"8.1"	"10.4"	"6.4"	"33.6"	"4.1"	"401.1"	"386.5"	"774.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIA9"	"Exportin-7 OS=Homo sapiens OX=9606 GN=XPO7 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"1087"	"123.8"	"6.32"	"436.11"	"3.67"	"1"	"1"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf03810"	"23039"	"ENSG00000130227"	"XPO7"	"hsa:23039; O94846; Q6PJK9; Q8NEK7; Q9UIA9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07195"	"L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"334"	"36.6"	"6.05"	"493.43"	"3.67"	"1"	"1"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3945"	"ENSG00000111716"	"LDHB"	"hsa:3945; P07195"	"Pyruvate metabolism"	"Clear cell renal cell carcinoma pathways; CCL18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"5"	"0"	"76.7"	"65.6"	"120.0"	"92.0"	"87.8"	"68.2"	"96.2"	"0.7"	"277.1"	"278.2"	"551.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28074"	"Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"263"	"28.5"	"6.92"	"407.96"	"3.67"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5693"	"ENSG00000100804"	"PSMB5"	"B2R4N9; B4DUM9; D3DS43; E9PAV2; hsa:5693; P28074; Q16242; Q6PEW2; Q7Z3B5; Q86T01; Q9TNN9"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62891"	"60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2"	"0.000"	""	"20"	"1"	"2"	"1"	"51"	"6.4"	"12.56"	"392.93"	"3.66"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00832"	"6170"	"ENSG00000198918"	"RPL39"	"hsa:6170; P02404; P39025; P62891; Q9BYF2"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"61.3"	"33.5"	"61.7"	"59.6"	"58.7"	"44.3"	"116.1"	"2.1"	"241.9"	"195.1"	"434.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3L5"	"Ras-related protein Rap-2c OS=Homo sapiens OX=9606 GN=RAP2C PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"183"	"20.7"	"4.94"	"453.00"	"3.66"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"57826"	"ENSG00000123728"	"RAP2C"	"B3KWD6; hsa:57826; Q5H9H9; Q9BTS0; Q9Y3L5"	"Neutrophil degranulation"	""	"1"	"0"	"9.6"	"9.8"	"14.4"	"8.8"	"11.2"	"11.4"	"26.1"	"2.8"	"171.1"	"155.8"	"307.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q05707"	"Collagen alpha-1(XIV) chain OS=Homo sapiens OX=9606 GN=COL14A1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"1796"	"193.4"	"5.30"	""	"3.66"	""	"1"	"cell adhesion;cell organization and biogenesis"	"extracellular matrix;ER/Golgi;other cell component"	"extracellular structural activity;other molecular function"	"Pf00041, Pf00092, Pf01391"	"7373"	"ENSG00000187955"	"COL14A1"	"B2RU07; hsa:7373; O00260; O00261; O00262; Q05707; Q05708; Q5XJ18; Q96C67; Q9UDF6"	"Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Collagen chain trimerization"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y5L4"	"Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1"	""	""	"12"	"1"	"1"	"1"	"95"	"10.5"	"8.18"	""	"3.65"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02953"	"26517"	"ENSG00000099800"	"TIMM13"	"hsa:26517; P62206; Q9UHL8; Q9WTL1; Q9Y5L4"	"Mitochondrial protein import"	""	"1"	"0"	"0.0"	"0.0"	"7.7"	"4.5"	"2.9"	"0.0"	"17.7"	"3.2"	"238.4"	"221.3"	"506.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UY8"	"5'-nucleotidase domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NT5DC3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"548"	"63.4"	"8.31"	"241.27"	"3.65"	"1"	"1"	""	"cytosol;other cell component"	"other molecular function"	"Pf05761"	"51559"	"ENSG00000111696"	"NT5DC3"	"hsa:51559; Q86UY8; Q9NUM7; Q9P2T2; Q9P2T3"	""	""	"0"	"0"	"17.2"	"9.0"	"27.6"	"16.2"	"24.4"	"15.7"	"27.8"	"0.8"	"219.3"	"212.2"	"702.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61962"	"DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"342"	"38.9"	"5.52"	"342.93"	"3.65"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"10238"	"ENSG00000136485"	"DCAF7"	"B4E039; D3DU14; hsa:10238; O15491; P61962; Q9DAE4"	"Neddylation; Association of TriC/CCT with target proteins during biosynthesis"	"Ciliary landscape; DYRK1A involvement regarding cell proliferation in brain development"	"4"	"0"	"17.2"	"8.7"	"18.8"	"21.0"	"15.7"	"15.3"	"59.0"	"3.6"	"213.5"	"203.1"	"357.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42566"	"Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"896"	"98.6"	"4.64"	"406.03"	"3.64"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"2060"	"ENSG00000085832"	"EPS15"	"B2R8J7; D3DPJ2; hsa:2060; P42566; Q5SRH4"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; EGF/EGFR signaling pathway"	"8"	"0"	"18.2"	"10.8"	"16.9"	"16.2"	"15.9"	"14.6"	"17.7"	"0.8"	"54.3"	"53.8"	"109.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02218"	"2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1023"	"115.9"	"6.86"	"368.89"	"3.63"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676, Pf02779, Pf16078, Pf16870"	"4967"	"ENSG00000105953"	"OGDH"	"B4E2U9; D3DVL0; E9PBM1; hsa:4967; Q02218; Q96DD3; Q9UDX0"	"Lysine catabolism; Glyoxylate metabolism and glycine degradation; Citric acid cycle (TCA cycle)"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Thiamine metabolic pathways; 7q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"8"	"0"	"96.8"	"83.0"	"90.0"	"92.7"	"79.2"	"89.1"	"73.5"	"9.7"	"181.2"	"167.4"	"346.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NXL9"	"DNA helicase MCM9 OS=Homo sapiens OX=9606 GN=MCM9 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1143"	"127.2"	"7.74"	""	"3.63"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf17207, Pf17855"	"254394"	"ENSG00000111877"	"MCM9"	"B4DR30; B9DI77; hsa:254394; Q2KHJ0; Q8N5S5; Q9HCV5; Q9NXL9"	""	"Ciliary landscape; Primary ovarian insufficiency"	"2"	"0"	"14.3"	"9.1"	"10.2"	"12.1"	"10.7"	"11.6"	"27.1"	"0.6"	"111.6"	"117.4"	"261.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6Y288"	"Beta-1,3-glucosyltransferase OS=Homo sapiens OX=9606 GN=B3GLCT PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"498"	"56.5"	"7.50"	"289.66"	"3.62"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf02434"	"145173"	"ENSG00000187676"	"B3GLCT"	"A8K5F8; hsa:145173; Q5W0H2; Q6NUI3; Q6Y288"	"Defective B3GALTL causes PpS; O-glycosylation of TSR domain-containing proteins"	""	"2"	"0"	"8.7"	"6.5"	"9.5"	"9.1"	"10.1"	"12.6"	"19.0"	"4.1"	"225.9"	"211.6"	"398.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q00325"	"Phosphate carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLC25A3 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"362"	"40.1"	"9.38"	""	"3.62"	""	"1"	"transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"5250"	"ENSG00000075415"	"SLC25A3"	"B3KS34; hsa:5250; Q00325; Q7Z7N7; Q96A03"	""	""	"0"	"0"	"19.3"	"14.8"	"13.7"	"13.5"	"16.9"	"15.3"	"22.8"	"3.8"	"246.8"	"264.8"	"444.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14807"	"Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5"	"0.000"	""	"2"	"1"	"2"	"1"	"665"	"73.2"	"9.45"	"394.39"	"3.61"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225, Pf12836"	"3835"	"ENSG00000079616"	"KIF22"	"B2R5M0; B7Z265; hsa:3835; O60845; O94814; Q14807; Q53F58; Q9BT46"	"MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"16p11.2 proximal deletion syndrome"	"4"	"0"	"28.4"	"23.2"	"34.1"	"29.8"	"41.6"	"30.3"	"53.9"	"0.0"	"641.3"	"642.6"	"1145.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16342"	"Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"344"	"38.6"	"5.38"	"295.49"	"3.61"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01753, Pf04194"	"5134"	"ENSG00000071994"	"PDCD2"	"E9PCU7; F5GYS7; hsa:5134; Q16342; Q58HM9; Q58HN0; Q9UH12"	""	""	"0"	"0"	"6.1"	"2.9"	"5.9"	"3.6"	"2.9"	"1.8"	"13.5"	"0.1"	"192.5"	"180.6"	"256.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P78537"	"Biogenesis of lysosome-related organelles complex 1 subunit 1 OS=Homo sapiens OX=9606 GN=BLOC1S1 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"153"	"17.3"	"9.33"	""	"3.61"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	""	"Pf06320"	"2647"	"ENSG00000135441"	"BLOC1S1"	"A1L4Q9; hsa:2647; P78537; Q6NZ45"	"Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis"	"Alstrom syndrome"	"3"	"0"	"3.0"	"0.0"	"1.8"	"3.1"	"2.7"	"2.8"	"3.2"	"0.2"	"95.1"	"97.1"	"192.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H4Q3"	"PR domain zinc finger protein 13 OS=Homo sapiens OX=9606 GN=PRDM13 PE=2 SV=2"	""	""	"6"	"1"	"1"	"1"	"707"	"73.9"	"8.73"	""	"3.60"	""	"1"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"59336"	"ENSG00000112238"	"PRDM13"	"hsa:59336; Q5TGC1; Q5TGC2; Q9H4Q3"	""	""	"0"	"0"	"26.2"	"42.6"	"17.6"	"21.8"	"18.9"	"29.4"	"113.8"	"0.0"	"263.6"	"272.0"	"355.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5FBB7"	"Shugoshin 1 OS=Homo sapiens OX=9606 GN=SGO1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"561"	"64.2"	"9.16"	"361.22"	"3.60"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07557, Pf07558"	"151648"	"ENSG00000129810"	"SGO1"	"hsa:151648; Q588H5; Q5FBB4; Q5FBB5; Q5FBB6; Q5FBB7; Q5FBB8; Q8N579; Q8WVL0; Q9BVA8; Q9H275"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Cohesin complex - Cornelia de Lange syndrome"	"7"	"0"	"4.8"	"4.3"	"10.3"	"4.9"	"5.7"	"4.4"	"10.1"	"2.1"	"53.7"	"50.6"	"153.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62487"	"DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"172"	"19.3"	"5.54"	"301.25"	"3.60"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf03876"	"5436"	"ENSG00000168002"	"POLR2G"	"B2R5C0; hsa:5436; P52433; P62487; Q2M1Z4"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"43"	"0"	"15.9"	"17.2"	"17.8"	"12.4"	"17.3"	"16.9"	"34.6"	"0.0"	"178.4"	"161.8"	"330.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08754"	"Guanine nucleotide-binding protein G(i) subunit alpha OS=Homo sapiens OX=9606 GN=GNAI3 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"1"	"354"	"40.5"	"5.69"	"587.17"	"3.59"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2773"	"ENSG00000065135"	"GNAI3"	"hsa:2773; P08754; P17539; Q5TZX1"	"G alpha (i) signalling events; G alpha (z) signalling events; Adenylate cyclase inhibitory pathway; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production"	"Thyroid stimulating hormone (TSH) signaling pathway; S1P receptor signal transduction; Complement system; G protein signaling pathways; Chemokine signaling pathway; Hippo signaling regulation pathways; Purinergic signaling; Calcium regulation in cardiac cells; 5q35 copy number variation; Serotonin HTR1 group and FOS pathway"	"18"	"0"	"13.4"	"7.7"	"10.2"	"16.3"	"11.6"	"14.9"	"14.6"	"0.0"	"693.5"	"843.2"	"1892.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43581"	"Synaptotagmin-7 OS=Homo sapiens OX=9606 GN=SYT7 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"403"	"45.5"	"9.22"	"281.73"	"3.59"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168"	"9066"	"ENSG00000011347"	"SYT7"	"F5GZC2; F5GZU9; F5H126; F5H1N2; F5H6C1; hsa:9066; O43581; Q08AH6"	"Neurexins and neuroligins"	""	"1"	"0"	"8.6"	"3.1"	"7.3"	"5.4"	"8.6"	"5.5"	"12.4"	"0.0"	"261.0"	"277.0"	"457.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75718"	"Cartilage-associated protein OS=Homo sapiens OX=9606 GN=CRTAP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"401"	"46.5"	"5.73"	"317.96"	"3.59"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	""	""	"10491"	"ENSG00000170275"	"CRTAP"	"B2RBL6; hsa:10491; O75718"	"Collagen biosynthesis and modifying enzymes"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"2"	"0"	"14.6"	"8.3"	"16.4"	"9.2"	"13.9"	"10.2"	"27.4"	"0.1"	"238.7"	"226.2"	"369.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P78346"	"Ribonuclease P protein subunit p30 OS=Homo sapiens OX=9606 GN=RPP30 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"268"	"29.3"	"8.91"	""	"3.58"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01876"	"10556"	"ENSG00000148688"	"RPP30"	"B2R799; E9PB02; hsa:10556; P78346"	"Major pathway of rRNA processing in the nucleolus and cytosol; tRNA processing in the nucleus"	""	"2"	"0"	"4.5"	"5.3"	"7.9"	"4.0"	"7.5"	"6.4"	"13.3"	"1.7"	"91.0"	"112.8"	"249.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54132"	"Bloom syndrome protein OS=Homo sapiens OX=9606 GN=BLM PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"1417"	"158.9"	"7.49"	"441.36"	"3.58"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00570, Pf08072, Pf09382, Pf16124, Pf16202, Pf16204"	"641"	"ENSG00000197299"	"BLM"	"hsa:641; P54132; Q52M96"	"Resolution of D-loop Structures through Holliday Junction Intermediates; SUMOylation of DNA damage response and repair proteins; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Processive synthesis on the C-strand of the telomere"	"Primary ovarian insufficiency"	"18"	"0"	"41.8"	"32.3"	"57.6"	"43.1"	"46.7"	"28.8"	"111.8"	"0.0"	"908.5"	"787.8"	"1679.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPA0"	"ER membrane protein complex subunit 7 OS=Homo sapiens OX=9606 GN=EMC7 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"242"	"26.5"	"9.25"	"424.21"	"3.58"	"1"	"1"	"cell organization and biogenesis"	"other membranes;ER/Golgi"	"other molecular function"	"Pf09430"	"56851"	"ENSG00000134153"	"EMC7"	"B2RC00; hsa:56851; Q96ED5; Q9NPA0"	""	""	"0"	"0"	"13.7"	"7.0"	"14.2"	"13.5"	"11.4"	"12.3"	"33.6"	"6.2"	"237.2"	"239.1"	"498.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNS1"	"Protein timeless homolog OS=Homo sapiens OX=9606 GN=TIMELESS PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1208"	"138.6"	"5.40"	"490.55"	"3.58"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04821, Pf05029"	"8914"	"ENSG00000111602"	"TIMELESS"	"B2ZAV0; hsa:8914; O94802; Q86VM1; Q8IWH3; Q9UNS1"	"Processing of DNA double-strand break ends"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"2.5"	"4.7"	"2.7"	"6.4"	"0.0"	"56.3"	"51.3"	"125.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWY4"	"Histone PARylation factor 1 OS=Homo sapiens OX=9606 GN=HPF1 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"346"	"39.4"	"6.80"	"354.70"	"3.58"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf10228"	"54969"	"ENSG00000056050"	"HPF1"	"hsa:54969; Q9NWY4"	""	""	"0"	"0"	"12.9"	"7.1"	"11.5"	"9.9"	"8.9"	"10.0"	"20.3"	"0.7"	"126.9"	"136.2"	"261.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MN5"	"Transcription elongation factor A N-terminal and central domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TCEANC2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"208"	"24.1"	"10.05"	"353.30"	"3.58"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08711"	"127428"	"ENSG00000116205"	"TCEANC2"	"hsa:127428; Q5T702; Q8N8N2; Q96MN5"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"6.4"	"0.0"	"87.8"	"81.5"	"173.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2E4"	"Disco-interacting protein 2 homolog C OS=Homo sapiens OX=9606 GN=DIP2C PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1556"	"170.7"	"7.39"	"333.93"	"3.58"	"1"	"1"	""	""	""	"Pf00501, Pf06464"	"22982"	"ENSG00000151240"	"DIP2C"	"B4DPI5; hsa:22982; Q5SS78; Q9Y2E4"	""	""	"0"	"0"	"5.1"	"3.2"	"10.1"	"7.7"	"8.2"	"8.8"	"23.1"	"0.0"	"163.3"	"149.3"	"353.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N999"	"Uncharacterized protein C12orf29 OS=Homo sapiens OX=9606 GN=C12orf29 PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"325"	"37.5"	"7.06"	""	"3.57"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	""	"other molecular function"	"Pf17720"	"91298"	"ENSG00000133641"	"RLIG1"	"hsa:91298; Q569K5; Q6AWA8; Q6PEK5; Q8IYQ5; Q8N999; Q9NT75"	""	""	"0"	"0"	"4.5"	"2.2"	"3.5"	"3.5"	"0.0"	"0.0"	"6.2"	"2.9"	"82.7"	"85.0"	"164.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q08426"	"Peroxisomal bifunctional enzyme OS=Homo sapiens OX=9606 GN=EHHADH PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"723"	"79.4"	"9.14"	""	"3.56"	""	"1"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"1962"	"ENSG00000113790"	"EHHADH"	"A8K6Y3; B4DWG3; D3DNU0; hsa:1962; Q08426; Q58EZ5"	"Peroxisomal protein import; Beta-oxidation of very long chain fatty acids"	"Constitutive androstane receptor pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Mitochondrial fatty acid oxidation disorders"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96J01"	"THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"351"	"38.7"	"6.09"	""	"3.56"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08662, Pf12894"	"84321"	"ENSG00000051596"	"THOC3"	"hsa:84321; Q6NZ53; Q96J01"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"66.0"	"43.2"	"48.9"	"56.8"	"59.1"	"42.2"	"99.9"	"0.0"	"396.3"	"328.9"	"860.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TB45"	"DEP domain-containing mTOR-interacting protein OS=Homo sapiens OX=9606 GN=DEPTOR PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"409"	"46.3"	"8.07"	"362.99"	"3.55"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	""	""	"Pf00610"	"64798"	"ENSG00000155792"	"DEPTOR"	"B2RCL9; B4DN97; E7EV87; hsa:64798; Q8TB45; Q96EQ1; Q9H0R7; Q9H894; Q9HA07"	""	"Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Clear cell renal cell carcinoma pathways; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; DYRK1A involvement regarding cell proliferation in brain development"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23511"	"Nuclear transcription factor Y subunit alpha OS=Homo sapiens OX=9606 GN=NFYA PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"347"	"36.9"	"8.94"	"352.05"	"3.54"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02045"	"4800"	"ENSG00000001167"	"NFYA"	"hsa:4800; P23511; Q8IXU0"	"PPARA activates gene expression; Activation of gene expression by SREBF (SREBP); FOXO-mediated transcription of cell death genes; ATF4 activates genes in response to endoplasmic reticulum  stress; ATF6 (ATF6-alpha) activates chaperone genes"	"Sterol regulatory element-binding proteins (SREBP) signaling; Wnt signaling pathway and pluripotency; Sudden infant death syndrome (SIDS) susceptibility pathways"	"8"	"0"	"9.6"	"8.1"	"3.8"	"3.1"	"8.9"	"7.8"	"11.7"	"2.8"	"94.0"	"118.9"	"158.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXW3"	"Progesterone-induced-blocking factor 1 OS=Homo sapiens OX=9606 GN=PIBF1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"757"	"89.8"	"6.02"	"586.24"	"3.54"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding"	""	"10464"	"ENSG00000083535"	"PIBF1"	"hsa:10464; O95664; Q6U9V2; Q6UG50; Q86V07; Q8WXW3; Q96SF4"	""	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies"	"3"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.7"	"0.0"	"13.4"	"0.0"	"151.2"	"131.2"	"226.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15648"	"Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1581"	"168.4"	"8.73"	""	"3.53"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf10744"	"5469"	"ENSG00000125686"	"MED1"	"A2RRQ6; hsa:5469; O43810; O75447; Q15648; Q6P9H7; Q6PK58; Q9HD39"	"Cytoprotection by HMOX1; Estrogen-dependent gene expression; Transcriptional activation of mitochondrial biogenesis; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nuclear Receptor transcription pathway; Activation of gene expression by SREBF (SREBP); RORA activates gene expression"	"Energy metabolism; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; Non-genomic actions of 1,25 dihydroxyvitamin D3; 17q12 copy number variation syndrome"	"17"	"0"	"8.7"	"5.3"	"14.8"	"10.3"	"9.8"	"12.5"	"24.0"	"0.0"	"309.0"	"279.4"	"617.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB7"	"DIS3-like exonuclease 2 OS=Homo sapiens OX=9606 GN=DIS3L2 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"885"	"99.2"	"6.10"	"341.60"	"3.53"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00773, Pf17216, Pf17849, Pf17877"	"129563"	"ENSG00000144535"	"DIS3L2"	"hsa:129563; Q53S79; Q580W6; Q5XKH0; Q69YG5; Q6AW99; Q7Z4T6; Q8IYB7; Q8N9K9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEB9"	"Phosphatidylinositol 3-kinase catalytic subunit type 3 OS=Homo sapiens OX=9606 GN=PIK3C3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"887"	"101.5"	"6.81"	"426.92"	"3.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf00792"	"5289"	"ENSG00000078142"	"PIK3C3"	"hsa:5289; Q15134; Q8NEB9"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the early endosome membrane; Synthesis of PIPs at the late endosome membrane; PI3K Cascade; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Macroautophagy; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex; RHO GTPases Activate NADPH Oxidases; Toll Like Receptor 9 (TLR9) Cascade"	"AMP-activated protein kinase signaling; Alzheimer's disease and miRNA effects; Angiopoietin-like protein 8 regulatory pathway; Microglia pathogen phagocytosis pathway; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Osteoblast differentiation and related diseases; Insulin signaling; Autophagy; Regulation of actin cytoskeleton; Alzheimer's disease; Clock-controlled autophagy in bone metabolism; DNA damage response (only ATM dependent)"	"23"	"0"	"11.6"	"9.7"	"14.4"	"12.5"	"16.3"	"13.8"	"15.9"	"2.5"	"137.9"	"143.7"	"270.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2K1"	"Zinc finger and BTB domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ZBTB1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"713"	"82.0"	"6.39"	"410.91"	"3.52"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00651"	"22890"	"ENSG00000126804"	"ZBTB1"	"A8K6S8; hsa:22890; Q86SW8; Q9Y2K1"	""	""	"0"	"0"	"7.1"	"3.4"	"4.7"	"5.4"	"2.4"	"0.0"	"10.5"	"0.0"	"49.4"	"98.7"	"64.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00193"	"Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1"	"0.000"	""	"13"	"2"	"3"	"2"	"183"	"20.3"	"4.72"	"824.65"	"3.52"	"2"	"1"	""	""	""	"Pf15477"	"10944"	"ENSG00000110696"	"SMAP"	"B2RD28; hsa:10944; O00193"	""	""	"0"	"0"	"363.8"	"286.5"	"333.6"	"347.3"	"288.2"	"297.8"	"457.5"	"0.8"	"686.8"	"690.0"	"1031.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UN81"	"LINE-1 retrotransposable element ORF1 protein OS=Homo sapiens OX=9606 GN=L1RE1 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"338"	"40.0"	"9.51"	""	"3.51"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02994, Pf17489, Pf17490"	""	""	"L1RE1"	"Q15605; Q9UN81"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00966"	"Argininosuccinate synthase OS=Homo sapiens OX=9606 GN=ASS1 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"412"	"46.5"	"8.02"	"417.74"	"3.50"	"1"	"1"	"other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00764"	"445"	"ENSG00000130707"	"ASS1"	"hsa:445; P00966; Q6LDL2; Q86UZ0; Q96GT4"	"Urea cycle"	"Alanine and aspartate metabolism; Amino acid metabolism"	"3"	"0"	"4.3"	"3.9"	"0.0"	"3.1"	"4.7"	"2.0"	"11.9"	"2.5"	"73.2"	"76.7"	"143.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5NDL2"	"EGF domain-specific O-linked N-acetylglucosamine transferase OS=Homo sapiens OX=9606 GN=EOGT PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"527"	"62.0"	"7.05"	"332.77"	"3.50"	"1"	"1"	"protein metabolism;other metabolic processes"	"ER/Golgi"	"other molecular function"	"Pf04577"	"285203"	"ENSG00000163378"	"EOGT"	"A8K2U1; B4DFH5; hsa:285203; L7X1M5; Q5NDL2; Q6MZY0; Q6P985; Q6ZTV0"	""	"Genetic causes of porto-sinusoidal vascular disease"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0E2"	"Toll-interacting protein OS=Homo sapiens OX=9606 GN=TOLLIP PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"274"	"30.3"	"5.97"	"255.70"	"3.50"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf02845"	"54472"	"ENSG00000078902"	"TOLLIP"	"B3KXC6; hsa:54472; Q9H0E2; Q9H9E6; Q9UJ69"	"Neutrophil degranulation; Interleukin-1 signaling"	"IL-1 signaling pathway; Interleukin-1 (IL-1) structural pathway; Toll-like receptor signaling related to MyD88; Signal transduction through IL1R; Toll-like receptor signaling pathway"	"7"	"0"	"8.8"	"9.3"	"8.8"	"10.0"	"11.7"	"12.1"	"11.3"	"1.3"	"112.1"	"127.0"	"300.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NYB9"	"Abl interactor 2 OS=Homo sapiens OX=9606 GN=ABI2 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"513"	"55.6"	"6.16"	""	"3.50"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07815, Pf14604"	"10152"	"ENSG00000138443"	"ABI2"	"B4DSN1; hsa:10152; Q13147; Q13249; Q13801; Q9BV70; Q9NYB9"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"Regulation of actin cytoskeleton"	"8"	"0"	"45.8"	"35.4"	"45.0"	"44.6"	"38.9"	"45.3"	"117.0"	"0.0"	"439.9"	"433.3"	"1000.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EH3"	"Mitochondrial assembly of ribosomal large subunit protein 1 OS=Homo sapiens OX=9606 GN=MALSU1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"234"	"26.2"	"5.49"	"426.86"	"3.49"	"1"	"1"	"other biological processes"	"cytosol;mitochondrion"	"translation activity"	"Pf02410"	"115416"	"ENSG00000156928"	"MALSU1"	"A4D154; hsa:115416; Q96EH3"	""	""	"0"	"0"	"0.0"	"3.2"	"0.0"	"4.3"	"3.6"	"0.0"	"6.5"	"0.0"	"161.0"	"160.4"	"363.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRJ7"	"Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"211"	"23.3"	"8.91"	"368.84"	"3.49"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	""	"84309"	"ENSG00000168101"	"NUDT16L1"	"hsa:84309; Q8NAI2; Q9BRJ7"	""	""	"0"	"0"	"4.1"	"0.0"	"3.6"	"3.6"	"0.0"	"2.5"	"9.2"	"1.3"	"53.0"	"52.2"	"99.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBZ3"	"WD repeat-containing protein 20 OS=Homo sapiens OX=9606 GN=WDR20 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"569"	"62.9"	"8.00"	"399.23"	"3.49"	"1"	"1"	""	"nucleus"	""	"Pf00400"	"91833"	"ENSG00000140153"	"WDR20"	"B4DN18; E7EUY8; F8W9S4; G3V2F8; G3V5R0; H0YJJ1; hsa:91833; Q86TU2; Q8NCN7; Q8TBZ3; Q8WXX2; Q9UF86"	"Ub-specific processing proteases"	""	"1"	"0"	"3.9"	"4.5"	"7.2"	"6.4"	"7.9"	"5.1"	"15.9"	"4.2"	"90.1"	"99.6"	"190.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969R5"	"Lethal(3)malignant brain tumor-like protein 2 OS=Homo sapiens OX=9606 GN=L3MBTL2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"705"	"79.1"	"6.84"	"321.67"	"3.49"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus"	"other molecular function"	"Pf02820"	"83746"	"ENSG00000100395"	"L3MBTL2"	"hsa:83746; Q8TEN1; Q969R5; Q96SC4; Q9BQI2; Q9UGS4"	"SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6"	""	"2"	"0"	"14.6"	"12.4"	"19.6"	"21.8"	"13.6"	"13.5"	"29.5"	"0.0"	"269.3"	"265.0"	"656.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AT1"	"Uncharacterized protein KIAA1143 OS=Homo sapiens OX=9606 GN=KIAA1143 PE=1 SV=2"	"0.000"	""	"18"	"2"	"3"	"2"	"154"	"17.5"	"6.11"	"950.66"	"3.49"	"2"	"1"	""	""	""	"Pf15377"	"57456"	"ENSG00000163807; ENSG00000281665"	"KIAA1143"	"A8K0I4; hsa:57456; Q96AT1; Q96HJ8; Q9ULS7"	""	""	"0"	"0"	"29.5"	"22.9"	"28.4"	"24.6"	"26.4"	"25.7"	"53.6"	"1.1"	"650.5"	"609.1"	"1532.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0B0"	"RING finger protein unkempt homolog OS=Homo sapiens OX=9606 GN=UNK PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"810"	"88.0"	"6.86"	"336.88"	"3.48"	"1"	"1"	"developmental processes;other biological processes"	"other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf18384"	"85451"	"ENSG00000132478"	"UNK"	"hsa:85451; Q9C0B0"	""	""	"0"	"0"	"11.7"	"14.7"	"14.7"	"13.9"	"14.6"	"13.9"	"26.4"	"1.8"	"70.4"	"68.4"	"137.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N5I2"	"Arrestin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARRDC1 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"433"	"46.0"	"7.02"	""	"3.48"	""	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00339, Pf02752"	"92714"	"ENSG00000197070"	"ARRDC1"	"hsa:92714; Q8N5I2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7LBR1"	"Charged multivesicular body protein 1b OS=Homo sapiens OX=9606 GN=CHMP1B PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"199"	"22.1"	"8.10"	""	"3.48"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"57132"	"ENSG00000255112"	"CHMP1B"	"hsa:57132; Q7LBR1; Q96E89; Q9HD41"	""	""	"0"	"0"	"7.2"	"4.5"	"8.1"	"7.2"	"5.9"	"6.8"	"15.5"	"0.0"	"550.3"	"550.1"	"1344.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43003"	"Excitatory amino acid transporter 1 OS=Homo sapiens OX=9606 GN=SLC1A3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"542"	"59.5"	"8.41"	"421.43"	"3.48"	"1"	"1"	"cell-cell signaling;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00375"	"6507"	"ENSG00000079215"	"SLC1A3"	"B2R5T3; hsa:6507; P43003; Q4JCQ8"	"Glutamate Neurotransmitter Release Cycle; Transport of inorganic cations/anions and amino acids/oligopeptides; Astrocytic Glutamate-Glutamine Uptake And Metabolism; Defective SLC1A3 causes episodic ataxia 6 (EA6)"	"Synaptic vesicle pathway; Neuroinflammation and glutamatergic signaling; Sudden infant death syndrome (SIDS) susceptibility pathways"	"7"	"0"	"10.5"	"6.0"	"13.1"	"9.7"	"10.5"	"7.5"	"14.3"	"1.2"	"212.0"	"215.5"	"463.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96B36"	"Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"256"	"27.4"	"4.75"	"284.94"	"3.47"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15798"	"84335"	"ENSG00000204673"	"AKT1S1"	"A8MTQ1; B2RE93; hsa:84335; J3KPM3; Q96B36; Q96BI4; Q96IK7; Q96NG2; Q9BWR5"	"Constitutive Signaling by AKT1 E17K in Cancer; AKT phosphorylates targets in the cytosol; mTORC1-mediated signalling; HSF1-dependent transactivation"	"Target of rapamycin signaling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; Thermogenesis; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Thyroid hormones production and peripheral downstream signaling effects; Autophagy; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells"	"21"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N8S7"	"Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2"	"0.000"	""	"5"	"2"	"5"	"2"	"591"	"66.5"	"6.93"	"1188.15"	"3.47"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"55740"	"ENSG00000154380"	"ENAH"	"D0PQI2; hsa:55740; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q8N8S7; Q9NVF3; Q9UFB8"	"Generation of second messenger molecules; Signaling by ROBO receptors"	"Regulation of actin cytoskeleton"	"3"	"0"	"49.3"	"50.0"	"60.4"	"59.2"	"50.8"	"61.1"	"170.1"	"3.3"	"537.6"	"535.5"	"1163.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RY7"	"Intraflagellar transport protein 140 homolog OS=Homo sapiens OX=9606 GN=IFT140 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1462"	"165.1"	"6.04"	"357.74"	"3.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytoskeleton;other cell component"	""	""	"9742"	"ENSG00000187535"	"IFT140"	"A2A2A8; D3DU75; hsa:9742; O60332; Q96RY7; Q9UG52"	"Intraflagellar transport; Hedgehog 'off' state"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"7"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.8"	"0.0"	"4.7"	"0.0"	"27.7"	"32.5"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13685"	"Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"434"	"46.7"	"4.42"	""	"3.47"	""	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00400"	"14"	"ENSG00000127837"	"AAMP"	"hsa:14; Q13685; Q8WUJ9; Q96H92"	"NOD1/2 Signaling Pathway; Thromboxane signalling through TP receptor; Signaling by EGFR; Signaling by VEGF"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"5"	"0"	"4.4"	"2.8"	"4.8"	"3.9"	"4.9"	"0.0"	"8.3"	"0.0"	"29.5"	"30.3"	"68.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9HC56"	"Protocadherin-9 OS=Homo sapiens OX=9606 GN=PCDH9 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1237"	"136.0"	"5.47"	""	"3.46"	""	"1"	"cell adhesion"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028, Pf08266, Pf08374"	"5101"	"ENSG00000184226"	"PCDH9"	"A2A6U1; hsa:5101; Q5VT83; Q7Z3U0; Q8N3K7; Q9HC56"	""	""	"0"	"0"	"5.0"	"4.2"	"2.0"	"2.5"	"2.1"	"4.7"	"6.6"	"2.5"	"56.0"	"62.3"	"115.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWB7"	"Intraflagellar transport protein 57 homolog OS=Homo sapiens OX=9606 GN=IFT57 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"429"	"49.1"	"4.98"	"384.62"	"3.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf10498"	"55081"	"ENSG00000114446"	"IFT57"	"hsa:55081; Q96DA9; Q9NWB7"	"Intraflagellar transport; Hedgehog 'off' state"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P11717"	"Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3"	""	""	"0"	"1"	"1"	"1"	"2491"	"274.2"	"5.94"	""	"3.46"	""	"1"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00040, Pf00878"	"3482"	"ENSG00000197081"	"IGF2R"	"hsa:3482; P11717; Q7Z7G9; Q96PT5"	"Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; Retrograde transport at the Trans-Golgi-Network"	"TROP2 regulatory signaling"	"6"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.7"	"1.5"	"52.4"	"58.6"	"177.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43159"	"Ribosomal RNA-processing protein 8 OS=Homo sapiens OX=9606 GN=RRP8 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"456"	"50.7"	"9.42"	"318.18"	"3.46"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf05148"	"23378"	"ENSG00000132275"	"RRP8"	"hsa:23378; O43159; Q7KZ78; Q9BVM6"	"SIRT1 negatively regulates rRNA expression"	""	"1"	"0"	"2.8"	"0.0"	"2.8"	"0.0"	"2.8"	"4.9"	"6.9"	"0.0"	"64.5"	"66.9"	"82.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYR9"	"NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"191"	"21.5"	"8.05"	"383.63"	"3.46"	"1"	"1"	"stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00071"	"28511"	"ENSG00000168256"	"NKIRAS2"	"A6NCZ5; B3KNN0; B4DNM3; hsa:28511; Q6PK52; Q96KC7; Q9NSX1; Q9NYR9"	"RIP-mediated NFkB activation via ZBP1; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation"	""	"3"	"0"	"6.3"	"4.0"	"4.0"	"3.9"	"5.4"	"7.9"	"24.1"	"3.4"	"197.6"	"207.2"	"449.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7Z745"	"Maestro heat-like repeat-containing protein family member 2B OS=Homo sapiens OX=9606 GN=MROH2B PE=2 SV=3"	""	""	"1"	"1"	"1"	"1"	"1585"	"180.7"	"6.28"	""	"3.45"	""	"1"	"signal transduction;other biological processes"	"cytoskeleton;other cell component"	""	""	"133558"	"ENSG00000171495"	"MROH2B"	"hsa:133558; Q68DM1; Q7Z4U4; Q7Z745; Q8N7X3"	""	""	"0"	"0"	"195.2"	"134.3"	"163.5"	"152.7"	"159.2"	"144.2"	"273.7"	"0.5"	"595.0"	"590.1"	"1115.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QE3"	"ATPase family AAA domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ATAD5 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1844"	"207.4"	"9.19"	"310.10"	"3.45"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004"	"79915"	"ENSG00000176208"	"ATAD5"	"hsa:79915; Q05DH0; Q69YR6; Q96QE3; Q9H9I1"	""	""	"0"	"0"	"4.6"	"3.5"	"4.2"	"5.9"	"6.1"	"2.6"	"12.0"	"0.0"	"103.1"	"103.3"	"204.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6F5"	"Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"360"	"40.2"	"10.33"	"493.06"	"3.45"	"1"	"1"	""	"nucleus;other cell component"	""	"Pf03879"	"79080"	"ENSG00000110104"	"CCDC86"	"B4DY99; hsa:79080; Q9H6F5"	""	""	"0"	"0"	"7.8"	"3.8"	"4.7"	"4.6"	"4.8"	"2.8"	"11.8"	"2.2"	"31.5"	"25.3"	"56.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y5V0"	"Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"76"	"8.5"	"10.01"	""	"3.45"	""	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04419, Pf12874"	"51123"	"ENSG00000120963"	"ZNF706"	"A8K362; hsa:51123; Q9Y5V0"	"Generic Transcription Pathway"	""	"1"	"0"	"26.9"	"33.4"	"29.4"	"31.1"	"31.7"	"18.6"	"80.7"	"0.0"	"473.9"	"527.7"	"786.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HA1"	"Nuclear envelope pore membrane protein POM 121 OS=Homo sapiens OX=9606 GN=POM121 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1249"	"127.6"	"10.56"	"654.67"	"3.44"	"2"	"1"	"transport"	"other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf15229"	"9883"	"ENSG00000196313"	"POM121"	"A6NFS9; A8CDT4; A8K933; A8MXF9; hsa:9883; O75115; Q96DI0; Q96HA1; Q9H9X1; Q9Y2N3; Q9Y4S7"	"HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"Ciliary landscape"	"30"	"0"	"37.7"	"26.9"	"45.6"	"45.9"	"28.2"	"39.9"	"82.3"	"0.0"	"398.0"	"397.4"	"649.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33316"	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4"	"0.000"	""	"8"	"2"	"2"	"2"	"252"	"26.5"	"9.36"	"261.49"	"3.44"	"1"	"1"	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00692"	"1854"	"ENSG00000128951"	"DUT"	"A8K650; B4DPR5; hsa:1854; O14785; P33316; Q16708; Q16860; Q6FHN1; Q6NSA3; Q96Q81"	""	"Pyrimidine metabolism"	"1"	"0"	"89.3"	"71.0"	"86.5"	"96.2"	"87.9"	"74.6"	"151.9"	"0.0"	"1079.0"	"1165.9"	"2614.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4W2"	"Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"734"	"83.0"	"4.73"	"302.47"	"3.43"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04031"	"81887"	"ENSG00000001497"	"LAS1L"	"A9X410; hsa:81887; Q5JXQ0; Q8TEN5; Q9H9V5; Q9Y4W2"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"6.7"	"9.5"	"9.3"	"10.9"	"10.7"	"1.7"	"22.9"	"1.0"	"124.4"	"155.0"	"234.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y248"	"DNA replication complex GINS protein PSF2 OS=Homo sapiens OX=9606 GN=GINS2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"185"	"21.4"	"5.44"	"288.99"	"3.43"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf05916"	"51659"	"ENSG00000131153"	"GINS2"	"D3DUM5; hsa:51659; Q6IAG9; Q9Y248"	"Unwinding of DNA"	""	"1"	"0"	"11.3"	"6.4"	"17.0"	"15.4"	"14.2"	"15.6"	"36.1"	"0.6"	"129.1"	"121.8"	"232.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5B6"	"PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"917"	"104.7"	"5.68"	"301.50"	"3.43"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf07842"	"94104"	"ENSG00000159086; ENSG00000263141"	"PAXBP1"	"D3DSE7; hsa:94104; Q96DU8; Q9NYQ0; Q9Y5B6"	""	""	"0"	"0"	"10.4"	"7.3"	"10.4"	"7.1"	"12.3"	"7.1"	"13.8"	"3.5"	"131.6"	"135.8"	"304.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05823"	"2-5A-dependent ribonuclease OS=Homo sapiens OX=9606 GN=RNASEL PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"741"	"83.5"	"6.65"	"421.93"	"3.43"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00023, Pf00069, Pf06479"	"6041"	"ENSG00000135828"	"RNASEL"	"hsa:6041; Q05823; Q5W0L2; Q6AI46"	"OAS antiviral response; Interferon alpha/beta signaling"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ7"	"Serine/Arginine-related protein 53 OS=Homo sapiens OX=9606 GN=RSRC1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"334"	"38.7"	"11.08"	"329.75"	"3.43"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	""	""	"51319"	"ENSG00000174891"	"RSRC1"	"A8K2R9; hsa:51319; Q96IZ7; Q96QK2; Q9NZE5"	""	""	"0"	"0"	"8.1"	"6.3"	"8.6"	"6.8"	"6.1"	"6.9"	"10.7"	"1.3"	"52.6"	"49.8"	"111.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75880"	"Protein SCO1 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=SCO1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"301"	"33.8"	"8.88"	"400.40"	"3.42"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytoskeleton;mitochondrion"	"other molecular function"	"Pf02630"	"6341"	"ENSG00000133028"	"SCO1"	"B2RDM0; hsa:6341; O75880"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Copper homeostasis"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WR7"	"Proline and serine-rich protein 2 OS=Homo sapiens OX=9606 GN=PROSER2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"435"	"45.8"	"7.20"	"396.11"	"3.42"	"1"	"1"	""	""	""	"Pf15385"	"254427"	"ENSG00000148426"	"PROSER2"	"D3DRR8; hsa:254427; Q5W0J9; Q5W0K0; Q5W0K1; Q5W0K2; Q6PJC8; Q86WR7; Q8N317"	""	""	"0"	"0"	"4.5"	"3.0"	"3.1"	"4.1"	"4.4"	"0.0"	"20.0"	"0.0"	"40.3"	"40.6"	"59.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVK2"	"U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP27 PE=1 SV=1"	"0.000"	""	"14"	"2"	"3"	"2"	"155"	"18.8"	"11.62"	"493.70"	"3.42"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf08648"	"11017"	"ENSG00000124380"	"SNRNP27"	"hsa:11017; Q15410; Q8WVK2"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"62.2"	"43.9"	"49.8"	"54.6"	"57.7"	"52.3"	"141.4"	"8.6"	"1125.1"	"1138.7"	"2120.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82930"	"28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"218"	"25.6"	"9.98"	"302.43"	"3.42"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf16053"	"65993"	"ENSG00000074071"	"MRPS34"	"hsa:65993; P82930; Q9BVI7"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"50.1"	"50.3"	"74.3"	"55.1"	"56.5"	"59.5"	"121.4"	"0.0"	"405.1"	"408.4"	"705.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWZ8"	"SURP and G-patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUGP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"645"	"72.4"	"7.61"	"313.00"	"3.41"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"57794"	"ENSG00000105705"	"SUGP1"	"hsa:57794; O60378; Q6P3X9; Q8IWZ8; Q8TCQ4; Q8WWT4; Q8WWT5; Q9NTG3"	"mRNA Splicing - Major Pathway"	"mRNA processing"	"2"	"0"	"37.8"	"24.3"	"44.1"	"44.6"	"35.8"	"43.4"	"105.5"	"7.6"	"371.7"	"344.1"	"740.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VWG9"	"Transcription initiation factor TFIID subunit 3 OS=Homo sapiens OX=9606 GN=TAF3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"929"	"103.5"	"9.06"	"305.77"	"3.41"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus"	"other molecular function"	"Pf00628, Pf07524"	"83860"	"ENSG00000165632"	"TAF3"	"hsa:83860; Q05DA0; Q5VWG9; Q6GMS5; Q6P6B5; Q86VY6; Q9BQS9; Q9UFI8"	"Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	""	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NJ78"	"12S rRNA N4-methylcytidine (m4C) methyltransferase OS=Homo sapiens OX=9606 GN=METTL15 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"407"	"46.1"	"8.62"	"256.43"	"3.41"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01795"	"196074"	"ENSG00000169519"	"METTL15"	"A6NJ78; A8MRS5; B7WNU2; hsa:196074; Q3MHD3; Q8N601; Q8NBA7"	""	""	"0"	"0"	"56.5"	"42.5"	"54.1"	"51.7"	"48.7"	"59.5"	"103.5"	"0.0"	"772.0"	"708.3"	"1371.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UIL1"	"Short coiled-coil protein OS=Homo sapiens OX=9606 GN=SCOC PE=1 SV=2"	""	""	"14"	"1"	"1"	"1"	"159"	"18.0"	"8.85"	""	"3.41"	""	"1"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf10224"	"60592"	"ENSG00000153130"	"SCOC"	"B7WPH7; D3DNY7; E9PB65; hsa:60592; Q6P5T9; Q7L2Y0; Q7Z4P2; Q96JY9; Q9BZB2; Q9UIL1"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A1XBS5"	"Protein FAM92A OS=Homo sapiens OX=9606 GN=FAM92A PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"289"	"33.4"	"6.21"	"335.91"	"3.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf06730"	"137392"	"ENSG00000188343"	"CIBAR1"	"A1XBS4; A1XBS5; hsa:137392; Q32ND3; Q6AHW7; Q8N8R1; Q96L09"	""	"Genes related to primary cilium development (based on CRISPR)"	"1"	"0"	"2.9"	"0.0"	"2.1"	"0.0"	"0.0"	"3.4"	"7.0"	"0.0"	"87.1"	"67.9"	"154.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCJ2"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"826"	"93.6"	"8.91"	"244.16"	"3.40"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf02516"	"201595"	"ENSG00000163527"	"STT3B"	"hsa:201595; Q8TCJ2; Q96JZ4; Q96KY7"	""	"N-glycan biosynthesis"	"1"	"0"	"43.2"	"35.8"	"56.5"	"46.0"	"38.3"	"51.1"	"87.2"	"5.6"	"407.0"	"445.8"	"990.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUG6"	"p53 and DNA damage-regulated protein 1 OS=Homo sapiens OX=9606 GN=PDRG1 PE=1 SV=2"	"0.000"	""	"10"	"1"	"2"	"1"	"133"	"15.5"	"6.06"	"325.78"	"3.40"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"81572"	"ENSG00000088356"	"PDRG1"	"B2R511; hsa:81572; Q96GP3; Q9BUW8; Q9NUG6"	""	""	"0"	"0"	"11.8"	"6.5"	"13.2"	"9.3"	"15.5"	"14.1"	"29.0"	"2.8"	"224.1"	"233.2"	"486.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15057"	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ACAP2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"778"	"88.0"	"6.80"	"274.39"	"3.40"	"1"	"1"	"transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412, Pf12796, Pf16746"	"23527"	"ENSG00000114331"	"ACAP2"	"A8K2V4; hsa:23527; Q15057; Q8N5Z8; Q9UQR3"	""	""	"0"	"0"	"18.1"	"11.6"	"24.5"	"19.3"	"17.6"	"15.5"	"26.3"	"0.0"	"242.5"	"244.7"	"501.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11413"	"Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4"	"0.000"	""	"6"	"2"	"3"	"2"	"515"	"59.2"	"6.84"	"965.64"	"3.40"	"2"	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00479, Pf02781"	"2539"	"ENSG00000160211"	"G6PD"	"D3DWX9; hsa:2539; P11413; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2"	"TP53 Regulates Metabolic Genes; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"Glutathione metabolism; Pentose phosphate metabolism; Cori cycle; Vitamin D receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; ATM signaling in development and disease ; Metabolic reprogramming in colon cancer; Vitamin D-sensitive calcium signaling in depression; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sulfation biotransformation reaction"	"16"	"0"	"71.5"	"54.2"	"61.5"	"60.4"	"58.1"	"68.5"	"111.7"	"7.8"	"761.0"	"721.7"	"1686.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62195"	"26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"406"	"45.6"	"7.55"	"374.87"	"3.39"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf16450, Pf17862"	"5705"	"ENSG00000087191"	"PSMC5"	"A8K3Z3; A8K763; hsa:5705; O35051; O43208; P47210; P52915; P52916; P62195"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Alzheimer's disease"	"65"	"0"	"12.1"	"7.6"	"13.4"	"9.3"	"8.9"	"9.7"	"17.3"	"0.0"	"240.6"	"217.3"	"611.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L91"	"E1A-binding protein p400 OS=Homo sapiens OX=9606 GN=EP400 PE=1 SV=4"	"0.000"	""	"0"	"1"	"2"	"1"	"3159"	"343.3"	"9.19"	"384.62"	"3.38"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf07529, Pf15790"	"57634"	"ENSG00000183495"	"EP400"	"hsa:57634; O15411; Q6P2F5; Q8N8Q7; Q8NE05; Q96JK7; Q96L91; Q9P230"	"HATs acetylate histones; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95793"	"Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"577"	"63.1"	"9.44"	"366.62"	"3.38"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf16482"	"6780"	"ENSG00000124214"	"STAU1"	"A8K9Z4; E1P5Y1; E1P608; hsa:6780; O95793; Q5JW29; Q6GTM4; Q9H5B4; Q9H5B5; Q9Y3Q2"	""	""	"0"	"0"	"23.1"	"7.8"	"25.0"	"22.1"	"23.8"	"17.4"	"24.3"	"2.2"	"110.5"	"79.8"	"182.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00492"	"Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"218"	"24.6"	"6.68"	"314.04"	"3.38"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00156"	"3251"	"ENSG00000165704"	"HPRT1"	"A6NHF0; B2R8M9; hsa:3251; P00492"	"Azathioprine ADME; Purine salvage; Defective HPRT1 disrupts guanine and hypoxanthine salvage"	"Mesodermal commitment pathway"	"4"	"0"	"10.8"	"11.0"	"18.1"	"12.2"	"12.4"	"12.2"	"18.2"	"0.0"	"79.5"	"80.2"	"163.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1B4"	"Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"723"	"82.2"	"5.99"	"322.31"	"3.37"	"1"	"1"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04129"	"6293"	"ENSG00000206286; ENSG00000223501; ENSG00000224455; ENSG00000225590; ENSG00000228425; ENSG00000236014"	"VPS52"	"A2BF38; B0UZZ4; B4DNI9; hsa:6293; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q8N1B4; Q9NPT5"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	"4.1"	"5.9"	"5.5"	"6.1"	"6.4"	"9.1"	"15.8"	"0.0"	"119.2"	"99.1"	"202.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15853"	"Upstream stimulatory factor 2 OS=Homo sapiens OX=9606 GN=USF2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"346"	"36.9"	"5.10"	"278.15"	"3.37"	"1"	"1"	"transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7392"	"ENSG00000105698"	"USF2"	"hsa:7392; O00671; O00709; Q05750; Q07952; Q15851; Q15852; Q15853; Q6FI33; Q6YI47"	"Estrogen-dependent gene expression"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)"	"2"	"0"	"32.0"	"18.7"	"23.2"	"27.8"	"30.8"	"13.1"	"42.6"	"0.0"	"233.3"	"203.3"	"500.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NFD5"	"AT-rich interactive domain-containing protein 1B OS=Homo sapiens OX=9606 GN=ARID1B PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"2236"	"236.0"	"6.73"	""	"3.37"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"12.3"	"10.9"	"16.6"	"15.4"	"25.0"	"18.3"	"42.6"	"0.0"	"133.6"	"128.0"	"233.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14727"	"Apoptotic protease-activating factor 1 OS=Homo sapiens OX=9606 GN=APAF1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"3"	"1"	"1248"	"141.7"	"6.40"	"670.81"	"3.36"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400, Pf00619, Pf00931, Pf17908"	"317"	"ENSG00000120868"	"APAF1"	"B2RMX8; hsa:317; O14727; O43297; Q7Z438; Q9BXZ6; Q9UBZ5; Q9UGN8; Q9UGN9; Q9UGP0; Q9UJ58; Q9UJ59; Q9UJ60; Q9UJ61; Q9UJ62; Q9UJ63; Q9UJ64; Q9UJ65; Q9UJ66; Q9UJ67; Q9UNC9"	"Neutrophil degranulation; Transcriptional Regulation by E2F6; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of the apoptosome activity"	"miRNA regulation of DNA damage response; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkinson's disease pathway; Amyotrophic lateral sclerosis (ALS); Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; Oxidative damage response; miRNA regulation of p53 pathway in prostate cancer; Measles virus infection; Small cell lung cancer; Hepatitis B infection; Regucalcin in proximal tubule epithelial kidney cells; Host-pathogen interaction of human coronaviruses - apoptosis; p53 transcriptional gene network; Complement system in neuronal development and plasticity; Alzheimer's disease; CKAP4 signaling pathway map; DNA damage response"	"29"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.5"	"1.8"	"52.2"	"48.7"	"101.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZQ3"	"NCK-interacting protein with SH3 domain OS=Homo sapiens OX=9606 GN=NCKIPSD PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"722"	"78.9"	"6.38"	"324.78"	"3.36"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf09431"	"51517"	"ENSG00000213672"	"NCKIPSD"	"B4DFL5; hsa:51517; Q6GU34; Q6SPF3; Q8TC10; Q9NZQ3; Q9UGM8"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTZ6"	"RNA-binding protein 12 OS=Homo sapiens OX=9606 GN=RBM12 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"932"	"97.3"	"8.63"	"259.69"	"3.36"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"10137"	"ENSG00000244462"	"RBM12"	"B3KRU2; E1P5R6; hsa:10137; O94865; Q8N3B1; Q9H196; Q9NTZ6"	""	""	"0"	"0"	"16.4"	"9.4"	"20.5"	"12.9"	"18.4"	"15.4"	"28.3"	"0.0"	"175.1"	"206.1"	"412.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14CB8"	"Rho GTPase-activating protein 19 OS=Homo sapiens OX=9606 GN=ARHGAP19 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"494"	"55.7"	"9.36"	"361.81"	"3.36"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf00620"	"84986"	"ENSG00000213390"	"ARHGAP19"	"A1XCP1; B4DZR1; hsa:84986; Q14CB8; Q14CF2; Q5J8M2; Q5T460; Q5T462; Q68DG6; Q8N9X1; Q8NF34; Q8TEK1"	"RHOA GTPase cycle"	""	"1"	"0"	"0.0"	"0.0"	"2.5"	"0.0"	"2.0"	"0.0"	"4.5"	"1.6"	"38.5"	"38.8"	"134.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P19022"	"Cadherin-2 OS=Homo sapiens OX=9606 GN=CDH2 PE=1 SV=4"	""	""	"3"	"1"	"1"	"1"	"906"	"99.7"	"4.81"	""	"3.35"	""	"1"	"cell adhesion;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00028, Pf01049, Pf08758"	"1000"	"ENSG00000170558"	"CDH2"	"A8MWK3; B0YIY6; hsa:1000; P19022; Q14923; Q8N173"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Myogenesis; Adherens junctions interactions"	"Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Splicing factor NOVA regulated synaptic proteins; Epithelial to mesenchymal transition in colorectal cancer; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling"	"16"	"0"	"2.5"	"3.9"	"3.2"	"0.0"	"1.9"	"0.0"	"4.0"	"0.0"	"15.2"	"23.5"	"59.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q06265"	"Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"439"	"48.9"	"5.29"	""	"3.35"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"5393"	"ENSG00000123737"	"EXOSC9"	"hsa:5393; Q06265; Q12883; Q4W5P5; Q86Y41; Q86Y48"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"Ciliary landscape"	"7"	"0"	"0.0"	"2.1"	"5.1"	"2.2"	"4.7"	"0.0"	"17.0"	"2.7"	"145.1"	"132.3"	"405.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15276"	"Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"862"	"99.2"	"5.01"	"274.96"	"3.35"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf03528, Pf09311"	"9135"	"ENSG00000029725"	"RABEP1"	"B2RAG7; hsa:9135; O95369; Q15276; Q8IVX3"	"TBC/RABGAPs"	"GDNF signaling"	"2"	"0"	"18.1"	"8.3"	"26.6"	"11.4"	"17.1"	"17.9"	"35.3"	"1.5"	"170.5"	"171.9"	"422.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61970"	"Nuclear transport factor 2 OS=Homo sapiens OX=9606 GN=NUTF2 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"127"	"14.5"	"5.38"	"358.85"	"3.34"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02136"	"10204"	"ENSG00000102898"	"NUTF2"	"B2R4G7; hsa:10204; P13662; P61970; Q6IB67"	""	""	"0"	"0"	"4.9"	"5.2"	"8.7"	"6.1"	"7.4"	"4.2"	"8.3"	"0.3"	"59.4"	"67.4"	"155.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX18"	"Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"779"	"88.5"	"8.65"	"409.31"	"3.34"	"1"	"1"	""	""	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"79665"	"ENSG00000108406"	"DHX40"	"B3KTJ5; C9JR60; hsa:79665; Q5JPH4; Q8IX18; Q8TC86; Q8WY53; Q9BXM1; Q9H6M9"	""	""	"0"	"0"	"10.4"	"10.6"	"14.3"	"13.7"	"17.8"	"13.5"	"23.8"	"2.0"	"396.2"	"406.7"	"834.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60900"	"Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"246"	"27.4"	"6.76"	""	"3.34"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5687"	"ENSG00000100902"	"PSMA6"	"B2R7J9; B4DQR4; B4DXJ9; hsa:5687; P34062; P60900; Q6IB60"	"Separation of Sister Chromatids; Downstream TCR signaling; FCERI mediated NF-kB activation; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"10.1"	"7.1"	"11.0"	"13.2"	"10.0"	"7.2"	"19.6"	"0.0"	"116.0"	"124.2"	"280.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N2Z9"	"Centromere protein S OS=Homo sapiens OX=9606 GN=CENPS PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"138"	"15.9"	"6.05"	"402.24"	"3.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15630"	"100526739; 378708"	"ENSG00000175279"	"CENPS"	"hsa:100526739; hsa:378708; Q8N2Z9; Q8NFE5; Q8NFG5"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Fanconi Anemia Pathway; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Deposition of new CENPA-containing nucleosomes at the centromere; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"DNA repair pathways, full network"	"9"	"0"	"8.0"	"6.2"	"12.8"	"6.5"	"9.1"	"8.5"	"15.0"	"0.0"	"231.4"	"223.9"	"516.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NC60"	"Nitric oxide-associated protein 1 OS=Homo sapiens OX=9606 GN=NOA1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"698"	"78.4"	"8.66"	""	"3.33"	""	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf01926"	"84273"	"ENSG00000084092"	"NOA1"	"hsa:84273; Q8N7L6; Q8NC60; Q9BSQ9"	""	""	"0"	"0"	"5.9"	"2.7"	"5.2"	"5.7"	"6.2"	"8.6"	"25.9"	"1.8"	"106.0"	"83.7"	"201.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y4K4"	"Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP4K5 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"846"	"95.0"	"7.83"	""	"3.33"	""	"1"	"protein metabolism;other metabolic processes;signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"11183"	"ENSG00000012983"	"MAP4K5"	"A0A0A0MQR1; hsa:11183; Q8IYF6; Q9Y4K4"	""	"Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Insulin signaling"	"3"	"0"	"31.1"	"18.4"	"36.2"	"26.8"	"24.5"	"25.5"	"37.6"	"0.1"	"222.0"	"213.7"	"452.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYW5"	"E3 ubiquitin-protein ligase RNF168 OS=Homo sapiens OX=9606 GN=RNF168 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"571"	"65.0"	"7.96"	"414.38"	"3.32"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14447"	"165918"	"ENSG00000163961"	"RNF168"	"hsa:165918; Q8IYW5; Q8NA67; Q96NS4"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; SUMOylation of DNA damage response and repair proteins; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"ATM signaling in development and disease ; 3q29 copy number variation syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"8"	"0"	"4.4"	"0.0"	"3.5"	"5.3"	"7.0"	"4.0"	"8.4"	"0.0"	"44.8"	"36.0"	"57.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4VC05"	"B-cell CLL/lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1"	"0.000"	""	"18"	"2"	"2"	"2"	"210"	"22.8"	"5.14"	"466.92"	"3.32"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf04714"	"605"	"ENSG00000110987; ENSG00000282873"	"BCL7A"	"B4DJN6; B7ZB21; hsa:605; Q13843; Q14CT7; Q4VC05"	""	""	"0"	"0"	"17.6"	"10.5"	"23.4"	"17.2"	"19.3"	"20.1"	"116.4"	"13.8"	"695.8"	"645.6"	"1377.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15649"	"Zinc finger HIT domain-containing protein 3 OS=Homo sapiens OX=9606 GN=ZNHIT3 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"155"	"17.6"	"5.67"	"406.02"	"3.32"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04438"	"9326"	"ENSG00000273611; ENSG00000278574"	"ZNHIT3"	"A8K493; hsa:9326; K7EQP1; Q15649; Q8WVJ3"	""	"17q12 copy number variation syndrome"	"1"	"0"	"45.5"	"36.5"	"37.9"	"32.8"	"39.7"	"27.2"	"80.5"	"0.0"	"333.0"	"327.8"	"621.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFY9"	"Kelch repeat and BTB domain-containing protein 8 OS=Homo sapiens OX=9606 GN=KBTBD8 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"601"	"68.8"	"6.29"	"314.69"	"3.32"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00651, Pf01344, Pf07707"	"84541"	"ENSG00000163376"	"KBTBD8"	"B4DTW6; hsa:84541; Q8NFY9; Q96JI5"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHA3"	"Probable ribosome biogenesis protein RLP24 OS=Homo sapiens OX=9606 GN=RSL24D1 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"163"	"19.6"	"9.98"	"280.03"	"3.32"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus"	"other molecular function"	"Pf01246"	"51187"	"ENSG00000137876"	"RSL24D1"	"B2RD72; hsa:51187; Q561V8; Q8N6S8; Q96B04; Q96C76; Q96HJ1; Q9UHA3"	""	""	"0"	"0"	"12.1"	"8.1"	"17.9"	"13.6"	"14.1"	"14.1"	"36.7"	"0.0"	"158.7"	"146.8"	"414.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96028"	"Histone-lysine N-methyltransferase NSD2 OS=Homo sapiens OX=9606 GN=NSD2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1365"	"152.2"	"8.69"	"396.25"	"3.32"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf00855, Pf00856, Pf17907, Pf17982"	"7468"	"ENSG00000109685"	"NSD2"	"A2A2T2; A2A2T3; A2A2T4; A7MCZ1; D3DVQ2; hsa:7468; O96028; O96031; Q4VBY8; Q672J1; Q6IS00; Q86V01; Q9BZB4; Q9UI92; Q9UPR2"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; PKMTs methylate histone lysines; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"4p16.3 copy number variation"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UE8"	"Serine/threonine-protein kinase tousled-like 2 OS=Homo sapiens OX=9606 GN=TLK2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"772"	"87.6"	"8.41"	"453.57"	"3.32"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"11011"	"ENSG00000146872"	"TLK2"	"D3DU07; hsa:11011; Q86UE8; Q9UKI7; Q9Y4F7"	""	"miRNA regulation of DNA damage response; DNA damage response"	"2"	"0"	"6.9"	"5.7"	"7.8"	"6.7"	"7.3"	"7.2"	"10.8"	"1.8"	"94.2"	"85.0"	"212.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y421"	"Protein FAM32A OS=Homo sapiens OX=9606 GN=FAM32A PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"112"	"13.2"	"9.99"	"395.81"	"3.31"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf08555"	"26017"	"ENSG00000105058"	"FAM32A"	"hsa:26017; Q9BT02; Q9Y421"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"26.6"	"17.8"	"19.8"	"27.7"	"24.9"	"19.0"	"46.7"	"0.0"	"437.2"	"486.6"	"842.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94762"	"ATP-dependent DNA helicase Q5 OS=Homo sapiens OX=9606 GN=RECQL5 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"991"	"108.8"	"8.56"	"382.97"	"3.31"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf06959, Pf16124"	"9400"	"ENSG00000108469"	"RECQL5"	"hsa:9400; O94762; Q6P4G0; Q9H0B1; Q9P1W7; Q9UNC8"	""	""	"0"	"0"	"8.1"	"6.8"	"8.2"	"10.6"	"8.2"	"10.4"	"17.4"	"0.5"	"55.2"	"42.1"	"77.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N2M8"	"CLK4-associating serine/arginine rich protein OS=Homo sapiens OX=9606 GN=CLASRP PE=1 SV=4"	""	""	"2"	"1"	"1"	"1"	"674"	"77.1"	"10.45"	""	"3.30"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf09750"	"11129"	"ENSG00000104859"	"CLASRP"	"B4DDT8; F8WAG9; hsa:11129; O96026; Q6UW71; Q8N2M8; Q96DX2"	""	"mRNA processing"	"1"	"0"	"19.7"	"15.1"	"19.5"	"22.6"	"17.5"	"30.8"	"33.3"	"1.4"	"98.4"	"109.3"	"188.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L4I2"	"Arginine/serine-rich coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=RSRC2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"434"	"50.5"	"11.33"	"655.95"	"3.30"	"2"	"1"	""	""	""	"Pf15477"	"65117"	"ENSG00000111011"	"RSRC2"	"hsa:65117; Q6N040; Q6NW16; Q7L4I2; Q9H864"	""	""	"0"	"0"	"241.0"	"136.1"	"159.3"	"178.7"	"180.0"	"146.8"	"256.5"	"0.0"	"1362.2"	"1231.8"	"2535.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P35610"	"Sterol O-acyltransferase 1 OS=Homo sapiens OX=9606 GN=SOAT1 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"550"	"64.7"	"8.94"	""	"3.30"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03062"	"6646"	"ENSG00000057252"	"SOAT1"	"A6NC40; A8K3P4; A9Z1V7; B4DU95; hsa:6646; P35610; Q5T0X4; Q8N1E4"	"LDL clearance"	"Statin inhibition of cholesterol production; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism"	"4"	"0"	"4.9"	"3.5"	"0.0"	"4.1"	"3.5"	"4.6"	"5.7"	"0.0"	"28.7"	"22.7"	"48.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75348"	"V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"118"	"13.7"	"8.79"	"280.15"	"3.30"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf03179"	"9550"	"ENSG00000136888"	"ATP6V1G1"	"hsa:9550; O75348; Q6IB33"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"Osteoclast signaling; Proximal tubule transport"	"7"	"0"	"29.9"	"19.5"	"37.5"	"43.1"	"36.5"	"21.3"	"76.0"	"0.0"	"335.5"	"352.6"	"697.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P219"	"Protein Daple OS=Homo sapiens OX=9606 GN=CCDC88C PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"1"	"2028"	"228.1"	"6.23"	"941.21"	"3.30"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf19047"	"440193"	"ENSG00000015133"	"CCDC88C"	"hsa:440193; Q69YK1; Q7L1M2; Q86SX7; Q8IYG8; Q9P219"	"Negative regulation of TCF-dependent signaling by DVL-interacting proteins"	"Ectoderm differentiation; Ectoderm differentiation"	"3"	"0"	"13.7"	"10.3"	"17.0"	"16.8"	"14.4"	"13.5"	"35.4"	"1.2"	"130.0"	"130.8"	"222.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15212"	"Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"129"	"14.6"	"8.88"	"327.57"	"3.30"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"10471"	"ENSG00000204220; ENSG00000206283; ENSG00000224782; ENSG00000235692; ENSG00000237335"	"PFDN6"	"hsa:10471; O15212"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"Cellular proteostasis"	"2"	"0"	"2.7"	"0.0"	"3.5"	"2.6"	"3.0"	"0.0"	"2.6"	"0.0"	"56.3"	"53.0"	"140.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFI3"	"Cytosolic endo-beta-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=ENGASE PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"743"	"83.9"	"6.79"	"388.71"	"3.30"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf03644"	"64772"	"ENSG00000167280"	"ENGASE"	"hsa:64772; Q659F0; Q8NFI3; Q8TB86; Q9H6U4"	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	""	"1"	"0"	"7.1"	"5.7"	"8.2"	"10.9"	"11.3"	"4.8"	"11.5"	"3.6"	"206.9"	"201.3"	"364.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H981"	"Actin-related protein 8 OS=Homo sapiens OX=9606 GN=ACTR8 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"624"	"70.4"	"7.78"	"602.89"	"3.30"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00022"	"93973"	"ENSG00000113812"	"ACTR8"	"B3KSW7; hsa:93973; Q8N566; Q9H663; Q9H981"	"UCH proteinases; DNA Damage Recognition in GG-NER"	""	"2"	"0"	"2.0"	"0.0"	"0.0"	"2.7"	"0.0"	"0.0"	"7.8"	"0.0"	"88.6"	"90.9"	"211.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6M5"	"Zinc transporter 1 OS=Homo sapiens OX=9606 GN=SLC30A1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"507"	"55.3"	"6.48"	"368.96"	"3.29"	"1"	"1"	"stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf01545"	"7779"	"ENSG00000170385"	"SLC30A1"	"hsa:7779; Q0VAK9; Q9BZF6; Q9Y6M5"	"Zinc efflux and compartmentalization by the SLC30 family"	"Zinc homeostasis"	"2"	"0"	"9.8"	"5.5"	"9.9"	"9.1"	"12.4"	"11.7"	"19.7"	"0.0"	"179.8"	"182.5"	"347.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H2K0"	"Translation initiation factor IF-3, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF3 PE=1 SV=4"	""	""	"3"	"1"	"1"	"1"	"278"	"31.7"	"9.69"	""	"3.29"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity;nucleic acid binding activity"	"Pf05198"	"219402"	"ENSG00000122033"	"MTIF3"	"hsa:219402; Q05BL8; Q5W0V0; Q86X68; Q9H2K0"	"Mitochondrial translation initiation"	""	"1"	"0"	"18.1"	"13.4"	"23.8"	"12.4"	"10.0"	"20.5"	"45.5"	"2.1"	"395.0"	"366.6"	"794.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7Z6"	"Histone acetyltransferase KAT8 OS=Homo sapiens OX=9606 GN=KAT8 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"458"	"52.4"	"8.27"	"447.32"	"3.28"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01853, Pf11717, Pf17772"	"84148"	"ENSG00000103510"	"KAT8"	"A8K4Z1; G5E9P2; hsa:84148; Q659G0; Q7LC17; Q8IY59; Q8WYB4; Q8WZ14; Q9H7Z6; Q9HAC5; Q9NR35"	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	""	"2"	"0"	"62.8"	"38.8"	"69.8"	"64.7"	"58.8"	"54.1"	"116.8"	"0.0"	"457.6"	"422.2"	"824.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP61"	"ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"516"	"56.9"	"7.36"	"452.67"	"3.28"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"26286"	"ENSG00000242247"	"ARFGAP3"	"E9PB03; hsa:26286; Q9BSC6; Q9H9J0; Q9NP61; Q9NT10; Q9NUP5; Q9Y4V3; Q9Y4V4"	"COPI-mediated anterograde transport; CDC42 GTPase cycle; RHOG GTPase cycle; COPI-dependent Golgi-to-ER retrograde traffic"	"Ciliary landscape"	"5"	"0"	"30.6"	"26.8"	"43.3"	"33.8"	"39.0"	"34.2"	"66.0"	"0.0"	"536.2"	"504.9"	"842.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TED0"	"U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"518"	"58.4"	"9.11"	"332.98"	"3.28"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	""	"Pf00400, Pf09384"	"84135"	"ENSG00000164338"	"UTP15"	"B4DU75; B4DXK8; hsa:84135; Q6IA60; Q8TED0; Q96E08; Q9H9F8"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16718"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3"	"0.000"	""	"9"	"1"	"2"	"1"	"116"	"13.5"	"5.99"	"291.76"	"3.28"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf04716"	"4698"	"ENSG00000128609"	"NDUFA5"	"B2RD98; hsa:4698; Q16718; Q5H9R2; Q6IRX7"	"Complex I biogenesis; RHOG GTPase cycle"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"7"	"0"	"4.3"	"3.5"	"14.9"	"5.6"	"9.6"	"9.0"	"19.1"	"0.0"	"378.4"	"390.7"	"685.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCF1"	"AN1-type zinc finger protein 1 OS=Homo sapiens OX=9606 GN=ZFAND1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"268"	"30.8"	"7.39"	"415.09"	"3.28"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf01428"	"79752"	"ENSG00000104231"	"ZFAND1"	"E5RIG0; E5RJ99; hsa:79752; Q658R7; Q6IA32; Q6PGQ6; Q8TCF1; Q9H810"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3Q1"	"Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"356"	"38.0"	"5.19"	"298.42"	"3.28"	"1"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00786, Pf14957"	"23580"	"ENSG00000179604"	"CDC42EP4"	"B3KUS7; hsa:23580; O95828; Q96FT3; Q9H3Q1"	"RAC1 GTPase cycle; RAC2 GTPase cycle; CDC42 GTPase cycle; RHOQ GTPase cycle"	""	"4"	"0"	"11.7"	"5.5"	"14.6"	"13.5"	"14.6"	"8.2"	"13.9"	"1.4"	"66.5"	"49.0"	"121.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGU0"	"Transcription factor 20 OS=Homo sapiens OX=9606 GN=TCF20 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"1960"	"211.6"	"9.04"	"324.19"	"3.27"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13771"	"6942"	"ENSG00000100207; ENSG00000262024; ENSG00000276461; ENSG00000280467; ENSG00000281897; ENSG00000282892; ENSG00000283026; ENSG00000283681"	"TCF20"	"A9JX12; hsa:6942; O14528; Q13078; Q4V353; Q9H4M0; Q9UGU0"	""	"Matrix metalloproteinases"	"1"	"0"	"64.5"	"50.9"	"66.1"	"65.5"	"59.1"	"80.1"	"194.7"	"0.0"	"533.1"	"541.2"	"1003.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15024"	"Exosome complex component RRP42 OS=Homo sapiens OX=9606 GN=EXOSC7 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"291"	"31.8"	"5.19"	""	"3.26"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"23016"	"ENSG00000075914"	"EXOSC7"	"hsa:23016; Q15024; Q96E72"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"Ciliary landscape"	"7"	"0"	"10.5"	"5.9"	"12.6"	"11.0"	"11.0"	"11.5"	"32.4"	"4.1"	"215.5"	"213.9"	"452.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P206"	"Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1035"	"107.0"	"9.73"	"443.94"	"3.25"	"1"	"1"	"other biological processes"	""	""	""	"57648"	"ENSG00000162522"	"KIAA1522"	"B4DQU8; B5MDY0; C9JH84; hsa:57648; Q8TCQ0; Q9P206"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P42224"	"Signal transducer and activator of transcription 1-alpha/beta OS=Homo sapiens OX=9606 GN=STAT1 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"750"	"87.3"	"6.05"	""	"3.25"	""	"1"	"cell cycle OR cell proliferation;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00017, Pf01017, Pf02864, Pf02865, Pf12162"	"6772"	"ENSG00000115415"	"STAT1"	"A8K989; B2RCA0; D2KFR8; D3DPI7; hsa:6772; P42224; Q53S88; Q53XW4; Q68D00; Q9UDL5"	"Downstream signal transduction; Regulation of RUNX2 expression and activity; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by SCF-KIT; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Interleukin-4 and Interleukin-13 signaling; Growth hormone receptor signaling; Interleukin-6 signaling; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; Signaling by cytosolic FGFR1 fusion mutants; Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH3 Intracellular Domain Regulates Transcription; Interleukin-20 family signaling; Interleukin-35 Signalling; Interleukin-27 signaling; Interleukin-9 signaling; Interleukin-21 signaling"	"IL-5 signaling pathway; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Type III interferon signaling; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; AGE/RAGE pathway; Allograft rejection; Interleukin-11 signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Endoderm differentiation; Kit receptor signaling pathway; IL6 signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; IL-4 signaling pathway; p38 MAPK signaling pathway; Immune response to tuberculosis; Ebola virus infection in host; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; IL-10 anti-inflammatory signaling pathway ; Overview of interferons-mediated signaling pathway; Measles virus infection; Tryptophan metabolism; Hepatitis B infection; Endochondral ossification; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; Endochondral ossification with skeletal dysplasias; TGF-beta receptor signaling in skeletal dysplasias; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; IL-2 signaling pathway; SARS coronavirus and innate immunity; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; CCL18 signaling pathway; Th17 cell differentiation pathway; Inflammatory bowel disease signaling; 2q13 copy number variation syndrome; TROP2 regulatory signaling; IL-26 signaling pathways; JAK-STAT signaling in the regulation of Beta-cells; TGF-beta receptor signaling; EPO receptor signaling; Interferon type I signaling pathways; Type II interferon signaling; Toll-like receptor signaling pathway"	"79"	"0"	"10.8"	"11.8"	"13.6"	"8.9"	"14.7"	"9.3"	"24.5"	"2.6"	"114.8"	"112.0"	"245.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G25"	"Mediator of RNA polymerase II transcription subunit 8 OS=Homo sapiens OX=9606 GN=MED8 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"268"	"29.1"	"7.44"	"315.59"	"3.25"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10232"	"112950"	"ENSG00000159479"	"MED8"	"A9IZ91; A9IZ92; hsa:112950; Q5JUY8; Q96FQ4; Q96G25"	"Generic Transcription Pathway; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	""	"3"	"0"	"6.0"	"4.6"	"9.3"	"7.8"	"11.7"	"3.2"	"18.4"	"1.9"	"136.8"	"120.6"	"286.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6QNY0"	"Biogenesis of lysosome-related organelles complex 1 subunit 3 OS=Homo sapiens OX=9606 GN=BLOC1S3 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"202"	"21.2"	"5.15"	"305.04"	"3.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;other cell component"	"transporter activity"	"Pf15753"	"388552"	"ENSG00000189114"	"BLOC1S3"	"B2RXB8; hsa:388552; Q6QNY0"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12694"	"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"445"	"50.4"	"8.27"	"359.52"	"3.25"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00676"	"593"	"ENSG00000248098"	"BCKDHA"	"B4DP47; E7EW46; hsa:593; P12694; Q16034; Q16472"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"Lipid metabolism pathway"	"3"	"0"	"29.8"	"27.0"	"34.3"	"30.8"	"35.1"	"28.4"	"64.8"	"0.0"	"344.5"	"319.0"	"584.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4E1"	"WASH complex subunit 2C OS=Homo sapiens OX=9606 GN=WASHC2C PE=1 SV=4"	"0.000"	""	"2"	"2"	"3"	"2"	"1320"	"144.8"	"4.79"	"229.82"	"3.24"	"1"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"26.0"	"18.0"	"28.7"	"24.4"	"27.8"	"27.3"	"44.9"	"1.1"	"473.0"	"440.1"	"945.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"B2RBV5"	"Putative MORF4 family-associated protein 1-like protein UPP OS=Homo sapiens OX=9606 PE=1 SV=1"	"0.000"	""	"10"	"1"	"2"	"1"	"119"	"13.4"	"8.22"	"341.00"	"3.24"	"1"	"1"	"other biological processes"	""	""	"Pf15155"	""	""	"MRFAP1L2"	"B2RBV5"	""	""	"0"	"0"	"3.8"	"0.0"	"5.1"	"6.1"	"5.7"	"4.9"	"10.1"	"0.8"	"69.0"	"76.9"	"123.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QT6"	"PHD finger protein 12 OS=Homo sapiens OX=9606 GN=PHF12 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1004"	"109.6"	"7.74"	"337.83"	"3.24"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628, Pf16737"	"57649"	"ENSG00000109118"	"PHF12"	"hsa:57649; Q0VAI5; Q2TAK2; Q6ZML2; Q96QT6; Q9BV34; Q9H7U9; Q9P205"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00410"	"Importin-5 OS=Homo sapiens OX=9606 GN=IPO5 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1097"	"123.6"	"4.94"	""	"3.24"	""	"1"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985, Pf18808, Pf18816, Pf18829"	"3843"	"ENSG00000065150"	"IPO5"	"B4DZA0; hsa:3843; O00410; O15257; Q5T578; Q86XC7"	"vRNP Assembly"	""	"1"	"0"	"3.1"	"0.0"	"3.3"	"3.3"	"0.0"	"0.0"	"0.0"	"0.0"	"19.8"	"26.0"	"61.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00268"	"Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1085"	"110.0"	"9.94"	"405.29"	"3.23"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf05236, Pf07531"	"6874"	"ENSG00000130699"	"TAF4"	"A6NGD9; hsa:6874; O00268; Q5TBP6; Q99721; Q9BR40; Q9BX42"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	""	"9"	"0"	"19.9"	"14.7"	"18.3"	"18.4"	"19.6"	"10.7"	"23.6"	"2.2"	"264.9"	"242.7"	"587.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46934"	"E3 ubiquitin-protein ligase NEDD4 OS=Homo sapiens OX=9606 GN=NEDD4 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1319"	"149.0"	"6.58"	"351.55"	"3.23"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00397, Pf00632"	"4734"	"ENSG00000069869"	"NEDD4"	"A1KY35; A6ND72; A7MD29; B4E2R7; B7ZM59; B7ZM60; B9EGN5; D6RF89; hsa:4734; P46934"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of PTEN stability and activity; ISG15 antiviral mechanism; Downregulation of ERBB4 signaling; Regulation of PTEN localization"	"Proteasome degradation; Ebola virus infection in host; EGF/EGFR signaling pathway; LDLRAD4 and what we know about it"	"9"	"0"	"6.3"	"4.8"	"4.8"	"7.8"	"9.8"	"8.0"	"8.6"	"0.0"	"139.0"	"163.0"	"358.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YP4"	"Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"633"	"68.0"	"9.94"	"405.65"	"3.23"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"54815"	"ENSG00000167491"	"GATAD2A"	"B5MC40; hsa:54815; Q7L3J2; Q86YP4; Q96F28; Q9NPU2; Q9NXS1"	"Potential therapeutics for SARS; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; HDACs deacetylate histones; Regulation of TP53 Activity through Acetylation"	""	"6"	"0"	"43.4"	"33.9"	"38.1"	"33.9"	"24.6"	"32.9"	"48.3"	"0.0"	"214.7"	"222.0"	"473.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T7V8"	"RAB6-interacting golgin OS=Homo sapiens OX=9606 GN=GORAB PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"394"	"45.0"	"7.08"	"297.35"	"3.22"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54289"	"Voltage-dependent calcium channel subunit alpha-2/delta-1 OS=Homo sapiens OX=9606 GN=CACNA2D1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1103"	"124.5"	"5.27"	"354.26"	"3.22"	"1"	"1"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf08399, Pf08473, Pf13768"	"781"	"ENSG00000153956"	"CACNA2D1"	"hsa:781; P54289; Q17R45; Q9UD80; Q9UD81; Q9UD82"	""	"Arrhythmogenic right ventricular cardiomyopathy; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Disturbed pathways in Duchenne Muscular Dystrophy"	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.1"	"2.2"	"4.0"	"1.7"	"29.3"	"32.8"	"54.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10472"	"Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"559"	"64.2"	"7.72"	"315.43"	"3.21"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00535, Pf00652"	"2589"	"ENSG00000141429"	"GALNT1"	"hsa:2589; Q10472; Q86TJ7; Q9UM86"	"COPI-independent Golgi-to-ER retrograde traffic; O-linked glycosylation of mucins; Maturation of protein 3a; Maturation of protein 3a"	"Metabolism of sphingolipids in ER and Golgi apparatus"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25786"	"Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"263"	"29.5"	"6.61"	"356.23"	"3.21"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5682"	"ENSG00000129084"	"PSMA1"	"A8K400; hsa:5682; P25786; Q53YE8; Q9BRV9"	"Ub-specific processing proteases; MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"71.3"	"42.2"	"67.3"	"93.9"	"81.0"	"65.0"	"53.3"	"0.0"	"278.3"	"227.3"	"719.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94763"	"Unconventional prefoldin RPB5 interactor 1 OS=Homo sapiens OX=9606 GN=URI1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"535"	"59.8"	"5.05"	"417.15"	"3.20"	"1"	"1"	"other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02996"	"8725"	"ENSG00000105176"	"URI1"	"A8K805; H7BY42; hsa:8725; O94763; Q8TC23; Q9UNU3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O94806"	"Serine/threonine-protein kinase D3 OS=Homo sapiens OX=9606 GN=PRKD3 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"890"	"100.4"	"6.87"	""	"3.20"	""	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;cytosol;nucleus"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00169"	"23683"	"ENSG00000115825"	"PRKD3"	"D6W587; hsa:23683; O94806; Q53TR7; Q8NEL8"	"Sphingolipid de novo biosynthesis"	"G protein signaling pathways; Hippo signaling regulation pathways; Chronic hyperglycemia impairment of neuron function"	"4"	"0"	"2.3"	"2.8"	"0.0"	"2.5"	"4.4"	"0.0"	"1.5"	"3.6"	"71.5"	"62.7"	"207.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95490"	"Adhesion G protein-coupled receptor L2 OS=Homo sapiens OX=9606 GN=ADGRL2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1459"	"163.2"	"6.43"	"433.84"	"3.19"	"1"	"1"	"developmental processes;signal transduction"	"other membranes;other cell component"	"other molecular function"	"Pf00002, Pf01825, Pf02140, Pf02191, Pf02354, Pf02793, Pf16489"	"23266"	"ENSG00000117114"	"ADGRL2"	"A5XEI2; B1ALT8; B1ALT9; B1ALU0; B1ALU2; B1ALU4; B1ALU5; B1ALU6; hsa:23266; O94882; O95490; Q5VX76; Q9UKY5; Q9UKY6"	""	"GPCRs, other; GPCRs, class B secretin-like"	"2"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.4"	"0.0"	"1.5"	"1.7"	"55.0"	"61.1"	"125.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16512"	"Serine/threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"942"	"103.9"	"6.37"	"352.35"	"3.19"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433, Pf02185"	"5585"	"ENSG00000123143"	"PKN1"	"A8K7W5; B2R9R4; B3KVN3; hsa:5585; Q15143; Q16512; Q504U4; Q8IUV5; Q9UD44"	"RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; RHOC GTPase cycle"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; PI3K-Akt signaling pathway; IL-18 signaling pathway; G13 signaling pathway"	"10"	"0"	"25.0"	"11.5"	"17.5"	"14.7"	"14.7"	"13.5"	"34.7"	"0.0"	"322.9"	"339.7"	"729.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92947"	"Glutaryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=GCDH PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"438"	"48.1"	"8.06"	"362.20"	"3.19"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"2639"	"ENSG00000105607"	"GCDH"	"A8K2Z2; hsa:2639; O14719; Q92947"	"Lysine catabolism"	"Fatty acid beta-oxidation; Tryptophan metabolism"	"3"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.7"	"0.0"	"6.3"	"0.0"	"34.7"	"38.8"	"73.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45880"	"Voltage-dependent anion-selective channel protein 2 OS=Homo sapiens OX=9606 GN=VDAC2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"294"	"31.5"	"7.56"	"281.76"	"3.18"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7417"	"ENSG00000165637"	"VDAC2"	"hsa:7417; P45880; Q5VWK1; Q5VWK3; Q6IB40; Q7L3J5; Q9BWK8; Q9Y5I6"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"Alzheimer's disease and miRNA effects; Ferroptosis; Alzheimer's disease"	"5"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.5"	"63.4"	"71.8"	"189.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GQ0"	"Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2"	"0.000"	""	"4"	"1"	"3"	"1"	"312"	"34.3"	"9.32"	"654.81"	"3.18"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf00106"	"51144"	"ENSG00000149084"	"HSD17B12"	"A8K9B0; D3DR23; hsa:51144; Q53GQ0; Q96EA9; Q96JU2; Q9Y6G8"	"Synthesis of very long-chain fatty acyl-CoAs; Androgen biosynthesis"	"Mitochondrial fatty acid synthesis pathway"	"3"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"3.5"	"0.0"	"36.1"	"43.8"	"102.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y605"	"MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"127"	"14.6"	"4.70"	"359.92"	"3.17"	"1"	"1"	""	"nucleus;other cell component"	""	"Pf15155"	"93621"	"ENSG00000179010"	"MRFAP1"	"B3KVT2; D3DVT3; hsa:93621; Q9Y605"	""	""	"0"	"0"	"54.9"	"31.6"	"53.7"	"41.6"	"42.3"	"37.2"	"72.0"	"0.8"	"262.7"	"247.6"	"525.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BD8"	"Spindle and kinetochore-associated protein 1 OS=Homo sapiens OX=9606 GN=SKA1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"255"	"29.5"	"7.12"	"268.40"	"3.17"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf07160"	"220134"	"ENSG00000154839; ENSG00000262634"	"SKA1"	"B2R9Y6; B4E0P4; hsa:220134; Q96BD8"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"9.7"	"7.8"	"15.6"	"9.7"	"11.9"	"8.8"	"15.3"	"4.1"	"120.3"	"114.2"	"239.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95926"	"Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"243"	"28.7"	"8.40"	"646.54"	"3.16"	"2"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf08231"	"25949"	"ENSG00000117614"	"SYF2"	"hsa:25949; O95926; Q5TH73"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"59.8"	"62.1"	"51.3"	"65.9"	"55.1"	"42.8"	"114.2"	"0.2"	"308.7"	"306.8"	"730.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW19"	"Kinesin-like protein KIFC1 OS=Homo sapiens OX=9606 GN=KIFC1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"673"	"73.7"	"8.98"	"310.06"	"3.16"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cytoplasmic organelle"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3833"	"ENSG00000204197; ENSG00000233450; ENSG00000237649"	"KIFC1"	"hsa:3833; O60887; Q14834; Q4KMP0; Q5SU09; Q6GMS7; Q6P4A5; Q9BW19; Q9UQP7"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92830"	"Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"837"	"93.9"	"9.04"	"275.74"	"3.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00583, Pf06466"	"2648"	"ENSG00000108773"	"KAT2A"	"hsa:2648; Q8N1A2; Q92830; Q9UCW1"	"Ub-specific processing proteases; B-WICH complex positively regulates rRNA expression; Pre-NOTCH Transcription and Translation; HATs acetylate histones; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Formation of WDR5-containing histone-modifying complexes; RNA Polymerase I Transcription Initiation; Cardiogenesis; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"Notch signaling"	"17"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13057"	"Bifunctional coenzyme A synthase OS=Homo sapiens OX=9606 GN=COASY PE=1 SV=4"	""	""	"2"	"1"	"1"	"1"	"564"	"62.3"	"6.99"	""	"3.15"	""	"1"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf01121, Pf01467"	"80347"	"ENSG00000068120"	"COASY"	"B2RA78; B4DLU0; hsa:80347; Q13057; Q6GS23; Q8NBM7; Q8NEW1; Q8WXD4; Q9NRM3"	"Coenzyme A biosynthesis"	"Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway"	"2"	"0"	"4.4"	"0.0"	"9.0"	"1.9"	"8.2"	"5.4"	"8.4"	"0.0"	"116.8"	"144.6"	"341.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFJ9"	"Bardet-Biedl syndrome 1 protein OS=Homo sapiens OX=9606 GN=BBS1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"593"	"65.0"	"7.93"	"417.46"	"3.14"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf14779"	"582"	"ENSG00000174483"	"BBS1"	"hsa:582; Q32MM9; Q32MN0; Q8NFJ9; Q96SN4"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	"0.0"	"2.4"	"3.1"	"0.0"	"2.6"	"2.3"	"5.5"	"0.0"	"52.4"	"49.1"	"135.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22314"	"Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1058"	"117.8"	"5.76"	"311.40"	"3.14"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"7317"	"ENSG00000130985"	"UBA1"	"hsa:7317; P22314; Q5JRR8; Q96E13"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"5"	"0"	"41.0"	"36.6"	"85.6"	"55.3"	"45.5"	"30.2"	"42.0"	"0.0"	"218.5"	"189.1"	"777.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14C86"	"GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1478"	"164.9"	"5.22"	"261.05"	"3.14"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf02204, Pf18151"	"26130"	"ENSG00000165219"	"GAPVD1"	"A8MYK3; B0QZ62; B0QZ63; B0QZ64; hsa:26130; Q14C76; Q14C86; Q2Q1W1; Q8ND92; Q8WU86; Q96CZ4; Q9NXQ1; Q9P207; Q9Y4N0"	"RAB GEFs exchange GTP for GDP on RABs; Clathrin-mediated endocytosis"	""	"2"	"0"	"6.1"	"5.1"	"5.1"	"6.0"	"7.7"	"6.8"	"9.7"	"1.6"	"79.2"	"87.7"	"192.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BTT4"	"Mediator of RNA polymerase II transcription subunit 10 OS=Homo sapiens OX=9606 GN=MED10 PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"135"	"15.7"	"6.19"	""	"3.14"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf09748"	"84246"	"ENSG00000133398"	"MED10"	"C6G491; hsa:84246; Q9BTT4"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	""	"3"	"0"	"3.1"	"2.0"	"5.9"	"4.5"	"7.6"	"5.5"	"12.3"	"0.0"	"97.5"	"81.7"	"169.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96TA1"	"Protein Niban 2 OS=Homo sapiens OX=9606 GN=NIBAN2 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"746"	"84.1"	"6.19"	""	"3.14"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	""	"64855"	"ENSG00000136830"	"NIBAN2"	"hsa:64855; Q4LE55; Q5VVW6; Q5VVW7; Q96TA1; Q9BUS2; Q9NT35"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94880"	"PHD finger protein 14 OS=Homo sapiens OX=9606 GN=PHF14 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"888"	"100.0"	"5.33"	"323.67"	"3.14"	"1"	"1"	""	""	"other molecular function"	"Pf00628, Pf13832"	"463265"	"ENSPTRG00000018935"	"PHF14"	"A0A2J8MED2; A0A6D2XU20; H2RCM0; ptr:463265"	""	""	"0"	"0"	"3.5"	"0.0"	"5.7"	"4.2"	"5.9"	"4.5"	"11.7"	"0.0"	"41.5"	"39.1"	"61.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MF7"	"E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"247"	"27.9"	"7.74"	"382.51"	"3.13"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf11789"	"286053"	"ENSG00000156831"	"NSMCE2"	"hsa:286053; Q8N549; Q96MF7"	"SUMOylation of DNA damage response and repair proteins"	""	"1"	"0"	"3.9"	"3.1"	"2.8"	"5.4"	"5.4"	"6.0"	"20.6"	"0.0"	"311.5"	"350.8"	"710.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92974"	"Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"986"	"111.5"	"7.27"	"459.92"	"3.13"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00621, Pf17838"	"9181"	"ENSG00000116584"	"ARHGEF2"	"D3DVA6; hsa:9181; O75142; Q15079; Q5VY92; Q8TDA3; Q8WUG4; Q92974; Q9H023"	"RHOA GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	"Pathogenic Escherichia coli infection"	"5"	"0"	"17.3"	"12.2"	"13.6"	"17.4"	"21.8"	"16.6"	"40.9"	"2.9"	"207.1"	"199.2"	"419.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EA4"	"Protein Spindly OS=Homo sapiens OX=9606 GN=SPDL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"605"	"70.1"	"5.47"	"319.04"	"3.13"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"54908"	"ENSG00000040275"	"SPDL1"	"B4E393; C9JS47; hsa:54908; Q8TEC8; Q96EA4; Q9HD44; Q9NX97"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"0.0"	"2.0"	"2.6"	"0.0"	"0.0"	"0.0"	"6.1"	"1.7"	"56.5"	"54.4"	"92.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75446"	"Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"220"	"23.3"	"9.17"	"260.47"	"3.12"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"8819"	"ENSG00000164105"	"SAP30"	"D3DP38; hsa:8819; O75446"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"Retinoblastoma gene in cancer; Notch signaling pathway"	"5"	"0"	"3.5"	"0.0"	"2.8"	"2.2"	"1.8"	"2.6"	"14.3"	"2.6"	"138.2"	"137.8"	"312.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRL2"	"Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"1556"	"178.6"	"6.60"	"719.02"	"3.12"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf02791, Pf10537, Pf15612, Pf15613"	"11177"	"ENSG00000198604"	"BAZ1A"	"hsa:11177; Q9NRL2; Q9NZ15; Q9P065; Q9UIG1; Q9Y3V3"	""	"Ectoderm differentiation"	"1"	"0"	"6.6"	"4.8"	"1.9"	"5.6"	"3.9"	"5.5"	"27.3"	"3.8"	"319.1"	"300.3"	"622.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18077"	"60S ribosomal protein L35a OS=Homo sapiens OX=9606 GN=RPL35A PE=1 SV=2"	"0.000"	""	"17"	"2"	"3"	"2"	"110"	"12.5"	"11.06"	"522.70"	"3.12"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01247"	"6165"	"ENSG00000182899"	"RPL35A"	"hsa:6165; P18077; Q08ES9; Q9BVN7"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"Cytoplasmic ribosomal proteins"	"14"	"0"	"38.7"	"18.7"	"38.7"	"32.9"	"34.8"	"40.8"	"156.1"	"1.1"	"513.9"	"576.6"	"743.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A0AVF1"	"Intraflagellar transport protein 56 OS=Homo sapiens OX=9606 GN=TTC26 PE=2 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"554"	"64.1"	"6.93"	"347.70"	"3.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf12895"	"79989"	"ENSG00000105948"	"IFT56"	"A0AVF1; A4D1S3; B7Z5M0; C9J2N7; F8W724; hsa:79989; Q9H9S8; Q9NTC0"	"Intraflagellar transport"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR)"	"3"	"0"	"0.0"	"0.0"	"4.9"	"3.8"	"5.5"	"2.1"	"6.2"	"1.9"	"71.9"	"89.9"	"214.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14757"	"Serine/threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"476"	"54.4"	"8.25"	"384.96"	"3.11"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1111"	"ENSG00000149554"	"CHEK1"	"A8K934; B4DDD0; B4DSK3; B5BTY6; F5H7S4; H2BI51; hsa:1111; O14757"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Transcriptional Regulation by E2F6; Signaling by SCF-KIT; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATR signaling; ATM signaling in development and disease ; DNA repair pathways, full network; TROP2 regulatory signaling; DNA damage response"	"18"	"0"	"10.9"	"11.5"	"13.4"	"10.3"	"18.9"	"9.6"	"18.6"	"1.8"	"114.5"	"127.8"	"279.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48047"	"ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"213"	"23.3"	"9.96"	"369.89"	"3.11"	"1"	"1"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00213"	"539"	"ENSG00000241837"	"ATP5PO"	"B2R4E2; hsa:539; P48047; Q5U042; Q6IBI2"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"5"	"0"	"47.3"	"49.6"	"56.9"	"49.2"	"64.5"	"54.8"	"92.9"	"0.0"	"536.2"	"600.1"	"1155.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18074"	"General transcription and DNA repair factor IIH helicase subunit XPD OS=Homo sapiens OX=9606 GN=ERCC2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"760"	"86.9"	"7.15"	"378.59"	"3.11"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06733, Pf06777, Pf13307"	"2068"	"ENSG00000104884"	"ERCC2"	"hsa:2068; P18074; Q2TB78; Q2YDY2; Q7KZU6; Q8N721"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Cytosolic iron-sulfur cluster assembly; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Fluoropyrimidine activity; Eukaryotic transcription initiation; Male infertility; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"36"	"0"	"6.7"	"5.1"	"6.8"	"5.8"	"10.2"	"11.8"	"6.5"	"2.4"	"71.5"	"80.7"	"164.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43488"	"Aflatoxin B1 aldehyde reductase member 2 OS=Homo sapiens OX=9606 GN=AKR7A2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"359"	"39.6"	"7.17"	"388.29"	"3.11"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00248"	"8574"	"ENSG00000053371"	"AKR7A2"	"hsa:8574; O43488; O75749; Q5TG63"	"Aflatoxin activation and detoxification"	"Aflatoxin B1 metabolism; Metapathway biotransformation Phase I and II"	"3"	"0"	"10.9"	"6.1"	"10.9"	"11.8"	"11.0"	"11.5"	"24.6"	"0.0"	"189.9"	"185.5"	"423.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAE8"	"Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"222"	"25.4"	"10.02"	"311.34"	"3.11"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf10147"	"90480"	"ENSG00000179271"	"GADD45GIP1"	"hsa:90480; Q8IVM3; Q8TAE8; Q8TE51; Q969P9; Q9BSM6"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"36.5"	"26.2"	"40.5"	"35.7"	"35.8"	"39.2"	"58.3"	"0.0"	"228.2"	"199.4"	"360.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53992"	"Protein transport protein Sec24C OS=Homo sapiens OX=9606 GN=SEC24C PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1094"	"118.2"	"7.06"	"301.52"	"3.11"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"9632"	"ENSG00000176986"	"SEC24C"	"B4DZT4; hsa:9632; P53992; Q8WV25"	"MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; COPII-mediated vesicle transport; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"7"	"0"	"5.9"	"4.1"	"9.4"	"5.4"	"7.9"	"3.5"	"19.2"	"1.3"	"121.1"	"128.1"	"262.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P17812"	"CTP synthase 1 OS=Homo sapiens OX=9606 GN=CTPS1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"591"	"66.6"	"6.46"	""	"3.11"	""	"1"	"cell cycle OR cell proliferation;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00117, Pf06418"	"1503"	"ENSG00000171793"	"CTPS1"	"B4DR64; D3DPW1; hsa:1503; P17812; Q5VW67; Q96GK6"	"Interconversion of nucleotide di- and triphosphates"	"Pyrimidine metabolism"	"2"	"0"	"4.2"	"0.0"	"5.6"	"3.9"	"5.6"	"6.6"	"11.3"	"0.0"	"136.0"	"148.0"	"315.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2H0"	"Disks large-associated protein 4 OS=Homo sapiens OX=9606 GN=DLGAP4 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"992"	"107.9"	"7.08"	"292.51"	"3.10"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf03359"	"22839"	"ENSG00000080845"	"DLGAP4"	"E1P5T5; hsa:22839; Q5QPG4; Q5T2Y4; Q5T2Y5; Q9H137; Q9H138; Q9H1L7; Q9Y2H0"	"Neurexins and neuroligins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95299"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"355"	"40.7"	"8.48"	"237.78"	"3.09"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;other cell component"	"transporter activity"	"Pf01712"	"4705"	"ENSG00000130414"	"NDUFA10"	"hsa:4705; O95299; Q8WXC9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; 2q37 copy number variation syndrome; Oxidative phosphorylation"	"6"	"0"	"15.5"	"11.3"	"14.8"	"13.8"	"16.1"	"7.1"	"37.4"	"3.3"	"224.2"	"216.3"	"471.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54709"	"Sodium/potassium-transporting ATPase subunit beta-3 OS=Homo sapiens OX=9606 GN=ATP1B3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"279"	"31.5"	"8.35"	"393.72"	"3.09"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"other molecular function"	"Pf00287"	"483"	"ENSG00000069849"	"ATP1B3"	"B7Z1N7; hsa:483; P54709"	"Ion transport by P-type ATPases; Potential therapeutics for SARS; Ion homeostasis; Basigin interactions"	"Calcium regulation in cardiac cells"	"5"	"0"	"9.0"	"6.8"	"11.7"	"14.1"	"14.8"	"16.6"	"25.6"	"4.8"	"329.2"	"325.9"	"701.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C4"	"EKC/KEOPS complex subunit TPRKB OS=Homo sapiens OX=9606 GN=TPRKB PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"175"	"19.6"	"6.79"	"246.96"	"3.09"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08617"	"51002"	"ENSG00000144034"	"TPRKB"	"D6W5H6; hsa:51002; Q8IWR6; Q8IWR7; Q9H3K4; Q9Y3C4"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"41.3"	"35.5"	"44.4"	"39.2"	"39.6"	"30.2"	"89.3"	"0.0"	"394.8"	"376.7"	"1017.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06547"	"GA-binding protein subunit beta-1 OS=Homo sapiens OX=9606 GN=GABPB1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"395"	"42.5"	"4.86"	"503.76"	"3.09"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf12796"	"2553"	"ENSG00000104064"	"GABPB1"	"A8IE52; hsa:2553; Q06545; Q06547; Q12940; Q12941; Q12942; Q8IYD0"	""	"Myometrial relaxation and contraction pathways; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; Mitochondrial gene expression"	"3"	"0"	"10.7"	"5.8"	"8.2"	"8.5"	"6.3"	"7.2"	"7.6"	"2.4"	"193.2"	"177.1"	"360.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96H20"	"Vacuolar-sorting protein SNF8 OS=Homo sapiens OX=9606 GN=SNF8 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"258"	"28.8"	"6.65"	""	"3.09"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04157"	"11267"	"ENSG00000159210"	"SNF8"	"hsa:11267; Q8IXY3; Q96H20; Q9UN50"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	""	"2"	"0"	"40.0"	"33.8"	"53.3"	"41.9"	"33.4"	"46.6"	"79.4"	"0.0"	"567.2"	"578.9"	"1145.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7Z3B4"	"Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"507"	"55.4"	"7.02"	""	"3.08"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;nucleus"	"other molecular function"	"Pf13874, Pf18437"	"53371"	"ENSG00000138750"	"NUP54"	"B2RCK7; B4DT35; hsa:53371; Q7Z3B4; Q96EA7; Q9NVL5; Q9P0I1"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Regulation of HSF1-mediated heat shock response; ISG15 antiviral mechanism; snRNP Assembly; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	""	"29"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.9"	"0.0"	"26.9"	"29.9"	"87.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31040"	"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"664"	"72.6"	"7.39"	"283.72"	"3.07"	"1"	"1"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00890, Pf02910"	"6389"	"ENSG00000073578"	"SDHA"	"A8K5J6; B4DJ60; E9PBJ5; hsa:6389; P31040; Q16395; Q59GW8; Q8IW48; Q9UMY5"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"Electron transport chain: OXPHOS system in mitochondria; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; Arsenic metabolism and reactive oxygen species generation; TCA cycle (aka Krebs or citric acid cycle)"	"9"	"0"	"57.7"	"50.8"	"32.0"	"50.5"	"49.8"	"37.1"	"75.7"	"1.1"	"379.8"	"343.9"	"641.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y3R0"	"Glutamate receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=GRIP1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"1128"	"122.3"	"6.47"	""	"3.07"	""	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00595, Pf17820"	"23426"	"ENSG00000155974"	"GRIP1"	"C9JT59; hsa:23426; Q1RLM0; Q9Y3R0"	"Trafficking of GluR2-containing AMPA receptors"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Fragile X syndrome; 7q11.23 copy number variation syndrome; Development of ureteric collection system"	"5"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.3"	"0.0"	"30.6"	"30.7"	"53.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P61956"	"Small ubiquitin-related modifier 2 OS=Homo sapiens OX=9606 GN=SUMO2 PE=1 SV=3"	""	""	"11"	"1"	"1"	"1"	"95"	"10.9"	"5.50"	""	"3.07"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11976"	"6613"	"ENSG00000188612"	"SUMO2"	"B2R4I2; hsa:6613; P55855; P61956; Q32Q42; Q6IPZ6; Q96HK1"	"SUMOylation of transcription cofactors; Formation of Incision Complex in GG-NER; SUMOylation of DNA damage response and repair proteins; Processing of DNA double-strand break ends; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; SUMOylation of intracellular receptors; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9); SUMO is proteolytically processed"	"TAR syndrome"	"15"	"0"	"14.6"	"11.4"	"23.6"	"15.5"	"17.0"	"12.7"	"24.6"	"0.0"	"106.9"	"120.5"	"376.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6H8Y1"	"Transcription factor TFIIIB component B'' homolog OS=Homo sapiens OX=9606 GN=BDP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2624"	"293.7"	"5.11"	"352.82"	"3.07"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf15963"	"55814"	"ENSG00000145734; ENSG00000273873"	"BDP1"	"A6H8Y1; hsa:55814; Q68DS6; Q68DY5; Q6MZL9; Q6PIM7; Q86W98; Q96LR8; Q9C0H4; Q9H197; Q9H1A1; Q9HAW1; Q9HAW2; Q9HCY0; Q9ULH9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43665"	"Regulator of G-protein signaling 10 OS=Homo sapiens OX=9606 GN=RGS10 PE=1 SV=3"	""	""	"6"	"1"	"1"	"1"	"181"	"21.2"	"7.49"	""	"3.07"	""	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00615"	"6001"	"ENSG00000148908"	"RGS10"	"A8K408; B1AMR8; hsa:6001; O43665; Q6IAZ6; Q96GN0"	"G alpha (i) signalling events"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells"	"4"	"0"	"0.0"	"0.0"	"2.5"	"0.0"	"0.0"	"0.0"	"0.0"	"1.6"	"37.2"	"40.1"	"102.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60237"	"Protein phosphatase 1 regulatory subunit 12B OS=Homo sapiens OX=9606 GN=PPP1R12B PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"982"	"110.3"	"5.67"	"344.86"	"3.07"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00023, Pf13637, Pf15898"	"4660"	"ENSG00000077157"	"PPP1R12B"	"A0A0A0MS24; A8MYF5; B7ZMN6; hsa:4660; O60237; Q2TAI8; Q5T506; Q5VUK2; Q8N179; Q9HCB7; Q9HCB8"	"RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"Focal adhesion"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXC9"	"Bardet-Biedl syndrome 2 protein OS=Homo sapiens OX=9606 GN=BBS2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"721"	"79.8"	"6.15"	"390.07"	"3.06"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"7.1"	"6.5"	"15.4"	"12.4"	"12.4"	"14.8"	"27.5"	"0.0"	"333.8"	"328.6"	"575.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15831"	"Serine/threonine-protein kinase STK11 OS=Homo sapiens OX=9606 GN=STK11 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"433"	"48.6"	"7.43"	"310.67"	"3.06"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"6794"	"ENSG00000118046"	"STK11"	"B2RBX7; E7EW76; hsa:6794; Q15831"	"Regulation of TP53 Activity through Phosphorylation; Energy dependent regulation of mTOR by LKB1-AMPK; FOXO-mediated transcription of cell death genes; AMPK inhibits chREBP transcriptional activation activity"	"AMP-activated protein kinase signaling; mir-124 predicted interactions with cell cycle and differentiation ; ATM signaling in development and disease ; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Female steroid hormones in cardiomyocyte energy metabolism"	"12"	"0"	"6.6"	"2.8"	"4.7"	"4.1"	"4.2"	"5.2"	"12.3"	"0.0"	"231.4"	"188.8"	"304.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z460"	"CLIP-associating protein 1 OS=Homo sapiens OX=9606 GN=CLASP1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1538"	"169.3"	"9.03"	"326.78"	"3.06"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"23332"	"ENSG00000074054"	"CLASP1"	"A2RU21; B7ZLX3; F5GWS0; hsa:23332; O75118; Q2KHQ9; Q5H9P0; Q7Z460; Q8N5B8; Q9BQT5"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Role of ABL in ROBO-SLIT signaling"	"Microtubule cytoskeleton regulation; Splicing factor NOVA regulated synaptic proteins; 7q11.23 copy number variation syndrome"	"17"	"0"	"5.2"	"3.6"	"6.7"	"6.5"	"5.3"	"4.9"	"13.7"	"1.9"	"74.3"	"82.0"	"154.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75792"	"Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"299"	"33.4"	"5.25"	""	"3.05"	""	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01351"	"10535"	"ENSG00000104889"	"RNASEH2A"	"B2RCY1; hsa:10535; O75792; Q96F11"	""	""	"0"	"0"	"31.5"	"17.6"	"43.4"	"32.0"	"28.3"	"23.9"	"38.7"	"0.0"	"730.1"	"700.2"	"1517.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YT6"	"E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens OX=9606 GN=MIB1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1006"	"110.1"	"6.92"	"280.93"	"3.05"	"1"	"1"	"protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00569, Pf06701, Pf12796, Pf13920, Pf18346"	"57534"	"ENSG00000101752"	"MIB1"	"B0YJ38; hsa:57534; Q2TB37; Q68D01; Q6YI51; Q86YT6; Q8NBY0; Q8TCB5; Q8TCL7; Q9P2M3"	"Activated NOTCH1 Transmits Signal to the Nucleus; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus"	"Genes related to primary cilium development (based on CRISPR)"	"7"	"0"	"7.5"	"6.3"	"6.3"	"4.3"	"4.4"	"5.0"	"9.9"	"0.0"	"87.1"	"78.1"	"157.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWU2"	"Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"228"	"26.7"	"4.97"	"295.05"	"3.05"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08513, Pf10607"	"54994"	"ENSG00000101193"	"GID8"	"E1P5I3; hsa:54994; Q8N5M5; Q9NWU2"	""	"Ciliary landscape"	"1"	"0"	"2.5"	"0.0"	"6.4"	"7.3"	"10.6"	"7.1"	"19.2"	"0.0"	"179.3"	"164.6"	"329.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13257"	"Mitotic spindle assembly checkpoint protein MAD2A OS=Homo sapiens OX=9606 GN=MAD2L1 PE=1 SV=1"	""	""	"11"	"1"	"1"	"1"	"205"	"23.5"	"5.08"	""	"3.04"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf02301"	"4085"	"ENSG00000164109"	"MAD2L1"	"hsa:4085; Q13257; Q53F56; Q548X9; Q6IRW7; Q8IZX3"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"Regulation of sister chromatid separation at the metaphase-anaphase transition; Pleural mesothelioma"	"13"	"0"	"2.5"	"0.0"	"3.3"	"4.2"	"6.7"	"2.8"	"6.7"	"0.7"	"54.7"	"57.0"	"165.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60825"	"6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"505"	"58.4"	"8.38"	"314.75"	"3.04"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf00300, Pf01591"	"5208"	"ENSG00000123836"	"PFKFB2"	"hsa:5208; O60824; O60825; Q5VVQ3; Q5VVQ4; Q9H3P1"	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	"3"	"0"	"0.0"	"2.2"	"2.5"	"1.7"	"0.0"	"0.0"	"4.3"	"0.0"	"33.1"	"26.7"	"87.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VUA4"	"Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2279"	"251.0"	"7.20"	"272.93"	"3.03"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"24149"	"ENSG00000171467"	"ZNF318"	"hsa:24149; O94796; Q4G0E4; Q5VUA4; Q8NEM6; Q9UNU8; Q9Y2W9"	""	"Androgen receptor signaling pathway"	"1"	"0"	"7.6"	"5.6"	"5.3"	"2.4"	"2.5"	"7.4"	"5.3"	"0.0"	"51.5"	"48.6"	"80.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P63218"	"Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-5 OS=Homo sapiens OX=9606 GN=GNG5 PE=1 SV=3"	""	""	"13"	"1"	"1"	"1"	"68"	"7.3"	"9.85"	""	"3.03"	""	"1"	"signal transduction"	"plasma membrane;other membranes"	"other molecular function"	"Pf00631"	"2787"	"ENSG00000174021"	"GNG5"	"B2R5A0; hsa:2787; P30670; P63218; Q5VX54; Q61015"	"G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"35"	"0"	"24.9"	"17.6"	"41.3"	"26.8"	"23.9"	"24.4"	"43.1"	"0.0"	"806.2"	"847.7"	"1852.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVQ7"	"Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"753"	"80.7"	"8.09"	"289.67"	"3.03"	"1"	"1"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"79029"	"ENSG00000171763"	"AFG2B"	"C9JHR5; hsa:79029; Q9BVQ7; Q9H8W7; Q9HA41"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95983"	"Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"291"	"32.8"	"5.34"	"1035.83"	"3.03"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"53615"	"ENSG00000071655"	"MBD3"	"A8K4B7; D6W5Z2; hsa:53615; O95983; Q6PIL9; Q6PJZ9; Q86XF4"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"7"	"0"	"118.2"	"74.3"	"107.3"	"91.5"	"92.6"	"82.7"	"146.6"	"1.7"	"573.4"	"578.0"	"1413.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N9I9"	"Probable E3 ubiquitin-protein ligase DTX3 OS=Homo sapiens OX=9606 GN=DTX3 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"347"	"38.0"	"8.73"	""	"3.02"	""	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other cell component"	"other molecular function"	"Pf13923, Pf18102"	"196403"	"ENSG00000178498"	"DTX3"	"hsa:196403; Q53ZZ2; Q8N9I9; Q8NAU6; Q8NDS8"	""	"Notch signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14737"	"Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"125"	"14.3"	"6.04"	"346.58"	"3.02"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01984"	"9141"	"ENSG00000105185"	"PDCD5"	"B4DE64; hsa:9141; O14737; Q53YC9; Q6IB70"	""	""	"0"	"0"	"4.0"	"6.5"	"9.9"	"3.7"	"7.3"	"5.0"	"9.2"	"0.0"	"17.5"	"13.2"	"59.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54098"	"DNA polymerase subunit gamma-1 OS=Homo sapiens OX=9606 GN=POLG PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"1239"	"139.5"	"6.90"	"352.67"	"3.02"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00476, Pf18136"	"5428"	"ENSG00000140521"	"POLG"	"hsa:5428; P54098; Q8NFM2; Q92515"	""	"Male infertility; Primary ovarian insufficiency"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13489"	"Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"461"	"49.9"	"4.82"	"369.62"	"3.02"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf13516, Pf18779"	"6050"	"ENSG00000023191; ENSG00000276230"	"RNH1"	"hsa:6050; P13489; Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6"	""	""	"0"	"0"	"69.3"	"41.8"	"78.0"	"77.8"	"68.0"	"37.5"	"83.4"	"0.0"	"331.4"	"323.4"	"758.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5VIR6"	"Vacuolar protein sorting-associated protein 53 homolog OS=Homo sapiens OX=9606 GN=VPS53 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"699"	"79.6"	"6.02"	""	"3.01"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"7.2"	"2.1"	"6.2"	"3.6"	"4.9"	"7.5"	"15.5"	"5.6"	"305.2"	"289.2"	"580.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95478"	"Ribosome biogenesis protein NSA2 homolog OS=Homo sapiens OX=9606 GN=NSA2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"260"	"30.0"	"10.27"	"361.33"	"3.01"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01201"	"10412"	"ENSG00000164346"	"NSA2"	"hsa:10412; O95478"	""	""	"0"	"0"	"8.1"	"8.8"	"7.6"	"9.6"	"15.8"	"11.8"	"25.7"	"5.1"	"111.8"	"125.4"	"208.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N0X4"	"Citramalyl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=CLYBL PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"340"	"37.3"	"8.73"	"354.31"	"3.01"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03328"	"171425"	"ENSG00000125246"	"CLYBL"	"hsa:171425; Q5W0F7; Q8N0X4; Q8TDH8"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"3.0"	"4.4"	"5.9"	"25.2"	"0.7"	"313.6"	"271.2"	"513.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H8V3"	"Protein ECT2 OS=Homo sapiens OX=9606 GN=ECT2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"914"	"103.4"	"7.71"	""	"3.01"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00533, Pf00621, Pf12738"	"1894"	"ENSG00000114346"	"ECT2"	"hsa:1894; Q0MT80; Q2M269; Q6U836; Q9H8V3; Q9NSV8; Q9NVW9"	"RHOA GTPase cycle; RHOB GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events"	"Gastric cancer network 1"	"7"	"0"	"0.0"	"0.0"	"3.0"	"0.0"	"3.3"	"0.0"	"3.0"	"3.2"	"73.0"	"71.9"	"162.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JP5"	"E3 ubiquitin-protein ligase ZFP91 OS=Homo sapiens OX=9606 GN=ZFP91 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"570"	"63.4"	"7.36"	"455.88"	"3.00"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf00096"	"80829"	"ENSG00000186660"	"ZFP91"	"A6NHC4; A8MSG7; hsa:80829; Q86V47; Q96JP4; Q96JP5; Q96QA3"	""	""	"0"	"0"	"19.4"	"18.5"	"18.3"	"15.6"	"12.0"	"19.7"	"28.5"	"0.0"	"96.9"	"100.5"	"181.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53H47"	"Histone-lysine N-methyltransferase SETMAR OS=Homo sapiens OX=9606 GN=SETMAR PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"684"	"78.0"	"7.14"	"361.95"	"3.00"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf01359, Pf05033, Pf17906"	"6419"	"ENSG00000170364"	"SETMAR"	"B4DY74; E7EN68; hsa:6419; Q13579; Q1G668; Q53H47; Q96F41"	""	"Histone modifications"	"1"	"0"	"5.0"	"0.0"	"2.2"	"2.8"	"1.8"	"0.0"	"2.1"	"0.0"	"51.5"	"50.3"	"146.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC62"	"Sentrin-specific protease 2 OS=Homo sapiens OX=9606 GN=SENP2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"589"	"67.8"	"9.48"	"285.58"	"3.00"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02902"	"59343"	"ENSG00000163904"	"SENP2"	"B4DQ42; hsa:59343; Q8IW97; Q96SR2; Q9HC62; Q9P2L5"	"SUMO is proteolytically processed"	"lncRNA in canonical Wnt signaling and colorectal cancer; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Pleural mesothelioma"	"5"	"0"	"8.4"	"0.0"	"13.3"	"10.8"	"12.2"	"9.4"	"18.9"	"0.2"	"58.5"	"72.4"	"121.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12846"	"Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"297"	"34.2"	"6.28"	"301.44"	"2.99"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00804, Pf05739"	"6810"	"ENSG00000103496"	"STX4"	"A8MXY0; hsa:6810; Q12846; Q15525; Q6FHE8"	"ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; trans-Golgi Network Vesicle Budding; Disinhibition of SNARE formation; Other interleukin signaling"	"Insulin signaling"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZL1"	"Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1"	"0.000"	""	"26"	"2"	"3"	"2"	"73"	"8.5"	"8.44"	"708.85"	"2.99"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00240"	"59286"	"ENSG00000198258"	"UBL5"	"hsa:59286; Q2NL89; Q9BZL1"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"40.5"	"39.1"	"48.1"	"49.0"	"37.6"	"42.4"	"105.2"	"2.8"	"725.3"	"743.3"	"1512.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H583"	"HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2144"	"242.2"	"6.54"	"348.78"	"2.99"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf08146, Pf12397"	"55127"	"ENSG00000119285"	"HEATR1"	"hsa:55127; Q5T3Q8; Q6P197; Q9H583; Q9NW23"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"4.0"	"3.4"	"7.1"	"3.2"	"4.6"	"3.3"	"8.7"	"0.0"	"45.6"	"51.3"	"72.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35998"	"26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3"	"0.000"	""	"7"	"3"	"4"	"3"	"433"	"48.6"	"5.95"	"1119.88"	"2.98"	"3"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"5701"	"ENSG00000161057"	"PSMC2"	"A4D0Q1; B7Z5E2; hsa:5701; P35998; Q3LIA5; Q9UDI3"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"64"	"0"	"71.0"	"47.2"	"91.2"	"77.1"	"56.9"	"62.1"	"166.2"	"9.8"	"635.7"	"586.7"	"1377.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05655"	"Protein kinase C delta type OS=Homo sapiens OX=9606 GN=PRKCD PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"676"	"77.5"	"7.75"	"306.03"	"2.98"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433"	"5580"	"ENSG00000163932"	"PRKCD"	"B0KZ81; B2R834; hsa:5580; Q05655; Q15144; Q86XJ6"	"CLEC7A (Dectin-1) signaling; KEAP1-NFE2L2 pathway; Neutrophil degranulation; Interferon gamma signaling; Role of phospholipids in phagocytosis; G alpha (z) signalling events; SHC1 events in ERBB2 signaling; HuR (ELAVL1) binds and stabilizes mRNA; VEGFR2 mediated cell proliferation; DAG and IP3 signaling; Effects of PIP2 hydrolysis; RHO GTPases Activate NADPH Oxidases; Calmodulin induced events; Apoptotic cleavage of cellular proteins"	"Type II diabetes mellitus; Glioblastoma signaling pathways; B cell receptor signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; IL6 signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Wnt signaling pathway and pluripotency; Pancreatic adenocarcinoma pathway; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Hippo signaling regulation pathways; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; IL-18 signaling pathway; Osteoblast differentiation and related diseases; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Galanin receptor pathway; Orexin receptor pathway; CCL18 signaling pathway; Chronic hyperglycemia impairment of neuron function; TROP2 regulatory signaling; Calcium regulation in cardiac cells; Type II interferon signaling; T-cell receptor signaling pathway"	"47"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"25.6"	"31.1"	"72.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15265"	"Ataxin-7 OS=Homo sapiens OX=9606 GN=ATXN7 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"892"	"95.4"	"9.85"	"372.08"	"2.98"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf08313"	"6314"	"ENSG00000163635"	"ATXN7"	"B4E207; E9PHP9; hsa:6314; O15265; O75328; O75329; Q9Y6P8"	"Ub-specific processing proteases; HATs acetylate histones"	""	"2"	"0"	"3.9"	"3.0"	"0.0"	"2.9"	"3.2"	"2.2"	"2.8"	"1.6"	"30.7"	"29.1"	"59.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWT3"	"Poly(A) polymerase gamma OS=Homo sapiens OX=9606 GN=PAPOLG PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"736"	"82.8"	"9.14"	"252.86"	"2.98"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"64895"	"ENSG00000115421"	"PAPOLG"	"B2RBH4; hsa:64895; Q59G05; Q969N1; Q9BWT3; Q9H8L2; Q9HAD0"	""	""	"0"	"0"	"3.7"	"2.8"	"8.3"	"6.8"	"7.1"	"5.0"	"10.1"	"2.2"	"101.4"	"94.0"	"227.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96S55"	"ATPase WRNIP1 OS=Homo sapiens OX=9606 GN=WRNIP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"665"	"72.1"	"6.10"	"511.96"	"2.98"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00004, Pf12002, Pf16193, Pf18279"	"56897"	"ENSG00000124535"	"WRNIP1"	"B2RDB0; hsa:56897; Q53EP6; Q59ET8; Q5W0E2; Q5W0E4; Q8WV26; Q96S55; Q9H681; Q9NRJ6"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.4"	"0.0"	"23.3"	"37.0"	"145.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWX6"	"Probable tRNA(His) guanylyltransferase OS=Homo sapiens OX=9606 GN=THG1L PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"298"	"34.8"	"8.00"	"274.87"	"2.97"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response"	"other membranes;cytosol;mitochondrion;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf04446, Pf14413"	"54974"	"ENSG00000113272"	"THG1L"	"D3DQJ5; hsa:54974; Q53G12; Q7L5R3; Q9H0S2; Q9NWX6"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.5"	"0.0"	"0.9"	"1.5"	"36.2"	"42.4"	"109.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75054"	"Immunoglobulin superfamily member 3 OS=Homo sapiens OX=9606 GN=IGSF3 PE=2 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1194"	"135.1"	"6.07"	"264.90"	"2.97"	"1"	"1"	"developmental processes"	"other membranes"	""	"Pf07686"	"3321"	"ENSG00000143061"	"IGSF3"	"A6NJZ6; A6NMC7; hsa:3321; O75054"	""	""	"0"	"0"	"8.7"	"3.6"	"15.5"	"10.4"	"11.2"	"5.7"	"8.3"	"0.0"	"174.8"	"157.8"	"334.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q06203"	"Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"517"	"57.4"	"6.76"	""	"2.97"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00156, Pf13522"	"5471"	"ENSG00000128059"	"PPAT"	"hsa:5471; Q06203"	"Purine ribonucleoside monophosphate biosynthesis"	"Fluoropyrimidine activity; Metabolic reprogramming in colon cancer"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14964"	"Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"777"	"86.1"	"6.16"	""	"2.96"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00790, Pf01363, Pf12210"	"9146"	"ENSG00000185359"	"HGS"	"hsa:9146; O14964; Q9NR36"	"Endosomal Sorting Complex Required For Transport (ESCRT); Ub-specific processing proteases; Lysosome Vesicle Biogenesis; RHOU GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Inhibition of membrane repair; Prevention of phagosomal-lysosomal fusion; RHOBTB3 ATPase cycle"	"VEGFA-VEGFR2 signaling; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; EGF/EGFR signaling pathway"	"15"	"0"	"11.0"	"6.4"	"11.5"	"17.5"	"13.0"	"15.0"	"19.0"	"2.9"	"195.7"	"183.0"	"547.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07864"	"DNA polymerase epsilon catalytic subunit A OS=Homo sapiens OX=9606 GN=POLE PE=1 SV=5"	"0.000"	""	"1"	"1"	"2"	"1"	"2286"	"261.4"	"6.39"	"265.03"	"2.95"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08490"	"5426"	"ENSG00000177084"	"POLE"	"hsa:5426; Q07864; Q13533; Q86VH9"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"19"	"0"	"6.0"	"3.3"	"5.6"	"4.0"	"8.0"	"8.4"	"10.5"	"1.6"	"113.5"	"104.4"	"187.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y6V7"	"Probable ATP-dependent RNA helicase DDX49 OS=Homo sapiens OX=9606 GN=DDX49 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"483"	"54.2"	"9.06"	""	"2.95"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"54555"	"ENSG00000105671"	"DDX49"	"E7ENA0; hsa:54555; Q53FJ1; Q9BVQ8; Q9Y6V7"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"5.1"	"0.0"	"5.0"	"0.0"	"3.0"	"0.0"	"5.0"	"0.9"	"57.3"	"54.8"	"205.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P48382"	"DNA-binding protein RFX5 OS=Homo sapiens OX=9606 GN=RFX5 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"616"	"65.3"	"9.29"	""	"2.95"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02257, Pf14621, Pf18326"	"5993"	"ENSG00000143390"	"RFX5"	"B7Z848; D3DV19; E9PFU4; hsa:5993; P48382; Q5VWC3"	""	"Prion disease pathway; IL-18 signaling pathway"	"2"	"0"	"3.1"	"2.4"	"5.0"	"13.0"	"9.9"	"9.4"	"13.5"	"0.8"	"55.8"	"50.2"	"122.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31930"	"Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"480"	"52.6"	"6.37"	"380.89"	"2.94"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00675, Pf05193"	"7384"	"ENSG00000010256"	"UQCRC1"	"B2R7R8; hsa:7384; P31930; Q96DD2"	"Respiratory electron transport"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"4"	"0"	"5.8"	"5.2"	"6.6"	"5.8"	"3.8"	"5.2"	"8.3"	"0.0"	"47.8"	"53.8"	"84.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUL8"	"Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"212"	"24.7"	"8.19"	"329.20"	"2.94"	"1"	"1"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06840"	"11235"	"ENSG00000114209"	"PDCD10"	"A8K515; D3DNN5; hsa:11235; O14811; Q9BUL8"	""	""	"0"	"0"	"28.4"	"12.3"	"24.2"	"28.8"	"19.6"	"25.4"	"71.3"	"0.0"	"392.5"	"484.3"	"974.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVG4"	"Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"233"	"26.0"	"4.79"	"323.36"	"2.94"	"1"	"1"	""	""	""	"Pf04669"	"51260"	"ENSG00000102390"	"PBDC1"	"hsa:51260; Q9BVG4"	""	""	"0"	"0"	"7.8"	"7.6"	"6.7"	"5.0"	"6.9"	"7.0"	"17.9"	"1.0"	"196.6"	"204.2"	"331.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68D85"	"Natural cytotoxicity triggering receptor 3 ligand 1 OS=Homo sapiens OX=9606 GN=NCR3LG1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"454"	"50.8"	"5.59"	"350.16"	"2.93"	"1"	"1"	""	"plasma membrane;other membranes"	""	"Pf07654"	"374383"	"ENSG00000188211"	"NCR3LG1"	"hsa:374383; Q68D85; Q7Z3M6"	"Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell"	"Interactions of natural killer cells in pancreatic cancer"	"2"	"0"	"3.9"	"0.0"	"3.1"	"0.0"	"0.0"	"0.0"	"2.5"	"0.0"	"34.0"	"40.5"	"66.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9C091"	"GREB1-like protein OS=Homo sapiens OX=9606 GN=GREB1L PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1923"	"214.2"	"6.62"	""	"2.93"	""	"1"	"developmental processes"	"other membranes"	""	"Pf15782, Pf20267"	"80000"	"ENSG00000141449"	"GREB1L"	"A4QN17; hsa:80000; Q9C091; Q9H8F1"	""	"Development of ureteric collection system"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68DQ2"	"Very large A-kinase anchor protein OS=Homo sapiens OX=9606 GN=CRYBG3 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2970"	"330.4"	"5.20"	"334.27"	"2.93"	"1"	"1"	"developmental processes;other biological processes"	"other cell component"	"other molecular function"	"Pf00030, Pf00652"	"131544"	"ENSG00000080200"	"CRYBG3"	"B4DLE8; F6VHI2; hsa:131544; Q4G0V8; Q68DQ2; Q7Z4R9; Q86VD0; Q8N262; Q8N7F1; Q8NDQ8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NYC1"	"Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 OS=Homo sapiens OX=9606 GN=JMJD6 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"403"	"46.4"	"8.69"	"298.33"	"2.93"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"23210"	"ENSG00000070495"	"JMJD6"	"B3KMN8; B4DGX1; hsa:23210; Q6NYC1; Q86VY0; Q8IUM5; Q9Y4E2"	"HDMs demethylate histones"	""	"1"	"0"	"44.0"	"42.5"	"36.7"	"38.6"	"45.3"	"42.8"	"58.5"	"0.0"	"223.2"	"222.3"	"410.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IWZ6"	"Bardet-Biedl syndrome 7 protein OS=Homo sapiens OX=9606 GN=BBS7 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"715"	"80.3"	"6.05"	""	"2.92"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"55212"	"ENSG00000138686"	"BBS7"	"hsa:55212; Q4W5P8; Q8IWZ6; Q8N581; Q9NVI4"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q969J3"	"BLOC-1-related complex subunit 5 OS=Homo sapiens OX=9606 GN=BORCS5 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"196"	"22.2"	"6.35"	""	"2.92"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf10158"	"118426"	"ENSG00000165714; ENSG00000280689"	"BORCS5"	"hsa:118426; Q969J3; Q96QS5"	""	""	"0"	"0"	"0.0"	"2.3"	"0.0"	"0.0"	"0.0"	"0.0"	"2.7"	"1.4"	"50.3"	"44.3"	"95.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRX8"	"Peroxiredoxin-like 2A OS=Homo sapiens OX=9606 GN=PRXL2A PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"229"	"25.7"	"8.84"	"334.60"	"2.92"	"1"	"1"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf13911"	"84293"	"ENSG00000122378"	"PRXL2A"	"B2RD81; hsa:84293; Q6UW08; Q8N2K3; Q8NBK9; Q96JR0; Q9BRX8"	""	"10q22q23 copy number variation"	"1"	"0"	"0.0"	"0.0"	"2.7"	"3.6"	"0.0"	"0.0"	"2.3"	"0.0"	"26.2"	"35.0"	"68.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4X5"	"E3 ubiquitin-protein ligase ARIH1 OS=Homo sapiens OX=9606 GN=ARIH1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"557"	"64.1"	"5.08"	"265.63"	"2.92"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01485, Pf19422"	"25820"	"ENSG00000166233"	"ARIH1"	"B2R6U3; hsa:25820; O76026; Q9H3T6; Q9UEN0; Q9UP39; Q9Y4X5"	"ISG15 antiviral mechanism"	""	"1"	"0"	"4.0"	"0.0"	"6.9"	"4.1"	"4.1"	"4.7"	"13.6"	"2.4"	"85.1"	"82.5"	"155.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZU35"	"Capping protein inhibiting regulator of actin dynamics OS=Homo sapiens OX=9606 GN=CRACD PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1233"	"136.7"	"5.60"	"431.05"	"2.92"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol"	""	"Pf15262"	"57482"	"ENSG00000109265"	"CRACD"	"hsa:57482; Q6ZU35; Q9NTE2; Q9NTP8; Q9ULK9"	""	""	"0"	"0"	"3.6"	"3.2"	"0.0"	"2.8"	"2.2"	"2.0"	"10.0"	"0.0"	"28.3"	"30.4"	"43.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWJ2"	"GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1684"	"195.8"	"5.14"	"266.59"	"2.91"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf01465, Pf16704"	"9648"	"ENSG00000135968"	"GCC2"	"A6H8X8; hsa:9648; O15045; Q4ZG46; Q8IWJ2; Q8TDH3; Q9H2G8"	"Signaling by ALK fusions and activated point mutants; Retrograde transport at the Trans-Golgi-Network"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00374"	"Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"187"	"21.4"	"7.42"	""	"2.91"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00186"	"1719"	"ENSG00000228716"	"DHFR"	"B4DDD2; hsa:1719; P00374; Q14130; Q6IRW8"	"G1/S-Specific Transcription; Metabolism of folate and pterines; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	"Fluoropyrimidine activity; Folate metabolism; One-carbon metabolism; Retinoblastoma gene in cancer; Trans-sulfuration, one-carbon metabolism and related pathways; Ethanol effects on histone modifications"	"9"	"0"	"19.6"	"9.8"	"21.8"	"12.4"	"11.7"	"15.6"	"31.2"	"0.0"	"356.8"	"359.0"	"826.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPW5"	"Cytosolic carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=AGTPBP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1226"	"138.4"	"6.15"	"294.07"	"2.90"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00246, Pf18027"	"23287"	"ENSG00000135049"	"AGTPBP1"	"B4DIT6; B4DRZ8; hsa:23287; Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6; Q9H9W8; Q9NVK1; Q9UPW5"	"Carboxyterminal post-translational modifications of tubulin"	""	"1"	"0"	"8.3"	"5.3"	"9.7"	"6.8"	"6.1"	"8.9"	"15.4"	"0.0"	"57.6"	"51.6"	"134.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRQ6"	"MICOS complex subunit MIC25 OS=Homo sapiens OX=9606 GN=CHCHD6 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"235"	"26.4"	"8.85"	"262.55"	"2.90"	"1"	"1"	"cell organization and biogenesis;stress response"	"other membranes;cytosol;mitochondrion"	""	"Pf05300"	"84303"	"ENSG00000159685"	"CHCHD6"	"D6R9U0; D6RIB4; H8Y0Y7; hsa:84303; Q9BRQ6"	"Cristae formation"	""	"1"	"0"	"3.5"	"0.0"	"0.0"	"0.0"	"0.0"	"2.1"	"4.0"	"1.5"	"31.0"	"37.6"	"49.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5F1R6"	"DnaJ homolog subfamily C member 21 OS=Homo sapiens OX=9606 GN=DNAJC21 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"531"	"62.0"	"5.47"	"234.63"	"2.90"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf12171"	"134218"	"ENSG00000168724"	"DNAJC21"	"hsa:134218; Q3B7J9; Q5F1R6; Q6P086; Q6ZS43; Q86VC6"	""	""	"0"	"0"	"26.6"	"26.5"	"44.0"	"37.1"	"31.9"	"37.0"	"89.6"	"2.7"	"309.3"	"308.3"	"611.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0V9"	"Septin-10 OS=Homo sapiens OX=9606 GN=SEPTIN10 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"454"	"52.6"	"6.80"	"288.08"	"2.90"	"1"	"1"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"151011"	"ENSG00000186522"	"SEPTIN10"	"B3KRQ9; hsa:151011; Q86VP5; Q9HAH6; Q9P0V9"	""	""	"0"	"0"	"3.0"	"0.0"	"5.9"	"3.2"	"6.4"	"3.5"	"12.6"	"2.6"	"125.9"	"133.6"	"211.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95721"	"Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"258"	"29.0"	"5.81"	"320.99"	"2.89"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"9342"	"ENSG00000099940"	"SNAP29"	"hsa:9342; O95721"	"Neutrophil degranulation; Intra-Golgi traffic"	"Ciliary landscape; 22q11.2 copy number variation syndrome"	"4"	"0"	"4.0"	"7.4"	"4.7"	"4.7"	"5.3"	"6.4"	"28.1"	"1.4"	"80.2"	"72.8"	"139.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86T03"	"Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase OS=Homo sapiens OX=9606 GN=PIP4P1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"277"	"29.5"	"8.91"	"298.52"	"2.89"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf09788"	"90809"	"ENSG00000165782"	"PIP4P1"	"B2RA35; hsa:90809; Q86T03; Q86U09; Q8WUC0; Q9BU67; Q9NSU8"	"PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	""	"2"	"0"	"4.4"	"3.8"	"6.4"	"3.5"	"6.0"	"0.0"	"8.5"	"0.0"	"57.3"	"46.7"	"118.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75487"	"Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"556"	"62.4"	"6.68"	"360.44"	"2.89"	"1"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01153"	"2239"	"ENSG00000076716"	"GPC4"	"B2R6J7; B4E2C0; hsa:2239; O75487; Q6ZMA6; Q96L43; Q9NU08; Q9UJN1; Q9UPD9"	"A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport"	"Wnt signaling"	"11"	"0"	"56.7"	"47.8"	"54.6"	"47.5"	"39.6"	"50.0"	"149.2"	"0.0"	"447.9"	"429.5"	"806.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IV0"	"Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Homo sapiens OX=9606 GN=NGLY1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"654"	"74.3"	"6.89"	"275.98"	"2.89"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01841, Pf04721, Pf09409"	"55768"	"ENSG00000151092"	"NGLY1"	"B4DJE9; hsa:55768; Q59FB1; Q6PJD8; Q96IV0; Q9BVR8; Q9NR70"	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	""	"1"	"0"	"2.8"	"0.0"	"2.3"	"0.0"	"0.0"	"0.0"	"3.5"	"1.5"	"41.9"	"54.0"	"106.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9HD42"	"Charged multivesicular body protein 1a OS=Homo sapiens OX=9606 GN=CHMP1A PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"196"	"21.7"	"8.06"	""	"2.88"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"5119"	"ENSG00000131165"	"CHMP1A"	"A2RU09; hsa:5119; Q14468; Q15779; Q96G31; Q9HD42"	"HCMV Late Events"	""	"1"	"0"	"10.2"	"9.5"	"16.2"	"16.9"	"14.9"	"11.7"	"34.3"	"0.0"	"751.7"	"761.6"	"1377.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15049"	"Membrane protein MLC1 OS=Homo sapiens OX=9606 GN=MLC1 PE=1 SV=5"	"0.000"	""	"4"	"1"	"2"	"1"	"377"	"41.1"	"7.49"	"246.88"	"2.88"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"23209"	"ENSG00000100427"	"MLC1"	"B3KW61; B7Z659; hsa:23209; Q15049; Q5JZ83; Q8TAG4; Q96RP5; Q9UGY8"	""	""	"0"	"0"	"47.2"	"9.8"	"96.6"	"64.3"	"80.8"	"46.2"	"52.8"	"0.0"	"286.7"	"203.5"	"695.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NL6"	"Sodium channel and clathrin linker 1 OS=Homo sapiens OX=9606 GN=SCLT1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"688"	"80.9"	"6.07"	"243.35"	"2.88"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"132320"	"ENSG00000151466"	"SCLT1"	"A4QN04; hsa:132320; Q0VAH2; Q6P2M4; Q96NL6"	"Anchoring of the basal body to the plasma membrane"	"Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5RKV6"	"Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"272"	"28.2"	"6.28"	"597.71"	"2.88"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf01138"	"118460"	"ENSG00000223496"	"EXOSC6"	"hsa:118460; Q5RKV6"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	""	"6"	"0"	"43.0"	"34.7"	"45.4"	"42.3"	"41.8"	"40.7"	"134.0"	"0.0"	"450.1"	"515.4"	"1071.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94811"	"Tubulin polymerization-promoting protein OS=Homo sapiens OX=9606 GN=TPPP PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"219"	"23.7"	"9.44"	"313.29"	"2.88"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05517"	"11076"	"ENSG00000171368"	"TPPP"	"hsa:11076; O94811"	""	"Microtubule cytoskeleton regulation; Glial cell differentiation; Sudden infant death syndrome (SIDS) susceptibility pathways"	"3"	"0"	"1.9"	"0.0"	"6.3"	"1.8"	"0.0"	"0.0"	"6.6"	"0.0"	"57.9"	"72.2"	"73.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UL25"	"Ras-related protein Rab-21 OS=Homo sapiens OX=9606 GN=RAB21 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"225"	"24.3"	"7.94"	"303.78"	"2.87"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"23011"	"ENSG00000080371"	"RAB21"	"hsa:23011; Q14466; Q569H3; Q9UL25"	"RAB GEFs exchange GTP for GDP on RABs; RAB geranylgeranylation"	"Ciliary landscape"	"3"	"0"	"0.0"	"3.9"	"5.5"	"5.0"	"6.6"	"4.6"	"10.5"	"1.4"	"55.6"	"60.2"	"119.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48634"	"Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3"	"0.000"	""	"1"	"2"	"2"	"1"	"2157"	"228.7"	"9.45"	"623.39"	"2.87"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	""	"Pf07001"	"7916"	"ENSG00000204469; ENSG00000206427; ENSG00000225164; ENSG00000225748; ENSG00000226618; ENSG00000231370; ENSG00000231825"	"PRRC2A"	"B0UX77; B0UZE9; B0UZL3; hsa:7916; O95875; P48634; Q05BK4; Q4LE37; Q5SQ29; Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9; Q96QC6"	""	""	"0"	"0"	"43.8"	"63.9"	"35.7"	"33.4"	"31.8"	"46.7"	"270.4"	"0.0"	"469.4"	"409.4"	"643.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZ32"	"Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"417"	"46.3"	"7.37"	"325.25"	"2.87"	"1"	"1"	"transport"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	""	"Pf00022"	"55860"	"ENSG00000131966"	"ACTR10"	"hsa:55860; Q9H9Y5; Q9NWY2; Q9NZ32"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Neutrophil degranulation"	""	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3SYG4"	"Protein PTHB1 OS=Homo sapiens OX=9606 GN=BBS9 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"887"	"99.2"	"5.55"	"300.31"	"2.87"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf14727, Pf14728"	"27241"	"ENSG00000122507"	"BBS9"	"E9PDC9; hsa:27241; P78514; Q3SYG4; Q7KYS6; Q7KYS7; Q8N570; Q99844; Q99854; Q9Y699; Q9Y6A0"	"BBSome-mediated cargo-targeting to cilium"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"6"	"0"	"9.9"	"5.7"	"12.9"	"9.9"	"7.7"	"9.6"	"19.2"	"1.6"	"224.4"	"201.0"	"351.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P0CG22"	"Putative dehydrogenase/reductase SDR family member 4-like 1 OS=Homo sapiens OX=9606 GN=DHRS4L1 PE=5 SV=1"	""	""	"5"	"1"	"1"	"1"	"281"	"30.6"	"9.77"	""	"2.86"	""	"1"	"other metabolic processes"	"other cytoplasmic organelle"	"other molecular function"	"Pf13561"	""	""	"DHRS4L1"	"P0CG22"	""	""	"0"	"0"	"32.7"	"65.1"	"24.1"	"33.8"	"23.8"	"49.7"	"119.9"	"0.0"	"970.3"	"913.3"	"1449.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96P47"	"Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3 OS=Homo sapiens OX=9606 GN=AGAP3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"875"	"95.0"	"7.97"	"368.81"	"2.86"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf01412, Pf12796"	"116988"	"ENSG00000133612"	"AGAP3"	"B3KNZ8; E9PAL8; hsa:116988; Q59EN0; Q96P47; Q96RK3"	""	""	"0"	"0"	"22.2"	"21.7"	"30.4"	"23.3"	"30.2"	"29.1"	"111.8"	"0.0"	"777.3"	"725.7"	"1125.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82663"	"28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"173"	"20.1"	"8.82"	"274.88"	"2.86"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"64432"	"ENSG00000131368"	"MRPS25"	"B4DFJ5; B4DQG6; hsa:64432; P82663; Q9H7P5"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULT0"	"Tetratricopeptide repeat protein 7A OS=Homo sapiens OX=9606 GN=TTC7A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"858"	"96.1"	"6.46"	"301.53"	"2.86"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf13181, Pf19440"	"57217"	"ENSG00000068724"	"TTC7A"	"hsa:57217; Q2T9J9; Q6PIX4; Q8ND67; Q9BUS3; Q9ULT0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H7D7"	"WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"661"	"72.1"	"6.16"	""	"2.85"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf00400, Pf17814"	"80232"	"ENSG00000162923"	"WDR26"	"A0MNN3; hsa:80232; Q4G100; Q59EC4; Q5GLZ9; Q86UY4; Q9H3C2; Q9H7D7"	""	"Ciliary landscape"	"1"	"0"	"11.5"	"5.7"	"7.7"	"7.6"	"8.8"	"3.3"	"9.7"	"0.0"	"69.8"	"59.0"	"126.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75347"	"Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"108"	"12.8"	"5.29"	"372.74"	"2.85"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02970"	"6902"	"ENSG00000171530"	"TBCA"	"B4DT30; hsa:6902; O75347"	"Post-chaperonin tubulin folding pathway"	"VEGFA-VEGFR2 signaling"	"2"	"0"	"6.5"	"4.9"	"6.6"	"5.8"	"4.8"	"0.0"	"11.2"	"0.0"	"40.1"	"43.5"	"118.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CZ1"	"Protein fantom OS=Homo sapiens OX=9606 GN=RPGRIP1L PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1315"	"151.1"	"5.35"	"248.16"	"2.85"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding"	"Pf00168, Pf11618, Pf18111"	"23322"	"ENSG00000103494"	"RPGRIP1L"	"A0PJ88; hsa:23322; Q68CZ1; Q9Y2K8"	"Anchoring of the basal body to the plasma membrane; Hedgehog 'off' state"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; NPHP1 deletion syndrome"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYI6"	"Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"725"	"81.7"	"5.49"	"299.21"	"2.85"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf08700, Pf16528"	"149371"	"ENSG00000116903"	"EXOC8"	"B3KU33; hsa:149371; Q5TE82; Q8IYI6"	"Insulin processing; Translocation of SLC2A4 (GLUT4) to the plasma membrane; VxPx cargo-targeting to cilium"	"RalA downstream regulated genes; Ciliary landscape"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33981"	"Dual specificity protein kinase TTK OS=Homo sapiens OX=9606 GN=TTK PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"857"	"97.0"	"8.16"	"488.84"	"2.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"7272"	"ENSG00000112742"	"TTK"	"A8K8U5; B2RDW2; E1P543; hsa:7272; P33981; Q15272; Q5TCS0; Q9BW51; Q9NTM0"	""	"Cell cycle; Retinoblastoma gene in cancer"	"2"	"0"	"6.9"	"2.5"	"10.5"	"7.3"	"10.9"	"8.6"	"14.3"	"0.4"	"148.2"	"158.3"	"349.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07237"	"Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"508"	"57.1"	"4.87"	"249.39"	"2.84"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00085, Pf13848"	"5034"	"ENSG00000185624"	"P4HB"	"B2RDQ2; hsa:5034; P07237; P30037; P32079; Q15205; Q6LDE5"	"Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes; Detoxification of Reactive Oxygen Species; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Insulin processing; Interleukin-12 signaling; Interleukin-23 signaling; Chylomicron assembly; VLDL assembly; LDL remodeling"	"VEGFA-VEGFR2 signaling; Type I collagen synthesis in the context of osteogenesis imperfecta"	"13"	"0"	"21.8"	"13.8"	"25.6"	"23.3"	"24.4"	"17.7"	"36.6"	"0.0"	"104.7"	"115.8"	"173.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y221"	"60S ribosome subunit biogenesis protein NIP7 homolog OS=Homo sapiens OX=9606 GN=NIP7 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"180"	"20.4"	"8.51"	""	"2.84"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf03657, Pf17833"	"51388"	"ENSG00000132603"	"NIP7"	"B2RD04; hsa:51388; Q9NZZ0; Q9Y221"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.9"	"1.8"	"51.9"	"54.7"	"149.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30622"	"CAP-Gly domain-containing linker protein 1 OS=Homo sapiens OX=9606 GN=CLIP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1438"	"162.1"	"5.36"	"311.14"	"2.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf16641"	"6249"	"ENSG00000130779"	"CLIP1"	"A0AVD3; hsa:6249; P30622; Q17RS4; Q29RG0"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Microtubule cytoskeleton regulation; PAFAH1B1 copy number variation"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96GA3"	"Protein LTV1 homolog OS=Homo sapiens OX=9606 GN=LTV1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"475"	"54.8"	"4.91"	""	"2.84"	""	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04180"	"84946"	"ENSG00000135521"	"LTV1"	"hsa:84946; Q96GA3; Q96JX8"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"28.3"	"27.9"	"22.3"	"23.9"	"25.2"	"17.9"	"57.3"	"0.0"	"303.7"	"329.4"	"534.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUW8"	"Tyrosyl-DNA phosphodiesterase 1 OS=Homo sapiens OX=9606 GN=TDP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"608"	"68.4"	"7.65"	"288.66"	"2.84"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06087"	"55775"	"ENSG00000042088"	"TDP1"	"hsa:55775; Q2HXX4; Q86TV8; Q96BK7; Q9NUW8; Q9NZM7; Q9NZM8"	"Nonhomologous End-Joining (NHEJ)"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95433"	"Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"338"	"38.3"	"5.53"	""	"2.83"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf08327, Pf09229"	"10598"	"ENSG00000100591"	"AHSA1"	"B2R9L2; B4DUR9; hsa:10598; O95433; Q96IL6; Q9P060"	""	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.1"	"5.2"	"55.0"	"53.4"	"127.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JC1"	"Vam6/Vps39-like protein OS=Homo sapiens OX=9606 GN=VPS39 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"886"	"101.7"	"6.99"	"320.77"	"2.83"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	""	"Pf00780, Pf10366, Pf10367"	"23339"	"ENSG00000166887"	"VPS39"	"hsa:23339; O94869; Q71SQ6; Q7Z3V3; Q96B93; Q96JC1; Q96RM0"	"SARS-CoV-2 modulates autophagy"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DE0"	"U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"195"	"21.3"	"6.89"	"304.11"	"2.83"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"131870"	"ENSG00000198585"	"NUDT16"	"B4E3B4; E9PED4; F5GYJ1; hsa:131870; Q96DE0; Q96N82"	"Phosphate bond hydrolysis by NUDT proteins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZM8"	"Nuclear distribution protein nudE-like 1 OS=Homo sapiens OX=9606 GN=NDEL1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"345"	"38.4"	"5.24"	"259.18"	"2.82"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04880"	"81565"	"ENSG00000166579"	"NDEL1"	"B3KP93; D3DTS0; hsa:81565; J3QT32; Q86T80; Q8TAR7; Q9GZM8; Q9UH50"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Neurogenesis regulation in the olfactory epithelium; PAFAH1B1 copy number variation"	"8"	"0"	"9.0"	"11.1"	"12.8"	"10.8"	"10.9"	"7.2"	"18.3"	"1.1"	"194.7"	"205.1"	"348.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTL3"	"RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"118"	"14.4"	"8.94"	"269.10"	"2.82"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf15320"	"83640"	"ENSG00000169612"	"RAMAC"	"hsa:83640; Q2M1J8; Q9BTL3"	""	"15q25 copy number variation"	"1"	"0"	"106.4"	"76.6"	"108.1"	"92.8"	"89.0"	"90.8"	"153.8"	"0.0"	"528.3"	"465.1"	"990.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52747"	"Zinc finger protein 143 OS=Homo sapiens OX=9606 GN=ZNF143 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"638"	"68.9"	"6.05"	"346.46"	"2.82"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7702"	"ENSG00000166478"	"ZNF143"	"A8K518; B4DLY5; E7ER34; hsa:7702; O75559; P52747; Q8WUK9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA polymerase II transcribes snRNA genes"	"IL-18 signaling pathway"	"4"	"0"	"47.2"	"46.4"	"34.4"	"38.1"	"43.1"	"44.6"	"114.5"	"0.0"	"397.4"	"429.6"	"754.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T440"	"Putative transferase CAF17, mitochondrial OS=Homo sapiens OX=9606 GN=IBA57 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"356"	"38.1"	"9.83"	"240.03"	"2.81"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion"	"other molecular function"	""	"200205"	"ENSG00000181873"	"IBA57"	"hsa:200205; Q5T440"	""	""	"0"	"0"	"41.2"	"28.9"	"47.7"	"32.8"	"42.8"	"46.3"	"66.8"	"0.6"	"404.9"	"390.7"	"711.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92905"	"COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"334"	"37.6"	"6.54"	"339.54"	"2.81"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf18323"	"10987"	"ENSG00000121022"	"COPS5"	"hsa:10987; O15386; Q6AW95; Q86WQ4; Q92905; Q9BQ17"	"Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; Neddylation; DNA Damage Recognition in GG-NER"	""	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.4"	"0.0"	"39.2"	"30.2"	"105.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95429"	"BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"457"	"49.6"	"5.12"	"312.69"	"2.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf02179"	"9530"	"ENSG00000156735"	"BAG4"	"B4E217; hsa:9530; O95429; O95818"	"Signaling by FGFR1 in disease; Regulation of HSF1-mediated heat shock response; Signaling by plasma membrane FGFR1 fusions; TNF signaling"	"Oxidative damage response"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTE3"	"Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"642"	"72.9"	"5.87"	"323.57"	"2.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09739"	"79892"	"ENSG00000197771"	"MCMBP"	"B3KSP7; hsa:79892; Q6IA56; Q9BTE3; Q9BVT9; Q9H916"	""	""	"0"	"0"	"31.6"	"28.8"	"19.6"	"21.5"	"21.5"	"23.7"	"51.8"	"0.0"	"304.9"	"300.2"	"448.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00217"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"210"	"23.7"	"6.34"	"312.34"	"2.80"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf12838"	"4728"	"ENSG00000110717"	"NDUFS8"	"B2RB86; hsa:4728; O00217; Q0VDA8"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"3.3"	"4.0"	"5.9"	"3.5"	"3.5"	"8.9"	"9.7"	"0.4"	"126.7"	"147.0"	"365.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUA3"	"Spindlin interactor and repressor of chromatin-binding protein OS=Homo sapiens OX=9606 GN=SPINDOC PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"381"	"41.0"	"5.01"	"329.91"	"2.79"	"1"	"1"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf18658"	"144097"	"ENSG00000168005"	"SPINDOC"	"hsa:144097; Q68CV7; Q6PHS2; Q96IH0; Q9BUA3"	""	""	"0"	"0"	"17.0"	"13.9"	"24.0"	"19.0"	"16.9"	"21.3"	"37.4"	"0.0"	"318.2"	"369.3"	"667.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3D7"	"Mitochondrial import inner membrane translocase subunit TIM16 OS=Homo sapiens OX=9606 GN=PAM16 PE=1 SV=2"	"0.000"	""	"9"	"1"	"2"	"1"	"125"	"13.8"	"9.70"	"247.00"	"2.79"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	""	"Pf03656"	"51025"	"ENSG00000217930; ENSG00000282228"	"PAM16"	"hsa:51025; Q6I9Z3; Q9H5X3; Q9Y3D7"	"Mitochondrial protein import"	""	"1"	"0"	"9.8"	"10.5"	"10.0"	"9.6"	"8.3"	"8.4"	"19.6"	"0.0"	"110.1"	"113.0"	"187.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42025"	"Beta-centractin OS=Homo sapiens OX=9606 GN=ACTR1B PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"376"	"42.3"	"6.40"	"344.66"	"2.79"	"1"	"1"	""	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"10120"	"ENSG00000115073"	"ACTR1B"	"D3DVH2; hsa:10120; P42025; Q53SK5; Q9BRB7"	"Neutrophil degranulation; MHC class II antigen presentation"	""	"2"	"0"	"36.9"	"31.0"	"40.3"	"35.5"	"41.2"	"32.1"	"53.7"	"0.0"	"395.1"	"415.3"	"879.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9ULM3"	"YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1422"	"150.7"	"8.98"	""	"2.78"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03366"	"55689"	"ENSG00000163872"	"YEATS2"	"A7E2B9; D3DNS9; hsa:55689; Q641P6; Q9NW96; Q9ULM3"	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51649"	"Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"535"	"57.2"	"8.28"	"370.25"	"2.78"	"1"	"1"	"other metabolic processes;developmental processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"7915"	"ENSG00000112294"	"ALDH5A1"	"B2RD26; G5E949; hsa:7915; P51649; Q546H9; Q8N3W6"	"Degradation of GABA"	"Fragile X syndrome"	"2"	"0"	"8.0"	"5.6"	"10.7"	"5.7"	"6.3"	"4.7"	"10.4"	"0.0"	"85.8"	"92.0"	"250.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15417"	"Calponin-3 OS=Homo sapiens OX=9606 GN=CNN3 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"329"	"36.4"	"6.05"	""	"2.78"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00402"	"1266"	"ENSG00000117519"	"CNN3"	"B4DFK6; B4DP09; F8WA86; hsa:1266; Q15417; Q6FHA7"	""	""	"0"	"0"	"7.6"	"5.4"	"13.2"	"9.7"	"8.1"	"9.2"	"18.1"	"0.0"	"320.3"	"310.9"	"892.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BX10"	"GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GTPBP2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"602"	"65.7"	"8.05"	"329.83"	"2.77"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"54676"	"ENSG00000172432"	"GTPBP2"	"hsa:54676; Q5T7E8; Q8ND84; Q8TAH7; Q8WUA5; Q9BX10; Q9HCS9; Q9NRU4; Q9NX60"	"Platelet degranulation"	"Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway"	"2"	"0"	"7.4"	"4.4"	"4.0"	"5.7"	"3.5"	"6.6"	"15.4"	"0.0"	"106.9"	"131.5"	"277.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULV3"	"Cip1-interacting zinc finger protein OS=Homo sapiens OX=9606 GN=CIZ1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"898"	"100.0"	"6.11"	"307.00"	"2.77"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"25792"	"ENSG00000148337"	"CIZ1"	"A8K9J8; B4E131; B7ZAS8; hsa:25792; Q5SYW3; Q5SYW5; Q8WU72; Q9H868; Q9NYM8; Q9UHK4; Q9ULV3; Q9Y3F9; Q9Y3G0"	""	""	"0"	"0"	"12.4"	"5.8"	"11.2"	"13.5"	"13.7"	"16.7"	"29.4"	"2.3"	"71.6"	"71.0"	"120.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92896"	"Golgi apparatus protein 1 OS=Homo sapiens OX=9606 GN=GLG1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1179"	"134.5"	"6.90"	"331.59"	"2.77"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytoskeleton;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf00839"	"2734"	"ENSG00000090863"	"GLG1"	"B7Z8Y4; D3DUJ7; hsa:2734; Q13221; Q6P9D1; Q92896"	"Cell surface interactions at the vascular wall"	""	"1"	"0"	"15.0"	"12.9"	"15.6"	"14.0"	"16.8"	"17.4"	"24.3"	"1.5"	"353.7"	"310.5"	"676.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78559"	"Microtubule-associated protein 1A OS=Homo sapiens OX=9606 GN=MAP1A PE=1 SV=6"	"0.000"	""	"1"	"2"	"2"	"1"	"2803"	"305.3"	"4.92"	"235.51"	"2.77"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4130"	"ENSG00000166963"	"MAP1A"	"hsa:4130; O95643; P78559; Q12973; Q15882; Q9UJT4"	""	""	"0"	"1"	"12.5"	"6.0"	"14.1"	"13.3"	"18.9"	"23.6"	"39.4"	"0.9"	"240.2"	"232.8"	"453.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NUQ4"	"Transmembrane protein 214 OS=Homo sapiens OX=9606 GN=TMEM214 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"689"	"77.1"	"9.14"	"331.77"	"2.77"	"1"	"1"	"other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi"	""	"Pf10151"	"54867"	"ENSG00000119777"	"TMEM214"	"A6NNF2; B3KUI9; B5MCD8; D6W547; hsa:54867; Q53SW1; Q69YH4; Q6NUQ4; Q8NC45; Q8WZ37; Q9NXH2"	""	""	"0"	"0"	"73.3"	"46.8"	"96.6"	"87.5"	"77.6"	"59.3"	"200.9"	"0.0"	"367.0"	"281.4"	"783.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46459"	"Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"744"	"82.5"	"6.95"	"546.58"	"2.76"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf17862"	"4905"	"ENSG00000073969; ENSG00000276262; ENSG00000278174"	"NSF"	"A8K2D9; B4DFA2; hsa:4905; P46459; Q8N6D7; Q9UKZ2"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Intra-Golgi traffic; COPII-mediated vesicle transport; Retrograde transport at the Trans-Golgi-Network; Trafficking of GluR2-containing AMPA receptors"	"Synaptic vesicle pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"8"	"0"	"6.1"	"2.4"	"5.1"	"5.1"	"6.1"	"5.2"	"10.6"	"0.0"	"88.9"	"103.2"	"189.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXR7"	"BRISC and BRCA1-A complex member 2 OS=Homo sapiens OX=9606 GN=BABAM2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"383"	"43.5"	"5.81"	"318.46"	"2.76"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf06113"	"9577"	"ENSG00000158019"	"BABAM2"	"A8K4X1; D6W562; D6W563; hsa:9577; Q13880; Q4ZFX8; Q53SD0; Q969X9; Q96P06; Q9NXR7"	"Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Metalloprotease DUBs; Nonhomologous End-Joining (NHEJ)"	"5q35 copy number variation"	"6"	"0"	"23.7"	"12.8"	"22.8"	"25.3"	"23.0"	"16.5"	"37.2"	"2.2"	"367.7"	"354.6"	"730.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P23470"	"Receptor-type tyrosine-protein phosphatase gamma OS=Homo sapiens OX=9606 GN=PTPRG PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1445"	"161.9"	"6.42"	""	"2.76"	""	"1"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00041, Pf00102, Pf00194"	"5793"	"ENSG00000144724"	"PTPRG"	"B2RU12; B7ZLX5; hsa:5793; P23470; Q15623; Q59EE0; Q68DU5"	""	""	"0"	"0"	"0.0"	"0.0"	"3.1"	"0.0"	"0.0"	"0.0"	"0.0"	"1.9"	"49.9"	"48.4"	"194.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P2R3"	"Rabankyrin-5 OS=Homo sapiens OX=9606 GN=ANKFY1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1169"	"128.3"	"6.10"	""	"2.76"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00023, Pf00651, Pf01363, Pf12796, Pf13637, Pf13857"	"51479"	"ENSG00000185722"	"ANKFY1"	"A8KA65; hsa:51479; Q5RKV4; Q9P2R3; Q9ULG5"	"RHOD GTPase cycle"	""	"1"	"0"	"0.0"	"0.0"	"5.5"	"3.2"	"4.1"	"0.0"	"4.1"	"2.7"	"41.6"	"39.0"	"110.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26640"	"Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4"	"0.000"	""	"2"	"2"	"3"	"2"	"1264"	"140.4"	"7.59"	"916.33"	"2.75"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00043, Pf00133, Pf08264"	"7407"	"ENSG00000096171; ENSG00000204394; ENSG00000224264; ENSG00000226589; ENSG00000231116"	"VARS1"	"B0V1N1; B4DZ61; hsa:7407; P26640; Q5JQ90; Q96E77; Q9UQM2"	"Cytosolic tRNA aminoacylation"	"Amino acid metabolism"	"2"	"0"	"65.3"	"45.8"	"68.1"	"56.5"	"52.4"	"58.3"	"87.7"	"0.0"	"989.6"	"976.7"	"1854.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A0A087WV53"	"SPEG neighbor protein OS=Homo sapiens OX=9606 GN=SPEGNB PE=4 SV=1"	""	""	"7"	"1"	"1"	"1"	"238"	"26.1"	"5.60"	""	"2.75"	""	"1"	""	""	""	"Pf00612, Pf07679"	"100996693"	"ENSG00000286095"	"SPEGNB"	"A0A087WV53; hsa:100996693"	""	""	"0"	"0"	"0.0"	"3.0"	"3.5"	"0.0"	"2.7"	"3.0"	"2.8"	"0.0"	"129.9"	"118.6"	"306.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P035"	"Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"362"	"43.1"	"8.94"	""	"2.75"	""	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04387"	"51495"	"ENSG00000074696"	"HACD3"	"A0PJA1; B4DRF4; hsa:51495; Q280Z3; Q6PD63; Q8IUI5; Q8NC86; Q8NCB1; Q96T12; Q9NQA7; Q9P035"	"Synthesis of very long-chain fatty acyl-CoAs"	""	"1"	"0"	"22.8"	"14.4"	"24.7"	"19.5"	"25.3"	"22.6"	"50.6"	"0.0"	"398.9"	"411.1"	"886.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IQ23"	"Pleckstrin homology domain-containing family A member 7 OS=Homo sapiens OX=9606 GN=PLEKHA7 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1121"	"127.1"	"9.35"	"308.80"	"2.74"	"1"	"1"	"cell adhesion;cell organization and biogenesis"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00169"	"144100"	"ENSG00000166689"	"PLEKHA7"	"B4DK33; B4DWC3; hsa:144100; Q6IQ23; Q86VZ7"	""	""	"0"	"0"	"23.7"	"23.0"	"30.9"	"24.7"	"29.7"	"28.4"	"55.0"	"0.0"	"265.1"	"294.6"	"467.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12857"	"Nuclear factor 1 A-type OS=Homo sapiens OX=9606 GN=NFIA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"509"	"55.9"	"8.44"	"289.20"	"2.74"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00859, Pf03165, Pf10524"	"4774"	"ENSG00000162599"	"NFIA"	"B4DRJ3; B4DS53; F5H0R0; F8W8W3; hsa:4774; Q12857; Q8TA97; Q9H3X9; Q9P2A9"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2W9"	"Syntaxin-18 OS=Homo sapiens OX=9606 GN=STX18 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"335"	"38.7"	"5.49"	"553.23"	"2.74"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf10496"	"53407"	"ENSG00000168818"	"STX18"	"hsa:53407; Q596L3; Q5TZP5; Q9P2W9"	"COPI-dependent Golgi-to-ER retrograde traffic"	""	"1"	"0"	"7.7"	"1.9"	"12.3"	"6.5"	"10.7"	"9.8"	"15.3"	"1.8"	"72.7"	"74.0"	"152.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y623"	"Myosin-4 OS=Homo sapiens OX=9606 GN=MYH4 PE=2 SV=2"	"0.000"	""	"1"	"2"	"2"	"1"	"1939"	"222.9"	"5.85"	"225.26"	"2.74"	"1"	"1"	"other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4622"	"ENSG00000264424"	"MYH4"	"hsa:4622; Q9Y623"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IV48"	"3'-5' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=ERI1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"349"	"40.0"	"6.70"	""	"2.73"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00929, Pf02037"	"90459"	"ENSG00000104626"	"ERI1"	"A8K4U7; hsa:90459; Q8IV48; Q9NSX3"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"exRNA mechanism of action and biogenesis; 8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"4"	"0"	"15.0"	"13.1"	"23.6"	"16.5"	"22.4"	"14.7"	"43.9"	"7.9"	"661.1"	"662.9"	"1331.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96DV4"	"39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"380"	"44.6"	"7.53"	""	"2.73"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf01161"	"64978"	"ENSG00000204316"	"MRPL38"	"B3KN96; hsa:64978; Q96DV4; Q96Q66; Q9P0B9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"19.7"	"18.5"	"22.3"	"19.4"	"18.7"	"14.1"	"51.9"	"0.0"	"194.5"	"206.5"	"707.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51116"	"Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"1"	"673"	"74.2"	"6.23"	"1033.34"	"2.73"	"2"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf17904, Pf18336"	"9513"	"ENSG00000129245"	"FXR2"	"B2R9M2; D3DTQ1; hsa:9513; P51116; Q86V09; Q8WUM2"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"13.3"	"11.6"	"14.1"	"14.2"	"13.4"	"5.9"	"46.2"	"3.2"	"148.2"	"138.9"	"266.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51114"	"Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"1"	"621"	"69.7"	"6.15"	"973.56"	"2.73"	"2"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf16097, Pf17904, Pf18336"	"8087"	"ENSG00000114416"	"FXR1"	"A8K9B8; hsa:8087; P51114; Q7Z450; Q8N6R8"	"Signaling by BRAF and RAF1 fusions"	"Bile acids synthesis and enterohepatic circulation"	"2"	"0"	"6.3"	"4.7"	"8.2"	"4.5"	"5.9"	"6.6"	"22.6"	"1.1"	"149.1"	"143.1"	"253.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969E8"	"Pre-rRNA-processing protein TSR2 homolog OS=Homo sapiens OX=9606 GN=TSR2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"191"	"20.9"	"4.39"	"286.59"	"2.73"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10273"	"90121"	"ENSG00000158526"	"TSR2"	"hsa:90121; Q969E8"	""	""	"0"	"0"	"91.2"	"68.3"	"81.0"	"73.9"	"70.3"	"50.9"	"113.0"	"0.0"	"456.3"	"454.1"	"711.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8K855"	"EF-hand calcium-binding domain-containing protein 7 OS=Homo sapiens OX=9606 GN=EFCAB7 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"629"	"71.9"	"6.38"	"357.50"	"2.72"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	""	"84455"	"ENSG00000203965"	"EFCAB7"	"A8K855; hsa:84455; Q658P0; Q96B95; Q96JM6"	"Activation of SMO"	"Genes related to primary cilium development (based on CRISPR)"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43865"	"S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"530"	"58.9"	"6.89"	"336.73"	"2.72"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00670, Pf05221"	"10768"	"ENSG00000168710"	"AHCYL1"	"B4E168; hsa:10768; O43865; Q2TAJ6; Q502W8; Q5VSM0; Q6P171; Q96PK4; Q9UG84"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Regulation of insulin secretion; VEGFR2 mediated cell proliferation; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation"	"Trans-sulfuration, one-carbon metabolism and related pathways"	"11"	"0"	"80.3"	"59.7"	"66.4"	"63.0"	"56.9"	"39.6"	"108.3"	"9.5"	"465.1"	"455.4"	"803.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5A9"	"YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"579"	"62.3"	"8.79"	"515.32"	"2.72"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04146"	"51441"	"ENSG00000198492"	"YTHDF2"	"A6NKG4; A8K966; B4E1G7; D3DPM8; hsa:51441; Q5VSZ9; Q8TDH0; Q9BUJ5; Q9Y5A9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z739"	"YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"1"	"585"	"63.8"	"9.04"	"514.65"	"2.72"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity"	"Pf04146"	"253943"	"ENSG00000185728"	"YTHDF3"	"B3KXL4; hsa:253943; Q63Z37; Q659A3; Q7Z739"	""	""	"0"	"1"	"215.5"	"158.5"	"173.6"	"167.8"	"158.7"	"160.2"	"318.2"	"0.0"	"1371.7"	"1407.8"	"2820.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26885"	"Peptidyl-prolyl cis-trans isomerase FKBP2 OS=Homo sapiens OX=9606 GN=FKBP2 PE=1 SV=2"	"0.000"	""	"13"	"2"	"3"	"2"	"142"	"15.6"	"9.13"	"640.63"	"2.72"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00254"	"2286"	"ENSG00000173486"	"FKBP2"	"hsa:2286; P26885; Q5BJH9; Q9BTS7"	""	"Complement system"	"1"	"0"	"56.5"	"52.8"	"66.9"	"62.7"	"58.7"	"68.4"	"84.8"	"0.0"	"1512.0"	"1559.3"	"2290.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9T3"	"Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"547"	"62.2"	"8.88"	"355.16"	"2.72"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00583, Pf04055, Pf16199"	"55140"	"ENSG00000134014"	"ELP3"	"B4DE19; B4DIG1; E2QRI5; hsa:55140; Q53G84; Q6AWB0; Q9BVF7; Q9H9T3; Q9NVZ1"	"HATs acetylate histones"	"Ethanol effects on histone modifications"	"2"	"0"	"19.2"	"12.3"	"12.0"	"9.5"	"13.4"	"8.4"	"13.0"	"0.0"	"166.5"	"170.6"	"455.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4P3"	"Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"447"	"49.8"	"9.44"	"237.37"	"2.71"	"1"	"1"	"stress response;signal transduction"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00400"	"26608"	"ENSG00000106638"	"TBL2"	"hsa:26608; Q9UQE2; Q9Y4P3"	""	"7q11.23 copy number variation syndrome"	"1"	"0"	"0.0"	"0.0"	"5.4"	"3.9"	"5.0"	"5.7"	"6.6"	"1.1"	"46.1"	"46.5"	"84.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GG9"	"DCN1-like protein 1 OS=Homo sapiens OX=9606 GN=DCUN1D1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"259"	"30.1"	"5.34"	"249.19"	"2.71"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03556, Pf14555"	"54165"	"ENSG00000043093"	"DCUN1D1"	"B2RB37; hsa:54165; Q7L3G9; Q8TEX7; Q96GG9; Q9H6M1; Q9HCT3"	"Neddylation"	""	"1"	"0"	"6.3"	"3.4"	"5.8"	"4.1"	"5.7"	"7.4"	"5.5"	"0.0"	"117.8"	"106.4"	"268.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N8R7"	"ARL14 effector protein OS=Homo sapiens OX=9606 GN=ARL14EP PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"260"	"29.3"	"8.07"	"346.61"	"2.71"	"1"	"1"	""	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf14949"	"120534"	"ENSG00000152219"	"ARL14EP"	"hsa:120534; Q5HYH9; Q8N8R7"	""	""	"0"	"0"	"17.4"	"8.6"	"13.8"	"12.5"	"15.0"	"14.1"	"31.1"	"0.0"	"299.4"	"315.3"	"638.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75874"	"Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"414"	"46.6"	"7.01"	""	"2.71"	""	"1"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00180"	"3417"	"ENSG00000138413"	"IDH1"	"hsa:3417; O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8"	"Peroxisomal protein import; Neutrophil degranulation; Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate; NADPH regeneration; NFE2L2 regulating TCA cycle genes"	"Glutathione metabolism; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism"	"8"	"0"	"37.2"	"18.2"	"50.1"	"32.9"	"31.4"	"38.4"	"64.6"	"0.0"	"418.9"	"430.2"	"1127.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NPA8"	"Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"101"	"11.5"	"9.33"	""	"2.71"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf10163"	"56943"	"ENSG00000120533"	"ENY2"	"B2RE52; G3V117; hsa:56943; Q9NPA8"	"HATs acetylate histones"	""	"1"	"0"	"12.7"	"11.3"	"19.2"	"17.4"	"18.9"	"16.6"	"34.4"	"0.0"	"283.3"	"295.9"	"627.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H270"	"Vacuolar protein sorting-associated protein 11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"941"	"107.8"	"7.05"	"291.43"	"2.71"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00637, Pf12451, Pf13923"	"55823"	""	"VPS11"	"hsa:55823; Q8WY89; Q96EP8; Q9H270; Q9H6D9; Q9HCS6"	"SARS-CoV-2 modulates autophagy"	"Network map of SARS-CoV-2 signaling pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15075"	"Serine/threonine-protein kinase DCLK1 OS=Homo sapiens OX=9606 GN=DCLK1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"740"	"82.2"	"8.66"	"442.50"	"2.70"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf03607"	"9201"	"ENSG00000133083"	"DCLK1"	"B7Z3E9; hsa:9201; O15075; Q5VZY8; Q5VZZ0; Q5VZZ1"	""	"Orexin receptor pathway"	"1"	"0"	"7.6"	"9.0"	"11.6"	"8.4"	"5.7"	"7.3"	"18.8"	"0.0"	"82.0"	"85.9"	"182.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZN8"	"CCR4-NOT transcription complex subunit 2 OS=Homo sapiens OX=9606 GN=CNOT2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"540"	"59.7"	"7.66"	"345.54"	"2.70"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04153"	"4848"	"ENSG00000111596"	"CNOT2"	"hsa:4848; Q9H3E0; Q9NSX5; Q9NWR6; Q9NZN8; Q9P028"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50402"	"Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"254"	"29.0"	"5.50"	"315.97"	"2.70"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity"	"Pf03020"	"2010"	"ENSG00000102119"	"EMD"	"hsa:2010; P50402; Q6FI02"	"RAC1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"Arrhythmogenic right ventricular cardiomyopathy; Envelope proteins and their potential roles in EDMD physiopathology; Influence of laminopathies on Wnt signaling"	"12"	"0"	"64.1"	"40.4"	"42.9"	"47.2"	"40.7"	"52.6"	"85.8"	"2.4"	"467.1"	"422.0"	"965.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55039"	"Developmentally-regulated GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=DRG2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"364"	"40.7"	"8.88"	"231.00"	"2.69"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"1819"	"ENSG00000108591"	"DRG2"	"B2R8G5; hsa:1819; P55039; Q53Y50; Q9BWB2"	""	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"1"	"0"	"3.7"	"2.4"	"0.0"	"0.0"	"2.1"	"1.9"	"4.2"	"0.8"	"43.6"	"49.6"	"88.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15545"	"Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"349"	"40.2"	"5.20"	""	"2.69"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04658"	"6879"	"ENSG00000178913"	"TAF7"	"B2RBV9; hsa:6879; Q13036; Q15545"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"Eukaryotic transcription initiation"	"10"	"0"	"5.8"	"6.1"	"10.5"	"9.4"	"4.2"	"9.1"	"23.1"	"3.1"	"142.1"	"134.2"	"306.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZL9"	"Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"334"	"37.5"	"7.36"	"405.06"	"2.69"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04321"	"27430"	"ENSG00000038274"	"MAT2B"	"B2R5Y6; hsa:27430; Q1WAI7; Q27J92; Q3LIE8; Q567T7; Q6NYC7; Q9BS89; Q9H3E1; Q9NZL9; Q9UJ54"	"Ub-specific processing proteases; Methylation"	"Trans-sulfuration pathway; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"7"	"0"	"20.8"	"18.0"	"19.2"	"18.3"	"16.0"	"17.1"	"20.8"	"0.0"	"171.7"	"142.8"	"338.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY07"	"Electrogenic sodium bicarbonate cotransporter 4 OS=Homo sapiens OX=9606 GN=SLC4A5 PE=2 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1137"	"126.2"	"7.91"	"266.70"	"2.69"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes"	"transporter activity"	"Pf00955, Pf07565"	"57835"	"ENSG00000188687"	"SLC4A5"	"hsa:57835; Q32MA7; Q59EQ9; Q8WXD3; Q8WXD7; Q96DS7; Q96DS8; Q9BY07; Q9HBU5"	"Bicarbonate transporters"	""	"1"	"0"	"7.5"	"0.0"	"5.3"	"6.1"	"4.2"	"8.0"	"18.3"	"7.6"	"769.1"	"766.9"	"1978.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P09669"	"Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2"	""	""	"11"	"1"	"1"	"1"	"75"	"8.8"	"10.39"	""	"2.68"	""	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	"Pf02937"	"1345"	"ENSG00000164919"	"COX6C"	"B2R4D7; hsa:1345; P09669"	"TP53 Regulates Metabolic Genes; Respiratory electron transport; Cytoprotection by HMOX1"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"8"	"0"	"25.4"	"19.9"	"26.8"	"23.8"	"24.7"	"29.9"	"41.4"	"0.0"	"802.2"	"860.2"	"1661.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P35558"	"Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Homo sapiens OX=9606 GN=PCK1 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"622"	"69.2"	"6.14"	""	"2.68"	""	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00821, Pf17297"	"5105"	"ENSG00000124253"	"PCK1"	"A8K437; B4DT64; hsa:5105; P35558; Q8TCA3; Q9UJD2"	"Gluconeogenesis; Transcriptional regulation of white adipocyte differentiation; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Abacavir metabolism; NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis"	"Adipogenesis; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Estrogen receptor pathway; Nuclear receptors meta-pathway; Angiopoietin-like protein 8 regulatory pathway; Amino acid metabolism; PPAR signaling pathway; PI3K-Akt signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"15"	"0"	"27.3"	"9.3"	"29.1"	"27.0"	"26.9"	"21.6"	"53.6"	"0.0"	"341.5"	"284.4"	"663.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVD3"	"E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"245"	"28.2"	"6.93"	"341.63"	"2.67"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05605, Pf13923, Pf18574"	"51444"	"ENSG00000134758"	"RNF138"	"B2RE17; hsa:51444; Q8WVD3; Q9H8K2; Q9UF87; Q9UKI6"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"10.2"	"8.6"	"18.3"	"17.4"	"18.8"	"15.5"	"38.9"	"0.0"	"510.2"	"514.7"	"686.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04721"	"Neurogenic locus notch homolog protein 2 OS=Homo sapiens OX=9606 GN=NOTCH2 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2471"	"265.2"	"5.14"	"275.07"	"2.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00008, Pf00066, Pf06816, Pf07645, Pf07684, Pf12661, Pf12796"	"4853"	"ENSG00000134250"	"NOTCH2"	"hsa:4853; Q04721; Q5T3X7; Q99734; Q9H240"	"NOTCH2 Activation and Transmission of Signal to the Nucleus; Pre-NOTCH Processing in Golgi; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; Pre-NOTCH Processing in the Endoplasmic Reticulum; Defective LFNG causes SCDO3"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; OSX and miRNAs in tooth development; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Head and neck squamous cell carcinoma; Osteoblast differentiation and related diseases; Genes controlling nephrogenesis; Primary ovarian insufficiency; Notch signaling pathway"	"19"	"0"	"7.4"	"5.4"	"8.8"	"7.5"	"7.6"	"8.8"	"9.9"	"0.0"	"94.7"	"93.2"	"208.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q4KWH8"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 OS=Homo sapiens OX=9606 GN=PLCH1 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1693"	"189.1"	"7.74"	""	"2.67"	""	"1"	"other metabolic processes;transport;signal transduction"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf09279"	"23007"	"ENSG00000114805"	"PLCH1"	"hsa:23007; Q29RV9; Q4KWH8; Q4KWH9; Q68CN0; Q86XK4; Q9H9U2; Q9UPT3"	"Synthesis of IP3 and IP4 in the cytosol"	"Mesodermal commitment pathway; GPR40 pathway"	"3"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"3.2"	"0.0"	"0.0"	"1.8"	"42.4"	"32.2"	"55.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92759"	"General transcription factor IIH subunit 4 OS=Homo sapiens OX=9606 GN=GTF2H4 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"462"	"52.2"	"9.04"	"302.25"	"2.67"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03849, Pf18307"	"2968"	"ENSG00000213780; ENSG00000221974; ENSG00000226384; ENSG00000233149; ENSG00000234370; ENSG00000236895"	"GTF2H4"	"B4DTJ5; hsa:2968; Q76KU4; Q92759"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"33"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.9"	"0.0"	"22.2"	"22.8"	"72.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95208"	"Epsin-2 OS=Homo sapiens OX=9606 GN=EPN2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"641"	"68.4"	"7.52"	"278.78"	"2.66"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"22905"	"ENSG00000072134"	"EPN2"	"A8MTV8; B3KRX8; E9PBC2; hsa:22905; O95207; O95208; Q52LD0; Q9H7Z2; Q9UPT7"	"Cargo recognition for clathrin-mediated endocytosis"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H814"	"Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"394"	"44.4"	"5.40"	"266.22"	"2.66"	"1"	"1"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10258"	"51808"	"ENSG00000164902"	"PHAX"	"hsa:51808; Q9H814; Q9H8W1"	"RNA polymerase II transcribes snRNA genes; snRNP Assembly"	""	"2"	"0"	"13.2"	"11.8"	"14.0"	"12.2"	"13.6"	"11.6"	"18.7"	"1.2"	"34.6"	"29.3"	"65.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96008"	"Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"361"	"37.9"	"7.25"	"289.42"	"2.66"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"transporter activity"	"Pf01459"	"10452"	"ENSG00000130204"	"TOMM40"	"A0A024R0P9; hsa:10452; O96008; Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95"	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"IL-18 signaling pathway"	"3"	"0"	"0.0"	"0.0"	"3.1"	"0.0"	"2.2"	"2.4"	"2.8"	"1.5"	"32.1"	"30.1"	"66.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76031"	"ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial OS=Homo sapiens OX=9606 GN=CLPX PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"633"	"69.2"	"7.58"	"307.84"	"2.66"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07724, Pf10431"	"10845"	"ENSG00000166855"	"CLPX"	"A1L428; A8K8F1; B9EGI8; hsa:10845; O76031; Q9H4D9"	""	""	"0"	"0"	"2.8"	"4.3"	"2.3"	"2.2"	"3.3"	"3.5"	"3.8"	"0.0"	"33.4"	"39.7"	"70.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NYV6"	"RNA polymerase I-specific transcription initiation factor RRN3 OS=Homo sapiens OX=9606 GN=RRN3 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"651"	"74.1"	"5.63"	""	"2.65"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05327"	"54700"	"ENSG00000085721; ENSG00000278494"	"RRN3"	"A2RTY9; B4E0J7; B4E3T2; hsa:54700; Q3MHU9; Q6IPL4; Q9H4F0; Q9NYV6"	"RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94913"	"Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1555"	"172.9"	"8.48"	"289.00"	"2.65"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04818"	"51585"	"ENSG00000165494"	"PCF11"	"A6H8W7; hsa:51585; O43671; O94913; Q6P0X8"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RNA polymerase II transcribes snRNA genes; Processing of Intronless Pre-mRNAs"	""	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUW1"	"Protein BRICK1 OS=Homo sapiens OX=9606 GN=BRK1 PE=1 SV=1"	"0.000"	""	"33"	"2"	"3"	"2"	"75"	"8.7"	"5.45"	"767.36"	"2.65"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"55845"	"ENSG00000254999"	"BRK1"	"B2R5E2; hsa:55845; Q8WUW1; Q9P082"	"RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway; RAC2 GTPase cycle; RAC3 GTPase cycle"	"Regulation of actin cytoskeleton"	"8"	"0"	"5.7"	"0.0"	"3.1"	"4.2"	"10.1"	"8.4"	"20.3"	"1.5"	"321.5"	"307.2"	"746.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYU2"	"UDP-glucose:glycoprotein glucosyltransferase 1 OS=Homo sapiens OX=9606 GN=UGGT1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1555"	"177.1"	"5.63"	"398.89"	"2.65"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"ER/Golgi;other cell component"	"other molecular function"	"Pf06427, Pf18400, Pf18401, Pf18402, Pf18403, Pf18404"	"56886"	"ENSG00000136731"	"UGGT1"	"hsa:56886; Q53QP2; Q53SL3; Q8IW30; Q9H8I4; Q9NYU2"	"ER Quality Control Compartment (ERQC)"	"IL-18 signaling pathway"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99963"	"Endophilin-A3 OS=Homo sapiens OX=9606 GN=SH3GL3 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"347"	"39.3"	"5.38"	""	"2.64"	""	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6457"	"ENSG00000140600"	"SH3GL3"	"hsa:6457; O43553; O43554; Q99963"	"NGF-stimulated transcription; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"EGF/EGFR signaling pathway; Fragile X syndrome; 10q22q23 copy number variation; 15q25 copy number variation"	"10"	"0"	"213.2"	"167.9"	"193.6"	"185.6"	"208.5"	"240.8"	"370.0"	"0.0"	"889.3"	"820.8"	"1443.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00264"	"Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"195"	"21.7"	"4.70"	"235.87"	"2.64"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00173"	"10857"	"ENSG00000101856"	"PGRMC1"	"B7Z1L3; hsa:10857; O00264; Q9UGJ9"	"Neutrophil degranulation"	"Primary ovarian insufficiency"	"2"	"0"	"24.5"	"21.0"	"36.3"	"26.3"	"24.0"	"24.8"	"37.2"	"0.3"	"172.1"	"160.2"	"344.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95835"	"Serine/threonine-protein kinase LATS1 OS=Homo sapiens OX=9606 GN=LATS1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1130"	"126.8"	"8.70"	"299.00"	"2.64"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00627"	"9113"	"ENSG00000131023"	"LATS1"	"hsa:9113; O95835; Q6PKD0"	"Signaling by Hippo"	"Mesodermal commitment pathway; Transcription co-factors SKI and SKIL protein partners; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Leukocyte-intrinsic Hippo pathway functions; Pleural mesothelioma"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NKF1"	"SAC3 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAC3D1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"404"	"43.5"	"8.69"	"361.06"	"2.64"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf03399"	""	""	"SAC3D1"	"A6NKF1; A8MX08; Q99773"	""	""	"0"	"0"	"7.8"	"6.3"	"9.9"	"10.3"	"2.8"	"5.2"	"22.0"	"0.0"	"143.4"	"169.9"	"280.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00203"	"AP-3 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP3B1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1094"	"121.2"	"6.04"	""	"2.64"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf14796, Pf14797"	"8546"	"ENSG00000132842"	"AP3B1"	"E5RJ68; hsa:8546; O00203; O00580; Q7Z393; Q9HD66"	"Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95696"	"Bromodomain-containing protein 1 OS=Homo sapiens OX=9606 GN=BRD1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1058"	"119.4"	"8.60"	"286.50"	"2.64"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf10513, Pf13831, Pf13832"	"23774"	"ENSG00000100425"	"BRD1"	"A6ZJA4; hsa:23774; O95696"	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	"Pathways affected in adenoid cystic carcinoma"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14316"	"Interferon regulatory factor 2 OS=Homo sapiens OX=9606 GN=IRF2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"349"	"39.3"	"7.52"	"281.91"	"2.64"	"1"	"1"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00605"	"3660"	"ENSG00000168310"	"IRF2"	"D6RCK5; H0Y8S3; hsa:3660; P14316; Q6IAS7; Q96B99"	"Interferon gamma signaling; Factors involved in megakaryocyte development and platelet production; Interferon alpha/beta signaling; Pyroptosis"	"Apoptosis; Type II interferon signaling"	"6"	"0"	"0.0"	"2.6"	"3.5"	"4.8"	"4.6"	"3.6"	"7.8"	"0.0"	"32.7"	"27.1"	"54.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q01658"	"Protein Dr1 OS=Homo sapiens OX=9606 GN=DR1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"176"	"19.4"	"4.75"	""	"2.64"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"1810"	"ENSG00000117505"	"DR1"	"hsa:1810; Q01658"	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	""	"2"	"0"	"44.4"	"39.5"	"58.3"	"53.0"	"49.0"	"54.3"	"110.8"	"0.0"	"646.3"	"897.4"	"1720.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75529"	"TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L OS=Homo sapiens OX=9606 GN=TAF5L PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"589"	"66.1"	"5.88"	"255.75"	"2.64"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04494"	"27097"	"ENSG00000135801"	"TAF5L"	"hsa:27097; O75529; Q5TDI5; Q5TDI6; Q8IW31"	"HATs acetylate histones"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCE1"	"Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1003"	"113.6"	"8.82"	"334.39"	"2.64"	"1"	"1"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13087, Pf13604"	"4343"	"ENSG00000155363"	"MOV10"	"hsa:4343; Q5JR03; Q8TEF0; Q9BSY3; Q9BUJ9; Q9HCE1"	"TP53 Regulates Metabolic Genes; MAPK6/MAPK4 signaling; Oxidative Stress Induced Senescence; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Ca2+ pathway; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"VEGFA-VEGFR2 signaling"	"18"	"0"	"4.5"	"3.4"	"10.5"	"10.4"	"6.7"	"6.1"	"20.1"	"0.7"	"140.0"	"150.7"	"353.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16219"	"Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADS PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"412"	"44.3"	"7.99"	"254.04"	"2.63"	"1"	"1"	"other metabolic processes"	"cytoskeleton;mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"35"	"ENSG00000122971"	"ACADS"	"hsa:35; P16219; P78331"	"Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DP5"	"Methionyl-tRNA formyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=MTFMT PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"389"	"43.8"	"9.66"	"301.59"	"2.62"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00551, Pf02911"	"123263"	"ENSG00000103707"	"MTFMT"	"B7Z734; hsa:123263; Q96DP5"	"Mitochondrial translation initiation"	"One-carbon metabolism"	"2"	"0"	"2.3"	"0.0"	"7.3"	"6.0"	"4.7"	"4.5"	"7.6"	"1.9"	"55.2"	"53.1"	"126.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13200"	"26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"908"	"100.1"	"5.20"	"371.71"	"2.62"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01851, Pf17781, Pf18051"	"5708"	"ENSG00000175166"	"PSMD2"	"B4DX07; B4DXY1; E7EW34; E9PCS3; hsa:5708; Q12932; Q13200; Q15321; Q53XQ4; Q96I12"	"Separation of Sister Chromatids; Neddylation; Neutrophil degranulation; Antigen processing: Ubiquitination & Proteasome degradation; UCH proteinases; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Regulation of expression of SLITs and ROBOs; Degradation of beta-catenin by the destruction complex; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"65"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12277"	"Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"381"	"42.6"	"5.59"	"302.16"	"2.62"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1152"	"ENSG00000166165"	"CKB"	"A8K236; B2R5R4; hsa:1152; P12277; Q2LE07; Q6FG40; Q9UC66"	"RND3 GTPase cycle; Creatine metabolism"	""	"2"	"0"	"6.0"	"2.2"	"6.8"	"5.4"	"7.3"	"5.1"	"10.7"	"1.0"	"74.1"	"71.0"	"146.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95363"	"Phenylalanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=FARS2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"451"	"52.3"	"7.46"	"301.02"	"2.61"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf03147"	"10667"	"ENSG00000145982"	"FARS2"	"B2R664; hsa:10667; O95363; Q53F66; Q5TCS3; Q6FG29; Q9NPY7; Q9P062"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"3.9"	"0.0"	"3.4"	"0.0"	"3.5"	"3.7"	"5.5"	"0.0"	"41.2"	"37.0"	"66.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15369"	"Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"112"	"12.5"	"4.78"	"360.23"	"2.61"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03931"	"6921"	"ENSG00000154582"	"ELOC"	"E5RGD9; hsa:6921; Q15369; Q567Q6"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling"	"Dual hijack model of Vif in HIV infection; VEGFA-VEGFR2 signaling; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"21"	"0"	"5.4"	"7.4"	"13.8"	"9.8"	"11.2"	"10.2"	"17.4"	"0.0"	"335.0"	"353.5"	"690.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49327"	"Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2511"	"273.3"	"6.44"	"296.36"	"2.61"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf14765, Pf16197"	"2194"	"ENSG00000169710"	"FASN"	"hsa:2194; P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0"	"ChREBP activates metabolic gene expression; Activation of gene expression by SREBF (SREBP); Fatty acyl-CoA biosynthesis; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Vitamin B5 (pantothenate) metabolism"	"AMP-activated protein kinase signaling; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X receptor pathway; Nuclear receptors meta-pathway; Fatty acid biosynthesis; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-9 fatty acid synthesis; FOXA2 pathway"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15047"	"Histone-lysine N-methyltransferase SETD1A OS=Homo sapiens OX=9606 GN=SETD1A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1707"	"185.9"	"5.14"	"273.42"	"2.61"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00856, Pf11764"	"9739"	"ENSG00000099381"	"SETD1A"	"A6NP62; hsa:9739; O15047; Q6PIF3; Q8TAJ6"	"Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"Histone modifications"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14692"	"Ribosome biogenesis protein BMS1 homolog OS=Homo sapiens OX=9606 GN=BMS1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1282"	"145.7"	"6.44"	"280.00"	"2.60"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"9790"	"ENSG00000165733"	"BMS1"	"hsa:9790; Q14692; Q5QPT5; Q86XJ9"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"0.0"	"0.0"	"0.0"	"2.8"	"0.0"	"0.0"	"8.7"	"0.0"	"35.9"	"29.8"	"56.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P587"	"Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"224"	"24.8"	"7.39"	"320.50"	"2.60"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01557"	"81889"	"ENSG00000180185"	"FAHD1"	"B1AK40; B1AK41; hsa:81889; Q6FIC7; Q6P587; Q96RY1; Q9H0N6"	"Citric acid cycle (TCA cycle)"	""	"1"	"0"	"10.6"	"7.7"	"10.6"	"12.4"	"14.3"	"12.5"	"19.8"	"0.0"	"320.5"	"355.8"	"675.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71RC2"	"La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"724"	"80.5"	"6.61"	"893.49"	"2.60"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf05383"	"113251"	"ENSG00000161813"	"LARP4"	"A8K6T1; E9PDG5; G3XAA8; G5E976; hsa:113251; Q5CZ97; Q6ZV14; Q71RC2; Q96NF9"	""	""	"0"	"0"	"18.8"	"15.2"	"21.3"	"19.1"	"25.7"	"23.3"	"54.9"	"1.7"	"206.7"	"183.9"	"305.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75569"	"Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"313"	"34.4"	"8.41"	"241.58"	"2.60"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00035"	"8575"	"ENSG00000180228"	"PRKRA"	"A8K3I6; hsa:8575; O75569; Q53G24; Q6X7T5; Q8NDK4"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host"	"4"	"0"	"4.2"	"3.1"	"3.0"	"3.9"	"5.9"	"3.6"	"7.2"	"0.0"	"25.7"	"30.2"	"40.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJX2"	"Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"597"	"68.8"	"7.02"	"317.64"	"2.60"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf04049"	"8697"	"ENSG00000094880"	"CDC23"	"A8K6E5; B4E3A2; B7WP05; D3DQB7; hsa:8697; O75433; Q53FN2; Q9BS73; Q9UJX2"	"Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC-Cdc20 mediated degradation of Nek2A; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"Cell cycle"	"19"	"0"	"17.3"	"11.5"	"18.7"	"14.5"	"16.9"	"13.0"	"34.9"	"0.0"	"334.4"	"321.5"	"933.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00469"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens OX=9606 GN=PLOD2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"737"	"84.6"	"6.71"	""	"2.60"	""	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"5352"	"ENSG00000152952"	"PLOD2"	"B3KWS3; hsa:5352; O00469; Q59ED2; Q8N170"	"Collagen biosynthesis and modifying enzymes"	"Clear cell renal cell carcinoma pathways; Type I collagen synthesis in the context of osteogenesis imperfecta"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BX63"	"Fanconi anemia group J protein OS=Homo sapiens OX=9606 GN=BRIP1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1249"	"140.8"	"6.92"	""	"2.60"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06733, Pf13307"	"83990"	"ENSG00000136492"	"BRIP1"	"A0A024QZ45; hsa:83990; Q3MJE2; Q8NCI5; Q9BX63"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Resolution of D-loop Structures through Holliday Junction Intermediates; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Cytosolic iron-sulfur cluster assembly"	"DNA repair pathways, full network"	"16"	"0"	"72.9"	"74.4"	"81.0"	"82.2"	"75.6"	"82.2"	"106.2"	"0.0"	"532.4"	"506.7"	"831.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4C2"	"TRPM8 channel-associated factor 1 OS=Homo sapiens OX=9606 GN=TCAF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"921"	"102.1"	"6.54"	"336.18"	"2.59"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf13402, Pf17291"	"9747"	"ENSG00000198420"	"TCAF1"	"A8K6E0; hsa:9747; Q75KM8; Q75KM9; Q7L665; Q9BW63; Q9Y4C2"	""	""	"0"	"0"	"13.6"	"8.3"	"23.6"	"15.1"	"20.8"	"15.8"	"31.8"	"0.5"	"227.1"	"208.8"	"462.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P48553"	"Trafficking protein particle complex subunit 10 OS=Homo sapiens OX=9606 GN=TRAPPC10 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1259"	"142.1"	"6.04"	""	"2.59"	""	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf12584"	"7109"	"ENSG00000160218"	"TRAPPC10"	"hsa:7109; P48553; Q3MIR2; Q86SI7; Q9UMD4; Q9Y4L3"	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXI6"	"TBC1 domain family member 10A OS=Homo sapiens OX=9606 GN=TBC1D10A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"508"	"57.1"	"8.44"	"234.12"	"2.59"	"1"	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"83874"	"ENSG00000099992"	"TBC1D10A"	"B3KXT8; hsa:83874; O76053; Q20WK7; Q543A2; Q9BXI6"	"TBC/RABGAPs"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"2"	"0"	"3.0"	"0.0"	"7.4"	"4.3"	"4.2"	"6.8"	"11.4"	"2.0"	"167.6"	"156.0"	"294.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y462"	"Zinc finger protein 711 OS=Homo sapiens OX=9606 GN=ZNF711 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"761"	"86.2"	"6.87"	"351.67"	"2.59"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf04704, Pf13909"	"7552"	"ENSG00000147180"	"ZNF711"	"B4DSV4; hsa:7552; Q6NX42; Q9Y462; Q9Y4J6"	"Generic Transcription Pathway"	""	"1"	"0"	"5.0"	"3.6"	"4.6"	"4.5"	"2.4"	"4.3"	"6.9"	"0.0"	"27.5"	"25.7"	"54.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ41"	"Rab5 GDP/GTP exchange factor OS=Homo sapiens OX=9606 GN=RABGEF1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"491"	"56.9"	"7.02"	"274.03"	"2.59"	"1"	"1"	"protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01754, Pf02204, Pf18151"	"27342"	"ENSG00000154710"	"RABGEF1"	"B4DZM7; hsa:27342; Q3HKR2; Q3HKR3; Q53FG0; Q9UJ41"	"RAB GEFs exchange GTP for GDP on RABs; TBC/RABGAPs"	"16p11.2 distal deletion syndrome"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43237"	"Cytoplasmic dynein 1 light intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1LI2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"492"	"54.1"	"6.38"	"311.85"	"2.58"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05783"	"1783"	"ENSG00000135720"	"DYNC1LI2"	"A8K6V1; B4DZP4; hsa:1783; O43237; Q8TAT3"	"HCMV Early Events; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Intraflagellar transport proteins binding to dynein"	"13"	"0"	"4.3"	"0.0"	"3.0"	"5.4"	"2.5"	"3.3"	"5.7"	"0.0"	"36.2"	"33.6"	"72.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54277"	"PMS1 protein homolog 1 OS=Homo sapiens OX=9606 GN=PMS1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"932"	"105.8"	"6.67"	"298.19"	"2.58"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf01119, Pf02518"	"5378"	"ENSG00000064933"	"PMS1"	"D3DPI1; hsa:5378; P54277; Q4VAL4; Q5FBZ3; Q5FBZ6; Q5FBZ8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92552"	"28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"414"	"47.6"	"6.18"	"741.94"	"2.58"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10037"	"23107"	"ENSG00000113048"	"MRPS27"	"B4DRT2; hsa:23107; Q6P1S1; Q92552"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"34.4"	"27.6"	"33.8"	"33.6"	"34.0"	"31.2"	"89.2"	"5.2"	"554.8"	"551.8"	"1037.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPN4"	"Centrosomal protein of 131 kDa OS=Homo sapiens OX=9606 GN=CEP131 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1083"	"122.1"	"8.69"	""	"2.57"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"22994"	"ENSG00000141577"	"CEP131"	"A6NHI8; B2RN11; hsa:22994; Q96F50; Q9UPN4"	"Recruitment of mitotic centrosome proteins and complexes; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"6.9"	"5.2"	"15.1"	"7.2"	"10.3"	"5.7"	"14.5"	"4.0"	"62.9"	"68.4"	"134.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q16222"	"UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens OX=9606 GN=UAP1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"522"	"58.7"	"6.33"	""	"2.57"	""	"1"	"other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf01704"	"6675"	"ENSG00000117143"	"UAP1"	"B2R6R8; hsa:6675; Q16222; Q5VTA9; Q5VTB0; Q5VTB1; Q96GM2"	"Synthesis of UDP-N-acetyl-glucosamine"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"19.4"	"22.1"	"187.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KQ4"	"Apoptosis-stimulating of p53 protein 1 OS=Homo sapiens OX=9606 GN=PPP1R13B PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1090"	"119.5"	"6.76"	"285.77"	"2.57"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00023"	"23368"	"ENSG00000088808"	"PPP1R13B"	"B2RMX5; hsa:23368; O94870; Q96KQ4"	"TP53 Regulates Transcription of Death Receptors and Ligands; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors"	""	"5"	"0"	"11.9"	"7.2"	"8.2"	"11.3"	"7.6"	"12.0"	"23.1"	"2.3"	"65.5"	"59.3"	"106.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"B2RTY4"	"Unconventional myosin-IXa OS=Homo sapiens OX=9606 GN=MYO9A PE=1 SV=2"	"0.000"	""	"0"	"1"	"2"	"1"	"2548"	"292.5"	"8.88"	"291.95"	"2.57"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf00620, Pf00788"	"4649"	"ENSG00000066933"	"MYO9A"	"B0I1T5; B2RTY4; C9IYB3; C9JA86; hsa:4649; Q14787; Q3YLD7; Q3YLD8; Q6P986; Q9H8T5; Q9NTG2; Q9NUY2; Q9UEP3; Q9UNJ2"	"RHOA GTPase cycle; RHOB GTPase cycle; RHOV GTPase cycle"	""	"3"	"0"	"6.0"	"6.9"	"4.9"	"6.0"	"3.2"	"3.1"	"11.1"	"2.8"	"73.3"	"50.0"	"142.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBC2"	"Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"864"	"94.2"	"5.11"	"363.76"	"2.56"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"58513"	"ENSG00000127527"	"EPS15L1"	"A2RRF3; A5PL29; B4DKA3; hsa:58513; Q9UBC2"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"EGF/EGFR signaling pathway"	"4"	"0"	"46.4"	"27.8"	"30.1"	"44.3"	"36.9"	"30.1"	"16.5"	"0.4"	"91.6"	"88.7"	"175.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q53H96"	"Pyrroline-5-carboxylate reductase 3 OS=Homo sapiens OX=9606 GN=PYCR3 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"274"	"28.6"	"7.72"	""	"2.55"	""	"1"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03807, Pf14748"	"65263"	"ENSG00000104524; ENSG00000276657"	"PYCR3"	"B3KMB5; B4DVT6; H0Y6C3; hsa:65263; Q53H96; Q8N3N9; Q96HX4; Q9H896"	"Glutamate and glutamine metabolism"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.7"	"0.0"	"4.2"	"0.0"	"38.9"	"38.3"	"91.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14828"	"Secretory carrier-associated membrane protein 3 OS=Homo sapiens OX=9606 GN=SCAMP3 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"347"	"38.3"	"7.64"	"233.43"	"2.55"	"1"	"1"	"transport"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04144"	"10067"	"ENSG00000116521; ENSG00000263290"	"SCAMP3"	"A9Z1W6; B1AVS6; hsa:10067; O14828; O15128; Q96FR8; Q9BPY0"	""	""	"0"	"0"	"3.0"	"2.2"	"6.0"	"0.0"	"5.4"	"5.8"	"7.7"	"1.6"	"38.7"	"36.8"	"65.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXM3"	"39S ribosomal protein L41, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL41 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"137"	"15.4"	"9.57"	"314.09"	"2.55"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;other cell component"	"other molecular function"	"Pf09809"	"64975"	"ENSG00000182154"	"MRPL41"	"hsa:64975; Q8IXM3; Q96Q49"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"34.7"	"17.0"	"53.3"	"34.5"	"38.7"	"38.5"	"74.7"	"0.0"	"411.9"	"463.6"	"910.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXI1"	"Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"618"	"68.1"	"5.86"	"285.25"	"2.55"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"89941"	"ENSG00000140983"	"RHOT2"	"A2IDC2; hsa:89941; Q8IXI1; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8"	"RHOT2 GTPase cycle"	""	"1"	"0"	"2.8"	"0.0"	"3.8"	"0.0"	"3.4"	"0.0"	"3.0"	"0.0"	"23.2"	"24.7"	"64.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16637"	"Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"294"	"31.8"	"6.55"	"532.22"	"2.55"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06003"	"6606; 6607"	"ENSG00000172062; ENSG00000205571; ENSG00000273772; ENSG00000275349; ENSG00000277773"	"SMN1; SMN2"	"A8K0V4; hsa:6606; hsa:6607; Q13119; Q16637; Q549U5; Q96J51"	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	""	"2"	"0"	"220.4"	"165.7"	"178.4"	"185.5"	"148.2"	"146.8"	"347.4"	"0.0"	"1051.4"	"1188.5"	"2250.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5A7"	"NEDD8 ultimate buster 1 OS=Homo sapiens OX=9606 GN=NUB1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"615"	"70.5"	"5.96"	"308.91"	"2.54"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	""	"Pf00627, Pf18037"	"51667"	"ENSG00000013374"	"NUB1"	"hsa:51667; O95422; Q75MR9; Q8IX22; Q9BXR2; Q9Y5A7"	""	""	"0"	"0"	"47.7"	"39.3"	"61.5"	"47.1"	"52.7"	"52.5"	"82.1"	"0.0"	"650.8"	"695.8"	"1529.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5T1M5"	"FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1219"	"133.5"	"5.20"	""	"2.54"	""	"1"	"transport"	"other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254"	"23307"	"ENSG00000119321"	"FKBP15"	"hsa:23307; Q05DK8; Q5T1M2; Q5T1M5; Q6DD85; Q9Y4D0"	""	"TYROBP causal network in microglia"	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.2"	"0.0"	"25.2"	"22.3"	"67.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPQ9"	"Trinucleotide repeat-containing gene 6B protein OS=Homo sapiens OX=9606 GN=TNRC6B PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1833"	"193.9"	"6.76"	""	"2.53"	""	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10427, Pf16608"	"23112"	"ENSG00000100354"	"TNRC6B"	"B0QY73; B0QY78; B4DGC0; hsa:23112; Q5TH52; Q8TBX2; Q9UPQ9"	"Oxidative Stress Induced Senescence; Estrogen-dependent gene expression; MAPK6/MAPK4 signaling; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Ca2+ pathway; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	""	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18206"	"Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1134"	"123.7"	"5.66"	"275.10"	"2.53"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"7414"	"ENSG00000035403"	"VCL"	"hsa:7414; P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7"	"Neutrophil degranulation; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; VEGFA-VEGFR2 signaling; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Melanoma; Regulation of actin cytoskeleton"	"18"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.0"	"2.7"	"0.0"	"29.7"	"29.1"	"65.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NE86"	"Calcium uniporter protein, mitochondrial OS=Homo sapiens OX=9606 GN=MCU PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"351"	"39.8"	"8.65"	"319.17"	"2.53"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04678"	"90550"	"ENSG00000156026"	"MCU"	"B2RDF3; B3KXV7; hsa:90550; Q8NE86; Q96FL3"	"Processing of SMDT1"	"Alzheimer's disease and miRNA effects; Pleural mesothelioma; Alzheimer's disease"	"5"	"0"	"9.9"	"8.9"	"12.3"	"9.8"	"10.6"	"8.9"	"21.7"	"0.3"	"73.0"	"64.2"	"105.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49841"	"Glycogen synthase kinase-3 beta OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"420"	"46.7"	"8.78"	"256.88"	"2.52"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"2932"	"ENSG00000082701"	"GSK3B"	"D3DN89; hsa:2932; P49841; Q9BWH3; Q9UL47"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Ubiquitin-dependent degradation of Cyclin D; Regulation of RUNX2 expression and activity; Regulation of HSF1-mediated heat shock response; Constitutive Signaling by AKT1 E17K in Cancer; B-WICH complex positively regulates rRNA expression; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; CRMPs in Sema3A signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; AKT phosphorylates targets in the cytosol; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein; Maturation of nucleoprotein"	"IL-5 signaling pathway; Androgen receptor signaling pathway; Energy metabolism; MicroRNAs in cardiomyocyte hypertrophy; Cell cycle; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; IL-17 signaling pathway; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac progenitor differentiation; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Focal adhesion; Copper homeostasis; Melatonin metabolism and effects; Wnt signaling pathway; IL6 signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Regulation of apoptosis by parathyroid hormone-related protein; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K/AKT/mTOR - vitamin D3 signaling; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; Acute viral myocarditis; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; NRF2-ARE regulation; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Gastrin signaling pathway; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Influence of laminopathies on Wnt signaling; MAP3K1 role in promoting and blocking gonadal determination; Overlap between signal transduction pathways contributing to LMNA laminopathies; Glycogen synthesis and degradation; Pleural mesothelioma; CCL18 signaling pathway; Alzheimer's disease; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; Neurogenesis regulation in the olfactory epithelium; Sildenafil treatment; A network map of Macrophage-stimulating protein (MSP) signaling; Notch signaling pathway; ErbB signaling pathway; DNA damage response (only ATM dependent)"	"93"	"0"	"19.7"	"17.7"	"19.3"	"17.8"	"18.1"	"24.2"	"64.4"	"0.0"	"450.4"	"474.0"	"939.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28482"	"Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"360"	"41.4"	"6.98"	"282.93"	"2.52"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"5594"	"ENSG00000100030"	"MAPK1"	"A8CZ64; hsa:5594; P28482"	"Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; Recycling pathway of L1; FCERI mediated MAPK activation; FCGR3A-mediated phagocytosis; NPAS4 regulates expression of target genes; RHO GTPases Activate WASPs and WAVEs; Regulation of HSF1-mediated heat shock response; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Signaling by NODAL; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interferon gamma signaling; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Growth hormone receptor signaling; Regulation of the apoptosome activity; Signal transduction by L1; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; Downregulation of SMAD2/3:SMAD4 transcriptional activity; RUNX2 regulates osteoblast differentiation; RSK activation; Estrogen-stimulated signaling through PRKCZ; Spry regulation of FGF signaling; Suppression of apoptosis; MAPK1 (ERK2) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; IFNG signaling activates MAPKs; Golgi Cisternae Pericentriolar Stack Reorganization; Signaling by Activin; Activation of the AP-1 family of transcription factors; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Signal attenuation; Gastrin-CREB signalling pathway via PKC and MAPK; Nuclear events stimulated by ALK signaling in cancer; ESR-mediated signaling; Negative feedback regulation of MAPK pathway; Advanced glycosylation endproduct receptor signaling; RHO GTPases Activate NADPH Oxidases; ERKs are inactivated; Signaling by MAP2K mutants; phospho-PLA2 pathway; Signaling by MAPK mutants"	"IL-5 signaling pathway; Osteopontin signaling; Physiological and pathological hypertrophy of the heart; Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; Heart development; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; PDGF pathway; Aryl hydrocarbon receptor pathway; S1P receptor signal transduction; Ebstein-Barr virus LMP1 signaling; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; TCA cycle nutrient use and invasiveness of ovarian cancer; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; ERK pathway in Huntington's disease; Toll-like receptor signaling related to MyD88; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Prion disease pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Bile acids synthesis and enterohepatic circulation ; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Regulatory circuits of the STAT3 signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Regucalcin in proximal tubule epithelial kidney cells; Kisspeptin/kisspeptin receptor system in the ovary; MAP3K1 role in promoting and blocking gonadal determination; CAMKK2 pathway; Disruption of postsynaptic signaling by CNV; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; RAS and bradykinin pathways in COVID-19; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Sphingolipid metabolism in senescence; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; 2q11.2 copy number variation syndrome; 2q13 copy number variation syndrome; Hippocampal synaptogenesis and neurogenesis; Comprehensive IL-17A signaling; Genetic causes of porto-sinusoidal vascular disease; Female steroid hormones in cardiomyocyte energy metabolism; Cardiomyocyte signaling pathways converging on Titin; 8p23.1 copy number variation syndrome; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; NPHP1 deletion syndrome; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Estrogen signaling pathway; Vitamin A and carotenoid metabolism; Toll-like receptor signaling pathway"	"200"	"0"	"51.4"	"36.8"	"52.5"	"45.4"	"43.4"	"52.7"	"94.4"	"0.0"	"624.9"	"672.7"	"1336.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95071"	"E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2"	"0.000"	""	"1"	"3"	"3"	"3"	"2799"	"309.2"	"5.85"	"495.44"	"2.52"	"2"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00632, Pf00658, Pf11547"	"51366"	"ENSG00000104517"	"UBR5"	"B2RP24; hsa:51366; J3KMW7; O94970; O95071; Q9NPL3"	""	"Mesodermal commitment pathway"	"1"	"0"	"83.1"	"55.4"	"72.8"	"60.4"	"60.7"	"64.9"	"141.2"	"0.5"	"920.9"	"974.5"	"1905.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TEU4"	"Arginine-hydroxylase NDUFAF5, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAF5 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"345"	"38.9"	"6.57"	"278.03"	"2.52"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf08241"	"79133"	"ENSG00000101247"	"NDUFAF5"	"A8K166; hsa:79133; Q5TEU4; Q6GPH3; Q9H6F4"	"Complex I biogenesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DPB5"	"Protein POLR1D, isoform 2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1"	"0.000"	""	"12"	"2"	"2"	"2"	"122"	"14.3"	"9.88"	"282.27"	"2.52"	"1"	"1"	""	"cytosol;nucleus"	""	""	"51082"	"ENSG00000186184"	"POLR1D"	"P0DPB5; Q5TBX2; Q96BR3; Q9Y2S0"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"16"	"0"	"141.9"	"106.6"	"145.0"	"139.5"	"103.6"	"126.5"	"454.0"	"0.0"	"1586.0"	"1543.1"	"3257.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2K5"	"Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"600"	"64.1"	"8.75"	"290.67"	"2.52"	"1"	"1"	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"50804"	"ENSG00000104177"	"MYEF2"	"A7MCZ9; C9J921; C9K0J4; hsa:50804; Q6NUM5; Q7L388; Q7Z4B7; Q9H922; Q9NUQ1; Q9P2K5"	""	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Mitochondrial gene expression"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14739"	"Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"615"	"70.7"	"9.36"	"494.21"	"2.51"	"2"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01222, Pf09465"	"3930"	"ENSG00000143815"	"LBR"	"B2R5P3; hsa:3930; Q14739; Q14740; Q53GU7; Q59FE6"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOD GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of MECP2 expression and activity; Initiation of Nuclear Envelope (NE) Reformation; Cholesterol biosynthesis"	"Gastric cancer network 2; ATM signaling in development and disease ; Envelope proteins and their potential roles in EDMD physiopathology; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"19"	"0"	"153.3"	"93.1"	"163.9"	"169.0"	"143.4"	"139.4"	"252.3"	"1.1"	"1202.5"	"1135.2"	"2276.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TF09"	"Dynein light chain roadblock-type 2 OS=Homo sapiens OX=9606 GN=DYNLRB2 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"96"	"10.8"	"7.50"	"433.46"	"2.51"	"1"	"1"	"other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03259"	"83657"	"ENSG00000168589"	"DYNLRB2"	"hsa:83657; Q8TF09"	"Intraflagellar transport"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"4"	"0"	"36.6"	"28.2"	"43.3"	"43.5"	"33.6"	"38.4"	"41.4"	"0.0"	"310.3"	"305.2"	"565.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PK04"	"Coiled-coil domain-containing protein 137 OS=Homo sapiens OX=9606 GN=CCDC137 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"289"	"33.2"	"10.93"	"372.30"	"2.51"	"1"	"1"	""	"nucleus;other cell component"	""	""	"339230"	"ENSG00000185298"	"CCDC137"	"hsa:339230; Q6PK04"	""	""	"0"	"0"	"7.9"	"9.4"	"6.9"	"7.5"	"11.1"	"6.5"	"30.7"	"0.0"	"70.9"	"68.6"	"101.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L804"	"Rab11 family-interacting protein 2 OS=Homo sapiens OX=9606 GN=RAB11FIP2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"2"	"2"	"512"	"58.2"	"9.32"	"497.59"	"2.51"	"1"	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"22841"	"ENSG00000107560"	"RAB11FIP2"	"A6NEI4; hsa:22841; Q3I768; Q7L804; Q9Y2F0"	"Vasopressin regulates renal water homeostasis via Aquaporins"	""	"1"	"0"	"0.0"	"3.7"	"0.0"	"2.8"	"2.4"	"6.8"	"47.0"	"0.7"	"114.8"	"137.9"	"98.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20073"	"Annexin A7 OS=Homo sapiens OX=9606 GN=ANXA7 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"488"	"52.7"	"5.68"	"315.21"	"2.51"	"1"	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00191"	"310"	"ENSG00000138279"	"ANXA7"	"hsa:310; P20073; Q5F2H3; Q5T0M6; Q5T0M7"	""	""	"0"	"0"	"24.7"	"20.9"	"39.0"	"37.3"	"33.6"	"13.2"	"39.6"	"0.0"	"176.8"	"174.0"	"320.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULJ8"	"Neurabin-1 OS=Homo sapiens OX=9606 GN=PPP1R9A PE=1 SV=2"	"0.000"	""	"2"	"2"	"2"	"2"	"1098"	"123.3"	"5.10"	"254.64"	"2.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00595, Pf07647, Pf17817"	"55607"	"ENSG00000158528"	"PPP1R9A"	"A1L494; B2RWQ1; E9PCA0; E9PCK6; E9PDX1; F8W7J9; hsa:55607; O76059; Q9NXT2; Q9ULJ8"	""	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	"1"	"0"	"41.6"	"34.7"	"49.6"	"41.4"	"40.1"	"33.9"	"55.1"	"0.2"	"356.7"	"393.4"	"727.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43674"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB5 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"189"	"21.7"	"9.63"	""	"2.50"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf09781"	"4711"	"ENSG00000136521"	"NDUFB5"	"hsa:4711; O43674; Q561V6"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"0.0"	"0.0"	"2.4"	"2.1"	"0.0"	"0.0"	"5.1"	"0.0"	"73.4"	"52.0"	"140.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55199"	"RNA polymerase II elongation factor ELL OS=Homo sapiens OX=9606 GN=ELL PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"621"	"68.2"	"9.33"	"791.26"	"2.50"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07303, Pf10390"	"8178"	"ENSG00000105656"	"ELL"	"hsa:8178; P55199"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Transcription-Coupled Nucleotide Excision Repair (TC-NER)"	"Interactome of polycomb repressive complex 2 (PRC2)"	"14"	"0"	"9.5"	"4.9"	"6.9"	"8.3"	"3.5"	"6.6"	"16.8"	"1.0"	"39.5"	"40.9"	"67.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99728"	"BRCA1-associated RING domain protein 1 OS=Homo sapiens OX=9606 GN=BARD1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"777"	"86.6"	"8.72"	"261.37"	"2.50"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00023, Pf14835"	"580"	"ENSG00000138376"	"BARD1"	"F6MDH7; F6MDH8; F6MDH9; hsa:580; O43574; Q53SS5; Q99728"	"UCH proteinases; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Metalloprotease DUBs; Processing of DNA double-strand break ends; Resolution of D-loop Structures through Holliday Junction Intermediates; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Nonhomologous End-Joining (NHEJ); Defective DNA double strand break response due to BRCA1 loss of function; Defective DNA double strand break response due to BARD1 loss of function"	"Retinoblastoma gene in cancer; Pleural mesothelioma; 5q35 copy number variation"	"23"	"0"	"11.5"	"6.4"	"9.6"	"14.8"	"13.9"	"12.0"	"28.3"	"0.0"	"109.1"	"105.4"	"191.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P1Q0"	"Vacuolar protein sorting-associated protein 54 OS=Homo sapiens OX=9606 GN=VPS54 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"977"	"110.5"	"6.55"	""	"2.50"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf07928, Pf10475"	"51542"	"ENSG00000143952"	"VPS54"	"hsa:51542; Q5VIR5; Q86YF7; Q8N6G3; Q9NPV0; Q9NT07; Q9NUJ0; Q9P1Q0"	"Retrograde transport at the Trans-Golgi-Network"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UL03"	"Integrator complex subunit 6 OS=Homo sapiens OX=9606 GN=INTS6 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"887"	"100.3"	"8.62"	"231.02"	"2.50"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf13519, Pf15300"	"26512"	"ENSG00000102786"	"INTS6"	"hsa:26512; Q0P664; Q6PJP4; Q9UFK0; Q9UL03; Q9Y5M9"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	"6.0"	"6.7"	"9.7"	"7.7"	"6.4"	"7.7"	"17.7"	"0.0"	"115.8"	"128.8"	"268.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RS6"	"NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"583"	"66.7"	"5.11"	"306.78"	"2.50"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf04969"	"84955"	"ENSG00000120526"	"NUDCD1"	"B4DVX6; hsa:84955; Q4G130; Q8NDQ5; Q8NG18; Q96RS6; Q96SI4; Q9BVR5"	""	""	"0"	"0"	"23.3"	"16.5"	"25.9"	"16.2"	"21.0"	"23.1"	"36.5"	"0.0"	"513.6"	"522.2"	"988.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3A3"	"MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1"	"0.000"	""	"8"	"2"	"2"	"2"	"225"	"26.0"	"5.78"	"382.49"	"2.49"	"1"	"1"	""	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf03637"	"25843"	"ENSG00000115540"	"MOB4"	"B4DML0; hsa:25843; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y3A3; Q9Y4T8"	""	""	"0"	"0"	"36.3"	"25.6"	"31.5"	"29.9"	"29.6"	"25.2"	"41.5"	"0.0"	"342.7"	"340.2"	"656.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVZ3"	"Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"1"	"263"	"28.3"	"8.38"	"503.24"	"2.49"	"2"	"1"	"transport"	"plasma membrane;other membranes"	""	"Pf07933"	"55707"	"ENSG00000157191"	"NECAP2"	"B4DY19; E9PGQ8; hsa:55707; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1; Q9NVZ3"	"Cargo recognition for clathrin-mediated endocytosis"	""	"2"	"0"	"16.3"	"13.2"	"17.9"	"16.5"	"22.1"	"30.3"	"94.8"	"0.0"	"852.3"	"779.8"	"1349.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07311"	"Acylphosphatase-1 OS=Homo sapiens OX=9606 GN=ACYP1 PE=1 SV=2"	"0.000"	""	"17"	"2"	"3"	"2"	"99"	"11.3"	"9.31"	"534.43"	"2.49"	"2"	"1"	"other metabolic processes"	""	"other molecular function"	"Pf00708"	"97"	"ENSG00000119640"	"ACYP1"	"A6NDV8; B2R590; hsa:97; P07311"	""	""	"0"	"0"	"25.7"	"27.4"	"30.3"	"30.0"	"36.7"	"36.8"	"61.5"	"1.0"	"485.4"	"514.4"	"783.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SU4"	"Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"736"	"83.1"	"6.18"	"773.56"	"2.49"	"2"	"1"	"other metabolic processes;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114883"	"ENSG00000117859"	"OSBPL9"	"B1AKJ8; B3KPQ4; D3DQ31; hsa:114883; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q96SU4; Q9H9X2"	"Synthesis of bile acids and bile salts"	""	"1"	"0"	"9.0"	"6.0"	"13.5"	"6.4"	"11.6"	"7.0"	"20.1"	"0.4"	"174.2"	"187.8"	"458.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25490"	"Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2"	"0.000"	""	"8"	"3"	"5"	"3"	"414"	"44.7"	"6.25"	"1014.18"	"2.49"	"3"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7528"	"ENSG00000100811"	"YY1"	"hsa:7528; P25490; Q14935"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; UCH proteinases; DNA Damage Recognition in GG-NER; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"	"Sterol regulatory element-binding proteins (SREBP) signaling; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Pleural mesothelioma"	"8"	"0"	"90.6"	"49.7"	"90.9"	"93.3"	"80.5"	"71.7"	"163.6"	"2.4"	"746.0"	"783.4"	"1391.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13561"	"Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4"	""	""	"2"	"1"	"1"	"1"	"401"	"44.2"	"5.21"	""	"2.48"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04912"	"10540"	"ENSG00000175203"	"DCTN2"	"B2RBK5; hsa:10540; Q13561; Q86YN2; Q9BW17"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"11"	"0"	"14.6"	"7.0"	"17.3"	"9.4"	"10.9"	"12.5"	"27.3"	"0.0"	"759.1"	"803.4"	"1770.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6J9"	"TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"622"	"67.8"	"8.97"	"320.28"	"2.48"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02969, Pf07571"	"10629"	"ENSG00000162227"	"TAF6L"	"B2RAT0; hsa:10629; Q96HA6; Q9Y6J9"	"HATs acetylate histones"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRK6"	"ATP-binding cassette sub-family B member 10, mitochondrial OS=Homo sapiens OX=9606 GN=ABCB10 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"738"	"79.1"	"9.85"	"324.57"	"2.48"	"1"	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"23456"	"ENSG00000135776"	"ABCB10"	"hsa:23456; Q13040; Q6P1Q8; Q9H3V0; Q9NRK6"	"Mitochondrial ABC transporters"	""	"1"	"0"	"2.2"	"0.0"	"4.5"	"3.5"	"2.8"	"1.9"	"3.8"	"0.0"	"81.2"	"73.2"	"246.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DI83"	"Ras-related protein Rab-34, isoform NARR OS=Homo sapiens OX=9606 GN=RAB34 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"198"	"21.1"	"12.16"	"295.45"	"2.47"	"1"	"1"	""	"nucleus"	""	""	"83871"	"ENSG00000109113"	"RAB34"	"P0DI83"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9HAU4"	"E3 ubiquitin-protein ligase SMURF2 OS=Homo sapiens OX=9606 GN=SMURF2 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"748"	"86.1"	"7.96"	""	"2.47"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf00397, Pf00632"	"64750"	"ENSG00000108854"	"SMURF2"	"hsa:64750; Q52LL1; Q9H260; Q9HAU4"	"Ub-specific processing proteases; Antigen processing: Ubiquitination & Proteasome degradation; Asymmetric localization of PCP proteins; Degradation of AXIN; Hedgehog 'on' state; Regulation of RUNX3 expression and activity; Signaling by BMP; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity"	"Hedgehog signaling pathway"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXW9"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 OS=Homo sapiens OX=9606 GN=ALKBH4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"302"	"33.8"	"6.67"	"283.90"	"2.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"54784"	"ENSG00000160993"	"ALKBH4"	"hsa:54784; Q53H92; Q9H6A4; Q9NXW9"	""	""	"0"	"0"	"8.7"	"7.8"	"14.7"	"10.5"	"11.0"	"8.1"	"25.4"	"2.1"	"211.8"	"207.4"	"381.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H871"	"E3 ubiquitin-protein transferase RMND5A OS=Homo sapiens OX=9606 GN=RMND5A PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"391"	"44.0"	"6.06"	""	"2.46"	""	"1"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10607, Pf13445"	"64795"	"ENSG00000153561"	"RMND5A"	"D6W5M6; hsa:64795; Q6NTF0; Q9H6W5; Q9H871; Q9H9H2"	""	"Ciliary landscape"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKN8"	"General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"822"	"91.9"	"6.65"	"358.69"	"2.46"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12657, Pf12660, Pf19336"	"9329"	"ENSG00000125484"	"GTF3C4"	"hsa:9329; Q5VZJ7; Q9UKN8"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	""	"3"	"0"	"0.0"	"0.0"	"6.4"	"0.0"	"0.0"	"0.0"	"11.1"	"1.7"	"102.0"	"104.8"	"237.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXK0"	"Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"858"	"90.7"	"8.69"	"306.21"	"2.46"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536, Pf16616"	"1912"	"ENSG00000134686"	"PHC2"	"A1L4Q1; A8KA40; D3DPR2; hsa:1912; Q2TAL3; Q5T0C1; Q6NUJ6; Q6ZQR1; Q8IXK0; Q8N306; Q8TAG8; Q96BL4; Q9Y4Y7"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	""	"8"	"0"	"69.5"	"47.0"	"58.5"	"56.3"	"47.3"	"65.7"	"130.1"	"0.0"	"414.1"	"447.6"	"813.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WY36"	"HMG box transcription factor BBX OS=Homo sapiens OX=9606 GN=BBX PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"941"	"105.1"	"8.79"	"258.18"	"2.45"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09667"	"56987"	"ENSG00000114439"	"BBX"	"A2RRM7; hsa:56987; Q2TAJ1; Q7L3J8; Q7LBY8; Q8NDB0; Q8WY35; Q8WY36; Q9H0J6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P78316"	"Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"857"	"97.6"	"7.58"	""	"2.45"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04147"	"8602"	"ENSG00000087269"	"NOP14"	"D3DVR6; hsa:8602; P78316; Q7LGI5; Q7Z6K0; Q8TBR6"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"22.2"	"18.7"	"27.1"	"19.1"	"22.0"	"6.8"	"43.5"	"1.3"	"160.8"	"136.8"	"326.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5XG87"	"Terminal nucleotidyltransferase 4A OS=Homo sapiens OX=9606 GN=TENT4A PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"772"	"82.3"	"9.52"	""	"2.45"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"11.1"	"8.0"	"14.7"	"10.4"	"12.4"	"7.5"	"30.1"	"0.9"	"139.4"	"119.0"	"247.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPG3"	"Ubinuclein-1 OS=Homo sapiens OX=9606 GN=UBN1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1134"	"121.4"	"9.33"	"317.53"	"2.45"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf08729, Pf14075"	"29855"	"ENSG00000118900"	"UBN1"	"B7Z6D3; D3DUE8; hsa:29855; Q13079; Q9NPG3; Q9P1P7"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"15q11q13 copy number variation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P25789"	"Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"261"	"29.5"	"7.72"	""	"2.45"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5685"	"ENSG00000041357"	"PSMA4"	"D3DW86; hsa:5685; P25789; Q53XP2; Q567Q5; Q8TBD1"	"MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Exercise-induced circadian regulation; Alzheimer's disease"	"63"	"0"	"8.7"	"6.0"	"7.7"	"11.0"	"8.3"	"6.2"	"12.9"	"0.1"	"120.5"	"144.7"	"322.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BN2"	"Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"335"	"37.4"	"7.39"	"305.53"	"2.44"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12767"	"117143"	"ENSG00000152382"	"TADA1"	"A8K4J9; hsa:117143; Q96BN2"	"HATs acetylate histones"	""	"1"	"0"	"2.6"	"2.3"	"6.6"	"4.5"	"3.7"	"0.0"	"9.7"	"0.0"	"95.9"	"108.4"	"208.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWV7"	"E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens OX=9606 GN=UBR1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1749"	"200.1"	"6.01"	"225.54"	"2.44"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf02207, Pf02617, Pf18995"	"197131"	"ENSG00000159459"	"UBR1"	"hsa:197131; O60708; O75492; Q14D45; Q68DN9; Q8IWV7; Q8IWY6; Q96JY4"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	"6.0"	"5.8"	"7.0"	"6.7"	"2.7"	"3.9"	"11.6"	"1.4"	"47.7"	"56.9"	"60.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NWS0"	"PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"290"	"32.3"	"5.14"	""	"2.44"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08190, Pf18201"	"55011"	"ENSG00000104872"	"PIH1D1"	"B4DGN7; B4E2X7; hsa:55011; Q9BVL0; Q9NWS0"	""	""	"0"	"0"	"2.3"	"4.7"	"7.2"	"5.3"	"6.7"	"4.7"	"11.3"	"1.7"	"108.5"	"100.2"	"241.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95707"	"Ribonuclease P protein subunit p29 OS=Homo sapiens OX=9606 GN=POP4 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"220"	"25.4"	"10.07"	"325.90"	"2.44"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01868"	"10775"	"ENSG00000105171"	"POP4"	"hsa:10775; O95707; Q5XKL7; Q6FHW9; Q9UQQ3"	"tRNA processing in the nucleus"	""	"1"	"0"	"32.2"	"27.4"	"20.1"	"31.1"	"29.8"	"27.4"	"55.4"	"0.4"	"167.2"	"162.8"	"275.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2Y7"	"Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1"	"0.000"	""	"0"	"1"	"2"	"1"	"1883"	"208.8"	"7.15"	"307.77"	"2.44"	"1"	"1"	"signal transduction"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf00400"	"64397"	"ENSG00000103994"	"ZNF106"	"B4DZ40; E9PE29; hsa:64397; Q6NSD9; Q6PEK1; Q86T43; Q86T45; Q86T50; Q86T58; Q86TA9; Q96M37; Q9H2Y7; Q9H7B8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07093"	"Glia-derived nexin OS=Homo sapiens OX=9606 GN=SERPINE2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"398"	"44.0"	"9.29"	"454.15"	"2.44"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00079"	"5270"	"ENSG00000135919"	"SERPINE2"	"B2R6A4; B4DIF2; hsa:5270; P07093; Q53S15; Q5D0C4"	"Intrinsic Pathway of Fibrin Clot Formation; Common Pathway of Fibrin Clot Formation; Dissolution of Fibrin Clot"	""	"3"	"0"	"0.0"	"1.8"	"2.0"	"0.0"	"0.0"	"0.0"	"1.0"	"0.0"	"46.7"	"69.7"	"103.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y3C8"	"Ubiquitin-fold modifier-conjugating enzyme 1 OS=Homo sapiens OX=9606 GN=UFC1 PE=1 SV=3"	""	""	"5"	"1"	"1"	"1"	"167"	"19.4"	"7.40"	""	"2.43"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes"	""	"other molecular function"	"Pf08694"	"51506"	"ENSG00000143222"	"UFC1"	"A8K9R1; D3DVF9; hsa:51506; Q549X0; Q5VTX1; Q9BS96; Q9P009; Q9Y3C8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O15550"	"Lysine-specific demethylase 6A OS=Homo sapiens OX=9606 GN=KDM6A PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1401"	"154.1"	"7.44"	""	"2.43"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02373, Pf13181, Pf13432"	"7403"	"ENSG00000147050"	"KDM6A"	"hsa:7403; O15550; Q52LL9; Q5JVQ7"	"Formation of WDR5-containing histone-modifying complexes; Activation of anterior HOX genes in hindbrain development during early embryogenesis; HDMs demethylate histones"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Pathways affected in adenoid cystic carcinoma; Pleural mesothelioma; Kleefstra syndrome"	"8"	"0"	"3.9"	"7.0"	"5.6"	"4.3"	"2.1"	"8.6"	"9.0"	"0.8"	"56.0"	"53.0"	"105.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YQ0"	"Cytospin-A OS=Homo sapiens OX=9606 GN=SPECC1L PE=1 SV=2"	"0.000"	""	"1"	"2"	"2"	"1"	"1117"	"124.5"	"5.72"	"312.96"	"2.43"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H2E6"	"Semaphorin-6A OS=Homo sapiens OX=9606 GN=SEMA6A PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1030"	"114.3"	"8.41"	""	"2.43"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"3.2"	"2.1"	"3.7"	"3.2"	"3.5"	"3.4"	"4.8"	"0.0"	"42.6"	"41.6"	"82.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UGI8"	"Testin OS=Homo sapiens OX=9606 GN=TES PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"421"	"48.0"	"7.68"	""	"2.43"	""	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00412, Pf06297"	"26136"	"ENSG00000135269"	"TES"	"A4D0U6; hsa:26136; Q9GZQ1; Q9HAJ9; Q9UGI8"	""	""	"0"	"0"	"21.9"	"35.3"	"29.2"	"29.6"	"26.5"	"27.5"	"92.9"	"0.0"	"520.0"	"562.1"	"823.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2L9"	"Leucine-rich repeat and calponin homology domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LRCH1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"728"	"80.8"	"5.94"	"297.90"	"2.43"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf00307, Pf13855"	"23143"	"ENSG00000136141"	"LRCH1"	"B7ZLL5; F8W6F0; hsa:23143; Q17R43; Q2KHR1; Q5TBU9; Q7Z5F6; Q7Z5F7; Q9Y2L9"	""	""	"0"	"0"	"8.4"	"10.5"	"13.2"	"10.5"	"11.9"	"7.1"	"14.0"	"1.0"	"167.1"	"175.5"	"444.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NR09"	"Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"4857"	"529.9"	"6.05"	""	"2.42"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"2.1"	"0.0"	"0.0"	"2.7"	"0.0"	"110.2"	"89.6"	"359.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND04"	"Protein SMG8 OS=Homo sapiens OX=9606 GN=SMG8 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"991"	"109.6"	"7.68"	"276.61"	"2.42"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol"	""	"Pf10220"	"55181"	"ENSG00000167447"	"SMG8"	"hsa:55181; Q8N5U5; Q8ND04; Q8TDN0; Q9H5P5; Q9NVQ1"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75582"	"Ribosomal protein S6 kinase alpha-5 OS=Homo sapiens OX=9606 GN=RPS6KA5 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"802"	"89.8"	"7.11"	"250.64"	"2.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433"	"9252"	"ENSG00000100784"	"RPS6KA5"	"B7Z2Y5; hsa:9252; O75582; O95316; Q96AF7"	"Recycling pathway of L1; NCAM signaling for neurite out-growth; ERK/MAPK targets; CREB phosphorylation; CD209 (DC-SIGN) signaling"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Bladder cancer; MAPK signaling pathway; ERK pathway in Huntington's disease; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; p38 MAPK signaling pathway; EGF/EGFR signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Insulin signaling; Pleural mesothelioma; Hippocampal synaptogenesis and neurogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"22"	"0"	"0.0"	"0.0"	"3.7"	"0.0"	"0.0"	"2.7"	"3.6"	"2.0"	"57.8"	"58.0"	"118.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40818"	"Ubiquitin carboxyl-terminal hydrolase 8 OS=Homo sapiens OX=9606 GN=USP8 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1118"	"127.4"	"8.51"	"315.26"	"2.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00443, Pf00581, Pf08969"	"9101"	"ENSG00000138592"	"USP8"	"B4DKA8; hsa:9101; P40818; Q2TB31; Q7Z3U2; Q86VA0; Q8IWI7"	"Ub-specific processing proteases; Downregulation of ERBB2:ERBB3 signaling; Negative regulation of MET activity; Regulation of FZD by ubiquitination"	"EGF/EGFR signaling pathway; Male infertility"	"6"	"0"	"21.1"	"17.9"	"24.2"	"14.4"	"22.2"	"19.4"	"48.7"	"4.5"	"331.3"	"334.7"	"674.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DB5"	"Regulator of microtubule dynamics protein 1 OS=Homo sapiens OX=9606 GN=RMDN1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"314"	"35.8"	"8.50"	"225.34"	"2.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity"	""	"51115"	"ENSG00000176623"	"RMDN1"	"A9UMZ8; B4DNF5; B4DZW6; B5MC61; C9JSC6; E7EVI2; hsa:51115; Q96DB5; Q9Y398"	""	""	"0"	"0"	"0.0"	"3.5"	"0.0"	"0.0"	"0.0"	"2.5"	"1.3"	"0.0"	"30.3"	"32.2"	"65.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14012"	"Calcium/calmodulin-dependent protein kinase type 1 OS=Homo sapiens OX=9606 GN=CAMK1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"370"	"41.3"	"5.29"	""	"2.41"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8536"	"ENSG00000134072"	"CAMK1"	"hsa:8536; Q14012; Q3KPF6"	"Negative regulation of NMDA receptor-mediated neuronal transmission; Activation of RAC1 downstream of NMDARs"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Physico-chemical features and toxicity-associated pathways; Clear cell renal cell carcinoma pathways; Fragile X syndrome; CAMKK2 pathway; Calcium regulation in cardiac cells"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5VUG0"	"Scm-like with four MBT domains protein 2 OS=Homo sapiens OX=9606 GN=SFMBT2 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"894"	"100.5"	"6.55"	""	"2.41"	""	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00536, Pf02820, Pf12140"	"57713"	"ENSG00000198879"	"SFMBT2"	"A7MD09; hsa:57713; Q5VUG0; Q9HCF5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IWA4"	"Mitofusin-1 OS=Homo sapiens OX=9606 GN=MFN1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"741"	"84.1"	"6.33"	""	"2.41"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00350, Pf04799"	"55669"	"ENSG00000171109"	"MFN1"	"A0A0C4DFN1; B2RAR1; D3DNR6; hsa:55669; O15323; O60639; Q8IWA4; Q9BZB5; Q9NWQ2"	"Factors involved in megakaryocyte development and platelet production; PINK1-PRKN Mediated Mitophagy; RHOT2 GTPase cycle"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51946"	"Cyclin-H OS=Homo sapiens OX=9606 GN=CCNH PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"323"	"37.6"	"7.15"	"231.86"	"2.40"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"enzyme regulator activity"	"Pf00134, Pf16899"	"902"	"ENSG00000134480"	"CCNH"	"hsa:902; P51946; Q53X72; Q8TBL9"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"Cell cycle; Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"39"	"0"	"2.9"	"3.8"	"4.8"	"4.1"	"5.3"	"3.0"	"9.0"	"2.3"	"72.0"	"85.2"	"155.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P19823"	"Inter-alpha-trypsin inhibitor heavy chain H2 OS=Homo sapiens OX=9606 GN=ITIH2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"946"	"106.4"	"6.86"	""	"2.40"	""	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00092, Pf06668, Pf08487"	"3698"	"ENSG00000151655"	"ITIH2"	"hsa:3698; P19823; Q14659; Q15484; Q5T986"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTM9"	"Copper homeostasis protein cutC homolog OS=Homo sapiens OX=9606 GN=CUTC PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"273"	"29.3"	"8.18"	"266.06"	"2.40"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03932"	"51076"	"ENSG00000119929"	"CUTC"	"hsa:51076; Q5TCZ8; Q9NTM9; Q9Y321"	"Ion transport by P-type ATPases"	""	"1"	"0"	"21.4"	"12.6"	"17.7"	"19.2"	"23.2"	"17.4"	"32.1"	"1.6"	"218.9"	"199.5"	"386.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86U86"	"Protein polybromo-1 OS=Homo sapiens OX=9606 GN=PBRM1 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1689"	"192.8"	"6.89"	""	"2.40"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00505, Pf01426"	"55193"	"ENSG00000163939"	"PBRM1"	"A1L381; A1L382; A4FUJ7; hsa:55193; Q1RMD1; Q1RMD2; Q86U86; Q96MS2; Q9H2T3; Q9H2T4; Q9H2T5; Q9H301; Q9H314"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"Clear cell renal cell carcinoma pathways"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08AD1"	"Calmodulin-regulated spectrin-associated protein 2 OS=Homo sapiens OX=9606 GN=CAMSAP2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1489"	"168.0"	"6.80"	"240.76"	"2.39"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi"	"cytoskeletal activity;other molecular function"	"Pf08683, Pf11971, Pf17095"	"23271"	"ENSG00000118200"	"CAMSAP2"	"B1APG6; hsa:23271; Q08AD1; Q08AD2; Q6PGN8; Q96FB3; Q9UG20; Q9UPS4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13480"	"GRB2-associated-binding protein 1 OS=Homo sapiens OX=9606 GN=GAB1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"694"	"76.6"	"5.96"	"281.41"	"2.39"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00169"	"2549"	"ENSG00000109458"	"GAB1"	"A8K152; hsa:2549; Q13480; Q4W5G2; Q6P1W2"	"PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI3K Cascade; Signaling by FGFR1 in disease; PI-3K cascade:FGFR1; PI-3K cascade:FGFR2; Signaling by FGFR2 in disease; PI-3K cascade:FGFR3; PI-3K cascade:FGFR4; Signaling by FGFR3 in disease; MET activates RAP1 and RAC1; RET signaling; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); PI3K events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; GAB1 signalosome; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; MET activates PI3K/AKT signaling; MET activates PTPN11; MET receptor recycling; Activated NTRK2 signals through PI3K"	"Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Alpha 6 beta 4 signaling pathway; Hepatocyte growth factor receptor signaling; IL6 signaling pathway; BDNF-TrkB signaling; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; ErbB signaling pathway"	"45"	"0"	"11.9"	"13.8"	"9.9"	"15.3"	"10.1"	"18.0"	"38.5"	"0.7"	"312.4"	"284.7"	"404.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFT6"	"Protein DBF4 homolog B OS=Homo sapiens OX=9606 GN=DBF4B PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"615"	"67.2"	"8.34"	"253.96"	"2.39"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07535"	"80174"	"ENSG00000161692"	"DBF4B"	"D3DX56; hsa:80174; Q8NFT6; Q8TEX0; Q96B19; Q9H912"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2D0"	"Inhibitor of Bruton tyrosine kinase OS=Homo sapiens OX=9606 GN=IBTK PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1353"	"150.4"	"7.71"	"256.29"	"2.39"	"1"	"1"	"transport;other biological processes"	"other membranes;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf00651, Pf12796"	"25998"	"ENSG00000005700; ENSG00000283068"	"IBTK"	"hsa:25998; Q2QKU2; Q2QKU3; Q2QKU4; Q5TFD7; Q5TFD9; Q8IUQ9; Q8IUY7; Q8TAI4; Q9HBI8; Q9P2D0; Q9Y3T8"	""	"Genetic causes of porto-sinusoidal vascular disease"	"1"	"0"	"31.3"	"19.3"	"26.4"	"31.5"	"27.0"	"32.0"	"54.7"	"3.1"	"399.5"	"382.9"	"853.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WW8"	"Cytochrome c oxidase assembly factor 5 OS=Homo sapiens OX=9606 GN=COA5 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"74"	"8.4"	"8.68"	"284.19"	"2.39"	"1"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	"Pf10203"	"493753"	"ENSG00000183513"	"COA5"	"hsa:493753; Q86WW8"	""	""	"0"	"0"	"39.8"	"43.7"	"35.2"	"39.3"	"30.5"	"10.6"	"113.6"	"0.0"	"609.6"	"600.1"	"1137.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9T8"	"Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"703"	"82.5"	"5.14"	"377.94"	"2.39"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf05178, Pf12936"	"65095"	"ENSG00000129347"	"KRI1"	"hsa:65095; Q2M1R5; Q2M1R7; Q7L5J7; Q8N9T8; Q96G92; Q9BU50; Q9H6I1; Q9H978"	""	""	"0"	"0"	"40.3"	"32.2"	"43.8"	"38.7"	"37.3"	"40.6"	"106.9"	"2.7"	"183.2"	"179.6"	"277.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PE7"	"Methylmalonyl-CoA epimerase, mitochondrial OS=Homo sapiens OX=9606 GN=MCEE PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"176"	"18.7"	"9.09"	"221.68"	"2.38"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf13669"	"84693"	"ENSG00000124370"	"MCEE"	"hsa:84693; Q53TP1; Q8WW63; Q96PE7"	"Propionyl-CoA catabolism"	"Vitamin B12 metabolism"	"2"	"0"	"8.8"	"7.7"	"11.6"	"10.1"	"7.5"	"7.9"	"14.8"	"1.6"	"141.7"	"132.5"	"241.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VV42"	"Threonylcarbamoyladenosine tRNA methylthiotransferase OS=Homo sapiens OX=9606 GN=CDKAL1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"579"	"65.1"	"7.46"	"238.50"	"2.37"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00919, Pf01938, Pf04055"	"54901"	"ENSG00000145996"	"CDKAL1"	"A8K6S0; hsa:54901; Q5VV42; Q6P385; Q6ZR27; Q9NXB3"	"tRNA modification in the nucleus and cytosol"	"Vitamin D receptor pathway"	"2"	"0"	"5.2"	"4.8"	"5.7"	"5.0"	"3.5"	"6.6"	"10.4"	"0.1"	"59.1"	"63.6"	"109.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB19"	"Pleckstrin homology domain-containing family A member 2 OS=Homo sapiens OX=9606 GN=PLEKHA2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"425"	"47.2"	"8.66"	"530.89"	"2.37"	"2"	"1"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59339"	""	"PLEKHA2"	"hsa:59339; Q9HB19"	"Synthesis of PIPs at the plasma membrane"	""	"1"	"0"	"5.0"	"2.6"	"4.8"	"2.4"	"3.6"	"6.2"	"11.0"	"1.1"	"119.0"	"134.7"	"214.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NI08"	"Nuclear receptor coactivator 7 OS=Homo sapiens OX=9606 GN=NCOA7 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"942"	"106.1"	"5.59"	""	"2.37"	""	"1"	"stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf01476, Pf07534"	"135112"	"ENSG00000111912"	"NCOA7"	"B2RNS2; B7Z2C4; B9EH71; G8JL91; hsa:135112; Q3LID6; Q4G0V1; Q5TF95; Q6IPQ4; Q6NE83; Q86T89; Q8N1W4; Q8NI08"	""	"Aryl hydrocarbon receptor pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17706"	"Tyrosine-protein phosphatase non-receptor type 2 OS=Homo sapiens OX=9606 GN=PTPN2 PE=1 SV=2"	"0.000"	""	"4"	"2"	"2"	"2"	"415"	"48.4"	"8.29"	"224.58"	"2.37"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5771"	"ENSG00000175354"	"PTPN2"	"A8K955; A8MXU3; hsa:5771; K7ENG3; P17706; Q96AU5; Q96HR2"	"Negative regulation of MET activity; Interleukin-37 signaling"	"Immune response to tuberculosis; 5q35 copy number variation"	"4"	"0"	"13.5"	"14.2"	"15.5"	"16.6"	"15.2"	"14.6"	"48.1"	"10.3"	"548.0"	"1256.0"	"701.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95801"	"Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"387"	"44.7"	"5.60"	"276.65"	"2.37"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf18972"	"7268"	"ENSG00000243725"	"TTC4"	"hsa:7268; O95801; Q53Y95; Q5TA96; Q9H3I2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13886"	"Krueppel-like factor 9 OS=Homo sapiens OX=9606 GN=KLF9 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"244"	"27.2"	"8.51"	"280.26"	"2.36"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"687"	"ENSG00000119138"	"KLF9"	"B2R943; hsa:687; Q13886; Q16196"	""	"Exercise-induced circadian regulation; Familial partial lipodystrophy"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13144"	"Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens OX=9606 GN=EIF2B5 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"721"	"80.3"	"5.08"	""	"2.36"	""	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02020"	"8893"	"ENSG00000145191"	"EIF2B5"	"hsa:8893; Q13144; Q541Z1; Q96D04"	"Recycling of eIF2:GDP"	"Translation factors; MicroRNAs in cardiomyocyte hypertrophy; DYRK1A involvement regarding cell proliferation in brain development; Primary ovarian insufficiency"	"5"	"0"	"24.8"	"17.5"	"31.5"	"24.5"	"35.1"	"26.4"	"37.4"	"0.0"	"610.6"	"644.6"	"1696.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29374"	"AT-rich interactive domain-containing protein 4A OS=Homo sapiens OX=9606 GN=ARID4A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1257"	"142.7"	"5.10"	"359.52"	"2.36"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01388, Pf08169, Pf11717"	"5926"	"ENSG00000032219"	"ARID4A"	"hsa:5926; P29374; Q15991; Q15992; Q15993"	"Potential therapeutics for SARS; HDACs deacetylate histones"	""	"2"	"0"	"4.7"	"2.8"	"3.3"	"6.3"	"3.9"	"4.0"	"7.6"	"0.0"	"23.1"	"30.5"	"69.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y262"	"Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"564"	"66.7"	"6.34"	""	"2.35"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10255"	"51386"	"ENSG00000100129"	"EIF3L"	"B2RDG6; B4DYB2; G8JLH4; hsa:51386; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; Q9Y262"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	""	"6"	"0"	"14.9"	"8.8"	"13.6"	"12.3"	"11.7"	"15.8"	"35.9"	"0.0"	"394.5"	"419.6"	"1355.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y673"	"Dolichyl-phosphate beta-glucosyltransferase OS=Homo sapiens OX=9606 GN=ALG5 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"324"	"36.9"	"9.28"	"252.25"	"2.35"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00535"	"29880"	"ENSG00000120697"	"ALG5"	"B4DR37; hsa:29880; Q5TBA6; Q9Y673"	"Synthesis of dolichyl-phosphate-glucose"	"N-glycan biosynthesis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNW9"	"RNA-binding protein Nova-2 OS=Homo sapiens OX=9606 GN=NOVA2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"492"	"49.0"	"8.16"	"243.04"	"2.35"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"4858"	"ENSG00000104967"	"NOVA2"	"hsa:4858; O43267; Q9UEA1; Q9UNW9"	""	""	"0"	"0"	"57.1"	"51.1"	"58.2"	"51.4"	"58.3"	"59.8"	"148.2"	"0.0"	"340.3"	"350.3"	"486.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z7K0"	"COX assembly mitochondrial protein homolog OS=Homo sapiens OX=9606 GN=CMC1 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"106"	"12.5"	"8.63"	"316.08"	"2.35"	"1"	"1"	""	"mitochondrion"	"other molecular function"	"Pf08583"	"152100"	"ENSG00000187118"	"CMC1"	"hsa:152100; Q68DJ7; Q7Z7K0"	""	"Mitochondrial complex IV assembly"	"1"	"0"	"8.2"	"2.9"	"6.8"	"10.5"	"7.2"	"10.2"	"67.1"	"0.0"	"345.4"	"415.1"	"588.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y217"	"Myotubularin-related protein 6 OS=Homo sapiens OX=9606 GN=MTMR6 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"621"	"71.9"	"7.66"	""	"2.35"	""	"1"	"protein metabolism;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf06602"	"9107"	"ENSG00000139505"	"MTMR6"	"B2RBB5; B3KSB4; hsa:9107; Q5JRG6; Q86TB7; Q86YH4; Q96P80; Q9Y217"	"Synthesis of PIPs at the plasma membrane"	"8p23.1 copy number variation syndrome"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06400"	"Retinoblastoma-associated protein OS=Homo sapiens OX=9606 GN=RB1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"928"	"106.1"	"7.94"	"237.59"	"2.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01857, Pf01858, Pf08934, Pf11934"	"5925"	"ENSG00000139687"	"RB1"	"A8K5E3; hsa:5925; P06400; P78499; Q5VW46; Q8IZL4"	"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Oncogene Induced Senescence; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Aberrant regulation of mitotic exit in cancer due to RB1 defects; RUNX2 regulates osteoblast differentiation; Condensation of Prophase Chromosomes; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; Cyclin A:Cdk2-associated events at S phase entry; Formation of Senescence-Associated Heterochromatin Foci (SAHF); Inhibition of replication initiation of damaged DNA by RB1/E2F1; Defective translocation of RB1 mutants to the nucleus; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Adipogenesis; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Bladder cancer; Fas ligand pathway and stress induction of heat shock proteins; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; Tumor suppressor activity of SMARCB1; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; G1 to S cell cycle control; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Overlap between signal transduction pathways contributing to LMNA laminopathies; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sphingolipid metabolism in senescence; Prostaglandin and leukotriene metabolism in senescence ; ID signaling pathway; TROP2 regulatory signaling; Prostaglandin and leukotriene metabolism in senescence ; DNA damage response"	"47"	"0"	"25.4"	"21.9"	"25.2"	"26.9"	"21.8"	"23.0"	"53.7"	"3.2"	"329.6"	"337.0"	"523.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75691"	"Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"2785"	"318.2"	"7.39"	""	"2.34"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf07539, Pf20416"	"27340"	"ENSG00000120800"	"UTP20"	"hsa:27340; O75691; Q9H3H4"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"64.6"	"12.8"	"118.4"	"77.8"	"117.7"	"72.5"	"73.5"	"0.0"	"284.6"	"196.6"	"697.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y4C1"	"Lysine-specific demethylase 3A OS=Homo sapiens OX=9606 GN=KDM3A PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1321"	"147.2"	"8.07"	""	"2.34"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"55818"	"ENSG00000115548"	"KDM3A"	"D6W5M3; hsa:55818; Q53S72; Q68D47; Q68UT9; Q6N050; Q8IY08; Q9Y4C1"	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; HDMs demethylate histones"	"Thermogenesis; Male infertility; Vitamin D-sensitive calcium signaling in depression"	"5"	"0"	"6.2"	"5.4"	"11.6"	"5.6"	"12.6"	"10.6"	"15.9"	"0.9"	"56.3"	"76.3"	"101.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13394"	"Putative nucleotidyltransferase MAB21L1 OS=Homo sapiens OX=9606 GN=MAB21L1 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"359"	"40.9"	"8.66"	""	"2.33"	""	"1"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03281, Pf20266"	"4081"	"ENSG00000180660"	"MAB21L1"	"hsa:4081; Q13394; Q6I9T5"	""	""	"0"	"0"	"187.4"	"123.2"	"156.6"	"170.6"	"137.4"	"147.4"	"314.2"	"0.0"	"599.1"	"481.3"	"1171.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTE6"	"Alanyl-tRNA editing protein Aarsd1 OS=Homo sapiens OX=9606 GN=AARSD1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"412"	"45.5"	"6.42"	"288.72"	"2.33"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07973"	"100885850; 80755"	"ENSG00000108825; ENSG00000266967"	"AARSD1"	"B4DI73; hsa:100885850; hsa:80755; Q9BTE6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NS91"	"E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN=RAD18 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"495"	"56.2"	"7.58"	"231.14"	"2.33"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf13923"	"56852"	"ENSG00000070950"	"RAD18"	"hsa:56852; Q58F55; Q9NRT6; Q9NS91"	"E3 ubiquitin ligases ubiquitinate target proteins; Recognition of DNA damage by PCNA-containing replication complex"	"SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"3"	"0"	"59.5"	"29.7"	"47.8"	"44.6"	"60.2"	"39.2"	"66.1"	"0.0"	"309.4"	"273.0"	"649.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14924"	"Regulator of G-protein signaling 12 OS=Homo sapiens OX=9606 GN=RGS12 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1447"	"156.3"	"7.44"	"246.14"	"2.33"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00595, Pf00615, Pf02188, Pf02196, Pf16611, Pf16612, Pf16613"	"6002"	"ENSG00000159788"	"RGS12"	"B1AQ30; B1AQ31; B1AQ32; B7Z764; E7EMN9; hsa:6002; O14922; O14923; O14924; O43510; O75338; Q147X0; Q8WX95"	"G alpha (i) signalling events"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5L8"	"Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"163"	"17.6"	"10.30"	"303.02"	"2.33"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01918"	"138716"	"ENSG00000164967"	"RPP25L"	"D3DRM5; hsa:138716; Q8N5L8"	""	""	"0"	"0"	"22.1"	"7.3"	"35.2"	"21.3"	"21.6"	"20.3"	"71.7"	"0.0"	"187.0"	"170.6"	"329.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY31"	"Intraflagellar transport protein 20 homolog OS=Homo sapiens OX=9606 GN=IFT20 PE=1 SV=1"	"0.000"	""	"11"	"1"	"2"	"1"	"132"	"15.3"	"5.12"	"317.72"	"2.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf14931"	"90410"	"ENSG00000109083"	"IFT20"	"hsa:90410; J3QL09; Q5GLZ2; Q8IY31; Q9BUG5"	"Intraflagellar transport"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR)"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P54727"	"UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"409"	"43.1"	"4.84"	""	"2.33"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5887"	"ENSG00000119318"	"RAD23B"	"B3KWK8; G5E9P0; hsa:5887; P54727; Q7Z5K8; Q8WUB0"	"Josephin domain DUBs; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"7"	"0"	"83.5"	"74.7"	"80.4"	"83.5"	"81.3"	"89.4"	"151.5"	"0.0"	"421.0"	"424.5"	"687.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JUR7"	"Testis-expressed protein 30 OS=Homo sapiens OX=9606 GN=TEX30 PE=2 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"227"	"25.6"	"8.66"	"314.78"	"2.33"	"1"	"1"	""	""	""	"Pf20408"	"93081"	"ENSG00000151287"	"TEX30"	"hsa:93081; Q5JUR7; Q5JUR8; Q96KZ8"	""	""	"0"	"0"	"5.1"	"3.3"	"3.7"	"1.7"	"5.0"	"6.4"	"6.8"	"0.0"	"92.1"	"110.4"	"276.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15154"	"Pericentriolar material 1 protein OS=Homo sapiens OX=9606 GN=PCM1 PE=1 SV=5"	"0.000"	""	"0"	"1"	"2"	"1"	"2024"	"228.4"	"5.02"	"381.20"	"2.32"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15717"	"5108"	"ENSG00000078674"	"PCM1"	"A6NNN6; B4DYD5; E7ETA6; E7EV56; hsa:5108; Q15154; Q58F13; Q6P1K7; Q8NB85; Q9BWC1; Q9H4A2"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"Prader-Willi and Angelman syndrome; Joubert syndrome"	"9"	"0"	"23.5"	"21.5"	"15.3"	"20.3"	"15.9"	"16.7"	"29.2"	"1.1"	"142.0"	"136.9"	"270.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60563"	"Cyclin-T1 OS=Homo sapiens OX=9606 GN=CCNT1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"726"	"80.6"	"8.78"	"308.84"	"2.32"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00134"	"904"	"ENSG00000129315"	"CCNT1"	"A9XU13; E7EX76; hsa:904; O60563; O60581"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Interactions of Tat with host cellular proteins"	"Initiation of transcription and translation elongation at the HIV-1 LTR; Male infertility"	"17"	"0"	"33.7"	"24.3"	"29.7"	"32.9"	"31.9"	"31.7"	"87.7"	"2.1"	"383.8"	"368.1"	"834.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ04"	"Testis-specific Y-encoded-like protein 4 OS=Homo sapiens OX=9606 GN=TSPYL4 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"414"	"45.1"	"8.57"	"238.91"	"2.31"	"1"	"1"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"23270"	"ENSG00000187189"	"TSPYL4"	"B4DYQ2; hsa:23270; O94828; Q96GW8; Q9UJ04"	""	""	"0"	"0"	"10.4"	"8.2"	"5.0"	"9.3"	"8.4"	"7.8"	"13.9"	"1.9"	"42.0"	"39.7"	"63.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRY4"	"Rho GTPase-activating protein 35 OS=Homo sapiens OX=9606 GN=ARHGAP35 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1499"	"170.4"	"6.64"	"254.95"	"2.31"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"2909"	"ENSG00000160007"	"ARHGAP35"	"A7E2A4; hsa:2909; Q14452; Q9C0E1; Q9NRY4"	"RND3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RND2 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RND1 GTPase cycle; Sema4D mediated inhibition of cell attachment and migration; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"Focal adhesion; Regulation of actin cytoskeleton"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXW5"	"Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Homo sapiens OX=9606 GN=RPAP2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"612"	"69.5"	"7.78"	"306.61"	"2.30"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04181"	"79871"	"ENSG00000122484"	"RPAP2"	"C9JKB5; hsa:79871; Q49AS7; Q8IXW5; Q9H8Y2"	"RNA polymerase II transcribes snRNA genes"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14202"	"Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1370"	"152.3"	"6.35"	""	"2.30"	""	"1"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06467, Pf12012"	"9203"	"ENSG00000147130"	"ZMYM3"	"D3DVV3; hsa:9203; O15089; Q14202; Q96E26"	""	"Orexin receptor pathway"	"1"	"0"	"0.0"	"3.8"	"4.6"	"3.7"	"3.7"	"2.9"	"2.4"	"0.0"	"41.5"	"43.3"	"103.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JTZ9"	"Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"985"	"107.3"	"6.27"	"276.87"	"2.30"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf07973"	"57505"	"ENSG00000124608"	"AARS2"	"A2RRN5; hsa:57505; Q5JTZ9; Q8N198; Q96D02; Q9ULF0"	"Mitochondrial tRNA aminoacylation"	"Primary ovarian insufficiency"	"2"	"0"	"12.2"	"11.0"	"17.5"	"13.0"	"10.1"	"11.9"	"19.0"	"0.0"	"489.9"	"552.1"	"1042.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43847"	"Nardilysin OS=Homo sapiens OX=9606 GN=NRDC PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1151"	"131.6"	"4.98"	"232.20"	"2.30"	"1"	"1"	"protein metabolism;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00675, Pf05193, Pf16187"	"4898"	"ENSG00000078618"	"NRDC"	"A6NI41; hsa:4898; O15241; O15242; O43847; Q5VUL0; Q96HB2; Q9NU57"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TER0"	"Sushi, nidogen and EGF-like domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNED1 PE=2 SV=2"	""	""	"1"	"1"	"1"	"1"	"1413"	"152.1"	"6.98"	""	"2.30"	""	"1"	"cell adhesion"	"non-structural extracellular;extracellular matrix"	"signal transduction activity or receptor binding;other molecular function"	"Pf00008, Pf00041, Pf06119, Pf12661"	"25992"	"ENSG00000162804"	"SNED1"	"B5MDC3; B7WNK6; B7WPM0; hsa:25992; Q336F4; Q336F5; Q8N369; Q8TEP7; Q8TER0"	""	"2q37 copy number variation syndrome"	"1"	"0"	"71.1"	"46.6"	"61.3"	"68.7"	"47.1"	"62.8"	"118.5"	"0.0"	"220.6"	"187.9"	"453.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6DKI1"	"60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"2"	"2"	"255"	"29.7"	"10.52"	"530.68"	"2.30"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf00327, Pf08079"	"285855"	"ENSG00000146223"	"RPL7L1"	"A8K7D4; B7Z652; hsa:285855; Q5TFZ5; Q6DKI1; Q6PEK3"	""	""	"0"	"0"	"39.1"	"37.5"	"39.8"	"35.9"	"32.1"	"40.6"	"126.5"	"2.6"	"227.4"	"224.2"	"366.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NG48"	"Protein Lines homolog 1 OS=Homo sapiens OX=9606 GN=LINS1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"757"	"85.8"	"6.52"	""	"2.29"	""	"1"	"other biological processes"	""	""	"Pf14694, Pf14695"	"55180"	"ENSG00000140471"	"LINS1"	"hsa:55180; Q8NG48; Q96FW2; Q9NVQ3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXE9"	"Stonin-2 OS=Homo sapiens OX=9606 GN=STON2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"905"	"101.1"	"5.39"	"340.01"	"2.29"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00928, Pf12016"	"85439"	"ENSG00000140022"	"STON2"	"G3V2T7; hsa:85439; Q17R24; Q59H11; Q6NT47; Q8WXE9; Q96RI7; Q96RU6"	"Cargo recognition for clathrin-mediated endocytosis"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G01"	"Protein bicaudal D homolog 1 OS=Homo sapiens OX=9606 GN=BICD1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"975"	"110.7"	"5.81"	"251.78"	"2.29"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf09730"	"636"	"ENSG00000151746"	"BICD1"	"A8K2C3; F8W113; hsa:636; O43892; O43893; Q96G01"	"COPI-independent Golgi-to-ER retrograde traffic"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.7"	"2.1"	"0.0"	"28.7"	"32.6"	"66.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13905"	"Rap guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=RAPGEF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1077"	"120.5"	"5.92"	"294.95"	"2.29"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00617, Pf00618"	"2889"	"ENSG00000107263"	"RAPGEF1"	"hsa:2889; Q13905; Q5JUE4; Q68DL3; Q8IV73"	"RAC3 GTPase cycle; Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling; Interferon type I signaling pathways"	"16"	"0"	"0.0"	"0.0"	"2.2"	"0.0"	"0.0"	"0.0"	"5.9"	"0.0"	"93.8"	"107.5"	"168.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43482"	"Protein Mis18-beta OS=Homo sapiens OX=9606 GN=OIP5 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"229"	"24.7"	"7.37"	"311.26"	"2.28"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf03226"	"11339"	"ENSG00000104147"	"OIP5"	"hsa:11339; O43482; Q96BX7"	"Deposition of new CENPA-containing nucleosomes at the centromere"	""	"1"	"0"	"4.1"	"3.4"	"5.8"	"3.1"	"4.6"	"2.8"	"5.7"	"0.0"	"43.3"	"45.3"	"109.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NMY6"	"Putative annexin A2-like protein OS=Homo sapiens OX=9606 GN=ANXA2P2 PE=5 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"339"	"38.6"	"6.95"	"249.53"	"2.28"	"1"	"1"	"transport"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"transporter activity;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00191"	""	""	"ANXA2P2"	"A6NMY6"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.7"	"0.0"	"25.9"	"22.7"	"72.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43617"	"Trafficking protein particle complex subunit 3 OS=Homo sapiens OX=9606 GN=TRAPPC3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"180"	"20.3"	"4.96"	"265.15"	"2.28"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"27095"	"ENSG00000054116"	"TRAPPC3"	"A6NDN0; B2RDN2; D3DPS2; hsa:27095; O43617"	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	""	"2"	"0"	"12.2"	"10.8"	"16.8"	"12.2"	"11.9"	"11.3"	"22.6"	"0.0"	"166.4"	"165.1"	"367.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2X0"	"Mediator of RNA polymerase II transcription subunit 16 OS=Homo sapiens OX=9606 GN=MED16 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"877"	"96.7"	"7.37"	""	"2.27"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf11635"	"10025"	"ENSG00000175221"	"MED16"	"hsa:10025; Q6PJT2; Q96AD4; Q96I35; Q9Y2X0; Q9Y652"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BS16"	"Centromere protein K OS=Homo sapiens OX=9606 GN=CENPK PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"269"	"31.6"	"4.89"	""	"2.27"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;nucleus;other cell component"	""	"Pf11802"	"64105"	"ENSG00000123219"	"CENPK"	"hsa:64105; Q9BS16; Q9H4L0"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Deposition of new CENPA-containing nucleosomes at the centromere; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"7"	"0"	"3.1"	"1.9"	"2.6"	"2.0"	"4.2"	"0.0"	"5.4"	"3.7"	"120.0"	"86.5"	"315.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NDG6"	"ATP-dependent RNA helicase TDRD9 OS=Homo sapiens OX=9606 GN=TDRD9 PE=2 SV=3"	""	""	"1"	"1"	"1"	"1"	"1382"	"155.6"	"7.05"	""	"2.27"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00567, Pf04408"	"122402"	"ENSG00000156414"	"TDRD9"	"A1A4S7; hsa:122402; Q6ZU54; Q8N7T3; Q8N827; Q8N9V5; Q8NDG6; Q96AS9"	"PIWI-interacting RNA (piRNA) biogenesis"	""	"1"	"0"	"5.6"	"4.5"	"9.3"	"7.6"	"7.9"	"6.7"	"16.7"	"0.2"	"951.9"	"1074.1"	"2672.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCD3"	"Holliday junction recognition protein OS=Homo sapiens OX=9606 GN=HJURP PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"748"	"83.5"	"9.31"	"230.27"	"2.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10384, Pf12346, Pf12347"	"55355"	"ENSG00000123485"	"HJURP"	"A8IRH5; B4DWR0; B4DZV4; hsa:55355; Q8NCD3; Q9BUT2; Q9NSL8"	"Deposition of new CENPA-containing nucleosomes at the centromere"	"2q37 copy number variation syndrome"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRG0"	"Chromatin accessibility complex protein 1 OS=Homo sapiens OX=9606 GN=CHRAC1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"131"	"14.7"	"5.10"	"248.61"	"2.26"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"54108"	"ENSG00000104472"	"CHRAC1"	"hsa:54108; Q9NRG0"	""	"Acute viral myocarditis"	"1"	"0"	"21.6"	"18.6"	"20.8"	"25.1"	"21.9"	"17.9"	"25.4"	"0.0"	"189.9"	"204.9"	"429.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3P7"	"Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"528"	"60.6"	"5.06"	"232.86"	"2.26"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00887, Pf13897"	"64746"	"ENSG00000182827"	"ACBD3"	"B2RB29; hsa:64746; Q5VTJ0; Q6P9F1; Q8IZC5; Q8N4D6; Q9H3P7; Q9H6U3"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	"19.4"	"19.4"	"15.2"	"18.3"	"13.8"	"16.0"	"47.8"	"0.0"	"160.7"	"180.4"	"258.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9R8"	"Protein SCAI OS=Homo sapiens OX=9606 GN=SCAI PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"606"	"70.4"	"8.60"	"258.28"	"2.26"	"1"	"1"	"other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf12070"	"286205"	"ENSG00000173611"	"SCAI"	"hsa:286205; Q3SXZ1; Q3SXZ2; Q5T163; Q8N1I4; Q8N9R8"	"RHO GTPases Activate Formins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92888"	"Rho guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=ARHGEF1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"912"	"102.4"	"5.66"	"238.35"	"2.26"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity"	"Pf00621, Pf09128, Pf17838"	"9138"	"ENSG00000076928"	"ARHGEF1"	"hsa:9138; O00513; Q6NX52; Q8N4J4; Q92888; Q96BF4; Q96F17; Q9BSB1"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events"	"G protein signaling pathways; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"9"	"0"	"24.1"	"15.4"	"31.2"	"26.4"	"27.2"	"27.3"	"41.2"	"0.0"	"224.8"	"232.6"	"362.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Q9"	"28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"187"	"20.8"	"9.10"	"281.71"	"2.25"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10246"	"28957"	"ENSG00000147586"	"MRPS28"	"B2RDZ7; hsa:28957; Q96Q21; Q9Y2Q9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"68.2"	"50.1"	"71.6"	"70.8"	"67.9"	"67.3"	"105.4"	"0.0"	"422.8"	"380.0"	"837.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UGU5"	"HMG domain-containing protein 4 OS=Homo sapiens OX=9606 GN=HMGXB4 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"601"	"65.7"	"9.32"	""	"2.25"	""	"1"	"cell-cell signaling;transport;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf13775"	"10042"	"ENSG00000100281"	"HMGXB4"	"hsa:10042; O75672; O75673; Q9UGU5; Q9UMT5"	""	""	"0"	"0"	"4.7"	"4.8"	"8.9"	"4.7"	"11.1"	"6.7"	"12.4"	"2.4"	"55.7"	"66.8"	"93.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08379"	"Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"1002"	"113.0"	"5.02"	"947.47"	"2.25"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf15070, Pf19046"	"2801"	"ENSG00000167110"	"GOLGA2"	"A0A0C4DGS5; hsa:2801; Q08379; Q6GRM9; Q9BRB0; Q9NYF9"	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Golgi Cisternae Pericentriolar Stack Reorganization"	""	"4"	"0"	"4.5"	"2.3"	"7.1"	"7.1"	"5.0"	"4.2"	"13.0"	"0.0"	"235.8"	"246.0"	"507.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O15254"	"Peroxisomal acyl-coenzyme A oxidase 3 OS=Homo sapiens OX=9606 GN=ACOX3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"700"	"77.6"	"7.25"	""	"2.25"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770"	"8310"	"ENSG00000087008"	"ACOX3"	"hsa:8310; O15254; Q96AJ8"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14520"	"Hyaluronan-binding protein 2 OS=Homo sapiens OX=9606 GN=HABP2 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"560"	"62.6"	"6.54"	""	"2.25"	""	"1"	"cell adhesion;protein metabolism"	"non-structural extracellular"	"other molecular function"	"Pf00008, Pf00051, Pf00089"	"3026"	"ENSG00000148702"	"HABP2"	"A8K467; B7Z8U5; F5H5M6; hsa:3026; O00663; Q14520"	""	""	"0"	"0"	"28.3"	"27.2"	"31.6"	"20.9"	"23.9"	"26.2"	"57.6"	"0.0"	"289.2"	"291.9"	"632.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBZ4"	"DNA-(apurinic or apyrimidinic site) lyase 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"518"	"57.4"	"8.29"	"272.98"	"2.25"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372, Pf06839"	"27301"	"ENSG00000169188"	"APEX2"	"hsa:27301; Q9UBZ4; Q9Y5X7"	""	"Base excision repair; DNA repair pathways, full network"	"2"	"0"	"10.1"	"4.7"	"10.0"	"7.2"	"5.4"	"5.5"	"32.7"	"0.0"	"88.6"	"80.7"	"178.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14181"	"DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"598"	"65.9"	"5.24"	"233.87"	"2.25"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf04042, Pf08418"	"23649"	"ENSG00000014138"	"POLA2"	"B4DNB4; hsa:23649; Q14181; Q9BPV3"	"Activation of the pre-replicative complex; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"12"	"0"	"2.4"	"4.0"	"6.1"	"3.2"	"3.5"	"3.4"	"6.9"	"0.6"	"146.9"	"147.8"	"315.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75506"	"Heat shock factor-binding protein 1 OS=Homo sapiens OX=9606 GN=HSBP1 PE=1 SV=1"	""	""	"25"	"1"	"1"	"1"	"76"	"8.5"	"4.36"	""	"2.25"	""	"1"	"stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06825"	"3281"	"ENSG00000230989"	"HSBP1"	"hsa:3281; O75506; Q53XA8; Q7Z5Z3"	"HSF1 activation; Attenuation phase"	""	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4D8"	"Probable E3 ubiquitin-protein ligase HECTD4 OS=Homo sapiens OX=9606 GN=HECTD4 PE=1 SV=5"	"0.000"	""	"0"	"1"	"2"	"1"	"3996"	"439.1"	"6.19"	"307.76"	"2.25"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes"	"other molecular function"	"Pf00632"	""	""	"HECTD4"	"L8B0P6; Q3MJD5; Q6P0A0; Q7L530; Q8NB70; Q8WU73; Q96NT9; Q9NZS4; Q9UFT6; Q9Y4D8"	""	""	"0"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"28.9"	"54.0"	"96.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2KHR2"	"DNA-binding protein RFX7 OS=Homo sapiens OX=9606 GN=RFX7 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1363"	"146.8"	"6.76"	"229.70"	"2.24"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02257"	"64864"	"ENSG00000181827"	"RFX7"	"hsa:64864; Q2KHR2; Q6ZRR1; Q6ZTY6; Q8N3J0; Q9H7A9; Q9H956"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6M9"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"179"	"21.8"	"8.38"	"321.56"	"2.24"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4715"	"ENSG00000147684"	"NDUFB9"	"B2R8M6; hsa:4715; Q9UQE8; Q9Y6M9"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial immune response to SARS-CoV-2; Oxidative phosphorylation"	"6"	"0"	"30.1"	"22.9"	"41.8"	"35.5"	"30.0"	"37.1"	"51.2"	"2.4"	"382.6"	"439.2"	"754.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5J1"	"U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"556"	"62.0"	"8.76"	"308.34"	"2.24"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	""	"51096"	"ENSG00000011260"	"UTP18"	"hsa:51096; Q9H4N6; Q9Y5J1"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6X4"	"Soluble lamin-associated protein of 75 kDa OS=Homo sapiens OX=9606 GN=FAM169A PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"670"	"74.9"	"4.60"	"256.44"	"2.24"	"1"	"1"	""	"other membranes;nucleus"	""	""	"26049"	"ENSG00000198780"	"FAM169A"	"A8K1T9; hsa:26049; Q6MZT0; Q9H989; Q9Y6X4"	"RHOF GTPase cycle"	""	"1"	"0"	"12.9"	"9.8"	"14.1"	"11.5"	"14.6"	"14.8"	"14.3"	"0.0"	"245.8"	"288.2"	"661.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N392"	"Rho GTPase-activating protein 18 OS=Homo sapiens OX=9606 GN=ARHGAP18 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"663"	"74.9"	"6.44"	""	"2.24"	""	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity"	"Pf00620"	"93663"	"ENSG00000146376"	"ARHGAP18"	"E1P575; hsa:93663; Q58EZ3; Q6P679; Q6PJD7; Q8N392; Q96S64"	"RHOC GTPase cycle; RHOA GTPase cycle"	""	"2"	"0"	"3.0"	"0.0"	"0.0"	"4.0"	"0.0"	"1.8"	"11.2"	"0.0"	"126.9"	"159.3"	"199.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14677"	"Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"625"	"68.2"	"6.42"	"278.82"	"2.23"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"9685"	"ENSG00000113282"	"CLINT1"	"B7Z6F8; D3DQJ6; hsa:9685; Q14677; Q8NAF1; Q96E05"	"Golgi Associated Vesicle Biogenesis"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H900"	"Protein zwilch homolog OS=Homo sapiens OX=9606 GN=ZWILCH PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"591"	"67.2"	"6.27"	"220.91"	"2.22"	"1"	"1"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	""	"Pf09817"	"55055"	"ENSG00000174442"	"ZWILCH"	"B3KVB8; hsa:55055; Q6N049; Q8N404; Q96SY7; Q9H900; Q9NWG7"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	"5.1"	"0.0"	"5.7"	"3.3"	"5.7"	"5.9"	"4.8"	"0.8"	"81.1"	"80.9"	"188.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NY26"	"Zinc transporter ZIP1 OS=Homo sapiens OX=9606 GN=SLC39A1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"324"	"34.2"	"5.92"	""	"2.22"	""	"1"	"transport;developmental processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;transporter activity"	"Pf02535"	"27173"	"ENSG00000143570"	"SLC39A1"	"B4DDY7; hsa:27173; Q5T4K1; Q8N2H7; Q9BTV0; Q9NY26; Q9UBI7; Q9Y2Z7; Q9Y380"	"Zinc influx into cells by the SLC39 gene family"	"Nuclear receptors meta-pathway; NRF2 pathway; Zinc homeostasis"	"4"	"0"	"15.2"	"8.7"	"20.0"	"11.8"	"11.6"	"14.6"	"34.7"	"0.0"	"344.2"	"340.3"	"749.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42677"	"40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3"	"0.000"	""	"10"	"1"	"3"	"1"	"84"	"9.5"	"9.45"	"480.01"	"2.21"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01667"	"6232"	"ENSG00000177954"	"RPS27"	"hsa:6232; P42677; Q5T4L6"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"25"	"0"	"83.6"	"73.2"	"80.0"	"89.3"	"74.7"	"66.3"	"155.1"	"0.0"	"680.7"	"700.4"	"1224.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14832"	"Phytanoyl-CoA dioxygenase, peroxisomal OS=Homo sapiens OX=9606 GN=PHYH PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"338"	"38.5"	"8.47"	"228.79"	"2.21"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05721"	"5264"	"ENSG00000107537"	"PHYH"	"A8MTS8; B1ALH5; hsa:5264; O14832"	"TYSND1 cleaves peroxisomal proteins; Alpha-oxidation of phytanate"	""	"3"	"0"	"4.2"	"5.4"	"5.3"	"4.0"	"2.2"	"5.7"	"11.7"	"0.0"	"107.5"	"102.0"	"194.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4A0"	"Polypeptide N-acetylgalactosaminyltransferase 4 OS=Homo sapiens OX=9606 GN=GALNT4 PE=1 SV=2"	"0.000"	""	"4"	"2"	"2"	"1"	"578"	"66.6"	"7.61"	"228.92"	"2.21"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00535, Pf00652"	"100528030; 8693"	"ENSG00000257594"	"GALNT4"	"B2R775; B4DMX6; hsa:100528030; hsa:8693; O00208; Q8N4A0"	"O-linked glycosylation of mucins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P032"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"175"	"20.3"	"8.82"	"250.03"	"2.21"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf06784"	"29078"	"ENSG00000123545"	"NDUFAF4"	"B2R4J5; hsa:29078; Q9P032"	"Complex I biogenesis"	""	"1"	"0"	"57.5"	"50.3"	"56.5"	"54.3"	"59.3"	"46.2"	"103.5"	"0.0"	"1005.0"	"1001.0"	"1890.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UI10"	"Translation initiation factor eIF-2B subunit delta OS=Homo sapiens OX=9606 GN=EIF2B4 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"523"	"57.5"	"9.38"	"282.41"	"2.21"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01008"	"8890"	"ENSG00000115211"	"EIF2B4"	"hsa:8890; Q53RY7; Q5BJF4; Q9BUV9; Q9UBG4; Q9UI10; Q9UIQ9; Q9UJ95"	"Recycling of eIF2:GDP"	"Translation factors; Primary ovarian insufficiency"	"3"	"0"	"2.2"	"2.7"	"1.8"	"0.0"	"0.0"	"3.2"	"5.7"	"0.0"	"56.8"	"78.5"	"212.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ5"	"RNA-binding protein 41 OS=Homo sapiens OX=9606 GN=RBM41 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"413"	"47.1"	"8.70"	"295.16"	"2.20"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"55285"	"ENSG00000089682"	"RBM41"	"hsa:55285; Q5JSN7; Q5JSN8; Q96IZ5; Q9H8F7; Q9NV04"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NEJ9"	"Neuroguidin OS=Homo sapiens OX=9606 GN=NGDN PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"315"	"35.9"	"9.57"	""	"2.20"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf04000"	"25983"	"ENSG00000129460"	"NGDN"	"A8K760; hsa:25983; Q8NEJ9; Q9Y400"	""	""	"0"	"0"	"24.8"	"24.8"	"30.9"	"27.0"	"27.0"	"35.8"	"62.5"	"0.0"	"256.6"	"249.3"	"606.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y263"	"Phospholipase A-2-activating protein OS=Homo sapiens OX=9606 GN=PLAA PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"795"	"87.1"	"6.37"	"237.42"	"2.20"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400, Pf08324, Pf09070"	"9373"	"ENSG00000137055"	"PLAA"	"hsa:9373; Q53EU5; Q5VY33; Q9NUL8; Q9NVE9; Q9UF53; Q9Y263; Q9Y5L1"	""	""	"0"	"0"	"122.3"	"80.5"	"113.7"	"101.6"	"92.6"	"90.3"	"127.8"	"0.0"	"431.9"	"426.5"	"1324.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N1I0"	"Dedicator of cytokinesis protein 4 OS=Homo sapiens OX=9606 GN=DOCK4 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1966"	"225.1"	"7.65"	""	"2.20"	""	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf06920, Pf07653, Pf14429, Pf16172, Pf20421, Pf20422"	"9732"	"ENSG00000128512"	"DOCK4"	"hsa:9732; O14584; O94824; Q8N1I0; Q8NB45"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RHOG GTPase cycle; Factors involved in megakaryocyte development and platelet production"	""	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4T8"	"Carbonyl reductase family member 4 OS=Homo sapiens OX=9606 GN=CBR4 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"237"	"25.3"	"9.33"	"279.77"	"2.20"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf13561"	"84869"	"ENSG00000145439"	"CBR4"	"hsa:84869; Q8N4T8; Q8WTW8; Q96K93"	"Fatty acyl-CoA biosynthesis"	""	"1"	"0"	"23.8"	"21.9"	"33.1"	"21.8"	"30.1"	"29.2"	"72.2"	"0.0"	"207.4"	"233.7"	"393.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXC2"	"Glucose-fructose oxidoreductase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GFOD1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"390"	"43.1"	"5.92"	"262.04"	"2.20"	"1"	"1"	""	"non-structural extracellular"	"other molecular function"	"Pf01408, Pf02894"	"54438"	"ENSG00000145990"	"GFOD1"	"A8E4L6; hsa:54438; Q5T058; Q96JD4; Q9H5K2; Q9NXC2"	"RHOQ GTPase cycle"	""	"1"	"0"	"5.9"	"4.7"	"9.9"	"7.6"	"11.2"	"7.8"	"14.5"	"0.0"	"272.4"	"291.8"	"548.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6PJG2"	"Mitotic deacetylase-associated SANT domain protein OS=Homo sapiens OX=9606 GN=MIDEAS PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1045"	"114.9"	"9.19"	""	"2.20"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01448"	"91748"	"ENSG00000156030"	"MIDEAS"	"hsa:91748; Q6PJG2; Q6PK13; Q6PK59; Q6ZS23"	""	""	"0"	"0"	"8.9"	"7.3"	"8.3"	"8.7"	"8.5"	"10.8"	"16.1"	"0.0"	"290.0"	"316.4"	"747.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BPX3"	"Condensin complex subunit 3 OS=Homo sapiens OX=9606 GN=NCAPG PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1015"	"114.3"	"5.59"	""	"2.19"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf12719"	"64151"	"ENSG00000109805"	"NCAPG"	"hsa:64151; Q3MJE0; Q96SV9; Q9BPX3; Q9BUR3; Q9BVY1; Q9H914; Q9H9Z6; Q9HBI9"	"Condensation of Prometaphase Chromosomes"	""	"1"	"0"	"173.1"	"101.6"	"133.5"	"158.4"	"139.0"	"128.9"	"157.6"	"0.0"	"927.1"	"834.4"	"2044.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7L1I2"	"Synaptic vesicle glycoprotein 2B OS=Homo sapiens OX=9606 GN=SV2B PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"683"	"77.4"	"5.44"	""	"2.19"	""	"1"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity"	"Pf00083, Pf07690, Pf13599"	"9899"	"ENSG00000185518"	"SV2B"	"B4DH30; C6G489; hsa:9899; O94840; Q6IAR8; Q7L1I2"	"Toxicity of botulinum toxin type A (botA); Toxicity of botulinum toxin type D (botD); Toxicity of botulinum toxin type F (botF); Toxicity of botulinum toxin type E (botE)"	""	"4"	"0"	"7.1"	"0.0"	"5.4"	"2.1"	"6.3"	"5.4"	"6.5"	"0.0"	"220.1"	"196.5"	"375.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXI9"	"Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"593"	"65.2"	"9.70"	"252.00"	"2.19"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"57459"	"ENSG00000143614; ENSG00000261992"	"GATAD2B"	"D3DUZ2; hsa:57459; Q5VUR2; Q7LG68; Q8WXI9; Q9ULS0"	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	""	"6"	"0"	"84.6"	"53.3"	"85.0"	"76.2"	"58.0"	"68.2"	"96.8"	"0.0"	"330.7"	"315.6"	"722.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94854"	"Uncharacterized protein KIAA0754 OS=Homo sapiens OX=9606 GN=KIAA0754 PE=2 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1291"	"135.1"	"4.21"	"237.74"	"2.19"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWD1"	"Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"397"	"41.3"	"6.92"	"275.06"	"2.19"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"39"	"ENSG00000120437"	"ACAT2"	"B7Z233; E1P5B1; hsa:39; Q16146; Q5TCL7; Q8TDM4; Q9BWD1"	"Cholesterol biosynthesis"	"Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"6"	"0"	"4.5"	"3.8"	"8.0"	"0.0"	"0.0"	"2.9"	"8.8"	"0.0"	"20.0"	"26.0"	"43.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q67FW5"	"UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like protein 1 OS=Homo sapiens OX=9606 GN=B3GNTL1 PE=2 SV=2"	""	""	"2"	"1"	"1"	"1"	"361"	"40.7"	"7.40"	""	"2.18"	""	"1"	""	""	"other molecular function"	"Pf00535"	"146712"	"ENSG00000175711; ENSG00000277033"	"B3GNTL1"	"hsa:146712; Q67FW5; Q6GV30; Q8WUT3"	"O-linked glycosylation of mucins"	""	"1"	"0"	"19.1"	"14.8"	"13.1"	"15.1"	"14.0"	"23.2"	"47.5"	"0.0"	"326.8"	"344.3"	"427.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q3ZCT1"	"Zinc finger protein 260 OS=Homo sapiens OX=9606 GN=ZNF260 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"412"	"47.2"	"9.07"	""	"2.18"	""	"1"	""	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf13912"	"339324"	"ENSG00000254004"	"ZNF260"	"hsa:339324; Q0VF43; Q3ZCT1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HBE1"	"POZ-, AT hook-, and zinc finger-containing protein 1 OS=Homo sapiens OX=9606 GN=PATZ1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"687"	"74.0"	"8.35"	"234.72"	"2.18"	"1"	"1"	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf00651, Pf13894, Pf13912, Pf16637"	"23598"	"ENSG00000100105"	"PATZ1"	"hsa:23598; Q9HBE1; Q9HBE2; Q9HBE3; Q9P1A9; Q9UDU0; Q9Y529"	""	"Androgen receptor signaling pathway"	"1"	"0"	"14.3"	"7.6"	"13.8"	"12.5"	"10.1"	"9.2"	"19.7"	"1.5"	"67.6"	"52.1"	"135.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ70"	"Transcription factor 25 OS=Homo sapiens OX=9606 GN=TCF25 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"676"	"76.6"	"6.35"	"305.50"	"2.17"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04910"	"22980"	"ENSG00000141002"	"TCF25"	"hsa:22980; Q2MK75; Q9BQ70; Q9UPV3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P28072"	"Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4"	""	""	"4"	"1"	"1"	"1"	"239"	"25.3"	"4.92"	""	"2.17"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5694"	"ENSG00000142507"	"PSMB6"	"hsa:5694; P28072; Q96J55"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"8.5"	"8.5"	"10.5"	"6.3"	"10.6"	"10.1"	"13.2"	"0.0"	"65.7"	"65.0"	"135.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96RW7"	"Hemicentin-1 OS=Homo sapiens OX=9606 GN=HMCN1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"5635"	"613.0"	"6.49"	""	"2.17"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"extracellular matrix;plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00090, Pf07474, Pf07645, Pf07679, Pf12662, Pf13927"	"83872"	"ENSG00000143341"	"HMCN1"	"A6NGE3; hsa:83872; Q5TYR7; Q96DN3; Q96DN8; Q96RW7; Q96SC3"	""	""	"0"	"0"	"7.5"	"6.5"	"9.8"	"10.8"	"7.9"	"7.6"	"17.4"	"0.0"	"160.9"	"161.3"	"278.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2Q5"	"Ragulator complex protein LAMTOR2 OS=Homo sapiens OX=9606 GN=LAMTOR2 PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"125"	"13.5"	"5.40"	""	"2.17"	""	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf03259"	"28956"	"ENSG00000116586"	"LAMTOR2"	"hsa:28956; Q5VY97; Q5VY98; Q5VY99; Q9Y2Q5"	"Neutrophil degranulation; MAP2K and MAPK activation; Amino acids regulate mTORC1; Regulation of PTEN gene transcription; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK"	""	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14191"	"Werner syndrome ATP-dependent helicase OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1432"	"162.4"	"6.34"	"461.87"	"2.17"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00570, Pf01612, Pf09382, Pf14493, Pf16124"	"7486"	"ENSG00000165392"	"WRN"	"A1KYY9; hsa:7486; Q14191"	"SUMOylation of DNA damage response and repair proteins; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Holliday Junction Intermediates; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Removal of the Flap Intermediate from the C-strand"	"Non-homologous end joining; DNA repair pathways, full network; Progeria-associated lipodystrophy; Primary ovarian insufficiency"	"21"	"0"	"4.1"	"0.0"	"0.0"	"4.5"	"3.1"	"0.0"	"7.7"	"0.0"	"27.7"	"31.2"	"59.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14578"	"Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"2027"	"231.3"	"6.57"	"263.21"	"2.16"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00780"	"11113"	"ENSG00000122966"	"CIT"	"hsa:11113; O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RHO GTPases activate CIT"	"Pleural mesothelioma; G13 signaling pathway"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53HL2"	"Borealin OS=Homo sapiens OX=9606 GN=CDCA8 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"280"	"31.3"	"9.86"	"239.42"	"2.16"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf10444, Pf10512"	"55143"	"ENSG00000134690"	"CDCA8"	"D3DPT4; hsa:55143; Q53HL2; Q53HN1; Q96AM3; Q9NVW5"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; SUMOylation of DNA replication proteins"	""	"7"	"0"	"8.3"	"0.0"	"5.0"	"5.3"	"5.0"	"5.7"	"13.5"	"0.0"	"42.3"	"50.4"	"80.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NUP7"	"Serine/threonine-protein phosphatase 4 regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PPP4R4 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"873"	"99.4"	"7.80"	"252.89"	"2.16"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	""	"57718"	"ENSG00000119698; ENSG00000278326"	"PPP4R4"	"hsa:57718; Q6NUP7; Q9BUF8; Q9HCF0"	""	"16p11.2 proximal deletion syndrome"	"1"	"0"	"30.6"	"27.0"	"26.6"	"27.3"	"23.8"	"17.8"	"46.1"	"2.8"	"488.1"	"545.4"	"1127.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWI9"	"MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4"	"0.000"	""	"0"	"1"	"2"	"1"	"3065"	"336.0"	"6.90"	"248.37"	"2.16"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010, Pf00907, Pf16059"	"23269"	"ENSG00000174197"	"MGA"	"B9EGR5; E7ENI0; F5H7K2; hsa:23269; Q8IWI9; Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9"	"Transcriptional Regulation by E2F6"	"Pathways affected in adenoid cystic carcinoma"	"2"	"0"	"60.0"	"44.9"	"50.8"	"48.0"	"34.4"	"49.3"	"112.0"	"0.0"	"432.3"	"430.9"	"760.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJW0"	"Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"460"	"52.3"	"7.34"	"255.06"	"2.15"	"1"	"1"	""	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf05502"	"51164"	"ENSG00000132912"	"DCTN4"	"B3KWW0; D3DQH0; E5RGT5; hsa:51164; Q8TAN8; Q9UJW0"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; MHC class II antigen presentation; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	""	"4"	"0"	"0.0"	"0.0"	"5.7"	"0.0"	"1.7"	"0.0"	"1.3"	"0.0"	"78.5"	"88.1"	"231.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15927"	"Replication protein A 32 kDa subunit OS=Homo sapiens OX=9606 GN=RPA2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"270"	"29.2"	"6.15"	"221.12"	"2.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08784"	"6118"	"ENSG00000117748"	"RPA2"	"hsa:6118; P15927; Q52II0; Q5TEI9; Q5TEJ5"	"Regulation of HSF1-mediated heat shock response; Fanconi Anemia Pathway; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"miRNA regulation of DNA damage response; Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair; DNA damage response"	"38"	"0"	"97.6"	"83.1"	"128.3"	"119.5"	"113.6"	"99.9"	"158.7"	"0.0"	"686.8"	"637.2"	"1464.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54198"	"Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1017"	"111.8"	"8.07"	"253.42"	"2.14"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf07569"	"7290"	"ENSG00000100084"	"HIRA"	"hsa:7290; P54198; Q05BU9; Q8IXN2"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"22q11.2 copy number variation syndrome; 16p11.2 proximal deletion syndrome"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BYC9"	"39S ribosomal protein L20, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL20 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"149"	"17.4"	"10.86"	""	"2.14"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00453"	"55052"	"ENSG00000242485"	"MRPL20"	"B2RE41; B7Z746; hsa:55052; Q9BYC9"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"1p36 copy number variation syndrome"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96FS4"	"Signal-induced proliferation-associated protein 1 OS=Homo sapiens OX=9606 GN=SIPA1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"1042"	"112.1"	"6.60"	""	"2.14"	""	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity"	"Pf00595, Pf02145"	"6494"	"ENSG00000213445"	"SIPA1"	"hsa:6494; O14518; O60484; O60618; Q2YD83; Q96FS4"	"Rap1 signalling"	"MAPK cascade"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62508"	"Estrogen-related receptor gamma OS=Homo sapiens OX=9606 GN=ESRRG PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"458"	"51.3"	"6.48"	"290.61"	"2.14"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00104, Pf00105"	"2104"	"ENSG00000196482"	"ESRRG"	"A8K4I0; A8K6I2; B3KY84; E9PGB7; F8W8J3; hsa:2104; O75454; O96021; P62508; Q68DA0; Q6P274; Q6PK28; Q6TS38; Q9R1F3; Q9UNJ4"	"Nuclear Receptor transcription pathway"	""	"1"	"0"	"3.6"	"4.4"	"5.8"	"9.8"	"8.2"	"6.1"	"10.5"	"0.5"	"84.5"	"93.3"	"204.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2G2"	"Caspase recruitment domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CARD8 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"431"	"48.9"	"5.22"	""	"2.14"	""	"1"	"other biological processes"	"other cell component"	""	"Pf00619, Pf13553"	""	""	"CARD8"	"A0A024QZD3"	""	""	"0"	"0"	"6.9"	"3.9"	"9.3"	"4.8"	"7.6"	"7.3"	"18.0"	"0.0"	"81.1"	"94.1"	"166.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95671"	"Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein OS=Homo sapiens OX=9606 GN=ASMTL PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"621"	"68.8"	"6.07"	"248.17"	"2.14"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00891, Pf02545, Pf16864"	"8623"	"ENSG00000169093"	"ASMTL"	"B4DX75; F5GXH4; hsa:8623; J3JS33; O95671; Q5JQ53; Q8NBH5; Q96G02; Q9BUL6"	""	""	"0"	"0"	"2.6"	"0.0"	"5.8"	"0.0"	"3.0"	"4.7"	"5.1"	"0.0"	"45.6"	"51.3"	"129.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96HC4"	"PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5"	""	""	"2"	"1"	"1"	"1"	"596"	"63.9"	"8.21"	""	"2.13"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"10611"	"ENSG00000163110"	"PDLIM5"	"A8K6F9; D6RB78; E9PBF5; hsa:10611; O60705; Q56VN4; Q5UW38; Q8WVK0; Q96HC4"	"Neurexins and neuroligins"	"Extracellular vesicles in the crosstalk of cardiac cells"	"2"	"0"	"27.9"	"20.7"	"31.1"	"32.6"	"28.7"	"33.0"	"64.4"	"3.6"	"479.4"	"436.2"	"992.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13418"	"Integrin-linked protein kinase OS=Homo sapiens OX=9606 GN=ILK PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"452"	"51.4"	"8.07"	"221.26"	"2.13"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf07714, Pf12796"	"3611"	"ENSG00000166333"	"ILK"	"B7Z1I0; B7Z418; D3DQU0; hsa:3611; P57043; Q13418; Q68DZ3"	"Localization of the PINCH-ILK-PARVIN complex to focal adhesions"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; PPAR signaling pathway; Eukaryotic transcription initiation; Endometrial cancer; Acute viral myocarditis; Genes controlling nephrogenesis; Development of ureteric collection system; 2q37 copy number variation syndrome"	"13"	"0"	"25.8"	"23.8"	"32.6"	"30.0"	"26.4"	"24.2"	"35.7"	"0.0"	"424.0"	"426.7"	"784.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5TCS8"	"Adenylate kinase 9 OS=Homo sapiens OX=9606 GN=AK9 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1911"	"221.3"	"5.01"	""	"2.13"	""	"1"	"other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"221264"	"ENSG00000155085"	"AK9"	"A6NL75; B2RDJ0; B6ZDM7; hsa:221264; Q3MIS4; Q5I0W8; Q5TCS8; Q6ZNF1; Q6ZVR7; Q8N7C6; Q8WW00; Q96NF4"	"Interconversion of nucleotide di- and triphosphates"	""	"1"	"0"	"0.0"	"6.4"	"9.6"	"6.2"	"1.8"	"5.0"	"7.5"	"4.7"	"377.0"	"399.9"	"962.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P19174"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens OX=9606 GN=PLCG1 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1290"	"148.4"	"6.05"	""	"2.13"	""	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00387, Pf00388"	"5335"	"ENSG00000124181"	"PLCG1"	"B7ZLY7; B9EGH4; E1P5W4; hsa:5335; P19174; Q2V575"	"ISG15 antiviral mechanism; Role of phospholipids in phagocytosis; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Generation of second messenger molecules; Signaling by ALK fusions and activated point mutants; RET signaling; Downstream signal transduction; Signaling by ALK; DAP12 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; EGFR interacts with phospholipase C-gamma; Signaling by FGFR1 in disease; Synthesis of IP3 and IP4 in the cytosol; Phospholipase C-mediated cascade: FGFR1; Phospholipase C-mediated cascade; FGFR2; Signaling by FGFR2 in disease; VEGFR2 mediated cell proliferation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; Signaling by FGFR3 in disease; DAG and IP3 signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Role of second messengers in netrin-1 signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; PLCG1 events in ERBB2 signaling; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; PLC-gamma1 signalling; PECAM1 interactions; Activated NTRK2 signals through PLCG1; Activated NTRK3 signals through PLCG1"	"Angiogenesis; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; PDGF pathway; Primary focal segmental glomerulosclerosis (FSGS); T cell receptor and co-stimulatory signaling; Myometrial relaxation and contraction pathways; Kit receptor signaling pathway; MFAP5-mediated ovarian cancer cell motility and invasiveness; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; GPR40 pathway; Ras signaling; Non-small cell lung cancer; EGF/EGFR signaling pathway; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; mBDNF and proBDNF regulation of GABA neurotransmission; Modulators of TCR signaling and T cell activation; CCL18 signaling pathway; Th17 cell differentiation pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; ErbB signaling pathway; T-cell receptor signaling pathway"	"73"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43739"	"Cytohesin-3 OS=Homo sapiens OX=9606 GN=CYTH3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"400"	"46.3"	"5.47"	"224.29"	"2.13"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01369"	"9265"	"ENSG00000008256"	"CYTH3"	"A4D2N8; hsa:9265; O43739"	"Intra-Golgi traffic"	"Insulin signaling; 2q37 copy number variation syndrome"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75600"	"2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial OS=Homo sapiens OX=9606 GN=GCAT PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"419"	"45.3"	"8.05"	""	"2.13"	""	"1"	"other metabolic processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00155"	"23464"	"ENSG00000100116"	"GCAT"	"E2QC23; hsa:23464; O75600; Q6ZWF1; Q96CA9"	"Threonine catabolism"	""	"1"	"0"	"25.1"	"16.8"	"55.0"	"36.3"	"27.2"	"17.4"	"40.5"	"0.0"	"247.8"	"235.1"	"691.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX90"	"Spindle and kinetochore-associated protein 3 OS=Homo sapiens OX=9606 GN=SKA3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"412"	"46.3"	"5.11"	"235.68"	"2.13"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;cytoskeleton;other cell component"	""	""	"221150"	"ENSG00000165480"	"SKA3"	"A2A330; A2A331; B2RBY2; hsa:221150; Q5VZV5; Q86WR2; Q8IX90; Q8NBG1; Q96D22"	""	""	"0"	"0"	"0.0"	"3.3"	"4.4"	"6.5"	"4.2"	"3.4"	"10.4"	"2.1"	"45.2"	"37.2"	"65.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6P1L8"	"39S ribosomal protein L14, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL14 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"145"	"15.9"	"10.24"	""	"2.13"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00238"	"64928"	"ENSG00000180992"	"MRPL14"	"B2R575; hsa:64928; Q6P1L8; Q96Q72"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"3.3"	"3.7"	"6.5"	"3.0"	"1.6"	"8.2"	"13.4"	"0.4"	"61.9"	"64.7"	"121.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14534"	"Squalene monooxygenase OS=Homo sapiens OX=9606 GN=SQLE PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"574"	"63.9"	"8.63"	""	"2.12"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf08491, Pf13450"	"6713"	"ENSG00000104549"	"SQLE"	"hsa:6713; Q14534; Q9UEK6; Q9UNR6"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"Cholesterol biosynthesis pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Statin inhibition of cholesterol production; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"9"	"0"	"63.3"	"59.8"	"68.7"	"55.7"	"70.7"	"71.9"	"107.0"	"0.0"	"304.0"	"273.5"	"478.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07203"	"Glutathione peroxidase 1 OS=Homo sapiens OX=9606 GN=GPX1 PE=1 SV=4"	"0.000"	""	"8"	"1"	"2"	"1"	"203"	"22.1"	"6.55"	"234.41"	"2.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00255"	"2876"	"ENSG00000233276"	"GPX1"	"E9PAS1; hsa:2876; P07203; Q7Z5H1; Q9BW12"	"Detoxification of Reactive Oxygen Species; Synthesis of 15-eicosatetraenoic acid derivatives; Synthesis of 12-eicosatetraenoic acid derivatives; Synthesis of 5-eicosatetraenoic acids"	"Glutathione metabolism; Selenium micronutrient network; Folate metabolism; Amyotrophic lateral sclerosis (ALS); Trans-sulfuration, one-carbon metabolism and related pathways; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; TYROBP causal network in microglia; Oxidative stress response; Male infertility; p53 transcriptional gene network"	"15"	"0"	"5.5"	"5.7"	"5.7"	"5.6"	"6.7"	"1.8"	"12.5"	"3.3"	"133.7"	"81.9"	"291.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYY8"	"FAST kinase domain-containing protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=FASTKD2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"710"	"81.4"	"8.05"	"292.90"	"2.12"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"nucleic acid binding activity"	"Pf06743, Pf08368, Pf08373"	"22868"	"ENSG00000118246"	"FASTKD2"	"hsa:22868; Q9NVX6; Q9NYY8; Q9Y2H7"	""	""	"0"	"0"	"8.2"	"6.3"	"8.8"	"9.9"	"7.8"	"7.7"	"10.7"	"0.0"	"224.5"	"262.4"	"686.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43264"	"Centromere/kinetochore protein zw10 homolog OS=Homo sapiens OX=9606 GN=ZW10 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"779"	"88.8"	"6.27"	"229.61"	"2.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06248"	"9183"	"ENSG00000086827"	"ZW10"	"A1A528; hsa:9183; O43264"	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"7"	"0"	"9.2"	"7.9"	"13.1"	"12.8"	"11.2"	"7.4"	"17.1"	"0.0"	"198.8"	"251.3"	"375.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5SZK8"	"FRAS1-related extracellular matrix protein 2 OS=Homo sapiens OX=9606 GN=FREM2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"3169"	"350.9"	"5.03"	""	"2.12"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P85037"	"Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"733"	"75.4"	"9.32"	"381.41"	"2.12"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00250, Pf00498"	"221937"	"ENSG00000164916"	"FOXK1"	"hsa:221937; P85037"	"UCH proteinases"	""	"1"	"0"	"11.8"	"7.1"	"7.1"	"6.1"	"9.8"	"9.5"	"9.8"	"0.8"	"66.8"	"48.4"	"199.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T5Y3"	"Calmodulin-regulated spectrin-associated protein 1 OS=Homo sapiens OX=9606 GN=CAMSAP1 PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"1"	"1602"	"177.9"	"6.73"	"483.51"	"2.12"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08683, Pf11971, Pf17095"	"157922"	"ENSG00000130559"	"CAMSAP1"	"A1L4L2; B2REB2; B2REB3; hsa:157922; Q5T5Y3; Q70W33; Q8NCY0; Q96E80; Q96FM3; Q9UFJ5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y620"	"DNA repair and recombination protein RAD54B OS=Homo sapiens OX=9606 GN=RAD54B PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"910"	"102.9"	"8.12"	"229.08"	"2.12"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"25788"	"ENSG00000197275"	"RAD54B"	"F6WBS8; hsa:25788; Q9Y620"	""	"Homologous recombination; DNA repair pathways, full network"	"2"	"0"	"29.0"	"25.5"	"26.8"	"25.0"	"22.2"	"25.4"	"45.1"	"0.0"	"466.5"	"489.7"	"958.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TDR2"	"Serine/threonine-protein kinase 35 OS=Homo sapiens OX=9606 GN=STK35 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"534"	"58.0"	"9.74"	""	"2.12"	""	"1"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"140901"	"ENSG00000125834"	"STK35"	"B2RBM3; C7ENV8; hsa:140901; Q2NKW6; Q5T3R1; Q5T3R2; Q8TDR2; Q96AB4; Q9BZ06"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15434"	"RNA-binding motif, single-stranded-interacting protein 2 OS=Homo sapiens OX=9606 GN=RBMS2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"407"	"43.9"	"9.07"	"233.93"	"2.11"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"5939"	"ENSG00000076067"	"RBMS2"	"hsa:5939; Q15434"	""	""	"0"	"0"	"45.5"	"26.1"	"35.6"	"34.1"	"33.5"	"37.7"	"56.0"	"0.0"	"130.9"	"149.3"	"196.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BPU6"	"Dihydropyrimidinase-related protein 5 OS=Homo sapiens OX=9606 GN=DPYSL5 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"564"	"61.4"	"7.20"	""	"2.11"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01979"	"56896"	"ENSG00000157851"	"DPYSL5"	"hsa:56896; Q8TCL6; Q9BPU6; Q9NQC4; Q9NRY9"	"CRMPs in Sema3A signaling"	""	"1"	"0"	"15.9"	"11.5"	"16.1"	"10.9"	"15.3"	"17.1"	"32.5"	"6.0"	"368.1"	"360.5"	"749.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZ21"	"Phosphatase and actin regulator 4 OS=Homo sapiens OX=9606 GN=PHACTR4 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"702"	"78.2"	"6.62"	"314.15"	"2.10"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf02755"	"65979"	"ENSG00000204138"	"PHACTR4"	"A2APK6; B9ZVW0; D3DPM3; hsa:65979; Q68DD4; Q6NUN6; Q8IZ21; Q8N384; Q9H395; Q9H6X0; Q9H8W6"	""	""	"0"	"0"	"2.4"	"5.3"	"2.1"	"4.0"	"2.7"	"3.7"	"10.1"	"0.0"	"109.9"	"89.4"	"176.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WZ42"	"Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4"	"0.000"	""	"0"	"2"	"2"	"1"	"34350"	"3813.7"	"6.35"	"250.01"	"2.10"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00041, Pf00069, Pf02818, Pf07679, Pf09042, Pf18362"	"7273"	"ENSG00000155657"	"TTN"	"A6NKB1; E7EQE6; E7ET18; hsa:7273; K7ENY1; Q10465; Q10466; Q15598; Q2XUS3; Q32Q60; Q4U1Z6; Q4ZG20; Q6NSG0; Q6PDB1; Q6PJP0; Q7KYM2; Q7KYN4; Q7KYN5; Q7LDM3; Q7Z2X3; Q8TCG8; Q8WZ42; Q8WZ51; Q8WZ52; Q8WZ53; Q8WZB3; Q92761; Q92762; Q9UD97; Q9UP84; Q9Y6L9"	"Platelet degranulation ; Striated Muscle Contraction"	"Striated muscle contraction pathway; Cardiomyocyte signaling pathways converging on Titin"	"4"	"0"	"48.6"	"35.4"	"22.0"	"28.3"	"23.5"	"36.4"	"157.1"	"0.0"	"779.9"	"835.5"	"1131.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NE18"	"Putative methyltransferase NSUN7 OS=Homo sapiens OX=9606 GN=NSUN7 PE=2 SV=4"	""	""	"1"	"1"	"1"	"1"	"718"	"81.0"	"8.75"	""	"2.10"	""	"1"	"other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	"Pf01189"	"79730"	"ENSG00000179299"	"NSUN7"	"C9JI19; hsa:79730; Q8N9K8; Q8NE18; Q9H815"	""	""	"0"	"0"	"13.3"	"2.2"	"25.9"	"12.8"	"11.2"	"12.5"	"43.7"	"7.8"	"856.8"	"562.2"	"1935.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPJ8"	"NTF2-related export protein 2 OS=Homo sapiens OX=9606 GN=NXT2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"142"	"16.2"	"5.48"	"256.25"	"2.09"	"1"	"1"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	""	"Pf02136"	"55916"	"ENSG00000101888"	"NXT2"	"D3DUY1; hsa:55916; Q0VAN8; Q5JYV5; Q5JYV6; Q5JYV7; Q9H8U0; Q9NPJ8; Q9NQ64; Q9NRL7; Q9Y3M4; Q9Y3M5"	""	""	"0"	"0"	"29.5"	"23.2"	"40.7"	"30.2"	"32.1"	"29.6"	"181.7"	"0.0"	"478.4"	"496.6"	"945.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IUX1"	"Complex I assembly factor TMEM126B, mitochondrial OS=Homo sapiens OX=9606 GN=TMEM126B PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"230"	"25.9"	"8.81"	""	"2.09"	""	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf07114"	"55863"	"ENSG00000171204"	"TMEM126B"	"A8K535; A8MSS0; hsa:55863; Q32Q09; Q8IUX1; Q8WVU3; Q96EP3; Q9NZ29"	"Complex I biogenesis"	""	"1"	"0"	"8.7"	"7.7"	"11.7"	"11.1"	"9.1"	"7.8"	"22.0"	"0.8"	"499.0"	"408.5"	"629.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H808"	"Transducin-like enhancer protein 6 OS=Homo sapiens OX=9606 GN=TLE6 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"572"	"63.4"	"6.15"	""	"2.09"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	""	"79816"	"ENSG00000104953"	"TLE6"	"hsa:79816; J3KMZ1; Q9H808"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"G2XKQ0"	"Small ubiquitin-related modifier 5 OS=Homo sapiens OX=9606 GN=SUMO1P1 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"101"	"11.5"	"5.52"	""	"2.08"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11976"	""	""	"SUMO1P1"	"G2XKQ0"	""	""	"0"	"0"	"74.0"	"55.5"	"106.0"	"85.4"	"76.8"	"76.0"	"141.6"	"0.0"	"369.7"	"348.5"	"740.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3C0"	"Activating signal cointegrator 1 complex subunit 3 OS=Homo sapiens OX=9606 GN=ASCC3 PE=1 SV=3"	"0.000"	""	"1"	"2"	"2"	"2"	"2202"	"251.3"	"7.09"	"221.73"	"2.08"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf02889"	"10973"	"ENSG00000112249"	"ASCC3"	"E7EW23; hsa:10973; O43738; Q4G1A0; Q5VTN2; Q8N3C0; Q9H1I9; Q9H5A2; Q9NTR0"	"ALKBH3 mediated reversal of alkylation damage"	"Mesodermal commitment pathway; VEGFA-VEGFR2 signaling"	"3"	"0"	"2.1"	"3.5"	"4.0"	"3.2"	"3.5"	"5.4"	"5.3"	"0.0"	"191.6"	"221.1"	"539.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BTE1"	"Dynactin subunit 5 OS=Homo sapiens OX=9606 GN=DCTN5 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"182"	"20.1"	"8.02"	""	"2.08"	""	"1"	"developmental processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	""	"84516"	"ENSG00000166847"	"DCTN5"	"A8K9X8; H3BN51; H3BQA4; hsa:84516; Q9BTE1"	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	""	"4"	"0"	"13.8"	"4.7"	"19.3"	"11.5"	"18.4"	"15.5"	"20.1"	"1.2"	"86.8"	"95.4"	"203.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UBM7"	"7-dehydrocholesterol reductase OS=Homo sapiens OX=9606 GN=DHCR7 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"475"	"54.5"	"8.70"	""	"2.08"	""	"1"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf01222"	"1717"	"ENSG00000172893"	"DHCR7"	"B2R6Z2; hsa:1717; O60492; O60717; Q9UBM7"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis via desmosterol; Cholesterol biosynthesis via lathosterol"	"Vitamin D metabolism; Cholesterol biosynthesis pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"10"	"0"	"206.8"	"165.1"	"255.0"	"225.6"	"220.1"	"217.3"	"324.1"	"0.0"	"564.1"	"552.5"	"883.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P53803"	"DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"58"	"7.0"	"9.06"	""	"2.08"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03604"	"5440"	"ENSG00000147669"	"POLR2K"	"hsa:5440; P53803; Q6IBD4"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; Activation of anterior HOX genes in hindbrain development during early embryogenesis; mRNA Splicing - Major Pathway; Cytosolic sensors of pathogen-associated DNA ; Viral Messenger RNA Synthesis; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Inhibition of DNA recombination at telomere"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"57"	"0"	"67.0"	"54.9"	"70.4"	"77.9"	"79.1"	"70.6"	"112.3"	"0.0"	"598.7"	"553.2"	"918.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00387"	"NADH-cytochrome b5 reductase 3 OS=Homo sapiens OX=9606 GN=CYB5R3 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"301"	"34.2"	"7.59"	""	"2.08"	""	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00175, Pf00970"	"1727"	"ENSG00000100243"	"CYB5R3"	"B1AHF2; B7Z7L3; hsa:1727; O75675; P00387; Q8TDL8; Q8WTS8; Q9UEN4; Q9UEN5; Q9UL55; Q9UL56"	"Phase I - Functionalization of compounds; Neutrophil degranulation; Vitamin C (ascorbate) metabolism"	"Oxidation by cytochrome P450"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IVH2"	"Forkhead box protein P4 OS=Homo sapiens OX=9606 GN=FOXP4 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"680"	"73.4"	"6.40"	""	"2.08"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00250, Pf16159"	"116113"	"ENSG00000137166"	"FOXP4"	"hsa:116113; Q5W098; Q7Z7F8; Q8IVH2; Q8IW55; Q96E19"	""	""	"0"	"0"	"10.2"	"3.0"	"11.9"	"12.4"	"11.4"	"9.4"	"9.7"	"0.0"	"189.9"	"143.4"	"492.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q03518"	"Antigen peptide transporter 1 OS=Homo sapiens OX=9606 GN=TAP1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"808"	"87.2"	"8.02"	""	"2.08"	""	"1"	"transport;other biological processes"	"other membranes"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"6890"	""	"TAP1"	"A0A0S2Z5A6; hsa:6890"	""	"Type II interferon signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H1I8"	"Activating signal cointegrator 1 complex subunit 2 OS=Homo sapiens OX=9606 GN=ASCC2 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"757"	"86.3"	"5.16"	""	"2.07"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02845"	"84164"	"ENSG00000100325"	"ASCC2"	"B7Z8E0; F5H6J9; hsa:84164; Q4TT54; Q8TAZ0; Q9H1I8; Q9H711; Q9H9D6"	"ALKBH3 mediated reversal of alkylation damage"	""	"1"	"0"	"2.4"	"0.0"	"4.2"	"2.8"	"0.0"	"1.9"	"5.8"	"1.3"	"46.4"	"45.8"	"111.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95479"	"GDH/6PGL endoplasmic bifunctional protein OS=Homo sapiens OX=9606 GN=H6PD PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"791"	"88.8"	"7.30"	""	"2.07"	""	"1"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00479, Pf01182, Pf02781"	"9563"	"ENSG00000049239"	"H6PD"	"hsa:9563; O95479; Q4TT33; Q66I35; Q68DT3; R4GMU1"	""	"Classical pathway of steroidogenesis with glucocorticoid and mineralocorticoid metabolism"	"1"	"0"	"0.0"	"3.4"	"5.8"	"3.3"	"6.9"	"0.0"	"6.5"	"0.0"	"49.7"	"41.1"	"102.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95759"	"TBC1 domain family member 8 OS=Homo sapiens OX=9606 GN=TBC1D8 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1140"	"130.8"	"5.52"	"241.42"	"2.07"	"1"	"1"	"other biological processes"	"other membranes"	"enzyme regulator activity"	"Pf00566, Pf02893"	"11138"	"ENSG00000204634"	"TBC1D8"	"A6NDL4; A8K9W1; B9A6K4; hsa:11138; O95759; Q53SQ4; Q9UQ32"	""	""	"0"	"0"	"15.7"	"9.1"	"18.1"	"14.9"	"22.2"	"22.2"	"52.1"	"0.0"	"476.2"	"495.0"	"658.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14653"	"Interferon regulatory factor 3 OS=Homo sapiens OX=9606 GN=IRF3 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"427"	"47.2"	"5.34"	""	"2.07"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00605, Pf10401"	"3661"	"ENSG00000126456"	"IRF3"	"A8K7L2; B2RAZ3; hsa:3661; Q14653; Q5FBY1; Q5FBY2; Q5FBY4; Q7Z5G6"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Interferon gamma signaling; Interferon alpha/beta signaling; Negative regulators of DDX58/IFIH1 signaling; TICAM1-dependent activation of IRF3/IRF7; SARS-CoV-1 activates/modulates innate immune responses; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production; IRF3 mediated activation of type 1 IFN"	"Apoptosis; TLR4 signaling and tolerance; Toll-like receptor signaling related to MyD88; Novel intracellular components of RIG-I-like receptor pathway; Fibrin complement receptor 3 signaling pathway; White fat cell differentiation; Ebola virus infection in host; Measles virus infection; Cytosolic DNA-sensing pathway; Hepatitis B infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; SARS coronavirus and innate immunity; STING pathway in Kawasaki-like disease and COVID-19; Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; Urotensin-II-mediated signaling pathway; Induction of autophagy and toll-like receptor signaling pathways by graphene oxide ; Toll-like receptor signaling pathway"	"36"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y5G9"	"Protocadherin gamma-A4 OS=Homo sapiens OX=9606 GN=PCDHGA4 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"962"	"103.9"	"4.96"	""	"2.07"	""	"1"	"cell adhesion;developmental processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00028, Pf08266, Pf15974, Pf16492"	"56111"	"ENSG00000262576"	"PCDHGA4"	"A0A087WT05; A0A087WTI2; hsa:56111; Q9Y5D3; Q9Y5G9"	""	""	"0"	"0"	"13.9"	"8.3"	"14.5"	"14.3"	"18.3"	"13.0"	"29.0"	"0.0"	"940.5"	"720.2"	"2729.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P02671"	"Fibrinogen alpha chain OS=Homo sapiens OX=9606 GN=FGA PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"866"	"94.9"	"6.01"	""	"2.06"	""	"1"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00147, Pf08702, Pf12160"	"2243"	"ENSG00000171560"	"FGA"	"A8K3E4; D3DP14; D3DP15; hsa:2243; P02671; Q4QQH7; Q9BX62; Q9UCH2"	"Amyloid fiber formation; ER-Phagosome pathway; Integrin cell surface interactions; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; MyD88:MAL(TIRAP) cascade initiated on plasma membrane; MyD88 deficiency (TLR2/4); IRAK4 deficiency (TLR2/4); Regulation of TLR by endogenous ligand; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Common Pathway of Fibrin Clot Formation; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"Selenium micronutrient network; Folate metabolism; Blood clotting cascade; Complement system; VEGFA-VEGFR2 signaling; Fibrin complement receptor 3 signaling pathway; COVID-19, thrombosis and anticoagulation; Network map of SARS-CoV-2 signaling pathway"	"29"	"0"	"79.1"	"52.7"	"72.8"	"68.2"	"73.2"	"74.3"	"214.9"	"0.0"	"509.0"	"442.3"	"897.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14782"	"Kinesin-like protein KIF3C OS=Homo sapiens OX=9606 GN=KIF3C PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"793"	"89.4"	"8.22"	""	"2.06"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"266.9"	"205.8"	"244.8"	"235.2"	"233.7"	"235.0"	"257.4"	"0.0"	"705.8"	"756.7"	"1179.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBZ6"	"tRNA methyltransferase 10 homolog A OS=Homo sapiens OX=9606 GN=TRMT10A PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"339"	"39.7"	"7.65"	"771.38"	"2.06"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"93587"	"ENSG00000145331"	"TRMT10A"	"B2R8X7; hsa:93587; Q8TBZ6; Q9Y2T9"	"tRNA modification in the nucleus and cytosol"	""	"1"	"0"	"54.4"	"34.0"	"40.9"	"43.8"	"51.6"	"49.1"	"62.7"	"0.0"	"287.7"	"300.6"	"532.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NUV9"	"GTPase IMAP family member 4 OS=Homo sapiens OX=9606 GN=GIMAP4 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"329"	"37.5"	"7.81"	""	"2.05"	""	"1"	""	"cytosol;other cell component"	"other molecular function"	"Pf04548"	"55303"	"ENSG00000133574"	"GIMAP4"	"hsa:55303; Q9NUV9"	""	""	"0"	"0"	"19.3"	"17.7"	"26.5"	"21.8"	"22.6"	"41.5"	"94.8"	"0.0"	"379.0"	"406.0"	"653.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A0A0U1RR37"	"Uncharacterized protein C1orf232 OS=Homo sapiens OX=9606 GN=C1orf232 PE=4 SV=1"	""	""	"4"	"1"	"1"	"1"	"186"	"20.3"	"4.65"	""	"2.05"	""	"1"	""	""	""	""	""	"ENSG00000282872"	"C1orf232"	"A0A0U1RR37"	""	""	"0"	"0"	"14.9"	"15.2"	"27.3"	"14.5"	"16.3"	"15.7"	"32.9"	"0.0"	"789.1"	"857.5"	"2130.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NSV4"	"Protein diaphanous homolog 3 OS=Homo sapiens OX=9606 GN=DIAPH3 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1193"	"136.8"	"7.03"	""	"2.05"	""	"1"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"81624"	"ENSG00000139734"	"DIAPH3"	"A2A3B8; A2A3B9; A2A3C0; hsa:81624; Q18P99; Q18PA0; Q18PA1; Q2KPB6; Q3ZK23; Q5JTP8; Q5T2S7; Q5XKF6; Q6MZF0; Q6NUP0; Q86VS4; Q8NAV4; Q9NSV4"	"RHO GTPases Activate Formins; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle; RAC3 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle"	"Regulation of actin cytoskeleton"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51956"	"Serine/threonine-protein kinase Nek3 OS=Homo sapiens OX=9606 GN=NEK3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"506"	"57.7"	"7.17"	""	"2.05"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"4752"	"ENSG00000136098"	"NEK3"	"A8K2J4; hsa:4752; P51956; Q5TAP2; Q8J023; Q8WUN5"	""	"Prolactin signaling pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UHN1"	"DNA polymerase subunit gamma-2, mitochondrial OS=Homo sapiens OX=9606 GN=POLG2 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"485"	"54.9"	"8.35"	""	"2.05"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf03129"	"11232"	"ENSG00000256525"	"POLG2"	"hsa:11232; O00419; Q0IJ81; Q96GW2; Q9UHN1; Q9UK35; Q9UK94"	"Transcriptional activation of mitochondrial biogenesis"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.7"	"0.0"	"22.6"	"30.9"	"58.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1X5"	"Transcription initiation factor TFIID subunit 2 OS=Homo sapiens OX=9606 GN=TAF2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1199"	"136.9"	"8.19"	"231.14"	"2.05"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"6873"	"ENSG00000064313"	"TAF2"	"B2RE82; hsa:6873; O43487; O43604; O60668; Q6P1X5; Q86WW7; Q8IWK4"	"Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	""	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P59780"	"AP-3 complex subunit sigma-2 OS=Homo sapiens OX=9606 GN=AP3S2 PE=2 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"193"	"22.0"	"5.22"	"233.47"	"2.05"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01217"	"10239"	"ENSG00000157823"	"AP3S2"	"B2R677; B4DGQ3; hsa:10239; O09077; O09149; P59780; Q53H83; Q99589"	""	""	"0"	"0"	"38.9"	"30.8"	"48.0"	"36.2"	"33.0"	"42.8"	"95.1"	"0.0"	"728.9"	"795.6"	"1357.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96B01"	"RAD51-associated protein 1 OS=Homo sapiens OX=9606 GN=RAD51AP1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"352"	"38.4"	"9.11"	"563.63"	"2.05"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf15696"	"10635"	"ENSG00000111247"	"RAD51AP1"	"A8K7D3; hsa:10635; O43403; Q7Z779; Q96B01"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Homologous DNA Pairing and Strand Exchange; Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2"	""	"8"	"0"	"6.5"	"2.4"	"7.3"	"10.6"	"13.2"	"6.1"	"16.2"	"3.5"	"109.7"	"95.2"	"160.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P0DN79"	"Cystathionine beta-synthase-like protein OS=Homo sapiens OX=9606 GN=CBSL PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"551"	"60.5"	"6.65"	""	"2.04"	""	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00291, Pf00571"	"102724560; 875"	"ENSG00000160200"	"CBS"	"B2R993; D3DSK4; hsa:102724560; hsa:875; P35520; Q99425; Q9BWC5"	"Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate-alcohol and cancer pathway hypotheses; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Vitamin D receptor pathway; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis; Ciliary landscape"	"13"	"0"	"2.4"	"0.0"	"3.4"	"2.8"	"4.6"	"2.6"	"6.2"	"1.1"	"57.1"	"56.4"	"158.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05783"	"Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"1"	"430"	"48.0"	"5.45"	"498.92"	"2.04"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00038"	"3875"	"ENSG00000111057"	"KRT18"	"hsa:3875; P05783; Q53G38; Q5U0N8; Q9BW26"	"Formation of the cornified envelope"	"Pathogenic Escherichia coli infection"	"3"	"0"	"4.0"	"4.7"	"6.1"	"3.9"	"1.5"	"2.2"	"25.1"	"2.5"	"65.9"	"71.4"	"124.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5CZC0"	"Fibrous sheath-interacting protein 2 OS=Homo sapiens OX=9606 GN=FSIP2 PE=2 SV=4"	""	""	"0"	"1"	"1"	"1"	"6907"	"780.1"	"6.71"	""	"2.04"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	""	"Pf15783"	"401024"	"ENSG00000188738"	"FSIP2"	"hsa:401024; Q53TL3; Q53TN5; Q5CZC0; Q5HYH2; Q6ZTZ5; Q6ZU14; Q6ZU21"	""	""	"0"	"0"	"34.4"	"22.6"	"32.9"	"34.2"	"34.1"	"25.3"	"56.0"	"0.0"	"670.5"	"661.7"	"1424.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15573"	"TATA box-binding protein-associated factor RNA polymerase I subunit A OS=Homo sapiens OX=9606 GN=TAF1A PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"450"	"52.6"	"9.10"	""	"2.04"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity"	"Pf14929"	"9015"	"ENSG00000143498"	"TAF1A"	"B2RDZ8; D3DTB7; hsa:9015; Q15573; Q9NWA1"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Escape; SIRT1 negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Transcription Termination"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60762"	"Dolichol-phosphate mannosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=DPM1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"260"	"29.6"	"9.57"	""	"2.04"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00535"	"8813"	"ENSG00000000419"	"DPM1"	"hsa:8813; O15157; O60762; Q6IB78; Q96HK0"	"Synthesis of dolichyl-phosphate mannose; Defective DPM1 causes DPM1-CDG; Defective DPM3 causes DPM3-CDG; Defective DPM2 causes DPM2-CDG"	"VEGFA-VEGFR2 signaling; N-glycan biosynthesis"	"6"	"0"	"0.0"	"0.0"	"2.5"	"0.0"	"0.0"	"3.4"	"7.0"	"1.0"	"34.3"	"43.8"	"62.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEW8"	"Partitioning defective 3 homolog B OS=Homo sapiens OX=9606 GN=PARD3B PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1205"	"132.4"	"8.37"	"706.03"	"2.04"	"2"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00595, Pf12053"	"117583"	"ENSG00000116117"	"PARD3B"	"E9PE87; hsa:117583; Q8IUC7; Q8IUC9; Q8TEW8; Q96DK9; Q96N09; Q96NX6; Q96NX7; Q96Q29"	""	""	"0"	"0"	"8.9"	"8.1"	"9.2"	"3.8"	"7.9"	"10.5"	"20.5"	"0.0"	"428.7"	"429.4"	"956.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15120"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial OS=Homo sapiens OX=9606 GN=PDK3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"406"	"46.9"	"8.37"	"254.33"	"2.03"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion;nucleus"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5165"	"ENSG00000067992"	"PDK3"	"B4DXG6; hsa:5165; Q15120"	"Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	""	"2"	"0"	"16.8"	"14.3"	"22.2"	"22.0"	"16.0"	"16.3"	"26.0"	"0.0"	"197.2"	"191.6"	"424.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98082"	"Disabled homolog 2 OS=Homo sapiens OX=9606 GN=DAB2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"770"	"82.4"	"5.53"	"223.27"	"2.03"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00640"	"1601"	"ENSG00000153071"	"DAB2"	"A6NES5; hsa:1601; P98082; Q13598; Q9BTY0; Q9UK04"	"Cargo recognition for clathrin-mediated endocytosis; Formation of annular gap junctions"	"Endoderm differentiation"	"5"	"0"	"3.5"	"0.0"	"3.1"	"3.0"	"2.1"	"5.0"	"8.4"	"0.0"	"36.6"	"46.6"	"40.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P54687"	"Branched-chain-amino-acid aminotransferase, cytosolic OS=Homo sapiens OX=9606 GN=BCAT1 PE=1 SV=3"	""	""	"5"	"1"	"1"	"1"	"386"	"42.9"	"5.30"	""	"2.03"	""	"1"	"cell cycle OR cell proliferation;other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf01063"	"586"	"ENSG00000060982"	"BCAT1"	"B3KY27; B7Z2M5; B7Z5L0; F5H5E4; hsa:586; P54687; Q68DQ7; Q96MY9"	"Branched-chain amino acid catabolism"	"Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism"	"3"	"0"	"32.4"	"15.4"	"75.4"	"54.7"	"58.5"	"33.4"	"50.0"	"0.0"	"206.2"	"147.0"	"437.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q494U1"	"Pleckstrin homology domain-containing family N member 1 OS=Homo sapiens OX=9606 GN=PLEKHN1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"611"	"66.4"	"8.79"	""	"2.03"	""	"1"	"stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"other molecular function"	""	"84069"	"ENSG00000187583"	"PLEKHN1"	"hsa:84069; Q494U1; Q494U2; Q5SV98; Q9H0M7"	""	"1p36 copy number variation syndrome"	"1"	"0"	"46.6"	"18.8"	"88.4"	"56.3"	"61.2"	"49.5"	"72.7"	"0.0"	"425.2"	"326.5"	"1349.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86UQ4"	"ATP-binding cassette sub-family A member 13 OS=Homo sapiens OX=9606 GN=ABCA13 PE=2 SV=3"	""	""	"0"	"1"	"2"	"1"	"5058"	"575.8"	"6.46"	""	"2.03"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf12698"	"154664"	"ENSG00000179869"	"ABCA13"	"hsa:154664; K9LC76; K9LC79; K9LCX7; K9LDK8; K9LDY4; Q6ZTT7; Q86UQ4; Q86WI2; Q8N248"	"Neutrophil degranulation"	""	"1"	"0"	"27.3"	"7.9"	"43.6"	"31.4"	"37.5"	"25.6"	"35.2"	"0.0"	"411.5"	"255.0"	"992.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NCM8"	"Cytoplasmic dynein 2 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC2H1 PE=1 SV=4"	""	""	"0"	"1"	"1"	"1"	"4307"	"492.3"	"6.54"	""	"2.03"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf18198, Pf18199"	"79659"	"ENSG00000187240"	"DYNC2H1"	"hsa:79659; O00432; Q16693; Q3C1U8; Q4AC93; Q6ZMX7; Q6ZUM6; Q7Z363; Q8N977; Q8NCM8; Q92815; Q9HAE4"	"Hedgehog 'off' state; Intraflagellar transport"	"Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; 3q29 copy number variation syndrome; Bardet-Biedl syndrome"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q92624"	"Amyloid protein-binding protein 2 OS=Homo sapiens OX=9606 GN=APPBP2 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"585"	"66.8"	"6.90"	""	"2.03"	""	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13374, Pf13424"	"10513"	"ENSG00000062725"	"APPBP2"	"A8K862; hsa:10513; O95095; Q8WVC9; Q92624"	""	""	"0"	"0"	"5.4"	"5.8"	"8.3"	"4.0"	"2.5"	"6.4"	"6.2"	"0.0"	"138.7"	"98.5"	"422.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPR3"	"Protein SMG5 OS=Homo sapiens OX=9606 GN=SMG5 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1016"	"113.9"	"5.91"	""	"2.02"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10373, Pf10374, Pf13638"	"23381"	"ENSG00000198952"	"SMG5"	"D3DVB7; hsa:23381; Q5QJE7; Q659C7; Q8IXC0; Q8IY09; Q96IJ7; Q9UPR3"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"1"	"0"	"15.7"	"6.0"	"23.0"	"21.0"	"15.5"	"15.0"	"34.3"	"0.0"	"600.0"	"617.2"	"1148.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96BH1"	"E3 ubiquitin-protein ligase RNF25 OS=Homo sapiens OX=9606 GN=RNF25 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"459"	"51.2"	"6.54"	""	"2.02"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf05773"	"64320"	"ENSG00000163481"	"RNF25"	"A8K0D6; hsa:64320; Q53HQ5; Q96BH1; Q9H874"	"Antigen processing: Ubiquitination & Proteasome degradation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A4D2H0"	"cTAGE family member 15 OS=Homo sapiens OX=9606 GN=CTAGE15 PE=2 SV=1"	""	""	"2"	"1"	"1"	"1"	"777"	"87.8"	"5.24"	""	"2.02"	""	"1"	"transport"	"other membranes;ER/Golgi"	""	""	"441294"	"ENSG00000271079; ENSG00000285172"	"CTAGE15"	"A4D2H0; A6H8Z8; hsa:441294"	""	""	"0"	"0"	"3.4"	"4.9"	"9.9"	"7.8"	"7.8"	"8.6"	"7.9"	"0.0"	"831.2"	"898.9"	"1514.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95625"	"Zinc finger and BTB domain-containing protein 11 OS=Homo sapiens OX=9606 GN=ZBTB11 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1053"	"119.3"	"8.66"	"520.55"	"2.02"	"2"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf00651, Pf13912, Pf17921"	"27107"	"ENSG00000066422"	"ZBTB11"	"hsa:27107; O95625; Q2NKP9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96BW9"	"Phosphatidate cytidylyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TAMM41 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"452"	"51.0"	"7.94"	""	"2.02"	""	"1"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf09139"	"132001"	"ENSG00000144559"	"TAMM41"	"B4DIY7; C9J2U4; hsa:132001; Q96BW9"	""	""	"0"	"0"	"2.2"	"0.0"	"0.0"	"0.0"	"3.8"	"2.8"	"3.4"	"0.0"	"42.7"	"45.4"	"88.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A8MQB3"	"Putative uncharacterized protein LINC02693 OS=Homo sapiens OX=9606 GN=LINC02693 PE=5 SV=1"	""	""	"7"	"1"	"1"	"1"	"221"	"24.3"	"9.72"	""	"2.02"	""	"1"	""	""	""	"Pf17699"	""	""	"LINC02693"	"A8MQB3; B2RN29; B5MCL4"	""	""	"0"	"0"	"114.1"	"89.8"	"120.7"	"105.4"	"91.0"	"87.7"	"302.0"	"0.0"	"549.8"	"516.3"	"838.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVD9"	"NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"361"	"40.8"	"5.25"	"272.01"	"2.02"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf04969, Pf14050"	"23386"	"ENSG00000015676"	"NUDCD3"	"hsa:23386; Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4"	""	""	"0"	"0"	"29.4"	"13.4"	"25.3"	"20.6"	"23.6"	"34.2"	"32.3"	"1.8"	"519.7"	"540.0"	"914.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14576"	"Cytoplasmic dynein 1 intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1I1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"645"	"72.9"	"5.12"	""	"2.01"	""	"1"	"transport"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf11540"	"1780"	"ENSG00000158560"	"DYNC1I1"	"B4DME3; F5H050; G5E9K1; hsa:1780; O14576; Q8TBF7; Q9Y2X1"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"Intraflagellar transport proteins binding to dynein"	"13"	"0"	"76.6"	"57.1"	"65.0"	"58.5"	"58.2"	"57.1"	"92.7"	"0.0"	"458.8"	"462.5"	"990.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q68D86"	"Coiled-coil domain-containing protein 102B OS=Homo sapiens OX=9606 GN=CCDC102B PE=1 SV=4"	""	""	"4"	"1"	"1"	"1"	"513"	"60.4"	"5.95"	""	"2.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytoskeleton;other cell component"	"other molecular function"	""	"79839"	"ENSG00000150636"	"CCDC102B"	"A1A4H1; hsa:79839; Q68D86; Q7Z467; Q8NDK7; Q9H5C1"	""	""	"0"	"0"	"0.0"	"2.5"	"0.0"	"0.0"	"0.0"	"0.0"	"5.6"	"1.1"	"127.9"	"158.9"	"242.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BVA0"	"Katanin p80 WD40 repeat-containing subunit B1 OS=Homo sapiens OX=9606 GN=KATNB1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"655"	"72.3"	"7.56"	""	"2.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf13925"	"10300"	"ENSG00000140854"	"KATNB1"	"A6NCG6; hsa:10300; O60620; Q9BVA0"	""	"Genes related to primary cilium development (based on CRISPR)"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NSE4"	"Isoleucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=IARS2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1012"	"113.7"	"7.20"	""	"2.00"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf06827, Pf08264"	"55699"	"ENSG00000067704"	"IARS2"	"B2RPG8; hsa:55699; Q1M2P9; Q6PI85; Q7L439; Q86WU9; Q96D91; Q9H9Q8; Q9NSE4; Q9NW42"	"Mitochondrial tRNA aminoacylation"	""	"1"	"0"	"0.0"	"2.7"	"3.5"	"1.7"	"2.7"	"0.0"	"2.8"	"0.0"	"40.6"	"40.7"	"77.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBW7"	"Zinc finger MYM-type protein 2 OS=Homo sapiens OX=9606 GN=ZMYM2 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1377"	"154.8"	"6.34"	"447.62"	"0.00"	"2"	"1"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf06467, Pf12012"	"7750"	"ENSG00000121741"	"ZMYM2"	"A6NDG0; A6NI02; hsa:7750; O43212; O43434; O60898; Q5W0Q4; Q5W0T3; Q63HP0; Q8NE39; Q9H0V5; Q9H538; Q9UBW7; Q9UEU2"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	""	"3"	"0"	"8.1"	"8.9"	"5.8"	"7.6"	"11.5"	"7.8"	"11.3"	"0.0"	"45.6"	"46.7"	"65.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRN7"	"L-aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase OS=Homo sapiens OX=9606 GN=AASDHPPT PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"309"	"35.8"	"6.80"	"267.84"	"0.00"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf01648"	"60496"	"ENSG00000149313"	"AASDHPPT"	"B2R6D1; B4DDW7; hsa:60496; Q9C068; Q9NRN7; Q9P0Q3; Q9UG80; Q9Y389"	"Vitamin B5 (pantothenate) metabolism"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z7A1"	"Centriolin OS=Homo sapiens OX=9606 GN=CNTRL PE=1 SV=2"	"0.000"	""	"1"	"2"	"2"	"1"	"2325"	"268.7"	"5.55"	"251.87"	"0.00"	"1"	"1"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	""	"Pf14580"	"11064"	"ENSG00000119397"	"CNTRL"	"A2A2Y1; B2RP67; hsa:11064; Q3MN79; Q5FWF8; Q5JVD0; Q6MZR3; Q6PKC1; Q7Z7A1; Q8TEP3; Q9Y489"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"15.0"	"12.1"	"8.2"	"11.6"	"11.7"	"16.5"	"34.1"	"0.0"	"185.6"	"204.6"	"354.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NXR4"	"TELO2-interacting protein 2 OS=Homo sapiens OX=9606 GN=TTI2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"508"	"56.9"	"7.09"	"244.41"	"0.00"	"1"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10521"	"80185"	"ENSG00000129696"	"TTI2"	"D3DSV7; hsa:80185; Q6NXR4; Q96IM2; Q9H5N4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H582"	"Zinc finger protein 644 OS=Homo sapiens OX=9606 GN=ZNF644 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1327"	"149.5"	"8.16"	"226.47"	"0.00"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"84146"	"ENSG00000122482"	"ZNF644"	"A2RU71; hsa:84146; Q2TAM0; Q5TCC0; Q6BEP7; Q6P446; Q6PI06; Q7LG67; Q9H582; Q9ULJ9"	""	""	"0"	"0"	"11.1"	"8.4"	"13.5"	"9.1"	"12.0"	"7.9"	"28.6"	"1.7"	"81.7"	"84.7"	"143.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75376"	"Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"2440"	"270.0"	"7.11"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf15784"	"9611"	"ENSG00000141027"	"NCOR1"	"B3DLF8; E9PGV6; hsa:9611; O75376; Q86YY0; Q9UPV5; Q9UQ18"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; HCMV Early Events; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Heme signaling; Transcriptional activation of mitochondrial biogenesis; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Nuclear Receptor transcription pathway; Cytoprotection by HMOX1; Nuclear signaling by ERBB4; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NR1D1 (REV-ERBA) represses gene expression; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Loss of MECP2 binding ability to the NCoR/SMRT complex; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis"	"Androgen receptor signaling pathway; Adipogenesis; Ovarian infertility; MECP2 and associated Rett syndrome; Pathways affected in adenoid cystic carcinoma; Rett syndrome causing genes; 22q11.2 copy number variation syndrome; Notch signaling pathway"	"30"	"0"	"9.3"	"6.4"	"6.7"	"8.1"	"10.0"	"8.7"	"19.1"	"3.4"	"318.1"	"307.5"	"846.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q17RC7"	"Exocyst complex component 3-like protein 4 OS=Homo sapiens OX=9606 GN=EXOC3L4 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"722"	"79.8"	"6.32"	""	"0.00"	""	"1"	"transport;other biological processes"	"other cell component"	"other molecular function"	"Pf06046"	"91828"	"ENSG00000205436"	"EXOC3L4"	"hsa:91828; Q14CR2; Q17RC7"	""	""	"0"	"0"	"12.6"	"6.1"	"7.9"	"8.2"	"9.7"	"7.7"	"16.9"	"0.0"	"177.5"	"172.5"	"499.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NZM4"	"BRD4-interacting chromatin-remodeling complex-associated protein OS=Homo sapiens OX=9606 GN=BICRA PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1560"	"158.4"	"6.65"	""	"0.00"	""	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf15249"	"29998"	"ENSG00000063169"	"BICRA"	"A8MW01; hsa:29998; Q9NZM4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NZ63"	"Telomere length and silencing protein 1 homolog OS=Homo sapiens OX=9606 GN=C9orf78 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"289"	"33.7"	"6.74"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf07052"	"51759"	"ENSG00000136819"	"C9orf78"	"B3KPX8; hsa:51759; Q8WVU6; Q9NT39; Q9NZ63"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"14.9"	"11.1"	"20.5"	"21.4"	"21.1"	"20.6"	"22.7"	"0.0"	"169.8"	"157.7"	"288.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P0DOX2"	"Immunoglobulin alpha-2 heavy chain OS=Homo sapiens OX=9606 PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"455"	"48.9"	"6.67"	""	"0.00"	""	"1"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cell component"	""	"Pf00047, Pf07654, Pf07686"	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BY31"	"Zinc finger protein 717 OS=Homo sapiens OX=9606 GN=ZNF717 PE=2 SV=2"	""	""	"1"	"1"	"1"	"1"	"904"	"105.2"	"8.57"	""	"0.00"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q52LR7"	"Enhancer of polycomb homolog 2 OS=Homo sapiens OX=9606 GN=EPC2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"807"	"91.0"	"8.73"	""	"0.00"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf06752, Pf10513"	"26122"	"ENSG00000135999"	"EPC2"	"B3KWT7; D3DP89; hsa:26122; Q52LR7; Q7L9J1; Q96RR7; Q9NUT8; Q9NVR1; Q9UFM9"	""	""	"0"	"0"	"5.2"	"6.7"	"2.0"	"5.7"	"4.0"	"3.1"	"7.3"	"0.0"	"42.3"	"27.9"	"88.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NQS7"	"Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"918"	"105.4"	"9.44"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03941, Pf12178"	"3619"	"ENSG00000149503"	"INCENP"	"A8MQD2; hsa:3619; Q5Y192; Q9NQS7"	"SUMOylation of DNA replication proteins; RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"7"	"0"	"4.9"	"4.1"	"7.4"	"5.0"	"8.7"	"6.3"	"24.0"	"3.8"	"200.0"	"164.2"	"552.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96S15"	"GATOR complex protein WDR24 OS=Homo sapiens OX=9606 GN=WDR24 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"790"	"88.2"	"6.52"	""	"0.00"	""	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"84219"	"ENSG00000127580"	"WDR24"	"A2IDB8; D3DU59; hsa:84219; Q96GC7; Q96S15; Q9H0B7"	"Amino acids regulate mTORC1"	""	"1"	"0"	"5.2"	"3.4"	"5.5"	"8.3"	"8.7"	"7.6"	"8.8"	"0.2"	"104.5"	"126.1"	"275.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P62253"	"Ubiquitin-conjugating enzyme E2 G1 OS=Homo sapiens OX=9606 GN=UBE2G1 PE=1 SV=3"	""	""	"7"	"1"	"1"	"1"	"170"	"19.5"	"5.30"	""	"0.00"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00179"	"7326"	"ENSG00000132388"	"UBE2G1"	"B2R7P2; D3DTK0; hsa:7326; P62253; Q99462"	"Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IYT3"	"Coiled-coil domain-containing protein 170 OS=Homo sapiens OX=9606 GN=CCDC170 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"715"	"82.2"	"6.64"	""	"0.00"	""	"1"	"cell organization and biogenesis"	"cytoskeleton;ER/Golgi"	"cytoskeletal activity"	""	"80129"	"ENSG00000120262"	"CCDC170"	"hsa:80129; Q5VXB7; Q6P9E4; Q8IYT3; Q96KA9; Q9H5M3"	""	""	"0"	"0"	"20.7"	"9.5"	"51.0"	"26.9"	"33.6"	"22.1"	"49.1"	"0.0"	"521.0"	"403.8"	"1303.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6ZRS2"	"Helicase SRCAP OS=Homo sapiens OX=9606 GN=SRCAP PE=1 SV=3"	""	""	"0"	"1"	"1"	"1"	"3230"	"343.3"	"5.96"	""	"0.00"	""	"1"	"cell organization and biogenesis;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf07529"	"10847"	"ENSG00000080603"	"SRCAP"	"B0JZA6; hsa:10847; O15026; Q6ZRS2; Q7Z744; Q9Y5L9"	""	"Pathways affected in adenoid cystic carcinoma"	"1"	"0"	"16.5"	"13.3"	"22.2"	"16.2"	"20.8"	"20.6"	"40.4"	"0.0"	"819.7"	"805.7"	"1404.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P12109"	"Collagen alpha-1(VI) chain OS=Homo sapiens OX=9606 GN=COL6A1 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"1028"	"108.5"	"5.43"	""	"0.00"	""	"1"	"cell adhesion;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"extracellular structural activity;other molecular function"	"Pf00092, Pf01391"	"1291"	"ENSG00000142156"	"COL6A1"	"hsa:1291; O00117; O00118; P12109; Q14040; Q14041; Q16258; Q7Z645; Q9BSA8"	"Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures; Integrin cell surface interactions; ECM proteoglycans; NCAM1 interactions; Collagen chain trimerization"	"miRNA targets in ECM and membrane receptors; PI3K-Akt signaling pathway"	"10"	"0"	"5.6"	"0.0"	"12.6"	"8.4"	"10.9"	"5.8"	"13.8"	"0.0"	"109.2"	"123.5"	"302.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86XI2"	"Condensin-2 complex subunit G2 OS=Homo sapiens OX=9606 GN=NCAPG2 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1143"	"130.9"	"6.87"	""	"0.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12422"	"54892"	"ENSG00000146918"	"NCAPG2"	"A4D228; hsa:54892; Q7Z3J9; Q86XI2; Q8WUG8; Q9BRX6; Q9H8S2; Q9H9K6"	"Condensation of Prophase Chromosomes"	"Mesodermal commitment pathway"	"2"	"0"	"6.3"	"0.0"	"4.7"	"4.2"	"5.8"	"3.5"	"4.4"	"1.8"	"114.5"	"121.1"	"390.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14647"	"Chromodomain-helicase-DNA-binding protein 2 OS=Homo sapiens OX=9606 GN=CHD2 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1828"	"211.2"	"8.10"	""	"0.00"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf13907, Pf18375"	"1106"	"ENSG00000173575"	"CHD2"	"C6G482; hsa:1106; O14647; Q96IP5"	""	"Prion disease pathway; Male infertility"	"2"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"4.7"	"3.3"	"1.3"	"119.9"	"153.8"	"217.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"B4DJY2"	"Transmembrane protein 233 OS=Homo sapiens OX=9606 GN=TMEM233 PE=3 SV=1"	""	""	"22"	"1"	"1"	"1"	"109"	"12.1"	"5.10"	""	"0.00"	""	"1"	""	"other membranes"	""	"Pf04505"	"387890"	"ENSG00000224982"	"TMEM233"	"B4DJY2; hsa:387890"	""	""	"0"	"0"	"3.1"	"2.8"	"2.4"	"7.3"	"0.0"	"1.4"	"14.8"	"0.0"	"49.8"	"44.2"	"87.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q08174"	"Protocadherin-1 OS=Homo sapiens OX=9606 GN=PCDH1 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1060"	"114.7"	"5.03"	""	"0.00"	""	"1"	"cell adhesion;cell-cell signaling;developmental processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00028, Pf08266, Pf08374"	"5097"	"ENSG00000156453"	"PCDH1"	"hsa:5097; Q08174; Q8IUP2"	""	""	"0"	"0"	"11.2"	"5.6"	"14.6"	"9.7"	"12.4"	"12.9"	"30.5"	"0.0"	"244.5"	"206.9"	"552.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NR96"	"Toll-like receptor 9 OS=Homo sapiens OX=9606 GN=TLR9 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1032"	"115.8"	"8.19"	""	"0.00"	""	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01582, Pf13516, Pf13855, Pf18837"	"54106"	"ENSG00000239732"	"TLR9"	"B3Y661; D1CS56; hsa:54106; Q6UVZ2; Q9HD68; Q9HD69; Q9HD70; Q9NR96; Q9NYC2; Q9NYC3"	"Potential therapeutics for SARS; PI3K Cascade; Trafficking and processing of endosomal TLR; TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"Toll-like receptor signaling related to MyD88; MYD88 distinct input-output pathway; Measles virus infection; Burn wound healing; Genetic causes of porto-sinusoidal vascular disease; Induction of autophagy and toll-like receptor signaling pathways by graphene oxide ; Toll-like receptor signaling pathway"	"14"	"0"	"17.1"	"12.8"	"16.9"	"18.7"	"13.6"	"12.5"	"33.1"	"0.0"	"355.7"	"371.5"	"842.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P24043"	"Laminin subunit alpha-2 OS=Homo sapiens OX=9606 GN=LAMA2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"3122"	"343.7"	"6.40"	""	"0.00"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00052, Pf00053, Pf00054, Pf00055, Pf06008, Pf06009"	"3908"	"ENSG00000196569"	"LAMA2"	"hsa:3908; P24043; Q14736; Q5VUM2; Q93022"	"ECM proteoglycans; Non-integrin membrane-ECM interactions; Laminin interactions; MET activates PTK2 signaling; EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"Arrhythmogenic right ventricular cardiomyopathy; Alpha 6 beta 4 signaling pathway; Focal adhesion; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Acute viral myocarditis; Small cell lung cancer; Pleural mesothelioma; Orexin receptor pathway"	"14"	"0"	"24.0"	"9.8"	"35.5"	"24.7"	"30.4"	"24.1"	"39.0"	"0.0"	"252.3"	"209.0"	"763.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q16560"	"U11/U12 small nuclear ribonucleoprotein 35 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP35 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"246"	"29.4"	"9.86"	""	"0.00"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"11066"	"ENSG00000184209"	"SNRNP35"	"A8K262; hsa:11066; Q16560; Q5XKN9"	"mRNA Splicing - Minor Pathway"	""	"1"	"0"	"131.8"	"36.6"	"182.7"	"130.5"	"141.3"	"124.8"	"191.1"	"0.0"	"365.0"	"229.5"	"809.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P80192"	"Mitogen-activated protein kinase kinase kinase 9 OS=Homo sapiens OX=9606 GN=MAP3K9 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1104"	"121.8"	"5.87"	""	"0.00"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	""	"kinase activity;other molecular function"	"Pf00069, Pf14604"	"4293"	"ENSG00000006432"	"MAP3K9"	"A3KN85; hsa:4293; P80192; Q0D2G7; Q6EH31; Q9H2N5"	""	"Angiopoietin-like protein 8 regulatory pathway; Oxidative damage response; p38 MAPK signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51587"	"Breast cancer type 2 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA2 PE=1 SV=3"	""	""	"1"	"1"	"2"	"1"	"3418"	"384.0"	"6.71"	""	"0.00"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"33.9"	"21.1"	"32.4"	"35.8"	"37.8"	"29.6"	"40.7"	"0.0"	"339.9"	"370.5"	"750.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P021"	"Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"101"	"11.2"	"9.47"	"1122.84"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10235"	"9419"	"ENSG00000119878"	"CRIPT"	"hsa:9419; Q9P021"	""	""	"0"	"0"	"37.1"	"36.7"	"43.8"	"36.7"	"30.7"	"45.7"	"119.5"	"0.0"	"453.7"	"435.6"	"874.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16352"	"Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2"	"0.000"	""	"5"	"2"	"2"	"2"	"499"	"55.4"	"5.40"	"1088.36"	""	"2"	""	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"9118"	"ENSG00000148798"	"INA"	"B1AQK0; hsa:9118; Q16352; Q9BRC5"	""	""	"0"	"0"	"114.5"	"71.9"	"112.7"	"100.7"	"136.9"	"117.2"	"131.9"	"3.2"	"854.1"	"810.5"	"1543.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ84"	"Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"846"	"94.0"	"8.31"	"837.04"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"9156"	"ENSG00000174371"	"EXO1"	"hsa:9156; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0; Q9UQ84"	"Regulation of TP53 Activity through Phosphorylation; Resolution of D-loop Structures through Holliday Junction Intermediates; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"DNA repair pathways, full network; DNA mismatch repair; Primary ovarian insufficiency"	"19"	"0"	"19.4"	"5.7"	"10.7"	"12.3"	"10.5"	"10.9"	"41.9"	"3.8"	"128.3"	"138.3"	"275.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15036"	"Sorting nexin-17 OS=Homo sapiens OX=9606 GN=SNX17 PE=1 SV=1"	"0.000"	""	"6"	"2"	"2"	"2"	"470"	"52.9"	"7.46"	"819.16"	""	"2"	""	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf18116"	"9784"	"ENSG00000115234"	"SNX17"	"B4DQM7; hsa:9784; Q15036; Q53HN7; Q6IAS3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3V6T2"	"Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"1"	"1871"	"215.9"	"6.21"	"747.84"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf19047"	"55704"	"ENSG00000115355"	"CCDC88A"	"A1IGE7; B7ZM78; C9JG83; hsa:55704; Q3V6T2; Q53SF1; Q581G3; Q5HYD0; Q7Z339; Q7Z3C5"	"RND3 GTPase cycle; RND1 GTPase cycle"	"Mesodermal commitment pathway"	"3"	"0"	"33.3"	"21.7"	"30.9"	"32.1"	"23.1"	"25.8"	"43.2"	"0.0"	"673.7"	"759.3"	"1332.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NHQ9"	"ATP-dependent RNA helicase DDX55 OS=Homo sapiens OX=9606 GN=DDX55 PE=1 SV=3"	"0.000"	""	"4"	"2"	"2"	"2"	"600"	"68.5"	"9.25"	"744.49"	""	"2"	""	""	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"57696"	"ENSG00000111364"	"DDX55"	"hsa:57696; Q658L6; Q8IYH0; Q8NHQ9; Q9HCH7"	""	""	"0"	"0"	"0.0"	"0.0"	"8.3"	"0.0"	"0.0"	"0.0"	"9.8"	"1.6"	"79.4"	"78.2"	"214.9"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZL8"	"Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1130"	"119.6"	"4.34"	"733.54"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08166, Pf08167"	"27043"	"ENSG00000141456"	"PELP1"	"hsa:27043; O15450; Q5EGN3; Q6NTE6; Q8IZL8; Q96FT1; Q9BU60"	"Major pathway of rRNA processing in the nucleolus and cytosol; PTK6 Expression"	""	"2"	"0"	"15.6"	"6.1"	"14.5"	"9.4"	"7.0"	"2.5"	"34.0"	"1.4"	"141.6"	"144.5"	"269.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46100"	"Transcriptional regulator ATRX OS=Homo sapiens OX=9606 GN=ATRX PE=1 SV=5"	"0.000"	""	"1"	"1"	"1"	"1"	"2492"	"282.4"	"6.58"	"683.00"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"40.1"	"26.5"	"49.3"	"45.9"	"27.2"	"40.1"	"52.7"	"2.8"	"409.0"	"377.4"	"850.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UN37"	"Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"437"	"48.9"	"7.80"	"640.96"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"27183"	"ENSG00000132612"	"VPS4A"	"B2RCB7; hsa:27183; Q8TF07; Q9UI03; Q9UN37; Q9Y582"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III"	"Ebola virus infection in host; Ciliary landscape"	"6"	"0"	"3.7"	"3.1"	"2.8"	"3.3"	"2.5"	"3.2"	"6.8"	"2.9"	"75.3"	"77.4"	"139.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02768"	"Serum albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"609"	"69.3"	"6.28"	"640.88"	""	"1"	""	"stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00273"	"213"	"ENSG00000163631"	"ALB"	"E7ESS9; hsa:213; O95574; P02768; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0"	"Scavenging of heme from plasma; Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Cytoprotection by HMOX1; Aspirin ADME; Ciprofloxacin ADME; Recycling of bile acids and salts; Prednisone ADME; Heme degradation; HDL remodeling; Heme biosynthesis"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Complement system; VEGFA-VEGFR2 signaling"	"17"	"0"	"9.4"	"7.5"	"9.1"	"8.8"	"6.2"	"10.0"	"29.0"	"0.5"	"73.0"	"68.8"	"130.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6R0"	"ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"707"	"78.8"	"8.91"	"628.16"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"56919"	"ENSG00000005100"	"DHX33"	"B4DHF9; hsa:56919; Q4G149; Q5CZ73; Q9H5M9; Q9H6R0"	""	""	"0"	"0"	"22.7"	"20.0"	"19.4"	"19.1"	"14.6"	"21.2"	"59.3"	"0.0"	"116.4"	"131.5"	"171.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82912"	"28S ribosomal protein S11, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS11 PE=1 SV=2"	"0.000"	""	"9"	"1"	"1"	"1"	"194"	"20.6"	"10.81"	"615.91"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"64963"	"ENSG00000181991"	"MRPS11"	"B2RD52; hsa:64963; P82912; Q969D7; Q96GI3; Q9BYC3"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	""	"3"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"3.8"	"4.1"	"2.9"	"0.0"	"43.3"	"40.1"	"106.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WX3"	"Active regulator of SIRT1 OS=Homo sapiens OX=9606 GN=RPS19BP1 PE=1 SV=1"	"0.000"	""	"10"	"1"	"1"	"1"	"136"	"15.4"	"10.74"	"613.34"	""	"1"	""	"other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf15684"	"91582"	"ENSG00000187051"	"RPS19BP1"	"B0QY96; hsa:91582; Q5JZA1; Q86WX3"	"Regulation of HSF1-mediated heat shock response"	""	"1"	"0"	"22.1"	"18.2"	"19.6"	"17.8"	"18.0"	"19.2"	"45.7"	"0.0"	"173.0"	"163.7"	"347.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63000"	"Ras-related C3 botulinum toxin substrate 1 OS=Homo sapiens OX=9606 GN=RAC1 PE=1 SV=1"	"0.000"	""	"8"	"1"	"1"	"1"	"192"	"21.4"	"8.50"	"586.26"	""	"1"	""	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5879"	"ENSG00000136238"	"RAC1"	"hsa:5879; O95501; P15154; P63000; Q3Y4D3; Q5JAA8; Q9BTB4"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling; RAC1 GTPase cycle; NRAGE signals death through JNK; DCC mediated attractive signaling; Neutrophil degranulation; PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; FCERI mediated MAPK activation; MAPK6/MAPK4 signaling; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; GPVI-mediated activation cascade; Signaling by SCF-KIT; DAP12 signaling; Ephrin signaling; Factors involved in megakaryocyte development and platelet production; RHO GTPases activate CIT; PCP/CE pathway; WNT5:FZD7-mediated leishmania damping; EPH-ephrin mediated repulsion of cells; Sema3A PAK dependent Axon repulsion; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Signal transduction by L1; RHO GTPases activate PKNs; RHO GTPases activate PAKs; DSCAM interactions; Azathioprine ADME; VEGFR2 mediated vascular permeability; Sema4D mediated inhibition of cell attachment and migration; Inactivation of CDC42 and RAC1; Activation of RAC1; CD28 dependent Vav1 pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Nef and signal transduction; RHO GTPases Activate NADPH Oxidases; NTRK2 activates RAC1; MET activates RAP1 and RAC1; Activation of RAC1 downstream of NMDARs; Activated NTRK2 signals through CDK5; RHO GTPases activate KTN1"	"Androgen receptor signaling pathway; Nucleotide-binding oligomerization domain (NOD) pathway; Target of rapamycin signaling; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; RalA downstream regulated genes; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Amyotrophic lateral sclerosis (ALS); Cardiac hypertrophic response; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; Robo4 and VEGF signaling pathways crosstalk; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Ciliary landscape; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Gastrin signaling pathway; Melanoma; Netrin-UNC5B signaling pathway; Insulin signaling; CAMKK2 pathway; Opioid receptor pathways; Regulation of actin cytoskeleton; GDNF signaling; 2q13 copy number variation syndrome; 2q21.1 copy number variation syndrome; 2q37 copy number variation syndrome; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; TROP2 regulatory signaling; 13q12.12 copy number variation; Interferon type I signaling pathways; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"108"	"0"	"16.1"	"19.7"	"20.4"	"14.1"	"17.1"	"18.3"	"69.2"	"0.0"	"575.0"	"602.0"	"1160.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBB5"	"Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"411"	"43.2"	"10.04"	"560.61"	""	"1"	""	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"8932"	"ENSG00000134046"	"MBD2"	"hsa:8932; O95242; Q9UBB5; Q9UIS8"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Opening"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"3"	"0"	"6.1"	"2.3"	"5.9"	"3.6"	"10.3"	"5.1"	"13.9"	"0.9"	"56.9"	"63.6"	"124.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y365"	"START domain-containing protein 10 OS=Homo sapiens OX=9606 GN=STARD10 PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"291"	"33.0"	"7.12"	"554.56"	""	"1"	""	"transport"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01852"	"10809"	"ENSG00000214530"	"STARD10"	"hsa:10809; O60532; Q9Y365"	"Synthesis of PC"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"203.8"	"206.3"	"525.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GX5"	"Serine/threonine-protein kinase greatwall OS=Homo sapiens OX=9606 GN=MASTL PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"879"	"97.3"	"5.99"	"550.65"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"84930"	"ENSG00000120539"	"MASTL"	"hsa:84930; Q5T8D5; Q5T8D7; Q8NCD6; Q96GX5; Q96SJ5"	"MASTL Facilitates Mitotic Progression"	""	"1"	"0"	"5.6"	"3.3"	"3.2"	"6.1"	"3.5"	"4.0"	"5.2"	"0.0"	"34.6"	"34.5"	"67.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56181"	"NADH dehydrogenase [ubiquinone] flavoprotein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV3 PE=1 SV=2"	"0.000"	""	"15"	"1"	"1"	"1"	"108"	"11.9"	"9.70"	"535.34"	""	"1"	""	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf15880"	"4731"	"ENSG00000160194"	"NDUFV3"	"A8K0M1; hsa:4731; J3KNX7; P56181; Q6FGD3; Q8WU60; Q9HCR5"	"Complex I biogenesis"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"5"	"0"	"27.6"	"24.3"	"20.3"	"19.2"	"22.5"	"25.7"	"44.1"	"0.0"	"245.2"	"245.6"	"377.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43633"	"Charged multivesicular body protein 2a OS=Homo sapiens OX=9606 GN=CHMP2A PE=1 SV=1"	"0.000"	""	"9"	"1"	"1"	"1"	"222"	"25.1"	"5.97"	"529.77"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"27243"	"ENSG00000130724"	"CHMP2A"	"B2R4W6; hsa:27243; O43633; Q3ZTT0"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Late endosomal microautophagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Lysosome Vesicle Biogenesis; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	""	"10"	"0"	"9.2"	"7.2"	"12.0"	"10.9"	"8.7"	"12.2"	"20.8"	"0.0"	"148.6"	"181.9"	"315.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXD5"	"Gem-associated protein 6 OS=Homo sapiens OX=9606 GN=GEMIN6 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"167"	"18.8"	"5.12"	"527.87"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf06372, Pf20417"	"79833"	"ENSG00000152147"	"GEMIN6"	"B2RDP8; hsa:79833; Q53SI5; Q8WVB4; Q8WXD5; Q9H5G6"	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	""	"2"	"0"	"25.6"	"34.9"	"24.4"	"32.1"	"23.0"	"25.0"	"61.4"	"0.0"	"320.0"	"312.4"	"669.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAF1"	"Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"191"	"21.6"	"9.32"	"523.89"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf09340"	"64769"	"ENSG00000163875"	"MEAF6"	"B1AK64; hsa:64769; Q4F967; Q7Z311; Q86WE3; Q9HAF1"	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	""	"2"	"0"	"14.7"	"8.9"	"8.5"	"1.7"	"2.8"	"10.4"	"49.0"	"0.0"	"116.2"	"109.1"	"191.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94905"	"Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"339"	"37.8"	"5.62"	"519.79"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01145"	"11160"	"ENSG00000147475"	"ERLIN2"	"A0JLQ1; A8K5S9; B4DM38; D3DSW0; hsa:11160; O94905; Q6NW21; Q86VS6; Q86W49"	"ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions"	""	"4"	"0"	"36.7"	"23.1"	"47.3"	"33.5"	"30.9"	"49.7"	"66.8"	"0.0"	"435.9"	"439.1"	"778.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27824"	"Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"592"	"67.5"	"4.60"	"514.52"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00262"	"821"	"ENSG00000127022; ENSG00000283777"	"CANX"	"B2R5V8; B4DGP8; B4E2T8; D3DWQ3; D6R9K3; hsa:821; P27824"	"Maturation of spike protein; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Interleukin-35 Signalling; Interleukin-27 signaling; Assembly of Viral Components at the Budding Site; Calnexin/calreticulin cycle; Maturation of spike protein"	"15q11q13 copy number variation"	"9"	"0"	"16.7"	"11.6"	"23.0"	"14.0"	"14.0"	"19.2"	"37.6"	"0.0"	"244.4"	"250.4"	"723.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH92"	"Max-like protein X OS=Homo sapiens OX=9606 GN=MLX PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"298"	"33.3"	"8.06"	"504.67"	""	"1"	""	"other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"6945"	"ENSG00000108788"	"MLX"	"A8K2J3; B2RAV8; B2RD73; hsa:6945; Q53XM6; Q96FL2; Q9H2V0; Q9H2V1; Q9H2V2; Q9NXN3; Q9UH92"	"ChREBP activates metabolic gene expression"	"Nonalcoholic fatty liver disease"	"2"	"0"	"57.2"	"65.7"	"19.5"	"121.6"	"56.9"	"55.1"	"158.7"	"0.0"	"444.0"	"2043.1"	"285.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53EZ4"	"Centrosomal protein of 55 kDa OS=Homo sapiens OX=9606 GN=CEP55 PE=1 SV=3"	"0.000"	""	"3"	"1"	"1"	"1"	"464"	"54.1"	"7.01"	"501.47"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"other molecular function"	"Pf12180"	"55165"	"ENSG00000138180"	"CEP55"	"B2RDG8; D3DR37; hsa:55165; Q32WF5; Q3MV20; Q53EZ4; Q5VY28; Q6N034; Q96H32; Q9NVS7"	""	""	"0"	"0"	"85.0"	"57.2"	"68.5"	"65.0"	"64.1"	"87.0"	"117.6"	"0.4"	"414.2"	"346.2"	"679.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15631"	"Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"228"	"26.2"	"6.44"	"499.19"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01997"	"7247"	"ENSG00000211460"	"TSN"	"B7Z3X8; hsa:7247; Q15631; Q5U0K7"	"Small interfering RNA (siRNA) biogenesis"	""	"1"	"0"	"19.7"	"18.1"	"25.0"	"18.6"	"19.3"	"14.3"	"29.4"	"0.0"	"216.1"	"251.7"	"508.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6X9"	"ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1032"	"117.8"	"8.38"	"497.85"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf07496, Pf13589, Pf17942"	"22880"	"ENSG00000133422"	"MORC2"	"B2RNB1; hsa:22880; Q9UF28; Q9Y6V2; Q9Y6X9"	"Fatty acyl-CoA biosynthesis"	""	"1"	"0"	"8.9"	"10.0"	"15.0"	"13.4"	"12.1"	"4.5"	"42.7"	"0.0"	"354.4"	"373.4"	"992.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99698"	"Lysosomal-trafficking regulator OS=Homo sapiens OX=9606 GN=LYST PE=1 SV=3"	"0.000"	""	"0"	"2"	"2"	"2"	"3801"	"428.9"	"6.61"	"497.44"	""	"2"	""	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf00400, Pf02138, Pf14844"	"1130"	"ENSG00000143669"	"LYST"	"hsa:1130; O43274; Q5T2U9; Q96TD7; Q96TD8; Q99698; Q99709; Q9H133"	""	""	"0"	"0"	"149.8"	"110.2"	"127.6"	"128.5"	"148.4"	"134.3"	"228.9"	"0.0"	"1132.2"	"1126.1"	"2098.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6I4"	"Ubiquitin carboxyl-terminal hydrolase 3 OS=Homo sapiens OX=9606 GN=USP3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"520"	"58.9"	"8.18"	"494.09"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00443, Pf02148"	"9960"	"ENSG00000140455"	"USP3"	"B4DVU5; F5H1A6; hsa:9960; Q8WVD0; Q9Y6I4"	"Ub-specific processing proteases"	""	"1"	"0"	"4.5"	"5.1"	"7.6"	"6.7"	"5.6"	"6.1"	"19.5"	"1.5"	"83.5"	"92.1"	"131.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PJT7"	"Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"736"	"82.8"	"7.31"	"490.49"	""	"1"	""	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14608"	"79882"	"ENSG00000100722"	"ZC3H14"	"A8MY46; B4DXU8; B4DZW7; B4E2H4; G3V5R4; hsa:79882; Q6MZU4; Q6PJ32; Q6PJT7; Q6PUI6; Q6PUI8; Q86TQ5; Q86TW0; Q86TW1; Q8NCT6; Q8NCZ3; Q8TDE2; Q9HAC9; Q9Y5A0"	""	""	"0"	"0"	"20.8"	"17.9"	"17.8"	"16.4"	"17.8"	"26.3"	"50.2"	"0.0"	"122.6"	"125.3"	"216.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDX7"	"Serine/threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"302"	"34.5"	"8.25"	"482.67"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"140609"	"ENSG00000151414"	"NEK7"	"A6NGT8; hsa:140609; Q8TDX7"	"EML4 and NUDC in mitotic spindle formation; Nuclear Pore Complex (NPC) Disassembly; Activation of NIMA Kinases NEK9, NEK6, NEK7"	"Ciliary landscape"	"4"	"0"	"9.7"	"6.6"	"14.6"	"9.0"	"11.3"	"10.0"	"16.1"	"0.0"	"285.8"	"298.3"	"677.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92615"	"La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"738"	"80.5"	"6.92"	"482.18"	""	"1"	""	"other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05383"	"23185"	"ENSG00000107929"	"LARP4B"	"A7MD20; hsa:23185; Q5T3R3; Q5T3R4; Q5T3R5; Q68CY4; Q92615"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15460"	"Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"535"	"60.9"	"5.71"	"481.95"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"8974"	"ENSG00000072682"	"P4HA2"	"D3DQ85; D3DQ86; hsa:8974; O15460; Q8WWN0"	"Collagen biosynthesis and modifying enzymes"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Type I collagen synthesis in the context of osteogenesis imperfecta"	"4"	"0"	"9.0"	"8.8"	"2.9"	"5.9"	"7.6"	"7.0"	"6.8"	"0.0"	"32.3"	"33.4"	"68.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PIJ6"	"F-box only protein 38 OS=Homo sapiens OX=9606 GN=FBXO38 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1188"	"133.9"	"6.33"	"462.22"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00646"	"81545"	"ENSG00000145868"	"FBXO38"	"hsa:81545; Q6PIJ6; Q6PK72; Q7Z2U0; Q86VN3; Q9BXY6; Q9H837; Q9HC40"	""	""	"0"	"0"	"7.0"	"4.6"	"0.0"	"0.0"	"6.2"	"0.0"	"6.2"	"0.0"	"50.1"	"48.9"	"165.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKK9"	"ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"219"	"24.3"	"4.94"	"460.86"	""	"1"	""	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11164"	"ENSG00000165609"	"NUDT5"	"A8K516; hsa:11164; Q6IAG0; Q9UH49; Q9UKK9"	"Phosphate bond hydrolysis by NUDT proteins"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15228"	"Dihydroxyacetone phosphate acyltransferase OS=Homo sapiens OX=9606 GN=GNPAT PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"680"	"77.1"	"6.57"	"459.70"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf01553, Pf19277"	"8443"	"ENSG00000116906"	"GNPAT"	"B4DNM9; hsa:8443; O15228; Q5TBH7; Q9BWC2"	"Peroxisomal protein import; Plasmalogen biosynthesis; Synthesis of PA"	"Triacylglyceride synthesis"	"4"	"0"	"5.4"	"7.9"	"13.8"	"7.8"	"11.1"	"7.4"	"16.4"	"1.4"	"112.8"	"120.1"	"231.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04183"	"Thymidine kinase, cytosolic OS=Homo sapiens OX=9606 GN=TK1 PE=1 SV=2"	"0.000"	""	"8"	"1"	"1"	"1"	"234"	"25.5"	"8.51"	"448.53"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf00265"	"7083"	"ENSG00000167900"	"TK1"	"B2RC58; hsa:7083; P04183; Q969V0; Q9UMG9"	"Pyrimidine salvage; G1/S-Specific Transcription"	"Fluoropyrimidine activity; Pyrimidine metabolism"	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"1.5"	"0.0"	"23.5"	"29.2"	"63.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H668"	"CST complex subunit STN1 OS=Homo sapiens OX=9606 GN=STN1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"368"	"42.1"	"6.07"	"443.30"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01336, Pf09170"	"79991"	"ENSG00000107960"	"STN1"	"D3DR99; hsa:79991; Q5TCZ0; Q9H668"	"Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation"	"Lung fibrosis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13572"	"Inositol-tetrakisphosphate 1-kinase OS=Homo sapiens OX=9606 GN=ITPK1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"414"	"45.6"	"6.16"	"422.80"	""	"1"	""	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf05770, Pf17927"	"3705"	"ENSG00000100605; ENSG00000274958"	"ITPK1"	"hsa:3705; Q13572; Q9BTL6; Q9H2E7"	"Factors involved in megakaryocyte development and platelet production; Synthesis of IP3 and IP4 in the cytosol; Synthesis of pyrophosphates in the cytosol"	"2q37 copy number variation syndrome"	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"30.6"	"30.7"	"107.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22694"	"cAMP-dependent protein kinase catalytic subunit beta OS=Homo sapiens OX=9606 GN=PRKACB PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"351"	"40.6"	"8.78"	"419.62"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"5567"	"ENSG00000142875"	"PRKACB"	"B1APG4; B4DKB0; B4E2Q1; hsa:5567; P22694; Q14VH1; Q59GC0; Q5BNE9; Q5BNF0; Q5BNF1; Q5BNF2; Q5BNF3; Q5CZ92; Q5T1K3; Q7Z3M1; Q8IYR5; Q8IZQ0; Q96B09"	"CD209 (DC-SIGN) signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; FCGR3A-mediated IL10 synthesis; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; MAPK6/MAPK4 signaling; Triglyceride catabolism; RET signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Rap1 signalling; HDL assembly; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5; PKA-mediated phosphorylation of key metabolic factors"	"AMP-activated protein kinase signaling; Dopamine metabolism; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; MAPK signaling pathway; Cannabinoid receptor signaling; Chemokine signaling pathway; Lipid metabolism pathway; Ras signaling; Hedgehog signaling pathway; Thermogenesis; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GPR143 in melanocytes and retinal pigment epithelium cells; Cardiomyocyte signaling pathways converging on Titin; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"44"	"0"	"23.8"	"19.4"	"28.7"	"20.5"	"26.1"	"19.4"	"38.6"	"0.0"	"166.9"	"171.3"	"447.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB46"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C OS=Homo sapiens OX=9606 GN=ANKRD52 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"1076"	"115.0"	"6.48"	"414.03"	""	"1"	""	""	""	""	"Pf00023, Pf12796"	"283373"	"ENSG00000139645"	"ANKRD52"	"A6NE79; B1Q2K2; hsa:283373; Q8NB46"	""	""	"0"	"0"	"3.1"	"0.0"	"2.4"	"3.7"	"1.6"	"2.1"	"4.8"	"0.0"	"32.3"	"33.4"	"54.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRR8"	"G patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GPATCH1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"931"	"103.3"	"7.05"	"411.61"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf07713"	"55094"	"ENSG00000076650"	"GPATCH1"	"hsa:55094; Q8IZV6; Q8N3B7; Q9BRR8; Q9NW94"	"mRNA Splicing - Major Pathway"	""	"1"	"0"	"8.8"	"5.3"	"5.5"	"7.7"	"10.0"	"6.8"	"10.8"	"0.0"	"33.8"	"33.7"	"73.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75152"	"Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"810"	"89.1"	"8.37"	"405.23"	""	"1"	""	"other metabolic processes;transport"	"nucleus"	"other molecular function"	"Pf15663"	"9877"	"ENSG00000058673"	"ZC3H11A"	"hsa:9877; O75152; Q6AHY4; Q6AHY9; Q6AW79; Q6AWA1; Q6PJK4; Q86XZ7"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	""	"3"	"0"	"0.0"	"2.4"	"0.0"	"3.7"	"0.0"	"0.0"	"7.0"	"0.0"	"21.9"	"24.6"	"54.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75044"	"SLIT-ROBO Rho GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=SRGAP2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"1071"	"120.8"	"6.70"	"397.78"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00611, Pf00620"	"23380"	"ENSG00000266028"	"SRGAP2"	"A2RUF3; hsa:23380; O75044"	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate Formins; RAC3 GTPase cycle; RHOF GTPase cycle; RHOU GTPase cycle; Inactivation of CDC42 and RAC1"	""	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15051"	"IQ calmodulin-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=IQCB1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"598"	"68.9"	"9.10"	"389.32"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00612"	"9657"	"ENSG00000173226"	"IQCB1"	"hsa:9657; Q15051; Q3KS08; Q3KS09; Q5DKQ7; Q8NI79; Q9BS08"	"Anchoring of the basal body to the plasma membrane"	"Ciliary landscape; Ciliopathies; Bardet-Biedl syndrome"	"4"	"0"	"4.5"	"4.1"	"6.6"	"4.2"	"7.9"	"7.7"	"7.6"	"2.5"	"62.7"	"64.4"	"132.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U44"	"N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"580"	"64.4"	"6.42"	"387.61"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05063"	"56339"	"ENSG00000165819"	"METTL3"	"hsa:56339; O14736; Q86U44; Q86V05; Q9HB32"	"Processing of Capped Intron-Containing Pre-mRNA"	"mRNA processing"	"2"	"0"	"5.6"	"3.2"	"6.6"	"0.0"	"2.2"	"0.0"	"7.3"	"0.0"	"37.6"	"42.4"	"68.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JJ7"	"Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"454"	"51.8"	"4.91"	"368.89"	""	"1"	""	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"54495"	"ENSG00000166479"	"TMX3"	"B3KV75; hsa:54495; Q52LT7; Q8N5J0; Q96JJ7; Q9NWJ9"	"Platelet degranulation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8K8P3"	"Protein SFI1 homolog OS=Homo sapiens OX=9606 GN=SFI1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1242"	"147.6"	"10.81"	"362.80"	""	"1"	""	""	"cytosol;cytoskeleton"	"other molecular function"	""	"9814"	"ENSG00000198089"	"SFI1"	"A1L373; A1L387; A2A2L2; A8K8P3; B1AKL9; B5MDB7; B7Z1V6; B7Z8G3; B7ZBE2; B7ZBE3; hsa:9814; O60289; Q2TAN8; Q5W1B5; Q86TK0; Q8N4U8; Q8N8C1; Q8WU14"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"3.2"	"0.0"	"0.0"	"2.3"	"2.2"	"2.3"	"17.7"	"1.6"	"164.8"	"144.7"	"205.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H1J1"	"Regulator of nonsense transcripts 3A OS=Homo sapiens OX=9606 GN=UPF3A PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"476"	"54.7"	"9.03"	"353.68"	""	"1"	""	"transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03467"	"65110"	"ENSG00000169062"	"UPF3A"	"A2A366; hsa:65110; Q5T8C3; Q5T8C9; Q7Z6N3; Q86YK1; Q9BZI8; Q9H1J1"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52926"	"High mobility group protein HMGI-C OS=Homo sapiens OX=9606 GN=HMGA2 PE=1 SV=1"	"0.000"	""	"17"	"1"	"1"	"1"	"109"	"11.8"	"10.62"	"350.10"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02178"	"8091"	"ENSG00000149948"	"HMGA2"	"E7EP85; E7EWA2; hsa:8091; P52926; Q1M182; Q1M185; Q1M186; Q1M187; Q1M188"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Orexin receptor pathway"	"6"	"0"	"4.2"	"5.5"	"4.2"	"8.4"	"3.2"	"6.4"	"18.2"	"0.0"	"43.8"	"50.8"	"103.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14646"	"Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1710"	"196.6"	"7.14"	"344.27"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf13907, Pf18375"	"1105"	"ENSG00000153922"	"CHD1"	"hsa:1105; O14646; Q17RZ3"	"Estrogen-dependent gene expression"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"7.7"	"0.9"	"35.7"	"40.4"	"101.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULX3"	"RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"412"	"46.6"	"7.18"	"343.76"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08772, Pf15017, Pf17146"	"28987"	"ENSG00000141101"	"NOB1"	"hsa:28987; Q7L6B7; Q7M4M4; Q7Z4B5; Q9NWB0; Q9ULX3"	"Major pathway of rRNA processing in the nucleolus and cytosol"	""	"1"	"0"	"0.0"	"0.0"	"2.0"	"0.0"	"0.0"	"0.0"	"5.3"	"0.0"	"37.6"	"30.5"	"54.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IPR3"	"tRNA wybutosine-synthesizing protein 3 homolog OS=Homo sapiens OX=9606 GN=TYW3 PE=1 SV=2"	"0.000"	""	"7"	"1"	"1"	"1"	"259"	"29.8"	"7.68"	"335.36"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"other molecular function"	"Pf02676"	"127253"	"ENSG00000162623"	"TYW3"	"B4DSP9; E9PGR7; hsa:127253; Q5HYJ0; Q6IPR3; Q8N7L1"	"Synthesis of wybutosine at G37 of tRNA(Phe)"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"4.9"	"0.0"	"32.7"	"37.3"	"72.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WA6"	"Valacyclovir hydrolase OS=Homo sapiens OX=9606 GN=BPHL PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"291"	"32.5"	"9.14"	"334.08"	""	"1"	""	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00561"	"670"	"ENSG00000137274"	"BPHL"	"hsa:670; Q00306; Q13855; Q3KP51; Q86WA6"	"Phase I - Functionalization of compounds"	""	"1"	"0"	"0.0"	"0.0"	"3.1"	"2.1"	"0.0"	"3.0"	"6.1"	"0.0"	"40.5"	"50.3"	"112.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12860"	"Contactin-1 OS=Homo sapiens OX=9606 GN=CNTN1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"1018"	"113.2"	"5.90"	"330.81"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00041, Pf07679, Pf13927"	"1272"	"ENSG00000018236"	"CNTN1"	"A8K0H9; A8K0Y3; hsa:1272; Q12860; Q12861; Q14030; Q7M4P0; Q8N466"	"Activated NOTCH1 Transmits Signal to the Nucleus; NOTCH2 Activation and Transmission of Signal to the Nucleus; Neurofascin interactions"	""	"4"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.1"	"0.0"	"35.5"	"39.5"	"134.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14192"	"Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3"	"0.000"	""	"4"	"1"	"1"	"1"	"279"	"32.2"	"7.55"	"321.03"	""	"1"	""	"developmental processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00412"	"2274"	"ENSG00000115641"	"FHL2"	"hsa:2274; Q13229; Q13644; Q14192; Q2I5I4; Q5TM15; Q9P294"	"PPARA activates gene expression"	"Androgen receptor signaling pathway; RANKL/RANK signaling pathway; Ectoderm differentiation; VEGFA-VEGFR2 signaling"	"5"	"0"	"11.6"	"9.3"	"5.3"	"7.5"	"6.3"	"5.1"	"18.8"	"3.0"	"68.2"	"77.9"	"99.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR33"	"DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2"	"0.000"	""	"9"	"1"	"1"	"1"	"117"	"12.2"	"4.92"	"316.77"	""	"1"	""	"DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"56655"	"ENSG00000115350"	"POLE4"	"hsa:56655; Q53TR2; Q9NR33"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"Pyrimidine metabolism; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"16"	"0"	"0.0"	"0.0"	"2.1"	"0.0"	"2.6"	"0.0"	"4.0"	"0.0"	"36.4"	"31.6"	"58.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60763"	"Ras-related C3 botulinum toxin substrate 3 OS=Homo sapiens OX=9606 GN=RAC3 PE=1 SV=1"	"0.000"	""	"8"	"1"	"1"	"1"	"192"	"21.4"	"8.15"	"316.56"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00071"	"5881"	"ENSG00000169750"	"RAC3"	"hsa:5881; O14658; P60763; Q5U0M8"	"RAC3 GTPase cycle; PCP/CE pathway"	"Integrin-mediated cell adhesion; RalA downstream regulated genes; Focal adhesion; MAPK signaling pathway; Microglia pathogen phagocytosis pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Regulation of actin cytoskeleton"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"B7ZAP0"	"Rab GTPase-activating protein 1-like, isoform 10 OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"253"	"29.0"	"5.33"	"310.43"	""	"1"	""	""	""	""	""	"9910"	"ENSG00000152061"	"RABGAP1L"	"B7ZAA4; B7ZAP0; hsa:9910"	""	""	"0"	"0"	"71.9"	"47.4"	"63.1"	"51.4"	"61.0"	"54.2"	"102.4"	"1.2"	"712.4"	"658.5"	"1026.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14908"	"PDZ domain-containing protein GIPC1 OS=Homo sapiens OX=9606 GN=GIPC1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"333"	"36.0"	"6.28"	"309.66"	""	"1"	""	"cell-cell signaling;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00595"	"10755"	"ENSG00000123159"	"GIPC1"	"A8K4I3; A8MZG3; hsa:10755; O14908; Q9BTC9"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	"3.0"	"2.7"	"4.9"	"3.6"	"4.9"	"7.2"	"7.6"	"1.6"	"86.7"	"82.0"	"173.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Z7"	"Host cell factor 2 OS=Homo sapiens OX=9606 GN=HCFC2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"792"	"86.7"	"8.48"	"302.67"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf13415"	"29915"	"ENSG00000111727"	"HCFC2"	"B2R8Q5; C0H5X3; hsa:29915; Q9Y5Z7"	"Formation of WDR5-containing histone-modifying complexes"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HBM1"	"Kinetochore protein Spc25 OS=Homo sapiens OX=9606 GN=SPC25 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"224"	"26.1"	"8.00"	"302.30"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08234"	"57405"	"ENSG00000152253; ENSG00000277909"	"SPC25"	"A8K4X8; D3DPC0; hsa:57405; Q9HBM1"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	""	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94927"	"HAUS augmin-like complex subunit 5 OS=Homo sapiens OX=9606 GN=HAUS5 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"633"	"71.6"	"8.51"	"290.55"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	"Pf14817"	"23354"	"ENSG00000249115"	"HAUS5"	"B2RXK1; hsa:23354; O94927; Q6P2P7; Q7L3D5; Q96CT8"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	""	"7"	"0"	"8.8"	"8.4"	"10.3"	"10.5"	"9.4"	"6.5"	"16.9"	"2.0"	"91.8"	"96.0"	"170.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A1L0T0"	"2-hydroxyacyl-CoA lyase 2 OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"632"	"67.8"	"8.15"	"290.54"	""	"1"	""	"other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"10994"	"ENSG00000105135"	"ILVBL"	"A1L0T0; hsa:10994; O43341; Q96F08; Q99651; Q9BWN5; Q9UEB2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZXV5"	"Protein O-mannosyl-transferase TMTC3 OS=Homo sapiens OX=9606 GN=TMTC3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"915"	"103.9"	"8.87"	"290.00"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf08409, Pf13174, Pf13181, Pf13431"	"160418"	"ENSG00000139324"	"TMTC3"	"hsa:160418; Q5CZ86; Q5H9T6; Q68DQ6; Q68DX0; Q6ZXV5; Q7Z332; Q8NC50"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23508"	"Colorectal mutant cancer protein OS=Homo sapiens OX=9606 GN=MCC PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"829"	"93.0"	"5.52"	"289.00"	""	"1"	""	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf10506"	"4163"	"ENSG00000171444"	"MCC"	"D3DT05; hsa:4163; P23508; Q6ZR04"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6Y7W6"	"GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"1299"	"150.0"	"5.54"	"283.61"	""	"1"	""	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02213"	"26058"	"ENSG00000204120"	"GIGYF2"	"A6H8W4; B9EG55; E9PBB0; hsa:26058; O75137; Q6Y7W6; Q7Z2Z8; Q7Z3I2; Q96HU4; Q9NV82"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR48"	"Histone-lysine N-methyltransferase ASH1L OS=Homo sapiens OX=9606 GN=ASH1L PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"2969"	"332.6"	"9.39"	"283.50"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00856, Pf01426, Pf17907"	"55870"	"ENSG00000116539"	"ASH1L"	"hsa:55870; Q59GP1; Q5T714; Q5T715; Q9NR48; Q9P2C7"	"PKMTs methylate histone lysines"	"Histone modifications"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4X1"	"Regulator of cell cycle RGCC OS=Homo sapiens OX=9606 GN=RGCC PE=1 SV=1"	"0.000"	""	"8"	"1"	"1"	"1"	"137"	"14.6"	"4.75"	"279.26"	""	"1"	""	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf15151"	"28984"	"ENSG00000102760"	"RGCC"	"hsa:28984; Q6NZ48; Q9H4X1; Q9UL69"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0ZGT2"	"Nexilin OS=Homo sapiens OX=9606 GN=NEXN PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"675"	"80.6"	"5.33"	"273.36"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"91624"	"ENSG00000162614"	"NEXN"	"A0PJ84; B4DPZ7; hsa:91624; Q0D2H2; Q0ZGT2; Q14CC2; Q14CC3; Q16081; Q7Z2X0; Q96DL0; Q9Y2V1"	""	"VEGFA-VEGFR2 signaling"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WV74"	"Nucleoside diphosphate-linked moiety X motif 8 OS=Homo sapiens OX=9606 GN=NUDT8 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"236"	"25.4"	"8.41"	"270.51"	""	"1"	""	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00293"	"254552"	"ENSG00000167799"	"NUDT8"	"hsa:254552; Q6ZW59; Q8WV74"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94953"	"Lysine-specific demethylase 4B OS=Homo sapiens OX=9606 GN=KDM4B PE=1 SV=4"	"0.000"	""	"1"	"1"	"1"	"1"	"1096"	"121.8"	"7.09"	"269.24"	""	"1"	""	"cell organization and biogenesis;developmental processes"	"nucleus"	"other molecular function"	"Pf02373, Pf02375, Pf13831, Pf13832, Pf18104"	"23030"	"ENSG00000127663"	"KDM4B"	"B9EGN8; D6W631; hsa:23030; O75274; O94953; Q6P3R5; Q9P1V1; Q9UF40"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Estrogen-dependent gene expression; HDMs demethylate histones"	""	"3"	"0"	"4.3"	"0.0"	"5.3"	"6.1"	"5.2"	"5.2"	"5.0"	"0.0"	"36.3"	"25.9"	"52.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15004"	"PCNA-associated factor OS=Homo sapiens OX=9606 GN=PCLAF PE=1 SV=1"	"0.000"	""	"8"	"1"	"1"	"1"	"111"	"12.0"	"9.83"	"263.68"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15715"	"9768"	"ENSG00000166803"	"PCLAF"	"A6NNU5; A8K3Y3; G9G694; G9G696; hsa:9768; Q15004"	"Termination of translesion DNA synthesis"	""	"1"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"4.1"	"8.9"	"1.4"	"34.2"	"36.5"	"48.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2TAA2"	"Isoamyl acetate-hydrolyzing esterase 1 homolog OS=Homo sapiens OX=9606 GN=IAH1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"248"	"27.6"	"5.30"	"262.95"	""	"1"	""	"other metabolic processes"	""	"other molecular function"	"Pf13472"	"285148"	"ENSG00000134330"	"IAH1"	"B4DMV3; hsa:285148; Q2TAA2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX07"	"tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"287"	"32.5"	"4.74"	"261.72"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf17654"	"54952"	"ENSG00000180098"	"TRNAU1AP"	"hsa:54952; Q86SU7; Q9NX07"	""	""	"0"	"0"	"10.9"	"12.0"	"14.5"	"8.7"	"13.3"	"9.0"	"14.3"	"1.5"	"46.1"	"43.6"	"84.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25788"	"Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"255"	"28.4"	"5.33"	"258.99"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5684"	"ENSG00000100567"	"PSMA3"	"B2RCK6; hsa:5684; P25788; Q86U83; Q8N1D8; Q9BS70"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; ER-Phagosome pathway; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Interleukin-1 signaling; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"62"	"0"	"43.9"	"25.2"	"76.5"	"63.0"	"57.7"	"35.8"	"58.9"	"0.0"	"246.5"	"187.2"	"527.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A0MZ66"	"Shootin-1 OS=Homo sapiens OX=9606 GN=SHTN1 PE=1 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"631"	"71.6"	"5.33"	"258.36"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"57698"	"ENSG00000187164"	"SHTN1"	"A0MZ66; A8MYU7; B3KRD3; B3KRH2; B3KTE0; B3KTJ7; B3KTJ8; B4E3U1; B7Z7Z9; hsa:57698; Q68DG1; Q6PIM5; Q9HCH4; Q9NUV0"	"Recycling pathway of L1"	""	"1"	"0"	"3.6"	"0.0"	"4.9"	"5.4"	"7.5"	"5.9"	"5.6"	"0.0"	"36.7"	"51.7"	"69.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50995"	"Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"505"	"54.4"	"7.65"	"257.38"	""	"1"	""	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00191"	"311"	"ENSG00000122359"	"ANXA11"	"B4DVE7; hsa:311; P50995"	""	""	"0"	"0"	"38.7"	"23.3"	"50.4"	"42.2"	"48.0"	"38.3"	"68.0"	"3.9"	"329.7"	"296.0"	"694.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GM5"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Homo sapiens OX=9606 GN=SMARCD1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"515"	"58.2"	"9.25"	"255.30"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf02201"	"6602"	"ENSG00000066117"	"SMARCD1"	"A6NN27; hsa:6602; Q92924; Q96GM5; Q9Y635"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"6"	"0"	"19.0"	"13.4"	"14.0"	"12.0"	"13.8"	"15.8"	"38.6"	"0.0"	"112.7"	"126.0"	"199.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z589"	"BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1322"	"141.4"	"9.33"	"254.07"	""	"1"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf03735"	"56946"	"ENSG00000158636"	"EMSY"	"B7ZKT8; B7ZKU0; B7ZKU2; hsa:56946; Q17RM7; Q4G109; Q7Z589; Q8NBU6; Q8TE50; Q9H8I9; Q9NRH0"	""	"Mesodermal commitment pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62244"	"40S ribosomal protein S15a OS=Homo sapiens OX=9606 GN=RPS15A PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"130"	"14.8"	"10.13"	"252.78"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00410"	"6210"	"ENSG00000134419"	"RPS15A"	"hsa:6210; P39027; P39031; P62244; Q3MHD9; Q8C023; Q9BV24"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"Cytoplasmic ribosomal proteins"	"19"	"0"	"103.4"	"73.4"	"99.3"	"91.2"	"84.6"	"98.2"	"161.5"	"0.0"	"627.0"	"666.0"	"1393.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09038"	"Fibroblast growth factor 2 OS=Homo sapiens OX=9606 GN=FGF2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"288"	"30.8"	"11.18"	"249.42"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00167"	"2247"	"ENSG00000138685"	"FGF2"	"A4LBB8; hsa:2247; O00527; P09038; P78443; Q16443; Q5PY50; Q7KZ11; Q7KZ72; Q9UC54; Q9UCS5; Q9UCS6"	"PIP3 activates AKT signaling; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RAF/MAP kinase cascade; PI3K Cascade; Interleukin-4 and Interleukin-13 signaling; Syndecan interactions; Signaling by FGFR1 in disease; Signaling by FGFR2 IIIa TM; FGFR1b ligand binding and activation; FGFR2b ligand binding and activation; Activated point mutants of FGFR2; Phospholipase C-mediated cascade: FGFR1; Phospholipase C-mediated cascade; FGFR2; SHC-mediated cascade:FGFR1; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; SHC-mediated cascade:FGFR2; FRS-mediated FGFR2 signaling; Negative regulation of FGFR1 signaling; Negative regulation of FGFR2 signaling; Signaling by FGFR2 in disease; FGFRL1 modulation of FGFR1 signaling; Signaling by activated point mutants of FGFR3; FGFR4 ligand binding and activation; FGFR3c ligand binding and activation; FGFR2c ligand binding and activation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; SHC-mediated cascade:FGFR3; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; SHC-mediated cascade:FGFR4; PI-3K cascade:FGFR4; Negative regulation of FGFR3 signaling; Negative regulation of FGFR4 signaling; Signaling by FGFR3 in disease; Signaling by activated point mutants of FGFR1; FGFR1c ligand binding and activation; POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation; Formation of intermediate mesoderm"	"Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Neural crest differentiation; Cardiac progenitor differentiation; Cardiac hypertrophic response; Pluripotent stem cell differentiation pathway; MECP2 and associated Rett syndrome; Lung fibrosis; MAPK signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Breast cancer pathway; Endochondral ossification; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Endochondral ossification with skeletal dysplasias; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; CCL18 signaling pathway; Regulation of actin cytoskeleton; DYRK1A involvement regarding cell proliferation in brain development; 4p16.3 copy number variation"	"69"	"0"	"16.8"	"21.3"	"22.8"	"15.6"	"19.8"	"22.4"	"34.5"	"0.0"	"563.6"	"650.5"	"1245.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15345"	"Leucine-rich repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=LRRC41 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"812"	"88.6"	"8.38"	"248.59"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	""	"10489"	"ENSG00000132128"	"LRRC41"	"A8K5G8; hsa:10489; Q15345; Q3MJ96; Q5TDF5; Q71RA8; Q9BSM0"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; RHOBTB3 ATPase cycle"	""	"3"	"0"	"11.9"	"4.4"	"13.6"	"17.4"	"14.8"	"5.6"	"14.7"	"0.7"	"71.8"	"70.7"	"140.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IU60"	"m7GpppN-mRNA hydrolase OS=Homo sapiens OX=9606 GN=DCP2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"420"	"48.4"	"8.00"	"248.34"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293, Pf05026"	"167227"	"ENSG00000172795"	"DCP2"	"C9J778; hsa:167227; Q6P2D4; Q7Z5W5; Q8IU60; Q8NBG5"	"mRNA decay by 5' to 3' exoribonuclease; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	""	"5"	"0"	"21.4"	"12.0"	"23.4"	"24.3"	"19.4"	"16.4"	"50.9"	"0.0"	"246.7"	"282.4"	"464.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28289"	"Tropomodulin-1 OS=Homo sapiens OX=9606 GN=TMOD1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"359"	"40.5"	"5.10"	"247.44"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"7111"	"ENSG00000136842"	"TMOD1"	"B2RB77; hsa:7111; P28289; Q5T7W3; Q9BUF1"	"Striated Muscle Contraction"	"Striated muscle contraction pathway; VEGFA-VEGFR2 signaling"	"3"	"0"	"16.1"	"7.7"	"13.0"	"9.7"	"13.9"	"12.9"	"25.3"	"1.6"	"121.9"	"105.6"	"238.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKV8"	"Protein argonaute-2 OS=Homo sapiens OX=9606 GN=AGO2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"859"	"97.1"	"9.19"	"245.42"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02170, Pf02171, Pf08699, Pf16486, Pf16487, Pf16488"	"27161"	"ENSG00000123908"	"AGO2"	"hsa:27161; Q8TCZ5; Q8WV58; Q96ID1; Q9UKV8"	"Estrogen-dependent gene expression; Transcriptional regulation by small RNAs; MicroRNA (miRNA) biogenesis; Pre-NOTCH Transcription and Translation; MAPK6/MAPK4 signaling; TP53 Regulates Metabolic Genes; Ca2+ pathway; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Small interfering RNA (siRNA) biogenesis; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"exRNA mechanism of action and biogenesis; Fragile X syndrome; Male infertility; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"22"	"0"	"4.0"	"0.0"	"4.5"	"5.5"	"3.4"	"2.7"	"18.8"	"1.1"	"27.5"	"21.9"	"51.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVD7"	"Alpha-parvin OS=Homo sapiens OX=9606 GN=PARVA PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"372"	"42.2"	"5.95"	"244.37"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00307"	"55742"	"ENSG00000197702"	"PARVA"	"hsa:55742; Q96C85; Q9HA48; Q9NVD7"	"Localization of the PINCH-ILK-PARVIN complex to focal adhesions; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion"	"5"	"0"	"54.8"	"38.7"	"54.0"	"44.7"	"39.0"	"52.6"	"52.3"	"0.0"	"411.5"	"377.5"	"719.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N2G8"	"GH3 domain-containing protein OS=Homo sapiens OX=9606 GN=GHDC PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"530"	"57.5"	"7.88"	"242.88"	""	"1"	""	""	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03321"	"84514"	"ENSG00000167925"	"GHDC"	"B4DQS4; E9PDB5; hsa:84514; Q8N2G8; Q9BXM6"	"Neutrophil degranulation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TEA6"	"Protein sel-1 homolog 2 OS=Homo sapiens OX=9606 GN=SEL1L2 PE=2 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"688"	"77.9"	"9.23"	"241.72"	""	"1"	""	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi"	""	"Pf08238"	"80343"	"ENSG00000101251"	"SEL1L2"	"B4DXX5; hsa:80343; Q5TEA6"	""	""	"0"	"0"	"17.9"	"9.8"	"30.1"	"25.1"	"20.9"	"21.1"	"23.9"	"0.0"	"931.0"	"1016.4"	"2047.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR12"	"PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"457"	"49.8"	"8.41"	"240.47"	""	"1"	""	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595"	"9260"	"ENSG00000196923"	"PDLIM7"	"hsa:9260; Q14250; Q5XG82; Q6NVZ5; Q96C91; Q9BXB8; Q9BXB9; Q9NR12"	"RET signaling"	"Ebstein-Barr virus LMP1 signaling; GDNF signaling; 5q35 copy number variation"	"4"	"0"	"33.3"	"24.1"	"32.4"	"28.1"	"30.6"	"29.6"	"77.7"	"0.0"	"300.2"	"282.7"	"403.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVS4"	"WD repeat-containing protein 60 OS=Homo sapiens OX=9606 GN=WDR60 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1066"	"122.5"	"7.31"	"240.30"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;other cell component"	"other molecular function"	""	"55112"	"ENSG00000126870"	"DYNC2I1"	"hsa:55112; Q8WVS4; Q9NW58"	"Intraflagellar transport"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; 3q29 copy number variation syndrome; Bardet-Biedl syndrome"	"7"	"0"	"61.9"	"50.4"	"77.2"	"52.2"	"81.2"	"64.1"	"121.5"	"0.0"	"344.7"	"339.0"	"613.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UM54"	"Unconventional myosin-VI OS=Homo sapiens OX=9606 GN=MYO6 PE=1 SV=4"	"0.000"	""	"1"	"1"	"1"	"1"	"1294"	"149.6"	"8.53"	"238.72"	""	"1"	""	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf16521"	"4646"	"ENSG00000196586"	"MYO6"	"A6H8V4; E1P540; hsa:4646; Q5TEM5; Q5TEM6; Q5TEM7; Q9BZZ7; Q9UEG2; Q9UM54"	"RHOU GTPase cycle; Gap junction degradation; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; Trafficking of AMPA receptors"	"VEGFA-VEGFR2 signaling; Joubert syndrome"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWW7"	"Uncharacterized protein C2orf42 OS=Homo sapiens OX=9606 GN=C2orf42 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"574"	"64.0"	"8.92"	"236.90"	""	"1"	""	""	"nucleus"	""	"Pf14952"	"54980"	"ENSG00000115998"	"C2orf42"	"D6W5G3; hsa:54980; Q9H629; Q9NWW7"	""	""	"0"	"0"	"207.8"	"52.5"	"340.0"	"226.2"	"282.8"	"183.0"	"96.8"	"0.0"	"287.4"	"210.5"	"630.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0C7P0"	"CDGSH iron-sulfur domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=CISD3 PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"127"	"14.2"	"10.55"	"235.70"	""	"1"	""	"protein metabolism;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf09360"	"284106"	"ENSG00000274768; ENSG00000277972"	"CISD3"	"hsa:284106; P0C7P0"	""	"17q12 copy number variation syndrome"	"1"	"0"	"6.0"	"3.1"	"3.7"	"5.3"	"3.9"	"6.8"	"19.1"	"0.0"	"83.2"	"83.0"	"140.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8H0"	"Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"719"	"81.1"	"6.07"	"235.36"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf08168"	"25926"	"ENSG00000130935"	"NOL11"	"B7Z5V9; hsa:25926; Q7L5S1; Q9H8H0; Q9UG18"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41743"	"Protein kinase C iota type OS=Homo sapiens OX=9606 GN=PRKCI PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"596"	"68.2"	"5.85"	"233.54"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433, Pf00564"	"5584"	"ENSG00000163558"	"PRKCI"	"D3DNQ4; hsa:5584; P41743; Q8WW06"	"Tight junction interactions; Pre-NOTCH Transcription and Translation; p75NTR recruits signalling complexes"	"Glioblastoma signaling pathways; Corticotropin-releasing hormone signaling pathway; G protein signaling pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; EGF/EGFR signaling pathway; Hippo signaling regulation pathways; Osteoblast differentiation and related diseases; Insulin signaling; Complement system in neuronal development and plasticity; Chronic hyperglycemia impairment of neuron function"	"14"	"0"	"141.3"	"111.0"	"113.8"	"116.9"	"105.1"	"108.2"	"174.6"	"0.0"	"756.4"	"869.2"	"1928.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99741"	"Cell division control protein 6 homolog OS=Homo sapiens OX=9606 GN=CDC6 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"560"	"62.7"	"9.58"	"233.40"	""	"1"	""	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf09079, Pf13401, Pf17872"	"990"	"ENSG00000094804"	"CDC6"	"hsa:990; Q8TB30; Q99741"	"Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; CDC6 association with the ORC:origin complex; G1/S-Specific Transcription; Transcription of E2F targets under negative control by DREAM complex"	"Cell cycle; DNA replication"	"10"	"0"	"55.4"	"32.0"	"47.3"	"46.3"	"43.8"	"51.2"	"49.7"	"0.0"	"304.5"	"276.8"	"594.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DY2"	"Dynein regulatory complex protein 10 OS=Homo sapiens OX=9606 GN=IQCD PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"449"	"52.3"	"9.25"	"233.04"	""	"1"	""	""	"cytoskeleton;other cell component"	""	"Pf00612"	"115811"	"ENSG00000166578"	"IQCD"	"hsa:115811; Q6ZSU0; Q96DY2"	""	""	"0"	"0"	"44.3"	"34.9"	"48.9"	"44.9"	"33.4"	"42.0"	"95.0"	"0.0"	"546.9"	"535.3"	"1242.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08243"	"Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4"	"0.000"	""	"1"	"1"	"1"	"1"	"561"	"64.3"	"6.86"	"231.15"	""	"1"	""	"other metabolic processes;stress response;other biological processes"	"cytosol"	"other molecular function"	"Pf00733, Pf13537"	"440"	"ENSG00000070669"	"ASNS"	"A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; hsa:440; P08184; P08243; Q15666; Q549T9; Q96HD0"	"Aspartate and asparagine metabolism; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00491"	"Purine nucleoside phosphorylase OS=Homo sapiens OX=9606 GN=PNP PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"289"	"32.1"	"6.95"	"230.95"	""	"1"	""	"other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01048"	"4860"	"ENSG00000198805"	"PNP"	"B2R8S5; D3DS00; hsa:4860; P00491; Q15160; Q5PZ03"	"Neutrophil degranulation; Purine catabolism; Ribavirin ADME; Purine salvage; Defective PNP disrupts phosphorolysis of (deoxy)guanosine and (deoxy)inosine"	"VEGFA-VEGFR2 signaling"	"6"	"0"	"41.3"	"44.9"	"101.9"	"58.0"	"44.2"	"46.1"	"60.4"	"0.0"	"303.4"	"347.2"	"1355.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N7P1"	"Inactive phospholipase D5 OS=Homo sapiens OX=9606 GN=PLD5 PE=2 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"536"	"61.3"	"8.72"	"230.51"	""	"1"	""	""	"other membranes;other cell component"	"other molecular function"	"Pf13918"	"200150"	"ENSG00000180287"	"PLD5"	"A1KXV0; B7Z324; hsa:200150; Q494U9; Q8N7P1; Q8NB22"	""	""	"0"	"0"	"21.1"	"27.8"	"12.5"	"49.0"	"24.1"	"24.7"	"59.1"	"0.0"	"184.1"	"819.1"	"111.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93008"	"Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=3"	"0.000"	""	"0"	"1"	"1"	"1"	"2570"	"292.1"	"5.80"	"229.72"	""	"1"	""	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf00443, Pf12030"	"100971796; 465582"	"ENSPPAG00000039671; ENSPTRG00000045541"	"USP9X"	"A0A2I3RAB4; A0A2J8JDU7; A0A2R9BVD0; A0A6D2WW26"	""	""	"0"	"0"	"130.3"	"94.1"	"101.4"	"94.1"	"123.7"	"83.5"	"186.9"	"0.0"	"524.2"	"592.4"	"986.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6J0"	"Calcineurin-binding protein cabin-1 OS=Homo sapiens OX=9606 GN=CABIN1 PE=1 SV=1"	"0.000"	""	"0"	"1"	"1"	"1"	"2220"	"246.2"	"6.02"	"229.16"	""	"1"	""	"cell organization and biogenesis;signal transduction"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf09047"	"23523"	"ENSG00000099991"	"CABIN1"	"G5E9F3; hsa:23523; Q6PHY0; Q9Y460; Q9Y6J0"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	""	"1"	"0"	"12.3"	"8.4"	"14.2"	"16.8"	"12.1"	"7.9"	"19.8"	"0.0"	"159.0"	"179.6"	"312.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13049"	"E3 ubiquitin-protein ligase TRIM32 OS=Homo sapiens OX=9606 GN=TRIM32 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"653"	"71.9"	"6.98"	"228.91"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01436, Pf13445"	"22954"	"ENSG00000119401"	"TRIM32"	"hsa:22954; Q13049; Q9NQP8"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of innate immune responses to cytosolic DNA"	"Ciliopathies; Bardet-Biedl syndrome"	"4"	"0"	"6.1"	"0.0"	"0.0"	"4.1"	"0.0"	"2.6"	"6.7"	"0.2"	"79.2"	"94.8"	"142.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PGP7"	"Tetratricopeptide repeat protein 37 OS=Homo sapiens OX=9606 GN=TTC37 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"1564"	"175.4"	"7.53"	"226.17"	""	"1"	""	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf13181, Pf13432"	"9652"	"ENSG00000198677"	"SKIC3"	"hsa:9652; O15077; Q6PGP7; Q6PJI3"	"mRNA decay by 3' to 5' exoribonuclease"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13056"	"Nuclear receptor subfamily 2 group C member 1 OS=Homo sapiens OX=9606 GN=NR2C1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"603"	"67.3"	"6.32"	"225.72"	""	"1"	""	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00104, Pf00105"	"7181"	"ENSG00000120798"	"NR2C1"	"A8K5K4; hsa:7181; P13056; Q15625; Q15626"	"Nuclear Receptor transcription pathway; SUMOylation of intracellular receptors"	""	"2"	"0"	"14.0"	"9.5"	"16.9"	"14.9"	"7.7"	"10.3"	"29.8"	"1.6"	"255.6"	"259.3"	"390.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92979"	"Ribosomal RNA small subunit methyltransferase NEP1 OS=Homo sapiens OX=9606 GN=EMG1 PE=1 SV=4"	"0.000"	""	"5"	"1"	"1"	"1"	"244"	"26.7"	"9.17"	"225.17"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03587"	"10436"	"ENSG00000126749"	"EMG1"	"hsa:10436; O00675; O00726; Q92979"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	""	"2"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"8.6"	"0.0"	"34.3"	"36.9"	"85.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15014"	"Zinc finger protein 609 OS=Homo sapiens OX=9606 GN=ZNF609 PE=1 SV=2"	"0.000"	""	"0"	"1"	"1"	"1"	"1411"	"151.1"	"8.03"	"224.54"	""	"1"	""	"other biological processes"	"nucleus"	"other molecular function"	""	"23060"	"ENSG00000180357"	"ZNF609"	"hsa:23060; O15014; Q0D2I2"	""	""	"0"	"0"	"19.4"	"16.3"	"16.7"	"24.5"	"22.0"	"23.6"	"38.5"	"0.0"	"154.3"	"153.5"	"300.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTQ0"	"Tetratricopeptide repeat protein 39B OS=Homo sapiens OX=9606 GN=TTC39B PE=1 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"682"	"76.9"	"7.39"	"222.78"	""	"1"	""	"other metabolic processes;other biological processes"	""	""	"Pf10300"	"158219"	"ENSG00000155158"	"TTC39B"	"A5PLN1; B4DQ10; B4DQX4; B4DW93; hsa:158219; Q5VTQ0; Q8IVR7; Q8IXZ6; Q8N267"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86SQ9"	"Dehydrodolichyl diphosphate synthase complex subunit DHDDS OS=Homo sapiens OX=9606 GN=DHDDS PE=1 SV=3"	"0.000"	""	"3"	"1"	"1"	"1"	"333"	"38.6"	"8.28"	"222.61"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01255"	"79947"	"ENSG00000117682"	"DHDDS"	"B7Z4B9; B7ZB20; D3DPK7; D3DPK8; D3DPK9; E9KL43; hsa:79947; Q5T0A4; Q86SQ9; Q8NE90; Q9BTG5; Q9BTK3; Q9H905"	"Synthesis of Dolichyl-phosphate; Defective DHDDS causes RP59"	""	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TE73"	"Dynein heavy chain 5, axonemal OS=Homo sapiens OX=9606 GN=DNAH5 PE=1 SV=3"	"0.000"	""	"0"	"1"	"1"	"1"	"4624"	"528.7"	"6.10"	"221.59"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf17857, Pf18198, Pf18199"	"1767"	"ENSG00000039139"	"DNAH5"	"hsa:1767; Q8TE73; Q92860; Q96L74; Q9H5S7; Q9HCG9"	""	""	"0"	"0"	"22.8"	"17.2"	"28.9"	"26.8"	"18.2"	"19.3"	"62.0"	"4.6"	"576.3"	"516.0"	"1455.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""