"Checked"	"Protein FDR Confidence: MS Amanda 2.0"	"Protein FDR Confidence: Sequest HT"	"Master"	"Accession"	"Description"	"Exp. q-value: MS Amanda 2.0"	"Exp. q-value: Sequest HT"	"Coverage [%]"	"# Peptides"	"# PSMs"	"# Unique Peptides"	"# AAs"	"MW [kDa]"	"calc. pI"	"Score MS Amanda 2.0: MS Amanda 2.0"	"Score Sequest HT: Sequest HT"	"# Peptides (by Search Engine): MS Amanda 2.0"	"# Peptides (by Search Engine): Sequest HT"	"Biological Process"	"Cellular Component"	"Molecular Function"	"Pfam IDs"	"Entrez Gene ID"	"Ensembl Gene ID"	"Gene Symbol"	"Gene ID"	"WikiPathways"	"Reactome Pathways"	"# Protein Pathway Groups"	"# Razor Peptides"	"Abundances (Grouped): 126"	"Abundances (Grouped): 127N"	"Abundances (Grouped): 127C"	"Abundances (Grouped): 128N"	"Abundances (Grouped): 128C"	"Abundances (Grouped): 129N"	"Abundances (Grouped): 129C"	"Abundances (Grouped): 130N"	"Abundances (Grouped): 130C"	"Abundances (Grouped): 131N"	"Abundances (Grouped): 131C"	"Abundances (Grouped) CV [%]: 126"	"Abundances (Grouped) CV [%]: 127N"	"Abundances (Grouped) CV [%]: 127C"	"Abundances (Grouped) CV [%]: 128N"	"Abundances (Grouped) CV [%]: 128C"	"Abundances (Grouped) CV [%]: 129N"	"Abundances (Grouped) CV [%]: 129C"	"Abundances (Grouped) CV [%]: 130N"	"Abundances (Grouped) CV [%]: 130C"	"Abundances (Grouped) CV [%]: 131N"	"Abundances (Grouped) CV [%]: 131C"	"Found in Sample: F7: 126, Sample"	"Found in Sample: F7: 127N, Sample"	"Found in Sample: F7: 127C, Sample"	"Found in Sample: F7: 128N, Sample"	"Found in Sample: F7: 128C, Sample"	"Found in Sample: F7: 129N, Sample"	"Found in Sample: F7: 129C, Sample"	"Found in Sample: F7: 130N, Sample"	"Found in Sample: F7: 130C, Sample"	"Found in Sample: F7: 131N, Sample"	"Found in Sample: F7: 131C, Sample"	"# Protein Groups"	"Modifications"
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13813"	"Spectrin alpha chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTAN1 PE=1 SV=3"	"0.000"	""	"56"	"136"	"326"	"136"	"2472"	"284.4"	"5.35"	"64364.60"	"721.03"	"109"	"126"	"cell organization and biogenesis"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00435, Pf08726, Pf13499"	"6709"	"ENSG00000197694"	"SPTAN1"	"hsa:6709; Q13186; Q13813; Q15324; Q16606; Q59EF1; Q5VXV5; Q5VXV6; Q7Z6M5; Q9P0V0"	"Fas ligand pathway and stress induction of heat shock proteins"	"Neutrophil degranulation; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Interaction between L1 and Ankyrins; RHOV GTPase cycle; COPI-mediated anterograde transport; RHOU GTPase cycle; Nephrin family interactions; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Caspase-mediated cleavage of cytoskeletal proteins"	"12"	"0"	"6021.5"	"5273.2"	"6588.9"	"7953.1"	"5560.3"	"5845.9"	"23339.5"	"25407.1"	"54186.1"	"101903.0"	"115206.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01082"	"Spectrin beta chain, non-erythrocytic 1 OS=Homo sapiens OX=9606 GN=SPTBN1 PE=1 SV=2"	"0.000"	""	"51"	"108"	"277"	"95"	"2364"	"274.4"	"5.57"	"57856.52"	"560.61"	"95"	"98"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00435"	"6711"	"ENSG00000115306"	"SPTBN1"	"B2RP63; hsa:6711; O60837; Q01082; Q16057; Q53R99; Q59ER3; Q8IX99"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Signaling by FLT3 fusion proteins; COPI-mediated anterograde transport; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; Interaction between L1 and Ankyrins"	"11"	"14"	"3285.0"	"2947.1"	"3908.8"	"4976.2"	"3295.5"	"3362.4"	"13656.2"	"14928.1"	"34794.7"	"67320.1"	"77436.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20700"	"Lamin-B1 OS=Homo sapiens OX=9606 GN=LMNB1 PE=1 SV=2"	"0.000"	""	"75"	"62"	"190"	"54"	"586"	"66.4"	"5.16"	"34370.41"	"406.13"	"53"	"57"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf00932"	"4001"	"ENSG00000113368"	"LMNB1"	"B2R6J6; hsa:4001; P20700; Q3SYN7; Q96EI6"	"Fas ligand pathway and stress induction of heat shock proteins; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	"Meiotic synapsis; RHOD GTPase cycle; RHOF GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; Breakdown of the nuclear lamina; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"14"	"9"	"9496.8"	"8940.2"	"9668.2"	"13208.5"	"7615.7"	"7885.5"	"13153.6"	"13328.2"	"16774.5"	"36216.2"	"43594.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXH0"	"Nesprin-2 OS=Homo sapiens OX=9606 GN=SYNE2 PE=1 SV=3"	"0.000"	""	"15"	"88"	"164"	"86"	"6885"	"795.9"	"5.36"	"29468.13"	"324.99"	"73"	"83"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23224"	"ENSG00000054654"	"SYNE2"	"B4DND7; B4DPR6; hsa:23224; I6XXQ5; Q540G1; Q86YP9; Q8N1S3; Q8NF49; Q8TER7; Q8WWW3; Q8WWW4; Q8WWW5; Q8WXH0; Q8WXH1; Q9NU50; Q9UFQ4; Q9Y2L4; Q9Y4R1"	"Ovarian infertility; Rett syndrome causing genes; Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"4"	"1"	"1921.6"	"1626.5"	"2349.6"	"2659.2"	"1924.4"	"2003.4"	"6492.2"	"7225.7"	"12940.1"	"37671.7"	"48040.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12270"	"Nucleoprotein TPR OS=Homo sapiens OX=9606 GN=TPR PE=1 SV=3"	"0.000"	""	"30"	"68"	"154"	"67"	"2363"	"267.1"	"5.02"	"34903.68"	"285.24"	"65"	"61"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf07926"	"7175"	"ENSG00000047410"	"TPR"	"hsa:7175; P12270; Q15624; Q15655; Q5SWY0; Q99968"	""	"HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Signaling by ALK fusions and activated point mutants"	"29"	"1"	"6264.5"	"5427.3"	"6147.1"	"7141.2"	"5556.0"	"5901.8"	"9307.7"	"9529.8"	"12475.4"	"33850.4"	"51903.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13639"	"Elongation factor 2 OS=Homo sapiens OX=9606 GN=EEF2 PE=1 SV=4"	"0.000"	""	"46"	"44"	"119"	"44"	"858"	"95.3"	"6.83"	"23523.54"	"261.59"	"36"	"38"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"1938"	"ENSG00000167658"	"EEF2"	"A0A384N6H1; B2RMP5; D6W618; hsa:1938; P13639; Q58J86"	"Translation factors; AMP-activated protein kinase signaling; Brain-derived neurotrophic factor (BDNF) signaling pathway; IL-18 signaling pathway"	"Neutrophil degranulation; Protein methylation; Uptake and function of diphtheria toxin; Peptide chain elongation; Synthesis of diphthamide-EEF2"	"9"	"0"	"1161.1"	"1026.8"	"1467.8"	"1715.6"	"1184.9"	"1243.4"	"4446.2"	"5081.1"	"10612.9"	"34474.9"	"47825.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08670"	"Vimentin OS=Homo sapiens OX=9606 GN=VIM PE=1 SV=4"	"0.000"	""	"68"	"46"	"127"	"44"	"466"	"53.6"	"5.12"	"24397.10"	"255.50"	"37"	"45"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00038, Pf04732"	"7431"	"ENSG00000026025"	"VIM"	"B0YJC2; D3DRU4; hsa:7431; P08670; Q15867; Q15868; Q15869; Q548L2; Q6LER9; Q8N850; Q96ML2; Q9NTM3"	"Allograft rejection; Spinal cord injury; Primary focal segmental glomerulosclerosis (FSGS); Mammary gland development pathway - Puberty (Stage 2 of 4); Apoptosis-related network due to altered Notch3 in ovarian cancer; Striated muscle contraction pathway; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Ciliary landscape; Burn wound healing; CCL18 signaling pathway; TROP2 regulatory signaling; CKAP4 signaling pathway map; A network map of Macrophage-stimulating protein (MSP) signaling; T-cell receptor signaling pathway"	"Aggrephagy; Interleukin-4 and Interleukin-13 signaling; Chaperone Mediated Autophagy; Late endosomal microautophagy; Striated Muscle Contraction; RHOBTB1 GTPase cycle; Caspase-mediated cleavage of cytoskeletal proteins"	"21"	"3"	"5183.2"	"5044.5"	"4861.4"	"6079.6"	"3981.1"	"4495.1"	"7135.2"	"7144.0"	"8582.2"	"17052.2"	"21892.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22626"	"Heterogeneous nuclear ribonucleoproteins A2/B1 OS=Homo sapiens OX=9606 GN=HNRNPA2B1 PE=1 SV=2"	"0.000"	""	"72"	"27"	"105"	"24"	"353"	"37.4"	"8.95"	"17442.89"	"251.77"	"20"	"25"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3181"	"ENSG00000122566"	"HNRNPA2B1"	"A0A024RA27; A0A024RA61; A8K064; hsa:3181; P22626; P22627; Q9UC98; Q9UDJ2"	"mRNA processing"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"3"	"8120.3"	"9440.4"	"8850.0"	"10890.2"	"7437.1"	"7266.5"	"10600.5"	"10885.5"	"11288.7"	"17675.1"	"24325.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15020"	"Spectrin beta chain, non-erythrocytic 2 OS=Homo sapiens OX=9606 GN=SPTBN2 PE=1 SV=3"	"0.000"	""	"27"	"54"	"125"	"44"	"2390"	"271.2"	"6.11"	"26972.75"	"230.22"	"49"	"48"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf15410"	"6712"	"ENSG00000173898"	"SPTBN2"	"hsa:6712; O14872; O14873; O15020"	""	"MHC class II antigen presentation; COPI-mediated anterograde transport; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins"	"5"	"0"	"1476.9"	"1283.3"	"1697.1"	"1979.3"	"1402.6"	"1470.0"	"3998.1"	"4417.5"	"8271.1"	"22079.6"	"26507.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02545"	"Prelamin-A/C OS=Homo sapiens OX=9606 GN=LMNA PE=1 SV=1"	"0.000"	""	"59"	"51"	"120"	"50"	"664"	"74.1"	"7.02"	"21860.83"	"222.63"	"44"	"49"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"4000"	"ENSG00000160789"	"LMNA"	"B4DI32; D3DVB0; D6RAQ3; E7EUI9; hsa:4000; P02545; P02546; Q5I6Y4; Q5I6Y6; Q5TCJ2; Q5TCJ3; Q6UYC3; Q969I8; Q96JA2"	"Arrhythmogenic right ventricular cardiomyopathy; Adipogenesis; Fas ligand pathway and stress induction of heat shock proteins; Lamin A-processing pathway; Nephrotic syndrome; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome; Primary ovarian insufficiency"	"XBP1(S) activates chaperone genes; Signaling by BRAF and RAF1 fusions"	"13"	"0"	"5559.5"	"4871.1"	"5890.3"	"8182.7"	"4894.6"	"5253.6"	"8985.2"	"8968.3"	"11316.2"	"22907.0"	"25967.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03252"	"Lamin-B2 OS=Homo sapiens OX=9606 GN=LMNB2 PE=1 SV=4"	"0.000"	""	"62"	"48"	"124"	"40"	"620"	"69.9"	"5.59"	"22315.47"	"218.48"	"43"	"45"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf00932"	"84823"	"ENSG00000176619"	"LMNB2"	"hsa:84823; O75292; Q03252; Q14734; Q96DF6"	"Gastric cancer network 2; Fas ligand pathway and stress induction of heat shock proteins; IL-18 signaling pathway; Familial partial lipodystrophy; Progeria-associated lipodystrophy; Acquired partial lipodystrophy / Barraquer-Simons syndrome"	""	"6"	"0"	"4995.0"	"4429.2"	"5037.4"	"7044.2"	"4259.8"	"4472.9"	"6800.5"	"6992.6"	"8961.8"	"18461.3"	"22750.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQE7"	"Structural maintenance of chromosomes protein 3 OS=Homo sapiens OX=9606 GN=SMC3 PE=1 SV=2"	"0.000"	""	"43"	"56"	"120"	"55"	"1217"	"141.5"	"7.18"	"24729.81"	"217.51"	"51"	"48"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"9126"	"ENSG00000108055"	"SMC3"	"A8K156; hsa:9126; O60464; Q5T482; Q9UQE7"	"Cell cycle; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"15"	"1"	"5728.3"	"5104.5"	"5807.4"	"6864.2"	"5144.2"	"5551.2"	"9540.6"	"9948.2"	"13781.2"	"30948.0"	"38721.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09666"	"Neuroblast differentiation-associated protein AHNAK OS=Homo sapiens OX=9606 GN=AHNAK PE=1 SV=2"	"0.000"	""	"23"	"48"	"108"	"48"	"5890"	"628.7"	"6.15"	"20836.83"	"215.20"	"40"	"46"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"79026"	"ENSG00000124942"	"AHNAK"	"A1A586; hsa:79026; Q09666"	""	""	"0"	"0"	"1985.5"	"1493.1"	"2245.3"	"2726.2"	"1640.4"	"1863.4"	"4017.5"	"4414.7"	"7503.6"	"17633.9"	"24696.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08133"	"Annexin A6 OS=Homo sapiens OX=9606 GN=ANXA6 PE=1 SV=3"	"0.000"	""	"52"	"33"	"87"	"33"	"673"	"75.8"	"5.60"	"14518.06"	"202.81"	"20"	"33"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;cytoskeletal activity;other molecular function"	"Pf00191"	"309"	"ENSG00000197043"	"ANXA6"	"B7Z8A7; D3DQH4; E9PGK1; hsa:309; P08133; Q6ZT79"	"Calcium regulation in cardiac cells; Prostaglandin synthesis and regulation"	"Smooth Muscle Contraction"	"3"	"0"	"671.5"	"628.9"	"825.0"	"1068.5"	"724.2"	"755.3"	"1748.7"	"1882.4"	"2943.0"	"24938.8"	"53408.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14683"	"Structural maintenance of chromosomes protein 1A OS=Homo sapiens OX=9606 GN=SMC1A PE=1 SV=2"	"0.000"	""	"45"	"59"	"120"	"58"	"1233"	"143.1"	"7.64"	"21865.98"	"201.21"	"54"	"51"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"8243"	"ENSG00000072501"	"SMC1A"	"hsa:8243; O14995; Q14683; Q16351; Q2M228"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; mRNA processing; Regulation of sister chromatid separation at the metaphase-anaphase transition; Rett syndrome causing genes; CAMKK2 pathway; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation; DNA damage response"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Estrogen-dependent gene expression; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"22"	"1"	"5318.3"	"5048.4"	"5834.8"	"6505.6"	"5019.0"	"5306.1"	"9317.6"	"9528.1"	"13373.9"	"29564.2"	"36229.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00839"	"Heterogeneous nuclear ribonucleoprotein U OS=Homo sapiens OX=9606 GN=HNRNPU PE=1 SV=6"	"0.000"	""	"45"	"37"	"99"	"36"	"825"	"90.5"	"6.00"	"19333.69"	"195.91"	"22"	"32"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00622, Pf02037, Pf13671"	"3192"	"ENSG00000153187"	"HNRNPU"	"hsa:3192; O75507; Q00839; Q8N174; Q96HY9; Q9BQ09"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"1"	"5931.6"	"6250.5"	"6855.1"	"8531.9"	"5598.1"	"5742.6"	"9113.3"	"9525.0"	"11131.8"	"18654.3"	"35210.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15149"	"Plectin OS=Homo sapiens OX=9606 GN=PLEC PE=1 SV=3"	"0.000"	""	"14"	"51"	"89"	"48"	"4684"	"531.5"	"5.96"	"14972.19"	"193.74"	"37"	"49"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00681, Pf03501, Pf17902, Pf18373"	"5339"	"ENSG00000178209"	"PLEC"	"hsa:5339; Q15148; Q15149; Q16640; Q6S376; Q6S377; Q6S378; Q6S379; Q6S380; Q6S381; Q6S382; Q6S383"	"Envelope proteins and their potential roles in EDMD physiopathology"	"Assembly of collagen fibrils and other multimeric structures; Caspase-mediated cleavage of cytoskeletal proteins; Type I hemidesmosome assembly"	"4"	"3"	"2742.0"	"2462.8"	"3093.8"	"3881.3"	"2648.2"	"2627.9"	"4244.8"	"4423.7"	"5377.4"	"12602.4"	"19110.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75643"	"U5 small nuclear ribonucleoprotein 200 kDa helicase OS=Homo sapiens OX=9606 GN=SNRNP200 PE=1 SV=2"	"0.000"	""	"28"	"46"	"83"	"46"	"2136"	"244.4"	"6.06"	"15647.75"	"180.06"	"35"	"41"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf02889, Pf18149"	"23020"	"ENSG00000144028"	"SNRNP200"	"hsa:23020; O75643; O94884; Q6NZY0; Q6PX59; Q8NBE6; Q96IF2; Q9H7S0"	"2q11.2 copy number variation syndrome"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1847.0"	"1718.2"	"1996.3"	"2599.4"	"1684.7"	"1738.1"	"3110.1"	"3201.9"	"4323.0"	"15280.8"	"27758.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P2Q9"	"Pre-mRNA-processing-splicing factor 8 OS=Homo sapiens OX=9606 GN=PRPF8 PE=1 SV=2"	"0.000"	""	"21"	"41"	"81"	"41"	"2335"	"273.4"	"8.84"	"13989.33"	"173.24"	"33"	"38"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf08082, Pf08083, Pf08084, Pf10596, Pf10597, Pf10598, Pf12134"	"10594"	"ENSG00000174231; ENSG00000274442"	"PRPF8"	"hsa:10594; O14547; O75965; Q6P2Q9"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1927.6"	"1856.3"	"2253.7"	"2997.8"	"1884.3"	"1850.1"	"3265.1"	"3471.2"	"4511.4"	"17391.1"	"31120.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14980"	"Nuclear mitotic apparatus protein 1 OS=Homo sapiens OX=9606 GN=NUMA1 PE=1 SV=2"	"0.000"	""	"22"	"42"	"83"	"41"	"2115"	"238.1"	"5.78"	"17322.12"	"164.75"	"38"	"38"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"4926"	"ENSG00000137497"	"NUMA1"	"H0YH75; hsa:4926; Q14980; Q14981; Q9BTE9"	"Ectoderm differentiation; Ectoderm differentiation; 8p23.1 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Mitotic Prophase"	"5"	"0"	"2790.3"	"2459.1"	"2843.7"	"3618.9"	"2559.5"	"2537.7"	"3849.1"	"4045.7"	"4840.8"	"10442.7"	"15252.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11142"	"Heat shock cognate 71 kDa protein OS=Homo sapiens OX=9606 GN=HSPA8 PE=1 SV=1"	"0.000"	""	"49"	"32"	"85"	"25"	"646"	"70.9"	"5.52"	"15000.80"	"154.85"	"28"	"30"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3312"	"ENSG00000109971"	"HSPA8"	"hsa:3312; P11142; Q9H3R6"	"Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Exercise-induced circadian regulation; Measles virus infection; Opioid receptor pathways; Extrafollicular and follicular B cell activation by SARS-CoV-2; 1p36 copy number variation syndrome"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Neutrophil degranulation; mRNA Splicing - Major Pathway; Golgi Associated Vesicle Biogenesis; Late endosomal microautophagy; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Lysosome Vesicle Biogenesis; Clathrin-mediated endocytosis; CHL1 interactions; Interleukin-4 and Interleukin-13 signaling; GABA synthesis, release, reuptake and degradation; Lipophagy; Chaperone Mediated Autophagy; Protein methylation; Attenuation phase"	"24"	"8"	"3272.2"	"2767.9"	"3666.4"	"4577.0"	"2809.4"	"3108.5"	"5110.4"	"5183.0"	"7155.2"	"16847.0"	"23643.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61978"	"Heterogeneous nuclear ribonucleoprotein K OS=Homo sapiens OX=9606 GN=HNRNPK PE=1 SV=1"	"0.000"	""	"50"	"24"	"76"	"24"	"463"	"50.9"	"5.54"	"15067.05"	"153.11"	"20"	"22"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf08067"	"3190"	"ENSG00000165119"	"HNRNPK"	"hsa:3190; P61978; Q07244; Q15671; Q59F98; Q5T6W4; Q60577; Q6IBN1; Q922Y7; Q96J62"	"mRNA processing; lncRNA in canonical Wnt signaling and colorectal cancer"	"mRNA Splicing - Major Pathway; HCMV Late Events; SUMOylation of RNA binding proteins; Processing of Capped Intron-Containing Pre-mRNA"	"6"	"0"	"3596.1"	"3552.8"	"4396.8"	"5988.0"	"3378.4"	"3523.7"	"6169.8"	"6253.0"	"7977.0"	"17429.2"	"28037.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08211"	"ATP-dependent RNA helicase A OS=Homo sapiens OX=9606 GN=DHX9 PE=1 SV=4"	"0.000"	""	"31"	"30"	"69"	"30"	"1270"	"140.9"	"6.84"	"14381.98"	"147.78"	"25"	"27"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00035, Pf00270, Pf00271, Pf04408, Pf07717"	"1660"	"ENSG00000135829"	"DHX9"	"B2RNV4; hsa:1660; Q05CI5; Q08211; Q12803; Q32Q22; Q5VY62; Q6PD69; Q99556"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; RIP-mediated NFkB activation via ZBP1; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"5"	"0"	"1610.3"	"1754.8"	"1880.6"	"2516.4"	"1575.4"	"1501.6"	"2830.3"	"3089.4"	"3996.1"	"10136.3"	"15882.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38646"	"Stress-70 protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPA9 PE=1 SV=2"	"0.000"	""	"47"	"31"	"62"	"30"	"679"	"73.6"	"6.16"	"11003.41"	"143.94"	"25"	"30"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00012"	"3313"	"ENSG00000113013"	"HSPA9"	"B2RCM1; hsa:3313; P30036; P31932; P38646; Q1HB43; Q53H23; Q6GU03; Q9BWB7; Q9UC56"	"Parkin-ubiquitin proteasomal system pathway; Iron-sulfur cluster biogenesis"	"Mitochondrial protein import; Regulation of HSF1-mediated heat shock response; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Cristae formation"	"6"	"0"	"3719.5"	"3336.0"	"4183.1"	"5316.8"	"3341.4"	"3354.2"	"5975.7"	"6218.3"	"7685.1"	"15704.2"	"20536.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26639"	"Threonine--tRNA ligase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS1 PE=1 SV=3"	"0.000"	""	"46"	"33"	"69"	"31"	"723"	"83.4"	"6.67"	"11792.47"	"143.39"	"25"	"30"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"6897"	"ENSG00000113407"	"TARS1"	"A8K8I1; B4DEG8; hsa:6897; P26639; Q96FP5; Q9BWA6"	""	"Cytosolic tRNA aminoacylation"	"1"	"2"	"577.5"	"517.8"	"736.3"	"873.8"	"585.1"	"733.5"	"3812.3"	"4524.9"	"7329.9"	"18629.2"	"26498.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31943"	"Heterogeneous nuclear ribonucleoprotein H OS=Homo sapiens OX=9606 GN=HNRNPH1 PE=1 SV=4"	"0.000"	""	"41"	"18"	"61"	"9"	"449"	"49.2"	"6.30"	"9697.57"	"142.44"	"12"	"18"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08080"	"3187"	"ENSG00000169045; ENSG00000284254"	"HNRNPH1"	"B3KW86; D3DWQ2; hsa:3187; P31943; Q6IBM4"	"MECP2 and associated Rett syndrome; mRNA processing; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA"	"6"	"10"	"3492.7"	"4508.0"	"3102.7"	"4439.7"	"2779.4"	"3038.8"	"4970.4"	"5239.8"	"6393.0"	"12568.4"	"14975.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04406"	"Glyceraldehyde-3-phosphate dehydrogenase OS=Homo sapiens OX=9606 GN=GAPDH PE=1 SV=3"	"0.000"	""	"64"	"22"	"51"	"22"	"335"	"36.0"	"8.46"	"7291.96"	"141.09"	"14"	"20"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00044, Pf02800"	"2597"	"ENSG00000111640"	"GAPDH"	"E7EUT4; hsa:2597; P00354; P04406; Q53X65"	"Cori cycle; Alzheimer's disease and miRNA effects; HIF1A and PPARG regulation of glycolysis; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; 7q11.23 copy number variation syndrome; Glycolysis in senescence; Alzheimer's disease; Sildenafil treatment; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis"	"16"	"0"	"2181.6"	"2156.5"	"2171.7"	"2961.6"	"1755.0"	"2034.9"	"3236.2"	"3394.9"	"4138.4"	"7684.4"	"10880.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43491"	"Band 4.1-like protein 2 OS=Homo sapiens OX=9606 GN=EPB41L2 PE=1 SV=1"	"0.000"	""	"34"	"31"	"68"	"27"	"1005"	"112.5"	"5.44"	"12041.25"	"140.92"	"27"	"29"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2037"	"ENSG00000079819"	"EPB41L2"	"B4DHI8; E9PPD9; hsa:2037; O43491; Q5T4F0; Q68DV2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins"	"2"	"4"	"3497.6"	"2987.3"	"3553.9"	"4275.6"	"2896.8"	"3079.2"	"5122.8"	"5249.1"	"6994.6"	"19820.1"	"25652.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49792"	"E3 SUMO-protein ligase RanBP2 OS=Homo sapiens OX=9606 GN=RANBP2 PE=1 SV=2"	"0.000"	""	"16"	"35"	"59"	"23"	"3224"	"358.0"	"6.20"	"9145.03"	"138.58"	"24"	"33"	"protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00160, Pf00638, Pf00641, Pf12185"	"5903"	"ENSG00000153201"	"RANBP2"	"hsa:5903; P49792; Q13074; Q15280; Q53TE2; Q59FH7"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; SUMOylation of DNA damage response and repair proteins; Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Signaling by ALK fusions and activated point mutants"	"35"	"12"	"2990.1"	"2467.9"	"3111.0"	"3522.9"	"2649.1"	"2684.5"	"4109.5"	"4257.0"	"5249.7"	"11534.7"	"16511.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JRX3"	"Presequence protease, mitochondrial OS=Homo sapiens OX=9606 GN=PITRM1 PE=1 SV=3"	"0.000"	""	"31"	"25"	"56"	"25"	"1037"	"117.3"	"6.92"	"10178.52"	"135.96"	"20"	"24"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00675, Pf05193, Pf08367"	"10531"	"ENSG00000107959"	"PITRM1"	"B3KMJ6; B4E0J8; C9JSL2; E7ES23; hsa:10531; O95204; Q2M2G6; Q4VBR1; Q5JRW7; Q5JRX3; Q7L5Z7; Q9BSI6; Q9BVJ5; Q9UPP8"	""	"Mitochondrial protein import"	"1"	"0"	"627.2"	"427.7"	"814.6"	"866.4"	"650.7"	"658.4"	"2801.5"	"3179.9"	"5414.7"	"16110.2"	"22363.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7KZF4"	"Staphylococcal nuclease domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SND1 PE=1 SV=1"	"0.000"	""	"35"	"25"	"52"	"25"	"910"	"101.9"	"7.17"	"9699.50"	"135.17"	"18"	"25"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00565, Pf00567"	"27044"	"ENSG00000197157"	"SND1"	"hsa:27044; Q13122; Q7KZF4; Q96AG0"	"VEGFA-VEGFR2 signaling"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"1064.9"	"998.7"	"1215.4"	"1456.5"	"1088.0"	"1055.7"	"2092.9"	"2196.8"	"3224.3"	"11590.2"	"20987.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54577"	"Tyrosine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=YARS1 PE=1 SV=4"	"0.000"	""	"61"	"35"	"79"	"35"	"528"	"59.1"	"7.05"	"14931.96"	"131.35"	"31"	"31"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00579, Pf01588"	"8565"	"ENSG00000134684"	"YARS1"	"B3KWK4; D3DPQ4; hsa:8565; O43276; P54577; Q53EN1"	"Nephrotic syndrome"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"2373.4"	"2370.9"	"2739.0"	"3091.2"	"2355.4"	"2225.5"	"6127.4"	"6542.6"	"10530.3"	"29072.4"	"38071.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DMV9"	"Heat shock 70 kDa protein 1B OS=Homo sapiens OX=9606 GN=HSPA1B PE=1 SV=1"	"0.000"	""	"56"	"31"	"66"	"25"	"641"	"70.0"	"5.66"	"11573.34"	"131.15"	"24"	"28"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00012"	"3303; 3304"	"ENSG00000204388; ENSG00000212866; ENSG00000224501; ENSG00000231555; ENSG00000232804"	"HSPA1B"	"B4E3B6; hsa:3303; hsa:3304; P08107; P0DMV9; P19790; Q5JQI4; Q5SP17; Q9UQL9; Q9UQM0"	"Apoptosis modulation and signaling; Parkin-ubiquitin proteasomal system pathway; MAPK signaling pathway; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Measles virus infection; CKAP4 signaling pathway map"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Neutrophil degranulation; Attenuation phase"	"12"	"0"	"1508.9"	"1403.4"	"1699.7"	"2255.0"	"1413.8"	"1545.8"	"2632.4"	"2726.6"	"3883.5"	"9258.4"	"13147.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13435"	"Splicing factor 3B subunit 2 OS=Homo sapiens OX=9606 GN=SF3B2 PE=1 SV=2"	"0.000"	""	"29"	"27"	"64"	"27"	"895"	"100.2"	"5.67"	"13452.09"	"130.94"	"26"	"23"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02037, Pf04037, Pf04046"	"10992"	"ENSG00000087365"	"SF3B2"	"A8K485; B4DT19; hsa:10992; Q13435; Q7L4T5; Q7Z627; Q969K1; Q96CM6; Q9BWD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"3968.0"	"3284.1"	"4151.4"	"4808.6"	"3445.6"	"3684.8"	"4754.3"	"4790.9"	"5166.0"	"9646.5"	"15829.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09874"	"Poly [ADP-ribose] polymerase 1 OS=Homo sapiens OX=9606 GN=PARP1 PE=1 SV=4"	"0.000"	""	"32"	"32"	"80"	"32"	"1014"	"113.0"	"8.88"	"16265.51"	"129.74"	"32"	"29"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00533, Pf00644, Pf00645, Pf02877, Pf05406, Pf08063"	"142"	"ENSG00000143799"	"PARP1"	"B1ANJ4; hsa:142; P09874; Q8IUZ9"	"Corticotropin-releasing hormone signaling pathway; Nanoparticle triggered regulated necrosis; Fas ligand pathway and stress induction of heat shock proteins; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Breast cancer pathway; Acute viral myocarditis; Joubert syndrome; Male infertility; Base excision repair; IL-18 signaling pathway; DNA repair pathways, full network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Progeria-associated lipodystrophy; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling"	"SUMOylation of DNA damage response and repair proteins; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through MMEJ (alt-NHEJ); Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; vRNA Synthesis; POLB-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER"	"25"	"0"	"2157.8"	"2018.2"	"2349.7"	"2868.3"	"2021.2"	"2182.6"	"5180.3"	"5653.9"	"9384.5"	"20928.1"	"22659.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12906"	"Interleukin enhancer-binding factor 3 OS=Homo sapiens OX=9606 GN=ILF3 PE=1 SV=3"	"0.000"	""	"31"	"25"	"62"	"21"	"894"	"95.3"	"8.76"	"11962.78"	"127.77"	"22"	"25"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf07528"	"3609"	"ENSG00000129351"	"ILF3"	"A8K6F2; G5E9M5; hsa:3609; O43409; Q12906; Q6P1X1; Q86XY7; Q99544; Q99545; Q9BZH4; Q9BZH5; Q9NQ95; Q9NQ96; Q9NQ97; Q9NQ98; Q9NQ99; Q9NQA0; Q9NQA1; Q9NQA2; Q9NRN2; Q9NRN3; Q9NRN4; Q9UMZ9; Q9UN00; Q9UN84; Q9UNA2"	""	"Regulation of CDH11 gene transcription"	"1"	"4"	"2058.5"	"2218.0"	"2487.6"	"3709.3"	"1996.9"	"1843.1"	"3339.1"	"3641.7"	"4245.5"	"8670.5"	"11701.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4VCS5"	"Angiomotin OS=Homo sapiens OX=9606 GN=AMOT PE=1 SV=1"	"0.000"	""	"28"	"27"	"59"	"25"	"1084"	"118.0"	"7.64"	"10265.09"	"119.79"	"23"	"24"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12240"	"154796"	"ENSG00000126016"	"AMOT"	"hsa:154796; Q4VCS5; Q504X5; Q9HD27; Q9UPT1"	"VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	""	"3"	"2"	"1988.5"	"1807.4"	"2192.4"	"2668.3"	"1962.8"	"1924.6"	"3013.5"	"3080.8"	"3932.3"	"7750.1"	"11267.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08238"	"Heat shock protein HSP 90-beta OS=Homo sapiens OX=9606 GN=HSP90AB1 PE=1 SV=4"	"0.000"	""	"40"	"29"	"57"	"19"	"724"	"83.2"	"5.03"	"10024.23"	"116.23"	"23"	"27"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3326"	"ENSG00000096384"	"HSP90AB1"	"B2R5P0; hsa:3326; P08238; Q5T9W7; Q9NQW0; Q9NTK6"	"Nuclear receptors meta-pathway; NRF2 pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; Neutrophil degranulation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Aryl hydrocarbon receptor signalling; Estrogen-dependent gene expression; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; Uptake and function of diphtheria toxin"	"23"	"10"	"2270.0"	"2206.0"	"2431.2"	"3235.0"	"2009.1"	"2208.7"	"3385.5"	"3680.9"	"4375.4"	"10013.6"	"13106.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07437"	"Tubulin beta chain OS=Homo sapiens OX=9606 GN=TUBB PE=1 SV=2"	"0.000"	""	"47"	"15"	"54"	"3"	"444"	"49.6"	"4.89"	"9637.88"	"114.15"	"13"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"203068"	"ENSG00000183311; ENSG00000196230; ENSG00000224156; ENSG00000227739; ENSG00000229684; ENSG00000232421; ENSG00000232575; ENSG00000235067"	"TUBB"	"hsa:203068; P05218; P07437; Q8WUC1; Q9CY33"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Opioid receptor pathways; Alzheimer's disease"	"Potential therapeutics for SARS; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation"	"14"	"17"	"1195.8"	"1443.4"	"1351.9"	"1660.8"	"1059.0"	"1121.3"	"1839.0"	"2021.7"	"2523.2"	"5817.8"	"7554.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92841"	"Probable ATP-dependent RNA helicase DDX17 OS=Homo sapiens OX=9606 GN=DDX17 PE=1 SV=2"	"0.000"	""	"31"	"22"	"63"	"15"	"729"	"80.2"	"8.27"	"12387.70"	"113.61"	"22"	"21"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"10521"	"ENSG00000100201"	"DDX17"	"B1AHM0; H3BLZ8; hsa:10521; Q69YT1; Q6ICD6; Q92841"	"Novel intracellular components of RIG-I-like receptor pathway"	"SUMOylation of transcription cofactors"	"2"	"0"	"1669.7"	"1575.9"	"1914.9"	"2327.4"	"1547.9"	"1519.1"	"2261.4"	"2329.9"	"2731.8"	"5186.3"	"7679.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7KZ85"	"Transcription elongation factor SPT6 OS=Homo sapiens OX=9606 GN=SUPT6H PE=1 SV=2"	"0.000"	""	"23"	"30"	"49"	"30"	"1726"	"198.9"	"4.91"	"9114.36"	"109.31"	"23"	"23"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf14632, Pf14633, Pf14635, Pf14639, Pf14641, Pf17674"	"6830"	"ENSG00000109111"	"SUPT6H"	"A7E2B4; hsa:6830; Q15737; Q6GMQ4; Q7KYW9; Q7KZ85; Q7LDK4; Q8N526; Q92775; Q96AH3; Q9BTH9; Q9BTI2"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"2528.8"	"2613.6"	"2847.4"	"3750.3"	"2343.4"	"2440.6"	"3643.8"	"3716.8"	"4236.2"	"6791.3"	"8008.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68371"	"Tubulin beta-4B chain OS=Homo sapiens OX=9606 GN=TUBB4B PE=1 SV=1"	"0.000"	""	"43"	"14"	"52"	"2"	"445"	"49.8"	"4.89"	"9296.14"	"109.21"	"12"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10383"	"ENSG00000188229"	"TUBB4B"	"A2BFA2; hsa:10383; P05217; P68371"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; COPI-dependent Golgi-to-ER retrograde traffic; Recycling pathway of L1; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; Intraflagellar transport; The role of GTSE1 in G2/M progression after G2 checkpoint; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; Post-chaperonin tubulin folding pathway; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state"	"41"	"0"	"67.4"	"81.9"	"65.9"	"90.9"	"57.2"	"56.6"	"108.9"	"122.6"	"151.8"	"273.2"	"325.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15029"	"116 kDa U5 small nuclear ribonucleoprotein component OS=Homo sapiens OX=9606 GN=EFTUD2 PE=1 SV=1"	"0.000"	""	"31"	"23"	"46"	"23"	"972"	"109.4"	"5.00"	"9090.21"	"107.40"	"18"	"23"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492, Pf16004"	"9343"	"ENSG00000108883"	"EFTUD2"	"B4DK30; B4DMC0; D3DX58; hsa:9343; K7EJ81; Q15029; Q9BUR0"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"1217.6"	"1137.4"	"1458.9"	"1829.9"	"1152.9"	"1240.3"	"2055.4"	"2065.5"	"2714.5"	"8892.2"	"15807.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12956"	"X-ray repair cross-complementing protein 6 OS=Homo sapiens OX=9606 GN=XRCC6 PE=1 SV=2"	"0.000"	""	"34"	"19"	"53"	"19"	"609"	"69.8"	"6.64"	"13122.18"	"107.16"	"17"	"17"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf02735, Pf03730, Pf03731"	"2547"	"ENSG00000196419"	"XRCC6"	"B1AHC8; hsa:2547; P12956; Q6FG89; Q9UCQ2; Q9UCQ3"	"Non-homologous end joining; DNA repair pathways, full network; Primary ovarian insufficiency"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"8"	"0"	"2115.7"	"2154.6"	"2405.5"	"2921.1"	"2047.0"	"2126.4"	"3276.7"	"3357.7"	"4120.5"	"7977.1"	"10648.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35579"	"Myosin-9 OS=Homo sapiens OX=9606 GN=MYH9 PE=1 SV=4"	"0.000"	""	"16"	"22"	"40"	"19"	"1960"	"226.4"	"5.60"	"6516.20"	"107.06"	"13"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"4627"	"ENSG00000100345"	"MYH9"	"A8K6E4; hsa:4627; O60805; P35579; Q60FE2; Q86T83"	"Primary focal segmental glomerulosclerosis (FSGS); VEGFA-VEGFR2 signaling; Nephrotic syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Signaling by ALK fusions and activated point mutants; RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs; CD163 mediating an anti-inflammatory response"	"16"	"2"	"411.9"	"420.7"	"546.3"	"722.7"	"461.0"	"441.0"	"820.3"	"933.1"	"1303.8"	"5612.4"	"12770.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60506"	"Heterogeneous nuclear ribonucleoprotein Q OS=Homo sapiens OX=9606 GN=SYNCRIP PE=1 SV=2"	"0.000"	""	"41"	"24"	"57"	"14"	"623"	"69.6"	"8.59"	"9926.99"	"106.77"	"18"	"23"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10492"	"ENSG00000135316"	"SYNCRIP"	"E1P501; E1P502; hsa:10492; O60506; Q53H05; Q5TCG2; Q5TCG3; Q8IW78; Q8N599; Q96LC1; Q96LC2; Q9Y583"	""	""	"0"	"0"	"1662.0"	"1497.5"	"1983.1"	"2651.6"	"1542.2"	"1488.1"	"2526.3"	"2591.4"	"3005.2"	"6266.4"	"9022.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43390"	"Heterogeneous nuclear ribonucleoprotein R OS=Homo sapiens OX=9606 GN=HNRNPR PE=1 SV=1"	"0.000"	""	"42"	"25"	"62"	"15"	"633"	"70.9"	"8.13"	"11145.33"	"106.48"	"21"	"23"	"RNA metabolism OR transcription;other metabolic processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf18360"	"10236"	"ENSG00000125944; ENSG00000282958"	"HNRNPR"	"hsa:10236; O43390; Q2L7G6; Q5TEH1; Q9BV64; S4R3J4"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"10"	"2720.0"	"2714.4"	"3016.4"	"4351.6"	"2474.0"	"2329.9"	"4026.1"	"4132.7"	"4788.1"	"7819.3"	"10856.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00558"	"Phosphoglycerate kinase 1 OS=Homo sapiens OX=9606 GN=PGK1 PE=1 SV=3"	"0.000"	""	"52"	"19"	"43"	"19"	"417"	"44.6"	"8.10"	"7419.86"	"106.46"	"11"	"19"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00162"	"5230"	"ENSG00000102144"	"PGK1"	"A8K4W6; B7Z7A9; hsa:5230; P00558; Q5J7W1; Q6IBT6; Q8NI87"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"13"	"0"	"289.2"	"250.9"	"353.6"	"521.7"	"278.8"	"284.2"	"1314.4"	"1492.7"	"2925.1"	"13739.4"	"23183.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22102"	"Trifunctional purine biosynthetic protein adenosine-3 OS=Homo sapiens OX=9606 GN=GART PE=1 SV=1"	"0.000"	""	"32"	"28"	"48"	"28"	"1010"	"107.7"	"6.70"	"8089.97"	"105.59"	"21"	"25"	"other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00551, Pf00586, Pf01071, Pf02769, Pf02843, Pf02844"	"2618"	"ENSG00000159131; ENSG00000262473"	"GART"	"A8K945; A8KA32; D3DSF3; D3DSF4; hsa:2618; O14659; P22102; Q52M77"	"Folate metabolism; One-carbon metabolism; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"4"	"0"	"699.3"	"623.8"	"800.3"	"1003.3"	"773.7"	"1270.0"	"3849.0"	"4231.8"	"5660.7"	"14668.0"	"21104.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00571"	"ATP-dependent RNA helicase DDX3X OS=Homo sapiens OX=9606 GN=DDX3X PE=1 SV=3"	"0.000"	""	"38"	"27"	"59"	"26"	"662"	"73.2"	"7.18"	"11529.48"	"103.80"	"23"	"24"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1654"	"ENSG00000215301"	"DDX3X"	"A8K538; B4E3E8; hsa:1654; O00571; O15536"	"Novel intracellular components of RIG-I-like receptor pathway; Hepatitis B infection"	"Neutrophil degranulation"	"3"	"1"	"2494.4"	"2154.9"	"2913.2"	"4127.4"	"2286.1"	"2177.1"	"3893.1"	"3901.7"	"4705.5"	"7929.4"	"9530.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13010"	"X-ray repair cross-complementing protein 5 OS=Homo sapiens OX=9606 GN=XRCC5 PE=1 SV=3"	"0.000"	""	"34"	"23"	"54"	"23"	"732"	"82.7"	"5.81"	"10211.44"	"103.10"	"19"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02735, Pf03730, Pf03731, Pf08785"	"7520"	"ENSG00000079246"	"XRCC5"	"A8K3X5; hsa:7520; P13010; Q0Z7V0; Q4VBQ5; Q53HH7; Q7M4N0; Q9UCQ0; Q9UCQ1"	"Non-homologous end joining; Male infertility; DNA repair pathways, full network; p53 transcriptional gene network"	"Neutrophil degranulation; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); 2-LTR circle formation; IRF3-mediated induction of type I IFN"	"9"	"0"	"1705.3"	"1571.0"	"1923.2"	"2434.4"	"1525.4"	"1657.1"	"2504.9"	"2630.1"	"3295.5"	"7118.3"	"10592.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB71"	"Calcyclin-binding protein OS=Homo sapiens OX=9606 GN=CACYBP PE=1 SV=2"	"0.000"	""	"52"	"19"	"48"	"19"	"228"	"26.2"	"8.25"	"10660.93"	"102.84"	"17"	"16"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04969, Pf05002, Pf09032"	"27101"	"ENSG00000116161"	"CACYBP"	"B2ZWH2; B3KSF1; hsa:27101; O60666; Q5R370; Q5R371; Q9HB71"	"Gastric cancer network 2"	""	"1"	"0"	"976.0"	"970.5"	"993.2"	"1137.7"	"1006.8"	"1230.4"	"4712.0"	"5395.5"	"6821.4"	"14541.2"	"21876.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ80"	"Proliferation-associated protein 2G4 OS=Homo sapiens OX=9606 GN=PA2G4 PE=1 SV=3"	"0.000"	""	"47"	"18"	"56"	"18"	"394"	"43.8"	"6.55"	"10772.56"	"102.45"	"17"	"18"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00557"	"5036"	"ENSG00000170515"	"PA2G4"	"hsa:5036; O43846; Q9UM59; Q9UQ80"	""	"Neutrophil degranulation"	"1"	"0"	"1064.5"	"971.6"	"1199.8"	"1509.9"	"1019.4"	"1054.0"	"3329.5"	"3587.6"	"6468.4"	"11702.0"	"10545.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07814"	"Bifunctional glutamate/proline--tRNA ligase OS=Homo sapiens OX=9606 GN=EPRS1 PE=1 SV=5"	"0.000"	""	"26"	"31"	"56"	"30"	"1512"	"170.5"	"7.33"	"11518.75"	"101.58"	"24"	"25"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf00587, Pf00749, Pf03129, Pf03950, Pf09180"	"2058"	"ENSG00000136628"	"EPRS1"	"A0AVA9; B9EGH3; hsa:2058; P07814; Q05BP6; Q05DF8; Q5DSM1; Q5H9S5; Q6PD57; Q86X73"	"Parkinson's disease pathway; VEGFA-VEGFR2 signaling; Amino acid metabolism"	"tRNA modification in the nucleus and cytosol; Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"6"	"1"	"2220.3"	"2015.0"	"2323.8"	"2768.6"	"2001.0"	"2005.2"	"3537.0"	"3646.0"	"5059.3"	"14598.5"	"20554.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93009"	"Ubiquitin carboxyl-terminal hydrolase 7 OS=Homo sapiens OX=9606 GN=USP7 PE=1 SV=2"	"0.000"	""	"24"	"18"	"43"	"18"	"1102"	"128.2"	"5.55"	"8637.47"	"100.51"	"15"	"18"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00443, Pf00917, Pf12436, Pf14533"	"7874"	"ENSG00000187555"	"USP7"	"A6NMY8; B7Z815; H0Y3G8; hsa:7874; Q93009"	"Nucleotide excision repair in xeroderma pigmentosum ; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Ub-specific processing proteases; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Regulation of TP53 Degradation; Formation of TC-NER Pre-Incision Complex; Regulation of PTEN localization"	"10"	"0"	"884.6"	"979.7"	"1040.5"	"1301.6"	"882.2"	"887.3"	"1674.2"	"1747.3"	"2372.2"	"7200.5"	"11994.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78527"	"DNA-dependent protein kinase catalytic subunit OS=Homo sapiens OX=9606 GN=PRKDC PE=1 SV=3"	"0.000"	""	"8"	"26"	"55"	"26"	"4128"	"468.8"	"7.12"	"11936.90"	"99.79"	"25"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00454, Pf02259, Pf02260, Pf08163, Pf19704, Pf20502"	"5591"	"ENSG00000253729"	"PRKDC"	"hsa:5591; P78527; P78528; Q13327; Q13337; Q14175; Q59H99; Q7Z611; Q96SE6; Q9UME3"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Fas ligand pathway and stress induction of heat shock proteins; Pathways affected in adenoid cystic carcinoma; ATM signaling in development and disease ; Non-homologous end joining; Osteoblast differentiation and related diseases; DNA repair pathways, full network; DNA damage response"	"E3 ubiquitin ligases ubiquitinate target proteins; Cytosolic sensors of pathogen-associated DNA ; Nonhomologous End-Joining (NHEJ); IRF3-mediated induction of type I IFN"	"14"	"0"	"1156.9"	"1112.0"	"1363.4"	"1626.8"	"1111.0"	"1165.0"	"2202.6"	"2318.2"	"3640.9"	"8521.6"	"11110.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04264"	"Keratin, type II cytoskeletal 1 OS=Homo sapiens OX=9606 GN=KRT1 PE=1 SV=6"	"0.000"	""	"31"	"19"	"52"	"16"	"644"	"66.0"	"8.12"	"8973.94"	"97.90"	"17"	"19"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038, Pf16208, Pf16210"	"3848"	"ENSG00000167768"	"KRT1"	"B2RA01; hsa:3848; P04264; P85925; P86104; Q14720; Q6GSJ0; Q9H298"	"Corticotropin-releasing hormone signaling pathway"	"Formation of the cornified envelope; Neutrophil degranulation"	"4"	"3"	"2118.1"	"2650.6"	"11689.0"	"1493.8"	"522.7"	"1689.4"	"6589.1"	"4239.5"	"3639.1"	"6375.8"	"6751.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06733"	"Alpha-enolase OS=Homo sapiens OX=9606 GN=ENO1 PE=1 SV=2"	"0.000"	""	"40"	"16"	"40"	"16"	"434"	"47.1"	"7.39"	"6640.02"	"97.00"	"11"	"16"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00113, Pf03952"	"2023"	"ENSG00000074800"	"ENO1"	"B2RD59; hsa:2023; P06733; P22712; Q16704; Q4TUS4; Q53FT9; Q53HR3; Q658M5; Q6GMP2; Q71V37; Q7Z3V6; Q8WU71; Q96GV1; Q9BT62; Q9UCH6; Q9UM55"	"Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; IL-18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis; Gluconeogenesis; Manipulation of host energy metabolism"	"9"	"0"	"647.2"	"538.0"	"928.1"	"1347.9"	"662.2"	"620.4"	"1901.0"	"2078.6"	"3457.6"	"11656.9"	"19347.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09651"	"Heterogeneous nuclear ribonucleoprotein A1 OS=Homo sapiens OX=9606 GN=HNRNPA1 PE=1 SV=5"	"0.000"	""	"41"	"18"	"47"	"15"	"372"	"38.7"	"9.13"	"8390.21"	"96.96"	"11"	"15"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11627"	"3178"	"ENSG00000135486"	"HNRNPA1"	"A8K4Z8; hsa:3178; P09651; Q3MIB7; Q6PJZ7"	"mRNA processing"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; SARS-CoV-1-host interactions; SARS-CoV-1 modulates host translation machinery"	"6"	"0"	"1757.1"	"2002.1"	"1831.8"	"2248.1"	"1564.5"	"1513.6"	"2129.3"	"2223.1"	"2347.4"	"3714.0"	"5089.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99459"	"Cell division cycle 5-like protein OS=Homo sapiens OX=9606 GN=CDC5L PE=1 SV=2"	"0.000"	""	"36"	"23"	"47"	"23"	"802"	"92.2"	"8.18"	"8982.07"	"95.30"	"20"	"19"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11831, Pf13921"	"988"	"ENSG00000096401"	"CDC5L"	"hsa:988; Q76N46; Q99459; Q99974"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1365.1"	"1233.5"	"1546.4"	"1860.1"	"1264.1"	"1308.2"	"3096.0"	"3255.5"	"4838.2"	"14038.6"	"17695.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17844"	"Probable ATP-dependent RNA helicase DDX5 OS=Homo sapiens OX=9606 GN=DDX5 PE=1 SV=1"	"0.000"	""	"41"	"24"	"53"	"17"	"614"	"69.1"	"8.92"	"9838.25"	"94.85"	"22"	"22"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08061"	"1655"	"ENSG00000108654"	"DDX5"	"B4DLW8; B5BU21; D3DU32; E7ETL9; hsa:1655; O75681; P17844; Q53Y61"	"Ciliary landscape"	"Estrogen-dependent gene expression; SUMOylation of transcription cofactors; mRNA Splicing - Major Pathway; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"6"	"6"	"3379.6"	"3255.1"	"3815.4"	"4779.3"	"3006.6"	"3231.5"	"4477.6"	"4465.8"	"5076.7"	"9478.8"	"14050.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25205"	"DNA replication licensing factor MCM3 OS=Homo sapiens OX=9606 GN=MCM3 PE=1 SV=3"	"0.000"	""	"34"	"22"	"39"	"22"	"808"	"90.9"	"5.77"	"6374.54"	"94.83"	"15"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4172"	"ENSG00000112118"	"MCM3"	"B4DWW4; hsa:4172; P25205; Q92660; Q9BTR3; Q9NUE7"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"1615.0"	"1603.3"	"1736.4"	"2349.4"	"1453.8"	"1498.2"	"2470.8"	"2567.2"	"3146.6"	"7499.6"	"11176.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05455"	"Lupus La protein OS=Homo sapiens OX=9606 GN=SSB PE=1 SV=2"	"0.000"	""	"47"	"22"	"52"	"22"	"408"	"46.8"	"7.12"	"12131.62"	"94.54"	"22"	"19"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"6741"	"ENSG00000138385"	"SSB"	"hsa:6741; P05455; Q15367; Q53XJ4"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Termination"	"2"	"0"	"3673.3"	"3478.2"	"3726.7"	"4587.0"	"3388.7"	"3611.0"	"5475.5"	"5694.0"	"6963.1"	"11849.5"	"15854.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50990"	"T-complex protein 1 subunit theta OS=Homo sapiens OX=9606 GN=CCT8 PE=1 SV=4"	"0.000"	""	"41"	"20"	"38"	"20"	"548"	"59.6"	"5.60"	"6422.65"	"94.42"	"13"	"19"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10694"	"ENSG00000156261"	"CCT8"	"A6NN54; B4DEM7; B4DQH4; hsa:10694; P50990; Q4VBP8"	"16p11.2 proximal deletion syndrome"	"Association of TriC/CCT with target proteins during biosynthesis; Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"581.1"	"530.2"	"738.7"	"877.2"	"558.0"	"616.5"	"1251.3"	"1332.0"	"1872.5"	"9998.0"	"20624.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42285"	"Exosome RNA helicase MTR4 OS=Homo sapiens OX=9606 GN=MTREX PE=1 SV=3"	"0.000"	""	"22"	"21"	"44"	"21"	"1042"	"117.7"	"6.52"	"7451.84"	"94.17"	"16"	"20"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08148, Pf13234"	"23517"	"ENSG00000039123"	"MTREX"	"hsa:23517; P42285; Q2M386; Q6MZZ8; Q6P170; Q8N5R0; Q8TAG2"	""	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"939.6"	"826.3"	"1155.7"	"1428.2"	"952.5"	"968.3"	"1968.1"	"2117.4"	"3352.7"	"9332.7"	"13535.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92945"	"Far upstream element-binding protein 2 OS=Homo sapiens OX=9606 GN=KHSRP PE=1 SV=4"	"0.000"	""	"31"	"18"	"38"	"15"	"711"	"73.1"	"7.30"	"6258.95"	"94.13"	"15"	"16"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf09005"	"8570"	"ENSG00000088247"	"KHSRP"	"hsa:8570; O00301; Q59EZ9; Q5U4P6; Q92945; Q9UNT5; Q9UQH5"	"Pre-implantation embryo"	"ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA"	"3"	"3"	"2009.9"	"1902.2"	"2120.7"	"2673.3"	"1872.4"	"2025.6"	"2879.3"	"2863.3"	"3256.7"	"5497.5"	"7851.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15924"	"Desmoplakin OS=Homo sapiens OX=9606 GN=DSP PE=1 SV=3"	"0.000"	""	"9"	"25"	"52"	"25"	"2871"	"331.6"	"6.81"	"9037.24"	"93.86"	"23"	"24"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00681, Pf17902, Pf18373"	"1832"	"ENSG00000096696"	"DSP"	"B2RTT2; D7RX09; hsa:1832; O75993; P15924; Q14189; Q9UHN4"	"Arrhythmogenic right ventricular cardiomyopathy; Lung fibrosis; Epithelial to mesenchymal transition in colorectal cancer"	"Formation of the cornified envelope; Neutrophil degranulation; RND3 GTPase cycle; RND1 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"9"	"0"	"2240.5"	"2162.3"	"3744.6"	"2881.7"	"1900.2"	"2123.3"	"3322.4"	"3383.3"	"3883.7"	"8520.0"	"12148.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15393"	"Splicing factor 3B subunit 3 OS=Homo sapiens OX=9606 GN=SF3B3 PE=1 SV=4"	"0.000"	""	"20"	"19"	"42"	"19"	"1217"	"135.5"	"5.26"	"7759.02"	"93.68"	"18"	"19"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"23450"	"ENSG00000189091"	"SF3B3"	"hsa:23450; Q15393; Q6NTI8; Q96GC0; Q9BPY2; Q9UFX7; Q9UJ29"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"1207.2"	"1074.0"	"1357.8"	"1893.5"	"1195.3"	"1189.4"	"2223.1"	"2227.7"	"2948.9"	"8536.0"	"15321.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14103"	"Heterogeneous nuclear ribonucleoprotein D0 OS=Homo sapiens OX=9606 GN=HNRNPD PE=1 SV=1"	"0.000"	""	"38"	"17"	"56"	"15"	"355"	"38.4"	"7.81"	"12270.15"	"93.17"	"16"	"16"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3184"	"ENSG00000138668"	"HNRNPD"	"A8K9J2; hsa:3184; P07029; Q01858; Q14100; Q14101; Q14102; Q14103; Q4W5A1; Q9UCE8; Q9UCE9"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"3"	"3175.8"	"3521.4"	"3627.9"	"4581.7"	"3108.1"	"2409.4"	"4537.1"	"4681.4"	"4927.2"	"7881.4"	"10571.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96N67"	"Dedicator of cytokinesis protein 7 OS=Homo sapiens OX=9606 GN=DOCK7 PE=1 SV=4"	"0.000"	""	"17"	"28"	"49"	"28"	"2140"	"242.4"	"6.80"	"8408.33"	"90.80"	"23"	"24"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"85440"	"ENSG00000116641"	"DOCK7"	"hsa:85440; Q00M63; Q2PPY7; Q45RE8; Q45RE9; Q5T1B9; Q5T1C0; Q6ZV32; Q8TB82; Q96N67; Q96NG6; Q96NI0; Q9C092"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production; MET activates RAP1 and RAC1"	"4"	"0"	"1257.9"	"1150.9"	"1464.8"	"1696.2"	"1271.0"	"1465.3"	"2930.1"	"3273.0"	"4639.1"	"10781.4"	"13001.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68363"	"Tubulin alpha-1B chain OS=Homo sapiens OX=9606 GN=TUBA1B PE=1 SV=1"	"0.000"	""	"44"	"16"	"40"	"2"	"451"	"50.1"	"5.06"	"6765.46"	"90.60"	"12"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00091, Pf03953"	"10376"	"ENSG00000123416"	"TUBA1B"	"hsa:10376; P04687; P05209; P68363; Q27I68; Q8WU19"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Allograft rejection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"HCMV Early Events; RHO GTPases Activate Formins; Intraflagellar transport; Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Formation of tubulin folding intermediates by CCT/TriC; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Hedgehog 'off' state; RHOH GTPase cycle"	"35"	"14"	"1414.6"	"1663.5"	"1559.3"	"1819.8"	"1291.6"	"1332.6"	"2252.5"	"2538.1"	"3218.4"	"8100.4"	"11407.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62316"	"Small nuclear ribonucleoprotein Sm D2 OS=Homo sapiens OX=9606 GN=SNRPD2 PE=1 SV=1"	"0.000"	""	"69"	"11"	"60"	"11"	"118"	"13.5"	"9.91"	"13997.55"	"90.10"	"10"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf01423"	"6633"	"ENSG00000125743"	"SNRPD2"	"A8K797; hsa:6633; J3KPM5; P43330; P62316"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"2404.4"	"1808.2"	"2817.8"	"3569.4"	"2126.5"	"2096.9"	"2764.0"	"2782.8"	"2887.4"	"4890.2"	"7971.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43290"	"U4/U6.U5 tri-snRNP-associated protein 1 OS=Homo sapiens OX=9606 GN=SART1 PE=1 SV=1"	"0.000"	""	"34"	"22"	"45"	"22"	"800"	"90.2"	"6.13"	"8767.85"	"90.09"	"20"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf03343, Pf19252"	"9092"	"ENSG00000175467"	"SART1"	"A6NDN1; hsa:9092; O43290; Q53GB5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"2084.1"	"1858.1"	"2141.3"	"2514.3"	"1888.3"	"1838.0"	"2630.1"	"2690.0"	"2975.6"	"5462.6"	"7626.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10809"	"60 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPD1 PE=1 SV=2"	"0.000"	""	"33"	"20"	"49"	"20"	"573"	"61.0"	"5.87"	"9929.22"	"89.63"	"18"	"20"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00118"	"3329"	"ENSG00000144381"	"HSPD1"	"B2R5M6; B7Z712; hsa:3329; P10809; Q38L19; Q9UCR6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; 8p23.1 copy number variation syndrome; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Mitochondrial protein import; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"5"	"0"	"1611.6"	"1390.8"	"1864.1"	"2199.5"	"1416.9"	"1584.3"	"2630.2"	"2640.3"	"3284.9"	"6684.8"	"11898.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92878"	"DNA repair protein RAD50 OS=Homo sapiens OX=9606 GN=RAD50 PE=1 SV=1"	"0.000"	""	"19"	"21"	"40"	"21"	"1312"	"153.8"	"6.89"	"6281.37"	"89.30"	"17"	"21"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04423, Pf13476, Pf13558"	"10111"	"ENSG00000113522"	"RAD50"	"B9EGF5; hsa:10111; O43254; Q6GMT7; Q6P5X3; Q92878; Q9UP86"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; DNA damage response"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Resolution of D-loop Structures through Holliday Junction Intermediates; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"29"	"0"	"1077.9"	"953.4"	"1389.0"	"1532.1"	"1090.6"	"1084.5"	"2197.7"	"2264.0"	"3165.2"	"9385.1"	"15166.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46013"	"Proliferation marker protein Ki-67 OS=Homo sapiens OX=9606 GN=MKI67 PE=1 SV=2"	"0.000"	""	"13"	"29"	"53"	"28"	"3256"	"358.5"	"9.45"	"10865.44"	"89.09"	"28"	"23"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08065, Pf15276"	"4288"	"ENSG00000148773"	"MKI67"	"hsa:4288; P46013; Q5VWH2"	"Primary focal segmental glomerulosclerosis (FSGS)"	""	"1"	"1"	"3225.7"	"3212.4"	"3273.9"	"3806.1"	"3301.6"	"2993.8"	"4206.2"	"4494.8"	"5216.5"	"7956.8"	"8633.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35221"	"Catenin alpha-1 OS=Homo sapiens OX=9606 GN=CTNNA1 PE=1 SV=1"	"0.000"	""	"30"	"22"	"42"	"22"	"906"	"100.0"	"6.29"	"7691.29"	"88.99"	"19"	"20"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"1495"	"ENSG00000044115"	"CTNNA1"	"hsa:1495; P35221; Q12795; Q8N1C0"	"Arrhythmogenic right ventricular cardiomyopathy; Apoptosis-related network due to altered Notch3 in ovarian cancer; VEGFA-VEGFR2 signaling; White fat cell differentiation; Endometrial cancer; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Pleural mesothelioma"	"RHO GTPases activate IQGAPs; Myogenesis; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"15"	"0"	"587.8"	"501.5"	"748.3"	"1014.9"	"589.0"	"622.4"	"1562.5"	"1668.2"	"3113.1"	"9230.9"	"11249.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15459"	"Splicing factor 3A subunit 1 OS=Homo sapiens OX=9606 GN=SF3A1 PE=1 SV=1"	"0.000"	""	"28"	"19"	"40"	"19"	"793"	"88.8"	"5.22"	"8211.91"	"88.56"	"17"	"19"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00240, Pf01805, Pf12230"	"10291"	"ENSG00000099995"	"SF3A1"	"E9PAW1; hsa:10291; Q15459"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"866.9"	"896.6"	"924.3"	"1262.7"	"819.3"	"871.8"	"1614.9"	"1668.9"	"2560.7"	"8474.6"	"12320.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22234"	"Multifunctional protein ADE2 OS=Homo sapiens OX=9606 GN=PAICS PE=1 SV=3"	"0.000"	""	"37"	"16"	"42"	"16"	"425"	"47.0"	"7.23"	"8531.18"	"88.37"	"13"	"14"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00731, Pf01259"	"10606"	"ENSG00000128050"	"PAICS"	"E9PDH9; hsa:10606; P22234; Q68CQ5"	"Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"2"	"0"	"836.9"	"792.1"	"927.5"	"1132.6"	"798.7"	"728.0"	"1570.5"	"1620.9"	"2342.9"	"10173.7"	"15093.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60891"	"Ribose-phosphate pyrophosphokinase 1 OS=Homo sapiens OX=9606 GN=PRPS1 PE=1 SV=2"	"0.000"	""	"54"	"16"	"42"	"9"	"318"	"34.8"	"6.98"	"8472.21"	"87.61"	"14"	"15"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5631"	"ENSG00000147224"	"PRPS1"	"B1ALA8; B2R6T7; B4DNL6; D3DUX6; hsa:5631; P09329; P60891"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"10"	"1154.6"	"1632.2"	"1321.4"	"1443.7"	"1037.3"	"1172.8"	"2230.8"	"2406.8"	"3309.3"	"8620.6"	"10664.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06748"	"Nucleophosmin OS=Homo sapiens OX=9606 GN=NPM1 PE=1 SV=2"	"0.000"	""	"54"	"19"	"46"	"19"	"294"	"32.6"	"4.78"	"9680.35"	"87.38"	"16"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03066, Pf16276"	"4869"	"ENSG00000181163"	"NPM1"	"A8K3N7; B5BU00; D3DQL6; hsa:4869; P06748; P08693; Q12826; Q13440; Q13441; Q14115; Q5EU94; Q5EU95; Q5EU96; Q5EU97; Q5EU98; Q5EU99; Q6V962; Q8WTW5; Q96AT6; Q96DC4; Q96EA5; Q9BYG9; Q9UDJ7"	""	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Nuclear import of Rev protein; Deposition of new CENPA-containing nucleosomes at the centromere; SUMOylation of transcription cofactors; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation; SARS-CoV-1-host interactions"	"9"	"0"	"6540.4"	"6256.1"	"6099.0"	"6516.1"	"5318.3"	"5427.3"	"7756.0"	"7709.1"	"8222.2"	"11515.5"	"12742.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07910"	"Heterogeneous nuclear ribonucleoproteins C1/C2 OS=Homo sapiens OX=9606 GN=HNRNPC PE=1 SV=4"	"0.000"	""	"30"	"14"	"47"	"14"	"306"	"33.7"	"5.08"	"11263.52"	"86.83"	"14"	"13"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"3183"	"ENSG00000092199"	"HNRNPC"	"D3DS19; D3DS22; hsa:3183; P07910; P22628; Q53EX2; Q59FD3; Q5FWE8; Q86SF8; Q86U45; Q96HK7; Q96HM4; Q96IY5; Q9BTS3"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA; SUMOylation of RNA binding proteins; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"6"	"0"	"3240.5"	"3914.5"	"3652.7"	"4228.9"	"2962.6"	"3069.3"	"4214.1"	"4250.2"	"4514.6"	"8237.5"	"11841.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12874"	"Splicing factor 3A subunit 3 OS=Homo sapiens OX=9606 GN=SF3A3 PE=1 SV=1"	"0.000"	""	"35"	"17"	"42"	"17"	"501"	"58.8"	"5.38"	"8315.23"	"86.71"	"13"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11931, Pf12108, Pf13297, Pf16837"	"10946"	"ENSG00000183431"	"SF3A3"	"D3DPT5; hsa:10946; Q12874; Q15460; Q5VT87"	"Exercise-induced circadian regulation; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"0"	"1413.5"	"1308.2"	"1378.0"	"1848.0"	"1230.4"	"1295.1"	"2355.4"	"2566.7"	"3552.4"	"12618.9"	"17306.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40939"	"Trifunctional enzyme subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=HADHA PE=1 SV=2"	"0.000"	""	"31"	"19"	"38"	"19"	"763"	"82.9"	"9.04"	"7066.32"	"86.52"	"14"	"18"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"3030"	"ENSG00000084754"	"HADHA"	"B2R7L4; B4DYP2; hsa:3030; P40939; Q16679; Q53T69; Q53TA2; Q96GT7; Q9UQC5"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Mitochondrial fatty acid oxidation disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"13"	"0"	"959.0"	"967.6"	"1171.5"	"1503.9"	"920.8"	"963.6"	"1781.9"	"1875.0"	"2602.3"	"8146.6"	"13202.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04075"	"Fructose-bisphosphate aldolase A OS=Homo sapiens OX=9606 GN=ALDOA PE=1 SV=2"	"0.000"	""	"47"	"21"	"47"	"21"	"364"	"39.4"	"8.09"	"10435.90"	"86.35"	"19"	"17"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00274"	"226"	"ENSG00000149925"	"ALDOA"	"B4DXI7; hsa:226; P04075; Q6FH76; Q6FI10; Q96B15; Q9BWD9; Q9UCN2"	"VEGFA-VEGFR2 signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; 16p11.2 proximal deletion syndrome; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Glycolysis; Gluconeogenesis; Neutrophil degranulation; Platelet degranulation"	"11"	"0"	"2815.2"	"2625.1"	"2869.1"	"3704.3"	"2521.4"	"2462.9"	"4066.8"	"4151.0"	"4390.0"	"8987.6"	"14111.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17987"	"T-complex protein 1 subunit alpha OS=Homo sapiens OX=9606 GN=TCP1 PE=1 SV=1"	"0.000"	""	"38"	"15"	"36"	"15"	"556"	"60.3"	"6.11"	"6759.79"	"85.60"	"12"	"15"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00118"	"6950"	"ENSG00000120438"	"TCP1"	"E1P5B2; hsa:6950; P17987; Q15556; Q5TCM3"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"8"	"0"	"469.5"	"408.4"	"605.6"	"606.3"	"400.7"	"442.0"	"950.8"	"993.2"	"1616.5"	"6865.8"	"12718.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11021"	"Endoplasmic reticulum chaperone BiP OS=Homo sapiens OX=9606 GN=HSPA5 PE=1 SV=2"	"0.000"	""	"37"	"24"	"49"	"22"	"654"	"72.3"	"5.16"	"9594.52"	"85.03"	"21"	"22"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00012"	"3309"	"ENSG00000044574"	"HSPA5"	"B0QZ61; hsa:3309; P11021; Q2EF78; Q9NPF1; Q9UK02"	"Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Photodynamic therapy-induced unfolded protein response; Prion disease pathway; Unfolded protein response; Orexin receptor pathway"	"Regulation of HSF1-mediated heat shock response; Platelet degranulation ; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; ATF6B (ATF6-beta) activates chaperones; IRE1alpha activates chaperones; PERK regulates gene expression; ATF6 (ATF6-alpha) activates chaperone genes"	"14"	"0"	"1760.2"	"1508.1"	"2251.6"	"2736.6"	"1541.8"	"1686.3"	"2925.1"	"3104.0"	"4099.6"	"10769.9"	"15862.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40926"	"Malate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=MDH2 PE=1 SV=3"	"0.000"	""	"61"	"17"	"49"	"17"	"338"	"35.5"	"8.68"	"8897.85"	"84.37"	"16"	"15"	"other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"4191"	"ENSG00000146701"	"MDH2"	"A8K414; B2RE78; B4DE44; E9PDB2; hsa:4191; O43682; P40926"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"Gluconeogenesis; Citric acid cycle (TCA cycle)"	"8"	"0"	"2536.9"	"2457.7"	"2500.4"	"2497.0"	"2225.9"	"2262.4"	"3965.4"	"3949.1"	"5633.6"	"13738.9"	"15566.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01081"	"Splicing factor U2AF 35 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF1 PE=1 SV=3"	"0.000"	""	"48"	"9"	"27"	"9"	"240"	"27.9"	"8.81"	"4154.17"	"84.35"	"4"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00642"	"102724594; 7307"	"ENSG00000160201"	"U2AF1"	"hsa:102724594; hsa:7307; Q01081; Q701P4; Q71RF1"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"341.5"	"343.2"	"370.3"	"507.9"	"304.8"	"278.2"	"782.0"	"858.0"	"1542.3"	"4081.0"	"5220.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2J5"	"Leucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=LARS1 PE=1 SV=2"	"0.000"	""	"21"	"18"	"39"	"18"	"1176"	"134.4"	"7.30"	"7698.58"	"83.32"	"15"	"16"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00133, Pf08264"	"51520"	"ENSG00000133706"	"LARS1"	"A2RRR4; A7E266; B4DJ10; hsa:51520; Q2TU79; Q9NSE1; Q9P2J5"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"755.8"	"682.9"	"821.0"	"924.4"	"696.0"	"725.5"	"1295.8"	"1401.7"	"1982.7"	"6328.0"	"9367.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14868"	"Aspartate--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=DARS1 PE=1 SV=2"	"0.000"	""	"41"	"18"	"42"	"18"	"501"	"57.1"	"6.55"	"8557.26"	"83.20"	"17"	"17"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00152, Pf01336"	"1615"	"ENSG00000115866"	"DARS1"	"A8K3J2; D3DP77; hsa:1615; P14868; Q2TNI3; Q32Q69; Q53HV4; Q53YC5; Q68CR9; Q9BW52"	"Alanine and aspartate metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"573.4"	"559.5"	"624.9"	"763.1"	"569.7"	"604.8"	"1717.5"	"1901.7"	"3248.5"	"10744.6"	"14527.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47897"	"Glutamine--tRNA ligase OS=Homo sapiens OX=9606 GN=QARS1 PE=1 SV=1"	"0.000"	""	"28"	"20"	"46"	"19"	"775"	"87.7"	"7.15"	"8784.76"	"82.61"	"18"	"20"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00749, Pf03950, Pf04557, Pf04558"	"5859"	"ENSG00000172053"	"QARS1"	"B4DWJ2; hsa:5859; P47897"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"781.2"	"681.1"	"790.4"	"952.7"	"697.6"	"738.8"	"1192.0"	"1287.5"	"1803.4"	"5577.6"	"8702.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12955"	"Ankyrin-3 OS=Homo sapiens OX=9606 GN=ANK3 PE=1 SV=3"	"0.000"	""	"6"	"23"	"42"	"20"	"4377"	"480.1"	"6.49"	"7705.30"	"82.28"	"20"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00531, Pf00791, Pf12796, Pf17809"	"288"	"ENSG00000151150"	"ANK3"	"B1AQT2; B4DIL1; E9PE32; hsa:288; Q12955; Q13484; Q5CZH9; Q5VXD5; Q7Z3G4; Q9H0P5"	"Splicing factor NOVA regulated synaptic proteins"	"COPI-mediated anterograde transport; Interaction between L1 and Ankyrins"	"3"	"3"	"1685.7"	"1516.0"	"1657.3"	"2007.3"	"1428.1"	"1500.0"	"2494.9"	"2612.9"	"3394.8"	"6104.9"	"7470.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78371"	"T-complex protein 1 subunit beta OS=Homo sapiens OX=9606 GN=CCT2 PE=1 SV=4"	"0.000"	""	"35"	"14"	"30"	"14"	"535"	"57.5"	"6.46"	"7199.93"	"81.37"	"8"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00118"	"10576"	"ENSG00000166226"	"CCT2"	"A8K402; B5BTY7; B7Z243; B7Z7K4; B7ZAT2; hsa:10576; P78371; Q14D36; Q6IAT3"	"16p11.2 proximal deletion syndrome"	"Neutrophil degranulation; Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle; Folding of actin by CCT/TriC"	"10"	"0"	"309.5"	"226.3"	"393.6"	"463.3"	"296.1"	"329.7"	"538.0"	"552.5"	"831.2"	"3963.0"	"8545.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14979"	"Heterogeneous nuclear ribonucleoprotein D-like OS=Homo sapiens OX=9606 GN=HNRNPDL PE=1 SV=3"	"0.000"	""	"29"	"16"	"44"	"14"	"420"	"46.4"	"9.57"	"11362.30"	"81.24"	"16"	"14"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00076"	"9987"	"ENSG00000152795"	"HNRNPDL"	"hsa:9987; O14979; Q6SPF2; Q7KZ74; Q7KZ75; Q96IM0; Q96S43"	""	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"1"	"0"	"2164.2"	"2128.0"	"2193.8"	"2699.7"	"1976.9"	"1603.9"	"2784.0"	"2753.3"	"2873.7"	"4189.6"	"6001.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57740"	"Nuclear pore complex protein Nup107 OS=Homo sapiens OX=9606 GN=NUP107 PE=1 SV=1"	"0.000"	""	"19"	"15"	"36"	"15"	"925"	"106.3"	"5.43"	"6649.67"	"80.61"	"13"	"15"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04121"	"57122"	"ENSG00000111581"	"NUP107"	"B4DZ67; hsa:57122; P57740; Q6PJE1"	"Gastric cancer network 1; Primary ovarian insufficiency"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Vpr-mediated nuclear import of PICs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; RHO GTPases Activate Formins; Regulation of HSF1-mediated heat shock response; SUMOylation of chromatin organization proteins; HCMV Late Events; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"37"	"0"	"1230.0"	"1165.1"	"1371.9"	"1534.9"	"1275.0"	"1176.4"	"1787.3"	"1846.0"	"2120.0"	"3843.6"	"5051.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23284"	"Peptidyl-prolyl cis-trans isomerase B OS=Homo sapiens OX=9606 GN=PPIB PE=1 SV=2"	"0.000"	""	"56"	"16"	"45"	"16"	"216"	"23.7"	"9.41"	"8989.64"	"80.49"	"15"	"16"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"5479"	"ENSG00000166794"	"PPIB"	"A8K534; hsa:5479; P23284; Q6IBH5; Q9BVK5"	"Prolactin signaling pathway; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes; SARS-CoV-1 activates/modulates innate immune responses"	"4"	"0"	"1609.9"	"1449.7"	"2013.0"	"2226.5"	"2042.6"	"2909.0"	"6581.0"	"7163.4"	"11059.7"	"10856.2"	"7606.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71U36"	"Tubulin alpha-1A chain OS=Homo sapiens OX=9606 GN=TUBA1A PE=1 SV=1"	"0.000"	""	"41"	"15"	"35"	"1"	"451"	"50.1"	"5.06"	"5969.91"	"80.39"	"11"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7846"	"ENSG00000167552"	"TUBA1A"	"A8K0B8; G3V1U9; hsa:7846; P04687; P05209; Q71U36"	"Alzheimer's disease and miRNA effects; Pathogenic Escherichia coli infection; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Recycling pathway of L1; MHC class II antigen presentation; Recruitment of mitotic centrosome proteins and complexes; Formation of tubulin folding intermediates by CCT/TriC; Prefoldin mediated transfer of substrate  to CCT/TriC; HCMV Early Events; Intraflagellar transport; COPI-dependent Golgi-to-ER retrograde traffic; The role of GTSE1 in G2/M progression after G2 checkpoint; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane; Gap junction assembly; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Post-chaperonin tubulin folding pathway; RHO GTPases activate IQGAPs; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Carboxyterminal post-translational modifications of tubulin; Assembly and cell surface presentation of NMDA receptors; Activation of AMPK downstream of NMDARs; Aggrephagy; Sealing of the nuclear envelope (NE) by ESCRT-III; Kinesins; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Hedgehog 'off' state"	"41"	"0"	"44.7"	"32.2"	"64.1"	"85.9"	"54.5"	"31.2"	"88.8"	"89.4"	"140.6"	"328.7"	"549.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43776"	"Asparagine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=NARS1 PE=1 SV=1"	"0.000"	""	"34"	"19"	"42"	"19"	"548"	"62.9"	"6.25"	"9607.87"	"80.28"	"17"	"15"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"4677"	"ENSG00000134440"	"NARS1"	"B4DG16; hsa:4677; O43776; Q53GU6"	"Photodynamic therapy-induced unfolded protein response"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"1819.1"	"1842.7"	"1954.3"	"2378.9"	"1717.5"	"1659.2"	"3801.4"	"4145.6"	"6345.1"	"11396.1"	"10255.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24928"	"DNA-directed RNA polymerase II subunit RPB1 OS=Homo sapiens OX=9606 GN=POLR2A PE=1 SV=2"	"0.000"	""	"13"	"23"	"44"	"23"	"1970"	"217.0"	"7.37"	"7967.26"	"79.59"	"19"	"21"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04990, Pf04992, Pf04997, Pf04998, Pf05000, Pf05001"	"5430"	""	"POLR2A"	"A6NN93; B9EH88; hsa:5430; P24928; Q6NX41"	"Pyrimidine metabolism; Eukaryotic transcription initiation; mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"44"	"0"	"2020.1"	"1864.3"	"2338.8"	"2794.4"	"1924.4"	"2037.2"	"2947.1"	"2989.7"	"3447.2"	"6392.2"	"8742.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H307"	"Pinin OS=Homo sapiens OX=9606 GN=PNN PE=1 SV=5"	"0.000"	""	"26"	"16"	"39"	"16"	"717"	"81.6"	"7.14"	"7420.11"	"79.43"	"15"	"16"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04696, Pf04697"	"5411"	"ENSG00000100941"	"PNN"	"B4DZX8; hsa:5411; O60899; Q53EM7; Q6P5X4; Q7KYL1; Q99738; Q9H307; Q9UHZ9; Q9UQR9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1545.6"	"1248.3"	"1751.8"	"2218.4"	"1518.3"	"1577.8"	"2135.7"	"2139.9"	"2388.2"	"4202.8"	"6584.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y383"	"Putative RNA-binding protein Luc7-like 2 OS=Homo sapiens OX=9606 GN=LUC7L2 PE=1 SV=2"	"0.000"	""	"35"	"15"	"43"	"11"	"392"	"46.5"	"10.01"	"8428.93"	"79.39"	"13"	"15"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"51631"	"ENSG00000146963"	"LUC7L2"	"B7Z500; hsa:51631; Q8IUP9; Q9NVL3; Q9NVN7; Q9UQN1; Q9Y383"	""	""	"0"	"5"	"935.8"	"827.1"	"1133.5"	"1542.1"	"1003.3"	"926.2"	"2165.3"	"2248.6"	"3658.3"	"11544.1"	"14921.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12081"	"Histidine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=HARS1 PE=1 SV=2"	"0.000"	""	"42"	"23"	"41"	"23"	"509"	"57.4"	"5.88"	"6794.22"	"78.96"	"16"	"22"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf03129, Pf13393"	"3035"	"ENSG00000170445"	"HARS1"	"B4DHQ1; B4DY73; D6REN6; hsa:3035; J3KNE5; P12081"	"Allograft rejection"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"711.0"	"591.3"	"801.7"	"966.3"	"679.8"	"843.9"	"1915.4"	"2132.1"	"3457.1"	"12197.1"	"19388.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68104"	"Elongation factor 1-alpha 1 OS=Homo sapiens OX=9606 GN=EEF1A1 PE=1 SV=1"	"0.000"	""	"45"	"17"	"38"	"17"	"462"	"50.1"	"9.01"	"5414.25"	"78.82"	"12"	"15"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"1915"	"ENSG00000156508"	"EEF1A1"	"hsa:1915; P04719; P04720; P68104; Q6IQ15"	"Translation factors; Fragile X syndrome; 2q37 copy number variation syndrome"	"Neutrophil degranulation; Chaperone Mediated Autophagy; Protein methylation; Peptide chain elongation; HSF1 activation; SARS-CoV-1 modulates host translation machinery"	"10"	"0"	"2204.3"	"2358.3"	"1599.5"	"1747.8"	"1566.6"	"1893.7"	"2936.3"	"2991.4"	"4329.1"	"11074.3"	"11188.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49750"	"YLP motif-containing protein 1 OS=Homo sapiens OX=9606 GN=YLPM1 PE=1 SV=4"	"0.000"	""	"10"	"21"	"35"	"21"	"2146"	"241.5"	"6.55"	"5802.75"	"78.51"	"15"	"20"	"other biological processes"	"cytosol;nucleus"	""	"Pf13671"	"56252"	"ENSG00000119596"	"YLPM1"	"hsa:56252; P49750; P49752; Q96I64; Q9P1V7"	""	""	"0"	"0"	"1918.9"	"1655.7"	"1856.2"	"2118.3"	"1655.2"	"1802.0"	"2318.2"	"2416.1"	"2720.2"	"4458.2"	"5139.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21333"	"Filamin-A OS=Homo sapiens OX=9606 GN=FLNA PE=1 SV=4"	"0.000"	""	"8"	"16"	"30"	"14"	"2647"	"280.6"	"6.06"	"5919.78"	"78.22"	"10"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2316"	"ENSG00000196924"	"FLNA"	"E9KL45; hsa:2316; P21333; Q5HY53; Q5HY55; Q8NF52"	"Androgen receptor signaling pathway; Prolactin signaling pathway; Focal adhesion; Hypothesized pathways in pathogenesis of cardiovascular disease; MAPK signaling pathway; IL-4 signaling pathway; Ebola virus infection in host; Joubert syndrome; NPHP1 deletion syndrome"	"OAS antiviral response; Platelet degranulation ; RHO GTPases activate PAKs; GP1b-IX-V activation signalling; Cell-extracellular matrix interactions"	"14"	"2"	"664.9"	"651.3"	"769.5"	"968.1"	"597.1"	"580.1"	"1028.6"	"1091.6"	"1378.6"	"6080.8"	"11460.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14866"	"Heterogeneous nuclear ribonucleoprotein L OS=Homo sapiens OX=9606 GN=HNRNPL PE=1 SV=2"	"0.000"	""	"33"	"12"	"36"	"12"	"589"	"64.1"	"8.22"	"6744.96"	"78.12"	"8"	"12"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"3191"	"ENSG00000104824; ENSG00000282947"	"HNRNPL"	"A6ND69; A6NIT8; hsa:3191; P14866; Q9H3P3"	"mRNA processing; Hippocampal synaptogenesis and neurogenesis"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"0"	"1922.3"	"2168.4"	"2160.3"	"2906.3"	"1815.1"	"1684.1"	"2821.0"	"2921.2"	"3204.6"	"5223.6"	"7195.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51991"	"Heterogeneous nuclear ribonucleoprotein A3 OS=Homo sapiens OX=9606 GN=HNRNPA3 PE=1 SV=2"	"0.000"	""	"28"	"11"	"43"	"9"	"378"	"39.6"	"9.01"	"9124.81"	"77.96"	"9"	"10"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00076"	"220988"	"ENSG00000170144"	"HNRNPA3"	"D3DPF4; hsa:220988; P51991; Q53RW7; Q6URK5"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"1369.4"	"1849.2"	"1501.0"	"1959.5"	"1418.2"	"1232.6"	"2001.7"	"2120.8"	"2312.1"	"3658.8"	"4834.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07900"	"Heat shock protein HSP 90-alpha OS=Homo sapiens OX=9606 GN=HSP90AA1 PE=1 SV=5"	"0.000"	""	"35"	"22"	"40"	"11"	"732"	"84.6"	"5.02"	"5649.92"	"77.69"	"17"	"22"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"3320"	"ENSG00000080824"	"HSP90AA1"	"A8K500; B3KPJ9; hsa:3320; P07900; Q2PP14; Q5CAQ6; Q5CAQ7; Q9BVQ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; TNF-alpha signaling pathway; Corticotropin-releasing hormone signaling pathway; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Aryl hydrocarbon receptor pathway; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Th17 cell differentiation pathway"	"Estrogen-dependent gene expression; Regulation of actin dynamics for phagocytic cup formation; Potential therapeutics for SARS; The role of GTSE1 in G2/M progression after G2 checkpoint; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; Aggrephagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Extra-nuclear estrogen signaling; Neutrophil degranulation; vRNP Assembly; Regulation of necroptotic cell death; Interleukin-4 and Interleukin-13 signaling; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Sema3A PAK dependent Axon repulsion; DDX58/IFIH1-mediated induction of interferon-alpha/beta; PIWI-interacting RNA (piRNA) biogenesis; VEGFR2 mediated vascular permeability; RHOBTB2 GTPase cycle; Chaperone Mediated Autophagy; HSF1 activation; Attenuation phase; eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Uptake and function of diphtheria toxin; Constitutive Signaling by Overexpressed ERBB2; Scavenging by Class F Receptors; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"67"	"1"	"337.3"	"309.3"	"394.7"	"635.3"	"335.1"	"322.1"	"577.8"	"622.6"	"745.9"	"1958.3"	"2880.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13645"	"Keratin, type I cytoskeletal 10 OS=Homo sapiens OX=9606 GN=KRT10 PE=1 SV=6"	"0.000"	""	"33"	"17"	"36"	"13"	"584"	"58.8"	"5.21"	"7746.97"	"77.67"	"15"	"16"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;other molecular function"	"Pf00038"	"3858"	"ENSG00000186395"	"KRT10"	"hsa:3858; P13645; Q14664; Q8N175"	""	"Formation of the cornified envelope"	"2"	"5"	"1952.0"	"2554.2"	"7996.8"	"780.0"	"307.8"	"717.6"	"3888.9"	"2877.7"	"2536.4"	"3943.3"	"5649.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13573"	"SNW domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SNW1 PE=1 SV=1"	"0.000"	""	"40"	"19"	"36"	"19"	"536"	"61.5"	"9.52"	"7572.82"	"77.42"	"15"	"16"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf02731"	"22938"	"ENSG00000100603"	"SNW1"	"A8K8A9; hsa:22938; Q13483; Q13573; Q32N03; Q5D0D6"	"Novel intracellular components of RIG-I-like receptor pathway; Splicing factor NOVA regulated synaptic proteins; Notch signaling pathway"	"mRNA Splicing - Major Pathway; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Pre-NOTCH Transcription and Translation; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"15"	"0"	"2321.9"	"2549.9"	"2360.9"	"3068.3"	"2306.8"	"2226.9"	"3229.2"	"3469.0"	"3818.3"	"7835.7"	"12025.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ35"	"Serine/arginine repetitive matrix protein 2 OS=Homo sapiens OX=9606 GN=SRRM2 PE=1 SV=2"	"0.000"	""	"10"	"17"	"29"	"17"	"2752"	"299.4"	"12.06"	"4926.72"	"77.33"	"12"	"17"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08312"	"23524"	"ENSG00000167978"	"SRRM2"	"A6NKB9; D3DU97; hsa:23524; O15038; O94803; Q6NSL3; Q6PIM3; Q6PK40; Q8IW17; Q96GY7; Q9P0G1; Q9UHA8; Q9UQ35; Q9UQ36; Q9UQ37; Q9UQ38; Q9UQ40"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1001.7"	"848.7"	"1087.8"	"1270.2"	"918.9"	"888.1"	"1340.7"	"1375.2"	"1582.9"	"4426.8"	"7218.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXP5"	"Serrate RNA effector molecule homolog OS=Homo sapiens OX=9606 GN=SRRT PE=1 SV=1"	"0.000"	""	"28"	"22"	"38"	"22"	"876"	"100.6"	"5.96"	"6640.06"	"77.17"	"17"	"19"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04959, Pf12066"	"51593"	"ENSG00000087087"	"SRRT"	"A4D2E5; A4D2E6; A6NK22; B4DJL4; B4DZA6; hsa:51593; O95808; Q32MI4; Q6NT74; Q8TDQ5; Q9BWP6; Q9BXP4; Q9BXP5; Q9Y4S4"	""	"mRNA Splicing - Major Pathway; RNA polymerase II transcribes snRNA genes"	"2"	"0"	"1111.2"	"966.6"	"1254.6"	"1650.0"	"969.7"	"895.7"	"1658.7"	"1759.4"	"2166.6"	"8937.1"	"13855.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55795"	"Heterogeneous nuclear ribonucleoprotein H2 OS=Homo sapiens OX=9606 GN=HNRNPH2 PE=1 SV=1"	"0.000"	""	"32"	"12"	"38"	"5"	"449"	"49.2"	"6.30"	"6421.47"	"76.39"	"10"	"12"	"other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00076, Pf08080"	"3188"	"ENSG00000126945"	"HNRNPH2"	"A1L400; hsa:3188; P55795; Q9HHA7"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"0"	"331.2"	"283.2"	"426.4"	"584.4"	"334.6"	"366.7"	"608.3"	"630.9"	"855.1"	"1770.7"	"2587.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15311"	"Ezrin OS=Homo sapiens OX=9606 GN=EZR PE=1 SV=4"	"0.000"	""	"37"	"24"	"48"	"13"	"586"	"69.4"	"6.27"	"9853.92"	"76.37"	"24"	"20"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"7430"	"ENSG00000092820"	"EZR"	"E1P5A8; hsa:7430; P15311; P23714; Q4VX75; Q96CU8; Q9NSJ4"	"Pathogenic Escherichia coli infection; AGE/RAGE pathway; VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome; CCL18 signaling pathway; Regulation of actin cytoskeleton; GDNF signaling"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Netrin-1 signaling"	"11"	"11"	"2572.9"	"2178.1"	"2680.8"	"2966.2"	"2323.3"	"2383.0"	"4759.3"	"4946.1"	"7918.0"	"12142.9"	"9827.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95602"	"DNA-directed RNA polymerase I subunit RPA1 OS=Homo sapiens OX=9606 GN=POLR1A PE=1 SV=2"	"0.000"	""	"15"	"17"	"33"	"16"	"1720"	"194.7"	"7.03"	"6158.30"	"76.32"	"13"	"15"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"25885"	"ENSG00000068654"	"POLR1A"	"B7Z7T0; D6W5M0; hsa:25885; O95602; Q0VG05; Q9UEH0; Q9UFT9"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"1"	"431.0"	"357.2"	"531.2"	"610.1"	"419.1"	"418.3"	"1570.0"	"1802.0"	"3208.3"	"9438.8"	"12382.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63010"	"AP-2 complex subunit beta OS=Homo sapiens OX=9606 GN=AP2B1 PE=1 SV=1"	"0.000"	""	"19"	"18"	"42"	"9"	"937"	"104.5"	"5.38"	"7719.62"	"76.30"	"16"	"14"	"transport;developmental processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02883, Pf09066"	"163"	"ENSG00000006125"	"AP2B1"	"A6NJP3; hsa:163; P21851; P63010; Q7Z451; Q96J19"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission; Markers of kidney cell lineage; 17q12 copy number variation syndrome"	"Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; Potential therapeutics for SARS; WNT5A-dependent internalization of FZD4; Retrograde neurotrophin signalling; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2"	"20"	"8"	"908.1"	"887.4"	"1143.0"	"1368.4"	"977.2"	"1326.6"	"5718.9"	"6549.7"	"7630.7"	"8651.3"	"8928.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14618"	"Pyruvate kinase PKM OS=Homo sapiens OX=9606 GN=PKM PE=1 SV=4"	"0.000"	""	"38"	"15"	"31"	"15"	"531"	"57.9"	"7.84"	"5260.08"	"75.96"	"11"	"13"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00224, Pf02887"	"5315"	"ENSG00000067225"	"PKM"	"A6NFK3; B2R5N8; B3KRY0; B4DFX8; B4DUU6; hsa:5315; P14618; P14786; Q53GK4; Q96E76; Q9BWB5; Q9UCV6; Q9UPF2"	"Photodynamic therapy-induced HIF-1 survival signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Neutrophil degranulation"	"10"	"0"	"678.8"	"558.6"	"731.4"	"905.3"	"566.9"	"535.9"	"1090.9"	"1169.1"	"1605.0"	"5246.0"	"10420.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78347"	"General transcription factor II-I OS=Homo sapiens OX=9606 GN=GTF2I PE=1 SV=2"	"0.000"	""	"23"	"18"	"36"	"18"	"998"	"112.3"	"6.39"	"8480.82"	"75.89"	"16"	"16"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02946"	"2969"	"ENSG00000263001"	"GTF2I"	"hsa:2969; O14743; O15359; O43546; O43588; O43589; P78347; Q75M85; Q75M86; Q75M87; Q75M88; Q86U51; Q9BSZ4"	"B cell receptor signaling pathway; 7q11.23 copy number variation syndrome; Genetic causes of porto-sinusoidal vascular disease"	""	"3"	"0"	"1231.0"	"1257.2"	"1486.1"	"1913.1"	"1226.3"	"1151.5"	"2247.5"	"2336.5"	"3332.4"	"8368.8"	"11636.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMS4"	"Pre-mRNA-processing factor 19 OS=Homo sapiens OX=9606 GN=PRPF19 PE=1 SV=1"	"0.000"	""	"36"	"12"	"34"	"12"	"504"	"55.1"	"6.61"	"5043.79"	"75.58"	"9"	"12"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04564, Pf08606"	"27339"	"ENSG00000110107"	"PRPF19"	"hsa:27339; Q9UMS4"	""	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of TC-NER Pre-Incision Complex"	"5"	"0"	"399.4"	"414.1"	"484.5"	"584.0"	"398.5"	"395.5"	"1311.2"	"1460.9"	"2386.1"	"8924.7"	"11609.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19338"	"Nucleolin OS=Homo sapiens OX=9606 GN=NCL PE=1 SV=3"	"0.000"	""	"29"	"25"	"48"	"25"	"710"	"76.6"	"4.70"	"9375.96"	"74.95"	"21"	"20"	"developmental processes;other biological processes"	"plasma membrane;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"4691"	"ENSG00000115053"	"NCL"	"hsa:4691; P19338; Q53SK1; Q8NB06; Q9UCF0; Q9UDG1"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"0"	"4593.6"	"4061.4"	"4329.3"	"4733.2"	"3840.0"	"3958.8"	"5697.4"	"5821.3"	"6890.2"	"12029.4"	"13493.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63241"	"Eukaryotic translation initiation factor 5A-1 OS=Homo sapiens OX=9606 GN=EIF5A PE=1 SV=2"	"0.000"	""	"56"	"8"	"40"	"8"	"154"	"16.8"	"5.24"	"7089.95"	"74.30"	"5"	"7"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01287"	"1984"	"ENSG00000132507; ENSG00000288145"	"EIF5A"	"A8K9A0; D3DTP2; hsa:1984; P10159; P63241; Q16182; Q7L7L3; Q7Z4L1; Q9D0G2"	"Translation factors; eIF5A regulation in response to inhibition of the nuclear export system"	"Hypusine synthesis from eIF5A-lysine"	"3"	"0"	"387.9"	"262.0"	"456.5"	"585.6"	"341.3"	"382.5"	"3531.4"	"3631.5"	"6156.7"	"13712.3"	"24666.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86XP3"	"ATP-dependent RNA helicase DDX42 OS=Homo sapiens OX=9606 GN=DDX42 PE=1 SV=1"	"0.000"	""	"25"	"19"	"36"	"19"	"938"	"102.9"	"7.02"	"6855.10"	"74.10"	"15"	"16"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11325"	"ENSG00000198231"	"DDX42"	"A6NML1; A8KA43; hsa:11325; O75619; Q68G51; Q86XP3; Q96BK1; Q96HR7; Q9Y3V8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"1888.8"	"1910.9"	"1929.5"	"2352.7"	"1625.4"	"1753.3"	"2330.4"	"2498.6"	"2755.2"	"4558.4"	"5851.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35637"	"RNA-binding protein FUS OS=Homo sapiens OX=9606 GN=FUS PE=1 SV=1"	"0.000"	""	"24"	"12"	"28"	"9"	"526"	"53.4"	"9.36"	"5141.85"	"74.05"	"8"	"10"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"2521"	"ENSG00000089280"	"FUS"	"hsa:2521; P35637; Q9H4A8"	"MECP2 and associated Rett syndrome; mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"4"	"3"	"2483.8"	"2832.4"	"2441.9"	"2883.3"	"2057.1"	"2112.8"	"3265.2"	"3403.0"	"3706.0"	"6674.7"	"9038.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35611"	"Alpha-adducin OS=Homo sapiens OX=9606 GN=ADD1 PE=1 SV=2"	"0.000"	""	"23"	"15"	"27"	"13"	"737"	"80.9"	"5.83"	"4300.65"	"73.89"	"11"	"15"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"118"	"ENSG00000087274"	"ADD1"	"A2A3N8; A2A3P0; B4DI79; D3DVR3; D3DVR4; D3DVR5; hsa:118; P35611; Q13734; Q14729; Q16156; Q86XM2; Q9UJB6"	""	"XBP1(S) activates chaperone genes; Caspase-mediated cleavage of cytoskeletal proteins; Miscellaneous transport and binding events"	"3"	"2"	"1108.4"	"903.2"	"1037.1"	"1198.0"	"856.2"	"907.0"	"1841.7"	"1927.1"	"3047.3"	"5197.3"	"5606.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06830"	"Peroxiredoxin-1 OS=Homo sapiens OX=9606 GN=PRDX1 PE=1 SV=1"	"0.000"	""	"60"	"16"	"41"	"15"	"199"	"22.1"	"8.13"	"7744.62"	"73.53"	"14"	"14"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"5052"	"ENSG00000117450"	"PRDX1"	"B5BU26; D3DPZ8; hsa:5052; P35703; Q06830; Q2V576; Q5T154; Q5T155"	"Androgen receptor signaling pathway; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway"	"Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes; NFE2L2 regulating anti-oxidant/detoxification enzymes; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"8"	"1"	"1446.1"	"1405.6"	"1914.4"	"2518.2"	"1412.7"	"1487.0"	"2578.0"	"2634.2"	"3397.7"	"8928.0"	"14193.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZW5"	"MAGUK p55 subfamily member 6 OS=Homo sapiens OX=9606 GN=MPP6 PE=1 SV=2"	"0.000"	""	"30"	"16"	"37"	"14"	"540"	"61.1"	"6.18"	"6585.77"	"73.44"	"15"	"16"	"cell organization and biogenesis"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"51678"	"ENSG00000105926"	"PALS2"	"A4D157; hsa:51678; Q9H0E1; Q9NZW5"	""	""	"0"	"2"	"1053.7"	"821.2"	"1049.9"	"1232.9"	"782.8"	"820.5"	"1732.3"	"1794.4"	"2930.7"	"9838.9"	"12887.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52597"	"Heterogeneous nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=HNRNPF PE=1 SV=3"	"0.000"	""	"28"	"13"	"36"	"10"	"415"	"45.6"	"5.58"	"4861.25"	"71.96"	"11"	"12"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf08080"	"3185"	"ENSG00000169813"	"HNRNPF"	"B3KM84; hsa:3185; P52597; Q5T0N2; Q96AU2"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"0"	"2300.5"	"2179.1"	"1922.5"	"2725.1"	"1727.5"	"1969.4"	"3099.4"	"3182.9"	"3741.4"	"5897.4"	"6331.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2L1"	"Exosome complex exonuclease RRP44 OS=Homo sapiens OX=9606 GN=DIS3 PE=1 SV=2"	"0.000"	""	"20"	"18"	"34"	"18"	"958"	"108.9"	"7.14"	"6202.83"	"71.95"	"15"	"16"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00773, Pf13638, Pf17215, Pf17216, Pf17849"	"22894"	"ENSG00000083520"	"DIS3"	"A6NI21; B2RBL2; hsa:22894; Q5W0P7; Q5W0P8; Q658Z7; Q7Z481; Q8WWI2; Q9UG36; Q9Y2L1"	""	"ATF4 activates genes in response to endoplasmic reticulum  stress; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; Major pathway of rRNA processing in the nucleolus and cytosol; KSRP (KHSRP) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"681.6"	"672.0"	"764.7"	"990.8"	"677.2"	"624.5"	"1583.5"	"1757.9"	"2940.9"	"6770.5"	"7101.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKV3"	"Apoptotic chromatin condensation inducer in the nucleus OS=Homo sapiens OX=9606 GN=ACIN1 PE=1 SV=2"	"0.000"	""	"16"	"18"	"39"	"18"	"1341"	"151.8"	"6.43"	"7440.13"	"71.94"	"14"	"15"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf16294"	"22985"	"ENSG00000100813"	"ACIN1"	"B2RTT4; D3DS45; hsa:22985; O75158; Q9UG91; Q9UKV1; Q9UKV2; Q9UKV3"	""	"mRNA Splicing - Major Pathway; Apoptotic cleavage of cellular proteins"	"2"	"0"	"2951.8"	"2760.9"	"3162.2"	"3650.2"	"2532.2"	"2638.2"	"3507.6"	"3512.9"	"3793.4"	"7795.0"	"12061.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L014"	"Probable ATP-dependent RNA helicase DDX46 OS=Homo sapiens OX=9606 GN=DDX46 PE=1 SV=2"	"0.000"	""	"19"	"19"	"39"	"19"	"1031"	"117.3"	"9.29"	"7922.84"	"71.07"	"18"	"17"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"9879"	"ENSG00000145833"	"DDX46"	"hsa:9879; O94894; Q7L014; Q96EI0; Q9Y658"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1201.7"	"1205.5"	"1256.6"	"1463.8"	"1134.6"	"1219.9"	"2267.3"	"2384.1"	"3617.1"	"10843.3"	"16222.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35580"	"Myosin-10 OS=Homo sapiens OX=9606 GN=MYH10 PE=1 SV=3"	"0.000"	""	"10"	"16"	"29"	"12"	"1976"	"228.9"	"5.54"	"5183.92"	"70.47"	"11"	"15"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf00612, Pf01576, Pf02736"	"4628"	"ENSG00000133026"	"MYH10"	"B2RWP9; D3DTS1; F8VTL3; hsa:4628; P35580; Q12989; Q149N3; Q149N4; Q16087; Q4LE45; Q6PK16; Q9BWG0"	"Regulation of actin cytoskeleton"	"EPHA-mediated growth cone collapse; RHO GTPases activate PAKs; RHO GTPases activate CIT; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs"	"7"	"1"	"474.0"	"364.9"	"613.6"	"795.4"	"474.0"	"517.5"	"876.2"	"864.2"	"1215.3"	"4703.3"	"9866.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00688"	"Peptidyl-prolyl cis-trans isomerase FKBP3 OS=Homo sapiens OX=9606 GN=FKBP3 PE=1 SV=1"	"0.000"	""	"42"	"14"	"34"	"14"	"224"	"25.2"	"9.28"	"7631.89"	"70.25"	"13"	"12"	""	"nucleus"	"other molecular function"	"Pf00254, Pf18410"	"2287"	"ENSG00000100442"	"FKBP3"	"B2R4Q9; hsa:2287; Q00688; Q14317"	""	""	"0"	"0"	"2120.9"	"1888.6"	"2095.9"	"2396.9"	"1866.5"	"1991.3"	"3803.6"	"3999.9"	"5083.0"	"9055.5"	"11797.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26368"	"Splicing factor U2AF 65 kDa subunit OS=Homo sapiens OX=9606 GN=U2AF2 PE=1 SV=4"	"0.000"	""	"28"	"11"	"26"	"11"	"475"	"53.5"	"9.09"	"4293.62"	"69.52"	"7"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"11338"	"ENSG00000063244"	"U2AF2"	"hsa:11338; P26368; Q96HC5"	"mRNA processing; Warburg effect modulated by deubiquitinating enzymes and their substrates"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"394.7"	"388.6"	"510.0"	"853.1"	"395.1"	"392.5"	"1260.6"	"1347.3"	"3178.8"	"9670.9"	"12088.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52948"	"Nuclear pore complex protein Nup98-Nup96 OS=Homo sapiens OX=9606 GN=NUP98 PE=1 SV=4"	"0.000"	""	"12"	"17"	"39"	"17"	"1817"	"197.5"	"6.40"	"7568.58"	"69.01"	"16"	"16"	"cell organization and biogenesis;protein metabolism;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04096, Pf12110"	"4928"	"ENSG00000110713"	"NUP98"	"hsa:4928; P52948; Q8IUT2; Q8WYB0; Q96E54; Q9H3Q4; Q9NT02; Q9UF57; Q9UHX0; Q9Y6J4; Q9Y6J5"	"SARS-CoV-2 innate immunity evasion and cell-specific immune response"	""	"1"	"0"	"1434.8"	"1460.9"	"1449.6"	"1836.5"	"1309.8"	"1385.1"	"2133.8"	"2181.4"	"2662.5"	"5302.7"	"7084.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2W1"	"Thyroid hormone receptor-associated protein 3 OS=Homo sapiens OX=9606 GN=THRAP3 PE=1 SV=2"	"0.000"	""	"23"	"21"	"42"	"20"	"955"	"108.6"	"10.15"	"8638.76"	"68.91"	"21"	"17"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9967"	"ENSG00000054118"	"THRAP3"	"D3DPS5; hsa:9967; Q5VTK6; Q9Y2W1"	"Interactome of polycomb repressive complex 2 (PRC2)"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation"	"3"	"1"	"2291.2"	"2243.2"	"2349.6"	"2989.2"	"1976.7"	"2059.4"	"2886.4"	"3014.9"	"3347.9"	"8059.3"	"12842.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q1KMD3"	"Heterogeneous nuclear ribonucleoprotein U-like protein 2 OS=Homo sapiens OX=9606 GN=HNRNPUL2 PE=1 SV=1"	"0.000"	""	"24"	"15"	"34"	"15"	"747"	"85.1"	"4.91"	"6059.00"	"68.79"	"14"	"15"	""	"nucleus;other cell component"	""	"Pf00622, Pf02037, Pf13671"	"221092"	"ENSG00000214753"	"HNRNPUL2"	"hsa:221092; Q1KMD3; Q8N3B3"	""	""	"0"	"0"	"1310.5"	"1387.5"	"1523.6"	"2190.3"	"1256.4"	"1229.0"	"2241.4"	"2369.8"	"2750.4"	"5507.2"	"7907.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33992"	"DNA replication licensing factor MCM5 OS=Homo sapiens OX=9606 GN=MCM5 PE=1 SV=5"	"0.000"	""	"25"	"16"	"34"	"16"	"734"	"82.2"	"8.37"	"6509.70"	"68.67"	"13"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4174"	"ENSG00000100297"	"MCM5"	"hsa:4174; O60785; P33992; Q14578; Q9BTJ4; Q9BWL8"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"10"	"0"	"1039.2"	"890.3"	"1304.1"	"1990.1"	"1098.5"	"1002.5"	"1836.8"	"1990.7"	"2579.5"	"5895.9"	"7994.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52272"	"Heterogeneous nuclear ribonucleoprotein M OS=Homo sapiens OX=9606 GN=HNRNPM PE=1 SV=3"	"0.000"	""	"30"	"18"	"37"	"18"	"730"	"77.5"	"8.70"	"6957.80"	"68.09"	"15"	"15"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf11532"	"4670"	"ENSG00000099783"	"HNRNPM"	"hsa:4670; P52272; Q15584; Q8WZ44; Q96H56; Q9BWL9; Q9Y492"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; FGFR2 alternative splicing"	"4"	"0"	"1757.3"	"1693.1"	"2227.8"	"2846.3"	"1860.6"	"1895.9"	"3167.2"	"3311.7"	"4193.5"	"9334.1"	"14152.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60216"	"Double-strand-break repair protein rad21 homolog OS=Homo sapiens OX=9606 GN=RAD21 PE=1 SV=2"	"0.000"	""	"26"	"14"	"30"	"14"	"631"	"71.6"	"4.65"	"5025.74"	"68.09"	"10"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04824, Pf04825"	"5885"	"ENSG00000164754"	"RAD21"	"A8K0E0; hsa:5885; O60216; Q15001; Q99568"	"Cell cycle; Prion disease pathway; Regulation of sister chromatid separation at the metaphase-anaphase transition; Cohesin complex - Cornelia de Lange syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; 10q22q23 copy number variation"	"Meiotic synapsis; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"13"	"0"	"1071.2"	"1006.2"	"1166.6"	"1365.8"	"939.5"	"970.1"	"1605.0"	"1661.0"	"2014.3"	"5042.3"	"7421.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54136"	"Arginine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=RARS1 PE=1 SV=2"	"0.000"	""	"29"	"16"	"33"	"16"	"660"	"75.3"	"6.68"	"7926.43"	"67.69"	"15"	"15"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00750, Pf03485, Pf05746"	"5917"	"ENSG00000113643"	"RARS1"	"B2RBS9; hsa:5917; P54136; Q53GY4; Q9BWA1"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"3"	"0"	"354.2"	"304.1"	"409.5"	"475.3"	"344.5"	"349.4"	"961.2"	"1106.2"	"1905.1"	"6686.7"	"9262.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30101"	"Protein disulfide-isomerase A3 OS=Homo sapiens OX=9606 GN=PDIA3 PE=1 SV=4"	"0.000"	""	"38"	"15"	"27"	"15"	"505"	"56.7"	"6.35"	"4339.24"	"67.66"	"8"	"14"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"2923"	"ENSG00000167004"	"PDIA3"	"hsa:2923; P30101; Q13453; Q14255; Q8IYF8; Q9UMU7"	"Prion disease pathway"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Calnexin/calreticulin cycle"	"4"	"0"	"279.6"	"289.8"	"331.7"	"420.1"	"287.4"	"318.6"	"604.7"	"680.9"	"837.2"	"5676.1"	"11748.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23921"	"Ribonucleoside-diphosphate reductase large subunit OS=Homo sapiens OX=9606 GN=RRM1 PE=1 SV=1"	"0.000"	""	"26"	"13"	"26"	"13"	"792"	"90.0"	"7.15"	"5010.56"	"67.44"	"9"	"13"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00317, Pf02867, Pf03477"	"6240"	"ENSG00000167325"	"RRM1"	"hsa:6240; P23921; Q9UNN2"	"Fluoropyrimidine activity; Retinoblastoma gene in cancer; Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"4"	"0"	"279.2"	"244.2"	"286.6"	"405.8"	"245.2"	"252.9"	"718.5"	"836.3"	"1456.5"	"4140.5"	"5803.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUM0"	"Nuclear pore complex protein Nup133 OS=Homo sapiens OX=9606 GN=NUP133 PE=1 SV=2"	"0.000"	""	"23"	"20"	"39"	"20"	"1156"	"128.9"	"5.10"	"9048.62"	"67.06"	"18"	"17"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf03177"	"55746"	"ENSG00000069248"	"NUP133"	"B2RAZ8; hsa:55746; Q5T8N0; Q8WUM0; Q9H9W2; Q9NV71; Q9NVC4"	"Ciliary landscape"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"36"	"0"	"1765.5"	"1485.1"	"1793.4"	"2242.4"	"1505.8"	"1603.0"	"2567.3"	"2641.9"	"3373.2"	"6974.6"	"9162.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAF3"	"WD repeat-containing protein 48 OS=Homo sapiens OX=9606 GN=WDR48 PE=1 SV=1"	"0.000"	""	"33"	"15"	"30"	"15"	"677"	"76.2"	"7.03"	"5001.48"	"66.97"	"12"	"15"	"DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf11816"	"57599"	"ENSG00000114742"	"WDR48"	"B4DM86; B4DQI2; B4DY84; hsa:57599; Q63HJ2; Q658Y1; Q8N3Z1; Q8TAF3; Q9NSK8; Q9P279"	"DNA repair pathways, full network"	"Ub-specific processing proteases; Fanconi Anemia Pathway; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins; Recognition of DNA damage by PCNA-containing replication complex"	"5"	"0"	"385.8"	"359.7"	"472.6"	"556.5"	"438.2"	"479.8"	"1473.8"	"1771.9"	"2754.5"	"6377.3"	"6317.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48643"	"T-complex protein 1 subunit epsilon OS=Homo sapiens OX=9606 GN=CCT5 PE=1 SV=1"	"0.000"	""	"28"	"15"	"23"	"15"	"541"	"59.6"	"5.66"	"4021.36"	"66.83"	"7"	"13"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00118"	"22948"	"ENSG00000150753"	"CCT5"	"A8JZY8; A8K2X8; B4DYD8; hsa:22948; P48643"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"727.1"	"576.4"	"816.5"	"1083.5"	"653.3"	"655.0"	"1320.2"	"1360.7"	"1752.7"	"9558.9"	"20348.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB6"	"LIM domain and actin-binding protein 1 OS=Homo sapiens OX=9606 GN=LIMA1 PE=1 SV=1"	"0.000"	""	"27"	"13"	"25"	"13"	"759"	"85.2"	"6.84"	"4070.08"	"66.25"	"8"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412"	"51474"	"ENSG00000050405"	"LIMA1"	"B2RB09; hsa:51474; Q2TAN7; Q59FE8; Q9BVF2; Q9H8J1; Q9HBN5; Q9NX96; Q9NXC3; Q9NXU6; Q9P0H8; Q9UHB5; Q9UHB6"	""	""	"0"	"0"	"1024.1"	"967.1"	"1004.2"	"1220.0"	"955.5"	"1080.4"	"1516.1"	"1542.1"	"1974.6"	"4822.4"	"5556.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95747"	"Serine/threonine-protein kinase OSR1 OS=Homo sapiens OX=9606 GN=OXSR1 PE=1 SV=1"	"0.000"	""	"28"	"11"	"26"	"10"	"527"	"58.0"	"6.43"	"4569.77"	"66.12"	"8"	"10"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"9943"	"ENSG00000172939"	"OXSR1"	"hsa:9943; O95747; Q3LR53; Q7Z501; Q9UPQ1"	""	""	"0"	"2"	"184.6"	"173.9"	"244.1"	"307.6"	"204.2"	"215.8"	"750.1"	"850.0"	"1600.8"	"5562.3"	"7916.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VP6"	"Cullin-associated NEDD8-dissociated protein 1 OS=Homo sapiens OX=9606 GN=CAND1 PE=1 SV=2"	"0.000"	""	"15"	"13"	"30"	"13"	"1230"	"136.3"	"5.78"	"6209.67"	"66.05"	"11"	"13"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08623"	"55832"	"ENSG00000111530"	"CAND1"	"B2RAU3; hsa:55832; O94918; Q6PIY4; Q86VP6; Q8NDJ4; Q96JZ9; Q96T19; Q9BTC4; Q9H0G2; Q9P0H7; Q9UF85"	"Endoderm differentiation"	"Neutrophil degranulation; Neddylation; Iron uptake and transport"	"4"	"0"	"390.7"	"380.4"	"441.3"	"564.6"	"377.4"	"395.7"	"1084.8"	"1178.0"	"2364.7"	"6484.1"	"8100.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50570"	"Dynamin-2 OS=Homo sapiens OX=9606 GN=DNM2 PE=1 SV=2"	"0.000"	""	"21"	"14"	"34"	"11"	"870"	"98.0"	"7.44"	"6162.54"	"65.92"	"13"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"1785"	"ENSG00000079805"	"DNM2"	"A8K1B6; E7EV30; E9PEQ4; hsa:1785; K7ESI9; P50570; Q5I0Y0; Q7Z5S3; Q9UPH4"	"Synaptic vesicle pathway; Fragile X syndrome; Intracellular trafficking proteins involved in CMT neuropathy"	"Recycling pathway of L1; MHC class II antigen presentation; Clathrin-mediated endocytosis; Lysosome Vesicle Biogenesis; NGF-stimulated transcription; Golgi Associated Vesicle Biogenesis; Toll Like Receptor 4 (TLR4) Cascade; NOSTRIN mediated eNOS trafficking; Retrograde neurotrophin signalling; Formation of annular gap junctions"	"14"	"4"	"433.5"	"410.6"	"543.4"	"667.7"	"464.5"	"524.3"	"1138.7"	"1252.6"	"1807.3"	"4823.6"	"6850.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99729"	"Heterogeneous nuclear ribonucleoprotein A/B OS=Homo sapiens OX=9606 GN=HNRNPAB PE=1 SV=2"	"0.000"	""	"26"	"12"	"37"	"11"	"332"	"36.2"	"8.21"	"6596.73"	"65.88"	"11"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08143"	"3182"	"ENSG00000197451"	"HNRNPAB"	"B3KNN5; D3DWP7; hsa:3182; Q04150; Q8N7U3; Q99729; Q9BQ99"	"Pre-implantation embryo; mRNA processing"	""	"2"	"0"	"2674.4"	"2565.7"	"3134.5"	"3578.4"	"2475.0"	"2312.6"	"3501.1"	"3462.0"	"3719.3"	"5858.5"	"8550.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUQ8"	"Probable ATP-dependent RNA helicase DDX23 OS=Homo sapiens OX=9606 GN=DDX23 PE=1 SV=3"	"0.000"	""	"24"	"18"	"40"	"18"	"820"	"95.5"	"9.55"	"7239.92"	"65.81"	"16"	"16"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"9416"	"ENSG00000174243"	"DDX23"	"B2R600; B4DH15; hsa:9416; O43188; Q9BUQ8"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"1828.3"	"1631.0"	"1998.6"	"2408.4"	"1682.2"	"1616.1"	"2565.6"	"2684.1"	"3360.4"	"10117.3"	"16624.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75533"	"Splicing factor 3B subunit 1 OS=Homo sapiens OX=9606 GN=SF3B1 PE=1 SV=3"	"0.000"	""	"12"	"16"	"33"	"16"	"1304"	"145.7"	"7.09"	"6389.10"	"65.62"	"14"	"14"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08920"	"23451"	"ENSG00000115524"	"SF3B1"	"E9PCH3; hsa:23451; O75533"	"mRNA processing; 10q11.21q11.23 copy number variation syndrome"	"mRNA Splicing - Major Pathway; B-WICH complex positively regulates rRNA expression; mRNA Splicing - Minor Pathway"	"5"	"0"	"1382.3"	"1073.8"	"1592.4"	"1872.1"	"1344.3"	"1372.4"	"1934.3"	"1924.6"	"2221.1"	"4863.6"	"8502.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92917"	"G-patch domain and KOW motifs-containing protein OS=Homo sapiens OX=9606 GN=GPKOW PE=1 SV=2"	"0.000"	""	"40"	"13"	"27"	"13"	"476"	"52.2"	"6.15"	"5105.94"	"65.55"	"9"	"12"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00467, Pf12656"	"27238"	"ENSG00000068394"	"GPKOW"	"hsa:27238; Q59EK5; Q92917; Q9BQA8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"572.6"	"491.7"	"654.9"	"780.1"	"565.1"	"584.3"	"1474.9"	"1589.6"	"2515.7"	"6018.5"	"7968.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31942"	"Heterogeneous nuclear ribonucleoprotein H3 OS=Homo sapiens OX=9606 GN=HNRNPH3 PE=1 SV=2"	"0.000"	""	"29"	"9"	"31"	"8"	"346"	"36.9"	"6.87"	"5092.83"	"65.26"	"6"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"3189"	"ENSG00000096746"	"HNRNPH3"	"A8K682; B3KRE1; hsa:3189; P31942; Q9BSX1; Q9NP53; Q9NP96; Q9NPA7; Q9NPI4; Q9UFU4; Q9Y4J5"	""	""	"0"	"0"	"649.3"	"681.9"	"787.4"	"1131.1"	"659.2"	"661.8"	"1070.3"	"1051.6"	"1296.5"	"2528.1"	"3480.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99832"	"T-complex protein 1 subunit eta OS=Homo sapiens OX=9606 GN=CCT7 PE=1 SV=2"	"0.000"	""	"36"	"14"	"24"	"14"	"543"	"59.3"	"7.65"	"2767.62"	"64.47"	"7"	"12"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"10574"	"ENSG00000135624"	"CCT7"	"A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7; hsa:10574; O14871; Q6FI26; Q99832"	"VEGFA-VEGFR2 signaling; 16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; RHOBTB1 GTPase cycle; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"9"	"0"	"350.5"	"291.1"	"447.1"	"525.1"	"349.3"	"341.6"	"681.7"	"707.5"	"1011.5"	"4777.3"	"9817.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92804"	"TATA-binding protein-associated factor 2N OS=Homo sapiens OX=9606 GN=TAF15 PE=1 SV=1"	"0.000"	""	"16"	"9"	"24"	"6"	"592"	"61.8"	"8.02"	"2877.83"	"63.80"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641"	"8148"	"ENSG00000270647; ENSG00000276833"	"TAF15"	"B2R837; hsa:8148; Q86X94; Q92751; Q92804"	"17q12 copy number variation syndrome"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"10"	"0"	"506.2"	"424.2"	"548.7"	"752.2"	"455.9"	"431.1"	"718.3"	"714.0"	"819.6"	"1234.6"	"1944.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40227"	"T-complex protein 1 subunit zeta OS=Homo sapiens OX=9606 GN=CCT6A PE=1 SV=3"	"0.000"	""	"40"	"15"	"27"	"15"	"531"	"58.0"	"6.68"	"4611.04"	"63.31"	"9"	"12"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"908"	"ENSG00000146731"	"CCT6A"	"A6NCD2; hsa:908; P40227; Q3KP28; Q75LP4; Q96S46"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; RHOBTB2 GTPase cycle; Folding of actin by CCT/TriC"	"7"	"0"	"493.0"	"454.0"	"594.2"	"754.3"	"456.9"	"492.7"	"941.9"	"1035.2"	"1491.7"	"7927.5"	"15412.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23246"	"Splicing factor, proline- and glutamine-rich OS=Homo sapiens OX=9606 GN=SFPQ PE=1 SV=2"	"0.000"	""	"17"	"12"	"38"	"11"	"707"	"76.1"	"9.44"	"8853.50"	"62.89"	"12"	"11"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"6421"	"ENSG00000116560"	"SFPQ"	"hsa:6421; P23246; P30808; Q5SZ71"	"mRNA processing; Type 2 papillary renal cell carcinoma"	"Suppression of apoptosis; PTK6 Regulates Proteins Involved in RNA Processing"	"4"	"1"	"2286.5"	"2117.3"	"2401.7"	"2887.6"	"2042.1"	"2157.1"	"2887.7"	"2951.5"	"3323.5"	"5414.4"	"7106.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15233"	"Non-POU domain-containing octamer-binding protein OS=Homo sapiens OX=9606 GN=NONO PE=1 SV=4"	"0.000"	""	"26"	"12"	"34"	"10"	"471"	"54.2"	"8.95"	"6297.11"	"62.54"	"10"	"12"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08075"	"4841"	"ENSG00000147140"	"NONO"	"B7Z4C2; D3DVV4; F5GYZ3; hsa:4841; O00201; P30807; Q12786; Q15233; Q9BQC5"	"mRNA processing"	""	"1"	"0"	"2443.9"	"2086.3"	"2559.5"	"2940.0"	"2213.7"	"2307.2"	"2918.7"	"2906.0"	"3214.7"	"4749.2"	"6496.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBU9"	"Nuclear RNA export factor 1 OS=Homo sapiens OX=9606 GN=NXF1 PE=1 SV=1"	"0.000"	""	"26"	"10"	"23"	"10"	"619"	"70.1"	"8.51"	"4144.72"	"62.53"	"8"	"10"	"other metabolic processes;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02136, Pf03943, Pf09162"	"10482"	"ENSG00000162231"	"NXF1"	"B4E269; hsa:10482; Q99799; Q9UBU9; Q9UQL2"	"mRNA processing"	"Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"615.1"	"579.5"	"699.7"	"808.6"	"640.7"	"670.0"	"940.8"	"965.0"	"1162.8"	"2292.5"	"3658.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UP2"	"Kinectin OS=Homo sapiens OX=9606 GN=KTN1 PE=1 SV=1"	"0.000"	""	"15"	"15"	"28"	"14"	"1357"	"156.2"	"5.64"	"5501.66"	"62.28"	"14"	"14"	"transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"cytoskeletal activity"	"Pf05104"	"3895"	"ENSG00000126777"	"KTN1"	"B4DZ88; hsa:3895; Q13999; Q14707; Q15387; Q17RZ5; Q5GGW3; Q86UP2; Q86W57"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RND2 GTPase cycle; RND3 GTPase cycle; RHO GTPases activate KTN1"	"11"	"1"	"509.1"	"474.7"	"636.4"	"750.4"	"549.4"	"514.0"	"1045.0"	"1105.5"	"1703.2"	"4392.3"	"6344.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43852"	"Calumenin OS=Homo sapiens OX=9606 GN=CALU PE=1 SV=2"	"0.000"	""	"58"	"15"	"27"	"15"	"315"	"37.1"	"4.64"	"5213.66"	"61.88"	"12"	"14"	""	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf13833"	"813"	"ENSG00000128595"	"CALU"	"B3KPG9; D6QS48; D6QS49; D6QS50; D6QS51; D6QS52; D6QS53; D6QS54; D6QS55; D6QS56; D6QS57; D6QS58; D6QS59; F5H1Q9; F5H879; hsa:813; O43852; O60456; Q6FHB9; Q96RL3; Q9NR43"	"NOTCH1 regulation of endothelial cell calcification; VEGFA-VEGFR2 signaling"	"Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"5"	"0"	"1866.1"	"1601.9"	"2041.3"	"2095.5"	"1726.4"	"1891.9"	"2129.2"	"2089.5"	"2224.8"	"2576.2"	"2926.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14204"	"Cytoplasmic dynein 1 heavy chain 1 OS=Homo sapiens OX=9606 GN=DYNC1H1 PE=1 SV=5"	"0.000"	""	"5"	"17"	"32"	"17"	"4646"	"532.1"	"6.40"	"5639.34"	"61.79"	"14"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03028, Pf08385, Pf08393, Pf12774, Pf12775, Pf12777, Pf12780, Pf12781, Pf17852, Pf18198, Pf18199"	"1778"	"ENSG00000197102"	"DYNC1H1"	"B0I1R0; hsa:1778; Q14204; Q6DKQ7; Q8WU28; Q92814; Q9Y4G5"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Neutrophil degranulation; MHC class II antigen presentation; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"23"	"0"	"529.3"	"444.9"	"603.9"	"739.4"	"494.9"	"542.6"	"935.0"	"973.3"	"1413.1"	"4986.9"	"7747.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTJ3"	"Structural maintenance of chromosomes protein 4 OS=Homo sapiens OX=9606 GN=SMC4 PE=1 SV=2"	"0.000"	""	"16"	"17"	"32"	"17"	"1288"	"147.1"	"6.79"	"5839.34"	"61.29"	"14"	"16"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10051"	"ENSG00000113810"	"SMC4"	"A6NLT9; D3DNL8; hsa:10051; O95752; Q8NDL4; Q9NTJ3; Q9UNT9"	"Ciliary landscape"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"1460.6"	"1424.5"	"1488.1"	"1619.1"	"1382.7"	"1485.9"	"2167.1"	"2194.5"	"2844.7"	"5319.5"	"6648.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31948"	"Stress-induced-phosphoprotein 1 OS=Homo sapiens OX=9606 GN=STIP1 PE=1 SV=1"	"0.000"	""	"31"	"15"	"27"	"15"	"543"	"62.6"	"6.80"	"3899.25"	"61.11"	"8"	"15"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf13181, Pf17830"	"10963"	"ENSG00000168439"	"STIP1"	"B4DM70; F5H0T1; G3XAD8; hsa:10963; P31948; Q3ZCU9; Q5TZU9"	"VEGFA-VEGFR2 signaling"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RND1 GTPase cycle"	"3"	"0"	"699.1"	"777.9"	"816.4"	"1177.3"	"715.0"	"687.4"	"1417.2"	"1482.2"	"1893.1"	"7839.8"	"17102.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AC1"	"Fermitin family homolog 2 OS=Homo sapiens OX=9606 GN=FERMT2 PE=1 SV=1"	"0.000"	""	"20"	"12"	"26"	"12"	"680"	"77.8"	"6.70"	"4533.85"	"60.92"	"8"	"12"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf18124"	"10979"	"ENSG00000073712"	"FERMT2"	"B5TJY2; hsa:10979; Q14840; Q86TY7; Q96AC1"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; Cell-extracellular matrix interactions"	"3"	"0"	"242.9"	"198.7"	"317.8"	"325.4"	"273.6"	"320.5"	"1169.0"	"1361.8"	"2196.5"	"7881.2"	"11430.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30876"	"DNA-directed RNA polymerase II subunit RPB2 OS=Homo sapiens OX=9606 GN=POLR2B PE=1 SV=1"	"0.000"	""	"18"	"18"	"34"	"18"	"1174"	"133.8"	"6.87"	"7174.46"	"60.57"	"18"	"16"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"5431"	"ENSG00000047315"	"POLR2B"	"A8K1A8; hsa:5431; P30876; Q8IZ61"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"1627.4"	"1533.1"	"1748.9"	"2169.6"	"1420.0"	"1519.0"	"2272.9"	"2381.3"	"2634.6"	"5105.4"	"6488.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75131"	"Copine-3 OS=Homo sapiens OX=9606 GN=CPNE3 PE=1 SV=1"	"0.000"	""	"22"	"9"	"20"	"9"	"537"	"60.1"	"5.85"	"1753.86"	"59.91"	"4"	"9"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00168, Pf07002"	"8895"	"ENSG00000085719"	"CPNE3"	"A8KA47; hsa:8895; O75131; Q8IYA1"	""	"Neutrophil degranulation; Glycerophospholipid biosynthesis"	"2"	"0"	"196.4"	"178.0"	"250.4"	"363.0"	"205.1"	"224.8"	"389.8"	"413.2"	"628.3"	"2395.8"	"10340.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96P16"	"Regulation of nuclear pre-mRNA domain-containing protein 1A OS=Homo sapiens OX=9606 GN=RPRD1A PE=1 SV=1"	"0.000"	""	"48"	"16"	"32"	"13"	"312"	"35.7"	"7.55"	"7017.23"	"59.78"	"13"	"13"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"55197"	"ENSG00000141425"	"RPRD1A"	"A8KA42; B2RBA3; hsa:55197; Q7Z5G8; Q96FY9; Q96P16; Q9NVL4"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"3"	"1296.2"	"1203.7"	"1510.8"	"2260.1"	"1133.8"	"1218.5"	"2042.1"	"2096.7"	"2641.1"	"4732.9"	"5168.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07955"	"Serine/arginine-rich splicing factor 1 OS=Homo sapiens OX=9606 GN=SRSF1 PE=1 SV=2"	"0.000"	""	"48"	"14"	"32"	"14"	"248"	"27.7"	"10.36"	"5010.19"	"59.35"	"12"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6426"	"ENSG00000136450"	"SRSF1"	"B2R6Z7; D3DTZ3; hsa:6426; Q07955; Q13809"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"7"	"0"	"1802.7"	"1917.3"	"1624.3"	"2086.7"	"1459.2"	"1408.0"	"2123.8"	"2346.7"	"2470.0"	"4098.8"	"5035.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1J9"	"Parafibromin OS=Homo sapiens OX=9606 GN=CDC73 PE=1 SV=1"	"0.000"	""	"40"	"18"	"33"	"18"	"531"	"60.5"	"9.61"	"5527.59"	"58.17"	"15"	"18"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf05179, Pf16050"	"79577"	"ENSG00000134371"	"CDC73"	"A6NLZ8; B2RBR2; hsa:79577; Q6P1J9; Q6PK51; Q96A07; Q9H245; Q9H5L7"	"Endoderm differentiation"	"Hedgehog 'on' state; RNA Polymerase II Pre-transcription Events; Formation of the beta-catenin:TCF transactivating complex; E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex"	"7"	"0"	"1963.6"	"1862.1"	"2059.4"	"2520.8"	"1806.3"	"1906.2"	"2680.1"	"2789.0"	"3211.2"	"5391.8"	"6691.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71DI3"	"Histone H3.2 OS=Homo sapiens OX=9606 GN=H3C15 PE=1 SV=3"	"0.000"	""	"55"	"8"	"27"	"1"	"136"	"15.4"	"11.27"	"4166.28"	"57.77"	"7"	"8"	"cell organization and biogenesis"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"126961; 333932; 653604"	"ENSG00000183598; ENSG00000203811; ENSG00000203852"	"H3C13; H3C14; H3C15"	"A2BDF6; A6NFS4; hsa:126961; hsa:333932; hsa:653604; Q6B053; Q71DI3"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis; Interleukin-7 signaling; Factors involved in megakaryocyte development and platelet production; RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines"	"36"	"0"	"17.4"	"17.6"	"18.6"	"27.6"	"13.9"	"14.7"	"27.5"	"37.0"	"52.1"	"134.0"	"196.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00159"	"Unconventional myosin-Ic OS=Homo sapiens OX=9606 GN=MYO1C PE=1 SV=4"	"0.000"	""	"15"	"13"	"28"	"12"	"1063"	"121.6"	"9.41"	"6369.17"	"57.52"	"11"	"13"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4641"	"ENSG00000197879"	"MYO1C"	"hsa:4641; O00159; Q4LE56; Q6NVJ7; Q86Y95"	"VEGFA-VEGFR2 signaling; Insulin signaling; 10q11.21q11.23 copy number variation syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"8"	"1"	"454.6"	"395.7"	"507.7"	"589.1"	"438.9"	"518.1"	"1307.4"	"1453.7"	"2410.4"	"3914.1"	"4376.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43719"	"HIV Tat-specific factor 1 OS=Homo sapiens OX=9606 GN=HTATSF1 PE=1 SV=1"	"0.000"	""	"21"	"11"	"25"	"11"	"755"	"85.8"	"4.40"	"4822.52"	"57.45"	"8"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00076"	"27336"	"ENSG00000102241"	"HTATSF1"	"D3DWG9; hsa:27336; O43719; Q59G06; Q99730"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"988.1"	"823.0"	"1152.0"	"1293.7"	"962.5"	"905.4"	"1460.7"	"1516.7"	"1946.1"	"4825.1"	"8247.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15365"	"Poly(rC)-binding protein 1 OS=Homo sapiens OX=9606 GN=PCBP1 PE=1 SV=2"	"0.000"	""	"35"	"9"	"19"	"4"	"356"	"37.5"	"7.09"	"2984.47"	"57.43"	"6"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5093"	"ENSG00000169564"	"PCBP1"	"hsa:5093; Q13157; Q14975; Q15365"	"Ferroptosis"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway"	"3"	"0"	"164.5"	"154.9"	"206.7"	"290.7"	"153.8"	"107.5"	"292.9"	"317.9"	"431.5"	"840.8"	"1113.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2J2"	"Band 4.1-like protein 3 OS=Homo sapiens OX=9606 GN=EPB41L3 PE=1 SV=2"	"0.000"	""	"19"	"17"	"31"	"13"	"1087"	"120.6"	"5.19"	"5688.74"	"57.32"	"15"	"15"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"23136"	"ENSG00000082397"	"EPB41L3"	"B7Z4I5; F5GX05; hsa:23136; O95713; Q9BRP5; Q9Y2J2"	"Splicing factor NOVA regulated synaptic proteins"	"Neurexins and neuroligins; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"0"	"1362.1"	"1170.3"	"1342.0"	"1494.8"	"1137.8"	"1206.7"	"2257.4"	"2465.6"	"3342.9"	"2846.8"	"2772.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15046"	"Lysine--tRNA ligase OS=Homo sapiens OX=9606 GN=KARS1 PE=1 SV=3"	"0.000"	""	"25"	"14"	"27"	"14"	"597"	"68.0"	"6.35"	"5316.14"	"57.12"	"13"	"14"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336"	"3735"	"ENSG00000065427"	"KARS1"	"A8MSK1; D3DUK4; hsa:3735; O14946; Q15046; Q96J25; Q9HB23"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"3"	"0"	"753.5"	"639.5"	"825.5"	"944.4"	"690.2"	"700.3"	"1563.6"	"1670.8"	"2711.2"	"7614.0"	"8074.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25705"	"ATP synthase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1A PE=1 SV=1"	"0.000"	""	"21"	"9"	"29"	"9"	"553"	"59.7"	"9.13"	"6251.18"	"56.65"	"8"	"9"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf00306, Pf02874"	"498"	"ENSG00000152234"	"ATP5F1A"	"A8K092; B4DY56; hsa:498; K7ENP3; P25705; Q53XX6; Q8IXV2; Q96FB4; Q96HW2; Q96IR6; Q9BTV8"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"6"	"0"	"580.9"	"526.3"	"668.3"	"839.5"	"516.8"	"591.5"	"1139.4"	"1234.5"	"1678.0"	"5193.0"	"7888.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94826"	"Mitochondrial import receptor subunit TOM70 OS=Homo sapiens OX=9606 GN=TOMM70 PE=1 SV=1"	"0.000"	""	"25"	"15"	"29"	"15"	"608"	"67.4"	"7.12"	"6289.38"	"56.21"	"14"	"13"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00515, Pf13181"	"9868"	"ENSG00000154174"	"TOMM70"	"D3DN48; hsa:9868; O94826"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 B.1.1.7 variant antagonises innate immune activation; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"Ub-specific processing proteases; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Mitochondrial protein import; DDX58/IFIH1-mediated induction of interferon-alpha/beta; SARS-CoV-1 activates/modulates innate immune responses; PINK1-PRKN Mediated Mitophagy"	"9"	"0"	"610.6"	"544.5"	"763.8"	"845.4"	"661.8"	"638.2"	"1553.5"	"1719.8"	"3246.4"	"7330.9"	"9810.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35908"	"Keratin, type II cytoskeletal 2 epidermal OS=Homo sapiens OX=9606 GN=KRT2 PE=1 SV=2"	"0.000"	""	"22"	"15"	"33"	"11"	"639"	"65.4"	"8.00"	"6569.31"	"55.78"	"15"	"14"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity"	"Pf00038, Pf16208"	"3849"	"ENSG00000172867"	"KRT2"	"hsa:3849; P35908; Q4VAQ2"	""	"Formation of the cornified envelope"	"2"	"2"	"2469.0"	"2330.5"	"4953.0"	"594.6"	"317.3"	"376.2"	"2970.2"	"2455.5"	"1985.3"	"2463.6"	"2540.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43143"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX15 OS=Homo sapiens OX=9606 GN=DHX15 PE=1 SV=2"	"0.000"	""	"18"	"13"	"26"	"13"	"795"	"90.9"	"7.46"	"4394.42"	"55.75"	"10"	"12"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"1665"	"ENSG00000109606"	"DHX15"	"hsa:1665; O43143; Q9NQT7"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"410.6"	"346.4"	"510.0"	"699.7"	"427.4"	"444.8"	"780.5"	"843.8"	"1284.6"	"3819.4"	"6239.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49959"	"Double-strand break repair protein MRE11 OS=Homo sapiens OX=9606 GN=MRE11 PE=1 SV=3"	"0.000"	""	"20"	"13"	"29"	"13"	"708"	"80.5"	"5.90"	"6115.13"	"55.52"	"12"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00149, Pf04152"	"4361"	"ENSG00000020922"	"MRE11"	"B3KTC7; hsa:4361; O43475; P49959"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; Joubert syndrome; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Cytosolic sensors of pathogen-associated DNA ; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks; IRF3-mediated induction of type I IFN"	"32"	"0"	"1132.3"	"795.6"	"1266.3"	"1449.8"	"1054.2"	"1037.3"	"1585.0"	"1601.8"	"2047.0"	"4583.1"	"7253.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60716"	"Catenin delta-1 OS=Homo sapiens OX=9606 GN=CTNND1 PE=1 SV=1"	"0.000"	""	"22"	"17"	"32"	"17"	"968"	"108.1"	"6.23"	"7219.40"	"55.44"	"14"	"13"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00514"	"1500"	"ENSG00000198561"	"CTNND1"	"A8K939; hsa:1500; O15088; O60713; O60714; O60715; O60716; O60935; Q6DHZ7; Q6RBX8; Q9UP71; Q9UP72; Q9UP73"	"VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency"	"VEGFR2 mediated vascular permeability; Adherens junctions interactions; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions"	"8"	"0"	"1650.7"	"1505.3"	"1677.7"	"2032.1"	"1336.4"	"1413.8"	"2399.8"	"2450.6"	"3197.2"	"7298.8"	"9853.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11908"	"Ribose-phosphate pyrophosphokinase 2 OS=Homo sapiens OX=9606 GN=PRPS2 PE=1 SV=2"	"0.000"	""	"35"	"10"	"23"	"3"	"318"	"34.7"	"6.61"	"4825.91"	"55.26"	"8"	"10"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf13793, Pf14572"	"5634"	"ENSG00000101911"	"PRPS2"	"hsa:5634; P11908; Q0VDH9; Q0VDI0; Q15245; Q2TAK7"	""	"5-Phosphoribose 1-diphosphate biosynthesis"	"1"	"0"	"195.7"	"161.4"	"239.0"	"237.1"	"170.4"	"215.4"	"446.0"	"469.7"	"600.0"	"1121.3"	"1575.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6T3"	"RNA polymerase II-associated protein 3 OS=Homo sapiens OX=9606 GN=RPAP3 PE=1 SV=2"	"0.000"	""	"25"	"14"	"26"	"14"	"665"	"75.7"	"6.84"	"5499.56"	"55.26"	"11"	"13"	"other biological processes"	"cytosol;other cell component"	""	"Pf00515, Pf13176, Pf13181, Pf13877"	"79657"	"ENSG00000005175"	"RPAP3"	"B4DRW9; hsa:79657; Q6PHR5; Q9H6T3"	""	""	"0"	"0"	"286.4"	"279.7"	"339.9"	"398.4"	"293.6"	"299.4"	"973.7"	"1023.8"	"1974.2"	"5852.0"	"6600.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60610"	"Protein diaphanous homolog 1 OS=Homo sapiens OX=9606 GN=DIAPH1 PE=1 SV=2"	"0.000"	""	"15"	"17"	"33"	"17"	"1272"	"141.3"	"5.41"	"7570.25"	"55.22"	"17"	"14"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02181, Pf06346, Pf06367, Pf06371"	"1729"	"ENSG00000131504"	"DIAPH1"	"A6NF18; B7ZKW2; E9PEZ2; hsa:1729; O60610; Q17RN4; Q59FH8; Q9UC76"	"Microtubule cytoskeleton regulation; AGE/RAGE pathway; Focal adhesion; Type 2 papillary renal cell carcinoma; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RHO GTPases Activate Formins; RHOB GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; ERBB2 Regulates Cell Motility"	"14"	"0"	"1752.4"	"1537.3"	"1893.3"	"2204.1"	"1533.8"	"1635.7"	"2117.6"	"2213.9"	"2418.1"	"4377.4"	"5245.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07157"	"Tight junction protein ZO-1 OS=Homo sapiens OX=9606 GN=TJP1 PE=1 SV=3"	"0.000"	""	"12"	"15"	"28"	"15"	"1748"	"195.3"	"6.70"	"5700.70"	"55.10"	"13"	"13"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf00791, Pf07653"	"7082"	"ENSG00000104067; ENSG00000277401"	"TJP1"	"B4E3K1; hsa:7082; Q07157; Q2NKP3; Q4ZGJ6"	"Epithelial to mesenchymal transition in colorectal cancer; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; Disruption of postsynaptic signaling by CNV; 1q21.1 copy number variation syndrome; CKAP4 signaling pathway map; 15q11q13 copy number variation"	"RUNX1 regulates expression of components of tight junctions; Signaling by Hippo; Regulation of gap junction activity; SARS-CoV-2 targets PDZ proteins in cell-cell junction; Apoptotic cleavage of cell adhesion  proteins"	"12"	"0"	"885.9"	"803.2"	"1000.8"	"1165.7"	"828.3"	"888.9"	"1613.6"	"1691.7"	"2678.4"	"6014.7"	"6093.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EE3"	"Nucleoporin SEH1 OS=Homo sapiens OX=9606 GN=SEH1L PE=1 SV=3"	"0.000"	""	"31"	"7"	"20"	"7"	"360"	"39.6"	"8.09"	"3564.55"	"55.08"	"5"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"81929"	"ENSG00000085415"	"SEH1L"	"A8K5B1; hsa:81929; Q8NFU6; Q96EE3; Q96MH3; Q9C069"	""	"Amino acids regulate mTORC1"	"1"	"0"	"291.5"	"321.4"	"327.0"	"470.0"	"294.4"	"259.4"	"498.3"	"537.2"	"667.9"	"1674.9"	"2477.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVA2"	"Septin-11 OS=Homo sapiens OX=9606 GN=SEPTIN11 PE=1 SV=3"	"0.000"	""	"35"	"13"	"27"	"5"	"429"	"49.4"	"6.81"	"4787.52"	"54.89"	"10"	"12"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55752"	"ENSG00000138758"	"SEPTIN11"	"B7Z7Z6; E9KL32; hsa:55752; Q4W5G1; Q7L4N1; Q96SP1; Q9NVA2; Q9UFY9"	"22q11.2 copy number variation syndrome"	""	"1"	"8"	"677.8"	"539.6"	"835.7"	"1150.3"	"680.6"	"635.6"	"1806.5"	"1916.7"	"3023.2"	"6319.1"	"8366.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75475"	"PC4 and SFRS1-interacting protein OS=Homo sapiens OX=9606 GN=PSIP1 PE=1 SV=1"	"0.000"	""	"27"	"12"	"31"	"12"	"530"	"60.1"	"9.13"	"5684.52"	"54.84"	"11"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf11467"	"11168"	"ENSG00000164985"	"PSIP1"	"D3DRI9; hsa:11168; O00256; O75475; O95368; Q6P391; Q86YB9; Q9NZI3; Q9UER6"	"MECP2 and associated Rett syndrome"	"Formation of WDR5-containing histone-modifying complexes; Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection"	"8"	"0"	"1155.2"	"991.0"	"1235.3"	"1216.1"	"1071.1"	"1079.5"	"1721.2"	"1667.0"	"2332.2"	"3657.1"	"3381.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1F7"	"Nuclear pore complex protein Nup93 OS=Homo sapiens OX=9606 GN=NUP93 PE=1 SV=2"	"0.000"	""	"17"	"13"	"31"	"13"	"819"	"93.4"	"5.72"	"5342.59"	"54.66"	"12"	"13"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf04097"	"9688"	"ENSG00000102900"	"NUP93"	"B3KPQ8; hsa:9688; Q14705; Q8N1F7"	""	"SUMOylation of DNA replication proteins; Regulation of HSF1-mediated heat shock response; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Late Events; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"1261.0"	"969.1"	"1332.5"	"1453.8"	"1097.9"	"1135.1"	"1765.8"	"1765.3"	"2225.1"	"4127.8"	"5575.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00291"	"Huntingtin-interacting protein 1 OS=Homo sapiens OX=9606 GN=HIP1 PE=1 SV=5"	"0.000"	""	"16"	"15"	"28"	"15"	"1037"	"116.1"	"5.30"	"5581.60"	"54.59"	"14"	"14"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"3092"	"ENSG00000127946"	"HIP1"	"B4E3I7; E7ES17; hsa:3092; O00291; O00328; Q2TB58; Q8TDL4; V5LU97"	"DYRK1A involvement regarding cell proliferation in brain development; 5q35 copy number variation"	"Clathrin-mediated endocytosis; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants"	"5"	"0"	"265.4"	"243.4"	"410.9"	"440.3"	"331.1"	"335.1"	"1145.2"	"1286.0"	"2394.0"	"6882.8"	"9445.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15366"	"Poly(rC)-binding protein 2 OS=Homo sapiens OX=9606 GN=PCBP2 PE=1 SV=1"	"0.000"	""	"33"	"10"	"24"	"4"	"365"	"38.6"	"6.79"	"4138.56"	"54.53"	"7"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"5094"	"ENSG00000197111"	"PCBP2"	"A8K7X6; B4DXP5; F8VYL7; G3V0E8; hsa:5094; I6L8F9; Q15366; Q32Q82; Q59HD4; Q68Y55; Q6IPF4; Q6PKG5"	"mRNA processing; Ferroptosis; Modulators of TCR signaling and T cell activation"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses"	"7"	"7"	"1003.8"	"939.3"	"1215.7"	"1584.6"	"889.8"	"877.0"	"1650.3"	"1727.7"	"2141.4"	"4445.4"	"6006.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62258"	"14-3-3 protein epsilon OS=Homo sapiens OX=9606 GN=YWHAE PE=1 SV=1"	"0.000"	""	"54"	"12"	"36"	"10"	"255"	"29.2"	"4.74"	"8855.71"	"54.03"	"10"	"10"	"stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7531"	"ENSG00000108953; ENSG00000274474"	"YWHAE"	"B3KY71; D3DTH5; hsa:7531; P29360; P42655; P62258; Q4VJB6; Q53XZ5; Q63631; Q7M4R4"	"Cell cycle; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Calcium regulation in cardiac cells; 17p13.3 (YWHAE) copy number variation; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Regulation of HSF1-mediated heat shock response; TP53 Regulates Metabolic Genes; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria ; RAB GEFs exchange GTP for GDP on RABs; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by Hippo; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; HSF1 activation; NADE modulates death signalling"	"26"	"4"	"1663.3"	"1780.4"	"1588.0"	"1865.7"	"1455.4"	"1519.1"	"2321.3"	"2523.0"	"3005.1"	"5927.8"	"7798.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41252"	"Isoleucine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=IARS1 PE=1 SV=2"	"0.000"	""	"15"	"15"	"33"	"15"	"1262"	"144.4"	"6.15"	"8055.89"	"53.96"	"14"	"13"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf08264, Pf19302"	"3376"	"ENSG00000196305"	"IARS1"	"A8KAE9; hsa:3376; P41252; Q5TCD0; Q7Z3T4; Q9H588"	"Amino acid metabolism"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"706.2"	"619.2"	"812.0"	"981.9"	"666.0"	"697.1"	"1306.1"	"1397.1"	"2248.0"	"7436.8"	"10631.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68431"	"Histone H3.1 OS=Homo sapiens OX=9606 GN=H3C1 PE=1 SV=2"	"0.000"	""	"55"	"8"	"26"	"1"	"136"	"15.4"	"11.12"	"4166.28"	"53.87"	"7"	"8"	"cell organization and biogenesis;other metabolic processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8350; 8351; 8352; 8353; 8354; 8355; 8356; 8357; 8358; 8968"	"ENSG00000197153; ENSG00000197409; ENSG00000273983; ENSG00000274750; ENSG00000275379; ENSG00000275714; ENSG00000277775; ENSG00000278828; ENSG00000286522; ENSG00000287080"	"H3C1; H3C10; H3C11; H3C12; H3C2; H3C3; H3C4; H3C6; H3C7; H3C8"	"A0PJT7; A5PLR1; hsa:8350; hsa:8351; hsa:8352; hsa:8353; hsa:8354; hsa:8355; hsa:8356; hsa:8357; hsa:8358; hsa:8968; P02295; P02296; P16106; P68431; Q6ISV8; Q6NWP8; Q6NWP9; Q6NXU4; Q71DJ3; Q93081"	"Histone modifications; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	"Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Transcriptional regulation of granulopoiesis; Amyloid fiber formation; HCMV Late Events; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Interleukin-7 signaling; RMTs methylate histone arginines; PKMTs methylate histone lysines"	"36"	"11"	"1515.6"	"1208.4"	"1611.4"	"2490.9"	"1131.2"	"1215.6"	"1885.1"	"2081.0"	"2315.2"	"4574.9"	"6685.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12905"	"Interleukin enhancer-binding factor 2 OS=Homo sapiens OX=9606 GN=ILF2 PE=1 SV=2"	"0.000"	""	"31"	"7"	"14"	"7"	"390"	"43.0"	"5.26"	"2644.42"	"53.73"	"4"	"7"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07528"	"3608"	"ENSG00000143621"	"ILF2"	"A6NDB0; B2R8G7; hsa:3608; Q12905; Q5SR10; Q5SR11; Q7L7R3; Q9BWD4; Q9P1N0"	"B cell receptor signaling pathway"	"Neutrophil degranulation"	"2"	"0"	"1410.7"	"1448.5"	"1473.7"	"1792.6"	"1223.3"	"1259.4"	"1865.2"	"1883.3"	"2016.7"	"3469.4"	"4797.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24534"	"Elongation factor 1-beta OS=Homo sapiens OX=9606 GN=EEF1B2 PE=1 SV=3"	"0.000"	""	"72"	"14"	"28"	"12"	"225"	"24.7"	"4.67"	"4481.50"	"53.60"	"11"	"11"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf00736, Pf10587"	"1933"	"ENSG00000114942; ENSG00000283391"	"EEF1B2"	"A8K795; hsa:1933; P24534; Q6IBH9"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"2"	"1743.4"	"1588.9"	"1560.1"	"1868.6"	"1416.6"	"1389.4"	"2272.8"	"2320.2"	"2940.3"	"7116.6"	"9546.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43395"	"U4/U6 small nuclear ribonucleoprotein Prp3 OS=Homo sapiens OX=9606 GN=PRPF3 PE=1 SV=2"	"0.000"	""	"22"	"12"	"26"	"12"	"683"	"77.5"	"9.50"	"5033.44"	"53.44"	"9"	"11"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf01480, Pf06544, Pf08572"	"9129"	"ENSG00000117360"	"PRPF3"	"B4DSY9; hsa:9129; O43395; O43446; Q5VT54"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1202.2"	"1047.3"	"1320.5"	"1481.1"	"1029.9"	"1143.1"	"1577.5"	"1661.7"	"2050.5"	"3778.0"	"5199.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50991"	"T-complex protein 1 subunit delta OS=Homo sapiens OX=9606 GN=CCT4 PE=1 SV=4"	"0.000"	""	"35"	"15"	"26"	"15"	"539"	"57.9"	"7.83"	"5118.56"	"53.19"	"10"	"13"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00118"	"10575"	"ENSG00000115484"	"CCT4"	"B2R6I3; B7Z8B1; F5H5W3; hsa:10575; O14870; P50991; Q53QP9; Q96C51"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"499.6"	"442.4"	"526.5"	"660.4"	"433.4"	"503.5"	"958.5"	"980.2"	"1380.0"	"7513.4"	"15194.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55072"	"Transitional endoplasmic reticulum ATPase OS=Homo sapiens OX=9606 GN=VCP PE=1 SV=4"	"0.000"	""	"25"	"14"	"26"	"14"	"806"	"89.3"	"5.26"	"5185.37"	"52.97"	"11"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf09336, Pf17862"	"7415"	"ENSG00000165280"	"VCP"	"B2R5T8; hsa:7415; P55072; Q0V924; Q2TAI5; Q969G7; Q9UCD5"	"Alstrom syndrome; Clock-controlled autophagy in bone metabolism"	"Neutrophil degranulation; E3 ubiquitin ligases ubiquitinate target proteins; ABC-family proteins mediated transport; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Defective CFTR causes cystic fibrosis; Neddylation; KEAP1-NFE2L2 pathway; Aggrephagy; Attachment and Entry; Attachment and Entry; Ovarian tumor domain proteases; Josephin domain DUBs; Protein methylation; RHOH GTPase cycle; HSF1 activation; Translesion Synthesis by POLH; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"20"	"0"	"1281.9"	"1180.3"	"1242.8"	"1591.7"	"1120.8"	"1101.8"	"1560.5"	"1565.4"	"1749.2"	"2861.4"	"3658.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33991"	"DNA replication licensing factor MCM4 OS=Homo sapiens OX=9606 GN=MCM4 PE=1 SV=5"	"0.000"	""	"20"	"14"	"21"	"14"	"863"	"96.5"	"6.74"	"3073.29"	"52.73"	"8"	"13"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4173"	"ENSG00000104738"	"MCM4"	"hsa:4173; P33991; Q8NEH1; Q99658"	"Cell cycle; Gastric cancer network 1; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"622.4"	"521.5"	"740.3"	"1074.2"	"522.8"	"579.2"	"979.1"	"1005.0"	"1329.2"	"3821.9"	"8517.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AE4"	"Far upstream element-binding protein 1 OS=Homo sapiens OX=9606 GN=FUBP1 PE=1 SV=3"	"0.000"	""	"24"	"16"	"32"	"11"	"644"	"67.5"	"7.61"	"6077.84"	"52.56"	"16"	"14"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013, Pf09005"	"8880"	"ENSG00000162613"	"FUBP1"	"hsa:8880; Q12828; Q96AE4"	""	""	"0"	"2"	"1248.8"	"1232.8"	"1369.4"	"1859.0"	"1238.8"	"1245.0"	"1982.8"	"2016.0"	"2416.8"	"4281.0"	"5989.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT78"	"COP9 signalosome complex subunit 4 OS=Homo sapiens OX=9606 GN=COPS4 PE=1 SV=1"	"0.000"	""	"38"	"12"	"25"	"12"	"406"	"46.2"	"5.83"	"4715.74"	"52.11"	"9"	"12"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18420"	"51138"	"ENSG00000138663"	"COPS4"	"B3KN88; B3KST5; hsa:51138; Q561W7; Q9BT78; Q9NW31; Q9Y677"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; RHOBTB1 GTPase cycle"	"6"	"0"	"250.6"	"222.4"	"279.3"	"364.8"	"250.1"	"278.7"	"746.6"	"863.9"	"1302.5"	"5531.3"	"8359.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54886"	"Delta-1-pyrroline-5-carboxylate synthase OS=Homo sapiens OX=9606 GN=ALDH18A1 PE=1 SV=2"	"0.000"	""	"21"	"14"	"28"	"14"	"795"	"87.2"	"7.12"	"4962.17"	"52.01"	"13"	"14"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00171, Pf00696"	"5832"	"ENSG00000059573"	"ALDH18A1"	"B2R5Q4; B7Z350; B7Z5X8; B7ZLP1; D3DR44; hsa:5832; O95952; P54886; Q3KQU2; Q5T566; Q5T567; Q9UM72"	"Amino acid metabolism"	""	"1"	"0"	"827.9"	"672.2"	"839.8"	"1082.0"	"696.8"	"772.6"	"1208.8"	"1258.1"	"1684.4"	"3998.2"	"5761.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36776"	"Lon protease homolog, mitochondrial OS=Homo sapiens OX=9606 GN=LONP1 PE=1 SV=2"	"0.000"	""	"14"	"13"	"24"	"13"	"959"	"106.4"	"6.39"	"3799.35"	"51.81"	"8"	"13"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf02190, Pf05362"	"9361"	"ENSG00000196365"	"LONP1"	"B3KPH8; D6W635; E5KMH8; F5GZ27; hsa:9361; P36776; P36777; Q8N8K8; Q9UQ95"	""	""	"0"	"0"	"233.3"	"200.8"	"281.6"	"360.5"	"231.0"	"235.3"	"590.4"	"626.0"	"1072.9"	"7378.0"	"9999.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15042"	"U2 snRNP-associated SURP motif-containing protein OS=Homo sapiens OX=9606 GN=U2SURP PE=1 SV=2"	"0.000"	""	"17"	"15"	"32"	"14"	"1029"	"118.2"	"8.47"	"6026.16"	"51.66"	"15"	"14"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076, Pf01805, Pf04818, Pf08312"	"23350"	"ENSG00000163714"	"U2SURP"	"A0PJ60; hsa:23350; O15042; Q0D2M1; Q2NKQ7; Q9BR70"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"1848.6"	"1650.2"	"2074.0"	"2550.6"	"1778.3"	"1856.4"	"2490.3"	"2540.9"	"3016.4"	"6714.7"	"9498.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27695"	"DNA-(apurinic or apyrimidinic site) lyase OS=Homo sapiens OX=9606 GN=APEX1 PE=1 SV=2"	"0.000"	""	"44"	"12"	"25"	"12"	"318"	"35.5"	"8.12"	"6174.16"	"51.52"	"11"	"10"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372"	"328"	"ENSG00000100823"	"APEX1"	"hsa:328; P27695; Q969L5; Q99775"	"Thyroid stimulating hormone (TSH) signaling pathway; Spinal cord injury; Base excision repair; DNA repair pathways, full network"	"Displacement of DNA glycosylase by APEX1; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"775.9"	"772.3"	"767.2"	"866.3"	"703.5"	"696.8"	"1774.6"	"2003.1"	"3187.9"	"6067.8"	"5299.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ29"	"Putative RNA-binding protein Luc7-like 1 OS=Homo sapiens OX=9606 GN=LUC7L PE=1 SV=1"	"0.000"	""	"23"	"9"	"27"	"5"	"371"	"43.7"	"9.92"	"5157.98"	"51.33"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03194"	"55692"	"ENSG00000007392"	"LUC7L"	"B8ZZ13; hsa:55692; Q96S32; Q9NPH4; Q9NQ29"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"241.4"	"246.1"	"319.7"	"384.4"	"246.4"	"261.4"	"479.9"	"488.6"	"745.2"	"1726.1"	"2291.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCS8"	"Polyribonucleotide nucleotidyltransferase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PNPT1 PE=1 SV=2"	"0.000"	""	"19"	"11"	"26"	"11"	"783"	"85.9"	"7.77"	"5402.26"	"51.21"	"10"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf01138, Pf03725, Pf03726"	"87178"	"ENSG00000138035"	"PNPT1"	"hsa:87178; Q53SU0; Q68CN1; Q7Z7D1; Q8IWX1; Q8TCS8; Q96T05; Q9BRU3; Q9BVX0"	"Pyrimidine metabolism; miRNA degrading enzymes"	""	"2"	"0"	"706.9"	"636.6"	"794.9"	"921.9"	"611.4"	"638.9"	"1185.4"	"1184.3"	"1812.9"	"4693.6"	"6160.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14157"	"Ubiquitin-associated protein 2-like OS=Homo sapiens OX=9606 GN=UBAP2L PE=1 SV=2"	"0.000"	""	"13"	"9"	"19"	"9"	"1087"	"114.5"	"7.11"	"3350.67"	"50.93"	"7"	"9"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf12478"	"9898"	"ENSG00000143569"	"UBAP2L"	"B4E0U8; hsa:9898; Q14157; Q5VU75; Q5VU76; Q9BTU3; Q9UGL2; Q9UGL3; Q9UGL4; Q9UGL5"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"998.7"	"921.0"	"1084.3"	"1298.3"	"920.7"	"1002.6"	"1354.7"	"1382.0"	"1614.7"	"3109.3"	"4075.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49756"	"RNA-binding protein 25 OS=Homo sapiens OX=9606 GN=RBM25 PE=1 SV=3"	"0.000"	""	"18"	"12"	"26"	"12"	"843"	"100.1"	"6.32"	"5315.45"	"50.81"	"11"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf01480"	"58517"	"ENSG00000119707"	"RBM25"	"A0PJL9; B2RNA8; B3KT03; hsa:58517; P49756; Q2TA72; Q5XJ17; Q6P665; Q9H6A1; Q9UEQ5; Q9UIE9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"913.2"	"805.3"	"880.3"	"957.5"	"710.5"	"793.1"	"1238.4"	"1291.4"	"1825.2"	"5231.8"	"7188.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55196"	"Afadin OS=Homo sapiens OX=9606 GN=AFDN PE=1 SV=3"	"0.000"	""	"8"	"12"	"26"	"12"	"1824"	"206.7"	"6.47"	"4887.40"	"50.81"	"10"	"10"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00498, Pf00595, Pf00788, Pf01843"	"4301"	"ENSG00000130396"	"AFDN"	"hsa:4301; O75087; O75088; O75089; P55196; Q59FP0; Q5TIG6; Q5TIG7; Q9NSN7; Q9NU92"	"VEGFA-VEGFR2 signaling; Ras signaling; 1q21.1 copy number variation syndrome"	""	"3"	"0"	"777.5"	"659.8"	"823.0"	"914.6"	"654.0"	"645.5"	"1510.9"	"1541.6"	"2600.8"	"4046.7"	"3854.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0D6"	"5'-3' exoribonuclease 2 OS=Homo sapiens OX=9606 GN=XRN2 PE=1 SV=1"	"0.000"	""	"22"	"13"	"25"	"13"	"950"	"108.5"	"7.47"	"5118.75"	"50.74"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846"	"22803"	"ENSG00000088930"	"XRN2"	"hsa:22803; Q3L8N4; Q6KGZ9; Q9BQL1; Q9H0D6; Q9NTW0; Q9NXS6; Q9UL53"	"mRNA processing"	"Major pathway of rRNA processing in the nucleolus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"3"	"0"	"982.6"	"795.8"	"1162.8"	"1587.9"	"939.1"	"938.6"	"1595.4"	"1646.9"	"2097.6"	"4439.8"	"6326.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61604"	"10 kDa heat shock protein, mitochondrial OS=Homo sapiens OX=9606 GN=HSPE1 PE=1 SV=2"	"0.000"	""	"80"	"12"	"27"	"12"	"102"	"10.9"	"8.92"	"6317.88"	"50.71"	"11"	"9"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf00166"	"3336"	"ENSG00000115541"	"HSPE1"	"hsa:3336; O95421; P61604; Q04984; Q53X54; Q9UDH0"	""	"RHOG GTPase cycle"	"1"	"0"	"430.4"	"365.0"	"512.2"	"617.4"	"459.3"	"859.8"	"3586.4"	"4175.6"	"5235.8"	"11514.4"	"16304.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSJ8"	"Extended synaptotagmin-1 OS=Homo sapiens OX=9606 GN=ESYT1 PE=1 SV=1"	"0.000"	""	"17"	"12"	"20"	"12"	"1104"	"122.8"	"5.83"	"3312.47"	"50.59"	"7"	"11"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00168, Pf17047"	"23344"	"ENSG00000139641"	"ESYT1"	"A0FGR7; A8K2S2; hsa:23344; O94848; Q6PJN4; Q9BSJ8; Q9H6J1; Q9H6W2; Q9Y416"	""	"RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Glycosphingolipid metabolism; RHOF GTPase cycle"	"7"	"0"	"189.6"	"178.3"	"572.8"	"371.8"	"368.3"	"589.0"	"1540.9"	"1564.9"	"2006.8"	"3754.9"	"4768.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13523"	"Serine/threonine-protein kinase PRP4 homolog OS=Homo sapiens OX=9606 GN=PRPF4B PE=1 SV=3"	"0.000"	""	"13"	"12"	"29"	"11"	"1007"	"116.9"	"10.26"	"5324.50"	"50.31"	"10"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8899"	"ENSG00000112739"	"PRPF4B"	"A8K5C9; hsa:8899; Q13523; Q5D0F6; Q5TAY8; Q8IVC3; Q8TDP2; Q96QT7; Q9UEE6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"1363.9"	"1251.5"	"1727.8"	"2046.4"	"1258.7"	"1325.1"	"2176.4"	"2171.7"	"3018.0"	"6971.7"	"8756.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16152"	"Carbonyl reductase [NADPH] 1 OS=Homo sapiens OX=9606 GN=CBR1 PE=1 SV=3"	"0.000"	""	"42"	"10"	"24"	"10"	"277"	"30.4"	"8.32"	"4803.24"	"50.13"	"9"	"10"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00106"	"873"	"ENSG00000159228"	"CBR1"	"B2RBZ7; B4DFK7; hsa:873; P16152; Q3LHW8"	"Nuclear receptors meta-pathway; NRF2 pathway; Prostaglandin synthesis and regulation"	"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)"	"4"	"0"	"255.2"	"206.7"	"322.4"	"386.9"	"262.7"	"272.0"	"769.7"	"843.6"	"1411.4"	"4705.9"	"7339.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49368"	"T-complex protein 1 subunit gamma OS=Homo sapiens OX=9606 GN=CCT3 PE=1 SV=4"	"0.000"	""	"33"	"15"	"25"	"15"	"545"	"60.5"	"6.49"	"4042.23"	"49.81"	"11"	"12"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00118"	"7203"	"ENSG00000163468"	"CCT3"	"A6NE14; hsa:7203; P49368; Q5SZY1; Q9BR64"	"16p11.2 proximal deletion syndrome"	"Formation of tubulin folding intermediates by CCT/TriC; BBSome-mediated cargo-targeting to cilium; Association of TriC/CCT with target proteins during biosynthesis; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; Prefoldin mediated transfer of substrate  to CCT/TriC; Folding of actin by CCT/TriC"	"7"	"0"	"445.0"	"380.7"	"545.4"	"667.9"	"428.1"	"447.3"	"873.1"	"935.2"	"1273.0"	"6150.3"	"11932.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94906"	"Pre-mRNA-processing factor 6 OS=Homo sapiens OX=9606 GN=PRPF6 PE=1 SV=1"	"0.000"	""	"16"	"13"	"24"	"13"	"941"	"106.9"	"8.25"	"3194.89"	"49.76"	"10"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06424, Pf13181"	"24148"	"ENSG00000101161"	"PRPF6"	"B2RAR5; B3KMC6; hsa:24148; O94906; O95109; Q5VXS5; Q9H3Z1; Q9H4T9; Q9H4U8; Q9NTE6"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"618.9"	"581.8"	"771.2"	"907.6"	"596.6"	"631.9"	"1002.7"	"1122.6"	"1387.6"	"4064.6"	"5948.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15428"	"Splicing factor 3A subunit 2 OS=Homo sapiens OX=9606 GN=SF3A2 PE=1 SV=2"	"0.000"	""	"15"	"7"	"21"	"7"	"464"	"49.2"	"9.64"	"4211.44"	"49.75"	"5"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf12874, Pf16835"	"8175"	"ENSG00000104897"	"SF3A2"	"B2RBU1; D6W605; hsa:8175; O75245; Q15428"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"509.4"	"452.3"	"514.1"	"678.2"	"479.5"	"490.4"	"912.2"	"955.5"	"1470.6"	"5454.9"	"8324.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW27"	"Nuclear pore complex protein Nup85 OS=Homo sapiens OX=9606 GN=NUP85 PE=1 SV=1"	"0.000"	""	"19"	"10"	"22"	"10"	"656"	"75.0"	"5.55"	"3991.21"	"49.63"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07575"	"79902"	"ENSG00000125450"	"NUP85"	"B4DMQ3; B4DPW1; hsa:79902; Q8NDI4; Q9BW27; Q9H9U1"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SARS-CoV-2 activates/modulates innate and adaptive immune responses; tRNA processing in the nucleus; Viral Messenger RNA Synthesis; SUMOylation of DNA damage response and repair proteins; Rev-mediated nuclear export of HIV RNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"495.5"	"507.8"	"575.0"	"821.5"	"454.6"	"438.0"	"904.1"	"999.1"	"1253.1"	"2690.7"	"3483.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43243"	"Matrin-3 OS=Homo sapiens OX=9606 GN=MATR3 PE=1 SV=2"	"0.000"	""	"19"	"19"	"33"	"19"	"847"	"94.6"	"6.25"	"6589.35"	"49.53"	"17"	"12"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	""	"9782"	"ENSG00000015479"	"MATR3"	"B7ZAV5; D3DQC3; hsa:9782; P43243; Q9UHW0; Q9UQ27"	""	""	"0"	"0"	"1503.7"	"1470.5"	"1729.5"	"2366.0"	"1374.9"	"1387.8"	"2266.3"	"2372.4"	"2648.9"	"5541.1"	"7491.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N684"	"Cleavage and polyadenylation specificity factor subunit 7 OS=Homo sapiens OX=9606 GN=CPSF7 PE=1 SV=1"	"0.000"	""	"23"	"10"	"24"	"10"	"471"	"52.0"	"8.00"	"4938.57"	"49.28"	"9"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79869"	"ENSG00000149532"	"CPSF7"	"B3KU04; C9K0Q4; hsa:79869; Q7Z3H9; Q8N684; Q9H025; Q9H9V1"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; RHOBTB1 GTPase cycle"	"5"	"0"	"831.3"	"809.3"	"838.5"	"1117.4"	"742.2"	"704.1"	"1291.5"	"1305.1"	"1631.5"	"3429.6"	"4832.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16181"	"Septin-7 OS=Homo sapiens OX=9606 GN=SEPTIN7 PE=1 SV=2"	"0.000"	""	"27"	"10"	"27"	"9"	"437"	"50.6"	"8.63"	"6119.57"	"49.19"	"10"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00735"	"989"	"ENSG00000122545"	"SEPTIN7"	"hsa:989; Q16181; Q52M76; Q6NX50"	""	"MAPK6/MAPK4 signaling"	"1"	"0"	"609.6"	"551.4"	"758.5"	"826.3"	"629.3"	"611.2"	"1113.2"	"1148.5"	"1497.1"	"2788.9"	"3794.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PK6"	"RNA-binding protein 14 OS=Homo sapiens OX=9606 GN=RBM14 PE=1 SV=2"	"0.000"	""	"23"	"14"	"31"	"14"	"669"	"69.4"	"9.67"	"5990.58"	"49.00"	"13"	"13"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076"	"100526737; 10432"	"ENSG00000239306"	"RBM14"	"B0LM41; B3KMN4; D6RGD8; hsa:100526737; hsa:10432; O75932; Q2PYN1; Q53GV1; Q68DQ9; Q96PK5; Q96PK6"	"Ciliary landscape"	"RUNX2 regulates bone development"	"2"	"0"	"1167.4"	"1242.6"	"1270.2"	"1596.9"	"1166.3"	"1122.9"	"1750.4"	"1837.5"	"2134.7"	"4194.5"	"5791.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14678"	"Small nuclear ribonucleoprotein-associated proteins B and B' OS=Homo sapiens OX=9606 GN=SNRPB PE=1 SV=2"	"0.000"	""	"22"	"7"	"19"	"7"	"240"	"24.6"	"11.19"	"1989.87"	"48.86"	"4"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6628"	"ENSG00000125835"	"SNRPB"	"hsa:6628; P14678; Q15490; Q6IB35; Q9UIS5"	"mRNA processing"	"snRNP Assembly; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"714.5"	"511.2"	"829.8"	"1111.4"	"621.1"	"572.2"	"986.0"	"947.4"	"1078.9"	"2155.7"	"3358.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14498"	"RNA-binding protein 39 OS=Homo sapiens OX=9606 GN=RBM39 PE=1 SV=2"	"0.000"	""	"20"	"9"	"24"	"8"	"530"	"59.3"	"10.10"	"3198.54"	"48.79"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf15519"	"9584"	"ENSG00000131051"	"RBM39"	"A2RRD3; A5D8W2; B0BLV3; E1P5S0; E1P5S1; hsa:9584; Q14498; Q14499"	"VEGFA-VEGFR2 signaling; mRNA processing"	"mRNA Splicing - Major Pathway"	"3"	"1"	"995.1"	"885.4"	"1063.5"	"1140.2"	"866.8"	"880.4"	"1284.0"	"1355.6"	"1769.7"	"3550.8"	"4543.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXJ9"	"N-alpha-acetyltransferase 15, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA15 PE=1 SV=1"	"0.000"	""	"18"	"17"	"28"	"15"	"866"	"101.2"	"7.42"	"4004.98"	"48.65"	"11"	"15"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf12569, Pf13181"	"80155"	"ENSG00000164134"	"NAA15"	"D3DNY6; hsa:80155; Q52LG9; Q8IWH4; Q8NEV2; Q9BXJ9; Q9H8P6"	""	""	"0"	"2"	"479.3"	"416.3"	"549.0"	"690.6"	"455.3"	"467.0"	"1069.2"	"1068.8"	"1689.5"	"9589.3"	"13274.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92499"	"ATP-dependent RNA helicase DDX1 OS=Homo sapiens OX=9606 GN=DDX1 PE=1 SV=2"	"0.000"	""	"19"	"10"	"22"	"10"	"740"	"82.4"	"7.23"	"4634.46"	"48.61"	"10"	"10"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00622"	"1653"	"ENSG00000079785"	"DDX1"	"B4DME8; B4DPN6; hsa:1653; Q92499"	"DDX1 as a regulatory component of the Drosha microprocessor; mRNA processing"	"tRNA processing in the nucleus"	"3"	"0"	"616.7"	"605.2"	"704.6"	"877.1"	"646.5"	"641.9"	"1011.5"	"1003.8"	"1225.0"	"2631.2"	"4308.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82979"	"SAP domain-containing ribonucleoprotein OS=Homo sapiens OX=9606 GN=SARNP PE=1 SV=3"	"0.000"	""	"31"	"9"	"26"	"9"	"210"	"23.7"	"6.42"	"5994.49"	"48.60"	"9"	"9"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037"	"84324"	"ENSG00000205323"	"SARNP"	"A8K393; hsa:84324; P82979; Q9P066"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"1036.6"	"1038.6"	"1044.0"	"1291.0"	"948.6"	"990.3"	"2494.6"	"2744.2"	"4696.4"	"8404.7"	"7762.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42166"	"Lamina-associated polypeptide 2, isoform alpha OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"0.000"	""	"22"	"11"	"18"	"4"	"694"	"75.4"	"7.66"	"2970.31"	"48.52"	"7"	"10"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198, Pf11560"	"7112"	"ENSG00000120802"	"TMPO"	"P08918; P08919; P42166; Q14860; Q16295"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	""	"2"	"0"	"328.1"	"355.4"	"300.5"	"325.4"	"283.7"	"287.2"	"564.1"	"626.3"	"922.5"	"1660.9"	"1792.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11310"	"Medium-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADM PE=1 SV=1"	"0.000"	""	"32"	"9"	"17"	"9"	"421"	"46.6"	"8.37"	"3237.47"	"48.02"	"6"	"9"	"other metabolic processes;stress response;developmental processes;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"34"	"ENSG00000117054"	"ACADM"	"hsa:34; P11310; Q5T4U4; Q9NYF1"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; PPAR signaling pathway; Mitochondrial fatty acid oxidation disorders; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"PPARA activates gene expression; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA"	"13"	"0"	"300.7"	"272.2"	"364.1"	"423.5"	"281.3"	"284.8"	"608.9"	"674.9"	"1091.4"	"4285.5"	"6629.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75934"	"Pre-mRNA-splicing factor SPF27 OS=Homo sapiens OX=9606 GN=BCAS2 PE=1 SV=1"	"0.000"	""	"41"	"9"	"22"	"9"	"225"	"26.1"	"5.66"	"4087.45"	"48.02"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05700"	"10286"	"ENSG00000116752"	"BCAS2"	"hsa:10286; O75934; Q6FGS0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"230.1"	"183.9"	"293.4"	"350.6"	"221.1"	"239.1"	"701.3"	"764.9"	"1271.8"	"4270.8"	"5462.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56192"	"Methionine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=MARS1 PE=1 SV=2"	"0.000"	""	"18"	"10"	"18"	"10"	"900"	"101.1"	"6.16"	"2951.62"	"47.97"	"7"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00043, Pf00458, Pf09334, Pf18485, Pf19303"	"4141"	"ENSG00000166986"	"MARS1"	"B3KVK7; hsa:4141; P56192; Q14895; Q53H14; Q96A15; Q96BZ0; Q9NSE0"	""	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"2"	"0"	"479.9"	"425.4"	"553.3"	"644.0"	"427.2"	"388.6"	"803.3"	"902.9"	"1314.0"	"4370.2"	"5994.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR30"	"Nucleolar RNA helicase 2 OS=Homo sapiens OX=9606 GN=DDX21 PE=1 SV=5"	"0.000"	""	"15"	"10"	"26"	"9"	"783"	"87.3"	"9.28"	"5663.89"	"47.59"	"10"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf08152"	"9188"	"ENSG00000165732"	"DDX21"	"B2RDL0; hsa:9188; Q13436; Q5VX41; Q68D35; Q9NR30"	"10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Major pathway of rRNA processing in the nucleolus and cytosol"	"3"	"1"	"892.5"	"741.6"	"1008.1"	"1224.0"	"859.4"	"929.0"	"1679.5"	"1703.5"	"2540.5"	"5381.5"	"7649.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62136"	"Serine/threonine-protein phosphatase PP1-alpha catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CA PE=1 SV=1"	"0.000"	""	"35"	"10"	"23"	"3"	"330"	"37.5"	"6.33"	"4519.86"	"47.58"	"9"	"10"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5499"	"ENSG00000172531"	"PPP1CA"	"A6NNR3; B2R908; hsa:5499; P08129; P20653; P22802; P62136; Q07161"	"Sphingolipid pathway; Nicotine effect on dopaminergic neurons; Common pathways underlying drug addiction; Focal adhesion; VEGFA-VEGFR2 signaling; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Netrin-UNC5B signaling pathway; Neuroinflammation and glutamatergic signaling"	"Triglyceride catabolism; Circadian Clock; Downregulation of TGF-beta receptor signaling; DARPP-32 events"	"13"	"7"	"527.7"	"516.5"	"638.7"	"642.3"	"466.3"	"468.6"	"969.2"	"1009.7"	"1415.1"	"3858.6"	"5173.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EK5"	"KIF-binding protein OS=Homo sapiens OX=9606 GN=KIFBP PE=1 SV=1"	"0.000"	""	"23"	"13"	"25"	"13"	"621"	"71.8"	"5.49"	"5417.68"	"47.56"	"12"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes"	"cytoskeleton;mitochondrion"	"cytoskeletal activity"	"Pf12309"	"26128"	"ENSG00000198954"	"KIFBP"	"A8K5M8; hsa:26128; Q96EK5; Q9BR89; Q9ULE1; Q9Y428"	""	""	"0"	"0"	"259.6"	"209.1"	"295.2"	"354.5"	"265.2"	"376.5"	"2332.2"	"2691.8"	"4764.9"	"6827.1"	"5041.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZZ5"	"Apoptosis inhibitor 5 OS=Homo sapiens OX=9606 GN=API5 PE=1 SV=3"	"0.000"	""	"31"	"15"	"26"	"15"	"524"	"59.0"	"7.34"	"5833.37"	"47.17"	"14"	"12"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05918"	"8539"	"ENSG00000166181"	"API5"	"B4DGR0; B4DRJ2; B4E283; D3DR21; G3V1C3; hsa:8539; O15441; Q9BZZ5; Q9Y4J7"	""	""	"0"	"0"	"883.1"	"816.9"	"865.7"	"1031.4"	"846.5"	"828.7"	"1388.6"	"1482.7"	"1895.8"	"5196.4"	"8090.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14715"	"RANBP2-like and GRIP domain-containing protein 8 OS=Homo sapiens OX=9606 GN=RGPD8 PE=1 SV=2"	"0.000"	""	"9"	"11"	"19"	"1"	"1765"	"198.9"	"6.49"	"2399.29"	"47.14"	"7"	"11"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf00638, Pf01465, Pf16704"	"727851"	"ENSG00000169629"	"RGPD8"	"hsa:727851; O14715; Q5CZA8"	"2q13 copy number variation syndrome"	""	"1"	"0"	"8.8"	"8.7"	"11.8"	"14.3"	"11.7"	"12.2"	"17.7"	"19.9"	"26.0"	"63.8"	"85.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35240"	"Merlin OS=Homo sapiens OX=9606 GN=NF2 PE=1 SV=1"	"0.000"	""	"27"	"16"	"29"	"15"	"595"	"69.6"	"6.47"	"5759.50"	"47.04"	"15"	"12"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4771"	"ENSG00000186575"	"NF2"	"hsa:4771; O95683; P35240; Q8WUJ2; Q969N0; Q969Q3; Q96T30; Q96T31; Q96T32; Q96T33; Q9BTW3; Q9UNG9; Q9UNH3; Q9UNH4"	"Ectoderm differentiation; Ectoderm differentiation; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; 3q29 copy number variation syndrome; Pleural mesothelioma"	"Regulation of actin dynamics for phagocytic cup formation; RHO GTPases activate PAKs"	"10"	"1"	"1549.7"	"1248.8"	"1653.7"	"2130.2"	"1351.9"	"1379.1"	"2815.0"	"3004.4"	"4922.8"	"6939.4"	"6103.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31946"	"14-3-3 protein beta/alpha OS=Homo sapiens OX=9606 GN=YWHAB PE=1 SV=3"	"0.000"	""	"44"	"10"	"29"	"5"	"246"	"28.1"	"4.83"	"5363.83"	"47.01"	"10"	"9"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00244"	"7529"	"ENSG00000166913"	"YWHAB"	"A8K9K2; E1P616; hsa:7529; P31946"	"Cell cycle; IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Hepatitis B infection; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; mTORC1-mediated signalling; TP53 Regulates Metabolic Genes; Signaling by Hippo; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Rap1 signalling; Negative regulation of MAPK pathway; Frs2-mediated activation; ARMS-mediated activation; Activation of BAD and translocation to mitochondria ; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"33"	"3"	"953.5"	"911.6"	"961.8"	"1177.5"	"852.6"	"874.7"	"1328.2"	"1386.7"	"1627.2"	"2792.7"	"3426.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92922"	"SWI/SNF complex subunit SMARCC1 OS=Homo sapiens OX=9606 GN=SMARCC1 PE=1 SV=3"	"0.000"	""	"14"	"11"	"24"	"10"	"1105"	"122.8"	"5.76"	"4439.33"	"46.99"	"9"	"11"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6599"	"ENSG00000173473"	"SMARCC1"	"hsa:6599; Q17RS0; Q6P172; Q8IWH2; Q92922"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"1"	"885.8"	"745.7"	"985.3"	"1146.0"	"802.9"	"827.5"	"1298.2"	"1349.4"	"1690.3"	"3440.1"	"4334.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62318"	"Small nuclear ribonucleoprotein Sm D3 OS=Homo sapiens OX=9606 GN=SNRPD3 PE=1 SV=1"	"0.000"	""	"55"	"6"	"20"	"6"	"126"	"13.9"	"10.32"	"3497.03"	"46.92"	"4"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"6634"	"ENSG00000100028"	"SNRPD3"	"B4DJP7; B5BU13; hsa:6634; P43331; P62318"	"mRNA processing"	"mRNA Splicing - Major Pathway; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"1450.2"	"1699.7"	"1896.6"	"2307.6"	"1374.6"	"1325.4"	"2070.7"	"2027.3"	"2068.0"	"3832.5"	"5396.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEY8"	"Gamma-adducin OS=Homo sapiens OX=9606 GN=ADD3 PE=1 SV=1"	"0.000"	""	"19"	"12"	"20"	"11"	"706"	"79.1"	"6.32"	"2811.58"	"46.78"	"6"	"11"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"120"	"ENSG00000148700"	"ADD3"	"D3DRA8; hsa:120; O43243; Q5VU09; Q92773; Q9UEY7; Q9UEY8"	""	"Miscellaneous transport and binding events; RHOD GTPase cycle; RHOF GTPase cycle"	"3"	"0"	"464.8"	"416.5"	"461.0"	"575.7"	"412.7"	"463.4"	"872.4"	"999.7"	"1583.1"	"2684.2"	"2771.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BP3"	"Peptidylprolyl isomerase domain and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=PPWD1 PE=1 SV=1"	"0.000"	""	"24"	"11"	"20"	"11"	"646"	"73.5"	"7.15"	"3195.78"	"46.75"	"7"	"11"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160, Pf00400"	"23398"	"ENSG00000113593"	"PPWD1"	"B4DWR9; hsa:23398; Q15002; Q7KZ89; Q96BP3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"507.3"	"451.0"	"540.4"	"669.8"	"470.7"	"512.4"	"956.8"	"1042.1"	"1484.7"	"5756.5"	"8064.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63104"	"14-3-3 protein zeta/delta OS=Homo sapiens OX=9606 GN=YWHAZ PE=1 SV=1"	"0.000"	""	"40"	"9"	"27"	"7"	"245"	"27.7"	"4.79"	"5272.73"	"46.60"	"9"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00244"	"7534"	"ENSG00000164924"	"YWHAZ"	"A8K1N0; B7Z465; hsa:7534; P29213; P29312; P63104; Q32P43; Q5XJ08; Q6GPI2; Q6IN74; Q6NUR9; Q6P3U9; Q86V33"	"Cell cycle; Prolactin signaling pathway; Pathogenic Escherichia coli infection; Myometrial relaxation and contraction pathways; Hepatitis B infection; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Negative regulation of NOTCH4 signaling; Deactivation of the beta-catenin transactivating complex; Interleukin-3, Interleukin-5 and GM-CSF signaling; TP53 Regulates Metabolic Genes; NOTCH4 Activation and Transmission of Signal to the Nucleus; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Rap1 signalling; KSRP (KHSRP) binds and destabilizes mRNA; GP1b-IX-V activation signalling; Activation of BAD and translocation to mitochondria"	"23"	"0"	"735.3"	"737.0"	"755.0"	"994.4"	"693.4"	"728.2"	"1110.8"	"1204.8"	"1440.9"	"2480.1"	"3144.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14566"	"DNA replication licensing factor MCM6 OS=Homo sapiens OX=9606 GN=MCM6 PE=1 SV=1"	"0.000"	""	"17"	"11"	"25"	"11"	"821"	"92.8"	"5.41"	"4182.48"	"46.57"	"9"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855, Pf18263"	"4175"	"ENSG00000076003"	"MCM6"	"B2R6H2; hsa:4175; Q13504; Q14566; Q99859"	"Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"413.5"	"353.7"	"482.6"	"690.2"	"377.8"	"362.6"	"676.0"	"687.7"	"826.5"	"2738.1"	"6246.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15056"	"Eukaryotic translation initiation factor 4H OS=Homo sapiens OX=9606 GN=EIF4H PE=1 SV=5"	"0.000"	""	"46"	"8"	"18"	"8"	"248"	"27.4"	"7.23"	"2934.68"	"46.43"	"5"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7458"	"ENSG00000106682"	"EIF4H"	"A8K3R1; D3DXF6; D3DXF8; hsa:7458; Q15056"	"Translation factors; 7q11.23 copy number variation syndrome"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"7"	"0"	"250.6"	"240.8"	"306.8"	"383.9"	"259.8"	"238.7"	"597.4"	"642.2"	"968.2"	"3205.1"	"4192.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10570"	"Cleavage and polyadenylation specificity factor subunit 1 OS=Homo sapiens OX=9606 GN=CPSF1 PE=1 SV=2"	"0.000"	""	"11"	"13"	"26"	"13"	"1443"	"160.8"	"6.40"	"4453.49"	"46.38"	"12"	"13"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"29894"	"ENSG00000071894; ENSG00000285049"	"CPSF1"	"hsa:29894; Q10570; Q96AF0"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"7"	"0"	"963.4"	"880.1"	"1017.7"	"1208.6"	"910.8"	"869.4"	"1500.8"	"1567.5"	"1922.6"	"5196.2"	"6825.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61158"	"Actin-related protein 3 OS=Homo sapiens OX=9606 GN=ACTR3 PE=1 SV=3"	"0.000"	""	"32"	"10"	"22"	"10"	"418"	"47.3"	"5.88"	"3881.17"	"46.29"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10096"	"ENSG00000115091"	"ACTR3"	"hsa:10096; P32391; P61158; Q53QM2"	"Physico-chemical features and toxicity-associated pathways"	"EPHB-mediated forward signaling; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis"	"6"	"0"	"486.3"	"496.4"	"497.7"	"641.7"	"513.9"	"598.6"	"1408.4"	"1574.9"	"2394.3"	"5081.6"	"5995.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63279"	"SUMO-conjugating enzyme UBC9 OS=Homo sapiens OX=9606 GN=UBE2I PE=1 SV=1"	"0.000"	""	"58"	"10"	"24"	"10"	"158"	"18.0"	"8.66"	"6083.68"	"46.26"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7329"	"ENSG00000103275"	"UBE2I"	"D3DU69; hsa:7329; P50550; P63279; Q15698; Q59GX1; Q86VB3"	"Androgen receptor signaling pathway; TAR syndrome"	"SUMOylation of RNA binding proteins; Meiotic synapsis; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; Formation of Incision Complex in GG-NER; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of DNA replication proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; SUMOylation of intracellular receptors; Vitamin D (calciferol) metabolism; SUMOylation of transcription factors; Postmitotic nuclear pore complex (NPC) reformation; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; Maturation of nucleoprotein; SUMOylation of immune response proteins; SUMOylation of nuclear envelope proteins; Maturation of nucleoprotein; SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"25"	"0"	"978.6"	"893.2"	"1088.0"	"1399.5"	"1042.6"	"1018.5"	"2460.5"	"2716.1"	"3703.5"	"8303.0"	"11064.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15293"	"Reticulocalbin-1 OS=Homo sapiens OX=9606 GN=RCN1 PE=1 SV=1"	"0.000"	""	"39"	"10"	"21"	"10"	"331"	"38.9"	"5.00"	"4529.49"	"45.91"	"8"	"9"	"developmental processes"	"ER/Golgi"	"other molecular function"	"Pf13202"	"5954"	"ENSG00000049449"	"RCN1"	"B7Z1M1; D3DR00; hsa:5954; Q15293"	"VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"3"	"0"	"1379.1"	"1501.3"	"1372.3"	"1530.7"	"1268.6"	"1238.8"	"1639.4"	"1644.1"	"1672.6"	"2215.0"	"2478.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62805"	"Histone H4 OS=Homo sapiens OX=9606 GN=H4C1 PE=1 SV=2"	"0.000"	""	"60"	"10"	"23"	"10"	"103"	"11.4"	"11.36"	"4647.41"	"45.90"	"9"	"9"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511"	"121504; 554313; 8294; 8359; 8360; 8361; 8362; 8363; 8364; 8365; 8366; 8367; 8368; 8370"	"ENSG00000158406; ENSG00000197061; ENSG00000197238; ENSG00000197837; ENSG00000270276; ENSG00000270882; ENSG00000273542; ENSG00000274618; ENSG00000275126; ENSG00000276180; ENSG00000276966; ENSG00000277157; ENSG00000278637; ENSG00000278705"	"H4C1; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9"	"A2VCL0; hsa:121504; hsa:554313; hsa:8294; hsa:8359; hsa:8360; hsa:8361; hsa:8362; hsa:8363; hsa:8364; hsa:8365; hsa:8366; hsa:8367; hsa:8368; hsa:8370; P02304; P02305; P62805; Q6DRA9; Q6FGB8; Q6NWP7"	"Gastric cancer network 1; Histone modifications; 22q11.2 copy number variation syndrome; Male infertility; Type II interferon signaling"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Late Events; HCMV Early Events; SUMOylation of chromatin organization proteins; Transcriptional regulation by small RNAs; Amyloid fiber formation; Meiotic synapsis; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RMTs methylate histone arginines; HDMs demethylate histones; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"50"	"0"	"657.0"	"845.2"	"632.1"	"928.0"	"542.2"	"634.2"	"926.1"	"1025.7"	"1400.5"	"3661.3"	"4495.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q29RF7"	"Sister chromatid cohesion protein PDS5 homolog A OS=Homo sapiens OX=9606 GN=PDS5A PE=1 SV=1"	"0.000"	""	"8"	"10"	"19"	"7"	"1337"	"150.7"	"7.91"	"3210.05"	"45.88"	"7"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf20168"	"23244"	"ENSG00000121892"	"PDS5A"	"hsa:23244; Q29RF7; Q2TTR5; Q68DF7; Q8N7J4; Q8NG14; Q9Y4D4"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"2"	"460.0"	"447.8"	"512.5"	"579.3"	"434.8"	"456.3"	"772.0"	"855.4"	"1226.6"	"2764.6"	"3382.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84243"	"Histone H3.3 OS=Homo sapiens OX=9606 GN=H3-3A PE=1 SV=2"	"0.000"	""	"55"	"8"	"25"	"1"	"136"	"15.3"	"11.27"	"4166.28"	"45.87"	"7"	"8"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"3020; 3021"	"ENSG00000132475; ENSG00000163041"	"H3-3A; H3-3B"	"hsa:3020; hsa:3021; P06351; P33155; P84243; Q5VV55; Q5VV56; Q66I33; Q9V3W4"	"Gastric cancer network 1; Histone modifications; Tumor suppressor activity of SMARCB1; Ciliary landscape; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DYRK1A involvement regarding cell proliferation in brain development; 4p16.3 copy number variation; 5q35 copy number variation"	"Estrogen-dependent gene expression; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase I Promoter Escape; Inhibition of DNA recombination at telomere; Amyloid fiber formation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; Pre-NOTCH Transcription and Translation; Factors involved in megakaryocyte development and platelet production; Meiotic recombination; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Condensation of Prophase Chromosomes; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"34"	"0"	"7.4"	"13.6"	"7.4"	"18.4"	"4.9"	"6.1"	"14.2"	"18.5"	"19.2"	"45.8"	"52.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHX1"	"Poly(U)-binding-splicing factor PUF60 OS=Homo sapiens OX=9606 GN=PUF60 PE=1 SV=1"	"0.000"	""	"26"	"13"	"23"	"13"	"559"	"59.8"	"5.29"	"4187.51"	"45.54"	"10"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"22827"	"ENSG00000179950; ENSG00000274081"	"PUF60"	"A8K8K8; hsa:22827; Q969E7; Q96D94; Q96H63; Q99628; Q9NZA0; Q9UHX1; Q9UJY7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"963.4"	"764.8"	"944.2"	"1178.1"	"795.8"	"731.3"	"1539.4"	"1609.4"	"2528.5"	"7881.1"	"12538.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYF8"	"Bcl-2-associated transcription factor 1 OS=Homo sapiens OX=9606 GN=BCLAF1 PE=1 SV=2"	"0.000"	""	"17"	"14"	"28"	"13"	"920"	"106.1"	"9.98"	"6315.55"	"45.51"	"13"	"12"	"stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15440"	"9774"	"ENSG00000029363"	"BCLAF1"	"A2RU75; B7ZM58; E1P586; hsa:9774; Q14673; Q86WU6; Q86WY0; Q9NYF8"	"Interactome of polycomb repressive complex 2 (PRC2)"	""	"1"	"0"	"1790.9"	"1780.4"	"1767.1"	"2355.4"	"1553.2"	"1641.6"	"2359.5"	"2444.4"	"2886.0"	"6323.7"	"10296.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ61"	"Telomerase RNA component interacting RNase OS=Homo sapiens OX=9606 GN=TRIR PE=1 SV=1"	"0.000"	""	"25"	"6"	"12"	"6"	"176"	"18.4"	"9.44"	"1129.10"	"45.46"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	""	"79002"	"ENSG00000123144"	"TRIR"	"hsa:79002; Q9BQ61"	""	""	"0"	"0"	"518.3"	"493.3"	"532.8"	"707.0"	"495.0"	"466.1"	"810.2"	"891.6"	"1246.4"	"2468.9"	"2509.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46060"	"Ran GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RANGAP1 PE=1 SV=1"	"0.000"	""	"20"	"11"	"23"	"11"	"587"	"63.5"	"4.68"	"4494.49"	"45.36"	"10"	"11"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07834, Pf13516"	"5905"	"ENSG00000100401"	"RANGAP1"	"hsa:5905; P46060; Q96JJ2"	"22q11.2 copy number variation syndrome; IL-18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Rev-mediated nuclear export of HIV RNA; SUMOylation of DNA replication proteins; Postmitotic nuclear pore complex (NPC) reformation; SUMOylation of nuclear envelope proteins"	"12"	"0"	"724.1"	"677.4"	"841.3"	"1030.6"	"679.8"	"674.0"	"1301.6"	"1323.5"	"1731.5"	"3401.8"	"4800.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60709"	"Actin, cytoplasmic 1 OS=Homo sapiens OX=9606 GN=ACTB PE=1 SV=1"	"0.000"	""	"25"	"8"	"20"	"2"	"375"	"41.7"	"5.48"	"3931.39"	"45.33"	"7"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"60"	"ENSG00000075624"	"ACTB"	"hsa:60; P02570; P60709; P70514; P99021; Q11211; Q64316; Q75MN2; Q96B34; Q96HG5"	"Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; Ebola virus infection in host; Acute viral myocarditis; Thermogenesis; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Regulation of actin cytoskeleton; Network map of SARS-CoV-2 signaling pathway"	"UCH proteinases; Clathrin-mediated endocytosis; DNA Damage Recognition in GG-NER; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHO GTPases Activate WASPs and WAVEs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RHO GTPases activate IQGAPs; RHO GTPases Activate Formins; RHOF GTPase cycle; B-WICH complex positively regulates rRNA expression; Signaling by BRAF and RAF1 fusions; EPHB-mediated forward signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; EPH-ephrin mediated repulsion of cells; HATs acetylate histones; Interaction between L1 and Ankyrins; Prefoldin mediated transfer of substrate  to CCT/TriC; Signaling by RAF1 mutants; Adherens junctions interactions; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Formation of annular gap junctions; Folding of actin by CCT/TriC; Cell-extracellular matrix interactions"	"47"	"0"	"72.2"	"73.5"	"85.3"	"126.2"	"68.8"	"72.3"	"129.8"	"137.5"	"202.3"	"515.9"	"743.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46777"	"60S ribosomal protein L5 OS=Homo sapiens OX=9606 GN=RPL5 PE=1 SV=3"	"0.000"	""	"32"	"12"	"28"	"12"	"297"	"34.3"	"9.72"	"6341.22"	"45.25"	"12"	"10"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf14204, Pf17144"	"6125"	"ENSG00000122406"	"RPL5"	"hsa:6125; P46777; Q32LZ3; Q53HH6; Q9H3F4"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"2304.2"	"2042.5"	"2225.4"	"2737.4"	"2065.7"	"2127.5"	"3045.1"	"3245.6"	"3551.4"	"6327.5"	"9536.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08621"	"U1 small nuclear ribonucleoprotein 70 kDa OS=Homo sapiens OX=9606 GN=SNRNP70 PE=1 SV=2"	"0.000"	""	"30"	"10"	"22"	"10"	"437"	"51.5"	"9.94"	"3620.23"	"45.14"	"8"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf12220"	"6625"	"ENSG00000104852"	"SNRNP70"	"B3KUA3; hsa:6625; P08621; P78493; P78494; Q15364; Q15686; Q15687; Q15689; Q99377; Q9UE45; Q9UE46; Q9UE47; Q9UE48; Q9UFQ6"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1303.2"	"1124.2"	"1326.2"	"1898.2"	"1098.3"	"1072.4"	"1536.3"	"1586.7"	"1703.8"	"2530.8"	"3427.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39748"	"Flap endonuclease 1 OS=Homo sapiens OX=9606 GN=FEN1 PE=1 SV=1"	"0.000"	""	"37"	"11"	"23"	"11"	"380"	"42.6"	"8.62"	"4660.00"	"45.00"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"2237"	"ENSG00000168496"	"FEN1"	"hsa:2237; P39748"	"Base excision repair; DNA repair pathways, full network"	"HDR through MMEJ (alt-NHEJ); Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Removal of the Flap Intermediate; Removal of the Flap Intermediate from the C-strand"	"8"	"0"	"1840.9"	"1487.6"	"1962.1"	"2263.5"	"1607.8"	"1640.3"	"3097.6"	"3189.1"	"4808.9"	"8000.1"	"7191.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35527"	"Keratin, type I cytoskeletal 9 OS=Homo sapiens OX=9606 GN=KRT9 PE=1 SV=3"	"0.000"	""	"17"	"11"	"25"	"10"	"623"	"62.0"	"5.24"	"4827.43"	"44.67"	"9"	"10"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00038"	"3857"	"ENSG00000171403"	"KRT9"	"hsa:3857; O00109; P35527; Q0IJ47; Q14665"	""	"Formation of the cornified envelope"	"2"	"0"	"384.5"	"665.4"	"2943.5"	"1219.8"	"435.9"	"1648.1"	"4890.5"	"3150.3"	"2163.3"	"2836.1"	"1882.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55084"	"Trifunctional enzyme subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=HADHB PE=1 SV=3"	"0.000"	""	"32"	"14"	"23"	"13"	"474"	"51.3"	"9.41"	"5443.50"	"44.67"	"12"	"11"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion;ER/Golgi"	"nucleic acid binding activity;other molecular function"	"Pf00108, Pf02803"	"3032"	"ENSG00000138029"	"HADHB"	"B2RB16; B4E2W0; hsa:3032; O14969; P55084; Q53TA6; Q96C77; Q9H3F5; Q9T2V8"	"Fatty acid beta-oxidation; Valproic acid pathway; Female steroid hormones in cardiomyocyte energy metabolism; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Acyl chain remodeling of CL; mitochondrial fatty acid beta-oxidation of unsaturated fatty acids; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of myristoyl-CoA to lauroyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"12"	"1"	"990.6"	"947.1"	"1166.7"	"1518.7"	"942.3"	"1022.6"	"1632.7"	"1700.1"	"2234.8"	"5161.8"	"9539.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33993"	"DNA replication licensing factor MCM7 OS=Homo sapiens OX=9606 GN=MCM7 PE=1 SV=4"	"0.000"	""	"19"	"12"	"23"	"12"	"719"	"81.3"	"6.46"	"5664.59"	"44.62"	"12"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf14551, Pf17207, Pf17855"	"4176"	"ENSG00000166508"	"MCM7"	"A4D2A1; A4D2A2; E9PGN9; hsa:4176; P33993; Q15076; Q96D34; Q96GL1"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; Ciliary landscape; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"12"	"0"	"712.9"	"624.6"	"802.8"	"1046.6"	"620.6"	"646.4"	"1065.7"	"1095.5"	"1398.7"	"3678.6"	"7763.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00267"	"Transcription elongation factor SPT5 OS=Homo sapiens OX=9606 GN=SUPT5H PE=1 SV=1"	"0.000"	""	"14"	"16"	"26"	"16"	"1087"	"120.9"	"5.06"	"5660.29"	"44.60"	"13"	"12"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf03439, Pf11942"	"6829"	"ENSG00000196235"	"SUPT5H"	"hsa:6829; O00267; O43279; Q59G52; Q99639"	"Initiation of transcription and translation elongation at the HIV-1 LTR; mRNA processing"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"20"	"0"	"1897.6"	"1869.5"	"1988.8"	"2426.4"	"1718.1"	"1796.4"	"2557.5"	"2653.1"	"2900.8"	"4482.3"	"5369.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55265"	"Double-stranded RNA-specific adenosine deaminase OS=Homo sapiens OX=9606 GN=ADAR PE=1 SV=4"	"0.000"	""	"15"	"15"	"26"	"15"	"1226"	"136.0"	"8.65"	"5765.54"	"44.45"	"14"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf02137, Pf02295"	"103"	"ENSG00000160710"	"ADAR"	"B1AQQ9; B1AQR0; D3DV76; hsa:103; O15223; O43859; O43860; P55265; Q9BYM3; Q9BYM4"	"Measles virus infection; Cytosolic DNA-sensing pathway"	"Interferon alpha/beta signaling; C6 deamination of adenosine; Formation of editosomes by ADAR proteins"	"5"	"0"	"1149.9"	"976.7"	"1436.5"	"1833.8"	"1173.6"	"1012.2"	"1794.0"	"1834.9"	"2090.4"	"3922.5"	"6345.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42167"	"Lamina-associated polypeptide 2, isoforms beta/gamma OS=Homo sapiens OX=9606 GN=TMPO PE=1 SV=2"	"0.000"	""	"35"	"12"	"20"	"5"	"454"	"50.6"	"9.38"	"3669.11"	"44.11"	"9"	"11"	""	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf08198"	"7112"	"ENSG00000120802"	"TMPO"	"A2T926; hsa:7112; P42167; Q14861"	"Envelope proteins and their potential roles in EDMD physiopathology; Overlap between signal transduction pathways contributing to LMNA laminopathies"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; RHOG GTPase cycle; RHOD GTPase cycle; RHOF GTPase cycle"	"12"	"7"	"772.2"	"751.9"	"793.9"	"956.5"	"697.3"	"778.3"	"1258.8"	"1310.0"	"1847.0"	"3745.5"	"4744.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26358"	"DNA (cytosine-5)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=DNMT1 PE=1 SV=2"	"0.000"	""	"9"	"13"	"23"	"13"	"1616"	"183.1"	"7.75"	"3543.56"	"44.06"	"10"	"13"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf01426, Pf02008, Pf06464, Pf12047"	"1786"	"ENSG00000130816"	"DNMT1"	"A0AV63; B7ZLW6; hsa:1786; P26358; Q9UHG5; Q9ULA2; Q9UMZ6"	"Trans-sulfuration pathway; One-carbon metabolism; Retinoblastoma gene in cancer; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"SUMOylation of DNA methylation proteins; NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation"	"10"	"0"	"894.7"	"852.2"	"1006.2"	"1220.5"	"865.2"	"842.5"	"1465.9"	"1597.8"	"2009.0"	"3418.4"	"3821.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNX4"	"WD repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=WDR3 PE=1 SV=1"	"0.000"	""	"15"	"11"	"21"	"11"	"943"	"106.0"	"6.64"	"4295.55"	"43.46"	"10"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf04003, Pf12894"	"10885"	"ENSG00000065183"	"WDR3"	"hsa:10885; Q9UNX4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"448.6"	"432.0"	"504.3"	"561.2"	"425.7"	"489.5"	"1138.2"	"1241.8"	"2332.4"	"4246.4"	"3829.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20042"	"Eukaryotic translation initiation factor 2 subunit 2 OS=Homo sapiens OX=9606 GN=EIF2S2 PE=1 SV=2"	"0.000"	""	"40"	"14"	"23"	"14"	"333"	"38.4"	"5.80"	"5157.34"	"43.35"	"11"	"11"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01873"	"8894"	"ENSG00000125977"	"EIF2S2"	"hsa:8894; P20042; Q9BVU0; Q9UJE4"	"Translation factors; Brain-derived neurotrophic factor (BDNF) signaling pathway; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Primary ovarian insufficiency"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; ABC-family proteins mediated transport; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"14"	"0"	"1291.0"	"1023.0"	"1363.2"	"1591.8"	"1210.4"	"1228.8"	"2943.7"	"3240.4"	"5094.3"	"4256.3"	"3206.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05519"	"Serine/arginine-rich splicing factor 11 OS=Homo sapiens OX=9606 GN=SRSF11 PE=1 SV=1"	"0.000"	""	"16"	"9"	"18"	"9"	"484"	"53.5"	"10.52"	"2666.77"	"43.28"	"6"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00076"	"9295"	"ENSG00000116754"	"SRSF11"	"hsa:9295; Q05519; Q5T758; Q8IWE6"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"5"	"0"	"447.6"	"344.9"	"506.3"	"539.6"	"370.0"	"377.7"	"806.6"	"853.6"	"1300.5"	"4746.2"	"7559.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUA2"	"Peptidyl-prolyl cis-trans isomerase-like 4 OS=Homo sapiens OX=9606 GN=PPIL4 PE=1 SV=1"	"0.000"	""	"23"	"10"	"19"	"10"	"492"	"57.2"	"5.92"	"2906.65"	"43.22"	"8"	"10"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00160"	"85313"	"ENSG00000131013"	"PPIL4"	"B2RD34; hsa:85313; Q7Z3Q5; Q8WUA2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"368.7"	"337.9"	"418.3"	"503.0"	"373.8"	"381.3"	"961.2"	"1037.1"	"1875.5"	"5721.8"	"7084.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12268"	"Inosine-5'-monophosphate dehydrogenase 2 OS=Homo sapiens OX=9606 GN=IMPDH2 PE=1 SV=2"	"0.000"	""	"29"	"10"	"19"	"10"	"514"	"55.8"	"6.90"	"5224.18"	"43.05"	"9"	"9"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00478, Pf00571"	"3615"	"ENSG00000178035"	"IMPDH2"	"hsa:3615; P12268; Q6LEF3"	"Rett syndrome causing genes"	"Potential therapeutics for SARS; Neutrophil degranulation; Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"5"	"0"	"489.6"	"393.6"	"455.5"	"684.9"	"380.4"	"385.8"	"775.5"	"840.1"	"1191.7"	"3799.5"	"6631.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVJ6"	"U3 small nucleolar RNA-associated protein 14 homolog A OS=Homo sapiens OX=9606 GN=UTP14A PE=1 SV=1"	"0.000"	""	"19"	"12"	"25"	"10"	"771"	"87.9"	"7.87"	"5052.37"	"43.03"	"11"	"12"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"10813"	"ENSG00000156697"	"UTP14A"	"A8K7A3; A8MVQ1; B4DQ08; E9PEL7; hsa:10813; Q5JYF1; Q9BVJ6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"3"	"1096.8"	"910.8"	"1255.7"	"1364.0"	"1041.3"	"1099.9"	"1419.1"	"1469.4"	"1630.7"	"2439.0"	"2337.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42704"	"Leucine-rich PPR motif-containing protein, mitochondrial OS=Homo sapiens OX=9606 GN=LRPPRC PE=1 SV=3"	"0.000"	""	"10"	"12"	"22"	"12"	"1394"	"157.8"	"6.13"	"4272.03"	"42.96"	"11"	"11"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01535"	"10128"	"ENSG00000138095"	"LRPPRC"	"A0PJE3; A8K1V1; hsa:10128; P42704; Q53PC0; Q53QN7; Q6ZUD8; Q7Z7A6; Q96D84"	"Ciliary landscape"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"4"	"0"	"590.5"	"555.4"	"730.5"	"893.3"	"621.1"	"645.5"	"1115.3"	"1111.1"	"1473.0"	"3832.8"	"5922.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26038"	"Moesin OS=Homo sapiens OX=9606 GN=MSN PE=1 SV=3"	"0.000"	""	"18"	"12"	"27"	"3"	"577"	"67.8"	"6.40"	"4998.81"	"42.91"	"12"	"11"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"4478"	"ENSG00000147065"	"MSN"	"hsa:4478; P26038"	"Glial cell differentiation; AGE/RAGE pathway; Measles virus infection; 16p11.2 proximal deletion syndrome; Regulation of actin cytoskeleton"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Signaling by ALK fusions and activated point mutants"	"10"	"0"	"233.0"	"220.0"	"276.1"	"320.0"	"245.4"	"249.7"	"461.5"	"468.2"	"689.6"	"1025.7"	"1064.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92576"	"PHD finger protein 3 OS=Homo sapiens OX=9606 GN=PHF3 PE=1 SV=3"	"0.000"	""	"8"	"11"	"20"	"11"	"2039"	"229.3"	"6.96"	"3685.28"	"42.85"	"9"	"11"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"23469"	"ENSG00000118482"	"PHF3"	"A3KFI8; hsa:23469; Q14CR5; Q5CZI1; Q5T1T6; Q92576; Q9NQ16; Q9UI45"	""	""	"0"	"0"	"605.0"	"506.7"	"720.6"	"859.8"	"622.1"	"608.3"	"960.0"	"982.6"	"1262.0"	"2462.5"	"3253.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06124"	"Tyrosine-protein phosphatase non-receptor type 11 OS=Homo sapiens OX=9606 GN=PTPN11 PE=1 SV=3"	"0.000"	""	"30"	"12"	"20"	"12"	"593"	"68.0"	"7.30"	"4531.19"	"42.73"	"10"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00102"	"5781"	"ENSG00000179295"	"PTPN11"	"A8K1D9; hsa:5781; Q06124; Q96HD7"	"IL-5 signaling pathway; Heart development; IL-1 signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; IL-4 signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Fragile X syndrome; Cancer immunotherapy by CTLA4 blockade; Cancer immunotherapy by PD-1 blockade; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Insulin signaling; IL-2 signaling pathway; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Orexin receptor pathway; GDNF signaling; Interferon type I signaling pathways; Type II interferon signaling; T-cell receptor signaling pathway"	"PIP3 activates AKT signaling; GPVI-mediated activation cascade; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Platelet sensitization by LDL; CTLA4 inhibitory signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Interleukin-3, Interleukin-5 and GM-CSF signaling; PD-1 signaling; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; Signal regulatory protein family interactions; Constitutive Signaling by Aberrant PI3K in Cancer; RET signaling; PI3K Cascade; Signaling by SCF-KIT; Downstream signal transduction; Tie2 Signaling; Interleukin-6 signaling; Signaling by Leptin; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Signaling by CSF3 (G-CSF); GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; FRS-mediated FGFR1 signaling; PI-3K cascade:FGFR2; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; PI-3K cascade:FGFR3; FRS-mediated FGFR4 signaling; PI-3K cascade:FGFR4; Activated NTRK2 signals through FRS2 and FRS3; Spry regulation of FGF signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; Prolactin receptor signaling; Interleukin-20 family signaling; Netrin mediated repulsion signals; Interleukin-37 signaling; PECAM1 interactions; MET activates PTPN11; STAT5 activation downstream of FLT3 ITD mutants; Regulation of RUNX1 Expression and Activity; STAT5 Activation"	"90"	"0"	"297.0"	"280.9"	"356.7"	"459.5"	"325.7"	"296.2"	"765.1"	"863.4"	"1403.0"	"3136.7"	"3802.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55209"	"Nucleosome assembly protein 1-like 1 OS=Homo sapiens OX=9606 GN=NAP1L1 PE=1 SV=1"	"0.000"	""	"33"	"9"	"17"	"7"	"391"	"45.3"	"4.46"	"2545.70"	"42.71"	"6"	"9"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4673"	"ENSG00000187109"	"NAP1L1"	"B3KNT8; B3KV44; hsa:4673; P55209"	"VEGFA-VEGFR2 signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies"	""	"2"	"2"	"311.6"	"363.3"	"379.0"	"472.6"	"316.9"	"342.1"	"600.5"	"633.0"	"839.5"	"1846.8"	"2608.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52292"	"Importin subunit alpha-1 OS=Homo sapiens OX=9606 GN=KPNA2 PE=1 SV=1"	"0.000"	""	"28"	"12"	"19"	"12"	"529"	"57.8"	"5.40"	"3568.07"	"42.51"	"9"	"10"	"DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3838"	"ENSG00000182481"	"KPNA2"	"B9EJD6; hsa:3838; P52292; Q53YE3; Q6NVW7; Q9BRU5"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Estrogen-dependent gene expression; SARS-CoV-1 activates/modulates innate immune responses; Sensing of DNA Double Strand Breaks; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"8"	"0"	"862.7"	"813.5"	"929.9"	"980.4"	"742.0"	"835.3"	"1301.4"	"1312.4"	"1723.6"	"4298.4"	"6547.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27348"	"14-3-3 protein theta OS=Homo sapiens OX=9606 GN=YWHAQ PE=1 SV=1"	"0.000"	""	"34"	"8"	"26"	"5"	"245"	"27.7"	"4.78"	"5079.21"	"42.26"	"8"	"7"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00244"	"10971"	"ENSG00000134308"	"YWHAQ"	"D6W4Z5; hsa:10971; P27348; Q567U5; Q5TZU8; Q9UP48"	"Cell cycle; Pathogenic Escherichia coli infection; Primary focal segmental glomerulosclerosis (FSGS); IL-3 signaling pathway; Myometrial relaxation and contraction pathways; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Leukocyte-intrinsic Hippo pathway functions; Hepatitis B infection; Opioid receptor pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"TP53 Regulates Metabolic Genes; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Regulation of localization of FOXO transcription factors; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"20"	"0"	"513.3"	"453.9"	"495.1"	"625.4"	"440.0"	"470.3"	"765.6"	"794.8"	"1120.7"	"2366.3"	"3097.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53396"	"ATP-citrate synthase OS=Homo sapiens OX=9606 GN=ACLY PE=1 SV=3"	"0.000"	""	"11"	"11"	"21"	"11"	"1101"	"120.8"	"7.33"	"3469.32"	"42.22"	"8"	"11"	"other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00285, Pf00549, Pf02629, Pf16114"	"47"	"ENSG00000131473"	"ACLY"	"B4DIM0; B4E3P0; hsa:47; P53396; Q13037; Q9BRL0"	"Sterol regulatory element-binding proteins (SREBP) signaling; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Fatty acid biosynthesis; Amino acid metabolism; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer"	"Neutrophil degranulation; ChREBP activates metabolic gene expression; Fatty acyl-CoA biosynthesis"	"10"	"0"	"581.0"	"555.0"	"657.0"	"782.1"	"547.4"	"562.8"	"931.9"	"971.7"	"1341.4"	"3639.3"	"6434.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH65"	"Switch-associated protein 70 OS=Homo sapiens OX=9606 GN=SWAP70 PE=1 SV=1"	"0.000"	""	"26"	"13"	"24"	"13"	"585"	"69.0"	"5.87"	"4865.93"	"42.18"	"13"	"11"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00169"	"23075"	"ENSG00000133789"	"SWAP70"	"D3DQV1; hsa:23075; O75135; Q7LCY6; Q9P061; Q9P0Z8; Q9UH65"	""	"RAC1 GTPase cycle; RAC3 GTPase cycle; RAC2 GTPase cycle"	"3"	"0"	"271.9"	"247.8"	"306.9"	"374.7"	"323.3"	"381.7"	"1661.2"	"1773.1"	"2852.7"	"7685.1"	"9307.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38159"	"RNA-binding motif protein, X chromosome OS=Homo sapiens OX=9606 GN=RBMX PE=1 SV=3"	"0.000"	""	"34"	"10"	"23"	"4"	"391"	"42.3"	"10.05"	"4594.63"	"42.17"	"9"	"9"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08081"	"27316"	"ENSG00000147274"	"RBMX"	"B4E3U4; D3DWH0; E9PG86; hsa:27316; P38159; Q5JQ67; Q8N8Y7; Q969R3"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"8"	"5"	"1908.0"	"2115.3"	"2124.4"	"2702.0"	"1708.8"	"1768.6"	"2467.9"	"2452.0"	"2525.4"	"3921.2"	"6190.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6I3"	"Epsin-1 OS=Homo sapiens OX=9606 GN=EPN1 PE=1 SV=2"	"0.000"	""	"24"	"10"	"16"	"10"	"576"	"60.3"	"4.83"	"2010.75"	"42.15"	"6"	"10"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf01417, Pf02809"	"29924"	"ENSG00000063245"	"EPN1"	"hsa:29924; Q86ST3; Q9HA18; Q9Y6I3"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"5"	"0"	"263.5"	"271.2"	"474.6"	"719.4"	"721.0"	"987.8"	"1632.2"	"1768.7"	"1942.9"	"3084.2"	"3308.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28370"	"Probable global transcription activator SNF2L1 OS=Homo sapiens OX=9606 GN=SMARCA1 PE=1 SV=2"	"0.000"	""	"13"	"14"	"26"	"9"	"1054"	"122.5"	"8.09"	"4604.28"	"42.00"	"13"	"13"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"6594"	"ENSG00000102038"	"SMARCA1"	"hsa:6594; P28370; Q5JV41; Q5JV42"	"Nuclear receptors meta-pathway; Rett syndrome causing genes"	""	"2"	"5"	"1006.6"	"883.4"	"1263.4"	"1510.2"	"978.7"	"1012.3"	"2029.2"	"2046.8"	"3122.9"	"5486.3"	"5179.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40222"	"Alpha-taxilin OS=Homo sapiens OX=9606 GN=TXLNA PE=1 SV=3"	"0.000"	""	"27"	"12"	"20"	"11"	"546"	"61.9"	"6.52"	"3954.27"	"41.96"	"10"	"10"	"transport;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"other molecular function"	"Pf09728"	"200081"	"ENSG00000084652"	"TXLNA"	"D3DPP6; hsa:200081; P40222; Q5TFJ6; Q66K62; Q86T54; Q86T85; Q86T86; Q86Y86; Q86YW3; Q8N2Y3"	""	"Other interleukin signaling"	"1"	"1"	"742.4"	"608.2"	"745.7"	"914.1"	"677.2"	"648.0"	"1256.7"	"1386.9"	"1771.4"	"3435.7"	"3769.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29401"	"Transketolase OS=Homo sapiens OX=9606 GN=TKT PE=1 SV=3"	"0.000"	""	"17"	"8"	"16"	"8"	"623"	"67.8"	"7.66"	"3101.77"	"41.91"	"5"	"7"	"other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00456, Pf02779, Pf02780"	"7086"	"ENSG00000163931"	"TKT"	"A8K089; B4DE31; E7EPA7; hsa:7086; P29401; Q8TBA3; Q96HH3"	"Pentose phosphate metabolism; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate"	"7"	"0"	"235.0"	"187.8"	"295.7"	"428.1"	"226.1"	"257.1"	"509.4"	"573.9"	"900.0"	"4042.9"	"7804.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35659"	"Protein DEK OS=Homo sapiens OX=9606 GN=DEK PE=1 SV=1"	"0.000"	""	"27"	"12"	"27"	"12"	"375"	"42.6"	"8.56"	"5762.31"	"41.90"	"12"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08766"	"7913"	"ENSG00000124795"	"DEK"	"B2R6K6; B4DN37; hsa:7913; P35659; Q5TGV4; Q5TGV5"	"IL-18 signaling pathway; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Transcriptional regulation of granulopoiesis; Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors"	"5"	"0"	"803.6"	"671.5"	"894.3"	"1079.3"	"694.6"	"723.6"	"1785.4"	"1876.3"	"3137.9"	"13372.2"	"10680.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75369"	"Filamin-B OS=Homo sapiens OX=9606 GN=FLNB PE=1 SV=2"	"0.000"	""	"6"	"10"	"17"	"8"	"2602"	"278.0"	"5.73"	"3004.64"	"41.89"	"7"	"10"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2317"	"ENSG00000136068"	"FLNB"	"B2ZZ83; B2ZZ84; B2ZZ85; C9JKE6; C9JMC4; hsa:2317; O75369; Q13706; Q59EC2; Q60FE7; Q6MZJ1; Q8WXS9; Q8WXT0; Q8WXT1; Q8WXT2; Q8WXT3; Q9NRB5; Q9NT26; Q9UEV9"	"Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; NPHP1 deletion syndrome"	"ISG15 antiviral mechanism"	"6"	"1"	"181.7"	"159.4"	"215.4"	"301.5"	"155.3"	"169.5"	"293.3"	"292.2"	"364.5"	"828.8"	"1366.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10567"	"AP-1 complex subunit beta-1 OS=Homo sapiens OX=9606 GN=AP1B1 PE=1 SV=2"	"0.000"	""	"16"	"16"	"28"	"7"	"949"	"104.6"	"5.06"	"5738.45"	"41.87"	"15"	"11"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"327.0"	"313.0"	"361.2"	"451.2"	"319.4"	"413.8"	"1391.3"	"1662.4"	"1913.1"	"3597.6"	"5436.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYA6"	"Beta-catenin-like protein 1 OS=Homo sapiens OX=9606 GN=CTNNBL1 PE=1 SV=1"	"0.000"	""	"15"	"9"	"23"	"9"	"563"	"65.1"	"5.05"	"4393.57"	"41.86"	"9"	"8"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08216"	"56259"	"ENSG00000132792"	"CTNNBL1"	"B4DE16; hsa:56259; Q0VAL9; Q0VAM0; Q53HI8; Q5JWZ2; Q5JWZ3; Q5JWZ7; Q5JWZ8; Q8N454; Q8NCL2; Q8TBD6; Q8WYA6; Q96KD2; Q9H7A5; Q9NQF9; Q9NTX0; Q9Y3M7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"571.4"	"469.1"	"662.7"	"789.4"	"498.5"	"516.4"	"1161.4"	"1172.0"	"1932.0"	"8108.2"	"10062.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09028"	"Histone-binding protein RBBP4 OS=Homo sapiens OX=9606 GN=RBBP4 PE=1 SV=3"	"0.000"	""	"30"	"13"	"22"	"6"	"425"	"47.6"	"4.89"	"4444.61"	"41.86"	"12"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5928"	"ENSG00000162521"	"RBBP4"	"B2R6G9; B4DRH0; D3DPQ3; hsa:5928; P31149; Q09028; Q53H02; Q96BV9"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Pleural mesothelioma; DYRK1A involvement regarding cell proliferation in brain development"	"HCMV Early Events; Transcriptional Regulation by E2F6; G1/S-Specific Transcription; Potential therapeutics for SARS; Deposition of new CENPA-containing nucleosomes at the centromere; Oxidative Stress Induced Senescence; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; PKMTs methylate histone lysines; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation; Polo-like kinase mediated events; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"28"	"6"	"1058.2"	"1114.6"	"1090.7"	"1443.2"	"939.5"	"1033.4"	"1488.1"	"1598.8"	"1951.6"	"4681.2"	"6004.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23381"	"Tryptophan--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=WARS1 PE=1 SV=2"	"0.000"	""	"29"	"10"	"16"	"10"	"471"	"53.1"	"6.23"	"1977.13"	"41.82"	"6"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00458, Pf00579"	"7453"	"ENSG00000140105"	"WARS1"	"A6NGN1; A6NID3; hsa:7453; P23381; P78535; Q502Y0; Q53XB6; Q9UDI5; Q9UDL3"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"3"	"0"	"103.9"	"101.1"	"124.3"	"188.7"	"110.4"	"119.5"	"428.9"	"488.6"	"923.1"	"4022.2"	"6529.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNF0"	"Protein kinase C and casein kinase substrate in neurons protein 2 OS=Homo sapiens OX=9606 GN=PACSIN2 PE=1 SV=2"	"0.000"	""	"22"	"10"	"19"	"10"	"486"	"55.7"	"5.20"	"3106.86"	"41.82"	"7"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf00611"	"11252"	"ENSG00000100266"	"PACSIN2"	"hsa:11252; O95921; Q96HV9; Q9H0D3; Q9NPN1; Q9UNF0; Q9Y4V2"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"360.8"	"303.3"	"423.1"	"483.3"	"353.4"	"343.2"	"789.9"	"821.2"	"1316.5"	"5657.3"	"8384.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DI7"	"U5 small nuclear ribonucleoprotein 40 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP40 PE=1 SV=1"	"0.000"	""	"34"	"9"	"21"	"9"	"357"	"39.3"	"8.10"	"3542.21"	"41.61"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"9410"	"ENSG00000060688"	"SNRNP40"	"B4DQJ1; hsa:9410; O75938; O95320; Q96DI7"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"663.4"	"638.7"	"638.8"	"764.7"	"543.9"	"596.6"	"1076.8"	"1160.9"	"1470.2"	"4556.8"	"6046.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14141"	"Septin-6 OS=Homo sapiens OX=9606 GN=SEPTIN6 PE=1 SV=4"	"0.000"	""	"20"	"9"	"20"	"1"	"434"	"49.7"	"6.67"	"3584.55"	"41.33"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00735"	"23157"	"ENSG00000125354"	"SEPTIN6"	"hsa:23157; Q14141; Q5JTK0; Q969W5; Q96A13; Q96GR1; Q96P86; Q96P87"	"2q37 copy number variation syndrome"	""	"1"	"0"	"46.4"	"41.3"	"49.0"	"62.9"	"36.3"	"43.4"	"91.3"	"83.7"	"133.6"	"357.8"	"461.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49589"	"Cysteine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=CARS1 PE=1 SV=3"	"0.000"	""	"17"	"10"	"16"	"10"	"748"	"85.4"	"6.76"	"2486.15"	"41.28"	"6"	"10"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01406"	"833"	"ENSG00000110619; ENSG00000278191"	"CARS1"	"hsa:833; P49589; Q53XI8; Q5HYE4; Q9HD24; Q9HD25"	""	"Cytosolic tRNA aminoacylation; Signaling by ALK fusions and activated point mutants"	"2"	"0"	"150.7"	"128.7"	"183.2"	"214.5"	"147.5"	"147.1"	"360.2"	"404.2"	"764.3"	"2833.9"	"6143.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32119"	"Peroxiredoxin-2 OS=Homo sapiens OX=9606 GN=PRDX2 PE=1 SV=5"	"0.000"	""	"31"	"8"	"23"	"7"	"198"	"21.9"	"5.97"	"4924.31"	"41.26"	"6"	"8"	"cell cycle OR cell proliferation;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"7001"	"ENSG00000167815"	"PRDX2"	"A8K0C0; hsa:7001; P31945; P32118; P32119; P35701; Q6FHG4; Q92763; Q9UC23"	"Selenium micronutrient network; VEGFA-VEGFR2 signaling"	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Detoxification of Reactive Oxygen Species; TP53 Regulates Metabolic Genes"	"5"	"0"	"488.5"	"442.0"	"630.7"	"811.6"	"404.9"	"457.5"	"935.9"	"1026.2"	"1522.3"	"5008.2"	"7240.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ST2"	"Protein IWS1 homolog OS=Homo sapiens OX=9606 GN=IWS1 PE=1 SV=2"	"0.000"	""	"10"	"7"	"19"	"7"	"819"	"91.9"	"4.69"	"3949.22"	"41.26"	"6"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	""	"Pf08711"	"55677"	"ENSG00000163166"	"IWS1"	"hsa:55677; Q2TB65; Q6P157; Q8N3E8; Q96MI7; Q96ST2; Q9NV97; Q9NWH8"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"3"	"0"	"1181.5"	"1126.1"	"1423.8"	"1640.5"	"1126.8"	"1163.5"	"1489.2"	"1522.6"	"1645.5"	"2373.0"	"3323.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36873"	"Serine/threonine-protein phosphatase PP1-gamma catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CC PE=1 SV=1"	"0.000"	""	"32"	"9"	"19"	"2"	"323"	"37.0"	"6.54"	"3740.60"	"41.14"	"8"	"9"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5501"	"ENSG00000186298"	"PPP1CC"	"hsa:5501; P36873"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; Neuroinflammation and glutamatergic signaling"	"Separation of Sister Chromatids; Triglyceride catabolism; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; Downregulation of TGF-beta receptor signaling"	"16"	"0"	"374.7"	"333.4"	"401.4"	"420.7"	"302.0"	"332.4"	"480.2"	"495.1"	"628.0"	"1246.1"	"1674.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99615"	"DnaJ homolog subfamily C member 7 OS=Homo sapiens OX=9606 GN=DNAJC7 PE=1 SV=2"	"0.000"	""	"29"	"12"	"25"	"12"	"494"	"56.4"	"6.96"	"4608.18"	"41.06"	"9"	"11"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf13181, Pf13414, Pf13432"	"7266"	"ENSG00000168259"	"DNAJC7"	"hsa:7266; Q7Z784; Q99615"	"Constitutive androstane receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway"	"Regulation of HSF1-mediated heat shock response"	"4"	"0"	"764.6"	"682.7"	"911.9"	"987.7"	"787.9"	"738.3"	"1536.3"	"1611.4"	"2329.2"	"6054.6"	"8799.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11586"	"C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=3"	"0.000"	""	"17"	"12"	"20"	"12"	"935"	"101.5"	"7.30"	"4006.33"	"41.05"	"10"	"10"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"696.1"	"602.4"	"718.7"	"844.6"	"585.1"	"553.1"	"919.1"	"968.1"	"1186.4"	"2740.5"	"4308.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13428"	"Treacle protein OS=Homo sapiens OX=9606 GN=TCOF1 PE=1 SV=3"	"0.000"	""	"10"	"15"	"27"	"15"	"1488"	"152.0"	"9.04"	"6287.23"	"40.86"	"15"	"11"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03546"	"6949"	"ENSG00000070814"	"TCOF1"	"A0JLU0; B4E111; hsa:6949; Q13428; Q6SC72; Q7Z5W9; Q96A52; Q99408; Q99860"	""	""	"0"	"0"	"2247.1"	"1880.7"	"2262.7"	"2447.5"	"1911.4"	"2083.9"	"2561.7"	"2570.8"	"2993.4"	"4463.6"	"5143.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULC4"	"Malignant T-cell-amplified sequence 1 OS=Homo sapiens OX=9606 GN=MCTS1 PE=1 SV=1"	"0.000"	""	"52"	"7"	"18"	"7"	"181"	"20.5"	"8.82"	"4188.77"	"40.77"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf01472, Pf17832"	"28985"	"ENSG00000232119; ENSG00000288295"	"MCTS1"	"B4DGY2; hsa:28985; Q502X6; Q9ULC4"	""	""	"0"	"0"	"113.3"	"100.2"	"134.0"	"195.2"	"127.3"	"116.5"	"616.6"	"705.3"	"1628.5"	"4444.7"	"4655.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSL3"	"Dedicator of cytokinesis protein 11 OS=Homo sapiens OX=9606 GN=DOCK11 PE=1 SV=2"	"0.000"	""	"7"	"10"	"24"	"10"	"2073"	"237.5"	"7.74"	"5501.01"	"40.59"	"10"	"8"	"signal transduction;other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"139818"	"ENSG00000147251"	"DOCK11"	"A6NMF0; hsa:139818; Q5JSL3; Q66M66; Q6ZUJ5; Q86VU8; Q96MN3"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	"3"	"0"	"365.0"	"347.7"	"515.9"	"542.4"	"655.8"	"1530.1"	"2986.7"	"2984.7"	"1745.9"	"1011.0"	"1508.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46940"	"Ras GTPase-activating-like protein IQGAP1 OS=Homo sapiens OX=9606 GN=IQGAP1 PE=1 SV=1"	"0.000"	""	"9"	"11"	"21"	"10"	"1657"	"189.1"	"6.48"	"4714.72"	"40.56"	"11"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"8826"	"ENSG00000140575"	"IQGAP1"	"A7MBM3; hsa:8826; P46940"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Ciliary landscape; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases activate IQGAPs; RAC2 GTPase cycle; RHOV GTPase cycle; Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; RHOU GTPase cycle; Nephrin family interactions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"0"	"339.4"	"299.8"	"383.0"	"461.8"	"332.9"	"354.8"	"842.6"	"882.4"	"1587.9"	"3503.8"	"3247.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07197"	"Neurofilament medium polypeptide OS=Homo sapiens OX=9606 GN=NEFM PE=1 SV=3"	"0.000"	""	"14"	"12"	"25"	"11"	"916"	"102.4"	"4.91"	"5086.98"	"40.51"	"12"	"10"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"4741"	"ENSG00000104722"	"NEFM"	"B4DGN2; E9PBF7; hsa:4741; P07197; Q4QRK6"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; Ciliary landscape"	""	"3"	"0"	"1691.2"	"1423.3"	"1588.3"	"1856.4"	"1366.6"	"1579.3"	"1960.7"	"2091.3"	"2325.8"	"3881.5"	"4719.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43172"	"U4/U6 small nuclear ribonucleoprotein Prp4 OS=Homo sapiens OX=9606 GN=PRPF4 PE=1 SV=2"	"0.000"	""	"26"	"10"	"20"	"10"	"522"	"58.4"	"7.42"	"4288.25"	"40.39"	"9"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08799"	"9128"	"ENSG00000136875"	"PRPF4"	"hsa:9128; O43172; O43445; O43864; Q5T1M8; Q96DG2; Q96IK4"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"737.7"	"554.0"	"729.1"	"839.4"	"644.0"	"627.2"	"907.6"	"959.7"	"1198.0"	"2427.2"	"3235.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29692"	"Elongation factor 1-delta OS=Homo sapiens OX=9606 GN=EEF1D PE=1 SV=5"	"0.000"	""	"47"	"12"	"24"	"10"	"281"	"31.1"	"5.01"	"5765.69"	"40.38"	"11"	"7"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00736, Pf10587"	"1936"	"ENSG00000104529; ENSG00000273594"	"EEF1D"	"B4DDU4; D3DWK3; E9PBQ9; hsa:1936; P29692; Q4VBZ6; Q969J1; Q96I38"	"Translation factors"	"Eukaryotic Translation Elongation"	"2"	"0"	"810.2"	"710.7"	"826.6"	"1024.6"	"683.2"	"755.0"	"1103.1"	"1136.7"	"1351.1"	"3322.3"	"4305.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39687"	"Acidic leucine-rich nuclear phosphoprotein 32 family member A OS=Homo sapiens OX=9606 GN=ANP32A PE=1 SV=1"	"0.000"	""	"37"	"10"	"19"	"7"	"249"	"28.6"	"4.09"	"3051.26"	"40.36"	"7"	"9"	"transport;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf14580"	"8125"	"ENSG00000140350"	"ANP32A"	"B2R6T4; hsa:8125; P39687; Q53FK4; Q5J8L8; Q7M4N6"	"IL-18 signaling pathway"	"HuR (ELAVL1) binds and stabilizes mRNA"	"2"	"3"	"906.9"	"955.4"	"1006.0"	"1243.6"	"866.9"	"845.2"	"1276.5"	"1298.4"	"1451.6"	"2529.2"	"3095.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11277"	"Spectrin beta chain, erythrocytic OS=Homo sapiens OX=9606 GN=SPTB PE=1 SV=5"	"0.000"	""	"3"	"7"	"25"	"1"	"2137"	"246.3"	"5.27"	"4044.28"	"40.31"	"7"	"7"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00307, Pf00435"	"6710"	"ENSG00000070182"	"SPTB"	"hsa:6710; P11277; Q15510; Q15519"	""	"COPI-mediated anterograde transport; RAF/MAP kinase cascade; NCAM signaling for neurite out-growth; Interaction between L1 and Ankyrins"	"4"	"0"	"11.7"	"11.9"	"17.8"	"23.3"	"13.6"	"15.7"	"30.7"	"31.8"	"44.4"	"123.0"	"178.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWY3"	"U4/U6 small nuclear ribonucleoprotein Prp31 OS=Homo sapiens OX=9606 GN=PRPF31 PE=1 SV=2"	"0.000"	""	"23"	"9"	"19"	"9"	"499"	"55.4"	"5.78"	"3859.90"	"40.29"	"8"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf09785"	"26121"	"ENSG00000105618; ENSG00000274144; ENSG00000274651; ENSG00000274894; ENSG00000275117; ENSG00000275885; ENSG00000276421; ENSG00000277154; ENSG00000277707; ENSG00000277953"	"PRPF31"	"E7ESA8; F1T0A4; F1T0A5; hsa:26121; Q17RB4; Q8N7F9; Q8WWY3; Q9H271; Q9Y439"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1234.1"	"1053.0"	"1068.0"	"1311.5"	"999.0"	"1042.7"	"1412.6"	"1482.7"	"1689.5"	"3295.4"	"4122.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05023"	"Sodium/potassium-transporting ATPase subunit alpha-1 OS=Homo sapiens OX=9606 GN=ATP1A1 PE=1 SV=1"	"0.000"	""	"13"	"10"	"21"	"10"	"1023"	"112.8"	"5.49"	"3757.25"	"40.27"	"9"	"10"	"transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf13246"	"476"	"ENSG00000163399"	"ATP1A1"	"B2RBR6; B7Z2T5; B7Z3U6; F5H3A1; hsa:476; P05023; Q16689; Q6LDM4; Q9UCN1; Q9UJ20; Q9UJ21"	"Pre-implantation embryo; Proximal tubule transport; Arsenic metabolism and reactive oxygen species generation"	"Potential therapeutics for SARS; Ion homeostasis; Ion transport by P-type ATPases"	"6"	"0"	"359.5"	"299.9"	"410.5"	"458.9"	"336.2"	"330.6"	"656.3"	"671.3"	"1078.7"	"3147.6"	"4539.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15717"	"ELAV-like protein 1 OS=Homo sapiens OX=9606 GN=ELAVL1 PE=1 SV=2"	"0.000"	""	"35"	"10"	"23"	"10"	"326"	"36.1"	"9.17"	"4443.57"	"40.25"	"10"	"9"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1994"	"ENSG00000066044"	"ELAVL1"	"B4DVB8; hsa:1994; Q15717; Q53XN6; Q9BTT1"	"AMP-activated protein kinase signaling; Endoderm differentiation; Pre-implantation embryo; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Gastrin signaling pathway; IL-18 signaling pathway; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; 1p36 copy number variation syndrome"	"HuR (ELAVL1) binds and stabilizes mRNA"	"10"	"0"	"830.7"	"761.8"	"1074.1"	"1604.1"	"701.9"	"641.8"	"1285.1"	"1388.2"	"1622.4"	"3564.1"	"5135.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18754"	"Regulator of chromosome condensation OS=Homo sapiens OX=9606 GN=RCC1 PE=1 SV=1"	"0.000"	""	"22"	"9"	"18"	"8"	"421"	"44.9"	"7.52"	"3381.72"	"40.23"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00415"	"1104"	"ENSG00000180198"	"RCC1"	"hsa:1104; P18754; Q16269; Q6NT97"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation"	"4"	"1"	"1270.0"	"989.4"	"1462.7"	"1626.9"	"1077.8"	"1178.9"	"1712.4"	"1834.5"	"2199.2"	"4109.5"	"4349.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX12"	"Cell division cycle and apoptosis regulator protein 1 OS=Homo sapiens OX=9606 GN=CCAR1 PE=1 SV=2"	"0.000"	""	"14"	"14"	"24"	"14"	"1150"	"132.7"	"5.76"	"4773.51"	"40.18"	"13"	"11"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf14443, Pf14444, Pf19256, Pf19257"	"55749"	"ENSG00000060339"	"CCAR1"	"A0JLT7; A1L4P7; A8K9D4; B4DNP8; B4DRK8; hsa:55749; Q32NE3; Q5EBM3; Q5VUP6; Q6PIZ0; Q6X935; Q8IX12; Q9H8N4; Q9NVA7; Q9NVQ0; Q9NWM6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"875.2"	"708.6"	"960.6"	"1292.7"	"759.6"	"793.4"	"1252.3"	"1291.5"	"1496.7"	"3180.3"	"4866.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11387"	"DNA topoisomerase 1 OS=Homo sapiens OX=9606 GN=TOP1 PE=1 SV=2"	"0.000"	""	"14"	"11"	"26"	"11"	"765"	"90.7"	"9.31"	"4596.90"	"40.10"	"10"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf01028, Pf02919, Pf14370"	"7150"	"ENSG00000198900"	"TOP1"	"A8KA78; E1P5W3; hsa:7150; O43256; P11387; Q12855; Q12856; Q15610; Q5TFY3; Q9UJN0"	"Ebola virus infection in host; 15q25 copy number variation"	"SUMOylation of DNA replication proteins"	"3"	"0"	"845.2"	"686.0"	"919.3"	"1087.0"	"823.8"	"847.0"	"1629.6"	"1717.8"	"2883.0"	"5224.6"	"5199.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95782"	"AP-2 complex subunit alpha-1 OS=Homo sapiens OX=9606 GN=AP2A1 PE=1 SV=3"	"0.000"	""	"16"	"12"	"24"	"9"	"977"	"107.5"	"7.03"	"3438.72"	"40.10"	"9"	"12"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01602, Pf02296, Pf02883"	"160"	"ENSG00000196961"	"AP2A1"	"hsa:160; O95782; Q96CI7; Q96PP6; Q96PP7; Q9H070"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; mBDNF and proBDNF regulation of GABA neurotransmission"	"Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Trafficking of GluR2-containing AMPA receptors; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"20"	"3"	"470.9"	"472.6"	"587.4"	"709.8"	"530.4"	"737.8"	"2843.0"	"3561.0"	"4060.5"	"4263.1"	"4059.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15075"	"Early endosome antigen 1 OS=Homo sapiens OX=9606 GN=EEA1 PE=1 SV=2"	"0.000"	""	"10"	"11"	"21"	"11"	"1411"	"162.4"	"5.68"	"4295.02"	"39.98"	"11"	"10"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363"	"8411"	"ENSG00000102189"	"EEA1"	"hsa:8411; Q14221; Q15075"	"VEGFA-VEGFR2 signaling"	"Toll Like Receptor 9 (TLR9) Cascade"	"2"	"0"	"185.6"	"154.3"	"224.9"	"287.7"	"177.3"	"191.5"	"515.2"	"559.7"	"988.9"	"2479.0"	"3711.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96E39"	"RNA binding motif protein, X-linked-like-1 OS=Homo sapiens OX=9606 GN=RBMXL1 PE=1 SV=1"	"0.000"	""	"29"	"8"	"22"	"2"	"390"	"42.1"	"9.89"	"4022.05"	"39.97"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf08081"	"494115"	"ENSG00000213516"	"RBMXL1"	"hsa:494115; Q96E39"	""	""	"0"	"0"	"522.0"	"529.9"	"609.2"	"728.8"	"470.6"	"483.1"	"700.9"	"680.4"	"758.5"	"1524.5"	"2424.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI27"	"THO complex subunit 2 OS=Homo sapiens OX=9606 GN=THOC2 PE=1 SV=2"	"0.000"	""	"7"	"9"	"25"	"9"	"1593"	"182.7"	"8.44"	"4561.18"	"39.95"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf11262, Pf11732, Pf16134"	"57187"	"ENSG00000125676"	"THOC2"	"A6NM50; hsa:57187; Q5JZ12; Q6IN92; Q8NI27; Q9H8I6"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"1343.5"	"1119.1"	"1260.7"	"1465.9"	"1136.3"	"1239.1"	"1727.5"	"1718.9"	"2245.4"	"3773.9"	"4799.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11940"	"Polyadenylate-binding protein 1 OS=Homo sapiens OX=9606 GN=PABPC1 PE=1 SV=2"	"0.000"	""	"22"	"12"	"26"	"9"	"636"	"70.6"	"9.50"	"5048.95"	"39.89"	"12"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"26986"	"ENSG00000070756"	"PABPC1"	"hsa:26986; P11940; Q15097; Q93004"	"Translation factors; Endoderm differentiation; VEGFA-VEGFR2 signaling; Acute viral myocarditis"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"11"	"2"	"1363.9"	"1332.9"	"1389.4"	"1762.3"	"1276.6"	"1299.7"	"1819.2"	"1830.9"	"1957.4"	"3507.9"	"5132.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16531"	"DNA damage-binding protein 1 OS=Homo sapiens OX=9606 GN=DDB1 PE=1 SV=1"	"0.000"	""	"11"	"12"	"22"	"12"	"1140"	"126.9"	"5.26"	"3643.12"	"39.81"	"10"	"12"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03178, Pf10433"	"1642"	"ENSG00000167986"	"DDB1"	"A6NG77; B2R648; B4DG00; hsa:1642; O15176; Q13289; Q16531; Q58F96"	"Hippo-Merlin signaling dysregulation; Hepatitis B infection; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"14"	"0"	"653.2"	"548.4"	"719.3"	"910.9"	"611.6"	"649.2"	"1108.8"	"1157.9"	"1585.4"	"5104.8"	"7616.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96AG4"	"Leucine-rich repeat-containing protein 59 OS=Homo sapiens OX=9606 GN=LRRC59 PE=1 SV=1"	"0.000"	""	"29"	"8"	"18"	"8"	"307"	"34.9"	"9.57"	"2979.80"	"39.78"	"6"	"7"	""	"other membranes;mitochondrion;ER/Golgi;nucleus;other cell component"	""	"Pf13855"	"55379"	"ENSG00000108829"	"LRRC59"	"B2RE83; D3DTX8; hsa:55379; Q96AG4; Q9P189"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"975.5"	"1004.6"	"1060.6"	"1364.2"	"859.6"	"901.8"	"1582.8"	"1679.6"	"2275.2"	"4754.3"	"5670.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13616"	"Cullin-1 OS=Homo sapiens OX=9606 GN=CUL1 PE=1 SV=2"	"0.000"	""	"16"	"11"	"18"	"11"	"776"	"89.6"	"8.00"	"2563.82"	"39.50"	"8"	"9"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8454"	"ENSG00000055130"	"CUL1"	"D3DWG3; hsa:8454; O60719; Q08AL6; Q13616; Q8IYW1"	"Cell cycle; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Pleural mesothelioma; Notch signaling pathway"	"Circadian Clock; Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"40"	"0"	"368.4"	"369.2"	"465.2"	"544.1"	"361.0"	"384.5"	"1039.5"	"1101.2"	"1964.7"	"5255.2"	"6373.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78406"	"mRNA export factor OS=Homo sapiens OX=9606 GN=RAE1 PE=1 SV=1"	"0.000"	""	"32"	"10"	"19"	"10"	"368"	"40.9"	"7.83"	"4212.92"	"39.26"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00400"	"8480"	"ENSG00000101146"	"RAE1"	"A8K882; hsa:8480; O15306; P78406; Q3SYL7; Q5TCH8; Q6V708; Q9H100; Q9NQM6"	"IL-18 signaling pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Transcriptional regulation by small RNAs; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"30"	"0"	"1125.4"	"863.3"	"1200.5"	"1402.4"	"1113.1"	"1080.7"	"1825.8"	"1878.5"	"2414.4"	"4708.8"	"7050.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VUJ6"	"Leucine-rich repeat and calponin homology domain-containing protein 2 OS=Homo sapiens OX=9606 GN=LRCH2 PE=1 SV=2"	"0.000"	""	"18"	"8"	"14"	"8"	"765"	"84.5"	"6.55"	"3067.45"	"39.11"	"5"	"7"	""	""	""	"Pf00307, Pf13855"	"57631"	"ENSG00000130224"	"LRCH2"	"F5H2T1; hsa:57631; Q08AD5; Q5VUJ6; Q9HA88; Q9P233"	""	""	"0"	"0"	"282.9"	"277.0"	"326.7"	"383.8"	"288.1"	"358.7"	"603.2"	"673.3"	"895.6"	"1653.1"	"1999.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41091"	"Eukaryotic translation initiation factor 2 subunit 3 OS=Homo sapiens OX=9606 GN=EIF2S3 PE=1 SV=3"	"0.000"	""	"24"	"9"	"20"	"9"	"472"	"51.1"	"8.40"	"4212.20"	"38.84"	"7"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf09173"	"1968"	"ENSG00000130741"	"EIF2S3"	"A0A024RBY4; A8K2Y2; B2R5N2; B5BTZ4; hsa:1968; P41091; Q53HK3"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"12"	"0"	"818.2"	"738.9"	"931.3"	"1014.0"	"877.9"	"861.4"	"2451.0"	"2705.2"	"4808.4"	"5238.8"	"3793.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62857"	"40S ribosomal protein S28 OS=Homo sapiens OX=9606 GN=RPS28 PE=1 SV=1"	"0.000"	""	"72"	"8"	"20"	"8"	"69"	"7.8"	"10.70"	"4263.90"	"38.83"	"8"	"8"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01200"	"6234"	"ENSG00000233927"	"RPS28"	"hsa:6234; P25112; P62857"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery"	"19"	"0"	"1273.2"	"834.5"	"1100.2"	"1131.6"	"831.1"	"866.5"	"1215.0"	"1178.3"	"1279.8"	"2449.0"	"3734.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13838"	"Spliceosome RNA helicase DDX39B OS=Homo sapiens OX=9606 GN=DDX39B PE=1 SV=1"	"0.000"	""	"27"	"11"	"21"	"4"	"428"	"49.0"	"5.67"	"3685.71"	"38.71"	"9"	"10"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"7919"	"ENSG00000198563; ENSG00000215425; ENSG00000225073; ENSG00000225859; ENSG00000229496; ENSG00000230624; ENSG00000235439"	"DDX39B"	"B0S8C0; hsa:7919; O43496; Q0EFA1; Q13838; Q2L6F9; Q53GL9; Q5RJ64; Q5RJ66; Q5ST94; Q5STB4; Q5STB5; Q5STB7; Q5STB8; Q5STU4; Q5STU5; Q5STU6; Q5STU8; Q71V76"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; RHOBTB2 GTPase cycle; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"6"	"465.9"	"456.5"	"585.6"	"864.6"	"434.0"	"454.2"	"888.8"	"965.0"	"1273.0"	"3396.0"	"6518.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35241"	"Radixin OS=Homo sapiens OX=9606 GN=RDX PE=1 SV=1"	"0.000"	""	"20"	"14"	"27"	"3"	"583"	"68.5"	"6.37"	"5508.34"	"38.68"	"14"	"11"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf00769, Pf09379, Pf09380, Pf20492"	"5962"	"ENSG00000137710"	"RDX"	"A7YIJ8; A7YIK0; A7YIK3; B7Z9U6; F5H1A7; hsa:5962; P35241; Q86Y61"	"Regulation of actin cytoskeleton"	"Recycling pathway of L1; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"2"	"475.5"	"486.8"	"497.8"	"510.9"	"476.6"	"471.3"	"707.0"	"750.9"	"929.5"	"1357.4"	"1285.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62140"	"Serine/threonine-protein phosphatase PP1-beta catalytic subunit OS=Homo sapiens OX=9606 GN=PPP1CB PE=1 SV=3"	"0.000"	""	"29"	"8"	"17"	"1"	"327"	"37.2"	"6.19"	"3378.40"	"38.53"	"7"	"8"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00149, Pf16891"	"5500"	"ENSG00000213639"	"PPP1CB"	"B2R5V4; D6W565; hsa:5500; P37140; P62140; Q5U087; Q6FG45"	"Common pathways underlying drug addiction; Focal adhesion; Hippo-Merlin signaling dysregulation; 22q11.2 copy number variation syndrome; Airway smooth muscle cell contraction; Neuroinflammation and glutamatergic signaling; G13 signaling pathway"	"RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Triglyceride catabolism; Regulation of PLK1 Activity at G2/M Transition; Circadian Clock; RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling; RHO GTPases activate PAKs; Downregulation of TGF-beta receptor signaling"	"18"	"0"	"67.8"	"61.9"	"73.2"	"93.1"	"71.6"	"70.7"	"112.0"	"119.6"	"175.1"	"467.2"	"601.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2TAY7"	"WD40 repeat-containing protein SMU1 OS=Homo sapiens OX=9606 GN=SMU1 PE=1 SV=2"	"0.000"	""	"21"	"10"	"23"	"10"	"513"	"57.5"	"7.18"	"4550.88"	"38.52"	"10"	"9"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf17814"	"55234"	"ENSG00000122692"	"SMU1"	"B4E3L0; hsa:55234; Q2TAY7; Q9BU59; Q9HA96; Q9NVD1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"506.5"	"507.1"	"578.2"	"807.7"	"505.2"	"504.0"	"939.9"	"1002.5"	"1390.6"	"3365.9"	"4371.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98175"	"RNA-binding protein 10 OS=Homo sapiens OX=9606 GN=RBM10 PE=1 SV=3"	"0.000"	""	"14"	"10"	"17"	"10"	"930"	"103.5"	"5.97"	"2825.23"	"38.49"	"7"	"9"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"8241"	"ENSG00000182872"	"RBM10"	"A0A0A0MR66; C4AM81; hsa:8241; P98175; Q14136; Q5JRR2; Q9BTE4; Q9BTX0; Q9NTB1"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"1003.3"	"838.3"	"1036.0"	"1226.0"	"887.1"	"875.0"	"1254.4"	"1274.2"	"1591.4"	"3465.9"	"4529.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2NL82"	"Pre-rRNA-processing protein TSR1 homolog OS=Homo sapiens OX=9606 GN=TSR1 PE=1 SV=1"	"0.000"	""	"17"	"9"	"18"	"9"	"804"	"91.8"	"7.42"	"2972.71"	"38.45"	"7"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04950, Pf08142"	"55720"	"ENSG00000167721"	"TSR1"	"hsa:55720; Q2NL82; Q8WUY5; Q9NVT0; Q9P2E6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"228.6"	"219.4"	"279.7"	"350.1"	"249.8"	"277.3"	"704.9"	"792.3"	"1191.3"	"2672.3"	"2764.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86V81"	"THO complex subunit 4 OS=Homo sapiens OX=9606 GN=ALYREF PE=1 SV=3"	"0.000"	""	"42"	"6"	"9"	"6"	"257"	"26.9"	"11.15"	"826.32"	"38.37"	"2"	"6"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf13865"	"10189"	""	"ALYREF"	"hsa:10189; O43672; Q86V81"	""	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"7"	"0"	"173.5"	"235.4"	"181.8"	"265.8"	"169.4"	"146.4"	"279.8"	"305.2"	"402.2"	"1255.4"	"2059.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Y6"	"DNA-directed RNA polymerase I subunit RPA2 OS=Homo sapiens OX=9606 GN=POLR1B PE=1 SV=2"	"0.000"	""	"11"	"9"	"20"	"9"	"1135"	"128.1"	"7.83"	"3857.57"	"38.34"	"9"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf06883"	"84172"	"ENSG00000125630"	"POLR1B"	"B7Z6Y7; B7Z823; F5GZX4; F8W898; hsa:84172; Q2TAM4; Q585T5; Q6ZRR2; Q9H9D3; Q9H9Y6"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"186.1"	"162.6"	"218.3"	"269.9"	"207.0"	"197.2"	"642.1"	"719.7"	"1303.8"	"3385.1"	"4649.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95831"	"Apoptosis-inducing factor 1, mitochondrial OS=Homo sapiens OX=9606 GN=AIFM1 PE=1 SV=1"	"0.000"	""	"19"	"9"	"19"	"9"	"613"	"66.9"	"8.95"	"3971.18"	"38.28"	"9"	"8"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00070, Pf14721"	"9131"	"ENSG00000156709"	"AIFM1"	"A4QPB4; B1ALN1; B2RB08; D3DTE9; E9PRR0; hsa:9131; O95831; Q1L6K4; Q1L6K6; Q2QKE4; Q5JUZ7; Q6I9X6; Q9Y3I3; Q9Y3I4"	"Apoptosis modulation and signaling; Nanomaterial induced apoptosis; Apoptosis modulation by HSP70"	""	"3"	"0"	"426.0"	"423.5"	"466.5"	"608.6"	"408.4"	"407.1"	"719.0"	"783.4"	"980.5"	"3423.3"	"5601.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54819"	"Adenylate kinase 2, mitochondrial OS=Homo sapiens OX=9606 GN=AK2 PE=1 SV=2"	"0.000"	""	"44"	"8"	"15"	"8"	"239"	"26.5"	"7.81"	"3628.35"	"38.20"	"6"	"7"	"other metabolic processes"	"cytoskeleton;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"204"	"ENSG00000004455"	"AK2"	"A8K6L1; B4DHH7; B4DL64; hsa:204; P54819; Q16856; Q5EB54; Q5TIF7; Q8TCY2; Q8TCY3"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"202.2"	"185.0"	"293.4"	"414.2"	"205.0"	"198.0"	"429.1"	"447.8"	"661.4"	"2961.9"	"6169.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62736"	"Actin, aortic smooth muscle OS=Homo sapiens OX=9606 GN=ACTA2 PE=1 SV=1"	"0.000"	""	"18"	"8"	"22"	"2"	"377"	"42.0"	"5.39"	"4342.06"	"38.10"	"7"	"8"	"developmental processes;other biological processes"	"extracellular matrix;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"59"	"ENSG00000107796"	"ACTA2"	"B2R8A4; hsa:59; P03996; P04108; P62736; Q6FI19"	"Myometrial relaxation and contraction pathways; Striated muscle contraction pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; 22q11.2 copy number variation syndrome; IL-18 signaling pathway; Regucalcin in proximal tubule epithelial kidney cells; Angiotensin II receptor type 1 pathway; Pleural mesothelioma; CCL18 signaling pathway; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; Comprehensive IL-17A signaling; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling"	"Smooth Muscle Contraction; NOTCH4 Intracellular Domain Regulates Transcription"	"16"	"7"	"715.3"	"743.0"	"865.8"	"1366.2"	"616.9"	"723.8"	"1317.9"	"1349.0"	"1811.0"	"3732.8"	"5233.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14168"	"MAGUK p55 subfamily member 2 OS=Homo sapiens OX=9606 GN=MPP2 PE=1 SV=3"	"0.000"	""	"23"	"9"	"17"	"8"	"576"	"64.5"	"6.77"	"3190.37"	"37.87"	"8"	"9"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	""	"Pf00595, Pf00625, Pf02828, Pf07653"	"4355"	"ENSG00000108852"	"MPP2"	"B4DGE9; B4DRJ0; B7Z3G8; E7EV80; E7EV91; E7EX01; hsa:4355; Q14168; Q53ES9; Q5CZB9; Q9BQJ2"	""	""	"0"	"0"	"160.9"	"139.1"	"207.0"	"266.1"	"167.7"	"155.3"	"439.7"	"486.9"	"869.6"	"2786.3"	"3974.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12972"	"Nuclear inhibitor of protein phosphatase 1 OS=Homo sapiens OX=9606 GN=PPP1R8 PE=1 SV=2"	"0.000"	""	"34"	"7"	"12"	"7"	"351"	"38.5"	"7.37"	"2531.17"	"37.86"	"4"	"6"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00498"	"5511"	"ENSG00000117751"	"PPP1R8"	"hsa:5511; Q12972; Q5TEJ2; Q5TEJ4; Q5TIF2; Q6PKF6; Q9UBH1; Q9UBZ0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"204.2"	"172.3"	"237.0"	"274.9"	"193.4"	"221.7"	"498.0"	"508.9"	"998.6"	"3928.2"	"4381.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61201"	"COP9 signalosome complex subunit 2 OS=Homo sapiens OX=9606 GN=COPS2 PE=1 SV=1"	"0.000"	""	"22"	"9"	"20"	"9"	"443"	"51.6"	"5.53"	"3877.86"	"37.85"	"8"	"9"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399"	"9318"	"ENSG00000166200"	"COPS2"	"hsa:9318; O88950; P61201; Q15647; Q6FGP4; Q9BY54; Q9R249; Q9UNI2; Q9UNQ5"	"Ciliary landscape"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Cargo recognition for clathrin-mediated endocytosis; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"6"	"0"	"174.2"	"164.5"	"186.4"	"253.2"	"199.9"	"265.3"	"855.1"	"977.3"	"1496.1"	"5127.4"	"8056.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60306"	"RNA helicase aquarius OS=Homo sapiens OX=9606 GN=AQR PE=1 SV=4"	"0.000"	""	"6"	"8"	"17"	"7"	"1485"	"171.2"	"6.37"	"3317.63"	"37.82"	"7"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13086, Pf13087, Pf16399"	"9716"	"ENSG00000021776"	"AQR"	"A0JP17; A5YKK3; hsa:9716; O60306; Q2YDX9; Q6IRU8; Q6PIC8"	""	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"5"	"0"	"199.0"	"204.5"	"270.6"	"305.9"	"201.5"	"216.7"	"373.9"	"416.4"	"540.5"	"1652.9"	"3020.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60934"	"Nibrin OS=Homo sapiens OX=9606 GN=NBN PE=1 SV=1"	"0.000"	""	"18"	"12"	"19"	"12"	"754"	"84.9"	"6.90"	"3726.68"	"37.77"	"9"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00498, Pf08599, Pf16508"	"4683"	"ENSG00000104320"	"NBN"	"B2R626; B2RNC5; hsa:4683; O60672; O60934; Q32NF7; Q53FM6; Q63HR6; Q7LDM2"	"miRNA regulation of DNA damage response; Homologous recombination; DDX1 as a regulatory component of the Drosha microprocessor; ATM signaling in development and disease ; Breast cancer pathway; DNA repair pathways, full network; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; DNA Damage/Telomere Stress Induced Senescence; Nonhomologous End-Joining (NHEJ); HDR through MMEJ (alt-NHEJ); Sensing of DNA Double Strand Breaks"	"29"	"0"	"612.3"	"505.4"	"681.7"	"768.4"	"581.4"	"618.8"	"1228.9"	"1326.5"	"1868.4"	"5722.9"	"9462.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23396"	"40S ribosomal protein S3 OS=Homo sapiens OX=9606 GN=RPS3 PE=1 SV=2"	"0.000"	""	"56"	"11"	"20"	"11"	"243"	"26.7"	"9.66"	"3913.67"	"37.75"	"10"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00189, Pf07650"	"6188"	"ENSG00000149273"	"RPS3"	"B2R7N5; hsa:6188; J3KN86; P23396; Q498B5; Q8NI95"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"631.5"	"545.6"	"732.7"	"904.5"	"611.0"	"639.8"	"989.7"	"1047.5"	"1375.6"	"3471.3"	"4883.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38919"	"Eukaryotic initiation factor 4A-III OS=Homo sapiens OX=9606 GN=EIF4A3 PE=1 SV=4"	"0.000"	""	"28"	"10"	"18"	"10"	"411"	"46.8"	"6.73"	"3807.12"	"37.71"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"9775"	"ENSG00000141543"	"EIF4A3"	"hsa:9775; P38919; Q15033; Q6IBQ2; Q96A18"	"TAR syndrome"	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"9"	"0"	"655.3"	"665.5"	"746.3"	"910.9"	"612.8"	"637.2"	"1040.5"	"1094.8"	"1397.3"	"4405.6"	"7567.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53582"	"Methionine aminopeptidase 1 OS=Homo sapiens OX=9606 GN=METAP1 PE=1 SV=2"	"0.000"	""	"31"	"8"	"12"	"8"	"386"	"43.2"	"7.17"	"1849.11"	"37.66"	"4"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf15801"	"23173"	"ENSG00000164024"	"METAP1"	"B4E2E6; hsa:23173; P53582"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"269.8"	"249.3"	"306.1"	"365.4"	"272.8"	"209.5"	"684.0"	"778.8"	"1105.8"	"2411.8"	"2811.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3F4"	"Serine-threonine kinase receptor-associated protein OS=Homo sapiens OX=9606 GN=STRAP PE=1 SV=1"	"0.000"	""	"36"	"8"	"16"	"8"	"350"	"38.4"	"5.12"	"3252.47"	"37.53"	"6"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00400"	"11171"	"ENSG00000023734"	"STRAP"	"B2R5S5; B4DNJ6; hsa:11171; Q5TZT4; Q9NTK0; Q9UQC8; Q9Y3F4"	"Epithelial to mesenchymal transition in colorectal cancer"	"Downregulation of TGF-beta receptor signaling"	"2"	"0"	"442.0"	"348.8"	"519.8"	"594.5"	"430.8"	"460.0"	"651.3"	"659.9"	"796.7"	"1920.5"	"3163.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13769"	"THO complex subunit 5 homolog OS=Homo sapiens OX=9606 GN=THOC5 PE=1 SV=2"	"0.000"	""	"21"	"10"	"19"	"10"	"683"	"78.5"	"6.87"	"3564.52"	"37.25"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09766"	"8563"	"ENSG00000100296"	"THOC5"	"hsa:8563; O60839; Q13769; Q9UPZ5"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Signaling by CSF1 (M-CSF) in myeloid cells"	"4"	"0"	"393.8"	"428.2"	"442.6"	"554.1"	"360.8"	"350.0"	"679.4"	"759.4"	"943.9"	"1998.8"	"2612.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CW1"	"AP-2 complex subunit mu OS=Homo sapiens OX=9606 GN=AP2M1 PE=1 SV=2"	"0.000"	""	"24"	"8"	"19"	"8"	"435"	"49.6"	"9.54"	"4395.62"	"37.23"	"7"	"6"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00928, Pf01217"	"1173"	"ENSG00000161203"	"AP2M1"	"A6NE12; D3DNT1; hsa:1173; P20172; P53679; Q96CW1"	"Synaptic vesicle pathway; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome; GDNF signaling"	"Potential therapeutics for SARS; Cargo recognition for clathrin-mediated endocytosis; VLDLR internalisation and degradation; Recycling pathway of L1; MHC class II antigen presentation; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Nef mediated downregulation of CD28 cell surface expression; Formation of annular gap junctions"	"21"	"0"	"319.3"	"287.2"	"358.6"	"498.8"	"341.4"	"538.7"	"2209.6"	"2665.8"	"2799.2"	"2836.0"	"2795.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15019"	"Septin-2 OS=Homo sapiens OX=9606 GN=SEPTIN2 PE=1 SV=1"	"0.000"	""	"37"	"11"	"19"	"11"	"361"	"41.5"	"6.60"	"3859.36"	"37.00"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00735"	"4735"	"ENSG00000168385"	"SEPTIN2"	"B4DGE8; hsa:4735; Q14132; Q15019; Q53QU3; Q8IUK9; Q96CB0"	"2q37 copy number variation syndrome"	"Anchoring of the basal body to the plasma membrane"	"2"	"0"	"823.9"	"692.9"	"895.4"	"1078.8"	"800.6"	"810.2"	"1778.8"	"1829.4"	"2598.1"	"5018.9"	"6347.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTR2"	"E3 ubiquitin-protein ligase BRE1A OS=Homo sapiens OX=9606 GN=RNF20 PE=1 SV=2"	"0.000"	""	"11"	"10"	"19"	"8"	"975"	"113.6"	"5.94"	"3468.48"	"36.79"	"9"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"56254"	"ENSG00000155827"	"RNF20"	"A7MCT5; hsa:56254; Q2TB34; Q5VTR2; Q69YL5; Q6P527; Q8N3J4; Q96JD3; Q9H9Y7; Q9HA51; Q9NUR4; Q9NWQ3; Q9NX83"	"ATM signaling in development and disease"	"E3 ubiquitin ligases ubiquitinate target proteins; RHOBTB1 GTPase cycle"	"3"	"2"	"519.6"	"423.8"	"564.0"	"650.4"	"494.4"	"500.4"	"935.8"	"944.1"	"1500.9"	"3476.3"	"4717.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92900"	"Regulator of nonsense transcripts 1 OS=Homo sapiens OX=9606 GN=UPF1 PE=1 SV=2"	"0.000"	""	"9"	"7"	"15"	"7"	"1129"	"124.3"	"6.61"	"3136.23"	"36.67"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09416, Pf13086, Pf13087, Pf18141"	"5976"	"ENSG00000005007"	"UPF1"	"hsa:5976; O00239; O43343; Q86Z25; Q92842; Q92900"	"Pathophysiological roles of DUX4 in FSHD1"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"3"	"0"	"543.7"	"488.0"	"701.3"	"889.0"	"576.5"	"567.5"	"995.6"	"1042.1"	"1363.0"	"3134.8"	"4422.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96I24"	"Far upstream element-binding protein 3 OS=Homo sapiens OX=9606 GN=FUBP3 PE=1 SV=2"	"0.000"	""	"18"	"12"	"26"	"9"	"572"	"61.6"	"8.38"	"4955.38"	"36.62"	"12"	"11"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"8939"	"ENSG00000107164"	"FUBP3"	"A3KFK8; A3KFL0; hsa:8939; Q92946; Q96I24; Q9BVB6"	""	""	"0"	"0"	"1266.7"	"1372.4"	"1295.4"	"1720.3"	"1207.1"	"1289.0"	"1892.7"	"1934.0"	"2243.6"	"4236.0"	"5960.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H078"	"Caseinolytic peptidase B protein homolog OS=Homo sapiens OX=9606 GN=CLPB PE=1 SV=1"	"0.000"	""	"18"	"8"	"12"	"8"	"707"	"78.7"	"9.01"	"1600.06"	"36.55"	"4"	"8"	"stress response;signal transduction;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf07724, Pf10431, Pf12796, Pf13857"	"81570"	"ENSG00000162129"	"CLPB"	"B4DXJ7; B4DXP7; B4DXW4; E7EWN6; F8W7P6; hsa:81570; Q8ND11; Q9H078; Q9H8Y0"	""	""	"0"	"0"	"218.7"	"189.0"	"271.9"	"313.1"	"235.3"	"229.8"	"445.1"	"473.0"	"664.3"	"2085.7"	"3513.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14152"	"Eukaryotic translation initiation factor 3 subunit A OS=Homo sapiens OX=9606 GN=EIF3A PE=1 SV=1"	"0.000"	""	"9"	"12"	"20"	"12"	"1382"	"166.5"	"6.79"	"2933.01"	"36.47"	"9"	"11"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01399"	"8661"	"ENSG00000107581"	"EIF3A"	"B1AMV5; B4DYS1; F5H335; hsa:8661; O00653; Q14152; Q15778"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"551.0"	"511.2"	"675.7"	"807.3"	"529.4"	"553.0"	"866.3"	"850.5"	"1095.3"	"2473.7"	"5788.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKY7"	"Protein CDV3 homolog OS=Homo sapiens OX=9606 GN=CDV3 PE=1 SV=1"	"0.000"	""	"34"	"7"	"15"	"7"	"258"	"27.3"	"6.40"	"3324.16"	"36.44"	"6"	"7"	""	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf15359"	"55573"	"ENSG00000091527"	"CDV3"	"B3KUC2; hsa:55573; Q96IP9; Q9UKY7"	""	""	"0"	"0"	"205.7"	"168.6"	"217.2"	"303.0"	"187.0"	"222.3"	"1250.8"	"1337.1"	"2559.6"	"5491.2"	"6037.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75400"	"Pre-mRNA-processing factor 40 homolog A OS=Homo sapiens OX=9606 GN=PRPF40A PE=1 SV=2"	"0.000"	""	"11"	"10"	"20"	"10"	"957"	"108.7"	"7.56"	"4506.42"	"36.43"	"10"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf00397, Pf01846"	"55660"	"ENSG00000196504"	"PRPF40A"	"hsa:55660; O43856; O75400; O75404; Q8TBQ1; Q9H782; Q9NWU9; Q9P0Q2; Q9Y5A8"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"1583.5"	"1373.8"	"1452.7"	"1993.8"	"1290.9"	"1368.3"	"2229.3"	"2509.4"	"3092.8"	"6628.0"	"8223.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08559"	"Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial OS=Homo sapiens OX=9606 GN=PDHA1 PE=1 SV=3"	"0.000"	""	"25"	"9"	"22"	"9"	"390"	"43.3"	"8.06"	"4832.48"	"36.33"	"9"	"8"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676"	"5160"	"ENSG00000131828"	"PDHA1"	"A5YVE9; B2R5P7; B7Z3T7; B7Z3X5; hsa:5160; P08559; Q53H41; Q5JPT8; Q9NP12; Q9UBJ8; Q9UBU0; Q9UNG4; Q9UNG5"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Lipid metabolism pathway; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Thiamine metabolic pathways; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Acetylcholine synthesis; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"15"	"0"	"1089.1"	"1097.1"	"1201.2"	"1446.0"	"983.7"	"977.4"	"1473.4"	"1553.4"	"1781.7"	"3511.2"	"4803.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09661"	"U2 small nuclear ribonucleoprotein A' OS=Homo sapiens OX=9606 GN=SNRPA1 PE=1 SV=2"	"0.000"	""	"44"	"10"	"20"	"10"	"255"	"28.4"	"8.62"	"4547.52"	"36.20"	"8"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf14580"	"6627"	"ENSG00000131876"	"SNRPA1"	"B2R5I6; hsa:6627; P09661; Q8TBD2"	"mRNA processing"	"mRNA Splicing - Major Pathway; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"3"	"0"	"1147.7"	"1315.0"	"1246.4"	"1391.4"	"1090.7"	"1100.8"	"1533.0"	"1584.0"	"1667.5"	"3295.7"	"4470.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NU22"	"Midasin OS=Homo sapiens OX=9606 GN=MDN1 PE=1 SV=2"	"0.000"	""	"3"	"15"	"21"	"15"	"5596"	"632.4"	"5.68"	"4370.71"	"36.03"	"11"	"10"	"cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07728, Pf17865, Pf17867"	"23195"	"ENSG00000112159; ENSG00000288121"	"MDN1"	"hsa:23195; O15019; Q5T794; Q9NU22"	""	""	"0"	"0"	"516.3"	"441.0"	"580.1"	"753.2"	"457.3"	"517.9"	"1025.7"	"1085.1"	"1770.4"	"4776.7"	"6148.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKF6"	"Cleavage and polyadenylation specificity factor subunit 3 OS=Homo sapiens OX=9606 GN=CPSF3 PE=1 SV=1"	"0.000"	""	"17"	"11"	"21"	"11"	"684"	"77.4"	"5.60"	"4048.62"	"36.01"	"10"	"10"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00753, Pf07521, Pf10996, Pf11718"	"51692"	"ENSG00000119203"	"CPSF3"	"hsa:51692; O14769; Q53RS2; Q96F36; Q9UKF6"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Transport of Mature mRNA Derived from an Intronless Transcript"	"6"	"0"	"509.3"	"460.1"	"604.0"	"803.5"	"518.2"	"560.2"	"920.8"	"973.1"	"1325.1"	"3495.2"	"5042.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15185"	"Prostaglandin E synthase 3 OS=Homo sapiens OX=9606 GN=PTGES3 PE=1 SV=1"	"0.000"	""	"41"	"6"	"14"	"6"	"160"	"18.7"	"4.54"	"3105.33"	"35.92"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969"	"10728"	"ENSG00000110958"	"PTGES3"	"A8K7D0; B4DHP2; B4DP11; B4DP21; hsa:10728; Q15185; Q8WU70"	"Aryl hydrocarbon receptor pathway; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Estrogen-dependent gene expression; Potential therapeutics for SARS; HSF1 activation; Aryl hydrocarbon receptor signalling; Synthesis of Prostaglandins (PG) and Thromboxanes (TX); Attenuation phase"	"11"	"0"	"1179.6"	"955.9"	"1072.7"	"1262.8"	"1074.6"	"1015.3"	"1294.4"	"1291.5"	"1247.3"	"1402.3"	"1642.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02790"	"Peptidyl-prolyl cis-trans isomerase FKBP4 OS=Homo sapiens OX=9606 GN=FKBP4 PE=1 SV=3"	"0.000"	""	"24"	"8"	"13"	"8"	"459"	"51.8"	"5.43"	"3034.89"	"35.88"	"4"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254, Pf00515"	"2288"	"ENSG00000004478"	"FKBP4"	"D3DUQ1; hsa:2288; Q02790; Q9UCP1; Q9UCV7"	"Androgen receptor signaling pathway"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Attenuation phase"	"6"	"0"	"139.6"	"153.0"	"172.8"	"233.9"	"141.2"	"155.9"	"272.3"	"285.2"	"366.7"	"1889.2"	"6186.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX01"	"SURP and G-patch domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUGP2 PE=1 SV=2"	"0.000"	""	"11"	"10"	"19"	"10"	"1082"	"120.1"	"7.28"	"3695.01"	"35.82"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"10147"	"ENSG00000064607"	"SUGP2"	"C9JI71; hsa:10147; O15071; O60369; Q5JPH7; Q8IX01; Q8WUF7"	"mRNA processing"	""	"1"	"0"	"671.3"	"550.7"	"881.6"	"947.7"	"630.5"	"688.3"	"1010.1"	"1003.7"	"1332.4"	"2442.1"	"4096.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"E9PAV3"	"Nascent polypeptide-associated complex subunit alpha, muscle-specific form OS=Homo sapiens OX=9606 GN=NACA PE=1 SV=1"	"0.000"	""	"4"	"6"	"13"	"6"	"2078"	"205.3"	"9.58"	"2006.55"	"35.79"	"4"	"6"	"transport"	"translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01849, Pf19026"	""	"ENSG00000196531"	"NACA"	"E9PAV3"	""	""	"0"	"0"	"106.2"	"83.3"	"133.3"	"203.5"	"97.6"	"108.7"	"226.3"	"258.9"	"366.2"	"1767.1"	"3624.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYP5"	"Protein ELYS OS=Homo sapiens OX=9606 GN=AHCTF1 PE=1 SV=3"	"0.000"	""	"5"	"7"	"14"	"7"	"2266"	"252.3"	"6.60"	"2507.36"	"35.66"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13934, Pf16687"	"25909"	"ENSG00000153207"	"AHCTF1"	"A6NGM0; A8MSG9; A8MZ86; hsa:25909; Q7Z4E3; Q8IZA4; Q8WYP5; Q96EH9; Q9Y4Q6"	"Gastric cancer network 2"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"8"	"0"	"302.3"	"253.8"	"296.7"	"350.1"	"252.3"	"271.7"	"455.4"	"493.1"	"654.9"	"1382.2"	"1874.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTK5"	"Obg-like ATPase 1 OS=Homo sapiens OX=9606 GN=OLA1 PE=1 SV=2"	"0.000"	""	"25"	"9"	"16"	"9"	"396"	"44.7"	"7.81"	"2620.32"	"35.66"	"7"	"9"	"other metabolic processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"translation activity;other molecular function"	"Pf01926, Pf06071"	"29789"	"ENSG00000138430"	"OLA1"	"D7EHM2; hsa:29789; Q5BJD7; Q8NCI8; Q96CU1; Q96SV2; Q9NTK5; Q9P1D3; Q9UNY9; Q9Y6G4"	""	"Platelet degranulation"	"1"	"0"	"863.5"	"745.5"	"869.0"	"1015.2"	"800.8"	"905.3"	"1500.3"	"1530.3"	"2066.7"	"5375.6"	"8365.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14625"	"Endoplasmin OS=Homo sapiens OX=9606 GN=HSP90B1 PE=1 SV=1"	"0.000"	""	"19"	"10"	"15"	"10"	"803"	"92.4"	"4.84"	"2166.07"	"35.60"	"6"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00183, Pf02518"	"7184"	"ENSG00000166598"	"HSP90B1"	"hsa:7184; P14625; Q96A97"	"Photodynamic therapy-induced unfolded protein response; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Trafficking and processing of endosomal TLR; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Interleukin-4 and Interleukin-13 signaling; Scavenging by Class A Receptors; ATF6 (ATF6-alpha) activates chaperone genes"	"11"	"0"	"509.8"	"439.2"	"533.2"	"780.6"	"474.7"	"506.8"	"779.1"	"794.4"	"964.7"	"2480.1"	"4455.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14444"	"Caprin-1 OS=Homo sapiens OX=9606 GN=CAPRIN1 PE=1 SV=2"	"0.000"	""	"13"	"9"	"19"	"9"	"709"	"78.3"	"5.25"	"3434.38"	"35.59"	"8"	"7"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12287, Pf18293"	"4076"	"ENSG00000135387"	"CAPRIN1"	"A6NMY7; D3DR06; hsa:4076; Q14444; Q15074; Q6IMN4; Q6IMN7; Q9BV09"	""	""	"0"	"0"	"261.1"	"254.1"	"343.3"	"434.0"	"290.3"	"299.6"	"534.3"	"604.6"	"1023.4"	"3148.4"	"4635.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95347"	"Structural maintenance of chromosomes protein 2 OS=Homo sapiens OX=9606 GN=SMC2 PE=1 SV=2"	"0.000"	""	"12"	"12"	"22"	"12"	"1197"	"135.6"	"8.43"	"4427.29"	"35.48"	"12"	"10"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463, Pf06470"	"10592"	"ENSG00000136824"	"SMC2"	"hsa:10592; O95347; Q6IEE0; Q9P1P2"	"Retinoblastoma gene in cancer"	"Condensation of Prophase Chromosomes; Condensation of Prometaphase Chromosomes"	"3"	"0"	"844.4"	"753.3"	"826.2"	"957.9"	"752.2"	"783.4"	"1151.9"	"1201.8"	"1494.6"	"2715.6"	"3523.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5BKZ1"	"DBIRD complex subunit ZNF326 OS=Homo sapiens OX=9606 GN=ZNF326 PE=1 SV=2"	"0.000"	""	"13"	"6"	"20"	"6"	"582"	"65.6"	"5.15"	"4640.45"	"35.46"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"284695"	"ENSG00000162664"	"ZNF326"	"A8MYX1; B4DLN0; B4E179; hsa:284695; Q5BKZ1; Q5VW93; Q5VW94; Q5VW96; Q5VW97; Q6NSA2; Q7Z638; Q7Z6C2"	""	""	"0"	"0"	"938.5"	"1059.8"	"1194.5"	"1456.5"	"1043.6"	"1025.7"	"1484.1"	"1543.6"	"1699.0"	"2615.5"	"3641.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NVY1"	"3-hydroxyisobutyryl-CoA hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HIBCH PE=1 SV=2"	"0.000"	""	"27"	"10"	"23"	"10"	"386"	"43.5"	"8.19"	"5277.74"	"35.42"	"9"	"8"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf16113"	"26275"	"ENSG00000198130"	"HIBCH"	"D3DPI4; hsa:26275; Q53GA8; Q53GF2; Q53RF7; Q53TC6; Q6NVY1; Q92931; Q9BS94"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"195.7"	"189.2"	"292.2"	"313.8"	"200.5"	"208.6"	"1266.7"	"1412.7"	"2772.4"	"8551.5"	"11767.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67809"	"Y-box-binding protein 1 OS=Homo sapiens OX=9606 GN=YBX1 PE=1 SV=3"	"0.000"	""	"33"	"7"	"14"	"5"	"324"	"35.9"	"9.88"	"2479.94"	"35.24"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00313"	"4904"	"ENSG00000065978"	"YBX1"	"hsa:4904; P16990; P16991; P67809; Q14972; Q15325; Q5FVF0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; MECP2 and associated Rett syndrome; mRNA processing; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Processing of Capped Intron-Containing Pre-mRNA; mRNA Splicing - Major Pathway; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Interferon gamma signaling; mRNA Splicing - Minor Pathway; Noncanonical activation of NOTCH3"	"10"	"2"	"443.5"	"495.8"	"445.7"	"555.6"	"398.4"	"408.7"	"574.2"	"573.6"	"621.2"	"953.4"	"1331.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15637"	"Splicing factor 1 OS=Homo sapiens OX=9606 GN=SF1 PE=1 SV=4"	"0.000"	""	"17"	"7"	"15"	"7"	"639"	"68.3"	"8.98"	"2464.39"	"35.20"	"4"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00098, Pf16275"	"7536"	"ENSG00000168066"	"SF1"	"B7Z1Q1; C9JJE2; hsa:7536; Q14818; Q14819; Q15637; Q15913; Q8IY00; Q92744; Q92745; Q969H7; Q9BW01; Q9UEI0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"378.6"	"347.0"	"466.2"	"493.9"	"392.2"	"386.3"	"703.8"	"683.2"	"956.3"	"1685.2"	"2197.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N7H5"	"RNA polymerase II-associated factor 1 homolog OS=Homo sapiens OX=9606 GN=PAF1 PE=1 SV=2"	"0.000"	""	"24"	"10"	"17"	"10"	"531"	"59.9"	"4.63"	"3075.67"	"35.19"	"8"	"9"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf03985"	"54623"	"ENSG00000006712"	"PAF1"	"hsa:54623; M0QX35; O75239; Q8N7H5; Q9H166; Q9NUU9"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"5"	"0"	"885.6"	"914.9"	"858.2"	"1023.2"	"789.9"	"801.2"	"1170.7"	"1212.9"	"1337.8"	"2220.6"	"2969.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23193"	"Transcription elongation factor A protein 1 OS=Homo sapiens OX=9606 GN=TCEA1 PE=1 SV=2"	"0.000"	""	"42"	"12"	"22"	"12"	"301"	"33.9"	"8.38"	"4888.23"	"35.19"	"11"	"8"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf07500, Pf08711"	"6917"	"ENSG00000187735"	"TCEA1"	"A6NF25; A8K339; hsa:6917; P23193; Q15563; Q6FG87"	""	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"15"	"0"	"620.4"	"511.0"	"725.2"	"840.1"	"565.6"	"632.5"	"1434.8"	"1531.1"	"2272.5"	"5368.1"	"7338.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92733"	"Proline-rich protein PRCC OS=Homo sapiens OX=9606 GN=PRCC PE=1 SV=1"	"0.000"	""	"15"	"6"	"14"	"5"	"491"	"52.4"	"5.10"	"2203.09"	"35.11"	"4"	"6"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf10253"	"5546"	"ENSG00000143294"	"PRCC"	"A8K1F7; hsa:5546; O00665; O00724; Q5SZ06; Q92733"	"Type 2 papillary renal cell carcinoma; IL-18 signaling pathway"	"mRNA Splicing - Major Pathway"	"3"	"1"	"934.9"	"891.7"	"998.4"	"1113.9"	"890.3"	"873.4"	"1191.3"	"1240.6"	"1459.6"	"2605.8"	"2945.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99613"	"Eukaryotic translation initiation factor 3 subunit C OS=Homo sapiens OX=9606 GN=EIF3C PE=1 SV=1"	"0.000"	""	"11"	"10"	"22"	"10"	"913"	"105.3"	"5.68"	"4292.29"	"35.03"	"10"	"8"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf01399, Pf05470"	"8663"	"ENSG00000184110"	"EIF3C"	"A8K7Z0; B2RXG3; B4E1D5; H3BRV0; hsa:8663; O00215; Q99613; Q9BW98"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"685.5"	"596.0"	"899.0"	"970.4"	"593.6"	"616.4"	"979.0"	"1006.9"	"1220.8"	"2708.0"	"5922.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30419"	"Glycylpeptide N-tetradecanoyltransferase 1 OS=Homo sapiens OX=9606 GN=NMT1 PE=1 SV=2"	"0.000"	""	"22"	"9"	"17"	"8"	"496"	"56.8"	"7.80"	"3134.02"	"35.02"	"8"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01233, Pf02799"	"4836"	"ENSG00000136448"	"NMT1"	"A8K7C1; hsa:4836; P30419; Q9UE09"	""	"Inactivation, recovery and regulation of the phototransduction cascade; Late Phase of HIV Life Cycle; Activation, myristolyation of BID and translocation to mitochondria"	"3"	"1"	"443.5"	"374.9"	"517.0"	"553.6"	"394.7"	"422.8"	"1033.2"	"1083.1"	"1955.6"	"3984.3"	"3699.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34932"	"Heat shock 70 kDa protein 4 OS=Homo sapiens OX=9606 GN=HSPA4 PE=1 SV=4"	"0.000"	""	"16"	"14"	"26"	"12"	"840"	"94.3"	"5.19"	"5739.19"	"34.85"	"14"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00012"	"3308"	"ENSG00000170606"	"HSPA4"	"hsa:3308; O95756; P34932; Q2TAL4; Q9BUK9"	"Parkin-ubiquitin proteasomal system pathway"	"Regulation of HSF1-mediated heat shock response"	"2"	"2"	"1388.1"	"1260.1"	"1708.6"	"2180.3"	"1338.6"	"1409.4"	"1930.9"	"1932.2"	"2238.1"	"4414.9"	"6392.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2W2"	"WW domain-binding protein 11 OS=Homo sapiens OX=9606 GN=WBP11 PE=1 SV=1"	"0.000"	""	"15"	"7"	"14"	"7"	"641"	"70.0"	"8.38"	"2318.00"	"34.83"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09429"	"51729"	"ENSG00000084463"	"WBP11"	"hsa:51729; Q96AY8; Q9Y2W2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"412.8"	"397.3"	"465.6"	"615.8"	"463.3"	"421.9"	"653.0"	"722.7"	"922.2"	"2068.1"	"2253.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CX2"	"BTB/POZ domain-containing protein KCTD12 OS=Homo sapiens OX=9606 GN=KCTD12 PE=1 SV=1"	"0.000"	""	"36"	"9"	"18"	"9"	"325"	"35.7"	"5.64"	"3519.26"	"34.77"	"9"	"9"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf02214"	"115207"	"ENSG00000178695"	"KCTD12"	"hsa:115207; Q96CX2"	""	""	"0"	"0"	"221.0"	"203.3"	"259.8"	"320.6"	"218.1"	"233.6"	"451.2"	"487.6"	"742.4"	"2517.3"	"3797.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29966"	"Myristoylated alanine-rich C-kinase substrate OS=Homo sapiens OX=9606 GN=MARCKS PE=1 SV=4"	"0.000"	""	"26"	"7"	"15"	"7"	"332"	"31.5"	"4.45"	"3233.26"	"34.69"	"7"	"7"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"4082"	"ENSG00000277443"	"MARCKS"	"E1P560; hsa:4082; P29966; Q2LA83; Q5TDB7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway"	"Acetylcholine regulates insulin secretion"	"2"	"0"	"297.8"	"243.2"	"320.3"	"399.6"	"266.8"	"278.8"	"902.9"	"947.4"	"1913.9"	"5179.9"	"6112.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13242"	"Serine/arginine-rich splicing factor 9 OS=Homo sapiens OX=9606 GN=SRSF9 PE=1 SV=1"	"0.000"	""	"38"	"10"	"23"	"9"	"221"	"25.5"	"8.65"	"4047.32"	"34.47"	"10"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"8683"	"ENSG00000111786"	"SRSF9"	"hsa:8683; Q13242; Q52LD1"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"1055.2"	"1060.4"	"1033.7"	"1523.8"	"939.0"	"852.1"	"1357.5"	"1443.7"	"1465.3"	"2367.2"	"3104.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SRE5"	"Nucleoporin NUP188 homolog OS=Homo sapiens OX=9606 GN=NUP188 PE=1 SV=1"	"0.000"	""	"6"	"8"	"16"	"8"	"1749"	"195.9"	"6.73"	"3953.62"	"34.36"	"7"	"7"	"transport"	"cytosol;nucleus"	"other molecular function"	"Pf10487"	"23511"	"ENSG00000095319"	"NUP188"	"hsa:23511; Q14675; Q2TA87; Q5SRE5; Q7Z3K8; Q8IWF1"	""	"Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; SUMOylation of chromatin organization proteins; HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"376.4"	"325.5"	"376.1"	"429.4"	"329.9"	"319.5"	"553.5"	"589.1"	"746.1"	"1680.0"	"2230.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83731"	"60S ribosomal protein L24 OS=Homo sapiens OX=9606 GN=RPL24 PE=1 SV=1"	"0.000"	""	"36"	"6"	"18"	"6"	"157"	"17.8"	"11.25"	"3149.03"	"34.35"	"5"	"6"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01246"	"6152"	"ENSG00000114391"	"RPL24"	"B2R4Y3; hsa:6152; P38663; P83731; Q6IBS3"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"1127.5"	"1150.5"	"1291.5"	"1609.4"	"1166.9"	"1124.8"	"1821.2"	"1868.4"	"2358.4"	"4916.2"	"7917.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13247"	"Serine/arginine-rich splicing factor 6 OS=Homo sapiens OX=9606 GN=SRSF6 PE=1 SV=2"	"0.000"	""	"22"	"8"	"21"	"4"	"344"	"39.6"	"11.43"	"3520.07"	"34.28"	"7"	"8"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6431"	"ENSG00000124193"	"SRSF6"	"B7Z6J3; E1P5W6; hsa:6431; Q13244; Q13245; Q13247; Q96J06; Q9UJB8; Q9Y3N7"	"mRNA processing"	"RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"7"	"4"	"2050.3"	"1725.1"	"2268.9"	"2802.3"	"1843.4"	"1578.9"	"2445.7"	"2458.6"	"2518.6"	"4001.6"	"6216.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15007"	"Pre-mRNA-splicing regulator WTAP OS=Homo sapiens OX=9606 GN=WTAP PE=1 SV=2"	"0.000"	""	"26"	"7"	"15"	"7"	"396"	"44.2"	"5.19"	"2945.63"	"34.23"	"7"	"7"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf17098"	"9589"	"ENSG00000146457"	"WTAP"	"hsa:9589; Q15007; Q5TCL8; Q5TCL9; Q96T28; Q9BYJ7; Q9H4E2"	""	"Processing of Capped Intron-Containing Pre-mRNA"	"1"	"0"	"361.2"	"260.9"	"448.5"	"485.9"	"325.0"	"344.5"	"519.1"	"516.7"	"629.8"	"1396.4"	"3026.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UN15"	"Pre-mRNA 3'-end-processing factor FIP1 OS=Homo sapiens OX=9606 GN=FIP1L1 PE=1 SV=1"	"0.000"	""	"14"	"6"	"20"	"6"	"594"	"66.5"	"5.59"	"3719.64"	"34.10"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf05182"	"81608"	"ENSG00000145216"	"FIP1L1"	"B4DIR3; G3XAD6; hsa:81608; Q0VGE0; Q499Y4; Q49AU3; Q6UN15; Q7Z608; Q8WVN3; Q96F80; Q9H077"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Signaling by cytosolic PDGFRA and PDGFRB fusion proteins"	"6"	"0"	"557.1"	"462.9"	"533.3"	"615.2"	"466.9"	"485.4"	"640.7"	"666.5"	"812.8"	"1533.3"	"1972.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43583"	"Density-regulated protein OS=Homo sapiens OX=9606 GN=DENR PE=1 SV=2"	"0.000"	""	"30"	"4"	"12"	"4"	"198"	"22.1"	"5.30"	"1407.28"	"34.06"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"nucleic acid binding activity"	"Pf01253"	"8562"	"ENSG00000139726"	"DENR"	"hsa:8562; O43583; Q9H3U6; Q9UKZ0"	""	""	"0"	"0"	"164.5"	"135.9"	"194.0"	"210.4"	"134.6"	"161.5"	"644.8"	"752.5"	"1358.0"	"3087.7"	"3065.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12769"	"Nuclear pore complex protein Nup160 OS=Homo sapiens OX=9606 GN=NUP160 PE=1 SV=3"	"0.000"	""	"7"	"7"	"17"	"7"	"1436"	"162.0"	"5.50"	"3397.85"	"33.97"	"6"	"7"	"other metabolic processes;transport;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf11715"	"23279"	"ENSG00000030066"	"NUP160"	"B4DYE8; B4E2J9; hsa:23279; Q08AD3; Q12769; Q7Z5X6; Q96GB3; Q9H660"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"35"	"0"	"399.0"	"385.4"	"395.7"	"427.9"	"335.7"	"357.8"	"547.6"	"547.0"	"646.8"	"1007.3"	"1248.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QC0"	"Serine/threonine-protein phosphatase 1 regulatory subunit 10 OS=Homo sapiens OX=9606 GN=PPP1R10 PE=1 SV=1"	"0.000"	""	"12"	"9"	"17"	"9"	"940"	"99.0"	"9.17"	"3830.73"	"33.93"	"7"	"8"	"transport;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf08711"	"5514"	"ENSG00000204569; ENSG00000206489; ENSG00000227804; ENSG00000230995; ENSG00000231737; ENSG00000235291; ENSG00000238104"	"PPP1R10"	"hsa:5514; O00405; Q96QC0"	""	""	"0"	"0"	"670.8"	"469.5"	"683.0"	"769.5"	"589.2"	"572.9"	"798.9"	"809.5"	"1012.7"	"1759.1"	"2077.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43795"	"Unconventional myosin-Ib OS=Homo sapiens OX=9606 GN=MYO1B PE=1 SV=3"	"0.000"	""	"8"	"7"	"17"	"6"	"1136"	"131.9"	"9.38"	"3065.54"	"33.92"	"6"	"7"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4430"	"ENSG00000128641"	"MYO1B"	"hsa:4430; O43794; O43795; Q7Z6L5"	""	""	"0"	"0"	"307.5"	"282.1"	"324.3"	"469.5"	"320.1"	"311.1"	"660.2"	"715.8"	"1064.4"	"2318.9"	"3016.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13647"	"Keratin, type II cytoskeletal 5 OS=Homo sapiens OX=9606 GN=KRT5 PE=1 SV=3"	"0.000"	""	"15"	"10"	"20"	"6"	"590"	"62.3"	"7.74"	"2858.32"	"33.82"	"7"	"10"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"bone, tooth or skin structural activity;cytoskeletal activity;other molecular function"	"Pf00038, Pf16208"	"3852"	"ENSG00000186081"	"KRT5"	"hsa:3852; P13647; Q6PI71; Q6UBJ0; Q8TA91"	""	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"3"	"0"	"162.1"	"166.0"	"976.6"	"116.8"	"41.2"	"134.8"	"339.4"	"307.7"	"277.5"	"453.2"	"818.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43175"	"D-3-phosphoglycerate dehydrogenase OS=Homo sapiens OX=9606 GN=PHGDH PE=1 SV=4"	"0.000"	""	"20"	"7"	"14"	"7"	"533"	"56.6"	"6.71"	"2483.09"	"33.76"	"5"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00389, Pf02826, Pf19304"	"26227"	"ENSG00000092621"	"PHGDH"	"B2RD08; hsa:26227; O43175; Q5SZU3; Q9BQ01"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"5"	"0"	"429.2"	"360.6"	"510.0"	"622.4"	"391.0"	"468.7"	"1080.1"	"1145.6"	"1475.9"	"3493.1"	"5159.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34897"	"Serine hydroxymethyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=SHMT2 PE=1 SV=3"	"0.000"	""	"20"	"11"	"21"	"10"	"504"	"56.0"	"8.53"	"3899.81"	"33.72"	"10"	"10"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6472"	"ENSG00000182199"	"SHMT2"	"B7Z9F1; E7EQ19; E7EU43; hsa:6472; O00740; P34897; Q8N1A5"	"Glycine metabolism; Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders"	"RHOG GTPase cycle; Metabolism of folate and pterines"	"11"	"1"	"937.3"	"1024.7"	"950.3"	"1231.4"	"868.4"	"853.1"	"1342.9"	"1407.6"	"1617.4"	"2956.7"	"4205.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57721"	"Poly(rC)-binding protein 3 OS=Homo sapiens OX=9606 GN=PCBP3 PE=1 SV=2"	"0.000"	""	"18"	"6"	"14"	"1"	"371"	"39.4"	"8.07"	"2699.30"	"33.69"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"54039"	"ENSG00000183570"	"PCBP3"	"A8MPS2; A8MQ26; B7WNN9; B7WPC1; hsa:54039; P57721; Q8N9K6; Q96EP6"	""	""	"0"	"0"	"29.1"	"28.5"	"43.3"	"51.1"	"31.2"	"22.0"	"61.8"	"67.1"	"87.0"	"244.6"	"367.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14936"	"Peripheral plasma membrane protein CASK OS=Homo sapiens OX=9606 GN=CASK PE=1 SV=3"	"0.000"	""	"10"	"8"	"15"	"8"	"926"	"105.1"	"6.43"	"2924.17"	"33.64"	"7"	"8"	"cell adhesion;protein metabolism;other metabolic processes;transport;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00595, Pf00625, Pf02828"	"8573"	"ENSG00000147044"	"CASK"	"A6NES1; B7ZKY0; hsa:8573; O14936; O43215; Q17RI4; Q59HA0; Q5VT16; Q5VT17; Q5VT18; Q5VT19; Q66T42; Q9BYH6; Q9NYB2; Q9NYB3"	"Parkin-ubiquitin proteasomal system pathway; Splicing factor NOVA regulated synaptic proteins"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Assembly and cell surface presentation of NMDA receptors; Nephrin family interactions; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle; Syndecan interactions"	"9"	"0"	"206.8"	"207.5"	"261.0"	"311.2"	"223.1"	"222.9"	"523.6"	"571.6"	"1003.9"	"2664.5"	"3281.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00610"	"Clathrin heavy chain 1 OS=Homo sapiens OX=9606 GN=CLTC PE=1 SV=5"	"0.000"	""	"6"	"9"	"19"	"9"	"1675"	"191.5"	"5.69"	"3967.93"	"33.53"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00637, Pf01394, Pf09268, Pf13838"	"1213"	"ENSG00000141367"	"CLTC"	"D3DU00; hsa:1213; Q00610; Q6N0A0; Q86TF2"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; Ebola virus infection in host; Fragile X syndrome; 7q11.23 copy number variation syndrome; Complement and coagulation cascades"	"ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer; Recycling pathway of L1; MHC class II antigen presentation; RHOV GTPase cycle; Lysosome Vesicle Biogenesis; RHOU GTPase cycle; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"25"	"0"	"492.4"	"514.2"	"509.6"	"730.5"	"476.9"	"447.3"	"794.7"	"878.0"	"1078.8"	"2038.0"	"2574.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07021"	"Complement component 1 Q subcomponent-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=C1QBP PE=1 SV=1"	"0.000"	""	"34"	"6"	"13"	"6"	"282"	"31.3"	"4.84"	"2473.10"	"33.51"	"4"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;nucleic acid binding activity;other molecular function"	"Pf02330"	"708"	"ENSG00000108561"	"C1QBP"	"hsa:708; Q07021; Q2HXR8; Q9NNY8"	"Complement system; Mesodermal commitment pathway; Ebola virus infection in host"	"RHOC GTPase cycle; RHOA GTPase cycle; Intrinsic Pathway of Fibrin Clot Formation; Apoptotic factor-mediated response; Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function"	"8"	"0"	"654.0"	"523.5"	"651.7"	"768.2"	"567.1"	"603.0"	"756.0"	"762.6"	"861.4"	"1392.4"	"1995.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49006"	"MARCKS-related protein OS=Homo sapiens OX=9606 GN=MARCKSL1 PE=1 SV=2"	"0.000"	""	"37"	"5"	"14"	"5"	"195"	"19.5"	"4.67"	"2344.16"	"33.51"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02063"	"65108"	"ENSG00000175130"	"MARCKSL1"	"D3DPQ0; hsa:65108; P49006; Q5TEE6; Q6NXS5"	""	""	"0"	"0"	"107.1"	"98.9"	"161.9"	"170.1"	"104.6"	"112.6"	"408.8"	"441.5"	"920.2"	"3004.0"	"3633.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45973"	"Chromobox protein homolog 5 OS=Homo sapiens OX=9606 GN=CBX5 PE=1 SV=1"	"0.000"	""	"39"	"6"	"15"	"5"	"191"	"22.2"	"5.86"	"2957.18"	"33.46"	"6"	"6"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"23468"	"ENSG00000094916"	"CBX5"	"B2R8T9; hsa:23468; P45973"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; 22q11.2 copy number variation syndrome"	"Factors involved in megakaryocyte development and platelet production; SUMOylation of chromatin organization proteins; Transcriptional Regulation by E2F6"	"5"	"1"	"332.3"	"334.6"	"355.5"	"498.9"	"298.7"	"290.8"	"836.4"	"846.7"	"1354.9"	"5108.4"	"7709.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49591"	"Serine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=SARS1 PE=1 SV=3"	"0.000"	""	"28"	"12"	"21"	"12"	"514"	"58.7"	"6.43"	"4345.20"	"33.43"	"10"	"9"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00587, Pf02403"	"6301"	"ENSG00000031698"	"SARS1"	"B2R6Y9; hsa:6301; P49591; Q5T5C8; Q9NSE3"	"VEGFA-VEGFR2 signaling"	"Selenocysteine synthesis; Cytosolic tRNA aminoacylation"	"3"	"0"	"642.1"	"646.8"	"695.7"	"809.3"	"637.5"	"619.0"	"1723.6"	"1853.7"	"3222.3"	"6775.7"	"7791.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13123"	"Protein Red OS=Homo sapiens OX=9606 GN=IK PE=1 SV=3"	"0.000"	""	"23"	"12"	"22"	"12"	"557"	"65.6"	"6.64"	"3832.09"	"33.18"	"10"	"10"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07807, Pf07808"	"3550"	"ENSG00000113141"	"IK"	"hsa:3550; Q13123; Q6IPD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"2399.0"	"2092.8"	"2321.4"	"2594.9"	"1913.9"	"2096.9"	"2706.8"	"2809.7"	"3073.2"	"4752.7"	"5590.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DME0"	"Protein SETSIP OS=Homo sapiens OX=9606 GN=SETSIP PE=1 SV=1"	"0.000"	""	"16"	"5"	"16"	"5"	"302"	"34.9"	"4.31"	"3256.97"	"33.12"	"5"	"5"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"646817"	"ENSG00000230667"	"SETSIP"	"hsa:646817; P0DME0"	""	""	"0"	"0"	"771.2"	"1122.5"	"740.4"	"1228.6"	"751.9"	"725.9"	"1368.7"	"1598.6"	"1894.1"	"3165.6"	"3614.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04917"	"14-3-3 protein eta OS=Homo sapiens OX=9606 GN=YWHAH PE=1 SV=4"	"0.000"	""	"27"	"6"	"19"	"3"	"246"	"28.2"	"4.84"	"2939.98"	"33.03"	"4"	"6"	"other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00244"	"7533"	"ENSG00000128245"	"YWHAH"	"hsa:7533; Q04917"	"Cell cycle; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"11"	"0"	"312.3"	"291.8"	"302.9"	"355.6"	"288.2"	"281.3"	"481.5"	"465.8"	"574.1"	"1118.8"	"1460.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GS9"	"U4/U6.U5 tri-snRNP-associated protein 2 OS=Homo sapiens OX=9606 GN=USP39 PE=1 SV=2"	"0.000"	""	"26"	"11"	"18"	"10"	"565"	"65.3"	"8.91"	"3153.10"	"32.96"	"9"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00443, Pf02148"	"10713"	"ENSG00000168883"	"USP39"	"A8K086; B3KM40; B4DHT4; D6W5L4; G5E9H0; hsa:10713; Q53GS9; Q6NX47; Q96RK9; Q9BV89; Q9H381; Q9P050; Q9Y310"	""	"mRNA Splicing - Major Pathway"	"1"	"1"	"608.8"	"527.0"	"620.2"	"690.6"	"527.2"	"527.9"	"852.8"	"912.2"	"1165.4"	"2490.4"	"3056.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49454"	"Centromere protein F OS=Homo sapiens OX=9606 GN=CENPF PE=1 SV=3"	"0.000"	""	"5"	"13"	"23"	"12"	"3114"	"357.3"	"5.10"	"5066.84"	"32.70"	"13"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10473, Pf10481, Pf10490"	"1063"	"ENSG00000117724"	"CENPF"	"hsa:1063; P49454; Q13171; Q13246; Q5VVM7"	"Gastric cancer network 1; Ciliopathies"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Polo-like kinase mediated events"	"9"	"0"	"523.2"	"475.8"	"605.7"	"672.1"	"504.1"	"501.0"	"778.7"	"813.1"	"1016.6"	"2233.1"	"2986.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08752"	"Peptidyl-prolyl cis-trans isomerase D OS=Homo sapiens OX=9606 GN=PPID PE=1 SV=3"	"0.000"	""	"30"	"10"	"12"	"10"	"370"	"40.7"	"7.21"	"1238.28"	"32.68"	"3"	"9"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160, Pf13176"	"5481"	"ENSG00000171497"	"PPID"	"B2R9V2; hsa:5481; Q08752"	"Alzheimer's disease and miRNA effects; NO/cGMP/PKG mediated neuroprotection; Alzheimer's disease"	"ESR-mediated signaling"	"4"	"0"	"201.1"	"193.1"	"250.2"	"310.4"	"200.7"	"209.4"	"515.3"	"557.5"	"905.4"	"3261.7"	"5077.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VTL8"	"Pre-mRNA-splicing factor 38B OS=Homo sapiens OX=9606 GN=PRPF38B PE=1 SV=1"	"0.000"	""	"14"	"6"	"16"	"6"	"546"	"64.4"	"10.54"	"3096.26"	"32.67"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371"	"55119"	"ENSG00000134186"	"PRPF38B"	"hsa:55119; Q05DD6; Q32Q58; Q5VTL8; Q5VTL9; Q6PK39; Q7Z6E2; Q86WF3; Q8IWG9; Q9NW40"	""	""	"0"	"0"	"630.3"	"588.4"	"652.5"	"864.0"	"568.8"	"597.1"	"868.2"	"916.6"	"1152.0"	"2530.5"	"3160.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q32MZ4"	"Leucine-rich repeat flightless-interacting protein 1 OS=Homo sapiens OX=9606 GN=LRRFIP1 PE=1 SV=2"	"0.000"	""	"12"	"8"	"14"	"8"	"808"	"89.2"	"4.65"	"2788.09"	"32.63"	"6"	"8"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09738"	"9208"	"ENSG00000124831"	"LRRFIP1"	"E9PGZ2; hsa:9208; O75766; O75799; Q32MZ4; Q32MZ5; Q53T49; Q6PKG2; Q9Y607"	"IL-18 signaling pathway; 2q37 copy number variation syndrome"	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"5"	"0"	"227.0"	"192.3"	"261.6"	"279.8"	"219.3"	"219.0"	"493.7"	"537.2"	"868.4"	"2689.7"	"3692.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UN86"	"Ras GTPase-activating protein-binding protein 2 OS=Homo sapiens OX=9606 GN=G3BP2 PE=1 SV=2"	"0.000"	""	"16"	"7"	"15"	"7"	"482"	"54.1"	"5.55"	"2088.83"	"32.63"	"5"	"7"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"9908"	"ENSG00000138757"	"G3BP2"	"A8K6X1; hsa:9908; O60606; O75149; Q9UN86; Q9UPA1"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"632.0"	"533.1"	"660.0"	"885.2"	"562.9"	"610.6"	"892.5"	"947.8"	"1184.4"	"2646.1"	"4147.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00148"	"ATP-dependent RNA helicase DDX39A OS=Homo sapiens OX=9606 GN=DDX39A PE=1 SV=2"	"0.000"	""	"19"	"8"	"17"	"1"	"427"	"49.1"	"5.68"	"2980.52"	"32.56"	"7"	"8"	"RNA metabolism OR transcription;other metabolic processes;transport"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"10212"	"ENSG00000123136"	"DDX39A"	"B1Q2N1; hsa:10212; O00148; Q8N5M0; Q9BVP6; Q9H5W0"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"39.7"	"24.1"	"51.6"	"56.0"	"40.0"	"39.7"	"61.8"	"58.9"	"91.3"	"201.9"	"343.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63092"	"Guanine nucleotide-binding protein G(s) subunit alpha isoforms short OS=Homo sapiens OX=9606 GN=GNAS PE=1 SV=1"	"0.000"	""	"31"	"9"	"15"	"8"	"394"	"45.6"	"5.82"	"2531.43"	"32.53"	"7"	"8"	"cell adhesion;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00503"	"2778"	"ENSG00000087460"	"GNAS"	"A6NI00; E1P5G5; hsa:2778; P04895; P63092; Q12927; Q14433; Q32P26; Q5JWD2; Q5JWD4; Q5JWD5; Q6NR75; Q6NXS0; Q8TBC0; Q96H70"	"Thyroid stimulating hormone (TSH) signaling pathway; Endothelin pathways; Corticotropin-releasing hormone signaling pathway; Common pathways underlying drug addiction; Myometrial relaxation and contraction pathways; G protein signaling pathways; Thermogenesis; Hippo signaling regulation pathways; Purinergic signaling; GPR143 in melanocytes and retinal pigment epithelium cells; Prostaglandin and leukotriene metabolism in senescence ; Primary ovarian insufficiency; Prostaglandin and leukotriene metabolism in senescence ; Calcium regulation in cardiac cells; Estrogen signaling pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"G alpha (i) signalling events; G alpha (z) signalling events; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Prostacyclin signalling through prostacyclin receptor; Glucagon-type ligand receptors; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation in glucagon signalling; Hedgehog 'off' state"	"28"	"1"	"202.9"	"188.4"	"280.2"	"326.8"	"204.1"	"201.2"	"431.5"	"457.1"	"697.7"	"2817.6"	"4308.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5UIP0"	"Telomere-associated protein RIF1 OS=Homo sapiens OX=9606 GN=RIF1 PE=1 SV=2"	"0.000"	""	"5"	"9"	"15"	"9"	"2472"	"274.3"	"5.52"	"2917.36"	"32.49"	"8"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	""	"Pf12231"	"55183"	"ENSG00000080345"	"RIF1"	"A6NC27; C9JBR1; hsa:55183; Q5H9R3; Q5UIP0; Q5UIP2; Q66YK6; Q6PRU2; Q8TE94; Q99772; Q9H830; Q9H9B9; Q9NVP5; Q9Y4R4"	"ATM signaling in development and disease ; 10q11.21q11.23 copy number variation syndrome"	"Nonhomologous End-Joining (NHEJ)"	"3"	"0"	"496.2"	"402.7"	"555.3"	"597.8"	"472.0"	"500.1"	"781.8"	"771.3"	"1118.5"	"2149.3"	"2658.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61981"	"14-3-3 protein gamma OS=Homo sapiens OX=9606 GN=YWHAG PE=1 SV=2"	"0.000"	""	"21"	"6"	"21"	"1"	"247"	"28.3"	"4.89"	"4120.65"	"32.46"	"6"	"6"	"transport;signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00244"	"7532"	"ENSG00000170027"	"YWHAG"	"hsa:7532; O70457; P35214; P61981; Q6FH52; Q9UDP2; Q9UN99"	"Cell cycle; Prolactin signaling pathway; Myometrial relaxation and contraction pathways; Disruption of postsynaptic signaling by CNV; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of localization of FOXO transcription factors; TP53 Regulates Metabolic Genes; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways; Activation of BAD and translocation to mitochondria"	"21"	"0"	"146.6"	"133.3"	"136.1"	"142.4"	"128.3"	"145.9"	"173.6"	"171.2"	"200.7"	"272.0"	"317.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04637"	"Eukaryotic translation initiation factor 4 gamma 1 OS=Homo sapiens OX=9606 GN=EIF4G1 PE=1 SV=4"	"0.000"	""	"6"	"8"	"18"	"7"	"1599"	"175.4"	"5.33"	"3179.22"	"32.43"	"7"	"7"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02020, Pf02847, Pf02854"	"1981"	"ENSG00000114867"	"EIF4G1"	"D3DNT2; D3DNT4; D3DNT5; E9PFM1; G5E9S1; hsa:1981; O43177; O95066; Q04637; Q5HYG0; Q6ZN21; Q8N102"	"Translation factors; VEGFA-VEGFR2 signaling; Acute viral myocarditis; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Pleural mesothelioma"	"AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Deadenylation of mRNA; ISG15 antiviral mechanism; mTORC1-mediated signalling"	"18"	"1"	"875.1"	"838.2"	"919.7"	"1090.0"	"811.0"	"843.5"	"1380.0"	"1392.9"	"1767.3"	"5528.1"	"7420.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94973"	"AP-2 complex subunit alpha-2 OS=Homo sapiens OX=9606 GN=AP2A2 PE=1 SV=2"	"0.000"	""	"11"	"9"	"19"	"6"	"939"	"103.9"	"6.96"	"3088.07"	"32.28"	"7"	"9"	"transport"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01602, Pf02296, Pf02883"	"161"	"ENSG00000183020"	"AP2A2"	"hsa:161; O75403; O94973; Q53ET1; Q96SI8"	"Synaptic vesicle pathway; GABA receptor signaling; mBDNF and proBDNF regulation of GABA neurotransmission"	"Neutrophil degranulation; MHC class II antigen presentation; Potential therapeutics for SARS; Recycling pathway of L1; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; LDL clearance; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"17"	"0"	"136.3"	"123.9"	"183.1"	"225.5"	"165.9"	"248.6"	"1205.9"	"1339.7"	"1607.6"	"1817.5"	"1930.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94842"	"TOX high mobility group box family member 4 OS=Homo sapiens OX=9606 GN=TOX4 PE=1 SV=1"	"0.000"	""	"17"	"8"	"15"	"8"	"621"	"66.2"	"5.06"	"2648.39"	"32.28"	"7"	"8"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505"	"9878"	"ENSG00000092203"	"TOX4"	"B4DPY8; B4DSM0; E7EV69; hsa:9878; O94842"	""	""	"0"	"0"	"449.5"	"378.5"	"442.2"	"548.5"	"404.6"	"359.6"	"680.2"	"726.4"	"895.9"	"2262.4"	"2839.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y314"	"Nitric oxide synthase-interacting protein OS=Homo sapiens OX=9606 GN=NOSIP PE=1 SV=1"	"0.000"	""	"36"	"7"	"14"	"7"	"301"	"33.2"	"8.82"	"2428.18"	"32.16"	"5"	"7"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf15906"	"51070"	"ENSG00000142546"	"NOSIP"	"hsa:51070; Q96FD2; Q9Y314"	""	"NOSIP mediated eNOS trafficking"	"1"	"0"	"452.5"	"445.1"	"544.4"	"601.2"	"482.0"	"479.7"	"834.5"	"929.3"	"1247.5"	"1799.3"	"2012.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26641"	"Elongation factor 1-gamma OS=Homo sapiens OX=9606 GN=EEF1G PE=1 SV=3"	"0.000"	""	"21"	"10"	"22"	"10"	"437"	"50.1"	"6.67"	"4181.28"	"32.10"	"10"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf00043, Pf00647, Pf02798"	"1937"	"ENSG00000254772"	"EEF1G"	"B4DTG2; hsa:1937; P26641; Q6PJ62; Q6PK31; Q96CU2; Q9P196"	"Translation factors"	"Signaling by ALK fusions and activated point mutants; Eukaryotic Translation Elongation"	"3"	"0"	"1246.5"	"1083.6"	"1292.5"	"1564.2"	"1125.2"	"1066.3"	"1912.7"	"1981.9"	"2527.9"	"7142.7"	"9095.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04843"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1 OS=Homo sapiens OX=9606 GN=RPN1 PE=1 SV=1"	"0.000"	""	"11"	"5"	"15"	"5"	"607"	"68.5"	"6.38"	"3107.04"	"32.08"	"4"	"5"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cell component"	""	"Pf04597"	"6184"	"ENSG00000163902"	"RPN1"	"B2R5Z0; D3DNB6; hsa:6184; P04843; Q68DT1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	"223.8"	"220.5"	"280.7"	"339.5"	"229.7"	"239.3"	"428.3"	"454.3"	"658.0"	"1865.0"	"2870.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14839"	"Chromodomain-helicase-DNA-binding protein 4 OS=Homo sapiens OX=9606 GN=CHD4 PE=1 SV=2"	"0.000"	""	"6"	"9"	"14"	"9"	"1912"	"217.9"	"5.86"	"2070.06"	"32.07"	"6"	"8"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf00628, Pf06461, Pf06465, Pf08073, Pf08074"	"1108"	"ENSG00000111642"	"CHD4"	"hsa:1108; Q14839; Q8IXZ5"	"Rett syndrome causing genes; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation; NGF-stimulated transcription"	"9"	"0"	"489.2"	"382.1"	"529.0"	"626.4"	"427.5"	"461.5"	"756.6"	"812.9"	"1135.6"	"3309.8"	"3571.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75937"	"DnaJ homolog subfamily C member 8 OS=Homo sapiens OX=9606 GN=DNAJC8 PE=1 SV=2"	"0.000"	""	"47"	"11"	"14"	"11"	"253"	"29.8"	"9.06"	"1944.33"	"32.07"	"5"	"9"	""	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226"	"22826"	"ENSG00000126698; ENSG00000285317"	"DNAJC8"	"B4DUU4; D3DPM0; hsa:22826; O75937; Q6IBA4; Q8N4Z5; Q9P051; Q9P067"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"811.8"	"591.4"	"792.0"	"891.7"	"774.8"	"824.0"	"1741.0"	"1915.8"	"2601.3"	"4326.0"	"5296.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13185"	"Chromobox protein homolog 3 OS=Homo sapiens OX=9606 GN=CBX3 PE=1 SV=4"	"0.000"	""	"39"	"6"	"12"	"4"	"183"	"20.8"	"5.33"	"2512.93"	"32.06"	"4"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf01393"	"11335"	"ENSG00000122565"	"CBX3"	"hsa:11335; Q13185; Q96CD7; Q99409; Q9BVS3; Q9P0Z6"	"Exercise-induced circadian regulation; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"RNA Polymerase I Promoter Escape; Transcriptional Regulation by E2F6; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression"	"6"	"2"	"328.7"	"342.9"	"362.6"	"507.5"	"282.3"	"310.5"	"454.8"	"471.0"	"573.0"	"1613.9"	"4936.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12904"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 OS=Homo sapiens OX=9606 GN=AIMP1 PE=1 SV=2"	"0.000"	""	"36"	"9"	"18"	"9"	"312"	"34.3"	"8.43"	"4263.79"	"31.91"	"9"	"7"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01588"	"9255"	"ENSG00000164022"	"AIMP1"	"B3KTR2; B4E1S7; hsa:9255; Q12904; Q6FG28; Q96CQ9"	"Ciliary landscape"	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"3"	"0"	"443.1"	"392.1"	"475.5"	"552.9"	"401.8"	"427.4"	"1016.4"	"1093.3"	"1654.6"	"5029.0"	"6394.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49736"	"DNA replication licensing factor MCM2 OS=Homo sapiens OX=9606 GN=MCM2 PE=1 SV=4"	"0.000"	""	"13"	"8"	"15"	"8"	"904"	"101.8"	"5.52"	"2528.24"	"31.74"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00493, Pf12619, Pf14551, Pf17207, Pf17855"	"4171"	"ENSG00000073111"	"MCM2"	"hsa:4171; P49736; Q14577; Q15023; Q8N2V1; Q969W7; Q96AE1; Q9BRM7"	"Cell cycle; Ciliary landscape; G1 to S cell cycle control; DNA replication; 1p36 copy number variation syndrome"	"Orc1 removal from chromatin; Assembly of the pre-replicative complex; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA"	"11"	"0"	"447.2"	"509.4"	"521.2"	"677.5"	"421.3"	"471.7"	"687.9"	"730.5"	"912.9"	"2180.7"	"4893.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15880"	"40S ribosomal protein S2 OS=Homo sapiens OX=9606 GN=RPS2 PE=1 SV=2"	"0.000"	""	"33"	"10"	"22"	"10"	"293"	"31.3"	"10.24"	"4603.69"	"31.66"	"10"	"9"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00333, Pf03719"	"6187"	"ENSG00000140988"	"RPS2"	"B2R5G0; D3DU82; hsa:6187; P15880; Q3MIB1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; RMTs methylate histone arginines; Protein methylation; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"22"	"0"	"745.9"	"802.4"	"892.9"	"1309.6"	"697.0"	"717.7"	"1499.3"	"1655.2"	"2270.1"	"5853.4"	"8072.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00367"	"Glutamate dehydrogenase 1, mitochondrial OS=Homo sapiens OX=9606 GN=GLUD1 PE=1 SV=2"	"0.000"	""	"20"	"9"	"16"	"9"	"558"	"61.4"	"7.80"	"2345.94"	"31.64"	"7"	"9"	"other metabolic processes;other biological processes"	"mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00208, Pf02812"	"2746"	"ENSG00000148672"	"GLUD1"	"B3KV55; B4DGN5; hsa:2746; P00367; Q5TBU3"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Metabolic reprogramming in colon cancer; 22q11.2 copy number variation syndrome; Amino acid metabolism pathway excerpt: histidine catabolism extension; 10q22q23 copy number variation"	"Transcriptional activation of mitochondrial biogenesis; Glutamate and glutamine metabolism"	"8"	"0"	"385.7"	"393.7"	"475.9"	"592.3"	"370.8"	"376.2"	"694.9"	"712.1"	"909.4"	"3300.6"	"6489.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19388"	"DNA-directed RNA polymerases I, II, and III subunit RPABC1 OS=Homo sapiens OX=9606 GN=POLR2E PE=1 SV=4"	"0.000"	""	"40"	"5"	"12"	"5"	"210"	"24.5"	"5.95"	"1948.34"	"31.53"	"3"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01191, Pf03871"	"5434"	"ENSG00000099817"	"POLR2E"	"B2R6L4; D6W5Y1; hsa:5434; O43380; P19388; Q6PIH5; Q9BT06"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"57"	"0"	"320.0"	"302.8"	"406.2"	"553.9"	"331.9"	"323.7"	"752.0"	"845.5"	"1229.3"	"3140.8"	"4372.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SI9"	"Spermatid perinuclear RNA-binding protein OS=Homo sapiens OX=9606 GN=STRBP PE=1 SV=1"	"0.000"	""	"15"	"9"	"17"	"5"	"672"	"73.6"	"8.72"	"3769.86"	"31.44"	"9"	"8"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf00035, Pf07528"	"55342"	"ENSG00000165209"	"STRBP"	"hsa:55342; Q32NB9; Q96SI9; Q9BUE1; Q9BXG4; Q9H0B4; Q9H7V1; Q9NUK4"	""	""	"0"	"0"	"402.2"	"399.0"	"478.0"	"614.6"	"390.3"	"405.3"	"614.8"	"671.4"	"857.0"	"1697.2"	"2466.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12996"	"Cleavage stimulation factor subunit 3 OS=Homo sapiens OX=9606 GN=CSTF3 PE=1 SV=1"	"0.000"	""	"20"	"10"	"19"	"10"	"717"	"82.9"	"8.12"	"4439.47"	"31.42"	"8"	"9"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf05843"	"1479"	"ENSG00000176102"	"CSTF3"	"A8K471; D3DR04; E9PB40; hsa:1479; Q12996; Q32P22; Q96FQ8; Q96QD6; Q96QK4"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"352.3"	"341.9"	"390.2"	"537.0"	"318.0"	"326.8"	"704.5"	"756.6"	"1157.2"	"4065.7"	"6054.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82970"	"High mobility group nucleosome-binding domain-containing protein 5 OS=Homo sapiens OX=9606 GN=HMGN5 PE=1 SV=1"	"0.000"	""	"26"	"5"	"11"	"5"	"282"	"31.5"	"4.55"	"1687.46"	"31.34"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"79366"	"ENSG00000198157"	"HMGN5"	"hsa:79366; P82970; Q5JSL1"	""	""	"0"	"0"	"68.6"	"50.4"	"94.3"	"117.1"	"73.4"	"63.1"	"258.8"	"260.9"	"516.2"	"2437.6"	"2920.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3R9"	"MAGUK p55 subfamily member 5 OS=Homo sapiens OX=9606 GN=MPP5 PE=1 SV=3"	"0.000"	""	"14"	"8"	"19"	"8"	"675"	"77.2"	"6.14"	"4882.38"	"31.11"	"8"	"6"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00595, Pf00625, Pf02828, Pf07653, Pf09060"	"64398"	"ENSG00000072415"	"PALS1"	"A1L380; hsa:64398; Q7Z631; Q86T98; Q8N3R9; Q8N7I5; Q9H9Q0"	"Epithelial to mesenchymal transition in colorectal cancer; Complement system in neuronal development and plasticity"	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction; SARS-CoV-1 targets PDZ proteins in cell-cell junction"	"5"	"0"	"756.6"	"604.6"	"804.1"	"992.3"	"643.6"	"761.8"	"1283.0"	"1342.6"	"1954.3"	"4960.3"	"6871.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55010"	"Eukaryotic translation initiation factor 5 OS=Homo sapiens OX=9606 GN=EIF5 PE=1 SV=2"	"0.000"	""	"13"	"7"	"12"	"7"	"431"	"49.2"	"5.58"	"1343.33"	"30.97"	"2"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01873, Pf02020"	"1983"	"ENSG00000100664"	"EIF5"	"hsa:1983; P55010; Q53XB3; Q9H5N2; Q9UG48"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"4"	"0"	"215.5"	"210.8"	"278.4"	"334.1"	"202.3"	"211.2"	"561.7"	"641.9"	"794.0"	"5216.8"	"13706.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84103"	"Serine/arginine-rich splicing factor 3 OS=Homo sapiens OX=9606 GN=SRSF3 PE=1 SV=1"	"0.000"	""	"41"	"7"	"14"	"7"	"164"	"19.3"	"11.65"	"1678.45"	"30.92"	"4"	"7"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6428"	"ENSG00000112081"	"SRSF3"	"B4E241; hsa:6428; O08831; P23152; P84103; Q5R3K0"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"1245.4"	"1287.6"	"1139.2"	"1549.9"	"1016.7"	"834.5"	"1623.8"	"1731.9"	"1864.1"	"3504.4"	"4641.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13263"	"Transcription intermediary factor 1-beta OS=Homo sapiens OX=9606 GN=TRIM28 PE=1 SV=5"	"0.000"	""	"9"	"6"	"15"	"6"	"835"	"88.5"	"5.77"	"3787.78"	"30.89"	"6"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00628, Pf00643, Pf14634"	"10155"	"ENSG00000130726"	"TRIM28"	"hsa:10155; O00677; Q13263; Q7Z632; Q93040; Q96IM1"	"Corticotropin-releasing hormone signaling pathway; Mesodermal commitment pathway; ATM signaling in development and disease"	"HCMV Early Events; SUMOylation of transcription cofactors; Generic Transcription Pathway"	"6"	"0"	"317.6"	"303.0"	"409.7"	"466.3"	"295.7"	"325.9"	"529.5"	"519.5"	"697.8"	"1998.9"	"4187.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTI5"	"Sister chromatid cohesion protein PDS5 homolog B OS=Homo sapiens OX=9606 GN=PDS5B PE=1 SV=1"	"0.000"	""	"7"	"8"	"15"	"5"	"1447"	"164.6"	"8.47"	"2006.75"	"30.88"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf20168"	"23047"	"ENSG00000083642"	"PDS5B"	"hsa:23047; Q5R3S3; Q5W0K8; Q6NSC3; Q8IXT6; Q9H5N8; Q9NTI5; Q9Y2I5; Q9Y451"	"Cohesin complex - Cornelia de Lange syndrome; 10q22q23 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"6"	"0"	"194.5"	"181.3"	"198.3"	"249.9"	"199.0"	"190.6"	"304.0"	"302.8"	"448.2"	"826.4"	"962.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13112"	"Chromatin assembly factor 1 subunit B OS=Homo sapiens OX=9606 GN=CHAF1B PE=1 SV=1"	"0.000"	""	"16"	"9"	"17"	"9"	"559"	"61.5"	"7.50"	"2707.44"	"30.72"	"8"	"9"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf15512"	"8208"	"ENSG00000159259"	"CHAF1B"	"hsa:8208; Q13112; Q99548"	""	""	"0"	"0"	"971.1"	"851.7"	"1077.4"	"1195.8"	"925.0"	"941.6"	"1609.4"	"1667.1"	"2496.1"	"4530.0"	"4936.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04837"	"Single-stranded DNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SSBP1 PE=1 SV=1"	"0.000"	""	"45"	"6"	"12"	"6"	"148"	"17.2"	"9.60"	"1846.31"	"30.69"	"4"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00436"	"6742"	"ENSG00000106028; ENSG00000262771"	"SSBP1"	"hsa:6742; Q04837"	""	"Transcriptional activation of mitochondrial biogenesis"	"1"	"0"	"489.0"	"510.9"	"477.2"	"654.2"	"456.4"	"490.4"	"715.1"	"749.1"	"877.3"	"1955.7"	"2668.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4Z0"	"U6 snRNA-associated Sm-like protein LSm4 OS=Homo sapiens OX=9606 GN=LSM4 PE=1 SV=1"	"0.000"	""	"28"	"6"	"18"	"6"	"139"	"15.3"	"9.99"	"3438.21"	"30.69"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"25804"	"ENSG00000130520"	"LSM4"	"hsa:25804; Q9Y4Z0"	"Ciliary landscape"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"443.9"	"394.5"	"522.5"	"653.9"	"426.9"	"461.6"	"684.7"	"700.6"	"775.2"	"1665.3"	"3177.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15144"	"Actin-related protein 2/3 complex subunit 2 OS=Homo sapiens OX=9606 GN=ARPC2 PE=1 SV=1"	"0.000"	""	"34"	"8"	"16"	"8"	"300"	"34.3"	"7.36"	"2378.88"	"30.64"	"6"	"6"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf04045"	"10109"	"ENSG00000163466"	"ARPC2"	"hsa:10109; O15144; Q92801; Q9P1D4"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"346.8"	"280.3"	"391.7"	"422.0"	"322.2"	"345.8"	"844.9"	"905.2"	"1681.7"	"5579.1"	"6950.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14978"	"Nucleolar and coiled-body phosphoprotein 1 OS=Homo sapiens OX=9606 GN=NOLC1 PE=1 SV=2"	"0.000"	""	"12"	"8"	"17"	"8"	"699"	"73.6"	"9.47"	"3281.03"	"30.57"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05022"	"9221"	"ENSG00000166197"	"NOLC1"	"hsa:9221; Q14978; Q15030; Q5VV70; Q9BUV3"	""	""	"0"	"0"	"607.7"	"528.6"	"580.1"	"652.0"	"550.8"	"564.8"	"831.2"	"866.6"	"1040.1"	"1768.9"	"2373.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23588"	"Eukaryotic translation initiation factor 4B OS=Homo sapiens OX=9606 GN=EIF4B PE=1 SV=2"	"0.000"	""	"14"	"7"	"14"	"7"	"611"	"69.1"	"5.73"	"2109.91"	"30.39"	"5"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf00076"	"1975"	"ENSG00000063046"	"EIF4B"	"B4DS13; hsa:1975; P23588; Q4G0E3; Q53HQ2; Q6GPH5; Q6IB46; Q8WYK5"	"Translation factors; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Pleural mesothelioma; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; mTORC1-mediated signalling"	"14"	"0"	"307.7"	"254.5"	"336.8"	"393.7"	"299.3"	"318.3"	"717.8"	"769.0"	"1232.3"	"4858.3"	"6475.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62081"	"40S ribosomal protein S7 OS=Homo sapiens OX=9606 GN=RPS7 PE=1 SV=1"	"0.000"	""	"32"	"6"	"11"	"6"	"194"	"22.1"	"10.10"	"1473.56"	"30.39"	"3"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01251"	"6201"	"ENSG00000171863"	"RPS7"	"hsa:6201; P23821; P24818; P62081; Q57Z92; Q6IPH1"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; rRNA modification in the nucleus and cytosol"	"20"	"0"	"260.7"	"273.7"	"339.4"	"469.6"	"269.0"	"292.2"	"631.3"	"645.4"	"1078.7"	"3520.1"	"3246.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95232"	"Luc7-like protein 3 OS=Homo sapiens OX=9606 GN=LUC7L3 PE=1 SV=2"	"0.000"	""	"19"	"9"	"19"	"9"	"432"	"51.4"	"9.79"	"2888.50"	"30.37"	"8"	"9"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf03194"	"51747"	"ENSG00000108848"	"LUC7L3"	"B3KN54; D3DTY1; hsa:51747; O95232; Q6PHR9; Q9NUY0; Q9P2S7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"583.4"	"517.2"	"616.4"	"913.9"	"498.4"	"532.1"	"1011.8"	"982.3"	"1474.3"	"5230.4"	"7984.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30040"	"Endoplasmic reticulum resident protein 29 OS=Homo sapiens OX=9606 GN=ERP29 PE=1 SV=4"	"0.000"	""	"33"	"8"	"15"	"8"	"261"	"29.0"	"7.31"	"2492.04"	"30.35"	"6"	"7"	"protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf07749, Pf07912"	"10961"	"ENSG00000089248"	"ERP29"	"C9J183; hsa:10961; P30040; Q3MJC3; Q6FHT4"	""	""	"0"	"0"	"111.8"	"103.9"	"136.8"	"180.3"	"108.6"	"120.2"	"416.5"	"458.6"	"917.9"	"5019.0"	"6950.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYL9"	"Tropomodulin-3 OS=Homo sapiens OX=9606 GN=TMOD3 PE=1 SV=1"	"0.000"	""	"22"	"6"	"12"	"6"	"352"	"39.6"	"5.19"	"3442.61"	"30.29"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"29766"	"ENSG00000138594"	"TMOD3"	"B2R6G7; hsa:29766; Q9NT43; Q9NYL9; Q9NZR0"	"VEGFA-VEGFR2 signaling"	"Striated Muscle Contraction; RND3 GTPase cycle; RHOBTB2 GTPase cycle"	"4"	"0"	"449.0"	"377.4"	"462.2"	"554.5"	"369.5"	"401.5"	"551.2"	"558.6"	"731.0"	"1391.3"	"2049.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35612"	"Beta-adducin OS=Homo sapiens OX=9606 GN=ADD2 PE=1 SV=3"	"0.000"	""	"19"	"10"	"16"	"8"	"726"	"80.8"	"5.92"	"2534.25"	"30.23"	"7"	"8"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00596"	"119"	"ENSG00000075340"	"ADD2"	"A8K4P2; B4DM17; D6W5G7; D6W5G8; hsa:119; P35612; Q13482; Q16412; Q59G82; Q5U5P4; Q6P0P2; Q6PGQ4; Q7Z688; Q7Z689; Q7Z690; Q7Z691"	""	"Miscellaneous transport and binding events"	"1"	"0"	"196.0"	"152.3"	"203.6"	"220.7"	"173.7"	"198.8"	"370.1"	"413.1"	"764.4"	"1458.5"	"1751.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1G4"	"Leucine-rich repeat-containing protein 47 OS=Homo sapiens OX=9606 GN=LRRC47 PE=1 SV=1"	"0.000"	""	"17"	"8"	"15"	"8"	"583"	"63.4"	"8.28"	"2894.47"	"30.20"	"7"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00560, Pf03483, Pf12799"	"57470"	"ENSG00000130764"	"LRRC47"	"hsa:57470; Q8N1G4; Q9ULN5"	""	""	"0"	"0"	"499.2"	"454.0"	"561.7"	"673.4"	"460.9"	"492.9"	"1092.7"	"1160.5"	"1830.5"	"2872.7"	"2684.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13620"	"Cullin-4B OS=Homo sapiens OX=9606 GN=CUL4B PE=1 SV=4"	"0.000"	""	"10"	"8"	"14"	"5"	"913"	"103.9"	"7.37"	"2320.48"	"29.98"	"6"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8450"	"ENSG00000158290"	"CUL4B"	"B1APK5; B3KVX4; B7Z5K8; hsa:8450; Q13620; Q6PIE4; Q6UP07; Q7Z673; Q9BY37; Q9UEB7; Q9UED7"	"Mesodermal commitment pathway; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"13"	"3"	"164.3"	"138.5"	"215.7"	"258.0"	"171.9"	"158.6"	"398.9"	"449.1"	"800.6"	"3195.2"	"4664.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T58"	"Msx2-interacting protein OS=Homo sapiens OX=9606 GN=SPEN PE=1 SV=1"	"0.000"	""	"3"	"8"	"16"	"8"	"3664"	"402.0"	"7.64"	"3341.86"	"29.95"	"8"	"8"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf07744"	"23013"	"ENSG00000065526"	"SPEN"	"hsa:23013; Q96T58; Q9H9A8; Q9NWH5; Q9UQ01; Q9Y556"	"Notch signaling pathway"	"RHOBTB1 GTPase cycle"	"2"	"0"	"943.9"	"815.2"	"1076.3"	"1139.3"	"922.3"	"897.0"	"1219.4"	"1214.5"	"1458.2"	"1962.8"	"2408.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0J8"	"pre-mRNA 3' end processing protein WDR33 OS=Homo sapiens OX=9606 GN=WDR33 PE=1 SV=2"	"0.000"	""	"5"	"4"	"11"	"4"	"1336"	"145.8"	"9.17"	"2532.29"	"29.86"	"3"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"55339"	"ENSG00000136709"	"WDR33"	"hsa:55339; Q05DP8; Q53FG9; Q587J1; Q69YF7; Q6NUQ0; Q9C0J8; Q9NUL1"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"441.6"	"451.7"	"501.0"	"551.2"	"432.5"	"434.1"	"549.8"	"594.5"	"657.5"	"1338.2"	"1890.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14571"	"Inositol 1,4,5-trisphosphate receptor type 2 OS=Homo sapiens OX=9606 GN=ITPR2 PE=1 SV=2"	"0.000"	""	"6"	"12"	"18"	"11"	"2701"	"307.9"	"6.43"	"3343.59"	"29.76"	"10"	"8"	"stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3709"	"ENSG00000123104"	"ITPR2"	"hsa:3709; O94773; Q14571"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ion homeostasis; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"21"	"1"	"496.8"	"482.0"	"611.3"	"621.2"	"467.7"	"488.9"	"749.8"	"733.8"	"950.5"	"2258.0"	"3565.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55735"	"Protein SEC13 homolog OS=Homo sapiens OX=9606 GN=SEC13 PE=1 SV=3"	"0.000"	""	"26"	"6"	"14"	"6"	"322"	"35.5"	"5.48"	"3102.56"	"29.62"	"6"	"6"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00400"	"6396"	"ENSG00000157020"	"SEC13"	"A8MV37; B4DXJ1; hsa:6396; P55735; Q5BJF0; Q9BRM6; Q9BUG7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; Separation of Sister Chromatids; HCMV Late Events; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Amino acids regulate mTORC1; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPII-mediated vesicle transport; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Postmitotic nuclear pore complex (NPC) reformation"	"40"	"0"	"819.6"	"548.1"	"952.4"	"1352.2"	"792.6"	"798.9"	"1553.7"	"1592.1"	"2124.6"	"3610.8"	"4739.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX58"	"Cell growth-regulating nucleolar protein OS=Homo sapiens OX=9606 GN=LYAR PE=1 SV=2"	"0.000"	""	"27"	"8"	"13"	"8"	"379"	"43.6"	"9.54"	"2244.65"	"29.61"	"5"	"8"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"390.8"	"383.4"	"541.4"	"576.7"	"459.8"	"410.3"	"705.4"	"723.6"	"999.5"	"1809.5"	"2120.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11171"	"Protein 4.1 OS=Homo sapiens OX=9606 GN=EPB41 PE=1 SV=4"	"0.000"	""	"13"	"8"	"15"	"7"	"864"	"97.0"	"5.58"	"2364.19"	"29.35"	"7"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2035"	"ENSG00000159023"	"EPB41"	"B1ALH8; B1ALH9; D3DPM9; D3DPN0; hsa:2035; P11171; P11176; Q14245; Q5TB35; Q5VXN8; Q8IXV9; Q9Y578; Q9Y579"	"VEGFA-VEGFR2 signaling; Splicing factor NOVA regulated synaptic proteins; IL-18 signaling pathway"	"Neurexins and neuroligins"	"4"	"0"	"614.8"	"466.7"	"625.6"	"722.5"	"552.7"	"586.5"	"1155.5"	"1233.7"	"1639.7"	"1263.8"	"1399.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62937"	"Peptidyl-prolyl cis-trans isomerase A OS=Homo sapiens OX=9606 GN=PPIA PE=1 SV=2"	"0.000"	""	"38"	"8"	"16"	"8"	"165"	"18.0"	"7.81"	"3251.95"	"29.33"	"7"	"7"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00160"	"5478"	"ENSG00000196262"	"PPIA"	"A8K220; hsa:5478; P05092; P62937; Q3KQW3; Q567Q0; Q6IBU5; Q96IX3; Q9BRU4; Q9BTY9; Q9UC61"	"Prolactin signaling pathway"	"Neutrophil degranulation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Budding and maturation of HIV virion; Platelet degranulation ; Basigin interactions; SARS-CoV-1 activates/modulates innate immune responses; Integration of provirus; APOBEC3G mediated resistance to HIV-1 infection; Calcineurin activates NFAT; Binding and entry of HIV virion; Assembly Of The HIV Virion; Uncoating of the HIV Virion; Minus-strand DNA synthesis; Plus-strand DNA synthesis"	"16"	"0"	"407.3"	"413.4"	"614.6"	"1306.8"	"349.9"	"332.5"	"702.3"	"731.9"	"862.5"	"2273.5"	"6580.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y265"	"RuvB-like 1 OS=Homo sapiens OX=9606 GN=RUVBL1 PE=1 SV=1"	"0.000"	""	"20"	"7"	"15"	"7"	"456"	"50.2"	"6.42"	"2579.85"	"29.28"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06068, Pf17856"	"8607"	"ENSG00000175792; ENSG00000284901"	"RUVBL1"	"B2R5S0; hsa:8607; P82276; Q1KMR0; Q53HK5; Q53HL7; Q53Y27; Q9BSX9; Q9Y265"	"Gastric cancer network 1; lncRNA in canonical Wnt signaling and colorectal cancer"	"Ub-specific processing proteases; UCH proteinases; Deposition of new CENPA-containing nucleosomes at the centromere; Formation of the beta-catenin:TCF transactivating complex; Telomere Extension By Telomerase; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"9"	"0"	"309.4"	"274.9"	"343.5"	"474.1"	"289.2"	"287.0"	"547.1"	"603.9"	"810.4"	"2088.6"	"2978.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96I25"	"Splicing factor 45 OS=Homo sapiens OX=9606 GN=RBM17 PE=1 SV=1"	"0.000"	""	"19"	"8"	"18"	"7"	"401"	"44.9"	"5.97"	"3173.55"	"29.19"	"8"	"8"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf01585"	"84991"	"ENSG00000134453"	"RBM17"	"hsa:84991; Q96GY6; Q96I25"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"1"	"331.4"	"304.3"	"384.6"	"468.0"	"333.5"	"331.3"	"533.5"	"552.5"	"698.8"	"2404.9"	"4703.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15424"	"Scaffold attachment factor B1 OS=Homo sapiens OX=9606 GN=SAFB PE=1 SV=4"	"0.000"	""	"10"	"9"	"19"	"5"	"915"	"102.6"	"5.47"	"3545.78"	"29.10"	"8"	"7"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"6294"	"ENSG00000160633"	"SAFB"	"A0AV56; B7Z5B6; B7ZLP6; F5H0H3; hsa:6294; O60406; Q15424; Q59HH8"	"Interleukin-1 (IL-1) structural pathway"	"SUMOylation of transcription cofactors"	"2"	"4"	"1567.1"	"1408.7"	"1716.3"	"2240.1"	"1361.8"	"1382.0"	"1918.7"	"1943.0"	"2000.1"	"4177.5"	"8269.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35658"	"Nuclear pore complex protein Nup214 OS=Homo sapiens OX=9606 GN=NUP214 PE=1 SV=2"	"0.000"	""	"4"	"6"	"12"	"6"	"2090"	"213.5"	"7.47"	"1627.83"	"29.08"	"4"	"6"	"cell cycle OR cell proliferation;other metabolic processes;transport;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf18617"	"8021"	"ENSG00000126883"	"NUP214"	"A6NFQ0; hsa:8021; P35658; Q15010; Q3KQZ0; Q5JUP7; Q75R47; Q86XD3"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HuR (ELAVL1) binds and stabilizes mRNA"	"29"	"0"	"579.8"	"452.2"	"626.6"	"645.0"	"501.2"	"578.5"	"801.7"	"802.1"	"945.4"	"2074.4"	"3086.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18583"	"Protein SON OS=Homo sapiens OX=9606 GN=SON PE=1 SV=4"	"0.000"	""	"4"	"9"	"21"	"9"	"2426"	"263.7"	"5.64"	"3946.50"	"29.06"	"9"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf14709, Pf17069"	"6651"	"ENSG00000159140"	"SON"	"D3DSF5; D3DSF6; E7ETE8; E7EU67; E7EVW3; E9PFQ2; hsa:6651; O14487; O95981; P18583; Q14120; Q6PKE0; Q9H7B1; Q9P070; Q9P072; Q9UKP9; Q9UPY0"	""	""	"0"	"0"	"927.6"	"871.7"	"1103.0"	"1366.0"	"912.4"	"935.1"	"1320.5"	"1341.1"	"1545.2"	"3677.7"	"6212.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76021"	"Ribosomal L1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RSL1D1 PE=1 SV=3"	"0.000"	""	"22"	"8"	"16"	"8"	"490"	"54.9"	"10.13"	"3429.06"	"29.05"	"8"	"8"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00687"	"26156"	"ENSG00000171490"	"RSL1D1"	"B4DJ58; D3DUG7; hsa:26156; O76021; Q2M1T7; Q6PL22; Q8IWS7; Q8WUZ1; Q9HDA9; Q9Y3Z9"	""	""	"0"	"0"	"704.1"	"571.8"	"737.2"	"867.4"	"705.2"	"679.8"	"896.1"	"930.7"	"1156.9"	"1909.8"	"2783.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15371"	"Eukaryotic translation initiation factor 3 subunit D OS=Homo sapiens OX=9606 GN=EIF3D PE=1 SV=1"	"0.000"	""	"20"	"7"	"11"	"7"	"548"	"63.9"	"6.05"	"1651.54"	"29.03"	"4"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf05091"	"8664"	"ENSG00000100353"	"EIF3D"	"A8MWD3; B2R7D4; B4DTF8; B4DVY1; hsa:8664; O15371; Q3MJD9; Q5M9Q6"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"302.8"	"261.5"	"345.0"	"435.9"	"295.0"	"303.3"	"460.7"	"484.8"	"577.1"	"1206.9"	"2828.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NC51"	"Plasminogen activator inhibitor 1 RNA-binding protein OS=Homo sapiens OX=9606 GN=SERBP1 PE=1 SV=2"	"0.000"	""	"25"	"9"	"16"	"9"	"408"	"44.9"	"8.65"	"3887.29"	"29.02"	"9"	"7"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf04774, Pf16174"	"26135"	"ENSG00000142864"	"SERBP1"	"hsa:26135; Q5VU19; Q5VU20; Q5VU22; Q8NC51; Q8WUH0; Q96SE2; Q9BTY3; Q9BUM4; Q9Y367; Q9Y4S3"	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"1"	"0"	"1091.5"	"849.1"	"1212.9"	"1230.2"	"1066.8"	"1095.3"	"1401.5"	"1411.2"	"1610.6"	"2558.5"	"4374.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92747"	"Actin-related protein 2/3 complex subunit 1A OS=Homo sapiens OX=9606 GN=ARPC1A PE=2 SV=2"	"0.000"	""	"26"	"8"	"14"	"7"	"370"	"41.5"	"8.18"	"2301.54"	"29.01"	"6"	"8"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"10552"	"ENSG00000241685"	"ARPC1A"	"A4D276; B4DLQ7; D6W5S1; hsa:10552; Q7Z5U8; Q86WU5; Q8IXQ0; Q92747"	"Pathogenic Escherichia coli infection"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"1"	"298.9"	"280.3"	"312.7"	"403.5"	"305.9"	"306.4"	"898.0"	"1005.7"	"2075.3"	"5283.6"	"6137.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62314"	"Small nuclear ribonucleoprotein Sm D1 OS=Homo sapiens OX=9606 GN=SNRPD1 PE=1 SV=1"	"0.000"	""	"37"	"3"	"14"	"3"	"119"	"13.3"	"11.56"	"3008.10"	"29.00"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01423"	"6632"	"ENSG00000167088"	"SNRPD1"	"B5BTZ1; hsa:6632; P13641; P62314"	"mRNA processing"	"mRNA Splicing - Major Pathway; SARS-CoV-2 modulates host translation machinery; snRNP Assembly; mRNA Splicing - Minor Pathway"	"5"	"0"	"233.0"	"323.7"	"261.5"	"322.2"	"233.8"	"248.7"	"333.3"	"377.9"	"433.2"	"1157.8"	"1444.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05198"	"Eukaryotic translation initiation factor 2 subunit 1 OS=Homo sapiens OX=9606 GN=EIF2S1 PE=1 SV=3"	"0.000"	""	"24"	"7"	"16"	"7"	"315"	"36.1"	"5.08"	"2508.27"	"28.99"	"5"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00575, Pf07541"	"1965"	"ENSG00000134001"	"EIF2S1"	"hsa:1965; P05198"	"Translation factors; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; Ebola virus infection in host; Nonalcoholic fatty liver disease; Measles virus infection; Unfolded protein response; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell; Alzheimer's disease"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; ABC-family proteins mediated transport; Response of EIF2AK1 (HRI) to heme deficiency; PERK regulates gene expression; Recycling of eIF2:GDP; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"19"	"0"	"609.5"	"652.9"	"618.6"	"878.0"	"620.2"	"639.0"	"1714.7"	"2099.5"	"3597.7"	"5393.2"	"4775.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62826"	"GTP-binding nuclear protein Ran OS=Homo sapiens OX=9606 GN=RAN PE=1 SV=3"	"0.000"	""	"25"	"6"	"11"	"6"	"216"	"24.4"	"7.49"	"1582.41"	"28.96"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00071"	"5901"	"ENSG00000132341"	"RAN"	"A8K3Z8; hsa:5901; P17080; P28746; P28747; P62826; Q6IPB2; Q86V08; Q8NI90; Q9CSP3; Q9CWI7; Q9CZA2; Q9UDJ5; Q9UEU9"	"Androgen receptor signaling pathway; miRNA biogenesis; 22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Nuclear import of Rev protein; Transcriptional regulation by small RNAs; tRNA processing in the nucleus; Regulation of cholesterol biosynthesis by SREBP (SREBF); MicroRNA (miRNA) biogenesis; Postmitotic nuclear pore complex (NPC) reformation"	"11"	"0"	"606.8"	"612.8"	"659.1"	"898.6"	"580.5"	"581.7"	"986.7"	"1023.2"	"1279.6"	"2305.6"	"2932.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13995"	"Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD2 PE=1 SV=2"	"0.000"	""	"26"	"7"	"10"	"7"	"350"	"37.9"	"8.73"	"1332.73"	"28.92"	"4"	"6"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00763, Pf02882"	"10797"	"ENSG00000065911"	"MTHFD2"	"hsa:10797; P13995; Q53G90; Q53GV5; Q53S36; Q7Z650"	"Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"4"	"0"	"366.4"	"345.1"	"427.6"	"544.3"	"325.2"	"363.1"	"645.5"	"695.5"	"894.5"	"2331.3"	"3848.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94832"	"Unconventional myosin-Id OS=Homo sapiens OX=9606 GN=MYO1D PE=1 SV=2"	"0.000"	""	"7"	"7"	"16"	"7"	"1006"	"116.1"	"9.39"	"3083.07"	"28.80"	"7"	"7"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf06017"	"4642"	"ENSG00000176658"	"MYO1D"	"A6H8V3; hsa:4642; O94832; Q8NHP9"	""	""	"0"	"0"	"306.9"	"309.7"	"351.5"	"493.8"	"294.1"	"290.0"	"714.0"	"793.9"	"1125.7"	"2838.4"	"4025.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBL3"	"Set1/Ash2 histone methyltransferase complex subunit ASH2 OS=Homo sapiens OX=9606 GN=ASH2L PE=1 SV=1"	"0.000"	""	"14"	"7"	"12"	"7"	"628"	"68.7"	"5.69"	"1976.99"	"28.79"	"5"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622"	"9070"	"ENSG00000129691"	"ASH2L"	"A8K7C3; D3DSW9; hsa:9070; O60659; O60660; Q96B62; Q9UBL3"	"Kleefstra syndrome"	"Deactivation of the beta-catenin transactivating complex; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"7"	"0"	"297.8"	"274.8"	"319.1"	"364.8"	"321.2"	"302.5"	"615.5"	"628.1"	"1005.3"	"3482.9"	"5248.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRZ9"	"Lymphoid-specific helicase OS=Homo sapiens OX=9606 GN=HELLS PE=1 SV=1"	"0.000"	""	"8"	"5"	"10"	"5"	"838"	"97.0"	"7.93"	"1792.18"	"28.78"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"3070"	"ENSG00000119969"	"HELLS"	"B2RB41; hsa:3070; Q3LID1; Q6I7N7; Q76H76; Q76H77; Q76H78; Q76H79; Q76H80; Q76H81; Q7Z397; Q7Z5X2; Q8N6P4; Q9H4P5; Q9NRZ9"	"Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"431.3"	"439.7"	"550.7"	"650.2"	"424.8"	"456.9"	"708.4"	"729.6"	"942.8"	"1457.9"	"1622.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18124"	"60S ribosomal protein L7 OS=Homo sapiens OX=9606 GN=RPL7 PE=1 SV=1"	"0.000"	""	"29"	"6"	"15"	"6"	"248"	"29.2"	"10.65"	"2618.49"	"28.66"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00327, Pf08079"	"6129"	"ENSG00000147604"	"RPL7"	"A8K504; hsa:6129; P18124; Q15289; Q3KQU0; Q5I0X1; Q6IBM9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"354.5"	"320.9"	"472.4"	"612.4"	"392.9"	"390.7"	"699.4"	"698.8"	"890.5"	"2094.2"	"3233.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51610"	"Host cell factor 1 OS=Homo sapiens OX=9606 GN=HCFC1 PE=1 SV=2"	"0.000"	""	"5"	"9"	"16"	"9"	"2035"	"208.6"	"7.46"	"3226.14"	"28.60"	"8"	"8"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01344, Pf13415"	"3054"	"ENSG00000172534"	"HCFC1"	"hsa:3054; P51610; Q6P4G5"	"Mitochondrial gene expression; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Transcriptional activation of mitochondrial biogenesis; HATs acetylate histones"	"6"	"0"	"601.4"	"590.0"	"655.5"	"829.5"	"552.6"	"576.5"	"898.5"	"910.9"	"1124.8"	"2729.0"	"4319.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YN2"	"CWF19-like protein 1 OS=Homo sapiens OX=9606 GN=CWF19L1 PE=1 SV=2"	"0.000"	""	"15"	"6"	"15"	"6"	"538"	"60.6"	"7.24"	"3513.05"	"28.59"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"enzyme regulator activity"	"Pf04676, Pf04677"	"55280"	"ENSG00000095485"	"CWF19L1"	"B4DHX1; D3DR66; hsa:55280; Q5W0I3; Q69YN2; Q96HC3; Q9H865; Q9NV13"	""	""	"0"	"0"	"194.9"	"171.4"	"230.6"	"282.2"	"207.4"	"211.3"	"449.7"	"483.3"	"774.7"	"1659.1"	"2072.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L7X3"	"Serine/threonine-protein kinase TAO1 OS=Homo sapiens OX=9606 GN=TAOK1 PE=1 SV=1"	"0.000"	""	"7"	"6"	"14"	"6"	"1001"	"116.0"	"7.65"	"3536.19"	"28.47"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"57551"	"ENSG00000160551"	"TAOK1"	"A2RUT8; B7ZLV6; hsa:57551; Q7L7X3; Q96L75; Q9H2K7; Q9H7S5; Q9P2I6"	"Microtubule cytoskeleton regulation; MAPK signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"0"	"272.0"	"219.5"	"337.9"	"347.0"	"255.7"	"324.3"	"591.7"	"608.9"	"702.3"	"1159.2"	"1415.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P258"	"Protein RCC2 OS=Homo sapiens OX=9606 GN=RCC2 PE=1 SV=2"	"0.000"	""	"18"	"8"	"16"	"8"	"522"	"56.0"	"8.78"	"3277.92"	"28.45"	"8"	"6"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00415"	"55920"	"ENSG00000179051; ENSG00000281540"	"RCC2"	"hsa:55920; Q8IVL9; Q9BSN6; Q9NPV8; Q9P258"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"487.9"	"518.1"	"503.0"	"591.6"	"479.3"	"485.9"	"835.3"	"859.9"	"1262.1"	"3439.8"	"3923.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60264"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5 OS=Homo sapiens OX=9606 GN=SMARCA5 PE=1 SV=1"	"0.000"	""	"11"	"10"	"17"	"5"	"1052"	"121.8"	"8.09"	"3342.82"	"28.41"	"9"	"8"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf09110, Pf09111"	"8467"	"ENSG00000153147"	"SMARCA5"	"hsa:8467; O60264"	"10q11.21q11.23 copy number variation syndrome"	"Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; NoRC negatively regulates rRNA expression"	"5"	"0"	"239.5"	"230.4"	"279.1"	"324.6"	"246.2"	"251.3"	"370.1"	"409.4"	"497.2"	"959.4"	"1226.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZI8"	"Insulin-like growth factor 2 mRNA-binding protein 1 OS=Homo sapiens OX=9606 GN=IGF2BP1 PE=1 SV=2"	"0.000"	""	"11"	"5"	"12"	"4"	"577"	"63.4"	"9.20"	"2544.72"	"28.32"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10642"	"ENSG00000159217"	"IGF2BP1"	"C9JT33; hsa:10642; Q9NZI8"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; eIF5A regulation in response to inhibition of the nuclear export system"	"MAPK6/MAPK4 signaling; Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"4"	"0"	"284.2"	"288.8"	"282.4"	"378.9"	"287.4"	"275.4"	"414.1"	"452.1"	"538.2"	"1039.2"	"1503.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43684"	"Mitotic checkpoint protein BUB3 OS=Homo sapiens OX=9606 GN=BUB3 PE=1 SV=1"	"0.000"	""	"27"	"8"	"18"	"8"	"328"	"37.1"	"6.84"	"3295.55"	"28.31"	"8"	"8"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"9184"	"ENSG00000154473"	"BUB3"	"A6NJ42; B2R6E7; D3DRE9; hsa:9184; O43684; O43685"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"12"	"0"	"997.1"	"920.8"	"997.2"	"1269.5"	"846.2"	"829.1"	"1510.5"	"1559.0"	"1996.5"	"4793.3"	"5774.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22033"	"Methylmalonyl-CoA mutase, mitochondrial OS=Homo sapiens OX=9606 GN=MMUT PE=1 SV=4"	"0.000"	""	"12"	"7"	"14"	"7"	"750"	"83.1"	"6.93"	"1957.37"	"28.30"	"5"	"7"	"other metabolic processes;developmental processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01642, Pf02310"	"4594"	"ENSG00000146085"	"MMUT"	"A8K953; hsa:4594; P22033; Q5SYZ3; Q96B11; Q9UD64"	"Vitamin B12 metabolism; Amino acid metabolism"	"Propionyl-CoA catabolism; Defective MMAA causes MMA, cblA type; Defective MUT causes MMAM; Cobalamin (Cbl) metabolism"	"6"	"0"	"199.6"	"184.1"	"258.6"	"309.0"	"197.9"	"245.9"	"787.9"	"885.1"	"1262.4"	"3073.6"	"4763.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60832"	"H/ACA ribonucleoprotein complex subunit DKC1 OS=Homo sapiens OX=9606 GN=DKC1 PE=1 SV=3"	"0.000"	""	"12"	"6"	"12"	"6"	"514"	"57.6"	"9.42"	"2725.54"	"28.26"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01472, Pf01509, Pf08068, Pf16198"	"1736"	"ENSG00000130826"	"DKC1"	"F5BSB3; hsa:1736; O43845; O60832; Q96G67; Q9Y505"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"374.8"	"381.7"	"411.8"	"492.4"	"332.1"	"353.0"	"589.2"	"598.9"	"825.0"	"2211.6"	"2607.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08708"	"40S ribosomal protein S17 OS=Homo sapiens OX=9606 GN=RPS17 PE=1 SV=2"	"0.000"	""	"56"	"6"	"9"	"6"	"135"	"15.5"	"9.85"	"1118.29"	"28.25"	"3"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00833"	"6218"	"ENSG00000182774; ENSG00000278229"	"RPS17"	"B2R4U4; hsa:6218; P08708; P0CW22"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"298.5"	"336.3"	"355.4"	"485.4"	"334.1"	"306.8"	"464.8"	"486.6"	"614.1"	"1279.9"	"1280.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47813"	"Eukaryotic translation initiation factor 1A, X-chromosomal OS=Homo sapiens OX=9606 GN=EIF1AX PE=1 SV=2"	"0.000"	""	"58"	"8"	"15"	"8"	"144"	"16.5"	"5.24"	"3388.03"	"28.24"	"7"	"6"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"1964"	"ENSG00000173674"	"EIF1AX"	"B2R5U5; hsa:1964; P47813; Q0VGC2; Q5JPS5; Q5JPS6"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"8"	"0"	"246.8"	"212.0"	"300.9"	"371.0"	"263.3"	"245.2"	"1223.9"	"1391.5"	"2877.4"	"11593.8"	"5674.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15143"	"Actin-related protein 2/3 complex subunit 1B OS=Homo sapiens OX=9606 GN=ARPC1B PE=1 SV=3"	"0.000"	""	"22"	"7"	"13"	"6"	"372"	"40.9"	"8.35"	"1996.57"	"28.22"	"4"	"7"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400"	"10095"	"ENSG00000130429"	"ARPC1B"	"hsa:10095; O15143; Q9BU00"	"Pathogenic Escherichia coli infection; Microglia pathogen phagocytosis pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; EPHB-mediated forward signaling"	"6"	"0"	"488.8"	"572.9"	"524.1"	"643.8"	"479.2"	"451.4"	"985.5"	"1057.8"	"1931.6"	"5102.1"	"7629.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55036"	"26S proteasome non-ATPase regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMD4 PE=1 SV=1"	"0.000"	""	"23"	"6"	"13"	"6"	"377"	"40.7"	"4.79"	"2738.79"	"28.21"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02809, Pf13519"	"5710"	"ENSG00000159352"	"PSMD4"	"D3DV16; hsa:5710; P55036; Q5VWC5; Q9NS92"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling; Alzheimer's disease"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Antigen processing: Ubiquitination & Proteasome degradation; Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of RUNX2 expression and activity; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"354.2"	"261.7"	"370.5"	"417.0"	"313.2"	"330.2"	"671.8"	"676.8"	"985.8"	"3951.9"	"5358.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z6E9"	"E3 ubiquitin-protein ligase RBBP6 OS=Homo sapiens OX=9606 GN=RBBP6 PE=1 SV=1"	"0.000"	""	"5"	"7"	"14"	"7"	"1792"	"201.4"	"9.64"	"3051.95"	"28.17"	"7"	"7"	"protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04564, Pf08783, Pf13696"	"5930"	"ENSG00000122257"	"RBBP6"	"hsa:5930; Q147T5; Q15290; Q6DKH4; Q6P4C2; Q6YNC9; Q7Z6E8; Q7Z6E9; Q8N0V2; Q96PH3; Q9H3I8; Q9H5M5; Q9NPX4"	""	"RHOBTB1 GTPase cycle; Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"531.8"	"469.5"	"615.1"	"671.9"	"554.5"	"557.9"	"814.8"	"831.8"	"1058.8"	"1678.3"	"2127.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNS2"	"COP9 signalosome complex subunit 3 OS=Homo sapiens OX=9606 GN=COPS3 PE=1 SV=3"	"0.000"	""	"17"	"5"	"15"	"5"	"423"	"47.8"	"6.65"	"3452.59"	"28.09"	"5"	"4"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399"	"8533"	"ENSG00000141030"	"COPS3"	"B2R683; B4DY81; hsa:8533; O43191; Q7LDR6; Q9UNS2"	"Ciliary landscape; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"6"	"0"	"123.2"	"119.3"	"134.6"	"174.9"	"128.2"	"152.0"	"347.2"	"378.5"	"507.1"	"1169.2"	"1838.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23528"	"Cofilin-1 OS=Homo sapiens OX=9606 GN=CFL1 PE=1 SV=3"	"0.000"	""	"46"	"8"	"16"	"8"	"166"	"18.5"	"8.09"	"3433.72"	"28.01"	"8"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00241"	"1072"	"ENSG00000172757"	"CFL1"	"B3KUQ1; hsa:1072; P23528; Q53Y87; Q9UCA2"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway"	"Platelet degranulation ; Regulation of actin dynamics for phagocytic cup formation; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; EPHB-mediated forward signaling; Sema3A PAK dependent Axon repulsion; RHO GTPases Activate ROCKs"	"15"	"0"	"603.1"	"494.1"	"840.1"	"1382.1"	"541.7"	"453.0"	"906.8"	"1009.5"	"1234.1"	"2738.2"	"4188.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY77"	"Polymerase delta-interacting protein 3 OS=Homo sapiens OX=9606 GN=POLDIP3 PE=1 SV=2"	"0.000"	""	"21"	"5"	"9"	"5"	"421"	"46.1"	"9.99"	"1468.54"	"27.98"	"3"	"5"	"other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"84271"	"ENSG00000100227"	"POLDIP3"	"A8K6F8; A8K6V9; hsa:84271; Q009A7; Q5H972; Q6PGN6; Q7Z6Z0; Q9BY77; Q9NSP5; Q9NSP6"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"3"	"0"	"234.3"	"229.2"	"294.4"	"335.4"	"231.0"	"224.9"	"375.8"	"370.9"	"436.5"	"799.6"	"1149.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G61"	"Diphosphoinositol polyphosphate phosphohydrolase 3-beta OS=Homo sapiens OX=9606 GN=NUDT11 PE=1 SV=1"	"0.000"	""	"47"	"7"	"13"	"1"	"164"	"18.5"	"5.99"	"2572.04"	"27.93"	"5"	"6"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"55190"	"ENSG00000196368"	"NUDT11"	"hsa:55190; Q96G61; Q9NVN0"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"18.9"	"8.8"	"26.2"	"32.6"	"26.0"	"26.0"	"103.3"	"108.9"	"195.2"	"457.4"	"609.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00505"	"Importin subunit alpha-4 OS=Homo sapiens OX=9606 GN=KPNA3 PE=1 SV=2"	"0.000"	""	"16"	"5"	"9"	"4"	"521"	"57.8"	"4.94"	"1446.15"	"27.91"	"3"	"5"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3839"	"ENSG00000102753"	"KPNA3"	"hsa:3839; O00191; O00505; O43195; Q5JVM9; Q8IYQ9; Q96AA7"	""	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"2"	"1"	"190.5"	"168.0"	"227.0"	"280.7"	"192.0"	"179.6"	"362.3"	"385.8"	"528.9"	"1529.5"	"2563.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19525"	"Interferon-induced, double-stranded RNA-activated protein kinase OS=Homo sapiens OX=9606 GN=EIF2AK2 PE=1 SV=2"	"0.000"	""	"13"	"6"	"15"	"6"	"551"	"62.1"	"8.40"	"2715.34"	"27.90"	"6"	"6"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;kinase activity;other molecular function"	"Pf00035, Pf00069"	"5610"	"ENSG00000055332"	"EIF2AK2"	"A8K3P0; D6W584; E9PC80; hsa:5610; P19525; Q52M43; Q7Z6F6; Q9UIR4"	"Translation factors; Alzheimer's disease and miRNA effects; Ebola virus infection in host; Measles virus infection; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; Alzheimer's disease; Roles of ceramides in development of insulin resistance; Type II interferon signaling"	"ISG15 antiviral mechanism; Interferon alpha/beta signaling; Inhibition of PKR"	"12"	"0"	"284.6"	"284.0"	"347.1"	"461.6"	"304.0"	"330.0"	"586.7"	"631.4"	"1005.4"	"2664.0"	"3781.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05388"	"60S acidic ribosomal protein P0 OS=Homo sapiens OX=9606 GN=RPLP0 PE=1 SV=1"	"0.000"	""	"27"	"7"	"14"	"7"	"317"	"34.3"	"5.97"	"3090.03"	"27.82"	"7"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00428, Pf00466, Pf17777"	"6175"	"ENSG00000089157"	"RPLP0"	"hsa:6175; P05388; Q3B7A4; Q9BVK4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"420.1"	"362.7"	"492.7"	"650.2"	"372.8"	"370.8"	"738.8"	"798.7"	"1076.5"	"2811.7"	"4739.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99543"	"DnaJ homolog subfamily C member 2 OS=Homo sapiens OX=9606 GN=DNAJC2 PE=1 SV=4"	"0.000"	""	"16"	"8"	"14"	"8"	"621"	"72.0"	"8.70"	"2533.78"	"27.66"	"7"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00226, Pf00249, Pf16717"	"27000"	"ENSG00000105821"	"DNAJC2"	"A4VCI0; hsa:27000; Q99543; Q9BVX1"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"373.6"	"356.3"	"426.2"	"474.2"	"350.4"	"337.5"	"705.4"	"751.2"	"1103.4"	"2373.6"	"2905.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07666"	"KH domain-containing, RNA-binding, signal transduction-associated protein 1 OS=Homo sapiens OX=9606 GN=KHDRBS1 PE=1 SV=1"	"0.000"	""	"13"	"4"	"12"	"4"	"443"	"48.2"	"8.66"	"2511.65"	"27.64"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16274, Pf16568"	"10657"	"ENSG00000121774"	"KHDRBS1"	"D3DPP3; hsa:10657; Q07666; Q6PJX7; Q8NB97; Q99760"	"Leptin signaling pathway; Primary ovarian insufficiency"	"PTK6 Regulates Proteins Involved in RNA Processing"	"3"	"0"	"422.2"	"752.1"	"466.5"	"647.3"	"414.5"	"452.7"	"770.6"	"890.4"	"1089.3"	"1854.3"	"2028.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95292"	"Vesicle-associated membrane protein-associated protein B/C OS=Homo sapiens OX=9606 GN=VAPB PE=1 SV=3"	"0.000"	""	"19"	"4"	"12"	"3"	"243"	"27.2"	"7.30"	"2615.83"	"27.59"	"4"	"4"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9217"	"ENSG00000124164"	"VAPB"	"A2A2F2; hsa:9217; O95292; O95293; Q9P0H0"	"Ciliary landscape"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RHOD GTPase cycle; Sphingolipid de novo biosynthesis"	"7"	"0"	"62.2"	"47.4"	"78.8"	"82.0"	"58.2"	"60.7"	"179.8"	"195.5"	"361.0"	"1001.6"	"1642.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75150"	"E3 ubiquitin-protein ligase BRE1B OS=Homo sapiens OX=9606 GN=RNF40 PE=1 SV=5"	"0.000"	""	"8"	"7"	"14"	"5"	"1001"	"113.6"	"6.29"	"2834.49"	"27.55"	"7"	"7"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00097"	"9810"	"ENSG00000103549"	"RNF40"	"A0A024QZG0; hsa:9810; O75150; Q6AHZ6; Q6N005; Q7L3T6; Q8N615; Q96T18; Q9BSV9; Q9HC82"	"ATM signaling in development and disease"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	"282.6"	"238.6"	"300.9"	"360.0"	"252.4"	"263.7"	"475.9"	"528.6"	"751.9"	"1751.8"	"2405.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WU90"	"Zinc finger CCCH domain-containing protein 15 OS=Homo sapiens OX=9606 GN=ZC3H15 PE=1 SV=1"	"0.000"	""	"20"	"9"	"18"	"9"	"426"	"48.6"	"5.31"	"3949.21"	"27.53"	"9"	"8"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00642, Pf16543"	"55854"	"ENSG00000065548"	"ZC3H15"	"B4DMW2; D3DPG7; hsa:55854; Q5QTQ4; Q8WU90; Q8WZ06; Q9NUZ3; Q9NZ37; Q9P079"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"1058.7"	"968.6"	"1103.6"	"1267.8"	"1054.9"	"956.8"	"1534.1"	"1509.8"	"1868.7"	"3746.9"	"3794.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35232"	"Prohibitin OS=Homo sapiens OX=9606 GN=PHB PE=1 SV=1"	"0.000"	""	"37"	"9"	"17"	"9"	"272"	"29.8"	"5.76"	"3903.94"	"27.53"	"8"	"8"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"5245"	"ENSG00000167085"	"PHB1"	"B4DY47; hsa:5245; P35232; Q4VBQ0"	""	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Processing of SMDT1"	"5"	"0"	"663.5"	"662.1"	"641.0"	"817.0"	"608.4"	"636.9"	"1047.2"	"1078.8"	"1393.4"	"3395.9"	"4354.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36578"	"60S ribosomal protein L4 OS=Homo sapiens OX=9606 GN=RPL4 PE=1 SV=5"	"0.000"	""	"18"	"7"	"16"	"7"	"427"	"47.7"	"11.06"	"3314.13"	"27.34"	"7"	"6"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00573, Pf14374"	"6124"	"ENSG00000174444"	"RPL4"	"A8K502; hsa:6124; P36578; P39029; Q4VBR0; Q969Z9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"646.5"	"740.7"	"732.0"	"962.1"	"644.3"	"638.3"	"1138.5"	"1192.3"	"1481.7"	"3568.3"	"5181.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15022"	"Polycomb protein SUZ12 OS=Homo sapiens OX=9606 GN=SUZ12 PE=1 SV=3"	"0.000"	""	"7"	"3"	"9"	"3"	"739"	"83.0"	"8.81"	"2060.09"	"27.32"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf09733"	"23512"	"ENSG00000178691"	"SUZ12"	"hsa:23512; Q15022; Q96BD9"	"Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"HCMV Early Events; Oxidative Stress Induced Senescence; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PRC2 methylates histones and DNA; Defective pyroptosis; SUMOylation of chromatin organization proteins; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; PKMTs methylate histone lysines"	"14"	"0"	"68.3"	"71.7"	"90.1"	"99.2"	"78.8"	"77.6"	"140.3"	"143.2"	"228.6"	"605.9"	"707.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKX7"	"Nuclear pore complex protein Nup50 OS=Homo sapiens OX=9606 GN=NUP50 PE=1 SV=2"	"0.000"	""	"19"	"6"	"11"	"6"	"468"	"50.1"	"7.06"	"2570.38"	"27.29"	"5"	"4"	"transport"	"other membranes;nucleus"	""	"Pf00638, Pf08911"	"10762"	"ENSG00000093000"	"NUP50"	"B1AHA4; B2RB15; hsa:10762; O75644; Q8N6V5; Q9NPM9; Q9NPR6; Q9P1K5; Q9UKX7"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; Regulation of HSF1-mediated heat shock response; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transport of Mature mRNA derived from an Intron-Containing Transcript; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus"	"28"	"0"	"266.5"	"229.6"	"318.3"	"343.0"	"256.9"	"261.7"	"458.7"	"417.9"	"600.5"	"1802.8"	"2954.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5X1"	"Sorting nexin-9 OS=Homo sapiens OX=9606 GN=SNX9 PE=1 SV=1"	"0.000"	""	"19"	"7"	"13"	"7"	"595"	"66.6"	"5.58"	"2592.51"	"27.17"	"6"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00018, Pf00787, Pf10456"	"51429"	"ENSG00000130340"	"SNX9"	"hsa:51429; Q9BSI7; Q9BVM1; Q9UJH6; Q9UP20; Q9Y5X1"	""	"Clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis"	"2"	"0"	"177.7"	"153.4"	"237.7"	"316.5"	"339.6"	"594.5"	"1509.1"	"1623.5"	"1447.0"	"1013.3"	"1082.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13667"	"Protein disulfide-isomerase A4 OS=Homo sapiens OX=9606 GN=PDIA4 PE=1 SV=2"	"0.000"	""	"16"	"8"	"13"	"7"	"645"	"72.9"	"5.07"	"1892.55"	"27.08"	"5"	"8"	"protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"9601"	"ENSG00000155660"	"PDIA4"	"A8K4K6; hsa:9601; P13667; Q549T6"	""	""	"0"	"1"	"850.0"	"856.7"	"966.6"	"1336.4"	"861.9"	"837.0"	"1198.9"	"1239.0"	"1292.2"	"2103.6"	"2616.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13595"	"Transformer-2 protein homolog alpha OS=Homo sapiens OX=9606 GN=TRA2A PE=1 SV=1"	"0.000"	""	"17"	"7"	"17"	"7"	"282"	"32.7"	"11.27"	"2537.60"	"27.03"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"29896"	"ENSG00000164548"	"TRA2A"	"B4DQI6; B4DUA9; E9PD75; hsa:29896; Q13595"	"Orexin receptor pathway"	""	"1"	"0"	"844.3"	"1143.1"	"723.0"	"1103.5"	"681.0"	"715.7"	"1166.4"	"1330.6"	"1411.8"	"2620.7"	"3624.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3I0"	"RNA-splicing ligase RtcB homolog OS=Homo sapiens OX=9606 GN=RTCB PE=1 SV=1"	"0.000"	""	"18"	"9"	"18"	"9"	"505"	"55.2"	"7.23"	"3109.66"	"27.00"	"9"	"7"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01139"	"51493"	"ENSG00000100220"	"RTCB"	"B2R6A8; hsa:51493; Q6IAI0; Q9BWL4; Q9NTH1; Q9P037; Q9P0J3; Q9Y3I0"	"Unfolded protein response"	"tRNA processing in the nucleus"	"2"	"0"	"1066.9"	"1023.1"	"1098.5"	"1330.0"	"954.3"	"971.9"	"1620.4"	"1624.5"	"2264.2"	"3981.7"	"5002.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24752"	"Acetyl-CoA acetyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAT1 PE=1 SV=1"	"0.000"	""	"18"	"7"	"14"	"7"	"427"	"45.2"	"8.85"	"2213.77"	"26.90"	"5"	"7"	"other metabolic processes;stress response;developmental processes;other biological processes"	"mitochondrion;ER/Golgi"	"other molecular function"	"Pf00108, Pf02803"	"38"	"ENSG00000075239"	"ACAT1"	"B2R6H1; G3XAB4; hsa:38; P24752; Q96FG8"	"Fatty acid beta-oxidation; Tryptophan metabolism; SARS-CoV-2 and COVID-19 pathway"	"Branched-chain amino acid catabolism; Utilization of Ketone Bodies; Synthesis of Ketone Bodies"	"6"	"0"	"240.6"	"257.9"	"281.8"	"358.4"	"243.7"	"245.2"	"496.1"	"532.0"	"841.6"	"3146.0"	"5298.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFP7"	"Diphosphoinositol polyphosphate phosphohydrolase 3-alpha OS=Homo sapiens OX=9606 GN=NUDT10 PE=1 SV=1"	"0.000"	""	"47"	"7"	"13"	"1"	"164"	"18.5"	"5.68"	"2346.38"	"26.80"	"5"	"6"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00293"	"170685"	"ENSG00000122824"	"NUDT10"	"A8K7D7; D3DX69; hsa:170685; Q86VK1; Q86VR0; Q8NFP7"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"6"	"134.3"	"119.7"	"194.1"	"239.7"	"213.6"	"380.9"	"1176.0"	"1354.8"	"1858.8"	"4329.7"	"5223.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43246"	"DNA mismatch repair protein Msh2 OS=Homo sapiens OX=9606 GN=MSH2 PE=1 SV=1"	"0.000"	""	"12"	"7"	"13"	"7"	"934"	"104.7"	"5.77"	"2074.19"	"26.80"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05190, Pf05192"	"4436"	"ENSG00000095002"	"MSH2"	"B4E2Z2; hsa:4436; O75488; P43246"	"RAC1/PAK1/p38/MMP2 pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ciliary landscape; DNA repair pathways, full network; p53 transcriptional gene network; DNA mismatch repair"	"TP53 Regulates Transcription of DNA Repair Genes; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"12"	"0"	"279.8"	"226.7"	"297.0"	"364.7"	"229.9"	"229.2"	"433.3"	"463.0"	"624.5"	"1458.0"	"2084.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06730"	"Eukaryotic translation initiation factor 4E OS=Homo sapiens OX=9606 GN=EIF4E PE=1 SV=2"	"0.000"	""	"37"	"8"	"15"	"8"	"217"	"25.1"	"6.15"	"2874.11"	"26.78"	"8"	"7"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01652"	"1977"	"ENSG00000151247"	"EIF4E"	"B7Z6V1; D6RCQ6; hsa:1977; P06730; Q96E95"	"Translation factors; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Interleukin-1 (IL-1) structural pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prader-Willi and Angelman syndrome; PI3K-Akt signaling pathway; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Hypertrophy model; Interferon type I signaling pathways"	"Deadenylation of mRNA; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling"	"31"	"0"	"159.0"	"136.2"	"205.3"	"243.6"	"144.5"	"183.8"	"653.3"	"698.3"	"1361.2"	"4546.2"	"6547.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25398"	"40S ribosomal protein S12 OS=Homo sapiens OX=9606 GN=RPS12 PE=1 SV=3"	"0.000"	""	"47"	"7"	"11"	"7"	"132"	"14.5"	"7.21"	"2094.08"	"26.74"	"4"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6206"	"ENSG00000112306"	"RPS12"	"hsa:6206; P25398; Q76M58"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"498.0"	"519.9"	"564.2"	"633.8"	"477.1"	"361.5"	"833.7"	"889.5"	"1152.2"	"2874.9"	"5733.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75521"	"Enoyl-CoA delta isomerase 2, mitochondrial OS=Homo sapiens OX=9606 GN=ECI2 PE=1 SV=4"	"0.000"	""	"20"	"6"	"10"	"6"	"394"	"43.6"	"9.00"	"1787.06"	"26.71"	"4"	"6"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00378, Pf00887"	"10455"	"ENSG00000198721"	"ECI2"	"hsa:10455; O75521; Q5JYK5; Q5JYK7; Q7L124; Q8N0X0; Q9BUE9; Q9H0T9; Q9NQH1; Q9NYH7; Q9UN55"	""	""	"0"	"0"	"387.3"	"405.3"	"440.5"	"446.5"	"385.0"	"435.0"	"900.5"	"931.2"	"1428.5"	"5184.5"	"7256.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0L0"	"Vesicle-associated membrane protein-associated protein A OS=Homo sapiens OX=9606 GN=VAPA PE=1 SV=3"	"0.000"	""	"35"	"6"	"14"	"5"	"249"	"27.9"	"8.62"	"2676.49"	"26.62"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00635"	"9218"	"ENSG00000101558"	"VAPA"	"A6NDZ0; D3DUI3; hsa:9218; O75453; Q5U0E7; Q9P0L0; Q9UBZ2"	"Exercise-induced circadian regulation; Cholesterol metabolism"	"Neutrophil degranulation; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane; Sphingolipid de novo biosynthesis"	"5"	"1"	"186.1"	"175.1"	"218.1"	"226.7"	"187.0"	"187.4"	"437.4"	"483.6"	"787.4"	"2043.3"	"2876.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05141"	"ADP/ATP translocase 2 OS=Homo sapiens OX=9606 GN=SLC25A5 PE=1 SV=7"	"0.000"	""	"28"	"8"	"17"	"3"	"298"	"32.8"	"9.69"	"3727.03"	"26.57"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"292"	"ENSG00000005022"	"SLC25A5"	"B2RCV1; hsa:292; O43350; P05141"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"5"	"5"	"663.9"	"649.4"	"729.4"	"976.0"	"636.4"	"593.6"	"1218.7"	"1278.5"	"1757.3"	"4629.0"	"6198.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16836"	"Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=HADH PE=1 SV=3"	"0.000"	""	"32"	"8"	"15"	"8"	"314"	"34.3"	"8.85"	"2297.18"	"26.54"	"6"	"7"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00725, Pf02737"	"3033"	"ENSG00000138796"	"HADH"	"hsa:3033; J3KQ17; O00324; O00397; O00753; Q16836; Q4W5B4"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; Amino acid metabolism; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"11"	"0"	"350.7"	"343.4"	"417.6"	"499.9"	"352.3"	"396.8"	"698.3"	"735.5"	"1184.7"	"4466.4"	"6346.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2E9"	"Ribosome-binding protein 1 OS=Homo sapiens OX=9606 GN=RRBP1 PE=1 SV=5"	"0.000"	""	"21"	"11"	"18"	"10"	"1410"	"152.4"	"8.60"	"3854.20"	"26.38"	"10"	"8"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi;translational apparatus"	"other molecular function"	"Pf05104"	"6238"	"ENSG00000125844"	"RRBP1"	"A0A0A0MRV0; A2A2S6; A6NCN6; hsa:6238; O75300; O75301; Q5W165; Q96SB2; Q9BWP1; Q9H476; Q9P2E9"	"Ectoderm differentiation"	"Signaling by ALK fusions and activated point mutants"	"2"	"0"	"632.1"	"622.1"	"691.8"	"804.7"	"689.4"	"642.7"	"933.5"	"953.3"	"1260.5"	"2220.5"	"2804.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUP9"	"Protein lin-7 homolog C OS=Homo sapiens OX=9606 GN=LIN7C PE=1 SV=1"	"0.000"	""	"28"	"8"	"16"	"4"	"197"	"21.8"	"8.43"	"3095.62"	"26.35"	"8"	"7"	"cell-cell signaling;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf02828"	"55327"	"ENSG00000148943"	"LIN7C"	"hsa:55327; Q9NUP9"	""	"Neurexins and neuroligins; Assembly and cell surface presentation of NMDA receptors; Dopamine Neurotransmitter Release Cycle"	"3"	"4"	"882.5"	"807.4"	"1003.4"	"1162.8"	"801.1"	"785.6"	"1561.1"	"1603.5"	"2465.1"	"6276.8"	"8014.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99623"	"Prohibitin-2 OS=Homo sapiens OX=9606 GN=PHB2 PE=1 SV=2"	"0.000"	""	"23"	"7"	"17"	"7"	"299"	"33.3"	"9.83"	"3448.50"	"26.34"	"7"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01145"	"11331"	"ENSG00000215021"	"PHB2"	"B4DP75; hsa:11331; Q2YDA4; Q7KYU3; Q92978; Q99623"	""	"Processing of SMDT1"	"1"	"0"	"956.8"	"1041.1"	"1005.3"	"1182.8"	"914.1"	"973.0"	"1438.9"	"1471.7"	"1861.8"	"3880.8"	"4941.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16775"	"Hydroxyacylglutathione hydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=HAGH PE=1 SV=2"	"0.000"	""	"26"	"5"	"11"	"5"	"308"	"33.8"	"8.12"	"2272.28"	"26.31"	"3"	"4"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00753, Pf16123"	"3029"	"ENSG00000063854"	"HAGH"	"A8K290; B4DP33; B4DRA7; E7EN93; hsa:3029; Q16775"	""	""	"0"	"0"	"238.1"	"221.1"	"266.5"	"320.8"	"219.5"	"232.1"	"359.8"	"364.2"	"427.4"	"909.1"	"1372.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI48"	"Aspartate--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=DARS2 PE=1 SV=1"	"0.000"	""	"16"	"9"	"16"	"9"	"645"	"73.5"	"8.02"	"2707.35"	"26.14"	"8"	"8"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00152, Pf01336, Pf02938"	"55157"	"ENSG00000117593"	"DARS2"	"hsa:55157; Q6PI48"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"364.4"	"348.4"	"443.8"	"543.7"	"346.9"	"296.6"	"614.6"	"662.8"	"919.1"	"2215.9"	"3146.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43768"	"Alpha-endosulfine OS=Homo sapiens OX=9606 GN=ENSA PE=1 SV=1"	"0.000"	""	"59"	"6"	"13"	"6"	"121"	"13.4"	"7.24"	"2741.24"	"26.04"	"6"	"6"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"2029"	"ENSG00000143420"	"ENSA"	"A8K1Z9; E9PB69; hsa:2029; O43768; Q5T5H2; Q68D48; Q6FHW0; Q6IAM4; Q6NUL2; Q6VUC6; Q6VUC7; Q6VUC8; Q6VUC9; Q6VUD0; Q6VUD1; Q9NRZ0"	""	"MASTL Facilitates Mitotic Progression"	"1"	"0"	"169.5"	"153.5"	"225.3"	"253.0"	"178.2"	"185.4"	"616.9"	"711.6"	"1294.9"	"4159.1"	"5156.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5S9"	"RNA-binding protein 8A OS=Homo sapiens OX=9606 GN=RBM8A PE=1 SV=1"	"0.000"	""	"31"	"3"	"11"	"3"	"174"	"19.9"	"5.72"	"2999.35"	"25.94"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"9939"	"ENSG00000265241"	"RBM8A"	"B3KQI9; hsa:9939; Q6FHD1; Q6IQ40; Q9GZX8; Q9NZI4; Q9Y5S9"	""	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"6"	"0"	"129.4"	"175.3"	"116.2"	"164.6"	"121.1"	"136.9"	"188.7"	"199.6"	"240.6"	"533.0"	"871.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T37"	"RNA-binding protein 15 OS=Homo sapiens OX=9606 GN=RBM15 PE=1 SV=2"	"0.000"	""	"10"	"8"	"14"	"7"	"977"	"107.1"	"10.08"	"2586.89"	"25.86"	"7"	"7"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"64783"	"ENSG00000162775"	"RBM15"	"A1A693; hsa:64783; Q3ZB86; Q4V760; Q5D058; Q5T613; Q86VW9; Q96PE4; Q96SC5; Q96SC6; Q96SC9; Q96SD0; Q96T37; Q96T38; Q9BRA5; Q9H6R8; Q9H9Y0"	""	""	"0"	"1"	"775.1"	"628.9"	"732.1"	"953.9"	"720.2"	"798.9"	"1510.7"	"1604.4"	"1957.0"	"3166.8"	"3612.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99426"	"Tubulin-folding cofactor B OS=Homo sapiens OX=9606 GN=TBCB PE=1 SV=2"	"0.000"	""	"26"	"5"	"10"	"5"	"244"	"27.3"	"5.15"	"1781.36"	"25.85"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf01302, Pf14560"	"1155"	"ENSG00000105254"	"TBCB"	"hsa:1155; O00111; O00674; O14728; Q6FGY5; Q99426"	""	"Post-chaperonin tubulin folding pathway"	"1"	"0"	"127.0"	"126.3"	"193.4"	"188.6"	"122.9"	"107.3"	"253.0"	"278.3"	"356.3"	"2078.1"	"5259.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NSI4"	"RPA-related protein RADX OS=Homo sapiens OX=9606 GN=RADX PE=1 SV=2"	"0.000"	""	"9"	"7"	"12"	"7"	"855"	"97.5"	"8.41"	"1994.74"	"25.74"	"5"	"7"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf17659"	"55086"	"ENSG00000147231"	"RADX"	"H7BY89; hsa:55086; Q4G0L7; Q5JQS1; Q5JRF9; Q6NSI4; Q6PHY5; Q6PII9; Q6PJU8; Q9H7W5; Q9NWA6"	""	""	"0"	"0"	"228.9"	"237.1"	"311.3"	"347.7"	"276.3"	"262.3"	"438.4"	"443.4"	"583.7"	"1255.7"	"1652.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06576"	"ATP synthase subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1B PE=1 SV=3"	"0.000"	""	"10"	"5"	"12"	"5"	"529"	"56.5"	"5.40"	"2755.87"	"25.74"	"4"	"4"	"other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf00006, Pf02874"	"506"	"ENSG00000110955"	"ATP5F1B"	"A8K4X0; hsa:506; P06576; Q14283"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Transcriptional activation of mitochondrial biogenesis; Mitochondrial protein import; Cristae formation; Formation of ATP by chemiosmotic coupling"	"7"	"0"	"337.0"	"320.9"	"380.4"	"534.5"	"286.0"	"330.7"	"663.5"	"707.6"	"1040.0"	"3210.3"	"5111.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13442"	"28 kDa heat- and acid-stable phosphoprotein OS=Homo sapiens OX=9606 GN=PDAP1 PE=1 SV=1"	"0.000"	""	"46"	"8"	"14"	"8"	"181"	"20.6"	"8.87"	"3460.23"	"25.72"	"8"	"6"	"signal transduction"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf10252"	"11333"	"ENSG00000106244"	"PDAP1"	"D6W5S5; hsa:11333; Q13442; Q92906"	""	"Neutrophil degranulation"	"1"	"0"	"922.7"	"781.5"	"900.2"	"970.1"	"859.4"	"847.2"	"1566.8"	"1639.3"	"2351.4"	"3002.7"	"2566.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P99999"	"Cytochrome c OS=Homo sapiens OX=9606 GN=CYCS PE=1 SV=2"	"0.000"	""	"58"	"8"	"16"	"8"	"105"	"11.7"	"9.57"	"3664.50"	"25.67"	"7"	"6"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00034"	"54205"	"ENSG00000172115"	"CYCS"	"A4D166; B2R4I1; hsa:54205; P00001; P99999; Q6NUR2; Q6NX69; Q96BV4"	"miRNA regulation of DNA damage response; Apoptosis modulation and signaling; Alzheimer's disease and miRNA effects; AGE/RAGE pathway; Parkinson's disease pathway; Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; VEGFA-VEGFR2 signaling; Oxidative damage response; NO/cGMP/PKG mediated neuroprotection; Chromosomal and microsatellite instability in colorectal cancer ; Non-small cell lung cancer; Acute viral myocarditis; Nonalcoholic fatty liver disease; Measles virus infection; Small cell lung cancer; Hepatitis B infection; IL-18 signaling pathway; Pleural mesothelioma; Complement system in neuronal development and plasticity; Alzheimer's disease; DNA damage response"	"Respiratory electron transport; Detoxification of Reactive Oxygen Species; Transcriptional activation of mitochondrial biogenesis; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; Regulation of the apoptosome activity; Release of apoptotic factors from the mitochondria; Pyroptosis"	"36"	"0"	"1152.5"	"1694.8"	"1095.5"	"1207.2"	"1904.0"	"1155.2"	"1572.3"	"1537.9"	"1555.9"	"2021.7"	"2376.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99567"	"Nuclear pore complex protein Nup88 OS=Homo sapiens OX=9606 GN=NUP88 PE=1 SV=2"	"0.000"	""	"12"	"6"	"12"	"6"	"741"	"83.5"	"5.69"	"2703.33"	"25.64"	"6"	"6"	"cell cycle OR cell proliferation;other metabolic processes;transport"	"cytosol;nucleus"	"other molecular function"	"Pf10168"	"4927"	"ENSG00000108559"	"NUP88"	"D3DTM2; hsa:4927; Q99567; Q9BWE5"	"Ciliary landscape"	"HCMV Early Events; ISG15 antiviral mechanism; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; HCMV Late Events; Regulation of HSF1-mediated heat shock response; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; Nuclear Pore Complex (NPC) Disassembly; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"29"	"0"	"319.6"	"307.7"	"335.1"	"433.7"	"290.9"	"303.3"	"540.9"	"593.1"	"788.2"	"1808.9"	"2606.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60231"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase DHX16 OS=Homo sapiens OX=9606 GN=DHX16 PE=1 SV=2"	"0.000"	""	"10"	"9"	"15"	"9"	"1041"	"119.2"	"6.80"	"3152.94"	"25.63"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"8449"	"ENSG00000204560; ENSG00000206486; ENSG00000226171; ENSG00000231377; ENSG00000233049; ENSG00000233418; ENSG00000233561"	"DHX16"	"hsa:8449; O60231; O60322; Q5JP45; Q969X7; Q96QC1"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"302.2"	"273.1"	"303.5"	"397.1"	"262.6"	"287.8"	"554.9"	"633.1"	"1087.5"	"1968.1"	"2283.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A72"	"Protein mago nashi homolog 2 OS=Homo sapiens OX=9606 GN=MAGOHB PE=1 SV=1"	"0.000"	""	"44"	"6"	"11"	"6"	"148"	"17.3"	"6.39"	"2050.44"	"25.51"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf02792"	"55110"	"ENSG00000111196"	"MAGOHB"	"hsa:55110; Q96A72"	""	"Regulation of expression of SLITs and ROBOs; mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"6"	"0"	"230.3"	"225.7"	"283.1"	"373.4"	"235.2"	"255.3"	"398.0"	"407.3"	"536.0"	"1424.2"	"2401.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75792"	"Ribonuclease H2 subunit A OS=Homo sapiens OX=9606 GN=RNASEH2A PE=1 SV=2"	"0.000"	""	"24"	"5"	"12"	"5"	"299"	"33.4"	"5.25"	"2594.78"	"25.49"	"5"	"5"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01351"	"10535"	"ENSG00000104889"	"RNASEH2A"	"B2RCY1; hsa:10535; O75792; Q96F11"	""	""	"0"	"0"	"204.9"	"172.9"	"265.4"	"296.3"	"195.7"	"208.2"	"494.7"	"507.0"	"1021.1"	"2813.1"	"3579.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12959"	"Disks large homolog 1 OS=Homo sapiens OX=9606 GN=DLG1 PE=1 SV=2"	"0.000"	""	"9"	"6"	"10"	"6"	"904"	"100.4"	"5.76"	"1274.98"	"25.48"	"4"	"6"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00018, Pf00595, Pf00625, Pf09058, Pf10600, Pf10608"	"1739"	"ENSG00000075711"	"DLG1"	"A5YKK7; B4DGU1; B4DGZ8; B7ZMM0; B9EIQ5; D3DXB8; D3DXB9; E7EWL7; E9PG21; hsa:1739; Q12958; Q12959"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Disruption of postsynaptic signaling by CNV; 3q29 copy number variation syndrome"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"14"	"0"	"194.0"	"176.0"	"191.3"	"237.0"	"168.3"	"172.5"	"412.7"	"437.7"	"792.1"	"1811.0"	"2142.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62249"	"40S ribosomal protein S16 OS=Homo sapiens OX=9606 GN=RPS16 PE=1 SV=2"	"0.000"	""	"34"	"6"	"16"	"6"	"146"	"16.4"	"10.21"	"2906.35"	"25.42"	"6"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00380"	"6217"	"ENSG00000105193"	"RPS16"	"B2RDD5; hsa:6217; P17008; P62249"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery"	"19"	"0"	"648.1"	"704.3"	"787.7"	"982.2"	"664.3"	"738.3"	"1063.5"	"1097.1"	"1445.8"	"3200.5"	"4302.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62701"	"40S ribosomal protein S4, X isoform OS=Homo sapiens OX=9606 GN=RPS4X PE=1 SV=2"	"0.000"	""	"29"	"10"	"17"	"10"	"263"	"29.6"	"10.15"	"2458.84"	"25.41"	"8"	"8"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf00900, Pf01479, Pf08071, Pf16121"	"6191"	"ENSG00000198034"	"RPS4X"	"hsa:6191; P12631; P12750; P27576; P55831; P62701; Q14727; Q6IPY4"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1210.8"	"1163.0"	"1288.4"	"1600.9"	"1062.0"	"1073.2"	"1832.7"	"1941.9"	"2317.2"	"5272.3"	"8327.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30405"	"Peptidyl-prolyl cis-trans isomerase F, mitochondrial OS=Homo sapiens OX=9606 GN=PPIF PE=1 SV=1"	"0.000"	""	"34"	"7"	"17"	"6"	"207"	"22.0"	"9.38"	"2967.20"	"25.40"	"6"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf00160"	"10105"	"ENSG00000108179"	"PPIF"	"hsa:10105; P30405; Q2YDB7; Q5W131"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	""	"2"	"1"	"1756.8"	"1755.4"	"2015.1"	"2423.6"	"1580.5"	"1640.0"	"2475.5"	"2570.9"	"2834.5"	"5444.4"	"7014.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2D5"	"A-kinase anchor protein 2 OS=Homo sapiens OX=9606 GN=AKAP2 PE=1 SV=3"	"0.000"	""	"9"	"6"	"13"	"6"	"859"	"94.6"	"5.11"	"3002.48"	"25.36"	"6"	"5"	""	""	""	"Pf15304"	"445815"	""	"AKAP2"	"B1ALX9; B2RTU4; B3KQ00; B4DTZ2; B7ZW07; B9EJB5; Q9UG26; Q9Y2D5"	""	""	"0"	"0"	"568.8"	"560.2"	"642.9"	"684.7"	"527.1"	"594.5"	"781.5"	"798.1"	"934.9"	"2117.2"	"2615.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15160"	"DNA-directed RNA polymerases I and III subunit RPAC1 OS=Homo sapiens OX=9606 GN=POLR1C PE=1 SV=1"	"0.000"	""	"27"	"7"	"12"	"7"	"346"	"39.2"	"5.50"	"1975.68"	"25.32"	"5"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"9533"	"ENSG00000171453"	"POLR1C"	"hsa:9533; O15160; O75395; Q5JTE3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"15"	"0"	"187.6"	"166.7"	"210.3"	"274.9"	"193.6"	"191.8"	"550.3"	"669.5"	"1030.4"	"2517.5"	"3196.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62304"	"Small nuclear ribonucleoprotein E OS=Homo sapiens OX=9606 GN=SNRPE PE=1 SV=1"	"0.000"	""	"55"	"4"	"13"	"4"	"92"	"10.8"	"9.44"	"2151.57"	"25.29"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6635"	"ENSG00000182004"	"SNRPE"	"B2R5B9; hsa:6635; P08578; P62304; Q15498; Q5BKT2"	"mRNA processing"	"mRNA Splicing - Major Pathway; snRNP Assembly; RNA Polymerase II Transcription Termination; SARS-CoV-2 modulates host translation machinery; mRNA Splicing - Minor Pathway; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"324.6"	"284.5"	"287.4"	"445.0"	"219.7"	"291.2"	"363.4"	"381.2"	"471.3"	"1068.0"	"1588.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAW4"	"Claspin OS=Homo sapiens OX=9606 GN=CLSPN PE=1 SV=3"	"0.000"	""	"8"	"7"	"13"	"7"	"1339"	"151.0"	"4.82"	"2658.39"	"25.29"	"6"	"7"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus"	"nucleic acid binding activity;other molecular function"	""	"63967"	"ENSG00000092853"	"CLSPN"	"A6NFL4; hsa:63967; Q1RMC6; Q2KHM3; Q5VYG0; Q6P6H5; Q8IWI1; Q9HAW4"	""	"Activation of ATR in response to replication stress; Ub-specific processing proteases; Processing of DNA double-strand break ends; Apoptotic cleavage of cellular proteins"	"4"	"0"	"431.7"	"366.0"	"466.4"	"559.3"	"400.0"	"384.1"	"512.1"	"541.0"	"572.1"	"749.6"	"862.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63244"	"Receptor of activated protein C kinase 1 OS=Homo sapiens OX=9606 GN=RACK1 PE=1 SV=3"	"0.000"	""	"21"	"7"	"12"	"7"	"317"	"35.1"	"7.69"	"1431.85"	"25.27"	"4"	"7"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;cytosol;mitochondrion;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;translation activity;other molecular function"	"Pf00400"	"10399"	"ENSG00000204628"	"RACK1"	"B3KTJ0; D3DWS0; hsa:10399; P25388; P63244; P99049; Q53HU2; Q5J8M6; Q5VLR4; Q6FH47"	"Androgen receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; VEGFA-VEGFR2 signaling; Measles virus infection; Angiotensin II receptor type 1 pathway; TROP2 regulatory signaling; Interferon type I signaling pathways"	"Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; TNFR1-mediated ceramide production"	"10"	"0"	"344.1"	"276.4"	"436.1"	"608.3"	"316.4"	"303.5"	"551.0"	"584.7"	"748.1"	"2045.7"	"4843.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92598"	"Heat shock protein 105 kDa OS=Homo sapiens OX=9606 GN=HSPH1 PE=1 SV=1"	"0.000"	""	"10"	"7"	"13"	"6"	"858"	"96.8"	"5.39"	"2116.23"	"25.15"	"6"	"7"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00012"	"10808"	"ENSG00000120694"	"HSPH1"	"B4DYH1; hsa:10808; O95739; Q5TBM6; Q5TBM7; Q5TBM8; Q92598; Q9UPC4"	""	"Regulation of HSF1-mediated heat shock response; Scavenging by Class F Receptors"	"2"	"0"	"351.6"	"347.8"	"410.2"	"555.3"	"362.7"	"359.9"	"546.5"	"619.4"	"690.9"	"1436.9"	"1881.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61247"	"40S ribosomal protein S3a OS=Homo sapiens OX=9606 GN=RPS3A PE=1 SV=2"	"0.000"	""	"33"	"10"	"21"	"10"	"264"	"29.9"	"9.73"	"4255.36"	"25.11"	"10"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01015"	"6189"	"ENSG00000145425"	"RPS3A"	"B2R4D4; D3DP05; hsa:6189; P33443; P49241; P61247"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"1284.0"	"1407.4"	"1384.7"	"1636.1"	"1254.1"	"1325.6"	"1884.0"	"1990.8"	"2286.8"	"4576.4"	"6367.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42765"	"3-ketoacyl-CoA thiolase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAA2 PE=1 SV=2"	"0.000"	""	"19"	"5"	"8"	"5"	"397"	"41.9"	"8.09"	"953.67"	"25.07"	"3"	"5"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"mitochondrion"	"other molecular function"	"Pf00108, Pf02803"	"10449"	"ENSG00000167315"	"ACAA2"	"hsa:10449; P42765; Q9BUT6"	"Fatty acid biosynthesis"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"143.0"	"135.8"	"189.9"	"239.3"	"142.7"	"132.9"	"310.6"	"332.4"	"604.8"	"1862.0"	"2762.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12931"	"Heat shock protein 75 kDa, mitochondrial OS=Homo sapiens OX=9606 GN=TRAP1 PE=1 SV=3"	"0.000"	""	"13"	"8"	"15"	"8"	"704"	"80.1"	"8.21"	"2798.08"	"25.06"	"8"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00183, Pf02518"	"10131"	"ENSG00000126602"	"TRAP1"	"B4DR68; D3DUC8; F5H897; hsa:10131; O43642; O75235; Q12931; Q9UHL5"	"TNF-alpha signaling pathway; Clock-controlled autophagy in bone metabolism"	"Respiratory electron transport"	"3"	"0"	"348.2"	"324.4"	"385.7"	"444.5"	"363.6"	"497.7"	"698.0"	"638.4"	"838.6"	"1617.4"	"2005.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EP5"	"DAZ-associated protein 1 OS=Homo sapiens OX=9606 GN=DAZAP1 PE=1 SV=1"	"0.000"	""	"16"	"6"	"15"	"6"	"407"	"43.4"	"8.56"	"3724.96"	"25.03"	"5"	"5"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"26528"	"ENSG00000071626"	"DAZAP1"	"hsa:26528; Q96EP5; Q96MJ3; Q9NRR9"	""	""	"0"	"0"	"909.5"	"868.4"	"1013.8"	"1231.6"	"975.7"	"734.5"	"1228.5"	"1246.2"	"1338.7"	"1903.4"	"2656.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48735"	"Isocitrate dehydrogenase [NADP], mitochondrial OS=Homo sapiens OX=9606 GN=IDH2 PE=1 SV=2"	"0.000"	""	"16"	"6"	"15"	"6"	"452"	"50.9"	"8.69"	"2948.84"	"24.95"	"6"	"5"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00180"	"3418"	"ENSG00000182054"	"IDH2"	"B2R6L6; B4DFL2; hsa:3418; P48735; Q96GT3"	"VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer; Cerebral organic acidurias, including diseases; TCA cycle (aka Krebs or citric acid cycle)"	"Transcriptional activation of mitochondrial biogenesis; Citric acid cycle (TCA cycle)"	"6"	"0"	"429.3"	"445.3"	"376.4"	"477.2"	"350.1"	"352.2"	"590.9"	"665.4"	"812.3"	"1631.4"	"1938.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y450"	"HBS1-like protein OS=Homo sapiens OX=9606 GN=HBS1L PE=1 SV=1"	"0.000"	""	"11"	"6"	"13"	"6"	"684"	"75.4"	"6.61"	"2463.52"	"24.86"	"5"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144, Pf08938"	"10767"	"ENSG00000112339"	"HBS1L"	"B7Z365; hsa:10767; Q4VX89; Q4VX90; Q5T7G3; Q8NDW9; Q9UPW3; Q9Y450"	""	"mRNA decay by 3' to 5' exoribonuclease"	"1"	"0"	"327.4"	"295.7"	"392.8"	"433.9"	"315.2"	"351.3"	"1078.8"	"1253.7"	"1478.4"	"1264.9"	"1112.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53621"	"Coatomer subunit alpha OS=Homo sapiens OX=9606 GN=COPA PE=1 SV=2"	"0.000"	""	"7"	"7"	"15"	"7"	"1224"	"138.3"	"7.66"	"2292.98"	"24.76"	"5"	"6"	"transport;signal transduction"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf04053, Pf06957, Pf12894"	"1314"	"ENSG00000122218"	"COPA"	"hsa:1314; P53621; Q5T201; Q8IXZ9"	""	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"2"	"0"	"521.1"	"490.6"	"544.4"	"615.5"	"480.9"	"417.0"	"714.3"	"772.6"	"888.1"	"2265.2"	"3506.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z6Z7"	"E3 ubiquitin-protein ligase HUWE1 OS=Homo sapiens OX=9606 GN=HUWE1 PE=1 SV=3"	"0.000"	""	"2"	"6"	"8"	"6"	"4374"	"481.6"	"5.22"	"1172.12"	"24.76"	"3"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00627, Pf00632, Pf02825, Pf06012, Pf06025, Pf14377"	"10075"	"ENSG00000086758"	"HUWE1"	"hsa:10075; O15029; Q4G2Z2; Q5H961; Q6P4D0; Q7Z6Z7; Q8NG67; Q9BUI0; Q9HCJ4; Q9NSL6; Q9P0A9"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	"2"	"0"	"94.6"	"81.0"	"111.8"	"120.9"	"111.1"	"109.0"	"149.5"	"165.0"	"206.7"	"426.0"	"622.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13283"	"Ras GTPase-activating protein-binding protein 1 OS=Homo sapiens OX=9606 GN=G3BP1 PE=1 SV=1"	"0.000"	""	"19"	"6"	"11"	"6"	"466"	"52.1"	"5.52"	"1672.11"	"24.67"	"5"	"6"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf02136"	"10146"	"ENSG00000145907"	"G3BP1"	"hsa:10146; Q13283; Q5HYE9"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"269.6"	"268.4"	"355.0"	"424.3"	"302.6"	"303.5"	"482.5"	"524.8"	"615.6"	"1215.8"	"1761.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L576"	"Cytoplasmic FMR1-interacting protein 1 OS=Homo sapiens OX=9606 GN=CYFIP1 PE=1 SV=1"	"0.000"	""	"6"	"7"	"16"	"1"	"1253"	"145.1"	"6.90"	"2837.41"	"24.59"	"7"	"7"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf05994, Pf07159"	"23191"	"ENSG00000273749; ENSG00000288461"	"CYFIP1"	"A8K6D9; hsa:23191; Q14467; Q5IED0; Q6ZSX1; Q7L576; Q9BSD9; Q9BVC7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; G13 signaling pathway"	"Neutrophil degranulation; VEGFA-VEGFR2 Pathway; RAC3 GTPase cycle; RAC1 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle"	"15"	"0"	"27.5"	"20.0"	"30.8"	"41.8"	"28.1"	"24.7"	"62.3"	"68.1"	"101.2"	"226.3"	"298.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07196"	"Neurofilament light polypeptide OS=Homo sapiens OX=9606 GN=NEFL PE=1 SV=3"	"0.000"	""	"12"	"6"	"15"	"5"	"543"	"61.5"	"4.65"	"3435.86"	"24.46"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038, Pf04732"	"4747"	"ENSG00000277586"	"NEFL"	"B9ZVN2; hsa:4747; P07196; Q16154; Q8IU72"	"Amyotrophic lateral sclerosis (ALS); Physico-chemical features and toxicity-associated pathways; NO/cGMP/PKG mediated neuroprotection; Ciliary landscape; Intracellular trafficking proteins involved in CMT neuropathy; CCL18 signaling pathway"	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation"	"12"	"0"	"639.4"	"607.0"	"680.0"	"727.1"	"528.8"	"599.7"	"780.9"	"800.8"	"911.4"	"1730.5"	"2286.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAQ2"	"SWI/SNF complex subunit SMARCC2 OS=Homo sapiens OX=9606 GN=SMARCC2 PE=1 SV=1"	"0.000"	""	"7"	"6"	"12"	"5"	"1214"	"132.8"	"5.69"	"2155.54"	"24.45"	"5"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf04433, Pf16495, Pf16496, Pf16498"	"6601"	"ENSG00000139613"	"SMARCC2"	"F8VTJ5; hsa:6601; Q59GV3; Q8TAQ2; Q92923; Q96E12; Q96GY4"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome; 10q11.21q11.23 copy number variation syndrome"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"7"	"0"	"358.1"	"300.9"	"326.9"	"400.4"	"322.5"	"339.6"	"490.0"	"538.4"	"689.6"	"1545.9"	"2119.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75390"	"Citrate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=CS PE=1 SV=2"	"0.000"	""	"15"	"7"	"14"	"7"	"466"	"51.7"	"8.32"	"2664.92"	"24.43"	"7"	"7"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00285"	"1431"	"ENSG00000062485"	"CS"	"hsa:1431; O75390; Q71UT9; Q7KZH0; Q96FZ8; Q9BWN8"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"Mitochondrial protein import; Citric acid cycle (TCA cycle)"	"6"	"0"	"991.8"	"962.4"	"995.2"	"1160.5"	"817.7"	"885.1"	"1218.6"	"1208.4"	"1299.3"	"2362.7"	"3755.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUU7"	"ATP-dependent RNA helicase DDX19A OS=Homo sapiens OX=9606 GN=DDX19A PE=1 SV=1"	"0.000"	""	"16"	"7"	"12"	"3"	"478"	"53.9"	"6.58"	"1790.18"	"24.43"	"5"	"7"	"other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"55308"	"ENSG00000168872"	"DDX19A"	"B2RPL0; B4DRZ7; hsa:55308; Q53FM0; Q9NUU7"	""	""	"0"	"4"	"253.9"	"191.0"	"358.2"	"413.6"	"269.6"	"282.7"	"463.5"	"472.7"	"654.7"	"1680.6"	"2750.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHD8"	"Septin-9 OS=Homo sapiens OX=9606 GN=SEPTIN9 PE=1 SV=2"	"0.000"	""	"13"	"6"	"11"	"6"	"586"	"65.4"	"8.97"	"2023.58"	"24.37"	"5"	"6"	"cell cycle OR cell proliferation;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"10801"	"ENSG00000184640"	"SEPTIN9"	"A8K2V3; B3KPM0; B4DTL9; B4E0N2; B4E274; B7Z654; hsa:10801; Q96QF3; Q96QF4; Q96QF5; Q9HA04; Q9UG40; Q9UHD8; Q9Y5W4"	""	""	"0"	"0"	"427.7"	"388.5"	"496.7"	"527.0"	"423.5"	"446.8"	"685.5"	"714.5"	"1007.3"	"2014.6"	"2639.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14776"	"Transcription elongation regulator 1 OS=Homo sapiens OX=9606 GN=TCERG1 PE=1 SV=2"	"0.000"	""	"7"	"7"	"13"	"7"	"1098"	"123.8"	"8.65"	"2314.29"	"24.36"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00397, Pf01846"	"10915"	"ENSG00000113649"	"TCERG1"	"hsa:10915; O14776; Q2NKN2; Q59EA1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"518.4"	"554.4"	"521.0"	"655.1"	"464.9"	"506.7"	"778.5"	"822.5"	"1029.6"	"1981.2"	"2291.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51659"	"Peroxisomal multifunctional enzyme type 2 OS=Homo sapiens OX=9606 GN=HSD17B4 PE=1 SV=3"	"0.000"	""	"13"	"8"	"15"	"8"	"736"	"79.6"	"8.84"	"2960.22"	"24.34"	"8"	"7"	"other metabolic processes;developmental processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf01575, Pf02036"	"3295"	"ENSG00000133835"	"HSD17B4"	"B4DNV1; B4DVS5; E9PB82; F5HE57; hsa:3295; P51659"	"Androgen receptor network in prostate cancer; Steroid biosynthesis; Disorders of bile acid synthesis and biliary transport; Primary ovarian insufficiency"	"TYSND1 cleaves peroxisomal proteins; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"10"	"0"	"325.8"	"271.5"	"367.9"	"498.6"	"276.4"	"282.7"	"640.7"	"721.7"	"1012.3"	"2828.6"	"4155.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y490"	"Talin-1 OS=Homo sapiens OX=9606 GN=TLN1 PE=1 SV=3"	"0.000"	""	"4"	"9"	"13"	"9"	"2541"	"269.6"	"6.07"	"1993.33"	"24.30"	"6"	"7"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00373, Pf01608, Pf08913, Pf09141, Pf16511"	"7094"	"ENSG00000137076"	"TLN1"	"A6NMY0; hsa:7094; Q86YD0; Q9NZQ2; Q9UHH8; Q9UPX3; Q9Y490"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; TROP2 regulatory signaling"	"Platelet degranulation ; Signaling by BRAF and RAF1 fusions; XBP1(S) activates chaperone genes; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins"	"18"	"0"	"405.0"	"385.4"	"439.8"	"493.9"	"379.2"	"396.3"	"645.7"	"691.4"	"1009.3"	"1858.7"	"3208.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26599"	"Polypyrimidine tract-binding protein 1 OS=Homo sapiens OX=9606 GN=PTBP1 PE=1 SV=1"	"0.000"	""	"14"	"6"	"19"	"5"	"531"	"57.2"	"9.17"	"4149.82"	"24.27"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"749887"	"ENSPPYG00000009289; ENSPTRG00000010165"	"PTBP1"	"A0A2J8IKP3; A0A2J8RA51; A0A6D2WFY9; A0A8I5YPF9; K7AXA8"	""	""	"0"	"3"	"938.0"	"1232.8"	"1151.4"	"1434.6"	"906.1"	"933.4"	"1551.0"	"1589.6"	"1979.6"	"4640.6"	"6388.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P67870"	"Casein kinase II subunit beta OS=Homo sapiens OX=9606 GN=CSNK2B PE=1 SV=1"	"0.000"	""	"27"	"4"	"10"	"4"	"215"	"24.9"	"5.55"	"2280.55"	"24.13"	"4"	"4"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf01214"	"1460"	"ENSG00000204435; ENSG00000206406; ENSG00000224398; ENSG00000224774; ENSG00000228875; ENSG00000230700; ENSG00000232960"	"CSNK2B"	"B0UXA9; hsa:1460; P07312; P13862; P67870; Q4VX47"	"Alzheimer's disease and miRNA effects; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Neutrophil degranulation; Condensation of Prometaphase Chromosomes; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Synthesis of PC"	"19"	"0"	"266.0"	"236.8"	"246.6"	"275.2"	"232.4"	"158.1"	"358.3"	"410.8"	"477.5"	"1408.6"	"2811.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15126"	"Phosphomevalonate kinase OS=Homo sapiens OX=9606 GN=PMVK PE=1 SV=3"	"0.000"	""	"42"	"7"	"16"	"7"	"192"	"22.0"	"5.73"	"3051.73"	"24.13"	"6"	"6"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"kinase activity;other molecular function"	"Pf04275"	"10654"	"ENSG00000163344"	"PMVK"	"hsa:10654; Q15126; Q5TZW9"	"Cholesterol biosynthesis pathway; Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Activation of gene expression by SREBF (SREBP); Cholesterol biosynthesis"	"8"	"0"	"118.8"	"99.2"	"167.2"	"195.2"	"112.6"	"165.0"	"733.4"	"873.4"	"1382.3"	"4075.7"	"5950.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3A5"	"Ribosome maturation protein SBDS OS=Homo sapiens OX=9606 GN=SBDS PE=1 SV=4"	"0.000"	""	"44"	"7"	"12"	"7"	"250"	"28.7"	"8.75"	"3419.15"	"24.02"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity"	"Pf01172, Pf09377, Pf20268"	"51119"	"ENSG00000126524"	"SBDS"	"A8K0P4; hsa:51119; Q96FX0; Q9NV53; Q9Y3A5"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"493.9"	"399.0"	"491.5"	"658.4"	"454.0"	"501.9"	"1067.6"	"1191.8"	"1904.4"	"3299.8"	"3611.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49790"	"Nuclear pore complex protein Nup153 OS=Homo sapiens OX=9606 GN=NUP153 PE=1 SV=2"	"0.000"	""	"7"	"7"	"12"	"7"	"1475"	"153.8"	"8.73"	"2634.61"	"24.00"	"6"	"6"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf08604, Pf10599"	"9972"	"ENSG00000124789"	"NUP153"	"B4DIK2; E7EPX5; F6QR24; hsa:9972; P49790; Q4LE47; Q5T9I7; Q7Z743"	""	"Nuclear import of Rev protein; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; SUMOylation of DNA replication proteins; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"542.8"	"434.6"	"621.3"	"770.3"	"491.6"	"465.0"	"778.0"	"776.6"	"902.8"	"1583.6"	"2164.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78332"	"RNA-binding protein 6 OS=Homo sapiens OX=9606 GN=RBM6 PE=1 SV=5"	"0.000"	""	"6"	"6"	"13"	"6"	"1123"	"128.6"	"6.32"	"2439.33"	"23.91"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf17780"	"10180"	"ENSG00000004534"	"RBM6"	"B4E0G6; hsa:10180; O60549; O75524; P78332; Q86SS3"	""	""	"0"	"0"	"702.5"	"597.0"	"728.7"	"869.5"	"636.0"	"654.4"	"844.0"	"917.1"	"1047.6"	"1624.1"	"1972.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63208"	"S-phase kinase-associated protein 1 OS=Homo sapiens OX=9606 GN=SKP1 PE=1 SV=2"	"0.000"	""	"49"	"5"	"8"	"5"	"163"	"18.6"	"4.54"	"1802.34"	"23.73"	"3"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf01466, Pf03931"	"6500"	"ENSG00000113558"	"SKP1"	"D3DQ97; D3DQ98; hsa:6500; P34991; P63208; Q8TAY2"	"Cell cycle; TNF-alpha signaling pathway; Breast cancer pathway; Small cell lung cancer; Notch signaling pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; Orc1 removal from chromatin; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Neddylation; SCF(Skp2)-mediated degradation of p27/p21; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Circadian Clock; Cyclin D associated events in G1; Regulation of BACH1 activity; MAP3K8 (TPL2)-dependent MAPK1/3 activation; NOTCH1 Intracellular Domain Regulates Transcription; Prolactin receptor signaling; Iron uptake and transport; Nuclear events stimulated by ALK signaling in cancer; Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling"	"38"	"0"	"327.8"	"213.4"	"418.4"	"568.9"	"303.7"	"323.2"	"578.2"	"584.6"	"781.9"	"1743.3"	"2563.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95757"	"Heat shock 70 kDa protein 4L OS=Homo sapiens OX=9606 GN=HSPA4L PE=1 SV=3"	"0.000"	""	"8"	"5"	"12"	"4"	"839"	"94.5"	"5.88"	"2436.18"	"23.73"	"5"	"5"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00012"	"22824"	"ENSG00000164070"	"HSPA4L"	"A2ICT2; hsa:22824; O95757; Q4W5M5; Q8IWA2"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"223.3"	"194.9"	"238.3"	"305.6"	"246.5"	"229.0"	"334.8"	"366.1"	"443.7"	"959.2"	"1424.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12800"	"Alpha-globin transcription factor CP2 OS=Homo sapiens OX=9606 GN=TFCP2 PE=1 SV=2"	"0.000"	""	"12"	"5"	"12"	"4"	"502"	"57.2"	"5.80"	"2399.19"	"23.67"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7024"	"ENSG00000135457"	"TFCP2"	"A8K5E9; hsa:7024; Q12800; Q12801; Q9UD75; Q9UD77"	"VEGFA-VEGFR2 signaling"	""	"1"	"1"	"210.3"	"192.0"	"261.6"	"298.8"	"209.3"	"214.8"	"692.8"	"729.4"	"1272.5"	"2869.2"	"2951.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14314"	"Glucosidase 2 subunit beta OS=Homo sapiens OX=9606 GN=PRKCSH PE=1 SV=2"	"0.000"	""	"14"	"7"	"11"	"7"	"528"	"59.4"	"4.41"	"1970.61"	"23.65"	"5"	"6"	"protein metabolism;other metabolic processes;developmental processes;signal transduction"	"ER/Golgi;other cell component"	"other molecular function"	"Pf12999, Pf13015, Pf13202"	"5589"	"ENSG00000130175"	"PRKCSH"	"A8K318; hsa:5589; P14314; Q96BU9; Q96D06; Q9P0W9"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Advanced glycosylation endproduct receptor signaling; Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"7"	"0"	"984.6"	"829.9"	"1000.3"	"1097.5"	"905.9"	"890.8"	"1015.7"	"1018.7"	"1014.1"	"1186.5"	"1400.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49915"	"GMP synthase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=GMPS PE=1 SV=1"	"0.000"	""	"11"	"4"	"9"	"4"	"693"	"76.7"	"6.87"	"2128.39"	"23.56"	"3"	"4"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00117, Pf00958, Pf02540"	"8833"	"ENSG00000163655"	"GMPS"	"A8K639; B4DXV7; F8W720; hsa:8833; P49915"	""	"Purine ribonucleoside monophosphate biosynthesis; Azathioprine ADME"	"2"	"0"	"55.7"	"29.3"	"73.7"	"90.4"	"51.6"	"49.2"	"117.3"	"114.1"	"187.8"	"625.4"	"1402.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16630"	"Cleavage and polyadenylation specificity factor subunit 6 OS=Homo sapiens OX=9606 GN=CPSF6 PE=1 SV=2"	"0.000"	""	"17"	"8"	"15"	"8"	"551"	"59.2"	"7.15"	"2707.46"	"23.54"	"7"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00076"	"11052"	"ENSG00000111605"	"CPSF6"	"A8K7K9; hsa:11052; Q16630; Q53ES1; Q9BSJ7; Q9BW18"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"2"	"0"	"287.2"	"291.0"	"328.8"	"390.5"	"284.1"	"262.1"	"509.5"	"508.7"	"717.3"	"2146.0"	"3616.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52209"	"6-phosphogluconate dehydrogenase, decarboxylating OS=Homo sapiens OX=9606 GN=PGD PE=1 SV=3"	"0.000"	""	"17"	"6"	"10"	"6"	"483"	"53.1"	"7.23"	"1626.24"	"23.51"	"4"	"6"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00393, Pf03446"	"5226"	"ENSG00000142657"	"PGD"	"A8K2Y9; B4DQJ8; hsa:5226; P52209; Q9BWD8"	"Pentose phosphate metabolism; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; Metabolic reprogramming in colon cancer"	"NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"7"	"0"	"182.0"	"134.8"	"192.1"	"246.2"	"180.8"	"151.1"	"342.8"	"370.1"	"561.2"	"2279.1"	"4177.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60660"	"Myosin light polypeptide 6 OS=Homo sapiens OX=9606 GN=MYL6 PE=1 SV=2"	"0.000"	""	"41"	"5"	"12"	"5"	"151"	"16.9"	"4.65"	"2468.44"	"23.38"	"5"	"5"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	""	"4637"	"ENSG00000092841"	"MYL6"	"hsa:4637; P16475; P24572; P24573; P60660; Q12790; Q561V9; Q6IAZ0; Q6IPY5"	"Ciliary landscape"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"265.2"	"247.7"	"313.1"	"380.1"	"253.3"	"241.9"	"501.4"	"533.0"	"789.7"	"2467.5"	"4082.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SY0"	"Integrator complex subunit 14 OS=Homo sapiens OX=9606 GN=INTS14 PE=1 SV=2"	"0.000"	""	"14"	"5"	"12"	"5"	"518"	"57.4"	"5.12"	"2395.07"	"23.38"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf13519, Pf19435, Pf20504"	"81556"	"ENSG00000138614"	"INTS14"	"B4DDI6; B4DVD5; hsa:81556; Q49AH8; Q96HX5; Q96SY0; Q9H0S5"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"69.0"	"53.2"	"85.1"	"102.0"	"71.3"	"75.3"	"155.3"	"159.6"	"251.7"	"1035.2"	"1858.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50395"	"Rab GDP dissociation inhibitor beta OS=Homo sapiens OX=9606 GN=GDI2 PE=1 SV=2"	"0.000"	""	"13"	"5"	"8"	"5"	"445"	"50.6"	"6.47"	"1164.67"	"23.34"	"1"	"5"	"transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00996"	"2665"	"ENSG00000057608"	"GDI2"	"hsa:2665; O43928; P50395; Q5SX88; Q9UQM6"	""	"Neutrophil degranulation; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"72.0"	"70.3"	"107.7"	"158.0"	"87.9"	"72.9"	"172.3"	"176.9"	"297.7"	"1125.0"	"3098.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60814"	"Histone H2B type 1-K OS=Homo sapiens OX=9606 GN=H2BC12 PE=1 SV=3"	"0.000"	""	"42"	"6"	"14"	"2"	"126"	"13.9"	"10.32"	"2833.07"	"23.33"	"5"	"5"	"stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"85236"	"ENSG00000197903"	"H2BC12"	"A8K7P7; hsa:85236; O60814; Q2VPI7"	""	"Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of the beta-catenin:TCF transactivating complex; E3 ubiquitin ligases ubiquitinate target proteins; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; HCMV Early Events; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"5"	"743.9"	"1074.9"	"797.9"	"1055.3"	"599.8"	"687.9"	"1065.1"	"1083.1"	"1359.6"	"2716.6"	"3408.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U42"	"Polyadenylate-binding protein 2 OS=Homo sapiens OX=9606 GN=PABPN1 PE=1 SV=3"	"0.000"	""	"22"	"6"	"11"	"6"	"306"	"32.7"	"5.06"	"1727.23"	"23.33"	"5"	"6"	"RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"8106"	"ENSG00000100836"	"PABPN1"	"D3DS49; hsa:8106; O43484; Q86U42"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"6"	"0"	"843.2"	"773.2"	"1011.1"	"1275.2"	"859.9"	"811.7"	"1192.4"	"1186.6"	"1291.9"	"2219.4"	"3607.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0VDF9"	"Heat shock 70 kDa protein 14 OS=Homo sapiens OX=9606 GN=HSPA14 PE=1 SV=1"	"0.000"	""	"12"	"5"	"12"	"5"	"509"	"54.8"	"5.59"	"2311.01"	"23.31"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00012"	"51182"	"ENSG00000187522"	"HSPA14"	"A8K8F8; B0YIY9; hsa:51182; Q0VDF9; Q9P0X2; Q9UI07"	"Parkin-ubiquitin proteasomal system pathway"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"271.6"	"193.5"	"257.7"	"312.5"	"203.0"	"227.2"	"475.1"	"493.8"	"688.4"	"1609.7"	"2037.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62495"	"Eukaryotic peptide chain release factor subunit 1 OS=Homo sapiens OX=9606 GN=ETF1 PE=1 SV=3"	"0.000"	""	"22"	"8"	"14"	"8"	"437"	"49.0"	"5.71"	"2671.99"	"23.31"	"7"	"7"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf03463, Pf03464, Pf03465"	"2107"	"ENSG00000120705"	"ETF1"	"B2R6B4; D3DQC1; hsa:2107; P46055; P62495; Q5M7Z7; Q96CG1"	"Translation factors"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"5"	"0"	"322.1"	"296.9"	"346.7"	"482.5"	"342.8"	"325.7"	"801.1"	"845.1"	"1409.8"	"3060.0"	"2990.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L5N1"	"COP9 signalosome complex subunit 6 OS=Homo sapiens OX=9606 GN=COPS6 PE=1 SV=1"	"0.000"	""	"24"	"7"	"10"	"7"	"327"	"36.1"	"5.73"	"1608.06"	"23.31"	"4"	"6"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01398, Pf13012"	"10980"	"ENSG00000168090"	"COPS6"	"A4D2A3; hsa:10980; O15387; Q7L5N1"	"Nucleotide-binding oligomerization domain (NOD) pathway; Ciliary landscape"	"Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis"	"6"	"0"	"149.3"	"131.8"	"189.2"	"232.2"	"192.8"	"186.1"	"563.1"	"632.2"	"932.8"	"4318.5"	"7236.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14654"	"Insulin receptor substrate 4 OS=Homo sapiens OX=9606 GN=IRS4 PE=1 SV=1"	"0.000"	""	"5"	"7"	"10"	"7"	"1257"	"133.7"	"8.44"	"986.96"	"23.29"	"3"	"7"	"signal transduction"	"plasma membrane;other membranes;cytosol"	"signal transduction activity or receptor binding;other molecular function"	"Pf02174"	"8471"	"ENSG00000133124"	"IRS4"	"hsa:8471; O14654"	"Alzheimer's disease and miRNA effects; Adipogenesis; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; Insulin signaling; Alzheimer's disease"	"IRS-related events triggered by IGF1R"	"8"	"0"	"598.2"	"602.3"	"614.0"	"736.6"	"534.6"	"493.5"	"875.0"	"960.8"	"1201.5"	"2528.2"	"3042.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14247"	"Src substrate cortactin OS=Homo sapiens OX=9606 GN=CTTN PE=1 SV=2"	"0.000"	""	"12"	"5"	"9"	"5"	"550"	"61.5"	"5.40"	"1623.42"	"23.26"	"2"	"5"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf02218, Pf14604"	"2017"	"ENSG00000085733; ENSG00000288401"	"CTTN"	"hsa:2017; Q14247; Q8N707; Q96H99"	"Pathogenic Escherichia coli infection; Hepatitis C and hepatocellular carcinoma"	"RHO GTPases activate PAKs; Clathrin-mediated endocytosis"	"4"	"0"	"243.7"	"228.1"	"270.9"	"419.6"	"245.3"	"241.4"	"483.4"	"541.8"	"803.8"	"2884.1"	"4935.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PD62"	"RNA polymerase-associated protein CTR9 homolog OS=Homo sapiens OX=9606 GN=CTR9 PE=1 SV=1"	"0.000"	""	"6"	"6"	"10"	"6"	"1173"	"133.4"	"6.77"	"1679.49"	"23.18"	"5"	"5"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13181"	"9646"	"ENSG00000198730"	"CTR9"	"D3DQV8; hsa:9646; Q15015; Q6PD62"	"Endoderm differentiation"	"E3 ubiquitin ligases ubiquitinate target proteins; Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events"	"5"	"0"	"308.9"	"322.1"	"324.2"	"418.3"	"329.7"	"312.1"	"454.1"	"494.3"	"621.0"	"1321.1"	"1660.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15021"	"Condensin complex subunit 1 OS=Homo sapiens OX=9606 GN=NCAPD2 PE=1 SV=3"	"0.000"	""	"5"	"5"	"11"	"5"	"1401"	"157.1"	"6.61"	"1763.23"	"23.14"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12717, Pf12922"	"9918"	"ENSG00000010292"	"NCAPD2"	"D3DUR4; hsa:9918; Q15021; Q8N6U3"	""	"Condensation of Prometaphase Chromosomes"	"1"	"0"	"83.5"	"82.5"	"103.8"	"129.7"	"83.7"	"80.7"	"173.0"	"199.3"	"295.4"	"926.4"	"1400.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00422"	"Histone deacetylase complex subunit SAP18 OS=Homo sapiens OX=9606 GN=SAP18 PE=1 SV=1"	"0.000"	""	"54"	"9"	"18"	"9"	"153"	"17.6"	"9.35"	"4057.86"	"23.13"	"8"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06487"	"10284"	"ENSG00000150459"	"SAP18"	"B2R494; hsa:10284; O00422; Q2TTR4; Q6IAW9; Q8N606; Q9UF14; X6RAL5"	"Hedgehog signaling pathway"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; mRNA Splicing - Major Pathway"	"5"	"0"	"1644.2"	"1375.2"	"1692.3"	"1886.5"	"1368.2"	"1430.1"	"1971.0"	"1912.2"	"2035.1"	"2886.9"	"4083.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00535"	"Cyclin-dependent-like kinase 5 OS=Homo sapiens OX=9606 GN=CDK5 PE=1 SV=3"	"0.000"	""	"25"	"6"	"11"	"6"	"292"	"33.3"	"7.66"	"1426.88"	"23.08"	"4"	"6"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1020"	"ENSG00000164885"	"CDK5"	"A1XKG3; hsa:1020; Q00535"	"miRNA regulation of DNA damage response; Nicotine effect on dopaminergic neurons; Alzheimer's disease and miRNA effects; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling in development and disease ; Alzheimer's disease; Neurogenesis regulation in the olfactory epithelium; DNA damage response"	"DARPP-32 events; NPAS4 regulates expression of target genes; NGF-stimulated transcription; Regulation of TP53 Activity through Phosphorylation; Factors involved in megakaryocyte development and platelet production; CRMPs in Sema3A signaling; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Activated NTRK2 signals through CDK5"	"16"	"0"	"133.2"	"109.6"	"153.6"	"171.3"	"135.8"	"248.0"	"814.2"	"894.8"	"1202.5"	"3302.8"	"5302.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DP25"	"Calmodulin-3 OS=Homo sapiens OX=9606 GN=CALM3 PE=1 SV=1"	"0.000"	""	"38"	"6"	"12"	"6"	"149"	"16.8"	"4.22"	"2534.92"	"23.06"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf13499"	"801; 805; 808"	"ENSG00000160014"	"CALM3"	"hsa:801; hsa:805; hsa:808; P02593; P0DP25; P62158; P70667; P99014; Q13942; Q53S29; Q61379; Q61380; Q96HK3"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; Ras signaling; Melanoma; Endochondral ossification; Endochondral ossification with skeletal dysplasias; CAMKK2 pathway; Glycogen synthesis and degradation; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; G13 signaling pathway; Calcium regulation in cardiac cells"	""	"17"	"0"	"482.2"	"411.1"	"528.4"	"560.1"	"411.2"	"468.3"	"788.2"	"879.1"	"1130.4"	"1985.3"	"2409.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SW79"	"Centrosomal protein of 170 kDa OS=Homo sapiens OX=9606 GN=CEP170 PE=1 SV=1"	"0.000"	""	"5"	"6"	"13"	"5"	"1584"	"175.2"	"7.11"	"2768.74"	"23.02"	"6"	"5"	""	"cytosol;cytoskeleton;other cell component"	""	"Pf00498, Pf15308"	"9859"	"ENSG00000143702; ENSG00000276725"	"CEP170"	"hsa:9859; O75058; Q5SW77; Q5SW78; Q5SW79; Q7LGA9; Q86W31; Q9UQ08; Q9UQ09"	"Ciliary landscape"	""	"1"	"1"	"448.1"	"408.0"	"507.1"	"621.9"	"464.8"	"474.2"	"656.6"	"660.9"	"797.1"	"1446.7"	"1874.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FV9"	"THO complex subunit 1 OS=Homo sapiens OX=9606 GN=THOC1 PE=1 SV=1"	"0.000"	""	"12"	"6"	"11"	"6"	"657"	"75.6"	"4.98"	"2123.20"	"23.02"	"5"	"5"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00531, Pf11957"	"9984"	"ENSG00000079134"	"THOC1"	"B2RBP6; hsa:9984; Q15219; Q64I72; Q64I73; Q96FV9"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"398.7"	"419.1"	"461.2"	"552.4"	"412.0"	"366.4"	"598.1"	"646.3"	"712.2"	"1443.4"	"2103.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06899"	"Histone H2B type 1-J OS=Homo sapiens OX=9606 GN=H2BC11 PE=1 SV=3"	"0.000"	""	"42"	"6"	"14"	"2"	"126"	"13.9"	"10.32"	"2875.53"	"22.98"	"5"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"8970"	"ENSG00000124635"	"H2BC11"	"B2R4J4; hsa:8970; O60816; P06899"	""	"E3 ubiquitin ligases ubiquitinate target proteins; Deposition of new CENPA-containing nucleosomes at the centromere; Amyloid fiber formation; Meiotic synapsis; HCMV Late Events; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; HCMV Early Events; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Formation of the beta-catenin:TCF transactivating complex; Oxidative Stress Induced Senescence; HDACs deacetylate histones; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; Senescence-Associated Secretory Phenotype (SASP); RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; HATs acetylate histones; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"43"	"0"	"60.4"	"107.7"	"30.7"	"82.1"	"47.4"	"44.8"	"120.0"	"168.3"	"209.2"	"588.1"	"696.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33176"	"Kinesin-1 heavy chain OS=Homo sapiens OX=9606 GN=KIF5B PE=1 SV=1"	"0.000"	""	"8"	"5"	"9"	"5"	"963"	"109.6"	"6.51"	"1381.36"	"22.87"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3799"	"ENSG00000170759"	"KIF5B"	"A0AVB2; hsa:3799; P33176; Q5VZ85"	"Alzheimer's disease and miRNA effects; Envelope proteins and their potential roles in EDMD physiopathology; Insulin signaling; CCL18 signaling pathway; Alzheimer's disease"	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Insulin processing; Nuclear events stimulated by ALK signaling in cancer; RHO GTPases activate KTN1"	"12"	"0"	"130.6"	"128.2"	"180.5"	"201.1"	"139.0"	"150.3"	"294.4"	"313.6"	"499.7"	"1647.1"	"2037.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95400"	"CD2 antigen cytoplasmic tail-binding protein 2 OS=Homo sapiens OX=9606 GN=CD2BP2 PE=1 SV=1"	"0.000"	""	"25"	"6"	"10"	"6"	"341"	"37.6"	"4.61"	"2127.91"	"22.86"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf02213"	"10421"	"ENSG00000169217"	"CD2BP2"	"B2RDX2; hsa:10421; O95400; Q9ULP2"	"mRNA processing; Ciliary landscape"	""	"2"	"0"	"162.2"	"157.8"	"208.1"	"248.4"	"162.1"	"169.0"	"334.4"	"301.4"	"422.9"	"1550.2"	"2537.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11177"	"Pyruvate dehydrogenase E1 component subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=PDHB PE=1 SV=3"	"0.000"	""	"16"	"5"	"12"	"5"	"359"	"39.2"	"6.65"	"2241.39"	"22.86"	"5"	"5"	"other metabolic processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf02779, Pf02780"	"5162"	"ENSG00000168291"	"PDHB"	"B2R7L0; B4DDD7; hsa:5162; P11177; Q6FH45; Q9BQ27; Q9UFK3"	"Metabolic reprogramming in colon cancer; Orexin receptor pathway"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"6"	"0"	"377.6"	"337.4"	"483.4"	"577.2"	"343.3"	"406.3"	"574.6"	"631.2"	"746.8"	"1624.0"	"2486.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52701"	"DNA mismatch repair protein Msh6 OS=Homo sapiens OX=9606 GN=MSH6 PE=1 SV=2"	"0.000"	""	"6"	"6"	"10"	"6"	"1360"	"152.7"	"6.90"	"1859.76"	"22.86"	"5"	"5"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf00855, Pf01624, Pf05188, Pf05190, Pf05192"	"2956"	"ENSG00000116062"	"MSH6"	"B4DF41; B4E3I4; F5H2F9; hsa:2956; O43706; O43917; P52701; Q8TCX4; Q9BTB5"	"Glioblastoma signaling pathways; Retinoblastoma gene in cancer; Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network; DNA mismatch repair"	"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Defective Mismatch Repair Associated With MSH2; Defective Mismatch Repair Associated With MSH6"	"8"	"0"	"267.0"	"249.0"	"306.4"	"410.5"	"255.5"	"265.2"	"504.2"	"469.6"	"688.1"	"2207.6"	"3452.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15170"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3A OS=Homo sapiens OX=9606 GN=GSPT1 PE=1 SV=1"	"0.000"	""	"17"	"7"	"11"	"4"	"499"	"55.7"	"5.62"	"2026.08"	"22.76"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf03144"	"2935"	"ENSG00000103342"	"GSPT1"	"hsa:2935; J3KQG6; P15170; Q96GF2"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"4"	"2"	"125.1"	"116.5"	"159.0"	"248.3"	"149.6"	"154.2"	"307.3"	"349.2"	"509.0"	"3190.1"	"4632.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08170"	"Serine/arginine-rich splicing factor 4 OS=Homo sapiens OX=9606 GN=SRSF4 PE=1 SV=2"	"0.000"	""	"9"	"5"	"16"	"1"	"494"	"56.6"	"11.52"	"3011.86"	"22.76"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"6429"	"ENSG00000116350"	"SRSF4"	"hsa:6429; Q08170; Q5VXP1; Q9BUA4; Q9UEB5"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript"	"6"	"0"	"162.4"	"134.1"	"181.4"	"194.9"	"148.6"	"138.5"	"184.2"	"172.1"	"185.0"	"274.6"	"503.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DJD1"	"RANBP2-like and GRIP domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RGPD2 PE=2 SV=1"	"0.000"	""	"5"	"7"	"13"	"1"	"1756"	"197.2"	"6.20"	"2249.03"	"22.69"	"6"	"7"	"transport"	"nucleus;other cell component"	""	"Pf00638, Pf01465, Pf16704"	"729857"	"ENSG00000185304"	"RGPD2"	"hsa:729857; P0C839; P0DJD1; Q68DN6; Q6V1X0"	""	""	"0"	"0"	"5.2"	"9.4"	"16.8"	"7.0"	"10.5"	"6.3"	"16.0"	"11.2"	"10.2"	"22.6"	"31.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWF3"	"RNA-binding protein 4 OS=Homo sapiens OX=9606 GN=RBM4 PE=1 SV=1"	"0.000"	""	"17"	"7"	"13"	"7"	"364"	"40.3"	"7.08"	"2695.69"	"22.68"	"7"	"6"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00098"	"5936"	"ENSG00000173933"	"RBM4"	"B3KUN0; B4E1U0; E7EQS3; hsa:5936; O02916; Q4VC48; Q6P1P2; Q8WU85; Q9BWF3"	""	"Circadian Clock"	"1"	"0"	"578.5"	"544.1"	"572.4"	"675.2"	"483.9"	"444.7"	"809.1"	"846.1"	"981.8"	"2131.9"	"2907.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60256"	"Phosphoribosyl pyrophosphate synthase-associated protein 2 OS=Homo sapiens OX=9606 GN=PRPSAP2 PE=1 SV=1"	"0.000"	""	"14"	"6"	"12"	"5"	"369"	"40.9"	"7.44"	"2244.97"	"22.61"	"5"	"5"	"other metabolic processes;developmental processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5636"	"ENSG00000141127"	"PRPSAP2"	"B4E1M8; B4E329; B7ZKZ1; E7EMY2; hsa:5636; O60256; Q6IAS2"	""	""	"0"	"1"	"286.7"	"219.5"	"329.6"	"388.5"	"265.1"	"265.1"	"849.5"	"918.1"	"1482.6"	"3884.4"	"5656.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWH9"	"SAFB-like transcription modulator OS=Homo sapiens OX=9606 GN=SLTM PE=1 SV=2"	"0.000"	""	"9"	"7"	"13"	"7"	"1034"	"117.1"	"7.87"	"2157.64"	"22.58"	"6"	"7"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf02037"	"79811"	"ENSG00000137776"	"SLTM"	"A8K5V8; B2RTX3; hsa:79811; Q2VPK7; Q52MB3; Q658J7; Q6ZNF2; Q86TK6; Q9H7C3; Q9H8U9; Q9NWH9"	""	""	"0"	"0"	"484.5"	"457.8"	"584.9"	"697.8"	"459.3"	"482.3"	"729.9"	"721.4"	"864.8"	"1871.6"	"3039.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2I0"	"Cleavage and polyadenylation specificity factor subunit 2 OS=Homo sapiens OX=9606 GN=CPSF2 PE=1 SV=2"	"0.000"	""	"11"	"7"	"12"	"7"	"782"	"88.4"	"5.11"	"2129.14"	"22.53"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07521, Pf10996, Pf13299, Pf16661"	"53981"	"ENSG00000165934"	"CPSF2"	"B3KME1; hsa:53981; Q6NSJ1; Q9H3W7; Q9P2I0"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"356.0"	"335.3"	"361.2"	"452.9"	"327.0"	"296.6"	"524.1"	"555.4"	"745.7"	"1512.2"	"2040.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0C0S8"	"Histone H2A type 1 OS=Homo sapiens OX=9606 GN=H2AC11 PE=1 SV=2"	"0.000"	""	"35"	"4"	"11"	"2"	"130"	"14.1"	"10.90"	"1952.43"	"22.51"	"3"	"4"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"8329; 8330; 8332; 8336; 8969"	"ENSG00000196747; ENSG00000196787; ENSG00000275221; ENSG00000276903; ENSG00000278677"	"H2AC11; H2AC13; H2AC15; H2AC16; H2AC17"	"hsa:8329; hsa:8330; hsa:8332; hsa:8336; hsa:8969; P02261; P0C0S8; Q2M1R2; Q76PA6"	"Pathways affected in adenoid cystic carcinoma"	"UCH proteinases; Ub-specific processing proteases; HCMV Late Events; HCMV Early Events; HDACs deacetylate histones; Metalloprotease DUBs; RMTs methylate histone arginines; HATs acetylate histones"	"9"	"2"	"608.3"	"715.1"	"782.6"	"966.8"	"565.0"	"613.7"	"922.5"	"894.3"	"1105.6"	"2066.0"	"2976.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46939"	"Utrophin OS=Homo sapiens OX=9606 GN=UTRN PE=1 SV=2"	"0.000"	""	"3"	"6"	"12"	"6"	"3433"	"394.2"	"5.33"	"2349.16"	"22.50"	"5"	"5"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00569, Pf09068, Pf09069"	"7402"	"ENSG00000152818"	"UTRN"	"hsa:7402; P46939; Q5SYY1; Q5SZ57; Q9UJ40"	"Primary focal segmental glomerulosclerosis (FSGS)"	"EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"2"	"0"	"153.8"	"155.2"	"183.0"	"228.7"	"148.4"	"153.7"	"257.1"	"253.1"	"336.6"	"664.0"	"914.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13868"	"Exosome complex component RRP4 OS=Homo sapiens OX=9606 GN=EXOSC2 PE=1 SV=2"	"0.000"	""	"17"	"4"	"12"	"4"	"293"	"32.8"	"7.50"	"2832.95"	"22.46"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14382, Pf15985"	"23404"	"ENSG00000130713"	"EXOSC2"	"A3KFL3; A3KFL4; B4DKK6; hsa:23404; Q13868; Q9NUY4"	"Ciliary landscape"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"223.5"	"220.5"	"278.3"	"338.8"	"231.7"	"212.0"	"353.8"	"398.2"	"506.9"	"1513.8"	"2512.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBS9"	"Thioredoxin domain-containing protein 5 OS=Homo sapiens OX=9606 GN=TXNDC5 PE=1 SV=2"	"0.000"	""	"17"	"7"	"14"	"7"	"432"	"47.6"	"5.97"	"1951.17"	"22.44"	"4"	"7"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00085"	"81567"	"ENSG00000239264"	"TXNDC5"	"B2RDM2; hsa:81567; Q5TCQ0; Q8NBS9; Q8ND33; Q8TCT2; Q9BVH9"	"VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Lysosome Vesicle Biogenesis"	"4"	"0"	"666.1"	"694.4"	"750.5"	"836.7"	"726.4"	"541.6"	"1039.2"	"1168.1"	"1173.5"	"2361.6"	"3639.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13148"	"TAR DNA-binding protein 43 OS=Homo sapiens OX=9606 GN=TARDBP PE=1 SV=1"	"0.000"	""	"14"	"5"	"13"	"5"	"414"	"44.7"	"6.19"	"2128.27"	"22.44"	"3"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf18694"	"23435"	"ENSG00000120948"	"TARDBP"	"A4GUK4; A4GUK5; A4GUK6; B2R629; B4DJ45; E2PU12; hsa:23435; Q13148; Q53H27; Q6FI92; Q96DJ0"	"MECP2 and associated Rett syndrome"	""	"1"	"0"	"341.8"	"327.5"	"381.5"	"480.9"	"342.1"	"316.0"	"555.9"	"564.7"	"679.9"	"1382.4"	"2150.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25787"	"Proteasome subunit alpha type-2 OS=Homo sapiens OX=9606 GN=PSMA2 PE=1 SV=2"	"0.000"	""	"22"	"4"	"9"	"4"	"234"	"25.9"	"7.43"	"1620.76"	"22.36"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5683"	"ENSG00000106588"	"PSMA2"	"hsa:5683; P25787; Q6ICS6; Q9BU45"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; Neddylation; Neutrophil degranulation; Antigen processing: Ubiquitination & Proteasome degradation; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"190.5"	"183.3"	"242.1"	"323.7"	"184.1"	"206.4"	"293.2"	"303.3"	"396.7"	"1002.0"	"2254.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62888"	"60S ribosomal protein L30 OS=Homo sapiens OX=9606 GN=RPL30 PE=1 SV=2"	"0.000"	""	"35"	"4"	"11"	"4"	"115"	"12.8"	"9.63"	"1922.48"	"22.29"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6156"	"ENSG00000156482"	"RPL30"	"B2R591; hsa:6156; P04645; P62888; Q502Z6"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"85.6"	"89.3"	"125.5"	"157.0"	"100.4"	"110.9"	"231.3"	"251.5"	"344.5"	"1146.1"	"1935.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05682"	"Caldesmon OS=Homo sapiens OX=9606 GN=CALD1 PE=1 SV=3"	"0.000"	""	"9"	"8"	"13"	"8"	"793"	"93.2"	"5.66"	"2732.24"	"22.27"	"7"	"6"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02029"	"800"	"ENSG00000122786"	"CALD1"	"A8K0X1; hsa:800; Q05682; Q13978; Q13979; Q14741; Q14742; Q9UD91"	"Myometrial relaxation and contraction pathways"	"Smooth Muscle Contraction"	"2"	"0"	"695.9"	"621.7"	"646.1"	"798.6"	"658.4"	"694.4"	"1122.8"	"1177.7"	"1724.3"	"4221.8"	"5460.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14151"	"Scaffold attachment factor B2 OS=Homo sapiens OX=9606 GN=SAFB2 PE=1 SV=1"	"0.000"	""	"7"	"7"	"14"	"3"	"953"	"107.4"	"6.16"	"2532.18"	"22.21"	"6"	"6"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf02037"	"9667"	"ENSG00000130254"	"SAFB2"	"B4DKG3; hsa:9667; Q14151; Q8TB13"	""	""	"0"	"0"	"292.7"	"257.3"	"331.3"	"416.9"	"273.2"	"293.9"	"394.4"	"406.0"	"480.2"	"1078.7"	"1824.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92621"	"Nuclear pore complex protein Nup205 OS=Homo sapiens OX=9606 GN=NUP205 PE=1 SV=3"	"0.000"	""	"4"	"7"	"12"	"7"	"2012"	"227.8"	"6.19"	"2381.19"	"22.20"	"6"	"6"	"cell organization and biogenesis;transport"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf11894"	"23165"	"ENSG00000155561"	"NUP205"	"A6H8X3; hsa:23165; Q86YC1; Q92621"	""	"Rev-mediated nuclear export of HIV RNA; Nuclear import of Rev protein; Postmitotic nuclear pore complex (NPC) reformation; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"29"	"0"	"267.3"	"231.2"	"316.8"	"374.2"	"249.2"	"220.2"	"461.8"	"480.6"	"709.2"	"1985.4"	"2833.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39019"	"40S ribosomal protein S19 OS=Homo sapiens OX=9606 GN=RPS19 PE=1 SV=2"	"0.000"	""	"37"	"6"	"12"	"6"	"145"	"16.1"	"10.32"	"2455.65"	"22.14"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01090"	"6223"	"ENSG00000105372"	"RPS19"	"hsa:6223; P39019"	"Complement system; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"949.9"	"979.3"	"1134.4"	"1363.5"	"939.7"	"881.8"	"1273.2"	"1269.5"	"1321.9"	"2117.3"	"2069.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15344"	"E3 ubiquitin-protein ligase Midline-1 OS=Homo sapiens OX=9606 GN=MID1 PE=1 SV=1"	"0.000"	""	"7"	"4"	"9"	"4"	"667"	"75.2"	"6.80"	"1565.90"	"22.13"	"3"	"4"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00041, Pf00622, Pf00643, Pf13445, Pf13765, Pf18568"	"4281"	"ENSG00000101871"	"MID1"	"B2RCG2; hsa:4281; O15344; O75361; Q9BZX5"	""	"Interferon gamma signaling"	"1"	"0"	"205.2"	"122.6"	"200.9"	"271.8"	"223.7"	"260.6"	"733.4"	"780.0"	"1161.8"	"1981.9"	"1991.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13217"	"DnaJ homolog subfamily C member 3 OS=Homo sapiens OX=9606 GN=DNAJC3 PE=1 SV=1"	"0.000"	""	"17"	"8"	"12"	"8"	"504"	"57.5"	"6.15"	"2420.54"	"22.12"	"6"	"6"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00226, Pf00515, Pf13181, Pf13432"	"5611"	"ENSG00000102580"	"DNAJC3"	"hsa:5611; Q13217; Q86WT9; Q8N4N2"	"Photodynamic therapy-induced unfolded protein response"	"Neutrophil degranulation; Viral mRNA Translation; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"6"	"0"	"399.1"	"356.0"	"412.7"	"453.7"	"415.6"	"453.8"	"948.8"	"1009.6"	"1545.1"	"4065.0"	"5235.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61160"	"Actin-related protein 2 OS=Homo sapiens OX=9606 GN=ACTR2 PE=1 SV=1"	"0.000"	""	"21"	"8"	"16"	"8"	"394"	"44.7"	"6.74"	"3131.99"	"22.08"	"8"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00022"	"10097"	"ENSG00000138071"	"ACTR2"	"B2RCP5; D6W5F4; E9PF41; hsa:10097; O15142; P61160; Q96C82"	"Physico-chemical features and toxicity-associated pathways; Embryonic stem cell pluripotency pathways"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"604.8"	"504.3"	"667.7"	"773.8"	"592.4"	"573.5"	"1383.6"	"1516.0"	"2563.6"	"4438.5"	"5188.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06454"	"Prothymosin alpha OS=Homo sapiens OX=9606 GN=PTMA PE=1 SV=2"	"0.000"	""	"14"	"2"	"10"	"2"	"111"	"12.2"	"3.78"	"2482.71"	"22.06"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf03247"	"5757"	"ENSG00000187514"	"PTMA"	"hsa:5757; P06454; Q15249; Q15592"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"744.0"	"513.7"	"682.1"	"710.3"	"637.5"	"727.5"	"754.2"	"749.7"	"712.7"	"745.6"	"771.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVP2"	"Guanine nucleotide-binding protein-like 3 OS=Homo sapiens OX=9606 GN=GNL3 PE=1 SV=2"	"0.000"	""	"16"	"7"	"12"	"7"	"549"	"62.0"	"9.16"	"2306.32"	"21.98"	"6"	"5"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf08701"	"26354"	"ENSG00000163938"	"GNL3"	"B2RDC1; hsa:26354; Q5PU80; Q96SV6; Q96SV7; Q9BVP2; Q9UJY0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"286.9"	"237.5"	"349.6"	"485.3"	"289.7"	"280.7"	"563.3"	"610.7"	"889.0"	"2228.1"	"3134.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14126"	"Desmoglein-2 OS=Homo sapiens OX=9606 GN=DSG2 PE=1 SV=2"	"0.000"	""	"8"	"7"	"12"	"7"	"1118"	"122.2"	"5.24"	"2402.15"	"21.98"	"6"	"6"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00028"	"1829"	"ENSG00000046604"	"DSG2"	"hsa:1829; Q14126; Q4KKU6"	"Arrhythmogenic right ventricular cardiomyopathy; GDNF signaling"	"Formation of the cornified envelope; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"8"	"0"	"798.5"	"672.3"	"806.3"	"981.0"	"717.6"	"722.1"	"1142.3"	"1204.2"	"1455.3"	"2999.4"	"4057.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99460"	"26S proteasome non-ATPase regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PSMD1 PE=1 SV=2"	"0.000"	""	"6"	"5"	"12"	"5"	"953"	"105.8"	"5.39"	"2285.20"	"21.93"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01851, Pf13646, Pf18004"	"5707"	"ENSG00000173692"	"PSMD1"	"B8ZZH9; hsa:5707; Q24JU0; Q53TI2; Q6GMU5; Q6P2P4; Q6PJM7; Q6PKG9; Q86VU1; Q8IV79; Q99460"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"688.1"	"531.2"	"713.5"	"806.0"	"564.9"	"615.2"	"830.1"	"837.5"	"916.5"	"1792.2"	"3927.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06330"	"Recombining binding protein suppressor of hairless OS=Homo sapiens OX=9606 GN=RBPJ PE=1 SV=3"	"0.000"	""	"15"	"4"	"7"	"4"	"500"	"55.6"	"7.18"	"743.15"	"21.93"	"2"	"4"	"cell cycle OR cell proliferation;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09270, Pf09271, Pf20144"	"3516"	"ENSG00000168214"	"RBPJ"	"B4DY22; hsa:3516; Q06330; Q5XKH9; Q6P1N3"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; PTF1A related regulatory pathway; Epithelial to mesenchymal transition in colorectal cancer; Osteoblast differentiation and related diseases; Genetic causes of porto-sinusoidal vascular disease; Notch signaling pathway"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Somitogenesis; Formation of paraxial mesoderm; Pre-NOTCH Transcription and Translation; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"20"	"0"	"72.6"	"69.2"	"89.5"	"113.5"	"80.8"	"75.1"	"262.3"	"325.9"	"639.4"	"1209.3"	"991.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00013"	"55 kDa erythrocyte membrane protein OS=Homo sapiens OX=9606 GN=MPP1 PE=1 SV=2"	"0.000"	""	"17"	"6"	"10"	"6"	"466"	"52.3"	"7.37"	"1540.74"	"21.91"	"4"	"6"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;kinase activity"	"Pf00018, Pf00595, Pf00625"	"4354"	"ENSG00000130830"	"MPP1"	"B4DZV5; G3XAI1; hsa:4354; Q00013; Q2TSB6; Q5J7V5"	"MECP2 and associated Rett syndrome"	"Sensory processing of sound by outer hair cells of the cochlea"	"2"	"0"	"149.3"	"116.2"	"152.0"	"202.0"	"164.6"	"138.4"	"353.1"	"368.3"	"629.3"	"1392.3"	"1830.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49757"	"Protein numb homolog OS=Homo sapiens OX=9606 GN=NUMB PE=1 SV=2"	"0.000"	""	"11"	"5"	"9"	"5"	"651"	"70.8"	"8.51"	"1267.82"	"21.90"	"2"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00640, Pf06311"	"8650"	"ENSG00000133961"	"NUMB"	"B1P2N5; B1P2N6; B1P2N7; B1P2N8; B1P2N9; B4E2B1; hsa:8650; P49757; Q6NUQ7; Q86SY1; Q8WW73; Q9UBG1; Q9UEQ4; Q9UKE8; Q9UKE9; Q9UKF0; Q9UQJ4"	"Notch signaling; VEGFA-VEGFR2 signaling; Head and neck squamous cell carcinoma; Neurogenesis regulation in the olfactory epithelium; TROP2 regulatory signaling; Notch signaling pathway"	"Recycling pathway of L1; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Activated NOTCH1 Transmits Signal to the Nucleus"	"10"	"0"	"159.4"	"129.0"	"179.0"	"226.9"	"144.4"	"159.6"	"420.1"	"475.6"	"629.6"	"1035.4"	"1091.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY44"	"Eukaryotic translation initiation factor 2A OS=Homo sapiens OX=9606 GN=EIF2A PE=1 SV=3"	"0.000"	""	"12"	"6"	"13"	"6"	"585"	"64.9"	"8.87"	"2429.43"	"21.89"	"6"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;translational apparatus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf08662"	"83939"	"ENSG00000144895"	"EIF2A"	"A8MPS6; B4DF96; B4DQ14; D3DNI9; hsa:83939; Q5QTR2; Q7Z4E9; Q8NFM1; Q96EW9; Q96K81; Q9BY44"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	""	"3"	"0"	"392.2"	"410.3"	"420.8"	"491.9"	"409.9"	"383.0"	"680.5"	"713.7"	"1009.0"	"2147.1"	"2688.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62269"	"40S ribosomal protein S18 OS=Homo sapiens OX=9606 GN=RPS18 PE=1 SV=3"	"0.000"	""	"34"	"7"	"16"	"7"	"152"	"17.7"	"10.99"	"3538.22"	"21.84"	"7"	"5"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00416"	"6222"	"ENSG00000096150; ENSG00000223367; ENSG00000226225; ENSG00000231500; ENSG00000235650"	"RPS18"	"hsa:6222; P25232; P62269; Q5SUJ3; Q6IPF8"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"807.6"	"801.2"	"958.4"	"1351.7"	"769.0"	"811.9"	"1341.3"	"1438.8"	"1653.1"	"3624.5"	"5652.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PKG0"	"La-related protein 1 OS=Homo sapiens OX=9606 GN=LARP1 PE=1 SV=2"	"0.000"	""	"10"	"9"	"13"	"9"	"1096"	"123.4"	"8.82"	"2469.10"	"21.81"	"7"	"6"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf05383"	"23367"	"ENSG00000155506"	"LARP1"	"hsa:23367; O94836; Q6PKG0; Q8N4M2; Q8NB73; Q9UFD7"	"Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Network map of SARS-CoV-2 signaling pathway"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"4"	"0"	"924.9"	"824.8"	"1034.4"	"1125.3"	"832.3"	"888.7"	"1225.0"	"1275.2"	"1544.2"	"2930.1"	"4158.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14910"	"Protein lin-7 homolog A OS=Homo sapiens OX=9606 GN=LIN7A PE=1 SV=2"	"0.000"	""	"25"	"7"	"13"	"3"	"233"	"26.0"	"8.72"	"2155.60"	"21.74"	"6"	"6"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00595, Pf02828"	"8825"	"ENSG00000111052"	"LIN7A"	"A4FTY3; hsa:8825; O14910; Q147W1; Q6LES3; Q7LDS4"	""	"Assembly and cell surface presentation of NMDA receptors; Neurexins and neuroligins; Dopamine Neurotransmitter Release Cycle"	"3"	"0"	"154.4"	"160.3"	"148.4"	"185.9"	"148.4"	"157.6"	"328.3"	"390.2"	"595.5"	"1802.4"	"2434.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13642"	"Four and a half LIM domains protein 1 OS=Homo sapiens OX=9606 GN=FHL1 PE=1 SV=4"	"0.000"	""	"19"	"5"	"8"	"5"	"323"	"36.2"	"8.97"	"1254.40"	"21.73"	"3"	"5"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00412"	"2273"	"ENSG00000022267"	"FHL1"	"B7Z5T4; B7Z793; hsa:2273; O95212; Q13230; Q13642; Q13645; Q5JXI7; Q5M7Y6; Q6IB30; Q9NZ40; Q9UKZ8; Q9Y630"	"Notch signaling pathway"	""	"1"	"0"	"475.5"	"444.0"	"464.3"	"572.1"	"412.1"	"327.0"	"641.4"	"659.2"	"774.7"	"1155.7"	"1186.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VM9"	"Zinc finger CCCH domain-containing protein 18 OS=Homo sapiens OX=9606 GN=ZC3H18 PE=1 SV=2"	"0.000"	""	"9"	"7"	"12"	"7"	"953"	"106.3"	"8.32"	"2030.83"	"21.72"	"6"	"5"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18044"	"124245"	"ENSG00000158545"	"ZC3H18"	"hsa:124245; Q86VM9; Q96DG4; Q96MP7"	""	""	"0"	"0"	"899.8"	"828.6"	"864.7"	"955.1"	"788.3"	"824.7"	"984.1"	"1021.5"	"1049.4"	"1641.0"	"2114.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12236"	"ADP/ATP translocase 3 OS=Homo sapiens OX=9606 GN=SLC25A6 PE=1 SV=4"	"0.000"	""	"19"	"6"	"13"	"1"	"298"	"32.8"	"9.74"	"2237.31"	"21.69"	"5"	"6"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"293"	"ENSG00000169100"	"SLC25A6"	"hsa:293; P12236; Q96C49"	"Electron transport chain: OXPHOS system in mitochondria; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane; Mitochondrial protein import; Influenza Virus Induced Apoptosis; Vpr-mediated induction of apoptosis by mitochondrial outer membrane permeabilization"	"7"	"0"	"106.8"	"99.3"	"128.8"	"161.8"	"97.5"	"100.8"	"200.2"	"208.9"	"308.2"	"599.3"	"815.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25098"	"Beta-adrenergic receptor kinase 1 OS=Homo sapiens OX=9606 GN=GRK2 PE=1 SV=2"	"0.000"	""	"10"	"5"	"7"	"5"	"689"	"79.5"	"7.28"	"936.53"	"21.67"	"3"	"4"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00615"	"156"	"ENSG00000173020"	"GRK2"	"B0ZBE1; hsa:156; P25098; Q13837; Q6GTT3"	"Chemokine signaling pathway; Hedgehog signaling pathway; Hedgehog signaling pathway"	"G alpha (q) signalling events; Activation of SMO; G alpha (s) signalling events; Cargo recognition for clathrin-mediated endocytosis; Calmodulin induced events"	"8"	"0"	"99.3"	"98.6"	"115.2"	"150.8"	"94.3"	"90.7"	"321.7"	"379.4"	"617.3"	"2471.1"	"2633.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULW0"	"Targeting protein for Xklp2 OS=Homo sapiens OX=9606 GN=TPX2 PE=1 SV=2"	"0.000"	""	"10"	"6"	"11"	"6"	"747"	"85.6"	"9.23"	"1780.64"	"21.64"	"5"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06886, Pf09041, Pf12214"	"22974"	"ENSG00000088325"	"TPX2"	"hsa:22974; Q96RR5; Q9H1R4; Q9NRA3; Q9UFN9; Q9UL00; Q9ULW0; Q9Y2M1"	"Gastric cancer network 1"	"Regulation of TP53 Activity through Phosphorylation; AURKA Activation by TPX2"	"3"	"0"	"514.3"	"457.3"	"531.8"	"615.4"	"494.2"	"479.1"	"706.6"	"700.6"	"903.6"	"1585.3"	"1940.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14554"	"Protein disulfide-isomerase A5 OS=Homo sapiens OX=9606 GN=PDIA5 PE=1 SV=1"	"0.000"	""	"13"	"6"	"11"	"6"	"519"	"59.6"	"7.91"	"2175.23"	"21.54"	"5"	"6"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00085"	"10954"	"ENSG00000065485"	"PDIA5"	"D3DN95; hsa:10954; Q14554; Q9BV43"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	"280.0"	"236.3"	"272.5"	"339.2"	"262.1"	"252.8"	"719.2"	"802.5"	"1166.0"	"1255.6"	"880.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92614"	"Unconventional myosin-XVIIIa OS=Homo sapiens OX=9606 GN=MYO18A PE=1 SV=3"	"0.000"	""	"3"	"5"	"10"	"5"	"2054"	"233.0"	"6.30"	"2520.61"	"21.52"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00063, Pf01576, Pf17820"	"399687"	"ENSG00000196535"	"MYO18A"	"hsa:399687; Q5H9U3; Q5QD01; Q5W9F9; Q5W9G1; Q8IXP8; Q92614"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; Signaling by FLT3 fusion proteins"	"3"	"0"	"211.8"	"202.7"	"232.2"	"293.0"	"202.5"	"201.1"	"290.7"	"320.9"	"358.1"	"789.9"	"978.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NC0"	"Zinc finger matrin-type protein 2 OS=Homo sapiens OX=9606 GN=ZMAT2 PE=1 SV=1"	"0.000"	""	"35"	"8"	"17"	"8"	"199"	"23.6"	"9.01"	"2661.68"	"21.50"	"6"	"7"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12171"	"153527"	"ENSG00000146007"	"ZMAT2"	"hsa:153527; Q96NC0"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"1684.6"	"1483.7"	"1992.8"	"2588.3"	"1571.8"	"1587.6"	"2393.7"	"2456.7"	"3038.0"	"4778.1"	"5361.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UE4"	"Protein LYRIC OS=Homo sapiens OX=9606 GN=MTDH PE=1 SV=2"	"0.000"	""	"15"	"6"	"10"	"6"	"582"	"63.8"	"9.32"	"2148.75"	"21.48"	"5"	"5"	"signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15686"	"92140"	"ENSG00000147649"	"MTDH"	"hsa:92140; Q05DH2; Q52QU9; Q6PK07; Q86UE4; Q8TCX3"	"Gastric cancer network 2; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; CCL18 signaling pathway"	""	"3"	"0"	"418.9"	"386.9"	"430.5"	"469.9"	"404.6"	"403.6"	"729.2"	"765.4"	"1176.8"	"2079.6"	"2142.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43490"	"Nicotinamide phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=NAMPT PE=1 SV=1"	"0.000"	""	"18"	"8"	"13"	"8"	"491"	"55.5"	"7.15"	"1859.51"	"21.42"	"6"	"7"	"cell-cell signaling;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf04095, Pf18127"	"10135"	"ENSG00000105835"	"NAMPT"	"A4D0Q9; A4D0R0; hsa:10135; P43490; Q3KQV0; Q8WW95"	"Adipogenesis; NAD metabolism, sirtuins and aging; NAD+ metabolism; NAD+ biosynthetic pathways; Caloric restriction and aging; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence"	"NPAS4 regulates expression of target genes; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nicotinamide salvaging"	"9"	"0"	"478.3"	"454.8"	"468.7"	"491.9"	"403.9"	"472.8"	"844.0"	"866.7"	"1322.7"	"2689.3"	"3440.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61289"	"Proteasome activator complex subunit 3 OS=Homo sapiens OX=9606 GN=PSME3 PE=1 SV=1"	"0.000"	""	"28"	"7"	"12"	"7"	"254"	"29.5"	"5.95"	"2014.73"	"21.42"	"5"	"6"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02251, Pf02252"	"10197"	"ENSG00000131467"	"PSME3"	"A8K9A3; hsa:10197; O35563; P61289; P97373; Q12920; Q13172; Q9BQD9"	"Proteasome degradation"	"Regulation of expression of SLITs and ROBOs; ER-Phagosome pathway; Separation of Sister Chromatids; Degradation of beta-catenin by the destruction complex; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Ubiquitin-dependent degradation of Cyclin D; Regulation of RUNX2 expression and activity; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling"	"60"	"0"	"362.5"	"288.5"	"390.1"	"567.4"	"353.7"	"364.6"	"676.7"	"694.9"	"975.8"	"2746.7"	"4271.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04637"	"Cellular tumor antigen p53 OS=Homo sapiens OX=9606 GN=TP53 PE=1 SV=4"	"0.000"	""	"17"	"7"	"14"	"7"	"393"	"43.6"	"6.79"	"2510.14"	"21.41"	"6"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00870, Pf07710, Pf08563, Pf18521"	"7157"	"ENSG00000141510"	"TP53"	"hsa:7157; P04637; Q15086; Q15087; Q15088; Q16535; Q16807; Q16808; Q16809; Q16810; Q16811; Q16848; Q2XN98; Q3LRW1; Q3LRW2; Q3LRW3; Q3LRW4; Q3LRW5; Q86UG1; Q8J016; Q99659; Q9BTM4; Q9HAQ8; Q9NP68; Q9NPJ2; Q9NZD0; Q9UBI2; Q9UQ61"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Fluoropyrimidine activity; TP53 network; Folate metabolism; Apoptosis modulation and signaling; Cell cycle; Metastatic brain tumor; Glioblastoma signaling pathways; Gastric cancer network 2; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Amyotrophic lateral sclerosis (ALS); ATM signaling pathway; Apoptosis; Mammary gland development pathway - Involution (Stage 4 of 4); Bladder cancer; Copper homeostasis; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; lncRNA-mediated mechanisms of therapeutic resistance; MAPK signaling pathway; miRNA regulation of p53 pathway in prostate cancer; Wnt signaling pathway and pluripotency; Endometrial cancer; PI3K-Akt signaling pathway; Caloric restriction and aging; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Ultraconserved region 339 modulation of tumor suppressor microRNAs in cancer; Ferroptosis; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; MicroRNA network associated with chronic lymphocytic leukemia; G1 to S cell cycle control; Measles virus infection; 22q11.2 copy number variation syndrome; Small cell lung cancer; Head and neck squamous cell carcinoma; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; Unfolded protein response; 16p11.2 proximal deletion syndrome; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; TCA cycle in senescence; Pleural mesothelioma; Lipid metabolism in senescent cells; DYRK1A involvement regarding cell proliferation in brain development; 2q37 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma; 11p11.2 copy number variation syndrome ; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; DNA damage response; DNA damage response (only ATM dependent)"	"TP53 Regulates Transcription of DNA Repair Genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Autodegradation of the E3 ubiquitin ligase COP1; Ub-specific processing proteases; The role of GTSE1 in G2/M progression after G2 checkpoint; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of Death Receptors and Ligands; Oxidative Stress Induced Senescence; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Association of TriC/CCT with target proteins during biosynthesis; Interleukin-4 and Interleukin-13 signaling; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of TP53 Activity through Methylation; G2/M DNA damage checkpoint; Regulation of NF-kappa B signaling; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors; Ovarian tumor domain proteases; Pyroptosis; SUMOylation of transcription factors; Regulation of TP53 Expression; RUNX3 regulates CDKN1A transcription; Activation of NOXA and translocation to mitochondria; Formation of Senescence-Associated Heterochromatin Foci (SAHF); PI5P Regulates TP53 Acetylation; Transcriptional  activation of  cell cycle inhibitor p21 ; Loss of function of TP53 in cancer due to loss of tetramerization ability"	"107"	"0"	"649.3"	"733.6"	"669.4"	"853.8"	"632.1"	"617.4"	"1077.0"	"1155.5"	"1414.7"	"3586.0"	"5256.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27694"	"Replication protein A 70 kDa DNA-binding subunit OS=Homo sapiens OX=9606 GN=RPA1 PE=1 SV=2"	"0.000"	""	"10"	"6"	"10"	"6"	"616"	"68.1"	"7.21"	"2251.23"	"21.34"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336, Pf04057, Pf08646, Pf16900"	"6117"	"ENSG00000132383"	"RPA1"	"A8K0Y9; hsa:6117; P27694; Q59ES9"	"Homologous recombination; Retinoblastoma gene in cancer; ATR signaling; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"SUMOylation of DNA damage response and repair proteins; PCNA-Dependent Long Patch Base Excision Repair; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; HSF1 activation; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"39"	"0"	"193.6"	"163.4"	"213.1"	"287.3"	"179.7"	"172.0"	"297.0"	"322.2"	"377.1"	"828.4"	"1493.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60828"	"Polyglutamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PQBP1 PE=1 SV=1"	"0.000"	""	"25"	"5"	"9"	"5"	"265"	"30.5"	"6.33"	"1919.52"	"21.17"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"10084"	"ENSG00000102103"	"PQBP1"	"C9JQA1; hsa:10084; O60828; Q4VY25; Q4VY26; Q4VY27; Q4VY29; Q4VY30; Q4VY34; Q4VY35; Q4VY36; Q4VY37; Q4VY38; Q9GZP2; Q9GZU4; Q9GZZ4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"576.1"	"536.9"	"554.9"	"630.8"	"481.8"	"543.6"	"848.6"	"897.5"	"1123.3"	"2405.8"	"2762.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31939"	"Bifunctional purine biosynthesis protein PURH OS=Homo sapiens OX=9606 GN=ATIC PE=1 SV=3"	"0.000"	""	"14"	"6"	"7"	"6"	"592"	"64.6"	"6.71"	"382.91"	"21.14"	"1"	"6"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf01808, Pf02142"	"471"	"ENSG00000138363"	"ATIC"	"A8K202; E9PBU3; hsa:471; P31939; Q13856; Q53S28"	"One-carbon metabolism"	"Signaling by ALK fusions and activated point mutants; Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	"120.6"	"91.6"	"153.0"	"224.2"	"124.8"	"120.5"	"244.8"	"251.1"	"375.0"	"1784.4"	"5093.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6NZY4"	"Zinc finger CCHC domain-containing protein 8 OS=Homo sapiens OX=9606 GN=ZCCHC8 PE=1 SV=2"	"0.000"	""	"8"	"4"	"10"	"4"	"707"	"78.5"	"4.87"	"2297.76"	"21.12"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf04046"	"55596"	"ENSG00000033030"	"ZCCHC8"	"hsa:55596; Q6NZY4; Q7L2P6; Q8N2K5; Q96SK7; Q9NSS2; Q9NSS3"	""	""	"0"	"0"	"307.4"	"308.4"	"337.2"	"386.1"	"268.7"	"293.3"	"423.0"	"422.8"	"498.5"	"918.8"	"1304.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15145"	"Actin-related protein 2/3 complex subunit 3 OS=Homo sapiens OX=9606 GN=ARPC3 PE=1 SV=3"	"0.000"	""	"25"	"5"	"12"	"5"	"178"	"20.5"	"8.59"	"2485.10"	"21.11"	"5"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04062"	"10094"	"ENSG00000111229"	"ARPC3"	"hsa:10094; O00554; O15145"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"320.9"	"327.4"	"357.3"	"413.6"	"323.7"	"292.7"	"818.5"	"877.8"	"1581.9"	"3105.3"	"3671.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Z4"	"Tyrosine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=YARS2 PE=1 SV=2"	"0.000"	""	"15"	"4"	"9"	"4"	"477"	"53.2"	"8.98"	"1629.42"	"21.09"	"3"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00579"	"51067"	"ENSG00000139131"	"YARS2"	"D3DUW8; hsa:51067; Q9H817; Q9Y2Z4"	"Orexin receptor pathway"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	"71.7"	"55.0"	"71.5"	"86.2"	"59.2"	"69.0"	"102.4"	"104.9"	"152.2"	"275.8"	"419.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T9A4"	"ATPase family AAA domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ATAD3B PE=1 SV=1"	"0.000"	""	"10"	"6"	"11"	"2"	"648"	"72.5"	"9.20"	"1926.91"	"21.06"	"5"	"6"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"83858"	"ENSG00000160072"	"ATAD3B"	"A8K3H1; hsa:83858; Q5T9A4; Q6ZRB5; Q9BUK4; Q9ULE7"	"1p36 copy number variation syndrome"	"Neutrophil degranulation"	"2"	"4"	"248.0"	"271.1"	"298.0"	"380.1"	"252.9"	"245.7"	"432.3"	"455.7"	"621.3"	"1351.9"	"1878.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92688"	"Acidic leucine-rich nuclear phosphoprotein 32 family member B OS=Homo sapiens OX=9606 GN=ANP32B PE=1 SV=1"	"0.000"	""	"26"	"7"	"14"	"4"	"251"	"28.8"	"4.06"	"2680.64"	"21.06"	"7"	"5"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12799"	"10541"	"ENSG00000136938"	"ANP32B"	"B2R9C7; hsa:10541; O00655; P78458; P78459; Q92688"	""	""	"0"	"0"	"332.0"	"329.7"	"461.3"	"623.7"	"344.7"	"388.3"	"561.2"	"606.7"	"754.5"	"1856.3"	"2697.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZJ0"	"Crooked neck-like protein 1 OS=Homo sapiens OX=9606 GN=CRNKL1 PE=1 SV=4"	"0.000"	""	"8"	"6"	"12"	"6"	"848"	"100.4"	"8.00"	"2743.03"	"21.06"	"6"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf02184"	"51340"	"ENSG00000101343"	"CRNKL1"	"A8K9T4; hsa:51340; Q5JY64; Q8WYI5; Q9BZI9; Q9BZJ0; Q9BZJ1; Q9BZJ2; Q9GZW7; Q9H8F8; Q9NQH5; Q9NYD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"185.1"	"180.1"	"220.1"	"292.5"	"189.3"	"193.1"	"364.7"	"394.8"	"593.7"	"1967.4"	"3318.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99873"	"Protein arginine N-methyltransferase 1 OS=Homo sapiens OX=9606 GN=PRMT1 PE=1 SV=3"	"0.000"	""	"15"	"5"	"10"	"5"	"371"	"42.4"	"5.35"	"2176.13"	"20.91"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13649"	"3276"	"ENSG00000126457"	"PRMT1"	"A0A087X1W2; B4E3C3; G5E9B6; H7C2I1; hsa:3276; Q15529; Q2VP93; Q6LEU5; Q8WUW5; Q99872; Q99873; Q99874; Q9NZ04; Q9NZ05; Q9NZ06"	"Energy metabolism; mRNA processing; Nitric oxide metabolism in cystic fibrosis; 16p11.2 distal deletion syndrome; Interferon type I signaling pathways"	"Estrogen-dependent gene expression; Extra-nuclear estrogen signaling; RMTs methylate histone arginines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Maturation of nucleoprotein"	"11"	"0"	"86.6"	"70.8"	"121.9"	"170.7"	"79.3"	"83.7"	"136.7"	"167.6"	"243.7"	"768.0"	"1747.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00425"	"Insulin-like growth factor 2 mRNA-binding protein 3 OS=Homo sapiens OX=9606 GN=IGF2BP3 PE=1 SV=2"	"0.000"	""	"10"	"5"	"13"	"4"	"579"	"63.7"	"8.87"	"2551.16"	"20.90"	"5"	"4"	"protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf00076"	"10643"	"ENSG00000136231"	"IGF2BP3"	"A0A4Z5; hsa:10643; O00425; Q63HM0; Q6MZZ2; Q86VB1"	""	"Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA"	"1"	"1"	"401.0"	"362.1"	"495.7"	"625.2"	"393.9"	"425.6"	"620.8"	"617.8"	"794.1"	"1623.3"	"2513.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14562"	"ATP-dependent RNA helicase DHX8 OS=Homo sapiens OX=9606 GN=DHX8 PE=1 SV=1"	"0.000"	""	"6"	"6"	"12"	"6"	"1220"	"139.2"	"8.32"	"2012.96"	"20.83"	"6"	"6"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00271, Pf00575, Pf04408, Pf07717"	"1659"	"ENSG00000067596"	"DHX8"	"hsa:1659; Q14562"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"122.6"	"110.8"	"151.8"	"185.1"	"127.1"	"142.3"	"237.8"	"247.7"	"321.8"	"990.9"	"1690.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUJ2"	"Heterogeneous nuclear ribonucleoprotein U-like protein 1 OS=Homo sapiens OX=9606 GN=HNRNPUL1 PE=1 SV=2"	"0.000"	""	"11"	"8"	"12"	"7"	"856"	"95.7"	"6.92"	"2129.67"	"20.81"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00622, Pf02037, Pf13671"	"11100"	"ENSG00000105323"	"HNRNPUL1"	"B3KMW7; hsa:11100; O76022; Q6ZSZ0; Q7L8P4; Q8N6Z4; Q96G37; Q9BUJ2; Q9HAL3; Q9UG75"	""	""	"0"	"0"	"581.4"	"498.4"	"624.0"	"804.3"	"546.3"	"580.1"	"862.4"	"930.5"	"1154.5"	"2101.7"	"2778.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60739"	"Eukaryotic translation initiation factor 1b OS=Homo sapiens OX=9606 GN=EIF1B PE=1 SV=2"	"0.000"	""	"29"	"4"	"8"	"2"	"113"	"12.8"	"7.37"	"2070.33"	"20.80"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10289"	"ENSG00000114784"	"EIF1B"	"hsa:10289; O60739; Q9UQF8"	""	""	"0"	"2"	"172.2"	"158.4"	"159.6"	"229.6"	"158.7"	"153.3"	"606.9"	"700.6"	"1192.4"	"2208.8"	"2110.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUQ3"	"Gamma-taxilin OS=Homo sapiens OX=9606 GN=TXLNG PE=1 SV=2"	"0.000"	""	"18"	"7"	"12"	"6"	"528"	"60.5"	"7.52"	"2664.12"	"20.73"	"7"	"5"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf09728"	"55787"	"ENSG00000086712"	"TXLNG"	"hsa:55787; Q2KQ75; Q5JNZ7; Q9NUQ3; Q9P0X1"	""	""	"0"	"0"	"159.3"	"153.3"	"171.9"	"249.7"	"169.1"	"155.5"	"364.2"	"414.9"	"618.9"	"1596.0"	"1786.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTC0"	"Death-inducer obliterator 1 OS=Homo sapiens OX=9606 GN=DIDO1 PE=1 SV=5"	"0.000"	""	"4"	"5"	"9"	"5"	"2240"	"243.7"	"7.88"	"1941.33"	"20.72"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00628, Pf07500, Pf07744"	"11083"	"ENSG00000101191"	"DIDO1"	"A8MY65; B9EH82; E1P5I1; hsa:11083; O15043; Q3ZTL7; Q3ZTL8; Q4VXS1; Q4VXS2; Q4VXV8; Q4VXV9; Q96D72; Q9BQW0; Q9BTC0; Q9BW03; Q9H4G6; Q9H4G7; Q9NTU8; Q9NUM8; Q9UFB6"	""	""	"0"	"0"	"161.2"	"126.6"	"188.1"	"208.4"	"163.0"	"166.2"	"222.8"	"219.7"	"297.8"	"495.3"	"680.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95202"	"Mitochondrial proton/calcium exchanger protein OS=Homo sapiens OX=9606 GN=LETM1 PE=1 SV=1"	"0.000"	""	"10"	"5"	"9"	"5"	"739"	"83.3"	"6.70"	"1427.02"	"20.71"	"4"	"5"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;translation activity;other molecular function"	"Pf07766"	"3954"	"ENSG00000168924"	"LETM1"	"B4DED2; hsa:3954; O95202; Q9UF65"	"4p16.3 copy number variation"	"RHOG GTPase cycle; Mitochondrial calcium ion transport"	"3"	"0"	"157.5"	"144.0"	"176.7"	"217.5"	"152.3"	"154.1"	"300.7"	"303.1"	"434.8"	"1078.4"	"1493.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2U1"	"ATP-dependent DNA/RNA helicase DHX36 OS=Homo sapiens OX=9606 GN=DHX36 PE=1 SV=2"	"0.000"	""	"7"	"5"	"9"	"4"	"1008"	"114.7"	"7.68"	"1404.47"	"20.66"	"4"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"170506"	"ENSG00000174953"	"DHX36"	"B2RB00; hsa:170506; Q70JU3; Q8IYE5; Q9H2U1; Q9P240"	"VEGFA-VEGFR2 signaling"	"DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"2"	"1"	"180.7"	"100.4"	"238.4"	"240.7"	"187.3"	"191.4"	"227.9"	"232.9"	"291.7"	"571.9"	"917.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14966"	"Zinc finger protein 638 OS=Homo sapiens OX=9606 GN=ZNF638 PE=1 SV=2"	"0.000"	""	"6"	"9"	"15"	"9"	"1978"	"220.5"	"6.38"	"2866.92"	"20.60"	"8"	"7"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf12171"	"27332"	"ENSG00000075292"	"ZNF638"	"A0A096LPH6; B5MDV1; B7ZLD1; hsa:27332; Q14966; Q53R34; Q5XJ05; Q68DP3; Q6P2H2; Q7Z3T7; Q8NF92; Q8TCA1; Q9H2G1; Q9NP37"	""	"Transcriptional regulation of white adipocyte differentiation"	"1"	"0"	"704.6"	"649.8"	"762.6"	"915.1"	"662.3"	"642.5"	"1027.2"	"1148.0"	"1526.1"	"2845.5"	"3081.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15381"	"Nuclear valosin-containing protein-like OS=Homo sapiens OX=9606 GN=NVL PE=1 SV=1"	"0.000"	""	"7"	"4"	"8"	"4"	"856"	"95.0"	"6.48"	"1324.39"	"20.59"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00004, Pf16725, Pf17862"	"4931"	"ENSG00000143748"	"NVL"	"B4DMC4; B4DP98; hsa:4931; O15381; Q96EM7"	""	""	"0"	"0"	"73.6"	"70.1"	"103.6"	"104.1"	"78.0"	"85.9"	"132.9"	"143.5"	"186.5"	"425.8"	"594.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41567"	"Eukaryotic translation initiation factor 1 OS=Homo sapiens OX=9606 GN=EIF1 PE=1 SV=1"	"0.000"	""	"25"	"3"	"8"	"1"	"113"	"12.7"	"7.44"	"2054.56"	"20.53"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf01253"	"10209"	"ENSG00000173812"	"EIF1"	"hsa:10209; P41567; Q9UNQ9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	""	"2"	"0"	"71.3"	"93.8"	"78.8"	"77.7"	"69.1"	"51.8"	"308.5"	"356.1"	"604.0"	"1218.2"	"933.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13045"	"Protein flightless-1 homolog OS=Homo sapiens OX=9606 GN=FLII PE=1 SV=2"	"0.000"	""	"5"	"5"	"9"	"5"	"1269"	"144.7"	"6.05"	"1598.00"	"20.53"	"4"	"5"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf12799, Pf13855"	"2314"	"ENSG00000177731; ENSG00000284571"	"FLII"	"B4DIL0; F5H407; hsa:2314; J3QLG3; Q13045"	"VEGFA-VEGFR2 signaling; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"2"	"0"	"159.3"	"151.9"	"190.3"	"248.2"	"174.7"	"160.2"	"349.2"	"370.6"	"595.7"	"2262.1"	"3439.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55081"	"Microfibrillar-associated protein 1 OS=Homo sapiens OX=9606 GN=MFAP1 PE=1 SV=2"	"0.000"	""	"15"	"7"	"12"	"7"	"439"	"51.9"	"4.98"	"2188.22"	"20.51"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes"	"extracellular matrix;cytoskeleton;nucleus"	""	"Pf06991"	"4236"	"ENSG00000140259"	"MFAP1"	"hsa:4236; P55081; Q86TG6"	"Canonical and non-canonical Notch signaling; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	"899.7"	"856.7"	"959.4"	"1083.1"	"795.4"	"865.2"	"1067.8"	"1050.7"	"1131.0"	"2341.6"	"3039.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48444"	"Coatomer subunit delta OS=Homo sapiens OX=9606 GN=ARCN1 PE=1 SV=1"	"0.000"	""	"15"	"6"	"11"	"6"	"511"	"57.2"	"6.21"	"1715.95"	"20.49"	"5"	"6"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi"	""	"Pf00928, Pf01217"	"372"	"ENSG00000095139"	"ARCN1"	"B4E1X2; E9PEU4; hsa:372; P48444; Q52M80"	"miR-517 relationship with ARCN1 and USP1"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"3"	"0"	"254.2"	"247.2"	"276.6"	"373.5"	"244.2"	"265.8"	"428.4"	"456.9"	"568.4"	"1951.3"	"3100.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3U4"	"Cohesin subunit SA-2 OS=Homo sapiens OX=9606 GN=STAG2 PE=1 SV=3"	"0.000"	""	"6"	"6"	"10"	"6"	"1231"	"141.2"	"5.43"	"1298.92"	"20.47"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf08514"	"10735"	"ENSG00000101972"	"STAG2"	"B1AMT5; D3DTF5; hsa:10735; O00540; Q5JTI6; Q68DE9; Q8N3U4; Q9H1N8"	"Cell cycle; Cohesin complex - Cornelia de Lange syndrome"	"Resolution of Sister Chromatid Cohesion; SUMOylation of DNA damage response and repair proteins; Separation of Sister Chromatids; Meiotic synapsis; Estrogen-dependent gene expression; Establishment of Sister Chromatid Cohesion; Cohesin Loading onto Chromatin"	"9"	"0"	"139.9"	"106.4"	"201.8"	"213.2"	"134.7"	"147.0"	"257.3"	"269.3"	"439.5"	"1460.9"	"2087.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6L8Q7"	"2',5'-phosphodiesterase 12 OS=Homo sapiens OX=9606 GN=PDE12 PE=1 SV=2"	"0.000"	""	"12"	"7"	"12"	"7"	"609"	"67.3"	"6.57"	"2059.76"	"20.45"	"6"	"6"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf03372"	"201626"	"ENSG00000174840"	"PDE12"	"B4DTU8; hsa:201626; Q6L8Q7; Q8IYU3; Q8NDU2; Q8TE78"	"Phosphodiesterases in neuronal function"	"OAS antiviral response"	"2"	"0"	"344.8"	"278.4"	"332.4"	"400.9"	"281.6"	"307.3"	"708.8"	"767.7"	"1233.9"	"3480.7"	"4895.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y230"	"RuvB-like 2 OS=Homo sapiens OX=9606 GN=RUVBL2 PE=1 SV=3"	"0.000"	""	"17"	"7"	"14"	"7"	"463"	"51.1"	"5.64"	"2322.36"	"20.45"	"7"	"7"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06068, Pf17856"	"10856"	"ENSG00000183207"	"RUVBL2"	"B3KQ59; E7ETE5; hsa:10856; Q6FIB9; Q6PK27; Q9Y230; Q9Y361"	""	"HATs acetylate histones; Telomere Extension By Telomerase"	"2"	"0"	"356.1"	"338.7"	"452.2"	"580.0"	"344.3"	"377.6"	"571.2"	"529.2"	"717.0"	"1677.6"	"2525.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95218"	"Zinc finger Ran-binding domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ZRANB2 PE=1 SV=2"	"0.000"	""	"14"	"3"	"10"	"3"	"330"	"37.4"	"10.01"	"2645.29"	"20.39"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00641"	"9406"	"ENSG00000132485"	"ZRANB2"	"D3DQ75; hsa:9406; O95218; Q53GS3; Q59F92; Q5VV33; Q5VV34; Q8IXN6; Q9UP63"	""	""	"0"	"0"	"613.7"	"509.3"	"616.0"	"687.4"	"534.5"	"615.3"	"676.1"	"696.9"	"734.6"	"1130.7"	"1511.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53F19"	"Nuclear cap-binding protein subunit 3 OS=Homo sapiens OX=9606 GN=NCBP3 PE=1 SV=2"	"0.000"	""	"13"	"7"	"16"	"7"	"620"	"70.5"	"5.73"	"3035.31"	"20.38"	"7"	"6"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf10309"	"55421"	"ENSG00000074356"	"NCBP3"	"B3KWG7; hsa:55421; Q53F19; Q7L406; Q96FK1; Q9NXZ4"	""	""	"0"	"0"	"956.6"	"921.0"	"1150.0"	"1180.0"	"812.1"	"875.9"	"1135.1"	"1237.3"	"1334.0"	"2476.7"	"3647.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46776"	"60S ribosomal protein L27a OS=Homo sapiens OX=9606 GN=RPL27A PE=1 SV=2"	"0.000"	""	"28"	"5"	"12"	"5"	"148"	"16.6"	"11.00"	"2461.90"	"20.33"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf00828"	"6157"	"ENSG00000166441"	"RPL27A"	"B2R4B3; hsa:6157; P46776"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"656.7"	"504.6"	"842.5"	"1035.1"	"676.9"	"641.9"	"1043.3"	"1029.5"	"1193.2"	"2424.3"	"3928.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KR1"	"Zinc finger RNA-binding protein OS=Homo sapiens OX=9606 GN=ZFR PE=1 SV=2"	"0.000"	""	"6"	"6"	"11"	"6"	"1074"	"116.9"	"9.04"	"2912.88"	"20.28"	"6"	"5"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07528, Pf12874"	"51663"	"ENSG00000056097"	"ZFR"	"B2RNR5; hsa:51663; Q05C08; Q3B7X5; Q6P5A3; Q86UA0; Q96KR1; Q9H6V4; Q9NTI1; Q9Y687"	"Exercise-induced circadian regulation"	""	"1"	"0"	"755.2"	"677.7"	"843.9"	"974.3"	"715.9"	"755.9"	"950.4"	"970.7"	"1018.8"	"1462.0"	"2031.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30533"	"Alpha-2-macroglobulin receptor-associated protein OS=Homo sapiens OX=9606 GN=LRPAP1 PE=1 SV=1"	"0.000"	""	"24"	"8"	"13"	"8"	"357"	"41.4"	"8.78"	"2319.82"	"20.20"	"7"	"6"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf06400, Pf06401"	"4043"	"ENSG00000163956"	"LRPAP1"	"D3DVR9; hsa:4043; P30533; Q2M310; Q53HQ3; Q53HS6"	"Cholesterol metabolism"	""	"1"	"0"	"420.0"	"405.4"	"411.2"	"452.4"	"385.2"	"432.1"	"1328.8"	"1543.6"	"2447.7"	"4409.1"	"3547.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96F07"	"Cytoplasmic FMR1-interacting protein 2 OS=Homo sapiens OX=9606 GN=CYFIP2 PE=1 SV=2"	"0.000"	""	"6"	"7"	"15"	"1"	"1278"	"148.3"	"7.31"	"2840.79"	"20.08"	"7"	"6"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05994, Pf07159"	"26999"	"ENSG00000055163"	"CYFIP2"	"A6NLT2; D3DQJ3; hsa:26999; Q53EN5; Q96F07; Q9NTK4; Q9ULQ2; Q9UN29"	"Fragile X syndrome; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; RAC1 GTPase cycle; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"7"	"6"	"312.7"	"250.1"	"345.2"	"402.5"	"294.9"	"298.7"	"589.7"	"638.6"	"989.3"	"1798.0"	"2228.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNH7"	"Sorting nexin-6 OS=Homo sapiens OX=9606 GN=SNX6 PE=1 SV=1"	"0.000"	""	"10"	"5"	"7"	"5"	"406"	"46.6"	"6.16"	"748.38"	"20.07"	"2"	"5"	"transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787, Pf09325"	"58533"	"ENSG00000129515"	"SNX6"	"C0H5W9; hsa:58533; Q9UNH7; Q9Y449"	""	""	"0"	"0"	"217.7"	"208.9"	"242.3"	"320.8"	"200.8"	"188.9"	"408.3"	"412.0"	"574.8"	"2913.2"	"5011.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0C2"	"182 kDa tankyrase-1-binding protein OS=Homo sapiens OX=9606 GN=TNKS1BP1 PE=1 SV=4"	"0.000"	""	"4"	"5"	"10"	"5"	"1729"	"181.7"	"4.86"	"1950.98"	"20.04"	"5"	"5"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15327"	"85456"	"ENSG00000149115"	"TNKS1BP1"	"A7E2F8; hsa:85456; Q6PJ35; Q6ZV74; Q9C0C2"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"150.0"	"155.3"	"176.7"	"184.3"	"139.1"	"166.3"	"242.5"	"225.8"	"333.1"	"576.3"	"654.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YS7"	"C2 domain-containing protein 5 OS=Homo sapiens OX=9606 GN=C2CD5 PE=1 SV=1"	"0.000"	""	"9"	"6"	"8"	"6"	"1000"	"110.4"	"5.69"	"1107.77"	"19.99"	"3"	"5"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00168"	"9847"	"ENSG00000111731"	"C2CD5"	"B4DJ03; B4DRN7; B7ZLL0; F5H2A1; F5H5R1; hsa:9847; O60280; Q17RY7; Q7Z619; Q86SU3; Q86YS7"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"126.6"	"92.7"	"140.9"	"174.4"	"162.6"	"305.4"	"1018.3"	"1098.7"	"1324.7"	"1802.7"	"1887.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JSZ5"	"Protein PRRC2B OS=Homo sapiens OX=9606 GN=PRRC2B PE=1 SV=2"	"0.000"	""	"3"	"5"	"9"	"5"	"2229"	"242.8"	"8.34"	"1507.07"	"19.93"	"4"	"5"	"other biological processes"	""	""	"Pf07001"	"84726"	"ENSG00000288701"	"PRRC2B"	"hsa:84726; O60270; Q5JSZ5; Q5JSZ7; Q66VZ2; Q68CR0; Q96EI9; Q9H683"	""	""	"0"	"0"	"156.1"	"168.2"	"156.5"	"212.9"	"145.9"	"141.1"	"266.4"	"314.4"	"345.3"	"505.2"	"556.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3G5"	"Probable serine carboxypeptidase CPVL OS=Homo sapiens OX=9606 GN=CPVL PE=1 SV=2"	"0.000"	""	"9"	"3"	"7"	"3"	"476"	"54.1"	"5.62"	"1123.30"	"19.93"	"2"	"3"	"protein metabolism"	""	"other molecular function"	"Pf00450"	"54504"	"ENSG00000106066"	"CPVL"	"A4D1A4; hsa:54504; Q6UX20; Q8NBL7; Q96AR7; Q9H3G5; Q9HB41"	""	""	"0"	"0"	"80.1"	"69.9"	"101.6"	"119.1"	"83.6"	"92.5"	"247.5"	"266.0"	"466.1"	"2207.9"	"3963.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RP9"	"Elongation factor G, mitochondrial OS=Homo sapiens OX=9606 GN=GFM1 PE=1 SV=2"	"0.000"	""	"9"	"6"	"11"	"6"	"751"	"83.4"	"7.01"	"1200.49"	"19.90"	"4"	"6"	"protein metabolism;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf03144, Pf03764, Pf14492"	"85476"	"ENSG00000168827"	"GFM1"	"A6NCI9; B2RCB9; B3KRW1; hsa:85476; Q6GTN2; Q96RP9; Q96T39"	""	"Mitochondrial translation elongation"	"1"	"0"	"161.5"	"131.0"	"197.1"	"268.3"	"166.7"	"163.4"	"309.8"	"337.1"	"492.8"	"2383.8"	"3408.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAU0"	"Pleckstrin homology domain-containing family A member 5 OS=Homo sapiens OX=9606 GN=PLEKHA5 PE=1 SV=1"	"0.000"	""	"6"	"7"	"13"	"7"	"1116"	"127.4"	"7.53"	"2510.49"	"19.89"	"7"	"6"	"developmental processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169, Pf00397"	"54477"	"ENSG00000052126"	"PLEKHA5"	"A0JP03; B4DGS1; E9PHQ3; F5H0I0; hsa:54477; Q6NSF8; Q86ST7; Q8N3K6; Q96DY9; Q9BVR4; Q9C0H7; Q9H924; Q9HAU0; Q9NVK8"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"591.0"	"608.0"	"629.1"	"723.8"	"535.9"	"552.0"	"842.1"	"869.0"	"1053.6"	"1890.9"	"2239.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02878"	"60S ribosomal protein L6 OS=Homo sapiens OX=9606 GN=RPL6 PE=1 SV=3"	"0.000"	""	"17"	"6"	"12"	"6"	"288"	"32.7"	"10.58"	"2149.06"	"19.88"	"6"	"6"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01159, Pf03868"	"6128"	"ENSG00000089009"	"RPL6"	"hsa:6128; Q02878; Q2M3Q3; Q8WW97"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"703.5"	"801.7"	"750.4"	"1003.2"	"695.6"	"730.4"	"1104.0"	"1182.8"	"1433.3"	"2874.8"	"4412.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75528"	"Transcriptional adapter 3 OS=Homo sapiens OX=9606 GN=TADA3 PE=1 SV=1"	"0.000"	""	"10"	"2"	"5"	"2"	"432"	"48.9"	"6.27"	"544.75"	"19.82"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf10198"	"10474"	"ENSG00000171148"	"TADA3"	"hsa:10474; O75528; Q6FI83; Q9UFS2"	""	"Ub-specific processing proteases; Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"3"	"0"	"89.8"	"72.4"	"82.7"	"94.4"	"85.9"	"72.3"	"134.3"	"150.1"	"211.0"	"346.3"	"374.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16989"	"Y-box-binding protein 3 OS=Homo sapiens OX=9606 GN=YBX3 PE=1 SV=4"	"0.000"	""	"23"	"5"	"9"	"3"	"372"	"40.1"	"9.77"	"1373.13"	"19.78"	"4"	"5"	"stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00313"	"8531"	"ENSG00000060138"	"YBX3"	"B2RBW6; hsa:8531; P16989; Q14121; Q969N6; Q96B76"	"RalA downstream regulated genes; Apoptosis-related network due to altered Notch3 in ovarian cancer"	""	"2"	"0"	"118.4"	"106.8"	"132.4"	"151.0"	"115.0"	"128.9"	"197.7"	"219.8"	"291.4"	"529.3"	"720.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99733"	"Nucleosome assembly protein 1-like 4 OS=Homo sapiens OX=9606 GN=NAP1L4 PE=1 SV=1"	"0.000"	""	"15"	"5"	"9"	"3"	"375"	"42.8"	"4.69"	"1257.11"	"19.78"	"4"	"5"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"4676"	"ENSG00000205531; ENSG00000273562"	"NAP1L4"	"B2R6J4; F5HFY4; hsa:4676; Q99733"	""	""	"0"	"0"	"204.5"	"225.7"	"226.5"	"303.1"	"183.7"	"182.3"	"338.3"	"345.7"	"391.0"	"787.9"	"1226.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHR5"	"SAP30-binding protein OS=Homo sapiens OX=9606 GN=SAP30BP PE=1 SV=1"	"0.000"	""	"21"	"6"	"11"	"6"	"308"	"33.9"	"4.84"	"2165.65"	"19.72"	"5"	"6"	"other biological processes"	"cytoskeleton;nucleus"	""	"Pf07818"	"29115"	"ENSG00000161526"	"SAP30BP"	"B3KML7; hsa:29115; Q8N1R5; Q8TDR8; Q96D27; Q9UHR5"	""	"NoRC negatively regulates rRNA expression"	"1"	"0"	"367.8"	"297.4"	"381.4"	"437.7"	"324.6"	"336.8"	"455.1"	"454.5"	"549.0"	"1092.7"	"1593.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08865"	"40S ribosomal protein SA OS=Homo sapiens OX=9606 GN=RPSA PE=1 SV=4"	"0.000"	""	"23"	"5"	"8"	"5"	"295"	"32.8"	"4.87"	"782.33"	"19.70"	"2"	"5"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;translational apparatus;nucleus;other cell component"	"translation activity;other molecular function"	"Pf00318, Pf16122"	"3921"	"ENSG00000168028"	"RPSA"	"hsa:3921; P08865; P11085; P12030; Q16471; Q6IPD1; Q6IPD2; Q6NSD1; Q6NXQ8; Q86VC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"202.5"	"175.8"	"270.5"	"366.0"	"187.4"	"202.1"	"395.7"	"385.6"	"525.5"	"1153.7"	"1650.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ39"	"ATP-dependent RNA helicase DDX50 OS=Homo sapiens OX=9606 GN=DDX50 PE=1 SV=1"	"0.000"	""	"9"	"5"	"9"	"4"	"737"	"82.5"	"9.17"	"1373.67"	"19.66"	"4"	"5"	""	"plasma membrane;other membranes;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf08152"	"79009"	"ENSG00000107625"	"DDX50"	"hsa:79009; Q5VX37; Q8WV76; Q9BQ39; Q9BWI8"	""	""	"0"	"0"	"273.3"	"225.0"	"311.1"	"402.7"	"270.6"	"284.9"	"405.5"	"413.3"	"535.6"	"1165.6"	"1934.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWZ3"	"Ankyrin repeat and KH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ANKHD1 PE=1 SV=1"	"0.000"	""	"3"	"4"	"6"	"1"	"2542"	"269.3"	"5.73"	"1088.83"	"19.65"	"2"	"4"	"stress response"	"other cell component"	""	"Pf00013, Pf12796"	"404734; 54882"	"ENSG00000131503"	"ANKHD1"	"A6NH85; hsa:404734; hsa:54882; Q149P2; Q8IWZ2; Q8IWZ3; Q8WY90; Q96G77; Q96GK0; Q9H2U0; Q9HA95; Q9NWG4; Q9UPR7"	""	""	"0"	"0"	"7.7"	"9.5"	"6.1"	"10.9"	"7.1"	"5.4"	"17.8"	"17.1"	"20.3"	"42.7"	"42.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62241"	"40S ribosomal protein S8 OS=Homo sapiens OX=9606 GN=RPS8 PE=1 SV=2"	"0.000"	""	"27"	"6"	"11"	"6"	"208"	"24.2"	"10.32"	"1468.27"	"19.63"	"5"	"6"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01201"	"6202"	"ENSG00000142937"	"RPS8"	"hsa:6202; P09058; P62241; Q6IRL7"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"516.5"	"536.4"	"538.9"	"638.6"	"494.3"	"442.3"	"746.2"	"779.1"	"891.7"	"1641.6"	"2392.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62753"	"40S ribosomal protein S6 OS=Homo sapiens OX=9606 GN=RPS6 PE=1 SV=1"	"0.000"	""	"22"	"7"	"16"	"7"	"249"	"28.7"	"10.84"	"3051.26"	"19.63"	"7"	"5"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01092"	"6194"	"ENSG00000137154"	"RPS6"	"hsa:6194; P08227; P10660; P62753; Q4VBY7; Q8N6Z7"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MECP2 and associated Rett syndrome; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; Cytoplasmic ribosomal proteins; EGFR tyrosine kinase inhibitor resistance; IL-2 signaling pathway; Pleural mesothelioma; 2q37 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; mTORC1-mediated signalling; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Nuclear events stimulated by ALK signaling in cancer; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"47"	"0"	"1132.3"	"1078.7"	"1218.8"	"1462.3"	"1153.4"	"1129.9"	"1590.2"	"1638.6"	"1918.2"	"3243.9"	"4999.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13151"	"Heterogeneous nuclear ribonucleoprotein A0 OS=Homo sapiens OX=9606 GN=HNRNPA0 PE=1 SV=1"	"0.000"	""	"10"	"4"	"21"	"2"	"305"	"30.8"	"9.29"	"4648.80"	"19.62"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10949"	"ENSG00000177733"	"HNRNPA0"	"hsa:10949; Q13151; Q6IB18"	""	""	"0"	"0"	"664.4"	"664.8"	"765.7"	"919.6"	"569.3"	"593.6"	"833.8"	"865.0"	"906.8"	"1427.0"	"1958.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB8"	"Structural maintenance of chromosomes protein 6 OS=Homo sapiens OX=9606 GN=SMC6 PE=1 SV=2"	"0.000"	""	"6"	"6"	"13"	"6"	"1091"	"126.2"	"6.99"	"2736.34"	"19.61"	"6"	"6"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"79677"	"ENSG00000163029"	"SMC6"	"A8K8Q6; D6W518; hsa:79677; Q05BV4; Q96SB8; Q9H0X3; Q9H6M0"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"407.6"	"448.0"	"404.4"	"507.3"	"420.1"	"411.0"	"678.8"	"773.7"	"1000.3"	"2521.8"	"2906.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVI7"	"ATPase family AAA domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ATAD3A PE=1 SV=2"	"0.000"	""	"9"	"5"	"9"	"1"	"634"	"71.3"	"8.98"	"1659.98"	"19.52"	"4"	"5"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf12037"	"55210"	"ENSG00000197785"	"ATAD3A"	"B3KPB3; D2K8Q1; G3V1I6; hsa:55210; Q5SV23; Q8N275; Q96A50; Q9NVI7"	"1p36 copy number variation syndrome"	""	"1"	"0"	"24.0"	"25.3"	"38.1"	"44.1"	"29.5"	"29.4"	"63.8"	"59.9"	"85.8"	"198.3"	"326.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10515"	"Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLAT PE=1 SV=3"	"0.000"	""	"8"	"5"	"9"	"5"	"647"	"69.0"	"7.84"	"1479.75"	"19.49"	"4"	"5"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00198, Pf00364, Pf02817"	"1737"	"ENSG00000150768"	"DLAT"	"hsa:1737; P10515; Q16783; Q53EP3"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid"	"8"	"0"	"464.3"	"412.2"	"554.9"	"670.1"	"426.3"	"446.3"	"617.2"	"629.1"	"697.7"	"1308.9"	"1976.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96E11"	"Ribosome-recycling factor, mitochondrial OS=Homo sapiens OX=9606 GN=MRRF PE=1 SV=1"	"0.000"	""	"28"	"4"	"6"	"4"	"262"	"29.3"	"9.79"	"760.22"	"19.47"	"2"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity"	"Pf01765"	"92399"	"ENSG00000148187"	"MRRF"	"A8K6D8; A8K6Z4; B7Z4X5; B7Z6P7; hsa:92399; Q5RKT1; Q5T7T0; Q5T7T1; Q5T7T2; Q5T7T3; Q5T7T4; Q5T7T5; Q96E11"	""	"Mitochondrial translation termination"	"1"	"0"	"219.7"	"207.4"	"232.5"	"267.9"	"223.0"	"246.9"	"346.2"	"372.3"	"492.7"	"733.4"	"832.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWI9"	"MAX gene-associated protein OS=Homo sapiens OX=9606 GN=MGA PE=1 SV=4"	"0.000"	""	"2"	"6"	"11"	"6"	"3065"	"336.0"	"6.90"	"1787.76"	"19.47"	"5"	"6"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010, Pf00907, Pf16059"	"23269"	"ENSG00000174197"	"MGA"	"B9EGR5; E7ENI0; F5H7K2; hsa:23269; Q8IWI9; Q9H8R3; Q9H9N7; Q9UG69; Q9Y4E9"	"Pathways affected in adenoid cystic carcinoma"	"Transcriptional Regulation by E2F6"	"2"	"0"	"665.1"	"487.6"	"690.3"	"692.8"	"535.2"	"653.0"	"739.8"	"758.7"	"872.3"	"1444.3"	"1737.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43660"	"Pleiotropic regulator 1 OS=Homo sapiens OX=9606 GN=PLRG1 PE=1 SV=1"	"0.000"	""	"9"	"3"	"8"	"3"	"514"	"57.2"	"9.17"	"2042.97"	"19.42"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	"Pf00400"	"5356"	"ENSG00000171566"	"PLRG1"	"B3KMK4; hsa:5356; O43660; Q3KQY5; Q8WUD8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"89.6"	"121.1"	"90.5"	"119.9"	"100.3"	"92.7"	"198.1"	"262.9"	"361.5"	"1046.4"	"1146.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01130"	"Serine/arginine-rich splicing factor 2 OS=Homo sapiens OX=9606 GN=SRSF2 PE=1 SV=4"	"0.000"	""	"14"	"3"	"7"	"3"	"221"	"25.5"	"11.85"	"1095.17"	"19.36"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6427"	"ENSG00000161547"	"SRSF2"	"B3KWD5; B4DN89; H0YG49; hsa:6427; Q01130"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Minor Pathway"	"7"	"0"	"308.9"	"298.2"	"314.1"	"438.8"	"244.2"	"248.3"	"379.3"	"409.2"	"442.0"	"867.9"	"1255.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75494"	"Serine/arginine-rich splicing factor 10 OS=Homo sapiens OX=9606 GN=SRSF10 PE=1 SV=1"	"0.000"	""	"18"	"4"	"9"	"2"	"262"	"31.3"	"11.27"	"1740.50"	"19.35"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"10772"	"ENSG00000188529"	"SRSF10"	"A6NFM6; A6NI42; A6NIU7; B4DJP9; hsa:10772; O60572; O75494; Q5JRH9; Q5JRI0; Q5JRI2; Q5JRI3; Q5JRI4; Q96G09; Q96P17"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"3"	"2"	"240.1"	"236.7"	"267.3"	"391.2"	"229.2"	"208.4"	"384.4"	"393.2"	"479.3"	"999.0"	"1332.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13347"	"Eukaryotic translation initiation factor 3 subunit I OS=Homo sapiens OX=9606 GN=EIF3I PE=1 SV=1"	"0.000"	""	"18"	"5"	"9"	"5"	"325"	"36.5"	"5.64"	"1503.71"	"19.21"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00400"	"8668"	"ENSG00000084623"	"EIF3I"	"hsa:8668; Q13347"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"173.7"	"162.6"	"232.1"	"285.9"	"182.7"	"177.4"	"318.5"	"333.0"	"419.8"	"904.4"	"2167.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00629"	"Importin subunit alpha-3 OS=Homo sapiens OX=9606 GN=KPNA4 PE=1 SV=1"	"0.000"	""	"7"	"2"	"5"	"1"	"521"	"57.9"	"4.96"	"626.66"	"19.20"	"1"	"2"	"cell-cell signaling;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3840"	"ENSG00000186432"	"KPNA4"	"A8K4S6; D3DNM2; hsa:3840; O00190; O00629"	"Leptin signaling pathway"	"ISG15 antiviral mechanism; NS1 Mediated Effects on Host Pathways"	"3"	"0"	"8.8"	"11.8"	"16.4"	"31.8"	"10.5"	"11.2"	"33.7"	"36.4"	"46.0"	"159.1"	"304.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3Y2"	"Chromatin target of PRMT1 protein OS=Homo sapiens OX=9606 GN=CHTOP PE=1 SV=2"	"0.000"	""	"18"	"4"	"10"	"4"	"248"	"26.4"	"12.23"	"2271.60"	"19.18"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf13865"	"26097"	"ENSG00000160679"	"CHTOP"	"D3DV55; hsa:26097; Q0VAQ8; Q2VPI9; Q5T7Y8; Q5T7Y9; Q5T7Z0; Q6NSM4; Q6PB28; Q8WYT9; Q9BUC5; Q9H034; Q9H2L0; Q9Y3Y2"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"704.5"	"639.6"	"854.7"	"1143.9"	"676.4"	"683.2"	"1099.5"	"1103.0"	"1304.6"	"2563.8"	"4221.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15511"	"Actin-related protein 2/3 complex subunit 5 OS=Homo sapiens OX=9606 GN=ARPC5 PE=1 SV=3"	"0.000"	""	"26"	"4"	"14"	"3"	"151"	"16.3"	"5.67"	"2780.83"	"19.10"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf04699"	"10092"	"ENSG00000162704"	"ARPC5"	"A6NEC4; hsa:10092; O15511; Q6PG42"	"Pathogenic Escherichia coli infection; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Neutrophil degranulation; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"8"	"0"	"275.5"	"292.3"	"283.4"	"345.9"	"264.0"	"277.8"	"766.9"	"831.6"	"1634.2"	"4433.6"	"5550.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94776"	"Metastasis-associated protein MTA2 OS=Homo sapiens OX=9606 GN=MTA2 PE=1 SV=1"	"0.000"	""	"9"	"5"	"10"	"5"	"668"	"75.0"	"9.66"	"2002.59"	"19.08"	"5"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf01426, Pf01448, Pf17226"	"9219"	"ENSG00000149480"	"MTA2"	"hsa:9219; O94776; Q68DB1; Q9UQB5"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"334.6"	"273.5"	"361.3"	"448.0"	"268.6"	"304.1"	"566.6"	"594.0"	"758.8"	"1743.2"	"2471.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2U2"	"Inorganic pyrophosphatase 2, mitochondrial OS=Homo sapiens OX=9606 GN=PPA2 PE=1 SV=2"	"0.000"	""	"19"	"4"	"6"	"4"	"334"	"37.9"	"7.39"	"1093.77"	"19.08"	"2"	"4"	"other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00719"	"27068"	"ENSG00000138777"	"PPA2"	"B4DLP7; F8WDN9; hsa:27068; I6L9B6; Q4W5E9; Q6PG51; Q8TBW0; Q96E55; Q9H0T0; Q9H2U2; Q9NX37; Q9P033; Q9ULX0"	""	"Mitochondrial tRNA aminoacylation; Pyrophosphate hydrolysis"	"2"	"0"	"46.3"	"47.6"	"62.9"	"69.0"	"49.9"	"46.1"	"127.9"	"121.6"	"172.3"	"1149.7"	"2415.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22061"	"Protein-L-isoaspartate(D-aspartate) O-methyltransferase OS=Homo sapiens OX=9606 GN=PCMT1 PE=1 SV=4"	"0.000"	""	"26"	"6"	"13"	"6"	"227"	"24.6"	"7.21"	"2604.91"	"19.03"	"6"	"5"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01135"	"5110"	"ENSG00000120265"	"PCMT1"	"A8K109; hsa:5110; J3KP72; P22061; Q14661; Q16556; Q5VYC1; Q5VYC2; Q93061; Q96II9; Q99625; Q9BQV7; Q9BQV8; Q9NP03"	"Primary ovarian insufficiency"	"Protein repair"	"2"	"0"	"843.1"	"865.4"	"1207.6"	"1397.3"	"912.7"	"916.2"	"1303.7"	"1334.7"	"1523.1"	"2017.4"	"2130.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62195"	"26S proteasome regulatory subunit 8 OS=Homo sapiens OX=9606 GN=PSMC5 PE=1 SV=1"	"0.000"	""	"20"	"5"	"7"	"5"	"406"	"45.6"	"7.55"	"1279.23"	"19.01"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf16450, Pf17862"	"5705"	"ENSG00000087191"	"PSMC5"	"A8K3Z3; A8K763; hsa:5705; O35051; O43208; P47210; P52915; P52916; P62195"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Alzheimer's disease"	"ABC-family proteins mediated transport; Regulation of expression of SLITs and ROBOs; Ub-specific processing proteases; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Interleukin-1 signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"141.0"	"130.0"	"177.5"	"273.0"	"137.5"	"138.6"	"250.5"	"267.8"	"281.6"	"681.4"	"1334.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62841"	"40S ribosomal protein S15 OS=Homo sapiens OX=9606 GN=RPS15 PE=1 SV=2"	"0.000"	""	"23"	"2"	"7"	"2"	"145"	"17.0"	"10.39"	"924.11"	"18.99"	"1"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00203"	"6209"	"ENSG00000115268"	"RPS15"	"A5D8V9; hsa:6209; P11174; P62841; Q3KRA1; Q9UDC2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"334.2"	"301.0"	"342.4"	"444.4"	"272.8"	"314.5"	"412.9"	"434.9"	"499.9"	"932.8"	"1344.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6I9Y2"	"THO complex subunit 7 homolog OS=Homo sapiens OX=9606 GN=THOC7 PE=1 SV=3"	"0.000"	""	"29"	"5"	"10"	"5"	"204"	"23.7"	"5.67"	"1973.60"	"18.98"	"5"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05615"	"80145"	"ENSG00000163634"	"THOC7"	"hsa:80145; Q6I9Y2; Q6P1L3; Q8WUF2; Q9H5H0"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"534.7"	"496.1"	"580.0"	"635.8"	"492.6"	"531.1"	"707.3"	"709.9"	"848.5"	"1498.5"	"2041.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CT7"	"Coiled-coil domain-containing protein 124 OS=Homo sapiens OX=9606 GN=CCDC124 PE=1 SV=1"	"0.000"	""	"29"	"5"	"9"	"5"	"223"	"25.8"	"9.54"	"1677.33"	"18.96"	"4"	"5"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf06244"	"115098"	"ENSG00000007080"	"CCDC124"	"hsa:115098; Q96CT7"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"582.0"	"486.9"	"568.8"	"652.8"	"530.7"	"566.4"	"758.0"	"805.1"	"954.9"	"1124.4"	"1004.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15436"	"Protein transport protein Sec23A OS=Homo sapiens OX=9606 GN=SEC23A PE=1 SV=2"	"0.000"	""	"9"	"4"	"6"	"4"	"765"	"86.1"	"7.08"	"915.29"	"18.90"	"2"	"4"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10484"	"ENSG00000100934"	"SEC23A"	"B2R5P4; B3KXI2; hsa:10484; Q15436; Q8NE16"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; MHC class II antigen presentation; SARS-CoV-2 activates/modulates innate and adaptive immune responses; COPII-mediated vesicle transport; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"7"	"0"	"177.0"	"168.9"	"176.3"	"205.8"	"171.3"	"177.4"	"227.3"	"210.1"	"272.5"	"547.8"	"862.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62280"	"40S ribosomal protein S11 OS=Homo sapiens OX=9606 GN=RPS11 PE=1 SV=3"	"0.000"	""	"31"	"5"	"12"	"5"	"158"	"18.4"	"10.30"	"2224.57"	"18.87"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00366, Pf16205"	"6205"	"ENSG00000142534"	"RPS11"	"B2R4F5; hsa:6205; P04643; P62280; Q498Y6; Q6IRY0"	"VEGFA-VEGFR2 signaling; IL-18 signaling pathway; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"21"	"0"	"932.3"	"732.7"	"1049.3"	"1222.5"	"870.7"	"878.0"	"1253.4"	"1245.2"	"1432.9"	"2757.8"	"4692.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16104"	"Histone H2AX OS=Homo sapiens OX=9606 GN=H2AX PE=1 SV=2"	"0.000"	""	"32"	"3"	"9"	"1"	"143"	"15.1"	"10.74"	"1596.00"	"18.87"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125, Pf16211"	"3014"	"ENSG00000188486"	"H2AX"	"hsa:3014; P16104; Q4ZGJ7; Q6IAS5"	"miRNA regulation of DNA damage response; miRNAs involved in DNA damage response; Proteasome degradation; ATM signaling in development and disease ; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; DNA repair pathways, full network; 5q35 copy number variation; DNA damage response"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; RMTs methylate histone arginines; Amyloid fiber formation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Oxidative Stress Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; Meiotic synapsis; Transcriptional regulation by small RNAs; Deposition of new CENPA-containing nucleosomes at the centromere; B-WICH complex positively regulates rRNA expression; Formation of the beta-catenin:TCF transactivating complex; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; G2/M DNA damage checkpoint; RNA Polymerase I Promoter Escape; Meiotic recombination; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; SIRT1 negatively regulates rRNA expression; PRC2 methylates histones and DNA; Assembly of the ORC complex at the origin of replication; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; Defective pyroptosis; Packaging Of Telomere Ends; Condensation of Prophase Chromosomes; DNA Damage/Telomere Stress Induced Senescence; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; DNA methylation; Nonhomologous End-Joining (NHEJ); RNA Polymerase I Promoter Opening; Transcriptional regulation of granulopoiesis"	"46"	"0"	"16.5"	"14.9"	"20.5"	"23.7"	"16.9"	"21.1"	"22.8"	"30.1"	"30.6"	"66.7"	"87.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0C8"	"Integrin-linked kinase-associated serine/threonine phosphatase 2C OS=Homo sapiens OX=9606 GN=ILKAP PE=1 SV=1"	"0.000"	""	"12"	"5"	"12"	"5"	"392"	"42.9"	"7.09"	"2237.72"	"18.86"	"5"	"5"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00481"	"80895"	"ENSG00000132323"	"ILKAP"	"B3KM39; hsa:80895; Q9H0C8"	"2q37 copy number variation syndrome"	""	"1"	"0"	"209.4"	"175.2"	"224.7"	"303.1"	"184.2"	"189.6"	"623.5"	"691.2"	"1282.4"	"4077.7"	"5118.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14011"	"Cold-inducible RNA-binding protein OS=Homo sapiens OX=9606 GN=CIRBP PE=1 SV=1"	"0.000"	""	"27"	"3"	"6"	"3"	"172"	"18.6"	"9.51"	"713.44"	"18.84"	"2"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"1153"	"ENSG00000099622"	"CIRBP"	"B3KT17; B4E2X2; hsa:1153; Q14011"	""	""	"0"	"0"	"517.6"	"592.0"	"569.1"	"595.9"	"489.1"	"508.5"	"676.1"	"648.0"	"722.7"	"1033.7"	"1479.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWX8"	"Calcium homeostasis endoplasmic reticulum protein OS=Homo sapiens OX=9606 GN=CHERP PE=1 SV=3"	"0.000"	""	"7"	"6"	"9"	"6"	"916"	"103.6"	"9.04"	"1133.64"	"18.79"	"4"	"5"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01585, Pf01805, Pf04818"	"10523"	"ENSG00000085872"	"CHERP"	"hsa:10523; O00302; Q4G0Y5; Q8IWX8; Q8WU30; Q99492"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"643.4"	"595.4"	"610.9"	"782.2"	"558.8"	"580.0"	"814.5"	"879.3"	"953.2"	"2144.9"	"3247.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00231"	"26S proteasome non-ATPase regulatory subunit 11 OS=Homo sapiens OX=9606 GN=PSMD11 PE=1 SV=3"	"0.000"	""	"18"	"5"	"9"	"5"	"422"	"47.4"	"6.48"	"1702.90"	"18.77"	"4"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01399, Pf18055, Pf18503"	"5717"	"ENSG00000108671"	"PSMD11"	"A8K3I7; E1P663; hsa:5717; O00231; O00495; Q53FT5"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; VEGFA-VEGFR2 signaling"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"103.8"	"111.1"	"136.7"	"162.1"	"114.4"	"116.3"	"220.7"	"241.2"	"337.7"	"1169.7"	"2089.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14635"	"G2/mitotic-specific cyclin-B1 OS=Homo sapiens OX=9606 GN=CCNB1 PE=1 SV=1"	"0.000"	""	"11"	"4"	"10"	"4"	"433"	"48.3"	"7.47"	"2359.01"	"18.73"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00134, Pf02984"	"891"	"ENSG00000134057"	"CCNB1"	"A8K066; hsa:891; P14635; Q5TZP9"	"AMP-activated protein kinase signaling; miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATM signaling pathway; G1 to S cell cycle control; GDNF signaling; DNA damage response"	"The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Transcriptional regulation by RUNX2; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; Initiation of Nuclear Envelope (NE) Reformation; Polo-like kinase mediated events; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Phosphorylation of Emi1"	"31"	"0"	"420.6"	"365.6"	"444.0"	"518.0"	"360.6"	"392.1"	"641.9"	"661.6"	"900.0"	"1717.3"	"1985.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16795"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 9, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA9 PE=1 SV=2"	"0.000"	""	"12"	"3"	"8"	"3"	"377"	"42.5"	"9.80"	"1806.96"	"18.72"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01370"	"4704"	"ENSG00000139180"	"NDUFA9"	"hsa:4704; Q14076; Q16795; Q2NKX0"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"97.6"	"82.0"	"130.9"	"161.7"	"85.3"	"109.8"	"204.0"	"219.8"	"342.8"	"822.6"	"1053.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKM9"	"RNA-binding protein Raly OS=Homo sapiens OX=9606 GN=RALY PE=1 SV=1"	"0.000"	""	"25"	"7"	"12"	"7"	"306"	"32.4"	"9.17"	"2289.82"	"18.64"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"22913"	"ENSG00000125970"	"RALY"	"hsa:22913; Q14621; Q2M365; Q5QPL8; Q9BQX6; Q9UJE3; Q9UKM9"	""	""	"0"	"0"	"833.9"	"687.2"	"970.3"	"1388.7"	"705.8"	"712.1"	"1234.6"	"1272.7"	"1546.4"	"3032.3"	"4507.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62995"	"Transformer-2 protein homolog beta OS=Homo sapiens OX=9606 GN=TRA2B PE=1 SV=1"	"0.000"	""	"19"	"6"	"11"	"6"	"288"	"33.6"	"11.25"	"1845.39"	"18.61"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6434"	"ENSG00000136527"	"TRA2B"	"B4DVK2; D3DNU3; hsa:6434; O15449; P62995; Q15815; Q64283"	"mRNA processing"	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"5"	"0"	"1198.7"	"1199.1"	"1279.8"	"1536.0"	"1009.0"	"1039.1"	"1376.8"	"1426.4"	"1384.3"	"2125.9"	"3128.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31689"	"DnaJ homolog subfamily A member 1 OS=Homo sapiens OX=9606 GN=DNAJA1 PE=1 SV=2"	"0.000"	""	"19"	"5"	"8"	"4"	"397"	"44.8"	"7.08"	"1614.10"	"18.61"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf00684, Pf01556"	"3301"	"ENSG00000086061"	"DNAJA1"	"hsa:3301; P31689; Q5T7Q0; Q86TL9"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"3"	"1"	"302.3"	"269.7"	"349.5"	"511.2"	"293.8"	"262.0"	"544.0"	"587.3"	"813.2"	"1826.2"	"2477.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95208"	"Epsin-2 OS=Homo sapiens OX=9606 GN=EPN2 PE=1 SV=3"	"0.000"	""	"8"	"6"	"11"	"6"	"641"	"68.4"	"7.52"	"1701.24"	"18.60"	"5"	"6"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"22905"	"ENSG00000072134"	"EPN2"	"A8MTV8; B3KRX8; E9PBC2; hsa:22905; O95207; O95208; Q52LD0; Q9H7Z2; Q9UPT7"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"91.7"	"139.3"	"223.0"	"352.7"	"298.2"	"318.8"	"479.3"	"468.9"	"539.1"	"736.6"	"924.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09622"	"Dihydrolipoyl dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=DLD PE=1 SV=2"	"0.000"	""	"16"	"5"	"9"	"5"	"509"	"54.1"	"7.85"	"1792.32"	"18.60"	"4"	"5"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02852, Pf07992"	"1738"	"ENSG00000091140"	"DLD"	"B2R5X0; B4DHG0; B4DT69; hsa:1738; P09622; Q14131; Q14167; Q59EV8; Q8WTS4"	"Fatty acid beta-oxidation; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Tryptophan metabolism; 7q11.23 copy number variation syndrome; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; 10q11.21q11.23 copy number variation syndrome; Metabolic Epileptic Disorders; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Regulation of pyruvate dehydrogenase (PDH) complex; Signaling by Retinoic Acid; Citric acid cycle (TCA cycle); Branched-chain amino acid catabolism; Glycine degradation"	"18"	"0"	"269.9"	"204.9"	"254.2"	"337.0"	"249.5"	"281.0"	"404.0"	"399.4"	"595.1"	"1939.6"	"2855.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49321"	"Nuclear autoantigenic sperm protein OS=Homo sapiens OX=9606 GN=NASP PE=1 SV=2"	"0.000"	""	"8"	"6"	"10"	"6"	"788"	"85.2"	"4.30"	"1518.12"	"18.59"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10516"	"4678"	"ENSG00000132780"	"NASP"	"A8K6H2; B4DQP3; D3DQ07; F5H3J2; hsa:4678; P49321; Q53GW5; Q5T622; Q5T625; Q96A69; Q9BTW2"	""	""	"0"	"0"	"743.4"	"594.1"	"741.6"	"917.3"	"628.4"	"695.5"	"904.6"	"926.5"	"1037.5"	"1644.8"	"2143.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P80303"	"Nucleobindin-2 OS=Homo sapiens OX=9606 GN=NUCB2 PE=1 SV=3"	"0.000"	""	"17"	"5"	"9"	"5"	"420"	"50.2"	"5.12"	"1945.42"	"18.57"	"5"	"4"	"signal transduction"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4925"	"ENSG00000070081"	"NUCB2"	"A8K642; D3DQX5; hsa:4925; P80303; Q8NFT5; V9HW75"	""	""	"0"	"0"	"381.2"	"312.1"	"366.1"	"473.0"	"322.6"	"351.9"	"524.1"	"537.5"	"663.0"	"1223.7"	"1443.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09012"	"U1 small nuclear ribonucleoprotein A OS=Homo sapiens OX=9606 GN=SNRPA PE=1 SV=3"	"0.000"	""	"8"	"3"	"14"	"1"	"282"	"31.3"	"9.83"	"2272.64"	"18.53"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6626"	"ENSG00000077312"	"SNRPA"	"hsa:6626; P09012"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"3"	"1859.2"	"1357.1"	"1965.5"	"2295.4"	"1476.5"	"1523.8"	"1951.0"	"1905.6"	"2009.7"	"2313.4"	"3290.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15370"	"Elongin-B OS=Homo sapiens OX=9606 GN=ELOB PE=1 SV=1"	"0.000"	""	"53"	"5"	"9"	"5"	"118"	"13.1"	"4.88"	"1637.64"	"18.53"	"4"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00240"	"6923"	"ENSG00000103363"	"ELOB"	"B7WPD3; hsa:6923; Q15370"	"Dual hijack model of Vif in HIV infection; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2; Modulators of TCR signaling and T cell activation"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Inactivation of CSF3 (G-CSF) signaling; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"21"	"0"	"565.3"	"502.4"	"658.6"	"879.8"	"549.0"	"548.3"	"947.2"	"981.3"	"1309.0"	"2649.2"	"3379.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ16"	"Dynamin-3 OS=Homo sapiens OX=9606 GN=DNM3 PE=1 SV=4"	"0.000"	""	"5"	"4"	"11"	"1"	"869"	"97.7"	"8.35"	"2077.99"	"18.52"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00169, Pf00350, Pf01031, Pf02212"	"26052"	"ENSG00000197959"	"DNM3"	"A9Z1Y1; hsa:26052; O14982; O95555; Q1MTM8; Q5W129; Q6P2G1; Q9H0P3; Q9H548; Q9NQ68; Q9NQN6; Q9UQ16"	"Synaptic vesicle pathway; Alstrom syndrome; 15q25 copy number variation"	"Clathrin-mediated endocytosis; Recycling pathway of L1; MHC class II antigen presentation; Retrograde neurotrophin signalling; Toll Like Receptor 4 (TLR4) Cascade"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPW8"	"Protein NipSnap homolog 1 OS=Homo sapiens OX=9606 GN=NIPSNAP1 PE=1 SV=1"	"0.000"	""	"19"	"4"	"7"	"3"	"284"	"33.3"	"9.31"	"1575.19"	"18.52"	"3"	"4"	"other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf07978"	"8508"	"ENSG00000184117"	"NIPSNAP1"	"B2RAY3; hsa:8508; O43800; Q9BPW8"	""	""	"0"	"0"	"90.0"	"79.4"	"111.9"	"143.7"	"92.1"	"100.8"	"156.1"	"173.0"	"210.5"	"502.3"	"581.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15226"	"NF-kappa-B-repressing factor OS=Homo sapiens OX=9606 GN=NKRF PE=1 SV=2"	"0.000"	""	"11"	"6"	"10"	"6"	"690"	"77.6"	"8.79"	"2161.13"	"18.48"	"5"	"5"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01424, Pf01585"	"55922"	"ENSG00000186416"	"NKRF"	"G3V1N1; hsa:55922; O15226; Q4VC41; Q9UJ91"	"Pathogenesis of SARS-CoV-2 mediated by nsp9-nsp10 complex; Network map of SARS-CoV-2 signaling pathway"	""	"2"	"0"	"363.2"	"347.4"	"378.7"	"457.8"	"328.9"	"344.1"	"493.5"	"489.5"	"601.5"	"1077.4"	"1495.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16555"	"Dihydropyrimidinase-related protein 2 OS=Homo sapiens OX=9606 GN=DPYSL2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"3"	"572"	"62.3"	"6.38"	"1179.23"	"18.48"	"1"	"3"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf01979"	"1808"	"ENSG00000092964"	"DPYSL2"	"A8K5H2; B4DR31; D3DSS7; hsa:1808; O00424; Q16555"	"Microtubule cytoskeleton regulation; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"Recycling pathway of L1; CRMPs in Sema3A signaling"	"4"	"0"	"16.5"	"12.2"	"26.0"	"35.4"	"22.4"	"20.9"	"37.1"	"42.7"	"59.7"	"253.4"	"583.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ST3"	"Paired amphipathic helix protein Sin3a OS=Homo sapiens OX=9606 GN=SIN3A PE=1 SV=2"	"0.000"	""	"7"	"7"	"10"	"7"	"1273"	"145.1"	"7.25"	"1318.33"	"18.47"	"4"	"6"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02671, Pf08295, Pf16879"	"25942"	"ENSG00000169375"	"SIN3A"	"B2RNS5; hsa:25942; Q8N8N4; Q8NC83; Q8WV18; Q96L98; Q96ST3; Q9UFQ1"	"Androgen receptor signaling pathway; Retinoblastoma gene in cancer; MECP2 and associated Rett syndrome; Transcription co-factors SKI and SKIL protein partners; Hedgehog signaling pathway; 15q11q13 copy number variation"	"Factors involved in megakaryocyte development and platelet production; NoRC negatively regulates rRNA expression; MECP2 regulates neuronal receptors and channels; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SUMOylation of transcription cofactors; Cytoprotection by HMOX1; MECP2 regulates transcription of neuronal ligands; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Regulation of lipid metabolism by PPARalpha; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; Loss of MECP2 binding ability to 5mC-DNA"	"18"	"0"	"193.1"	"180.6"	"216.8"	"247.2"	"168.8"	"195.3"	"348.9"	"346.8"	"503.5"	"1423.5"	"2333.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NB3"	"Zinc finger protein 830 OS=Homo sapiens OX=9606 GN=ZNF830 PE=1 SV=2"	"0.000"	""	"20"	"6"	"10"	"5"	"372"	"42.0"	"5.31"	"1373.35"	"18.40"	"4"	"6"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"91603"	"ENSG00000198783"	"ZNF830"	"hsa:91603; Q96F60; Q96GZ5; Q96NB3; Q9BU38"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"6"	"0"	"187.6"	"163.7"	"225.7"	"241.8"	"178.0"	"179.2"	"236.4"	"233.3"	"292.9"	"617.6"	"870.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4E8"	"Ubiquitin carboxyl-terminal hydrolase 15 OS=Homo sapiens OX=9606 GN=USP15 PE=1 SV=3"	"0.000"	""	"7"	"6"	"12"	"6"	"981"	"112.3"	"5.22"	"2361.18"	"18.35"	"6"	"6"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00443, Pf06337, Pf14533, Pf14836"	"9958"	"ENSG00000135655"	"USP15"	"hsa:9958; Q08AL5; Q9H8G9; Q9HCA6; Q9UNP0; Q9Y4E8; Q9Y5B5"	""	"Ub-specific processing proteases; UCH proteinases; Downregulation of TGF-beta receptor signaling"	"3"	"0"	"569.3"	"509.0"	"605.4"	"829.2"	"514.2"	"499.0"	"868.1"	"925.5"	"1092.5"	"1699.4"	"2009.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH4"	"Nucleoporin Nup37 OS=Homo sapiens OX=9606 GN=NUP37 PE=1 SV=1"	"0.000"	""	"19"	"4"	"8"	"4"	"326"	"36.7"	"5.92"	"2024.51"	"18.25"	"4"	"4"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"79023"	"ENSG00000075188"	"NUP37"	"hsa:79023; Q8NFH4; Q9H644"	""	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"263.8"	"238.0"	"302.0"	"367.1"	"292.7"	"267.3"	"493.2"	"510.1"	"650.3"	"1159.2"	"1565.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05387"	"60S acidic ribosomal protein P2 OS=Homo sapiens OX=9606 GN=RPLP2 PE=1 SV=1"	"0.000"	""	"46"	"4"	"11"	"3"	"115"	"11.7"	"4.54"	"2590.28"	"18.21"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00428"	"6181"	"ENSG00000177600"	"RPLP2"	"hsa:6181; P05387; Q6FG96"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins; Opioid receptor pathways"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"1"	"309.0"	"297.4"	"343.9"	"615.2"	"264.9"	"290.8"	"577.1"	"644.1"	"802.3"	"1644.9"	"2305.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14980"	"Exportin-1 OS=Homo sapiens OX=9606 GN=XPO1 PE=1 SV=1"	"0.000"	""	"5"	"4"	"9"	"4"	"1071"	"123.3"	"6.06"	"1529.61"	"18.17"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03810, Pf08389, Pf08767, Pf18777, Pf18784, Pf18787"	"7514"	"ENSG00000082898"	"XPO1"	"A6NL14; A8K1K5; D6W5E2; hsa:7514; O14980; Q63HP8; Q68CP3; Q99433"	"eIF5A regulation in response to inhibition of the nuclear export system; 22q11.2 copy number variation syndrome"	"Separation of Sister Chromatids; MAPK6/MAPK4 signaling; NPAS4 regulates expression of target genes; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Heme signaling; Deactivation of the beta-catenin transactivating complex; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Downregulation of TGF-beta receptor signaling; HuR (ELAVL1) binds and stabilizes mRNA; Cyclin A/B1/B2 associated events during G2/M transition"	"18"	"0"	"17.7"	"27.9"	"28.9"	"36.6"	"22.2"	"20.6"	"65.8"	"72.6"	"126.0"	"703.0"	"1052.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B9"	"RRP15-like protein OS=Homo sapiens OX=9606 GN=RRP15 PE=1 SV=2"	"0.000"	""	"20"	"5"	"9"	"5"	"282"	"31.5"	"5.52"	"1236.58"	"18.17"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	""	"Pf07890"	"51018"	"ENSG00000067533"	"RRP15"	"hsa:51018; Q9Y3B9"	""	""	"0"	"0"	"272.9"	"220.9"	"322.2"	"424.1"	"282.0"	"297.3"	"425.5"	"426.3"	"504.4"	"868.2"	"1208.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07020"	"60S ribosomal protein L18 OS=Homo sapiens OX=9606 GN=RPL18 PE=1 SV=2"	"0.000"	""	"19"	"4"	"10"	"4"	"188"	"21.6"	"11.72"	"1820.07"	"18.15"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf17135"	"6141"	"ENSG00000063177"	"RPL18"	"F8VWC5; hsa:6141; Q07020; Q8WTZ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"240.2"	"222.7"	"314.3"	"420.5"	"264.8"	"254.3"	"420.0"	"445.9"	"561.6"	"1078.5"	"1788.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQG0"	"Myb-binding protein 1A OS=Homo sapiens OX=9606 GN=MYBBP1A PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"1328"	"148.8"	"9.28"	"1058.03"	"18.12"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04931"	"10514"	"ENSG00000132382"	"MYBBP1A"	"hsa:10514; Q86VM3; Q9BQG0; Q9BW49; Q9P0V5; Q9UF99"	"Energy metabolism; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression"	"3"	"0"	"17.6"	"18.9"	"24.6"	"28.2"	"15.9"	"18.3"	"35.3"	"31.1"	"49.7"	"91.7"	"119.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41250"	"Glycine--tRNA ligase OS=Homo sapiens OX=9606 GN=GARS1 PE=1 SV=3"	"0.000"	""	"9"	"6"	"9"	"5"	"739"	"83.1"	"7.03"	"1348.66"	"18.11"	"4"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"non-structural extracellular;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00458, Pf00587, Pf03129"	"2617"	"ENSG00000106105"	"GARS1"	"A0A090N8G0; B3KQA2; B4DIA0; hsa:2617; P41250; Q969Y1"	""	"Cytosolic tRNA aminoacylation; Mitochondrial tRNA aminoacylation"	"2"	"0"	"310.0"	"212.3"	"400.2"	"469.4"	"282.0"	"289.8"	"466.3"	"452.8"	"536.2"	"1787.4"	"4698.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16629"	"Serine/arginine-rich splicing factor 7 OS=Homo sapiens OX=9606 GN=SRSF7 PE=1 SV=1"	"0.000"	""	"23"	"4"	"9"	"4"	"238"	"27.4"	"11.82"	"820.43"	"18.11"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6432"	"ENSG00000115875"	"SRSF7"	"B4DLU6; G5E9M3; hsa:6432; Q16629; Q564D3"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"7"	"0"	"564.4"	"695.6"	"571.8"	"845.2"	"529.2"	"489.8"	"871.2"	"967.9"	"1025.8"	"1968.5"	"2560.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH5"	"Nucleoporin NUP35 OS=Homo sapiens OX=9606 GN=NUP35 PE=1 SV=1"	"0.000"	""	"23"	"6"	"11"	"6"	"326"	"34.8"	"9.09"	"2190.75"	"18.10"	"5"	"5"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf05172"	"129401"	"ENSG00000163002"	"NUP35"	"B4DP57; B4DYB4; hsa:129401; Q4ZFZ9; Q53S95; Q8NFH5; Q8TDJ1"	""	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Early Events; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	"560.0"	"560.6"	"520.3"	"606.6"	"484.0"	"528.4"	"739.7"	"791.8"	"875.9"	"1668.9"	"2291.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14160"	"Protein scribble homolog OS=Homo sapiens OX=9606 GN=SCRIB PE=1 SV=4"	"0.000"	""	"5"	"4"	"6"	"4"	"1630"	"174.8"	"5.07"	"724.70"	"18.05"	"2"	"4"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"231.3"	"197.6"	"235.4"	"281.0"	"163.0"	"216.8"	"308.3"	"300.0"	"362.9"	"881.0"	"1373.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37802"	"Transgelin-2 OS=Homo sapiens OX=9606 GN=TAGLN2 PE=1 SV=3"	"0.000"	""	"36"	"5"	"8"	"5"	"199"	"22.4"	"8.25"	"1171.18"	"18.00"	"3"	"5"	"cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00307, Pf00402"	"8407"	"ENSG00000158710"	"TAGLN2"	"E9KL39; hsa:8407; P37802; Q5JRQ6; Q5JRQ7; Q6FGI1; Q9BUH5; Q9H4P0"	""	"Platelet degranulation"	"1"	"0"	"101.0"	"66.5"	"176.3"	"259.6"	"117.2"	"100.4"	"154.0"	"165.4"	"200.5"	"719.1"	"2378.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78344"	"Eukaryotic translation initiation factor 4 gamma 2 OS=Homo sapiens OX=9606 GN=EIF4G2 PE=1 SV=1"	"0.000"	""	"6"	"4"	"10"	"4"	"907"	"102.3"	"7.14"	"1638.55"	"17.97"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"1982"	"ENSG00000110321"	"EIF4G2"	"hsa:1982; O60877; P78344; P78404; Q0VH00; Q0VH01; Q2NKW9; Q49A79; Q53EU1; Q58EZ2; Q8NI71; Q96C16"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation; Acute viral myocarditis"	"ISG15 antiviral mechanism"	"4"	"0"	"310.1"	"239.8"	"423.7"	"446.0"	"318.0"	"366.4"	"495.2"	"495.2"	"582.9"	"1039.9"	"1568.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15355"	"Protein phosphatase 1G OS=Homo sapiens OX=9606 GN=PPM1G PE=1 SV=1"	"0.000"	""	"10"	"4"	"9"	"4"	"546"	"59.2"	"4.36"	"1362.73"	"17.93"	"3"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00481"	"5496"	"ENSG00000115241"	"PPM1G"	"hsa:5496; O15355"	"VEGFA-VEGFR2 signaling; mRNA processing"	""	"2"	"0"	"273.8"	"239.4"	"331.7"	"429.6"	"266.0"	"236.3"	"394.7"	"419.6"	"497.5"	"859.9"	"1231.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52789"	"Hexokinase-2 OS=Homo sapiens OX=9606 GN=HK2 PE=1 SV=2"	"0.000"	""	"6"	"5"	"12"	"4"	"917"	"102.3"	"6.05"	"2075.64"	"17.90"	"5"	"5"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3099"	"ENSG00000159399"	"HK2"	"D6W5J2; hsa:3099; P52789; Q8WU87; Q9UN82"	"Clear cell renal cell carcinoma pathways; Warburg effect modulated by deubiquitinating enzymes and their substrates; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"Glycolysis"	"7"	"2"	"223.6"	"165.3"	"298.8"	"282.2"	"177.0"	"186.9"	"423.9"	"461.3"	"694.6"	"2021.3"	"2743.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53041"	"Serine/threonine-protein phosphatase 5 OS=Homo sapiens OX=9606 GN=PPP5C PE=1 SV=1"	"0.000"	""	"12"	"6"	"10"	"6"	"499"	"56.8"	"6.28"	"2042.09"	"17.82"	"5"	"5"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00149, Pf00515, Pf08321"	"5536"	"ENSG00000011485"	"PPP5C"	"hsa:5536; P53041; Q16722; Q53XV2"	"MAPK signaling pathway; ATM signaling in development and disease"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Negative regulation of MAPK pathway; ESR-mediated signaling"	"5"	"0"	"109.3"	"108.4"	"138.6"	"163.4"	"108.0"	"110.4"	"542.7"	"608.0"	"1170.8"	"4147.6"	"6060.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13243"	"Serine/arginine-rich splicing factor 5 OS=Homo sapiens OX=9606 GN=SRSF5 PE=1 SV=1"	"0.000"	""	"17"	"5"	"8"	"4"	"272"	"31.2"	"11.59"	"857.42"	"17.79"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076"	"6430"	"ENSG00000100650"	"SRSF5"	"hsa:6430; O14797; Q13243; Q16662; Q49AD6; Q6FGE0"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"6"	"0"	"479.9"	"430.9"	"472.6"	"571.8"	"392.4"	"409.2"	"606.5"	"621.2"	"738.7"	"1305.2"	"1879.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULP9"	"TBC1 domain family member 24 OS=Homo sapiens OX=9606 GN=TBC1D24 PE=1 SV=2"	"0.000"	""	"8"	"4"	"6"	"4"	"559"	"62.9"	"7.36"	"604.00"	"17.79"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf00566, Pf07534"	"57465"	"ENSG00000162065"	"TBC1D24"	"A0JNW3; B9A6M6; hsa:57465; Q2KJ08; Q9ULP9"	""	"TBC/RABGAPs"	"1"	"0"	"89.9"	"77.9"	"126.3"	"131.8"	"109.9"	"129.5"	"667.4"	"721.4"	"1224.0"	"2035.4"	"2149.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33240"	"Cleavage stimulation factor subunit 2 OS=Homo sapiens OX=9606 GN=CSTF2 PE=1 SV=1"	"0.000"	""	"14"	"5"	"9"	"5"	"577"	"60.9"	"6.83"	"1461.50"	"17.75"	"4"	"5"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076, Pf14304, Pf14327"	"1478"	"ENSG00000101811"	"CSTF2"	"hsa:1478; P33240; Q5H951; Q6LA74; Q8N502"	"mRNA processing"	"tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"6"	"0"	"302.2"	"248.9"	"335.3"	"414.9"	"292.5"	"297.6"	"411.7"	"433.5"	"513.5"	"1164.0"	"1669.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60841"	"Eukaryotic translation initiation factor 5B OS=Homo sapiens OX=9606 GN=EIF5B PE=1 SV=4"	"0.000"	""	"6"	"7"	"9"	"7"	"1220"	"138.7"	"5.49"	"3121.08"	"17.75"	"6"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03144, Pf11987"	"9669"	"ENSG00000158417"	"EIF5B"	"hsa:9669; O60841; O95805; Q53RV7; Q53SI8; Q9UF81; Q9UMN7"	"Translation factors; Ciliary landscape"	"GTP hydrolysis and joining of the 60S ribosomal subunit"	"3"	"0"	"438.4"	"292.1"	"478.7"	"543.0"	"402.4"	"428.0"	"835.3"	"894.0"	"1588.7"	"3261.6"	"3068.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08J23"	"RNA cytosine C(5)-methyltransferase NSUN2 OS=Homo sapiens OX=9606 GN=NSUN2 PE=1 SV=2"	"0.000"	""	"6"	"3"	"7"	"3"	"767"	"86.4"	"6.77"	"1766.43"	"17.74"	"2"	"3"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01189"	"54888"	"ENSG00000037474"	"NSUN2"	"A8K529; B2RNR4; B3KP09; B4DQW2; G3V1R4; hsa:54888; Q08J23; Q9BVN4; Q9H858; Q9NXD9"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"238.4"	"196.7"	"241.8"	"277.3"	"207.3"	"247.6"	"329.6"	"327.0"	"362.2"	"607.7"	"760.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60701"	"UDP-glucose 6-dehydrogenase OS=Homo sapiens OX=9606 GN=UGDH PE=1 SV=1"	"0.000"	""	"17"	"6"	"10"	"6"	"494"	"55.0"	"7.12"	"1684.70"	"17.72"	"5"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes"	"cytosol;nucleus"	"other molecular function"	"Pf00984, Pf03720, Pf03721"	"7358"	"ENSG00000109814"	"UGDH"	"B3KUU2; B4DN25; hsa:7358; O60589; O60701"	"UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Formation of the active cofactor, UDP-glucuronate"	"3"	"0"	"215.8"	"189.1"	"193.5"	"236.0"	"174.3"	"198.3"	"421.7"	"439.6"	"655.3"	"1785.9"	"2299.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY18"	"Structural maintenance of chromosomes protein 5 OS=Homo sapiens OX=9606 GN=SMC5 PE=1 SV=2"	"0.000"	""	"6"	"5"	"10"	"5"	"1101"	"128.7"	"8.38"	"1897.48"	"17.60"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02463"	"23137"	"ENSG00000198887"	"SMC5"	"A6NM81; hsa:23137; O60335; Q05D92; Q5VZ60; Q8IY18; Q96SB9"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"123.4"	"136.5"	"139.3"	"160.7"	"133.2"	"126.2"	"203.5"	"212.6"	"263.3"	"669.8"	"792.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92620"	"Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP16 OS=Homo sapiens OX=9606 GN=DHX38 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"1227"	"140.4"	"6.54"	"1962.40"	"17.56"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"9785"	"ENSG00000140829"	"DHX38"	"B4DVG8; D3DWS7; hsa:9785; O75212; Q92620; Q96HN7"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"5"	"0"	"89.3"	"68.0"	"124.9"	"111.5"	"85.7"	"88.3"	"152.1"	"130.0"	"200.2"	"452.2"	"555.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CQ4"	"Digestive organ expansion factor homolog OS=Homo sapiens OX=9606 GN=DIEXF PE=1 SV=2"	"0.000"	""	"7"	"6"	"13"	"6"	"756"	"87.0"	"5.88"	"2163.86"	"17.54"	"5"	"5"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf06862"	"27042"	"ENSG00000117597"	"UTP25"	"hsa:27042; O75992; Q4VY00; Q63HL9; Q68CQ4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"450.5"	"440.0"	"495.6"	"556.6"	"420.2"	"438.5"	"522.2"	"528.0"	"561.7"	"944.1"	"1422.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00567"	"Nucleolar protein 56 OS=Homo sapiens OX=9606 GN=NOP56 PE=1 SV=4"	"0.000"	""	"11"	"5"	"9"	"5"	"594"	"66.0"	"9.19"	"2277.83"	"17.53"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"10528"	"ENSG00000101361"	"NOP56"	"hsa:10528; O00567; Q2M3T6; Q9NQ05"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; Association of TriC/CCT with target proteins during biosynthesis"	"3"	"0"	"257.2"	"233.1"	"264.0"	"298.8"	"242.2"	"272.3"	"489.3"	"509.1"	"769.7"	"1012.7"	"1052.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94763"	"Unconventional prefoldin RPB5 interactor 1 OS=Homo sapiens OX=9606 GN=URI1 PE=1 SV=3"	"0.000"	""	"13"	"4"	"7"	"4"	"535"	"59.8"	"5.05"	"1347.56"	"17.44"	"3"	"4"	"other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02996"	"8725"	"ENSG00000105176"	"URI1"	"A8K805; H7BY42; hsa:8725; O94763; Q8TC23; Q9UNU3"	""	""	"0"	"0"	"54.1"	"47.0"	"63.7"	"83.1"	"61.0"	"63.7"	"108.3"	"142.5"	"189.9"	"626.3"	"855.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61964"	"WD repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=WDR5 PE=1 SV=1"	"0.000"	""	"17"	"5"	"10"	"5"	"334"	"36.6"	"8.27"	"1643.38"	"17.41"	"5"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400"	"11091"	"ENSG00000196363"	"WDR5"	"hsa:11091; P61964; Q91VA5; Q9NWX7; Q9UGP9"	"Pleural mesothelioma; Kleefstra syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Neddylation; Formation of WDR5-containing histone-modifying complexes; RMTs methylate histone arginines; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; HATs acetylate histones; Cardiogenesis"	"10"	"0"	"185.9"	"170.1"	"231.3"	"331.8"	"179.1"	"195.2"	"362.5"	"380.3"	"570.5"	"1634.6"	"2482.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TBB1"	"Ribonuclease H2 subunit B OS=Homo sapiens OX=9606 GN=RNASEH2B PE=1 SV=1"	"0.000"	""	"18"	"5"	"10"	"5"	"312"	"35.1"	"9.13"	"1873.71"	"17.40"	"4"	"4"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf09468, Pf17745"	"79621"	"ENSG00000136104"	"RNASEH2B"	"G3XAJ1; hsa:79621; Q05DR2; Q5TBB1; Q6PK48; Q9HAF7"	""	""	"0"	"0"	"333.7"	"301.2"	"358.2"	"416.7"	"310.1"	"324.0"	"883.4"	"939.4"	"1606.6"	"3947.6"	"4964.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMR2"	"ATP-dependent RNA helicase DDX19B OS=Homo sapiens OX=9606 GN=DDX19B PE=1 SV=1"	"0.000"	""	"14"	"5"	"9"	"1"	"479"	"53.9"	"6.30"	"1376.60"	"17.39"	"4"	"5"	"other metabolic processes;transport"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"11269"	"ENSG00000157349"	"DDX19B"	"B3KNE9; B4DXS6; E7EMK4; hsa:11269; Q6FIB7; Q6IAE0; Q96KE7; Q9H0U0; Q9UMR2"	""	""	"0"	"0"	"31.2"	"10.5"	"30.9"	"37.0"	"21.2"	"25.5"	"29.0"	"36.0"	"37.3"	"63.2"	"110.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22087"	"rRNA 2'-O-methyltransferase fibrillarin OS=Homo sapiens OX=9606 GN=FBL PE=1 SV=2"	"0.000"	""	"16"	"4"	"8"	"4"	"321"	"33.8"	"10.18"	"1742.99"	"17.38"	"4"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01269"	"2091"	"ENSG00000105202; ENSG00000280548"	"FBL"	"B5BUE8; hsa:2091; O75259; P22087; Q6IAT5; Q9UPI6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"225.8"	"198.1"	"230.6"	"272.4"	"203.7"	"207.0"	"304.9"	"303.9"	"406.0"	"806.0"	"1203.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49411"	"Elongation factor Tu, mitochondrial OS=Homo sapiens OX=9606 GN=TUFM PE=1 SV=2"	"0.000"	""	"12"	"5"	"11"	"5"	"452"	"49.5"	"7.61"	"2393.43"	"17.37"	"5"	"4"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"262.4"	"234.1"	"291.9"	"348.1"	"248.6"	"284.4"	"363.9"	"402.7"	"475.5"	"921.7"	"1378.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22392"	"Nucleoside diphosphate kinase B OS=Homo sapiens OX=9606 GN=NME2 PE=1 SV=1"	"0.000"	""	"41"	"5"	"10"	"2"	"152"	"17.3"	"8.41"	"2139.97"	"17.36"	"5"	"5"	"cell adhesion;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00334"	"4831; 654364"	"ENSG00000243678"	"NME2"	"A8MWA3; hsa:4831; hsa:654364; P22392; Q1WM23; Q6LCT6"	"Pyrimidine metabolism"	"Neutrophil degranulation; Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"5"	"3"	"303.3"	"292.6"	"404.1"	"734.9"	"237.0"	"284.1"	"515.1"	"554.7"	"711.7"	"1700.1"	"2609.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62913"	"60S ribosomal protein L11 OS=Homo sapiens OX=9606 GN=RPL11 PE=1 SV=2"	"0.000"	""	"21"	"4"	"9"	"4"	"178"	"20.2"	"9.60"	"1570.26"	"17.34"	"3"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00281, Pf00673"	"6135"	"ENSG00000142676"	"RPL11"	"hsa:6135; P25121; P39026; P62913; Q8TDH2; Q9Y674"	"Cytoplasmic ribosomal proteins"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"931.6"	"927.0"	"1018.7"	"1371.8"	"932.2"	"831.5"	"1340.3"	"1351.1"	"1546.2"	"2235.4"	"2344.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B4"	"Splicing factor 3B subunit 6 OS=Homo sapiens OX=9606 GN=SF3B6 PE=1 SV=1"	"0.000"	""	"34"	"4"	"9"	"4"	"125"	"14.6"	"9.38"	"1448.15"	"17.32"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"51639"	"ENSG00000115128"	"SF3B6"	"hsa:51639; Q53TM1; Q9Y3B4"	""	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"2"	"0"	"243.7"	"267.6"	"284.7"	"453.6"	"254.6"	"264.4"	"549.6"	"557.1"	"704.7"	"1698.1"	"2519.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB8"	"ATP-dependent RNA helicase SUPV3L1, mitochondrial OS=Homo sapiens OX=9606 GN=SUPV3L1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"6"	"2"	"786"	"87.9"	"7.99"	"1655.15"	"17.22"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00271, Pf12513, Pf18114, Pf18147"	"6832"	"ENSG00000156502"	"SUPV3L1"	"A8K301; hsa:6832; O43630; Q8IYB8"	""	""	"0"	"0"	"151.0"	"147.5"	"172.8"	"179.6"	"150.8"	"139.3"	"220.0"	"221.1"	"288.2"	"519.8"	"622.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2W4"	"Zinc finger CCCH-type antiviral protein 1 OS=Homo sapiens OX=9606 GN=ZC3HAV1 PE=1 SV=3"	"0.000"	""	"6"	"5"	"10"	"5"	"902"	"101.4"	"8.40"	"1889.22"	"17.19"	"5"	"5"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00644, Pf02825, Pf18606, Pf18633"	"56829"	"ENSG00000105939"	"ZC3HAV1"	"A4D1R2; A4D1S4; hsa:56829; Q7Z2W4; Q8IW57; Q8TAJ3; Q96N79; Q9H8R9; Q9P0Y7"	""	"Signaling by BRAF and RAF1 fusions"	"1"	"0"	"385.5"	"437.5"	"400.7"	"501.3"	"371.8"	"361.3"	"566.6"	"608.2"	"752.3"	"1651.4"	"2200.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55769"	"NHP2-like protein 1 OS=Homo sapiens OX=9606 GN=SNU13 PE=1 SV=3"	"0.000"	""	"54"	"5"	"8"	"5"	"128"	"14.2"	"8.46"	"1603.30"	"17.16"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01248"	"4809"	"ENSG00000100138"	"SNU13"	"hsa:4809; P55769"	"mRNA processing"	"mRNA Splicing - Major Pathway; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"4"	"0"	"237.7"	"270.8"	"287.0"	"425.4"	"200.3"	"188.1"	"540.3"	"607.6"	"960.2"	"1651.0"	"1679.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62979"	"Ubiquitin-40S ribosomal protein S27a OS=Homo sapiens OX=9606 GN=RPS27A PE=1 SV=2"	"0.000"	""	"44"	"6"	"8"	"6"	"156"	"18.0"	"9.64"	"1033.39"	"17.15"	"4"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;translational apparatus;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00240, Pf01599"	"6233"	"ENSG00000143947"	"RPS27A"	"hsa:6233; P02248; P02249; P02250; P14798; P62979; P62988; Q29120; Q6LBL4; Q6LDU5; Q8WYN8; Q91887; Q91888; Q9BQ77; Q9BWD6; Q9BX98; Q9UEF2; Q9UEG1; Q9UEK8; Q9UPK7"	"Cytoplasmic ribosomal proteins"	"Oxidative Stress Induced Senescence; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Orc1 removal from chromatin; Assembly of the pre-replicative complex; Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Separation of Sister Chromatids; Regulation of PLK1 Activity at G2/M Transition; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery; E3 ubiquitin ligases ubiquitinate target proteins; Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Stimuli-sensing channels; Amyloid fiber formation; Fanconi Anemia Pathway; Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; Aggrephagy; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Activated NOTCH1 Transmits Signal to the Nucleus; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus; Peroxisomal protein import; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Activation of IRF3, IRF7 mediated by TBK1, IKBKE; IKK complex recruitment mediated by RIP1; TRAF6-mediated induction of TAK1 complex within TLR4 complex; IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation; ER Quality Control Compartment (ERQC); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of TP53 Activity through Phosphorylation; Circadian Clock; Regulation of signaling by CBL; Metalloprotease DUBs; Regulation of necroptotic cell death; Oncogene Induced Senescence; Cyclin D associated events in G1; APC/C:Cdc20 mediated degradation of Cyclin B; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Negative regulation of FLT3; Downregulation of ERBB2:ERBB3 signaling; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Regulation of TP53 Activity through Methylation; Processing of DNA double-strand break ends; Regulation of BACH1 activity; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; Regulation of TNFR1 signaling; TNFR1-induced NF-kappa-B signaling pathway; MAP3K8 (TPL2)-dependent MAPK1/3 activation; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; Regulation of NF-kappa B signaling; Termination of translesion DNA synthesis; Negative regulators of DDX58/IFIH1 signaling; Prevention of phagosomal-lysosomal fusion; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; HDR through Homologous Recombination (HRR); Signaling by CSF1 (M-CSF) in myeloid cells; NOTCH1 Intracellular Domain Regulates Transcription; TICAM1-dependent activation of IRF3/IRF7; TICAM1,TRAF6-dependent induction of TAK1 complex; Glycogen synthesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Modulation by Mtb of host immune system; activated TAK1 mediates p38 MAPK activation; IRAK2 mediated activation of TAK1 complex; SARS-CoV-1 activates/modulates innate immune responses; Alpha-protein kinase 1 signaling pathway; Ovarian tumor domain proteases; Spry regulation of FGF signaling; RAS processing; PINK1-PRKN Mediated Mitophagy; Josephin domain DUBs; Regulation of FZD by ubiquitination; Chaperone Mediated Autophagy; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Formation of Incision Complex in GG-NER; Iron uptake and transport; Recognition of DNA damage by PCNA-containing replication complex; VLDLR internalisation and degradation; Myoclonic epilepsy of Lafora; DNA Damage Recognition in GG-NER; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Negative regulation of MAPK pathway; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); NRIF signals cell death from the nucleus; Assembly Of The HIV Virion; Dual Incision in GG-NER; Translesion Synthesis by POLH; Downregulation of ERBB4 signaling; Regulation of innate immune responses to cytosolic DNA; N-glycan trimming in the ER and Calnexin/Calreticulin cycle; Gap-filling DNA repair synthesis and ligation in GG-NER; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; Regulation of PTEN localization; Pexophagy; Maturation of protein E; Maturation of protein E; FLT3 signaling by CBL mutants; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"201"	"0"	"1098.5"	"1086.5"	"1288.8"	"1381.1"	"1069.4"	"997.0"	"1648.4"	"1739.5"	"1885.3"	"3469.2"	"5504.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5H9R7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PPP6R3 PE=1 SV=2"	"0.000"	""	"9"	"6"	"9"	"6"	"873"	"97.6"	"4.60"	"1482.65"	"17.10"	"4"	"5"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"55291"	"ENSG00000110075"	"PPP6R3"	"hsa:55291; Q3B7I1; Q3I4Y0; Q3KR35; Q5H9R7; Q68CR3; Q7L4R8; Q8N3B2; Q96MB2; Q9H2K5; Q9H2K6; Q9HCL4; Q9NUY3"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"165.4"	"128.1"	"232.6"	"228.1"	"182.1"	"168.1"	"275.6"	"229.2"	"329.5"	"600.2"	"786.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28340"	"DNA polymerase delta catalytic subunit OS=Homo sapiens OX=9606 GN=POLD1 PE=1 SV=2"	"0.000"	""	"7"	"7"	"10"	"7"	"1107"	"123.6"	"7.03"	"2287.58"	"17.07"	"5"	"5"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260"	"5424"	"ENSG00000062822"	"POLD1"	"hsa:5424; P28340; Q8NER3; Q96H98"	"Homologous recombination; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Progeria-associated lipodystrophy; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Cytosolic iron-sulfur cluster assembly; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"27"	"0"	"436.7"	"335.8"	"507.1"	"657.9"	"362.6"	"316.1"	"661.6"	"659.3"	"813.8"	"1920.0"	"2669.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21127"	"Cyclin-dependent kinase 11B OS=Homo sapiens OX=9606 GN=CDK11B PE=1 SV=4"	"0.000"	""	"9"	"5"	"8"	"5"	"795"	"92.6"	"5.54"	"1567.07"	"17.06"	"4"	"4"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"984"	"ENSG00000248333"	"CDK11B"	"B7ZVY7; hsa:984; J3KTL7; J3QR29; J3QR44; O95265; P21127; Q12817; Q12818; Q12819; Q12820; Q12822; Q8N530; Q9NZS5; Q9UBJ0; Q9UBQ1; Q9UBR0; Q9UNY2; Q9UP57; Q9UP58; Q9UP59"	"1p36 copy number variation syndrome"	"Recruitment of mitotic centrosome proteins and complexes"	"2"	"0"	"282.8"	"276.0"	"303.9"	"397.0"	"256.1"	"287.3"	"435.4"	"468.2"	"555.3"	"1043.2"	"1718.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96J02"	"E3 ubiquitin-protein ligase Itchy homolog OS=Homo sapiens OX=9606 GN=ITCH PE=1 SV=2"	"0.000"	""	"6"	"5"	"10"	"5"	"903"	"102.7"	"6.30"	"1546.62"	"17.06"	"4"	"5"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf00397, Pf00632"	"83737"	"ENSG00000078747"	"ITCH"	"A6NEW4; B4E234; E1P5P3; F5H217; hsa:83737; O43584; Q5QP37; Q5TEL0; Q96F66; Q96J02; Q9BY75; Q9H451; Q9H4U5"	"VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; 10q11.21q11.23 copy number variation syndrome; Notch signaling pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Degradation of GLI1 by the proteasome; Hedgehog 'on' state; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Activated NOTCH1 Transmits Signal to the Nucleus; Regulation of necroptotic cell death; NOD1/2 Signaling Pathway; Negative regulators of DDX58/IFIH1 signaling; SARS-CoV-1 activates/modulates innate immune responses; Downregulation of ERBB4 signaling"	"15"	"0"	"120.4"	"118.0"	"172.3"	"201.4"	"125.2"	"136.1"	"299.6"	"296.5"	"497.3"	"1785.7"	"2482.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P80723"	"Brain acid soluble protein 1 OS=Homo sapiens OX=9606 GN=BASP1 PE=1 SV=2"	"0.000"	""	"40"	"6"	"9"	"6"	"227"	"22.7"	"4.63"	"2095.43"	"17.05"	"4"	"4"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05466"	"10409"	"ENSG00000176788"	"BASP1"	"B4DJA8; D3DTD5; hsa:10409; O43596; P80723; Q5U0S0; Q9BWA5"	""	"RHOF GTPase cycle"	"1"	"0"	"381.2"	"281.8"	"490.6"	"532.5"	"313.3"	"357.9"	"655.7"	"680.3"	"984.4"	"3167.8"	"5394.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35249"	"Replication factor C subunit 4 OS=Homo sapiens OX=9606 GN=RFC4 PE=1 SV=2"	"0.000"	""	"21"	"5"	"8"	"5"	"363"	"39.7"	"8.02"	"1602.11"	"17.03"	"4"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5984"	"ENSG00000163918"	"RFC4"	"B4DM41; D3DNV2; hsa:5984; P35249; Q6FHX7"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Polymerase switching on the C-strand of the telomere; Polymerase switching; Activation of ATR in response to replication stress; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"28"	"0"	"400.8"	"371.5"	"421.6"	"518.8"	"342.1"	"404.1"	"613.8"	"650.4"	"891.8"	"2040.2"	"2610.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01085"	"Nucleolysin TIAR OS=Homo sapiens OX=9606 GN=TIAL1 PE=1 SV=1"	"0.000"	""	"12"	"5"	"11"	"4"	"375"	"41.6"	"7.74"	"2190.01"	"16.98"	"5"	"4"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7073"	"ENSG00000151923"	"TIAL1"	"A8K3T0; A8K4L9; hsa:7073; Q01085"	""	"FGFR2 alternative splicing"	"1"	"1"	"443.2"	"410.9"	"515.0"	"574.7"	"459.7"	"461.5"	"587.9"	"605.0"	"703.7"	"1056.1"	"1440.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L9B9"	"Endonuclease/exonuclease/phosphatase family domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EEPD1 PE=1 SV=2"	"0.000"	""	"8"	"4"	"7"	"4"	"569"	"62.4"	"8.41"	"1120.71"	"16.94"	"3"	"4"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes"	"nucleic acid binding activity"	"Pf12836"	"80820"	"ENSG00000122547"	"EEPD1"	"hsa:80820; Q7L9B9; Q96K64; Q9C0F7"	""	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux"	"1"	"0"	"70.4"	"52.8"	"85.7"	"99.5"	"77.0"	"81.1"	"197.3"	"214.7"	"329.5"	"924.8"	"1403.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW64"	"Pre-mRNA-splicing factor RBM22 OS=Homo sapiens OX=9606 GN=RBM22 PE=1 SV=1"	"0.000"	""	"15"	"6"	"12"	"6"	"420"	"46.9"	"8.54"	"2658.54"	"16.88"	"6"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55696"	"ENSG00000086589"	"RBM22"	"A6NDM5; B4DLI9; hsa:55696; O95607; Q9NW64"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"626.5"	"675.1"	"599.6"	"747.4"	"585.0"	"548.6"	"896.0"	"968.4"	"1126.9"	"2361.3"	"3152.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4J8"	"Dystrobrevin alpha OS=Homo sapiens OX=9606 GN=DTNA PE=1 SV=2"	"0.000"	""	"9"	"6"	"10"	"3"	"743"	"83.8"	"6.89"	"1940.46"	"16.85"	"5"	"5"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1837"	"ENSG00000134769"	"DTNA"	"A8K541; A8MSZ0; A8MUY4; B4DGS6; B4DIR0; B4DIU8; hsa:1837; M0QYX6; M0R397; O15332; O15333; O75697; Q13197; Q13198; Q13199; Q13498; Q13499; Q13500; Q59GK7; Q9BS59; Q9Y4J8"	"13q12.12 copy number variation"	""	"1"	"3"	"303.1"	"276.1"	"317.2"	"432.8"	"276.6"	"287.0"	"496.8"	"536.0"	"695.7"	"1473.6"	"1893.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35269"	"General transcription factor IIF subunit 1 OS=Homo sapiens OX=9606 GN=GTF2F1 PE=1 SV=2"	"0.000"	""	"13"	"6"	"10"	"6"	"517"	"58.2"	"7.49"	"2618.60"	"16.80"	"6"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf05793"	"2962"	"ENSG00000125651"	"GTF2F1"	"B2RCS0; hsa:2962; P35269; Q9BWN0"	""	"Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"32"	"0"	"324.5"	"289.4"	"369.2"	"446.8"	"328.4"	"340.7"	"467.2"	"482.2"	"548.1"	"1246.1"	"2293.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14561"	"Acyl carrier protein, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAB1 PE=1 SV=3"	"0.000"	""	"22"	"4"	"8"	"4"	"156"	"17.4"	"4.93"	"1447.98"	"16.78"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;nucleus"	"translation activity;other molecular function"	"Pf00550"	"4706"	"ENSG00000004779"	"NDUFAB1"	"B2R4M1; hsa:4706; O14561; Q9UNV1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Glyoxylate metabolism and glycine degradation; Mitochondrial Fatty Acid Beta-Oxidation; Complex I biogenesis"	"7"	"0"	"331.7"	"348.2"	"362.0"	"503.3"	"321.6"	"334.5"	"741.6"	"791.4"	"1122.8"	"3042.0"	"3795.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQG5"	"Regulation of nuclear pre-mRNA domain-containing protein 1B OS=Homo sapiens OX=9606 GN=RPRD1B PE=1 SV=1"	"0.000"	""	"18"	"7"	"13"	"4"	"326"	"36.9"	"5.97"	"3741.06"	"16.78"	"7"	"5"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818, Pf16566"	"58490"	"ENSG00000101413"	"RPRD1B"	"hsa:58490; Q1WDE7; Q6PKF4; Q9NQG5"	"Modulators of TCR signaling and T cell activation"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"237.6"	"206.4"	"261.7"	"377.4"	"195.1"	"209.9"	"419.8"	"451.9"	"644.2"	"2080.1"	"3026.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20248"	"Cyclin-A2 OS=Homo sapiens OX=9606 GN=CCNA2 PE=1 SV=2"	"0.000"	""	"12"	"3"	"5"	"3"	"432"	"48.5"	"6.54"	"1062.14"	"16.75"	"2"	"3"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00134, Pf02984, Pf16500"	"890"	"ENSG00000145386"	"CCNA2"	"A8K7B6; hsa:890; P20248; Q2M3U6; Q4W5P4; Q6LER8"	"AMP-activated protein kinase signaling; Cell cycle; Retinoblastoma gene in cancer; IL-18 signaling pathway"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; G2 Phase; Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Processing of DNA double-strand break ends; DNA Damage/Telomere Stress Induced Senescence; p53-Dependent G1 DNA Damage Response; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes"	"24"	"0"	"171.7"	"134.8"	"162.5"	"167.3"	"138.5"	"251.1"	"264.6"	"252.7"	"388.8"	"885.9"	"1214.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62633"	"Cellular nucleic acid-binding protein OS=Homo sapiens OX=9606 GN=CNBP PE=1 SV=1"	"0.000"	""	"25"	"3"	"5"	"3"	"177"	"19.5"	"7.71"	"489.75"	"16.72"	"1"	"3"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098"	"7555"	"ENSG00000169714"	"CNBP"	"A8K7V4; B2RAV9; B4DP17; D3DNB9; D3DNC0; D3DNC1; E9PDR7; hsa:7555; P20694; P62633; Q4JGY0; Q4JGY1; Q5QJR0; Q5U0E9; Q6PJI7; Q96NV3"	""	"SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"1"	"0"	"85.8"	"96.5"	"82.7"	"101.8"	"85.9"	"47.7"	"157.3"	"167.0"	"218.8"	"466.0"	"478.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16576"	"Histone-binding protein RBBP7 OS=Homo sapiens OX=9606 GN=RBBP7 PE=1 SV=1"	"0.000"	""	"15"	"8"	"13"	"2"	"425"	"47.8"	"5.05"	"2853.70"	"16.71"	"8"	"5"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12265"	"5931"	"ENSG00000102054"	"RBBP7"	"hsa:5931; Q16576; Q5JP00"	"Retinoblastoma gene in cancer; Interactome of polycomb repressive complex 2 (PRC2) ; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events; Deposition of new CENPA-containing nucleosomes at the centromere; Neddylation; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Potential therapeutics for SARS; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; HDACs deacetylate histones; RMTs methylate histone arginines; PKMTs methylate histone lysines; HATs acetylate histones; RNA Polymerase I Transcription Initiation; PRC2 methylates histones and DNA; Defective pyroptosis; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"20"	"0"	"159.3"	"188.4"	"156.6"	"212.2"	"145.6"	"158.7"	"255.7"	"279.1"	"346.3"	"760.3"	"998.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14CX7"	"N-alpha-acetyltransferase 25, NatB auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA25 PE=1 SV=1"	"0.000"	""	"10"	"6"	"9"	"6"	"972"	"112.2"	"6.64"	"1861.65"	"16.68"	"5"	"4"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf09797"	"80018"	"ENSG00000111300"	"NAA25"	"A0JLU7; hsa:80018; Q14CX7; Q6MZH1; Q7Z4N6; Q9H911"	""	""	"0"	"0"	"86.7"	"78.3"	"111.7"	"135.3"	"94.7"	"104.4"	"370.8"	"437.4"	"661.7"	"1295.3"	"1398.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12788"	"Transducin beta-like protein 3 OS=Homo sapiens OX=9606 GN=TBL3 PE=1 SV=2"	"0.000"	""	"7"	"4"	"10"	"4"	"808"	"89.0"	"6.90"	"1831.11"	"16.65"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00400, Pf08625"	"10607"	"ENSG00000183751"	"TBL3"	"hsa:10607; Q12788; Q59GD6; Q8IVB7; Q96A78"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"102.6"	"103.9"	"128.0"	"137.8"	"83.2"	"95.4"	"224.1"	"278.2"	"433.4"	"1153.1"	"1578.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14008"	"Cytoskeleton-associated protein 5 OS=Homo sapiens OX=9606 GN=CKAP5 PE=1 SV=3"	"0.000"	""	"3"	"5"	"9"	"5"	"2032"	"225.4"	"7.80"	"1761.84"	"16.63"	"4"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"9793"	"ENSG00000175216"	"CKAP5"	"hsa:9793; Q05D70; Q0VAX7; Q0VAX8; Q14008; Q14668; Q2TA89; Q6NSH4"	"4p16.3 copy number variation"	"Separation of Sister Chromatids; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases Activate Formins; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"14"	"0"	"357.2"	"317.9"	"383.2"	"429.1"	"375.2"	"385.0"	"513.7"	"532.5"	"667.8"	"1310.2"	"1663.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VN1"	"Vacuolar protein-sorting-associated protein 36 OS=Homo sapiens OX=9606 GN=VPS36 PE=1 SV=1"	"0.000"	""	"14"	"6"	"11"	"6"	"386"	"43.8"	"7.20"	"1892.09"	"16.61"	"6"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf04157, Pf11605"	"51028"	"ENSG00000136100"	"VPS36"	"A8K125; hsa:51028; Q3ZCV7; Q5H9S1; Q5VXB6; Q86VN1; Q9H8Z5; Q9Y3E3"	"Network map of SARS-CoV-2 signaling pathway"	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"3"	"0"	"150.4"	"133.3"	"211.7"	"248.7"	"212.0"	"292.2"	"797.0"	"839.0"	"1337.3"	"3246.1"	"3847.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6W5"	"Wiskott-Aldrich syndrome protein family member 2 OS=Homo sapiens OX=9606 GN=WASF2 PE=1 SV=3"	"0.000"	""	"9"	"3"	"8"	"2"	"498"	"54.3"	"5.53"	"1903.53"	"16.56"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10163"	"ENSG00000158195"	"WASF2"	"B4DZN0; hsa:10163; O60794; Q9UDY7; Q9Y6W5"	"Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"1"	"107.2"	"108.6"	"86.6"	"108.8"	"84.3"	"117.1"	"224.8"	"224.9"	"407.9"	"724.4"	"817.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63167"	"Dynein light chain 1, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL1 PE=1 SV=1"	"0.000"	""	"47"	"4"	"7"	"3"	"89"	"10.4"	"7.40"	"1103.55"	"16.56"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01221"	"8655"	"ENSG00000088986"	"DYNLL1"	"hsa:8655; P63167; Q15701"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); 3q29 copy number variation syndrome"	"HCMV Early Events; Neutrophil degranulation; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy; Separation of Sister Chromatids; Intraflagellar transport; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Macroautophagy; Activation of BIM and translocation to mitochondria"	"27"	"1"	"469.9"	"545.5"	"566.4"	"615.7"	"477.6"	"467.5"	"689.4"	"711.9"	"758.2"	"1557.4"	"1911.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15514"	"DNA-directed RNA polymerase II subunit RPB4 OS=Homo sapiens OX=9606 GN=POLR2D PE=1 SV=1"	"0.000"	""	"41"	"4"	"6"	"4"	"142"	"16.3"	"4.79"	"681.88"	"16.53"	"2"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf03874"	"5433"	"ENSG00000144231"	"POLR2D"	"hsa:5433; O15514; Q52LT4"	"Pyrimidine metabolism"	"Transcriptional regulation by small RNAs; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"42"	"0"	"292.3"	"273.2"	"306.3"	"344.2"	"290.5"	"270.4"	"355.0"	"367.8"	"395.2"	"499.8"	"565.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14927"	"Cytochrome b-c1 complex subunit 7 OS=Homo sapiens OX=9606 GN=UQCRB PE=1 SV=2"	"0.000"	""	"32"	"4"	"8"	"4"	"111"	"13.5"	"8.78"	"1654.56"	"16.52"	"4"	"4"	"other metabolic processes;transport"	"other membranes;mitochondrion"	""	"Pf02271"	"7381"	"ENSG00000156467"	"UQCRB"	"E5RJU0; hsa:7381; P14927; Q6FGD1"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"485.2"	"473.4"	"472.7"	"669.0"	"359.1"	"415.7"	"637.2"	"638.9"	"760.6"	"1043.9"	"1422.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6M0"	"Deubiquitinase OTUD6B OS=Homo sapiens OX=9606 GN=OTUD6B PE=1 SV=1"	"0.000"	""	"16"	"4"	"7"	"4"	"293"	"33.8"	"6.05"	"1129.89"	"16.47"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf02338"	"51633"	"ENSG00000155100"	"OTUD6B"	"A8K6I1; B4DEY0; hsa:51633; Q8N6M0; Q9NTA4; Q9Y387"	"Warburg effect modulated by deubiquitinating enzymes and their substrates"	""	"1"	"0"	"60.6"	"56.3"	"76.5"	"87.7"	"60.1"	"60.6"	"182.1"	"207.7"	"412.2"	"695.6"	"681.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTE3"	"Mini-chromosome maintenance complex-binding protein OS=Homo sapiens OX=9606 GN=MCMBP PE=1 SV=2"	"0.000"	""	"10"	"3"	"5"	"3"	"642"	"72.9"	"5.87"	"1047.48"	"16.47"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09739"	"79892"	"ENSG00000197771"	"MCMBP"	"B3KSP7; hsa:79892; Q6IA56; Q9BTE3; Q9BVT9; Q9H916"	""	""	"0"	"0"	"42.3"	"38.1"	"50.2"	"57.5"	"40.9"	"45.7"	"74.7"	"78.3"	"115.1"	"261.0"	"353.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13427"	"Peptidyl-prolyl cis-trans isomerase G OS=Homo sapiens OX=9606 GN=PPIG PE=1 SV=2"	"0.000"	""	"6"	"5"	"11"	"5"	"754"	"88.6"	"10.29"	"2066.20"	"16.42"	"5"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"9360"	"ENSG00000138398"	"PPIG"	"D3DPC5; D3DPC6; hsa:9360; O00706; Q13427; Q53R40; Q53SN4; Q96DG9"	""	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	"2"	"0"	"545.8"	"509.1"	"597.6"	"717.9"	"521.9"	"546.9"	"779.9"	"770.6"	"931.1"	"1877.9"	"2848.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62750"	"60S ribosomal protein L23a OS=Homo sapiens OX=9606 GN=RPL23A PE=1 SV=1"	"0.000"	""	"44"	"6"	"11"	"6"	"156"	"17.7"	"10.45"	"2449.52"	"16.41"	"6"	"5"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00276, Pf03939"	"6147"	"ENSG00000198242"	"RPL23A"	"B2R5B2; hsa:6147; P29316; P39024; P62750; Q92774"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"642.4"	"596.0"	"673.2"	"893.5"	"600.6"	"583.7"	"948.3"	"956.0"	"1177.6"	"1988.6"	"2805.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14241"	"Elongin-A OS=Homo sapiens OX=9606 GN=ELOA PE=1 SV=2"	"0.000"	""	"6"	"4"	"9"	"4"	"798"	"89.9"	"9.57"	"2091.45"	"16.39"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06881, Pf08711"	"6924"	"ENSG00000011007"	"ELOA"	"B2R7Q8; hsa:6924; Q14241; Q8IXH1"	"VEGFA-VEGFR2 signaling; 10q11.21q11.23 copy number variation syndrome"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation"	"13"	"0"	"211.9"	"182.2"	"217.2"	"277.2"	"211.0"	"249.8"	"714.0"	"796.9"	"1146.3"	"1221.3"	"1057.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2E4"	"Disco-interacting protein 2 homolog C OS=Homo sapiens OX=9606 GN=DIP2C PE=1 SV=2"	"0.000"	""	"4"	"4"	"6"	"4"	"1556"	"170.7"	"7.39"	"678.15"	"16.38"	"2"	"4"	""	""	""	"Pf00501, Pf06464"	"22982"	"ENSG00000151240"	"DIP2C"	"B4DPI5; hsa:22982; Q5SS78; Q9Y2E4"	""	""	"0"	"0"	"80.4"	"45.5"	"92.5"	"85.6"	"63.5"	"70.9"	"139.6"	"142.7"	"208.7"	"464.1"	"600.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35222"	"Catenin beta-1 OS=Homo sapiens OX=9606 GN=CTNNB1 PE=1 SV=1"	"0.000"	""	"6"	"5"	"9"	"4"	"781"	"85.4"	"5.86"	"1870.96"	"16.33"	"5"	"4"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"1499"	"ENSG00000168036"	"CTNNB1"	"A8K1L7; hsa:1499; P35222; Q8NEW9; Q8NI94; Q9H391"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Heart development; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Pathogenic Escherichia coli infection; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Gastric cancer network 2; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Endoderm differentiation; Ectoderm differentiation; Extracellular vesicle-mediated signaling in recipient cells; Focal adhesion; Ectoderm differentiation; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Embryonic stem cell pluripotency pathways; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; OSX and miRNAs in tooth development; Wnt signaling pathway and pluripotency; PTF1A related regulatory pathway; Wnt signaling in kidney disease; Endometrial cancer; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Ciliary landscape; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Gastrin signaling pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; Osteoblast differentiation and related diseases; TGF-beta receptor signaling in skeletal dysplasias; Genes controlling nephrogenesis; GDNF/RET signaling axis; Mammalian disorder of sexual development; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; 1q21.1 copy number variation syndrome; 7q11.23 copy number variation syndrome; Development of ureteric collection system; Pleural mesothelioma; Alzheimer's disease; Urotensin-II-mediated signaling pathway; Markers of kidney cell lineage; TROP2 regulatory signaling; 8p23.1 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response (only ATM dependent)"	"Somitogenesis; Deactivation of the beta-catenin transactivating complex; InlA-mediated entry of Listeria monocytogenes into host cells; RHO GTPases activate IQGAPs; Formation of paraxial mesoderm; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Formation of axial mesoderm; Myogenesis; Transcriptional Regulation by VENTX; Ca2+ pathway; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; Cardiogenesis; Germ layer formation at gastrulation; Formation of definitive endoderm; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; Binding of TCF/LEF:CTNNB1 to target gene promoters; RUNX3 regulates WNT signaling; Apoptotic cleavage of cell adhesion  proteins; LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production"	"96"	"1"	"363.8"	"420.2"	"490.2"	"535.0"	"334.8"	"334.0"	"580.5"	"591.7"	"659.9"	"1624.6"	"2334.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKL0"	"REST corepressor 1 OS=Homo sapiens OX=9606 GN=RCOR1 PE=1 SV=2"	"0.000"	""	"11"	"3"	"8"	"2"	"485"	"53.3"	"7.03"	"1646.26"	"16.32"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"23186"	"ENSG00000089902"	"RCOR1"	"hsa:23186; J3KN32; Q15044; Q6P2I9; Q86VG5; Q9UKL0"	""	"Regulation of PTEN gene transcription; Potential therapeutics for SARS; Factors involved in megakaryocyte development and platelet production; HDACs deacetylate histones"	"4"	"0"	"107.9"	"81.4"	"104.5"	"135.2"	"82.7"	"95.2"	"157.5"	"176.1"	"216.9"	"595.1"	"884.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75152"	"Zinc finger CCCH domain-containing protein 11A OS=Homo sapiens OX=9606 GN=ZC3H11A PE=1 SV=3"	"0.000"	""	"9"	"7"	"12"	"7"	"810"	"89.1"	"8.37"	"2468.48"	"16.31"	"7"	"5"	"other metabolic processes;transport"	"nucleus"	"other molecular function"	"Pf15663"	"9877"	"ENSG00000058673"	"ZC3H11A"	"hsa:9877; O75152; Q6AHY4; Q6AHY9; Q6AW79; Q6AWA1; Q6PJK4; Q86XZ7"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"761.7"	"651.5"	"861.6"	"1033.1"	"738.1"	"720.6"	"948.3"	"998.7"	"1070.4"	"1920.8"	"2580.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99986"	"Serine/threonine-protein kinase VRK1 OS=Homo sapiens OX=9606 GN=VRK1 PE=1 SV=1"	"0.000"	""	"19"	"6"	"9"	"6"	"396"	"45.4"	"8.91"	"1747.20"	"16.27"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus"	"kinase activity;other molecular function"	"Pf00069"	"7443"	"ENSG00000100749"	"VRK1"	"hsa:7443; Q3SYL2; Q99986"	""	"Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"2"	"0"	"987.5"	"945.3"	"1050.6"	"1343.6"	"909.4"	"929.8"	"1253.1"	"1163.2"	"1113.3"	"985.4"	"938.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14697"	"Neutral alpha-glucosidase AB OS=Homo sapiens OX=9606 GN=GANAB PE=1 SV=3"	"0.000"	""	"6"	"5"	"8"	"5"	"944"	"106.8"	"6.14"	"1155.33"	"16.27"	"3"	"5"	"protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf01055, Pf13802"	"23193"	"ENSG00000089597"	"GANAB"	"A6NC20; hsa:23193; Q14697; Q8WTS9; Q9P0X0"	"N-glycan biosynthesis"	"Maturation of spike protein; Calnexin/calreticulin cycle; Maturation of spike protein"	"5"	"0"	"280.1"	"232.1"	"304.1"	"455.5"	"260.8"	"255.1"	"447.8"	"438.1"	"570.4"	"924.6"	"996.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FN4"	"Copine-2 OS=Homo sapiens OX=9606 GN=CPNE2 PE=1 SV=3"	"0.000"	""	"11"	"4"	"7"	"4"	"548"	"61.2"	"6.07"	"1176.61"	"16.24"	"3"	"4"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf07002"	"221184"	"ENSG00000140848"	"CPNE2"	"hsa:221184; Q68D19; Q719H8; Q86XP9; Q96FN4"	""	""	"0"	"0"	"29.1"	"23.9"	"47.4"	"65.3"	"35.9"	"31.2"	"116.3"	"143.3"	"261.9"	"1664.6"	"2571.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43447"	"Peptidyl-prolyl cis-trans isomerase H OS=Homo sapiens OX=9606 GN=PPIH PE=1 SV=1"	"0.000"	""	"28"	"5"	"9"	"5"	"177"	"19.2"	"8.07"	"1593.08"	"16.23"	"4"	"5"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00160"	"10465"	"ENSG00000171960"	"PPIH"	"A6NNE7; hsa:10465; O43447"	""	"mRNA Splicing - Major Pathway; SARS-CoV-1 activates/modulates innate immune responses"	"2"	"0"	"596.5"	"607.6"	"689.9"	"1022.1"	"556.4"	"570.6"	"1055.6"	"1106.4"	"1244.5"	"2317.4"	"3309.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75955"	"Flotillin-1 OS=Homo sapiens OX=9606 GN=FLOT1 PE=1 SV=3"	"0.000"	""	"15"	"5"	"9"	"5"	"427"	"47.3"	"7.49"	"2106.22"	"16.17"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01145"	"10211"	"ENSG00000137312; ENSG00000206379; ENSG00000206480; ENSG00000230143; ENSG00000232280"	"FLOT1"	"B4DVY7; hsa:10211; O75955; Q969J8; Q9UHW1; Q9UNV8"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; Synaptic adhesion-like molecules"	"8"	"0"	"215.4"	"180.1"	"262.9"	"318.5"	"206.6"	"219.7"	"348.0"	"355.8"	"459.0"	"1018.8"	"1432.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50502"	"Hsc70-interacting protein OS=Homo sapiens OX=9606 GN=ST13 PE=1 SV=2"	"0.000"	""	"18"	"7"	"12"	"7"	"369"	"41.3"	"5.27"	"3001.02"	"16.16"	"7"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf17830, Pf18253"	"6767"	"ENSG00000100380"	"ST13"	"hsa:6767; O14999; P50502; Q2TU77"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"544.2"	"551.1"	"735.8"	"939.4"	"591.3"	"507.1"	"1026.8"	"1032.0"	"1227.2"	"1965.6"	"2211.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P016"	"Thymocyte nuclear protein 1 OS=Homo sapiens OX=9606 GN=THYN1 PE=1 SV=1"	"0.000"	""	"27"	"6"	"10"	"6"	"225"	"25.7"	"9.25"	"1881.48"	"16.12"	"5"	"5"	""	""	""	"Pf01878"	"29087"	"ENSG00000151500"	"THYN1"	"hsa:29087; Q567Q2; Q9H3L4; Q9HC20; Q9P016"	""	""	"0"	"0"	"401.4"	"445.6"	"464.1"	"529.9"	"475.3"	"440.4"	"646.4"	"667.0"	"849.8"	"1486.9"	"1635.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43427"	"Acidic fibroblast growth factor intracellular-binding protein OS=Homo sapiens OX=9606 GN=FIBP PE=1 SV=3"	"0.000"	""	"15"	"5"	"10"	"5"	"364"	"41.9"	"6.48"	"1825.82"	"16.09"	"5"	"5"	"signal transduction"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05427"	"9158"	"ENSG00000172500"	"FIBP"	"A8K0J7; hsa:9158; O43427; Q27Q85; Q6IBQ3; Q9HD65"	"Modulators of TCR signaling and T cell activation"	""	"1"	"0"	"111.1"	"93.8"	"136.0"	"161.9"	"133.5"	"202.5"	"646.6"	"765.1"	"1097.3"	"2117.2"	"2122.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15531"	"Nucleoside diphosphate kinase A OS=Homo sapiens OX=9606 GN=NME1 PE=1 SV=1"	"0.000"	""	"47"	"5"	"9"	"2"	"152"	"17.1"	"6.19"	"1483.19"	"16.07"	"4"	"5"	"DNA metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"translation activity;kinase activity;other molecular function"	"Pf00334"	"4830"	"ENSG00000239672"	"NME1"	"hsa:4830; P15531; Q6FGK3; Q86XQ2; Q9UDJ6"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates; Azathioprine ADME; Ribavirin ADME"	"4"	"0"	"37.7"	"39.4"	"66.4"	"112.4"	"32.7"	"47.6"	"89.4"	"93.7"	"126.6"	"394.2"	"516.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43809"	"Cleavage and polyadenylation specificity factor subunit 5 OS=Homo sapiens OX=9606 GN=NUDT21 PE=1 SV=1"	"0.000"	""	"26"	"7"	"12"	"7"	"227"	"26.2"	"8.82"	"2442.84"	"16.07"	"7"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13869"	"11051"	"ENSG00000167005"	"NUDT21"	"hsa:11051; O43809; Q6IB85; Q6NE84"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"999.5"	"1116.9"	"949.1"	"1329.6"	"870.0"	"868.5"	"1381.9"	"1384.5"	"1575.9"	"3548.3"	"5906.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZP0"	"Abl interactor 1 OS=Homo sapiens OX=9606 GN=ABI1 PE=1 SV=4"	"0.000"	""	"10"	"3"	"6"	"3"	"508"	"55.0"	"7.06"	"1668.95"	"16.07"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00018, Pf07815"	"10006"	"ENSG00000136754"	"ABI1"	"A9Z1Y6; B3KX62; B4DQ58; H7BXI6; hsa:10006; O15147; O76049; O95060; Q5T2R3; Q5T2R4; Q5T2R6; Q5T2R7; Q5T2R9; Q5W070; Q5W072; Q8IZP0; Q8TB63; Q96S81; Q9NXZ9; Q9NYB8"	"EGF/EGFR signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; VEGFA-VEGFR2 Pathway; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle"	"8"	"0"	"192.4"	"193.6"	"192.6"	"245.4"	"194.6"	"186.1"	"337.1"	"368.9"	"478.1"	"710.7"	"856.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46063"	"ATP-dependent DNA helicase Q1 OS=Homo sapiens OX=9606 GN=RECQL PE=1 SV=3"	"0.000"	""	"7"	"3"	"8"	"3"	"649"	"73.4"	"7.88"	"1757.67"	"16.01"	"3"	"3"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf16124"	"5965"	"ENSG00000004700"	"RECQL"	"A8K6G2; hsa:5965; P46063"	"Progeria-associated lipodystrophy"	""	"1"	"0"	"73.3"	"66.9"	"81.6"	"112.3"	"79.7"	"76.5"	"129.7"	"143.0"	"234.3"	"508.1"	"702.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57076"	"Cilia- and flagella-associated protein 298 OS=Homo sapiens OX=9606 GN=CFAP298 PE=1 SV=1"	"0.000"	""	"21"	"4"	"7"	"4"	"290"	"33.2"	"7.44"	"1362.02"	"16.00"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	""	"Pf11069"	"56683"	"ENSG00000159079"	"CFAP298"	"hsa:56683; P57076; Q53FH0"	"Ciliopathies"	""	"1"	"0"	"305.4"	"264.6"	"331.6"	"389.3"	"308.7"	"304.6"	"499.6"	"517.0"	"709.5"	"1363.8"	"1714.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62263"	"40S ribosomal protein S14 OS=Homo sapiens OX=9606 GN=RPS14 PE=1 SV=3"	"0.000"	""	"22"	"3"	"4"	"3"	"151"	"16.3"	"10.05"	"442.71"	"15.98"	"1"	"3"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00411"	"6208"	"ENSG00000164587"	"RPS14"	"B2R5G5; D3DQG5; hsa:6208; P06366; P62263; Q5BJI0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"87.6"	"90.5"	"107.1"	"132.1"	"83.5"	"85.9"	"152.1"	"148.2"	"199.6"	"464.8"	"600.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP8"	"Partner of Y14 and mago OS=Homo sapiens OX=9606 GN=PYM1 PE=1 SV=1"	"0.000"	""	"30"	"4"	"9"	"4"	"204"	"22.6"	"9.45"	"1646.05"	"15.98"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf09282"	"84305"	"ENSG00000170473"	"PYM1"	"B6ZDM5; hsa:84305; Q8IXJ8; Q8N8E7; Q9BRP8"	"TAR syndrome"	""	"1"	"0"	"187.1"	"181.9"	"193.6"	"214.8"	"178.5"	"184.3"	"272.3"	"281.5"	"364.1"	"622.9"	"673.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08579"	"U2 small nuclear ribonucleoprotein B'' OS=Homo sapiens OX=9606 GN=SNRPB2 PE=1 SV=1"	"0.000"	""	"10"	"3"	"12"	"1"	"225"	"25.5"	"9.72"	"1871.27"	"15.95"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"6629"	"ENSG00000125870"	"SNRPB2"	"B2R7J3; D3DW21; hsa:6629; P08579; Q9UJD4"	"mRNA processing; Ciliary landscape"	"mRNA Splicing - Major Pathway"	"3"	"0"	"457.4"	"287.1"	"449.8"	"567.1"	"371.0"	"369.7"	"475.2"	"462.0"	"484.0"	"792.0"	"1272.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H910"	"Jupiter microtubule associated homolog 2 OS=Homo sapiens OX=9606 GN=JPT2 PE=1 SV=1"	"0.000"	""	"24"	"3"	"8"	"3"	"190"	"20.1"	"9.26"	"1592.65"	"15.95"	"3"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf17054"	"90861"	"ENSG00000206053"	"JPT2"	"B1AJY2; B4DLH4; hsa:90861; Q6EIC7; Q9H910"	""	""	"0"	"0"	"79.8"	"69.0"	"95.9"	"123.5"	"86.4"	"73.8"	"130.6"	"138.5"	"181.3"	"430.3"	"572.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16698"	"2,4-dienoyl-CoA reductase, mitochondrial OS=Homo sapiens OX=9606 GN=DECR1 PE=1 SV=1"	"0.000"	""	"16"	"4"	"7"	"4"	"335"	"36.0"	"9.28"	"1131.00"	"15.92"	"3"	"4"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf13561"	"1666"	"ENSG00000104325"	"DECR1"	"B7Z6B8; hsa:1666; Q16698; Q2M304; Q93085"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; VEGFA-VEGFR2 signaling"	"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids"	"4"	"0"	"245.0"	"211.8"	"276.8"	"324.1"	"227.8"	"244.4"	"402.5"	"427.9"	"589.4"	"1386.8"	"2096.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TF01"	"Arginine/serine-rich protein PNISR OS=Homo sapiens OX=9606 GN=PNISR PE=1 SV=2"	"0.000"	""	"7"	"6"	"11"	"6"	"805"	"92.5"	"10.02"	"2258.53"	"15.92"	"6"	"5"	""	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf15996"	"25957"	"ENSG00000132424"	"PNISR"	"A8K540; E1P5D2; hsa:25957; Q5T064; Q5T065; Q6P2B4; Q6P2N4; Q6PJ93; Q6PK36; Q7Z640; Q8N2L1; Q8TF00; Q8TF01; Q96K10; Q96SI3; Q96SM5; Q9P076; Q9P0C0; Q9Y4N3"	""	""	"0"	"0"	"566.3"	"514.4"	"635.5"	"698.3"	"499.2"	"560.0"	"676.5"	"670.1"	"716.7"	"1054.1"	"1362.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14974"	"Protein phosphatase 1 regulatory subunit 12A OS=Homo sapiens OX=9606 GN=PPP1R12A PE=1 SV=1"	"0.000"	""	"7"	"5"	"8"	"5"	"1030"	"115.2"	"5.40"	"844.84"	"15.91"	"3"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00023, Pf15898"	"4659"	"ENSG00000058272"	"PPP1R12A"	"B4DZ09; F8VWB4; hsa:4659; O14974; Q2NKL4; Q569H0; Q86WU3; Q8NFR6; Q9BYH0"	"Focal adhesion; Hippo-Merlin signaling dysregulation; Regulation of actin cytoskeleton"	"Regulation of PLK1 Activity at G2/M Transition; RHO GTPases activate CIT; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"8"	"0"	"109.9"	"107.0"	"134.5"	"147.5"	"110.9"	"113.1"	"164.1"	"170.2"	"200.4"	"513.9"	"728.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50613"	"Cyclin-dependent kinase 7 OS=Homo sapiens OX=9606 GN=CDK7 PE=1 SV=1"	"0.000"	""	"16"	"4"	"7"	"4"	"346"	"39.0"	"8.47"	"1260.08"	"15.89"	"3"	"4"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1022"	"ENSG00000134058; ENSG00000277273"	"CDK7"	"hsa:1022; P50613; Q9BS60; Q9UE19"	"MicroRNAs in cardiomyocyte hypertrophy; Cell cycle; Cardiac hypertrophic response; Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"43"	"0"	"158.2"	"133.3"	"170.6"	"228.4"	"141.0"	"153.4"	"465.3"	"488.5"	"901.5"	"2288.5"	"3229.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49588"	"Alanine--tRNA ligase, cytoplasmic OS=Homo sapiens OX=9606 GN=AARS1 PE=1 SV=2"	"0.000"	""	"5"	"4"	"6"	"4"	"968"	"106.7"	"5.53"	"863.05"	"15.85"	"2"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf02272, Pf07973"	"16"	"ENSG00000090861"	"AARS1"	"A6NF14; B4DR45; hsa:16; P49588; Q53GV7; Q96FA0"	"IL-18 signaling pathway"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"176.7"	"115.8"	"204.4"	"255.0"	"145.6"	"180.9"	"267.2"	"231.4"	"289.3"	"1785.7"	"4005.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27816"	"Microtubule-associated protein 4 OS=Homo sapiens OX=9606 GN=MAP4 PE=1 SV=3"	"0.000"	""	"7"	"6"	"10"	"6"	"1152"	"120.9"	"5.43"	"2584.51"	"15.82"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00418"	"4134"	"ENSG00000047849"	"MAP4"	"hsa:4134; P27816; Q13082; Q59FT2; Q68D74; Q6ZUW9; Q86V26; Q96A76; Q96NS9"	"Splicing factor NOVA regulated synaptic proteins; 2q37 copy number variation syndrome"	""	"2"	"0"	"604.4"	"456.0"	"619.6"	"730.2"	"557.1"	"544.4"	"697.2"	"690.6"	"781.2"	"1203.7"	"1827.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60885"	"Bromodomain-containing protein 4 OS=Homo sapiens OX=9606 GN=BRD4 PE=1 SV=2"	"0.000"	""	"4"	"5"	"9"	"4"	"1362"	"152.1"	"9.19"	"1840.71"	"15.81"	"5"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00439, Pf17035, Pf17105"	"23476"	"ENSG00000141867"	"BRD4"	"hsa:23476; O60433; O60885; Q4G0X8; Q86YS8; Q96PD3"	"VEGFA-VEGFR2 signaling; 7q11.23 copy number variation syndrome"	"Potential therapeutics for SARS"	"3"	"1"	"261.6"	"227.1"	"277.4"	"332.8"	"268.8"	"260.6"	"428.3"	"458.5"	"648.8"	"1465.8"	"1870.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75821"	"Eukaryotic translation initiation factor 3 subunit G OS=Homo sapiens OX=9606 GN=EIF3G PE=1 SV=2"	"0.000"	""	"17"	"3"	"5"	"3"	"320"	"35.6"	"6.13"	"982.18"	"15.80"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12353"	"8666"	"ENSG00000130811"	"EIF3G"	"hsa:8666; O14801; O75821; Q969U5"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"72.6"	"77.2"	"82.0"	"115.9"	"70.7"	"66.5"	"116.0"	"123.2"	"161.9"	"463.1"	"926.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULV4"	"Coronin-1C OS=Homo sapiens OX=9606 GN=CORO1C PE=1 SV=1"	"0.000"	""	"16"	"9"	"15"	"9"	"474"	"53.2"	"7.08"	"3787.33"	"15.79"	"9"	"4"	"cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"23603"	"ENSG00000110880"	"CORO1C"	"A7MAP0; A7MAP1; B3KU12; hsa:23603; Q9NSK5; Q9ULV4"	""	""	"0"	"0"	"814.9"	"766.9"	"788.7"	"846.6"	"759.2"	"773.4"	"1096.0"	"1209.1"	"1530.9"	"3496.2"	"5057.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16658"	"Fascin OS=Homo sapiens OX=9606 GN=FSCN1 PE=1 SV=3"	"0.000"	""	"10"	"4"	"6"	"4"	"493"	"54.5"	"7.24"	"880.72"	"15.78"	"2"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf06268"	"6624"	"ENSG00000075618"	"FSCN1"	"A6NI89; B2RE97; hsa:6624; Q16658; Q96IC5; Q96IH1; Q9BRF1"	"VEGFA-VEGFR2 signaling; Urotensin-II-mediated signaling pathway"	"Interleukin-4 and Interleukin-13 signaling"	"3"	"0"	"122.7"	"132.5"	"120.8"	"155.5"	"101.9"	"101.8"	"154.9"	"199.7"	"235.1"	"912.6"	"2353.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULM3"	"YEATS domain-containing protein 2 OS=Homo sapiens OX=9606 GN=YEATS2 PE=1 SV=2"	"0.000"	""	"4"	"4"	"7"	"4"	"1422"	"150.7"	"8.98"	"1294.13"	"15.78"	"3"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03366"	"55689"	"ENSG00000163872"	"YEATS2"	"A7E2B9; D3DNS9; hsa:55689; Q641P6; Q9NW96; Q9ULM3"	""	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	"2"	"0"	"19.2"	"24.1"	"26.9"	"26.2"	"21.2"	"23.5"	"49.9"	"40.8"	"79.2"	"221.2"	"275.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50454"	"Serpin H1 OS=Homo sapiens OX=9606 GN=SERPINH1 PE=1 SV=2"	"0.000"	""	"11"	"3"	"5"	"3"	"418"	"46.4"	"8.69"	"903.34"	"15.72"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00079"	"871"	"ENSG00000149257"	"SERPINH1"	"B3KVJ3; hsa:871; P29043; P50454; Q5XPB4; Q6NSJ6; Q8IY96; Q9NP88"	"Endochondral ossification; Type I collagen synthesis in the context of osteogenesis imperfecta; Endochondral ossification with skeletal dysplasias; 15q13.3 copy number variation syndrome; 15q11q13 copy number variation"	"Collagen biosynthesis and modifying enzymes"	"6"	"0"	"117.4"	"116.4"	"141.0"	"135.7"	"106.3"	"126.9"	"184.0"	"208.7"	"243.6"	"539.2"	"692.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17980"	"26S proteasome regulatory subunit 6A OS=Homo sapiens OX=9606 GN=PSMC3 PE=1 SV=3"	"0.000"	""	"14"	"5"	"9"	"5"	"439"	"49.2"	"5.24"	"2414.17"	"15.70"	"5"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5702"	"ENSG00000165916"	"PSMC3"	"B2R8V1; hsa:5702; P17980; Q3B757; Q3B865; Q53HU5; Q6GPG8; Q6IBS1; Q96HD3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"244.3"	"218.0"	"268.3"	"314.3"	"211.5"	"243.8"	"363.0"	"333.5"	"405.4"	"749.8"	"1414.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSY1"	"BMP-2-inducible protein kinase OS=Homo sapiens OX=9606 GN=BMP2K PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1161"	"129.1"	"6.51"	"665.57"	"15.68"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf15282"	"55589"	"ENSG00000138756"	"BMP2K"	"hsa:55589; O94791; Q4W5H2; Q8IYF2; Q8N2G7; Q8NHG9; Q9NSY1; Q9NTG8"	""	""	"0"	"0"	"174.7"	"137.1"	"162.0"	"214.1"	"163.7"	"180.4"	"224.3"	"249.4"	"330.3"	"659.0"	"565.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33527"	"Multidrug resistance-associated protein 1 OS=Homo sapiens OX=9606 GN=ABCC1 PE=1 SV=3"	"0.000"	""	"5"	"4"	"6"	"4"	"1531"	"171.5"	"7.11"	"1011.17"	"15.67"	"2"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"4363"	"ENSG00000103222; ENSG00000278183"	"ABCC1"	"A3RJX2; C9JPJ4; hsa:4363; O14819; O43333; P33527; P78419; Q59GI9; Q9UQ97; Q9UQ99; Q9UQA0"	"Irinotecan pathway; Leukotriene metabolic pathway; TROP2 regulatory signaling"	"ABC-family proteins mediated transport; Paracetamol ADME; Cytoprotection by HMOX1; Transport of RCbl within the body; Heme degradation; Synthesis of Leukotrienes (LT) and Eoxins (EX)"	"9"	"0"	"59.6"	"30.9"	"69.4"	"85.4"	"51.1"	"48.1"	"119.2"	"131.3"	"241.0"	"577.1"	"738.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83916"	"Chromobox protein homolog 1 OS=Homo sapiens OX=9606 GN=CBX1 PE=1 SV=1"	"0.000"	""	"29"	"4"	"9"	"3"	"185"	"21.4"	"4.93"	"2178.39"	"15.67"	"4"	"3"	"cell organization and biogenesis;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf01393"	"10951"	"ENSG00000108468"	"CBX1"	"hsa:10951; P23197; P83916"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HCMV Early Events"	"2"	"0"	"416.0"	"394.3"	"392.6"	"580.7"	"334.0"	"332.5"	"495.5"	"531.8"	"616.9"	"1125.7"	"1579.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15287"	"RNA-binding protein with serine-rich domain 1 OS=Homo sapiens OX=9606 GN=RNPS1 PE=1 SV=1"	"0.000"	""	"13"	"4"	"10"	"4"	"305"	"34.2"	"11.84"	"2020.70"	"15.66"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10921"	"ENSG00000205937"	"RNPS1"	"A8K1P0; B4DDU8; B4DZU7; B7ZA17; hsa:10921; O75308; Q15287; Q32P25; Q8WY42; Q9NYG3"	"mRNA processing"	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"7"	"0"	"697.1"	"649.3"	"686.6"	"817.8"	"583.2"	"615.5"	"824.9"	"850.7"	"930.2"	"1706.0"	"2548.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30153"	"Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R1A PE=1 SV=4"	"0.000"	""	"9"	"6"	"11"	"6"	"589"	"65.3"	"5.11"	"2275.91"	"15.60"	"6"	"5"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02985"	"5518"	"ENSG00000105568"	"PPP2R1A"	"hsa:5518; P30153; Q13773; Q6ICQ3; Q96DH3"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; RAF activation; Negative regulation of MAPK pathway; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Cyclin D associated events in G1; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Cyclin A/B1/B2 associated events during G2/M transition; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Initiation of Nuclear Envelope (NE) Reformation; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"49"	"0"	"356.2"	"321.7"	"375.9"	"458.8"	"325.9"	"328.3"	"627.6"	"646.0"	"850.4"	"2060.9"	"2950.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2P0"	"Activity-dependent neuroprotector homeobox protein OS=Homo sapiens OX=9606 GN=ADNP PE=1 SV=1"	"0.000"	""	"4"	"4"	"7"	"4"	"1102"	"123.5"	"7.34"	"1232.71"	"15.60"	"3"	"4"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00046, Pf19627"	"23394"	"ENSG00000101126"	"ADNP"	"E1P5Y2; hsa:23394; O94881; Q5BKU2; Q9H2P0; Q9UG34"	""	""	"0"	"0"	"386.9"	"403.5"	"421.3"	"508.4"	"386.3"	"361.3"	"538.9"	"579.2"	"663.0"	"1436.0"	"2340.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y224"	"RNA transcription, translation and transport factor protein OS=Homo sapiens OX=9606 GN=RTRAF PE=1 SV=1"	"0.000"	""	"17"	"3"	"7"	"3"	"244"	"28.1"	"6.65"	"2023.67"	"15.59"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10036"	"51637"	"ENSG00000087302"	"RTRAF"	"hsa:51637; Q9Y224"	""	"tRNA processing in the nucleus"	"1"	"0"	"211.3"	"201.0"	"235.7"	"289.6"	"191.4"	"191.5"	"296.7"	"334.4"	"389.4"	"786.9"	"1053.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75534"	"Cold shock domain-containing protein E1 OS=Homo sapiens OX=9606 GN=CSDE1 PE=1 SV=2"	"0.000"	""	"6"	"5"	"10"	"5"	"798"	"88.8"	"6.25"	"1813.39"	"15.57"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf00313, Pf12901"	"7812"	"ENSG00000009307"	"CSDE1"	"A8K281; E9PGZ0; G5E9Q2; hsa:7812; O75534; O94961; Q5TF04; Q5TF05; Q68DF1; Q68DI9; Q9Y2S4"	""	""	"0"	"0"	"403.0"	"336.2"	"448.6"	"580.8"	"377.1"	"357.3"	"660.4"	"669.2"	"836.2"	"2309.3"	"4277.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TEA8"	"D-aminoacyl-tRNA deacylase 1 OS=Homo sapiens OX=9606 GN=DTD1 PE=1 SV=2"	""	""	"29"	"2"	"2"	"2"	"209"	"23.4"	"8.24"	""	"15.53"	""	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02580"	"92675"	"ENSG00000125821"	"DTD1"	"A8K5X5; D3DW37; hsa:92675; Q496D1; Q5W184; Q8TEA8; Q8WXU8; Q9BW67; Q9H464; Q9H474"	""	""	"0"	"0"	"20.3"	"21.6"	"17.7"	"20.7"	"15.2"	"17.6"	"49.9"	"63.0"	"96.2"	"258.6"	"254.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWB6"	"Arginine and glutamate-rich protein 1 OS=Homo sapiens OX=9606 GN=ARGLU1 PE=1 SV=1"	"0.000"	""	"15"	"5"	"9"	"5"	"273"	"33.2"	"10.35"	"1367.39"	"15.53"	"4"	"5"	""	"cytosol;mitochondrion;nucleus"	""	"Pf15346"	"55082"	"ENSG00000134884"	"ARGLU1"	"B4E0Y3; hsa:55082; Q5T257; Q6IQ34; Q9NWB6"	""	""	"0"	"0"	"711.4"	"576.3"	"776.5"	"993.7"	"652.2"	"650.7"	"1111.8"	"1130.0"	"1479.8"	"2488.5"	"2995.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51858"	"Hepatoma-derived growth factor OS=Homo sapiens OX=9606 GN=HDGF PE=1 SV=1"	"0.000"	""	"21"	"4"	"6"	"4"	"240"	"26.8"	"4.73"	"924.24"	"15.51"	"2"	"4"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00855"	"3068"	"ENSG00000143321"	"HDGF"	"B3KU21; D3DVC9; hsa:3068; P51858; Q5SZ07; Q5SZ08; Q5SZ09"	"IL-18 signaling pathway"	"XBP1(S) activates chaperone genes"	"2"	"0"	"166.8"	"142.2"	"221.0"	"295.3"	"148.2"	"137.8"	"255.7"	"260.6"	"316.7"	"929.3"	"2751.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00341"	"Vigilin OS=Homo sapiens OX=9606 GN=HDLBP PE=1 SV=2"	"0.000"	""	"4"	"4"	"8"	"4"	"1268"	"141.4"	"6.87"	"1556.31"	"15.48"	"4"	"4"	"other metabolic processes;transport"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013"	"3069"	"ENSG00000115677"	"HDLBP"	"B4DTQ2; E7EM71; hsa:3069; Q00341; Q53QU2; Q9UCY3"	"2q37 copy number variation syndrome"	"HDL clearance"	"2"	"0"	"211.5"	"179.7"	"249.1"	"321.8"	"208.2"	"222.5"	"354.3"	"361.6"	"509.8"	"1279.1"	"1906.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z417"	"Nuclear fragile X mental retardation-interacting protein 2 OS=Homo sapiens OX=9606 GN=NUFIP2 PE=1 SV=1"	"0.000"	""	"10"	"4"	"6"	"4"	"695"	"76.1"	"8.70"	"752.79"	"15.47"	"2"	"4"	""	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf15293"	"57532"	"ENSG00000108256"	"NUFIP2"	"A1L3A6; A1L3A7; hsa:57532; Q7Z417; Q9P2M5"	""	""	"0"	"0"	"279.7"	"212.6"	"284.4"	"296.2"	"241.3"	"243.7"	"335.8"	"358.6"	"439.3"	"630.2"	"781.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P6C2"	"RNA demethylase ALKBH5 OS=Homo sapiens OX=9606 GN=ALKBH5 PE=1 SV=2"	"0.000"	""	"15"	"3"	"5"	"3"	"394"	"44.2"	"9.09"	"1097.78"	"15.46"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf13532"	"54890"	"ENSG00000091542"	"ALKBH5"	"B4DVJ4; D3DXC6; hsa:54890; Q6P6C2; Q9NXD6"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Reversal of alkylation damage by DNA dioxygenases"	"2"	"0"	"249.9"	"242.5"	"228.2"	"307.7"	"249.0"	"214.1"	"317.0"	"324.2"	"350.6"	"503.2"	"514.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y606"	"tRNA pseudouridine synthase A OS=Homo sapiens OX=9606 GN=PUS1 PE=1 SV=3"	"0.000"	""	"14"	"4"	"8"	"4"	"427"	"47.4"	"8.41"	"1474.52"	"15.43"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01416"	"80324"	"ENSG00000177192"	"PUS1"	"A8K877; B3KQC1; hsa:80324; Q8WYT2; Q9BU44; Q9Y606"	""	""	"0"	"0"	"129.7"	"104.1"	"158.0"	"182.7"	"130.4"	"148.6"	"249.0"	"254.6"	"395.9"	"750.8"	"792.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNP9"	"Peptidyl-prolyl cis-trans isomerase E OS=Homo sapiens OX=9606 GN=PPIE PE=1 SV=1"	"0.000"	""	"12"	"3"	"8"	"2"	"301"	"33.4"	"5.60"	"1673.06"	"15.41"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00160"	"10450"	"ENSG00000084072"	"PPIE"	"B2R971; hsa:10450; O43634; O43635; Q32Q72; Q3S611; Q5TGA0; Q5TGA2; Q5TGA3; Q9UIZ5; Q9UNP9"	""	"mRNA Splicing - Major Pathway; Neutrophil degranulation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"6"	"0"	"92.9"	"80.6"	"96.8"	"132.4"	"96.3"	"97.4"	"139.3"	"145.4"	"161.0"	"420.1"	"834.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82650"	"28S ribosomal protein S22, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS22 PE=1 SV=1"	"0.000"	""	"15"	"5"	"11"	"5"	"360"	"41.3"	"7.90"	"2232.76"	"15.39"	"5"	"4"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10245"	"56945"	"ENSG00000175110"	"MRPS22"	"hsa:56945; P82650; Q9H3I1"	"Primary ovarian insufficiency"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"232.6"	"224.0"	"293.0"	"330.7"	"232.6"	"210.6"	"360.2"	"353.1"	"418.0"	"778.9"	"1189.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6SPF0"	"Atherin OS=Homo sapiens OX=9606 GN=SAMD1 PE=1 SV=1"	"0.000"	""	"8"	"3"	"7"	"3"	"538"	"56.0"	"7.58"	"850.72"	"15.39"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"other molecular function"	"Pf00536"	"90378"	"ENSG00000288488"	"SAMD1"	"hsa:90378; Q6P0R3; Q6PIS7; Q6SPF0; Q96IM4"	""	""	"0"	"0"	"353.0"	"311.0"	"345.3"	"444.0"	"300.7"	"337.8"	"433.7"	"456.4"	"494.7"	"809.0"	"1101.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36954"	"DNA-directed RNA polymerase II subunit RPB9 OS=Homo sapiens OX=9606 GN=POLR2I PE=1 SV=1"	"0.000"	""	"42"	"4"	"6"	"4"	"125"	"14.5"	"5.14"	"626.47"	"15.36"	"2"	"4"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096, Pf02150"	"5438"	"ENSG00000105258"	"POLR2I"	"B2R5J2; hsa:5438; P36954; Q6NW05"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"mRNA Splicing - Major Pathway; Transcriptional regulation by small RNAs; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; Inhibition of DNA recombination at telomere; PIWI-interacting RNA (piRNA) biogenesis; Processing of Capped Intron-Containing Pre-mRNA; Viral Messenger RNA Synthesis; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; MicroRNA (miRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM"	"43"	"0"	"257.9"	"300.6"	"262.8"	"324.1"	"253.0"	"197.0"	"353.6"	"359.7"	"381.6"	"527.6"	"677.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZT9"	"Egl nine homolog 1 OS=Homo sapiens OX=9606 GN=EGLN1 PE=1 SV=1"	"0.000"	""	"12"	"3"	"5"	"3"	"426"	"46.0"	"8.53"	"783.90"	"15.36"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01753, Pf13640"	"54583"	"ENSG00000135766"	"EGLN1"	"hsa:54583; Q8N3M8; Q9BZS8; Q9BZT0; Q9GZT9"	"Photodynamic therapy-induced HIF-1 survival signaling; Type 2 papillary renal cell carcinoma; Markers of kidney cell lineage"	"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"4"	"0"	"177.8"	"159.1"	"200.4"	"197.4"	"183.5"	"154.6"	"266.2"	"296.8"	"365.5"	"609.9"	"752.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19367"	"Hexokinase-1 OS=Homo sapiens OX=9606 GN=HK1 PE=1 SV=3"	"0.000"	""	"7"	"5"	"11"	"4"	"917"	"102.4"	"6.80"	"2680.33"	"15.36"	"5"	"4"	"other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"kinase activity;other molecular function"	"Pf00349, Pf03727"	"3098"	"ENSG00000156515"	"HK1"	"E9PCK0; hsa:3098; O43443; O43444; O75574; P19367; Q5VTC3; Q96HC8; Q9NNZ4; Q9NNZ5"	"Cori cycle; Photodynamic therapy-induced HIF-1 survival signaling; Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Disorders of fructose metabolism; Glucose metabolism in triple-negative breast cancer cells; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts; Glucuronidation"	"Glycolysis; Defective HK1 causes hexokinase deficiency (HK deficiency)"	"12"	"0"	"205.6"	"179.4"	"257.1"	"281.0"	"185.5"	"192.9"	"396.6"	"394.9"	"645.4"	"2372.5"	"3239.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBB9"	"Tuftelin-interacting protein 11 OS=Homo sapiens OX=9606 GN=TFIP11 PE=1 SV=1"	"0.000"	""	"6"	"4"	"8"	"4"	"837"	"96.8"	"5.67"	"1612.45"	"15.36"	"4"	"4"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"extracellular matrix;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01585, Pf07842, Pf12457"	"24144"	"ENSG00000100109"	"TFIP11"	"hsa:24144; O95908; Q20WL0; Q5H8V8; Q9UBB9; Q9UGV7; Q9Y2Q8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"167.6"	"133.4"	"223.2"	"233.5"	"160.4"	"165.7"	"279.4"	"292.1"	"422.8"	"1011.1"	"1716.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30566"	"Adenylosuccinate lyase OS=Homo sapiens OX=9606 GN=ADSL PE=1 SV=2"	"0.000"	""	"13"	"3"	"5"	"3"	"484"	"54.9"	"7.11"	"748.60"	"15.33"	"2"	"3"	"other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00206, Pf10397"	"158"	"ENSG00000239900"	"ADSL"	"B0QY76; hsa:158; O75495; P30566; Q5TI34"	""	"Purine ribonucleoside monophosphate biosynthesis"	"1"	"0"	"85.8"	"78.9"	"93.9"	"103.6"	"77.9"	"92.9"	"130.5"	"127.4"	"159.8"	"315.4"	"435.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92599"	"Septin-8 OS=Homo sapiens OX=9606 GN=SEPTIN8 PE=1 SV=4"	"0.000"	""	"7"	"4"	"11"	"1"	"483"	"55.7"	"6.28"	"1907.59"	"15.32"	"4"	"3"	"cell cycle OR cell proliferation;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00735"	"23176"	"ENSG00000164402"	"SEPTIN8"	"A6NC65; A6NKP6; F6W7K9; hsa:23176; Q8IX36; Q8IX37; Q92599; Q9BVB3"	"22q11.2 copy number variation syndrome"	""	"1"	"0"	"68.9"	"56.4"	"74.8"	"95.5"	"60.3"	"55.5"	"139.6"	"152.4"	"237.6"	"452.3"	"604.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15691"	"Microtubule-associated protein RP/EB family member 1 OS=Homo sapiens OX=9606 GN=MAPRE1 PE=1 SV=3"	"0.000"	""	"22"	"4"	"6"	"4"	"268"	"30.0"	"5.14"	"1222.88"	"15.31"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22919"	"ENSG00000101367"	"MAPRE1"	"B2R6I7; E1P5M8; hsa:22919; Q15691; Q3KQS8"	"Microtubule cytoskeleton regulation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; The role of GTSE1 in G2/M progression after G2 checkpoint"	"15"	"0"	"111.1"	"114.2"	"132.8"	"175.9"	"97.1"	"124.4"	"197.2"	"194.8"	"268.4"	"792.7"	"2974.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3E1"	"Hepatoma-derived growth factor-related protein 3 OS=Homo sapiens OX=9606 GN=HDGFL3 PE=1 SV=1"	"0.000"	""	"30"	"4"	"7"	"4"	"203"	"22.6"	"7.99"	"1313.39"	"15.29"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00855"	"50810"	"ENSG00000166503"	"HDGFL3"	"hsa:50810; Q9Y3E1"	""	""	"0"	"0"	"221.9"	"201.5"	"244.6"	"285.8"	"193.6"	"211.7"	"538.7"	"556.2"	"1035.4"	"2147.1"	"1908.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09497"	"Clathrin light chain B OS=Homo sapiens OX=9606 GN=CLTB PE=1 SV=1"	"0.000"	""	"18"	"4"	"8"	"4"	"229"	"25.2"	"4.64"	"1637.22"	"15.29"	"4"	"4"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01086"	"1212"	"ENSG00000175416"	"CLTB"	"hsa:1212; P09497; Q53Y37; Q6FHW1"	"Ebola virus infection in host; Fragile X syndrome; 5q35 copy number variation"	"Lysosome Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; Formation of annular gap junctions"	"11"	"0"	"498.6"	"446.1"	"489.1"	"564.6"	"425.5"	"426.8"	"528.9"	"570.0"	"618.3"	"794.1"	"1000.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14257"	"Reticulocalbin-2 OS=Homo sapiens OX=9606 GN=RCN2 PE=1 SV=1"	"0.000"	""	"11"	"2"	"6"	"2"	"317"	"36.9"	"4.40"	"1617.04"	"15.28"	"2"	"2"	""	"ER/Golgi;nucleus"	"other molecular function"	"Pf13202"	"5955"	"ENSG00000117906"	"RCN2"	"A8MTG6; F8WCY5; hsa:5955; Q14257; Q53XN8"	""	""	"0"	"0"	"343.0"	"272.0"	"299.4"	"293.2"	"258.2"	"278.8"	"336.7"	"346.3"	"389.1"	"618.9"	"747.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22570"	"NADPH:adrenodoxin oxidoreductase, mitochondrial OS=Homo sapiens OX=9606 GN=FDXR PE=1 SV=3"	"0.000"	""	"17"	"6"	"9"	"6"	"491"	"53.8"	"8.44"	"1068.36"	"15.28"	"4"	"5"	"other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf07992"	"2232"	"ENSG00000161513"	"FDXR"	"B4DDI7; B4DHX5; B4DQQ4; B4DX24; B7Z7G2; E7EQC1; hsa:2232; P22570; Q13716; Q4PJI0; Q9BU12"	"Iron-sulfur cluster biogenesis"	"Endogenous sterols; Pregnenolone biosynthesis; Defective CYP11A1 causes AICSR; Electron transport from NADPH to Ferredoxin"	"5"	"0"	"98.8"	"81.0"	"112.4"	"152.9"	"102.0"	"96.8"	"196.9"	"200.1"	"380.4"	"1129.7"	"1451.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JM3"	"Chromosome alignment-maintaining phosphoprotein 1 OS=Homo sapiens OX=9606 GN=CHAMP1 PE=1 SV=2"	"0.000"	""	"6"	"4"	"8"	"4"	"812"	"89.0"	"8.44"	"1714.50"	"15.27"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"283489"	"ENSG00000198824"	"CHAMP1"	"B3KU06; hsa:283489; Q6P181; Q8NC88; Q96JM3; Q9BST0"	""	""	"0"	"0"	"476.3"	"344.3"	"413.0"	"460.1"	"331.3"	"347.4"	"504.0"	"485.2"	"627.6"	"1164.4"	"1177.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2NKX8"	"DNA excision repair protein ERCC-6-like OS=Homo sapiens OX=9606 GN=ERCC6L PE=1 SV=1"	"0.000"	""	"4"	"4"	"8"	"4"	"1250"	"141.0"	"5.31"	"1491.29"	"15.23"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"54821"	"ENSG00000186871"	"ERCC6L"	"hsa:54821; Q2NKX8; Q8NCI1; Q96H93; Q9NXQ8"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"128.0"	"114.7"	"143.5"	"180.6"	"134.5"	"114.7"	"215.3"	"212.3"	"272.1"	"651.5"	"951.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY8"	"Corrinoid adenosyltransferase OS=Homo sapiens OX=9606 GN=MMAB PE=1 SV=1"	"0.000"	""	"16"	"3"	"8"	"3"	"250"	"27.4"	"8.60"	"1758.24"	"15.21"	"3"	"3"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf01923"	"326625"	"ENSG00000139428"	"MMAB"	"C5HU05; hsa:326625; Q96EY8; Q9BSH0"	"Vitamin B12 metabolism"	"Cobalamin (Cbl) metabolism; Defective MMAB causes MMA, cblB type"	"3"	"0"	"196.5"	"149.4"	"187.4"	"235.9"	"167.3"	"170.5"	"445.1"	"481.9"	"885.9"	"2070.5"	"2210.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IBS0"	"Twinfilin-2 OS=Homo sapiens OX=9606 GN=TWF2 PE=1 SV=2"	"0.000"	""	"13"	"3"	"5"	"2"	"349"	"39.5"	"6.84"	"812.31"	"15.19"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"11344"	"ENSG00000247596"	"TWF2"	"hsa:11344; Q6IBS0; Q9Y3F5"	""	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"2"	"0"	"44.4"	"33.9"	"45.0"	"70.5"	"45.8"	"39.3"	"118.7"	"141.7"	"273.7"	"814.9"	"896.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25786"	"Proteasome subunit alpha type-1 OS=Homo sapiens OX=9606 GN=PSMA1 PE=1 SV=1"	"0.000"	""	"18"	"3"	"5"	"3"	"263"	"29.5"	"6.61"	"667.21"	"15.16"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5682"	"ENSG00000129084"	"PSMA1"	"A8K400; hsa:5682; P25786; Q53YE8; Q9BRV9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"ER-Phagosome pathway; Ub-specific processing proteases; MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"217.4"	"165.1"	"256.2"	"298.0"	"202.9"	"212.7"	"290.1"	"272.2"	"292.7"	"659.3"	"1623.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52298"	"Nuclear cap-binding protein subunit 2 OS=Homo sapiens OX=9606 GN=NCBP2 PE=1 SV=1"	"0.000"	""	"44"	"5"	"8"	"5"	"156"	"18.0"	"8.21"	"1445.36"	"15.15"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"22916"	"ENSG00000114503"	"NCBP2"	"B2RE91; B4DMK7; E9PAR5; hsa:22916; P52298; Q14924; Q2TS50"	"mRNA processing; 3q29 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; mRNA Capping; mRNA Splicing - Major Pathway; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"234.1"	"213.8"	"269.1"	"395.8"	"257.7"	"250.1"	"384.1"	"415.9"	"513.7"	"1143.7"	"1586.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UII2"	"ATPase inhibitor, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5IF1 PE=1 SV=1"	"0.000"	""	"33"	"5"	"10"	"5"	"106"	"12.2"	"9.35"	"1864.00"	"15.12"	"4"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04568"	"93974"	"ENSG00000130770; ENSG00000285390"	"ATP5IF1"	"hsa:93974; Q5JXL8; Q6IAQ7; Q9BSL9; Q9UII2"	"Electron transport chain: OXPHOS system in mitochondria"	""	"1"	"0"	"919.5"	"746.1"	"858.3"	"895.3"	"712.0"	"796.8"	"1165.9"	"1136.7"	"1453.4"	"2946.9"	"3465.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23919"	"Thymidylate kinase OS=Homo sapiens OX=9606 GN=DTYMK PE=1 SV=4"	"0.000"	""	"21"	"5"	"9"	"5"	"212"	"23.8"	"8.27"	"1432.18"	"15.05"	"4"	"5"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf02223"	"1841"	"ENSG00000168393"	"DTYMK"	"B7ZW70; hsa:1841; P23919; Q6FGX1; Q9BUX4"	"Pyrimidine metabolism; 2q37 copy number variation syndrome"	"Interconversion of nucleotide di- and triphosphates"	"3"	"0"	"229.5"	"193.4"	"237.7"	"292.2"	"220.1"	"212.7"	"416.7"	"438.7"	"676.5"	"1704.8"	"2120.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFH3"	"Nucleoporin Nup43 OS=Homo sapiens OX=9606 GN=NUP43 PE=1 SV=1"	"0.000"	""	"9"	"3"	"8"	"3"	"380"	"42.1"	"5.63"	"1583.56"	"14.99"	"3"	"3"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"348995"	"ENSG00000120253"	"NUP43"	"B4E2F0; hsa:348995; Q8NFH3; Q9H8S0"	""	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Transport of Mature mRNA derived from an Intron-Containing Transcript; tRNA processing in the nucleus; HCMV Late Events; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); SARS-CoV-2 activates/modulates innate and adaptive immune responses; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Postmitotic nuclear pore complex (NPC) reformation"	"35"	"0"	"175.0"	"133.2"	"229.7"	"239.2"	"161.3"	"157.2"	"256.1"	"261.1"	"298.3"	"421.5"	"541.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NBJ5"	"Procollagen galactosyltransferase 1 OS=Homo sapiens OX=9606 GN=COLGALT1 PE=1 SV=1"	"0.000"	""	"12"	"6"	"10"	"6"	"622"	"71.6"	"7.31"	"2052.39"	"14.98"	"5"	"4"	"cell organization and biogenesis;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf01755, Pf13704"	"79709"	"ENSG00000130309"	"COLGALT1"	"hsa:79709; Q8NBJ5; Q8NC64"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"261.1"	"229.4"	"284.7"	"352.1"	"252.9"	"267.7"	"405.5"	"466.3"	"601.4"	"1617.7"	"1998.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NE71"	"ATP-binding cassette sub-family F member 1 OS=Homo sapiens OX=9606 GN=ABCF1 PE=1 SV=2"	"0.000"	""	"8"	"5"	"9"	"5"	"845"	"95.9"	"6.80"	"2270.72"	"14.92"	"5"	"4"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00005, Pf12848"	"23"	"ENSG00000204574; ENSG00000206490; ENSG00000225989; ENSG00000231129; ENSG00000232169; ENSG00000236149; ENSG00000236342"	"ABCF1"	"A2BF75; hsa:23; O14897; Q69YP6; Q8NE71"	"IL-18 signaling pathway"	"ABC-family proteins mediated transport"	"2"	"0"	"345.1"	"201.1"	"397.0"	"395.4"	"287.9"	"324.9"	"441.7"	"431.7"	"562.9"	"744.9"	"789.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05048"	"Cleavage stimulation factor subunit 1 OS=Homo sapiens OX=9606 GN=CSTF1 PE=1 SV=1"	"0.000"	""	"13"	"4"	"7"	"4"	"431"	"48.3"	"6.58"	"1001.34"	"14.88"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00400, Pf16699"	"1477"	"ENSG00000101138"	"CSTF1"	"hsa:1477; Q05048; Q5QPD8"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"118.4"	"108.5"	"141.7"	"173.3"	"104.6"	"113.8"	"197.7"	"201.4"	"267.0"	"861.0"	"1430.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQW7"	"Xaa-Pro aminopeptidase 1 OS=Homo sapiens OX=9606 GN=XPNPEP1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"8"	"3"	"623"	"69.9"	"5.67"	"1604.84"	"14.88"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00557, Pf01321, Pf16188, Pf16189"	"7511"	"ENSG00000108039"	"XPNPEP1"	"A8K071; G5E9Y2; G8JLB2; hsa:7511; O15250; Q53EX6; Q8N3Q0; Q96D23; Q9NQW7"	""	""	"0"	"0"	"55.9"	"43.4"	"69.6"	"86.9"	"55.5"	"69.8"	"135.3"	"154.2"	"232.3"	"778.6"	"1583.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17480"	"Nucleolar transcription factor 1 OS=Homo sapiens OX=9606 GN=UBTF PE=1 SV=1"	"0.000"	""	"7"	"4"	"8"	"4"	"764"	"89.4"	"5.81"	"1598.66"	"14.87"	"4"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09011, Pf14887"	"7343"	"ENSG00000108312"	"UBTF"	"A8K6R8; hsa:7343; P17480"	"Ectoderm differentiation"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; RNA Polymerase I Promoter Opening"	"6"	"0"	"241.2"	"243.2"	"261.1"	"303.4"	"261.2"	"248.0"	"397.7"	"432.3"	"607.2"	"999.0"	"988.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14974"	"Importin subunit beta-1 OS=Homo sapiens OX=9606 GN=KPNB1 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"876"	"97.1"	"4.78"	"1598.69"	"14.87"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf03810"	"3837"	"ENSG00000108424"	"KPNB1"	"B7ZAV6; D3DTT3; hsa:3837; Q14637; Q14974; Q53XN2; Q96J27"	"Sterol regulatory element-binding proteins (SREBP) signaling; 22q11.2 copy number variation syndrome"	"Assembly of the ORC complex at the origin of replication; Neutrophil degranulation; ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Nuclear import of Rev protein; Apoptosis induced DNA fragmentation; Interferon alpha/beta signaling; Regulation of cholesterol biosynthesis by SREBP (SREBF); SARS-CoV-1 activates/modulates innate immune responses; Initiation of Nuclear Envelope (NE) Reformation; Postmitotic nuclear pore complex (NPC) reformation; Inhibition of nitric oxide production"	"15"	"0"	"249.1"	"216.1"	"315.5"	"473.8"	"255.1"	"267.5"	"531.1"	"580.0"	"806.6"	"2424.9"	"3712.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4L7"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 OS=Homo sapiens OX=9606 GN=SMARCAD1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"1026"	"117.3"	"5.55"	"912.28"	"14.86"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"56916"	"ENSG00000163104"	"SMARCAD1"	"B7Z799; hsa:56916; Q05D56; Q96SX1; Q9H017; Q9H4L7; Q9H860; Q9NPU9; Q9ULU7"	""	""	"0"	"0"	"133.5"	"129.5"	"164.6"	"211.8"	"140.3"	"135.1"	"218.3"	"231.8"	"270.8"	"731.3"	"1183.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W42"	"THO complex subunit 6 homolog OS=Homo sapiens OX=9606 GN=THOC6 PE=1 SV=1"	"0.000"	""	"12"	"4"	"8"	"4"	"341"	"37.5"	"7.43"	"1990.12"	"14.85"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"79228"	"ENSG00000131652"	"THOC6"	"B2RA85; hsa:79228; Q86W42; Q8NBR1; Q9BTV9"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"170.9"	"194.1"	"180.6"	"204.3"	"177.4"	"177.0"	"277.8"	"309.7"	"365.1"	"702.6"	"1033.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96LB3"	"Intraflagellar transport protein 74 homolog OS=Homo sapiens OX=9606 GN=IFT74 PE=1 SV=1"	"0.000"	""	"11"	"4"	"7"	"4"	"600"	"69.2"	"6.00"	"1220.51"	"14.85"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"80173"	"ENSG00000096872"	"IFT74"	"hsa:80173; Q3B789; Q5VY34; Q6PGQ8; Q96LB3; Q9H643; Q9H8G7"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Alstrom syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport"	"5"	"0"	"286.9"	"82.5"	"408.2"	"373.2"	"257.3"	"286.1"	"316.6"	"278.0"	"327.8"	"552.0"	"1008.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26373"	"60S ribosomal protein L13 OS=Homo sapiens OX=9606 GN=RPL13 PE=1 SV=4"	"0.000"	""	"19"	"5"	"9"	"5"	"211"	"24.2"	"11.65"	"1301.99"	"14.84"	"4"	"5"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01294"	"6137"	"ENSG00000167526"	"RPL13"	"B4DLX3; F5H1S2; hsa:6137; P26373; Q3KQT8; Q567Q8; Q9BPX0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"531.4"	"491.9"	"686.4"	"784.3"	"545.7"	"615.0"	"852.3"	"844.7"	"957.7"	"2016.3"	"3141.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15555"	"Microtubule-associated protein RP/EB family member 2 OS=Homo sapiens OX=9606 GN=MAPRE2 PE=1 SV=1"	"0.000"	""	"10"	"3"	"8"	"3"	"327"	"37.0"	"5.57"	"1350.53"	"14.81"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"10982"	"ENSG00000166974"	"MAPRE2"	"B2RE21; B3KR39; B4DJV4; B7Z2L3; E9PHR3; F5H1V8; G5E9I6; hsa:10982; Q15555; Q9UQ33"	"Ciliary landscape"	""	"1"	"0"	"62.8"	"45.9"	"82.7"	"93.0"	"58.3"	"59.2"	"184.4"	"208.6"	"384.7"	"1011.9"	"1186.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVC0"	"RNA polymerase-associated protein LEO1 OS=Homo sapiens OX=9606 GN=LEO1 PE=1 SV=1"	"0.000"	""	"12"	"7"	"12"	"7"	"666"	"75.4"	"4.51"	"2519.43"	"14.81"	"7"	"5"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf04004"	"123169"	"ENSG00000166477"	"LEO1"	"hsa:123169; Q8WVC0; Q96N99"	"Endoderm differentiation"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; Formation of the beta-catenin:TCF transactivating complex"	"6"	"0"	"683.3"	"599.6"	"698.9"	"790.0"	"564.9"	"615.2"	"841.1"	"834.9"	"933.7"	"1499.7"	"1878.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60842"	"Eukaryotic initiation factor 4A-I OS=Homo sapiens OX=9606 GN=EIF4A1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"8"	"1"	"406"	"46.1"	"5.48"	"1822.07"	"14.81"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1973"	"ENSG00000161960"	"EIF4A1"	"B2R6L8; D3DTP9; hsa:1973; J3QLC4; P04765; P60842; Q5U018; Q61516"	"Translation factors; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Interferon type I signaling pathways"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Deadenylation of mRNA; ISG15 antiviral mechanism"	"11"	"0"	"33.6"	"60.0"	"34.9"	"53.9"	"35.7"	"36.9"	"60.7"	"77.1"	"85.0"	"165.2"	"237.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75179"	"Ankyrin repeat domain-containing protein 17 OS=Homo sapiens OX=9606 GN=ANKRD17 PE=1 SV=3"	"0.000"	""	"2"	"5"	"7"	"2"	"2603"	"274.1"	"6.52"	"1869.01"	"14.79"	"4"	"3"	"stress response;developmental processes;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf00013, Pf12796"	"26057"	"ENSG00000132466"	"ANKRD17"	"E7EUV3; G5E964; hsa:26057; O75179; Q6PJ85; Q6PK85; Q6PKA2; Q86XI3; Q8NDR5; Q96I86; Q9H288; Q9H6J9"	""	""	"0"	"3"	"145.1"	"124.1"	"180.8"	"217.0"	"161.1"	"132.1"	"239.2"	"233.0"	"297.1"	"529.9"	"643.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19022"	"Cadherin-2 OS=Homo sapiens OX=9606 GN=CDH2 PE=1 SV=4"	"0.000"	""	"4"	"4"	"6"	"4"	"906"	"99.7"	"4.81"	"723.60"	"14.78"	"2"	"3"	"cell adhesion;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00028, Pf01049, Pf08758"	"1000"	"ENSG00000170558"	"CDH2"	"A8MWK3; B0YIY6; hsa:1000; P19022; Q14923; Q8N173"	"Neural crest differentiation; Arrhythmogenic right ventricular cardiomyopathy; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Splicing factor NOVA regulated synaptic proteins; Epithelial to mesenchymal transition in colorectal cancer; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Myogenesis; Adherens junctions interactions"	"16"	"0"	"193.6"	"174.6"	"247.6"	"258.7"	"173.5"	"196.6"	"276.6"	"293.4"	"343.0"	"702.9"	"1033.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13310"	"Polyadenylate-binding protein 4 OS=Homo sapiens OX=9606 GN=PABPC4 PE=1 SV=1"	"0.000"	""	"8"	"4"	"8"	"1"	"644"	"70.7"	"9.26"	"1483.86"	"14.77"	"4"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00658"	"8761"	"ENSG00000090621"	"PABPC4"	"B1ANQ8; hsa:8761; Q13310; Q4VC03; Q6P0N3"	""	""	"0"	"0"	"50.9"	"46.8"	"67.7"	"87.7"	"64.2"	"59.0"	"82.6"	"90.2"	"100.7"	"179.5"	"269.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62424"	"60S ribosomal protein L7a OS=Homo sapiens OX=9606 GN=RPL7A PE=1 SV=2"	"0.000"	""	"18"	"6"	"11"	"6"	"266"	"30.0"	"10.61"	"2163.92"	"14.76"	"6"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01248"	"6130"	"ENSG00000148303; ENSG00000280858"	"RPL7A"	"hsa:6130; P11518; P62424; Q5T8U4"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"734.9"	"703.3"	"874.5"	"1041.6"	"702.9"	"707.2"	"1110.7"	"1150.2"	"1389.9"	"3071.4"	"4943.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ48"	"Leucine zipper transcription factor-like protein 1 OS=Homo sapiens OX=9606 GN=LZTFL1 PE=1 SV=1"	"0.000"	""	"15"	"3"	"4"	"3"	"299"	"34.6"	"5.36"	"373.57"	"14.73"	"1"	"3"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf15294"	"54585"	"ENSG00000163818"	"LZTFL1"	"B3KSI9; B4E0K7; hsa:54585; Q8TC61; Q9NQ48; Q9NQ56"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"5"	"0"	"43.7"	"38.9"	"42.4"	"60.6"	"35.2"	"38.8"	"83.8"	"100.9"	"136.5"	"849.7"	"1392.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01484"	"Ankyrin-2 OS=Homo sapiens OX=9606 GN=ANK2 PE=1 SV=4"	"0.000"	""	"1"	"5"	"10"	"1"	"3957"	"433.4"	"5.14"	"1645.12"	"14.72"	"5"	"5"	"cell-cell signaling;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00023, Pf00531, Pf00791, Pf12796, Pf17809"	"287"	"ENSG00000145362"	"ANK2"	"hsa:287; Q01484; Q01485; Q08AC7; Q08AC8; Q7Z3L5"	""	"Interaction between L1 and Ankyrins; COPI-mediated anterograde transport"	"2"	"1"	"138.9"	"125.9"	"157.6"	"181.1"	"131.7"	"139.1"	"222.9"	"235.7"	"361.9"	"897.4"	"1216.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75822"	"Eukaryotic translation initiation factor 3 subunit J OS=Homo sapiens OX=9606 GN=EIF3J PE=1 SV=2"	"0.000"	""	"24"	"4"	"5"	"4"	"258"	"29.0"	"4.83"	"979.96"	"14.71"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08597"	"8669"	"ENSG00000104131"	"EIF3J"	"B4DUI3; F5H425; hsa:8669; O75822; Q9BUD2; Q9H8Q2; Q9UI65"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"70.9"	"51.9"	"84.3"	"109.2"	"73.3"	"104.9"	"211.1"	"222.8"	"308.8"	"2137.7"	"2820.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00232"	"26S proteasome non-ATPase regulatory subunit 12 OS=Homo sapiens OX=9606 GN=PSMD12 PE=1 SV=3"	"0.000"	""	"12"	"4"	"6"	"4"	"456"	"52.9"	"7.65"	"898.97"	"14.70"	"2"	"4"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf18098"	"5718"	"ENSG00000197170"	"PSMD12"	"A6NP15; hsa:5718; O00232; Q53HA2; Q6P053"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"86.9"	"72.5"	"102.6"	"151.2"	"89.5"	"97.8"	"132.9"	"170.8"	"238.4"	"769.7"	"1612.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNX3"	"60S ribosomal protein L26-like 1 OS=Homo sapiens OX=9606 GN=RPL26L1 PE=1 SV=1"	"0.000"	""	"32"	"5"	"11"	"5"	"145"	"17.2"	"10.55"	"1868.00"	"14.69"	"5"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00467, Pf16906"	"51121"	"ENSG00000037241"	"RPL26L1"	"B3KY82; D3DQM0; hsa:51121; Q9UNX3"	""	"Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"13"	"0"	"630.8"	"677.2"	"665.9"	"834.1"	"611.7"	"660.3"	"953.8"	"1034.1"	"1171.4"	"2162.9"	"2968.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41227"	"N-alpha-acetyltransferase 10 OS=Homo sapiens OX=9606 GN=NAA10 PE=1 SV=1"	"0.000"	""	"19"	"3"	"5"	"3"	"235"	"26.4"	"5.64"	"790.47"	"14.60"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"8260"	"ENSG00000102030"	"NAA10"	"A6NM98; hsa:8260; P41227"	""	""	"0"	"0"	"74.2"	"82.3"	"97.6"	"136.7"	"81.5"	"57.5"	"384.6"	"611.3"	"1216.5"	"374.2"	"543.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00471"	"Exocyst complex component 5 OS=Homo sapiens OX=9606 GN=EXOC5 PE=1 SV=1"	"0.000"	""	"8"	"4"	"8"	"4"	"708"	"81.8"	"6.71"	"1443.45"	"14.60"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf07393"	"10640"	"ENSG00000070367"	"EXOC5"	"B2R6C5; hsa:10640; O00471; Q8IW24"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"31.9"	"25.6"	"33.1"	"45.4"	"36.0"	"45.8"	"141.0"	"167.2"	"282.7"	"576.8"	"704.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32969"	"60S ribosomal protein L9 OS=Homo sapiens OX=9606 GN=RPL9 PE=1 SV=1"	"0.000"	""	"22"	"3"	"6"	"3"	"192"	"21.9"	"9.95"	"1166.06"	"14.58"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00347"	"6133"	"ENSG00000163682"	"RPL9; RPL9P7; RPL9P8; RPL9P9"	"hsa:6133; P32969"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"161.3"	"158.4"	"172.7"	"226.6"	"151.5"	"168.0"	"270.8"	"281.8"	"331.5"	"834.4"	"1273.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12789"	"General transcription factor 3C polypeptide 1 OS=Homo sapiens OX=9606 GN=GTF3C1 PE=1 SV=4"	"0.000"	""	"5"	"8"	"11"	"8"	"2109"	"238.7"	"7.30"	"2523.93"	"14.57"	"7"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04182"	"2975"	"ENSG00000077235"	"GTF3C1"	"B2RP21; hsa:2975; Q12789; Q12838; Q6DKN9; Q9Y4W9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"198.5"	"179.6"	"243.0"	"304.0"	"198.0"	"173.1"	"359.8"	"370.8"	"480.2"	"1287.2"	"2033.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YQ8"	"Copine-8 OS=Homo sapiens OX=9606 GN=CPNE8 PE=1 SV=2"	"0.000"	""	"10"	"5"	"6"	"5"	"564"	"63.1"	"5.96"	"969.86"	"14.55"	"2"	"4"	"other biological processes"	"plasma membrane;other membranes"	"other molecular function"	"Pf00168, Pf07002"	"144402"	"ENSG00000139117"	"CPNE8"	"hsa:144402; Q2TB41; Q86VY2; Q86YQ8"	""	"RHOD GTPase cycle; CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"4"	"0"	"101.1"	"84.2"	"129.2"	"156.3"	"85.5"	"105.6"	"269.3"	"261.5"	"510.5"	"2510.9"	"4133.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T8P6"	"RNA-binding protein 26 OS=Homo sapiens OX=9606 GN=RBM26 PE=1 SV=3"	"0.000"	""	"6"	"5"	"9"	"4"	"1007"	"113.5"	"9.16"	"2052.77"	"14.54"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01480"	"64062"	"ENSG00000139746"	"RBM26"	"B4DZE0; hsa:64062; Q2NKM2; Q2NKQ2; Q5CZH8; Q5T8P5; Q5T8P6; Q5T8P8; Q5U5P5; Q5W0G7; Q8N3H5; Q96K92; Q96SZ3; Q9H2F8; Q9H7F9; Q9P1G7"	""	""	"0"	"1"	"141.5"	"144.7"	"166.8"	"221.9"	"148.4"	"135.1"	"250.0"	"249.6"	"306.6"	"726.3"	"957.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT25"	"Serine/threonine-protein kinase MRCK alpha OS=Homo sapiens OX=9606 GN=CDC42BPA PE=1 SV=1"	"0.000"	""	"4"	"5"	"8"	"4"	"1732"	"197.2"	"6.58"	"1514.70"	"14.53"	"4"	"4"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433, Pf00780, Pf08826, Pf15796"	"8476"	"ENSG00000143776"	"CDC42BPA"	"hsa:8476; O75039; Q59GZ1; Q5H9N9; Q5T797; Q5VT25; Q5VT26; Q5VT27; Q86XX2; Q86XX3; Q99646"	"Male infertility"	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"5"	"1"	"132.2"	"109.7"	"177.3"	"207.3"	"179.7"	"371.0"	"1067.2"	"1137.6"	"1236.7"	"1112.0"	"1240.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94901"	"SUN domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUN1 PE=1 SV=3"	"0.000"	""	"5"	"3"	"6"	"3"	"812"	"90.0"	"7.08"	"1425.26"	"14.53"	"3"	"3"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"141.4"	"87.7"	"151.4"	"164.6"	"140.7"	"150.0"	"193.0"	"197.1"	"239.1"	"522.6"	"695.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCG8"	"Pre-mRNA-splicing factor CWC22 homolog OS=Homo sapiens OX=9606 GN=CWC22 PE=1 SV=3"	"0.000"	""	"5"	"3"	"6"	"3"	"908"	"105.4"	"7.03"	"1696.92"	"14.45"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf02847"	"57703"	"ENSG00000163510"	"CWC22"	"hsa:57703; Q05DC2; Q4G135; Q52LF0; Q6PEX2; Q7Z6I0; Q9H5L3; Q9H6Q6; Q9HCG8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"70.9"	"66.8"	"85.5"	"100.5"	"75.8"	"83.7"	"132.0"	"143.8"	"175.9"	"619.9"	"1259.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQR0"	"Sex comb on midleg-like protein 2 OS=Homo sapiens OX=9606 GN=SCML2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"3"	"700"	"77.2"	"8.54"	"1385.47"	"14.43"	"3"	"3"	"other biological processes"	"nucleus"	""	"Pf00536, Pf02820, Pf12140, Pf17208"	"10389"	"ENSG00000102098"	"SCML2"	"hsa:10389; Q5JXE6; Q86U98; Q8IWD0; Q8NDP2; Q9UGC5; Q9UQR0"	""	""	"0"	"0"	"158.0"	"143.3"	"167.4"	"204.4"	"137.7"	"135.8"	"239.2"	"261.5"	"346.3"	"722.9"	"917.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z794"	"Keratin, type II cytoskeletal 1b OS=Homo sapiens OX=9606 GN=KRT77 PE=1 SV=3"	"0.000"	""	"5"	"3"	"8"	"1"	"578"	"61.9"	"5.99"	"1424.21"	"14.41"	"3"	"3"	"other biological processes"	"plasma membrane;cytosol;cytoskeleton"	"bone, tooth or skin structural activity"	"Pf00038, Pf16208"	"374454"	"ENSG00000189182"	"KRT77"	"hsa:374454; Q7RTS8; Q7Z794"	""	"Formation of the cornified envelope"	"2"	"0"	"8.1"	"9.4"	"141.5"	"0.0"	"1.2"	"0.0"	"8.3"	"8.5"	"10.4"	"9.0"	"6.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12872"	"Splicing factor, suppressor of white-apricot homolog OS=Homo sapiens OX=9606 GN=SFSWAP PE=1 SV=3"	"0.000"	""	"5"	"5"	"10"	"5"	"951"	"104.8"	"8.05"	"1532.75"	"14.37"	"5"	"5"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01805, Pf09750"	"6433"	"ENSG00000061936"	"SFSWAP"	"B2RN45; B7ZM97; F5H6B8; hsa:6433; Q12872; Q6PJF7"	"mRNA processing"	""	"1"	"0"	"252.7"	"265.4"	"247.0"	"297.8"	"256.8"	"235.4"	"347.8"	"373.0"	"447.0"	"848.6"	"1022.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99584"	"Protein S100-A13 OS=Homo sapiens OX=9606 GN=S100A13 PE=1 SV=1"	"0.000"	""	"21"	"2"	"4"	"2"	"98"	"11.5"	"6.16"	"514.39"	"14.37"	"1"	"2"	"transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01023"	"6284"	"ENSG00000189171"	"S100A13"	"hsa:6284; Q52PI9; Q6FGF8; Q99584"	""	""	"0"	"0"	"29.0"	"28.2"	"41.5"	"63.8"	"31.9"	"36.7"	"102.0"	"108.2"	"173.3"	"2165.2"	"4423.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01844"	"RNA-binding protein EWS OS=Homo sapiens OX=9606 GN=EWSR1 PE=1 SV=1"	"0.000"	""	"8"	"4"	"7"	"4"	"656"	"68.4"	"9.33"	"1193.58"	"14.35"	"3"	"4"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00641"	"2130"	"ENSG00000182944"	"EWSR1"	"B0QYK1; hsa:2130; Q01844; Q5THL0; Q92635; Q96FE8; Q96MN4; Q96MX4; Q9BWA2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"331.3"	"333.6"	"355.2"	"414.0"	"304.6"	"307.4"	"460.1"	"469.0"	"557.9"	"897.8"	"1143.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95639"	"Cleavage and polyadenylation specificity factor subunit 4 OS=Homo sapiens OX=9606 GN=CPSF4 PE=1 SV=1"	"0.000"	""	"17"	"3"	"5"	"3"	"269"	"30.2"	"8.31"	"884.32"	"14.31"	"2"	"3"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf00642, Pf15663"	"10898"	"ENSG00000160917"	"CPSF4"	"D6W5S8; hsa:10898; O95639; Q6FGE6; Q86TF8; Q9BTW6"	"mRNA processing"	"Transport of Mature mRNA Derived from an Intronless Transcript; tRNA processing in the nucleus; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs; Inhibition of Host mRNA Processing and RNA Silencing"	"8"	"0"	"348.6"	"365.5"	"359.6"	"402.9"	"316.5"	"201.9"	"452.9"	"490.9"	"550.0"	"1259.4"	"2097.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TAP6"	"U3 small nucleolar RNA-associated protein 14 homolog C OS=Homo sapiens OX=9606 GN=UTP14C PE=1 SV=1"	"0.000"	""	"6"	"3"	"8"	"1"	"766"	"87.1"	"7.15"	"1727.63"	"14.21"	"3"	"3"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04615"	"9724"	"ENSG00000253797"	"UTP14C"	"hsa:9724; Q5FWG3; Q5TAP6; Q92555"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"9.2"	"6.4"	"19.1"	"18.6"	"15.1"	"24.6"	"32.9"	"31.0"	"27.2"	"20.3"	"23.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2Y7"	"Zinc finger protein 106 OS=Homo sapiens OX=9606 GN=ZNF106 PE=1 SV=1"	"0.000"	""	"3"	"3"	"5"	"3"	"1883"	"208.8"	"7.15"	"863.58"	"14.21"	"2"	"3"	"signal transduction"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf00400"	"64397"	"ENSG00000103994"	"ZNF106"	"B4DZ40; E9PE29; hsa:64397; Q6NSD9; Q6PEK1; Q86T43; Q86T45; Q86T50; Q86T58; Q86TA9; Q96M37; Q9H2Y7; Q9H7B8"	""	""	"0"	"0"	"75.8"	"61.3"	"95.5"	"105.2"	"68.1"	"58.3"	"118.9"	"124.3"	"139.5"	"242.5"	"279.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13557"	"Calcium/calmodulin-dependent protein kinase type II subunit delta OS=Homo sapiens OX=9606 GN=CAMK2D PE=1 SV=3"	"0.000"	""	"9"	"4"	"9"	"2"	"499"	"56.3"	"7.25"	"1741.39"	"14.20"	"4"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08332"	"817"	"ENSG00000145349"	"CAMK2D"	"A8MVS8; hsa:817; Q13557; Q52PK4; Q59G21; Q8N553; Q9UGH6; Q9UQE9"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; SRF and miRs in smooth muscle differentiation and proliferation; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Disturbed pathways in Duchenne Muscular Dystrophy; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Ion homeostasis; Ion transport by P-type ATPases; Assembly and cell surface presentation of NMDA receptors; Signaling by BRAF and RAF1 fusions; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB"	"33"	"2"	"475.9"	"507.6"	"574.8"	"754.9"	"465.6"	"454.5"	"857.3"	"932.3"	"1290.3"	"3485.0"	"4486.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y520"	"Protein PRRC2C OS=Homo sapiens OX=9606 GN=PRRC2C PE=1 SV=4"	"0.000"	""	"2"	"4"	"8"	"4"	"2896"	"316.7"	"9.13"	"1507.14"	"14.20"	"4"	"4"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	""	"Pf07001"	"23215"	"ENSG00000117523"	"PRRC2C"	"hsa:23215; Q05DM8; Q49A39; Q6PD54; Q9H2N2; Q9HA05; Q9NSM8; Q9NXL3; Q9UF29; Q9UPQ6; Q9Y520"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"171.2"	"151.5"	"174.4"	"217.2"	"147.9"	"155.3"	"210.2"	"225.9"	"264.8"	"415.2"	"568.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37108"	"Signal recognition particle 14 kDa protein OS=Homo sapiens OX=9606 GN=SRP14 PE=1 SV=2"	"0.000"	""	"37"	"7"	"15"	"7"	"136"	"14.6"	"10.04"	"3841.71"	"14.19"	"7"	"4"	"transport"	"non-structural extracellular;cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02290"	"6727"	"ENSG00000140319"	"SRP14"	"B5BUF5; hsa:6727; P37108; Q6B0K5; Q96Q14"	""	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane"	"2"	"0"	"2235.6"	"2275.3"	"2200.9"	"2313.3"	"1929.7"	"1994.0"	"2689.4"	"2729.1"	"2758.6"	"2381.8"	"3243.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NNW5"	"WD repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=WDR6 PE=1 SV=1"	"0.000"	""	"4"	"4"	"8"	"4"	"1121"	"121.6"	"6.87"	"1528.39"	"14.18"	"4"	"4"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00400"	"11180"	"ENSG00000178252"	"WDR6"	"B4DHK2; hsa:11180; Q3MIT1; Q9NNW5; Q9UF63"	""	"RHOV GTPase cycle; RHOU GTPase cycle; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"5"	"0"	"215.5"	"208.5"	"260.1"	"319.4"	"217.2"	"199.2"	"389.0"	"395.7"	"559.6"	"1823.2"	"2907.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYD1"	"Eukaryotic peptide chain release factor GTP-binding subunit ERF3B OS=Homo sapiens OX=9606 GN=GSPT2 PE=1 SV=2"	"0.000"	""	"8"	"4"	"7"	"1"	"628"	"68.8"	"5.43"	"1028.37"	"14.16"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009, Pf03143, Pf07145"	"23708"	"ENSG00000189369"	"GSPT2"	"hsa:23708; Q8IYD1; Q9H909; Q9NVY0; Q9NY44"	"Translation factors"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"5"	"0"	"25.6"	"14.9"	"38.6"	"41.2"	"21.7"	"28.5"	"60.4"	"66.3"	"104.4"	"343.1"	"472.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99575"	"Ribonucleases P/MRP protein subunit POP1 OS=Homo sapiens OX=9606 GN=POP1 PE=1 SV=2"	"0.001"	""	"4"	"3"	"5"	"3"	"1024"	"114.6"	"9.22"	"242.59"	"14.15"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06978, Pf08170"	"10940"	"ENSG00000104356"	"POP1"	"A8K5W9; hsa:10940; Q15037; Q99575"	""	"tRNA processing in the nucleus"	"1"	"0"	"695.2"	"131.4"	"1009.6"	"746.8"	"579.7"	"567.7"	"655.4"	"464.4"	"518.1"	"691.9"	"1411.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15427"	"Splicing factor 3B subunit 4 OS=Homo sapiens OX=9606 GN=SF3B4 PE=1 SV=1"	"0.000"	""	"15"	"4"	"7"	"4"	"424"	"44.4"	"8.56"	"797.61"	"14.15"	"3"	"4"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"10262"	"ENSG00000143368"	"SF3B4"	"hsa:10262; Q15427; Q5SZ63"	"mRNA processing; 10q22q23 copy number variation"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"4"	"0"	"306.4"	"421.0"	"350.3"	"420.5"	"299.0"	"323.4"	"468.9"	"516.2"	"514.7"	"1184.5"	"1726.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61218"	"DNA-directed RNA polymerases I, II, and III subunit RPABC2 OS=Homo sapiens OX=9606 GN=POLR2F PE=1 SV=1"	"0.000"	""	"32"	"3"	"5"	"3"	"127"	"14.5"	"4.22"	"540.50"	"14.14"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01192"	"5435"	"ENSG00000100142"	"POLR2F"	"hsa:5435; P41584; P61218; Q6IAY3"	"Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"56"	"0"	"296.8"	"300.8"	"292.7"	"402.9"	"283.2"	"270.6"	"462.1"	"504.2"	"641.8"	"1261.1"	"1364.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NS86"	"LanC-like protein 2 OS=Homo sapiens OX=9606 GN=LANCL2 PE=1 SV=1"	"0.000"	""	"9"	"3"	"5"	"3"	"450"	"50.8"	"7.43"	"790.60"	"14.13"	"2"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf05147"	"55915"	"ENSG00000132434"	"LANCL2"	"B2R8D4; hsa:55915; Q6NSL4; Q8TCQ3; Q9BSR1; Q9NS86"	""	""	"0"	"0"	"67.7"	"61.0"	"135.8"	"113.2"	"71.3"	"81.1"	"152.5"	"162.7"	"284.1"	"729.8"	"1094.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15020"	"Squamous cell carcinoma antigen recognized by T-cells 3 OS=Homo sapiens OX=9606 GN=SART3 PE=1 SV=1"	"0.000"	""	"5"	"3"	"5"	"3"	"963"	"109.9"	"5.57"	"1111.67"	"14.09"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00076, Pf05391, Pf16605"	"9733"	"ENSG00000075856"	"SART3"	"A8K2E4; B7ZKM0; hsa:9733; Q15020; Q2M2H0; Q58F06; Q8IUS1; Q96J95"	""	""	"0"	"0"	"489.6"	"421.2"	"561.2"	"621.0"	"468.3"	"388.2"	"627.0"	"620.4"	"640.2"	"878.8"	"1228.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9A6"	"Leucine-rich repeat-containing protein 40 OS=Homo sapiens OX=9606 GN=LRRC40 PE=1 SV=1"	"0.000"	""	"8"	"5"	"10"	"5"	"602"	"68.2"	"6.43"	"1620.02"	"14.06"	"5"	"5"	""	""	""	"Pf00560, Pf13855"	"55631"	"ENSG00000066557"	"LRRC40"	"hsa:55631; Q9BTR7; Q9H9A6; Q9NSK1; Q9NXC1"	""	""	"0"	"0"	"103.4"	"104.7"	"105.8"	"156.2"	"98.9"	"109.8"	"216.1"	"220.2"	"322.5"	"1979.7"	"2911.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L2E3"	"ATP-dependent RNA helicase DHX30 OS=Homo sapiens OX=9606 GN=DHX30 PE=1 SV=1"	"0.000"	""	"3"	"3"	"8"	"3"	"1194"	"133.9"	"8.78"	"1484.99"	"14.05"	"3"	"3"	"cell organization and biogenesis;developmental processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"22907"	"ENSG00000132153"	"DHX30"	"A8K5F1; hsa:22907; O94965; Q7L2E3; Q7Z753; Q96CH4; Q9NUQ0"	""	""	"0"	"0"	"91.4"	"61.4"	"95.4"	"132.3"	"78.1"	"73.6"	"145.3"	"135.8"	"192.6"	"322.3"	"473.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14203"	"Dynactin subunit 1 OS=Homo sapiens OX=9606 GN=DCTN1 PE=1 SV=3"	"0.000"	""	"5"	"4"	"6"	"3"	"1278"	"141.6"	"5.81"	"1415.47"	"14.02"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf12455"	"1639"	"ENSG00000204843"	"DCTN1"	"A8MY36; B4DM45; E9PFS5; E9PGE1; G5E9H4; hsa:1639; O95296; Q14203; Q6IQ37; Q9BRM9; Q9UIU1; Q9UIU2"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Signaling by ALK fusions and activated point mutants; XBP1(S) activates chaperone genes"	"6"	"0"	"43.5"	"34.3"	"47.7"	"59.9"	"33.1"	"46.9"	"59.5"	"62.2"	"84.2"	"205.1"	"377.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVG4"	"Protein PBDC1 OS=Homo sapiens OX=9606 GN=PBDC1 PE=1 SV=1"	"0.000"	""	"18"	"4"	"7"	"4"	"233"	"26.0"	"4.79"	"1181.51"	"14.01"	"3"	"4"	""	""	""	"Pf04669"	"51260"	"ENSG00000102390"	"PBDC1"	"hsa:51260; Q9BVG4"	""	""	"0"	"0"	"181.4"	"148.1"	"217.2"	"277.7"	"165.3"	"178.8"	"327.3"	"331.7"	"510.1"	"1197.4"	"1623.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0ZGT2"	"Nexilin OS=Homo sapiens OX=9606 GN=NEXN PE=1 SV=1"	"0.000"	""	"4"	"3"	"7"	"3"	"675"	"80.6"	"5.33"	"1479.04"	"14.01"	"3"	"3"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"91624"	"ENSG00000162614"	"NEXN"	"A0PJ84; B4DPZ7; hsa:91624; Q0D2H2; Q0ZGT2; Q14CC2; Q14CC3; Q16081; Q7Z2X0; Q96DL0; Q9Y2V1"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"160.8"	"163.1"	"201.6"	"226.6"	"159.8"	"165.2"	"240.5"	"255.0"	"315.8"	"711.6"	"1568.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15003"	"Condensin complex subunit 2 OS=Homo sapiens OX=9606 GN=NCAPH PE=1 SV=3"	"0.000"	""	"6"	"3"	"6"	"3"	"741"	"82.5"	"5.06"	"1527.47"	"14.00"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05786"	"23397"	"ENSG00000121152"	"NCAPH"	"B4E189; hsa:23397; Q15003; Q8TB87"	"2q11.2 copy number variation syndrome"	"Condensation of Prometaphase Chromosomes"	"2"	"0"	"135.9"	"118.3"	"238.7"	"184.3"	"148.3"	"181.4"	"400.6"	"327.9"	"374.3"	"741.5"	"956.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14315"	"Filamin-C OS=Homo sapiens OX=9606 GN=FLNC PE=1 SV=3"	"0.000"	""	"2"	"4"	"6"	"1"	"2725"	"290.8"	"5.97"	"874.24"	"13.95"	"2"	"4"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00630"	"2318"	"ENSG00000128591"	"FLNC"	"B2ZZ88; hsa:2318; O95303; Q07985; Q14315; Q9NS12; Q9NYE5; Q9UMR8; Q9Y503"	"Focal adhesion; MAPK signaling pathway; Ebola virus infection in host; NPHP1 deletion syndrome; 13q12.12 copy number variation"	"Cell-extracellular matrix interactions"	"6"	"0"	"79.3"	"124.4"	"60.2"	"81.5"	"63.1"	"66.3"	"102.1"	"113.3"	"115.1"	"172.9"	"192.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H501"	"ESF1 homolog OS=Homo sapiens OX=9606 GN=ESF1 PE=1 SV=1"	"0.000"	""	"5"	"4"	"8"	"4"	"851"	"98.7"	"5.11"	"1542.46"	"13.94"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08159"	"51575"	"ENSG00000089048"	"ESF1"	"hsa:51575; Q86X92; Q9H501; Q9H9Q5; Q9HA35; Q9NX93; Q9P1S6"	""	""	"0"	"0"	"167.8"	"145.2"	"208.7"	"284.2"	"170.9"	"183.6"	"286.9"	"269.3"	"364.9"	"770.8"	"1069.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16513"	"Serine/threonine-protein kinase N2 OS=Homo sapiens OX=9606 GN=PKN2 PE=1 SV=1"	"0.000"	""	"4"	"4"	"8"	"4"	"984"	"112.0"	"6.30"	"1449.94"	"13.92"	"4"	"4"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433, Pf02185"	"5586"	"ENSG00000065243"	"PKN2"	"B4DQ21; B4DTP5; B4DVG1; D3DT24; hsa:5586; Q08AF4; Q16513; Q9H1W4"	"PI3K-Akt signaling pathway"	"RAC1 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; RHO GTPases activate PKNs"	"6"	"0"	"161.8"	"158.8"	"186.5"	"194.2"	"158.8"	"166.7"	"370.0"	"371.6"	"586.7"	"1352.3"	"1467.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UDY2"	"Tight junction protein ZO-2 OS=Homo sapiens OX=9606 GN=TJP2 PE=1 SV=2"	"0.000"	""	"4"	"5"	"10"	"5"	"1190"	"133.9"	"7.40"	"1587.21"	"13.91"	"5"	"5"	"cell adhesion;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00595, Pf00625, Pf07653"	"9414"	"ENSG00000119139"	"TJP2"	"A2A3H9; B7Z2R8; B7Z7T6; F5H301; F5H886; hsa:9414; Q15883; Q5VXL0; Q5VXL1; Q8N756; Q8NI14; Q99839; Q9UDY0; Q9UDY1; Q9UDY2"	"1q21.1 copy number variation syndrome; 15q11q13 copy number variation"	"Signaling by Hippo; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"7"	"0"	"189.1"	"168.3"	"247.9"	"304.8"	"186.9"	"190.0"	"380.1"	"401.9"	"616.0"	"1863.0"	"2169.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4G0J3"	"La-related protein 7 OS=Homo sapiens OX=9606 GN=LARP7 PE=1 SV=1"	"0.000"	""	"6"	"4"	"8"	"4"	"582"	"66.9"	"9.55"	"1570.05"	"13.90"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf05383, Pf08777"	"51574"	"ENSG00000174720"	"LARP7"	"B2ZHN6; hsa:51574; Q3B7A9; Q4G0J3; Q9P1S7; Q9Y3Z8"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"241.9"	"133.9"	"270.7"	"297.6"	"209.9"	"206.0"	"303.8"	"291.4"	"301.0"	"476.2"	"752.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13177"	"Serine/threonine-protein kinase PAK 2 OS=Homo sapiens OX=9606 GN=PAK2 PE=1 SV=3"	"0.000"	""	"9"	"4"	"5"	"4"	"524"	"58.0"	"5.96"	"370.42"	"13.89"	"1"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00786"	"5062"	"ENSG00000180370"	"PAK2"	"hsa:5062; Q13154; Q13177; Q6ISC3"	"Integrin-mediated cell adhesion; Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Ras signaling; Pancreatic adenocarcinoma pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-Merlin signaling dysregulation; Neural crest cell migration during development; Neural crest cell migration in cancer; 3q29 copy number variation syndrome; Pleural mesothelioma; Regulation of actin cytoskeleton; ErbB signaling pathway"	"RHOV GTPase cycle; Regulation of activated PAK-2p34 by proteasome mediated degradation; MAPK6/MAPK4 signaling; Smooth Muscle Contraction; FCERI mediated MAPK activation; Generation of second messenger molecules; Regulation of PAK-2p34 activity by PS-GAP/RHG10; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; RHOU GTPase cycle; Ephrin signaling; Sema3A PAK dependent Axon repulsion; RHO GTPases activate PAKs; VEGFR2 mediated vascular permeability; Activation of RAC1; RHOH GTPase cycle; CD209 (DC-SIGN) signaling; CD28 dependent Vav1 pathway; Nef and signal transduction; Stimulation of the cell death response by PAK-2p34"	"43"	"0"	"63.4"	"60.2"	"79.3"	"95.1"	"61.6"	"64.4"	"120.8"	"114.8"	"136.8"	"1205.9"	"2562.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12277"	"Creatine kinase B-type OS=Homo sapiens OX=9606 GN=CKB PE=1 SV=1"	"0.000"	""	"15"	"4"	"7"	"4"	"381"	"42.6"	"5.59"	"1093.24"	"13.89"	"3"	"4"	"other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1152"	"ENSG00000166165"	"CKB"	"A8K236; B2R5R4; hsa:1152; P12277; Q2LE07; Q6FG40; Q9UC66"	""	"RND3 GTPase cycle; Creatine metabolism"	"2"	"0"	"136.4"	"141.2"	"200.8"	"395.5"	"116.0"	"114.2"	"262.9"	"292.8"	"397.2"	"902.9"	"1250.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99496"	"E3 ubiquitin-protein ligase RING2 OS=Homo sapiens OX=9606 GN=RNF2 PE=1 SV=1"	"0.000"	""	"13"	"4"	"7"	"3"	"336"	"37.6"	"6.84"	"1087.51"	"13.88"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf13923, Pf16207"	"6045"	"ENSG00000121481"	"RNF2"	"B2RBS7; B3KRH1; hsa:6045; Q5TEN1; Q5TEN2; Q99496"	"FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"Transcriptional Regulation by E2F6; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"11"	"1"	"279.6"	"216.9"	"302.5"	"338.4"	"267.0"	"283.4"	"408.3"	"414.4"	"553.7"	"1363.2"	"1909.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92905"	"COP9 signalosome complex subunit 5 OS=Homo sapiens OX=9606 GN=COPS5 PE=1 SV=4"	"0.000"	""	"16"	"5"	"7"	"5"	"334"	"37.6"	"6.54"	"645.64"	"13.88"	"2"	"5"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf18323"	"10987"	"ENSG00000121022"	"COPS5"	"hsa:10987; O15386; Q6AW95; Q86WQ4; Q92905; Q9BQ17"	""	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER"	"4"	"0"	"85.8"	"80.6"	"123.6"	"124.1"	"80.2"	"88.3"	"253.8"	"279.0"	"421.6"	"1760.1"	"3222.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95071"	"E3 ubiquitin-protein ligase UBR5 OS=Homo sapiens OX=9606 GN=UBR5 PE=1 SV=2"	"0.000"	""	"2"	"6"	"9"	"6"	"2799"	"309.2"	"5.85"	"1460.32"	"13.86"	"5"	"4"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00632, Pf00658, Pf11547"	"51366"	"ENSG00000104517"	"UBR5"	"B2RP24; hsa:51366; J3KMW7; O94970; O95071; Q9NPL3"	"Mesodermal commitment pathway"	""	"1"	"0"	"392.3"	"364.8"	"453.0"	"641.2"	"388.7"	"363.0"	"627.9"	"619.8"	"717.4"	"1212.6"	"1501.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10599"	"Thioredoxin OS=Homo sapiens OX=9606 GN=TXN PE=1 SV=3"	"0.000"	""	"40"	"4"	"7"	"4"	"105"	"11.7"	"4.92"	"1159.23"	"13.86"	"3"	"4"	"other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00085"	"7295"	"ENSG00000136810"	"TXN"	"B1ALW1; hsa:7295; O60744; P10599; Q53X69; Q96KI3; Q9UDG5"	"Selenium micronutrient network; Folic acid network; Selenium micronutrient network ; Folic acid network; Selenium micronutrient network; TNF-alpha signaling pathway; Complement system; Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling; TAR syndrome"	"Detoxification of Reactive Oxygen Species; Oxidative Stress Induced Senescence; TP53 Regulates Metabolic Genes; Interconversion of nucleotide di- and triphosphates; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; Regulation of FOXO transcriptional activity by acetylation; Protein repair"	"19"	"0"	"291.6"	"224.7"	"448.4"	"535.0"	"239.0"	"194.2"	"358.3"	"396.1"	"434.5"	"785.4"	"1154.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14684"	"Ribosomal RNA processing protein 1 homolog B OS=Homo sapiens OX=9606 GN=RRP1B PE=1 SV=3"	"0.000"	""	"8"	"4"	"6"	"4"	"758"	"84.4"	"9.76"	"1358.38"	"13.84"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05997"	"23076"	"ENSG00000160208"	"RRP1B"	"hsa:23076; Q14684; Q8TBZ4"	""	""	"0"	"0"	"160.8"	"153.9"	"176.8"	"201.5"	"178.9"	"146.1"	"235.4"	"248.9"	"337.4"	"598.1"	"744.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14745"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF1 OS=Homo sapiens OX=9606 GN=SLC9A3R1 PE=1 SV=4"	"0.000"	""	"14"	"4"	"7"	"4"	"358"	"38.8"	"5.77"	"1127.27"	"13.83"	"3"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;transporter activity;cytoskeletal activity;other molecular function"	"Pf00595, Pf09007"	"9368"	"ENSG00000109062"	"NHERF1"	"B3KY21; hsa:9368; O14745; O43552; Q86WQ5"	"TAR syndrome"	""	"1"	"0"	"74.9"	"55.6"	"89.5"	"126.3"	"73.6"	"58.4"	"195.2"	"224.1"	"385.5"	"1732.1"	"2601.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99549"	"M-phase phosphoprotein 8 OS=Homo sapiens OX=9606 GN=MPHOSPH8 PE=1 SV=2"	"0.000"	""	"3"	"2"	"6"	"2"	"860"	"97.1"	"6.06"	"1790.13"	"13.83"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00385, Pf12796"	"54737"	"ENSG00000196199"	"MPHOSPH8"	"B7Z6F9; hsa:54737; Q5JPE5; Q5JTQ0; Q86TK3; Q96MK4; Q99549; Q9BTP1"	""	""	"0"	"0"	"241.8"	"158.7"	"223.5"	"287.3"	"214.5"	"227.6"	"338.5"	"345.8"	"500.9"	"935.4"	"1223.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WJ1"	"Chromodomain-helicase-DNA-binding protein 1-like OS=Homo sapiens OX=9606 GN=CHD1L PE=1 SV=3"	"0.000"	""	"6"	"4"	"6"	"4"	"897"	"100.9"	"6.90"	"742.06"	"13.77"	"2"	"4"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00176, Pf00271"	"9557"	"ENSG00000131778"	"CHD1L"	"A5YM64; B4DDE1; B5MDZ7; hsa:9557; Q53EZ3; Q5VXX7; Q6DD94; Q6PK83; Q86WJ1; Q86XH3; Q96HF7; Q96SP3; Q9BVJ1; Q9NVV8"	"1q21.1 copy number variation syndrome; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"4"	"0"	"262.1"	"244.0"	"292.7"	"323.8"	"248.4"	"258.0"	"492.7"	"545.6"	"705.8"	"1610.8"	"2087.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06493"	"Cyclin-dependent kinase 1 OS=Homo sapiens OX=9606 GN=CDK1 PE=1 SV=3"	"0.000"	""	"13"	"3"	"6"	"2"	"297"	"34.1"	"8.40"	"1356.34"	"13.75"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"983"	"ENSG00000170312"	"CDK1"	"A8K7C4; C9J497; hsa:983; O60764; P06493"	"miRNA regulation of DNA damage response; Cell cycle; Microtubule cytoskeleton regulation; Spinal cord injury; Retinoblastoma gene in cancer; ATM signaling pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; ATM signaling in development and disease ; G1 to S cell cycle control; Cohesin complex - Cornelia de Lange syndrome; Urotensin-II-mediated signaling pathway; DNA damage response"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; Nuclear Pore Complex (NPC) Disassembly; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Regulation of TP53 Degradation; APC/C:Cdc20 mediated degradation of Cyclin B; Phosphorylation of the APC/C; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Transcriptional regulation by RUNX2; Ovarian tumor domain proteases; MASTL Facilitates Mitotic Progression; E2F-enabled inhibition of pre-replication complex formation; MAPK3 (ERK1) activation; Golgi Cisternae Pericentriolar Stack Reorganization; Condensation of Prophase Chromosomes; G1/S-Specific Transcription; Initiation of Nuclear Envelope (NE) Reformation; Condensation of Prometaphase Chromosomes; Activation of NIMA Kinases NEK9, NEK6, NEK7; G2/M DNA replication checkpoint; Depolymerization of the Nuclear Lamina; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1; Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes; Phosphorylation of Emi1"	"49"	"0"	"31.3"	"22.5"	"45.6"	"48.8"	"24.9"	"31.7"	"53.9"	"54.5"	"76.1"	"254.1"	"373.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43148"	"mRNA cap guanine-N7 methyltransferase OS=Homo sapiens OX=9606 GN=RNMT PE=1 SV=1"	"0.000"	""	"9"	"4"	"8"	"4"	"476"	"54.8"	"6.61"	"1505.23"	"13.71"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03291"	"8731"	"ENSG00000101654"	"RNMT"	"B0YJ90; D3DUJ5; hsa:8731; O43148; O94996; Q9UIJ9"	"mRNA processing; 15q25 copy number variation"	"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE"	"5"	"0"	"230.2"	"206.2"	"272.9"	"338.6"	"199.3"	"204.8"	"380.4"	"377.8"	"513.0"	"1068.4"	"1372.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99661"	"Kinesin-like protein KIF2C OS=Homo sapiens OX=9606 GN=KIF2C PE=1 SV=2"	"0.000"	""	"7"	"3"	"4"	"3"	"725"	"81.3"	"7.83"	"638.05"	"13.66"	"1"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"11004"	"ENSG00000142945"	"KIF2C"	"B3ITR9; hsa:11004; Q5JR88; Q6ICU1; Q96C18; Q96HB8; Q99661; Q9BWV8"	"Microtubule cytoskeleton regulation"	"Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"10"	"0"	"91.9"	"78.1"	"119.8"	"152.6"	"109.4"	"81.2"	"183.9"	"201.5"	"266.5"	"424.0"	"538.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23378"	"Glycine dehydrogenase (decarboxylating), mitochondrial OS=Homo sapiens OX=9606 GN=GLDC PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"1020"	"112.7"	"7.11"	"901.95"	"13.66"	"2"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01212, Pf02347"	"2731"	"ENSG00000178445"	"GLDC"	"hsa:2731; P23378; Q2M2F8"	"Metabolic Epileptic Disorders"	"Glycine degradation"	"2"	"0"	"73.7"	"62.4"	"75.9"	"77.4"	"61.7"	"69.7"	"146.6"	"180.3"	"268.3"	"522.4"	"750.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10606"	"Cytochrome c oxidase subunit 5B, mitochondrial OS=Homo sapiens OX=9606 GN=COX5B PE=1 SV=2"	"0.000"	""	"34"	"4"	"8"	"4"	"129"	"13.7"	"8.81"	"1406.62"	"13.66"	"4"	"4"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01215"	"1329"	"ENSG00000135940"	"COX5B"	"hsa:1329; P10606; Q53YB7; Q96J18; Q99610"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"225.4"	"210.8"	"217.0"	"288.1"	"170.6"	"182.9"	"288.5"	"310.8"	"403.9"	"1048.5"	"1544.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBS4"	"DnaJ homolog subfamily B member 11 OS=Homo sapiens OX=9606 GN=DNAJB11 PE=1 SV=1"	"0.000"	""	"17"	"4"	"6"	"4"	"358"	"40.5"	"6.18"	"1309.21"	"13.64"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00226, Pf01556"	"51726"	"ENSG00000090520"	"DNAJB11"	"hsa:51726; Q542Y5; Q542Y9; Q6IAQ8; Q96JC6; Q9UBS4"	"Photodynamic therapy-induced unfolded protein response"	"XBP1(S) activates chaperone genes"	"2"	"0"	"231.2"	"210.2"	"292.1"	"352.5"	"253.2"	"197.6"	"337.4"	"363.2"	"415.1"	"604.7"	"682.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60869"	"Endothelial differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDF1 PE=1 SV=1"	"0.000"	""	"21"	"3"	"8"	"3"	"148"	"16.4"	"9.95"	"2125.08"	"13.62"	"3"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01381, Pf08523"	"8721"	"ENSG00000107223"	"EDF1"	"hsa:8721; O60869; Q5T5T2; Q9UIM1"	""	""	"0"	"0"	"1102.0"	"1148.0"	"1027.9"	"1171.9"	"1010.0"	"1009.9"	"1243.1"	"1291.9"	"1382.4"	"1205.6"	"985.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16656"	"Nuclear respiratory factor 1 OS=Homo sapiens OX=9606 GN=NRF1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"5"	"2"	"503"	"53.5"	"5.05"	"1181.24"	"13.59"	"1"	"2"	"other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10491"	"4899"	"ENSG00000106459"	"NRF1"	"A8K4C6; B4DDV6; hsa:4899; Q15305; Q16656; Q96AN2"	"Energy metabolism; Interactions between LOXL4 and oxidative stress pathway; Mitochondrial gene expression; Sildenafil treatment"	"PPARA activates gene expression; Transcriptional activation of mitochondrial biogenesis"	"6"	"0"	"137.1"	"120.2"	"152.4"	"180.7"	"132.1"	"106.9"	"202.4"	"216.0"	"248.4"	"753.0"	"1575.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N163"	"Cell cycle and apoptosis regulator protein 2 OS=Homo sapiens OX=9606 GN=CCAR2 PE=1 SV=2"	"0.000"	""	"4"	"4"	"8"	"4"	"923"	"102.8"	"5.22"	"1276.82"	"13.59"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14443, Pf14444, Pf19256, Pf19257"	"57805"	"ENSG00000158941"	"CCAR2"	"A6NL03; B2RB79; D3DSR6; hsa:57805; Q6P0Q9; Q8N163; Q8N3G7; Q8N8M1; Q8TF34; Q9H9Q9; Q9HD12; Q9NT55"	"TAR syndrome"	"Regulation of HSF1-mediated heat shock response"	"2"	"0"	"305.1"	"295.3"	"354.6"	"460.8"	"307.3"	"312.7"	"477.3"	"481.4"	"520.0"	"889.5"	"1194.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62191"	"26S proteasome regulatory subunit 4 OS=Homo sapiens OX=9606 GN=PSMC1 PE=1 SV=1"	"0.000"	""	"14"	"4"	"7"	"4"	"440"	"49.2"	"6.21"	"1919.88"	"13.59"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5700"	"ENSG00000100764"	"PSMC1"	"B4DR63; hsa:5700; P49014; P62191; Q03527; Q6IAW0; Q6NW36; Q96AZ3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"64"	"0"	"137.0"	"117.0"	"160.0"	"186.7"	"133.8"	"130.0"	"204.5"	"213.7"	"275.6"	"731.1"	"1257.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46937"	"Transcriptional coactivator YAP1 OS=Homo sapiens OX=9606 GN=YAP1 PE=1 SV=2"	"0.000"	""	"11"	"4"	"6"	"4"	"504"	"54.4"	"5.17"	"646.44"	"13.57"	"2"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00397"	"10413"	"ENSG00000137693"	"YAP1"	"B4DTY1; B7ZA01; E3WEB5; E3WEB6; E9PRV2; F5H202; hsa:10413; K0KQ18; K0KYZ8; K0L195; K0L1G3; P46937; Q7Z574; Q8IUY9"	"Mesodermal commitment pathway; Mesodermal commitment pathway; RAC1/PAK1/p38/MMP2 pathway; miR-509-3p alteration of YAP1/ECM axis; Ciliary landscape; Leukocyte-intrinsic Hippo pathway functions; Netrin-UNC5B signaling pathway; Galanin receptor pathway; Pleural mesothelioma"	"Nuclear signaling by ERBB4; RUNX2 regulates osteoblast differentiation; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of axial mesoderm; Signaling by Hippo; YAP1- and WWTR1 (TAZ)-stimulated gene expression; EGR2 and SOX10-mediated initiation of Schwann cell myelination; RUNX3 regulates YAP1-mediated transcription"	"17"	"0"	"227.7"	"187.5"	"262.0"	"271.2"	"214.7"	"225.4"	"269.9"	"273.6"	"311.5"	"590.7"	"821.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96Q89"	"Kinesin-like protein KIF20B OS=Homo sapiens OX=9606 GN=KIF20B PE=1 SV=3"	"0.000"	""	"3"	"3"	"6"	"3"	"1820"	"210.5"	"5.67"	"1200.86"	"13.56"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"9585"	"ENSG00000138182"	"KIF20B"	"A8MXM7; hsa:9585; O43277; Q09471; Q2KQ73; Q32NE1; Q561V3; Q58EX8; Q5T9M8; Q5T9M9; Q5T9N0; Q5T9N1; Q7KZ68; Q7Z5E0; Q7Z5E1; Q7Z6M9; Q86X82; Q96Q89; Q9H3R8; Q9H6Q9; Q9H755; Q9NTC1; Q9UFR5"	"Gastric cancer network 1"	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"3"	"0"	"106.2"	"94.7"	"105.9"	"117.0"	"98.8"	"99.1"	"136.5"	"135.8"	"163.3"	"266.7"	"306.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1N9"	"Putative deoxyribonuclease TATDN1 OS=Homo sapiens OX=9606 GN=TATDN1 PE=1 SV=2"	"0.000"	""	"12"	"4"	"9"	"4"	"297"	"33.6"	"6.96"	"1400.11"	"13.55"	"4"	"4"	"DNA metabolism"	"nucleus"	"other molecular function"	"Pf01026"	"83940"	"ENSG00000147687"	"TATDN1"	"B2R5J0; hsa:83940; Q6P1N9; Q8TD02; Q9BY40"	""	""	"0"	"0"	"60.1"	"46.8"	"68.0"	"100.6"	"70.1"	"194.8"	"117.1"	"145.7"	"201.3"	"734.2"	"785.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29590"	"Protein PML OS=Homo sapiens OX=9606 GN=PML PE=1 SV=3"	"0.000"	""	"7"	"4"	"7"	"4"	"882"	"97.5"	"6.21"	"1023.94"	"13.54"	"3"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00643, Pf12126"	"5371"	"ENSG00000140464"	"PML"	"E9PBR7; hsa:5371; P29590; P29591; P29592; P29593; Q00755; Q15959; Q59FP9; Q8WUA0; Q96S41; Q9BPW2; Q9BWP7; Q9BZX6; Q9BZX7; Q9BZX8; Q9BZX9; Q9BZY0; Q9BZY2; Q9BZY3"	"miRNA regulation of DNA damage response; Wnt/beta-catenin signaling pathway in leukemia; p53 transcriptional gene network; DNA damage response"	"Regulation of PTEN localization; Interferon gamma signaling; HCMV Early Events; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Regulation of TP53 Activity through Acetylation; Regulation of RUNX1 Expression and Activity"	"11"	"0"	"198.9"	"183.4"	"206.5"	"295.6"	"189.8"	"165.7"	"282.0"	"283.0"	"346.4"	"637.3"	"890.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZT3"	"SRA stem-loop-interacting RNA-binding protein, mitochondrial OS=Homo sapiens OX=9606 GN=SLIRP PE=1 SV=1"	"0.000"	""	"33"	"3"	"6"	"3"	"109"	"12.3"	"10.24"	"1256.80"	"13.51"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	""	"Pf00076"	"81892"	"ENSG00000119705"	"SLIRP"	"hsa:81892; J3KMY7; Q9GZT3"	""	""	"0"	"0"	"212.7"	"162.7"	"279.1"	"431.7"	"219.6"	"198.2"	"363.9"	"400.5"	"518.3"	"1182.0"	"1666.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEE9"	"Craniofacial development protein 1 OS=Homo sapiens OX=9606 GN=CFDP1 PE=1 SV=1"	"0.000"	""	"20"	"5"	"8"	"5"	"299"	"33.6"	"4.81"	"1639.33"	"13.49"	"4"	"4"	"cell adhesion;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf07572"	"10428"	"ENSG00000153774"	"CFDP1"	"hsa:10428; O00393; O00404; Q9UEE9; Q9UEF0; Q9UEF1; Q9UEF8"	""	""	"0"	"0"	"420.4"	"388.1"	"454.6"	"512.1"	"397.1"	"425.7"	"533.3"	"522.7"	"642.5"	"1099.4"	"1429.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75052"	"Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein OS=Homo sapiens OX=9606 GN=NOS1AP PE=1 SV=3"	"0.000"	""	"10"	"3"	"5"	"3"	"506"	"56.1"	"6.30"	"850.82"	"13.48"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00640"	"9722"	"ENSG00000198929"	"NOS1AP"	"B7ZLF5; hsa:9722; O43564; O75052; Q3T551; Q5VU95"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"187.1"	"170.3"	"178.6"	"212.2"	"154.9"	"163.3"	"250.4"	"254.3"	"366.7"	"708.6"	"848.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92797"	"Symplekin OS=Homo sapiens OX=9606 GN=SYMPK PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1274"	"141.1"	"6.13"	"1662.01"	"13.47"	"3"	"3"	"cell adhesion;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf11935, Pf12295"	"8189"	"ENSG00000125755"	"SYMPK"	"hsa:8189; O00521; O00689; O00733; Q59GT5; Q8N2U5; Q92797"	""	"Transport of Mature mRNA Derived from an Intronless Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"76.0"	"60.7"	"93.8"	"98.0"	"60.5"	"73.4"	"144.3"	"138.4"	"212.6"	"584.2"	"818.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HS1"	"Serine/threonine-protein phosphatase PGAM5, mitochondrial OS=Homo sapiens OX=9606 GN=PGAM5 PE=1 SV=2"	"0.000"	""	"13"	"3"	"8"	"3"	"289"	"32.0"	"8.68"	"1588.57"	"13.46"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"enzyme regulator activity;other molecular function"	"Pf00300"	"192111"	"ENSG00000247077"	"PGAM5"	"A9LN06; C9IZY7; hsa:192111; Q96HS1; Q96JB0"	"NRF2-ARE regulation"	""	"1"	"0"	"121.9"	"119.7"	"159.9"	"199.3"	"130.7"	"125.7"	"228.2"	"245.9"	"346.7"	"869.9"	"1326.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76094"	"Signal recognition particle subunit SRP72 OS=Homo sapiens OX=9606 GN=SRP72 PE=1 SV=3"	"0.000"	""	"6"	"3"	"6"	"3"	"671"	"74.6"	"9.26"	"638.22"	"13.46"	"1"	"3"	"transport"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08492, Pf13181, Pf17004"	"6731"	"ENSG00000174780"	"SRP72"	"G5E9Z8; hsa:6731; O76094; Q7Z3C0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"53.5"	"58.5"	"89.2"	"120.5"	"74.5"	"63.7"	"128.8"	"121.9"	"176.0"	"562.1"	"1114.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62875"	"DNA-directed RNA polymerases I, II, and III subunit RPABC5 OS=Homo sapiens OX=9606 GN=POLR2L PE=1 SV=1"	"0.000"	""	"60"	"3"	"4"	"3"	"67"	"7.6"	"7.77"	"415.21"	"13.44"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01194"	"5441"	"ENSG00000177700"	"POLR2L"	"hsa:5441; P52436; P62875; Q6FHX3"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"mRNA Splicing - Major Pathway; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"56"	"0"	"51.1"	"44.6"	"54.4"	"83.8"	"45.8"	"49.7"	"113.9"	"118.8"	"191.0"	"408.9"	"532.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VT52"	"Regulation of nuclear pre-mRNA domain-containing protein 2 OS=Homo sapiens OX=9606 GN=RPRD2 PE=1 SV=1"	"0.000"	""	"4"	"4"	"7"	"4"	"1461"	"155.9"	"7.42"	"972.97"	"13.35"	"3"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf04818"	"23248"	"ENSG00000163125"	"RPRD2"	"A8K6N8; B3KPT1; B4E2Q6; hsa:23248; O75048; Q5VT51; Q5VT52; Q5VT53; Q6MZL4; Q86XD2; Q9P0D7"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"171.2"	"141.4"	"188.2"	"221.6"	"145.2"	"154.8"	"250.7"	"238.4"	"274.9"	"523.0"	"813.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22314"	"Ubiquitin-like modifier-activating enzyme 1 OS=Homo sapiens OX=9606 GN=UBA1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"8"	"2"	"1058"	"117.8"	"5.76"	"1462.83"	"13.34"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00899, Pf09358, Pf10585, Pf16190, Pf16191"	"7317"	"ENSG00000130985"	"UBA1"	"hsa:7317; P22314; Q5JRR8; Q96E13"	"Proteasome degradation; Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Antigen processing: Ubiquitination & Proteasome degradation"	"5"	"0"	"118.7"	"120.4"	"200.7"	"418.3"	"105.5"	"113.8"	"222.6"	"239.2"	"254.9"	"650.8"	"1824.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49327"	"Fatty acid synthase OS=Homo sapiens OX=9606 GN=FASN PE=1 SV=3"	"0.000"	""	"3"	"4"	"7"	"4"	"2511"	"273.3"	"6.44"	"1105.99"	"13.27"	"3"	"4"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00107, Pf00109, Pf00550, Pf00698, Pf00975, Pf02801, Pf08242, Pf08659, Pf14765, Pf16197"	"2194"	"ENSG00000169710"	"FASN"	"hsa:2194; P49327; Q13479; Q16702; Q4LE83; Q6P4U5; Q6SS02; Q969R1; Q96C68; Q96IT0"	"AMP-activated protein kinase signaling; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Liver X receptor pathway; Nuclear receptors meta-pathway; Fatty acid biosynthesis; Angiopoietin-like protein 8 regulatory pathway; Lipid metabolism pathway; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-9 fatty acid synthesis; FOXA2 pathway"	"ChREBP activates metabolic gene expression; Activation of gene expression by SREBF (SREBP); Fatty acyl-CoA biosynthesis; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; Vitamin B5 (pantothenate) metabolism"	"18"	"0"	"32.6"	"40.8"	"41.5"	"63.8"	"31.4"	"28.6"	"62.8"	"76.3"	"71.9"	"190.9"	"275.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6E0"	"Serine/threonine-protein kinase 24 OS=Homo sapiens OX=9606 GN=STK24 PE=1 SV=1"	"0.000"	""	"8"	"3"	"8"	"3"	"443"	"49.3"	"5.69"	"1213.83"	"13.27"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"8428"	"ENSG00000102572"	"STK24"	"hsa:8428; O14840; Q5JV92; Q9Y6E0"	""	"Apoptotic cleavage of cellular proteins"	"2"	"0"	"257.6"	"227.5"	"312.9"	"339.1"	"225.3"	"233.1"	"363.3"	"384.4"	"479.7"	"1191.5"	"2461.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK61"	"Protein TASOR OS=Homo sapiens OX=9606 GN=TASOR PE=1 SV=3"	"0.000"	""	"4"	"5"	"10"	"5"	"1670"	"188.9"	"5.80"	"2307.50"	"13.23"	"5"	"4"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12509"	"23272"	"ENSG00000163946"	"TASOR"	"A1L3A4; B5ME28; hsa:23272; Q9H2F7; Q9UK61; Q9UPP7"	""	""	"0"	"0"	"282.7"	"261.6"	"315.8"	"347.1"	"251.6"	"234.3"	"381.4"	"441.5"	"549.6"	"1195.1"	"1610.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRN9"	"rRNA N6-adenosine-methyltransferase METTL5 OS=Homo sapiens OX=9606 GN=METTL5 PE=1 SV=1"	"0.000"	""	"15"	"3"	"8"	"3"	"209"	"23.7"	"6.68"	"1362.41"	"13.23"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05175"	"29081"	"ENSG00000138382"	"METTL5"	"D3DPC9; hsa:29081; Q9NRN9; Q9NVX1"	""	""	"0"	"0"	"91.6"	"70.9"	"111.1"	"113.2"	"92.6"	"96.6"	"215.6"	"225.1"	"379.5"	"1117.7"	"1541.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60520"	"Gamma-aminobutyric acid receptor-associated protein-like 2 OS=Homo sapiens OX=9606 GN=GABARAPL2 PE=1 SV=1"	"0.000"	""	"32"	"4"	"7"	"3"	"117"	"13.7"	"8.10"	"1093.16"	"13.22"	"3"	"4"	"cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11345"	"ENSG00000034713"	"GABARAPL2"	"hsa:11345; O08765; P60520; Q6FG91; Q9DCP8; Q9UQF7"	"Network map of SARS-CoV-2 signaling pathway; 2q37 copy number variation syndrome"	"Macroautophagy; TBC/RABGAPs"	"4"	"1"	"227.3"	"200.3"	"263.0"	"315.9"	"219.3"	"223.2"	"601.8"	"658.7"	"1153.6"	"3715.4"	"4555.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSD9"	"Phenylalanine--tRNA ligase beta subunit OS=Homo sapiens OX=9606 GN=FARSB PE=1 SV=3"	"0.000"	""	"9"	"4"	"8"	"4"	"589"	"66.1"	"6.84"	"1297.35"	"13.22"	"4"	"4"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03483, Pf03484, Pf17759, Pf18262"	"10056"	"ENSG00000116120"	"FARSB"	"B4DFM0; hsa:10056; O95708; Q4ZFX1; Q57ZJ5; Q9NSD9; Q9NZZ6"	"VEGFA-VEGFR2 signaling; Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"3"	"0"	"156.1"	"148.6"	"210.5"	"242.5"	"146.3"	"150.4"	"277.7"	"288.5"	"353.3"	"677.6"	"756.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPT5"	"Exocyst complex component 7 OS=Homo sapiens OX=9606 GN=EXOC7 PE=1 SV=3"	"0.000"	""	"6"	"4"	"7"	"4"	"735"	"83.3"	"6.79"	"1725.64"	"13.17"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03081"	"23265"	"ENSG00000182473"	"EXOC7"	"B5MC69; B8XXP2; hsa:23265; Q8ND93; Q8WV91; Q96FF0; Q9H8C3; Q9H9X3; Q9HA32; Q9UPT5"	"Angiopoietin-like protein 8 regulatory pathway; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"5"	"0"	"104.4"	"86.1"	"147.9"	"151.8"	"108.0"	"124.4"	"356.8"	"414.6"	"685.8"	"1249.3"	"1458.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXT5"	"RNA-binding protein 12B OS=Homo sapiens OX=9606 GN=RBM12B PE=1 SV=2"	"0.001"	""	"5"	"3"	"4"	"3"	"1001"	"118.0"	"6.81"	"239.44"	"13.15"	"1"	"3"	"other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"389677"	"ENSG00000183808"	"RBM12B"	"A8MYB5; hsa:389677; Q8IXT5"	""	""	"0"	"0"	"84.1"	"75.7"	"127.8"	"158.1"	"84.1"	"88.3"	"151.8"	"158.2"	"220.5"	"582.9"	"977.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEW8"	"STE20/SPS1-related proline-alanine-rich protein kinase OS=Homo sapiens OX=9606 GN=STK39 PE=1 SV=3"	"0.000"	""	"6"	"2"	"7"	"1"	"545"	"59.4"	"6.29"	"1054.93"	"13.13"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12202"	"27347"	"ENSG00000198648"	"STK39"	"hsa:27347; O14774; Q53S90; Q53SL7; Q53SS1; Q9UER4; Q9UEW8; X5D9C8"	""	""	"0"	"0"	"5.6"	"4.4"	"7.5"	"8.8"	"7.9"	"6.7"	"9.9"	"9.8"	"14.6"	"55.9"	"54.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35268"	"60S ribosomal protein L22 OS=Homo sapiens OX=9606 GN=RPL22 PE=1 SV=2"	"0.000"	""	"42"	"3"	"4"	"3"	"128"	"14.8"	"9.19"	"492.54"	"13.12"	"1"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01776"	"6146"	"ENSG00000116251"	"RPL22"	"B2R495; hsa:6146; P35268; Q6IBD1"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"266.4"	"262.0"	"291.0"	"312.4"	"266.6"	"268.3"	"257.6"	"278.5"	"253.7"	"259.5"	"312.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14818"	"Proteasome subunit alpha type-7 OS=Homo sapiens OX=9606 GN=PSMA7 PE=1 SV=1"	"0.000"	""	"12"	"4"	"8"	"4"	"248"	"27.9"	"8.46"	"1426.86"	"13.09"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5688"	"ENSG00000101182"	"PSMA7"	"B2R515; hsa:5688; O14818; Q5JXJ2; Q9BR53; Q9H4K5; Q9UEU8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"234.5"	"256.7"	"301.9"	"431.9"	"227.7"	"260.0"	"482.9"	"514.6"	"706.9"	"1661.9"	"2921.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C005"	"Protein dpy-30 homolog OS=Homo sapiens OX=9606 GN=DPY30 PE=1 SV=1"	"0.000"	""	"27"	"3"	"8"	"3"	"99"	"11.2"	"4.88"	"1366.45"	"13.09"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"ER/Golgi;nucleus"	"other molecular function"	"Pf05186"	"84661"	"ENSG00000162961"	"DPY30"	"D6W578; hsa:84661; Q9C005"	"Kleefstra syndrome"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes"	"5"	"0"	"62.8"	"47.6"	"86.7"	"96.0"	"57.9"	"83.3"	"116.7"	"119.3"	"205.9"	"728.3"	"1090.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2L5"	"Trafficking protein particle complex subunit 8 OS=Homo sapiens OX=9606 GN=TRAPPC8 PE=1 SV=2"	""	""	"4"	"3"	"3"	"3"	"1435"	"160.9"	"6.87"	""	"13.08"	""	"3"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	""	"Pf12739"	"22878"	"ENSG00000153339"	"TRAPPC8"	"A0JP15; B3KME5; hsa:22878; Q9H0L2; Q9Y2L5"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"11.2"	"10.8"	"12.5"	"15.6"	"13.2"	"12.7"	"42.6"	"53.1"	"96.0"	"312.7"	"549.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62847"	"40S ribosomal protein S24 OS=Homo sapiens OX=9606 GN=RPS24 PE=1 SV=1"	"0.000"	""	"11"	"2"	"7"	"2"	"133"	"15.4"	"10.78"	"1206.75"	"13.07"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01282"	"6229"	"ENSG00000138326"	"RPS24"	"E7EPK6; hsa:6229; P16632; P62847; Q5T0P7; Q5T0P8; Q7Z3D1"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"102.2"	"92.5"	"146.4"	"235.4"	"100.6"	"103.6"	"223.2"	"235.8"	"371.4"	"895.2"	"1640.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13330"	"Metastasis-associated protein MTA1 OS=Homo sapiens OX=9606 GN=MTA1 PE=1 SV=2"	"0.000"	""	"8"	"5"	"9"	"5"	"715"	"80.7"	"9.26"	"1756.39"	"13.06"	"5"	"4"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf00320, Pf01426, Pf01448, Pf17226"	"9112"	"ENSG00000182979"	"MTA1"	"A5PLK4; hsa:9112; Q13330; Q86SW2; Q8NFI8; Q96GI8"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; TAR syndrome"	"Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; SUMOylation of transcription factors"	"8"	"0"	"239.0"	"212.0"	"263.7"	"343.6"	"219.3"	"239.1"	"390.6"	"413.8"	"515.9"	"1347.5"	"1928.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q52LJ0"	"Protein FAM98B OS=Homo sapiens OX=9606 GN=FAM98B PE=1 SV=2"	"0.000"	""	"6"	"2"	"6"	"1"	"433"	"45.5"	"8.69"	"1179.68"	"13.06"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"283742"	"ENSG00000171262"	"FAM98B"	"A8MUW5; hsa:283742; Q52LJ0; Q8N935"	""	"tRNA processing in the nucleus"	"1"	"0"	"76.5"	"89.0"	"84.8"	"90.0"	"70.9"	"86.1"	"115.1"	"104.4"	"95.3"	"217.0"	"302.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HC4"	"PDZ and LIM domain protein 5 OS=Homo sapiens OX=9606 GN=PDLIM5 PE=1 SV=5"	"0.000"	""	"5"	"2"	"6"	"2"	"596"	"63.9"	"8.21"	"1357.95"	"13.05"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"10611"	"ENSG00000163110"	"PDLIM5"	"A8K6F9; D6RB78; E9PBF5; hsa:10611; O60705; Q56VN4; Q5UW38; Q8WVK0; Q96HC4"	"Extracellular vesicles in the crosstalk of cardiac cells"	"Neurexins and neuroligins"	"2"	"0"	"192.1"	"179.3"	"223.7"	"273.8"	"180.2"	"207.1"	"331.9"	"325.0"	"438.1"	"1011.7"	"1664.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A0FGR8"	"Extended synaptotagmin-2 OS=Homo sapiens OX=9606 GN=ESYT2 PE=1 SV=1"	"0.000"	""	"4"	"3"	"8"	"3"	"921"	"102.3"	"9.26"	"1285.59"	"13.04"	"3"	"3"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00168, Pf17047"	"57488"	"ENSG00000117868"	"ESYT2"	"A0FGR8; A4D229; hsa:57488; Q69YJ2; Q6UKI4; Q6ZTU0; Q6ZVU1; Q9BQS0; Q9NW47; Q9ULJ2"	""	"Glycosphingolipid metabolism"	"1"	"0"	"21.2"	"17.7"	"35.8"	"43.6"	"44.4"	"106.9"	"228.2"	"245.3"	"321.1"	"267.0"	"222.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62277"	"40S ribosomal protein S13 OS=Homo sapiens OX=9606 GN=RPS13 PE=1 SV=2"	"0.000"	""	"32"	"6"	"11"	"6"	"151"	"17.2"	"10.54"	"2009.73"	"13.03"	"5"	"5"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00312, Pf08069"	"6207"	"ENSG00000110700"	"RPS13"	"B2R549; hsa:6207; P19116; P62277; Q02546; Q29200; Q498Y0"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"590.0"	"647.0"	"722.2"	"924.6"	"568.1"	"591.5"	"1019.7"	"1013.0"	"1195.6"	"2550.3"	"3687.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49755"	"Transmembrane emp24 domain-containing protein 10 OS=Homo sapiens OX=9606 GN=TMED10 PE=1 SV=2"	"0.000"	""	"17"	"3"	"4"	"3"	"219"	"25.0"	"7.44"	"536.48"	"13.02"	"1"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf01105"	"10972"	"ENSG00000170348"	"TMED10"	"B2R605; hsa:10972; P49755; Q15602; Q16536; Q86TC2; Q86TS5"	"mRNA processing; 5q35 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Cargo concentration in the ER"	"6"	"0"	"45.9"	"46.0"	"70.5"	"74.4"	"35.9"	"43.2"	"111.3"	"122.9"	"205.2"	"846.0"	"1374.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95229"	"ZW10 interactor OS=Homo sapiens OX=9606 GN=ZWINT PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"2"	"277"	"31.3"	"5.15"	"407.03"	"13.02"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15556"	"11130"	"ENSG00000122952"	"ZWINT"	"A6NNV6; hsa:11130; O95229; Q0D2I3; Q9BWD0"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"17.4"	"12.7"	"16.8"	"21.9"	"14.6"	"13.5"	"41.0"	"46.5"	"77.5"	"152.9"	"163.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02533"	"Keratin, type I cytoskeletal 14 OS=Homo sapiens OX=9606 GN=KRT14 PE=1 SV=4"	"0.000"	""	"7"	"5"	"10"	"1"	"472"	"51.5"	"5.16"	"2093.30"	"13.02"	"5"	"4"	"cell organization and biogenesis;other biological processes"	"plasma membrane;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00038"	"3861"	"ENSG00000186847"	"KRT14"	"hsa:3861; P02533; Q14715; Q53XY3; Q9BUE3; Q9UBN2; Q9UBN3; Q9UCY4"	"Corticotropin-releasing hormone signaling pathway"	"Formation of the cornified envelope; Type I hemidesmosome assembly"	"4"	"0"	"53.0"	"105.9"	"491.6"	"36.3"	"3.6"	"37.1"	"171.0"	"126.4"	"108.2"	"114.0"	"158.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2K3"	"REST corepressor 3 OS=Homo sapiens OX=9606 GN=RCOR3 PE=1 SV=2"	"0.000"	""	"10"	"3"	"7"	"2"	"495"	"55.5"	"8.27"	"1697.93"	"12.97"	"3"	"2"	"other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00249, Pf01448"	"55758"	"ENSG00000117625"	"RCOR3"	"B3KYA2; B4DYY7; hsa:55758; Q5VT47; Q7L9I5; Q8N5U3; Q9NV83; Q9P2K3"	""	""	"0"	"1"	"51.0"	"44.0"	"60.2"	"59.6"	"53.4"	"46.4"	"79.4"	"85.3"	"108.6"	"353.2"	"619.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96000"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 10 OS=Homo sapiens OX=9606 GN=NDUFB10 PE=1 SV=3"	"0.000"	""	"23"	"3"	"7"	"3"	"172"	"20.8"	"8.48"	"881.59"	"12.95"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10249"	"4716"	"ENSG00000140990"	"NDUFB10"	"hsa:4716; O96000; Q96II6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Modulators of TCR signaling and T cell activation; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"56.4"	"56.4"	"75.7"	"96.4"	"57.8"	"70.0"	"138.5"	"158.7"	"266.8"	"622.4"	"729.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UK45"	"U6 snRNA-associated Sm-like protein LSm7 OS=Homo sapiens OX=9606 GN=LSM7 PE=1 SV=1"	"0.000"	""	"64"	"4"	"5"	"4"	"103"	"11.6"	"5.27"	"542.73"	"12.93"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51690"	"ENSG00000130332"	"LSM7"	"hsa:51690; Q9UK45"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"258.6"	"222.9"	"299.4"	"410.2"	"238.9"	"256.4"	"399.4"	"377.6"	"470.9"	"1384.7"	"2686.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92665"	"28S ribosomal protein S31, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS31 PE=1 SV=3"	"0.000"	""	"16"	"5"	"9"	"5"	"395"	"45.3"	"9.29"	"1420.48"	"12.89"	"4"	"5"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf15433"	"10240"	"ENSG00000102738"	"MRPS31"	"B2RCS3; hsa:10240; Q5VYC8; Q8WTV8; Q92665"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"459.3"	"436.6"	"489.6"	"541.6"	"435.2"	"467.6"	"639.7"	"667.6"	"820.0"	"1500.9"	"2010.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P47985"	"Cytochrome b-c1 complex subunit Rieske, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRFS1 PE=1 SV=2"	""	""	"22"	"4"	"4"	"4"	"274"	"29.6"	"8.32"	""	"12.88"	""	"4"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00355, Pf02921, Pf09165"	"7386"	"ENSG00000169021"	"UQCRFS1"	"A8K519; hsa:7386; P47985; Q6NVX5; Q9UPH2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly; Iron metabolism disorders; Arsenic metabolism and reactive oxygen species generation"	"Respiratory electron transport"	"6"	"0"	"356.6"	"334.0"	"383.2"	"587.4"	"283.2"	"316.5"	"481.1"	"514.6"	"631.8"	"1090.9"	"1342.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UB35"	"Monofunctional C1-tetrahydrofolate synthase, mitochondrial OS=Homo sapiens OX=9606 GN=MTHFD1L PE=1 SV=1"	"0.000"	""	"3"	"2"	"6"	"2"	"978"	"105.7"	"8.06"	"1453.03"	"12.87"	"2"	"2"	"other metabolic processes;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00763, Pf01268, Pf02882"	"25902"	"ENSG00000120254"	"MTHFD1L"	"hsa:25902; Q2TBF3; Q6UB35; Q8WVW0; Q96HG8; Q9H789; Q9UFU8"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways"	"Metabolism of folate and pterines"	"3"	"0"	"117.5"	"92.8"	"108.7"	"144.2"	"87.2"	"72.2"	"177.1"	"177.6"	"277.2"	"842.4"	"1088.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09884"	"DNA polymerase alpha catalytic subunit OS=Homo sapiens OX=9606 GN=POLA1 PE=1 SV=2"	"0.000"	""	"3"	"4"	"6"	"4"	"1462"	"165.8"	"5.85"	"705.13"	"12.82"	"2"	"4"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08996, Pf12254"	"5422"	"ENSG00000101868"	"POLA1"	"hsa:5422; P09884; Q86UQ7"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication"	"Activation of the pre-replicative complex; Defective pyroptosis; G1/S-Specific Transcription; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"13"	"0"	"113.7"	"95.8"	"144.5"	"153.8"	"117.0"	"111.5"	"247.0"	"261.2"	"441.3"	"1802.6"	"2175.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96019"	"Actin-like protein 6A OS=Homo sapiens OX=9606 GN=ACTL6A PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"429"	"47.4"	"5.60"	"1160.51"	"12.82"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00022"	"86"	"ENSG00000136518"	"ACTL6A"	"B3KMN1; D3DNR9; hsa:86; O96019; Q8TAE5; Q9BVS8; Q9H0W6"	"Androgen receptor network in prostate cancer; Gastric cancer network 1; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"UCH proteinases; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines; HATs acetylate histones; DNA Damage Recognition in GG-NER"	"10"	"0"	"129.6"	"140.1"	"173.3"	"283.6"	"141.0"	"155.2"	"226.7"	"227.1"	"267.4"	"636.7"	"1039.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14802"	"DNA-directed RNA polymerase III subunit RPC1 OS=Homo sapiens OX=9606 GN=POLR3A PE=1 SV=2"	"0.000"	""	"2"	"4"	"8"	"3"	"1390"	"155.5"	"8.48"	"1326.56"	"12.79"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00623, Pf04983, Pf04997, Pf04998, Pf05000"	"11128"	"ENSG00000148606"	"POLR3A"	"hsa:11128; O14802; Q8IW34; Q8TCW5"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"9"	"0"	"88.5"	"67.2"	"91.3"	"128.7"	"93.6"	"83.1"	"134.3"	"153.8"	"218.1"	"480.9"	"770.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZJ9"	"Diphosphoinositol polyphosphate phosphohydrolase 2 OS=Homo sapiens OX=9606 GN=NUDT4 PE=1 SV=2"	"0.000"	""	"17"	"5"	"8"	"2"	"180"	"20.3"	"6.35"	"1432.14"	"12.79"	"4"	"4"	"other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11163"	"ENSG00000173598"	"NUDT4"	"B7Z916; hsa:11163; Q4AEJ6; Q53EZ2; Q68DD7; Q9NPC5; Q9NS30; Q9NZJ9; Q9NZK0; Q9NZK1"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"81.5"	"71.5"	"116.9"	"146.0"	"134.7"	"211.6"	"426.6"	"455.5"	"512.0"	"869.3"	"1087.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02809"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 1 OS=Homo sapiens OX=9606 GN=PLOD1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"727"	"83.5"	"6.95"	"1218.96"	"12.75"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf03171"	"5351"	"ENSG00000083444"	"PLOD1"	"B4DR87; hsa:5351; Q02809; Q96AV9; Q9H132"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"130.1"	"92.3"	"145.9"	"174.9"	"123.9"	"136.3"	"184.9"	"211.6"	"272.5"	"706.3"	"1255.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZZ1"	"N-alpha-acetyltransferase 50 OS=Homo sapiens OX=9606 GN=NAA50 PE=1 SV=1"	"0.000"	""	"21"	"3"	"6"	"3"	"169"	"19.4"	"8.81"	"1146.45"	"12.71"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"80218"	"ENSG00000121579"	"NAA50"	"D3DN74; hsa:80218; Q68DQ1; Q9GZZ1"	"Metapathway biotransformation Phase I and II"	""	"1"	"0"	"87.4"	"67.0"	"95.2"	"115.1"	"83.6"	"79.9"	"215.6"	"238.0"	"469.9"	"1595.8"	"1558.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46100"	"Transcriptional regulator ATRX OS=Homo sapiens OX=9606 GN=ATRX PE=1 SV=5"	"0.000"	""	"2"	"3"	"5"	"3"	"2492"	"282.4"	"6.58"	"635.78"	"12.65"	"2"	"3"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"120.3"	"108.4"	"141.5"	"162.9"	"132.6"	"110.6"	"181.2"	"208.6"	"268.6"	"864.2"	"1298.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y237"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 4 OS=Homo sapiens OX=9606 GN=PIN4 PE=1 SV=1"	"0.000"	""	"31"	"4"	"8"	"4"	"131"	"13.8"	"9.77"	"1225.05"	"12.63"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13616"	"5303"	"ENSG00000102309"	"PIN4"	"A8E0G6; B3KXM0; F5H1P5; hsa:5303; Q0D2H3; Q3MHV0; Q52M21; Q5HYW6; Q6IRW4; Q9Y237"	""	""	"0"	"0"	"390.7"	"450.7"	"525.9"	"727.5"	"554.8"	"398.0"	"741.2"	"764.9"	"911.7"	"1473.1"	"1544.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60884"	"DnaJ homolog subfamily A member 2 OS=Homo sapiens OX=9606 GN=DNAJA2 PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"3"	"412"	"45.7"	"6.48"	"782.20"	"12.60"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;other cell component"	"other molecular function"	"Pf00226, Pf00684, Pf01556"	"10294"	"ENSG00000069345"	"DNAJA2"	"B2R7L7; hsa:10294; O14711; O60884"	""	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand"	"1"	"0"	"95.8"	"97.7"	"101.6"	"118.5"	"89.8"	"100.1"	"153.3"	"162.8"	"220.9"	"463.8"	"610.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Q3"	"Glutathione S-transferase kappa 1 OS=Homo sapiens OX=9606 GN=GSTK1 PE=1 SV=3"	"0.000"	""	"19"	"3"	"6"	"3"	"226"	"25.5"	"8.41"	"1202.98"	"12.57"	"3"	"3"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf01323"	"373156"	"ENSG00000197448"	"GSTK1"	"B4DIH1; B4DSY2; hsa:373156; Q6P4H0; Q7Z520; Q9P1S4; Q9Y2Q3"	"Metapathway biotransformation Phase I and II"	"Peroxisomal protein import; Glutathione conjugation"	"3"	"0"	"52.1"	"38.4"	"76.5"	"90.7"	"54.6"	"63.1"	"140.9"	"175.9"	"318.5"	"1035.3"	"1397.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVY7"	"Ubiquitin-like domain-containing CTD phosphatase 1 OS=Homo sapiens OX=9606 GN=UBLCP1 PE=1 SV=2"	"0.000"	""	"17"	"4"	"6"	"4"	"318"	"36.8"	"6.46"	"1327.50"	"12.57"	"3"	"3"	"protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00240, Pf03031"	"134510"	"ENSG00000164332"	"UBLCP1"	"D3DQJ7; hsa:134510; Q8WVY7; Q96DK5"	""	""	"0"	"0"	"53.5"	"40.3"	"74.0"	"100.5"	"55.7"	"59.8"	"248.2"	"254.2"	"551.2"	"1847.9"	"2053.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPJ3"	"Acyl-coenzyme A thioesterase 13 OS=Homo sapiens OX=9606 GN=ACOT13 PE=1 SV=1"	"0.000"	""	"18"	"2"	"6"	"2"	"140"	"15.0"	"9.14"	"1386.03"	"12.54"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf03061"	"55856"	"ENSG00000112304"	"ACOT13"	"F5H2L4; hsa:55856; O95549; Q9NPJ3"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"74.9"	"59.4"	"89.9"	"109.9"	"78.9"	"74.1"	"156.6"	"153.2"	"257.3"	"580.7"	"866.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04760"	"Lactoylglutathione lyase OS=Homo sapiens OX=9606 GN=GLO1 PE=1 SV=4"	"0.000"	""	"29"	"4"	"8"	"4"	"184"	"20.8"	"5.31"	"1608.39"	"12.48"	"4"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00903"	"2739"	"ENSG00000124767"	"GLO1"	"B2R6P7; B4DDV0; hsa:2739; P78375; Q04760; Q59EL0; Q5TZW3; Q96FC0; Q96J41"	""	"Pyruvate metabolism"	"1"	"0"	"153.3"	"189.7"	"261.3"	"541.9"	"142.6"	"125.6"	"309.5"	"353.0"	"409.6"	"807.8"	"925.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19404"	"NADH dehydrogenase [ubiquinone] flavoprotein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFV2 PE=1 SV=2"	"0.000"	""	"12"	"3"	"7"	"3"	"249"	"27.4"	"8.06"	"810.49"	"12.46"	"2"	"3"	"other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01257"	"4729"	"ENSG00000178127"	"NDUFV2"	"hsa:4729; P19404; Q9BV41"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"82.8"	"79.3"	"94.1"	"103.2"	"100.9"	"93.3"	"151.1"	"153.6"	"239.8"	"530.4"	"627.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A33"	"Coiled-coil domain-containing protein 47 OS=Homo sapiens OX=9606 GN=CCDC47 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"483"	"55.8"	"4.87"	"709.82"	"12.44"	"2"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"translation activity;other molecular function"	"Pf07946"	"57003"	"ENSG00000108588"	"CCDC47"	"B2RAS8; D3DU20; hsa:57003; Q96A33; Q96D00; Q96JZ7; Q9H3E4; Q9NRG3"	""	""	"0"	"0"	"117.7"	"95.2"	"124.9"	"118.1"	"100.4"	"109.6"	"178.7"	"192.7"	"267.8"	"895.2"	"1396.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42696"	"RNA-binding protein 34 OS=Homo sapiens OX=9606 GN=RBM34 PE=1 SV=2"	"0.000"	""	"12"	"3"	"4"	"3"	"430"	"48.5"	"10.11"	"304.12"	"12.44"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"23029"	"ENSG00000188739"	"RBM34"	"A8K8J7; hsa:23029; P42696; Q8N2Z8; Q9H5A1"	""	""	"0"	"0"	"91.4"	"79.2"	"120.2"	"116.4"	"97.1"	"102.6"	"156.3"	"161.0"	"205.8"	"389.0"	"437.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28288"	"ATP-binding cassette sub-family D member 3 OS=Homo sapiens OX=9606 GN=ABCD3 PE=1 SV=1"	"0.000"	""	"6"	"4"	"8"	"3"	"659"	"75.4"	"9.36"	"919.90"	"12.42"	"2"	"4"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf06472"	"5825"	"ENSG00000117528"	"ABCD3"	"D3DT46; hsa:5825; P28288; Q15271; Q6NUN5; Q96DA3; Q9H529"	"Nuclear receptors in lipid metabolism and toxicity; Fragile X syndrome"	"RHOA GTPase cycle; RHOC GTPase cycle; Class I peroxisomal membrane protein import; ABC transporters in lipid homeostasis"	"6"	"1"	"365.7"	"391.9"	"416.2"	"487.5"	"324.3"	"333.0"	"625.8"	"728.9"	"963.3"	"2488.6"	"3034.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36551"	"Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial OS=Homo sapiens OX=9606 GN=CPOX PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"454"	"50.1"	"8.25"	"765.36"	"12.41"	"1"	"2"	"other metabolic processes;other biological processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01218"	"1371"	"ENSG00000080819"	"CPOX"	"A8K275; B4DSD5; hsa:1371; P36551; Q14060; Q53F08; Q8IZ45; Q96AF3"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"24.4"	"19.1"	"32.1"	"62.5"	"23.5"	"20.9"	"38.4"	"51.2"	"75.4"	"488.0"	"1345.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95819"	"Mitogen-activated protein kinase kinase kinase kinase 4 OS=Homo sapiens OX=9606 GN=MAP4K4 PE=1 SV=2"	"0.000"	""	"5"	"5"	"8"	"3"	"1239"	"142.0"	"7.46"	"1266.08"	"12.39"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00780"	"9448"	"ENSG00000071054"	"MAP4K4"	"E7ESS2; hsa:9448; O75172; O95819; Q9NST7"	"MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"7"	"1"	"233.5"	"185.8"	"242.5"	"294.2"	"210.0"	"231.4"	"488.5"	"511.7"	"648.6"	"790.0"	"853.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75592"	"E3 ubiquitin-protein ligase MYCBP2 OS=Homo sapiens OX=9606 GN=MYCBP2 PE=1 SV=4"	"0.000"	""	"1"	"3"	"8"	"3"	"4678"	"513.3"	"7.02"	"1274.83"	"12.37"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00415, Pf03256, Pf08005, Pf08239, Pf13540, Pf13639"	"23077"	"ENSG00000005810"	"MYCBP2"	"A6NJC6; hsa:23077; O75592; Q5JSX8; Q5VZN6; Q6PIB6; Q9UQ11; Q9Y6E4"	"3q29 copy number variation syndrome"	""	"1"	"0"	"164.0"	"165.1"	"187.5"	"276.9"	"175.4"	"169.3"	"276.3"	"307.8"	"404.9"	"735.6"	"898.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2Q9"	"28S ribosomal protein S28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS28 PE=1 SV=1"	"0.000"	""	"27"	"3"	"5"	"3"	"187"	"20.8"	"9.10"	"771.82"	"12.34"	"2"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf10246"	"28957"	"ENSG00000147586"	"MRPS28"	"B2RDZ7; hsa:28957; Q96Q21; Q9Y2Q9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"109.0"	"72.0"	"136.4"	"145.2"	"95.4"	"109.1"	"172.1"	"176.2"	"237.9"	"461.1"	"759.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60941"	"Dystrobrevin beta OS=Homo sapiens OX=9606 GN=DTNB PE=1 SV=1"	"0.000"	""	"8"	"4"	"7"	"1"	"627"	"71.3"	"7.91"	"1204.63"	"12.34"	"3"	"4"	"cell-cell signaling;developmental processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00569, Pf09068, Pf09069"	"1838"	"ENSG00000138101"	"DTNB"	"B7Z733; F5GZG4; G5E9F6; hsa:1838; O43782; O60881; O60941; O75538; Q86VR4; Q96AW0; Q9UE14; Q9UE15; Q9UE16"	""	""	"0"	"0"	"0.0"	"3.3"	"4.1"	"5.9"	"3.8"	"0.0"	"8.8"	"8.4"	"16.2"	"47.3"	"48.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49840"	"Glycogen synthase kinase-3 alpha OS=Homo sapiens OX=9606 GN=GSK3A PE=1 SV=2"	"0.000"	""	"10"	"2"	"4"	"2"	"483"	"50.9"	"8.75"	"496.49"	"12.33"	"1"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"2931"	"ENSG00000105723"	"GSK3A"	"hsa:2931; O14959; P49840"	"IL-5 signaling pathway; Sterol regulatory element-binding proteins (SREBP) signaling; Leptin signaling pathway; B cell receptor signaling pathway; T cell receptor and co-stimulatory signaling; Wnt signaling pathway; Regulation of apoptosis by parathyroid hormone-related protein; Angiopoietin-like protein 8 regulatory pathway; Nonalcoholic fatty liver disease; Insulin signaling; Glycogen synthesis and degradation"	"Constitutive Signaling by AKT1 E17K in Cancer; XBP1(S) activates chaperone genes; AKT phosphorylates targets in the cytosol; Suppression of apoptosis; Maturation of nucleoprotein; Maturation of nucleoprotein"	"17"	"0"	"73.2"	"88.5"	"85.2"	"103.8"	"80.9"	"73.6"	"125.9"	"126.1"	"170.0"	"310.9"	"360.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11413"	"Glucose-6-phosphate 1-dehydrogenase OS=Homo sapiens OX=9606 GN=G6PD PE=1 SV=4"	"0.000"	""	"12"	"4"	"5"	"4"	"515"	"59.2"	"6.84"	"818.69"	"12.31"	"2"	"3"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00479, Pf02781"	"2539"	"ENSG00000160211"	"G6PD"	"D3DWX9; hsa:2539; P11413; Q16000; Q16765; Q8IU70; Q8IU88; Q8IUA6; Q96PQ2"	"Glutathione metabolism; Pentose phosphate metabolism; Cori cycle; Vitamin D receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; ATM signaling in development and disease ; Metabolic reprogramming in colon cancer; Vitamin D-sensitive calcium signaling in depression; Pentose phosphate pathway in senescent cells; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis in senescence; Sulfation biotransformation reaction"	"TP53 Regulates Metabolic Genes; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway"	"16"	"0"	"163.9"	"152.1"	"185.7"	"258.6"	"146.8"	"156.7"	"291.2"	"307.9"	"464.3"	"1260.6"	"2121.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6N069"	"N-alpha-acetyltransferase 16, NatA auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA16 PE=1 SV=2"	"0.000"	""	"5"	"4"	"9"	"2"	"864"	"101.4"	"7.87"	"1619.74"	"12.31"	"4"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity"	"Pf07719, Pf12569"	"79612"	"ENSG00000172766"	"NAA16"	"B0QZ59; hsa:79612; Q5VSP9; Q6N069; Q6P2D5; Q8N5J3; Q8N870"	""	""	"0"	"0"	"37.8"	"38.6"	"57.8"	"46.4"	"38.6"	"42.2"	"136.3"	"140.5"	"262.3"	"711.8"	"829.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H0W5"	"Coiled-coil domain-containing protein 8 OS=Homo sapiens OX=9606 GN=CCDC8 PE=1 SV=2"	""	""	"14"	"3"	"3"	"3"	"538"	"59.3"	"8.63"	""	"12.30"	""	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf14893"	"83987"	"ENSG00000169515"	"CCDC8"	"hsa:83987; Q8TB26; Q9H0W5"	""	"Neddylation"	"1"	"0"	"11.3"	"12.5"	"10.4"	"12.9"	"7.0"	"13.1"	"15.1"	"15.1"	"11.4"	"15.2"	"27.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZF1"	"Oxysterol-binding protein-related protein 8 OS=Homo sapiens OX=9606 GN=OSBPL8 PE=1 SV=3"	"0.000"	""	"5"	"3"	"6"	"3"	"889"	"101.1"	"6.96"	"1475.20"	"12.30"	"3"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114882"	"ENSG00000091039"	"OSBPL8"	"A8K1T2; E9PE66; E9PE68; hsa:114882; Q52LQ3; Q68D75; Q8WXP8; Q9BZF1; Q9P277"	""	"Acyl chain remodelling of PS"	"1"	"0"	"56.9"	"73.6"	"82.4"	"95.3"	"79.7"	"60.0"	"125.2"	"125.7"	"177.2"	"547.0"	"774.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95248"	"Myotubularin-related protein 5 OS=Homo sapiens OX=9606 GN=SBF1 PE=1 SV=4"	"0.000"	""	"3"	"3"	"5"	"3"	"1868"	"208.3"	"6.90"	"732.05"	"12.28"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"6305"	"ENSG00000100241"	"SBF1"	"A0A024R4Z9; A6PVG9; G5E933; hsa:6305; O60228; O95248; Q5JXD8; Q5PPM2; Q96GR9; Q9UGB8"	""	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the ER membrane"	"2"	"0"	"36.3"	"35.1"	"41.3"	"51.9"	"38.0"	"48.2"	"244.8"	"269.8"	"370.9"	"432.8"	"356.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13011"	"Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial OS=Homo sapiens OX=9606 GN=ECH1 PE=1 SV=2"	"0.000"	""	"19"	"4"	"6"	"4"	"328"	"35.8"	"8.00"	"1409.88"	"12.28"	"3"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00378"	"1891"	"ENSG00000104823; ENSG00000282853"	"ECH1"	"A8K745; hsa:1891; Q13011; Q8WVX0; Q96EZ9"	"Fatty acid biosynthesis; IL-18 signaling pathway"	"Peroxisomal protein import"	"3"	"0"	"25.2"	"27.5"	"48.3"	"43.5"	"28.3"	"31.9"	"59.5"	"56.9"	"99.0"	"257.3"	"409.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08378"	"Golgin subfamily A member 3 OS=Homo sapiens OX=9606 GN=GOLGA3 PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1498"	"167.3"	"5.44"	"1220.69"	"12.26"	"3"	"3"	""	"other membranes;cytosol;ER/Golgi;nucleus"	""	""	"2802"	"ENSG00000090615"	"GOLGA3"	"A5PKX6; hsa:2802; O43241; Q08378; Q6P9C7; Q86XW3; Q8TDA9; Q8WZA3"	""	"RND2 GTPase cycle"	"1"	"0"	"47.1"	"33.8"	"46.6"	"55.3"	"30.0"	"34.1"	"81.5"	"76.4"	"114.7"	"303.2"	"452.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75909"	"Cyclin-K OS=Homo sapiens OX=9606 GN=CCNK PE=1 SV=2"	"0.000"	""	"6"	"2"	"6"	"2"	"580"	"64.2"	"8.41"	"1248.26"	"12.26"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00134"	"8812"	"ENSG00000090061"	"CCNK"	"hsa:8812; O75909; Q59FT6; Q86U16; Q96B63; Q9NNY9"	"Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"10"	"0"	"36.0"	"38.3"	"39.1"	"43.3"	"34.0"	"36.7"	"58.4"	"77.3"	"105.6"	"312.3"	"460.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14573"	"Inositol 1,4,5-trisphosphate receptor type 3 OS=Homo sapiens OX=9606 GN=ITPR3 PE=1 SV=2"	"0.000"	""	"2"	"4"	"6"	"3"	"2671"	"303.9"	"6.48"	"1209.30"	"12.23"	"3"	"3"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3710"	"ENSG00000096433"	"ITPR3"	"hsa:3710; Q14573; Q14649; Q5TAQ2"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; MFAP5-mediated ovarian cancer cell motility and invasiveness; GPR40 pathway; Vitamin D-sensitive calcium signaling in depression; Airway smooth muscle cell contraction; Pleural mesothelioma; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells"	"Ion homeostasis; Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Sensory perception of sweet, bitter, and umami (glutamate) taste; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"25"	"0"	"61.4"	"54.0"	"78.9"	"102.3"	"63.4"	"68.7"	"133.9"	"135.9"	"199.7"	"635.2"	"1009.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43314"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2 OS=Homo sapiens OX=9606 GN=PPIP5K2 PE=1 SV=3"	"0.000"	""	"3"	"3"	"6"	"2"	"1243"	"140.3"	"8.22"	"1222.55"	"12.20"	"3"	"3"	"other metabolic processes;other biological processes"	"cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"23262"	"ENSG00000145725"	"PPIP5K2"	"A1NI53; A6NGS8; hsa:23262; O43314; Q8TB50"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"1"	"120.3"	"98.2"	"160.8"	"173.8"	"137.6"	"135.2"	"258.3"	"276.9"	"424.4"	"850.7"	"1066.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95425"	"Supervillin OS=Homo sapiens OX=9606 GN=SVIL PE=1 SV=2"	"0.000"	""	"2"	"3"	"6"	"3"	"2214"	"247.6"	"6.98"	"961.90"	"12.20"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626, Pf02209"	"6840"	"ENSG00000197321"	"SVIL"	"D3DRW9; hsa:6840; M1J557; O60611; O60612; O95425; Q5VZK5; Q5VZK6; Q9H1R7"	""	""	"0"	"0"	"110.5"	"90.5"	"123.5"	"140.2"	"108.7"	"115.9"	"179.8"	"179.6"	"273.8"	"573.9"	"710.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NY12"	"H/ACA ribonucleoprotein complex subunit 1 OS=Homo sapiens OX=9606 GN=GAR1 PE=1 SV=1"	"0.000"	""	"18"	"3"	"4"	"3"	"217"	"22.3"	"10.92"	"384.09"	"12.19"	"1"	"3"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf04410"	"54433"	"ENSG00000109534"	"GAR1"	"hsa:54433; Q5MJQ2; Q9NY12"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"163.7"	"156.0"	"197.1"	"238.9"	"159.2"	"160.3"	"274.7"	"283.1"	"382.4"	"990.4"	"1234.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXF1"	"Paraspeckle component 1 OS=Homo sapiens OX=9606 GN=PSPC1 PE=1 SV=1"	"0.000"	""	"10"	"4"	"7"	"3"	"523"	"58.7"	"6.67"	"891.80"	"12.19"	"3"	"4"	"stress response;other biological processes"	"nucleus;other cell component"	""	"Pf00076, Pf08075"	"55269"	"ENSG00000121390"	"PSPC1"	"hsa:55269; Q5JTQ3; Q8NCZ9; Q8WXE8; Q8WXF1; Q9NV36"	""	""	"0"	"0"	"424.3"	"424.2"	"478.8"	"503.8"	"402.5"	"414.9"	"565.8"	"557.8"	"635.9"	"1151.0"	"1631.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39023"	"60S ribosomal protein L3 OS=Homo sapiens OX=9606 GN=RPL3 PE=1 SV=2"	"0.000"	""	"15"	"7"	"11"	"7"	"403"	"46.1"	"10.18"	"2040.55"	"12.19"	"7"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00297"	"6122"	"ENSG00000100316"	"RPL3"	"B2RDV9; hsa:6122; P39023; Q15548; Q5I0G0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"580.8"	"523.6"	"663.4"	"812.8"	"546.9"	"556.5"	"932.1"	"969.8"	"1164.0"	"2759.0"	"4342.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBU8"	"Mortality factor 4-like protein 1 OS=Homo sapiens OX=9606 GN=MORF4L1 PE=1 SV=2"	"0.000"	""	"11"	"3"	"6"	"3"	"362"	"41.4"	"9.28"	"1119.88"	"12.17"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf05712, Pf11717"	"10933"	"ENSG00000185787"	"MORF4L1"	"B4DKN6; B7Z6R1; D3DW88; hsa:10933; O95899; Q5QTS1; Q6NVX8; Q86YT7; Q9HBP6; Q9NSW5; Q9UBU8"	"Pathways affected in adenoid cystic carcinoma"	"HATs acetylate histones"	"2"	"0"	"177.9"	"166.4"	"192.2"	"233.4"	"180.8"	"187.0"	"289.1"	"259.2"	"374.4"	"681.6"	"843.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2A7"	"Nck-associated protein 1 OS=Homo sapiens OX=9606 GN=NCKAP1 PE=1 SV=1"	"0.000"	""	"5"	"6"	"10"	"6"	"1128"	"128.7"	"6.62"	"2212.17"	"12.17"	"6"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf09735"	"10787"	"ENSG00000061676"	"NCKAP1"	"hsa:10787; O60329; Q53QN5; Q53S94; Q53Y35; Q9Y2A7"	"Exercise-induced circadian regulation; Regulation of actin cytoskeleton"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; VEGFA-VEGFR2 Pathway"	"9"	"0"	"400.5"	"327.1"	"458.0"	"480.7"	"391.4"	"400.7"	"748.2"	"782.5"	"1108.7"	"2010.8"	"2448.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92879"	"CUGBP Elav-like family member 1 OS=Homo sapiens OX=9606 GN=CELF1 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"486"	"52.0"	"8.46"	"1030.33"	"12.15"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"10658"	"ENSG00000149187"	"CELF1"	"B4E2U5; D3DQS0; F8W940; hsa:10658; Q4LE52; Q92879; Q9NP83; Q9NR06"	"Adipogenesis; mRNA processing"	""	"2"	"0"	"90.5"	"97.8"	"114.5"	"120.8"	"91.9"	"80.5"	"158.5"	"166.0"	"214.2"	"617.8"	"984.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43615"	"Mitochondrial import inner membrane translocase subunit TIM44 OS=Homo sapiens OX=9606 GN=TIMM44 PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"3"	"452"	"51.3"	"8.32"	"1410.68"	"12.15"	"3"	"3"	"cell organization and biogenesis;transport"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf04280"	"10469"	"ENSG00000104980"	"TIMM44"	"A8K0R9; D6W664; hsa:10469; O43615; Q8N193"	""	"Mitochondrial protein import"	"1"	"0"	"66.2"	"45.3"	"73.0"	"95.2"	"65.9"	"75.2"	"102.1"	"113.3"	"157.8"	"420.5"	"561.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13619"	"Cullin-4A OS=Homo sapiens OX=9606 GN=CUL4A PE=1 SV=3"	"0.000"	""	"5"	"4"	"7"	"1"	"759"	"87.6"	"8.13"	"1082.62"	"12.13"	"3"	"4"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8451"	"ENSG00000139842"	"CUL4A"	"A2A2W2; hsa:8451; O75834; Q13619; Q589T6; Q5TC62; Q6UP08; Q9UP17"	"Hippo-Merlin signaling dysregulation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Neddylation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; DNA Damage Recognition in GG-NER; Dual Incision in GG-NER"	"13"	"0"	"82.1"	"87.7"	"80.7"	"97.7"	"64.6"	"70.6"	"152.8"	"145.8"	"239.3"	"688.4"	"913.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0G5"	"Nuclear speckle splicing regulatory protein 1 OS=Homo sapiens OX=9606 GN=NSRP1 PE=1 SV=1"	"0.000"	""	"8"	"4"	"8"	"4"	"558"	"66.4"	"8.84"	"1259.00"	"12.13"	"4"	"4"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09745, Pf20427"	"84081"	"ENSG00000126653"	"NSRP1"	"hsa:84081; Q6FI71; Q9H0G5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"240.7"	"211.9"	"254.1"	"304.5"	"220.6"	"233.7"	"328.2"	"353.3"	"423.3"	"892.6"	"1095.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6A4"	"Cilia- and flagella-associated protein 20 OS=Homo sapiens OX=9606 GN=CFAP20 PE=1 SV=1"	"0.000"	""	"18"	"3"	"6"	"3"	"193"	"22.8"	"9.76"	"1203.85"	"12.13"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf05018"	"29105"	"ENSG00000070761"	"CFAP20"	"hsa:29105; Q9Y6A4"	""	""	"0"	"0"	"106.2"	"86.7"	"103.2"	"134.8"	"90.4"	"91.7"	"151.1"	"171.7"	"204.8"	"467.2"	"645.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13601"	"KRR1 small subunit processome component homolog OS=Homo sapiens OX=9606 GN=KRR1 PE=1 SV=4"	"0.000"	""	"11"	"5"	"9"	"5"	"381"	"43.6"	"9.77"	"1957.05"	"12.10"	"5"	"4"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf17903"	"11103"	"ENSG00000111615"	"KRR1"	"A0FIK6; A0JLP0; B2R989; E7EUQ0; hsa:11103; Q13601; Q8NEA8; Q8TC37; Q96AT5"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"512.2"	"454.2"	"562.1"	"557.8"	"466.0"	"509.0"	"791.2"	"799.8"	"1051.2"	"1796.6"	"2138.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EK6"	"Glucosamine 6-phosphate N-acetyltransferase OS=Homo sapiens OX=9606 GN=GNPNAT1 PE=1 SV=1"	"0.000"	""	"22"	"3"	"7"	"3"	"184"	"20.7"	"7.99"	"1850.62"	"12.09"	"3"	"3"	"other metabolic processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00583"	"64841"	"ENSG00000100522"	"GNPNAT1"	"hsa:64841; Q96EK6"	""	"Synthesis of UDP-N-acetyl-glucosamine"	"1"	"0"	"160.8"	"147.9"	"152.7"	"181.5"	"139.4"	"146.4"	"185.9"	"205.3"	"246.2"	"544.5"	"993.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15031"	"Probable leucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=LARS2 PE=1 SV=2"	"0.000"	""	"6"	"4"	"6"	"4"	"903"	"101.9"	"8.22"	"772.74"	"12.09"	"2"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00133, Pf08264"	"23395"	"ENSG00000011376"	"LARS2"	"hsa:23395; Q15031"	"Amino acid metabolism; IL-18 signaling pathway; Primary ovarian insufficiency"	"Mitochondrial tRNA aminoacylation"	"4"	"0"	"207.7"	"194.1"	"218.2"	"237.0"	"190.1"	"240.9"	"500.3"	"522.1"	"722.6"	"1422.0"	"1771.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFD5"	"AT-rich interactive domain-containing protein 1B OS=Homo sapiens OX=9606 GN=ARID1B PE=1 SV=2"	"0.000"	""	"1"	"2"	"6"	"2"	"2236"	"236.0"	"6.73"	"1122.45"	"12.06"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"167.6"	"128.5"	"172.6"	"215.3"	"165.4"	"164.2"	"302.1"	"343.8"	"557.3"	"1226.5"	"1465.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHR4"	"Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 OS=Homo sapiens OX=9606 GN=BAIAP2L1 PE=1 SV=2"	"0.000"	""	"10"	"3"	"5"	"3"	"511"	"56.8"	"8.68"	"980.46"	"12.03"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;other molecular function"	"Pf08397, Pf14604"	"55971"	"ENSG00000006453"	"BAIAP2L1"	"A4D268; hsa:55971; Q75L21; Q75L22; Q96CV4; Q9H5F5; Q9UHR4; Q9Y2M8"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOF GTPase cycle"	"4"	"0"	"247.9"	"145.5"	"313.4"	"326.3"	"252.0"	"277.2"	"349.5"	"317.7"	"343.8"	"383.4"	"457.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC35"	"Echinoderm microtubule-associated protein-like 4 OS=Homo sapiens OX=9606 GN=EML4 PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"981"	"108.8"	"6.40"	"645.51"	"12.02"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451, Pf07714"	"27436"	"ENSG00000143924"	"EML4"	"A6H8Y6; A6P4T4; A6P4V4; B2RBK3; B2RTW7; B5MCW9; hsa:27436; Q3SWW0; Q53R29; Q53TW8; Q6PJ45; Q9HC35; Q9NV40"	"Non-small cell lung cancer"	"EML4 and NUDC in mitotic spindle formation; ALK mutants bind TKIs; Nuclear events stimulated by ALK signaling in cancer"	"5"	"0"	"138.4"	"137.9"	"149.5"	"162.5"	"121.4"	"132.1"	"229.8"	"262.4"	"354.3"	"1400.8"	"1872.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WW12"	"PEST proteolytic signal-containing nuclear protein OS=Homo sapiens OX=9606 GN=PCNP PE=1 SV=2"	"0.000"	""	"20"	"3"	"6"	"3"	"178"	"18.9"	"7.49"	"1156.84"	"12.02"	"3"	"3"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"nucleus"	""	"Pf15473"	"57092"	"ENSG00000081154"	"PCNP"	"B2RBE7; D3DN52; hsa:57092; Q53GF3; Q6AI44; Q8WW12; Q96CU3; Q9NS81"	""	""	"0"	"0"	"202.9"	"177.3"	"246.5"	"306.6"	"194.0"	"176.4"	"266.2"	"279.6"	"319.1"	"1207.6"	"2141.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13425"	"Beta-2-syntrophin OS=Homo sapiens OX=9606 GN=SNTB2 PE=1 SV=1"	"0.000"	""	"6"	"3"	"9"	"3"	"540"	"57.9"	"8.82"	"2198.73"	"12.00"	"3"	"3"	""	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00595, Pf18012"	"6645"	"ENSG00000168807"	"SNTB2"	"hsa:6645; Q13425; Q9BY09"	""	""	"0"	"0"	"168.9"	"158.1"	"219.2"	"254.6"	"176.0"	"170.2"	"297.8"	"299.5"	"409.4"	"873.7"	"1061.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y678"	"Coatomer subunit gamma-1 OS=Homo sapiens OX=9606 GN=COPG1 PE=1 SV=1"	"0.000"	""	"4"	"3"	"6"	"2"	"874"	"97.7"	"5.47"	"1329.61"	"11.99"	"3"	"3"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf01602, Pf08752, Pf16381"	"22820"	"ENSG00000181789"	"COPG1"	"A8K6M8; B3KMF6; hsa:22820; Q54AC4; Q9Y678"	"VEGFA-VEGFR2 signaling"	"COPI-mediated anterograde transport; COPI-dependent Golgi-to-ER retrograde traffic"	"3"	"1"	"243.3"	"248.3"	"232.2"	"254.0"	"206.6"	"234.9"	"298.5"	"290.0"	"352.3"	"610.4"	"855.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05397"	"Focal adhesion kinase 1 OS=Homo sapiens OX=9606 GN=PTK2 PE=1 SV=2"	"0.000"	""	"4"	"4"	"7"	"4"	"1052"	"119.2"	"6.62"	"1539.28"	"11.99"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;kinase activity;other molecular function"	"Pf00373, Pf03623, Pf07714, Pf18038"	"5747"	"ENSG00000169398"	"PTK2"	"B4E2N6; F5H4S4; hsa:5747; J3QT16; Q05397; Q14291; Q8IYN9; Q9UD85"	"Androgen receptor signaling pathway; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; Corticotropin-releasing hormone signaling pathway; Alpha 6 beta 4 signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); Apoptosis-related network due to altered Notch3 in ovarian cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Overview of nanoparticle effects; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Prion disease pathway; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Hippo-Merlin signaling dysregulation; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Small cell lung cancer; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; Pleural mesothelioma; Regulation of actin cytoskeleton; 2q13 copy number variation syndrome; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Signal regulatory protein family interactions; EPHB-mediated forward signaling; DCC mediated attractive signaling; RAF/MAP kinase cascade; VEGFA-VEGFR2 Pathway; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; NCAM signaling for neurite out-growth; MET activates PTK2 signaling; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Apoptotic cleavage of cellular proteins"	"48"	"0"	"164.8"	"128.9"	"204.1"	"215.8"	"169.2"	"228.5"	"740.1"	"794.1"	"1063.2"	"1617.0"	"1456.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GQ7"	"Probable ATP-dependent RNA helicase DDX27 OS=Homo sapiens OX=9606 GN=DDX27 PE=1 SV=2"	"0.000"	""	"6"	"4"	"6"	"4"	"796"	"89.8"	"9.28"	"817.65"	"11.98"	"2"	"4"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271"	"55661"	""	"DDX27"	"A0AVB6; B7ZLY1; hsa:55661; Q5VXM7; Q8WYG4; Q969N7; Q96F57; Q96GQ7; Q96L97; Q9BWY9; Q9BXF0; Q9H990; Q9NWU3; Q9P0C2; Q9UGD6"	""	""	"0"	"0"	"88.9"	"87.0"	"87.2"	"103.6"	"91.3"	"82.9"	"118.2"	"131.5"	"149.6"	"332.8"	"357.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5RKV6"	"Exosome complex component MTR3 OS=Homo sapiens OX=9606 GN=EXOSC6 PE=1 SV=1"	"0.000"	""	"18"	"3"	"5"	"3"	"272"	"28.2"	"6.28"	"838.93"	"11.97"	"2"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf01138"	"118460"	"ENSG00000223496"	"EXOSC6"	"hsa:118460; Q5RKV6"	""	"ATF4 activates genes in response to endoplasmic reticulum  stress; Major pathway of rRNA processing in the nucleolus and cytosol; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"142.0"	"125.1"	"149.1"	"198.9"	"143.7"	"137.0"	"196.0"	"193.2"	"252.8"	"633.7"	"1012.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTT0"	"Acidic leucine-rich nuclear phosphoprotein 32 family member E OS=Homo sapiens OX=9606 GN=ANP32E PE=1 SV=1"	"0.000"	""	"11"	"2"	"6"	"2"	"268"	"30.7"	"3.85"	"1339.75"	"11.95"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14580"	"81611"	"ENSG00000143401"	"ANP32E"	"B4E0I6; E9PEA6; hsa:81611; Q5TB18; Q5TB20; Q8N1S4; Q8WWW9; Q9BTT0"	""	""	"0"	"0"	"117.6"	"82.9"	"139.0"	"184.1"	"118.3"	"96.5"	"196.6"	"204.8"	"272.3"	"566.4"	"767.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49711"	"Transcriptional repressor CTCF OS=Homo sapiens OX=9606 GN=CTCF PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"727"	"82.7"	"6.96"	"819.90"	"11.95"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf13909"	"10664"	"ENSG00000102974"	"CTCF"	"B5MC38; hsa:10664; P49711; Q53XI7; Q59EL8"	"MECP2 and associated Rett syndrome; Prion disease pathway; Model for regulation of MSMP expression in cancer cells and its proangiogenic role in ovarian tumors; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis"	"5"	"0"	"126.7"	"116.3"	"156.5"	"188.5"	"146.8"	"136.3"	"231.7"	"239.1"	"286.9"	"582.7"	"858.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWS0"	"PIH1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PIH1D1 PE=1 SV=1"	"0.000"	""	"19"	"4"	"6"	"4"	"290"	"32.3"	"5.14"	"1071.69"	"11.94"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08190, Pf18201"	"55011"	"ENSG00000104872"	"PIH1D1"	"B4DGN7; B4E2X7; hsa:55011; Q9BVL0; Q9NWS0"	""	""	"0"	"0"	"79.3"	"58.5"	"89.3"	"99.8"	"80.4"	"78.6"	"203.2"	"207.3"	"369.2"	"959.6"	"1068.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UV5"	"Ubiquitin carboxyl-terminal hydrolase 48 OS=Homo sapiens OX=9606 GN=USP48 PE=1 SV=1"	"0.000"	""	"5"	"4"	"7"	"4"	"1035"	"119.0"	"6.05"	"1979.43"	"11.94"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00443"	"84196"	"ENSG00000090686"	"USP48"	"B7ZKS7; hsa:84196; Q2M3I4; Q5SZI4; Q5T3T5; Q6NX53; Q86UV5; Q8N3F6; Q96F64; Q96IQ3; Q9H5N3; Q9H5T7; Q9NUJ6; Q9NXR0"	""	"Ub-specific processing proteases"	"1"	"0"	"26.5"	"27.7"	"34.1"	"40.9"	"27.5"	"30.2"	"98.4"	"105.0"	"233.1"	"719.7"	"805.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UVY6"	"DBH-like monooxygenase protein 1 OS=Homo sapiens OX=9606 GN=MOXD1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"3"	"613"	"69.6"	"6.43"	"1180.11"	"11.93"	"3"	"3"	"other metabolic processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf01082, Pf03351, Pf03712"	"26002"	"ENSG00000079931"	"MOXD1"	"hsa:26002; Q5THU6; Q6UVY6; Q8NC97; Q8WV49; Q9H4M6; Q9Y4U3"	""	""	"0"	"0"	"12.8"	"18.7"	"11.8"	"13.6"	"9.9"	"12.4"	"33.4"	"31.9"	"49.3"	"148.4"	"242.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36542"	"ATP synthase subunit gamma, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1C PE=1 SV=1"	"0.000"	""	"16"	"5"	"10"	"5"	"298"	"33.0"	"9.22"	"1546.48"	"11.93"	"5"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf00231"	"509"	"ENSG00000165629"	"ATP5F1C"	"A8KA31; hsa:509; P36542; Q5VYP3; Q6I9V2; Q96AS8"	"Electron transport chain: OXPHOS system in mitochondria"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"3"	"0"	"163.3"	"136.3"	"154.7"	"233.5"	"138.1"	"159.3"	"323.6"	"327.6"	"486.1"	"1894.1"	"3013.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14562"	"Ubiquitin domain-containing protein UBFD1 OS=Homo sapiens OX=9606 GN=UBFD1 PE=1 SV=2"	"0.000"	""	"11"	"3"	"5"	"3"	"309"	"33.4"	"5.77"	"699.52"	"11.89"	"2"	"3"	""	""	""	"Pf00240"	"56061"	"ENSG00000103353"	"UBFD1"	"A8MW58; D3DWF2; hsa:56061; O14562"	""	""	"0"	"0"	"80.7"	"53.5"	"80.9"	"116.6"	"81.4"	"77.4"	"181.9"	"203.7"	"343.3"	"1433.7"	"1995.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4L1"	"Hypoxia up-regulated protein 1 OS=Homo sapiens OX=9606 GN=HYOU1 PE=1 SV=1"	"0.000"	""	"4"	"3"	"4"	"3"	"999"	"111.3"	"5.22"	"296.50"	"11.86"	"1"	"3"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"other molecular function"	"Pf00012"	"10525"	"ENSG00000149428; ENSG00000280682"	"HYOU1"	"A8C1Z0; B7Z909; hsa:10525; Q2I204; Q53H25; Q9Y4L1"	"VEGFA-VEGFR2 signaling"	"XBP1(S) activates chaperone genes; Scavenging by Class F Receptors"	"3"	"0"	"114.1"	"75.2"	"119.4"	"160.6"	"99.4"	"99.6"	"192.6"	"171.8"	"226.5"	"1241.4"	"2407.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5N7"	"39S ribosomal protein L50, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL50 PE=1 SV=2"	"0.000"	""	"21"	"2"	"4"	"2"	"158"	"18.3"	"7.88"	"894.17"	"11.80"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	""	"Pf10501"	"54534"	"ENSG00000136897"	"MRPL50"	"B7Z358; hsa:54534; Q5T7E0; Q8N5N7; Q9NX15"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"101.6"	"91.2"	"119.3"	"130.2"	"93.9"	"90.0"	"157.0"	"185.4"	"222.4"	"460.0"	"701.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYK5"	"39S ribosomal protein L39, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL39 PE=1 SV=3"	"0.000"	""	"10"	"3"	"4"	"3"	"338"	"38.7"	"7.65"	"407.44"	"11.78"	"1"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	""	"54148"	"ENSG00000154719"	"MRPL39"	"C9JYA5; hsa:54148; Q32Q74; Q5QTR3; Q96Q65; Q9BSQ7; Q9BZV6; Q9NX44; Q9NYK5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"82.2"	"64.5"	"78.5"	"124.6"	"82.6"	"91.5"	"190.9"	"237.3"	"332.4"	"1118.6"	"1871.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16881"	"Thioredoxin reductase 1, cytoplasmic OS=Homo sapiens OX=9606 GN=TXNRD1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"649"	"70.9"	"7.39"	"348.17"	"11.76"	"1"	"2"	"cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462, Pf02852, Pf07992"	"7296"	"ENSG00000198431"	"TXNRD1"	"B7Z1F4; B7Z3Y8; B7Z904; E9PMY9; F5H780; hsa:7296; Q16881; Q6FI31; Q6VB40; Q6VB41; Q6VB42; Q6VBP2; Q6VBP3; Q6VBP4; Q6VBP5; Q6VBP9; Q6VBQ0; Q6YNQ1; Q76P53; Q7LA96; Q8WVC8; Q99475; Q9UES8; Q9UH79"	"Selenium micronutrient network; Selenium micronutrient network ; Selenium micronutrient network; Nuclear receptors meta-pathway; NRF2 pathway; Oxidative stress response; Ferroptosis"	"Interconversion of nucleotide di- and triphosphates; PPARA activates gene expression; TP53 Regulates Metabolic Genes; Detoxification of Reactive Oxygen Species; NFE2L2 regulating anti-oxidant/detoxification enzymes; Metabolism of ingested H2SeO4 and H2SeO3 into H2Se; Uptake and function of diphtheria toxin; Metabolism of ingested MeSeO2H into MeSeH"	"15"	"0"	"17.8"	"17.2"	"20.6"	"22.1"	"19.8"	"16.2"	"40.3"	"46.8"	"80.4"	"359.0"	"506.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18621"	"60S ribosomal protein L17 OS=Homo sapiens OX=9606 GN=RPL17 PE=1 SV=3"	"0.000"	""	"15"	"4"	"8"	"4"	"184"	"21.4"	"10.17"	"1414.55"	"11.76"	"4"	"4"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00237"	"6139"	"ENSG00000265681"	"RPL17"	"B2R4H3; B4E3C2; B5ME31; hsa:6139; J3QL51; P18621; Q3KQW2; Q6NZ54; Q7M4M5"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Formation of a pool of free 40S subunits; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"396.8"	"429.6"	"557.6"	"680.7"	"448.3"	"410.4"	"730.8"	"773.4"	"886.0"	"1625.9"	"2464.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95235"	"Kinesin-like protein KIF20A OS=Homo sapiens OX=9606 GN=KIF20A PE=1 SV=1"	"0.000"	""	"6"	"4"	"7"	"4"	"890"	"100.2"	"6.92"	"1453.72"	"11.75"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"10112"	"ENSG00000112984"	"KIF20A"	"B4DL79; D3DQB6; hsa:10112; O95235"	""	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; Mitotic Telophase/Cytokinesis"	"4"	"0"	"143.8"	"122.9"	"149.1"	"189.6"	"144.0"	"136.2"	"219.2"	"228.7"	"293.1"	"562.5"	"756.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P68400"	"Casein kinase II subunit alpha OS=Homo sapiens OX=9606 GN=CSNK2A1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"391"	"45.1"	"7.74"	"1112.35"	"11.74"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1457"	"ENSG00000101266"	"CSNK2A1"	"B4DYS6; D3DVV8; hsa:1457; P19138; P20426; P68400; Q14013; Q5U065"	"Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Translation inhibitors in chronically activated PDGFRA cells; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; Regulation of TP53 Activity through Phosphorylation; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"21"	"0"	"117.7"	"119.1"	"144.3"	"189.4"	"120.4"	"122.2"	"220.4"	"205.6"	"291.8"	"859.7"	"1281.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53618"	"Coatomer subunit beta OS=Homo sapiens OX=9606 GN=COPB1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"4"	"1"	"953"	"107.1"	"6.05"	"1132.66"	"11.73"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01602, Pf07718, Pf14806"	"1315"	"ENSG00000129083"	"COPB1"	"D3DQX0; hsa:1315; P53618; Q6GTT7; Q9NTK2; Q9UNW7"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Neutrophil degranulation; COPI-mediated anterograde transport"	"3"	"0"	"62.5"	"55.0"	"67.1"	"78.3"	"63.3"	"67.4"	"78.8"	"86.2"	"115.8"	"220.7"	"314.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46109"	"Crk-like protein OS=Homo sapiens OX=9606 GN=CRKL PE=1 SV=1"	"0.000"	""	"13"	"3"	"6"	"3"	"303"	"33.8"	"6.74"	"1236.98"	"11.71"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf07653"	"1399"	"ENSG00000099942"	"CRKL"	"A8KA44; D3DX35; hsa:1399; P46109"	"Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; Chemokine signaling pathway; EGF/EGFR signaling pathway; 22q11.2 copy number variation syndrome; IL-2 signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"Downstream signal transduction; Regulation of signaling by CBL; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1; MET receptor recycling"	"21"	"0"	"263.5"	"210.9"	"280.0"	"303.2"	"215.1"	"218.7"	"293.2"	"304.9"	"279.3"	"381.0"	"523.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAU5"	"Regulator of nonsense transcripts 2 OS=Homo sapiens OX=9606 GN=UPF2 PE=1 SV=1"	"0.000"	""	"3"	"3"	"7"	"3"	"1272"	"147.7"	"5.69"	"1549.61"	"11.71"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf04050"	"26019"	"ENSG00000151461"	"UPF2"	"A6NLJ5; D3DRS0; hsa:26019; Q14BM1; Q5W0J4; Q8N8U1; Q9H1J2; Q9HAU5; Q9NWL1; Q9P2D9; Q9Y4M9"	""	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"2"	"0"	"199.4"	"196.9"	"236.0"	"230.5"	"189.9"	"189.7"	"284.8"	"282.1"	"337.6"	"580.2"	"671.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P58107"	"Epiplakin OS=Homo sapiens OX=9606 GN=EPPK1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"1"	"5088"	"555.3"	"5.62"	"558.96"	"11.71"	"1"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00681"	"83481"	"ENSG00000261150"	"EPPK1"	"A0A087X1U6; hsa:83481; P58107; Q76E58; Q9NSU9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2T1"	"GMP reductase 2 OS=Homo sapiens OX=9606 GN=GMPR2 PE=1 SV=1"	"0.000"	""	"11"	"3"	"4"	"2"	"348"	"37.9"	"7.23"	"353.06"	"11.71"	"1"	"3"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"51292"	"ENSG00000100938; ENSG00000284752"	"GMPR2"	"D3DS66; hsa:51292; Q567T0; Q6IAJ8; Q86T14; Q9P2T1"	""	"Purine salvage"	"1"	"1"	"68.2"	"66.0"	"84.8"	"95.7"	"82.8"	"88.3"	"285.9"	"352.7"	"606.1"	"1851.8"	"2831.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62487"	"DNA-directed RNA polymerase II subunit RPB7 OS=Homo sapiens OX=9606 GN=POLR2G PE=1 SV=1"	"0.000"	""	"31"	"3"	"4"	"3"	"172"	"19.3"	"5.54"	"308.58"	"11.65"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00575, Pf03876"	"5436"	"ENSG00000168002"	"POLR2G"	"B2R5C0; hsa:5436; P52433; P62487; Q2M1Z4"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"65.8"	"61.2"	"74.6"	"96.3"	"67.2"	"65.0"	"109.7"	"121.2"	"150.2"	"273.0"	"323.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07737"	"Profilin-1 OS=Homo sapiens OX=9606 GN=PFN1 PE=1 SV=2"	"0.000"	""	"19"	"2"	"6"	"2"	"140"	"15.0"	"8.27"	"1315.67"	"11.63"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00235"	"5216"	"ENSG00000108518"	"PFN1"	"hsa:5216; P07737; Q53Y44"	"Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Burn wound healing; Regulation of actin cytoskeleton; G13 signaling pathway"	"RHO GTPases Activate Formins; Platelet degranulation ; PCP/CE pathway; Signaling by ROBO receptors"	"9"	"0"	"99.9"	"80.7"	"205.0"	"388.5"	"99.8"	"77.6"	"161.3"	"188.0"	"195.5"	"399.7"	"510.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30050"	"60S ribosomal protein L12 OS=Homo sapiens OX=9606 GN=RPL12 PE=1 SV=1"	"0.000"	""	"24"	"4"	"9"	"4"	"165"	"17.8"	"9.42"	"1745.06"	"11.62"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00298, Pf03946"	"6136"	"ENSG00000197958"	"RPL12"	"hsa:6136; P30050; Q5VVV2; Q6PB27"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"477.2"	"465.8"	"644.5"	"843.4"	"508.9"	"447.5"	"868.8"	"909.7"	"1084.5"	"2160.0"	"2898.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46782"	"40S ribosomal protein S5 OS=Homo sapiens OX=9606 GN=RPS5 PE=1 SV=4"	"0.000"	""	"24"	"3"	"6"	"3"	"204"	"22.9"	"9.72"	"1118.14"	"11.61"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"6193"	"ENSG00000083845"	"RPS5"	"B2R4T2; hsa:6193; P46782; Q96BN0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"59.5"	"54.5"	"62.7"	"94.0"	"60.4"	"55.9"	"103.2"	"99.4"	"122.0"	"260.5"	"294.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05204"	"Non-histone chromosomal protein HMG-17 OS=Homo sapiens OX=9606 GN=HMGN2 PE=1 SV=3"	"0.000"	""	"29"	"3"	"7"	"3"	"90"	"9.4"	"9.99"	"1670.22"	"11.60"	"3"	"2"	"cell organization and biogenesis;stress response;other biological processes"	"non-structural extracellular;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3151"	"ENSG00000198830"	"HMGN2"	"hsa:3151; P05204; Q0VGD5; Q6FGI5; Q96C64"	""	""	"0"	"0"	"369.4"	"323.5"	"261.6"	"480.8"	"288.8"	"274.6"	"342.6"	"354.3"	"360.2"	"252.4"	"189.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N8S7"	"Protein enabled homolog OS=Homo sapiens OX=9606 GN=ENAH PE=1 SV=2"	"0.000"	""	"7"	"3"	"7"	"3"	"591"	"66.5"	"6.93"	"1927.71"	"11.58"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"55740"	"ENSG00000154380"	"ENAH"	"D0PQI2; hsa:55740; Q502W5; Q5T5M7; Q5VTQ9; Q5VTR0; Q8N8S7; Q9NVF3; Q9UFB8"	"Regulation of actin cytoskeleton"	"Generation of second messenger molecules; Signaling by ROBO receptors"	"3"	"0"	"333.6"	"268.6"	"316.7"	"346.2"	"274.9"	"309.8"	"383.9"	"370.9"	"424.7"	"720.5"	"1064.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16352"	"Alpha-internexin OS=Homo sapiens OX=9606 GN=INA PE=1 SV=2"	"0.000"	""	"8"	"4"	"8"	"3"	"499"	"55.4"	"5.40"	"1376.95"	"11.58"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00038, Pf04732"	"9118"	"ENSG00000148798"	"INA"	"B1AQK0; hsa:9118; Q16352; Q9BRC5"	""	""	"0"	"0"	"193.2"	"148.9"	"225.7"	"332.7"	"167.2"	"161.3"	"315.8"	"326.4"	"441.9"	"1004.5"	"1277.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02818"	"Nucleobindin-1 OS=Homo sapiens OX=9606 GN=NUCB1 PE=1 SV=4"	"0.000"	""	"8"	"3"	"6"	"3"	"461"	"53.8"	"5.25"	"1304.61"	"11.54"	"3"	"3"	"signal transduction"	"ER/Golgi"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13499"	"4924"	"ENSG00000104805"	"NUCB1"	"B2RD64; hsa:4924; Q02818; Q15838; Q7Z4J7; Q9BUR1"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"2"	"0"	"306.7"	"264.2"	"344.1"	"376.5"	"285.3"	"292.5"	"364.6"	"397.0"	"458.0"	"731.3"	"916.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2T7"	"Y-box-binding protein 2 OS=Homo sapiens OX=9606 GN=YBX2 PE=1 SV=2"	"0.000"	""	"16"	"3"	"5"	"1"	"364"	"38.5"	"10.80"	"729.94"	"11.53"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00313"	"51087"	"ENSG00000006047; ENSG00000288504"	"YBX2"	"D3DTP1; hsa:51087; Q8N4P0; Q9Y2T7"	"Male infertility"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60174"	"Triosephosphate isomerase OS=Homo sapiens OX=9606 GN=TPI1 PE=1 SV=3"	"0.000"	""	"14"	"3"	"6"	"3"	"286"	"30.8"	"5.92"	"1283.97"	"11.52"	"3"	"3"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00121"	""	"ENSPPYG00000004207; ENSPTRG00000004595"	"TPI1"	"A0A2J8JEI5; A0A2J8JEJ3; A0A2J8TBG7; A0A6D2X563; H2NGA4"	""	""	"0"	"0"	"128.8"	"124.4"	"234.3"	"433.9"	"122.8"	"115.3"	"249.6"	"266.4"	"309.9"	"720.2"	"874.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15504"	"Nucleoporin NUP42 OS=Homo sapiens OX=9606 GN=NUP42 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"423"	"44.8"	"9.19"	"518.35"	"11.51"	"1"	"2"	"transport"	"other membranes;cytosol;nucleus"	"other molecular function"	""	"11097"	"ENSG00000136243"	"NUP42"	"A4D143; B4DP42; hsa:11097; O15504; Q49AE7; Q9BS49"	""	"HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"81.8"	"57.3"	"76.4"	"101.6"	"76.8"	"82.7"	"104.4"	"110.1"	"138.9"	"241.4"	"358.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14923"	"Junction plakoglobin OS=Homo sapiens OX=9606 GN=JUP PE=1 SV=3"	"0.000"	""	"5"	"4"	"6"	"3"	"745"	"81.7"	"6.14"	"1200.27"	"11.51"	"3"	"3"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"3728"	"ENSG00000173801"	"JUP"	"hsa:3728; P14923; Q15093; Q15151; Q7L3S5; Q86W21; Q9BWC4; Q9HCX9"	"Arrhythmogenic right ventricular cardiomyopathy; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Ectoderm differentiation; Epithelial to mesenchymal transition in colorectal cancer; Opioid receptor pathways"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle; Neutrophil degranulation; Formation of the cornified envelope; RHOQ GTPase cycle; RHOJ GTPase cycle; VEGFR2 mediated vascular permeability; Adherens junctions interactions; Regulation of CDH11 function; Regulation of CDH19 Expression and Function; CDH11 homotypic and heterotypic interactions; RHOH GTPase cycle"	"21"	"0"	"141.7"	"156.8"	"269.1"	"210.0"	"112.6"	"137.5"	"234.5"	"249.8"	"305.4"	"678.6"	"1059.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01968"	"Inositol polyphosphate 5-phosphatase OCRL OS=Homo sapiens OX=9606 GN=OCRL PE=1 SV=3"	"0.000"	""	"5"	"4"	"7"	"4"	"901"	"104.1"	"6.55"	"1563.51"	"11.49"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00620, Pf03372, Pf16726"	"4952"	"ENSG00000122126"	"OCRL"	"A6NKI1; A8KAP2; B7ZLX2; hsa:4952; O60800; Q01968; Q15684; Q15774; Q4VY09; Q4VY10; Q5JQF1; Q5JQF2; Q9UJG5; Q9UMA5"	"VEGFA-VEGFR2 signaling; Ciliopathies; Bardet-Biedl syndrome"	"Clathrin-mediated endocytosis; RAC3 GTPase cycle; RHOJ GTPase cycle; Golgi Associated Vesicle Biogenesis; Synthesis of PIPs at the plasma membrane; Synthesis of PIPs at the Golgi membrane; Synthesis of IP2, IP, and Ins in the cytosol; Synthesis of IP3 and IP4 in the cytosol"	"11"	"0"	"124.6"	"96.0"	"135.9"	"159.9"	"122.3"	"145.0"	"301.3"	"313.5"	"442.9"	"1004.9"	"1221.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20674"	"Cytochrome c oxidase subunit 5A, mitochondrial OS=Homo sapiens OX=9606 GN=COX5A PE=1 SV=2"	"0.000"	""	"27"	"3"	"6"	"3"	"150"	"16.8"	"6.79"	"1053.38"	"11.48"	"3"	"3"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02284"	"9377"	"ENSG00000178741"	"COX5A"	"hsa:9377; P20674; P30045; Q8TB65"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation; Arachidonate epoxygenase / epoxide hydrolase"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"8"	"0"	"88.1"	"78.8"	"122.2"	"148.4"	"93.0"	"90.9"	"173.4"	"207.1"	"309.3"	"1099.7"	"1734.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82664"	"28S ribosomal protein S10, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS10 PE=1 SV=2"	"0.000"	""	"16"	"2"	"4"	"2"	"201"	"23.0"	"8.00"	"1187.70"	"11.48"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"55173"	"ENSG00000048544"	"MRPS10"	"B2RE89; hsa:55173; P82664; Q9H3E5; Q9NVR3"	""	"Mitochondrial translation elongation; Mitochondrial translation initiation; Mitochondrial translation termination"	"3"	"0"	"37.9"	"35.6"	"48.3"	"93.3"	"39.2"	"46.8"	"88.2"	"101.1"	"141.5"	"366.2"	"452.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDN6"	"Ribosome biogenesis protein BRX1 homolog OS=Homo sapiens OX=9606 GN=BRIX1 PE=1 SV=2"	"0.000"	""	"10"	"3"	"7"	"3"	"353"	"41.4"	"9.92"	"1351.51"	"11.45"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"55299"	"ENSG00000113460"	"BRIX1"	"A8K0P5; hsa:55299; Q3ZTT4; Q8N453; Q8TDN6; Q96DH1"	"Gastric cancer network 2"	""	"1"	"0"	"103.9"	"99.0"	"159.2"	"191.6"	"128.2"	"105.0"	"237.8"	"251.2"	"349.2"	"893.6"	"1322.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBD5"	"Origin recognition complex subunit 3 OS=Homo sapiens OX=9606 GN=ORC3 PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"3"	"711"	"82.2"	"7.61"	"968.23"	"11.44"	"3"	"3"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf07034, Pf18137, Pf19675"	"23595"	"ENSG00000135336"	"ORC3"	"A2A2T5; B4E025; hsa:23595; Q13565; Q53GY6; Q5T159; Q6IUY7; Q86TN5; Q9UBD5; Q9UG44; Q9UNT6"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Activation of the pre-replicative complex; Assembly of the ORC complex at the origin of replication; Activation of ATR in response to replication stress; E2F-enabled inhibition of pre-replication complex formation; CDC6 association with the ORC:origin complex"	"10"	"0"	"153.8"	"128.8"	"170.1"	"233.4"	"157.3"	"139.9"	"318.3"	"317.7"	"466.1"	"1084.4"	"1519.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07948"	"Tyrosine-protein kinase Lyn OS=Homo sapiens OX=9606 GN=LYN PE=1 SV=3"	"0.000"	""	"9"	"3"	"6"	"3"	"512"	"58.5"	"7.11"	"1147.56"	"11.42"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"4067"	"ENSG00000254087"	"LYN"	"A0AVQ5; hsa:4067; P07948"	"IL-5 signaling pathway; RANKL/RANK signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; GDNF signaling"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling; Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCERI mediated NF-kB activation; CD22 mediated BCR regulation; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); GPVI-mediated activation cascade; Cyclin D associated events in G1; Growth hormone receptor signaling; Inactivation of CSF3 (G-CSF) signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Erythropoietin activates STAT5; Erythropoietin activates RAS; Platelet Adhesion to exposed collagen; CD209 (DC-SIGN) signaling; Dectin-2 family"	"45"	"0"	"20.1"	"9.7"	"19.6"	"40.7"	"20.0"	"23.2"	"39.7"	"42.3"	"65.9"	"175.9"	"387.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N0X4"	"Citramalyl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=CLYBL PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"3"	"340"	"37.3"	"8.73"	"1104.20"	"11.41"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03328"	"171425"	"ENSG00000125246"	"CLYBL"	"hsa:171425; Q5W0F7; Q8N0X4; Q8TDH8"	""	""	"0"	"0"	"19.3"	"17.9"	"23.7"	"34.9"	"22.7"	"32.4"	"123.4"	"153.4"	"202.6"	"424.5"	"654.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15291"	"Retinoblastoma-binding protein 5 OS=Homo sapiens OX=9606 GN=RBBP5 PE=1 SV=2"	"0.000"	""	"6"	"2"	"5"	"2"	"538"	"59.1"	"5.10"	"536.71"	"11.40"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"5929"	"ENSG00000117222"	"RBBP5"	"A8K272; hsa:5929; Q15291; Q7Z6D8; Q8NDZ7"	"Kleefstra syndrome"	"Neddylation; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; Deactivation of the beta-catenin transactivating complex; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function"	"8"	"0"	"49.9"	"32.7"	"75.2"	"87.5"	"49.9"	"55.1"	"114.4"	"103.8"	"174.4"	"612.2"	"1045.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92769"	"Histone deacetylase 2 OS=Homo sapiens OX=9606 GN=HDAC2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"6"	"2"	"488"	"55.3"	"5.91"	"1538.63"	"11.39"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00850"	"3066"	"ENSG00000196591"	"HDAC2"	"B3KRS5; B4DL58; E1P561; hsa:3066; Q5SRI8; Q5SZ86; Q8NEH4; Q92769"	"Cell cycle; Neural crest differentiation; Notch signaling; Initiation of transcription and translation elongation at the HIV-1 LTR; Ethanol effects on histone modifications; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Ciliary landscape; 7q11.23 copy number variation syndrome; SARS-CoV-2 innate immunity evasion and cell-specific immune response; TAR syndrome; Notch signaling pathway"	"Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; NoRC negatively regulates rRNA expression; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; Regulation of TP53 Activity through Acetylation; SUMOylation of chromatin organization proteins; HDACs deacetylate histones; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Regulation of PTEN gene transcription; Factors involved in megakaryocyte development and platelet production; RNA Polymerase I Transcription Initiation; p75NTR negatively regulates cell cycle via SC1; Notch-HLH transcription pathway; Regulation of MECP2 expression and activity; STAT3 nuclear events downstream of ALK signaling; EGR2 and SOX10-mediated initiation of Schwann cell myelination; MECP2 regulates neuronal receptors and channels"	"30"	"0"	"314.6"	"344.5"	"294.1"	"392.2"	"280.7"	"305.7"	"466.1"	"487.9"	"571.7"	"1451.6"	"2250.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60508"	"Pre-mRNA-processing factor 17 OS=Homo sapiens OX=9606 GN=CDC40 PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"3"	"579"	"65.5"	"7.06"	"1165.80"	"11.35"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400"	"51362"	"ENSG00000168438"	"CDC40"	"B2RBC5; hsa:51362; O60508; O75471; Q5SRN0; Q9UPG1"	"mRNA processing"	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; mRNA Splicing - Major Pathway"	"5"	"0"	"82.5"	"77.9"	"113.9"	"126.6"	"83.7"	"88.0"	"115.2"	"146.5"	"184.3"	"636.1"	"1291.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULR0"	"Pre-mRNA-splicing factor ISY1 homolog OS=Homo sapiens OX=9606 GN=ISY1 PE=1 SV=3"	"0.000"	""	"21"	"4"	"6"	"4"	"285"	"33.0"	"5.17"	"987.31"	"11.28"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf06246"	"100534599; 57461"	"ENSG00000240682"	"ISY1"	"hsa:100534599; hsa:57461; Q96IL2; Q9BT05; Q9ULR0"	""	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Major Pathway"	"5"	"0"	"189.4"	"171.9"	"257.1"	"274.7"	"193.8"	"187.5"	"306.2"	"302.6"	"418.1"	"954.3"	"1633.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y608"	"Leucine-rich repeat flightless-interacting protein 2 OS=Homo sapiens OX=9606 GN=LRRFIP2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"721"	"82.1"	"6.95"	"619.76"	"11.28"	"1"	"2"	"cell-cell signaling;signal transduction;other biological processes"	""	"other molecular function"	"Pf09738"	"9209"	"ENSG00000093167"	"LRRFIP2"	"A8K649; A8MXR0; B4DY63; hsa:9209; Q68CV3; Q9NXH5; Q9Y608"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"20.5"	"15.1"	"24.3"	"33.1"	"15.9"	"23.1"	"43.9"	"47.0"	"70.3"	"277.4"	"536.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61221"	"ATP-binding cassette sub-family E member 1 OS=Homo sapiens OX=9606 GN=ABCE1 PE=1 SV=1"	"0.000"	""	"10"	"4"	"6"	"4"	"599"	"67.3"	"8.34"	"1271.50"	"11.26"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;mitochondrion;translational apparatus;other cell component"	"enzyme regulator activity;translation activity;other molecular function"	"Pf00005, Pf00037, Pf04068"	"6059"	"ENSG00000164163"	"ABCE1"	"hsa:6059; O88793; P61221; Q13181; Q13864; Q6NR76; Q96AL0; Q96B10; Q99K66"	""	"OAS antiviral response; Interferon alpha/beta signaling"	"2"	"0"	"215.8"	"200.9"	"281.7"	"335.8"	"215.9"	"227.2"	"436.9"	"489.9"	"687.2"	"1385.5"	"1535.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18859"	"ATP synthase-coupling factor 6, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PF PE=1 SV=1"	"0.000"	""	"29"	"2"	"3"	"2"	"108"	"12.6"	"9.52"	"286.99"	"11.25"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05511"	"522"	"ENSG00000154723"	"ATP5PF"	"hsa:522; J3KQ83; P18859"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"193.4"	"162.1"	"192.3"	"211.2"	"178.2"	"174.9"	"247.3"	"258.4"	"276.4"	"497.3"	"674.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01780"	"Exosome component 10 OS=Homo sapiens OX=9606 GN=EXOSC10 PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"885"	"100.8"	"8.46"	"1026.26"	"11.23"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00570, Pf01612, Pf08066"	"5394"	"ENSG00000171824"	"EXOSC10"	"B1AKQ0; B1AKQ1; hsa:5394; Q01780; Q15158"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"75.4"	"91.6"	"78.4"	"108.8"	"76.4"	"84.8"	"153.0"	"171.9"	"205.1"	"382.9"	"426.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75717"	"WD repeat and HMG-box DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=WDHD1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1129"	"125.9"	"5.62"	"1050.85"	"11.20"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf12341, Pf12894"	"11169"	"ENSG00000198554"	"WDHD1"	"C9JW18; F6W0U7; hsa:11169; O75717"	"Mesodermal commitment pathway"	""	"1"	"0"	"128.2"	"108.3"	"130.7"	"146.5"	"122.8"	"142.6"	"207.3"	"229.1"	"321.7"	"893.6"	"1281.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEM1"	"Nuclear pore membrane glycoprotein 210 OS=Homo sapiens OX=9606 GN=NUP210 PE=1 SV=3"	"0.000"	""	"2"	"4"	"8"	"4"	"1887"	"205.0"	"6.81"	"1145.68"	"11.19"	"4"	"4"	"transport"	"other membranes;ER/Golgi;nucleus"	""	"Pf02368"	"23225"	"ENSG00000132182"	"NUP210"	"A6NN56; hsa:23225; O94980; Q6NXG6; Q8NBJ1; Q8TEM1; Q9H6C8; Q9UFP3"	""	"ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; snRNP Assembly; HCMV Late Events; HCMV Early Events; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses"	"28"	"0"	"27.4"	"16.4"	"31.0"	"40.9"	"18.9"	"19.0"	"32.1"	"45.6"	"52.4"	"161.1"	"328.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVM9"	"Integrator complex subunit 13 OS=Homo sapiens OX=9606 GN=INTS13 PE=1 SV=2"	"0.000"	""	"9"	"4"	"5"	"4"	"706"	"80.2"	"6.70"	"775.69"	"11.19"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf10221"	"55726"	"ENSG00000064102"	"INTS13"	"B4DNK1; hsa:55726; Q86WE2; Q96HM2; Q9BTX2; Q9NTB6; Q9NVM5; Q9NVM9"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"54.4"	"57.5"	"55.8"	"63.1"	"49.6"	"51.3"	"92.2"	"106.5"	"185.1"	"578.7"	"804.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52907"	"F-actin-capping protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=CAPZA1 PE=1 SV=3"	"0.000"	""	"15"	"2"	"3"	"2"	"286"	"32.9"	"5.69"	"416.93"	"11.18"	"1"	"2"	"cell organization and biogenesis"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"829"	"ENSG00000116489"	"CAPZA1"	"hsa:829; P52907; Q53FQ6; Q6FHD5"	""	"Sensory processing of sound by inner hair cells of the cochlea; MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"8"	"0"	"40.3"	"42.7"	"46.4"	"60.1"	"37.9"	"45.3"	"69.7"	"92.0"	"116.9"	"284.0"	"407.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95785"	"Protein Wiz OS=Homo sapiens OX=9606 GN=WIZ PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"2"	"1651"	"178.6"	"6.86"	"1144.72"	"11.18"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"58525"	"ENSG00000011451"	"WIZ"	"B3KVH1; B7ZM82; hsa:58525; M0QY21; O95785; Q4G0E0; Q6P6B0; Q6ZN24; Q7LDY6; Q7LDZ1; Q96IG5; Q96SQ6; Q9BUR8; Q9NPT1"	""	""	"0"	"0"	"33.8"	"26.1"	"39.6"	"45.9"	"32.3"	"34.5"	"52.9"	"46.8"	"52.3"	"77.7"	"97.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A2RTX5"	"Threonine--tRNA ligase 2, cytoplasmic OS=Homo sapiens OX=9606 GN=TARS3 PE=1 SV=1"	"0.000"	""	"6"	"4"	"6"	"2"	"802"	"92.6"	"6.05"	"728.12"	"11.17"	"2"	"4"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"123283"	"ENSG00000185418"	"TARS3"	"A2RTX5; B2RMP7; hsa:123283; Q6B0A1; Q6IS76; Q96LW3; Q96MP4"	""	""	"0"	"0"	"62.7"	"53.1"	"64.1"	"86.3"	"57.2"	"63.5"	"104.6"	"112.1"	"144.0"	"372.4"	"469.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P24941"	"Cyclin-dependent kinase 2 OS=Homo sapiens OX=9606 GN=CDK2 PE=1 SV=2"	"0.000"	""	"15"	"4"	"8"	"3"	"298"	"33.9"	"8.68"	"1349.23"	"11.15"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1017"	"ENSG00000123374"	"CDK2"	"A8K7C6; hsa:1017; O75100; P24941"	"miRNA regulation of DNA damage response; Cell cycle; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Oncostatin M signaling pathway; Spinal cord injury; Retinoblastoma gene in cancer; Aryl hydrocarbon receptor pathway; Vitamin D receptor pathway; PI3K-Akt signaling pathway; G1 to S cell cycle control; Measles virus infection; Small cell lung cancer; DNA replication; p53 transcriptional gene network; Pleural mesothelioma; Sphingolipid metabolism in senescence; Urotensin-II-mediated signaling pathway; ID signaling pathway; TROP2 regulatory signaling; DNA damage response"	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; Regulation of TP53 Degradation; SCF(Skp2)-mediated degradation of p27/p21; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; G2 Phase; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); Telomere Extension By Telomerase; Regulation of APC/C activators between G1/S and early anaphase; Senescence-Associated Secretory Phenotype (SASP); Factors involved in megakaryocyte development and platelet production; Processing of DNA double-strand break ends; Cyclin A/B1/B2 associated events during G2/M transition; Meiotic recombination; DNA Damage/Telomere Stress Induced Senescence; Transcriptional regulation of granulopoiesis; G0 and Early G1; Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes; p53-Dependent G1 DNA Damage Response; PTK6 Regulates Cell Cycle"	"47"	"1"	"138.9"	"129.8"	"167.3"	"214.9"	"145.6"	"130.6"	"332.6"	"349.8"	"565.5"	"1871.3"	"2536.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96D46"	"60S ribosomal export protein NMD3 OS=Homo sapiens OX=9606 GN=NMD3 PE=1 SV=1"	"0.000"	""	"6"	"3"	"5"	"3"	"503"	"57.6"	"7.14"	"852.42"	"11.14"	"2"	"3"	"transport;other biological processes"	"nucleus;other cell component"	"translation activity;other molecular function"	"Pf04981"	"51068"	"ENSG00000169251"	"NMD3"	"D3DNM7; hsa:51068; Q96D46; Q9Y2Z6"	""	""	"0"	"0"	"34.5"	"39.5"	"42.1"	"45.2"	"36.4"	"41.5"	"100.2"	"91.0"	"164.2"	"693.3"	"981.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPY6"	"Wiskott-Aldrich syndrome protein family member 3 OS=Homo sapiens OX=9606 GN=WASF3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"6"	"1"	"502"	"55.3"	"6.43"	"1223.78"	"11.09"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"10810"	"ENSG00000132970"	"WASF3"	"hsa:10810; O94974; Q86VQ2; Q9UPY6"	""	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC1 GTPase cycle; VEGFA-VEGFR2 Pathway"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07195"	"L-lactate dehydrogenase B chain OS=Homo sapiens OX=9606 GN=LDHB PE=1 SV=2"	"0.000"	""	"9"	"3"	"6"	"3"	"334"	"36.6"	"6.05"	"1221.43"	"11.05"	"3"	"3"	"other metabolic processes"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3945"	"ENSG00000111716"	"LDHB"	"hsa:3945; P07195"	"Clear cell renal cell carcinoma pathways; CCL18 signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Pyruvate metabolism"	"5"	"0"	"365.2"	"369.5"	"510.5"	"1002.3"	"283.7"	"289.2"	"549.4"	"594.7"	"651.4"	"1283.5"	"1410.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WW8"	"Cytochrome c oxidase assembly factor 5 OS=Homo sapiens OX=9606 GN=COA5 PE=1 SV=1"	"0.000"	""	"54"	"3"	"5"	"3"	"74"	"8.4"	"8.68"	"943.17"	"10.99"	"2"	"3"	"cell organization and biogenesis"	"mitochondrion"	""	"Pf10203"	"493753"	"ENSG00000183513"	"COA5"	"hsa:493753; Q86WW8"	""	""	"0"	"0"	"232.6"	"288.3"	"191.7"	"197.0"	"196.6"	"28.9"	"501.6"	"636.0"	"697.2"	"878.1"	"831.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05114"	"Non-histone chromosomal protein HMG-14 OS=Homo sapiens OX=9606 GN=HMGN1 PE=1 SV=3"	"0.000"	""	"21"	"2"	"8"	"2"	"100"	"10.7"	"9.60"	"1323.16"	"10.96"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"3150"	"ENSG00000205581"	"HMGN1"	"hsa:3150; P05114; Q3KQR8"	"ATM signaling in development and disease ; p38 MAPK signaling pathway; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"8"	"0"	"482.6"	"428.0"	"469.3"	"469.0"	"430.6"	"475.8"	"576.0"	"592.6"	"751.8"	"763.1"	"512.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95881"	"Thioredoxin domain-containing protein 12 OS=Homo sapiens OX=9606 GN=TXNDC12 PE=1 SV=1"	"0.000"	""	"22"	"3"	"5"	"3"	"172"	"19.2"	"5.40"	"964.77"	"10.93"	"2"	"3"	"other biological processes"	"ER/Golgi"	"other molecular function"	"Pf13899"	"51060"	"ENSG00000117862"	"TXNDC12"	"B3KQS0; hsa:51060; O95881; Q5T1T4; Q96H50"	""	""	"0"	"0"	"294.3"	"268.6"	"343.2"	"396.5"	"328.9"	"276.8"	"422.0"	"406.7"	"491.0"	"733.9"	"985.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52435"	"DNA-directed RNA polymerase II subunit RPB11-a OS=Homo sapiens OX=9606 GN=POLR2J PE=1 SV=1"	"0.000"	""	"26"	"2"	"3"	"2"	"117"	"13.3"	"5.86"	"294.41"	"10.88"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13656"	"5439"	"ENSG00000005075"	"POLR2J"	"A5D6V8; hsa:5439; O43375; P52435"	"Pyrimidine metabolism; Eukaryotic transcription initiation"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"43"	"0"	"79.7"	"92.7"	"124.1"	"145.0"	"68.9"	"92.5"	"134.4"	"145.4"	"205.0"	"546.2"	"713.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND56"	"Protein LSM14 homolog A OS=Homo sapiens OX=9606 GN=LSM14A PE=1 SV=3"	"0.000"	""	"11"	"5"	"8"	"4"	"463"	"50.5"	"9.52"	"1129.31"	"10.88"	"4"	"4"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"26065"	"ENSG00000257103; ENSG00000262860"	"LSM14A"	"B4DTG6; hsa:26065; Q76LX7; Q8ND56; Q96AR3; Q96K73; Q96SN5; Q9UFR3"	""	""	"0"	"0"	"168.1"	"170.4"	"209.7"	"250.8"	"195.4"	"183.2"	"290.2"	"313.3"	"378.4"	"739.1"	"942.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06587"	"E3 ubiquitin-protein ligase RING1 OS=Homo sapiens OX=9606 GN=RING1 PE=1 SV=2"	"0.000"	""	"14"	"3"	"4"	"2"	"406"	"42.4"	"5.62"	"522.35"	"10.86"	"1"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00097, Pf16207"	"6015"	"ENSG00000204227; ENSG00000206287; ENSG00000226788; ENSG00000228520; ENSG00000231115; ENSG00000235107"	"RING1"	"A8JZZ0; hsa:6015; Q06587; Q5JP96; Q5SQW2; Q86V19"	"Pleural mesothelioma; Notch signaling pathway"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"11"	"0"	"67.8"	"52.9"	"89.4"	"89.7"	"70.3"	"31.7"	"112.3"	"122.9"	"153.9"	"345.9"	"438.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52756"	"RNA-binding protein 5 OS=Homo sapiens OX=9606 GN=RBM5 PE=1 SV=2"	"0.000"	""	"6"	"4"	"6"	"4"	"815"	"92.1"	"6.28"	"1050.54"	"10.85"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf00641, Pf01585, Pf17780"	"10181"	"ENSG00000003756"	"RBM5"	"B2RA45; B4DM16; B4DMF9; B4DZ63; hsa:10181; P52756; Q93021; Q9BU14; Q9HDA6; Q9UKY8; Q9UL24"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"387.2"	"335.7"	"409.1"	"444.9"	"329.3"	"288.7"	"444.1"	"495.6"	"564.5"	"1090.1"	"1571.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXA9"	"Splicing regulatory glutamine/lysine-rich protein 1 OS=Homo sapiens OX=9606 GN=SREK1 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"508"	"59.3"	"10.39"	"565.71"	"10.85"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"140890"	"ENSG00000153914"	"SREK1"	"A4FTW3; hsa:140890; Q2M1J0; Q86X37; Q8WXA9"	"mRNA processing"	""	"1"	"0"	"218.9"	"156.2"	"213.2"	"248.2"	"170.7"	"208.8"	"329.3"	"339.2"	"509.2"	"1300.7"	"1915.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75530"	"Polycomb protein EED OS=Homo sapiens OX=9606 GN=EED PE=1 SV=2"	"0.000"	""	"5"	"2"	"6"	"2"	"441"	"50.2"	"7.03"	"990.70"	"10.84"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400"	"8726"	"ENSG00000074266"	"EED"	"A8K7V5; hsa:8726; O00149; O75530; Q6NTH2; Q7LDA5; Q7LDG8; Q86VV2; Q9UNY7"	"Histone modifications; Interactome of polycomb repressive complex 2 (PRC2) ; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma; 5q35 copy number variation"	"Transcriptional Regulation by E2F6; HCMV Early Events; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA; Defective pyroptosis"	"15"	"0"	"54.1"	"44.5"	"76.4"	"86.1"	"56.6"	"61.9"	"108.9"	"117.7"	"193.6"	"652.4"	"831.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUD2"	"ELKS/Rab6-interacting/CAST family member 1 OS=Homo sapiens OX=9606 GN=ERC1 PE=1 SV=1"	"0.000"	""	"4"	"3"	"5"	"3"	"1116"	"128.0"	"5.97"	"776.08"	"10.81"	"2"	"3"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf09457, Pf10174"	"23085"	"ENSG00000082805"	"ERC1"	"A2RU77; A7E295; D3DUP7; D3DUP8; hsa:23085; Q6NVK2; Q8IUD2; Q8IUD3; Q8IUD4; Q8IUD5; Q8NAS1; Q9NXN5; Q9UIK7; Q9UPS1"	""	""	"0"	"0"	"65.3"	"51.1"	"70.2"	"91.0"	"75.2"	"64.6"	"116.0"	"114.3"	"164.3"	"347.9"	"466.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25685"	"DnaJ homolog subfamily B member 1 OS=Homo sapiens OX=9606 GN=DNAJB1 PE=1 SV=4"	"0.000"	""	"15"	"5"	"8"	"4"	"340"	"38.0"	"8.63"	"1430.12"	"10.81"	"4"	"4"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00226, Pf01556"	"3337"	"ENSG00000132002"	"DNAJB1"	"B4DX52; hsa:3337; P25685"	"Nuclear receptors meta-pathway; NRF2 pathway"	"MAPK6/MAPK4 signaling; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Regulation of HSF1-mediated heat shock response; Attenuation phase"	"7"	"1"	"512.5"	"463.3"	"565.0"	"689.5"	"490.6"	"455.2"	"739.7"	"775.1"	"883.0"	"1499.0"	"1839.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07311"	"Acylphosphatase-1 OS=Homo sapiens OX=9606 GN=ACYP1 PE=1 SV=2"	"0.000"	""	"44"	"3"	"5"	"3"	"99"	"11.3"	"9.31"	"528.65"	"10.80"	"2"	"3"	"other metabolic processes"	""	"other molecular function"	"Pf00708"	"97"	"ENSG00000119640"	"ACYP1"	"A6NDV8; B2R590; hsa:97; P07311"	""	""	"0"	"0"	"67.4"	"56.1"	"81.6"	"83.7"	"69.5"	"86.7"	"236.4"	"251.9"	"390.4"	"783.1"	"972.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Q4"	"Non-homologous end-joining factor 1 OS=Homo sapiens OX=9606 GN=NHEJ1 PE=1 SV=1"	"0.000"	""	"12"	"2"	"4"	"2"	"299"	"33.3"	"5.97"	"1133.36"	"10.74"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09302"	"79840"	"ENSG00000187736"	"NHEJ1"	"B8ZZA4; hsa:79840; Q4ZFW7; Q6IA64; Q96JS9; Q9H9Q4"	"Non-homologous end joining; DNA repair pathways, full network"	"Nonhomologous End-Joining (NHEJ)"	"3"	"0"	"93.1"	"87.8"	"97.6"	"116.7"	"80.7"	"102.5"	"262.8"	"280.7"	"460.3"	"868.1"	"876.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61088"	"Ubiquitin-conjugating enzyme E2 N OS=Homo sapiens OX=9606 GN=UBE2N PE=1 SV=1"	"0.000"	""	"31"	"3"	"6"	"3"	"152"	"17.1"	"6.57"	"1320.50"	"10.72"	"3"	"3"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"7334"	"ENSG00000177889"	"UBE2N"	"hsa:7334; P61088; Q16781; Q53Y81"	"IL-1 signaling pathway; Interleukin-1 induced activation of NF-kB; MYD88 distinct input-output pathway; Prader-Willi and Angelman syndrome; 3q29 copy number variation syndrome"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; FCERI mediated NF-kB activation; Downstream TCR signaling; E3 ubiquitin ligases ubiquitinate target proteins; Antigen processing: Ubiquitination & Proteasome degradation; CLEC7A (Dectin-1) signaling; Aggrephagy; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; IKK complex recruitment mediated by RIP1; JNK (c-Jun kinases) phosphorylation and  activation mediated by activated human TAK1; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; NOD1/2 Signaling Pathway; TICAM1, RIP1-mediated IKK complex recruitment; TAK1-dependent IKK and NF-kappa-B activation  ; IRAK1 recruits IKK complex; IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation; activated TAK1 mediates p38 MAPK activation; Nonhomologous End-Joining (NHEJ); Formation of Incision Complex in GG-NER; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling"	"28"	"0"	"42.5"	"39.0"	"69.7"	"86.4"	"57.1"	"48.0"	"91.1"	"86.2"	"123.7"	"742.7"	"1986.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RT1"	"Erbin OS=Homo sapiens OX=9606 GN=ERBIN PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1412"	"158.2"	"5.50"	"999.59"	"10.72"	"3"	"3"	"cell adhesion;cell organization and biogenesis;transport;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf00595, Pf13855"	"55914"	"ENSG00000112851"	"ERBIN"	"A0AVR1; B4E3F1; B7ZLV9; E7EQW9; E9PCR8; hsa:55914; Q1RMD0; Q86W38; Q96RT1; Q9NR18; Q9NW48; Q9ULJ5"	"Nucleotide-binding oligomerization domain (NOD) pathway; Nod-like receptor (NLR) signaling pathway; Pathways affected in adenoid cystic carcinoma"	"RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Downregulation of ERBB2 signaling; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"26"	"0"	"20.9"	"21.1"	"28.0"	"44.4"	"21.5"	"24.4"	"45.3"	"45.4"	"68.0"	"178.0"	"214.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43897"	"Elongation factor Ts, mitochondrial OS=Homo sapiens OX=9606 GN=TSFM PE=1 SV=2"	"0.000"	""	"15"	"4"	"5"	"4"	"325"	"35.4"	"8.38"	"273.79"	"10.72"	"1"	"4"	"protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf00889"	"10102"	"ENSG00000123297"	"TSFM"	"B4E391; F5H2T7; hsa:10102; P43897; Q561V7; Q8TBC2; Q9UQK0"	""	"Mitochondrial translation elongation"	"1"	"0"	"83.9"	"75.7"	"113.1"	"132.2"	"84.1"	"101.7"	"212.1"	"220.5"	"370.6"	"1642.2"	"2120.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18615"	"Negative elongation factor E OS=Homo sapiens OX=9606 GN=NELFE PE=1 SV=3"	"0.000"	""	"13"	"3"	"5"	"3"	"380"	"43.2"	"9.33"	"1715.38"	"10.70"	"2"	"1"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"7936"	"ENSG00000204356; ENSG00000206268; ENSG00000206357; ENSG00000229363; ENSG00000231044; ENSG00000233801"	"NELFE"	"A2BE08; B4DUN1; B4DYX9; hsa:7936; P18615; Q5JP74; Q5JP75; Q96F56; Q9NPK2"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	"160.5"	"141.8"	"157.2"	"222.6"	"150.2"	"137.9"	"294.5"	"328.7"	"502.5"	"1282.1"	"1486.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00161"	"Synaptosomal-associated protein 23 OS=Homo sapiens OX=9606 GN=SNAP23 PE=1 SV=1"	"0.000"	""	"21"	"2"	"3"	"2"	"211"	"23.3"	"5.01"	"522.00"	"10.70"	"1"	"2"	"cell-cell signaling;cell organization and biogenesis;stress response;transport"	"plasma membrane;other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00835"	"8773"	"ENSG00000092531"	"SNAP23"	"hsa:8773; O00161; O00162; Q13602; Q6IAE3"	"Insulin signaling"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; RAC3 GTPase cycle; RHOB GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; Neutrophil degranulation; trans-Golgi Network Vesicle Budding"	"13"	"0"	"42.4"	"42.5"	"62.8"	"84.5"	"42.1"	"57.0"	"80.9"	"83.5"	"118.5"	"280.1"	"382.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99590"	"Protein SCAF11 OS=Homo sapiens OX=9606 GN=SCAF11 PE=1 SV=2"	"0.000"	""	"4"	"4"	"7"	"4"	"1463"	"164.6"	"8.41"	"1577.03"	"10.69"	"4"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	""	"9169"	"ENSG00000139218"	"SCAF11"	"A6NEU9; A6NLW5; hsa:9169; Q8IW59; Q99590"	"Apoptosis"	""	"1"	"0"	"180.1"	"174.7"	"203.7"	"250.6"	"176.3"	"175.3"	"265.1"	"268.7"	"317.9"	"570.5"	"790.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63151"	"Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform OS=Homo sapiens OX=9606 GN=PPP2R2A PE=1 SV=1"	"0.000"	""	"8"	"3"	"6"	"3"	"447"	"51.7"	"6.20"	"985.82"	"10.62"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	""	"5520"	"ENSG00000221914"	"PPP2R2A"	"B2RBU8; B4E1T7; hsa:5520; P50409; P63151; Q00007"	"Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation"	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Initiation of Nuclear Envelope (NE) Reformation"	"7"	"0"	"120.7"	"113.4"	"128.8"	"151.0"	"127.8"	"128.0"	"184.9"	"170.4"	"171.8"	"474.2"	"984.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NV70"	"Exocyst complex component 1 OS=Homo sapiens OX=9606 GN=EXOC1 PE=1 SV=4"	"0.000"	""	"4"	"3"	"6"	"3"	"894"	"101.9"	"6.61"	"1409.53"	"10.61"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf09763, Pf15277"	"55763"	"ENSG00000090989"	"EXOC1"	"hsa:55763; Q504V4; Q8WUE7; Q96T15; Q9NV70; Q9NZE4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"27.4"	"33.9"	"50.3"	"44.9"	"39.7"	"71.1"	"138.7"	"180.8"	"268.7"	"673.7"	"774.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4G4"	"Golgi-associated plant pathogenesis-related protein 1 OS=Homo sapiens OX=9606 GN=GLIPR2 PE=1 SV=3"	"0.000"	""	"17"	"2"	"6"	"2"	"154"	"17.2"	"9.41"	"1464.33"	"10.60"	"2"	"2"	"other biological processes"	"non-structural extracellular;other membranes;ER/Golgi"	"other molecular function"	"Pf00188"	"152007"	"ENSG00000122694"	"GLIPR2"	"hsa:152007; Q5VZR1; Q8N2S6; Q8WWC9; Q8WX36; Q9H4G4"	""	""	"0"	"0"	"218.5"	"232.6"	"228.9"	"291.7"	"208.3"	"230.6"	"365.0"	"387.2"	"415.3"	"728.3"	"950.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60749"	"Sorting nexin-2 OS=Homo sapiens OX=9606 GN=SNX2 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"2"	"519"	"58.4"	"5.12"	"679.48"	"10.52"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6643"	"ENSG00000205302"	"SNX2"	"B3KN44; B4DEK4; B7Z408; hsa:6643; O43650; O60749; P82862; Q53XK8; Q597H6; Q9BTS8"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"81.2"	"78.1"	"86.9"	"114.2"	"85.5"	"86.8"	"177.8"	"187.4"	"310.2"	"1132.9"	"2028.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQT4"	"Exosome complex component RRP46 OS=Homo sapiens OX=9606 GN=EXOSC5 PE=1 SV=1"	"0.000"	""	"14"	"3"	"6"	"3"	"235"	"25.2"	"7.59"	"1254.58"	"10.51"	"3"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"56915"	"ENSG00000077348"	"EXOSC5"	"hsa:56915; Q32Q81; Q8NG16; Q96I89; Q9NQT4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"211.3"	"205.8"	"288.0"	"291.3"	"207.9"	"251.8"	"345.3"	"319.2"	"414.9"	"1113.7"	"1967.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62861"	"40S ribosomal protein S30 OS=Homo sapiens OX=9606 GN=FAU PE=1 SV=1"	"0.000"	""	"20"	"3"	"6"	"3"	"59"	"6.6"	"12.15"	"1106.03"	"10.50"	"3"	"3"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf04758"	""	"ENSCHIG00000017446; ENSJHYG00000000624; ENSLLEG00000000574"	"Fau; FAU"	"A0A452F0A8; A0A7L0YXB0; A0A8C5IE60; A0A8C5LQJ8; P0C2F0; P62860; P62863; P62864; P62866; P62867; Q05472; Q5RC12; Q8HYI8; Q920W7; Q95261"	""	""	"0"	"0"	"379.1"	"371.3"	"455.9"	"502.9"	"418.6"	"399.6"	"528.9"	"513.8"	"587.2"	"1088.1"	"1298.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXF0"	"Serine/arginine-rich splicing factor 12 OS=Homo sapiens OX=9606 GN=SRSF12 PE=2 SV=1"	"0.000"	""	"9"	"3"	"6"	"1"	"261"	"30.5"	"11.69"	"1337.47"	"10.48"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00076"	"135295"	"ENSG00000154548"	"SRSF12"	"B2RA22; hsa:135295; Q5T7K0; Q8WW25; Q8WXF0"	""	"mRNA Splicing - Major Pathway; Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"49.5"	"62.0"	"36.4"	"75.4"	"46.8"	"47.4"	"81.1"	"106.1"	"80.8"	"184.9"	"204.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A5YKK6"	"CCR4-NOT transcription complex subunit 1 OS=Homo sapiens OX=9606 GN=CNOT1 PE=1 SV=2"	"0.000"	""	"2"	"3"	"4"	"3"	"2376"	"266.8"	"7.11"	"404.86"	"10.48"	"1"	"3"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04054, Pf12842, Pf16415, Pf16417, Pf16418"	"23019"	"ENSG00000125107"	"CNOT1"	"A5YKK6; hsa:23019; Q68DX7; Q7Z3K2; Q8IWB8; Q8TB53; Q9BVZ6; Q9UFR8; Q9UI27; Q9Y2L0"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"71.7"	"58.7"	"92.0"	"104.3"	"70.7"	"85.2"	"114.1"	"130.2"	"180.3"	"302.9"	"418.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5S2"	"Serine/threonine-protein kinase MRCK beta OS=Homo sapiens OX=9606 GN=CDC42BPB PE=1 SV=2"	"0.000"	""	"3"	"4"	"6"	"3"	"1711"	"194.2"	"6.37"	"805.68"	"10.47"	"3"	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00780, Pf08826, Pf15796"	"9578"	"ENSG00000198752"	"CDC42BPB"	"A9JR72; hsa:9578; Q2L7A5; Q86TJ1; Q9ULU5; Q9Y5S2"	"VEGFA-VEGFR2 signaling; 15q11q13 copy number variation"	"CDC42 GTPase cycle; RHOQ GTPase cycle; RHOJ GTPase cycle"	"5"	"0"	"111.4"	"78.9"	"154.2"	"160.8"	"118.0"	"112.0"	"356.7"	"360.0"	"509.5"	"1531.2"	"2449.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92890"	"Ubiquitin recognition factor in ER-associated degradation protein 1 OS=Homo sapiens OX=9606 GN=UFD1 PE=1 SV=3"	"0.000"	""	"8"	"3"	"6"	"3"	"307"	"34.5"	"6.70"	"1258.88"	"10.47"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03152"	"7353"	"ENSG00000070010"	"UFD1"	"A8MW31; hsa:7353; Q92890; Q9Y5N0"	"22q11.2 copy number variation syndrome"	"Ub-specific processing proteases; Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"5"	"0"	"242.0"	"216.4"	"260.9"	"309.4"	"229.6"	"239.0"	"343.1"	"371.1"	"496.0"	"1330.4"	"1902.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXB1"	"DnaJ homolog subfamily C member 10 OS=Homo sapiens OX=9606 GN=DNAJC10 PE=1 SV=2"	"0.000"	""	"4"	"2"	"5"	"2"	"793"	"91.0"	"7.18"	"580.41"	"10.44"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi"	"other molecular function"	"Pf00085, Pf00226"	"54431"	"ENSG00000077232"	"DNAJC10"	"hsa:54431; Q17RJ6; Q3B7W8; Q4ZG06; Q53QT7; Q6UWZ6; Q86T61; Q8IXB1; Q8NC82; Q8TD87; Q96K38; Q96K44; Q96K54; Q9NSY6"	""	""	"0"	"0"	"44.0"	"47.9"	"56.7"	"74.7"	"41.6"	"51.7"	"66.9"	"86.2"	"107.7"	"193.2"	"219.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P59998"	"Actin-related protein 2/3 complex subunit 4 OS=Homo sapiens OX=9606 GN=ARPC4 PE=1 SV=3"	"0.000"	""	"21"	"4"	"7"	"4"	"168"	"19.7"	"8.43"	"1110.90"	"10.44"	"3"	"4"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf05856"	"10093"	"ENSG00000241553"	"ARPC4"	"C9JWM7; E7ETI0; F6TTL5; hsa:10093; O15509; P59998; Q6P0W5; Q96QJ3"	"Pathogenic Escherichia coli infection"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Clathrin-mediated endocytosis; EPHB-mediated forward signaling"	"6"	"0"	"123.8"	"111.0"	"117.2"	"140.0"	"111.7"	"108.5"	"293.7"	"300.6"	"649.4"	"1681.1"	"2034.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H425"	"Uncharacterized protein C1orf198 OS=Homo sapiens OX=9606 GN=C1orf198 PE=1 SV=1"	"0.000"	""	"7"	"2"	"5"	"2"	"327"	"36.3"	"5.72"	"1003.08"	"10.42"	"1"	"2"	""	"cytosol"	""	"Pf15797"	"84886"	"ENSG00000119280"	"C1orf198"	"A8K8R8; B3KTW1; G5EA08; hsa:84886; Q9H425"	""	""	"0"	"0"	"43.2"	"34.1"	"45.5"	"67.3"	"36.9"	"43.2"	"70.7"	"71.9"	"84.3"	"150.0"	"192.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14C86"	"GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1478"	"164.9"	"5.22"	"840.25"	"10.42"	"3"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00616, Pf02204, Pf18151"	"26130"	"ENSG00000165219"	"GAPVD1"	"A8MYK3; B0QZ62; B0QZ63; B0QZ64; hsa:26130; Q14C76; Q14C86; Q2Q1W1; Q8ND92; Q8WU86; Q96CZ4; Q9NXQ1; Q9P207; Q9Y4N0"	""	"RAB GEFs exchange GTP for GDP on RABs; Clathrin-mediated endocytosis"	"2"	"0"	"100.6"	"85.8"	"110.6"	"121.7"	"94.8"	"91.4"	"142.3"	"165.0"	"198.1"	"413.7"	"698.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60866"	"40S ribosomal protein S20 OS=Homo sapiens OX=9606 GN=RPS20 PE=1 SV=1"	"0.000"	""	"26"	"3"	"6"	"3"	"119"	"13.4"	"9.94"	"972.95"	"10.40"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00338"	"6224"	"ENSG00000008988"	"RPS20"	"B2R4F4; B4DW28; hsa:6224; P17075; P60866; Q5M8S9"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; SARS-CoV-2 modulates host translation machinery; SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"297.5"	"315.1"	"345.1"	"497.2"	"284.7"	"255.5"	"470.6"	"510.6"	"607.5"	"983.5"	"1078.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14696"	"LRP chaperone MESD OS=Homo sapiens OX=9606 GN=MESD PE=1 SV=2"	"0.000"	""	"16"	"3"	"6"	"3"	"234"	"26.1"	"7.78"	"1353.05"	"10.38"	"3"	"3"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi"	"signal transduction activity or receptor binding;other molecular function"	"Pf10185"	"23184"	"ENSG00000117899"	"MESD"	"B4DW84; D3DW96; hsa:23184; Q14696; Q969U1"	""	""	"0"	"0"	"107.6"	"104.8"	"120.2"	"144.4"	"102.0"	"106.5"	"493.7"	"529.5"	"970.1"	"1930.1"	"2389.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0K7"	"Ankycorbin OS=Homo sapiens OX=9606 GN=RAI14 PE=1 SV=2"	"0.000"	""	"3"	"3"	"7"	"2"	"980"	"110.0"	"6.21"	"1424.40"	"10.33"	"3"	"2"	"other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00023, Pf12796"	"26064"	"ENSG00000039560"	"RAI14"	"E9PED3; hsa:26064; Q6V1W9; Q7Z5I4; Q7Z733; Q9P0K7; Q9P2L2; Q9Y3T5"	""	""	"0"	"0"	"98.2"	"102.4"	"109.3"	"131.9"	"93.1"	"112.8"	"167.1"	"161.2"	"216.9"	"452.9"	"557.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6Y8"	"SEC23-interacting protein OS=Homo sapiens OX=9606 GN=SEC23IP PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"1000"	"111.0"	"5.54"	"1108.16"	"10.33"	"2"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00536, Pf02862"	"11196"	"ENSG00000107651"	"SEC23IP"	"D3DRD2; hsa:11196; Q8IXH5; Q9BUK5; Q9Y6Y8"	""	"COPII-mediated vesicle transport"	"1"	"0"	"248.6"	"187.1"	"211.3"	"260.3"	"188.9"	"215.1"	"279.6"	"285.3"	"326.6"	"429.5"	"466.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZR7"	"ATP-dependent RNA helicase DDX24 OS=Homo sapiens OX=9606 GN=DDX24 PE=1 SV=1"	"0.000"	""	"4"	"3"	"6"	"3"	"859"	"96.3"	"9.06"	"950.83"	"10.27"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271"	"57062"	"ENSG00000089737; ENSG00000273761"	"DDX24"	"E7EMJ4; hsa:57062; Q4V9L5; Q9GZR7"	""	""	"0"	"0"	"9.3"	"5.3"	"22.9"	"10.2"	"10.6"	"10.5"	"8.5"	"11.7"	"11.9"	"24.7"	"25.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6R4"	"Nucleolar protein 6 OS=Homo sapiens OX=9606 GN=NOL6 PE=1 SV=2"	"0.000"	""	"3"	"3"	"6"	"3"	"1146"	"127.5"	"7.64"	"896.60"	"10.24"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	""	"Pf03813, Pf17403, Pf17404, Pf17405, Pf17406, Pf17407"	"65083"	"ENSG00000165271"	"NOL6"	"hsa:65083; Q5T5M3; Q5T5M4; Q7L4G6; Q8N6I0; Q8TEY9; Q8TEZ0; Q8TEZ1; Q9H675; Q9H6R4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"160.7"	"157.4"	"177.8"	"208.9"	"153.7"	"155.4"	"291.7"	"328.3"	"374.8"	"751.6"	"1056.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0U3"	"Sentrin-specific protease 1 OS=Homo sapiens OX=9606 GN=SENP1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"644"	"73.4"	"8.47"	"966.00"	"10.21"	"3"	"3"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf02902"	"29843"	"ENSG00000079387"	"SENP1"	"A8K7P5; hsa:29843; Q86XC8; Q9P0U3"	""	"RHOF GTPase cycle; SUMO is proteolytically processed"	"2"	"0"	"186.8"	"170.5"	"218.3"	"237.9"	"180.0"	"172.2"	"275.0"	"300.5"	"347.8"	"667.3"	"964.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96A65"	"Exocyst complex component 4 OS=Homo sapiens OX=9606 GN=EXOC4 PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"3"	"974"	"110.4"	"6.49"	"1104.69"	"10.21"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf04048"	"60412"	"ENSG00000131558"	"EXOC4"	"E9PED2; hsa:60412; Q541U8; Q96A65; Q9C0G4; Q9H9K0; Q9P102"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"85.6"	"75.2"	"121.8"	"109.9"	"80.8"	"97.1"	"350.3"	"409.1"	"618.4"	"943.2"	"970.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75970"	"Multiple PDZ domain protein OS=Homo sapiens OX=9606 GN=MPDZ PE=1 SV=2"	"0.000"	""	"2"	"3"	"6"	"3"	"2070"	"221.5"	"5.06"	"929.00"	"10.20"	"3"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf00595, Pf09045, Pf16667"	"8777"	"ENSG00000107186"	"MPDZ"	"A6NLC2; B2RTS3; B7ZMI4; hsa:8777; O43798; O75970; Q4LE30; Q5CZ80; Q5JTX3; Q5JTX6; Q5JTX7; Q5JUC3; Q5JUC4; Q5VZ62; Q8N790"	""	""	"0"	"0"	"221.0"	"206.1"	"240.1"	"322.2"	"189.3"	"180.1"	"402.0"	"411.0"	"530.4"	"1443.6"	"1947.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53597"	"Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLG1 PE=1 SV=4"	"0.000"	""	"9"	"2"	"4"	"2"	"346"	"36.2"	"8.79"	"959.47"	"10.18"	"2"	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf02629"	"8802"	"ENSG00000163541"	"SUCLG1"	"hsa:8802; P53597; Q9BWB0; Q9UNP6"	"Amino acid metabolism; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"3"	"0"	"40.6"	"42.9"	"45.6"	"82.0"	"60.4"	"43.9"	"84.0"	"90.5"	"128.8"	"551.2"	"1236.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Q8"	"General transcription factor 3C polypeptide 5 OS=Homo sapiens OX=9606 GN=GTF3C5 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"519"	"59.5"	"6.90"	"1125.78"	"10.16"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09734, Pf17682"	"9328"	"ENSG00000148308"	"GTF3C5"	"A6NI44; A6NJB9; hsa:9328; Q5T7U2; Q5T7U3; Q8N2U7; Q8N857; Q96GD9; Q9H4P2; Q9Y5Q8"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"58.9"	"50.9"	"58.8"	"83.4"	"55.2"	"67.4"	"99.3"	"99.9"	"121.1"	"437.6"	"753.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP1"	"Programmed cell death protein 2-like OS=Homo sapiens OX=9606 GN=PDCD2L PE=1 SV=1"	"0.000"	""	"15"	"3"	"5"	"3"	"358"	"39.4"	"4.86"	"959.14"	"10.14"	"2"	"3"	"cell cycle OR cell proliferation;other biological processes"	"other cell component"	""	"Pf04194"	"84306"	"ENSG00000126249"	"PDCD2L"	"hsa:84306; Q9BRP1"	""	""	"0"	"0"	"141.8"	"104.9"	"187.2"	"206.6"	"145.6"	"110.4"	"263.3"	"265.8"	"342.1"	"591.3"	"741.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00154"	"Cytosolic acyl coenzyme A thioester hydrolase OS=Homo sapiens OX=9606 GN=ACOT7 PE=1 SV=3"	"0.000"	""	"9"	"3"	"5"	"3"	"380"	"41.8"	"8.54"	"900.75"	"10.14"	"2"	"3"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf03061"	"11332"	"ENSG00000097021"	"ACOT7"	"A8K0K7; A8K232; A8K6B8; A8K837; B3KQ12; hsa:11332; O00154; O43703; Q53Y78; Q5JYL2; Q5JYL3; Q5JYL4; Q5JYL5; Q5JYL6; Q5TGR4; Q9UJM9; Q9Y539; Q9Y540"	""	"Mitochondrial Fatty Acid Beta-Oxidation"	"1"	"0"	"83.6"	"80.1"	"107.9"	"117.9"	"84.4"	"71.5"	"135.2"	"157.9"	"197.3"	"875.4"	"2332.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07741"	"Adenine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=APRT PE=1 SV=2"	"0.000"	""	"21"	"2"	"4"	"2"	"180"	"19.6"	"6.02"	"901.31"	"10.13"	"2"	"2"	"other metabolic processes;transport;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00156"	"353"	"ENSG00000198931"	"APRT"	"G5E9J2; hsa:353; P07741; Q3KP55; Q68DF9"	""	"Neutrophil degranulation; Purine salvage; Defective APRT disrupts adenine salvage"	"3"	"0"	"14.6"	"11.9"	"21.5"	"33.7"	"17.0"	"19.1"	"28.6"	"27.4"	"50.8"	"140.0"	"247.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50552"	"Vasodilator-stimulated phosphoprotein OS=Homo sapiens OX=9606 GN=VASP PE=1 SV=3"	"0.000"	""	"8"	"2"	"4"	"2"	"380"	"39.8"	"8.94"	"1133.68"	"10.09"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"7408"	"ENSG00000125753"	"VASP"	"B2RBT9; hsa:7408; P50552; Q6PIZ1; Q93035"	"Integrin-mediated cell adhesion; Focal adhesion"	"Generation of second messenger molecules; Signaling by ROBO receptors; Cell-extracellular matrix interactions"	"5"	"0"	"43.1"	"49.5"	"60.6"	"77.5"	"50.3"	"44.9"	"84.7"	"88.4"	"107.0"	"234.9"	"341.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UDY4"	"DnaJ homolog subfamily B member 4 OS=Homo sapiens OX=9606 GN=DNAJB4 PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"2"	"337"	"37.8"	"8.50"	"662.08"	"10.07"	"2"	"3"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf00226, Pf01556"	"11080"	"ENSG00000162616"	"DNAJB4"	"B2R824; hsa:11080; Q13431; Q9UDY4"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"40.4"	"36.3"	"37.2"	"48.4"	"40.9"	"44.1"	"48.8"	"60.6"	"84.1"	"159.8"	"204.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60900"	"Proteasome subunit alpha type-6 OS=Homo sapiens OX=9606 GN=PSMA6 PE=1 SV=1"	"0.000"	""	"15"	"3"	"4"	"3"	"246"	"27.4"	"6.76"	"490.92"	"10.07"	"1"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00227, Pf10584"	"5687"	"ENSG00000100902"	"PSMA6"	"B2R7J9; B4DQR4; B4DXJ9; hsa:5687; P34062; P60900; Q6IB60"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; Downstream TCR signaling; Neddylation; KEAP1-NFE2L2 pathway; FCERI mediated NF-kB activation; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"63.5"	"65.9"	"72.0"	"91.1"	"46.8"	"45.6"	"89.8"	"100.1"	"136.1"	"406.1"	"930.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ0"	"PRKC apoptosis WT1 regulator protein OS=Homo sapiens OX=9606 GN=PAWR PE=1 SV=1"	"0.000"	""	"12"	"3"	"4"	"3"	"340"	"36.5"	"5.41"	"757.48"	"10.06"	"2"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"5074"	"ENSG00000177425"	"PAWR"	"hsa:5074; O75796; Q6FHY9; Q8N700; Q96IZ0"	""	""	"0"	"0"	"166.4"	"133.8"	"184.9"	"231.1"	"152.5"	"152.6"	"306.8"	"283.8"	"508.8"	"1358.1"	"1676.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14186"	"Transcription factor Dp-1 OS=Homo sapiens OX=9606 GN=TFDP1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"3"	"410"	"45.0"	"6.05"	"874.13"	"10.06"	"2"	"3"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02319, Pf08781"	"7027"	"ENSG00000198176"	"TFDP1"	"B4DLQ9; hsa:7027; Q14186; Q5JSB4; Q8IZL5"	"Cell cycle; Retinoblastoma gene in cancer; G1 to S cell cycle control; DYRK1A involvement regarding cell proliferation in brain development"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Transcriptional Regulation by E2F6; Pre-NOTCH Transcription and Translation; Oncogene Induced Senescence; Cyclin D associated events in G1; Defective binding of RB1 mutants to E2F1,(E2F2, E2F3); TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Activation of PUMA and translocation to mitochondria; Transcriptional regulation of granulopoiesis; G1/S-Specific Transcription; Cyclin E associated events during G1/S transition ; Transcription of E2F targets under negative control by DREAM complex; Cyclin A:Cdk2-associated events at S phase entry; Activation of NOXA and translocation to mitochondria; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1"	"22"	"0"	"37.0"	"41.5"	"57.5"	"66.7"	"46.2"	"45.7"	"77.6"	"69.7"	"114.0"	"247.4"	"316.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60604"	"Ubiquitin-conjugating enzyme E2 G2 OS=Homo sapiens OX=9606 GN=UBE2G2 PE=1 SV=1"	""	""	"15"	"1"	"2"	"1"	"165"	"18.6"	"4.70"	""	"10.04"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf00179"	"7327"	"ENSG00000184787"	"UBE2G2"	"A6NMQ7; A8K3L4; D3DSL7; hsa:7327; P56554; P60604"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"4"	"0"	"12.5"	"12.9"	"15.2"	"21.9"	"13.7"	"10.7"	"19.9"	"22.9"	"34.6"	"86.9"	"97.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13576"	"Ras GTPase-activating-like protein IQGAP2 OS=Homo sapiens OX=9606 GN=IQGAP2 PE=1 SV=4"	"0.000"	""	"2"	"3"	"6"	"2"	"1575"	"180.5"	"5.64"	"970.80"	"10.03"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00307, Pf00612, Pf00616, Pf03836"	"10788"	"ENSG00000145703"	"IQGAP2"	"A8K4V1; B7Z8A4; hsa:10788; J3KR91; Q13576"	"Ciliary landscape; G13 signaling pathway"	"Neutrophil degranulation; RHO GTPases activate IQGAPs; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle"	"7"	"0"	"88.1"	"56.8"	"98.5"	"130.8"	"118.2"	"99.7"	"138.4"	"199.5"	"195.2"	"523.3"	"511.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51649"	"Succinate-semialdehyde dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH5A1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"535"	"57.2"	"8.28"	"377.28"	"10.03"	"1"	"2"	"other metabolic processes;developmental processes"	"mitochondrion"	"other molecular function"	"Pf00171"	"7915"	"ENSG00000112294"	"ALDH5A1"	"B2RD26; G5E949; hsa:7915; P51649; Q546H9; Q8N3W6"	"Fragile X syndrome"	"Degradation of GABA"	"2"	"0"	"21.3"	"18.2"	"26.6"	"33.7"	"22.8"	"21.3"	"51.5"	"56.9"	"81.6"	"231.5"	"428.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15910"	"Histone-lysine N-methyltransferase EZH2 OS=Homo sapiens OX=9606 GN=EZH2 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"746"	"85.3"	"7.02"	"1154.57"	"10.00"	"3"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf11616, Pf18118, Pf18264"	"2146"	"ENSG00000106462"	"EZH2"	"B2RAQ1; B3KS30; B7Z1D6; B7Z7L6; hsa:2146; Q15755; Q15910; Q75MG3; Q92857; Q96FI6"	"Cell differentiation - expanded index; Histone modifications; Endoderm differentiation; Interactome of polycomb repressive complex 2 (PRC2) ; MECP2 and associated Rett syndrome; Tumor suppressor activity of SMARCB1; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; Pleural mesothelioma"	"HCMV Early Events; Defective pyroptosis; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6; Activation of anterior HOX genes in hindbrain development during early embryogenesis; PKMTs methylate histone lysines; PRC2 methylates histones and DNA"	"19"	"0"	"170.3"	"190.7"	"182.0"	"204.8"	"161.9"	"135.7"	"257.4"	"267.9"	"351.0"	"839.7"	"947.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13618"	"Cullin-3 OS=Homo sapiens OX=9606 GN=CUL3 PE=1 SV=2"	"0.000"	""	"5"	"4"	"8"	"4"	"768"	"88.9"	"8.48"	"1218.78"	"9.98"	"4"	"4"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00888, Pf10557"	"8452"	"ENSG00000036257"	"CUL3"	"A8K536; B8ZZC3; hsa:8452; O75415; Q13618; Q569L3; Q9UBI8; Q9UET7"	"Hedgehog signaling pathway; NRF2-ARE regulation; 22q11.2 copy number variation syndrome; Head and neck squamous cell carcinoma; 1p36 copy number variation syndrome"	"Potential therapeutics for SARS; Antigen processing: Ubiquitination & Proteasome degradation; Degradation of DVL; Hedgehog 'on' state; Regulation of RAS by GAPs; Neddylation; KEAP1-NFE2L2 pathway; RHOBTB3 ATPase cycle; RHOBTB2 GTPase cycle; RHOBTB1 GTPase cycle"	"15"	"0"	"236.7"	"200.7"	"346.2"	"317.7"	"233.8"	"234.9"	"538.4"	"604.3"	"926.3"	"1712.3"	"2020.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22059"	"Oxysterol-binding protein 1 OS=Homo sapiens OX=9606 GN=OSBP PE=1 SV=1"	"0.000"	""	"4"	"3"	"4"	"3"	"807"	"89.4"	"7.30"	"349.86"	"9.98"	"1"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"5007"	"ENSG00000110048"	"OSBP"	"hsa:5007; P22059; Q6P524"	""	"Sphingolipid de novo biosynthesis; Synthesis of bile acids and bile salts"	"2"	"0"	"65.7"	"44.8"	"67.4"	"79.7"	"52.5"	"52.0"	"115.6"	"130.6"	"188.3"	"864.0"	"1562.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C6"	"Peptidyl-prolyl cis-trans isomerase-like 1 OS=Homo sapiens OX=9606 GN=PPIL1 PE=1 SV=1"	"0.000"	""	"23"	"3"	"6"	"3"	"166"	"18.2"	"7.99"	"1373.33"	"9.98"	"3"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus"	"other molecular function"	"Pf00160"	"51645"	"ENSG00000137168"	"PPIL1"	"hsa:51645; O15001; Q5TDC9; Q9Y3C6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"215.5"	"200.0"	"254.9"	"325.7"	"196.5"	"206.8"	"357.9"	"353.5"	"466.0"	"927.0"	"1369.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43487"	"Ran-specific GTPase-activating protein OS=Homo sapiens OX=9606 GN=RANBP1 PE=1 SV=1"	"0.000"	""	"17"	"2"	"3"	"2"	"201"	"23.3"	"5.29"	"269.53"	"9.97"	"1"	"2"	"transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00638"	"5902"	"ENSG00000099901"	"RANBP1"	"hsa:5902; P43487; Q53EY3"	"22q11.2 copy number variation syndrome"	"Rev-mediated nuclear export of HIV RNA"	"2"	"0"	"70.1"	"63.6"	"99.2"	"142.1"	"63.0"	"64.4"	"120.1"	"130.3"	"201.1"	"410.1"	"775.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12004"	"Proliferating cell nuclear antigen OS=Homo sapiens OX=9606 GN=PCNA PE=1 SV=1"	"0.000"	""	"15"	"4"	"7"	"4"	"261"	"28.8"	"4.69"	"1244.74"	"9.96"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00705, Pf02747"	"5111"	"ENSG00000132646"	"PCNA"	"B2R897; D3DW02; hsa:5111; P12004"	"Cell cycle; Retinoblastoma gene in cancer; Primary focal segmental glomerulosclerosis (FSGS); Oxidative damage response; EGF/EGFR signaling pathway; G1 to S cell cycle control; DNA replication; Hepatitis B infection; Base excision repair; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; 16p11.2 proximal deletion syndrome; p53 transcriptional gene network; Nucleotide excision repair in xeroderma pigmentosum ; Urotensin-II-mediated signaling pathway; DNA mismatch repair; 10q11.21q11.23 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling"	"E3 ubiquitin ligases ubiquitinate target proteins; SUMOylation of DNA replication proteins; Termination of translesion DNA synthesis; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; G1/S-Specific Transcription; Recognition of DNA damage by PCNA-containing replication complex; Transcription of E2F targets under negative control by DREAM complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"45"	"0"	"292.5"	"313.2"	"312.2"	"519.0"	"255.5"	"260.3"	"474.2"	"885.7"	"589.8"	"1629.5"	"1282.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15057"	"Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ACAP2 PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"778"	"88.0"	"6.80"	"754.25"	"9.96"	"2"	"3"	"transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412, Pf12796, Pf16746"	"23527"	"ENSG00000114331"	"ACAP2"	"A8K2V4; hsa:23527; Q15057; Q8N5Z8; Q9UQR3"	""	""	"0"	"0"	"199.3"	"137.5"	"278.0"	"248.9"	"207.6"	"204.9"	"424.7"	"433.9"	"560.5"	"1084.5"	"1611.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51003"	"Poly(A) polymerase alpha OS=Homo sapiens OX=9606 GN=PAPOLA PE=1 SV=4"	"0.000"	""	"6"	"4"	"5"	"4"	"745"	"82.8"	"7.37"	"500.78"	"9.93"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"10914"	"ENSG00000090060"	"PAPOLA"	"hsa:10914; P51003; Q86SX4; Q86TV0; Q8IYF5; Q9BVU2"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; Processing of Intronless Pre-mRNAs"	"5"	"0"	"74.9"	"59.1"	"100.8"	"117.7"	"80.5"	"78.1"	"262.5"	"277.6"	"502.6"	"1645.2"	"2211.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62906"	"60S ribosomal protein L10a OS=Homo sapiens OX=9606 GN=RPL10A PE=1 SV=2"	"0.000"	""	"21"	"4"	"8"	"4"	"217"	"24.8"	"9.94"	"2185.70"	"9.92"	"4"	"3"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf00687"	"4736"	"ENSG00000198755"	"RPL10A"	"B2R801; hsa:4736; P52859; P53025; P62906; Q5TZT6; Q8J013"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"311.4"	"334.2"	"441.0"	"649.0"	"321.1"	"319.9"	"633.9"	"663.4"	"856.4"	"2124.6"	"3386.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12923"	"Tyrosine-protein phosphatase non-receptor type 13 OS=Homo sapiens OX=9606 GN=PTPN13 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"2485"	"276.7"	"6.42"	"906.22"	"9.92"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00102, Pf00373, Pf00595, Pf09379, Pf09380, Pf16599"	"5783"	"ENSG00000163629"	"PTPN13"	"B2RTR0; hsa:5783; Q12923; Q15159; Q15263; Q15264; Q15265; Q15674; Q16826; Q8IWH7; Q9NYN9; Q9UDA8"	"Apoptosis modulation and signaling; Ectoderm differentiation; Ectoderm differentiation"	"RND2 GTPase cycle; Synthesis of PIPs at the plasma membrane; RND3 GTPase cycle; RND1 GTPase cycle; Interleukin-37 signaling"	"8"	"0"	"47.5"	"40.9"	"46.6"	"64.8"	"37.8"	"34.8"	"78.2"	"84.4"	"114.8"	"256.6"	"338.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3P2"	"Negative elongation factor A OS=Homo sapiens OX=9606 GN=NELFA PE=1 SV=3"	"0.000"	""	"4"	"2"	"6"	"2"	"528"	"57.2"	"9.03"	"1312.10"	"9.90"	"2"	"2"	"other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"7469"	"ENSG00000185049"	"NELFA"	"A2A2T1; hsa:7469; O95392; Q9H3P2"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	"115.5"	"119.8"	"146.0"	"148.1"	"112.5"	"97.1"	"182.5"	"179.3"	"208.9"	"407.1"	"472.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQ50"	"39S ribosomal protein L40, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL40 PE=1 SV=1"	"0.000"	""	"16"	"2"	"4"	"2"	"206"	"24.5"	"9.63"	"1113.76"	"9.88"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf09812"	"64976"	"ENSG00000185608"	"MRPL40"	"B3KVZ7; hsa:64976; O95134; Q9NQ50"	"22q11.2 copy number variation syndrome"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"67.7"	"55.7"	"83.5"	"103.6"	"69.8"	"64.2"	"106.4"	"88.4"	"112.3"	"179.9"	"231.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99569"	"Plakophilin-4 OS=Homo sapiens OX=9606 GN=PKP4 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1192"	"131.8"	"8.94"	"700.61"	"9.88"	"2"	"3"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"8502"	"ENSG00000144283"	"PKP4"	"hsa:8502; Q86W91; Q99569"	""	"Formation of the cornified envelope; RND2 GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"5"	"0"	"105.6"	"95.0"	"138.0"	"158.2"	"114.0"	"90.8"	"175.9"	"196.1"	"246.2"	"555.8"	"904.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y295"	"Developmentally-regulated GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=DRG1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"6"	"3"	"367"	"40.5"	"8.90"	"1004.18"	"9.85"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"4733"	"ENSG00000185721"	"DRG1"	"B2RDS8; hsa:4733; Q6FGP8; Q8WW69; Q9UGF2; Q9Y295"	""	""	"0"	"0"	"159.1"	"159.8"	"185.2"	"207.0"	"155.2"	"171.1"	"250.6"	"274.1"	"312.5"	"772.4"	"831.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21796"	"Voltage-dependent anion-selective channel protein 1 OS=Homo sapiens OX=9606 GN=VDAC1 PE=1 SV=2"	"0.000"	""	"12"	"3"	"5"	"2"	"283"	"30.8"	"8.54"	"816.19"	"9.85"	"2"	"3"	"cell-cell signaling;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"transporter activity;other molecular function"	"Pf01459"	"7416"	"ENSG00000213585"	"VDAC1"	"B3KVK4; D3DQ93; hsa:7416; P21796; Q5FVE7; Q9UIQ5; Q9UPL0"	"Alzheimer's disease and miRNA effects; Alzheimer's disease; Arsenic metabolism and reactive oxygen species generation; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes"	"Ub-specific processing proteases; Pyruvate metabolism; Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy; Mitochondrial calcium ion transport"	"10"	"1"	"54.5"	"57.0"	"93.2"	"113.3"	"36.7"	"51.4"	"139.8"	"147.6"	"264.8"	"683.3"	"935.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14699"	"Raftlin OS=Homo sapiens OX=9606 GN=RFTN1 PE=1 SV=4"	"0.000"	""	"7"	"3"	"6"	"3"	"578"	"63.1"	"5.67"	"1163.35"	"9.83"	"3"	"3"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity"	"Pf15250"	"23180"	"ENSG00000131378"	"RFTN1"	"hsa:23180; Q0D2G0; Q14699; Q496Y2; Q4QQI7; Q5JB48; Q7Z7P2"	""	""	"0"	"0"	"68.8"	"47.3"	"94.7"	"101.8"	"67.4"	"60.3"	"142.3"	"154.2"	"274.7"	"657.1"	"976.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q49A26"	"Putative oxidoreductase GLYR1 OS=Homo sapiens OX=9606 GN=GLYR1 PE=1 SV=4"	"0.000"	""	"5"	"2"	"4"	"2"	"553"	"60.5"	"9.17"	"795.37"	"9.83"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf03446, Pf14833"	"84656"	"ENSG00000140632"	"GLYR1"	"B4DL47; C9JJ40; C9JJ60; hsa:84656; Q49A26; Q5U632; Q6P1Q2; Q6V3W7; Q9BTI1; Q9BXK2"	""	""	"0"	"0"	"13.7"	"11.2"	"17.6"	"16.3"	"17.8"	"16.5"	"22.2"	"32.1"	"39.0"	"118.1"	"141.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TU7"	"Actin-histidine N-methyltransferase OS=Homo sapiens OX=9606 GN=SETD3 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"594"	"67.2"	"5.96"	"828.38"	"9.82"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00856, Pf09273"	"84193"	"ENSG00000183576"	"SETD3"	"A0PJU3; A5PLP0; B4DZE8; hsa:84193; Q0VAQ2; Q659C0; Q86TU7; Q86TU8; Q96GY9; Q9H5U5"	"Histone modifications"	"PKMTs methylate histone lysines"	"2"	"0"	"53.5"	"62.3"	"54.7"	"73.3"	"54.8"	"55.2"	"174.5"	"190.7"	"341.5"	"933.1"	"1003.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H5V9"	"UPF0428 protein CXorf56 OS=Homo sapiens OX=9606 GN=CXorf56 PE=1 SV=1"	"0.000"	""	"17"	"4"	"6"	"4"	"222"	"25.6"	"8.73"	"1043.06"	"9.79"	"3"	"3"	"cell organization and biogenesis;transport"	"cytoskeleton;nucleus;other cell component"	""	""	"63932"	"ENSG00000018610"	"STEEP1"	"A8MPX7; B4DQN2; D3DWH9; F5GWL7; hsa:63932; O43351; Q9H5V9"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"660.7"	"463.6"	"660.7"	"740.6"	"578.5"	"585.5"	"810.5"	"819.4"	"973.5"	"1664.5"	"1853.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07951"	"Tropomyosin beta chain OS=Homo sapiens OX=9606 GN=TPM2 PE=1 SV=1"	"0.000"	""	"16"	"4"	"7"	"1"	"284"	"32.8"	"4.70"	"1775.81"	"9.78"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7169"	"ENSG00000198467"	"TPM2"	"A6NM85; hsa:7169; P06468; P07951; Q13894; Q53FM4; Q5TCU4; Q5TCU7; Q9UH67"	"Striated muscle contraction pathway; 5q35 copy number variation"	"Smooth Muscle Contraction; Striated Muscle Contraction"	"4"	"3"	"314.0"	"259.0"	"425.3"	"591.4"	"263.9"	"250.0"	"409.7"	"421.0"	"572.9"	"1232.7"	"1655.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWM7"	"Ataxin-2-like protein OS=Homo sapiens OX=9606 GN=ATXN2L PE=1 SV=2"	"0.000"	""	"4"	"3"	"6"	"3"	"1075"	"113.3"	"8.59"	"1248.05"	"9.77"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"11273"	"ENSG00000168488"	"ATXN2L"	"A8K1R6; B9EGM2; E9PAR9; hsa:11273; O95135; Q63ZY4; Q6NVJ8; Q6PJW6; Q8IU61; Q8IU95; Q8WWM3; Q8WWM4; Q8WWM5; Q8WWM6; Q8WWM7; Q99703"	"16p11.2 distal deletion syndrome"	""	"1"	"0"	"341.9"	"278.8"	"349.4"	"391.2"	"318.8"	"338.9"	"438.0"	"468.1"	"540.1"	"1106.6"	"1628.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16891"	"MICOS complex subunit MIC60 OS=Homo sapiens OX=9606 GN=IMMT PE=1 SV=1"	"0.000"	""	"5"	"4"	"7"	"4"	"758"	"83.6"	"6.48"	"1410.95"	"9.72"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf09731"	"10989"	"ENSG00000132305"	"IMMT"	"B1H0U5; B2R5N6; hsa:10989; Q14539; Q15092; Q16891; Q68D41; Q69HW5; Q6IBL0; Q7Z3X1; Q8TAJ5; Q9P0V2"	""	"Cristae formation"	"1"	"0"	"236.6"	"225.1"	"274.2"	"374.9"	"252.0"	"232.2"	"403.7"	"412.8"	"533.1"	"1547.6"	"2319.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13451"	"Peptidyl-prolyl cis-trans isomerase FKBP5 OS=Homo sapiens OX=9606 GN=FKBP5 PE=1 SV=2"	"0.000"	""	"9"	"2"	"3"	"2"	"457"	"51.2"	"5.90"	"450.00"	"9.63"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00254, Pf00515"	"2289"	"ENSG00000096060"	"FKBP5"	"F5H7R1; hsa:2289; Q13451; Q59EB8; Q5TGM6"	"Androgen receptor network in prostate cancer; Farnesoid X receptor pathway; Nuclear receptors meta-pathway; MECP2 and associated Rett syndrome"	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; ESR-mediated signaling; MECP2 regulates neuronal receptors and channels"	"7"	"0"	"24.4"	"33.5"	"37.0"	"48.8"	"35.9"	"33.1"	"50.6"	"59.7"	"81.8"	"262.3"	"558.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99497"	"Parkinson disease protein 7 OS=Homo sapiens OX=9606 GN=PARK7 PE=1 SV=2"	"0.000"	""	"18"	"3"	"6"	"3"	"189"	"19.9"	"6.79"	"1093.03"	"9.61"	"3"	"2"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01965"	"11315"	"ENSG00000116288"	"PARK7"	"B2R4Z1; hsa:11315; O14805; Q6DR95; Q7LFU2; Q99497"	"Androgen receptor signaling pathway; Synaptic vesicle pathway; Parkinson's disease pathway"	"Late endosomal microautophagy; Aggrephagy; SUMOylation of transcription cofactors; Chaperone Mediated Autophagy"	"7"	"0"	"437.0"	"380.1"	"457.3"	"581.7"	"344.1"	"335.1"	"491.6"	"535.2"	"553.0"	"843.5"	"1103.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UG63"	"ATP-binding cassette sub-family F member 2 OS=Homo sapiens OX=9606 GN=ABCF2 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"623"	"71.2"	"7.37"	"1103.64"	"9.60"	"3"	"3"	""	""	"other molecular function"	"Pf00005, Pf12848"	"10061; 114483834"	"ENSG00000033050"	"ABCF2"	"hsa:10061; hsa:114483834; O60864; Q75MJ0; Q75MJ1; Q96TE8; Q9UG63"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"46.0"	"57.8"	"69.9"	"82.6"	"59.4"	"63.5"	"80.9"	"82.4"	"98.5"	"133.7"	"145.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13409"	"Cytoplasmic dynein 1 intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1I2 PE=1 SV=3"	"0.000"	""	"6"	"3"	"6"	"3"	"638"	"71.4"	"5.20"	"1067.58"	"9.59"	"3"	"3"	"transport;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf11540"	"1781"	"ENSG00000077380"	"DYNC1I2"	"B7ZA04; D3DPD4; D3DPD5; D3DPD6; hsa:1781; Q13409; Q32LY9; Q53S84; Q5BJF8; Q7Z4X1; Q96NG7; Q96S87; Q9BXZ5; Q9NT58"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"MHC class II antigen presentation; Separation of Sister Chromatids; Aggrephagy; Regulation of PLK1 Activity at G2/M Transition; RHO GTPases Activate Formins; COPI-mediated anterograde transport; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; EML4 and NUDC in mitotic spindle formation; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"21"	"0"	"211.6"	"198.4"	"225.2"	"254.1"	"186.1"	"209.1"	"271.1"	"272.8"	"344.5"	"903.8"	"1408.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW92"	"Threonine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=TARS2 PE=1 SV=1"	"0.000"	""	"6"	"4"	"7"	"4"	"718"	"81.0"	"7.30"	"1327.28"	"9.57"	"4"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00587, Pf02824, Pf03129, Pf07973"	"80222"	"ENSG00000143374"	"TARS2"	"hsa:80222; Q53GW7; Q96I50; Q9BW92; Q9H9V2"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"178.6"	"145.2"	"214.1"	"242.6"	"179.5"	"181.7"	"398.7"	"442.0"	"717.5"	"1817.3"	"2271.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y605"	"MORF4 family-associated protein 1 OS=Homo sapiens OX=9606 GN=MRFAP1 PE=1 SV=1"	"0.000"	""	"17"	"2"	"6"	"2"	"127"	"14.6"	"4.70"	"1002.85"	"9.57"	"2"	"2"	""	"nucleus;other cell component"	""	"Pf15155"	"93621"	"ENSG00000179010"	"MRFAP1"	"B3KVT2; D3DVT3; hsa:93621; Q9Y605"	""	""	"0"	"0"	"200.3"	"195.7"	"226.2"	"258.3"	"197.8"	"190.9"	"282.2"	"307.9"	"333.5"	"563.3"	"646.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P41240"	"Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1"	""	""	"8"	"3"	"3"	"3"	"450"	"50.7"	"7.06"	""	"9.57"	""	"3"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"1445"	"ENSG00000103653"	"CSK"	"hsa:1445; P41240; Q2M3N2; Q6FGZ6"	"Integrin-mediated cell adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Regulation of actin cytoskeleton"	"Negative regulation of FLT3; Phosphorylation of CD3 and TCR zeta chains; PD-1 signaling; Signaling by BRAF and RAF1 fusions; GAB1 signalosome; Integrin signaling; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; RHOH GTPase cycle; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"18"	"0"	"70.0"	"67.4"	"62.9"	"87.5"	"56.3"	"60.1"	"127.5"	"132.6"	"175.8"	"822.6"	"1615.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZN8"	"UPF0687 protein C20orf27 OS=Homo sapiens OX=9606 GN=C20orf27 PE=1 SV=3"	"0.000"	""	"20"	"2"	"3"	"2"	"174"	"19.3"	"6.84"	"352.74"	"9.56"	"1"	"2"	"other metabolic processes;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf15006"	"54976"	"ENSG00000101220"	"ADISSP"	"A8K4J0; D3DVX8; hsa:54976; Q5JX81; Q9GZN8; Q9NWX3"	""	""	"0"	"0"	"46.1"	"45.9"	"46.0"	"74.8"	"45.6"	"55.9"	"132.5"	"161.1"	"245.6"	"665.0"	"878.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14166"	"Tubulin--tyrosine ligase-like protein 12 OS=Homo sapiens OX=9606 GN=TTLL12 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"644"	"74.4"	"5.53"	"412.03"	"9.54"	"1"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03133"	"23170"	"ENSG00000100304"	"TTLL12"	"hsa:23170; Q14166; Q20WK5; Q9UGU3"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"134.5"	"126.2"	"157.7"	"181.8"	"136.9"	"141.9"	"208.3"	"207.4"	"247.6"	"447.3"	"672.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61586"	"Transforming protein RhoA OS=Homo sapiens OX=9606 GN=RHOA PE=1 SV=1"	"0.000"	""	"14"	"2"	"4"	"2"	"193"	"21.8"	"6.10"	"865.94"	"9.52"	"2"	"2"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"387"	"ENSG00000067560"	"RHOA"	"hsa:387; P06749; P61586; Q53HM4; Q5U024; Q9UDJ0; Q9UEJ4"	"Androgen receptor signaling pathway; Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Leptin signaling pathway; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; Focal adhesion; G protein signaling pathways; Wnt signaling pathway; Hypothetical craniofacial development pathway; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Fibrin complement receptor 3 signaling pathway; Wnt signaling in kidney disease; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; Wnt signaling; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Leukocyte-intrinsic Hippo pathway functions; Neural crest cell migration during development; Neural crest cell migration in cancer; Joubert syndrome; Gastrin signaling pathway; Netrin-UNC5B signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; PtdIns(4,5)P2 in cytokinesis pathway; 2q11.2 copy number variation syndrome; 2q21.1 copy number variation syndrome; G13 signaling pathway; 13q12.12 copy number variation; DNA damage response (only ATM dependent); Serotonin HTR1 group and FOS pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; G alpha (12/13) signalling events; RHO GTPases Activate Formins; Neutrophil degranulation; EPHB-mediated forward signaling; GPVI-mediated activation cascade; PI3K/AKT activation; VEGFA-VEGFR2 Pathway; ERBB2 Regulates Cell Motility; RHO GTPases activate CIT; G beta:gamma signalling through PI3Kgamma; PCP/CE pathway; RHO GTPases Activate Rhotekin and Rhophilins; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; Sema4D mediated inhibition of cell attachment and migration; Ovarian tumor domain proteases; SLIT2:ROBO1 increases RHOA activity; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition); Axonal growth stimulation; Axonal growth inhibition (RHOA activation); RHO GTPases activate KTN1"	"70"	"0"	"98.4"	"57.1"	"140.8"	"147.7"	"97.7"	"87.7"	"160.2"	"154.1"	"215.2"	"373.3"	"559.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95239"	"Chromosome-associated kinesin KIF4A OS=Homo sapiens OX=9606 GN=KIF4A PE=1 SV=3"	"0.000"	""	"3"	"3"	"6"	"3"	"1232"	"139.8"	"6.27"	"954.01"	"9.52"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225"	"24137"	"ENSG00000090889"	"KIF4A"	"B2R7V5; D3DVU4; hsa:24137; O95239; Q86TN3; Q86XX7; Q9NNY6; Q9NY24; Q9UMW3"	"Retinoblastoma gene in cancer"	"Recycling pathway of L1; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"5"	"0"	"118.0"	"110.7"	"123.5"	"136.0"	"124.1"	"109.0"	"214.9"	"219.4"	"333.8"	"768.7"	"1059.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX55"	"Huntingtin-interacting protein K OS=Homo sapiens OX=9606 GN=HYPK PE=1 SV=2"	"0.000"	""	"26"	"3"	"6"	"3"	"129"	"14.7"	"4.93"	"1988.57"	"9.50"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf04419, Pf19026"	"100137436; 101127706; 104002286; 104679625; 105491324; 105549422; 105588143; 108521295; 25764; 713266"	"ENSCATG00000038565; ENSGGOG00000014809; ENSMFAG00000057677; ENSMLEG00000000898; ENSMMUG00000022768; ENSMNEG00000018318; ENSPANG00000018102; ENSPPAG00000034659; ENSPTEG00000009792; ENSPTEG00000019135; ENSPTRG00000038721; ENSRBIG00000028237; ENSRROG00000039445; ENSTGEG00000007663"	"HYPK; LOC113219833"	"A0A024R5Q1; A0A1D5R5K3; A0A2I2YQJ1; A0A2J8NTT0; A0A2K5N035; A0A2K5TR12; A0A2K5XAQ0; A0A2K6AXP0; A0A2K6KBN5; A0A2K6QRU2; A0A2R9B6N1; A0A663DGD1; A0A6D2Y1W8; A0A8C9GZF6; A0A8D2ERJ4; A0A8J8XMG0; A9X1C4; F7GC11; G7MX15; G7PB77; H2Q9B3; hsa:25764; mcc:713266; mleu:105549422; mni:105491324; panu:100137436; ptr:104002286; rbb:108521295; rro:104679625"	""	""	"0"	"0"	"38.2"	"34.8"	"46.2"	"70.6"	"28.7"	"32.4"	"162.2"	"158.9"	"279.9"	"1514.7"	"1959.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y4Y9"	"U6 snRNA-associated Sm-like protein LSm5 OS=Homo sapiens OX=9606 GN=LSM5 PE=1 SV=3"	""	""	"30"	"2"	"3"	"2"	"91"	"9.9"	"4.54"	""	"9.48"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"23658"	"ENSG00000106355"	"LSM5"	"hsa:23658; Q9Y4Y9"	""	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"2"	"0"	"10.0"	"3.9"	"9.1"	"13.2"	"7.2"	"9.1"	"14.6"	"18.2"	"17.0"	"48.4"	"84.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62306"	"Small nuclear ribonucleoprotein F OS=Homo sapiens OX=9606 GN=SNRPF PE=1 SV=1"	"0.000"	""	"15"	"1"	"6"	"1"	"86"	"9.7"	"4.67"	"1236.50"	"9.47"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"6636"	"ENSG00000139343"	"SNRPF"	"A2VCR2; B2R498; hsa:6636; P62306; Q15356; Q6IBQ1; Q6P4I0"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway; RNA Polymerase II Transcription Termination; snRNP Assembly; SARS-CoV-2 modulates host translation machinery; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"8"	"0"	"32.5"	"28.9"	"41.5"	"47.8"	"33.7"	"26.1"	"38.2"	"49.9"	"54.0"	"145.3"	"227.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IUF8"	"Ribosomal oxygenase 2 OS=Homo sapiens OX=9606 GN=RIOX2 PE=1 SV=1"	""	""	"6"	"1"	"2"	"1"	"465"	"52.8"	"6.70"	""	"9.46"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08007, Pf20514"	"84864"	"ENSG00000170854"	"RIOX2"	"D3DN35; hsa:84864; Q6AHW4; Q6SKS0; Q8IU69; Q8IUF6; Q8IUF7; Q8IUF8; Q96C17; Q96KB0"	""	"HDMs demethylate histones"	"1"	"0"	"12.3"	"3.4"	"7.5"	"17.8"	"6.7"	"3.9"	"14.3"	"20.0"	"28.7"	"99.3"	"74.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14240"	"Eukaryotic initiation factor 4A-II OS=Homo sapiens OX=9606 GN=EIF4A2 PE=1 SV=2"	"0.000"	""	"10"	"3"	"6"	"1"	"407"	"46.4"	"5.48"	"1054.69"	"9.45"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1974"	"ENSG00000156976"	"EIF4A2"	"D3DNU9; hsa:1974; Q14240; Q53XJ6; Q96B90; Q96EA8"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"Deadenylation of mRNA; ISG15 antiviral mechanism; L13a-mediated translational silencing of Ceruloplasmin expression; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Ribosomal scanning and start codon recognition"	"9"	"2"	"127.6"	"118.1"	"157.7"	"191.5"	"119.2"	"107.5"	"181.6"	"187.0"	"206.0"	"452.5"	"817.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDP1"	"Ribonuclease H2 subunit C OS=Homo sapiens OX=9606 GN=RNASEH2C PE=1 SV=1"	"0.000"	""	"20"	"3"	"4"	"3"	"164"	"17.8"	"5.03"	"421.46"	"9.43"	"1"	"3"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	""	"Pf08615"	"84153"	"ENSG00000172922"	"RNASEH2C"	"hsa:84153; Q8TDP1; Q9H7F5"	""	""	"0"	"0"	"191.4"	"160.9"	"189.5"	"236.3"	"176.4"	"183.0"	"441.3"	"460.5"	"740.4"	"1826.1"	"2336.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EI5"	"Transcription elongation factor A protein-like 4 OS=Homo sapiens OX=9606 GN=TCEAL4 PE=1 SV=2"	"0.000"	""	"15"	"3"	"6"	"3"	"215"	"24.6"	"5.20"	"930.62"	"9.41"	"3"	"3"	""	"nucleus"	""	"Pf04538"	"79921"	"ENSG00000133142"	"TCEAL4"	"hsa:79921; Q8WY12; Q96EI5; Q9H2H1; Q9H775"	""	""	"0"	"0"	"207.2"	"213.8"	"245.0"	"299.0"	"223.4"	"214.5"	"339.1"	"377.7"	"471.3"	"707.2"	"756.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4V328"	"GRIP1-associated protein 1 OS=Homo sapiens OX=9606 GN=GRIPAP1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"841"	"95.9"	"5.11"	"673.94"	"9.41"	"2"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	""	"56850"	"ENSG00000068400"	"GRIPAP1"	"A6NL78; hsa:56850; Q3MJ75; Q4V327; Q4V328; Q4V330; Q5HYG1; Q6N046; Q96DH8; Q9NQ43; Q9ULQ3"	""	""	"0"	"0"	"12.9"	"13.7"	"22.8"	"25.7"	"16.7"	"19.0"	"39.5"	"39.9"	"80.5"	"208.7"	"287.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T5C0"	"Syntaxin-binding protein 5 OS=Homo sapiens OX=9606 GN=STXBP5 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"1151"	"127.5"	"7.28"	"302.92"	"9.41"	"1"	"2"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00400, Pf08366, Pf08596"	"134957"	"ENSG00000164506"	"STXBP5"	"hsa:134957; Q14DF3; Q5T5C0; Q5T5C1; Q5T5C2; Q8NBG8; Q96NG9"	""	""	"0"	"0"	"7.7"	"16.7"	"15.8"	"20.7"	"7.8"	"17.5"	"58.0"	"59.5"	"113.1"	"361.3"	"592.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62333"	"26S proteasome regulatory subunit 10B OS=Homo sapiens OX=9606 GN=PSMC6 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"389"	"44.1"	"7.49"	"906.03"	"9.41"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5706"	"ENSG00000100519"	"PSMC6"	"B2R975; hsa:5706; P49719; P62333; Q6IBU3; Q92524"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Regulation of expression of SLITs and ROBOs; The role of GTSE1 in G2/M progression after G2 checkpoint; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; SARS-CoV-1 targets host intracellular signalling and regulatory pathways"	"65"	"0"	"99.2"	"94.5"	"141.2"	"177.0"	"103.7"	"116.4"	"194.5"	"178.9"	"228.5"	"506.9"	"1007.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9B1"	"Histone-lysine N-methyltransferase EHMT1 OS=Homo sapiens OX=9606 GN=EHMT1 PE=1 SV=4"	"0.000"	""	"4"	"4"	"6"	"4"	"1298"	"141.4"	"5.76"	"1099.39"	"9.39"	"3"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00856, Pf05033, Pf12796"	"79813"	"ENSG00000181090"	"EHMT1"	"B1AQ58; B1AQ59; hsa:79813; Q86X08; Q8TCN7; Q96F53; Q96JF1; Q96KH4; Q9H9B1"	"Histone modifications; MTHFR deficiency; Kleefstra syndrome"	"PKMTs methylate histone lysines; Senescence-Associated Secretory Phenotype (SASP); Regulation of TP53 Activity through Methylation; Transcriptional Regulation by E2F6; Transcriptional Regulation by VENTX"	"8"	"0"	"241.9"	"232.6"	"249.5"	"265.8"	"207.0"	"200.2"	"302.1"	"303.0"	"336.5"	"687.8"	"1003.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HD33"	"39S ribosomal protein L47, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL47 PE=1 SV=2"	"0.000"	""	"11"	"3"	"6"	"3"	"250"	"29.4"	"10.37"	"901.46"	"9.36"	"3"	"3"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf06984"	"57129"	"ENSG00000136522"	"MRPL47"	"hsa:57129; Q6XRG1; Q8N5D1; Q9HD33"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"68.7"	"75.7"	"77.6"	"109.2"	"68.9"	"61.9"	"130.3"	"145.2"	"177.4"	"484.0"	"866.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBQ5"	"Eukaryotic translation initiation factor 3 subunit K OS=Homo sapiens OX=9606 GN=EIF3K PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"218"	"25.0"	"4.93"	"905.57"	"9.35"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10075"	"27335"	"ENSG00000178982; ENSG00000282986"	"EIF3K"	"A8K0I9; B7ZAM9; hsa:27335; Q96IQ0; Q9UBQ5; Q9Y6D1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"6"	"0"	"57.8"	"73.8"	"68.2"	"92.8"	"56.8"	"51.7"	"140.0"	"133.2"	"216.3"	"674.1"	"1988.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P40429"	"60S ribosomal protein L13a OS=Homo sapiens OX=9606 GN=RPL13A PE=1 SV=2"	"0.000"	""	"14"	"3"	"6"	"3"	"203"	"23.6"	"10.93"	"1044.06"	"9.34"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"23521"	"ENSG00000142541"	"RPL13A"	"A8K505; hsa:23521; P40429"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"15"	"0"	"280.0"	"314.4"	"324.0"	"426.8"	"292.3"	"333.6"	"507.3"	"517.5"	"650.1"	"1238.1"	"1901.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4E1"	"WASH complex subunit 2C OS=Homo sapiens OX=9606 GN=WASHC2C PE=1 SV=4"	"0.000"	""	"3"	"2"	"3"	"2"	"1320"	"144.8"	"4.79"	"322.00"	"9.32"	"1"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"18.4"	"11.6"	"18.4"	"24.4"	"15.8"	"18.6"	"34.1"	"31.2"	"43.4"	"99.7"	"186.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y617"	"Phosphoserine aminotransferase OS=Homo sapiens OX=9606 GN=PSAT1 PE=1 SV=2"	""	""	"15"	"3"	"3"	"3"	"370"	"40.4"	"7.66"	""	"9.31"	""	"3"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00266"	"29968"	"ENSG00000135069"	"PSAT1"	"hsa:29968; Q5T7G5; Q5T7G6; Q96AW2; Q9BQ12; Q9Y617"	"Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Male infertility; Neuroinflammation and glutamatergic signaling; Amino acid metabolism in triple-negative breast cancer cells"	"Serine biosynthesis"	"7"	"0"	"33.7"	"45.6"	"47.1"	"80.5"	"37.1"	"35.1"	"58.1"	"81.7"	"115.4"	"346.3"	"995.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62899"	"60S ribosomal protein L31 OS=Homo sapiens OX=9606 GN=RPL31 PE=1 SV=1"	"0.000"	""	"18"	"2"	"6"	"2"	"125"	"14.5"	"10.54"	"1027.59"	"9.31"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01198"	"6160"	"ENSG00000071082"	"RPL31"	"B7Z4K2; D3DVJ4; hsa:6160; P12947; P62899; Q53SQ5; Q6IRZ0; Q6LBJ6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"183.1"	"180.2"	"219.3"	"268.6"	"160.4"	"176.7"	"303.2"	"312.0"	"381.0"	"801.9"	"1054.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJS0"	"Calcium-binding mitochondrial carrier protein Aralar2 OS=Homo sapiens OX=9606 GN=SLC25A13 PE=1 SV=2"	"0.000"	""	"3"	"1"	"5"	"1"	"675"	"74.1"	"8.62"	"1385.14"	"9.31"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00153"	"10165"	"ENSG00000004864"	"SLC25A13"	"hsa:10165; O14566; O14575; Q546F9; Q9NZW1; Q9UJS0; Q9UNI7"	""	"Gluconeogenesis; Mitochondrial protein import; Aspartate and asparagine metabolism"	"3"	"0"	"70.2"	"94.9"	"60.8"	"84.3"	"65.5"	"68.9"	"110.4"	"122.2"	"155.0"	"338.2"	"418.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15372"	"Eukaryotic translation initiation factor 3 subunit H OS=Homo sapiens OX=9606 GN=EIF3H PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"352"	"39.9"	"6.54"	"885.00"	"9.30"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf19445"	"8667"	"ENSG00000147677"	"EIF3H"	"hsa:8667; O15372"	"Translation factors; VEGFA-VEGFR2 signaling; Measles virus infection; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"10"	"0"	"29.7"	"37.0"	"50.3"	"70.7"	"36.8"	"37.2"	"58.7"	"65.6"	"98.4"	"212.0"	"553.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCN4"	"E3 ubiquitin-protein ligase RNF169 OS=Homo sapiens OX=9606 GN=RNF169 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"708"	"77.1"	"9.10"	"1142.30"	"9.30"	"3"	"3"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13920"	"254225"	"ENSG00000166439"	"RNF169"	"hsa:254225; Q6N015; Q8NCN4"	""	""	"0"	"0"	"157.2"	"146.1"	"160.9"	"183.5"	"131.7"	"143.9"	"204.1"	"217.5"	"253.8"	"522.5"	"570.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50579"	"Methionine aminopeptidase 2 OS=Homo sapiens OX=9606 GN=METAP2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"478"	"52.9"	"5.82"	"892.09"	"9.29"	"2"	"2"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00557"	"10988"	"ENSG00000111142"	"METAP2"	"B2RDI8; B4DUX5; G3XA91; hsa:10988; P50579; Q8NB11"	""	"Inactivation, recovery and regulation of the phototransduction cascade"	"1"	"0"	"50.6"	"29.0"	"50.4"	"58.8"	"42.5"	"48.4"	"118.2"	"141.2"	"295.8"	"546.1"	"472.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09493"	"Tropomyosin alpha-1 chain OS=Homo sapiens OX=9606 GN=TPM1 PE=1 SV=2"	"0.000"	""	"16"	"4"	"7"	"1"	"284"	"32.7"	"4.74"	"1730.29"	"9.28"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00261"	"7168"	"ENSG00000140416"	"TPM1"	"B7Z5T7; D9YZV2; D9YZV3; D9YZV8; hsa:7168; P09493; P09494; P10469; Q6DV89; Q6DV90; Q7Z6L8; Q86W64; Q96IK2; Q9UCI1; Q9UCI2; Q9UCY9; Q9Y427"	"Vitamin D receptor pathway; Striated muscle contraction pathway"	"Smooth Muscle Contraction; Striated Muscle Contraction"	"4"	"0"	"17.1"	"17.1"	"23.6"	"25.7"	"20.6"	"19.0"	"30.6"	"50.6"	"69.3"	"262.3"	"377.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP81"	"Serine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=SARS2 PE=1 SV=1"	"0.000"	""	"8"	"3"	"5"	"3"	"518"	"58.2"	"8.13"	"1253.35"	"9.27"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00587"	"54938"	"ENSG00000104835; ENSG00000283104"	"SARS2"	"A6NHW7; B4DE10; hsa:54938; Q9BVP3; Q9NP81"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"50.7"	"39.9"	"63.7"	"87.9"	"48.5"	"50.0"	"101.5"	"100.8"	"132.2"	"447.6"	"757.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9Q2"	"COP9 signalosome complex subunit 7b OS=Homo sapiens OX=9606 GN=COPS7B PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"264"	"29.6"	"6.15"	"426.55"	"9.25"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"64708"	"ENSG00000144524"	"COPS7B"	"hsa:64708; Q53S22; Q5BJG3; Q9H7V6; Q9H9Q2"	"Ciliary landscape"	"Neddylation; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis"	"5"	"0"	"41.7"	"31.4"	"58.9"	"60.0"	"52.9"	"66.5"	"130.9"	"130.7"	"203.2"	"552.2"	"921.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51572"	"B-cell receptor-associated protein 31 OS=Homo sapiens OX=9606 GN=BCAP31 PE=1 SV=3"	"0.000"	""	"12"	"3"	"6"	"3"	"246"	"28.0"	"8.44"	"1118.46"	"9.25"	"3"	"3"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05529, Pf18035"	"10134"	"ENSG00000185825"	"BCAP31"	"B3KQ79; D3DWV5; hsa:10134; P51572; Q13836; Q96CF0"	""	"Antigen Presentation: Folding, assembly and peptide loading of class I MHC; RHOA GTPase cycle; Apoptotic cleavage of cellular proteins"	"4"	"0"	"111.5"	"127.2"	"130.7"	"164.6"	"122.4"	"145.0"	"198.0"	"218.7"	"288.8"	"581.0"	"735.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9A5"	"CCR4-NOT transcription complex subunit 10 OS=Homo sapiens OX=9606 GN=CNOT10 PE=1 SV=1"	"0.000"	""	"4"	"3"	"6"	"3"	"744"	"82.3"	"7.78"	"951.20"	"9.24"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	""	"25904"	"ENSG00000182973"	"CNOT10"	"B7Z7L1; F8WAF2; hsa:25904; Q9BU30; Q9H5J7; Q9H8X1; Q9H9A5; Q9H9W0; Q9HAH3; Q9UFJ2"	"Ciliary landscape"	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"3"	"0"	"190.7"	"145.8"	"196.3"	"230.4"	"193.9"	"177.8"	"311.5"	"292.5"	"428.0"	"1045.6"	"1388.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99633"	"Pre-mRNA-splicing factor 18 OS=Homo sapiens OX=9606 GN=PRPF18 PE=1 SV=1"	"0.000"	""	"16"	"4"	"6"	"4"	"342"	"39.8"	"8.15"	"1080.53"	"9.23"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf02840, Pf08799"	"8559"	"ENSG00000165630"	"PRPF18"	"hsa:8559; Q5T9P9; Q99633; Q9BUI9"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"223.9"	"184.4"	"253.8"	"339.8"	"214.1"	"237.9"	"510.1"	"581.8"	"659.5"	"767.9"	"712.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NCA5"	"Protein FAM98A OS=Homo sapiens OX=9606 GN=FAM98A PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"1"	"518"	"55.2"	"8.95"	"795.94"	"9.23"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10239"	"25940"	"ENSG00000119812"	"FAM98A"	"B2RNA2; hsa:25940; Q8NCA5; Q9Y3Y6"	""	""	"0"	"1"	"54.3"	"42.9"	"78.7"	"89.8"	"55.5"	"55.2"	"112.9"	"118.4"	"167.1"	"383.2"	"588.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3C1"	"Nucleolar protein 16 OS=Homo sapiens OX=9606 GN=NOP16 PE=1 SV=2"	"0.000"	""	"25"	"3"	"5"	"3"	"178"	"21.2"	"9.94"	"1773.11"	"9.20"	"3"	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf09420"	"51491"	"ENSG00000048162"	"NOP16"	"B4DV13; D6RGD3; hsa:51491; Q05D05; Q6IAI6; Q6PIM0; Q8IXL5; Q9Y3C1"	"5q35 copy number variation"	""	"1"	"0"	"159.9"	"155.3"	"164.3"	"199.1"	"160.1"	"148.5"	"243.5"	"240.3"	"299.5"	"536.5"	"717.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y376"	"Calcium-binding protein 39 OS=Homo sapiens OX=9606 GN=CAB39 PE=1 SV=1"	""	""	"9"	"3"	"3"	"3"	"341"	"39.8"	"6.89"	""	"9.19"	""	"3"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf08569"	"51719"	"ENSG00000135932"	"CAB39"	"A8K8L7; hsa:51719; Q9Y376"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endochondral ossification; Endochondral ossification with skeletal dysplasias"	"Neutrophil degranulation; Energy dependent regulation of mTOR by LKB1-AMPK"	"6"	"0"	"31.2"	"30.6"	"43.1"	"61.0"	"28.8"	"39.8"	"117.3"	"127.1"	"176.8"	"656.6"	"1229.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42356"	"Phosphatidylinositol 4-kinase alpha OS=Homo sapiens OX=9606 GN=PI4KA PE=1 SV=4"	"0.000"	""	"2"	"2"	"3"	"2"	"2102"	"236.7"	"7.06"	"440.37"	"9.19"	"1"	"2"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf19274"	"5297"	"ENSG00000241973"	"PI4KA"	"hsa:5297; P42356; Q7Z625; Q9UPG2"	"Ectoderm differentiation; 22q11.2 copy number variation syndrome"	"Synthesis of PIPs at the Golgi membrane; Synthesis of PIPs at the ER membrane"	"4"	"0"	"26.6"	"25.5"	"27.5"	"32.6"	"23.0"	"23.3"	"58.6"	"78.4"	"108.3"	"193.5"	"190.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13098"	"COP9 signalosome complex subunit 1 OS=Homo sapiens OX=9606 GN=GPS1 PE=1 SV=4"	"0.000"	""	"8"	"4"	"6"	"4"	"491"	"55.5"	"6.74"	"1452.00"	"9.19"	"4"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf10602"	"2873"	"ENSG00000169727"	"GPS1"	"hsa:2873; Q13098; Q8NA10; Q9BWL1"	""	"Neddylation; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; RHOBTB1 GTPase cycle; DNA Damage Recognition in GG-NER"	"5"	"0"	"37.0"	"30.3"	"54.7"	"53.8"	"51.0"	"50.6"	"181.2"	"191.9"	"344.4"	"1361.0"	"2301.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48634"	"Protein PRRC2A OS=Homo sapiens OX=9606 GN=PRRC2A PE=1 SV=3"	"0.000"	""	"2"	"3"	"5"	"3"	"2157"	"228.7"	"9.45"	"1638.03"	"9.15"	"3"	"2"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	""	"Pf07001"	"7916"	"ENSG00000204469; ENSG00000206427; ENSG00000225164; ENSG00000225748; ENSG00000226618; ENSG00000231370; ENSG00000231825"	"PRRC2A"	"B0UX77; B0UZE9; B0UZL3; hsa:7916; O95875; P48634; Q05BK4; Q4LE37; Q5SQ29; Q5SQ30; Q5ST84; Q5STX6; Q5STX7; Q68DW9; Q6P9P7; Q6PIN1; Q8MGQ9; Q96QC6"	""	""	"0"	"0"	"386.5"	"363.6"	"374.4"	"496.3"	"368.2"	"376.6"	"478.4"	"526.3"	"555.7"	"856.7"	"1002.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4H7"	"HAUS augmin-like complex subunit 6 OS=Homo sapiens OX=9606 GN=HAUS6 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"955"	"108.6"	"6.47"	"1048.62"	"9.15"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf14661"	"54801"	"ENSG00000147874"	"HAUS6"	"B3KPK4; B4DX82; hsa:54801; Q05CG1; Q14CB6; Q14CD9; Q2TA91; Q6IQ10; Q6NZX5; Q7Z4H7; Q8IZQ4; Q96FN0; Q9H950; Q9H998; Q9HCJ8; Q9NXT8"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"101.3"	"91.4"	"98.9"	"119.0"	"108.2"	"120.3"	"142.4"	"149.5"	"195.1"	"348.2"	"400.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28331"	"NADH-ubiquinone oxidoreductase 75 kDa subunit, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS1 PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"727"	"79.4"	"6.23"	"592.01"	"9.15"	"2"	"3"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00384, Pf09326, Pf10588, Pf13510"	"4719"	"ENSG00000023228; ENSG00000283447"	"NDUFS1"	"B4DIN9; B4DJA0; B4DPG1; B4DUC1; E7ENF3; hsa:4719; P28331; Q53TR8; Q8N1C4; Q8TCC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"104.2"	"72.2"	"109.6"	"134.9"	"89.9"	"95.3"	"224.8"	"200.5"	"338.9"	"936.2"	"1264.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NIZ1"	"Ras-related protein Rap-1b-like protein OS=Homo sapiens OX=9606 PE=2 SV=1"	"0.000"	""	"16"	"2"	"4"	"1"	"184"	"20.9"	"5.48"	"1088.84"	"9.14"	"2"	"2"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf00071"	""	""	"RAP1BL"	"A6NIZ1"	""	""	"0"	"0"	"38.4"	"32.6"	"56.8"	"78.0"	"46.5"	"43.7"	"81.7"	"80.4"	"118.8"	"222.6"	"271.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49207"	"60S ribosomal protein L34 OS=Homo sapiens OX=9606 GN=RPL34 PE=1 SV=3"	"0.000"	""	"21"	"3"	"6"	"3"	"117"	"13.3"	"11.47"	"1063.61"	"9.13"	"3"	"3"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01199"	"6164"	"ENSG00000109475"	"RPL34"	"hsa:6164; P49207; Q6FG66; Q9BUZ2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"196.2"	"301.6"	"218.1"	"280.8"	"223.4"	"190.8"	"370.2"	"388.6"	"476.5"	"985.0"	"1403.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P2E9"	"Enhancer of mRNA-decapping protein 4 OS=Homo sapiens OX=9606 GN=EDC4 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1401"	"151.6"	"5.86"	"965.07"	"9.12"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf16529"	"23644"	"ENSG00000038358"	"EDC4"	"A6NGM1; A8K4T4; hsa:23644; Q13025; Q13826; Q6P2E9; Q6ZR12; Q7Z6H7"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"66.9"	"60.2"	"79.8"	"94.3"	"70.0"	"70.0"	"114.3"	"113.2"	"148.5"	"359.4"	"503.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P206"	"Uncharacterized protein KIAA1522 OS=Homo sapiens OX=9606 GN=KIAA1522 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"1035"	"107.0"	"9.73"	"483.84"	"9.12"	"1"	"2"	"other biological processes"	""	""	""	"57648"	"ENSG00000162522"	"KIAA1522"	"B4DQU8; B5MDY0; C9JH84; hsa:57648; Q8TCQ0; Q9P206"	""	""	"0"	"0"	"11.9"	"9.6"	"11.5"	"19.0"	"18.0"	"13.3"	"18.0"	"22.3"	"30.2"	"91.9"	"116.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T4S7"	"E3 ubiquitin-protein ligase UBR4 OS=Homo sapiens OX=9606 GN=UBR4 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"5183"	"573.5"	"6.04"	"277.05"	"9.11"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02207, Pf13764, Pf19423"	"23352"	"ENSG00000127481"	"UBR4"	"A8MPT2; A8MQ33; A8MQB1; hsa:23352; O60646; O75050; Q4QRK5; Q5T4S7; Q5T4S8; Q5T4S9; Q5TBN8; Q5TBP2; Q6DKH8; Q6P4A4; Q7L8P7; Q8IXJ4; Q8TDN5; Q8WV67; Q9HA46; Q9P2N9; Q9UG82"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neutrophil degranulation"	"2"	"0"	"32.1"	"33.8"	"47.0"	"67.3"	"35.9"	"37.2"	"68.1"	"59.7"	"92.1"	"265.4"	"372.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UXN9"	"WD repeat-containing protein 82 OS=Homo sapiens OX=9606 GN=WDR82 PE=1 SV=1"	"0.000"	""	"12"	"3"	"4"	"3"	"313"	"35.1"	"7.69"	"495.00"	"9.10"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"80335"	"ENSG00000164091"	"WDR82"	"A8K5R5; hsa:80335; Q6UXN9; Q8TEB2"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"213.8"	"155.3"	"201.9"	"245.1"	"175.7"	"214.2"	"288.7"	"293.6"	"384.8"	"954.4"	"1524.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98179"	"RNA-binding protein 3 OS=Homo sapiens OX=9606 GN=RBM3 PE=1 SV=1"	"0.000"	""	"22"	"2"	"4"	"2"	"157"	"17.2"	"8.91"	"760.55"	"9.10"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity"	"Pf00076"	"5935"	"ENSG00000102317"	"RBM3"	"hsa:5935; P98179"	""	""	"0"	"0"	"166.0"	"607.5"	"62.1"	"185.1"	"133.0"	"124.2"	"285.8"	"407.2"	"420.3"	"719.6"	"752.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07237"	"Protein disulfide-isomerase OS=Homo sapiens OX=9606 GN=P4HB PE=1 SV=3"	"0.000"	""	"5"	"3"	"6"	"3"	"508"	"57.1"	"4.87"	"1058.47"	"9.08"	"3"	"3"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00085, Pf13848"	"5034"	"ENSG00000185624"	"P4HB"	"B2RDQ2; hsa:5034; P07237; P30037; P32079; Q15205; Q6LDE5"	"VEGFA-VEGFR2 signaling; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Hedgehog ligand biogenesis; Collagen biosynthesis and modifying enzymes; Detoxification of Reactive Oxygen Species; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Insulin processing; Interleukin-12 signaling; Interleukin-23 signaling; Chylomicron assembly; VLDL assembly; LDL remodeling"	"13"	"0"	"330.1"	"327.9"	"405.2"	"511.3"	"335.4"	"267.6"	"513.3"	"516.5"	"568.4"	"1100.4"	"1371.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14320"	"Protein FAM50A OS=Homo sapiens OX=9606 GN=FAM50A PE=1 SV=2"	"0.000"	""	"9"	"3"	"6"	"3"	"339"	"40.2"	"6.83"	"1043.61"	"9.08"	"3"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf04921"	"9130"	"ENSG00000071859"	"FAM50A"	"A8KAQ4; B2R997; hsa:9130; Q14320; Q5HY37; Q6PJH5"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"118.9"	"110.7"	"133.6"	"154.3"	"98.5"	"114.3"	"263.1"	"269.6"	"490.2"	"1371.5"	"1476.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15785"	"Mitochondrial import receptor subunit TOM34 OS=Homo sapiens OX=9606 GN=TOMM34 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"309"	"34.5"	"8.98"	"892.76"	"9.07"	"2"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00515"	"10953"	"ENSG00000025772"	"TOMM34"	"hsa:10953; Q15785; Q53GH9; Q6IBN7; Q9NTZ3"	""	""	"0"	"0"	"63.9"	"65.6"	"85.7"	"106.3"	"71.8"	"59.2"	"138.1"	"144.5"	"208.5"	"657.5"	"812.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62873"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 OS=Homo sapiens OX=9606 GN=GNB1 PE=1 SV=3"	"0.000"	""	"9"	"2"	"4"	"2"	"340"	"37.4"	"6.00"	"658.03"	"9.06"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2782"	"ENSG00000078369"	"GNB1"	"B1AJZ7; hsa:2782; P04697; P04901; P62873; Q1RMY8"	"Nicotine effect on dopaminergic neurons; Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; 1p36 copy number variation syndrome; Calcium regulation in cardiac cells; Estrogen signaling pathway"	"G alpha (q) signalling events; G alpha (12/13) signalling events; Olfactory Signaling Pathway; G alpha (i) signalling events; G alpha (z) signalling events; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Sensory perception of sweet, bitter, and umami (glutamate) taste; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Inactivation, recovery and regulation of the phototransduction cascade; Glucagon signaling in metabolic regulation; Activation of the phototransduction cascade"	"45"	"0"	"67.6"	"74.9"	"72.3"	"114.2"	"58.8"	"55.2"	"145.3"	"160.8"	"235.7"	"856.3"	"1173.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61962"	"DDB1- and CUL4-associated factor 7 OS=Homo sapiens OX=9606 GN=DCAF7 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"342"	"38.9"	"5.52"	"895.28"	"9.05"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00400"	"10238"	"ENSG00000136485"	"DCAF7"	"B4E039; D3DU14; hsa:10238; O15491; P61962; Q9DAE4"	"Ciliary landscape; DYRK1A involvement regarding cell proliferation in brain development"	"Neddylation; Association of TriC/CCT with target proteins during biosynthesis"	"4"	"0"	"145.6"	"124.5"	"177.8"	"223.0"	"144.2"	"154.9"	"228.1"	"239.4"	"256.4"	"474.8"	"655.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVI1"	"Fanconi anemia group I protein OS=Homo sapiens OX=9606 GN=FANCI PE=1 SV=4"	"0.000"	""	"3"	"3"	"6"	"3"	"1328"	"149.2"	"6.74"	"1107.59"	"9.04"	"3"	"3"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14674, Pf14675, Pf14676, Pf14677, Pf14678, Pf14679, Pf14680"	"55215"	"ENSG00000140525"	"FANCI"	"A4ZVE4; A5YMH4; A6NJZ0; hsa:55215; Q96JN1; Q96ST0; Q9BT96; Q9NVI1"	"Gastric cancer network 2; DNA repair pathways, full network; 15q11q13 copy number variation"	"TP53 Regulates Transcription of DNA Repair Genes; Fanconi Anemia Pathway"	"5"	"0"	"63.7"	"57.2"	"72.5"	"87.4"	"53.3"	"70.9"	"148.2"	"185.3"	"366.7"	"935.7"	"1184.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62851"	"40S ribosomal protein S25 OS=Homo sapiens OX=9606 GN=RPS25 PE=1 SV=1"	"0.000"	""	"22"	"3"	"5"	"3"	"125"	"13.7"	"10.11"	"684.47"	"9.04"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03297"	"6230"	"ENSG00000118181; ENSG00000280831"	"RPS25"	"B2R4M7; hsa:6230; P25111; P62851"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"133.5"	"130.4"	"180.2"	"264.6"	"148.8"	"131.2"	"264.7"	"271.9"	"342.5"	"937.6"	"984.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW08"	"DNA-directed RNA polymerase III subunit RPC2 OS=Homo sapiens OX=9606 GN=POLR3B PE=1 SV=2"	"0.000"	""	"2"	"2"	"5"	"2"	"1133"	"127.7"	"8.50"	"566.98"	"9.04"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00562, Pf04560, Pf04561, Pf04563, Pf04565, Pf04566, Pf04567"	"55703"	"ENSG00000013503"	"POLR3B"	"A8K6H0; B3KV73; F5H1E6; hsa:55703; Q9NW08; Q9NW59"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"10"	"0"	"223.0"	"79.8"	"2559.9"	"144.5"	"37.6"	"158.7"	"496.5"	"265.4"	"203.8"	"234.9"	"392.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVM6"	"DnaJ homolog subfamily C member 17 OS=Homo sapiens OX=9606 GN=DNAJC17 PE=1 SV=1"	"0.000"	""	"18"	"4"	"6"	"4"	"304"	"34.7"	"8.53"	"1862.33"	"9.03"	"4"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf00226"	"55192"	"ENSG00000104129"	"DNAJC17"	"hsa:55192; Q9NVM6"	""	""	"0"	"0"	"40.3"	"32.0"	"44.3"	"61.7"	"31.6"	"45.5"	"135.0"	"155.3"	"283.8"	"1151.0"	"1543.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06210"	"Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 OS=Homo sapiens OX=9606 GN=GFPT1 PE=1 SV=3"	"0.000"	""	"5"	"3"	"6"	"3"	"699"	"78.8"	"7.11"	"1066.23"	"9.01"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01380, Pf13522"	"2673"	"ENSG00000198380"	"GFPT1"	"hsa:2673; Q06210; Q53QE6; Q9BXF8"	"UDP-derived sugars synthesis in fibroblasts"	"XBP1(S) activates chaperone genes; Synthesis of UDP-N-acetyl-glucosamine; Defective GFPT1 causes CMSTA1"	"4"	"0"	"29.2"	"27.6"	"38.3"	"46.4"	"30.6"	"39.5"	"62.4"	"56.7"	"102.6"	"225.3"	"273.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTV0"	"PHD finger-like domain-containing protein 5A OS=Homo sapiens OX=9606 GN=PHF5A PE=1 SV=1"	"0.000"	""	"25"	"3"	"5"	"3"	"110"	"12.4"	"8.41"	"550.51"	"9.00"	"2"	"3"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03660"	"84844"	"ENSG00000100410"	"PHF5A"	"hsa:84844; Q7RTV0; Q9UH06"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"289.4"	"288.0"	"302.4"	"344.9"	"247.3"	"251.9"	"359.1"	"354.5"	"358.4"	"794.2"	"1304.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12792"	"Twinfilin-1 OS=Homo sapiens OX=9606 GN=TWF1 PE=1 SV=3"	"0.000"	""	"8"	"3"	"5"	"2"	"350"	"40.3"	"6.96"	"558.44"	"8.99"	"2"	"3"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00241"	"5756"	"ENSG00000151239"	"TWF1"	"A8K5A8; B3KXS6; B4DLX9; hsa:5756; Q12792; Q59G07; Q5U0B1; Q6FHJ1; Q6FHL6; Q6NUK9; Q86XL6; Q8TCD3"	""	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; RHOBTB2 GTPase cycle"	"3"	"1"	"128.7"	"99.1"	"162.6"	"219.8"	"128.7"	"118.6"	"248.9"	"273.5"	"386.0"	"1615.8"	"2299.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8E8"	"Cysteine-rich protein 2-binding protein OS=Homo sapiens OX=9606 GN=KAT14 PE=1 SV=3"	"0.000"	""	"4"	"2"	"4"	"2"	"782"	"88.8"	"6.57"	"1022.07"	"8.98"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf13673"	"57325"	"ENSG00000149474"	"KAT14"	"A2A2I5; hsa:57325; Q96GW6; Q96IH3; Q9H8E8; Q9HBF0; Q9UIY5"	""	"Formation of WDR5-containing histone-modifying complexes; HATs acetylate histones"	"2"	"0"	"17.1"	"13.3"	"12.9"	"17.6"	"13.4"	"10.4"	"22.8"	"30.3"	"33.0"	"62.0"	"69.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29144"	"Tripeptidyl-peptidase 2 OS=Homo sapiens OX=9606 GN=TPP2 PE=1 SV=4"	"0.000"	""	"3"	"4"	"5"	"4"	"1249"	"138.3"	"6.32"	"643.71"	"8.98"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00082, Pf12580"	"7174"	"ENSG00000134900"	"TPP2"	"hsa:7174; P29144; Q5VZU8"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"65.5"	"60.2"	"63.9"	"96.7"	"64.4"	"55.4"	"111.5"	"118.0"	"165.3"	"497.8"	"895.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20020"	"Plasma membrane calcium-transporting ATPase 1 OS=Homo sapiens OX=9606 GN=ATP2B1 PE=1 SV=4"	"0.000"	""	"3"	"2"	"3"	"2"	"1220"	"134.6"	"5.91"	"522.44"	"8.95"	"1"	"2"	"stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf00702, Pf12424, Pf13246"	"490"	"ENSG00000070961"	"ATP2B1"	"hsa:490; P20020; Q12992; Q12993; Q13819; Q13820; Q13821; Q16504; Q93082"	"Vitamin D receptor pathway; Splicing factor NOVA regulated synaptic proteins; Vitamin D-sensitive calcium signaling in depression; Calcium regulation in cardiac cells"	"Sensory processing of sound by inner hair cells of the cochlea; Ion homeostasis; Ion transport by P-type ATPases; Reduction of cytosolic Ca++ levels"	"8"	"0"	"23.0"	"17.1"	"36.7"	"32.7"	"20.2"	"16.5"	"51.8"	"45.9"	"81.3"	"288.9"	"457.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00487"	"26S proteasome non-ATPase regulatory subunit 14 OS=Homo sapiens OX=9606 GN=PSMD14 PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"2"	"310"	"34.6"	"6.52"	"349.30"	"8.94"	"1"	"2"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01398, Pf13012"	"10213"	"ENSG00000115233"	"PSMD14"	"B3KNW2; hsa:10213; O00176; O00487"	"Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Metalloprotease DUBs"	"64"	"0"	"34.5"	"22.8"	"43.1"	"45.7"	"34.3"	"35.8"	"72.5"	"73.9"	"86.0"	"283.0"	"576.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09417"	"Dihydropteridine reductase OS=Homo sapiens OX=9606 GN=QDPR PE=1 SV=2"	"0.000"	""	"11"	"2"	"3"	"2"	"244"	"25.8"	"7.37"	"472.73"	"8.94"	"1"	"2"	"other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00106"	"5860"	"ENSG00000151552"	"QDPR"	"A8K158; B3KW71; hsa:5860; P09417; Q53F52; Q9H3M5"	""	"Phenylalanine metabolism"	"1"	"0"	"28.8"	"19.6"	"38.5"	"43.9"	"22.9"	"30.9"	"90.3"	"97.4"	"172.3"	"776.2"	"1325.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92738"	"USP6 N-terminal-like protein OS=Homo sapiens OX=9606 GN=USP6NL PE=1 SV=3"	"0.000"	""	"4"	"3"	"6"	"3"	"828"	"94.0"	"9.07"	"1099.43"	"8.94"	"3"	"3"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00566"	"9712"	"ENSG00000148429"	"USP6NL"	"A8KA79; hsa:9712; Q15400; Q5VV10; Q7L0K9; Q92738"	"EGF/EGFR signaling pathway"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	"129.2"	"120.7"	"125.6"	"156.2"	"129.8"	"174.7"	"368.6"	"394.7"	"335.9"	"332.8"	"373.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95433"	"Activator of 90 kDa heat shock protein ATPase homolog 1 OS=Homo sapiens OX=9606 GN=AHSA1 PE=1 SV=1"	"0.000"	""	"10"	"3"	"5"	"3"	"338"	"38.3"	"5.53"	"582.82"	"8.93"	"2"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf08327, Pf09229"	"10598"	"ENSG00000100591"	"AHSA1"	"B2R9L2; B4DUR9; hsa:10598; O95433; Q96IL6; Q9P060"	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	""	"1"	"0"	"33.1"	"30.9"	"39.6"	"50.3"	"32.8"	"34.3"	"60.2"	"57.2"	"87.3"	"200.1"	"388.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46821"	"Microtubule-associated protein 1B OS=Homo sapiens OX=9606 GN=MAP1B PE=1 SV=2"	"0.000"	""	"1"	"3"	"6"	"3"	"2468"	"270.5"	"4.81"	"1081.46"	"8.93"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00414"	"4131"	"ENSG00000131711"	"MAP1B"	"A2BDK5; hsa:4131; P46821"	"Microtubule cytoskeleton regulation; Fragile X syndrome; Neurogenesis regulation in the olfactory epithelium"	""	"3"	"0"	"169.5"	"159.6"	"193.1"	"207.6"	"162.0"	"182.2"	"271.6"	"270.5"	"349.9"	"627.0"	"671.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TZA2"	"Rootletin OS=Homo sapiens OX=9606 GN=CROCC PE=1 SV=1"	"0.000"	""	"2"	"3"	"6"	"2"	"2017"	"228.4"	"5.50"	"1001.55"	"8.92"	"3"	"3"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"56.1"	"43.4"	"54.6"	"88.2"	"43.4"	"43.4"	"73.9"	"79.8"	"94.0"	"163.3"	"251.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HP4"	"Oxidoreductase NAD-binding domain-containing protein 1 OS=Homo sapiens OX=9606 GN=OXNAD1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"4"	"1"	"312"	"34.8"	"8.37"	"941.49"	"8.91"	"1"	"1"	""	""	"other molecular function"	"Pf00175"	"92106"	"ENSG00000154814"	"OXNAD1"	"hsa:92106; Q2HYC7; Q59FA4; Q96HP4"	""	""	"0"	"0"	"22.4"	"22.0"	"24.4"	"31.1"	"24.9"	"26.0"	"66.2"	"91.7"	"121.0"	"249.3"	"263.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26640"	"Valine--tRNA ligase OS=Homo sapiens OX=9606 GN=VARS1 PE=1 SV=4"	"0.000"	""	"3"	"4"	"7"	"4"	"1264"	"140.4"	"7.59"	"1536.42"	"8.89"	"4"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00043, Pf00133, Pf08264"	"7407"	"ENSG00000096171; ENSG00000204394; ENSG00000224264; ENSG00000226589; ENSG00000231116"	"VARS1"	"B0V1N1; B4DZ61; hsa:7407; P26640; Q5JQ90; Q96E77; Q9UQM2"	"Amino acid metabolism"	"Cytosolic tRNA aminoacylation"	"2"	"0"	"329.3"	"281.1"	"335.4"	"344.4"	"280.0"	"309.7"	"383.3"	"389.0"	"403.4"	"628.8"	"788.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB3"	"Serine/arginine repetitive matrix protein 1 OS=Homo sapiens OX=9606 GN=SRRM1 PE=1 SV=2"	"0.000"	""	"6"	"4"	"6"	"4"	"904"	"102.3"	"11.84"	"2188.16"	"8.88"	"4"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf01480"	"10250"	"ENSG00000133226"	"SRRM1"	"hsa:10250; O60585; Q5VVN4; Q8IYB3"	"mRNA processing"	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RHOBTB1 GTPase cycle; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA Splicing - Major Pathway; RHOBTB2 GTPase cycle"	"7"	"0"	"362.3"	"238.6"	"338.7"	"391.7"	"308.2"	"318.4"	"497.8"	"525.4"	"847.6"	"1878.5"	"2441.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15014"	"Mortality factor 4-like protein 2 OS=Homo sapiens OX=9606 GN=MORF4L2 PE=1 SV=1"	"0.000"	""	"10"	"3"	"4"	"3"	"288"	"32.3"	"9.72"	"508.94"	"8.88"	"1"	"3"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf05712"	"9643"	"ENSG00000123562"	"MORF4L2"	"B3KP92; D3DXA5; hsa:9643; Q15014; Q567V0; Q8J026"	""	"HATs acetylate histones"	"1"	"0"	"131.1"	"108.2"	"148.9"	"199.2"	"129.2"	"156.3"	"222.0"	"229.7"	"308.1"	"600.8"	"731.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25440"	"Bromodomain-containing protein 2 OS=Homo sapiens OX=9606 GN=BRD2 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"1"	"801"	"88.0"	"9.09"	"953.25"	"8.86"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf17035"	"6046"	"ENSG00000204256; ENSG00000215077; ENSG00000234507; ENSG00000234704; ENSG00000235307"	"BRD2"	"A2AAU0; B0S7P0; B1AZT1; hsa:6046; O00699; O00700; P25440; Q15310; Q5STC9; Q63HQ9; Q658Y7; Q6P3U2; Q969U4"	""	"RUNX3 regulates p14-ARF"	"1"	"0"	"8.4"	"8.5"	"8.6"	"11.3"	"9.5"	"6.7"	"25.3"	"33.5"	"56.2"	"134.8"	"141.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY89"	"Uncharacterized protein KIAA1671 OS=Homo sapiens OX=9606 GN=KIAA1671 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1806"	"196.6"	"8.47"	"862.75"	"8.85"	"2"	"2"	""	""	""	"Pf15327"	"85379"	"ENSG00000197077"	"KIAA1671"	"B0QYF2; B7ZW08; hsa:85379; Q5THZ5; Q9BY89"	""	""	"0"	"0"	"31.4"	"28.2"	"37.5"	"39.4"	"30.9"	"27.5"	"40.1"	"50.8"	"58.5"	"127.3"	"176.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51970"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 8 OS=Homo sapiens OX=9606 GN=NDUFA8 PE=1 SV=3"	"0.000"	""	"30"	"5"	"9"	"5"	"172"	"20.1"	"7.65"	"2028.17"	"8.84"	"5"	"3"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf06747"	"4702"	"ENSG00000119421"	"NDUFA8"	"B1AM93; hsa:4702; P51970; Q9Y6N0"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"375.6"	"420.8"	"297.4"	"397.3"	"329.7"	"298.6"	"564.7"	"655.1"	"817.9"	"2331.6"	"3148.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4Q2"	"HEAT repeat-containing protein 3 OS=Homo sapiens OX=9606 GN=HEATR3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"6"	"1"	"680"	"74.5"	"5.11"	"1092.39"	"8.84"	"1"	"1"	"transport;other biological processes"	""	"other molecular function"	"Pf13513"	"55027"	"ENSG00000155393"	"HEATR3"	"A8K1N4; hsa:55027; Q7Z4Q2; Q8N525; Q8WV56; Q96CC9; Q9NWN7"	""	""	"0"	"0"	"36.5"	"26.9"	"41.7"	"59.3"	"35.3"	"33.2"	"66.6"	"78.4"	"109.9"	"351.3"	"543.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94913"	"Pre-mRNA cleavage complex 2 protein Pcf11 OS=Homo sapiens OX=9606 GN=PCF11 PE=1 SV=3"	"0.000"	""	"3"	"4"	"7"	"4"	"1555"	"172.9"	"8.48"	"1377.29"	"8.84"	"4"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04818"	"51585"	"ENSG00000165494"	"PCF11"	"A6H8W7; hsa:51585; O43671; O94913; Q6P0X8"	""	"mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RNA polymerase II transcribes snRNA genes; Processing of Intronless Pre-mRNAs"	"5"	"0"	"218.6"	"200.4"	"252.4"	"324.6"	"206.5"	"228.0"	"325.9"	"346.7"	"425.8"	"984.1"	"1714.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14739"	"Delta(14)-sterol reductase LBR OS=Homo sapiens OX=9606 GN=LBR PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"3"	"615"	"70.7"	"9.36"	"1076.49"	"8.83"	"3"	"3"	"other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01222, Pf09465"	"3930"	"ENSG00000143815"	"LBR"	"B2R5P3; hsa:3930; Q14739; Q14740; Q53GU7; Q59FE6"	"Gastric cancer network 2; ATM signaling in development and disease ; Envelope proteins and their potential roles in EDMD physiopathology; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol biosynthesis with skeletal dysplasias; Cholesterol synthesis disorders; Cholesterol metabolism; Enterocyte cholesterol metabolism"	"Regulation of MECP2 expression and activity; Initiation of Nuclear Envelope (NE) Reformation; RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; Cholesterol biosynthesis"	"19"	"0"	"253.2"	"214.5"	"290.2"	"330.4"	"240.6"	"259.4"	"410.5"	"443.3"	"578.2"	"1364.2"	"1705.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVX2"	"Notchless protein homolog 1 OS=Homo sapiens OX=9606 GN=NLE1 PE=1 SV=4"	"0.000"	""	"7"	"2"	"3"	"2"	"485"	"53.3"	"7.34"	"322.65"	"8.83"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus"	""	"Pf00400, Pf08154"	"54475"	"ENSG00000073536"	"NLE1"	"hsa:54475; O60868; Q59GJ8; Q9BU54; Q9NVX2"	"17q12 copy number variation syndrome"	""	"1"	"0"	"23.5"	"25.1"	"34.2"	"31.2"	"29.9"	"33.2"	"53.6"	"65.8"	"83.8"	"191.4"	"229.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75663"	"TIP41-like protein OS=Homo sapiens OX=9606 GN=TIPRL PE=1 SV=2"	"0.000"	""	"14"	"3"	"5"	"3"	"272"	"31.4"	"5.91"	"701.17"	"8.83"	"2"	"3"	"stress response;signal transduction;other biological processes"	"cytosol"	""	"Pf04176"	"261726"	"ENSG00000143155"	"TIPRL"	"B2R8V3; hsa:261726; O75663; Q5HYB2; Q8IZ86"	"Ciliary landscape"	""	"1"	"0"	"199.0"	"197.3"	"265.4"	"316.8"	"204.5"	"229.9"	"325.7"	"327.1"	"387.7"	"653.4"	"780.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94979"	"Protein transport protein Sec31A OS=Homo sapiens OX=9606 GN=SEC31A PE=1 SV=3"	"0.000"	""	"2"	"3"	"5"	"3"	"1220"	"132.9"	"6.89"	"594.89"	"8.81"	"2"	"3"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf12931"	"22872"	"ENSG00000138674"	"SEC31A"	"B4DIW6; B7ZKZ7; B7ZL00; H7C2W3; hsa:22872; O94979; Q17RR5; Q5H9P6; Q5XG74; Q659G7; Q6ZU90; Q7LCX9; Q86TJ0; Q8IZH4; Q9P048; Q9P0A6; Q9UM05; Q9UM06"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"MHC class II antigen presentation; Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport; XBP1(S) activates chaperone genes; Antigen Presentation: Folding, assembly and peptide loading of class I MHC"	"6"	"0"	"112.3"	"109.7"	"131.8"	"149.5"	"111.7"	"96.6"	"223.3"	"237.3"	"378.1"	"1180.9"	"1661.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0A0"	"RNA cytidine acetyltransferase OS=Homo sapiens OX=9606 GN=NAT10 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1025"	"115.7"	"8.27"	"860.81"	"8.80"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05127, Pf08351, Pf13718, Pf13725"	"55226"	"ENSG00000135372"	"NAT10"	"B4DFD5; E7ESU4; E9PMN9; hsa:55226; Q86WK5; Q9C0F4; Q9H0A0; Q9HA61; Q9NVF2"	"Metapathway biotransformation Phase I and II"	"rRNA modification in the nucleus and cytosol"	"2"	"0"	"90.8"	"87.2"	"105.9"	"134.6"	"92.6"	"96.9"	"153.3"	"169.9"	"225.5"	"439.0"	"571.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6N3"	"UPF0690 protein C1orf52 OS=Homo sapiens OX=9606 GN=C1orf52 PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"182"	"20.6"	"5.21"	"881.42"	"8.79"	"2"	"2"	""	"nucleus"	""	"Pf15559"	"148423"	"ENSG00000162642"	"C1orf52"	"B3KX89; hsa:148423; Q8N6N3; Q8TDK5; Q8TDK6"	""	""	"0"	"0"	"157.3"	"163.0"	"180.6"	"175.6"	"155.6"	"148.7"	"200.0"	"200.4"	"250.7"	"401.8"	"524.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5MNZ6"	"WD repeat domain phosphoinositide-interacting protein 3 OS=Homo sapiens OX=9606 GN=WDR45B PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"344"	"38.1"	"7.59"	"986.82"	"8.79"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"56270"	"ENSG00000141580"	"WDR45B"	"A0A024R8U4; A0A218N098; hsa:56270; O95328; Q2MCP6; Q5MNZ6; Q6IBN2"	""	"Macroautophagy"	"1"	"0"	"39.3"	"46.8"	"52.2"	"58.6"	"44.3"	"50.4"	"88.4"	"109.7"	"161.4"	"420.4"	"475.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRV9"	"Heme-binding protein 1 OS=Homo sapiens OX=9606 GN=HEBP1 PE=1 SV=1"	"0.000"	""	"17"	"2"	"3"	"2"	"189"	"21.1"	"5.80"	"420.49"	"8.79"	"1"	"2"	"other biological processes"	"non-structural extracellular;other cell component"	"other molecular function"	"Pf04832"	"50865"	"ENSG00000013583"	"HEBP1"	"A8K1G2; hsa:50865; Q9NRV9; Q9Y5Z5"	""	"G alpha (i) signalling events; Formyl peptide receptors bind formyl peptides and many other ligands"	"2"	"0"	"245.1"	"265.3"	"312.9"	"412.6"	"246.2"	"220.9"	"360.8"	"386.5"	"437.4"	"617.6"	"760.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06744"	"Glucose-6-phosphate isomerase OS=Homo sapiens OX=9606 GN=GPI PE=1 SV=4"	"0.000"	""	"5"	"3"	"6"	"3"	"558"	"63.1"	"8.32"	"991.56"	"8.79"	"3"	"3"	"other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00342"	"2821"	"ENSG00000105220"	"GPI"	"B4DG39; hsa:2821; P06744; Q9BRD3; Q9BSK5; Q9UHE6"	"Cori cycle; Clear cell renal cell carcinoma pathways; Metabolic reprogramming in colon cancer; Aerobic glycolysis; N-glycan biosynthesis; Disorders of fructose metabolism; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders; UDP-derived sugars synthesis in fibroblasts"	"Neutrophil degranulation; Glycolysis; Gluconeogenesis; TP53 Regulates Metabolic Genes"	"13"	"0"	"164.5"	"126.1"	"190.8"	"282.0"	"154.9"	"177.5"	"285.1"	"285.2"	"526.1"	"1475.6"	"2433.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60293"	"Zinc finger C3H1 domain-containing protein OS=Homo sapiens OX=9606 GN=ZFC3H1 PE=1 SV=3"	"0.000"	""	"3"	"4"	"5"	"4"	"1989"	"226.2"	"8.13"	"898.71"	"8.79"	"2"	"3"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf10650"	"196441"	"ENSG00000133858"	"ZFC3H1"	"hsa:196441; O60293; Q6GMU1; Q6P2S9; Q6ZV36; Q96BE7"	""	""	"0"	"0"	"124.5"	"171.8"	"162.9"	"165.2"	"121.4"	"124.8"	"192.4"	"197.6"	"230.0"	"426.8"	"513.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03188"	"Centromere protein C OS=Homo sapiens OX=9606 GN=CENPC PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"943"	"106.8"	"9.39"	"657.94"	"8.78"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11699, Pf15620, Pf15622"	"1060"	"ENSG00000145241"	"CENPC"	"hsa:1060; Q03188; Q6PIR0; Q8IW27; Q9P0M5"	""	"Separation of Sister Chromatids; Deposition of new CENPA-containing nucleosomes at the centromere; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"75.1"	"66.5"	"77.2"	"99.2"	"68.2"	"71.0"	"124.7"	"133.6"	"185.8"	"346.0"	"374.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13136"	"Liprin-alpha-1 OS=Homo sapiens OX=9606 GN=PPFIA1 PE=1 SV=1"	"0.000"	""	"5"	"5"	"9"	"3"	"1202"	"135.7"	"6.29"	"2519.36"	"8.78"	"5"	"3"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8500"	"ENSG00000131626"	"PPFIA1"	"A6NLE3; hsa:8500; Q13135; Q13136; Q14567; Q8N4I2"	""	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	"6"	"2"	"161.2"	"150.6"	"176.6"	"230.0"	"163.4"	"149.4"	"254.9"	"273.0"	"359.6"	"681.8"	"1005.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZM3"	"Intersectin-2 OS=Homo sapiens OX=9606 GN=ITSN2 PE=1 SV=3"	"0.000"	""	"2"	"3"	"6"	"3"	"1697"	"193.3"	"8.12"	"975.74"	"8.77"	"3"	"3"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00168, Pf00621, Pf07653, Pf12763, Pf14604, Pf16652"	"50618"	"ENSG00000198399"	"ITSN2"	"hsa:50618; O95062; Q15812; Q9HAK4; Q9NXE6; Q9NYG0; Q9NZM2; Q9NZM3; Q9ULG4"	""	"Cargo recognition for clathrin-mediated endocytosis; RHOU GTPase cycle"	"3"	"0"	"13.1"	"8.2"	"22.3"	"21.9"	"22.3"	"48.5"	"116.8"	"133.3"	"157.6"	"212.6"	"211.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13984"	"General transcription factor IIF subunit 2 OS=Homo sapiens OX=9606 GN=GTF2F2 PE=1 SV=2"	"0.000"	""	"12"	"3"	"6"	"3"	"249"	"28.4"	"9.23"	"1022.20"	"8.76"	"3"	"3"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02270, Pf17683"	"2963"	"ENSG00000188342"	"GTF2F2"	"A6NNS5; hsa:2963; P13984; Q5W0H3"	"Eukaryotic transcription initiation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; Viral Messenger RNA Synthesis; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM"	"33"	"0"	"145.9"	"137.1"	"162.9"	"227.2"	"144.7"	"151.6"	"254.8"	"248.5"	"340.1"	"758.8"	"1183.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96LT9"	"RNA-binding region-containing protein 3 OS=Homo sapiens OX=9606 GN=RNPC3 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"517"	"58.5"	"7.72"	"869.13"	"8.76"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"55599"	"ENSG00000185946"	"RNPC3"	"A8K1C9; D3DT74; hsa:55599; Q5TZ87; Q96FK7; Q96JI8; Q96LT9; Q9NSU7; Q9NXX2"	""	"mRNA Splicing - Minor Pathway"	"1"	"0"	"55.4"	"40.1"	"66.4"	"87.2"	"55.5"	"49.7"	"94.3"	"98.8"	"131.8"	"250.0"	"346.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q02952"	"A-kinase anchor protein 12 OS=Homo sapiens OX=9606 GN=AKAP12 PE=1 SV=4"	""	""	"3"	"3"	"3"	"3"	"1782"	"191.4"	"4.41"	""	"8.76"	""	"3"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf03832, Pf10522"	"9590"	"ENSG00000131016"	"AKAP12"	"hsa:9590; O00310; O00498; Q02952; Q4LE68; Q5SZ80; Q5TGN1; Q68D82; Q99970"	"G protein signaling pathways"	"RHOD GTPase cycle; RHOF GTPase cycle"	"3"	"0"	"142.9"	"125.3"	"163.5"	"173.7"	"119.2"	"139.8"	"169.1"	"177.6"	"186.0"	"380.9"	"724.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY63"	"Angiomotin-like protein 1 OS=Homo sapiens OX=9606 GN=AMOTL1 PE=1 SV=1"	"0.000"	""	"3"	"3"	"5"	"1"	"956"	"106.5"	"7.11"	"541.25"	"8.74"	"2"	"3"	"cell-cell signaling;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf12240"	"154810"	"ENSG00000166025"	"AMOTL1"	"hsa:154810; Q63HK7; Q8IY63; Q8NDN0; Q8TEN8; Q8WXD1; Q96CM5"	""	"Signaling by Hippo"	"1"	"0"	"40.3"	"30.6"	"39.7"	"37.6"	"28.1"	"41.0"	"45.0"	"47.7"	"49.0"	"174.4"	"98.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP79"	"Vacuolar protein sorting-associated protein VTA1 homolog OS=Homo sapiens OX=9606 GN=VTA1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"307"	"33.9"	"6.29"	"864.95"	"8.71"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04652, Pf18097"	"51534"	"ENSG00000009844"	"VTA1"	"B4DW55; E1P594; E7ETQ7; hsa:51534; Q5TGM1; Q6IAE8; Q9H0R2; Q9H3K9; Q9NP79; Q9P0Q0"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	"103.5"	"76.0"	"112.2"	"124.4"	"100.2"	"103.7"	"158.0"	"151.7"	"155.5"	"736.4"	"1633.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18858"	"DNA ligase 1 OS=Homo sapiens OX=9606 GN=LIG1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"919"	"101.7"	"5.62"	"391.73"	"8.69"	"1"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01068, Pf04675, Pf04679"	"3978"	"ENSG00000105486"	"LIG1"	"B2RAI8; B4DTU4; hsa:3978; P18858; Q2TB12; Q32P23"	"Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Gap-filling DNA repair synthesis and ligation in TC-NER; Early Phase of HIV Life Cycle; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Processive synthesis on the lagging strand; Gap-filling DNA repair synthesis and ligation in GG-NER; Processive synthesis on the C-strand of the telomere; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"14"	"0"	"25.8"	"10.7"	"36.6"	"31.8"	"26.0"	"30.1"	"42.1"	"46.5"	"52.3"	"168.0"	"410.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15446"	"DNA-directed RNA polymerase I subunit RPA34 OS=Homo sapiens OX=9606 GN=CD3EAP PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"510"	"55.0"	"8.51"	"903.26"	"8.69"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf08208"	"10849"	"ENSG00000117877"	"POLR1G"	"hsa:10849; O15446; Q32N11; Q7Z5U2; Q9UPF6"	"2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"6"	"0"	"111.2"	"74.1"	"130.5"	"132.1"	"103.0"	"101.6"	"205.6"	"202.6"	"288.9"	"433.3"	"555.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI35"	"InaD-like protein OS=Homo sapiens OX=9606 GN=PATJ PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"1801"	"196.2"	"4.94"	"302.86"	"8.67"	"1"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf00595, Pf09045"	""	"ENSG00000132849"	"PATJ"	"O15249; O43742; O60833; Q5VUA5; Q5VUA6; Q5VUA7; Q5VUA8; Q5VUA9; Q5VUB0; Q8NI35; Q8WU78; Q9H3N9"	""	"Tight junction interactions; SARS-CoV-2 targets PDZ proteins in cell-cell junction"	"2"	"0"	"117.0"	"92.9"	"142.2"	"154.9"	"115.8"	"114.0"	"176.6"	"180.6"	"253.7"	"632.2"	"882.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62834"	"Ras-related protein Rap-1A OS=Homo sapiens OX=9606 GN=RAP1A PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"1"	"184"	"21.0"	"6.67"	"505.14"	"8.65"	"1"	"2"	"cell-cell signaling;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"5906"	"ENSG00000116473"	"RAP1A"	"hsa:5906; P10113; P62834"	"Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Androgen receptor network in prostate cancer; Brain-derived neurotrophic factor (BDNF) signaling pathway; Common pathways underlying drug addiction; Focal adhesion; Hepatocyte growth factor receptor signaling; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Ras signaling; EGF/EGFR signaling pathway; Leukocyte-intrinsic Hippo pathway functions; DNA repair pathways, full network; GDNF signaling; Interferon type I signaling pathways; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling"	"Neutrophil degranulation; Signaling by BRAF and RAF1 fusions; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Rap1 signalling; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; ARMS-mediated activation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; MET activates RAP1 and RAC1"	"34"	"1"	"119.1"	"96.4"	"121.7"	"173.4"	"104.5"	"99.0"	"172.1"	"199.0"	"269.8"	"502.7"	"663.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16204"	"Coiled-coil domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CCDC6 PE=1 SV=2"	"0.000"	""	"8"	"2"	"4"	"2"	"474"	"53.3"	"7.34"	"934.39"	"8.65"	"2"	"2"	"cell organization and biogenesis"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf09755"	"8030"	"ENSG00000108091"	"CCDC6"	"hsa:8030; Q15250; Q16204; Q6GSG7"	"Retinoblastoma gene in cancer; Mesodermal commitment pathway; 16p11.2 proximal deletion syndrome"	""	"3"	"0"	"84.8"	"70.3"	"84.5"	"111.0"	"81.9"	"80.4"	"145.6"	"138.0"	"208.1"	"475.5"	"678.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T653"	"39S ribosomal protein L2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL2 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"305"	"33.3"	"11.30"	"998.13"	"8.64"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf00181, Pf03947"	"51069"	"ENSG00000112651"	"MRPL2"	"B2RC56; hsa:51069; Q5T653; Q8WUL1; Q96Q56; Q9Y311"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"25.2"	"13.9"	"25.9"	"27.9"	"25.5"	"21.4"	"34.1"	"43.8"	"43.1"	"109.6"	"184.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKA9"	"Polypyrimidine tract-binding protein 2 OS=Homo sapiens OX=9606 GN=PTBP2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"9"	"2"	"531"	"57.5"	"8.66"	"2220.78"	"8.64"	"3"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf11835, Pf13893"	"58155"	"ENSG00000117569"	"PTBP2"	"hsa:58155; Q8N0Z1; Q8N160; Q8NFB0; Q8NFB1; Q969N9; Q96Q76; Q9UKA9"	"Genes targeted by miRNAs in adipocytes; mRNA processing"	""	"2"	"0"	"151.9"	"125.7"	"153.6"	"189.9"	"132.7"	"133.9"	"198.1"	"229.0"	"279.4"	"654.7"	"1093.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H993"	"Damage-control phosphatase ARMT1 OS=Homo sapiens OX=9606 GN=ARMT1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"441"	"51.1"	"5.76"	"586.80"	"8.64"	"1"	"2"	"other metabolic processes;stress response"	""	"other molecular function"	"Pf01937"	"79624"	"ENSG00000146476"	"ARMT1"	"hsa:79624; Q96FC6; Q9H993; Q9UFY5"	""	""	"0"	"0"	"38.1"	"29.3"	"45.7"	"56.5"	"37.1"	"33.6"	"94.3"	"101.9"	"167.6"	"619.2"	"1249.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00403"	"Transcription initiation factor IIB OS=Homo sapiens OX=9606 GN=GTF2B PE=1 SV=1"	"0.000"	""	"11"	"2"	"4"	"2"	"316"	"34.8"	"8.35"	"961.36"	"8.63"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00382, Pf08271"	"2959"	"ENSG00000137947"	"GTF2B"	"A8K1A7; hsa:2959; Q00403; Q5JS30"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	"43.1"	"46.8"	"48.4"	"58.4"	"47.9"	"51.7"	"74.8"	"85.2"	"109.6"	"199.2"	"201.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15276"	"Rab GTPase-binding effector protein 1 OS=Homo sapiens OX=9606 GN=RABEP1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"862"	"99.2"	"5.01"	"901.46"	"8.61"	"2"	"2"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf03528, Pf09311"	"9135"	"ENSG00000029725"	"RABEP1"	"B2RAG7; hsa:9135; O95369; Q15276; Q8IVX3"	"GDNF signaling"	"TBC/RABGAPs"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIL1"	"Short coiled-coil protein OS=Homo sapiens OX=9606 GN=SCOC PE=1 SV=2"	"0.000"	""	"18"	"2"	"3"	"2"	"159"	"18.0"	"8.85"	"317.44"	"8.59"	"1"	"2"	"other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	""	"Pf10224"	"60592"	"ENSG00000153130"	"SCOC"	"B7WPH7; D3DNY7; E9PB65; hsa:60592; Q6P5T9; Q7L2Y0; Q7Z4P2; Q96JY9; Q9BZB2; Q9UIL1"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"174.7"	"138.0"	"199.9"	"227.7"	"163.3"	"184.9"	"242.3"	"241.3"	"309.6"	"716.8"	"1007.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15437"	"Protein transport protein Sec23B OS=Homo sapiens OX=9606 GN=SEC23B PE=1 SV=2"	"0.000"	""	"2"	"1"	"5"	"1"	"767"	"86.4"	"6.89"	"1397.57"	"8.59"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"10483"	"ENSG00000101310"	"SEC23B"	"D3DW33; hsa:10483; Q15437; Q503A9; Q5W183; Q9BS15; Q9BSI2; Q9H1D7"	"Sterol regulatory element-binding proteins (SREBP) signaling"	""	"1"	"0"	"40.2"	"46.1"	"57.8"	"76.0"	"38.4"	"29.5"	"87.0"	"75.4"	"94.3"	"246.0"	"389.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFW8"	"N-acylneuraminate cytidylyltransferase OS=Homo sapiens OX=9606 GN=CMAS PE=1 SV=2"	"0.000"	""	"4"	"2"	"6"	"2"	"434"	"48.3"	"7.93"	"934.37"	"8.58"	"2"	"2"	"other metabolic processes"	"nucleus"	"other molecular function"	"Pf02348"	"55907"	"ENSG00000111726"	"CMAS"	"hsa:55907; Q8NFW8; Q96AX5; Q9NQZ0"	""	"Sialic acid metabolism"	"1"	"0"	"129.4"	"192.6"	"125.3"	"171.2"	"149.0"	"94.7"	"293.9"	"325.8"	"392.6"	"634.9"	"632.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNE7"	"E3 ubiquitin-protein ligase CHIP OS=Homo sapiens OX=9606 GN=STUB1 PE=1 SV=2"	"0.000"	""	"13"	"4"	"6"	"4"	"303"	"34.8"	"5.87"	"1038.57"	"8.58"	"3"	"3"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf04564, Pf12895, Pf18391"	"10273"	"ENSG00000103266"	"STUB1"	"A2IDB9; hsa:10273; O60526; Q969U2; Q9HBT1; Q9UNE7"	"Androgen receptor signaling pathway; Parkin-ubiquitin proteasomal system pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Regulation of TNFR1 signaling; Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Downregulation of TGF-beta receptor signaling"	"10"	"0"	"338.9"	"438.6"	"307.8"	"506.7"	"294.4"	"249.5"	"622.3"	"749.4"	"917.5"	"2839.5"	"3928.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35606"	"Coatomer subunit beta' OS=Homo sapiens OX=9606 GN=COPB2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"906"	"102.4"	"5.27"	"1044.27"	"8.57"	"2"	"2"	"transport"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00400, Pf04053"	"9276"	"ENSG00000184432"	"COPB2"	"B4DZI8; hsa:9276; P35606"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"131.1"	"122.9"	"144.7"	"140.8"	"104.1"	"136.6"	"197.6"	"198.9"	"244.7"	"607.4"	"1027.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00193"	"Small acidic protein OS=Homo sapiens OX=9606 GN=SMAP PE=1 SV=1"	"0.000"	""	"26"	"3"	"5"	"3"	"183"	"20.3"	"4.72"	"1432.79"	"8.53"	"2"	"2"	""	""	""	"Pf15477"	"10944"	"ENSG00000110696"	"SMAP"	"B2RD28; hsa:10944; O00193"	""	""	"0"	"0"	"601.9"	"574.0"	"555.4"	"643.3"	"535.2"	"541.8"	"683.5"	"649.1"	"707.2"	"887.6"	"1058.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13555"	"Calcium/calmodulin-dependent protein kinase type II subunit gamma OS=Homo sapiens OX=9606 GN=CAMK2G PE=1 SV=4"	"0.000"	""	"7"	"3"	"5"	"1"	"558"	"62.6"	"7.83"	"1005.17"	"8.52"	"3"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf08332"	"818"	"ENSG00000148660"	"CAMK2G"	"A0A0A0MS52; A0A0A0MT11; hsa:818; O00561; O15378; Q13279; Q13282; Q13555; Q13556; Q5SQZ3; Q5SQZ4; Q5SWX4; Q7KYX5; Q8N4I3; Q8NIA4"	"Energy metabolism; Myometrial relaxation and contraction pathways; NO/cGMP/PKG mediated neuroprotection; Splicing factor NOVA regulated synaptic proteins; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Disruption of postsynaptic signaling by CNV; Neuroinflammation and glutamatergic signaling; Calcium regulation in cardiac cells; ErbB signaling pathway"	"Ion transport by P-type ATPases; Assembly and cell surface presentation of NMDA receptors; Ion homeostasis; Signaling by BRAF and RAF1 fusions; Interferon gamma signaling; RAF activation; Ras activation upon Ca2+ influx through NMDA receptor; Regulation of MECP2 expression and activity; Unblocking of NMDA receptors, glutamate binding and activation; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; Trafficking of AMPA receptors; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; Phase 0 - rapid depolarisation; HSF1-dependent transactivation; CaMK IV-mediated phosphorylation of CREB; CREB1 phosphorylation through the activation of CaMKII/CaMKK/CaMKIV cascasde"	"31"	"0"	"41.3"	"43.0"	"41.8"	"58.1"	"42.9"	"32.9"	"89.4"	"85.3"	"128.8"	"300.5"	"441.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UK7"	"E3 ubiquitin-protein ligase ZNF598 OS=Homo sapiens OX=9606 GN=ZNF598 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"904"	"98.6"	"8.40"	"449.68"	"8.49"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"enzyme regulator activity;translation activity;other molecular function"	""	"90850"	""	"ZNF598"	"hsa:90850; Q86UK7; Q8IW49; Q8N3D9; Q96FG3; Q9H7J3"	""	""	"0"	"0"	"24.4"	"27.9"	"25.6"	"38.6"	"30.4"	"29.7"	"40.1"	"33.8"	"39.4"	"67.3"	"68.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41223"	"Protein BUD31 homolog OS=Homo sapiens OX=9606 GN=BUD31 PE=1 SV=2"	"0.000"	""	"26"	"5"	"7"	"5"	"144"	"17.0"	"8.82"	"2083.32"	"8.48"	"5"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01125"	"8896"	"ENSG00000106245"	"BUD31"	"A4D274; B7Z4S9; D6W5S6; hsa:8896; P41223; Q6IB53; Q9UDV1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"255.9"	"259.0"	"288.3"	"391.4"	"287.4"	"259.3"	"449.5"	"516.5"	"663.5"	"1367.0"	"1902.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9N8"	"Probable RNA-binding protein EIF1AD OS=Homo sapiens OX=9606 GN=EIF1AD PE=1 SV=1"	"0.000"	""	"25"	"3"	"5"	"3"	"165"	"19.0"	"5.21"	"591.50"	"8.47"	"2"	"3"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01176"	"84285"	"ENSG00000175376"	"EIF1AD"	"B2R4N5; hsa:84285; Q8N9N8; Q9BSC1"	""	""	"0"	"0"	"168.4"	"110.6"	"217.4"	"245.6"	"164.0"	"156.1"	"232.7"	"228.7"	"259.8"	"546.3"	"735.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99871"	"HAUS augmin-like complex subunit 7 OS=Homo sapiens OX=9606 GN=HAUS7 PE=1 SV=3"	"0.000"	""	"8"	"2"	"4"	"2"	"368"	"40.8"	"4.83"	"835.26"	"8.45"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"28.3"	"27.2"	"36.6"	"41.0"	"29.0"	"25.5"	"53.0"	"58.2"	"79.3"	"209.9"	"242.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYW2"	"Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3"	"0.000"	""	"1"	"3"	"5"	"3"	"2564"	"287.4"	"6.14"	"601.21"	"8.45"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00856, Pf08236, Pf17907"	"29072"	"ENSG00000181555"	"SETD2"	"hsa:29072; O75397; O75405; Q17RW8; Q5BKS9; Q5QGN2; Q69YI5; Q6IN64; Q6ZN53; Q6ZS25; Q8N3R0; Q8TCN0; Q9BYW2; Q9C0D1; Q9H696; Q9NZW9"	"Histone modifications; Mesodermal commitment pathway; Mesodermal commitment pathway; Pathways affected in adenoid cystic carcinoma; Clear cell renal cell carcinoma pathways; Type 2 papillary renal cell carcinoma; Pleural mesothelioma"	"PKMTs methylate histone lysines"	"8"	"0"	"185.8"	"135.8"	"246.4"	"246.9"	"185.4"	"186.3"	"298.0"	"310.1"	"362.2"	"881.3"	"1204.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09110"	"3-ketoacyl-CoA thiolase, peroxisomal OS=Homo sapiens OX=9606 GN=ACAA1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"4"	"2"	"424"	"44.3"	"8.44"	"879.51"	"8.45"	"2"	"2"	"other metabolic processes"	"non-structural extracellular;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"30"	"ENSG00000060971"	"ACAA1"	"G5E935; hsa:30; P09110; Q96CA6"	"PPAR-alpha pathway; Nuclear receptors meta-pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX)"	"Neutrophil degranulation; TYSND1 cleaves peroxisomal proteins; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of very long chain fatty acids"	"11"	"0"	"75.2"	"60.8"	"93.2"	"118.0"	"73.9"	"76.9"	"120.8"	"121.9"	"167.6"	"398.9"	"684.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14643"	"Inositol 1,4,5-trisphosphate receptor type 1 OS=Homo sapiens OX=9606 GN=ITPR1 PE=1 SV=3"	"0.000"	""	"1"	"3"	"5"	"2"	"2758"	"313.7"	"6.04"	"1072.46"	"8.45"	"3"	"2"	"cell-cell signaling;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf01365, Pf02815, Pf08454, Pf08709"	"3708"	"ENSG00000150995"	"ITPR1"	"E7EPX7; E9PDE9; hsa:3708; Q14643; Q14660; Q99897"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; G protein signaling pathways; Cell-type dependent selectivity of CCK2R signaling; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Vitamin D-sensitive calcium signaling in depression; PKC-gamma calcium signaling pathway in ataxia; Type I collagen synthesis in the context of osteogenesis imperfecta; GPR143 in melanocytes and retinal pigment epithelium cells; STING pathway in Kawasaki-like disease and COVID-19; Alzheimer's disease; GDNF signaling; Calcium regulation in cardiac cells; 15q25 copy number variation; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; cGMP effects; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Ca2+ pathway; VEGFR2 mediated cell proliferation; Elevation of cytosolic Ca2+ levels; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation; Effects of PIP2 hydrolysis"	"34"	"0"	"28.4"	"32.3"	"41.9"	"48.9"	"33.0"	"34.7"	"69.0"	"66.0"	"111.6"	"304.3"	"422.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19387"	"DNA-directed RNA polymerase II subunit RPB3 OS=Homo sapiens OX=9606 GN=POLR2C PE=1 SV=2"	"0.000"	""	"12"	"2"	"4"	"2"	"275"	"31.4"	"4.92"	"1115.57"	"8.42"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01000, Pf01193"	"5432"	"ENSG00000102978"	"POLR2C"	"hsa:5432; O15161; P19387"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Primary ovarian insufficiency"	"Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; mRNA Splicing - Major Pathway; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"44"	"0"	"116.3"	"92.7"	"132.2"	"193.4"	"119.0"	"121.9"	"187.8"	"195.2"	"257.9"	"511.0"	"681.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P01116"	"GTPase KRas OS=Homo sapiens OX=9606 GN=KRAS PE=1 SV=1"	"0.000"	""	"20"	"3"	"5"	"3"	"189"	"21.6"	"6.77"	"770.34"	"8.42"	"2"	"3"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071"	"3845"	"ENSG00000133703"	"KRAS"	"A8K8Z5; B0LPF9; hsa:3845; P01116; P01118; Q96D10"	"IL-5 signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; RalA downstream regulated genes; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; Extracellular vesicle-mediated signaling in recipient cells; RAC1/PAK1/p38/MMP2 pathway; G protein signaling pathways; BDNF-TrkB signaling; MAPK signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Thermogenesis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Synaptic signaling pathways associated with autism spectrum disorder; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; EGFR tyrosine kinase inhibitor resistance; Kisspeptin/kisspeptin receptor system in the ovary; MAPK pathway in congenital thyroid cancer; Regulation of actin cytoskeleton; Alzheimer's disease; Autophagy in pancreatic ductal adenocarcinoma; JAK-STAT signaling in the regulation of Beta-cells; ErbB signaling pathway; DNA damage response (only ATM dependent); Serotonin receptor 2 and ELK-SRF/GATA4 signaling"	"Signaling by CSF3 (G-CSF); Signaling by CSF1 (M-CSF) in myeloid cells; RAS processing; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAS GAP mutants; Signaling by RAS GTPase mutants; RUNX3 regulates p14-ARF"	"57"	"0"	"59.4"	"59.9"	"79.1"	"101.8"	"63.4"	"78.3"	"197.4"	"224.7"	"261.8"	"364.1"	"457.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00308"	"NEDD4-like E3 ubiquitin-protein ligase WWP2 OS=Homo sapiens OX=9606 GN=WWP2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"870"	"98.9"	"7.12"	"755.50"	"8.40"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00397, Pf00632"	"11060"	"ENSG00000198373"	"WWP2"	"A6NEP1; B2R706; B4DTL5; F5H213; H3BRF3; hsa:11060; I3RSG8; O00308; Q6ZTQ5; Q96CZ2; Q9BWN6"	""	"RHOQ GTPase cycle; Regulation of PTEN stability and activity; RHOJ GTPase cycle; NOTCH3 Activation and Transmission of Signal to the Nucleus; RHOU GTPase cycle"	"5"	"0"	"10.7"	"8.1"	"11.6"	"17.3"	"8.1"	"8.1"	"27.4"	"19.9"	"40.1"	"163.8"	"246.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQA1"	"Methylosome protein 50 OS=Homo sapiens OX=9606 GN=WDR77 PE=1 SV=1"	"0.000"	""	"9"	"3"	"6"	"3"	"342"	"36.7"	"5.17"	"831.73"	"8.40"	"3"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400"	"79084"	"ENSG00000116455"	"WDR77"	"B3KMW6; B4DP38; hsa:79084; Q3LID2; Q53FU2; Q6JZZ5; Q96GK4; Q9BQA1; Q9BWY3"	""	"snRNP Assembly; RMTs methylate histone arginines"	"2"	"0"	"55.0"	"51.1"	"67.7"	"104.8"	"60.2"	"47.2"	"109.8"	"103.3"	"134.7"	"426.6"	"722.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46781"	"40S ribosomal protein S9 OS=Homo sapiens OX=9606 GN=RPS9 PE=1 SV=3"	"0.000"	""	"20"	"5"	"8"	"5"	"194"	"22.6"	"10.65"	"1636.80"	"8.40"	"5"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00163, Pf01479"	"6203"	"ENSG00000170889; ENSG00000274005; ENSG00000274626; ENSG00000274646; ENSG00000274950; ENSG00000275323; ENSG00000277079; ENSG00000277359; ENSG00000278081; ENSG00000278270"	"RPS9"	"A9C4C1; hsa:6203; P46781; Q4QRK7; Q9BVZ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Peptide chain elongation; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"20"	"0"	"438.3"	"482.9"	"472.3"	"577.7"	"448.6"	"477.7"	"727.2"	"814.0"	"1067.6"	"2445.0"	"3494.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96DH6"	"RNA-binding protein Musashi homolog 2 OS=Homo sapiens OX=9606 GN=MSI2 PE=1 SV=1"	""	""	"10"	"2"	"2"	"2"	"328"	"35.2"	"8.48"	""	"8.38"	""	"2"	"developmental processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"124540"	"ENSG00000153944"	"MSI2"	"hsa:124540; Q7Z6M7; Q8N9T4; Q96DH6"	""	"RHOBTB2 GTPase cycle"	"1"	"0"	"144.9"	"165.0"	"158.3"	"239.5"	"169.2"	"131.5"	"275.5"	"318.7"	"389.8"	"744.9"	"885.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14531"	"Dihydropyrimidinase-related protein 4 OS=Homo sapiens OX=9606 GN=DPYSL4 PE=1 SV=2"	"0.000"	""	"6"	"3"	"6"	"3"	"572"	"61.8"	"7.09"	"979.95"	"8.38"	"3"	"3"	"developmental processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf01979"	"10570"	"ENSG00000151640"	"DPYSL4"	"B2RMQ1; D3DRG5; hsa:10570; O00240; O14531; Q5T0Q7"	""	"CRMPs in Sema3A signaling"	"1"	"0"	"32.5"	"32.1"	"39.4"	"50.0"	"32.3"	"34.5"	"102.6"	"102.5"	"175.7"	"1073.3"	"1725.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7LBC6"	"Lysine-specific demethylase 3B OS=Homo sapiens OX=9606 GN=KDM3B PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1761"	"191.5"	"7.18"	"830.95"	"8.37"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02373"	"51780"	"ENSG00000120733"	"KDM3B"	"A6H8X7; hsa:51780; Q7LBC6; Q9BVH6; Q9BW93; Q9BZ52; Q9NYF4; Q9UPS0"	"Thermogenesis"	"HDMs demethylate histones"	"2"	"0"	"112.5"	"112.3"	"101.5"	"133.3"	"90.8"	"102.3"	"160.9"	"168.1"	"222.8"	"477.9"	"667.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42224"	"Signal transducer and activator of transcription 1-alpha/beta OS=Homo sapiens OX=9606 GN=STAT1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"750"	"87.3"	"6.05"	"736.47"	"8.35"	"2"	"2"	"cell cycle OR cell proliferation;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00017, Pf01017, Pf02864, Pf02865, Pf12162"	"6772"	"ENSG00000115415"	"STAT1"	"A8K989; B2RCA0; D2KFR8; D3DPI7; hsa:6772; P42224; Q53S88; Q53XW4; Q68D00; Q9UDL5"	"IL-5 signaling pathway; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Type III interferon signaling; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; AGE/RAGE pathway; Allograft rejection; Interleukin-11 signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Endoderm differentiation; Kit receptor signaling pathway; IL6 signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; IL-4 signaling pathway; p38 MAPK signaling pathway; Immune response to tuberculosis; Ebola virus infection in host; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; IL-10 anti-inflammatory signaling pathway ; Overview of interferons-mediated signaling pathway; Measles virus infection; Tryptophan metabolism; Hepatitis B infection; Endochondral ossification; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; Endochondral ossification with skeletal dysplasias; TGF-beta receptor signaling in skeletal dysplasias; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; IL-2 signaling pathway; SARS coronavirus and innate immunity; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; CCL18 signaling pathway; Th17 cell differentiation pathway; Inflammatory bowel disease signaling; 2q13 copy number variation syndrome; TROP2 regulatory signaling; IL-26 signaling pathways; JAK-STAT signaling in the regulation of Beta-cells; TGF-beta receptor signaling; EPO receptor signaling; Interferon type I signaling pathways; Type II interferon signaling; Toll-like receptor signaling pathway"	"Signaling by SCF-KIT; Signaling by CSF1 (M-CSF) in myeloid cells; Regulation of RUNX2 expression and activity; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Downstream signal transduction; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Interleukin-4 and Interleukin-13 signaling; Growth hormone receptor signaling; Interleukin-6 signaling; Interferon alpha/beta signaling; Inactivation of CSF3 (G-CSF) signaling; Signaling by cytosolic FGFR1 fusion mutants; NOTCH3 Intracellular Domain Regulates Transcription; Interleukin-20 family signaling; Interleukin-35 Signalling; Interleukin-27 signaling; Interleukin-9 signaling; Interleukin-21 signaling"	"79"	"0"	"61.1"	"61.5"	"74.5"	"80.7"	"64.5"	"62.0"	"133.1"	"143.2"	"222.0"	"602.8"	"781.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6M9"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9 OS=Homo sapiens OX=9606 GN=NDUFB9 PE=1 SV=3"	"0.000"	""	"9"	"1"	"4"	"1"	"179"	"21.8"	"8.38"	"863.40"	"8.32"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4715"	"ENSG00000147684"	"NDUFB9"	"B2R8M6; hsa:4715; Q9UQE8; Q9Y6M9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial immune response to SARS-CoV-2; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"58.4"	"65.8"	"67.6"	"86.1"	"56.1"	"52.1"	"88.5"	"121.4"	"166.5"	"350.2"	"446.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0E9"	"Bromodomain-containing protein 8 OS=Homo sapiens OX=9606 GN=BRD8 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1235"	"135.3"	"4.60"	"808.97"	"8.32"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00439"	"10902"	"ENSG00000112983"	"BRD8"	"hsa:10902; O43178; Q15355; Q58AB0; Q59GN0; Q969M9; Q9H0E9"	""	"HATs acetylate histones"	"1"	"0"	"114.7"	"92.4"	"120.4"	"107.4"	"91.2"	"112.8"	"128.6"	"152.0"	"156.8"	"314.6"	"438.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09496"	"Clathrin light chain A OS=Homo sapiens OX=9606 GN=CLTA PE=1 SV=1"	"0.000"	""	"16"	"5"	"8"	"5"	"248"	"27.1"	"4.51"	"1519.71"	"8.31"	"5"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01086"	"1211"	"ENSG00000122705"	"CLTA"	"A8K4W3; B4DIN1; F5H6N3; hsa:1211; P09496; Q2XPN5; Q53XZ1"	"Synaptic vesicle pathway; Ebola virus infection in host; Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Recycling pathway of L1; MHC class II antigen presentation; Lysosome Vesicle Biogenesis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Retrograde neurotrophin signalling; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation; Entry of Influenza Virion into Host Cell via Endocytosis; Formation of annular gap junctions"	"17"	"0"	"1646.7"	"1336.7"	"1533.5"	"1665.6"	"1278.9"	"1291.5"	"1658.5"	"1643.3"	"1655.1"	"2221.8"	"2567.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26196"	"Probable ATP-dependent RNA helicase DDX6 OS=Homo sapiens OX=9606 GN=DDX6 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"483"	"54.4"	"8.66"	"1008.36"	"8.30"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271"	"1656"	"ENSG00000110367"	"DDX6"	"hsa:1656; P26196; Q5D048"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"140.8"	"105.2"	"137.7"	"182.2"	"132.9"	"139.3"	"211.3"	"227.1"	"283.7"	"636.9"	"885.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY7"	"Pentatricopeptide repeat domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=PTCD3 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"2"	"689"	"78.5"	"6.42"	"864.02"	"8.30"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;translational apparatus;nucleus"	"translation activity;nucleic acid binding activity"	"Pf13041, Pf13812"	"55037"	"ENSG00000132300"	"PTCD3"	"A6NHD2; D6W5M1; hsa:55037; Q597H0; Q658Y9; Q96EY7; Q9BUZ8; Q9NWL0"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"47.6"	"47.5"	"51.0"	"54.4"	"51.6"	"52.8"	"70.7"	"68.9"	"94.3"	"185.4"	"269.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92820"	"Gamma-glutamyl hydrolase OS=Homo sapiens OX=9606 GN=GGH PE=1 SV=2"	"0.000"	""	"11"	"3"	"6"	"3"	"318"	"35.9"	"7.11"	"886.46"	"8.30"	"3"	"3"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07722"	"8836"	"ENSG00000137563"	"GGH"	"hsa:8836; Q92820"	"Fluoropyrimidine activity"	"Neutrophil degranulation"	"2"	"0"	"53.8"	"70.7"	"67.5"	"66.9"	"63.3"	"78.5"	"171.5"	"190.7"	"271.6"	"753.3"	"1073.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14789"	"Golgin subfamily B member 1 OS=Homo sapiens OX=9606 GN=GOLGB1 PE=1 SV=2"	"0.000"	""	"1"	"4"	"7"	"3"	"3259"	"375.8"	"5.00"	"1121.71"	"8.28"	"4"	"3"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi"	"nucleic acid binding activity"	""	"2804"	"ENSG00000173230"	"GOLGB1"	"B2ZZ91; D3DN92; E7EP74; F1T0J2; hsa:2804; Q14398; Q14789"	""	"Golgi Associated Vesicle Biogenesis; COPI-mediated anterograde transport; Signaling by FLT3 fusion proteins"	"3"	"0"	"40.9"	"36.9"	"46.0"	"59.6"	"38.4"	"30.9"	"81.3"	"97.4"	"147.8"	"415.0"	"683.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3YEC7"	"Rab-like protein 6 OS=Homo sapiens OX=9606 GN=RABL6 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"729"	"79.5"	"5.22"	"422.04"	"8.27"	"1"	"2"	""	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00071"	"55684"	"ENSG00000196642"	"RABL6"	"A8QVZ7; A8QVZ8; C6K8I4; C6K8I5; hsa:55684; Q3YEC7; Q4F968; Q5T5R7; Q8IWK1; Q8TCL4; Q8WU94; Q96SR8; Q9BU21; Q9H935"	""	""	"0"	"0"	"36.0"	"24.7"	"45.5"	"44.2"	"28.5"	"31.5"	"54.7"	"63.6"	"67.0"	"275.9"	"325.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWZ6"	"Bardet-Biedl syndrome 7 protein OS=Homo sapiens OX=9606 GN=BBS7 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"715"	"80.3"	"6.05"	"937.83"	"8.27"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"55212"	"ENSG00000138686"	"BBS7"	"hsa:55212; Q4W5P8; Q8IWZ6; Q8N581; Q9NVI4"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"BBSome-mediated cargo-targeting to cilium"	"6"	"0"	"30.3"	"34.5"	"26.4"	"41.1"	"26.7"	"32.7"	"146.2"	"184.3"	"282.1"	"577.1"	"685.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12899"	"Tripartite motif-containing protein 26 OS=Homo sapiens OX=9606 GN=TRIM26 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"539"	"62.1"	"5.03"	"985.70"	"8.27"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"7726"	"ENSG00000137313; ENSG00000226060; ENSG00000228881; ENSG00000230230; ENSG00000231002; ENSG00000231641; ENSG00000234046; ENSG00000234127"	"TRIM26"	"A6NG96; hsa:7726; Q12899; Q5SRL2"	""	"Interferon gamma signaling"	"1"	"0"	"33.6"	"41.7"	"45.7"	"44.2"	"29.2"	"24.4"	"55.7"	"57.0"	"72.2"	"140.5"	"172.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15599"	"Na(+)/H(+) exchange regulatory cofactor NHE-RF2 OS=Homo sapiens OX=9606 GN=SLC9A3R2 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"337"	"37.4"	"7.93"	"654.19"	"8.27"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00595, Pf09007"	"9351"	"ENSG00000065054"	"NHERF2"	"D3DU84; D3DU85; H3BSV6; hsa:9351; O00272; O00556; Q15599; Q3KQY7"	""	""	"0"	"0"	"30.9"	"35.3"	"29.7"	"41.3"	"31.3"	"30.0"	"35.8"	"37.7"	"39.4"	"45.0"	"45.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54578"	"Ubiquitin carboxyl-terminal hydrolase 14 OS=Homo sapiens OX=9606 GN=USP14 PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"494"	"56.0"	"5.30"	"909.41"	"8.27"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00443"	"9097"	"ENSG00000101557"	"USP14"	"B7Z4N8; hsa:9097; J3QRZ5; P54578; Q53XY5"	""	"Ub-specific processing proteases; Regulation of NF-kappa B signaling"	"2"	"0"	"25.5"	"21.1"	"32.1"	"50.3"	"33.8"	"26.6"	"54.0"	"51.5"	"64.1"	"256.8"	"792.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZI7"	"Upstream-binding protein 1 OS=Homo sapiens OX=9606 GN=UBP1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"1"	"540"	"60.5"	"6.35"	"740.93"	"8.26"	"2"	"2"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04516, Pf18016"	"7342"	"ENSG00000153560"	"UBP1"	"hsa:7342; Q68CT0; Q86Y57; Q9H8V0; Q9NZI7; Q9UD76; Q9UD78"	""	""	"0"	"0"	"16.1"	"18.1"	"18.0"	"23.9"	"12.8"	"15.2"	"34.9"	"38.4"	"61.4"	"136.9"	"167.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15294"	"UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit OS=Homo sapiens OX=9606 GN=OGT PE=1 SV=3"	"0.000"	""	"5"	"4"	"5"	"4"	"1046"	"116.9"	"6.70"	"822.33"	"8.26"	"3"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00515, Pf13181, Pf13414, Pf13424, Pf13844"	"8473"	"ENSG00000147162"	"OGT"	"hsa:8473; O15294; Q7Z3K0; Q8WWM8; Q96CC1; Q9UG57"	"Ectoderm differentiation; Ectoderm differentiation; Pleural mesothelioma"	"UCH proteinases; Formation of WDR5-containing histone-modifying complexes; Regulation of necroptotic cell death; HATs acetylate histones"	"8"	"0"	"106.7"	"99.4"	"130.2"	"161.1"	"94.7"	"93.9"	"167.8"	"180.9"	"229.6"	"654.2"	"1085.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2G2"	"STE20-like serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=SLK PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"1235"	"142.6"	"5.15"	"379.84"	"8.24"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12474"	"9748"	"ENSG00000065613"	"SLK"	"D3DRA0; D3DRA1; hsa:9748; O00211; Q6P1Z4; Q86WU7; Q86WW1; Q92603; Q9H2G2; Q9NQL0; Q9NQL1"	"TAR syndrome"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"4"	"0"	"30.3"	"28.1"	"37.2"	"42.6"	"20.3"	"25.5"	"49.1"	"43.3"	"61.6"	"212.2"	"344.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16949"	"Stathmin OS=Homo sapiens OX=9606 GN=STMN1 PE=1 SV=3"	"0.000"	""	"17"	"2"	"4"	"2"	"149"	"17.3"	"5.97"	"797.20"	"8.22"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00836"	"3925"	"ENSG00000117632"	"STMN1"	"A2A2D1; B2R4E7; B7Z8N4; D3DPJ5; hsa:3925; P16949"	"Microtubule cytoskeleton regulation; Retinoblastoma gene in cancer; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; EGF/EGFR signaling pathway; IL-18 signaling pathway"	"Nuclear signaling by ERBB4"	"7"	"0"	"102.4"	"87.2"	"141.3"	"173.0"	"98.9"	"107.1"	"150.1"	"166.4"	"166.5"	"320.4"	"777.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2H8"	"Peptidyl-prolyl cis-trans isomerase-like 3 OS=Homo sapiens OX=9606 GN=PPIL3 PE=1 SV=1"	"0.000"	""	"28"	"5"	"7"	"5"	"161"	"18.1"	"6.79"	"1378.35"	"8.18"	"4"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00160"	"53938"	"ENSG00000240344"	"PPIL3"	"hsa:53938; Q86WF9; Q96IA9; Q9BXZ1; Q9H2H8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"367.3"	"379.7"	"448.7"	"489.1"	"348.2"	"400.0"	"702.8"	"704.6"	"931.6"	"1941.8"	"2263.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96KP1"	"Exocyst complex component 2 OS=Homo sapiens OX=9606 GN=EXOC2 PE=1 SV=1"	"0.000"	""	"6"	"4"	"7"	"4"	"924"	"104.0"	"6.90"	"1671.36"	"8.18"	"4"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01833, Pf15469"	"55770"	"ENSG00000112685"	"EXOC2"	"B2RBE6; hsa:55770; Q5JPC8; Q96AN6; Q96KP1; Q9NUZ8; Q9UJM7"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"7"	"0"	"19.7"	"22.7"	"40.3"	"40.9"	"27.0"	"30.5"	"145.5"	"173.5"	"403.7"	"955.9"	"1038.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H974"	"Queuine tRNA-ribosyltransferase accessory subunit 2 OS=Homo sapiens OX=9606 GN=QTRT2 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"415"	"46.7"	"6.81"	"404.16"	"8.17"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;mitochondrion;other cell component"	"other molecular function"	"Pf01702"	"79691"	"ENSG00000151576"	"QTRT2"	"A6NGE9; B7Z472; B7Z5R2; hsa:79691; J3KR78; Q6IA59; Q9H974"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"41.2"	"32.5"	"46.0"	"64.8"	"37.7"	"32.5"	"95.4"	"89.8"	"146.3"	"403.5"	"592.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61024"	"Cyclin-dependent kinases regulatory subunit 1 OS=Homo sapiens OX=9606 GN=CKS1B PE=1 SV=1"	"0.000"	""	"33"	"2"	"4"	"2"	"79"	"9.7"	"8.94"	"825.11"	"8.16"	"2"	"2"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01111"	"1163"	"ENSG00000173207"	"CKS1B"	"hsa:1163; P33551; P61024"	"Small cell lung cancer"	"SCF(Skp2)-mediated degradation of p27/p21; Cyclin D associated events in G1"	"3"	"0"	"93.6"	"149.0"	"72.1"	"116.7"	"77.2"	"93.9"	"181.8"	"233.2"	"307.8"	"953.3"	"1457.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P36959"	"GMP reductase 1 OS=Homo sapiens OX=9606 GN=GMPR PE=1 SV=1"	""	""	"9"	"2"	"2"	"1"	"345"	"37.4"	"7.06"	""	"8.15"	""	"2"	"other metabolic processes;stress response"	"cytosol;other cell component"	"other molecular function"	"Pf00478"	"2766"	"ENSG00000137198"	"GMPR"	"hsa:2766; P36959; Q96HQ6"	""	"Purine salvage"	"1"	"0"	"2.9"	"2.7"	"2.1"	"6.8"	"2.3"	"5.3"	"22.3"	"24.1"	"43.7"	"154.1"	"252.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NXE4"	"Sphingomyelin phosphodiesterase 4 OS=Homo sapiens OX=9606 GN=SMPD4 PE=1 SV=3"	""	""	"3"	"1"	"2"	"1"	"866"	"97.7"	"8.27"	""	"8.15"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"other molecular function"	"Pf14724"	"55627"	"ENSG00000136699"	"SMPD4"	"B1PBA3; B4DM23; B4DQ31; B4DRB8; B4DWK7; B4E0L6; E7ESA2; E9PCE6; hsa:55627; Q6FI76; Q6P1P7; Q6ZT43; Q9H0M2; Q9NW20; Q9NWL2; Q9NXE4; Q9P2C9"	""	"Glycosphingolipid metabolism"	"1"	"0"	"4.0"	"6.7"	"4.8"	"8.3"	"3.5"	"5.6"	"9.1"	"6.0"	"11.0"	"27.5"	"36.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41214"	"Eukaryotic translation initiation factor 2D OS=Homo sapiens OX=9606 GN=EIF2D PE=1 SV=3"	"0.000"	""	"7"	"3"	"4"	"3"	"584"	"64.7"	"7.65"	"801.90"	"8.13"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01253, Pf17832"	"1939"	"ENSG00000143486"	"EIF2D"	"hsa:1939; P41214; Q5SY40; Q8IXV3; Q96DG3; Q96TG7; Q9NR27; Q9NSN0; Q9NV18; Q9NZ21"	""	""	"0"	"0"	"129.8"	"120.7"	"168.8"	"175.4"	"137.6"	"137.0"	"252.8"	"235.0"	"316.6"	"560.8"	"625.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22415"	"Upstream stimulatory factor 1 OS=Homo sapiens OX=9606 GN=USF1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"1"	"310"	"33.5"	"5.54"	"769.97"	"8.12"	"2"	"2"	"stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7391"	"ENSG00000158773"	"USF1"	"B2RBZ4; hsa:7391; P22415; Q5SY46; Q7Z5Y1"	"7q11.23 copy number variation syndrome; Familial hyperlipidemia type 2"	"Estrogen-dependent gene expression"	"3"	"0"	"9.5"	"7.9"	"13.4"	"16.4"	"11.2"	"10.8"	"18.0"	"18.7"	"27.1"	"77.2"	"105.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IU81"	"Interferon regulatory factor 2-binding protein 1 OS=Homo sapiens OX=9606 GN=IRF2BP1 PE=1 SV=1"	""	""	"8"	"2"	"2"	"2"	"584"	"61.6"	"8.18"	""	"8.12"	""	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00097, Pf11261"	"26145"	"ENSG00000170604"	"IRF2BP1"	"hsa:26145; Q53EL7; Q6DC95; Q8IU81; Q9BRZ9; Q9Y4P4"	""	""	"0"	"0"	"61.8"	"59.7"	"65.8"	"66.7"	"51.7"	"71.0"	"159.7"	"155.3"	"232.5"	"506.9"	"771.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBX8"	"Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma OS=Homo sapiens OX=9606 GN=PIP4K2C PE=1 SV=3"	"0.000"	""	"8"	"3"	"5"	"3"	"421"	"47.3"	"6.84"	"673.70"	"8.11"	"2"	"3"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf01504"	"79837"	"ENSG00000166908"	"PIP4K2C"	"B2RDL3; B4DM11; B4DY44; hsa:79837; Q8TBX8; Q9H6N2"	"Regulation of actin cytoskeleton"	"Synthesis of PIPs at the plasma membrane; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"5"	"0"	"128.5"	"111.4"	"150.6"	"153.7"	"152.0"	"179.4"	"556.3"	"577.6"	"643.9"	"544.0"	"524.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15532"	"Protein SSXT OS=Homo sapiens OX=9606 GN=SS18 PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"418"	"45.9"	"6.46"	"1086.73"	"8.10"	"2"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05030"	"6760"	"ENSG00000141380"	"SS18"	"B0YJ95; hsa:6760; Q15532; Q16404; Q4VAX1; Q9BXC6"	""	""	"0"	"0"	"44.6"	"40.7"	"51.1"	"54.6"	"46.5"	"28.9"	"52.2"	"57.0"	"66.4"	"129.8"	"162.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9GZS1"	"DNA-directed RNA polymerase I subunit RPA49 OS=Homo sapiens OX=9606 GN=POLR1E PE=1 SV=3"	""	""	"7"	"2"	"2"	"2"	"419"	"47.2"	"8.94"	""	"8.10"	""	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06870"	"64425"	"ENSG00000137054"	"POLR1E"	"hsa:64425; Q5VZT3; Q8NBA9; Q96L20; Q9GZS1"	"Pyrimidine metabolism; Eukaryotic transcription initiation; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"8"	"0"	"76.3"	"64.7"	"84.8"	"107.8"	"82.3"	"69.6"	"217.3"	"255.6"	"364.5"	"662.1"	"750.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92796"	"Disks large homolog 3 OS=Homo sapiens OX=9606 GN=DLG3 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"817"	"90.3"	"7.03"	"758.74"	"8.09"	"2"	"2"	"cell-cell signaling;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf10600"	"1741"	"ENSG00000082458"	"DLG3"	"B4E0H1; D3DVU5; hsa:1741; Q5JUW6; Q5JUW7; Q92796; Q9ULI8"	""	"Assembly and cell surface presentation of NMDA receptors; RAF/MAP kinase cascade; Neurexins and neuroligins; Ras activation upon Ca2+ influx through NMDA receptor; Unblocking of NMDA receptors, glutamate binding and activation; Synaptic adhesion-like molecules; Negative regulation of NMDA receptor-mediated neuronal transmission; Long-term potentiation; NrCAM interactions; Activation of Ca-permeable Kainate Receptor"	"10"	"0"	"86.1"	"63.5"	"111.7"	"121.7"	"91.4"	"92.7"	"227.5"	"232.4"	"326.3"	"719.7"	"714.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43166"	"Signal-induced proliferation-associated 1-like protein 1 OS=Homo sapiens OX=9606 GN=SIPA1L1 PE=1 SV=4"	"0.000"	""	"3"	"3"	"5"	"3"	"1804"	"199.9"	"8.19"	"503.37"	"8.08"	"2"	"3"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity"	"Pf02145, Pf11881"	"26037"	"ENSG00000197555"	"SIPA1L1"	"hsa:26037; J3KP19; O43166; O95321; Q9UDU4; Q9UNU4"	""	"Neurexins and neuroligins"	"1"	"0"	"53.1"	"39.8"	"53.6"	"71.1"	"48.1"	"46.6"	"79.2"	"94.2"	"127.7"	"339.5"	"479.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX24"	"H/ACA ribonucleoprotein complex subunit 2 OS=Homo sapiens OX=9606 GN=NHP2 PE=1 SV=1"	"0.000"	""	"19"	"2"	"4"	"2"	"153"	"17.2"	"8.22"	"1043.79"	"8.06"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01248"	"55651"	"ENSG00000145912"	"NHP2"	"A6NKY8; hsa:55651; Q9NX24; Q9P095"	""	"rRNA modification in the nucleus and cytosol; Telomere Extension By Telomerase"	"2"	"0"	"166.0"	"145.0"	"186.4"	"189.2"	"135.9"	"152.9"	"295.4"	"323.4"	"452.3"	"907.3"	"1156.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2R9"	"28S ribosomal protein S7, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS7 PE=1 SV=2"	"0.000"	""	"10"	"2"	"4"	"2"	"242"	"28.1"	"9.99"	"799.98"	"8.05"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00177"	"51081"	"ENSG00000125445"	"MRPS7"	"B2R9N5; hsa:51081; Q53GD6; Q9Y2R9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"87.1"	"84.3"	"114.4"	"136.6"	"99.2"	"93.9"	"137.3"	"132.7"	"170.0"	"305.3"	"444.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94903"	"Pyridoxal phosphate homeostasis protein OS=Homo sapiens OX=9606 GN=PLPBP PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"275"	"30.3"	"7.50"	"752.35"	"8.05"	"2"	"2"	""	"cytosol;other cell component"	"other molecular function"	"Pf01168"	"11212"	"ENSG00000147471"	"PLPBP"	"hsa:11212; O94903; Q6FI94"	""	""	"0"	"0"	"85.8"	"64.6"	"103.1"	"119.0"	"78.1"	"82.5"	"207.8"	"218.6"	"431.4"	"1258.3"	"1554.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NHR9"	"Structural maintenance of chromosomes flexible hinge domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SMCHD1 PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"2"	"2005"	"226.2"	"7.30"	"1093.67"	"8.02"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06470, Pf13589"	"23347"	"ENSG00000101596"	"SMCHD1"	"A6NHR9; hsa:23347; O75141; Q6AHX6; Q6ZTQ8; Q9H6Q2; Q9UG39"	""	""	"0"	"0"	"86.4"	"74.9"	"89.6"	"142.6"	"89.7"	"76.6"	"146.1"	"160.9"	"232.6"	"535.4"	"789.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NAV1"	"Pre-mRNA-splicing factor 38A OS=Homo sapiens OX=9606 GN=PRPF38A PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"312"	"37.5"	"9.96"	"900.29"	"8.01"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf03371, Pf12871"	"84950"	"ENSG00000134748"	"PRPF38A"	"hsa:84950; Q8NAV1; Q96JW1; Q9BVZ8"	"MECP2 and associated Rett syndrome"	"mRNA Splicing - Major Pathway"	"2"	"0"	"88.0"	"79.2"	"109.1"	"123.4"	"90.0"	"88.0"	"154.3"	"150.1"	"205.9"	"618.0"	"816.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02224"	"Centromere-associated protein E OS=Homo sapiens OX=9606 GN=CENPE PE=1 SV=2"	"0.000"	""	"1"	"3"	"5"	"2"	"2701"	"316.2"	"5.64"	"608.89"	"8.01"	"2"	"3"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"1062"	"ENSG00000138778"	"CENPE"	"A6NKY9; A8K2U7; hsa:1062; Q02224; Q4LE75"	"Regulation of sister chromatid separation at the metaphase-anaphase transition"	"RHO GTPases Activate Formins; COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"5.5"	"7.3"	"7.6"	"11.4"	"6.8"	"6.0"	"12.0"	"10.8"	"16.6"	"36.9"	"43.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15435"	"Protein phosphatase 1 regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PPP1R7 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"360"	"41.5"	"4.91"	"843.99"	"7.99"	"2"	"2"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf14580"	"5510"	"ENSG00000115685"	"PPP1R7"	"B4DFD4; B5MCY6; hsa:5510; Q15435; Q9UQE5; Q9UQE6; Q9Y6K4"	"2q37 copy number variation syndrome"	""	"1"	"0"	"28.2"	"34.2"	"44.6"	"83.4"	"28.7"	"27.7"	"65.6"	"57.9"	"81.2"	"369.2"	"659.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P53004"	"Biliverdin reductase A OS=Homo sapiens OX=9606 GN=BLVRA PE=1 SV=2"	""	""	"8"	"1"	"2"	"1"	"296"	"33.4"	"6.44"	""	"7.99"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01408, Pf09166"	"644"	"ENSG00000106605"	"BLVRA"	"A8K747; hsa:644; O95019; P53004; Q86UX0; Q96QL4; Q9BRW8"	"IL-10 anti-inflammatory signaling pathway"	"Cytoprotection by HMOX1; Heme degradation"	"3"	"0"	"9.3"	"8.4"	"14.1"	"11.2"	"14.0"	"8.2"	"10.2"	"16.6"	"29.3"	"115.6"	"309.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34896"	"Serine hydroxymethyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=SHMT1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"1"	"483"	"53.0"	"7.71"	"729.13"	"7.98"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00464"	"6470"	"ENSG00000176974; ENSG00000284320"	"SHMT1"	"B4DPM9; D3DXD0; hsa:6470; P34896; Q96HY0; Q9UMD1; Q9UMD2"	"Glycine metabolism; Folate metabolism; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Clear cell renal cell carcinoma pathways; Male infertility; Neuroinflammation and glutamatergic signaling; Metabolic Epileptic Disorders; Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Metabolism of folate and pterines; Carnitine synthesis"	"11"	"0"	"45.6"	"37.0"	"52.9"	"56.5"	"48.5"	"47.7"	"61.0"	"61.5"	"87.4"	"148.3"	"234.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWI1"	"LIM domain only protein 7 OS=Homo sapiens OX=9606 GN=LMO7 PE=1 SV=3"	"0.000"	""	"4"	"5"	"6"	"5"	"1683"	"192.6"	"8.09"	"1161.08"	"7.97"	"3"	"3"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00307, Pf00412, Pf00595, Pf15949"	"4008"	"ENSG00000136153"	"LMO7"	"E9PLH4; hsa:4008; O15462; O95346; Q5TBK6; Q8WWI1; Q9UKC1; Q9UQM5; Q9Y6A7"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; Signaling by ALK fusions and activated point mutants"	"3"	"0"	"333.2"	"298.1"	"304.3"	"358.0"	"272.8"	"305.7"	"361.2"	"384.9"	"408.7"	"721.0"	"797.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCD5"	"Nuclear receptor coactivator 5 OS=Homo sapiens OX=9606 GN=NCOA5 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"579"	"65.5"	"9.60"	"841.43"	"7.96"	"2"	"2"	"signal transduction;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	""	"57727"	"ENSG00000124160"	"NCOA5"	"B2RTV9; E1P5R0; hsa:57727; Q6HA99; Q9H1F2; Q9H2T2; Q9H4Y9; Q9HCD5"	""	""	"0"	"0"	"136.6"	"113.5"	"144.0"	"165.4"	"127.3"	"112.8"	"171.7"	"180.6"	"183.6"	"284.7"	"393.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62266"	"40S ribosomal protein S23 OS=Homo sapiens OX=9606 GN=RPS23 PE=1 SV=3"	"0.000"	""	"8"	"1"	"4"	"1"	"143"	"15.8"	"10.49"	"893.63"	"7.96"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00164"	"6228"	"ENSG00000186468"	"RPS23"	"hsa:6228; P39028; P62266; Q6IB08"	"Cytoplasmic ribosomal proteins"	"GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"143.2"	"180.2"	"169.7"	"229.9"	"135.4"	"156.9"	"310.5"	"337.0"	"466.1"	"1088.6"	"1607.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51948"	"CDK-activating kinase assembly factor MAT1 OS=Homo sapiens OX=9606 GN=MNAT1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"309"	"35.8"	"6.09"	"275.16"	"7.96"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"enzyme regulator activity;other molecular function"	"Pf06391, Pf17121"	"4331"	"ENSG00000020426"	"MNAT1"	"G3V1U8; hsa:4331; P51948; Q15817; Q6ICQ7"	"Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"38"	"0"	"51.2"	"49.3"	"79.7"	"91.0"	"54.9"	"46.0"	"167.3"	"185.2"	"311.2"	"954.5"	"1405.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FF9"	"Sororin OS=Homo sapiens OX=9606 GN=CDCA5 PE=1 SV=1"	"0.000"	""	"12"	"3"	"7"	"3"	"252"	"27.6"	"9.61"	"1155.60"	"7.95"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09666"	"113130"	"ENSG00000146670"	"CDCA5"	"A8K625; hsa:113130; Q96FF9"	""	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; Establishment of Sister Chromatid Cohesion"	"3"	"0"	"982.3"	"822.1"	"956.3"	"1090.6"	"806.9"	"831.2"	"1017.9"	"1011.2"	"1148.2"	"1676.0"	"1788.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY1"	"DnaJ homolog subfamily A member 3, mitochondrial OS=Homo sapiens OX=9606 GN=DNAJA3 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"480"	"52.5"	"9.26"	"940.86"	"7.94"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00226, Pf00684, Pf01556"	"9093"	"ENSG00000103423; ENSG00000276726"	"DNAJA3"	"B2RAJ5; B4DI33; E7ES32; hsa:9093; O75472; Q8WUJ6; Q8WXJ3; Q96D76; Q96EY1; Q96IV1; Q9NYH8"	""	""	"0"	"0"	"79.4"	"71.6"	"87.4"	"138.3"	"95.9"	"93.0"	"158.8"	"167.8"	"236.5"	"486.2"	"686.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y697"	"Cysteine desulfurase, mitochondrial OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"457"	"50.2"	"8.31"	"986.80"	"7.94"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00266"	"9054"	"ENSG00000244005"	"NFS1"	"B3KMA5; B4DXK9; E1P5R8; F5GYK5; hsa:9054; Q6P0L8; Q9NTZ5; Q9Y481; Q9Y697"	"Iron-sulfur cluster biogenesis"	""	"1"	"0"	"38.3"	"97.5"	"41.1"	"42.5"	"30.7"	"33.1"	"86.0"	"96.6"	"134.8"	"334.0"	"478.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14254"	"Flotillin-2 OS=Homo sapiens OX=9606 GN=FLOT2 PE=1 SV=2"	"0.000"	""	"10"	"3"	"5"	"3"	"428"	"47.0"	"5.25"	"1197.49"	"7.94"	"3"	"2"	"cell adhesion;transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	""	"Pf01145"	"2319"	"ENSG00000132589"	"FLOT2"	"hsa:2319; Q14254"	"Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"RHOA GTPase cycle; RHOB GTPase cycle; Regulation of necroptotic cell death; RND1 GTPase cycle; RND3 GTPase cycle; RHOC GTPase cycle; Synaptic adhesion-like molecules"	"10"	"0"	"27.3"	"25.7"	"29.6"	"46.8"	"24.2"	"29.9"	"55.0"	"65.4"	"81.2"	"273.1"	"542.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQP7"	"Mitochondrial genome maintenance exonuclease 1 OS=Homo sapiens OX=9606 GN=MGME1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"344"	"39.4"	"7.68"	"881.96"	"7.93"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf12705"	"92667"	"ENSG00000125871"	"MGME1"	"B2RDG5; D3DW29; hsa:92667; Q96SW3; Q9BQP7"	"Primary ovarian insufficiency"	""	"1"	"0"	"21.2"	"18.8"	"20.1"	"28.6"	"26.1"	"31.5"	"59.0"	"81.3"	"136.1"	"396.2"	"502.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15853"	"Upstream stimulatory factor 2 OS=Homo sapiens OX=9606 GN=USF2 PE=1 SV=1"	"0.000"	""	"7"	"3"	"6"	"2"	"346"	"36.9"	"5.10"	"802.96"	"7.90"	"3"	"3"	"transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"7392"	"ENSG00000105698"	"USF2"	"hsa:7392; O00671; O00709; Q05750; Q07952; Q15851; Q15852; Q15853; Q6FI33; Q6YI47"	"Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4)"	"Estrogen-dependent gene expression"	"2"	"1"	"396.6"	"349.7"	"406.5"	"483.9"	"358.3"	"282.9"	"600.1"	"606.2"	"791.4"	"1613.5"	"1987.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35998"	"26S proteasome regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMC2 PE=1 SV=3"	"0.000"	""	"6"	"3"	"5"	"3"	"433"	"48.6"	"5.95"	"1302.69"	"7.90"	"3"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"5701"	"ENSG00000161057"	"PSMC2"	"A4D0Q1; B7Z5E2; hsa:5701; P35998; Q3LIA5; Q9UDI3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Hedgehog 'on' state; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; The role of GTSE1 in G2/M progression after G2 checkpoint; Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"98.2"	"92.1"	"94.9"	"111.3"	"72.1"	"73.8"	"110.2"	"117.9"	"139.4"	"369.7"	"752.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14950"	"Myosin regulatory light chain 12B OS=Homo sapiens OX=9606 GN=MYL12B PE=1 SV=2"	"0.000"	""	"29"	"3"	"4"	"3"	"172"	"19.8"	"4.84"	"864.83"	"7.89"	"2"	"2"	"other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08976, Pf13405"	"103910; 10627"	"ENSG00000118680"	"MYL12B"	"D3DUH6; hsa:103910; O14950; Q13182; Q7Z5Z4"	"Thyroid stimulating hormone (TSH) signaling pathway; Focal adhesion"	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; Smooth Muscle Contraction; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"9"	"0"	"62.4"	"55.4"	"72.0"	"84.9"	"52.5"	"53.8"	"101.1"	"121.4"	"144.1"	"909.3"	"1918.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFY9"	"Kelch repeat and BTB domain-containing protein 8 OS=Homo sapiens OX=9606 GN=KBTBD8 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"601"	"68.8"	"6.29"	"1388.76"	"7.88"	"3"	"2"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf00651, Pf01344, Pf07707"	"84541"	"ENSG00000163376"	"KBTBD8"	"B4DTW6; hsa:84541; Q8NFY9; Q96JI5"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"2"	"0"	"16.8"	"12.4"	"13.2"	"29.0"	"18.3"	"23.7"	"125.5"	"148.8"	"205.5"	"328.1"	"398.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00273"	"DNA fragmentation factor subunit alpha OS=Homo sapiens OX=9606 GN=DFFA PE=1 SV=1"	"0.000"	""	"6"	"2"	"6"	"2"	"331"	"36.5"	"4.79"	"740.55"	"7.86"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02017, Pf09033"	"1676"	"ENSG00000160049"	"DFFA"	"hsa:1676; O00273; Q5T6G5; Q5T6G6; Q96I97; Q9Y6C6"	"Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Acute viral myocarditis"	"Apoptosis induced DNA fragmentation"	"4"	"0"	"167.8"	"130.5"	"222.7"	"266.8"	"155.9"	"118.7"	"241.2"	"255.9"	"271.3"	"537.5"	"988.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60245"	"Protocadherin-7 OS=Homo sapiens OX=9606 GN=PCDH7 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1069"	"116.0"	"5.19"	"833.14"	"7.85"	"2"	"2"	"cell adhesion"	"plasma membrane;other membranes"	"other molecular function"	"Pf00028, Pf08266, Pf08374"	"5099"	"ENSG00000169851"	"PCDH7"	"hsa:5099; O60245; O60246; O60247; Q4W5C4"	""	"RHOA GTPase cycle; RHOB GTPase cycle; Platelet degranulation"	"3"	"0"	"28.9"	"26.6"	"30.8"	"41.9"	"25.1"	"26.6"	"80.0"	"85.8"	"158.3"	"830.1"	"1290.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZL7"	"Ribosome biogenesis protein WDR12 OS=Homo sapiens OX=9606 GN=WDR12 PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"423"	"47.7"	"5.90"	"701.58"	"7.84"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08154"	"55759"	"ENSG00000138442"	"WDR12"	"B3KPA9; hsa:55759; Q96HU0; Q9GZL7; Q9NV80; Q9NYI8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"65.5"	"56.5"	"75.3"	"109.0"	"63.6"	"55.7"	"127.1"	"131.3"	"200.6"	"602.7"	"827.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13693"	"Translationally-controlled tumor protein OS=Homo sapiens OX=9606 GN=TPT1 PE=1 SV=1"	"0.000"	""	"17"	"2"	"3"	"2"	"172"	"19.6"	"4.93"	"490.95"	"7.84"	"1"	"2"	"transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00838"	"7178"	"ENSG00000133112"	"TPT1"	"B2R7E5; hsa:7178; P13693; Q6YLS2; Q7Z4J4; Q8TBK7; Q96EE2; Q9UC70"	""	""	"0"	"0"	"16.1"	"14.8"	"20.9"	"29.6"	"17.3"	"17.0"	"38.6"	"46.2"	"77.9"	"198.0"	"731.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16718"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 OS=Homo sapiens OX=9606 GN=NDUFA5 PE=1 SV=3"	"0.000"	""	"24"	"2"	"4"	"2"	"116"	"13.5"	"5.99"	"570.97"	"7.84"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf04716"	"4698"	"ENSG00000128609"	"NDUFA5"	"B2RD98; hsa:4698; Q16718; Q5H9R2; Q6IRX7"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis; RHOG GTPase cycle"	"7"	"0"	"58.2"	"61.2"	"84.7"	"112.6"	"62.3"	"67.4"	"143.1"	"120.4"	"193.6"	"463.3"	"623.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P1U0"	"DNA-directed RNA polymerase I subunit RPA12 OS=Homo sapiens OX=9606 GN=ZNRD1 PE=1 SV=1"	"0.000"	""	"19"	"2"	"3"	"2"	"126"	"13.9"	"5.06"	"276.25"	"7.84"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01096"	"30834"	"ENSG00000066379; ENSG00000206502; ENSG00000224859; ENSG00000233795; ENSG00000235176; ENSG00000235443; ENSG00000236808; ENSG00000236949"	"POLR1H"	"hsa:30834; Q9P1U0"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"7"	"0"	"65.9"	"39.9"	"70.1"	"76.1"	"61.2"	"56.5"	"211.0"	"227.1"	"372.4"	"745.7"	"1032.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31930"	"Cytochrome b-c1 complex subunit 1, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"480"	"52.6"	"6.37"	"355.06"	"7.82"	"1"	"2"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00675, Pf05193"	"7384"	"ENSG00000010256"	"UQCRC1"	"B2R7R8; hsa:7384; P31930; Q96DD2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"44.6"	"43.8"	"61.3"	"66.9"	"35.8"	"37.8"	"77.3"	"77.7"	"91.0"	"184.1"	"232.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13356"	"RING-type E3 ubiquitin-protein ligase PPIL2 OS=Homo sapiens OX=9606 GN=PPIL2 PE=1 SV=1"	"0.000"	""	"5"	"3"	"5"	"3"	"520"	"58.8"	"8.78"	"638.04"	"7.82"	"2"	"3"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00160"	"23759"	"ENSG00000100023"	"PPIL2"	"hsa:23759; Q13356; Q13357; Q8TAH2; Q9BWR8"	""	"mRNA Splicing - Major Pathway; Basigin interactions"	"2"	"0"	"201.9"	"206.2"	"200.6"	"259.4"	"184.9"	"207.3"	"289.0"	"305.5"	"414.0"	"871.5"	"1168.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UX04"	"Spliceosome-associated protein CWC27 homolog OS=Homo sapiens OX=9606 GN=CWC27 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"472"	"53.8"	"5.80"	"750.79"	"7.82"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00160"	"10283"	"ENSG00000153015"	"CWC27"	"hsa:10283; O60529; O60530; Q6UX04; Q96EM3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"37.0"	"44.1"	"32.2"	"37.5"	"32.4"	"32.4"	"50.0"	"42.1"	"58.3"	"97.4"	"110.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62714"	"Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PPP2CB PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"309"	"35.6"	"5.43"	"394.54"	"7.80"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00149"	"5516"	"ENSG00000104695"	"PPP2CB"	"D3DSV4; hsa:5516; P11082; P62714; Q6FHK5"	"Serotonin transporter activity; Dopamine metabolism; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; Exercise-induced circadian regulation; PI3K-Akt signaling pathway; 16p11.2 proximal deletion syndrome; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome; Monoamine transport"	"Regulation of TP53 Degradation; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RAF activation; Negative regulation of MAPK pathway; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Spry regulation of FGF signaling; MASTL Facilitates Mitotic Progression; Regulation of glycolysis by fructose 2,6-bisphosphate metabolism; Platelet sensitization by LDL; CTLA4 inhibitory signaling; Inhibition of replication initiation of damaged DNA by RB1/E2F1; DARPP-32 events; PP2A-mediated dephosphorylation of key metabolic factors; ERKs are inactivated"	"44"	"0"	"54.5"	"56.6"	"52.5"	"66.7"	"51.3"	"47.8"	"84.3"	"83.1"	"102.9"	"203.5"	"265.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3B7T1"	"Erythroid differentiation-related factor 1 OS=Homo sapiens OX=9606 GN=EDRF1 PE=1 SV=1"	"0.000"	""	"3"	"3"	"6"	"3"	"1238"	"138.4"	"6.33"	"769.14"	"7.79"	"3"	"3"	"other biological processes"	"nucleus"	""	""	"26098"	"ENSG00000107938"	"EDRF1"	"B2RC65; hsa:26098; Q3B7T1; Q3KR40; Q4G190; Q5VZQ4; Q8IZ74; Q9Y3W4"	""	""	"0"	"0"	"4.0"	"2.7"	"2.7"	"4.6"	"5.2"	"2.1"	"7.8"	"15.0"	"30.1"	"115.5"	"176.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRR8"	"G patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GPATCH1 PE=1 SV=1"	"0.000"	""	"7"	"3"	"3"	"3"	"931"	"103.3"	"7.05"	"413.89"	"7.78"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf01585, Pf07713"	"55094"	"ENSG00000076650"	"GPATCH1"	"hsa:55094; Q8IZV6; Q8N3B7; Q9BRR8; Q9NW94"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"19.6"	"19.1"	"28.7"	"32.0"	"29.2"	"25.8"	"48.4"	"55.5"	"96.9"	"252.5"	"342.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTL3"	"RNA guanine-N7 methyltransferase activating subunit OS=Homo sapiens OX=9606 GN=RAMAC PE=1 SV=1"	"0.000"	""	"19"	"2"	"4"	"2"	"118"	"14.4"	"8.94"	"902.17"	"7.78"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf15320"	"83640"	"ENSG00000169612"	"RAMAC"	"hsa:83640; Q2M1J8; Q9BTL3"	"15q25 copy number variation"	""	"1"	"0"	"172.2"	"151.5"	"184.6"	"211.1"	"174.1"	"170.1"	"223.4"	"246.5"	"286.1"	"532.4"	"712.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35250"	"Replication factor C subunit 2 OS=Homo sapiens OX=9606 GN=RFC2 PE=1 SV=3"	"0.000"	""	"9"	"2"	"4"	"2"	"354"	"39.1"	"6.44"	"848.31"	"7.77"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004, Pf08542"	"5982"	"ENSG00000049541"	"RFC2"	"B5BU07; D3DXG3; hsa:5982; P32846; P35250; Q9BU93"	"DNA replication; Nucleotide excision repair; 7q11.23 copy number variation syndrome; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Homologous Recombination (HRR); HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Dual incision in TC-NER; Dual Incision in GG-NER; Activation of ATR in response to replication stress; Termination of translesion DNA synthesis; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"27"	"0"	"37.0"	"38.8"	"45.1"	"58.2"	"42.3"	"34.9"	"66.8"	"78.6"	"117.9"	"235.2"	"322.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PFW1"	"Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 1 OS=Homo sapiens OX=9606 GN=PPIP5K1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"1"	"1433"	"159.4"	"5.40"	"847.66"	"7.76"	"2"	"2"	"other metabolic processes"	"plasma membrane;other membranes;cytosol"	"kinase activity;other molecular function"	"Pf00328, Pf18086"	"9677"	"ENSG00000168781"	"PPIP5K1"	"hsa:9677; O15082; Q5HYF8; Q6PFW1; Q7Z3A7; Q86TE7; Q86UV3; Q86UV4; Q86XW8; Q8IZN0"	""	"Synthesis of pyrophosphates in the cytosol"	"1"	"0"	"4.2"	"3.7"	"3.1"	"3.7"	"3.1"	"4.3"	"11.5"	"12.3"	"24.2"	"60.0"	"80.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZW49"	"PAX-interacting protein 1 OS=Homo sapiens OX=9606 GN=PAXIP1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1069"	"121.3"	"6.70"	"892.70"	"7.76"	"2"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00533, Pf12738"	"22976"	"ENSG00000157212"	"PAXIP1"	"hsa:22976; O15404; Q6N099; Q6ZW49; Q6ZWH9; Q7Z315; Q86UN0; Q8N4P9; Q96HP2"	"16p11.2 proximal deletion syndrome; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Kleefstra syndrome"	"Nonhomologous End-Joining (NHEJ); Activation of anterior HOX genes in hindbrain development during early embryogenesis; Formation of WDR5-containing histone-modifying complexes"	"6"	"0"	"24.6"	"29.0"	"25.4"	"35.5"	"27.0"	"19.5"	"33.0"	"34.2"	"41.1"	"68.3"	"79.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPT8"	"Zinc finger CCCH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=ZC3H4 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"1303"	"140.2"	"6.27"	"287.70"	"7.75"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608, Pf18044"	"23211"	"ENSG00000130749"	"ZC3H4"	"hsa:23211; Q9UPT8; Q9Y420"	""	""	"0"	"0"	"33.3"	"48.6"	"39.9"	"51.3"	"38.0"	"48.5"	"51.4"	"60.1"	"87.6"	"158.6"	"230.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y285"	"Phenylalanine--tRNA ligase alpha subunit OS=Homo sapiens OX=9606 GN=FARSA PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"508"	"57.5"	"7.80"	"831.01"	"7.73"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf18552, Pf18553, Pf18554"	"2193"	"ENSG00000179115"	"FARSA"	"B4E363; hsa:2193; Q9NSD8; Q9Y285; Q9Y4W8"	""	"Cytosolic tRNA aminoacylation"	"1"	"0"	"170.3"	"183.9"	"179.4"	"193.2"	"167.8"	"190.4"	"246.1"	"243.8"	"287.7"	"568.8"	"746.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q09161"	"Nuclear cap-binding protein subunit 1 OS=Homo sapiens OX=9606 GN=NCBP1 PE=1 SV=1"	"0.000"	""	"5"	"3"	"6"	"3"	"790"	"91.8"	"6.43"	"1636.81"	"7.72"	"3"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02854, Pf09088, Pf09090"	"4686"	"ENSG00000136937"	"NCBP1"	"B2R718; hsa:4686; Q09161; Q59G76; Q5T1V0; Q5T7X2"	"mRNA processing; 3q29 copy number variation syndrome"	"mRNA Splicing - Major Pathway; mRNA 3'-end processing; RNA Polymerase II Transcription Termination; RNA polymerase II transcribes snRNA genes; Processing of Intronless Pre-mRNAs; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; snRNP Assembly; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Abortive elongation of HIV-1 transcript in the absence of Tat; RNA Polymerase II Pre-transcription Events; mRNA Capping; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Signaling by FGFR2 IIIa TM; SLBP independent Processing of Histone Pre-mRNAs; SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs"	"29"	"0"	"142.1"	"133.1"	"170.9"	"217.8"	"137.5"	"139.9"	"240.5"	"259.6"	"345.3"	"782.9"	"1181.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14669"	"E3 ubiquitin-protein ligase TRIP12 OS=Homo sapiens OX=9606 GN=TRIP12 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1992"	"220.3"	"8.48"	"340.89"	"7.70"	"1"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00632"	"9320"	"ENSG00000153827"	"TRIP12"	"D4HL82; hsa:9320; Q14669; Q14CA3; Q14CF1; Q15644; Q53R87; Q53TE7"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"18.9"	"13.9"	"32.9"	"43.8"	"25.7"	"18.3"	"37.6"	"38.1"	"56.7"	"112.7"	"173.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCC0"	"Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial OS=Homo sapiens OX=9606 GN=MCCC2 PE=1 SV=1"	"0.000"	""	"8"	"4"	"7"	"4"	"563"	"61.3"	"7.68"	"1350.85"	"7.69"	"4"	"3"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01039"	"64087"	"ENSG00000131844"	"MCCC2"	"A6NIY9; hsa:64087; Q96C27; Q9HCC0; Q9Y4L7"	""	"Biotin transport and metabolism; Branched-chain amino acid catabolism; Defective HLCS causes multiple carboxylase deficiency"	"3"	"0"	"398.2"	"491.4"	"326.1"	"467.5"	"331.9"	"349.8"	"538.0"	"576.9"	"623.6"	"1088.1"	"1293.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD6"	"39S ribosomal protein L1, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL1 PE=1 SV=2"	"0.000"	""	"16"	"4"	"5"	"4"	"325"	"36.9"	"8.78"	"1164.85"	"7.68"	"3"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00687"	"65008"	"ENSG00000169288"	"MRPL1"	"A6NG03; hsa:65008; Q4W5B8; Q6IAG4; Q96BW3; Q9BYD6; Q9H793; Q9NRL5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"207.0"	"175.9"	"242.9"	"313.2"	"198.2"	"228.5"	"828.6"	"942.1"	"1584.4"	"2230.9"	"2435.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52294"	"Importin subunit alpha-5 OS=Homo sapiens OX=9606 GN=KPNA1 PE=1 SV=3"	"0.000"	""	"8"	"3"	"5"	"1"	"538"	"60.2"	"5.01"	"958.23"	"7.68"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;transport;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"3836"	"ENSG00000114030"	"KPNA1"	"D3DN93; hsa:3836; P52294; Q6IBQ9; Q9BQ56"	"Ebola virus infection in host"	"ISG15 antiviral mechanism; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Vpr-mediated nuclear import of PICs; Apoptosis induced DNA fragmentation; Interferon alpha/beta signaling; Assembly of the ORC complex at the origin of replication; Integration of provirus; Inhibition of nitric oxide production"	"10"	"0"	"3.7"	"0.0"	"3.9"	"9.4"	"5.2"	"5.8"	"9.2"	"11.9"	"19.2"	"51.9"	"67.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T2T1"	"MAGUK p55 subfamily member 7 OS=Homo sapiens OX=9606 GN=MPP7 PE=1 SV=1"	"0.000"	""	"11"	"4"	"6"	"4"	"576"	"65.5"	"7.14"	"1575.24"	"7.67"	"4"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00595, Pf00625, Pf02828"	"143098"	"ENSG00000150054"	"MPP7"	"B2RCC9; B4DWL9; B5MDZ3; D3DRW3; hsa:143098; Q5T2T0; Q5T2T1; Q8IY28"	""	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RHOJ GTPase cycle"	"6"	"0"	"52.3"	"52.9"	"73.2"	"83.5"	"58.6"	"53.6"	"122.5"	"126.9"	"221.9"	"410.7"	"443.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H845"	"Complex I assembly factor ACAD9, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD9 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"621"	"68.7"	"7.96"	"412.87"	"7.66"	"1"	"2"	"cell organization and biogenesis;other metabolic processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"28976"	"ENSG00000177646"	"ACAD9"	"D3DNB8; hsa:28976; Q8WXX3; Q9H845"	"Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"Complex I biogenesis"	"3"	"0"	"13.4"	"10.1"	"15.7"	"13.1"	"10.8"	"11.1"	"20.0"	"20.8"	"40.9"	"86.9"	"114.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8H0"	"Nucleolar protein 11 OS=Homo sapiens OX=9606 GN=NOL11 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"719"	"81.1"	"6.07"	"776.59"	"7.65"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf08168"	"25926"	"ENSG00000130935"	"NOL11"	"B7Z5V9; hsa:25926; Q7L5S1; Q9H8H0; Q9UG18"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"26.0"	"21.9"	"29.1"	"26.5"	"24.7"	"19.6"	"46.7"	"49.3"	"56.5"	"147.6"	"207.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60684"	"Importin subunit alpha-7 OS=Homo sapiens OX=9606 GN=KPNA6 PE=1 SV=1"	"0.000"	""	"4"	"3"	"6"	"1"	"536"	"60.0"	"4.98"	"1317.10"	"7.64"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00514, Pf01749, Pf16186"	"23633"	"ENSG00000025800"	"KPNA6"	"B2RDC7; D3DPP5; hsa:23633; O60684; Q5VVU3"	""	"Assembly of the ORC complex at the origin of replication"	"1"	"1"	"244.9"	"231.2"	"264.3"	"328.6"	"217.2"	"261.7"	"423.8"	"421.6"	"669.2"	"2288.1"	"3588.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q1L5Z9"	"LON peptidase N-terminal domain and RING finger protein 2 OS=Homo sapiens OX=9606 GN=LONRF2 PE=2 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"754"	"83.6"	"5.90"	"532.41"	"7.64"	"1"	"2"	""	"other cell component"	"other molecular function"	"Pf02190, Pf13923"	"164832"	"ENSG00000170500"	"LONRF2"	"B9A006; hsa:164832; Q1L5Z9; Q6ZSR4"	""	""	"0"	"0"	"20.1"	"22.1"	"19.5"	"27.9"	"21.4"	"24.0"	"45.0"	"47.9"	"108.5"	"279.1"	"394.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00403"	"Cytochrome c oxidase subunit 2 OS=Homo sapiens OX=9606 GN=MT-CO2 PE=1 SV=1"	"0.000"	""	"12"	"2"	"3"	"2"	"227"	"25.5"	"4.82"	"508.89"	"7.63"	"1"	"2"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00116, Pf02790"	"4513"	"ENSG00000198712"	"MT-CO2"	"hsa:4513; P00403; Q37526"	"Electron transport chain: OXPHOS system in mitochondria; Endothelin pathways; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Neuroinflammation; Mitochondrial complex IV assembly; CCL18 signaling pathway; 5q35 copy number variation"	"Cytoprotection by HMOX1; Respiratory electron transport; TP53 Regulates Metabolic Genes"	"11"	"0"	"28.1"	"24.8"	"26.8"	"44.8"	"28.2"	"21.9"	"56.2"	"59.5"	"106.0"	"371.5"	"534.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FJ2"	"Dynein light chain 2, cytoplasmic OS=Homo sapiens OX=9606 GN=DYNLL2 PE=1 SV=1"	"0.000"	""	"46"	"3"	"4"	"2"	"89"	"10.3"	"7.37"	"720.74"	"7.61"	"2"	"2"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01221"	"140735"	"ENSG00000264364"	"DYNLL2"	"B2R5B4; hsa:140735; Q96FJ2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"Separation of Sister Chromatids; MHC class II antigen presentation; Aggrephagy; HCMV Early Events; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; COPI-mediated anterograde transport; Intraflagellar transport; COPI-independent Golgi-to-ER retrograde traffic; Macroautophagy; Activation of BMF and translocation to mitochondria"	"18"	"0"	"106.6"	"118.5"	"140.6"	"150.5"	"138.5"	"136.8"	"208.7"	"214.6"	"259.6"	"404.5"	"479.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6WCQ1"	"Myosin phosphatase Rho-interacting protein OS=Homo sapiens OX=9606 GN=MPRIP PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"1025"	"116.5"	"6.21"	"454.66"	"7.61"	"1"	"2"	""	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf00169"	"23164"	"ENSG00000133030"	"MPRIP"	"hsa:23164; Q3KQZ5; Q5FB94; Q6DHW2; Q6WCQ1; Q7Z5Y2; Q8N390; Q96G40"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"113.6"	"84.1"	"123.1"	"130.1"	"103.1"	"65.9"	"125.3"	"136.6"	"150.6"	"211.0"	"232.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Q9"	"General transcription factor 3C polypeptide 3 OS=Homo sapiens OX=9606 GN=GTF3C3 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"886"	"101.2"	"5.07"	"674.24"	"7.60"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13181"	"9330"	"ENSG00000119041"	"GTF3C3"	"hsa:9330; Q4ZG48; Q86XJ8; Q8WX84; Q96B44; Q9H5I8; Q9NT97; Q9Y5Q9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"68.5"	"49.9"	"66.3"	"73.0"	"64.4"	"59.5"	"96.2"	"97.8"	"122.2"	"348.5"	"560.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92558"	"Wiskott-Aldrich syndrome protein family member 1 OS=Homo sapiens OX=9606 GN=WASF1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"559"	"61.6"	"6.46"	"705.79"	"7.59"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02205"	"8936"	"ENSG00000112290"	"WASF1"	"E1P5F2; hsa:8936; Q5SZK7; Q92558"	"VEGFA-VEGFR2 signaling; Regulation of actin cytoskeleton"	"VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RAC1 GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC3 GTPase cycle"	"8"	"0"	"70.1"	"61.6"	"82.2"	"101.0"	"71.0"	"85.6"	"137.1"	"137.8"	"214.4"	"340.4"	"413.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14558"	"Phosphoribosyl pyrophosphate synthase-associated protein 1 OS=Homo sapiens OX=9606 GN=PRPSAP1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"1"	"356"	"39.4"	"7.20"	"814.71"	"7.58"	"2"	"2"	"other metabolic processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf13793, Pf14572"	"5635"	"ENSG00000161542"	"PRPSAP1"	"B2R6M4; hsa:5635; Q14558; Q96H06"	""	""	"0"	"0"	"27.1"	"17.6"	"25.1"	"39.2"	"27.2"	"22.4"	"58.7"	"66.1"	"102.0"	"208.6"	"311.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P2R7"	"Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial OS=Homo sapiens OX=9606 GN=SUCLA2 PE=1 SV=3"	""	""	"3"	"2"	"3"	"2"	"463"	"50.3"	"7.42"	""	"7.56"	""	"2"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00549, Pf08442"	"8803"	"ENSG00000136143"	"SUCLA2"	"B2RDE7; hsa:8803; O95194; Q5T9Q4; Q5T9Q6; Q9NV21; Q9NVP7; Q9P2R7"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"83.5"	"66.8"	"107.4"	"127.8"	"86.6"	"72.7"	"179.2"	"185.6"	"233.7"	"1732.9"	"4032.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBF2"	"Coatomer subunit gamma-2 OS=Homo sapiens OX=9606 GN=COPG2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"1"	"871"	"97.6"	"5.81"	"771.22"	"7.55"	"2"	"2"	"transport"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01602, Pf08752, Pf16381"	"26958"	"ENSG00000158623"	"COPG2"	"A6NH74; hsa:26958; Q2NLA0; Q54AC3; Q8WVW8; Q9UBF2"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46783"	"40S ribosomal protein S10 OS=Homo sapiens OX=9606 GN=RPS10 PE=1 SV=1"	"0.000"	""	"28"	"4"	"11"	"3"	"165"	"18.9"	"10.15"	"3370.70"	"7.54"	"4"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf03501"	"6204"	"ENSG00000124614"	"RPS10"	"B2R4E3; hsa:6204; P46783; Q5TZC0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"870.2"	"1165.5"	"965.3"	"1015.0"	"863.9"	"795.8"	"985.7"	"1024.9"	"1051.4"	"1390.8"	"1471.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00429"	"Dynamin-1-like protein OS=Homo sapiens OX=9606 GN=DNM1L PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"736"	"81.8"	"6.81"	""	"7.54"	""	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00350, Pf01031, Pf02212"	"10059"	"ENSG00000087470"	"DNM1L"	"A8K4X9; B4DGC9; B4DSU8; G8JLD5; hsa:10059; J3KPI2; O00429; O14541; O60709; Q59GN9; Q7L6B3; Q8TBT7; Q9BWM1; Q9Y5J2"	"Synaptic vesicle pathway; CAMKK2 pathway"	"Apoptotic execution phase"	"3"	"0"	"0.0"	"2.9"	"3.9"	"5.6"	"3.9"	"4.0"	"8.5"	"5.9"	"11.1"	"93.9"	"168.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13861"	"cAMP-dependent protein kinase type II-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR2A PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"404"	"45.5"	"5.07"	"499.66"	"7.53"	"2"	"3"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5576"	"ENSG00000114302"	"PRKAR2A"	"hsa:5576; P13861; Q16823; Q9BUB1"	"Myometrial relaxation and contraction pathways; G protein signaling pathways; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; GDNF signaling; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"GPER1 signaling; FCGR3A-mediated IL10 synthesis; ADORA2B mediated anti-inflammatory cytokines production; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase; ROBO receptors bind AKAP5"	"20"	"0"	"128.5"	"110.3"	"130.3"	"158.2"	"120.6"	"95.2"	"233.6"	"241.5"	"307.3"	"867.3"	"1386.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q53GQ0"	"Very-long-chain 3-oxoacyl-CoA reductase OS=Homo sapiens OX=9606 GN=HSD17B12 PE=1 SV=2"	""	""	"7"	"2"	"2"	"2"	"312"	"34.3"	"9.32"	""	"7.52"	""	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"extracellular matrix;other membranes;ER/Golgi"	"other molecular function"	"Pf00106"	"51144"	"ENSG00000149084"	"HSD17B12"	"A8K9B0; D3DR23; hsa:51144; Q53GQ0; Q96EA9; Q96JU2; Q9Y6G8"	"Mitochondrial fatty acid synthesis pathway"	"Synthesis of very long-chain fatty acyl-CoAs; Androgen biosynthesis"	"3"	"0"	"88.4"	"73.9"	"108.0"	"116.0"	"92.2"	"91.8"	"207.0"	"219.7"	"393.6"	"982.4"	"1273.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P158"	"Putative ATP-dependent RNA helicase DHX57 OS=Homo sapiens OX=9606 GN=DHX57 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"1"	"1386"	"155.5"	"7.71"	"803.34"	"7.51"	"2"	"2"	""	""	"other molecular function"	"Pf00270, Pf00271, Pf04408, Pf05773, Pf07717, Pf18044"	"90957"	"ENSG00000163214"	"DHX57"	"A2RRC7; hsa:90957; Q53SI4; Q6P158; Q6P9G1; Q7Z6H3; Q8NG17; Q96M33"	""	""	"0"	"0"	"0.0"	"3.5"	"2.5"	"3.2"	"2.3"	"0.0"	"6.6"	"8.7"	"15.3"	"34.9"	"49.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TV6"	"Tetratricopeptide repeat protein 7B OS=Homo sapiens OX=9606 GN=TTC7B PE=1 SV=3"	"0.000"	""	"2"	"1"	"4"	"1"	"843"	"94.1"	"6.89"	"903.86"	"7.51"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	"Pf12895, Pf13181, Pf13424, Pf19440"	"145567"	"ENSG00000165914"	"TTC7B"	"hsa:145567; Q86TV6; Q86U24; Q86VT3"	""	""	"0"	"0"	"35.4"	"34.4"	"63.6"	"44.7"	"28.9"	"27.4"	"73.8"	"87.0"	"157.6"	"370.5"	"486.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR56"	"Muscleblind-like protein 1 OS=Homo sapiens OX=9606 GN=MBNL1 PE=1 SV=2"	"0.001"	""	"7"	"2"	"3"	"2"	"388"	"41.8"	"8.90"	"246.03"	"7.49"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf14608"	"4154"	"ENSG00000152601"	"MBNL1"	"E9PBW7; hsa:4154; O43311; O43797; Q86UV8; Q86UV9; Q96P92; Q96RE3; Q9NR56"	"Adipogenesis"	""	"1"	"0"	"261.0"	"269.0"	"345.1"	"380.1"	"288.7"	"218.0"	"441.7"	"444.4"	"515.7"	"988.8"	"1397.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWH5"	"Probable tRNA pseudouridine synthase 1 OS=Homo sapiens OX=9606 GN=TRUB1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"349"	"37.2"	"8.25"	"765.87"	"7.49"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01509"	"142940"	"ENSG00000165832"	"TRUB1"	"B2R716; hsa:142940; Q53ES2; Q8WWH5"	""	""	"0"	"0"	"31.4"	"27.7"	"38.6"	"44.4"	"29.6"	"32.6"	"75.5"	"74.5"	"120.0"	"359.5"	"592.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18848"	"Cyclic AMP-dependent transcription factor ATF-4 OS=Homo sapiens OX=9606 GN=ATF4 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"2"	"351"	"38.6"	"4.96"	"835.21"	"7.47"	"2"	"2"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"468"	"ENSG00000128272"	"ATF4"	"hsa:468; P18848; Q96AQ3; Q9UH31"	"Alzheimer's disease and miRNA effects; Myometrial relaxation and contraction pathways; Photodynamic therapy-induced unfolded protein response; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; mRNA, protein, and metabolite inducation pathway by cyclosporin A; PI3K-Akt signaling pathway; Nonalcoholic fatty liver disease; Joubert syndrome; Hepatitis B infection; Unfolded protein response; 7q11.23 copy number variation syndrome; Alzheimer's disease"	"NFE2L2 regulating anti-oxidant/detoxification enzymes; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency; ATF6 (ATF6-alpha) activates chaperone genes"	"20"	"0"	"280.6"	"279.4"	"238.2"	"290.2"	"227.0"	"197.2"	"308.3"	"294.0"	"343.2"	"494.6"	"484.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96B36"	"Proline-rich AKT1 substrate 1 OS=Homo sapiens OX=9606 GN=AKT1S1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"4"	"1"	"256"	"27.4"	"4.75"	"691.12"	"7.46"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15798"	"84335"	"ENSG00000204673"	"AKT1S1"	"A8MTQ1; B2RE93; hsa:84335; J3KPM3; Q96B36; Q96BI4; Q96IK7; Q96NG2; Q9BWR5"	"Target of rapamycin signaling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; Thermogenesis; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Thyroid hormones production and peripheral downstream signaling effects; Autophagy; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells"	"HSF1-dependent transactivation; Constitutive Signaling by AKT1 E17K in Cancer; mTORC1-mediated signalling; AKT phosphorylates targets in the cytosol"	"21"	"0"	"147.2"	"123.4"	"153.7"	"171.5"	"120.6"	"127.6"	"190.0"	"185.2"	"194.3"	"320.0"	"416.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43324"	"Eukaryotic translation elongation factor 1 epsilon-1 OS=Homo sapiens OX=9606 GN=EEF1E1 PE=1 SV=1"	"0.000"	""	"12"	"2"	"4"	"2"	"174"	"19.8"	"8.54"	"677.79"	"7.46"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00043"	"9521"	"ENSG00000124802"	"EEF1E1"	"C9JLK5; hsa:9521; O43324; Q5THS2"	""	"Selenoamino acid metabolism; Cytosolic tRNA aminoacylation"	"2"	"0"	"61.3"	"48.7"	"67.9"	"81.4"	"59.6"	"59.6"	"106.9"	"118.7"	"169.0"	"658.9"	"916.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47755"	"F-actin-capping protein subunit alpha-2 OS=Homo sapiens OX=9606 GN=CAPZA2 PE=1 SV=3"	"0.000"	""	"13"	"2"	"4"	"2"	"286"	"32.9"	"5.85"	"801.24"	"7.40"	"2"	"2"	"cell organization and biogenesis"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01267"	"830"	"ENSG00000198898"	"CAPZA2"	"B4DG50; hsa:830; P47755"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Sensory processing of sound by inner hair cells of the cochlea; Factors involved in megakaryocyte development and platelet production; Advanced glycosylation endproduct receptor signaling"	"7"	"0"	"16.1"	"8.5"	"18.1"	"22.2"	"20.1"	"15.6"	"22.7"	"32.8"	"37.7"	"110.2"	"191.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27635"	"60S ribosomal protein L10 OS=Homo sapiens OX=9606 GN=RPL10 PE=1 SV=4"	"0.000"	""	"11"	"2"	"4"	"2"	"214"	"24.6"	"10.08"	"806.20"	"7.40"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00252"	"100137264; 100146244; 100172946; 100415355; 100468790; 100724614; 100982236; 101083663; 101136536; 101344695; 101444008; 101539056; 101690567; 101867181; 101975002; 102028809; 102257301; 102442647; 102878669; 102890423; 102923570; 102957760; 103127392; 103211225; 103250904; 103731218; 104667036; 104872587; 105294701; 105302495; 105467951; 105521640; 105579731; 105727260; 105824536; 105867804; 106000161; 107160308; 108513162; 108518769; 109696857; 110954; 465944; 700795; 81764"	"ENSAMEG00000000227; ENSANAG00000036053; ENSCAFG00020009114; ENSCAFG00030015144; ENSCAFG00040021422; ENSCAFG00845028627; ENSCANG00000032226; ENSCATG00000030970; ENSCCAG00000024992; ENSCGRG00001008387; ENSCJAG00000011822; ENSCLAG00000003108; ENSCPOG00000002355; ENSECAG00000017154; ENSFCAG00000011395; ENSGGOG00000000131; ENSLCNG00005021252; ENSMFAG00000040824; ENSMLUG00000014337; ENSMMMG00000014279; ENSMMUG00000005494; ENSMNEG00000038094; ENSMPUG00000009320; ENSMUSG00000008682; ENSMUSG00000058443; ENSNGAG00000023746; ENSNLEG00000028143; ENSNVIG00000023818; ENSPANG00000008309; ENSPCOG00000027122; ENSPPAG00000034160; ENSPPYG00000020874; ENSPSMG00000015404; ENSPTIG00000005599; ENSPTRG00000043378; ENSRBIG00000042996; ENSRNOG00000056765; ENSRROG00000019247; ENSSSUG00005010590; ENSSTOG00000011857; ENSTGEG00000012563; ENSUAMG00000020454; ENSUMAG00000019583; ENSUPAG00010000252"	"LOC100768740; LOC101344695; LOC105294701; LOC112632580; Rpl10; RPL10"	"A0A091D943; A0A1S3APJ4; A0A1S3GPT7; A0A1U7SU42; A0A250YCK6; A0A286XQR8; A0A2I3FV08; A0A2J8IN69; A0A2J8RLU6; A0A2K5EV78; A0A2K5ILK8; A0A2K5LLF2; A0A2K5QER4; A0A2K5U275; A0A2K6D043; A0A2K6GRP4; A0A2K6MTH0; A0A2K6NK39; A0A2R9B361; A0A2Y9G5G6; A0A384DKX1; A0A3Q0CF07; A0A3Q7NJC4; A0A452S2Z9; A0A485PEW4; A0A667IJV2; A0A673U4F8; A0A6D2WIN2; A0A6D2XTB8; A0A6I9ME29; A0A6J0A9X4; A0A6J2E7G1; A0A6J3GU06; A0A6P3QFP2; A0A6P5P1X6; A0A6P6DLY1; A0A7J7YFN8; A0A7J8J7V5; A0A822A0T4; A0A8B7B976; A0A8B7FW91; A0A8C0K7J7; A0A8C0TBM4; A0A8C2LMI8; A0A8C2UVN1; A0A8C5ZPE8; A0A8C6S1T7; A0A8C7BXJ2; A0A8C8ZPD3; A0A8C9J452; A0A8D2F5T2; A0A8D2GF85; A0A8I3PXJ3; A0A8J8XDM4; A0A8M1M1S6; A0A9B0U593; A2AM97; A6KRS1; A9CB60; aju:106987320; aml:100468790; B0KWW6; B1MTV1; B3RFD9; C3PT02; cang:105521640; caty:105579731; ccan:109696857; cpoc:100724614; csyr:103250904; D3YC00; dnm:101444008; dord:106000161; ecb:100146244; F7AYR2; F7GKJ8; fca:101083663; G1PPT9; G2HFW2; G3S9Q9; G7Q3B3; ggo:101136536; H2PX84; I2CYS4; I3MI39; L5KDV0; L8Y8T7; M3WF14; M3YD39; mcal:110286529; mcc:700795; mcf:101867181; mlf:102442647; mmu:110954; mmur:105867804; mni:105467951; mpuf:101690567; myb:102257301; nsu:110578606; P45634; pale:102878669; pale:102890423; panu:100137264; pcoq:105824536; pps:100982236; ptg:102957760; ptr:465944; pvp:105294701; pvp:105302495; Q569M8; Q5M9K8; Q6PDV7; Q6ZWV3; rbb:108513162; rbb:108518769; rno:81764; rro:104667036; S7NR49; sara:101539056; tmu:101344695; umr:103679662; zca:113931110"	"Cytoplasmic ribosomal proteins"	"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; L13a-mediated translational silencing of Ceruloplasmin expression; SRP-dependent cotranslational protein targeting to membrane; Major pathway of rRNA processing in the nucleolus and cytosol; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"15"	"0"	"88.6"	"89.9"	"115.3"	"132.5"	"118.6"	"81.9"	"146.4"	"168.2"	"193.9"	"341.0"	"619.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIG0"	"Tyrosine-protein kinase BAZ1B OS=Homo sapiens OX=9606 GN=BAZ1B PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1483"	"170.8"	"8.48"	"804.42"	"7.40"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00439, Pf00628, Pf10537, Pf15612, Pf15613"	"9031"	"ENSG00000009954"	"BAZ1B"	"B9EGK3; D3DXE9; hsa:9031; O95039; O95247; O95277; Q6P1K4; Q86UJ6; Q9UIG0"	"IL-18 signaling pathway; 7q11.23 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks"	"5"	"0"	"53.0"	"50.9"	"64.4"	"70.8"	"51.9"	"60.0"	"105.4"	"101.4"	"177.2"	"344.9"	"379.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09132"	"Signal recognition particle 19 kDa protein OS=Homo sapiens OX=9606 GN=SRP19 PE=1 SV=3"	"0.000"	""	"19"	"2"	"4"	"2"	"144"	"16.1"	"9.85"	"664.39"	"7.39"	"2"	"2"	"cell organization and biogenesis;transport"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01922"	"6728"	"ENSG00000153037"	"SRP19"	"B2R4E9; D6RCQ5; hsa:6728; P09132; Q05D77; Q96FG6"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"83.9"	"55.9"	"118.6"	"112.2"	"80.8"	"72.5"	"129.6"	"117.2"	"161.8"	"312.5"	"624.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P000"	"COMM domain-containing protein 9 OS=Homo sapiens OX=9606 GN=COMMD9 PE=1 SV=2"	"0.000"	""	"11"	"2"	"4"	"2"	"198"	"21.8"	"5.88"	"705.85"	"7.39"	"2"	"2"	"transport;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf07258"	"29099"	"ENSG00000110442"	"COMMD9"	"E9PAN2; hsa:29099; Q96FI2; Q9H0R0; Q9P000"	""	"Neutrophil degranulation; Neddylation"	"2"	"0"	"32.1"	"29.2"	"35.8"	"36.0"	"32.1"	"25.8"	"54.2"	"53.7"	"66.8"	"238.0"	"492.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN7"	"Serine/threonine-protein phosphatase 6 regulatory subunit 1 OS=Homo sapiens OX=9606 GN=PPP6R1 PE=1 SV=5"	"0.000"	""	"3"	"2"	"4"	"2"	"881"	"96.7"	"4.55"	"702.85"	"7.37"	"2"	"2"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04499"	"22870"	"ENSG00000105063"	"PPP6R1"	"hsa:22870; Q2M2H3; Q504V2; Q6NVJ6; Q9BU97; Q9UPN7"	""	"COPII-mediated vesicle transport"	"1"	"0"	"75.4"	"52.4"	"67.7"	"71.9"	"67.3"	"69.3"	"95.6"	"97.2"	"123.4"	"211.2"	"293.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32929"	"Cystathionine gamma-lyase OS=Homo sapiens OX=9606 GN=CTH PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"405"	"44.5"	"6.70"	"640.04"	"7.37"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01053"	"1491"	"ENSG00000116761"	"CTH"	"B4E1R2; E9PDV0; hsa:1491; P32929; Q53FB3; Q53Y79; Q9H4W7; Q9H4W8"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Amino acid metabolism; Methionine metabolism leading to sulfur amino acids and related disorders; Ferroptosis"	"Degradation of cysteine and homocysteine; Metabolism of ingested SeMet, Sec, MeSec into H2Se; Cysteine formation from homocysteine"	"11"	"0"	"82.5"	"73.1"	"84.1"	"123.5"	"78.7"	"70.4"	"132.8"	"124.4"	"152.5"	"327.7"	"535.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17096"	"High mobility group protein HMG-I/HMG-Y OS=Homo sapiens OX=9606 GN=HMGA1 PE=1 SV=3"	"0.000"	""	"24"	"2"	"4"	"2"	"107"	"11.7"	"10.32"	"710.18"	"7.36"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	""	"3159"	"ENSG00000137309"	"HMGA1"	"hsa:3159; P10910; P17096; Q5T6U9; Q9UKB0"	"Adipogenesis; Pre-implantation embryo; Male infertility; 7q11.23 copy number variation syndrome; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Orexin receptor pathway"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"13"	"0"	"194.4"	"154.4"	"218.8"	"235.1"	"181.5"	"178.1"	"273.0"	"285.3"	"340.6"	"546.3"	"672.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60313"	"Dynamin-like 120 kDa protein, mitochondrial OS=Homo sapiens OX=9606 GN=OPA1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"960"	"111.6"	"7.87"	"705.16"	"7.35"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00350, Pf19434"	"4976"	"ENSG00000198836"	"OPA1"	"D3DNW4; E5KLJ5; E5KLJ6; E5KLJ7; E5KLK1; E5KLK2; hsa:4976; O60313"	"Orexin receptor pathway"	"Regulation of Apoptosis"	"2"	"0"	"38.9"	"31.8"	"49.2"	"65.4"	"33.6"	"40.7"	"73.7"	"79.9"	"112.6"	"340.6"	"547.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38432"	"Coilin OS=Homo sapiens OX=9606 GN=COIL PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"576"	"62.6"	"9.07"	"759.01"	"7.34"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15862"	"8161"	"ENSG00000121058"	"COIL"	"B2R931; hsa:8161; P38432"	""	""	"0"	"0"	"210.5"	"175.3"	"219.8"	"223.2"	"194.7"	"196.6"	"365.4"	"393.7"	"616.9"	"840.2"	"906.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5SVZ6"	"Zinc finger MYM-type protein 1 OS=Homo sapiens OX=9606 GN=ZMYM1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"5"	"2"	"1142"	"128.6"	"7.44"	"560.84"	"7.33"	"1"	"2"	""	"nucleus"	"other molecular function"	"Pf05699, Pf06467, Pf14291"	"79830"	"ENSG00000197056"	"ZMYM1"	"D3DPR7; hsa:79830; Q5SVZ6; Q7Z3Q4"	""	""	"0"	"0"	"209.9"	"163.5"	"205.5"	"204.9"	"159.1"	"206.2"	"254.1"	"266.4"	"317.3"	"948.1"	"1251.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15813"	"Tubulin-specific chaperone E OS=Homo sapiens OX=9606 GN=TBCE PE=1 SV=1"	""	""	"4"	"2"	"2"	"2"	"527"	"59.3"	"6.76"	""	"7.33"	""	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf14560"	"6905"	"ENSG00000282984; ENSG00000284770; ENSG00000285053"	"TBCE"	"A8K8C2; B7Z3P1; hsa:6905; Q15813"	""	"Post-chaperonin tubulin folding pathway"	"1"	"0"	"35.8"	"25.1"	"33.8"	"49.9"	"28.7"	"28.1"	"58.0"	"82.0"	"103.7"	"352.8"	"956.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBW8"	"COP9 signalosome complex subunit 7a OS=Homo sapiens OX=9606 GN=COPS7A PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"275"	"30.3"	"8.22"	"890.64"	"7.30"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf01399, Pf18392"	"50813"	"ENSG00000111652"	"COPS7A"	"A8K9A6; hsa:50813; Q9NVX3; Q9UBW8; Q9UJW4"	"Ciliary landscape"	"Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex; DNA Damage Recognition in GG-NER; Neddylation"	"5"	"0"	"21.3"	"16.0"	"26.4"	"23.8"	"15.9"	"24.4"	"51.7"	"69.8"	"92.4"	"271.0"	"463.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04899"	"Guanine nucleotide-binding protein G(i) subunit alpha-2 OS=Homo sapiens OX=9606 GN=GNAI2 PE=1 SV=3"	"0.000"	""	"8"	"2"	"4"	"1"	"355"	"40.4"	"5.54"	"798.94"	"7.29"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00503"	"2771"	"ENSG00000114353"	"GNAI2"	"B3KTZ0; B4DYA0; B4E2X5; hsa:2771; P04899; Q6B6N3; Q8IZ71"	"Thyroid stimulating hormone (TSH) signaling pathway; Corticotropin-releasing hormone signaling pathway; S1P receptor signal transduction; Complement system; G protein signaling pathways; Chemokine signaling pathway; Hippo signaling regulation pathways; Purinergic signaling; Opioid receptor pathways; Calcium regulation in cardiac cells; 5q35 copy number variation; Serotonin HTR1 group and FOS pathway"	"G alpha (i) signalling events; G alpha (z) signalling events; Adenylate cyclase inhibitory pathway; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Adrenaline,noradrenaline inhibits insulin secretion"	"22"	"0"	"17.5"	"12.8"	"23.5"	"25.8"	"22.0"	"22.9"	"30.6"	"42.3"	"68.0"	"163.5"	"225.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T7V8"	"RAB6-interacting golgin OS=Homo sapiens OX=9606 GN=GORAB PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"1"	"394"	"45.0"	"7.08"	"846.06"	"7.29"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"7.2"	"9.8"	"8.5"	"25.8"	"10.1"	"3.6"	"11.6"	"24.6"	"37.5"	"57.6"	"49.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2D4"	"Exocyst complex component 6B OS=Homo sapiens OX=9606 GN=EXOC6B PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"811"	"94.1"	"6.46"	"792.01"	"7.28"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport"	"other cell component"	""	"Pf04091"	"23233"	"ENSG00000144036"	"EXOC6B"	"B8ZZY3; hsa:23233; Q9Y2D4"	"Ciliary landscape"	""	"1"	"0"	"14.1"	"8.7"	"16.2"	"28.5"	"20.3"	"23.2"	"107.2"	"109.6"	"181.1"	"335.5"	"353.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5Z7"	"Host cell factor 2 OS=Homo sapiens OX=9606 GN=HCFC2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"792"	"86.7"	"8.48"	"790.07"	"7.28"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf13415"	"29915"	"ENSG00000111727"	"HCFC2"	"B2R8Q5; C0H5X3; hsa:29915; Q9Y5Z7"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"29.0"	"27.4"	"35.9"	"40.8"	"32.8"	"30.6"	"45.1"	"64.1"	"78.0"	"168.8"	"202.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI36"	"WD repeat-containing protein 36 OS=Homo sapiens OX=9606 GN=WDR36 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"951"	"105.3"	"7.53"	"658.41"	"7.28"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf04192, Pf12894"	"134430"	""	"WDR36"	"A2RUS4; hsa:134430; Q68E02; Q8N1Q2; Q8NI36"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"152.5"	"131.8"	"160.8"	"166.2"	"122.3"	"132.9"	"201.5"	"230.6"	"267.7"	"449.6"	"546.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60232"	"Protein ZNRD2 OS=Homo sapiens OX=9606 GN=ZNRD2 PE=1 SV=1"	""	""	"13"	"2"	"2"	"2"	"199"	"21.5"	"5.24"	""	"7.28"	""	"2"	"cell cycle OR cell proliferation;other biological processes"	""	""	"Pf06677"	"10534"	"ENSG00000173465"	"ZNRD2"	"hsa:10534; O60232"	""	""	"0"	"0"	"138.4"	"153.6"	"170.0"	"190.0"	"134.0"	"131.4"	"194.3"	"221.8"	"243.0"	"394.5"	"501.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6G9"	"Cytoplasmic dynein 1 light intermediate chain 1 OS=Homo sapiens OX=9606 GN=DYNC1LI1 PE=1 SV=3"	"0.000"	""	"4"	"2"	"4"	"2"	"523"	"56.5"	"6.42"	"672.97"	"7.27"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf05783"	"51143"	"ENSG00000144635"	"DYNC1LI1"	"A2RRG7; hsa:51143; Q53HC8; Q53HK7; Q9Y6G9"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; MHC class II antigen presentation; Neutrophil degranulation; HCMV Early Events; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Aggrephagy"	"15"	"0"	"70.2"	"62.4"	"80.1"	"89.8"	"75.1"	"75.4"	"102.9"	"109.6"	"144.6"	"398.8"	"603.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60645"	"Exocyst complex component 3 OS=Homo sapiens OX=9606 GN=EXOC3 PE=1 SV=3"	"0.000"	""	"3"	"2"	"5"	"2"	"745"	"85.5"	"6.29"	"1049.90"	"7.26"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06046"	"11336"	"ENSG00000180104"	"EXOC3"	"hsa:11336; O60645; Q6P2E8; Q8TEN6; Q8WUW0; Q96DI4"	"Ciliary landscape"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing; VxPx cargo-targeting to cilium"	"4"	"0"	"23.5"	"25.0"	"27.6"	"31.1"	"19.9"	"31.9"	"142.9"	"165.2"	"290.7"	"368.0"	"334.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00116"	"Alkyldihydroxyacetonephosphate synthase, peroxisomal OS=Homo sapiens OX=9606 GN=AGPS PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"658"	"72.9"	"7.34"	"847.22"	"7.26"	"2"	"2"	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01565, Pf02913"	"8540"	"ENSG00000018510"	"AGPS"	"A5D8U9; hsa:8540; O00116; Q2TU35"	"Triacylglyceride synthesis"	"Plasmalogen biosynthesis; TYSND1 cleaves peroxisomal proteins"	"4"	"0"	"60.9"	"62.9"	"64.3"	"61.5"	"53.9"	"55.7"	"89.3"	"93.4"	"142.2"	"214.7"	"274.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY42"	"Replication termination factor 2 OS=Homo sapiens OX=9606 GN=RTF2 PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"306"	"33.9"	"8.59"	"722.97"	"7.24"	"2"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04641"	"51507"	"ENSG00000022277"	"RTF2"	"E1P5Z9; hsa:51507; Q9BY42; Q9BYL7; Q9HCV9; Q9NX29; Q9NZZ8; Q9P002; Q9UHW3"	""	""	"0"	"0"	"55.7"	"40.8"	"63.5"	"62.6"	"60.2"	"67.6"	"140.7"	"169.9"	"226.7"	"400.8"	"588.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3Z3"	"Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 OS=Homo sapiens OX=9606 GN=SAMHD1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"626"	"72.2"	"7.14"	"912.40"	"7.24"	"3"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01966, Pf07647"	"25939"	"ENSG00000101347"	"SAMHD1"	"B4E2A5; E1P5V2; hsa:25939; Q5JXG8; Q8N491; Q9H004; Q9H005; Q9H3U9; Q9Y3Z3"	""	"Interferon alpha/beta signaling; Nucleotide catabolism"	"2"	"0"	"10.8"	"17.4"	"23.4"	"23.8"	"12.8"	"22.7"	"30.4"	"24.2"	"51.0"	"170.6"	"270.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02880"	"DNA topoisomerase 2-beta OS=Homo sapiens OX=9606 GN=TOP2B PE=1 SV=3"	"0.000"	""	"3"	"3"	"4"	"3"	"1626"	"183.2"	"8.00"	"540.86"	"7.24"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00204, Pf00521, Pf01751, Pf02518, Pf08070, Pf16898"	"7155"	"ENSG00000077097"	"TOP2B"	"hsa:7155; Q02880; Q13600; Q9UMG8; Q9UQP8"	""	"SUMOylation of DNA replication proteins"	"1"	"0"	"121.9"	"97.5"	"161.2"	"158.2"	"124.1"	"118.1"	"188.5"	"208.8"	"263.1"	"887.8"	"1878.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N488"	"RING1 and YY1-binding protein OS=Homo sapiens OX=9606 GN=RYBP PE=1 SV=2"	"0.000"	""	"13"	"2"	"3"	"2"	"228"	"24.8"	"9.63"	"308.22"	"7.24"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00641, Pf17219"	"23429"	"ENSG00000163602; ENSG00000281766"	"RYBP"	"hsa:23429; Q8N488; Q9P2W5; Q9UMW4"	""	"Transcriptional Regulation by E2F6; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"2"	"0"	"381.3"	"367.8"	"349.4"	"346.8"	"287.5"	"304.7"	"503.1"	"527.5"	"687.8"	"1113.6"	"1144.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A1X283"	"SH3 and PX domain-containing protein 2B OS=Homo sapiens OX=9606 GN=SH3PXD2B PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"911"	"101.5"	"8.69"	"269.42"	"7.23"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00787, Pf07653"	"285590"	"ENSG00000174705"	"SH3PXD2B"	"A1X283; B6F0V2; hsa:285590; Q9P2Q1"	""	""	"0"	"0"	"167.5"	"129.2"	"156.9"	"218.6"	"153.3"	"149.9"	"244.0"	"235.3"	"330.5"	"850.3"	"972.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PZ0"	"Pseudouridylate synthase 7 homolog OS=Homo sapiens OX=9606 GN=PUS7 PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"661"	"75.0"	"6.37"	"297.61"	"7.22"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01142"	"54517"	"ENSG00000091127"	"PUS7"	"hsa:54517; Q75MG4; Q96PZ0; Q9NX19"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"16.1"	"11.5"	"12.1"	"16.0"	"11.8"	"11.7"	"18.0"	"21.9"	"28.9"	"62.9"	"66.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14644"	"Ras GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=RASA3 PE=1 SV=3"	"0.000"	""	"4"	"2"	"4"	"2"	"834"	"95.6"	"7.15"	"692.30"	"7.20"	"2"	"2"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol"	"transporter activity;enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"22821"	"ENSG00000185989; ENSG00000280477"	"RASA3"	"A6NL15; F8W6X8; hsa:22821; Q14644; Q8IUY2"	"MAPK cascade; Ras signaling; IL-18 signaling pathway"	"Regulation of RAS by GAPs"	"4"	"0"	"27.2"	"20.6"	"26.4"	"40.2"	"24.2"	"22.1"	"65.6"	"80.3"	"123.6"	"170.4"	"170.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52434"	"DNA-directed RNA polymerases I, II, and III subunit RPABC3 OS=Homo sapiens OX=9606 GN=POLR2H PE=1 SV=4"	"0.000"	""	"25"	"3"	"5"	"3"	"150"	"17.1"	"4.68"	"1162.16"	"7.20"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03870"	"5437"	"ENSG00000163882"	"POLR2H"	"C9J413; C9JBJ6; C9JCU7; C9JUA8; hsa:5437; P52434; P53802; Q969R0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"Gap-filling DNA repair synthesis and ligation in TC-NER; mRNA Splicing - Major Pathway; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA polymerase II transcribes snRNA genes; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; Inhibition of DNA recombination at telomere"	"57"	"0"	"76.2"	"90.4"	"84.0"	"143.2"	"72.7"	"70.4"	"210.0"	"232.5"	"505.1"	"2790.6"	"3189.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNS1"	"Protein timeless homolog OS=Homo sapiens OX=9606 GN=TIMELESS PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1208"	"138.6"	"5.40"	"443.89"	"7.20"	"1"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04821, Pf05029"	"8914"	"ENSG00000111602"	"TIMELESS"	"B2ZAV0; hsa:8914; O94802; Q86VM1; Q8IWH3; Q9UNS1"	""	"Processing of DNA double-strand break ends"	"1"	"0"	"23.2"	"21.4"	"26.6"	"30.9"	"17.6"	"20.5"	"29.7"	"40.8"	"55.8"	"192.8"	"406.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15283"	"Ras GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=RASA2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"6"	"2"	"850"	"96.6"	"7.20"	"749.52"	"7.19"	"2"	"2"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00168, Pf00169, Pf00616, Pf00779"	"5922"	"ENSG00000155903"	"RASA2"	"A8K7K1; G3V0F9; hsa:5922; O00695; Q15283; Q15284; Q92594; Q99577; Q9UEQ2"	"MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Modulators of TCR signaling and T cell activation"	"Regulation of RAS by GAPs"	"5"	"0"	"88.9"	"84.1"	"93.5"	"110.4"	"96.2"	"117.6"	"282.3"	"293.4"	"325.3"	"460.8"	"580.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P013"	"Spliceosome-associated protein CWC15 homolog OS=Homo sapiens OX=9606 GN=CWC15 PE=1 SV=2"	"0.000"	""	"14"	"2"	"3"	"2"	"229"	"26.6"	"5.71"	"286.74"	"7.18"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04889"	"51503"	"ENSG00000150316"	"CWC15"	"B2RC17; hsa:51503; Q05BV9; Q05DM1; Q9P013; Q9UI29"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"92.7"	"106.6"	"116.1"	"127.0"	"76.2"	"91.0"	"133.1"	"152.5"	"196.4"	"688.1"	"1021.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09234"	"U1 small nuclear ribonucleoprotein C OS=Homo sapiens OX=9606 GN=SNRPC PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"159"	"17.4"	"9.67"	"793.22"	"7.17"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06220"	"6631"	"ENSG00000124562"	"SNRPC"	"hsa:6631; P09234; Q5TAL3"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"147.9"	"76.5"	"157.5"	"284.6"	"105.8"	"112.3"	"177.8"	"201.4"	"225.4"	"711.9"	"1129.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46087"	"Probable 28S rRNA (cytosine(4447)-C(5))-methyltransferase OS=Homo sapiens OX=9606 GN=NOP2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"812"	"89.2"	"9.23"	"692.75"	"7.17"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf01189, Pf08062, Pf17125"	"4839"	"ENSG00000111641"	"NOP2"	"A1A4Z3; B3KPD6; hsa:4839; P46087; Q05BA7; Q0P5S5; Q3KQS4; Q58F30"	"Imatinib and chronic myeloid leukemia"	"rRNA modification in the nucleus and cytosol; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"3"	"0"	"92.4"	"66.4"	"101.5"	"108.7"	"94.0"	"93.1"	"124.4"	"115.1"	"134.5"	"196.9"	"302.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB4"	"SRSF protein kinase 1 OS=Homo sapiens OX=9606 GN=SRPK1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"655"	"74.3"	"6.16"	"339.22"	"7.17"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"6732"	"ENSG00000096063"	"SRPK1"	"B4DS61; hsa:6732; Q12890; Q5R364; Q5R365; Q8IY12; Q96SB4"	"VEGFA-VEGFR2 signaling; mRNA processing"	"Maturation of nucleoprotein"	"3"	"0"	"103.5"	"78.5"	"119.0"	"141.8"	"108.5"	"115.1"	"141.3"	"144.9"	"182.0"	"370.7"	"600.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3U1"	"Protein unc-45 homolog A OS=Homo sapiens OX=9606 GN=UNC45A PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"944"	"103.0"	"6.07"	"814.38"	"7.16"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf11701, Pf13181, Pf13432"	"55898"	"ENSG00000140553"	"UNC45A"	"A8K6F7; hsa:55898; Q7L3Y6; Q9H3U1; Q9H3U8; Q9NSE8; Q9NSE9"	""	""	"0"	"0"	"9.7"	"11.8"	"12.8"	"16.6"	"13.6"	"15.9"	"43.4"	"48.5"	"64.3"	"204.1"	"322.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43301"	"Heat shock 70 kDa protein 12A OS=Homo sapiens OX=9606 GN=HSPA12A PE=1 SV=2"	""	""	"4"	"2"	"2"	"2"	"675"	"74.9"	"6.77"	""	"7.16"	""	"2"	""	"nucleus;other cell component"	"other molecular function"	""	"259217"	"ENSG00000165868"	"HSPA12A"	"hsa:259217; O43301"	""	"Regulation of HSF1-mediated heat shock response"	"1"	"0"	"43.7"	"50.5"	"67.1"	"44.6"	"41.6"	"36.8"	"61.2"	"86.6"	"114.0"	"210.1"	"259.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61970"	"Nuclear transport factor 2 OS=Homo sapiens OX=9606 GN=NUTF2 PE=1 SV=1"	"0.000"	""	"19"	"2"	"4"	"2"	"127"	"14.5"	"5.38"	"881.04"	"7.16"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf02136"	"10204"	"ENSG00000102898"	"NUTF2"	"B2R4G7; hsa:10204; P13662; P61970; Q6IB67"	""	""	"0"	"0"	"82.4"	"84.0"	"138.2"	"255.4"	"82.6"	"78.0"	"142.8"	"154.9"	"205.3"	"450.1"	"491.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99700"	"Ataxin-2 OS=Homo sapiens OX=9606 GN=ATXN2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1313"	"140.2"	"9.57"	"665.89"	"7.16"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity"	"Pf06741, Pf07145, Pf14438"	"6311"	"ENSG00000204842"	"ATXN2"	"A6NLD4; hsa:6311; Q24JQ7; Q6ZQZ7; Q99493; Q99700"	"Parkinson's disease pathway; EGF/EGFR signaling pathway"	""	"2"	"0"	"59.3"	"50.8"	"60.0"	"61.8"	"51.3"	"52.0"	"67.1"	"77.4"	"93.2"	"156.0"	"270.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52739"	"Zinc finger protein 131 OS=Homo sapiens OX=9606 GN=ZNF131 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"623"	"71.4"	"5.19"	"753.52"	"7.15"	"2"	"2"	"other biological processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00651, Pf12874"	"7690"	"ENSG00000172262"	"ZNF131"	"B4DRL3; hsa:7690; P52739; Q6PIF0"	""	"SUMOylation of transcription cofactors"	"1"	"0"	"19.3"	"14.2"	"23.1"	"17.7"	"18.0"	"15.2"	"31.8"	"39.5"	"68.4"	"193.6"	"232.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKS6"	"Protein kinase C and casein kinase substrate in neurons protein 3 OS=Homo sapiens OX=9606 GN=PACSIN3 PE=1 SV=2"	"0.000"	""	"8"	"3"	"5"	"3"	"424"	"48.5"	"6.18"	"1206.10"	"7.15"	"3"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00611, Pf14604"	"29763"	"ENSG00000165912"	"PACSIN3"	"A6NH84; hsa:29763; Q9H331; Q9NWV9; Q9UKS6"	""	"Clathrin-mediated endocytosis"	"1"	"0"	"162.2"	"140.3"	"184.2"	"206.0"	"145.2"	"164.1"	"292.2"	"294.0"	"401.6"	"1129.8"	"1482.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00186"	"Syntaxin-binding protein 3 OS=Homo sapiens OX=9606 GN=STXBP3 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"592"	"67.7"	"7.80"	"581.69"	"7.15"	"2"	"2"	"cell adhesion;cell-cell signaling;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00995"	"6814"	"ENSG00000116266"	"STXBP3"	"A8K269; A8K5K7; hsa:6814; O00186; Q53FW1; Q86YJ3; Q9UPD7"	"Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Disinhibition of SNARE formation"	"3"	"0"	"15.5"	"12.2"	"23.8"	"24.6"	"16.5"	"19.4"	"33.7"	"28.9"	"49.6"	"140.2"	"176.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4M9"	"EH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=EHD1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"534"	"60.6"	"6.83"	"689.12"	"7.15"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"10938"	"ENSG00000110047"	"EHD1"	"hsa:10938; O14611; Q2M3Q4; Q9H4M9; Q9UNR3"	"Insulin signaling"	"Factors involved in megakaryocyte development and platelet production"	"2"	"0"	"35.0"	"34.4"	"35.3"	"49.3"	"41.1"	"42.6"	"68.5"	"69.7"	"113.7"	"260.3"	"370.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRG1"	"Vacuolar protein-sorting-associated protein 25 OS=Homo sapiens OX=9606 GN=VPS25 PE=1 SV=1"	"0.000"	""	"28"	"4"	"6"	"4"	"176"	"20.7"	"6.34"	"2055.50"	"7.13"	"4"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05871"	"84313"	"ENSG00000131475"	"VPS25"	"B2R581; hsa:84313; Q9BRG1"	""	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"2"	"0"	"90.8"	"84.5"	"97.7"	"148.9"	"125.9"	"186.9"	"370.7"	"427.1"	"556.3"	"1083.9"	"1194.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16763"	"Ubiquitin-conjugating enzyme E2 S OS=Homo sapiens OX=9606 GN=UBE2S PE=1 SV=2"	"0.000"	""	"15"	"2"	"4"	"2"	"222"	"23.8"	"8.38"	"748.62"	"7.12"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"27338"	"ENSG00000108106"	"UBE2S"	"hsa:27338; Q16763; Q9BTC1"	""	"Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"19"	"0"	"3.4"	"9.2"	"7.7"	"12.0"	"5.1"	"4.8"	"21.7"	"27.6"	"58.7"	"175.6"	"108.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05086"	"Ubiquitin-protein ligase E3A OS=Homo sapiens OX=9606 GN=UBE3A PE=1 SV=4"	"0.000"	""	"2"	"1"	"3"	"1"	"875"	"100.6"	"5.22"	"522.91"	"7.12"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00632, Pf16558"	"7337"	"ENSG00000114062"	"UBE3A"	"A8K8Z9; hsa:7337; P78355; Q05086; Q93066; Q9UEP4; Q9UEP5; Q9UEP6; Q9UEP7; Q9UEP8; Q9UEP9"	"Androgen receptor signaling pathway; MECP2 and associated Rett syndrome; Prader-Willi and Angelman syndrome; Synaptic signaling pathways associated with autism spectrum disorder"	"Antigen processing: Ubiquitination & Proteasome degradation"	"5"	"0"	"43.7"	"36.0"	"58.4"	"75.1"	"47.5"	"55.4"	"98.5"	"97.7"	"145.2"	"356.7"	"650.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IV48"	"3'-5' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=ERI1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"4"	"2"	"349"	"40.0"	"6.70"	"639.30"	"7.11"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00929, Pf02037"	"90459"	"ENSG00000104626"	"ERI1"	"A8K4U7; hsa:90459; Q8IV48; Q9NSX3"	"exRNA mechanism of action and biogenesis; 8p23.1 copy number variation syndrome; 4p16.3 copy number variation"	"Major pathway of rRNA processing in the nucleolus and cytosol"	"4"	"0"	"102.8"	"91.9"	"119.7"	"137.2"	"116.5"	"122.9"	"300.1"	"328.0"	"676.8"	"1345.3"	"1134.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13200"	"26S proteasome non-ATPase regulatory subunit 2 OS=Homo sapiens OX=9606 GN=PSMD2 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"908"	"100.1"	"5.20"	"798.79"	"7.10"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01851, Pf17781, Pf18051"	"5708"	"ENSG00000175166"	"PSMD2"	"B4DX07; B4DXY1; E7EW34; E9PCS3; hsa:5708; Q12932; Q13200; Q15321; Q53XQ4; Q96I12"	"Proteasome degradation; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"ER-Phagosome pathway; Neutrophil degranulation; Ub-specific processing proteases; MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"63.1"	"49.9"	"65.4"	"72.1"	"54.7"	"54.2"	"93.9"	"98.9"	"117.4"	"302.4"	"504.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WUD4"	"Coiled-coil domain-containing protein 12 OS=Homo sapiens OX=9606 GN=CCDC12 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"166"	"19.2"	"7.34"	""	"7.10"	""	"1"	""	"nucleus"	""	"Pf08315"	"151903"	"ENSG00000160799"	"CCDC12"	"hsa:151903; Q8N8I4; Q8WUD4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"46.5"	"46.9"	"54.2"	"60.9"	"45.6"	"39.3"	"101.6"	"104.4"	"173.2"	"381.8"	"530.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15084"	"Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A OS=Homo sapiens OX=9606 GN=ANKRD28 PE=1 SV=5"	"0.000"	""	"3"	"2"	"4"	"2"	"1053"	"112.9"	"6.25"	"915.50"	"7.09"	"2"	"2"	""	"cytosol;nucleus"	""	"Pf00023, Pf13637"	"23243"	"ENSG00000206560"	"ANKRD28"	"B4DES5; hsa:23243; O15084; Q1WWL4; Q29RW6; Q3B857; Q6ULS0; Q6ZT57"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"12.8"	"10.0"	"18.0"	"21.3"	"14.2"	"13.1"	"29.2"	"27.2"	"32.5"	"92.1"	"143.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53680"	"AP-2 complex subunit sigma OS=Homo sapiens OX=9606 GN=AP2S1 PE=1 SV=2"	"0.000"	""	"15"	"2"	"4"	"2"	"142"	"17.0"	"6.18"	"677.86"	"7.09"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01217"	"1175"	"ENSG00000042753"	"AP2S1"	"B2R4Z4; hsa:1175; O75977; P53680; Q6PK67"	"Synaptic vesicle pathway; VEGFA-VEGFR2 signaling; GABA receptor signaling; EGF/EGFR signaling pathway; Fragile X syndrome"	"LDL clearance; Potential therapeutics for SARS; Recycling pathway of L1; MHC class II antigen presentation; Cargo recognition for clathrin-mediated endocytosis; WNT5A-dependent internalization of FZD4; EPH-ephrin mediated repulsion of cells; Nef Mediated CD4 Down-regulation; Retrograde neurotrophin signalling; Nef Mediated CD8 Down-regulation; WNT5A-dependent internalization of FZD2, FZD5 and ROR2; VLDLR internalisation and degradation"	"18"	"0"	"82.8"	"62.0"	"115.1"	"123.5"	"82.6"	"96.3"	"225.6"	"247.8"	"312.1"	"517.7"	"656.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHD1"	"Cysteine and histidine-rich domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHORDC1 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"2"	"332"	"37.5"	"7.87"	"429.61"	"7.08"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf04968, Pf04969"	"26973"	"ENSG00000110172; ENSG00000285023"	"CHORDC1"	"B2R6P8; hsa:26973; Q6IN49; Q8WVL9; Q9H3D6; Q9UHD1"	""	""	"0"	"0"	"31.7"	"28.1"	"45.5"	"48.3"	"33.6"	"43.7"	"59.8"	"65.8"	"82.5"	"597.1"	"1758.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBN7"	"Histone deacetylase 6 OS=Homo sapiens OX=9606 GN=HDAC6 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1215"	"131.3"	"5.30"	"731.94"	"7.08"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00850, Pf02148"	"10013"	"ENSG00000094631"	"HDAC6"	"hsa:10013; O94975; Q6NT75; Q7L3E5; Q96CY0; Q9UBN7"	"Neural crest differentiation; Ectoderm differentiation; Ectoderm differentiation; Ethanol effects on histone modifications; 7q11.23 copy number variation syndrome"	"Late endosomal microautophagy; Cilium Assembly; Aggrephagy; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Transcriptional regulation by RUNX2; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; RUNX2 regulates osteoblast differentiation; Chaperone Mediated Autophagy; HSF1 activation"	"16"	"0"	"97.4"	"60.7"	"82.6"	"96.1"	"81.5"	"77.8"	"101.8"	"100.9"	"111.1"	"144.5"	"167.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IX18"	"Probable ATP-dependent RNA helicase DHX40 OS=Homo sapiens OX=9606 GN=DHX40 PE=1 SV=2"	"0.000"	""	"6"	"4"	"5"	"4"	"779"	"88.5"	"8.65"	"1054.13"	"7.07"	"3"	"2"	""	""	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"79665"	"ENSG00000108406"	"DHX40"	"B3KTJ5; C9JR60; hsa:79665; Q5JPH4; Q8IX18; Q8TC86; Q8WY53; Q9BXM1; Q9H6M9"	""	""	"0"	"0"	"26.3"	"24.9"	"30.3"	"48.1"	"34.3"	"25.4"	"92.1"	"110.4"	"254.6"	"630.2"	"826.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L4I2"	"Arginine/serine-rich coiled-coil protein 2 OS=Homo sapiens OX=9606 GN=RSRC2 PE=1 SV=1"	"0.000"	""	"9"	"5"	"7"	"5"	"434"	"50.5"	"11.33"	"1612.88"	"7.06"	"5"	"2"	""	""	""	"Pf15477"	"65117"	"ENSG00000111011"	"RSRC2"	"hsa:65117; Q6N040; Q6NW16; Q7L4I2; Q9H864"	""	""	"0"	"0"	"780.3"	"595.4"	"754.0"	"782.7"	"606.5"	"641.1"	"909.3"	"946.3"	"1110.8"	"1921.3"	"2300.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWU1"	"3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial OS=Homo sapiens OX=9606 GN=OXSM PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"459"	"48.8"	"7.66"	"398.63"	"7.06"	"1"	"2"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00109, Pf02801"	"54995"	"ENSG00000151093"	"OXSM"	"hsa:54995; Q9NWU1"	"Mitochondrial fatty acid synthesis pathway"	""	"1"	"0"	"62.2"	"53.8"	"69.3"	"85.1"	"72.4"	"94.3"	"285.0"	"321.0"	"426.2"	"1084.0"	"1776.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15084"	"Protein disulfide-isomerase A6 OS=Homo sapiens OX=9606 GN=PDIA6 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"440"	"48.1"	"5.08"	"891.59"	"7.06"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"10130"	"ENSG00000143870"	"PDIA6"	"B3KY95; B5MCQ5; B7Z254; B7Z4M8; F8WA83; hsa:10130; Q15084; Q53RC7; Q6ZSH5; Q99778"	"Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; XBP1(S) activates chaperone genes"	"5"	"0"	"214.4"	"180.3"	"224.9"	"270.0"	"212.5"	"223.0"	"254.4"	"262.1"	"257.4"	"355.0"	"448.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHY1"	"Nuclear receptor-binding protein OS=Homo sapiens OX=9606 GN=NRBP1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"535"	"59.8"	"5.08"	"762.04"	"7.04"	"2"	"2"	"protein metabolism;other metabolic processes;transport"	"other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf07714"	"29959"	"ENSG00000115216"	"NRBP1"	"B3KV40; D6W558; hsa:29959; Q53FZ5; Q96SU3; Q9UHY1"	""	"Nuclear Receptor transcription pathway"	"1"	"0"	"31.3"	"31.3"	"37.5"	"45.6"	"29.9"	"23.1"	"47.4"	"54.0"	"59.1"	"121.8"	"143.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y388"	"RNA-binding motif protein, X-linked 2 OS=Homo sapiens OX=9606 GN=RBMX2 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"322"	"37.3"	"9.83"	"1036.59"	"7.01"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"other membranes;ER/Golgi;nucleus"	""	"Pf00076"	"51634"	"ENSG00000134597"	"RBMX2"	"A8K9Z0; hsa:51634; Q5JY82; Q9Y388; Q9Y3I8"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"126.5"	"114.2"	"129.0"	"161.5"	"110.0"	"132.4"	"176.3"	"178.1"	"209.5"	"376.7"	"460.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P81605"	"Dermcidin OS=Homo sapiens OX=9606 GN=DCD PE=1 SV=2"	"0.000"	""	"23"	"3"	"6"	"3"	"110"	"11.3"	"6.54"	"932.94"	"7.00"	"3"	"2"	"protein metabolism;stress response;transport;other biological processes"	"non-structural extracellular;other membranes"	"transporter activity;other molecular function"	"Pf15291"	"117159"	"ENSG00000161634"	"DCD"	"A5JHP2; A5JHP3; hsa:117159; P58461; P81605; Q53YJ2"	""	"Antimicrobial peptides"	"1"	"0"	"207.9"	"266.0"	"4865.4"	"185.3"	"211.2"	"163.2"	"313.2"	"322.7"	"427.8"	"507.0"	"680.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6W2J9"	"BCL-6 corepressor OS=Homo sapiens OX=9606 GN=BCOR PE=1 SV=1"	"0.000"	""	"1"	"2"	"4"	"2"	"1755"	"192.1"	"6.48"	"750.99"	"6.99"	"2"	"2"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf12796, Pf15808, Pf16553"	"54880"	"ENSG00000183337"	"BCOR"	"D3DWB3; D3DWB4; hsa:54880; Q29RF6; Q6P4B6; Q6W2J9; Q7Z2K7; Q8TEB4; Q96DB3; Q9H232; Q9H233; Q9HCJ7; Q9NXF2"	"Ectoderm differentiation; Pathways affected in adenoid cystic carcinoma; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma"	""	"3"	"0"	"75.5"	"57.1"	"82.7"	"76.2"	"61.4"	"78.8"	"94.7"	"86.0"	"107.7"	"192.6"	"195.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ52"	"Zinc phosphodiesterase ELAC protein 2 OS=Homo sapiens OX=9606 GN=ELAC2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"826"	"92.2"	"7.90"	"598.42"	"6.98"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf12706, Pf13691"	"60528"	"ENSG00000006744"	"ELAC2"	"B4DPL9; hsa:60528; Q6IA94; Q9BQ52; Q9HAS8; Q9HAS9; Q9NVT1"	""	"tRNA processing in the nucleus; tRNA processing in the mitochondrion; rRNA processing in the mitochondrion; tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis"	"4"	"0"	"24.0"	"24.0"	"34.3"	"41.2"	"28.0"	"34.8"	"69.0"	"81.1"	"113.9"	"365.9"	"573.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N1G0"	"Zinc finger protein 687 OS=Homo sapiens OX=9606 GN=ZNF687 PE=1 SV=1"	""	""	"3"	"2"	"2"	"2"	"1237"	"129.4"	"8.19"	""	"6.97"	""	"2"	""	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf16622"	"57592"	"ENSG00000143373"	"ZNF687"	"D3DV17; hsa:57592; Q68DQ8; Q8N1G0; Q9H937; Q9P2A7"	""	""	"0"	"0"	"130.9"	"25.0"	"199.9"	"161.2"	"107.1"	"127.4"	"310.2"	"277.2"	"407.1"	"770.9"	"1469.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q68E01"	"Integrator complex subunit 3 OS=Homo sapiens OX=9606 GN=INTS3 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"1043"	"118.0"	"5.80"	""	"6.96"	""	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf10189"	"65123"	"ENSG00000143624; ENSG00000262826"	"INTS3"	"A8K1W0; B4DQC8; B4E3U9; D3DV57; hsa:65123; Q4G0E5; Q5VUQ5; Q5VUQ6; Q5VUR0; Q5VUR1; Q68DJ1; Q68E01; Q69YR5; Q6AI57; Q6DKG7; Q6MZQ4; Q6MZZ9; Q8NC46; Q8TB23; Q9H6S9"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"19.3"	"12.9"	"87.0"	"28.8"	"33.5"	"33.6"	"29.3"	"31.5"	"32.7"	"50.3"	"76.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SB3"	"Neurabin-2 OS=Homo sapiens OX=9606 GN=PPP1R9B PE=1 SV=3"	"0.000"	""	"5"	"3"	"4"	"2"	"817"	"89.3"	"4.97"	"505.19"	"6.96"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00595, Pf17817"	"84687"	"ENSG00000108819"	"PPP1R9B"	"D3DTX6; hsa:84687; Q8TCR9; Q96SB3"	""	""	"0"	"0"	"52.5"	"48.2"	"62.8"	"72.8"	"48.9"	"58.7"	"92.5"	"95.8"	"115.2"	"268.0"	"379.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5L4"	"Mitochondrial import inner membrane translocase subunit Tim13 OS=Homo sapiens OX=9606 GN=TIMM13 PE=1 SV=1"	"0.000"	""	"12"	"1"	"4"	"1"	"95"	"10.5"	"8.18"	"642.52"	"6.95"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02953"	"26517"	"ENSG00000099800"	"TIMM13"	"hsa:26517; P62206; Q9UHL8; Q9WTL1; Q9Y5L4"	""	"Mitochondrial protein import"	"1"	"0"	"41.5"	"31.4"	"54.8"	"63.9"	"44.9"	"37.5"	"66.3"	"87.0"	"105.6"	"307.2"	"481.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13155"	"Aminoacyl tRNA synthase complex-interacting multifunctional protein 2 OS=Homo sapiens OX=9606 GN=AIMP2 PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"320"	"35.3"	"8.22"	"391.11"	"6.95"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14497, Pf16780, Pf18569"	"7965"	"ENSG00000106305"	"AIMP2"	"F8W950; hsa:7965; Q13155; Q75MR1; Q96CZ5; Q9P1L2"	"Osteoclast signaling; Transcriptional activation by NRF2 in response to phytochemicals; NRF2-ARE regulation"	"Cytosolic tRNA aminoacylation; Selenoamino acid metabolism"	"5"	"0"	"23.5"	"20.6"	"35.5"	"59.1"	"32.0"	"26.2"	"66.4"	"68.3"	"127.2"	"524.0"	"706.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96F86"	"Enhancer of mRNA-decapping protein 3 OS=Homo sapiens OX=9606 GN=EDC3 PE=1 SV=1"	"0.000"	""	"7"	"3"	"4"	"3"	"508"	"56.0"	"7.11"	"841.59"	"6.94"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03853, Pf09532, Pf12701, Pf16598"	"80153"	"ENSG00000179151"	"EDC3"	"B3KPH0; D3DW61; hsa:80153; Q96F86; Q9H797"	""	"mRNA decay by 5' to 3' exoribonuclease"	"1"	"0"	"171.3"	"169.4"	"199.3"	"206.1"	"169.0"	"152.6"	"305.9"	"322.5"	"445.7"	"1032.8"	"1410.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GM8"	"Target of EGR1 protein 1 OS=Homo sapiens OX=9606 GN=TOE1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"510"	"56.5"	"7.18"	"401.64"	"6.94"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00642, Pf04857"	"114034"	"ENSG00000132773"	"TOE1"	"B4DEM6; hsa:114034; Q6IA35; Q8IWN5; Q96GM8; Q9H846"	""	""	"0"	"0"	"41.7"	"43.1"	"59.5"	"74.1"	"42.2"	"43.8"	"91.3"	"103.6"	"191.9"	"527.5"	"618.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61599"	"N-alpha-acetyltransferase 20 OS=Homo sapiens OX=9606 GN=NAA20 PE=1 SV=1"	"0.000"	""	"15"	"2"	"4"	"2"	"178"	"20.4"	"5.03"	"706.36"	"6.93"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"51126"	"ENSG00000173418"	"NAA20"	"A6NHA3; B2R4G4; hsa:51126; P61599; Q5TFT7; Q9D7H8; Q9H0Y4; Q9NQH6; Q9Y6D2"	"Metapathway biotransformation Phase I and II"	""	"1"	"0"	"38.4"	"42.1"	"64.9"	"61.0"	"59.8"	"50.1"	"116.2"	"126.6"	"211.7"	"515.4"	"675.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49643"	"DNA primase large subunit OS=Homo sapiens OX=9606 GN=PRIM2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"509"	"58.8"	"7.91"	"681.18"	"6.93"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf04104"	"5558"	"ENSG00000146143"	"PRIM2"	"hsa:5558; P49643; Q53FJ8; Q6P1Q7; Q8WVL2; Q9H413"	"Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"Defective pyroptosis; Polymerase switching on the C-strand of the telomere; Polymerase switching; Activation of the pre-replicative complex; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Telomere C-strand synthesis initiation; DNA replication initiation; Removal of the Flap Intermediate"	"12"	"0"	"57.1"	"49.8"	"61.0"	"81.3"	"58.8"	"52.4"	"109.6"	"116.0"	"167.2"	"517.4"	"653.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVZ3"	"Adaptin ear-binding coat-associated protein 2 OS=Homo sapiens OX=9606 GN=NECAP2 PE=1 SV=1"	"0.000"	""	"12"	"3"	"5"	"2"	"263"	"28.3"	"8.38"	"1005.33"	"6.93"	"3"	"2"	"transport"	"plasma membrane;other membranes"	""	"Pf07933"	"55707"	"ENSG00000157191"	"NECAP2"	"B4DY19; E9PGQ8; hsa:55707; Q5VSU4; Q5VSU5; Q9H7L1; Q9H8L1; Q9NVZ3"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"1"	"140.4"	"129.6"	"160.9"	"203.1"	"172.8"	"310.4"	"1279.4"	"1391.9"	"1330.7"	"998.2"	"1012.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86TJ2"	"Transcriptional adapter 2-beta OS=Homo sapiens OX=9606 GN=TADA2B PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"420"	"48.4"	"7.83"	"844.95"	"6.92"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00249"	"93624"	"ENSG00000173011"	"TADA2B"	"A0AUJ8; A4QMR7; B3KSN0; B3KU86; hsa:93624; Q6MZG9; Q86TJ2"	""	"HATs acetylate histones; Ub-specific processing proteases"	"2"	"0"	"28.0"	"41.7"	"29.6"	"40.6"	"35.1"	"28.8"	"74.3"	"82.2"	"111.9"	"218.9"	"206.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99996"	"A-kinase anchor protein 9 OS=Homo sapiens OX=9606 GN=AKAP9 PE=1 SV=4"	"0.000"	""	"1"	"4"	"6"	"3"	"3907"	"452.7"	"4.98"	"1352.78"	"6.92"	"4"	"2"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf10495"	"10142"	"ENSG00000127914"	"AKAP9"	"A4D1F0; A4D1F2; A4D1F4; hsa:10142; O14869; O43355; O94895; Q75N20; Q99996; Q9UQH3; Q9UQQ4; Q9Y6B8; Q9Y6Y2"	"G protein signaling pathways; NO/cGMP/PKG mediated neuroprotection"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Signaling by BRAF and RAF1 fusions; Phase 3 - rapid repolarisation; Phase 2 - plateau phase"	"12"	"0"	"65.8"	"58.7"	"79.0"	"90.6"	"75.0"	"79.6"	"108.6"	"115.5"	"169.8"	"357.5"	"516.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULH0"	"Kinase D-interacting substrate of 220 kDa OS=Homo sapiens OX=9606 GN=KIDINS220 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"1771"	"196.4"	"6.62"	"420.40"	"6.91"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf07693, Pf12796"	"57498"	"ENSG00000134313"	"KIDINS220"	"A1L4N4; hsa:57498; Q4VC08; Q6MZU2; Q9H889; Q9H9E4; Q9NT37; Q9UF42; Q9ULH0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Neural crest cell migration in cancer"	"RND2 GTPase cycle; RND1 GTPase cycle; ARMS-mediated activation"	"5"	"0"	"15.8"	"8.8"	"16.7"	"20.8"	"13.2"	"16.3"	"34.0"	"43.5"	"74.1"	"172.2"	"251.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5K6"	"CD2-associated protein OS=Homo sapiens OX=9606 GN=CD2AP PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"639"	"71.4"	"6.40"	"606.83"	"6.90"	"2"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00018, Pf14604"	"23607"	"ENSG00000198087"	"CD2AP"	"A6NL34; hsa:23607; Q5VYA3; Q9UG97; Q9Y5K6"	"Primary focal segmental glomerulosclerosis (FSGS); Nephrotic syndrome; Genes controlling nephrogenesis; GDNF signaling"	"Nephrin family interactions"	"5"	"0"	"51.1"	"41.9"	"47.7"	"63.9"	"47.0"	"41.0"	"92.5"	"92.8"	"172.2"	"459.8"	"635.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96Q05"	"Trafficking protein particle complex subunit 9 OS=Homo sapiens OX=9606 GN=TRAPPC9 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1148"	"128.4"	"6.62"	"747.75"	"6.90"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf08626"	"83696"	"ENSG00000167632"	"TRAPPC9"	"hsa:83696; Q4VTT3; Q658K7; Q6P149; Q6ZQT3; Q7L5C4; Q86Y21; Q96Q05; Q96SL2; Q9BQA2"	""	"COPII-mediated vesicle transport; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"4.9"	"0.0"	"6.9"	"7.2"	"9.2"	"9.6"	"14.2"	"17.9"	"13.4"	"23.1"	"24.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60678"	"Protein arginine N-methyltransferase 3 OS=Homo sapiens OX=9606 GN=PRMT3 PE=1 SV=4"	"0.000"	""	"5"	"2"	"4"	"2"	"531"	"59.9"	"5.35"	"668.64"	"6.90"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;other molecular function"	"Pf06325"	"10196"	"ENSG00000185238"	"PRMT3"	"A0A0A0MSN7; B4DUC7; hsa:10196; O60678"	"Nitric oxide metabolism in cystic fibrosis"	"RMTs methylate histone arginines; Protein methylation"	"3"	"0"	"59.3"	"55.0"	"86.6"	"92.5"	"57.9"	"59.7"	"105.0"	"113.5"	"130.5"	"345.7"	"518.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60488"	"Long-chain-fatty-acid--CoA ligase 4 OS=Homo sapiens OX=9606 GN=ACSL4 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"1"	"711"	"79.1"	"8.38"	"571.91"	"6.90"	"2"	"2"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00501"	"2182"	"ENSG00000068366"	"ACSL4"	"D3DUY2; hsa:2182; O60488; O60848; O60849; Q5JWV8"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Ferroptosis; Thermogenesis; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-3 / omega-6 fatty acid synthesis; Omega-9 fatty acid synthesis; Fatty acid transporters; Mitochondrial fatty acid oxidation disorders"	"Synthesis of very long-chain fatty acyl-CoAs; Intracellular metabolism of fatty acids regulates insulin secretion"	"13"	"0"	"85.6"	"121.4"	"67.5"	"85.6"	"74.0"	"81.9"	"118.2"	"152.0"	"177.6"	"380.3"	"424.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3SY69"	"Mitochondrial 10-formyltetrahydrofolate dehydrogenase OS=Homo sapiens OX=9606 GN=ALDH1L2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"923"	"101.7"	"6.52"	"268.03"	"6.89"	"1"	"2"	"other metabolic processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf00171, Pf00550, Pf00551, Pf02911"	"160428"	"ENSG00000136010"	"ALDH1L2"	"hsa:160428; Q3SY68; Q3SY69; Q68D62; Q6AI55; Q8N922"	""	"Metabolism of folate and pterines"	"1"	"0"	"10.8"	"3.5"	"9.2"	"8.9"	"11.4"	"8.7"	"16.1"	"20.3"	"26.5"	"53.4"	"90.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60825"	"6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 OS=Homo sapiens OX=9606 GN=PFKFB2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"505"	"58.4"	"8.38"	"718.19"	"6.89"	"2"	"2"	"other metabolic processes;other biological processes"	"cytosol;nucleus"	"kinase activity;other molecular function"	"Pf00300, Pf01591"	"5208"	"ENSG00000123836"	"PFKFB2"	"hsa:5208; O60824; O60825; Q5VVQ3; Q5VVQ4; Q9H3P1"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism"	"3"	"0"	"28.8"	"31.0"	"35.0"	"43.5"	"27.4"	"32.3"	"49.7"	"51.6"	"71.7"	"191.8"	"280.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWU0"	"Kanadaptin OS=Homo sapiens OX=9606 GN=SLC4A1AP PE=1 SV=1"	"0.000"	""	"4"	"3"	"5"	"3"	"796"	"88.8"	"5.19"	"1161.54"	"6.88"	"3"	"2"	""	"plasma membrane;other membranes;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00498"	"22950"	"ENSG00000163798"	"SLC4A1AP"	"A6NJ39; hsa:22950; Q4KMT1; Q4KMX0; Q7Z5Q9; Q9BWU0; Q9NVN2"	""	""	"0"	"0"	"166.1"	"160.2"	"189.4"	"231.0"	"167.7"	"166.5"	"213.7"	"258.2"	"289.3"	"762.6"	"1449.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAD8"	"Smad nuclear-interacting protein 1 OS=Homo sapiens OX=9606 GN=SNIP1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"396"	"45.8"	"9.99"	"779.99"	"6.88"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf00498"	"79753"	"ENSG00000163877"	"SNIP1"	"hsa:79753; Q8TAD8; Q96SP9; Q9H9T7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"34.3"	"27.2"	"32.9"	"37.8"	"27.4"	"37.1"	"54.7"	"51.1"	"77.5"	"383.0"	"569.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55145"	"Mesencephalic astrocyte-derived neurotrophic factor OS=Homo sapiens OX=9606 GN=MANF PE=1 SV=3"	"0.000"	""	"10"	"3"	"5"	"3"	"182"	"20.7"	"8.69"	"1156.71"	"6.88"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf10208, Pf20145"	"7873"	"ENSG00000145050"	"MANF"	"hsa:7873; P55145; Q14CX4; Q86U67; Q96IS4"	"Orexin receptor pathway"	"Platelet degranulation"	"2"	"0"	"306.5"	"252.6"	"334.8"	"425.0"	"287.7"	"277.0"	"853.9"	"978.0"	"1506.4"	"2221.9"	"2151.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15651"	"High mobility group nucleosome-binding domain-containing protein 3 OS=Homo sapiens OX=9606 GN=HMGN3 PE=1 SV=2"	"0.000"	""	"30"	"2"	"3"	"2"	"99"	"10.7"	"9.66"	"276.94"	"6.88"	"1"	"2"	"cell organization and biogenesis"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01101"	"9324"	"ENSG00000118418"	"HMGN3"	"B2RD37; hsa:9324; Q15651; Q5HYD3; Q7RTT0; Q969M5; Q9BZT7"	""	""	"0"	"0"	"163.6"	"137.3"	"146.3"	"148.0"	"136.4"	"142.1"	"186.7"	"195.3"	"238.0"	"263.4"	"233.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD3"	"39S ribosomal protein L4, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL4 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"311"	"34.9"	"9.72"	"790.86"	"6.84"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00573"	"51073"	"ENSG00000105364"	"MRPL4"	"A6NNV7; hsa:51073; Q9BW07; Q9BYD3; Q9H4N2; Q9Y317"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"24.6"	"24.1"	"32.2"	"38.8"	"24.4"	"19.2"	"45.6"	"53.3"	"63.9"	"152.1"	"247.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW13"	"RNA-binding protein 28 OS=Homo sapiens OX=9606 GN=RBM28 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"759"	"85.7"	"9.22"	"787.11"	"6.83"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf00076"	"55131"	"ENSG00000106344"	"RBM28"	"A4D100; B4DU52; E9PDD9; hsa:55131; Q53H65; Q96CV3; Q9NW13"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"116.1"	"94.5"	"171.8"	"146.7"	"109.8"	"95.8"	"198.3"	"229.3"	"349.3"	"517.3"	"727.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15050"	"Ribosome biogenesis regulatory protein homolog OS=Homo sapiens OX=9606 GN=RRS1 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"365"	"41.2"	"10.70"	""	"6.83"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04939"	"23212"	"ENSG00000179041"	"RRS1"	"hsa:23212; Q15050; Q9BUX8"	""	""	"0"	"0"	"21.1"	"25.9"	"31.2"	"43.3"	"32.0"	"27.5"	"37.8"	"48.3"	"55.7"	"113.7"	"180.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62917"	"60S ribosomal protein L8 OS=Homo sapiens OX=9606 GN=RPL8 PE=1 SV=2"	"0.000"	""	"7"	"3"	"5"	"3"	"257"	"28.0"	"11.03"	"1035.87"	"6.83"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00181, Pf03947"	"6132"	"ENSG00000161016"	"RPL8"	"A8K094; D3DWN2; hsa:6132; P25120; P62917; Q567Q7; Q969V7; Q9BWQ9"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"349.2"	"424.1"	"468.6"	"573.2"	"412.2"	"411.0"	"667.3"	"672.2"	"837.1"	"1941.5"	"2869.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PJT7"	"Zinc finger CCCH domain-containing protein 14 OS=Homo sapiens OX=9606 GN=ZC3H14 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"736"	"82.8"	"7.31"	"989.22"	"6.82"	"2"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf14608"	"79882"	"ENSG00000100722"	"ZC3H14"	"A8MY46; B4DXU8; B4DZW7; B4E2H4; G3V5R4; hsa:79882; Q6MZU4; Q6PJ32; Q6PJT7; Q6PUI6; Q6PUI8; Q86TQ5; Q86TW0; Q86TW1; Q8NCT6; Q8NCZ3; Q8TDE2; Q9HAC9; Q9Y5A0"	""	""	"0"	"0"	"36.8"	"46.6"	"42.9"	"43.5"	"38.3"	"35.0"	"53.8"	"54.1"	"56.4"	"90.1"	"124.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6WKZ4"	"Rab11 family-interacting protein 1 OS=Homo sapiens OX=9606 GN=RAB11FIP1 PE=1 SV=3"	"0.000"	""	"2"	"3"	"5"	"3"	"1283"	"137.1"	"5.43"	"1026.07"	"6.81"	"3"	"2"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00168, Pf09457"	"80223"	"ENSG00000156675"	"RAB11FIP1"	"hsa:80223; J3KNP0; Q307T1; Q6AZK4; Q6WKZ2; Q6WKZ4; Q6WKZ6; Q86YV4; Q8TDL1; Q9H642"	""	""	"0"	"0"	"121.0"	"102.8"	"153.0"	"171.6"	"160.6"	"294.5"	"611.6"	"666.4"	"644.5"	"723.6"	"790.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00492"	"Hypoxanthine-guanine phosphoribosyltransferase OS=Homo sapiens OX=9606 GN=HPRT1 PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"2"	"218"	"24.6"	"6.68"	"910.56"	"6.81"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00156"	"3251"	"ENSG00000165704"	"HPRT1"	"A6NHF0; B2R8M9; hsa:3251; P00492"	"Mesodermal commitment pathway"	"Azathioprine ADME; Purine salvage; Defective HPRT1 disrupts guanine and hypoxanthine salvage"	"4"	"0"	"49.1"	"51.5"	"70.6"	"134.0"	"42.5"	"23.4"	"85.8"	"87.0"	"105.1"	"215.7"	"262.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L93"	"Kinesin-like protein KIF16B OS=Homo sapiens OX=9606 GN=KIF16B PE=1 SV=2"	"0.000"	""	"1"	"1"	"4"	"1"	"1317"	"151.9"	"6.16"	"813.00"	"6.80"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf00787"	"55614"	"ENSG00000089177"	"KIF16B"	"A6NKJ9; A7E2A8; B1AKG3; B1AKT7; C9JDN5; C9JI52; C9JSM8; C9JWJ7; hsa:55614; Q2TBF5; Q5HYC0; Q5HYK1; Q5JWW3; Q5TFK5; Q86VL9; Q86YS5; Q8IYU0; Q96L93; Q9BQJ8; Q9BQM0; Q9BQM1; Q9BQM5; Q9H5U0; Q9HCI2; Q9NXN9"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	"58.7"	"55.3"	"68.7"	"87.3"	"59.9"	"61.5"	"118.1"	"117.8"	"177.6"	"252.4"	"307.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YQ0"	"Cytospin-A OS=Homo sapiens OX=9606 GN=SPECC1L PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1117"	"124.5"	"5.72"	"1178.08"	"6.79"	"3"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"187.4"	"155.1"	"220.8"	"205.7"	"185.6"	"179.3"	"244.9"	"245.0"	"297.4"	"576.2"	"757.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1K2"	"Polyamine-modulated factor 1 OS=Homo sapiens OX=9606 GN=PMF1 PE=1 SV=2"	"0.000"	""	"11"	"2"	"4"	"2"	"205"	"23.3"	"5.49"	"632.42"	"6.79"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf03980"	"100527963; 11243"	"ENSG00000160783"	"PMF1"	"A8K0C5; hsa:100527963; hsa:11243; Q5TCJ8; Q5TCJ9; Q5TCK0; Q5TCK1; Q5TCK3; Q69YZ9; Q6P1K2; Q6PHR4; Q6ZVE6; Q86VJ6; Q8N4T6; Q9UBQ3"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"70.5"	"67.7"	"83.1"	"98.1"	"60.3"	"64.0"	"192.9"	"201.9"	"399.5"	"1484.1"	"2137.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBC3"	"DNA (cytosine-5)-methyltransferase 3B OS=Homo sapiens OX=9606 GN=DNMT3B PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"853"	"95.7"	"8.43"	"598.47"	"6.78"	"2"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00145, Pf00855, Pf17980"	"1789"	"ENSG00000088305"	"DNMT3B"	"A2A2E2; B4DSM8; B4DSU1; E1P5M6; E1P5M7; E7EN63; E9PBF2; hsa:1789; Q9UBC3; Q9UBD4; Q9UJQ5; Q9UKA6; Q9UNE5; Q9Y5R9; Q9Y5S0"	"One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Mesodermal commitment pathway; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; MTHFR deficiency"	"NoRC negatively regulates rRNA expression; PRC2 methylates histones and DNA; Defective pyroptosis; DNA methylation; SUMOylation of DNA methylation proteins"	"10"	"0"	"8.0"	"7.4"	"7.4"	"7.2"	"7.1"	"5.2"	"9.6"	"13.3"	"17.1"	"24.0"	"28.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14156"	"Protein EFR3 homolog A OS=Homo sapiens OX=9606 GN=EFR3A PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"821"	"92.9"	"6.70"	"303.98"	"6.77"	"1"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	""	""	"23167"	"ENSG00000132294"	"EFR3A"	"A7MD19; hsa:23167; Q14156; Q2VPK2; Q63HL7; Q68DX1; Q6IQ18"	""	""	"0"	"0"	"13.1"	"8.2"	"12.3"	"9.6"	"4.3"	"10.6"	"20.1"	"18.1"	"38.6"	"76.2"	"98.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43813"	"Glutathione S-transferase LANCL1 OS=Homo sapiens OX=9606 GN=LANCL1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"399"	"45.3"	"7.75"	"735.48"	"6.77"	"2"	"2"	"other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf05147"	"10314"	"ENSG00000115365"	"LANCL1"	"hsa:10314; O43813"	""	""	"0"	"0"	"33.9"	"36.7"	"49.1"	"64.8"	"38.6"	"36.3"	"73.2"	"76.6"	"128.6"	"286.0"	"488.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ69"	"ADP-ribose glycohydrolase MACROD1 OS=Homo sapiens OX=9606 GN=MACROD1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"325"	"35.5"	"9.51"	"696.60"	"6.76"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"nucleus"	"other molecular function"	"Pf01661"	"28992"	"ENSG00000133315"	"MACROD1"	"hsa:28992; Q9BQ69; Q9UH96"	""	""	"0"	"0"	"46.2"	"42.2"	"61.8"	"64.1"	"47.5"	"44.4"	"133.9"	"150.3"	"231.3"	"564.6"	"596.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43034"	"Platelet-activating factor acetylhydrolase IB subunit alpha OS=Homo sapiens OX=9606 GN=PAFAH1B1 PE=1 SV=2"	"0.000"	""	"8"	"3"	"4"	"3"	"410"	"46.6"	"7.37"	"1309.30"	"6.76"	"3"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08513"	"5048"	"ENSG00000007168"	"PAFAH1B1"	"B2R7Q7; hsa:5048; P43034; Q8WZ88; Q8WZ89"	"Wnt signaling pathway and pluripotency; Ciliary landscape; Neurogenesis regulation in the olfactory epithelium; PAFAH1B1 copy number variation"	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; Recruitment of NuMA to mitotic centrosomes; COPI-independent Golgi-to-ER retrograde traffic; EML4 and NUDC in mitotic spindle formation; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"18"	"0"	"205.4"	"185.4"	"192.1"	"253.6"	"166.6"	"165.6"	"352.5"	"381.3"	"588.0"	"1960.5"	"3003.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13526"	"Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 OS=Homo sapiens OX=9606 GN=PIN1 PE=1 SV=1"	"0.000"	""	"14"	"2"	"4"	"2"	"163"	"18.2"	"8.82"	"793.17"	"6.75"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00639"	"5300"	"ENSG00000127445"	"PIN1"	"A8K4V9; hsa:5300; Q13526; Q53X75"	"Novel intracellular components of RIG-I-like receptor pathway"	"Regulation of TP53 Activity through Phosphorylation; ISG15 antiviral mechanism; Negative regulators of DDX58/IFIH1 signaling; PI5P Regulates TP53 Acetylation; RHO GTPases Activate NADPH Oxidases"	"6"	"0"	"111.2"	"83.0"	"112.7"	"138.0"	"91.8"	"88.6"	"148.5"	"159.1"	"193.7"	"385.3"	"673.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q06265"	"Exosome complex component RRP45 OS=Homo sapiens OX=9606 GN=EXOSC9 PE=1 SV=3"	""	""	"2"	"1"	"2"	"1"	"439"	"48.9"	"5.29"	""	"6.74"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"5393"	"ENSG00000123737"	"EXOSC9"	"hsa:5393; Q06265; Q12883; Q4W5P5; Q86Y41; Q86Y48"	"Ciliary landscape"	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"49.1"	"42.8"	"55.7"	"72.0"	"49.3"	"44.2"	"99.9"	"102.7"	"166.4"	"539.7"	"893.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5QJE6"	"Deoxynucleotidyltransferase terminal-interacting protein 2 OS=Homo sapiens OX=9606 GN=DNTTIP2 PE=1 SV=2"	"0.000"	""	"4"	"3"	"5"	"3"	"756"	"84.4"	"6.16"	"816.59"	"6.73"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf08698"	"30836"	"ENSG00000067334"	"DNTTIP2"	"hsa:30836; Q12987; Q53H59; Q5QJE6; Q5TFJ4; Q6TLI0; Q76MJ8; Q86WX9"	""	""	"0"	"0"	"203.1"	"184.8"	"198.7"	"251.5"	"194.3"	"189.1"	"299.7"	"319.9"	"406.7"	"949.1"	"1206.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCS7"	"Pre-mRNA-splicing factor SYF1 OS=Homo sapiens OX=9606 GN=XAB2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"855"	"99.9"	"6.23"	"786.70"	"6.72"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes"	"nucleus;other cell component"	""	"Pf13181"	"56949"	"ENSG00000076924"	"XAB2"	"hsa:56949; Q8TET6; Q96HB0; Q96IW0; Q9HCS7; Q9NRG6; Q9ULP3"	"Rett syndrome causing genes; Nucleotide excision repair in xeroderma pigmentosum"	"mRNA Splicing - Major Pathway; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER"	"7"	"0"	"190.8"	"150.5"	"212.5"	"235.6"	"160.9"	"185.8"	"251.0"	"265.5"	"291.1"	"832.4"	"1340.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z392"	"Trafficking protein particle complex subunit 11 OS=Homo sapiens OX=9606 GN=TRAPPC11 PE=1 SV=2"	"0.000"	""	"4"	"3"	"4"	"3"	"1133"	"128.8"	"7.14"	"931.36"	"6.71"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;other cell component"	""	"Pf11817, Pf12742"	"60684"	"ENSG00000168538"	"TRAPPC11"	"A4QPB8; B2RCD6; hsa:60684; Q5U5I7; Q6FI73; Q7Z392; Q86T25; Q9H0L1; Q9H5K9; Q9H8Q1; Q9H9I7"	"Genes related to primary cilium development (based on CRISPR)"	"RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"11.0"	"18.3"	"8.2"	"29.8"	"16.6"	"14.9"	"53.0"	"58.0"	"97.4"	"254.7"	"402.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6H7"	"ADP-ribosylation factor GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=ARFGAP2 PE=1 SV=1"	"0.000"	""	"7"	"4"	"6"	"4"	"521"	"56.7"	"7.99"	"1336.42"	"6.70"	"4"	"2"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"84364"	"ENSG00000149182"	"ARFGAP2"	"B4DX29; B7Z9M7; D3DQQ9; hsa:84364; Q3LIF2; Q8N3I1; Q8N6H7; Q96SX7"	"IL-18 signaling pathway; 5q35 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; CDC42 GTPase cycle"	"5"	"0"	"337.1"	"299.7"	"355.6"	"399.8"	"299.6"	"332.7"	"490.5"	"503.7"	"687.9"	"1169.2"	"1263.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48059"	"LIM and senescent cell antigen-like-containing domain protein 1 OS=Homo sapiens OX=9606 GN=LIMS1 PE=1 SV=4"	"0.000"	""	"7"	"2"	"4"	"2"	"325"	"37.2"	"8.05"	"777.27"	"6.69"	"2"	"2"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00412"	"3987"	"ENSG00000169756"	"LIMS1"	"B2RAJ4; B7Z483; B7Z7R3; B7Z907; hsa:3987; P48059; Q53TE0; Q9BS44"	"Primary focal segmental glomerulosclerosis (FSGS)"	"Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"3"	"0"	"87.5"	"76.7"	"101.4"	"120.6"	"87.8"	"62.7"	"277.8"	"298.6"	"573.6"	"1065.3"	"1049.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13206"	"Probable ATP-dependent RNA helicase DDX10 OS=Homo sapiens OX=9606 GN=DDX10 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"875"	"100.8"	"8.63"	"887.13"	"6.69"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"1662"	"ENSG00000178105"	"DDX10"	"B2RCQ3; hsa:1662; Q13206; Q5BJD8"	""	""	"0"	"0"	"19.7"	"15.8"	"24.4"	"34.2"	"21.6"	"24.2"	"38.5"	"37.1"	"53.2"	"147.4"	"235.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94887"	"FERM, ARHGEF and pleckstrin domain-containing protein 2 OS=Homo sapiens OX=9606 GN=FARP2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1054"	"119.8"	"8.79"	"569.40"	"6.67"	"2"	"2"	"cell adhesion;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"9855"	"ENSG00000006607"	"FARP2"	"B7Z6J8; F5GZ84; hsa:9855; O94887; Q53QM5; Q8WU27; Q9UFE7"	"2q37 copy number variation syndrome; TAR syndrome"	"RAC1 GTPase cycle; SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion"	"4"	"0"	"211.1"	"233.5"	"228.6"	"243.7"	"212.8"	"237.5"	"323.0"	"338.2"	"380.6"	"734.0"	"948.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75348"	"V-type proton ATPase subunit G 1 OS=Homo sapiens OX=9606 GN=ATP6V1G1 PE=1 SV=3"	"0.000"	""	"17"	"2"	"4"	"2"	"118"	"13.7"	"8.79"	"713.14"	"6.67"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf03179"	"9550"	"ENSG00000136888"	"ATP6V1G1"	"hsa:9550; O75348; Q6IB33"	"Osteoclast signaling; Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"7"	"0"	"243.4"	"251.5"	"202.9"	"262.9"	"202.4"	"212.6"	"295.3"	"321.7"	"357.3"	"691.4"	"860.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02218"	"2-oxoglutarate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=OGDH PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"1023"	"115.9"	"6.86"	"701.21"	"6.66"	"2"	"2"	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00676, Pf02779, Pf16078, Pf16870"	"4967"	"ENSG00000105953"	"OGDH"	"B4E2U9; D3DVL0; E9PBM1; hsa:4967; Q02218; Q96DD3; Q9UDX0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Thiamine metabolic pathways; 7q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Lysine catabolism; Glyoxylate metabolism and glycine degradation; Citric acid cycle (TCA cycle)"	"8"	"0"	"198.4"	"167.2"	"196.0"	"246.1"	"170.8"	"182.2"	"239.4"	"224.1"	"246.3"	"392.1"	"580.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB78"	"Lysine-specific histone demethylase 1B OS=Homo sapiens OX=9606 GN=KDM1B PE=1 SV=3"	"0.000"	""	"4"	"3"	"5"	"3"	"822"	"92.0"	"7.87"	"1376.58"	"6.66"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01593, Pf04433, Pf07496"	"221656"	"ENSG00000165097"	"KDM1B"	"A2A2C5; A2A2C6; hsa:221656; Q5TGV3; Q6AI15; Q6ZUU4; Q8N258; Q8NB78; Q96EL7"	"Vitamin D-sensitive calcium signaling in depression"	"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; UCH proteinases; HDMs demethylate histones"	"4"	"0"	"64.4"	"51.4"	"65.2"	"76.1"	"55.1"	"58.0"	"147.8"	"147.5"	"269.9"	"725.9"	"824.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27797"	"Calreticulin OS=Homo sapiens OX=9606 GN=CALR PE=1 SV=1"	"0.000"	""	"10"	"4"	"6"	"4"	"417"	"48.1"	"4.44"	"1229.59"	"6.65"	"4"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf00262"	"811"	"ENSG00000179218"	"CALR"	"hsa:811; P27797; Q6IAT4; Q9UDG2"	"Androgen receptor signaling pathway; Complement system; Photodynamic therapy-induced unfolded protein response; VEGFA-VEGFR2 signaling; GDNF signaling; Calcium regulation in cardiac cells"	"ER-Phagosome pathway; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Scavenging by Class A Receptors; Assembly of Viral Components at the Budding Site; Scavenging by Class F Receptors; ATF6 (ATF6-alpha) activates chaperone genes; Calnexin/calreticulin cycle"	"13"	"0"	"407.1"	"354.9"	"391.7"	"555.2"	"356.7"	"326.0"	"538.8"	"531.0"	"625.1"	"1022.5"	"1170.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08AD1"	"Calmodulin-regulated spectrin-associated protein 2 OS=Homo sapiens OX=9606 GN=CAMSAP2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1489"	"168.0"	"6.80"	"614.76"	"6.65"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;ER/Golgi"	"cytoskeletal activity;other molecular function"	"Pf08683, Pf11971, Pf17095"	"23271"	"ENSG00000118200"	"CAMSAP2"	"B1APG6; hsa:23271; Q08AD1; Q08AD2; Q6PGN8; Q96FB3; Q9UG20; Q9UPS4"	""	""	"0"	"0"	"16.9"	"9.9"	"12.2"	"15.0"	"10.5"	"13.4"	"11.9"	"14.3"	"20.4"	"30.5"	"31.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07947"	"Tyrosine-protein kinase Yes OS=Homo sapiens OX=9606 GN=YES1 PE=1 SV=3"	"0.000"	""	"7"	"3"	"5"	"3"	"543"	"60.8"	"6.74"	"1047.85"	"6.65"	"3"	"2"	"protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"7525"	"ENSG00000176105"	"YES1"	"A6NLB3; D3DUH1; hsa:7525; P07947"	"Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; NRF2-ARE regulation; Gastrin signaling pathway; GDNF signaling"	"FCGR activation; FCGR3A-mediated IL10 synthesis; FCGR3A-mediated phagocytosis; Regulation of signaling by CBL; EPHB-mediated forward signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Regulation of KIT signaling; Signaling by ERBB2; EPH-ephrin mediated repulsion of cells; EPHA-mediated growth cone collapse; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; CD28 co-stimulation; PECAM1 interactions; CTLA4 inhibitory signaling"	"22"	"0"	"158.3"	"150.0"	"161.3"	"214.5"	"141.9"	"148.8"	"233.0"	"254.2"	"316.8"	"724.0"	"1077.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51397"	"Death-associated protein 1 OS=Homo sapiens OX=9606 GN=DAP PE=1 SV=3"	""	""	"25"	"1"	"1"	"1"	"102"	"11.2"	"9.32"	""	"6.64"	""	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	""	"other molecular function"	"Pf15228"	"1611"	"ENSG00000112977"	"DAP"	"hsa:1611; P51397; Q6FGC3; Q9BUC9"	""	""	"0"	"0"	"50.0"	"35.4"	"51.3"	"62.9"	"43.9"	"48.8"	"70.0"	"72.1"	"88.2"	"227.8"	"448.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96G46"	"tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like OS=Homo sapiens OX=9606 GN=DUS3L PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"650"	"72.5"	"8.05"	"627.59"	"6.62"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	""	"other molecular function"	"Pf01207, Pf18044"	"56931"	"ENSG00000141994"	"DUS3L"	"hsa:56931; Q96G46; Q96HM5; Q9BSU4; Q9H877; Q9NPR1"	""	""	"0"	"0"	"60.9"	"49.9"	"67.4"	"74.1"	"61.2"	"53.2"	"82.3"	"86.3"	"97.2"	"135.4"	"190.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQH7"	"Xaa-Pro aminopeptidase 3 OS=Homo sapiens OX=9606 GN=XPNPEP3 PE=1 SV=1"	"0.001"	""	"6"	"2"	"3"	"1"	"507"	"57.0"	"6.83"	"234.85"	"6.60"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00557, Pf05195"	"63929"	"ENSG00000196236"	"XPNPEP3"	"B2R9G1; B7Z790; B7Z7B2; hsa:63929; Q6I9V9; Q8NDA6; Q9BV27; Q9BVH0; Q9NQH7"	"Ciliary landscape; Ciliopathies"	""	"2"	"0"	"19.5"	"16.3"	"21.6"	"22.1"	"16.7"	"13.8"	"27.4"	"31.8"	"40.8"	"90.8"	"122.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBE0"	"SUMO-activating enzyme subunit 1 OS=Homo sapiens OX=9606 GN=SAE1 PE=1 SV=1"	"0.001"	""	"10"	"2"	"3"	"2"	"346"	"38.4"	"5.30"	"237.30"	"6.59"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00899"	"10055"	"ENSG00000142230"	"SAE1"	"B2RDP5; B3KMQ2; F5GXX7; G3XAK6; hsa:10055; O95717; Q9P020; Q9UBE0"	""	"SUMO is conjugated to E1 (UBA2:SAE1); SUMO is transferred from E1 to E2 (UBE2I, UBC9)"	"2"	"0"	"18.3"	"26.4"	"35.7"	"48.1"	"23.7"	"20.3"	"42.2"	"34.0"	"44.1"	"109.5"	"169.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NYI0"	"PH and SEC7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=PSD3 PE=1 SV=2"	""	""	"3"	"2"	"2"	"2"	"1048"	"116.0"	"5.99"	""	"6.58"	""	"2"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity"	"Pf01369, Pf15410"	"23362"	"ENSG00000156011"	"PSD3"	"A6NFQ4; E9KL50; hsa:23362; Q6B003; Q9NYI0; Q9Y2F1"	""	""	"0"	"0"	"117.3"	"109.2"	"146.8"	"158.8"	"116.0"	"123.7"	"132.1"	"142.5"	"149.8"	"347.3"	"602.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14258"	"E3 ubiquitin/ISG15 ligase TRIM25 OS=Homo sapiens OX=9606 GN=TRIM25 PE=1 SV=2"	"0.000"	""	"6"	"3"	"5"	"3"	"630"	"70.9"	"8.09"	"1118.39"	"6.57"	"3"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00622, Pf13445, Pf13765"	"7706"	"ENSG00000121060"	"TRIM25"	"hsa:7706; Q14258"	"Novel intracellular components of RIG-I-like receptor pathway; Cytosolic DNA-sensing pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; 1p36 copy number variation syndrome"	"SARS-CoV-1 activates/modulates innate immune responses; ISG15 antiviral mechanism; Interferon gamma signaling; SARS-CoV-2 activates/modulates innate and adaptive immune responses; TRAF6 mediated NF-kB activation; NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10; Termination of translesion DNA synthesis; Negative regulators of DDX58/IFIH1 signaling; Ovarian tumor domain proteases; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"16"	"0"	"27.8"	"23.2"	"32.6"	"48.4"	"32.0"	"25.3"	"62.1"	"49.9"	"81.5"	"183.0"	"263.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4G0"	"Band 4.1-like protein 1 OS=Homo sapiens OX=9606 GN=EPB41L1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"881"	"98.4"	"5.62"	"1127.16"	"6.56"	"3"	"2"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf00373, Pf04382, Pf05902, Pf08736, Pf09379, Pf09380"	"2036"	"ENSG00000088367"	"EPB41L1"	"hsa:2036; O15046; Q4VXM6; Q4VXM7; Q4VXM8; Q4VXN4; Q6ZT61; Q8IUU7; Q96CV5; Q96L65; Q9H4G0"	"Splicing factor NOVA regulated synaptic proteins"	"Trafficking of AMPA receptors; Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea; Neurexins and neuroligins"	"5"	"0"	"63.2"	"65.2"	"64.5"	"84.8"	"51.4"	"52.4"	"142.2"	"169.9"	"306.4"	"511.2"	"540.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12797"	"Aspartyl/asparaginyl beta-hydroxylase OS=Homo sapiens OX=9606 GN=ASPH PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"758"	"85.8"	"5.01"	"1315.67"	"6.55"	"3"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf05118, Pf05279, Pf13432"	"444"	"ENSG00000198363"	"ASPH"	"A0A0A0MSK8; A6NDF4; A6NHI2; B4DIC9; B4E2K4; B7ZM95; E5RGP5; F5H667; hsa:444; Q12797; Q6NXR7; Q8TB28; Q9H291; Q9H2C4; Q9NRI0; Q9NRI1; Q9Y4J0"	""	"Stimuli-sensing channels; Ion homeostasis"	"2"	"0"	"65.0"	"70.9"	"92.5"	"120.7"	"58.2"	"77.0"	"225.5"	"232.5"	"607.9"	"1683.7"	"1749.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61313"	"60S ribosomal protein L15 OS=Homo sapiens OX=9606 GN=RPL15 PE=1 SV=2"	"0.000"	""	"9"	"2"	"4"	"2"	"204"	"24.1"	"11.62"	"832.14"	"6.54"	"2"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00827"	"6138"	"ENSG00000174748"	"RPL15"	"hsa:6138; P39030; P41051; P61313; Q5U0C0; Q642I1; Q6IPX6; Q8WYP2; Q96C44; Q9H2E5"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"82.1"	"124.2"	"97.7"	"159.9"	"90.7"	"85.4"	"180.2"	"195.7"	"258.1"	"648.9"	"970.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14795"	"Protein unc-13 homolog B OS=Homo sapiens OX=9606 GN=UNC13B PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"3"	"1591"	"180.6"	"5.99"	"1219.38"	"6.54"	"3"	"2"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00130, Pf00168, Pf06292"	"10497"	"ENSG00000198722"	"UNC13B"	"hsa:10497; O14795; Q2NKJ5; Q5VYM8"	"Synaptic vesicle pathway; 16p11.2 proximal deletion syndrome; Monoamine transport"	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle"	"8"	"0"	"15.1"	"13.1"	"29.3"	"29.2"	"19.2"	"25.4"	"76.4"	"74.9"	"130.0"	"227.0"	"253.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96TA2"	"ATP-dependent zinc metalloprotease YME1L1 OS=Homo sapiens OX=9606 GN=YME1L1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"4"	"1"	"773"	"86.4"	"8.76"	"685.57"	"6.53"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00004, Pf01434, Pf17862"	"10730"	"ENSG00000136758"	"YME1L1"	"B4DNM1; D3DRV8; D3DRV9; hsa:10730; Q5T8D9; Q96TA2; Q9H1Q0; Q9UMR9"	""	"Processing of SMDT1"	"1"	"0"	"5.5"	"3.0"	"5.8"	"8.1"	"5.8"	"5.7"	"11.1"	"6.9"	"8.9"	"24.2"	"38.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ24"	"Zinc finger FYVE domain-containing protein 21 OS=Homo sapiens OX=9606 GN=ZFYVE21 PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"2"	"234"	"26.5"	"8.41"	"409.89"	"6.53"	"1"	"2"	""	"other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf16696"	"79038"	"ENSG00000100711"	"ZFYVE21"	"A8K3A4; hsa:79038; Q86T05; Q96LT1; Q9BQ24"	""	""	"0"	"0"	"53.9"	"58.5"	"55.6"	"56.3"	"54.0"	"50.1"	"94.2"	"99.8"	"124.7"	"202.7"	"181.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDN4"	"CDK5 and ABL1 enzyme substrate 1 OS=Homo sapiens OX=9606 GN=CABLES1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"633"	"67.6"	"9.17"	"953.63"	"6.52"	"2"	"2"	"cell cycle OR cell proliferation;developmental processes;other biological processes"	"cytosol;nucleus"	""	"Pf00134"	"91768"	"ENSG00000134508"	"CABLES1"	"B4DK60; hsa:91768; Q8N3Y8; Q8NA22; Q8TDN4; Q9BTG1"	""	"Factors involved in megakaryocyte development and platelet production; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"3"	"0"	"11.3"	"9.0"	"6.7"	"17.3"	"15.3"	"39.2"	"146.0"	"168.6"	"181.9"	"224.2"	"235.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y530"	"ADP-ribose glycohydrolase OARD1 OS=Homo sapiens OX=9606 GN=OARD1 PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"2"	"152"	"17.0"	"8.31"	"700.19"	"6.51"	"2"	"2"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf01661"	"221443"	"ENSG00000124596"	"OARD1"	"A6NEK4; A8K4H4; hsa:221443; Q96F23; Q9Y530"	""	""	"0"	"0"	"109.9"	"133.0"	"117.7"	"138.7"	"94.4"	"109.4"	"187.5"	"215.6"	"284.0"	"554.3"	"590.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7Z3"	"Nuclear exosome regulator NRDE2 OS=Homo sapiens OX=9606 GN=NRDE2 PE=1 SV=3"	"0.000"	""	"2"	"3"	"5"	"3"	"1164"	"132.6"	"7.68"	"978.99"	"6.50"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08424"	"55051"	"ENSG00000119720"	"NRDE2"	"B4DH71; hsa:55051; Q4G0A7; Q9H7Z3; Q9NWH6"	""	""	"0"	"0"	"76.6"	"66.6"	"103.8"	"118.9"	"77.2"	"89.1"	"181.5"	"193.7"	"377.8"	"488.9"	"390.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HBM6"	"Transcription initiation factor TFIID subunit 9B OS=Homo sapiens OX=9606 GN=TAF9B PE=1 SV=1"	"0.000"	""	"12"	"2"	"4"	"2"	"251"	"27.6"	"9.55"	"806.47"	"6.49"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf02291"	"51616"	"ENSG00000187325"	"TAF9B"	"B2RUZ9; hsa:51616; Q9HBM6; Q9Y2S3"	""	"Ub-specific processing proteases; RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"10"	"0"	"21.4"	"27.4"	"29.7"	"39.8"	"27.5"	"21.4"	"41.2"	"45.4"	"79.3"	"217.0"	"280.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4C8"	"Misshapen-like kinase 1 OS=Homo sapiens OX=9606 GN=MINK1 PE=1 SV=2"	"0.000"	""	"3"	"3"	"5"	"1"	"1332"	"149.7"	"7.85"	"1048.30"	"6.46"	"3"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"50488"	"ENSG00000141503"	"MINK1"	"D3DTK3; D3DTK4; hsa:50488; Q5U8Z0; Q8N4C8; Q9P1X1; Q9P2R8"	"Angiopoietin-like protein 8 regulatory pathway; Hippo-YAP signaling; Insulin signaling; Pleural mesothelioma"	"Oxidative Stress Induced Senescence"	"5"	"0"	"27.9"	"18.5"	"34.5"	"26.2"	"26.4"	"32.7"	"47.9"	"38.9"	"55.1"	"72.3"	"86.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L266"	"Isoaspartyl peptidase/L-asparaginase OS=Homo sapiens OX=9606 GN=ASRGL1 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"308"	"32.0"	"6.24"	"341.99"	"6.45"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01112"	"80150"	"ENSG00000162174"	"ASRGL1"	"B2R7Q0; hsa:80150; Q567Q4; Q6P1P0; Q7L266; Q8NI34; Q9H6F7"	""	"Phenylalanine metabolism"	"1"	"0"	"17.6"	"15.0"	"30.4"	"37.5"	"27.9"	"26.9"	"54.8"	"58.8"	"108.5"	"363.5"	"563.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZI7"	"Regulator of nonsense transcripts 3B OS=Homo sapiens OX=9606 GN=UPF3B PE=1 SV=1"	"0.000"	""	"7"	"3"	"5"	"3"	"483"	"57.7"	"9.48"	"1472.53"	"6.45"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf03467"	"65109"	"ENSG00000125351"	"UPF3B"	"D3DWI3; D3DWI4; hsa:65109; Q0VAK8; Q9BZI7; Q9H1J0"	""	"mRNA Splicing - Major Pathway; Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); RNA Polymerase II Transcription Termination; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing"	"6"	"0"	"506.5"	"440.3"	"527.1"	"589.1"	"491.3"	"502.0"	"578.2"	"622.1"	"649.9"	"939.9"	"1094.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAJ7"	"Histone deacetylase complex subunit SAP30L OS=Homo sapiens OX=9606 GN=SAP30L PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"183"	"20.9"	"9.36"	"449.97"	"6.45"	"1"	"2"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"79685"	"ENSG00000164576"	"SAP30L"	"E9PAU7; E9PAY2; hsa:79685; Q9HAJ7"	""	"Potential therapeutics for SARS; NoRC negatively regulates rRNA expression; HDACs deacetylate histones"	"3"	"0"	"107.7"	"71.9"	"146.3"	"197.9"	"118.6"	"78.5"	"231.9"	"238.9"	"339.0"	"974.8"	"1661.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07992"	"DNA excision repair protein ERCC-1 OS=Homo sapiens OX=9606 GN=ERCC1 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"297"	"32.5"	"6.25"	"662.02"	"6.45"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00633, Pf03834"	"2067"	"ENSG00000012061"	"ERCC1"	"B2RC01; B3KRR0; hsa:2067; P07992; Q7Z7F5; Q96S40"	"Male infertility; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"HDR through Single Strand Annealing (SSA); Fanconi Anemia Pathway; Dual incision in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"9"	"0"	"36.9"	"45.3"	"41.2"	"58.9"	"35.6"	"43.7"	"76.5"	"70.4"	"109.6"	"318.6"	"403.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00151"	"PDZ and LIM domain protein 1 OS=Homo sapiens OX=9606 GN=PDLIM1 PE=1 SV=4"	"0.000"	""	"6"	"2"	"3"	"2"	"329"	"36.0"	"7.02"	"328.24"	"6.45"	"1"	"2"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"9124"	"ENSG00000107438"	"PDLIM1"	"B2RBS6; hsa:9124; O00151; Q5VZH5; Q9BPZ9"	""	""	"0"	"0"	"70.1"	"54.3"	"88.4"	"123.8"	"68.3"	"65.0"	"112.4"	"106.6"	"126.6"	"562.3"	"1324.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWQ0"	"PH-interacting protein OS=Homo sapiens OX=9606 GN=PHIP PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1821"	"206.6"	"8.85"	"774.30"	"6.42"	"2"	"2"	"cell organization and biogenesis;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00400, Pf00439"	"55023"	"ENSG00000146247"	"PHIP"	"A7J992; B2RPK4; hsa:55023; Q05CQ9; Q5VVH4; Q66I29; Q69YV1; Q8NBZ5; Q8WWQ0; Q96H52; Q96ME2; Q9H261"	""	"RHOBTB2 GTPase cycle"	"1"	"0"	"7.5"	"10.7"	"11.6"	"15.5"	"9.3"	"11.8"	"18.9"	"27.3"	"43.7"	"100.3"	"149.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVC6"	"Mediator of RNA polymerase II transcription subunit 17 OS=Homo sapiens OX=9606 GN=MED17 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"651"	"72.8"	"7.44"	"673.55"	"6.39"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf10156"	"9440"	"ENSG00000042429"	"MED17"	"B3KN07; hsa:9440; Q9HA81; Q9NVC6; Q9UNP7; Q9Y2W0; Q9Y660"	""	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Generic Transcription Pathway"	"3"	"0"	"14.9"	"14.0"	"27.1"	"20.3"	"17.7"	"16.8"	"38.6"	"40.1"	"47.6"	"128.2"	"197.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11532"	"Dystrophin OS=Homo sapiens OX=9606 GN=DMD PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"3685"	"426.5"	"5.88"	"523.47"	"6.39"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00397, Pf00435, Pf00569, Pf09068, Pf09069"	"1756"	"ENSG00000198947"	"DMD"	"A1L0U9; E7EQR9; E7EQS5; E7ESB2; E9PDN1; E9PDN5; F5GZY3; F8VX32; hsa:1756; P11532; Q02295; Q14169; Q14170; Q5JYU0; Q6NSJ9; Q7KZ48; Q8N754; Q9UCW3; Q9UCW4"	"Arrhythmogenic right ventricular cardiomyopathy; Ectoderm differentiation; Striated muscle contraction pathway; Acute viral myocarditis; Disturbed pathways in Duchenne Muscular Dystrophy; 13q12.12 copy number variation"	"Non-integrin membrane-ECM interactions; Striated Muscle Contraction"	"8"	"0"	"101.3"	"92.4"	"79.8"	"101.9"	"85.9"	"70.4"	"125.9"	"134.6"	"152.1"	"240.5"	"204.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00268"	"Transcription initiation factor TFIID subunit 4 OS=Homo sapiens OX=9606 GN=TAF4 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1085"	"110.0"	"9.94"	"814.54"	"6.36"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf05236, Pf07531"	"6874"	"ENSG00000130699"	"TAF4"	"A6NGD9; hsa:6874; O00268; Q5TBP6; Q99721; Q9BR40; Q9BX42"	""	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; Regulation of TP53 Activity through Phosphorylation; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"9"	"0"	"117.3"	"95.8"	"126.3"	"135.0"	"112.9"	"119.0"	"146.0"	"164.8"	"198.9"	"369.9"	"490.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6X4"	"Soluble lamin-associated protein of 75 kDa OS=Homo sapiens OX=9606 GN=FAM169A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"670"	"74.9"	"4.60"	"628.28"	"6.36"	"1"	"1"	""	"other membranes;nucleus"	""	""	"26049"	"ENSG00000198780"	"FAM169A"	"A8K1T9; hsa:26049; Q6MZT0; Q9H989; Q9Y6X4"	""	"RHOF GTPase cycle"	"1"	"0"	"51.1"	"41.2"	"57.7"	"60.7"	"45.9"	"49.7"	"72.4"	"63.7"	"91.5"	"181.6"	"289.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02447"	"Transcription factor Sp3 OS=Homo sapiens OX=9606 GN=SP3 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"781"	"81.9"	"5.26"	"599.81"	"6.36"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"6670"	"ENSG00000172845"	"SP3"	"A0AVL9; B4E2B7; hsa:6670; Q02447; Q69B26; Q69B27; Q8TD56; Q8WWU4; Q9BQR1"	"MECP2 and associated Rett syndrome; Non-genomic actions of 1,25 dihydroxyvitamin D3; Sudden infant death syndrome (SIDS) susceptibility pathways"	"SUMOylation of transcription factors"	"4"	"0"	"225.5"	"222.3"	"255.9"	"280.3"	"231.5"	"242.4"	"263.0"	"261.2"	"281.4"	"388.3"	"502.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRK5"	"45 kDa calcium-binding protein OS=Homo sapiens OX=9606 GN=SDF4 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"362"	"41.8"	"4.86"	"741.34"	"6.35"	"2"	"2"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13202, Pf13499"	"51150"	""	"SDF4"	"B1AME5; B1AME6; B2RDF1; B4DSM1; hsa:51150; Q53G52; Q53HQ9; Q8NBQ3; Q96AA1; Q9BRK5; Q9NZP7; Q9UN53"	""	""	"0"	"0"	"346.8"	"291.0"	"356.2"	"477.9"	"343.8"	"329.9"	"504.2"	"506.4"	"616.3"	"1012.4"	"1123.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYQ5"	"Microprocessor complex subunit DGCR8 OS=Homo sapiens OX=9606 GN=DGCR8 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"773"	"86.0"	"5.95"	"534.96"	"6.35"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035"	"54487"	"ENSG00000128191"	"DGCR8"	"B2R8G1; hsa:54487; Q6DCB2; Q6MZE9; Q6Y2L0; Q8WYQ5; Q96G39; Q96GP8; Q9H6L8; Q9H6T7; Q9NRW2"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; DDX1 as a regulatory component of the Drosha microprocessor; 22q11.2 copy number variation syndrome"	"Transcriptional Regulation by MECP2; MicroRNA (miRNA) biogenesis"	"6"	"0"	"47.0"	"54.0"	"50.5"	"73.2"	"48.2"	"50.4"	"76.6"	"88.6"	"105.2"	"208.0"	"258.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30085"	"UMP-CMP kinase OS=Homo sapiens OX=9606 GN=CMPK1 PE=1 SV=3"	"0.000"	""	"10"	"2"	"4"	"2"	"196"	"22.2"	"5.57"	"705.81"	"6.33"	"2"	"2"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"51727"	"ENSG00000162368"	"CMPK1"	"B2R6S5; B4DPU7; E9PGI8; hsa:51727; P30085; Q53GB7; Q5SVZ0; Q96C07; Q9UBQ8; Q9UIA2"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"85.2"	"94.6"	"118.3"	"148.1"	"82.4"	"84.6"	"136.3"	"162.7"	"175.4"	"667.7"	"1964.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4LE39"	"AT-rich interactive domain-containing protein 4B OS=Homo sapiens OX=9606 GN=ARID4B PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1312"	"147.7"	"5.12"	"612.27"	"6.33"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"nucleic acid binding activity"	"Pf01388, Pf08169, Pf11717"	"51742"	"ENSG00000054267"	"ARID4B"	"A1L465; hsa:51742; Q3MHV4; Q4LE39; Q5HY99; Q5T2C2; Q5T2C3; Q5T2C4; Q5T2C5; Q5T2C6; Q6P600; Q86UX1; Q86WR4; Q9H915; Q9NYU3; Q9NZB6; Q9NZG4; Q9P2W4; Q9UF62; Q9Y6E1"	"Pathways affected in adenoid cystic carcinoma"	"NoRC negatively regulates rRNA expression; Potential therapeutics for SARS; HDACs deacetylate histones"	"4"	"0"	"107.7"	"63.8"	"125.1"	"120.8"	"81.2"	"96.1"	"120.0"	"110.9"	"132.2"	"220.2"	"374.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MU7"	"YTH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=YTHDC1 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"727"	"84.6"	"6.23"	"290.74"	"6.32"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity"	"Pf04146"	"91746"	"ENSG00000083896; ENSG00000275272"	"YTHDC1"	"hsa:91746; Q4W5Q3; Q7Z622; Q8TF35; Q96MU7"	""	""	"0"	"0"	"68.5"	"66.1"	"84.4"	"93.6"	"71.6"	"74.3"	"113.5"	"106.9"	"146.1"	"258.1"	"331.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4D1"	"Disheveled-associated activator of morphogenesis 1 OS=Homo sapiens OX=9606 GN=DAAM1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"1078"	"123.4"	"7.23"	"768.15"	"6.31"	"2"	"2"	"cell-cell signaling;cell organization and biogenesis;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"23002"	"ENSG00000100592"	"DAAM1"	"hsa:23002; Q86U34; Q8N1Z8; Q8TB39; Q9Y4D1"	"Physico-chemical features and toxicity-associated pathways; Wnt signaling"	"RHO GTPases Activate Formins; PCP/CE pathway; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RHOB GTPase cycle"	"8"	"0"	"107.9"	"72.5"	"113.0"	"133.1"	"90.1"	"106.3"	"175.5"	"182.8"	"240.9"	"426.2"	"571.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14690"	"Protein RRP5 homolog OS=Homo sapiens OX=9606 GN=PDCD11 PE=1 SV=3"	"0.000"	""	"1"	"2"	"4"	"2"	"1871"	"208.6"	"8.87"	"640.35"	"6.30"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00575, Pf05843"	"22984"	"ENSG00000148843"	"PDCD11"	"hsa:22984; Q14690; Q2TA92; Q5W093; Q6P2J3; Q86VQ8; Q9H4P1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"22.4"	"25.7"	"28.0"	"36.7"	"26.5"	"25.0"	"42.2"	"47.9"	"63.4"	"130.6"	"188.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKN8"	"General transcription factor 3C polypeptide 4 OS=Homo sapiens OX=9606 GN=GTF3C4 PE=1 SV=2"	"0.001"	""	"4"	"3"	"3"	"3"	"822"	"91.9"	"6.65"	"238.10"	"6.30"	"1"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf12657, Pf12660, Pf19336"	"9329"	"ENSG00000125484"	"GTF3C4"	"hsa:9329; Q5VZJ7; Q9UKN8"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter"	"3"	"0"	"16.8"	"13.0"	"23.4"	"29.8"	"17.8"	"19.9"	"33.3"	"31.2"	"47.7"	"251.8"	"452.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTD8"	"RNA-binding protein 42 OS=Homo sapiens OX=9606 GN=RBM42 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"480"	"50.4"	"9.63"	"669.60"	"6.29"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"79171"	"ENSG00000126254"	"RBM42"	"hsa:79171; O00320; Q8N5R7; Q9BTD8; Q9BU66"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"168.9"	"186.8"	"146.7"	"214.1"	"117.4"	"137.4"	"212.3"	"226.2"	"281.4"	"776.4"	"888.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13825"	"Methylglutaconyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=AUH PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"339"	"35.6"	"9.48"	"776.89"	"6.29"	"2"	"2"	"other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00378"	"549"	"ENSG00000148090"	"AUH"	"B1ALV7; B1ALV8; hsa:549; Q13825; Q8WUE4"	"Amino acid metabolism"	"Branched-chain amino acid catabolism"	"2"	"0"	"242.5"	"220.0"	"255.9"	"268.2"	"219.3"	"234.7"	"232.1"	"232.1"	"210.3"	"271.0"	"270.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84090"	"Enhancer of rudimentary homolog OS=Homo sapiens OX=9606 GN=ERH PE=1 SV=1"	"0.000"	""	"17"	"2"	"4"	"2"	"104"	"12.3"	"5.92"	"533.43"	"6.29"	"2"	"2"	"cell cycle OR cell proliferation;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01133"	"2079"	"ENSG00000100632"	"ERH"	"B2R5H2; hsa:2079; P70659; P84090; Q14259"	""	""	"0"	"0"	"112.4"	"173.9"	"115.2"	"152.1"	"130.5"	"125.3"	"198.4"	"257.6"	"323.8"	"968.6"	"1321.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62829"	"60S ribosomal protein L23 OS=Homo sapiens OX=9606 GN=RPL23 PE=1 SV=1"	"0.000"	""	"19"	"3"	"5"	"3"	"140"	"14.9"	"10.51"	"1006.87"	"6.28"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00238"	"9349"	"ENSG00000125691"	"RPL23"	"hsa:9349; P23131; P24048; P62829; Q29246; Q3SWV7; Q6P5S1"	"Cytoplasmic ribosomal proteins; 17q12 copy number variation syndrome"	"Regulation of expression of SLITs and ROBOs; SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"685.2"	"665.1"	"744.0"	"958.5"	"612.1"	"547.1"	"943.7"	"951.0"	"1089.3"	"2212.9"	"2995.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P61923"	"Coatomer subunit zeta-1 OS=Homo sapiens OX=9606 GN=COPZ1 PE=1 SV=1"	""	""	"13"	"1"	"1"	"1"	"177"	"20.2"	"4.81"	""	"6.27"	""	"1"	"transport"	"other membranes;cytosol;ER/Golgi"	""	"Pf01217"	"22818"	"ENSG00000111481"	"COPZ1"	"B4DDX8; B4DHZ0; F8VS17; F8VWL5; hsa:22818; P61923; Q549N6; Q9Y3C3"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"26.8"	"19.6"	"26.2"	"31.5"	"17.7"	"16.7"	"31.6"	"33.0"	"48.1"	"96.9"	"115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46778"	"60S ribosomal protein L21 OS=Homo sapiens OX=9606 GN=RPL21 PE=1 SV=2"	"0.000"	""	"21"	"3"	"5"	"3"	"160"	"18.6"	"10.49"	"956.77"	"6.26"	"3"	"2"	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;other cell component"	"other molecular function"	"Pf01157"	"6144"	"ENSG00000122026"	"RPL21"	"hsa:6144; P46778; Q16699"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"437.0"	"445.0"	"571.5"	"687.6"	"459.3"	"468.2"	"723.5"	"765.0"	"879.2"	"1935.7"	"3118.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q70Z53"	"Protein FRA10AC1 OS=Homo sapiens OX=9606 GN=FRA10AC1 PE=1 SV=3"	"0.000"	""	"7"	"2"	"4"	"2"	"315"	"37.5"	"8.10"	"690.98"	"6.26"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf09725"	"118924"	"ENSG00000148690"	"FRA10AC1"	"C9JCR4; C9JCR5; C9JMY4; hsa:118924; Q70Z49; Q70Z50; Q70Z51; Q70Z52; Q70Z53; Q8N293; Q8WVH5; Q96JQ8"	""	""	"0"	"0"	"22.9"	"33.3"	"33.3"	"38.2"	"26.6"	"28.7"	"75.0"	"83.0"	"132.4"	"263.5"	"313.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IZ7"	"Serine/Arginine-related protein 53 OS=Homo sapiens OX=9606 GN=RSRC1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"334"	"38.7"	"11.08"	"590.88"	"6.25"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	""	""	"51319"	"ENSG00000174891"	"RSRC1"	"A8K2R9; hsa:51319; Q96IZ7; Q96QK2; Q9NZE5"	""	""	"0"	"0"	"52.4"	"50.2"	"52.1"	"76.1"	"45.2"	"59.9"	"70.5"	"76.7"	"102.2"	"219.4"	"336.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15345"	"Leucine-rich repeat-containing protein 41 OS=Homo sapiens OX=9606 GN=LRRC41 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"812"	"88.6"	"8.38"	"599.22"	"6.23"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	""	"10489"	"ENSG00000132128"	"LRRC41"	"A8K5G8; hsa:10489; Q15345; Q3MJ96; Q5TDF5; Q71RA8; Q9BSM0"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation; RHOBTB3 ATPase cycle"	"3"	"0"	"22.7"	"23.4"	"24.0"	"26.5"	"22.5"	"19.2"	"29.4"	"31.6"	"31.8"	"51.3"	"60.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H981"	"Actin-related protein 8 OS=Homo sapiens OX=9606 GN=ACTR8 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"624"	"70.4"	"7.78"	"1040.79"	"6.20"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00022"	"93973"	"ENSG00000113812"	"ACTR8"	"B3KSW7; hsa:93973; Q8N566; Q9H663; Q9H981"	""	"UCH proteinases; DNA Damage Recognition in GG-NER"	"2"	"0"	"11.8"	"5.8"	"11.9"	"11.2"	"9.0"	"7.3"	"18.4"	"23.1"	"39.7"	"126.6"	"176.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYR9"	"NF-kappa-B inhibitor-interacting Ras-like protein 2 OS=Homo sapiens OX=9606 GN=NKIRAS2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"4"	"1"	"191"	"21.5"	"8.05"	"647.88"	"6.20"	"1"	"1"	"stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00071"	"28511"	"ENSG00000168256"	"NKIRAS2"	"A6NCZ5; B3KNN0; B4DNM3; hsa:28511; Q6PK52; Q96KC7; Q9NSX1; Q9NYR9"	""	"RIP-mediated NFkB activation via ZBP1; TAK1-dependent IKK and NF-kappa-B activation  ; TRAF6 mediated NF-kB activation"	"3"	"0"	"46.2"	"44.6"	"51.0"	"57.7"	"47.3"	"56.2"	"147.6"	"158.1"	"220.2"	"459.4"	"537.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02040"	"A-kinase anchor protein 17A OS=Homo sapiens OX=9606 GN=AKAP17A PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"695"	"80.7"	"9.73"	"730.13"	"6.19"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus"	"other molecular function"	""	"8227"	"ENSG00000197976"	"AKAP17A"	"hsa:8227; Q02040; Q02832; Q2TB98; Q5JQ74; Q5JQ76; Q8N6U9"	""	""	"0"	"0"	"178.2"	"157.8"	"199.2"	"374.6"	"153.2"	"121.9"	"417.2"	"461.3"	"746.5"	"1449.2"	"1482.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JTJ3"	"Cytochrome c oxidase assembly factor 6 homolog OS=Homo sapiens OX=9606 GN=COA6 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"125"	"14.1"	"8.25"	"585.85"	"6.19"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf02297"	"388753"	"ENSG00000168275"	"COA6"	"hsa:388753; Q5JTJ2; Q5JTJ3; Q5JTJ4; Q8TA88"	"Mitochondrial complex IV assembly"	"Mitochondrial protein import"	"2"	"0"	"75.8"	"74.8"	"97.2"	"103.6"	"73.1"	"74.1"	"103.6"	"123.8"	"150.8"	"333.2"	"700.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXS6"	"Nucleolar and spindle-associated protein 1 OS=Homo sapiens OX=9606 GN=NUSAP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"441"	"49.4"	"9.91"	"602.95"	"6.18"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity"	"Pf16006"	"51203"	"ENSG00000137804"	"NUSAP1"	"B4DDF1; E7ERR5; hsa:51203; J3KN21; Q53GW2; Q8TBT4; Q96E58; Q96FJ1; Q9BXS6; Q9GZM9; Q9NZ85; Q9UI70"	""	""	"0"	"0"	"35.3"	"24.3"	"47.1"	"68.5"	"39.2"	"39.3"	"107.7"	"110.8"	"214.2"	"448.6"	"475.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95573"	"Long-chain-fatty-acid--CoA ligase 3 OS=Homo sapiens OX=9606 GN=ACSL3 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"1"	"720"	"80.4"	"8.38"	"615.42"	"6.16"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00501"	"2181"	"ENSG00000123983"	"ACSL3"	"hsa:2181; O95573; Q60I92; Q8IUM9"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Ferroptosis; Thermogenesis; Ciliary landscape; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Omega-3 / omega-6 fatty acid synthesis; Omega-9 fatty acid synthesis; Fatty acid transporters; Mitochondrial fatty acid oxidation disorders"	"Synthesis of very long-chain fatty acyl-CoAs; Intracellular metabolism of fatty acids regulates insulin secretion"	"14"	"1"	"74.9"	"84.5"	"63.9"	"92.7"	"62.7"	"65.2"	"126.8"	"155.1"	"233.7"	"496.7"	"545.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75334"	"Liprin-alpha-2 OS=Homo sapiens OX=9606 GN=PPFIA2 PE=1 SV=2"	"0.000"	""	"4"	"4"	"6"	"1"	"1257"	"143.2"	"6.11"	"1751.30"	"6.15"	"3"	"2"	"cell adhesion;cell organization and biogenesis;transport;other biological processes"	"cytosol;other cell component"	""	"Pf00536, Pf07647"	"8499"	"ENSG00000139220"	"PPFIA2"	"B3KVT5; B3KXA0; B7Z2A6; B7Z3U9; B7Z663; B7ZKZ5; E7ERB8; E7ETG6; F8VP68; hsa:8499; O75334; Q2M3G8"	""	"Glutamate Neurotransmitter Release Cycle; Serotonin Neurotransmitter Release Cycle; Norepinephrine Neurotransmitter Release Cycle; Dopamine Neurotransmitter Release Cycle; Acetylcholine Neurotransmitter Release Cycle; Receptor-type tyrosine-protein phosphatases"	"6"	"1"	"100.1"	"98.5"	"131.7"	"140.8"	"90.8"	"101.4"	"123.2"	"134.1"	"159.5"	"309.1"	"466.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y262"	"Eukaryotic translation initiation factor 3 subunit L OS=Homo sapiens OX=9606 GN=EIF3L PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"564"	"66.7"	"6.34"	"265.44"	"6.13"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf10255"	"51386"	"ENSG00000100129"	"EIF3L"	"B2RDG6; B4DYB2; G8JLH4; hsa:51386; Q53HQ1; Q53HT4; Q5QTR1; Q5TI15; Q6ICD2; Q9Y262"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"6"	"0"	"80.0"	"50.6"	"91.6"	"102.1"	"87.9"	"84.8"	"135.8"	"156.1"	"201.0"	"532.6"	"1343.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W92"	"Liprin-beta-1 OS=Homo sapiens OX=9606 GN=PPFIBP1 PE=1 SV=2"	"0.000"	""	"3"	"3"	"4"	"3"	"1011"	"114.0"	"5.55"	"579.37"	"6.12"	"2"	"2"	"cell adhesion;cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00536, Pf07647"	"8496"	"ENSG00000110841"	"PPFIBP1"	"hsa:8496; O75336; Q86W92; Q86X70; Q9NY03; Q9ULJ0"	""	"Signaling by ALK fusions and activated point mutants; Receptor-type tyrosine-protein phosphatases"	"2"	"0"	"141.3"	"127.8"	"138.1"	"164.9"	"130.6"	"126.9"	"196.7"	"203.0"	"216.3"	"396.4"	"411.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C57"	"Protein CUSTOS OS=Homo sapiens OX=9606 GN=CUSTOS PE=1 SV=2"	"0.000"	""	"17"	"3"	"4"	"3"	"262"	"28.2"	"9.42"	"1378.48"	"6.09"	"3"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"nucleus"	""	""	"64897"	"ENSG00000157895"	"CUSTOS"	"hsa:64897; Q53HF0; Q96C57; Q9H9Z7"	""	""	"0"	"0"	"111.3"	"99.1"	"120.9"	"140.0"	"115.1"	"111.3"	"165.9"	"182.5"	"261.0"	"538.2"	"649.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O15212"	"Prefoldin subunit 6 OS=Homo sapiens OX=9606 GN=PFDN6 PE=1 SV=1"	""	""	"16"	"2"	"2"	"2"	"129"	"14.6"	"8.88"	""	"6.07"	""	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"10471"	"ENSG00000204220; ENSG00000206283; ENSG00000224782; ENSG00000235692; ENSG00000237335"	"PFDN6"	"hsa:10471; O15212"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"70.8"	"54.7"	"83.5"	"131.8"	"66.2"	"63.4"	"135.3"	"165.1"	"253.1"	"880.2"	"1309.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42677"	"40S ribosomal protein S27 OS=Homo sapiens OX=9606 GN=RPS27 PE=1 SV=3"	"0.000"	""	"25"	"2"	"4"	"2"	"84"	"9.5"	"9.45"	"551.99"	"6.07"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01667"	"6232"	"ENSG00000177954"	"RPS27"	"hsa:6232; P42677; Q5T4L6"	"Cytoplasmic ribosomal proteins"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"25"	"0"	"167.3"	"184.7"	"178.0"	"211.8"	"162.2"	"129.8"	"251.4"	"281.3"	"340.6"	"655.7"	"849.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83881"	"60S ribosomal protein L36a OS=Homo sapiens OX=9606 GN=RPL36A PE=1 SV=2"	"0.000"	""	"16"	"2"	"3"	"2"	"106"	"12.4"	"10.58"	"303.67"	"6.05"	"1"	"2"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus"	"other molecular function"	"Pf00935"	"6173"	"ENSG00000241343"	"RPL36A"	"hsa:6173; P09896; P10661; P83881; Q08ES5; Q5J9I6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"365.0"	"343.9"	"482.6"	"644.2"	"420.2"	"342.3"	"680.2"	"662.2"	"773.8"	"1471.4"	"2125.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86T24"	"Transcriptional regulator Kaiso OS=Homo sapiens OX=9606 GN=ZBTB33 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"672"	"74.4"	"5.12"	"499.84"	"6.05"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00651"	"10009"	"ENSG00000177485"	"ZBTB33"	"B2R5U6; hsa:10009; O00319; Q7Z361; Q86T24; Q8IVP6; Q8N3P0"	"Wnt signaling pathway and pluripotency"	""	"1"	"0"	"79.2"	"74.2"	"90.8"	"114.2"	"77.7"	"73.9"	"104.8"	"108.3"	"134.3"	"195.5"	"236.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX63"	"MICOS complex subunit MIC19 OS=Homo sapiens OX=9606 GN=CHCHD3 PE=1 SV=1"	"0.000"	""	"8"	"2"	"4"	"2"	"227"	"26.1"	"8.28"	"700.32"	"6.05"	"2"	"2"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf05300"	"54927"	"ENSG00000106554"	"CHCHD3"	"hsa:54927; Q9NX63"	""	"Mitochondrial protein import; Cristae formation"	"2"	"0"	"51.4"	"47.3"	"81.2"	"87.5"	"55.0"	"56.8"	"96.3"	"105.7"	"137.8"	"342.5"	"526.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39880"	"Homeobox protein cut-like 1 OS=Homo sapiens OX=9606 GN=CUX1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1505"	"164.1"	"5.90"	"754.48"	"6.04"	"2"	"2"	"other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf02376"	"1523"	"ENSG00000257923"	"CUX1"	"B3KV79; J3KQV9; P39880; Q6NYH4; Q75LE5; Q75MT2; Q75MT3; Q86UJ7; Q9UEV5"	""	"Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"2"	"0"	"78.5"	"58.7"	"77.9"	"93.2"	"65.7"	"69.0"	"114.4"	"128.6"	"185.5"	"425.6"	"534.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13489"	"Ribonuclease inhibitor OS=Homo sapiens OX=9606 GN=RNH1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"461"	"49.9"	"4.82"	"640.34"	"6.03"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf13516, Pf18779"	"6050"	"ENSG00000023191; ENSG00000276230"	"RNH1"	"hsa:6050; P13489; Q8IZK8; Q96FD7; Q9BQ80; Q9UDK6"	""	""	"0"	"0"	"180.7"	"145.5"	"215.3"	"244.3"	"173.0"	"146.6"	"240.4"	"255.0"	"295.2"	"481.9"	"642.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99627"	"COP9 signalosome complex subunit 8 OS=Homo sapiens OX=9606 GN=COPS8 PE=1 SV=1"	"0.000"	""	"18"	"3"	"5"	"3"	"209"	"23.2"	"5.38"	"1122.52"	"6.03"	"2"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf10075"	"10920"	"ENSG00000198612"	"COPS8"	"A8K1H6; hsa:10920; Q53QS9; Q99627"	"Ciliary landscape; 2q37 copy number variation syndrome"	"Neddylation; DNA Damage Recognition in GG-NER; Cargo recognition for clathrin-mediated endocytosis; Formation of TC-NER Pre-Incision Complex"	"6"	"0"	"50.4"	"60.8"	"66.7"	"64.3"	"58.7"	"61.6"	"125.0"	"128.5"	"184.7"	"537.1"	"1004.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NW82"	"WD repeat-containing protein 70 OS=Homo sapiens OX=9606 GN=WDR70 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"654"	"73.2"	"6.33"	"739.93"	"6.02"	"2"	"2"	""	"nucleus;other cell component"	"other molecular function"	"Pf00400"	"55100"	"ENSG00000082068"	"WDR70"	"hsa:55100; Q9H053; Q9NW82"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"31.8"	"29.5"	"41.4"	"65.6"	"32.5"	"25.6"	"54.4"	"54.9"	"55.1"	"83.9"	"142.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82663"	"28S ribosomal protein S25, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS25 PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"2"	"173"	"20.1"	"8.82"	"519.58"	"6.02"	"2"	"2"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"64432"	"ENSG00000131368"	"MRPS25"	"B4DFJ5; B4DQG6; hsa:64432; P82663; Q9H7P5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"15.2"	"5.9"	"38.1"	"35.2"	"25.6"	"21.4"	"29.9"	"31.5"	"51.0"	"103.1"	"200.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15643"	"Thyroid receptor-interacting protein 11 OS=Homo sapiens OX=9606 GN=TRIP11 PE=1 SV=3"	"0.000"	""	"1"	"3"	"5"	"1"	"1979"	"227.4"	"5.26"	"855.22"	"6.02"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;cytoskeleton;ER/Golgi"	"other molecular function"	""	"9321"	"ENSG00000100815"	"TRIP11"	"B2RUT2; hsa:9321; O14689; O15154; O95949; Q15643; Q6MZL5"	""	"Intraflagellar transport; Intra-Golgi traffic; Signaling by FLT3 fusion proteins"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5B9"	"FACT complex subunit SPT16 OS=Homo sapiens OX=9606 GN=SUPT16H PE=1 SV=1"	"0.000"	""	"2"	"2"	"4"	"2"	"1047"	"119.8"	"5.66"	"642.82"	"6.01"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00557, Pf08512, Pf08644, Pf14826"	"11198"	"ENSG00000092201"	"SUPT16H"	"hsa:11198; Q6GMT8; Q6P2F1; Q6PJM1; Q9NRX0; Q9Y5B9"	""	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation"	"12"	"0"	"96.4"	"100.5"	"98.9"	"119.9"	"83.1"	"94.8"	"166.7"	"188.6"	"226.4"	"552.4"	"945.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZS3"	"WD repeat-containing protein 61 OS=Homo sapiens OX=9606 GN=WDR61 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"305"	"33.6"	"5.47"	"343.48"	"6.01"	"1"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00400"	"80349"	"ENSG00000140395"	"SKIC8"	"D3DW84; hsa:80349; Q6IA22; Q7Z4X4; Q9GZS3"	""	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins; mRNA decay by 3' to 5' exoribonuclease"	"5"	"0"	"174.6"	"147.1"	"190.7"	"197.3"	"156.8"	"148.2"	"229.2"	"244.2"	"291.6"	"858.3"	"1237.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43242"	"26S proteasome non-ATPase regulatory subunit 3 OS=Homo sapiens OX=9606 GN=PSMD3 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"534"	"60.9"	"8.44"	""	"6.01"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01399, Pf08375"	"5709"	"ENSG00000108344"	"PSMD3"	"B3KMW9; B4DT72; hsa:5709; O43242; Q96EI2; Q9BQA4"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"16.3"	"8.2"	"16.5"	"25.0"	"11.4"	"15.3"	"23.8"	"24.1"	"34.4"	"111.3"	"169.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49642"	"DNA primase small subunit OS=Homo sapiens OX=9606 GN=PRIM1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"420"	"49.9"	"8.21"	"728.52"	"6.01"	"2"	"2"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01896"	"5557"	"ENSG00000198056"	"PRIM1"	"hsa:5557; P49642"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Activation of the pre-replicative complex; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Telomere C-strand synthesis initiation; DNA replication initiation"	"13"	"0"	"104.1"	"107.6"	"126.4"	"170.9"	"114.1"	"124.3"	"216.0"	"209.4"	"349.7"	"1663.3"	"2132.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00442"	"RNA 3'-terminal phosphate cyclase OS=Homo sapiens OX=9606 GN=RTCA PE=1 SV=1"	"0.000"	""	"3"	"1"	"4"	"1"	"366"	"39.3"	"7.85"	"510.59"	"6.00"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf01137, Pf05189"	"8634"	"ENSG00000137996"	"RTCA"	"hsa:8634; O00442; Q5VVL5; Q5VVL6; Q96E99"	""	""	"0"	"0"	"21.0"	"21.2"	"28.8"	"31.2"	"26.4"	"21.0"	"50.7"	"58.2"	"81.1"	"272.2"	"398.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96RS0"	"Trimethylguanosine synthase OS=Homo sapiens OX=9606 GN=TGS1 PE=1 SV=3"	""	""	"3"	"1"	"2"	"1"	"853"	"96.6"	"4.94"	""	"5.99"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf09445"	"96764"	"ENSG00000137574"	"TGS1"	"A6NJQ5; hsa:96764; Q5GH23; Q8TDG9; Q96QU3; Q96RS0; Q9H5V3"	""	"Transcriptional regulation of white adipocyte differentiation; snRNP Assembly; PPARA activates gene expression; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); RORA activates gene expression"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08397"	"Porphobilinogen deaminase OS=Homo sapiens OX=9606 GN=HMBS PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"361"	"39.3"	"7.18"	"596.67"	"5.97"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01379, Pf03900"	"3145"	"ENSG00000256269"	"HMBS"	"A8K2L0; G3V1P4; G5EA58; hsa:3145; P08396; P08397; Q16012"	"Hemesynthesis defects and porphyrias; Heme biosynthesis"	"Heme biosynthesis"	"3"	"0"	"3.6"	"3.4"	"5.7"	"9.3"	"6.3"	"4.4"	"11.2"	"9.3"	"13.3"	"50.9"	"88.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62879"	"Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2 OS=Homo sapiens OX=9606 GN=GNB2 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"340"	"37.3"	"6.00"	"486.15"	"5.97"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"2783"	"ENSG00000172354"	"GNB2"	"B3KPU1; hsa:2783; P11016; P54312; P62879"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"G alpha (i) signalling events; G alpha (12/13) signalling events; G alpha (q) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"36"	"0"	"15.3"	"13.6"	"16.8"	"22.9"	"11.4"	"11.8"	"37.0"	"35.9"	"63.5"	"351.8"	"596.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14727"	"Apoptotic protease-activating factor 1 OS=Homo sapiens OX=9606 GN=APAF1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"1248"	"141.7"	"6.40"	"704.54"	"5.96"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400, Pf00619, Pf00931, Pf17908"	"317"	"ENSG00000120868"	"APAF1"	"B2RMX8; hsa:317; O14727; O43297; Q7Z438; Q9BXZ6; Q9UBZ5; Q9UGN8; Q9UGN9; Q9UGP0; Q9UJ58; Q9UJ59; Q9UJ60; Q9UJ61; Q9UJ62; Q9UJ63; Q9UJ64; Q9UJ65; Q9UJ66; Q9UJ67; Q9UNC9"	"miRNA regulation of DNA damage response; Alzheimer's disease and miRNA effects; TNF-alpha signaling pathway; Parkinson's disease pathway; Amyotrophic lateral sclerosis (ALS); Nanomaterial induced apoptosis; Apoptosis; Fas ligand pathway and stress induction of heat shock proteins; Apoptosis modulation by HSP70; Oxidative damage response; miRNA regulation of p53 pathway in prostate cancer; Measles virus infection; Small cell lung cancer; Hepatitis B infection; Regucalcin in proximal tubule epithelial kidney cells; Host-pathogen interaction of human coronaviruses - apoptosis; p53 transcriptional gene network; Complement system in neuronal development and plasticity; Alzheimer's disease; CKAP4 signaling pathway map; DNA damage response"	"Neutrophil degranulation; Transcriptional Regulation by E2F6; Activation of caspases through apoptosome-mediated cleavage; SMAC (DIABLO) binds to IAPs ; SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes ; TP53 Regulates Transcription of Caspase Activators and Caspases; Regulation of the apoptosome activity"	"29"	"0"	"0.0"	"0.0"	"2.0"	"0.0"	"0.0"	"2.1"	"10.0"	"11.0"	"29.7"	"116.0"	"180.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A5PLN9"	"Trafficking protein particle complex subunit 13 OS=Homo sapiens OX=9606 GN=TRAPPC13 PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"417"	"46.5"	"5.60"	"834.31"	"5.96"	"2"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf06159"	"80006"	"ENSG00000113597"	"TRAPPC13"	"A5PLN9; hsa:80006; Q17RZ9; Q49A23; Q4JHG0; Q6MZG4; Q8TCM2; Q9H8I3"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"12.3"	"10.0"	"16.2"	"17.3"	"11.6"	"11.4"	"55.2"	"68.1"	"110.4"	"289.6"	"464.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19784"	"Casein kinase II subunit alpha' OS=Homo sapiens OX=9606 GN=CSNK2A2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"350"	"41.2"	"8.56"	"649.08"	"5.94"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1459"	"ENSG00000070770"	"CSNK2A2"	"hsa:1459; P19784"	"Alzheimer's disease and miRNA effects; Allograft rejection; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Measles virus infection; Pleural mesothelioma; Alzheimer's disease"	"Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of TP53 Activity through Phosphorylation; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; WNT mediated activation of DVL; Signal transduction by L1; Receptor Mediated Mitophagy; Condensation of Prometaphase Chromosomes; Synthesis of PC"	"19"	"0"	"106.3"	"116.6"	"97.9"	"129.1"	"94.6"	"108.3"	"183.7"	"185.1"	"230.0"	"657.3"	"946.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L9L4"	"MOB kinase activator 1B OS=Homo sapiens OX=9606 GN=MOB1B PE=1 SV=3"	"0.000"	""	"15"	"2"	"3"	"2"	"216"	"25.1"	"6.73"	"314.00"	"5.94"	"1"	"2"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03637"	"92597"	"ENSG00000173542"	"MOB1B"	"B2R8U6; B4DRY3; hsa:92597; Q7L9L4; Q8IY23"	"Pleural mesothelioma"	"Signaling by Hippo"	"2"	"0"	"18.5"	"14.5"	"24.2"	"24.0"	"13.5"	"20.2"	"29.4"	"30.9"	"55.5"	"185.3"	"270.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P07858"	"Cathepsin B OS=Homo sapiens OX=9606 GN=CTSB PE=1 SV=3"	""	""	"7"	"1"	"1"	"1"	"339"	"37.8"	"6.30"	""	"5.94"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00112, Pf08127"	"1508"	"ENSG00000164733; ENSG00000285132"	"CTSB"	"B3KQR5; B3KRR5; hsa:1508; P07858; Q503A6; Q96D87"	"Ebola virus infection in host; 8p23.1 copy number variation syndrome"	"Neutrophil degranulation; MHC class II antigen presentation; Collagen degradation; Assembly of collagen fibrils and other multimeric structures; Trafficking and processing of endosomal TLR"	"7"	"0"	"9.4"	"7.7"	"14.6"	"15.7"	"9.7"	"16.3"	"16.5"	"22.7"	"37.7"	"103.5"	"206.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96J01"	"THO complex subunit 3 OS=Homo sapiens OX=9606 GN=THOC3 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"351"	"38.7"	"6.09"	"693.41"	"5.93"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00400, Pf08662, Pf12894"	"84321"	"ENSG00000051596"	"THOC3"	"hsa:84321; Q6NZ53; Q96J01"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	"258.9"	"196.3"	"286.2"	"364.3"	"250.4"	"248.9"	"393.2"	"413.9"	"481.3"	"1020.9"	"1601.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7B2"	"Ribosome production factor 2 homolog OS=Homo sapiens OX=9606 GN=RPF2 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"306"	"35.6"	"9.99"	"591.17"	"5.92"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf04427"	"84154"	"ENSG00000197498"	"RPF2"	"hsa:84154; Q5VXN1; Q8N4A1; Q9H7B2"	""	""	"0"	"0"	"55.0"	"35.6"	"62.9"	"86.5"	"68.0"	"57.1"	"90.9"	"92.0"	"102.2"	"205.4"	"381.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92616"	"eIF-2-alpha kinase activator GCN1 OS=Homo sapiens OX=9606 GN=GCN1 PE=1 SV=6"	"0.000"	""	"1"	"2"	"4"	"2"	"2671"	"292.6"	"7.47"	"677.48"	"5.92"	"2"	"2"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"15.6"	"13.4"	"14.5"	"18.4"	"15.7"	"11.2"	"26.1"	"27.3"	"55.3"	"122.1"	"137.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20585"	"DNA mismatch repair protein Msh3 OS=Homo sapiens OX=9606 GN=MSH3 PE=1 SV=4"	"0.000"	""	"3"	"3"	"5"	"3"	"1137"	"127.3"	"8.02"	"1293.64"	"5.92"	"3"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00488, Pf01624, Pf05188, Pf05192"	"4437"	"ENSG00000113318"	"MSH3"	"A1L480; A1L482; A6NMM6; hsa:4437; P20585; Q6PJT5; Q86UQ6; Q92867"	"Chromosomal and microsatellite instability in colorectal cancer ; DNA repair pathways, full network"	"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta); Defective Mismatch Repair Associated With MSH3; Defective Mismatch Repair Associated With MSH2"	"5"	"0"	"41.3"	"52.2"	"36.6"	"59.3"	"37.1"	"41.8"	"62.9"	"59.8"	"93.0"	"177.8"	"219.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9T3"	"Elongator complex protein 3 OS=Homo sapiens OX=9606 GN=ELP3 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"547"	"62.2"	"8.88"	"634.52"	"5.92"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00583, Pf04055, Pf16199"	"55140"	"ENSG00000134014"	"ELP3"	"B4DE19; B4DIG1; E2QRI5; hsa:55140; Q53G84; Q6AWB0; Q9BVF7; Q9H9T3; Q9NVZ1"	"Ethanol effects on histone modifications"	"HATs acetylate histones"	"2"	"0"	"23.8"	"27.8"	"33.7"	"35.0"	"33.7"	"24.6"	"39.3"	"49.7"	"64.0"	"320.9"	"593.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13617"	"Cullin-2 OS=Homo sapiens OX=9606 GN=CUL2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"745"	"86.9"	"6.92"	"808.28"	"5.91"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00888, Pf10557"	"8453"	"ENSG00000108094"	"CUL2"	"B3KT95; B7Z6K8; D3DRY6; G3V1S2; hsa:8453; O00200; Q13617; Q5T2B6; Q9UNF9"	"Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"Regulation of expression of SLITs and ROBOs; Neddylation; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha"	"6"	"0"	"32.1"	"30.6"	"51.2"	"59.6"	"39.6"	"37.9"	"84.9"	"71.1"	"130.3"	"453.7"	"778.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NMY6"	"Putative annexin A2-like protein OS=Homo sapiens OX=9606 GN=ANXA2P2 PE=5 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"339"	"38.6"	"6.95"	"691.58"	"5.89"	"2"	"2"	"transport"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;nucleus;other cell component"	"transporter activity;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00191"	""	""	"ANXA2P2"	"A6NMY6"	""	""	"0"	"0"	"67.5"	"74.4"	"211.9"	"134.3"	"48.9"	"60.5"	"111.3"	"124.3"	"160.4"	"384.5"	"639.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52815"	"39S ribosomal protein L12, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL12 PE=1 SV=2"	"0.000"	""	"12"	"3"	"5"	"3"	"198"	"21.3"	"8.87"	"1067.33"	"5.89"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00542, Pf16320"	"6182"	"ENSG00000262814"	"MRPL12"	"hsa:6182; P52815; Q969U0; Q9HCA2; Q9UQJ3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"96.5"	"68.2"	"137.1"	"183.9"	"100.1"	"110.2"	"166.0"	"190.0"	"268.2"	"601.9"	"1018.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92925"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2 OS=Homo sapiens OX=9606 GN=SMARCD2 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"531"	"58.9"	"9.64"	"482.03"	"5.89"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf02201"	"6603"	"ENSG00000108604"	"SMARCD2"	"A5PLL5; A6NNQ7; B4DV56; B4E1R6; hsa:6603; Q7L2I6; Q92925; Q9UHZ1"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"0"	"16.7"	"16.4"	"16.5"	"21.8"	"16.6"	"14.8"	"22.2"	"26.4"	"34.6"	"129.8"	"197.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXQ4"	"GPALPP motifs-containing protein 1 OS=Homo sapiens OX=9606 GN=GPALPP1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"4"	"2"	"340"	"38.1"	"5.41"	"602.18"	"5.88"	"2"	"2"	""	""	""	"Pf12572"	"55425"	"ENSG00000133114"	"GPALPP1"	"A8K8X8; hsa:55425; Q05BX8; Q05D87; Q5T3Z3; Q5T3Z5; Q8IXQ4; Q9C0F9; Q9H2R0; Q9P0W6"	""	""	"0"	"0"	"134.3"	"104.9"	"155.1"	"152.8"	"136.5"	"142.2"	"170.3"	"178.2"	"198.3"	"301.6"	"401.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NV88"	"Integrator complex subunit 9 OS=Homo sapiens OX=9606 GN=INTS9 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"658"	"73.8"	"6.33"	""	"5.88"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	""	"Pf16661"	"55756"	"ENSG00000104299"	"INTS9"	"B7Z560; B7Z6M5; hsa:55756; O00224; Q8TB16; Q9NV88"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"19.5"	"15.6"	"21.5"	"27.0"	"18.4"	"11.1"	"27.2"	"39.0"	"41.7"	"82.4"	"108.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04844"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 OS=Homo sapiens OX=9606 GN=RPN2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"631"	"69.2"	"5.69"	"585.58"	"5.87"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;ER/Golgi;nucleus;other cytoplasmic organelle"	"translation activity"	"Pf05817"	"6185"	"ENSG00000118705"	"RPN2"	"hsa:6185; P04844; Q5JYR6; Q6IBA5; Q96E21; Q9BUQ3; Q9UBE1"	"Proteasome degradation; N-glycan biosynthesis"	"SRP-dependent cotranslational protein targeting to membrane; Asparagine N-linked glycosylation; Maturation of spike protein"	"5"	"0"	"8.1"	"6.7"	"14.2"	"15.7"	"9.0"	"11.1"	"24.5"	"23.3"	"51.8"	"155.4"	"293.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z460"	"CLIP-associating protein 1 OS=Homo sapiens OX=9606 GN=CLASP1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"1"	"1538"	"169.3"	"9.03"	"312.42"	"5.87"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02985, Pf12348"	"23332"	"ENSG00000074054"	"CLASP1"	"A2RU21; B7ZLX3; F5GWS0; hsa:23332; O75118; Q2KHQ9; Q5H9P0; Q7Z460; Q8N5B8; Q9BQT5"	"Microtubule cytoskeleton regulation; Splicing factor NOVA regulated synaptic proteins; 7q11.23 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; Role of ABL in ROBO-SLIT signaling"	"17"	"0"	"7.8"	"11.7"	"3.5"	"3.6"	"4.7"	"4.4"	"4.9"	"11.1"	"10.5"	"39.1"	"39.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y333"	"U6 snRNA-associated Sm-like protein LSm2 OS=Homo sapiens OX=9606 GN=LSM2 PE=1 SV=1"	"0.000"	""	"16"	"2"	"4"	"2"	"95"	"10.8"	"6.52"	"683.81"	"5.87"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01423"	"57819"	"ENSG00000172850; ENSG00000204392; ENSG00000224979; ENSG00000225998; ENSG00000231502; ENSG00000236826"	"LSM2"	"hsa:57819; Q6FGG1; Q9Y333"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA decay by 5' to 3' exoribonuclease"	"3"	"0"	"133.0"	"144.6"	"164.1"	"229.1"	"117.9"	"129.6"	"199.9"	"206.1"	"253.5"	"809.8"	"1738.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVC5"	"Ashwin OS=Homo sapiens OX=9606 GN=C2orf49 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"232"	"25.8"	"9.74"	"561.43"	"5.87"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"nucleus;other cell component"	""	"Pf15323"	"79074"	"ENSG00000135974"	"C2orf49"	"B3KXN3; B4E2G9; hsa:79074; Q9BVC5"	""	"tRNA processing in the nucleus"	"1"	"0"	"56.4"	"50.3"	"60.9"	"71.2"	"56.2"	"60.5"	"79.6"	"87.2"	"100.2"	"201.2"	"300.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GS7"	"Nucleoporin GLE1 OS=Homo sapiens OX=9606 GN=GLE1 PE=1 SV=2"	"0.000"	""	"8"	"3"	"3"	"3"	"698"	"79.8"	"7.43"	"448.63"	"5.86"	"1"	"2"	"other metabolic processes;transport"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07817"	"2733"	"ENSG00000119392"	"GLE1"	"hsa:2733; O75458; Q53GS7; Q53GT9; Q5VVU1; Q8NCP6; Q9UFL6"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript"	"1"	"0"	"46.5"	"50.4"	"68.5"	"82.3"	"53.7"	"50.3"	"99.4"	"102.3"	"143.4"	"375.3"	"485.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31483"	"Nucleolysin TIA-1 isoform p40 OS=Homo sapiens OX=9606 GN=TIA1 PE=1 SV=3"	"0.000"	""	"5"	"2"	"4"	"1"	"386"	"42.9"	"7.74"	"554.35"	"5.86"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"7072"	"ENSG00000116001"	"TIA1"	"hsa:7072; P31483; Q53SS9; Q96B58"	""	"FGFR2 alternative splicing"	"1"	"0"	"189.6"	"183.8"	"185.2"	"216.7"	"155.2"	"194.5"	"216.2"	"213.1"	"227.8"	"255.5"	"282.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23786"	"Carnitine O-palmitoyltransferase 2, mitochondrial OS=Homo sapiens OX=9606 GN=CPT2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"658"	"73.7"	"8.18"	"698.50"	"5.84"	"2"	"2"	"other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00755"	"1376"	"ENSG00000157184"	"CPT2"	"B2R6S0; hsa:1376; P23786; Q5SW68; Q9BQ26"	"Fatty acid beta-oxidation; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; PPAR signaling pathway; Thermogenesis; Mitochondrial fatty acid oxidation disorders"	"PPARA activates gene expression; Carnitine metabolism"	"9"	"0"	"20.3"	"15.4"	"16.2"	"18.7"	"20.0"	"18.5"	"36.0"	"29.0"	"37.9"	"89.7"	"150.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8ND04"	"Protein SMG8 OS=Homo sapiens OX=9606 GN=SMG8 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"991"	"109.6"	"7.68"	"583.39"	"5.84"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol"	""	"Pf10220"	"55181"	"ENSG00000167447"	"SMG8"	"hsa:55181; Q8N5U5; Q8ND04; Q8TDN0; Q9H5P5; Q9NVQ1"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	"16.2"	"3.0"	"17.5"	"18.8"	"12.9"	"15.6"	"16.1"	"20.2"	"20.8"	"21.9"	"37.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20962"	"Parathymosin OS=Homo sapiens OX=9606 GN=PTMS PE=1 SV=2"	"0.000"	""	"11"	"1"	"4"	"1"	"102"	"11.5"	"4.16"	"820.16"	"5.84"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf03247"	"5763"	"ENSG00000159335"	"PTMS"	"hsa:5763; P20962"	"IL-18 signaling pathway"	""	"1"	"0"	"244.6"	"195.2"	"215.3"	"245.2"	"224.1"	"224.8"	"247.4"	"222.7"	"228.1"	"271.6"	"281.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3X0"	"Coiled-coil domain-containing protein 9 OS=Homo sapiens OX=9606 GN=CCDC9 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"531"	"59.7"	"5.40"	"589.54"	"5.83"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity"	"Pf15266"	"26093"	"ENSG00000105321"	"CCDC9"	"hsa:26093; Q9Y3X0"	"IL-18 signaling pathway"	""	"1"	"0"	"6.3"	"11.8"	"14.5"	"19.0"	"9.2"	"12.1"	"17.2"	"15.6"	"23.3"	"80.6"	"107.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UER7"	"Death domain-associated protein 6 OS=Homo sapiens OX=9606 GN=DAXX PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"740"	"81.3"	"4.87"	"572.99"	"5.83"	"2"	"2"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03344"	"1616"	"ENSG00000204209; ENSG00000206206; ENSG00000206279; ENSG00000227046; ENSG00000231617"	"DAXX"	"B4E1I3; F5ANJ6; F5ANJ7; F5H082; hsa:1616; O14747; O15141; O15208; Q5STK9; Q9BWI3; Q9UER7"	"Androgen receptor signaling pathway; Amyotrophic lateral sclerosis (ALS); Fas ligand pathway and stress induction of heat shock proteins; MAPK signaling pathway; p38 MAPK signaling pathway"	"HCMV Early Events; Inhibition of DNA recombination at telomere; SUMOylation of transcription cofactors; Regulation of TP53 Degradation; Defective Inhibition of DNA Recombination at Telomere Due to DAXX Mutations; Defective Inhibition of DNA Recombination at Telomere Due to ATRX Mutations"	"11"	"0"	"35.3"	"31.7"	"46.2"	"40.0"	"31.0"	"33.6"	"77.4"	"84.2"	"98.2"	"191.2"	"224.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2K8"	"Serine/threonine-protein kinase TAO3 OS=Homo sapiens OX=9606 GN=TAOK3 PE=1 SV=2"	"0.000"	""	"2"	"2"	"4"	"2"	"898"	"105.3"	"7.30"	"631.47"	"5.83"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069"	"51347"	"ENSG00000135090"	"TAOK3"	"hsa:51347; Q658N1; Q8IUM4; Q9H2K8; Q9HC79; Q9NZM9; Q9UHG7"	"MAPK signaling pathway"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle"	"4"	"0"	"36.3"	"27.3"	"40.0"	"54.1"	"31.3"	"35.2"	"99.3"	"102.9"	"155.4"	"242.7"	"264.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NTX5"	"Ethylmalonyl-CoA decarboxylase OS=Homo sapiens OX=9606 GN=ECHDC1 PE=1 SV=2"	"0.001"	""	"4"	"1"	"3"	"1"	"307"	"33.7"	"8.21"	"235.53"	"5.82"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00378"	"55862"	"ENSG00000093144"	"ECHDC1"	"A6NFJ5; B7Z8S0; E9PEN7; E9PR31; F8W851; hsa:55862; Q5TEF6; Q5TEF7; Q5TEG0; Q5TEG4; Q9NTX5; Q9NZ30; V9HW18"	"Fatty acid biosynthesis"	""	"1"	"0"	"26.7"	"25.1"	"32.5"	"52.6"	"25.0"	"25.9"	"125.1"	"138.5"	"224.2"	"577.4"	"764.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IQ49"	"Replication stress response regulator SDE2 OS=Homo sapiens OX=9606 GN=SDE2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"451"	"49.7"	"6.05"	"622.17"	"5.82"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf13019, Pf13297"	"163859"	"ENSG00000143751"	"SDE2"	"A8K4P3; hsa:163859; Q5TD36; Q6IQ49; Q6ZS26; Q8NAG7"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"389.2"	"334.7"	"476.7"	"465.2"	"315.1"	"311.4"	"499.9"	"513.3"	"600.0"	"1210.8"	"1431.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P83876"	"Thioredoxin-like protein 4A OS=Homo sapiens OX=9606 GN=TXNL4A PE=1 SV=1"	"0.000"	""	"14"	"1"	"2"	"1"	"142"	"16.8"	"5.85"	"704.04"	"5.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;nucleus"	""	"Pf02966"	"10907"	"ENSG00000141759"	"TXNL4A"	"B2RC18; hsa:10907; O14834; P83876"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"56.8"	"58.0"	"44.5"	"60.4"	"38.7"	"49.0"	"64.0"	"57.3"	"70.0"	"123.5"	"209.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WR7"	"Proline and serine-rich protein 2 OS=Homo sapiens OX=9606 GN=PROSER2 PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"435"	"45.8"	"7.20"	"817.01"	"5.81"	"2"	"2"	""	""	""	"Pf15385"	"254427"	"ENSG00000148426"	"PROSER2"	"D3DRR8; hsa:254427; Q5W0J9; Q5W0K0; Q5W0K1; Q5W0K2; Q6PJC8; Q86WR7; Q8N317"	""	""	"0"	"0"	"18.9"	"13.2"	"14.4"	"17.7"	"16.6"	"11.0"	"21.1"	"24.4"	"27.5"	"68.0"	"43.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5SNT2"	"Transmembrane protein 201 OS=Homo sapiens OX=9606 GN=TMEM201 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"666"	"72.2"	"9.22"	""	"5.81"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf09779, Pf10476"	"199953"	"ENSG00000188807"	"TMEM201"	"B9EH90; hsa:199953; Q5SNT2; Q5SNT3"	""	""	"0"	"0"	"45.0"	"67.1"	"57.0"	"96.9"	"62.2"	"24.2"	"149.6"	"168.8"	"260.4"	"672.4"	"928.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54132"	"Bloom syndrome protein OS=Homo sapiens OX=9606 GN=BLM PE=1 SV=1"	"0.000"	""	"1"	"2"	"4"	"2"	"1417"	"158.9"	"7.49"	"685.49"	"5.81"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00570, Pf08072, Pf09382, Pf16124, Pf16202, Pf16204"	"641"	"ENSG00000197299"	"BLM"	"hsa:641; P54132; Q52M96"	"Primary ovarian insufficiency"	"Resolution of D-loop Structures through Holliday Junction Intermediates; SUMOylation of DNA damage response and repair proteins; Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Processive synthesis on the C-strand of the telomere"	"18"	"0"	"264.8"	"206.7"	"265.9"	"313.7"	"226.4"	"238.1"	"351.3"	"372.2"	"428.7"	"793.8"	"904.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15013"	"Rho guanine nucleotide exchange factor 10 OS=Homo sapiens OX=9606 GN=ARHGEF10 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1369"	"151.5"	"5.68"	"405.22"	"5.80"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton"	"enzyme regulator activity;cytoskeletal activity"	"Pf00621, Pf19056, Pf19057"	"9639"	"ENSG00000104728; ENSG00000274726"	"ARHGEF10"	"hsa:9639; O14665; O15013; Q2KHR8; Q68D55; Q8IWD9; Q8IY77"	""	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOB GTPase cycle"	"7"	"0"	"6.6"	"6.2"	"6.0"	"11.4"	"7.2"	"7.3"	"22.2"	"25.2"	"36.8"	"114.3"	"185.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHB9"	"Signal recognition particle subunit SRP68 OS=Homo sapiens OX=9606 GN=SRP68 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"627"	"70.7"	"8.56"	"611.85"	"5.80"	"2"	"2"	"transport;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf16969"	"6730"	"ENSG00000167881"	"SRP68"	"B3KUU5; B3KWY7; G3V1U4; hsa:6730; Q8NCJ4; Q8WUK2; Q9UHB9"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"88.8"	"89.4"	"85.6"	"116.3"	"81.2"	"75.9"	"154.5"	"171.4"	"223.5"	"631.8"	"1174.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVC3"	"Sister chromatid cohesion protein DCC1 OS=Homo sapiens OX=9606 GN=DSCC1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"4"	"2"	"393"	"44.8"	"5.17"	"555.24"	"5.79"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09724"	"79075"	"ENSG00000136982"	"DSCC1"	"hsa:79075; Q969N5; Q9BVC3"	"Gastric cancer network 2"	"Polymerase switching on the C-strand of the telomere"	"2"	"0"	"10.6"	"19.6"	"19.8"	"21.3"	"12.8"	"10.6"	"27.8"	"20.5"	"33.5"	"219.1"	"375.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BX40"	"Protein LSM14 homolog B OS=Homo sapiens OX=9606 GN=LSM14B PE=1 SV=1"	"0.000"	""	"10"	"3"	"4"	"2"	"385"	"42.0"	"9.69"	"495.70"	"5.78"	"2"	"2"	"other biological processes"	"other cell component"	"nucleic acid binding activity"	"Pf09532, Pf12701"	"149986"	"ENSG00000149657"	"LSM14B"	"hsa:149986; Q6PFW8; Q96LH8; Q9BX40"	""	""	"0"	"0"	"100.8"	"88.0"	"95.7"	"112.9"	"85.6"	"92.3"	"157.0"	"143.0"	"193.4"	"396.9"	"580.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRF8"	"CTP synthase 2 OS=Homo sapiens OX=9606 GN=CTPS2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"586"	"65.6"	"6.90"	"618.32"	"5.74"	"2"	"2"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00117, Pf06418"	"56474"	"ENSG00000047230"	"CTPS2"	"B3KWM2; hsa:56474; Q9BRI0; Q9H809; Q9H8K9; Q9NRF8"	"Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"41.1"	"34.7"	"42.8"	"54.9"	"47.6"	"34.8"	"71.6"	"71.3"	"126.9"	"429.3"	"637.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14174"	"Macrophage migration inhibitory factor OS=Homo sapiens OX=9606 GN=MIF PE=1 SV=4"	"0.000"	""	"8"	"1"	"4"	"1"	"115"	"12.5"	"7.88"	"664.27"	"5.73"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"4282"	"ENSG00000240972; ENSG00000276701"	"MIF"	"A5Z1R8; B2R4S3; hsa:4282; P14174; Q2V4Y5; Q6FHV0"	"Adipogenesis; Spinal cord injury"	"Neutrophil degranulation; Cell surface interactions at the vascular wall; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"5"	"0"	"194.4"	"214.8"	"343.3"	"953.6"	"208.3"	"161.2"	"499.8"	"529.6"	"592.7"	"1123.6"	"1348.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAT6"	"Nuclear protein localization protein 4 homolog OS=Homo sapiens OX=9606 GN=NPLOC4 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"608"	"68.1"	"6.38"	"733.89"	"5.73"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf05020, Pf05021, Pf11543"	"55666"	"ENSG00000182446"	"NPLOC4"	"hsa:55666; Q8N3J1; Q8TAT6; Q9H8V2; Q9H964; Q9NWR5; Q9P229"	""	"Neddylation; KEAP1-NFE2L2 pathway; Translesion Synthesis by POLH"	"3"	"0"	"23.5"	"20.2"	"31.1"	"35.7"	"18.4"	"24.7"	"48.0"	"43.2"	"80.0"	"347.4"	"553.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63220"	"40S ribosomal protein S21 OS=Homo sapiens OX=9606 GN=RPS21 PE=1 SV=1"	"0.000"	""	"23"	"2"	"4"	"2"	"83"	"9.1"	"8.50"	"650.36"	"5.72"	"2"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01249"	"6227"	"ENSG00000171858"	"RPS21"	"hsa:6227; P35265; P63220"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SARS-CoV-2 modulates host translation machinery; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); SARS-CoV-1 modulates host translation machinery"	"19"	"0"	"223.7"	"207.5"	"282.3"	"443.9"	"246.8"	"212.5"	"407.4"	"411.6"	"470.8"	"788.6"	"995.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75940"	"Survival of motor neuron-related-splicing factor 30 OS=Homo sapiens OX=9606 GN=SMNDC1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"238"	"26.7"	"7.24"	"652.56"	"5.71"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf06003"	"10285"	"ENSG00000119953"	"SMNDC1"	"B2RA27; D3DRB1; hsa:10285; O75940; Q5T3K6"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"143.4"	"79.5"	"137.0"	"157.5"	"92.9"	"103.3"	"153.4"	"194.5"	"212.5"	"546.4"	"321.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75122"	"CLIP-associating protein 2 OS=Homo sapiens OX=9606 GN=CLASP2 PE=1 SV=3"	"0.000"	""	"2"	"3"	"4"	"2"	"1294"	"141.0"	"8.40"	"677.51"	"5.71"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf12348"	"23122"	"ENSG00000163539"	"CLASP2"	"B2RTR1; F5H604; hsa:23122; O75122; Q7L8F6; Q8N6R6; Q9BQT3; Q9BQT4; Q9H7A3; Q9NSZ2"	"7q11.23 copy number variation syndrome"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Role of ABL in ROBO-SLIT signaling"	"8"	"1"	"21.6"	"25.5"	"21.5"	"26.0"	"21.0"	"21.2"	"27.2"	"34.1"	"33.1"	"72.7"	"105.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ES7"	"SAGA-associated factor 29 OS=Homo sapiens OX=9606 GN=SGF29 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"293"	"33.2"	"8.10"	"570.90"	"5.70"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07039"	"112869"	"ENSG00000176476"	"SGF29"	"hsa:112869; Q96ES7; Q96MF5"	""	"HATs acetylate histones; Formation of WDR5-containing histone-modifying complexes"	"2"	"0"	"57.1"	"58.9"	"59.0"	"66.7"	"54.0"	"55.4"	"118.5"	"125.5"	"196.8"	"351.8"	"320.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZU8"	"PSME3-interacting protein OS=Homo sapiens OX=9606 GN=PSME3IP1 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"2"	"254"	"28.9"	"5.45"	"592.92"	"5.69"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	""	"Pf10187"	"80011"	"ENSG00000172775"	"PSME3IP1"	"hsa:80011; Q9GZU8"	""	""	"0"	"0"	"90.4"	"84.1"	"99.1"	"117.5"	"84.4"	"83.8"	"134.5"	"150.5"	"194.1"	"477.5"	"698.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95391"	"Pre-mRNA-splicing factor SLU7 OS=Homo sapiens OX=9606 GN=SLU7 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"586"	"68.3"	"7.14"	""	"5.68"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;transport"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11708"	"10569"	"ENSG00000164609"	"SLU7"	"D3DQK2; hsa:10569; O95391; Q3LUJ0; Q3LUJ1; Q6RXQ5; Q96FM9"	""	"mRNA Splicing - Major Pathway; Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"4"	"0"	"16.3"	"20.9"	"11.2"	"18.4"	"16.9"	"16.7"	"25.1"	"31.0"	"35.0"	"88.7"	"103.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15369"	"Elongin-C OS=Homo sapiens OX=9606 GN=ELOC PE=1 SV=1"	"0.000"	""	"18"	"1"	"2"	"1"	"112"	"12.5"	"4.78"	"487.27"	"5.67"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03931"	"6921"	"ENSG00000154582"	"ELOC"	"E5RGD9; hsa:6921; Q15369; Q567Q6"	"Dual hijack model of Vif in HIV infection; VEGFA-VEGFR2 signaling; Type 2 papillary renal cell carcinoma; Hijack of ubiquitination by SARS-CoV-2"	"Regulation of expression of SLITs and ROBOs; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Vif-mediated degradation of APOBEC3G; Neddylation; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; Inactivation of CSF3 (G-CSF) signaling"	"21"	"0"	"10.8"	"10.9"	"20.2"	"19.9"	"14.7"	"14.9"	"28.3"	"28.2"	"37.0"	"78.9"	"106.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27986"	"Phosphatidylinositol 3-kinase regulatory subunit alpha OS=Homo sapiens OX=9606 GN=PIK3R1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"2"	"2"	"724"	"83.5"	"6.16"	"300.13"	"5.67"	"1"	"1"	"cell adhesion;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00620, Pf16454"	"5295"	"ENSG00000145675"	"PIK3R1"	"B3KT19; D3DWA0; E7EX19; hsa:5295; P27986; Q15747; Q4VBZ7; Q53EM6; Q8IXA2; Q8N1C5"	"IL-5 signaling pathway; Androgen receptor signaling pathway; AMP-activated protein kinase signaling; MicroRNAs in cardiomyocyte hypertrophy; IL-1 signaling pathway; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-9 signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Apoptosis; Bladder cancer; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Microglia pathogen phagocytosis pathway; IL-4 signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Overview of interferons-mediated signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Cancer immunotherapy by CTLA4 blockade; Measles virus infection; Small cell lung cancer; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; IL-18 signaling pathway; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; mBDNF and proBDNF regulation of GABA neurotransmission; IL-2 signaling pathway; Modulators of TCR signaling and T cell activation; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; Interferon type I signaling pathways; Notch signaling pathway; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease; RHOJ GTPase cycle; Role of phospholipids in phagocytosis; Role of LAT2/NTAL/LAB on calcium mobilization; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Downstream TCR signaling; RND2 GTPase cycle; RHOG GTPase cycle; G alpha (q) signalling events; RHOD GTPase cycle; RHOF GTPase cycle; Extra-nuclear estrogen signaling; RHOV GTPase cycle; PIP3 activates AKT signaling; Signaling by ALK fusions and activated point mutants; RHOU GTPase cycle; Synthesis of PIPs at the plasma membrane; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RET signaling; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); Interleukin receptor SHC signaling; Regulation of signaling by CBL; Nephrin family interactions; RAF/MAP kinase cascade; PI3K Cascade; GPVI-mediated activation cascade; Interleukin-7 signaling; Signaling by SCF-KIT; Downstream signal transduction; PI3K/AKT activation; Signaling by ALK; Tie2 Signaling; DAP12 signaling; Costimulation by the CD28 family; CD28 dependent PI3K/Akt signaling; VEGFA-VEGFR2 Pathway; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; RND3 GTPase cycle; RND1 GTPase cycle; Interleukin-4 and Interleukin-13 signaling; PI3K events in ERBB4 signaling; PI3K events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; GAB1 signalosome; Signaling by CSF1 (M-CSF) in myeloid cells; PI-3K cascade:FGFR1; PI-3K cascade:FGFR2; Signaling by FGFR2 in disease; PI-3K cascade:FGFR3; PI-3K cascade:FGFR4; Signaling by FGFR3 in disease; FLT3 Signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; Signaling by FLT3 fusion proteins; Signaling by FLT3 ITD and TKD mutants; GP1b-IX-V activation signalling; MET activates PI3K/AKT signaling; Activated NTRK3 signals through PI3K; Activated NTRK2 signals through PI3K"	"150"	"0"	"73.3"	"30.2"	"71.7"	"81.6"	"64.0"	"78.0"	"136.0"	"125.7"	"153.3"	"208.7"	"373.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y277"	"Voltage-dependent anion-selective channel protein 3 OS=Homo sapiens OX=9606 GN=VDAC3 PE=1 SV=1"	"0.001"	""	"8"	"2"	"3"	"1"	"283"	"30.6"	"8.66"	"245.52"	"5.67"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf01459"	"7419"	"ENSG00000078668"	"VDAC3"	"hsa:7419; Q9UIS0; Q9Y277"	"Alzheimer's disease and miRNA effects; Ferroptosis; Hepatitis B infection; Alzheimer's disease"	"Ub-specific processing proteases; Mitochondrial calcium ion transport"	"6"	"0"	"23.0"	"24.3"	"25.1"	"35.1"	"21.2"	"27.6"	"43.0"	"43.4"	"53.8"	"154.0"	"224.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WTT2"	"Nucleolar complex protein 3 homolog OS=Homo sapiens OX=9606 GN=NOC3L PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"800"	"92.5"	"9.17"	"573.38"	"5.65"	"2"	"2"	"DNA metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus"	"other molecular function"	"Pf03914, Pf07540"	"64318"	"ENSG00000173145"	"NOC3L"	"hsa:64318; Q8WTT2; Q9H5M6; Q9H9D8"	""	""	"0"	"0"	"36.8"	"33.8"	"39.8"	"42.4"	"38.5"	"41.5"	"59.6"	"60.0"	"66.3"	"132.4"	"197.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94905"	"Erlin-2 OS=Homo sapiens OX=9606 GN=ERLIN2 PE=1 SV=1"	"0.000"	""	"9"	"4"	"4"	"4"	"339"	"37.8"	"5.62"	"755.68"	"5.65"	"2"	"2"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf01145"	"11160"	"ENSG00000147475"	"ERLIN2"	"A0JLQ1; A8K5S9; B4DM38; D3DSW0; hsa:11160; O94905; Q6NW21; Q86VS6; Q86W49"	""	"ABC-family proteins mediated transport; Defective CFTR causes cystic fibrosis; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions"	"4"	"0"	"26.0"	"31.6"	"27.5"	"39.6"	"27.0"	"26.8"	"63.2"	"63.9"	"98.9"	"245.9"	"347.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPX5"	"Actin-related protein 2/3 complex subunit 5-like protein OS=Homo sapiens OX=9606 GN=ARPC5L PE=1 SV=1"	"0.000"	""	"13"	"2"	"4"	"1"	"153"	"16.9"	"6.60"	"682.40"	"5.63"	"2"	"2"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf04699"	"81873"	"ENSG00000136950"	"ARPC5L"	"hsa:81873; Q7Z523; Q9BPX5"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling"	""	"2"	"0"	"39.8"	"31.1"	"34.0"	"36.5"	"30.0"	"34.2"	"61.9"	"53.8"	"111.5"	"242.5"	"315.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P20290"	"Transcription factor BTF3 OS=Homo sapiens OX=9606 GN=BTF3 PE=1 SV=1"	""	""	"12"	"1"	"1"	"1"	"206"	"22.2"	"9.38"	""	"5.62"	""	"1"	"transport;developmental processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	""	"Pf01849"	"689"	"ENSG00000145741"	"BTF3"	"A8K510; hsa:689; P20290; Q13893; Q76M56"	"Orexin receptor pathway"	""	"1"	"0"	"9.5"	"7.2"	"12.4"	"16.4"	"4.1"	"10.1"	"18.3"	"18.9"	"22.9"	"170.0"	"280.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJX3"	"Anaphase-promoting complex subunit 7 OS=Homo sapiens OX=9606 GN=ANAPC7 PE=1 SV=4"	"0.000"	""	"4"	"2"	"4"	"2"	"599"	"66.8"	"5.64"	"663.78"	"5.62"	"2"	"2"	""	""	""	"Pf13432"	"51434"	""	"ANAPC7"	"A0A024RBJ3; hsa:51434"	""	""	"0"	"0"	"43.3"	"63.3"	"35.9"	"39.3"	"40.1"	"41.3"	"65.1"	"71.3"	"111.0"	"290.2"	"395.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5J9"	"Mitochondrial import inner membrane translocase subunit Tim8 B OS=Homo sapiens OX=9606 GN=TIMM8B PE=1 SV=1"	"0.000"	""	"18"	"2"	"4"	"2"	"83"	"9.3"	"5.12"	"619.97"	"5.62"	"2"	"2"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02953"	"26521"	"ENSG00000150779"	"TIMM8B"	"B0YJA5; hsa:26521; Q3KQS9; Q9UN04; Q9Y5J9"	""	"Mitochondrial protein import"	"1"	"0"	"174.0"	"126.2"	"188.8"	"247.3"	"149.5"	"166.6"	"258.6"	"275.7"	"329.7"	"832.9"	"1388.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75323"	"Protein NipSnap homolog 2 OS=Homo sapiens OX=9606 GN=NIPSNAP2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"1"	"286"	"33.7"	"9.36"	"329.00"	"5.62"	"1"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	""	"Pf07978"	"2631"	"ENSG00000146729"	"NIPSNAP2"	"C9IYJ3; hsa:2631; O43801; O75323; Q53X96"	""	"RHOJ GTPase cycle; RHOH GTPase cycle"	"2"	"0"	"102.2"	"102.2"	"100.9"	"102.6"	"93.6"	"120.9"	"128.7"	"129.1"	"154.9"	"263.1"	"352.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJV9"	"Probable ATP-dependent RNA helicase DDX41 OS=Homo sapiens OX=9606 GN=DDX41 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"622"	"69.8"	"6.84"	"606.68"	"5.61"	"2"	"2"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271"	"51428"	"ENSG00000183258"	"DDX41"	"B2RDC8; hsa:51428; Q96BK6; Q96K05; Q9NT96; Q9NW04; Q9UJV9"	"5q35 copy number variation"	"mRNA Splicing - Major Pathway; Regulation of innate immune responses to cytosolic DNA; IRF3-mediated induction of type I IFN"	"5"	"0"	"25.5"	"17.5"	"27.1"	"32.1"	"19.8"	"14.9"	"31.9"	"35.5"	"46.5"	"122.5"	"215.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29558"	"RNA-binding motif, single-stranded-interacting protein 1 OS=Homo sapiens OX=9606 GN=RBMS1 PE=1 SV=3"	"0.000"	""	"4"	"2"	"5"	"2"	"406"	"44.5"	"8.79"	"926.00"	"5.61"	"2"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"5937"	"ENSG00000153250"	"RBMS1"	"hsa:5937; P29558; Q14869; Q15433; Q53P46; Q53QX8; Q53RG6; Q8WV20"	""	""	"0"	"0"	"174.9"	"173.0"	"189.6"	"193.0"	"150.1"	"138.8"	"208.4"	"200.5"	"217.9"	"311.4"	"391.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TAE8"	"Growth arrest and DNA damage-inducible proteins-interacting protein 1 OS=Homo sapiens OX=9606 GN=GADD45GIP1 PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"222"	"25.4"	"10.02"	"738.36"	"5.61"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	""	"Pf10147"	"90480"	"ENSG00000179271"	"GADD45GIP1"	"hsa:90480; Q8IVM3; Q8TAE8; Q8TE51; Q969P9; Q9BSM6"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"78.4"	"67.0"	"90.6"	"99.0"	"79.9"	"86.1"	"138.1"	"135.2"	"165.0"	"240.9"	"365.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ13"	"Leucine-rich repeat protein SHOC-2 OS=Homo sapiens OX=9606 GN=SHOC2 PE=1 SV=2"	"0.001"	""	"6"	"2"	"2"	"2"	"582"	"64.8"	"8.46"	"234.51"	"5.61"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf13855"	"8036"	"ENSG00000108061"	"SHOC2"	"A8K9W8; B3KR23; hsa:8036; O76063; Q5VZS8; Q5VZS9; Q9UQ13"	"Ras signaling; 22q11.2 copy number variation syndrome; Autophagy in pancreatic ductal adenocarcinoma"	"RAF activation; SHOC2 M1731 mutant abolishes MRAS complex function; Gain-of-function MRAS complexes activate RAF signaling"	"6"	"0"	"34.5"	"21.5"	"47.2"	"55.1"	"32.3"	"36.9"	"58.4"	"72.4"	"118.9"	"309.0"	"290.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIA9"	"Exportin-7 OS=Homo sapiens OX=9606 GN=XPO7 PE=1 SV=3"	"0.000"	""	"2"	"1"	"4"	"1"	"1087"	"123.8"	"6.32"	"708.14"	"5.60"	"1"	"1"	"transport"	"nucleus;other cell component"	"other molecular function"	"Pf03810"	"23039"	"ENSG00000130227"	"XPO7"	"hsa:23039; O94846; Q6PJK9; Q8NEK7; Q9UIA9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P58546"	"Myotrophin OS=Homo sapiens OX=9606 GN=MTPN PE=1 SV=2"	"0.000"	""	"6"	"1"	"4"	"1"	"118"	"12.9"	"5.52"	"558.00"	"5.59"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf12796"	"136319"	"ENSG00000105887"	"MTPN"	"hsa:136319; P58546"	""	""	"0"	"0"	"117.4"	"141.6"	"164.0"	"271.3"	"107.3"	"90.9"	"170.6"	"192.4"	"211.3"	"400.1"	"481.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P28070"	"Proteasome subunit beta type-4 OS=Homo sapiens OX=9606 GN=PSMB4 PE=1 SV=4"	""	""	"9"	"1"	"1"	"1"	"264"	"29.2"	"5.97"	""	"5.59"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5692"	"ENSG00000159377"	"PSMB4"	"B2R9L3; hsa:5692; P28070; P31148; Q5SZS5; Q6IBI4; Q969L6"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of expression of SLITs and ROBOs; Regulation of PTEN stability and activity; KEAP1-NFE2L2 pathway; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Neddylation; Interleukin-1 signaling; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"11.3"	"14.8"	"4.5"	"11.1"	"9.0"	"10.3"	"13.1"	"13.3"	"13.1"	"34.4"	"80.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QE3"	"ATPase family AAA domain-containing protein 5 OS=Homo sapiens OX=9606 GN=ATAD5 PE=1 SV=4"	"0.000"	""	"1"	"2"	"3"	"2"	"1844"	"207.4"	"9.19"	"310.09"	"5.59"	"1"	"2"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00004"	"79915"	"ENSG00000176208"	"ATAD5"	"hsa:79915; Q05DH0; Q69YR6; Q96QE3; Q9H9I1"	""	""	"0"	"0"	"13.1"	"9.5"	"14.3"	"18.0"	"13.3"	"12.2"	"26.9"	"24.6"	"34.3"	"52.2"	"65.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51398"	"28S ribosomal protein S29, mitochondrial OS=Homo sapiens OX=9606 GN=DAP3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"398"	"45.5"	"8.88"	"462.95"	"5.59"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10236"	"7818"	"ENSG00000132676"	"DAP3"	"B4DP59; B4DY62; E7EM60; hsa:7818; P51398; Q13044; Q68CT7; Q96Q20"	"CKAP4 signaling pathway map"	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"4"	"0"	"36.0"	"32.0"	"60.1"	"49.9"	"46.0"	"39.8"	"64.1"	"71.5"	"72.3"	"144.7"	"213.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U06"	"Probable RNA-binding protein 23 OS=Homo sapiens OX=9606 GN=RBM23 PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"1"	"439"	"48.7"	"9.85"	"533.60"	"5.58"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf15519"	"55147"	"ENSG00000100461"	"RBM23"	"D3DS32; hsa:55147; Q86U06; Q8ND16; Q8TB88; Q8WY40; Q9BUJ1; Q9NVV7"	""	""	"0"	"0"	"10.5"	"9.7"	"9.9"	"15.7"	"7.2"	"11.2"	"21.6"	"11.8"	"24.9"	"48.5"	"50.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQN3"	"Charged multivesicular body protein 2b OS=Homo sapiens OX=9606 GN=CHMP2B PE=1 SV=1"	"0.000"	""	"9"	"2"	"4"	"2"	"213"	"23.9"	"8.76"	"724.92"	"5.57"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"25978"	"ENSG00000083937"	"CHMP2B"	"B4DJG8; hsa:25978; Q53HC7; Q9UQN3; Q9Y4U6"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III; Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"167.3"	"153.8"	"198.2"	"216.9"	"154.1"	"168.4"	"229.2"	"218.9"	"247.1"	"675.5"	"765.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRJ7"	"Tudor-interacting repair regulator protein OS=Homo sapiens OX=9606 GN=NUDT16L1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"4"	"1"	"211"	"23.3"	"8.91"	"741.73"	"5.57"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	""	"84309"	"ENSG00000168101"	"NUDT16L1"	"hsa:84309; Q8NAI2; Q9BRJ7"	""	""	"0"	"0"	"4.6"	"7.8"	"4.7"	"10.9"	"4.2"	"4.6"	"10.4"	"9.7"	"12.0"	"33.5"	"50.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ83"	"2-hydroxyacyl-CoA lyase 1 OS=Homo sapiens OX=9606 GN=HACL1 PE=1 SV=2"	"0.000"	""	"5"	"2"	"4"	"2"	"578"	"63.7"	"7.36"	"671.47"	"5.56"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;transport"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"26061"	"ENSG00000131373"	"HACL1"	"B4DWI1; B4DXI5; E9PEN4; hsa:26061; Q9BV42; Q9P0A2; Q9UJ83"	""	"Peroxisomal protein import; Alpha-oxidation of phytanate"	"2"	"0"	"18.9"	"16.4"	"22.8"	"20.2"	"21.0"	"22.9"	"37.2"	"38.5"	"76.1"	"154.1"	"165.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVP1"	"ATP-dependent RNA helicase DDX18 OS=Homo sapiens OX=9606 GN=DDX18 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"670"	"75.4"	"9.50"	"505.12"	"5.56"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"8886"	"ENSG00000088205"	"DDX18"	"hsa:8886; Q6GTZ9; Q6IAU4; Q92732; Q9BQB7; Q9NVP1"	""	""	"0"	"0"	"0.0"	"0.0"	"2.6"	"7.5"	"2.8"	"0.0"	"5.5"	"8.9"	"11.4"	"57.9"	"81.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VZE5"	"N-alpha-acetyltransferase 35, NatC auxiliary subunit OS=Homo sapiens OX=9606 GN=NAA35 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"725"	"83.6"	"7.05"	"520.88"	"5.55"	"2"	"2"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf04112"	"60560"	"ENSG00000135040"	"NAA35"	"hsa:60560; Q5VZE5; Q5VZE6; Q9H631; Q9H703"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"6.2"	"7.4"	"9.5"	"13.9"	"4.9"	"11.0"	"25.2"	"26.6"	"63.3"	"147.7"	"186.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2W1"	"Homologous-pairing protein 2 homolog OS=Homo sapiens OX=9606 GN=PSMC3IP PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"217"	"24.9"	"7.81"	"902.85"	"5.55"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07106, Pf18517"	"29893"	"ENSG00000131470"	"PSMC3IP"	"C5ILB7; hsa:29893; Q14458; Q8WXG2; Q96HA2; Q9P2W1"	"Androgen receptor signaling pathway; Primary ovarian insufficiency"	"Meiotic recombination"	"3"	"0"	"31.4"	"31.2"	"44.8"	"54.9"	"41.0"	"30.1"	"71.7"	"61.8"	"102.1"	"197.9"	"190.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4W2"	"Ribosomal biogenesis protein LAS1L OS=Homo sapiens OX=9606 GN=LAS1L PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"734"	"83.0"	"4.73"	"763.35"	"5.55"	"2"	"2"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04031"	"81887"	"ENSG00000001497"	"LAS1L"	"A9X410; hsa:81887; Q5JXQ0; Q8TEN5; Q9H9V5; Q9Y4W2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"134.4"	"97.0"	"148.6"	"171.8"	"138.9"	"122.6"	"181.2"	"188.3"	"212.9"	"404.3"	"605.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75175"	"CCR4-NOT transcription complex subunit 3 OS=Homo sapiens OX=9606 GN=CNOT3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"753"	"81.8"	"6.20"	"599.69"	"5.52"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf04065, Pf04153"	"4849"	"ENSG00000088038; ENSG00000273943; ENSG00000274176; ENSG00000274616; ENSG00000274941; ENSG00000275979; ENSG00000276082; ENSG00000277114; ENSG00000277600; ENSG00000277615"	"CNOT3"	"hsa:4849; O75175; Q9NZN7; Q9UF76"	""	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"2"	"0"	"31.3"	"22.0"	"36.9"	"50.9"	"35.6"	"23.0"	"68.4"	"63.8"	"93.1"	"371.6"	"908.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP61"	"ADP-ribosylation factor GTPase-activating protein 3 OS=Homo sapiens OX=9606 GN=ARFGAP3 PE=1 SV=1"	"0.000"	""	"4"	"2"	"4"	"2"	"516"	"56.9"	"7.36"	"761.50"	"5.51"	"2"	"2"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf01412"	"26286"	"ENSG00000242247"	"ARFGAP3"	"E9PB03; hsa:26286; Q9BSC6; Q9H9J0; Q9NP61; Q9NT10; Q9NUP5; Q9Y4V3; Q9Y4V4"	"Ciliary landscape"	"COPI-mediated anterograde transport; CDC42 GTPase cycle; RHOG GTPase cycle; COPI-dependent Golgi-to-ER retrograde traffic"	"5"	"0"	"146.4"	"134.0"	"181.3"	"195.2"	"152.8"	"168.7"	"280.5"	"297.1"	"439.8"	"909.6"	"1029.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWF6"	"Protein DENND6A OS=Homo sapiens OX=9606 GN=DENND6A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"608"	"69.5"	"8.27"	"589.83"	"5.51"	"1"	"1"	"other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf08616, Pf09794"	"201627"	"ENSG00000174839"	"DENND6A"	"hsa:201627; Q7Z5T4; Q8IWF6; Q8N235; Q8TEG8"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"35.4"	"36.8"	"30.9"	"33.4"	"28.0"	"33.9"	"49.7"	"45.5"	"54.4"	"65.9"	"56.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75874"	"Isocitrate dehydrogenase [NADP] cytoplasmic OS=Homo sapiens OX=9606 GN=IDH1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"414"	"46.6"	"7.01"	"589.24"	"5.49"	"2"	"2"	"other metabolic processes;stress response;developmental processes;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00180"	"3417"	"ENSG00000138413"	"IDH1"	"hsa:3417; O75874; Q567U4; Q6FHQ6; Q7Z3V0; Q93090; Q9NTJ9; Q9UKW8"	"Glutathione metabolism; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism"	"Peroxisomal protein import; Neutrophil degranulation; Abnormal conversion of 2-oxoglutarate to 2-hydroxyglutarate; NADPH regeneration; NFE2L2 regulating TCA cycle genes"	"8"	"0"	"105.1"	"99.5"	"141.5"	"153.0"	"103.2"	"99.0"	"154.0"	"144.5"	"187.3"	"539.5"	"1061.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T440"	"Putative transferase CAF17, mitochondrial OS=Homo sapiens OX=9606 GN=IBA57 PE=1 SV=1"	"0.001"	""	"8"	"2"	"3"	"2"	"356"	"38.1"	"9.83"	"252.64"	"5.49"	"1"	"2"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion"	"other molecular function"	""	"200205"	"ENSG00000181873"	"IBA57"	"hsa:200205; Q5T440"	""	""	"0"	"0"	"134.8"	"92.0"	"151.4"	"183.1"	"117.5"	"113.6"	"199.1"	"212.7"	"274.2"	"558.8"	"674.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N6R0"	"eEF1A lysine and N-terminal methyltransferase OS=Homo sapiens OX=9606 GN=EEF1AKNMT PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"699"	"78.7"	"6.73"	"396.01"	"5.49"	"1"	"2"	"other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01564, Pf08241"	"51603"	"ENSG00000010165"	"METTL13"	"A6NFK0; A8K6S5; hsa:51603; O94940; Q53EZ6; Q5TGP9; Q5TGQ0; Q8N2P8; Q8N6R0; Q96J11; Q96SQ0; Q9Y2Z1; Q9Y3M6"	""	""	"0"	"0"	"9.5"	"8.3"	"10.4"	"13.4"	"13.6"	"9.0"	"25.3"	"26.7"	"48.6"	"147.4"	"234.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15530"	"3-phosphoinositide-dependent protein kinase 1 OS=Homo sapiens OX=9606 GN=PDPK1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"556"	"63.1"	"7.36"	"629.17"	"5.48"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf14593"	"5170"	"ENSG00000140992"	"PDPK1"	"H0Y4Z0; hsa:5170; O15530; Q59EH6; Q6FI20; Q8IV52; Q9BRD5"	"MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac hypertrophic response; Focal adhesion; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin-insulin signaling overlap; PPAR signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; EGF/EGFR signaling pathway; Head and neck squamous cell carcinoma; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Modulators of TCR signaling and T cell activation; GDNF signaling; Primary ovarian insufficiency; A network map of Macrophage-stimulating protein (MSP) signaling; ErbB signaling pathway; T-cell receptor signaling pathway; Serotonin HTR1 group and FOS pathway"	"Role of LAT2/NTAL/LAB on calcium mobilization; FCERI mediated NF-kB activation; Downstream TCR signaling; CLEC7A (Dectin-1) signaling; Constitutive Signaling by AKT1 E17K in Cancer; PIP3 activates AKT signaling; Regulation of TP53 Degradation; GPVI-mediated activation cascade; CD28 dependent PI3K/Akt signaling; G beta:gamma signalling through PI3Kgamma; RHO GTPases activate PKNs; Activation of AKT2; Integrin signaling; RSK activation; VEGFR2 mediated vascular permeability; VEGFR2 mediated cell proliferation; Estrogen-stimulated signaling through PRKCZ; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; SARS-CoV-2 targets host intracellular signalling and regulatory pathways"	"46"	"0"	"11.2"	"6.9"	"11.7"	"20.1"	"19.2"	"24.7"	"75.3"	"81.3"	"106.4"	"184.9"	"223.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0V9"	"Septin-10 OS=Homo sapiens OX=9606 GN=SEPTIN10 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"454"	"52.6"	"6.80"	"621.69"	"5.48"	"2"	"2"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"151011"	"ENSG00000186522"	"SEPTIN10"	"B3KRQ9; hsa:151011; Q86VP5; Q9HAH6; Q9P0V9"	""	""	"0"	"0"	"54.1"	"41.4"	"51.8"	"64.4"	"45.7"	"46.8"	"109.5"	"121.5"	"196.8"	"450.9"	"588.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50750"	"Cyclin-dependent kinase 9 OS=Homo sapiens OX=9606 GN=CDK9 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"1"	"372"	"42.8"	"8.79"	"350.19"	"5.47"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"1025"	"ENSG00000136807"	"CDK9"	"hsa:1025; P50750; Q5JU24; Q5JU25; Q5U006; Q96TF1"	"MicroRNAs in cardiomyocyte hypertrophy; IL-9 signaling pathway; Cardiac hypertrophic response; Initiation of transcription and translation elongation at the HIV-1 LTR; Male infertility"	"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Estrogen-dependent gene expression; Interactions of Tat with host cellular proteins"	"20"	"0"	"74.3"	"62.3"	"80.7"	"73.9"	"74.2"	"71.0"	"117.8"	"115.8"	"153.9"	"237.0"	"311.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L73"	"Histone-lysine N-methyltransferase, H3 lysine-36 specific OS=Homo sapiens OX=9606 GN=NSD1 PE=1 SV=1"	"0.000"	""	"1"	"2"	"4"	"2"	"2696"	"296.5"	"8.03"	"724.62"	"5.47"	"2"	"2"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00855, Pf00856, Pf17907, Pf17982"	"64324"	"ENSG00000165671"	"NSD1"	"hsa:64324; Q96L73; Q96PD8; Q96RN7"	"Histone modifications; Pathways affected in adenoid cystic carcinoma; 5q35 copy number variation"	"PKMTs methylate histone lysines"	"4"	"0"	"54.0"	"48.9"	"63.0"	"81.1"	"53.0"	"50.8"	"86.2"	"91.4"	"132.4"	"242.4"	"327.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A1L170"	"Uncharacterized protein C1orf226 OS=Homo sapiens OX=9606 GN=C1orf226 PE=1 SV=1"	""	""	"8"	"1"	"1"	"1"	"272"	"29.0"	"5.27"	""	"5.47"	""	"1"	""	""	""	"Pf15429"	"400793"	"ENSG00000239887"	"C1orf226"	"A1L170; B4DF31; hsa:400793"	""	""	"0"	"0"	"30.5"	"15.0"	"29.4"	"36.0"	"27.7"	"30.2"	"37.4"	"30.9"	"57.5"	"82.3"	"123.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZZ9"	"Ubiquitin-like modifier-activating enzyme 5 OS=Homo sapiens OX=9606 GN=UBA5 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"404"	"44.8"	"4.84"	"356.81"	"5.46"	"1"	"2"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00899"	"79876"	"ENSG00000081307"	"UBA5"	"A6NJL3; D3DNC8; hsa:79876; Q96ST1; Q9GZZ9"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"124.8"	"90.3"	"109.8"	"141.0"	"125.5"	"130.8"	"151.9"	"158.0"	"186.5"	"292.8"	"378.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43663"	"Protein regulator of cytokinesis 1 OS=Homo sapiens OX=9606 GN=PRC1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"6"	"2"	"620"	"71.6"	"6.68"	"1700.38"	"5.45"	"3"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03999"	"9055"	"ENSG00000198901"	"PRC1"	"A6NC44; B4DLR1; H9KV59; hsa:9055; O43663; Q9BSB6"	""	"RHO GTPases activate CIT"	"1"	"0"	"108.1"	"133.5"	"100.9"	"144.3"	"110.0"	"115.6"	"200.6"	"222.6"	"282.5"	"441.8"	"523.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06787"	"Synaptic functional regulator FMR1 OS=Homo sapiens OX=9606 GN=FMR1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"1"	"632"	"71.1"	"7.42"	"537.09"	"5.45"	"2"	"2"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"cytoskeletal activity;translation activity;nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16098, Pf17904, Pf18336"	"2332"	"ENSG00000102081"	"FMR1"	"A6NNH4; D3DWT0; D3DWT1; D3DWT2; G8JL90; hsa:2332; Q06787; Q16578; Q5PQZ6; Q99054"	"Ovarian infertility; Serotonin and anxiety; Prader-Willi and Angelman syndrome; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; 15q11.2 copy number variation syndrome; Primary ovarian insufficiency"	""	"7"	"1"	"210.7"	"198.1"	"231.3"	"292.3"	"204.9"	"197.3"	"297.6"	"300.1"	"334.5"	"573.8"	"757.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13017"	"Rho GTPase-activating protein 5 OS=Homo sapiens OX=9606 GN=ARHGAP5 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1502"	"172.4"	"6.62"	"443.75"	"5.44"	"1"	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"394"	"ENSG00000100852"	"ARHGAP5"	"A1L375; A1L376; A8KAA1; D3DS89; D3DS90; hsa:394; Q05BE8; Q05BU8; Q13017; Q59ER0; Q6DHZ3"	"Focal adhesion"	"RHOC GTPase cycle; RND2 GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RHOF GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle"	"15"	"0"	"14.3"	"15.7"	"20.8"	"26.8"	"11.3"	"18.5"	"50.7"	"59.9"	"99.7"	"275.0"	"374.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPX6"	"Calcium uptake protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=MICU1 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"476"	"54.3"	"8.41"	"759.87"	"5.44"	"2"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf13202"	"10367"	"ENSG00000107745"	"MICU1"	"A8MV96; B3KN20; B4DJH9; B4DPI1; B5MBY3; D3YTJ3; hsa:10367; O75785; Q9BPX6; Q9H9N6; Q9UFX0"	""	"Processing of SMDT1"	"2"	"0"	"58.3"	"74.3"	"62.7"	"74.2"	"57.1"	"68.2"	"126.1"	"130.4"	"230.4"	"346.4"	"406.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P1Y6"	"PHD and RING finger domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PHRF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1649"	"178.6"	"8.95"	"596.67"	"5.43"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf00628, Pf13639"	"57661"	"ENSG00000070047; ENSG00000274780"	"PHRF1"	"A6H8W1; B7ZM64; B9EGP0; C9JS82; hsa:57661; Q6PJP2; Q8IVY2; Q8N2Y7; Q9BSM2; Q9P1Y6"	""	""	"0"	"0"	"46.4"	"44.1"	"47.2"	"56.7"	"47.1"	"42.2"	"68.5"	"75.6"	"72.4"	"154.4"	"185.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94874"	"E3 UFM1-protein ligase 1 OS=Homo sapiens OX=9606 GN=UFL1 PE=1 SV=2"	"0.000"	""	"5"	"3"	"5"	"3"	"794"	"89.5"	"6.79"	"792.11"	"5.43"	"3"	"2"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf09743"	"23376"	"ENSG00000014123"	"UFL1"	"A0PJ53; B4DJ57; C0H5X5; hsa:23376; O94874; Q8N765; Q9NTQ0"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"12.1"	"5.3"	"7.0"	"13.3"	"8.6"	"8.3"	"14.5"	"24.4"	"41.0"	"114.3"	"152.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BU23"	"Lipase maturation factor 2 OS=Homo sapiens OX=9606 GN=LMF2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"707"	"79.6"	"10.10"	""	"5.42"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf06762"	"91289"	"ENSG00000100258"	"LMF2"	"A6NEZ0; hsa:91289; Q13392; Q6ZNR2; Q8WU74; Q96C62; Q9BU23"	""	"Assembly of active LPL and LIPC lipase complexes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5T1V6"	"Probable ATP-dependent RNA helicase DDX59 OS=Homo sapiens OX=9606 GN=DDX59 PE=1 SV=1"	""	""	"4"	"2"	"2"	"2"	"619"	"68.8"	"7.44"	""	"5.42"	""	"2"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04438"	"83479"	"ENSG00000118197"	"DDX59"	"hsa:83479; Q5T1V6; Q6PJL2; Q8IVW3; Q9H0W3"	"Ciliopathies"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86US8"	"Telomerase-binding protein EST1A OS=Homo sapiens OX=9606 GN=SMG6 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1419"	"160.4"	"7.05"	"579.43"	"5.41"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10373, Pf10374, Pf13638"	"23293"	"ENSG00000070366"	"SMG6"	"B7Z874; hsa:23293; O94837; Q86US8; Q86VH6; Q9UF60"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	"50.6"	"67.6"	"78.5"	"64.1"	"60.8"	"53.5"	"86.8"	"90.7"	"116.9"	"235.0"	"304.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50914"	"60S ribosomal protein L14 OS=Homo sapiens OX=9606 GN=RPL14 PE=1 SV=4"	"0.000"	""	"8"	"2"	"3"	"2"	"215"	"23.4"	"10.93"	"356.30"	"5.40"	"1"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01929"	"9045"	"ENSG00000188846"	"RPL14"	"hsa:9045; P50914; Q45RF0; Q53G20; Q8TBD5; Q8WUT0; Q92579; Q96GR0; Q9BSB8; Q9BW65; Q9BYF6"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"188.9"	"183.8"	"276.8"	"333.1"	"284.2"	"173.2"	"368.5"	"376.0"	"486.7"	"1048.8"	"1720.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NDT2"	"Putative RNA-binding protein 15B OS=Homo sapiens OX=9606 GN=RBM15B PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"1"	"890"	"97.1"	"9.85"	"533.03"	"5.40"	"2"	"2"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf07744"	"29890"	"ENSG00000259956"	"RBM15B"	"A4QPG7; hsa:29890; Q6QE19; Q8NDT2; Q9BV96"	""	""	"0"	"0"	"33.2"	"50.2"	"40.2"	"60.4"	"45.8"	"46.0"	"70.1"	"83.2"	"108.7"	"241.2"	"316.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPU7"	"TBC1 domain family member 2B OS=Homo sapiens OX=9606 GN=TBC1D2B PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"963"	"109.8"	"6.16"	"312.00"	"5.39"	"1"	"2"	"transport;other biological processes"	"cytosol;other cytoplasmic organelle"	"enzyme regulator activity"	"Pf00169, Pf00566"	"23102"	"ENSG00000167202"	"TBC1D2B"	"A7MD42; hsa:23102; Q8N1F9; Q9NXM0; Q9UPU7"	""	""	"0"	"0"	"10.7"	"10.2"	"11.3"	"9.0"	"7.8"	"7.8"	"11.6"	"12.7"	"11.9"	"22.4"	"31.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33316"	"Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial OS=Homo sapiens OX=9606 GN=DUT PE=1 SV=4"	"0.000"	""	"13"	"3"	"5"	"3"	"252"	"26.5"	"9.36"	"1005.54"	"5.39"	"3"	"2"	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"signal transduction activity or receptor binding;other molecular function"	"Pf00692"	"1854"	"ENSG00000128951"	"DUT"	"A8K650; B4DPR5; hsa:1854; O14785; P33316; Q16708; Q16860; Q6FHN1; Q6NSA3; Q96Q81"	"Pyrimidine metabolism"	""	"1"	"0"	"137.6"	"112.6"	"153.9"	"206.5"	"118.5"	"121.4"	"206.4"	"187.8"	"237.7"	"565.0"	"906.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19174"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 OS=Homo sapiens OX=9606 GN=PLCG1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"1290"	"148.4"	"6.05"	"601.25"	"5.38"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00387, Pf00388"	"5335"	"ENSG00000124181"	"PLCG1"	"B7ZLY7; B9EGH4; E1P5W4; hsa:5335; P19174; Q2V575"	"Angiogenesis; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; PDGF pathway; Primary focal segmental glomerulosclerosis (FSGS); T cell receptor and co-stimulatory signaling; Myometrial relaxation and contraction pathways; Kit receptor signaling pathway; MFAP5-mediated ovarian cancer cell motility and invasiveness; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; GPR40 pathway; Ras signaling; Non-small cell lung cancer; EGF/EGFR signaling pathway; Resistin as a regulator of inflammation; Fragile X syndrome; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; mBDNF and proBDNF regulation of GABA neurotransmission; Modulators of TCR signaling and T cell activation; CCL18 signaling pathway; Th17 cell differentiation pathway; GDNF signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; ErbB signaling pathway; T-cell receptor signaling pathway"	"ISG15 antiviral mechanism; Role of phospholipids in phagocytosis; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Generation of second messenger molecules; Signaling by ALK fusions and activated point mutants; RET signaling; Downstream signal transduction; Signaling by ALK; DAP12 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; EGFR interacts with phospholipase C-gamma; Signaling by FGFR1 in disease; Synthesis of IP3 and IP4 in the cytosol; Phospholipase C-mediated cascade: FGFR1; Phospholipase C-mediated cascade; FGFR2; Signaling by FGFR2 in disease; VEGFR2 mediated cell proliferation; Phospholipase C-mediated cascade; FGFR3; Phospholipase C-mediated cascade; FGFR4; Signaling by FGFR3 in disease; DAG and IP3 signaling; Erythropoietin activates Phospholipase C gamma (PLCG); Role of second messengers in netrin-1 signaling; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; PLCG1 events in ERBB2 signaling; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Signaling by FGFR4 in disease; PLC-gamma1 signalling; PECAM1 interactions; Activated NTRK2 signals through PLCG1; Activated NTRK3 signals through PLCG1"	"73"	"0"	"19.6"	"17.2"	"23.2"	"27.9"	"20.7"	"18.7"	"33.5"	"37.1"	"55.2"	"216.1"	"427.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZMI0"	"Protein phosphatase 1 regulatory subunit 21 OS=Homo sapiens OX=9606 GN=PPP1R21 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"780"	"88.3"	"6.84"	"610.09"	"5.37"	"1"	"1"	""	"other cytoplasmic organelle"	""	"Pf10205, Pf10212"	"129285"	"ENSG00000162869"	"PPP1R21"	"B7ZKY5; B7ZKY7; E1B6W7; hsa:129285; Q2TA78; Q6ZMI0; Q6ZMI6; Q8IW83; Q8J029; Q96ES8"	""	""	"0"	"0"	"32.6"	"26.1"	"41.2"	"37.8"	"23.9"	"23.1"	"52.7"	"69.2"	"83.1"	"235.4"	"324.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14578"	"Citron Rho-interacting kinase OS=Homo sapiens OX=9606 GN=CIT PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"2027"	"231.3"	"6.57"	"331.16"	"5.36"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00169, Pf00780"	"11113"	"ENSG00000122966"	"CIT"	"hsa:11113; O14578; Q2M5E1; Q6XUH8; Q86UQ9; Q9UPZ7"	"Pleural mesothelioma; G13 signaling pathway"	"RHOC GTPase cycle; RHOA GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RHO GTPases activate CIT"	"7"	"0"	"10.1"	"10.5"	"10.9"	"12.7"	"10.7"	"6.0"	"16.7"	"17.3"	"24.3"	"57.6"	"70.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H857"	"5'-nucleotidase domain-containing protein 2 OS=Homo sapiens OX=9606 GN=NT5DC2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"520"	"60.7"	"6.77"	"581.98"	"5.35"	"1"	"1"	""	""	"other molecular function"	"Pf05761"	"64943"	"ENSG00000168268"	"NT5DC2"	"C9JTZ6; E9PAL9; hsa:64943; O95888; Q96C80; Q9H857; Q9H9Z8"	""	""	"0"	"0"	"41.3"	"39.4"	"45.1"	"54.6"	"39.5"	"63.0"	"84.0"	"82.4"	"119.9"	"267.1"	"300.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWC1"	"MAP7 domain-containing protein 3 OS=Homo sapiens OX=9606 GN=MAP7D3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"876"	"98.4"	"9.32"	"719.89"	"5.35"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf05672"	"79649"	"ENSG00000129680"	"MAP7D3"	"A2A2J0; A6NCZ7; A6NHR4; B4DWD2; H7BY77; hsa:79649; Q5JXI5; Q5JXI6; Q6P2S1; Q8IWC1; Q9H9M8"	""	""	"0"	"0"	"130.1"	"109.2"	"130.1"	"158.8"	"120.9"	"123.1"	"156.2"	"152.8"	"195.7"	"228.7"	"253.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43929"	"Origin recognition complex subunit 4 OS=Homo sapiens OX=9606 GN=ORC4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"436"	"50.3"	"8.00"	"478.29"	"5.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13191, Pf14629"	"5000"	"ENSG00000115947"	"ORC4"	"B7Z3D0; B7Z5F1; D3DP86; F5H069; hsa:5000; O43929; Q96C42"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"10"	"0"	"43.7"	"48.5"	"55.5"	"59.9"	"50.0"	"42.8"	"70.8"	"76.0"	"92.8"	"169.6"	"215.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2U8"	"Inner nuclear membrane protein Man1 OS=Homo sapiens OX=9606 GN=LEMD3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"911"	"99.9"	"7.55"	"630.02"	"5.34"	"1"	"1"	"other biological processes"	"other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03020, Pf09402"	"23592"	"ENSG00000174106"	"LEMD3"	"hsa:23592; Q9NT47; Q9NYA5; Q9Y2U8"	"Envelope proteins and their potential roles in EDMD physiopathology"	"RND2 GTPase cycle; RAC1 GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RND3 GTPase cycle; RND1 GTPase cycle; Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina"	"12"	"0"	"70.0"	"97.7"	"53.7"	"83.0"	"54.0"	"61.4"	"161.4"	"172.2"	"262.6"	"644.2"	"682.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3B726"	"DNA-directed RNA polymerase I subunit RPA43 OS=Homo sapiens OX=9606 GN=TWISTNB PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"338"	"37.4"	"6.98"	"579.95"	"5.33"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	"Pf17875"	"221830"	"ENSG00000105849"	"POLR1F"	"A0PJ45; B7Z724; hsa:221830; Q3B726"	"Pyrimidine metabolism; 2q13 copy number variation syndrome"	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"7"	"0"	"6.7"	"7.5"	"1.7"	"6.2"	"3.8"	"3.7"	"16.6"	"19.8"	"39.9"	"73.4"	"71.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49458"	"Signal recognition particle 9 kDa protein OS=Homo sapiens OX=9606 GN=SRP9 PE=1 SV=2"	"0.000"	""	"22"	"2"	"4"	"2"	"86"	"10.1"	"7.97"	"576.96"	"5.32"	"2"	"2"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf05486"	"6726"	"ENSG00000143742"	"SRP9"	"A8K0N0; hsa:6726; P49458; Q6NVX0; Q8WTW0"	""	"SRP-dependent cotranslational protein targeting to membrane"	"1"	"0"	"87.9"	"111.5"	"96.8"	"149.2"	"98.7"	"78.5"	"192.5"	"213.9"	"310.8"	"388.2"	"559.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52747"	"Zinc finger protein 143 OS=Homo sapiens OX=9606 GN=ZNF143 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"638"	"68.9"	"6.05"	"394.79"	"5.31"	"1"	"2"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7702"	"ENSG00000166478"	"ZNF143"	"A8K518; B4DLY5; E7ER34; hsa:7702; O75559; P52747; Q8WUK9"	"IL-18 signaling pathway"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA polymerase II transcribes snRNA genes"	"4"	"0"	"208.4"	"282.2"	"222.6"	"275.1"	"234.8"	"199.4"	"330.3"	"350.5"	"408.0"	"760.2"	"916.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11274"	"Breakpoint cluster region protein OS=Homo sapiens OX=9606 GN=BCR PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"1271"	"142.7"	"7.03"	"304.05"	"5.30"	"1"	"2"	"cell adhesion;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00168, Pf00620, Pf00621, Pf09036, Pf19057"	"613"	"ENSG00000186716"	"BCR"	"hsa:613; P11274; P78501; Q12842; Q4LE80; Q6NZI3"	"Imatinib and chronic myeloid leukemia; Extrafollicular and follicular B cell activation by SARS-CoV-2"	"RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; Signaling by cytosolic FGFR1 fusion mutants; Signaling by FGFR1 in disease"	"11"	"0"	"30.0"	"29.5"	"39.0"	"55.5"	"32.1"	"32.1"	"93.9"	"125.3"	"211.8"	"510.8"	"574.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95793"	"Double-stranded RNA-binding protein Staufen homolog 1 OS=Homo sapiens OX=9606 GN=STAU1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"577"	"63.1"	"9.44"	"478.86"	"5.30"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00035, Pf16482"	"6780"	"ENSG00000124214"	"STAU1"	"A8K9Z4; E1P5Y1; E1P608; hsa:6780; O95793; Q5JW29; Q6GTM4; Q9H5B4; Q9H5B5; Q9Y3Q2"	""	""	"0"	"0"	"36.3"	"30.9"	"50.5"	"59.4"	"40.6"	"42.1"	"66.8"	"50.3"	"59.8"	"113.1"	"165.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13884"	"Beta-1-syntrophin OS=Homo sapiens OX=9606 GN=SNTB1 PE=1 SV=3"	"0.000"	""	"6"	"3"	"5"	"3"	"538"	"58.0"	"8.63"	"924.40"	"5.30"	"3"	"2"	"other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169, Pf00595, Pf18012"	"6641"	"ENSG00000172164"	"SNTB1"	"A8K9E0; hsa:6641; O14912; Q13884; Q4KMG8"	"IL-18 signaling pathway; 13q12.12 copy number variation"	""	"2"	"0"	"76.1"	"57.5"	"88.9"	"106.4"	"65.9"	"61.4"	"126.1"	"143.6"	"189.9"	"458.7"	"614.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UFW8"	"CGG triplet repeat-binding protein 1 OS=Homo sapiens OX=9606 GN=CGGBP1 PE=1 SV=2"	"0.000"	""	"12"	"2"	"3"	"2"	"167"	"18.8"	"8.95"	"360.97"	"5.30"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"8545"	"ENSG00000163320"	"CGGBP1"	"D3DU38; hsa:8545; O15183; Q9UFW8"	""	""	"0"	"0"	"100.3"	"105.0"	"112.9"	"132.4"	"107.3"	"94.7"	"152.5"	"161.2"	"238.7"	"475.9"	"594.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15439"	"Multidrug resistance-associated protein 4 OS=Homo sapiens OX=9606 GN=ABCC4 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"1325"	"149.4"	"8.19"	"616.72"	"5.29"	"2"	"2"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"10257"	"ENSG00000125257"	"ABCC4"	"A9Z1Z7; B7Z3Q7; hsa:10257; O15439; Q8IVZ4; Q8IZN6; Q8NEW8; Q9Y6J2"	"Fluoropyrimidine activity; Androgen receptor network in prostate cancer; Drug induction of bile acid pathway; Ectoderm differentiation; Pregnane X receptor pathway; Nuclear receptors meta-pathway; NRF2 pathway; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; TYROBP causal network in microglia; Aspirin and miRNAs; Proximal tubule transport; FOXA2 pathway; Prostaglandin synthesis and regulation"	"ABC-family proteins mediated transport; Paracetamol ADME; Platelet degranulation ; Azathioprine ADME"	"17"	"0"	"14.4"	"21.2"	"25.6"	"32.1"	"16.8"	"22.4"	"48.3"	"60.6"	"102.3"	"194.4"	"224.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42695"	"Condensin-2 complex subunit D3 OS=Homo sapiens OX=9606 GN=NCAPD3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"4"	"1"	"1498"	"168.8"	"7.50"	"723.90"	"5.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf12717"	"23310"	"ENSG00000151503"	"NCAPD3"	"A6NFS2; hsa:23310; P42695; Q4KMQ9"	""	"Condensation of Prophase Chromosomes"	"1"	"0"	"5.8"	"6.9"	"12.3"	"12.7"	"8.4"	"8.9"	"17.6"	"14.9"	"29.7"	"67.8"	"95.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5D862"	"Filaggrin-2 OS=Homo sapiens OX=9606 GN=FLG2 PE=1 SV=1"	"0.000"	""	"0"	"1"	"4"	"1"	"2391"	"247.9"	"8.31"	"564.23"	"5.28"	"1"	"1"	"cell adhesion;other biological processes"	"non-structural extracellular;plasma membrane;other cell component"	"other molecular function"	"Pf01023"	"388698"	"ENSG00000143520"	"FLG2"	"hsa:388698; Q5D862; Q9H4U1"	""	"Neutrophil degranulation"	"1"	"0"	"57.2"	"58.9"	"205.8"	"31.1"	"15.1"	"19.3"	"67.9"	"62.4"	"82.8"	"150.9"	"155.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99719"	"Septin-5 OS=Homo sapiens OX=9606 GN=SEPTIN5 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"369"	"42.8"	"6.67"	"506.90"	"5.27"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"other molecular function"	"Pf00735"	"5413"	"ENSG00000184702"	"SEPTIN5"	"hsa:5413; O15251; Q96MY5; Q99719"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway; 22q11.2 copy number variation syndrome"	""	"3"	"0"	"7.3"	"6.7"	"9.7"	"15.7"	"8.2"	"8.5"	"20.6"	"24.1"	"27.6"	"55.6"	"64.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46779"	"60S ribosomal protein L28 OS=Homo sapiens OX=9606 GN=RPL28 PE=1 SV=3"	"0.000"	""	"13"	"2"	"4"	"2"	"137"	"15.7"	"12.02"	"595.61"	"5.27"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01778"	"6158"	"ENSG00000108107"	"RPL28"	"B2R4A6; B4DEP9; C9JB50; E9PB24; G5E9L2; hsa:6158; P46779; Q6IAY0; Q96FX1; Q9BWQ0"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"150.4"	"150.5"	"162.2"	"205.5"	"138.7"	"138.6"	"245.7"	"266.0"	"354.7"	"952.1"	"1553.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UBQ7"	"Glyoxylate reductase/hydroxypyruvate reductase OS=Homo sapiens OX=9606 GN=GRHPR PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"328"	"35.6"	"7.39"	""	"5.27"	""	"1"	"other metabolic processes"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00389, Pf02826"	"9380"	"ENSG00000137106"	"GRHPR"	"hsa:9380; Q5T945; Q9H3E9; Q9H636; Q9UBQ7; Q9UKX1"	""	"Glyoxylate metabolism and glycine degradation"	"1"	"0"	"0.0"	"3.4"	"2.4"	"5.9"	"0.0"	"0.0"	"3.6"	"3.1"	"9.0"	"58.9"	"116.3"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5PSV4"	"Breast cancer metastasis-suppressor 1-like protein OS=Homo sapiens OX=9606 GN=BRMS1L PE=1 SV=2"	"0.000"	""	"6"	"2"	"3"	"2"	"323"	"37.6"	"5.15"	"328.08"	"5.27"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf08598"	"84312"	"ENSG00000100916"	"BRMS1L"	"A6NFW5; A6NH45; B2RD65; hsa:84312; Q5PSV4; Q9BRI4"	""	""	"0"	"0"	"183.9"	"154.6"	"201.5"	"225.7"	"140.0"	"128.8"	"299.1"	"352.7"	"394.9"	"1010.8"	"1391.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5B6"	"PAX3- and PAX7-binding protein 1 OS=Homo sapiens OX=9606 GN=PAXBP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"917"	"104.7"	"5.68"	"418.89"	"5.27"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf07842"	"94104"	"ENSG00000159086; ENSG00000263141"	"PAXBP1"	"D3DSE7; hsa:94104; Q96DU8; Q9NYQ0; Q9Y5B6"	""	""	"0"	"0"	"34.7"	"28.6"	"47.5"	"45.1"	"29.9"	"35.2"	"49.8"	"52.7"	"60.9"	"132.4"	"210.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92734"	"Protein TFG OS=Homo sapiens OX=9606 GN=TFG PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"400"	"43.4"	"5.10"	"528.36"	"5.26"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00564"	"10342"	"ENSG00000114354"	"TFG"	"D3DN49; G5E9V1; hsa:10342; K0J5S8; K0J6K2; Q15656; Q92734; Q969I2"	""	"Signaling by ALK fusions and activated point mutants; COPII-mediated vesicle transport"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75691"	"Small subunit processome component 20 homolog OS=Homo sapiens OX=9606 GN=UTP20 PE=1 SV=3"	""	""	"1"	"1"	"2"	"1"	"2785"	"318.2"	"7.39"	""	"5.25"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	""	"Pf07539, Pf20416"	"27340"	"ENSG00000120800"	"UTP20"	"hsa:27340; O75691; Q9H3H4"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"232.5"	"61.6"	"398.9"	"367.0"	"266.6"	"291.4"	"328.2"	"286.6"	"346.4"	"597.3"	"1362.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36957"	"Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial OS=Homo sapiens OX=9606 GN=DLST PE=1 SV=4"	"0.000"	""	"4"	"2"	"4"	"2"	"453"	"48.7"	"8.95"	"558.07"	"5.23"	"2"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00198, Pf00364"	"1743"	"ENSG00000119689"	"DLST"	"B7Z5W8; E7ESY5; hsa:1743; P36957; Q7LDY7; Q9BQ32"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Metabolic reprogramming in colon cancer; 7q11.23 copy number variation syndrome; 1p36 copy number variation syndrome; 10q11.21q11.23 copy number variation syndrome; TCA cycle (aka Krebs or citric acid cycle)"	"Glyoxylate metabolism and glycine degradation; Lysine catabolism; Citric acid cycle (TCA cycle)"	"10"	"0"	"243.0"	"168.0"	"264.0"	"294.7"	"194.1"	"224.7"	"280.8"	"283.9"	"306.1"	"536.3"	"686.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVH2"	"Integrator complex subunit 7 OS=Homo sapiens OX=9606 GN=INTS7 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"962"	"106.8"	"8.02"	"436.71"	"5.23"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	""	"25896"	"ENSG00000143493"	"INTS7"	"B4DLZ6; B7WNP6; B7WPB6; hsa:25896; Q8N4K7; Q8WUH5; Q9H9V3; Q9NVH2; Q9NVU5; Q9UFC6; Q9UFM3"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"26.0"	"24.7"	"32.9"	"37.4"	"28.5"	"21.2"	"45.6"	"36.4"	"56.5"	"119.4"	"137.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60673"	"DNA polymerase zeta catalytic subunit OS=Homo sapiens OX=9606 GN=REV3L PE=1 SV=2"	"0.000"	""	"1"	"2"	"4"	"1"	"3130"	"352.6"	"8.47"	"535.33"	"5.23"	"2"	"2"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf14260, Pf15735"	"5980"	"ENSG00000009413"	"REV3L"	"hsa:5980; O43214; O60673; Q5TC33"	"DNA repair pathways, full network"	"Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI"	"4"	"0"	"9.7"	"7.0"	"8.6"	"11.0"	"8.9"	"4.7"	"8.2"	"10.9"	"7.5"	"18.1"	"24.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQC8"	"Intraflagellar transport protein 46 homolog OS=Homo sapiens OX=9606 GN=IFT46 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"304"	"34.3"	"4.54"	"460.03"	"5.22"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	""	"Pf12317"	"56912"	"ENSG00000118096"	"IFT46"	"A8K0F6; hsa:56912; Q9H6V5; Q9NQC8"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR)"	"Intraflagellar transport"	"4"	"0"	"7.8"	"7.9"	"14.4"	"17.5"	"11.3"	"11.6"	"28.0"	"26.9"	"24.9"	"101.4"	"159.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28072"	"Proteasome subunit beta type-6 OS=Homo sapiens OX=9606 GN=PSMB6 PE=1 SV=4"	"0.000"	""	"8"	"2"	"3"	"2"	"239"	"25.3"	"4.92"	"374.84"	"5.22"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5694"	"ENSG00000142507"	"PSMB6"	"hsa:5694; P28072; Q96J55"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"66.8"	"64.0"	"92.2"	"133.9"	"78.6"	"97.5"	"145.4"	"119.4"	"161.4"	"344.4"	"578.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NY61"	"Protein AATF OS=Homo sapiens OX=9606 GN=AATF PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"560"	"63.1"	"4.94"	"439.43"	"5.22"	"1"	"1"	"cell adhesion;stress response;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf08164, Pf13339"	"26574"	"ENSG00000275700; ENSG00000276072"	"AATF"	"A6NCJ6; B3KQ26; hsa:26574; Q9NY61; Q9P0A4; Q9UNX5"	"17q12 copy number variation syndrome"	"NRAGE signals death through JNK"	"2"	"0"	"36.3"	"42.7"	"40.6"	"61.8"	"31.3"	"43.8"	"66.8"	"73.4"	"104.2"	"278.9"	"406.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q76FK4"	"Nucleolar protein 8 OS=Homo sapiens OX=9606 GN=NOL8 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"1167"	"131.5"	"7.09"	"294.68"	"5.22"	"1"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00076"	"55035"	"ENSG00000198000"	"NOL8"	"hsa:55035; Q5TCC7; Q5TCC8; Q5TCD3; Q5TCD5; Q5TCD6; Q5TCD7; Q76D35; Q76FK4; Q7L3E2; Q9H586; Q9H795; Q9H7W7; Q9H9J6; Q9NWA4; Q9NWM4"	""	""	"0"	"0"	"320.1"	"286.7"	"311.9"	"347.6"	"275.7"	"278.2"	"380.8"	"372.1"	"435.8"	"559.0"	"626.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43432"	"Eukaryotic translation initiation factor 4 gamma 3 OS=Homo sapiens OX=9606 GN=EIF4G3 PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"1"	"1585"	"176.5"	"5.38"	"383.37"	"5.22"	"1"	"2"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity"	"Pf02020, Pf02847, Pf02854"	"8672"	"ENSG00000075151"	"EIF4G3"	"B9EGQ7; hsa:8672; O43432; Q15597; Q504Z1; Q5SWC3; Q8NEN1"	"Translation factors; Translation inhibitors in chronically activated PDGFRA cells"	"ISG15 antiviral mechanism"	"3"	"0"	"16.3"	"9.7"	"22.0"	"25.2"	"11.0"	"15.9"	"36.3"	"30.3"	"55.8"	"160.6"	"201.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9HAV4"	"Exportin-5 OS=Homo sapiens OX=9606 GN=XPO5 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"1204"	"136.2"	"5.80"	""	"5.22"	""	"1"	"RNA metabolism OR transcription;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08389, Pf19273"	"57510"	"ENSG00000124571"	"XPO5"	"hsa:57510; Q5JTE6; Q96G48; Q96HN3; Q9BWM6; Q9BZV5; Q9H9M4; Q9HAV4; Q9NT89; Q9NW39; Q9ULC9"	"miRNA biogenesis; exRNA mechanism of action and biogenesis; Primary ovarian insufficiency"	"MicroRNA (miRNA) biogenesis"	"4"	"0"	"15.8"	"13.1"	"19.3"	"17.5"	"12.5"	"16.5"	"25.7"	"27.9"	"37.0"	"98.8"	"131.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UMN6"	"Histone-lysine N-methyltransferase 2B OS=Homo sapiens OX=9606 GN=KMT2B PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"2715"	"293.3"	"8.22"	"593.72"	"5.21"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"9757"	"ENSG00000272333"	"KMT2B"	"O15022; O95836; Q96GP2; Q96IP3; Q9UK25; Q9UMN6; Q9Y668; Q9Y669"	"Histone modifications"	"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Formation of WDR5-containing histone-modifying complexes; PKMTs methylate histone lysines"	"4"	"0"	"49.7"	"36.9"	"52.1"	"60.1"	"50.6"	"47.4"	"81.4"	"77.1"	"98.7"	"262.4"	"369.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2S6"	"Translation machinery-associated protein 7 OS=Homo sapiens OX=9606 GN=TMA7 PE=1 SV=1"	"0.000"	""	"25"	"3"	"5"	"2"	"64"	"7.1"	"9.99"	"1086.77"	"5.21"	"3"	"2"	""	""	""	"Pf09072"	"51372"	"ENSG00000232112"	"TMA7"	"hsa:51372; Q9P052; Q9Y2S6"	""	""	"0"	"1"	"916.3"	"826.1"	"1003.7"	"991.8"	"695.9"	"750.0"	"1117.7"	"1113.5"	"1297.3"	"1173.9"	"1034.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15542"	"Transcription initiation factor TFIID subunit 5 OS=Homo sapiens OX=9606 GN=TAF5 PE=1 SV=3"	"0.000"	""	"2"	"2"	"4"	"2"	"800"	"86.8"	"5.64"	"692.49"	"5.21"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04494"	"6877"	"ENSG00000148835"	"TAF5"	"A8K5B4; B2RMR0; B7ZKJ6; hsa:6877; Q15542; Q53EM4; Q5SYD5; Q86UZ7; Q9Y4K5"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"11"	"0"	"130.9"	"119.8"	"131.9"	"145.9"	"103.3"	"121.3"	"190.1"	"214.7"	"236.1"	"568.1"	"772.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13405"	"39S ribosomal protein L49, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL49 PE=1 SV=1"	"0.000"	""	"7"	"1"	"4"	"1"	"166"	"19.2"	"9.45"	"587.79"	"5.20"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05046"	"740"	"ENSG00000149792"	"MRPL49"	"B2R4G6; hsa:740; Q13405"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"58.4"	"55.4"	"71.0"	"89.1"	"57.1"	"54.1"	"91.8"	"107.7"	"123.8"	"232.3"	"317.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q10586"	"D site-binding protein OS=Homo sapiens OX=9606 GN=DBP PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"325"	"34.3"	"9.29"	"676.95"	"5.19"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07716"	"1628"	"ENSG00000105516"	"DBP"	"A2I2P4; hsa:1628; Q10586"	"Orexin receptor pathway"	"BMAL1:CLOCK,NPAS2 activates circadian gene expression"	"2"	"0"	"19.6"	"23.5"	"21.6"	"24.8"	"20.9"	"15.2"	"24.0"	"24.2"	"29.9"	"70.2"	"82.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6GYQ0"	"Ral GTPase-activating protein subunit alpha-1 OS=Homo sapiens OX=9606 GN=RALGAPA1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"2036"	"229.7"	"6.19"	"423.54"	"5.19"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02145, Pf20412"	"253959"	"ENSG00000174373"	"RALGAPA1"	"A6NMA4; B9EK38; C5NU19; hsa:253959; O94960; Q6GYP9; Q6GYQ0; Q6ZT23; Q86YF3; Q86YF5; Q8ND69"	""	"RHOH GTPase cycle"	"1"	"0"	"16.5"	"10.1"	"18.8"	"18.0"	"16.7"	"13.8"	"46.9"	"40.5"	"63.5"	"105.7"	"157.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBC2"	"Epidermal growth factor receptor substrate 15-like 1 OS=Homo sapiens OX=9606 GN=EPS15L1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"864"	"94.2"	"5.11"	"539.58"	"5.18"	"2"	"2"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"58513"	"ENSG00000127527"	"EPS15L1"	"A2RRF3; A5PL29; B4DKA3; hsa:58513; Q9UBC2"	"EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation"	"4"	"0"	"28.7"	"18.4"	"24.5"	"34.7"	"21.7"	"20.2"	"43.0"	"44.2"	"47.2"	"122.4"	"185.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRL2"	"Bromodomain adjacent to zinc finger domain protein 1A OS=Homo sapiens OX=9606 GN=BAZ1A PE=1 SV=2"	"0.000"	""	"2"	"3"	"3"	"3"	"1556"	"178.6"	"6.60"	"328.01"	"5.17"	"1"	"2"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf02791, Pf10537, Pf15612, Pf15613"	"11177"	"ENSG00000198604"	"BAZ1A"	"hsa:11177; Q9NRL2; Q9NZ15; Q9P065; Q9UIG1; Q9Y3V3"	"Ectoderm differentiation"	""	"1"	"0"	"122.8"	"107.0"	"140.8"	"171.1"	"110.8"	"120.1"	"218.5"	"236.5"	"359.9"	"1005.7"	"1414.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NP97"	"Dynein light chain roadblock-type 1 OS=Homo sapiens OX=9606 GN=DYNLRB1 PE=1 SV=3"	"0.000"	""	"17"	"1"	"2"	"1"	"96"	"10.9"	"7.25"	"537.06"	"5.16"	"1"	"1"	"other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03259"	"83658"	"ENSG00000125971"	"DYNLRB1"	"B1AKR5; hsa:83658; Q5TC72; Q96IV3; Q9NP97; Q9NQM2"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; 3q29 copy number variation syndrome"	"Intraflagellar transport"	"4"	"0"	"46.4"	"55.8"	"59.7"	"69.6"	"53.4"	"48.0"	"73.0"	"73.3"	"102.8"	"204.3"	"295.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60002"	"Transcription elongation factor 1 homolog OS=Homo sapiens OX=9606 GN=ELOF1 PE=1 SV=1"	""	""	"22"	"1"	"1"	"1"	"83"	"9.5"	"8.00"	""	"5.14"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf05129"	"84337"	"ENSG00000130165"	"ELOF1"	"hsa:84337; P60002; Q8R1J7; Q96II4"	""	""	"0"	"0"	"48.3"	"35.1"	"39.6"	"54.3"	"34.9"	"40.8"	"98.5"	"119.0"	"168.7"	"203.9"	"123.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4W1"	"L-xylulose reductase OS=Homo sapiens OX=9606 GN=DCXR PE=1 SV=2"	"0.000"	""	"7"	"2"	"4"	"2"	"244"	"25.9"	"8.10"	"691.54"	"5.13"	"2"	"2"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf13561"	"51181"	"ENSG00000169738"	"DCXR"	"hsa:51181; Q7Z4W1; Q9BTZ3; Q9UHY9"	""	"Formation of xylulose-5-phosphate; Essential pentosuria"	"2"	"0"	"224.9"	"188.7"	"238.3"	"271.3"	"199.5"	"212.1"	"303.4"	"315.2"	"441.5"	"913.3"	"1103.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UK59"	"Lariat debranching enzyme OS=Homo sapiens OX=9606 GN=DBR1 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"544"	"61.5"	"5.47"	""	"5.13"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"other molecular function"	"Pf00149, Pf05011"	"51163"	"ENSG00000138231"	"DBR1"	"hsa:51163; Q96GH0; Q9NXQ6; Q9UK59"	""	""	"0"	"0"	"7.7"	"9.9"	"9.7"	"12.2"	"11.6"	"7.2"	"18.2"	"16.1"	"28.8"	"50.9"	"77.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75396"	"Vesicle-trafficking protein SEC22b OS=Homo sapiens OX=9606 GN=SEC22B PE=1 SV=4"	"0.000"	""	"14"	"2"	"2"	"2"	"215"	"24.6"	"6.92"	"273.57"	"5.13"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"41.9"	"43.0"	"60.3"	"77.6"	"56.2"	"45.8"	"101.9"	"110.4"	"160.4"	"466.4"	"635.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14373"	"Zinc finger protein RFP OS=Homo sapiens OX=9606 GN=TRIM27 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"513"	"58.5"	"6.21"	"691.25"	"5.12"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00622, Pf00643, Pf13765, Pf15227"	"5987"	"ENSG00000204713; ENSG00000215641; ENSG00000229006; ENSG00000234495; ENSG00000237071"	"TRIM27"	"A2BE15; hsa:5987; P14373; Q5RJA8; Q5ST26; Q6LA73; Q6NXR9; Q9BZY6; Q9UJL3"	""	"Regulation of PTEN stability and activity; SUMOylation of ubiquitinylation proteins; Suppression of apoptosis"	"3"	"0"	"93.6"	"65.5"	"104.0"	"113.4"	"79.3"	"62.9"	"124.9"	"124.8"	"154.3"	"217.2"	"347.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61353"	"60S ribosomal protein L27 OS=Homo sapiens OX=9606 GN=RPL27 PE=1 SV=2"	"0.000"	""	"13"	"3"	"5"	"3"	"136"	"15.8"	"10.56"	"1010.84"	"5.09"	"3"	"2"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf00467, Pf01777"	"6155"	"ENSG00000131469"	"RPL27"	"hsa:6155; P08526; P61353; Q4G0A9"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"356.4"	"384.7"	"487.3"	"601.8"	"389.9"	"417.7"	"645.4"	"665.9"	"811.7"	"1667.4"	"2527.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CZ6"	"HAUS augmin-like complex subunit 3 OS=Homo sapiens OX=9606 GN=HAUS3 PE=1 SV=1"	"0.000"	""	"3"	"2"	"4"	"2"	"603"	"69.6"	"5.55"	"536.96"	"5.09"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	"Pf14932"	"79441"	"ENSG00000214367"	"HAUS3"	"B4DF64; hsa:79441; O43606; Q68CZ6; Q8TAZ5; Q9BTJ9"	""	"Regulation of PLK1 Activity at G2/M Transition; Recruitment of NuMA to mitotic centrosomes; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"20.4"	"21.3"	"19.6"	"31.3"	"24.0"	"21.3"	"30.0"	"44.1"	"50.8"	"113.2"	"142.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q567U6"	"Coiled-coil domain-containing protein 93 OS=Homo sapiens OX=9606 GN=CCDC93 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"631"	"73.2"	"8.15"	"433.21"	"5.09"	"1"	"1"	"transport"	"other cytoplasmic organelle;other cell component"	""	"Pf09762"	"54520"	"ENSG00000125633"	"CCDC93"	"A8K3V7; hsa:54520; Q4LE78; Q53TJ2; Q567U6; Q8TBX5; Q9H6R5; Q9NV15"	""	""	"0"	"0"	"32.2"	"23.0"	"35.4"	"33.9"	"25.4"	"28.6"	"35.1"	"45.0"	"45.2"	"82.4"	"140.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKD2"	"mRNA turnover protein 4 homolog OS=Homo sapiens OX=9606 GN=MRTO4 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"239"	"27.5"	"8.29"	"444.05"	"5.09"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00466, Pf17777"	"51154"	"ENSG00000053372"	"MRTO4"	"B3KNB3; hsa:51154; Q5TG55; Q96SS6; Q9BPV9; Q9UKD2"	""	""	"0"	"0"	"18.5"	"14.8"	"20.0"	"29.0"	"20.4"	"17.8"	"46.3"	"47.6"	"58.6"	"160.1"	"258.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75044"	"SLIT-ROBO Rho GTPase-activating protein 2 OS=Homo sapiens OX=9606 GN=SRGAP2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"1071"	"120.8"	"6.70"	"519.37"	"5.09"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf00611, Pf00620"	"23380"	"ENSG00000266028"	"SRGAP2"	"A2RUF3; hsa:23380; O75044"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate Formins; RAC3 GTPase cycle; RHOF GTPase cycle; RHOU GTPase cycle; Inactivation of CDC42 and RAC1"	"8"	"0"	"27.8"	"12.6"	"57.4"	"40.0"	"20.6"	"31.0"	"33.2"	"33.1"	"48.3"	"66.7"	"82.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43488"	"Aflatoxin B1 aldehyde reductase member 2 OS=Homo sapiens OX=9606 GN=AKR7A2 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"359"	"39.6"	"7.17"	"456.14"	"5.07"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00248"	"8574"	"ENSG00000053371"	"AKR7A2"	"hsa:8574; O43488; O75749; Q5TG63"	"Aflatoxin B1 metabolism; Metapathway biotransformation Phase I and II"	"Aflatoxin activation and detoxification"	"3"	"0"	"47.0"	"33.8"	"71.0"	"87.6"	"45.6"	"50.4"	"93.8"	"91.3"	"111.6"	"362.1"	"629.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P31040"	"Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHA PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"664"	"72.6"	"7.39"	"594.85"	"5.07"	"2"	"2"	"other metabolic processes;developmental processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00890, Pf02910"	"6389"	"ENSG00000073578"	"SDHA"	"A8K5J6; B4DJ60; E9PBJ5; hsa:6389; P31040; Q16395; Q59GW8; Q8IW48; Q9UMY5"	"Electron transport chain: OXPHOS system in mitochondria; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Amino acid metabolism; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; Arsenic metabolism and reactive oxygen species generation; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"9"	"0"	"211.8"	"220.4"	"230.0"	"240.9"	"174.6"	"196.1"	"316.1"	"295.3"	"401.6"	"690.9"	"771.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q16543"	"Hsp90 co-chaperone Cdc37 OS=Homo sapiens OX=9606 GN=CDC37 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"378"	"44.4"	"5.25"	""	"5.06"	""	"1"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf03234, Pf08564, Pf08565"	"11140"	"ENSG00000105401"	"CDC37"	"hsa:11140; Q16543; Q53YA2"	"TNF-alpha signaling pathway; Aryl hydrocarbon receptor pathway; Aryl hydrocarbon receptor pathway; Nuclear receptors meta-pathway; Interactions between LOXL4 and oxidative stress pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"Regulation of necroptotic cell death; Downregulation of ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; RHOBTB2 GTPase cycle; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; Constitutive Signaling by Overexpressed ERBB2; Drug-mediated inhibition of ERBB2 signaling; Resistance of ERBB2 KD mutants to trastuzumab; Resistance of ERBB2 KD mutants to sapitinib; Resistance of ERBB2 KD mutants to tesevatinib; Resistance of ERBB2 KD mutants to neratinib; Resistance of ERBB2 KD mutants to osimertinib; Resistance of ERBB2 KD mutants to afatinib; Resistance of ERBB2 KD mutants to AEE788; Resistance of ERBB2 KD mutants to lapatinib; Drug resistance in ERBB2 TMD/JMD mutants"	"27"	"0"	"51.9"	"52.2"	"56.4"	"106.0"	"61.4"	"52.0"	"98.3"	"106.2"	"115.7"	"273.4"	"363.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00399"	"Dynactin subunit 6 OS=Homo sapiens OX=9606 GN=DCTN6 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"190"	"20.7"	"6.32"	"477.47"	"5.06"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"10671"	"ENSG00000104671"	"DCTN6"	"B2RAC1; hsa:10671; O00399"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	"4"	"0"	"34.4"	"28.5"	"38.4"	"47.6"	"34.6"	"29.2"	"64.1"	"66.3"	"96.8"	"257.7"	"400.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55011"	"Solute carrier family 12 member 2 OS=Homo sapiens OX=9606 GN=SLC12A2 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"1"	"1212"	"131.4"	"6.40"	"713.19"	"5.05"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"transporter activity;other molecular function"	"Pf00324, Pf03522, Pf08403"	"6558"	"ENSG00000064651"	"SLC12A2"	"hsa:6558; P55011; Q8N713; Q8WWH7"	""	"Cation-coupled Chloride cotransporters"	"1"	"0"	"34.1"	"26.2"	"39.8"	"42.4"	"26.5"	"25.0"	"59.9"	"57.7"	"76.8"	"172.5"	"264.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGP8"	"Translocation protein SEC63 homolog OS=Homo sapiens OX=9606 GN=SEC63 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"760"	"87.9"	"5.31"	"481.06"	"5.04"	"1"	"1"	"other metabolic processes;transport;developmental processes"	"other membranes;ER/Golgi"	"transporter activity;other molecular function"	"Pf00226, Pf02889"	"11231"	"ENSG00000025796"	"SEC63"	"hsa:11231; O95380; Q5THN4; Q86VS9; Q8IWL0; Q9NTE0; Q9UGP8"	""	""	"0"	"0"	"38.4"	"34.0"	"40.3"	"57.9"	"36.3"	"33.0"	"63.0"	"76.6"	"101.6"	"344.2"	"562.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UKD1"	"Glucocorticoid modulatory element-binding protein 2 OS=Homo sapiens OX=9606 GN=GMEB2 PE=1 SV=1"	""	""	"6"	"2"	"2"	"2"	"530"	"56.4"	"5.60"	""	"5.04"	""	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01342"	"26205"	"ENSG00000101216"	"GMEB2"	"E1P5J3; hsa:26205; Q5TDS0; Q9H431; Q9H4X7; Q9H4X8; Q9UF78; Q9UKD1; Q9ULF1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TE49"	"OTU domain-containing protein 7A OS=Homo sapiens OX=9606 GN=OTUD7A PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"926"	"100.6"	"8.40"	"507.03"	"5.04"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01754, Pf02338, Pf14555"	"161725"	"ENSG00000169918"	"OTUD7A"	"hsa:161725; Q8IWK5; Q8TE49"	"15q13.3 copy number variation syndrome; 15q11q13 copy number variation"	"Ovarian tumor domain proteases"	"3"	"0"	"3.9"	"3.1"	"2.5"	"6.0"	"1.9"	"4.5"	"11.6"	"8.4"	"19.7"	"88.6"	"119.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02543"	"60S ribosomal protein L18a OS=Homo sapiens OX=9606 GN=RPL18A PE=1 SV=2"	"0.000"	""	"10"	"2"	"3"	"2"	"176"	"20.7"	"10.71"	"338.72"	"5.03"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01775"	"6142"	"ENSG00000105640"	"RPL18A"	"hsa:6142; Q02543"	"VEGFA-VEGFR2 signaling; Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"15"	"0"	"206.3"	"247.2"	"269.0"	"297.2"	"221.4"	"221.3"	"343.6"	"372.2"	"446.3"	"943.2"	"1611.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25789"	"Proteasome subunit alpha type-4 OS=Homo sapiens OX=9606 GN=PSMA4 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"2"	"261"	"29.5"	"7.72"	"308.62"	"5.03"	"1"	"2"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5685"	"ENSG00000041357"	"PSMA4"	"D3DW86; hsa:5685; P25789; Q53XP2; Q567Q5; Q8TBD1"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Exercise-induced circadian regulation; Alzheimer's disease"	"MAPK6/MAPK4 signaling; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"78.7"	"86.1"	"109.8"	"122.3"	"89.0"	"99.2"	"148.4"	"151.8"	"186.9"	"508.7"	"917.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEY8"	"Periphilin-1 OS=Homo sapiens OX=9606 GN=PPHLN1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"458"	"52.7"	"9.11"	"337.47"	"5.02"	"1"	"2"	"cell organization and biogenesis;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	""	"Pf11488"	"51535"	"ENSG00000134283"	"PPHLN1"	"E9PAX8; hsa:51535; Q86YT2; Q8IXN3; Q8NEY8; Q8TB09; Q96NB9; Q9NXL4; Q9P0P6; Q9P0R9"	""	""	"0"	"0"	"594.4"	"561.7"	"622.3"	"714.2"	"551.3"	"601.2"	"698.2"	"708.7"	"735.6"	"1338.8"	"1968.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NF91"	"Nesprin-1 OS=Homo sapiens OX=9606 GN=SYNE1 PE=1 SV=4"	"0.000"	""	"0"	"4"	"5"	"2"	"8797"	"1010.5"	"5.53"	"776.72"	"5.02"	"3"	"2"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf10541"	"23345"	"ENSG00000131018"	"SYNE1"	"B3W695; E7EQI5; H0Y4C0; hsa:23345; O94890; Q3ZCV0; Q5JV19; Q5JV22; Q8N9P7; Q8NF91; Q8TCP1; Q8WWW6; Q8WWW7; Q8WXF6; Q96N17; Q9C0A7; Q9H525; Q9H526; Q9NS36; Q9NU50; Q9UJ06; Q9UJ07; Q9ULF8"	"Envelope proteins and their potential roles in EDMD physiopathology"	"Meiotic synapsis"	"2"	"0"	"48.5"	"36.5"	"75.9"	"83.9"	"49.1"	"59.4"	"94.7"	"86.8"	"147.8"	"543.4"	"818.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P08574"	"Cytochrome c1, heme protein, mitochondrial OS=Homo sapiens OX=9606 GN=CYC1 PE=1 SV=3"	""	""	"7"	"1"	"1"	"1"	"325"	"35.4"	"9.00"	""	"5.02"	""	"1"	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf02167"	"1537"	"ENSG00000179091"	"CYC1"	"hsa:1537; P08574; Q5U062; Q6FHS7"	"Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport; Mitochondrial protein import"	"4"	"0"	"25.9"	"32.4"	"34.7"	"47.7"	"38.6"	"32.1"	"50.1"	"52.7"	"75.4"	"139.8"	"198.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50213"	"Isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=IDH3A PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"366"	"39.6"	"6.92"	"309.23"	"5.00"	"1"	"2"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00180"	"3419"	"ENSG00000166411"	"IDH3A"	"D3DW83; hsa:3419; P50213; Q9H3X0"	"TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Metabolic reprogramming in colon cancer; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle)"	"4"	"0"	"115.2"	"95.9"	"132.8"	"126.7"	"86.6"	"107.0"	"164.6"	"155.9"	"201.8"	"869.3"	"1750.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68D10"	"Protein SPT2 homolog OS=Homo sapiens OX=9606 GN=SPTY2D1 PE=1 SV=3"	"0.001"	""	"3"	"1"	"2"	"1"	"685"	"75.6"	"9.79"	"231.19"	"5.00"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08243"	"144108"	"ENSG00000179119"	"SPTY2D1"	"hsa:144108; Q68D10; Q6AWA5; Q6MZI5; Q7Z390; Q7Z470; Q86VG8; Q8N3E7; Q8N417; Q8N8I3"	""	""	"0"	"0"	"30.2"	"28.7"	"38.2"	"39.6"	"31.0"	"38.2"	"41.7"	"53.0"	"64.2"	"139.2"	"156.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15545"	"Transcription initiation factor TFIID subunit 7 OS=Homo sapiens OX=9606 GN=TAF7 PE=1 SV=1"	"0.000"	""	"7"	"2"	"4"	"2"	"349"	"40.2"	"5.20"	"661.23"	"5.00"	"2"	"2"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04658"	"6879"	"ENSG00000178913"	"TAF7"	"B2RBV9; hsa:6879; Q13036; Q15545"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Regulation of TP53 Activity through Phosphorylation"	"10"	"0"	"135.9"	"128.3"	"212.6"	"231.8"	"155.3"	"172.0"	"243.3"	"275.0"	"282.6"	"480.2"	"473.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15843"	"NEDD8 OS=Homo sapiens OX=9606 GN=NEDD8 PE=1 SV=1"	"0.000"	""	"17"	"1"	"2"	"1"	"81"	"9.1"	"8.43"	"531.06"	"5.00"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00240"	"4738"	"ENSG00000129559; ENSG00000285246"	"NEDD8"	"hsa:4738; Q15843; Q3SXN8; Q6LES6"	"EGF/EGFR signaling pathway; 2q37 copy number variation syndrome"	"Cargo recognition for clathrin-mediated endocytosis; Neddylation; UCH proteinases; Iron uptake and transport; TGF-beta receptor signaling activates SMADs"	"7"	"0"	"58.6"	"54.9"	"83.1"	"130.8"	"53.3"	"64.3"	"87.4"	"90.9"	"107.1"	"316.6"	"567.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8W3"	"Protein FAM204A OS=Homo sapiens OX=9606 GN=FAM204A PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"233"	"27.0"	"7.91"	"470.01"	"4.99"	"1"	"1"	""	""	""	""	"63877"	"ENSG00000165669"	"FAM204A"	"D3DRC6; hsa:63877; Q5T373; Q9H5V5; Q9H8W3"	""	""	"0"	"0"	"59.3"	"53.0"	"77.1"	"84.6"	"60.4"	"63.8"	"81.2"	"96.1"	"104.0"	"161.4"	"175.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16851"	"UTP--glucose-1-phosphate uridylyltransferase OS=Homo sapiens OX=9606 GN=UGP2 PE=1 SV=5"	"0.000"	""	"3"	"1"	"2"	"1"	"508"	"56.9"	"8.15"	"434.62"	"4.98"	"1"	"1"	"other metabolic processes;developmental processes"	"cytosol;other cell component"	"other molecular function"	"Pf01704"	"7360"	"ENSG00000169764"	"UGP2"	"hsa:7360; Q07131; Q0P6K2; Q16851; Q86Y81; Q9BU15"	"Exercise-induced circadian regulation; Glycogen synthesis and degradation; Glucuronidation"	"Glycogen synthesis; Formation of the active cofactor, UDP-glucuronate"	"5"	"0"	"98.6"	"98.6"	"80.0"	"95.0"	"80.5"	"98.3"	"126.3"	"120.1"	"145.3"	"224.1"	"351.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXC6"	"COP9 signalosome complex subunit 9 OS=Homo sapiens OX=9606 GN=COPS9 PE=1 SV=3"	"0.000"	""	"35"	"1"	"2"	"1"	"57"	"6.2"	"3.83"	"455.53"	"4.98"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	""	"Pf15004"	"150678"	"ENSG00000172428"	"COPS9"	"hsa:150678; Q8N110; Q8WXC6"	"2q37 copy number variation syndrome"	""	"1"	"0"	"5.2"	"2.3"	"6.4"	"4.8"	"5.2"	"5.9"	"9.9"	"10.4"	"15.1"	"45.6"	"76.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05386"	"60S acidic ribosomal protein P1 OS=Homo sapiens OX=9606 GN=RPLP1 PE=1 SV=1"	"0.000"	""	"34"	"3"	"6"	"2"	"114"	"11.5"	"4.32"	"1784.85"	"4.98"	"3"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00428"	"6176"	"ENSG00000137818"	"RPLP1"	"A6NIB2; hsa:6176; P05386"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"275.0"	"231.3"	"353.2"	"513.0"	"272.0"	"215.5"	"496.6"	"493.2"	"636.5"	"1563.8"	"2374.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BW85"	"Splicing factor YJU2 OS=Homo sapiens OX=9606 GN=YJU2 PE=1 SV=1"	"0.000"	""	"10"	"2"	"3"	"2"	"323"	"37.1"	"5.92"	"1178.03"	"4.97"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf04502"	"55702"	"ENSG00000105248"	"YJU2"	"hsa:55702; O75270; Q9BW85; Q9H862; Q9NW16"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"57.8"	"57.6"	"62.5"	"77.0"	"49.7"	"58.0"	"81.3"	"111.1"	"128.7"	"326.4"	"517.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P61077"	"Ubiquitin-conjugating enzyme E2 D3 OS=Homo sapiens OX=9606 GN=UBE2D3 PE=1 SV=1"	""	""	"16"	"1"	"1"	"1"	"147"	"16.7"	"7.80"	""	"4.97"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00179"	"7323"	"ENSG00000109332"	"UBE2D3"	"A6NJ93; A6NJB1; A6NM99; hsa:7323; P47986; P61077; Q6IB88; Q6NXS4; Q8N924"	"Proteasome degradation"	"Peroxisomal protein import; Antigen processing: Ubiquitination & Proteasome degradation; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; Neddylation; E3 ubiquitin ligases ubiquitinate target proteins; IKK complex recruitment mediated by RIP1; Signaling by BMP; Inactivation of CSF3 (G-CSF) signaling; TICAM1, RIP1-mediated IKK complex recruitment; Regulation of TNFR1 signaling; Negative regulators of DDX58/IFIH1 signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity"	"13"	"0"	"3.8"	"3.9"	"6.6"	"8.3"	"7.2"	"2.6"	"8.1"	"9.1"	"7.7"	"44.4"	"112.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5M775"	"Cytospin-B OS=Homo sapiens OX=9606 GN=SPECC1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"1068"	"118.5"	"6.70"	"656.80"	"4.97"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00307"	"92521"	"ENSG00000128487"	"SPECC1"	"B4DHH0; B7WNS8; hsa:92521; Q5IBP1; Q5IBP2; Q5IBP3; Q5IBP4; Q5M772; Q5M773; Q5M774; Q5M775; Q86XT8; Q8N4U4; Q8WU84; Q9HCQ3"	""	""	"0"	"0"	"43.7"	"48.0"	"45.0"	"51.7"	"47.8"	"48.4"	"55.5"	"63.9"	"63.2"	"119.1"	"141.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI98"	"INO80 complex subunit C OS=Homo sapiens OX=9606 GN=INO80C PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"192"	"20.6"	"10.02"	"587.58"	"4.95"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf08265"	"125476"	"ENSG00000153391"	"INO80C"	"B4DUI4; E9PCS7; hsa:125476; Q6PI98; Q86WR1; Q8N994"	""	"UCH proteinases; DNA Damage Recognition in GG-NER"	"2"	"0"	"4.8"	"11.2"	"13.9"	"11.7"	"6.8"	"7.7"	"15.3"	"20.5"	"38.7"	"112.4"	"115.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00170"	"AH receptor-interacting protein OS=Homo sapiens OX=9606 GN=AIP PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"330"	"37.6"	"6.29"	"428.35"	"4.95"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"82.5"	"73.5"	"75.3"	"84.5"	"69.6"	"82.3"	"122.4"	"129.1"	"147.6"	"243.6"	"289.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P78318"	"Immunoglobulin-binding protein 1 OS=Homo sapiens OX=9606 GN=IGBP1 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"339"	"39.2"	"5.38"	""	"4.95"	""	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04177"	"3476"	"ENSG00000089289"	"IGBP1"	"hsa:3476; P78318; Q8TAB2"	"16p11.2 proximal deletion syndrome"	""	"1"	"0"	"29.3"	"17.6"	"37.2"	"43.0"	"34.2"	"24.3"	"33.8"	"44.4"	"37.2"	"56.4"	"76.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92522"	"Histone H1.10 OS=Homo sapiens OX=9606 GN=H1-10 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"213"	"22.5"	"10.76"	"490.30"	"4.94"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"8971"	"ENSG00000184897"	"H1-10"	"hsa:8971; Q92522"	""	""	"0"	"0"	"34.4"	"37.8"	"52.0"	"46.2"	"35.3"	"38.4"	"43.6"	"45.2"	"55.7"	"91.3"	"119.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYJ1"	"Cytochrome c oxidase assembly factor 4 homolog, mitochondrial OS=Homo sapiens OX=9606 GN=COA4 PE=1 SV=2"	"0.000"	""	"20"	"1"	"2"	"1"	"87"	"10.1"	"6.04"	"454.52"	"4.94"	"1"	"1"	"cell organization and biogenesis"	"mitochondrion"	""	""	"51287"	"ENSG00000181924"	"COA4"	"B2RAA0; hsa:51287; Q69YU4; Q9NYJ1"	""	"Mitochondrial protein import"	"1"	"0"	"54.1"	"34.2"	"55.1"	"62.4"	"51.0"	"37.7"	"57.9"	"67.1"	"63.4"	"66.3"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53EL6"	"Programmed cell death protein 4 OS=Homo sapiens OX=9606 GN=PDCD4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"469"	"51.7"	"5.21"	"458.54"	"4.94"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf02847"	"27250"	"ENSG00000150593"	"PDCD4"	"B2RCV4; B5ME91; hsa:27250; O15501; Q53EL6; Q5VZS6; Q6PJI5; Q8TAR5; Q99834"	"Translation inhibitors in chronically activated PDGFRA cells; A network map of Macrophage-stimulating protein (MSP) signaling; Interferon type I signaling pathways"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation"	"4"	"0"	"15.0"	"14.6"	"12.8"	"23.7"	"14.3"	"11.8"	"25.1"	"39.9"	"56.8"	"336.4"	"563.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6P5R6"	"60S ribosomal protein L22-like 1 OS=Homo sapiens OX=9606 GN=RPL22L1 PE=1 SV=2"	""	""	"20"	"1"	"1"	"1"	"122"	"14.6"	"9.38"	""	"4.93"	""	"1"	"protein metabolism;other metabolic processes"	"translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01776"	"200916"	"ENSG00000163584"	"RPL22L1"	"hsa:200916; Q32Q77; Q6P5R6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"13"	"0"	"24.0"	"19.3"	"21.2"	"36.5"	"22.3"	"26.3"	"35.7"	"40.7"	"53.1"	"89.3"	"91.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00139"	"Kinesin-like protein KIF2A OS=Homo sapiens OX=9606 GN=KIF2A PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"706"	"79.9"	"6.68"	"385.85"	"4.93"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225"	"3796"	"ENSG00000068796"	"KIF2A"	"A5YM42; A5YM54; B4DY54; D3DW97; E9PB70; hsa:3796; O00139; Q7Z5I3; Q8N5Q7"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Kinesins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"66.4"	"46.6"	"75.6"	"85.6"	"51.5"	"53.5"	"102.6"	"101.6"	"122.5"	"204.0"	"228.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0W8"	"Protein SMG9 OS=Homo sapiens OX=9606 GN=SMG9 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"520"	"57.6"	"7.01"	"561.00"	"4.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf10220"	"56006"	"ENSG00000105771"	"SMG9"	"hsa:56006; O60429; Q9H0W8; Q9H9A9"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	"27.0"	"26.3"	"13.3"	"20.5"	"18.5"	"13.8"	"21.0"	"35.0"	"31.6"	"58.1"	"69.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15758"	"Neutral amino acid transporter B(0) OS=Homo sapiens OX=9606 GN=SLC1A5 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"541"	"56.6"	"5.48"	"519.01"	"4.93"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00375"	"6510"	"ENSG00000105281"	"SLC1A5"	"A8K9H5; B4DR77; B4DWS4; B7ZB81; D0EYG6; E9PC01; hsa:6510; O95720; Q15758; Q96RL9; Q9BWQ3; Q9UNP2"	"TYROBP causal network in microglia; mRNA, protein, and metabolite inducation pathway by cyclosporin A; Metabolic reprogramming in colon cancer; Ferroptosis; Amino acid metabolism in triple-negative breast cancer cells"	"RHOH GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Amino acid transport across the plasma membrane"	"11"	"0"	"45.9"	"42.4"	"58.9"	"55.8"	"41.8"	"49.5"	"68.4"	"61.7"	"95.2"	"159.7"	"242.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4P3"	"Transducin beta-like protein 2 OS=Homo sapiens OX=9606 GN=TBL2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"447"	"49.8"	"9.44"	"569.59"	"4.91"	"1"	"1"	"stress response;signal transduction"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00400"	"26608"	"ENSG00000106638"	"TBL2"	"hsa:26608; Q9UQE2; Q9Y4P3"	"7q11.23 copy number variation syndrome"	""	"1"	"0"	"20.1"	"11.2"	"22.3"	"30.3"	"28.5"	"15.3"	"35.4"	"33.9"	"44.5"	"81.1"	"161.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99417"	"c-Myc-binding protein OS=Homo sapiens OX=9606 GN=MYCBP PE=1 SV=3"	"0.000"	""	"19"	"1"	"2"	"1"	"103"	"12.0"	"5.91"	"490.11"	"4.91"	"1"	"1"	"other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	""	"26292"	"ENSG00000214114"	"MYCBP"	"B2R4N0; hsa:26292; Q5TA64; Q96HE2; Q99417"	"Pathways affected in adenoid cystic carcinoma"	""	"1"	"0"	"5.2"	"11.5"	"13.2"	"21.0"	"14.2"	"8.4"	"29.6"	"32.1"	"57.6"	"144.8"	"242.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BV81"	"ER membrane protein complex subunit 6 OS=Homo sapiens OX=9606 GN=EMC6 PE=1 SV=1"	"0.000"	""	"12"	"1"	"2"	"1"	"110"	"12.0"	"10.07"	"481.72"	"4.90"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"other membranes;ER/Golgi"	""	"Pf07019"	"83460"	"ENSG00000127774"	"EMC6"	"hsa:83460; Q9BV81"	""	""	"0"	"0"	"8.7"	"6.3"	"9.1"	"11.6"	"8.9"	"4.0"	"8.9"	"14.4"	"25.3"	"47.6"	"69.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q92974"	"Rho guanine nucleotide exchange factor 2 OS=Homo sapiens OX=9606 GN=ARHGEF2 PE=1 SV=4"	""	""	"3"	"1"	"1"	"1"	"986"	"111.5"	"7.27"	""	"4.89"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00621, Pf17838"	"9181"	"ENSG00000116584"	"ARHGEF2"	"D3DVA6; hsa:9181; O75142; Q15079; Q5VY92; Q8TDA3; Q8WUG4; Q92974; Q9H023"	"Pathogenic Escherichia coli infection"	"G alpha (12/13) signalling events; RHOA GTPase cycle; NRAGE signals death through JNK; RHOB GTPase cycle"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4W6"	"AFG3-like protein 2 OS=Homo sapiens OX=9606 GN=AFG3L2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"5"	"1"	"797"	"88.5"	"8.66"	"835.50"	"4.88"	"2"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00004, Pf01434, Pf06480, Pf17862"	"10939"	"ENSG00000141385"	"AFG3L2"	"hsa:10939; Q6P1L0; Q9Y4W6"	"Ciliary landscape; 10q22q23 copy number variation"	"Processing of SMDT1"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C36"	"Pyrroline-5-carboxylate reductase 2 OS=Homo sapiens OX=9606 GN=PYCR2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"320"	"33.6"	"7.77"	"363.58"	"4.87"	"1"	"1"	"other metabolic processes;stress response"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"29920"	"ENSG00000143811"	"PYCR2"	"A8K798; hsa:29920; Q7Z515; Q96C36; Q9Y5J4"	"Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"2"	"0"	"46.5"	"42.0"	"57.6"	"71.2"	"50.8"	"55.4"	"100.4"	"124.0"	"128.6"	"397.6"	"547.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y657"	"Spindlin-1 OS=Homo sapiens OX=9606 GN=SPIN1 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"262"	"29.6"	"6.96"	"458.34"	"4.87"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf02513"	"10927"	"ENSG00000106723"	"SPIN1"	"A8K0X6; B3KRQ4; hsa:10927; Q7KZJ8; Q9GZT2; Q9H0N7; Q9Y657"	""	""	"0"	"0"	"38.1"	"38.3"	"40.4"	"47.5"	"34.7"	"35.1"	"64.1"	"80.4"	"95.9"	"202.8"	"212.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P57772"	"Selenocysteine-specific elongation factor OS=Homo sapiens OX=9606 GN=EEFSEC PE=1 SV=4"	"0.000"	""	"3"	"2"	"4"	"2"	"596"	"65.3"	"8.35"	"544.07"	"4.86"	"2"	"2"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"60678"	"ENSG00000132394; ENSG00000284869"	"EEFSEC"	"hsa:60678; P57772; Q96HZ6"	""	"Selenocysteine synthesis"	"1"	"0"	"278.3"	"190.5"	"325.7"	"314.6"	"242.7"	"312.2"	"760.6"	"814.6"	"862.7"	"719.8"	"803.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75489"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS3 PE=1 SV=1"	"0.000"	""	"11"	"2"	"3"	"2"	"264"	"30.2"	"7.50"	"1040.77"	"4.86"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00329"	"4722"	"ENSG00000213619; ENSG00000285387"	"NDUFS3"	"B2R9J1; B4DFM8; hsa:4722; O75489; Q9UNQ8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"RHOG GTPase cycle; Complex I biogenesis"	"6"	"0"	"83.6"	"72.4"	"74.9"	"107.0"	"66.6"	"75.5"	"140.7"	"152.3"	"247.5"	"659.4"	"833.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32121"	"Beta-arrestin-2 OS=Homo sapiens OX=9606 GN=ARRB2 PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"409"	"46.1"	"7.69"	"343.49"	"4.85"	"1"	"2"	"cell-cell signaling;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00339, Pf02752"	"409"	"ENSG00000141480"	"ARRB2"	"B4DLW0; B5B0C0; B7WPL3; D3DTK2; H0Y688; hsa:409; P32121; Q0Z8D3; Q2PP19; Q6ICT3; Q8N7Y2; Q9UEQ6"	"Corticotropin-releasing hormone signaling pathway; Complement system; Myometrial relaxation and contraction pathways; Wnt signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Ub-specific processing proteases; Activated NOTCH1 Transmits Signal to the Nucleus; Cargo recognition for clathrin-mediated endocytosis; Activation of SMO; G alpha (s) signalling events; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); WNT5A-dependent internalization of FZD4; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"27"	"0"	"118.7"	"125.4"	"160.8"	"191.9"	"125.9"	"190.5"	"499.6"	"613.1"	"439.7"	"506.3"	"692.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14649"	"Myosin light chain 6B OS=Homo sapiens OX=9606 GN=MYL6B PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"208"	"22.8"	"5.73"	"478.93"	"4.84"	"1"	"1"	"other biological processes"	"cytosol;cytoskeleton"	"cytoskeletal activity;other molecular function"	""	"140465"	"ENSG00000196465"	"MYL6B"	"hsa:140465; P14649"	"Ciliary landscape"	"Smooth Muscle Contraction"	"2"	"0"	"15.5"	"15.4"	"27.1"	"25.9"	"15.1"	"13.9"	"32.4"	"29.3"	"40.1"	"105.4"	"155.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WG5"	"Myotubularin-related protein 13 OS=Homo sapiens OX=9606 GN=SBF2 PE=1 SV=1"	"0.000"	""	"1"	"2"	"3"	"2"	"1849"	"208.3"	"7.06"	"862.38"	"4.83"	"2"	"1"	"other metabolic processes;developmental processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf02141, Pf02893, Pf03456, Pf06602, Pf12335"	"81846"	"ENSG00000133812"	"SBF2"	"hsa:81846; Q3MJF0; Q68DQ3; Q6P459; Q6PJD1; Q7Z325; Q7Z621; Q86VE2; Q86WG5; Q96FE2; Q9C097"	"Intracellular trafficking proteins involved in CMT neuropathy"	"RAB GEFs exchange GTP for GDP on RABs; Synthesis of PIPs at the plasma membrane"	"3"	"0"	"65.6"	"46.4"	"81.3"	"96.7"	"81.5"	"110.6"	"259.0"	"277.3"	"375.0"	"601.3"	"708.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52926"	"High mobility group protein HMGI-C OS=Homo sapiens OX=9606 GN=HMGA2 PE=1 SV=1"	"0.000"	""	"38"	"2"	"2"	"2"	"109"	"11.8"	"10.62"	"385.49"	"4.83"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02178"	"8091"	"ENSG00000149948"	"HMGA2"	"E7EP85; E7EWA2; hsa:8091; P52926; Q1M182; Q1M185; Q1M186; Q1M187; Q1M188"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Orexin receptor pathway"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"6"	"0"	"51.2"	"60.8"	"51.9"	"51.6"	"54.9"	"45.3"	"69.2"	"74.3"	"79.3"	"160.8"	"206.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2M2I8"	"AP2-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=AAK1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"961"	"103.8"	"6.60"	"379.11"	"4.82"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00069"	"22848"	"ENSG00000115977"	"AAK1"	"hsa:22848; Q2M2I8; Q4ZFZ3; Q53RX6; Q9UPV4"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	"18.5"	"24.3"	"19.9"	"20.6"	"15.2"	"12.1"	"25.6"	"27.0"	"27.8"	"47.2"	"61.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y371"	"Endophilin-B1 OS=Homo sapiens OX=9606 GN=SH3GLB1 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"365"	"40.8"	"6.04"	""	"4.81"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03114, Pf14604"	"51100"	"ENSG00000097033"	"SH3GLB1"	"B4E182; hsa:51100; Q5H8U5; Q9H3Z0; Q9NR47; Q9NYA9; Q9Y371"	"Nanoparticle triggered autophagic cell death"	""	"1"	"0"	"25.5"	"28.8"	"24.4"	"58.0"	"32.1"	"25.9"	"52.0"	"62.7"	"100.8"	"309.9"	"390.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75794"	"Cell division cycle protein 123 homolog OS=Homo sapiens OX=9606 GN=CDC123 PE=1 SV=1"	"0.000"	""	"2"	"1"	"4"	"1"	"336"	"39.1"	"4.81"	"503.88"	"4.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	""	"Pf07065"	"8872"	"ENSG00000151465"	"CDC123"	"A8JZZ7; hsa:8872; O75794; Q14107; Q5T0L4; Q5T0L5; Q5T0L7; Q5T0L8; Q5T0L9"	""	""	"0"	"0"	"62.7"	"62.4"	"82.9"	"95.0"	"56.6"	"51.1"	"738.2"	"817.8"	"1897.7"	"2778.9"	"1695.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H814"	"Phosphorylated adapter RNA export protein OS=Homo sapiens OX=9606 GN=PHAX PE=1 SV=1"	"0.000"	""	"5"	"2"	"4"	"2"	"394"	"44.4"	"5.40"	"553.53"	"4.81"	"2"	"2"	"transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10258"	"51808"	"ENSG00000164902"	"PHAX"	"hsa:51808; Q9H814; Q9H8W1"	""	"RNA polymerase II transcribes snRNA genes; snRNP Assembly"	"2"	"0"	"53.9"	"50.9"	"54.7"	"71.6"	"33.2"	"44.4"	"58.2"	"70.9"	"62.3"	"137.1"	"219.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43639"	"Cytoplasmic protein NCK2 OS=Homo sapiens OX=9606 GN=NCK2 PE=1 SV=2"	"0.001"	""	"8"	"2"	"2"	"1"	"380"	"42.9"	"6.95"	"237.88"	"4.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf14604"	"8440"	"ENSG00000071051"	"NCK2"	"D3DVK1; hsa:8440; O43639; Q9BWN9; Q9UIC3"	"Pathogenic Escherichia coli infection; Brain-derived neurotrophic factor (BDNF) signaling pathway; EGF/EGFR signaling pathway; Genes controlling nephrogenesis; ErbB signaling pathway"	"RHOV GTPase cycle; RHOU GTPase cycle; Nephrin family interactions; Downstream signal transduction; VEGFA-VEGFR2 Pathway; Ephrin signaling; Activation of RAC1; Regulation of cortical dendrite branching"	"13"	"0"	"7.5"	"10.5"	"12.1"	"17.6"	"14.6"	"11.0"	"15.8"	"21.0"	"32.3"	"111.5"	"180.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJX2"	"Cell division cycle protein 23 homolog OS=Homo sapiens OX=9606 GN=CDC23 PE=1 SV=3"	"0.000"	""	"6"	"3"	"3"	"3"	"597"	"68.8"	"7.02"	"269.61"	"4.79"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf04049"	"8697"	"ENSG00000094880"	"CDC23"	"A8K6E5; B4E3A2; B7WP05; D3DQB7; hsa:8697; O75433; Q53FN2; Q9BS73; Q9UJX2"	"Cell cycle"	"Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	"121.4"	"102.4"	"163.6"	"199.8"	"132.7"	"111.0"	"244.9"	"250.2"	"323.8"	"697.0"	"918.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15061"	"WD repeat-containing protein 43 OS=Homo sapiens OX=9606 GN=WDR43 PE=1 SV=3"	"0.000"	""	"5"	"3"	"5"	"3"	"677"	"74.8"	"5.57"	"1205.13"	"4.78"	"3"	"2"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf04003"	"23160"	"ENSG00000163811"	"WDR43"	"hsa:23160; Q15061; Q15395; Q92577"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"419.8"	"378.8"	"424.6"	"468.2"	"340.1"	"338.6"	"678.3"	"735.0"	"975.4"	"1816.6"	"2193.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95825"	"Quinone oxidoreductase-like protein 1 OS=Homo sapiens OX=9606 GN=CRYZL1 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"349"	"38.7"	"5.78"	"658.13"	"4.77"	"1"	"1"	"other metabolic processes"	""	"other molecular function"	""	"9946"	"ENSG00000205758"	"CRYZL1"	"B2RDX1; B3KQ77; hsa:9946; O95825; Q96DY0; Q9NVY7"	""	""	"0"	"0"	"15.2"	"14.3"	"15.0"	"22.6"	"14.0"	"16.0"	"47.6"	"48.6"	"96.1"	"283.0"	"354.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95777"	"U6 snRNA-associated Sm-like protein LSm8 OS=Homo sapiens OX=9606 GN=LSM8 PE=1 SV=3"	"0.000"	""	"20"	"1"	"2"	"1"	"96"	"10.4"	"4.48"	"393.71"	"4.75"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01423"	"51691"	"ENSG00000128534"	"LSM8"	"hsa:51691; O95777"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"52.2"	"18.3"	"72.7"	"100.1"	"51.6"	"50.9"	"75.6"	"75.3"	"85.7"	"164.9"	"261.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IY1"	"Kinetochore-associated protein NSL1 homolog OS=Homo sapiens OX=9606 GN=NSL1 PE=1 SV=3"	"0.000"	""	"9"	"2"	"3"	"2"	"281"	"32.1"	"6.79"	"720.26"	"4.75"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf08641"	"25936"	"ENSG00000117697"	"NSL1"	"E7ETD5; hsa:25936; Q5SY75; Q96IY1; Q9H2M5; Q9NRN8; Q9Y415"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"44.9"	"33.5"	"38.8"	"68.9"	"40.5"	"51.2"	"84.0"	"98.9"	"162.9"	"673.9"	"1181.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28066"	"Proteasome subunit alpha type-5 OS=Homo sapiens OX=9606 GN=PSMA5 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"241"	"26.4"	"4.79"	"533.80"	"4.74"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227, Pf10584"	"5686"	"ENSG00000143106"	"PSMA5"	"B2R8F6; B4E2V4; hsa:5686; P28066; Q3T1C1; Q6IBF7"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Neutrophil degranulation; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"31.3"	"33.4"	"41.3"	"54.3"	"28.7"	"34.8"	"47.7"	"49.5"	"54.5"	"170.0"	"517.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WV22"	"Non-structural maintenance of chromosomes element 1 homolog OS=Homo sapiens OX=9606 GN=NSMCE1 PE=1 SV=5"	"0.000"	""	"7"	"1"	"2"	"1"	"266"	"30.8"	"7.47"	"600.22"	"4.74"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf07574, Pf08746"	"197370"	"ENSG00000169189"	"NSMCE1"	"D3DWF6; hsa:197370; Q8WV22; Q9P045; Q9P049"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"9.4"	"8.3"	"9.5"	"12.3"	"7.7"	"9.1"	"17.4"	"17.8"	"14.7"	"28.7"	"31.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10155"	"60 kDa SS-A/Ro ribonucleoprotein OS=Homo sapiens OX=9606 GN=RO60 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"538"	"60.6"	"8.03"	"560.56"	"4.74"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05731"	"6738"	"ENSG00000116747"	"RO60"	"B2RBB9; hsa:6738; P10155; Q5LJ98; Q5LJ99; Q5LJA0; Q86WL3; Q86WL4; Q92787; Q9H1W6"	""	""	"0"	"0"	"83.2"	"80.2"	"98.5"	"123.6"	"85.2"	"70.6"	"128.4"	"135.7"	"162.1"	"281.7"	"406.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVS4"	"Serine/threonine-protein kinase RIO2 OS=Homo sapiens OX=9606 GN=RIOK2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"552"	"63.2"	"5.94"	"333.61"	"4.74"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf01163, Pf09202"	"55781"	"ENSG00000058729"	"RIOK2"	"D6RDI3; hsa:55781; Q9BVS4; Q9NUT0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"6.8"	"11.3"	"3.8"	"7.8"	"8.8"	"7.1"	"11.3"	"14.8"	"18.4"	"32.7"	"38.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N122"	"Regulatory-associated protein of mTOR OS=Homo sapiens OX=9606 GN=RPTOR PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1335"	"148.9"	"6.89"	"468.58"	"4.73"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00400, Pf02985, Pf14538"	"57521"	"ENSG00000141564"	"RPTOR"	"B2RN36; C6KEF2; F5H7J5; hsa:57521; Q8N122; Q8N4V9; Q8TB32; Q9P2P3"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Clear cell renal cell carcinoma pathways; PI3K-Akt signaling pathway; Thermogenesis; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; CAMKK2 pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; JAK-STAT signaling in the regulation of Beta-cells; Interferon type I signaling pathways"	"Regulation of PTEN gene transcription; TP53 Regulates Metabolic Genes; Amino acids regulate mTORC1; mTORC1-mediated signalling; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK; HSF1-dependent transactivation"	"33"	"0"	"22.3"	"20.7"	"26.0"	"30.6"	"24.2"	"10.5"	"40.1"	"43.1"	"61.0"	"171.8"	"224.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q0JRZ9"	"F-BAR domain only protein 2 OS=Homo sapiens OX=9606 GN=FCHO2 PE=1 SV=2"	"0.001"	""	"2"	"2"	"3"	"1"	"810"	"88.9"	"6.86"	"252.44"	"4.72"	"1"	"2"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00611, Pf10291"	"115548"	"ENSG00000157107"	"FCHO2"	"A8K6W7; B2RNQ9; B4DHK0; E9PG79; hsa:115548; Q0JRZ9; Q0JTJ3; Q96CF5"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VYK3"	"Proteasome adapter and scaffold protein ECM29 OS=Homo sapiens OX=9606 GN=ECPAS PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1845"	"204.2"	"7.12"	"540.03"	"4.71"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response"	"cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13001"	""	"ENSG00000136813"	"ECPAS"	"O15074; Q5VYK3; Q8WU82"	""	""	"0"	"0"	"21.7"	"18.4"	"20.2"	"37.7"	"18.2"	"17.5"	"33.2"	"51.9"	"90.2"	"254.6"	"357.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13889"	"General transcription factor IIH subunit 3 OS=Homo sapiens OX=9606 GN=GTF2H3 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"308"	"34.4"	"7.02"	"443.50"	"4.71"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf03850"	"2967"	"ENSG00000111358"	"GTF2H3"	"B2R819; B4DNZ6; hsa:2967; Q13889; Q7L0G0; Q96AT7"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"RNA Polymerase II Pre-transcription Events; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"33"	"0"	"24.2"	"18.0"	"26.4"	"33.9"	"21.2"	"26.4"	"80.8"	"93.8"	"115.5"	"167.2"	"171.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96SK2"	"Transmembrane protein 209 OS=Homo sapiens OX=9606 GN=TMEM209 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"561"	"62.9"	"8.63"	""	"4.71"	""	"1"	""	"other membranes"	""	"Pf09786"	"84928"	"ENSG00000146842"	"TMEM209"	"A4D1L1; hsa:84928; Q49A50; Q6PF00; Q8NCH3; Q96SK2; Q96SL6"	""	""	"0"	"0"	"11.9"	"10.4"	"13.1"	"16.4"	"12.3"	"8.3"	"16.7"	"24.4"	"25.5"	"57.8"	"75.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2K1"	"Coiled-coil and C2 domain-containing protein 2A OS=Homo sapiens OX=9606 GN=CC2D2A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1620"	"186.1"	"6.74"	"518.40"	"4.71"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	""	"Pf00168, Pf15625, Pf17661"	"57545"	"ENSG00000048342"	"CC2D2A"	"A6ND97; B3FW08; D6RB72; E7EP21; E9PEV5; hsa:57545; Q3SYP3; Q9H8A7; Q9P2K1"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies"	"Anchoring of the basal body to the plasma membrane"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15008"	"26S proteasome non-ATPase regulatory subunit 6 OS=Homo sapiens OX=9606 GN=PSMD6 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"389"	"45.5"	"5.62"	"589.30"	"4.70"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf01399, Pf10602"	"9861"	"ENSG00000163636"	"PSMD6"	"A8K2E0; E9PHI9; hsa:9861; Q15008; Q6UV22"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Alzheimer's disease"	"Separation of Sister Chromatids; Neutrophil degranulation; AUF1 (hnRNP D0) binds and destabilizes mRNA; Regulation of expression of SLITs and ROBOs; ABC-family proteins mediated transport; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"58.5"	"54.0"	"70.5"	"93.4"	"57.8"	"58.2"	"105.1"	"113.1"	"131.4"	"702.3"	"1695.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75306"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"463"	"52.5"	"7.55"	"397.27"	"4.70"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;mitochondrion;nucleus"	"transporter activity;other molecular function"	"Pf00346"	"4720"	"ENSG00000158864"	"NDUFS2"	"D3DVG7; hsa:4720; J3KPM7; O75306; Q5VTW0; Q969P3; Q9UEV3"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"23.3"	"32.0"	"19.1"	"35.8"	"19.1"	"16.2"	"27.4"	"40.8"	"47.1"	"117.0"	"175.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P60953"	"Cell division control protein 42 homolog OS=Homo sapiens OX=9606 GN=CDC42 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"191"	"21.2"	"6.55"	"490.66"	"4.69"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00071"	"998"	"ENSG00000070831"	"CDC42"	"hsa:998; P21181; P25763; P60953; Q7L8R5; Q9UDI2"	"Androgen receptor signaling pathway; Target of rapamycin signaling; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Leptin signaling pathway; Microtubule cytoskeleton regulation; Metastatic brain tumor; Pathogenic Escherichia coli infection; RalA downstream regulated genes; B cell receptor signaling pathway; AGE/RAGE pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Focal adhesion; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; p38 MAPK signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway; Nonalcoholic fatty liver disease; Hippo signaling regulation pathways; 22q11.2 copy number variation syndrome; Gastrin signaling pathway; Regulation of actin cytoskeleton; G13 signaling pathway; Genetic causes of porto-sinusoidal vascular disease; 13q12.12 copy number variation; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"RHO GTPases Activate Formins; MAPK6/MAPK4 signaling; RHO GTPases activate IQGAPs; RAC1 GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; EPHB-mediated forward signaling; DCC mediated attractive signaling; GPVI-mediated activation cascade; Myogenesis; Factors involved in megakaryocyte development and platelet production; G beta:gamma signalling through CDC42; EGFR downregulation; RHO GTPases activate PAKs; Inactivation of CDC42 and RAC1; CD28 dependent Vav1 pathway; RHO GTPases activate KTN1"	"61"	"0"	"117.7"	"109.1"	"124.9"	"139.6"	"107.8"	"133.1"	"171.7"	"167.5"	"224.8"	"479.6"	"550.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00505"	"Aspartate aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=GOT2 PE=1 SV=3"	"0.000"	""	"6"	"2"	"3"	"2"	"430"	"47.5"	"9.01"	"978.14"	"4.69"	"2"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf00155"	"2806"	"ENSG00000125166"	"GOT2"	"B4DJA6; E7ERW2; hsa:2806; P00505; Q53FL3; Q9BWA3"	"Alanine and aspartate metabolism; Amino acid metabolism; Metabolic reprogramming in colon cancer; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glyoxylate metabolism and glycine degradation; Gluconeogenesis; Aspartate and asparagine metabolism; Glutamate and glutamine metabolism; Degradation of cysteine and homocysteine"	"11"	"0"	"209.9"	"172.2"	"270.4"	"226.1"	"174.8"	"239.7"	"262.7"	"257.6"	"346.3"	"501.0"	"698.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P015"	"39S ribosomal protein L15, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL15 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"296"	"33.4"	"10.01"	"517.19"	"4.67"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00828"	"29088"	"ENSG00000137547"	"MRPL15"	"hsa:29088; Q96Q54; Q9H0Y1; Q9P015"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"139.9"	"138.1"	"160.4"	"181.9"	"135.6"	"145.8"	"203.9"	"198.2"	"222.5"	"512.9"	"980.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YN4"	"Protein virilizer homolog OS=Homo sapiens OX=9606 GN=VIRMA PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1812"	"201.9"	"5.01"	"582.04"	"4.67"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf15912"	"25962"	"ENSG00000164944"	"VIRMA"	"hsa:25962; Q2M1N0; Q69YN4; Q6AHX9; Q6NT78; Q7Z6C7; Q8IXH4; Q9BTH4; Q9H9C9; Q9NWR3; Q9P2B8; Q9UFW1"	""	""	"0"	"0"	"9.3"	"7.1"	"11.7"	"12.6"	"12.5"	"9.6"	"11.0"	"16.4"	"19.9"	"69.7"	"173.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01970"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 OS=Homo sapiens OX=9606 GN=PLCB3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1234"	"138.7"	"5.90"	"528.82"	"4.67"	"1"	"1"	"other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf08703, Pf09279, Pf17787"	"5331"	"ENSG00000149782"	"PLCB3"	"A5PKZ6; G5E960; hsa:5331; Q01970; Q8N1A4"	"Alzheimer's disease and miRNA effects; S1P receptor signal transduction; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; GPR40 pathway; MAPK cascade; Wnt signaling; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Hippo signaling regulation pathways; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Neuroinflammation and glutamatergic signaling; Alzheimer's disease; Calcium regulation in cardiac cells"	"G alpha (q) signalling events; Ca2+ pathway; G beta:gamma signalling through PLC beta; Presynaptic function of Kainate receptors; Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion; Synthesis of IP3 and IP4 in the cytosol; PLC beta mediated events; Acetylcholine regulates insulin secretion"	"26"	"0"	"22.1"	"17.6"	"32.2"	"38.4"	"19.4"	"25.2"	"38.3"	"37.8"	"50.3"	"76.3"	"103.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUQ7"	"Cactin OS=Homo sapiens OX=9606 GN=CACTIN PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"758"	"88.6"	"9.14"	"621.28"	"4.67"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf09732, Pf10312"	"58509"	"ENSG00000105298"	"CACTIN"	"A6NNA9; A9UL12; hsa:58509; O75229; Q7LE08; Q8WUQ7; Q9BTA6; Q9Y5A4"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"12.9"	"8.4"	"14.3"	"17.8"	"16.2"	"11.4"	"18.9"	"17.5"	"29.2"	"56.3"	"75.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXK1"	"Krueppel-like factor 16 OS=Homo sapiens OX=9606 GN=KLF16 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"252"	"25.4"	"9.88"	"636.65"	"4.67"	"1"	"1"	"signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"83855"	"ENSG00000129911"	"KLF16"	"hsa:83855; Q9BXK1"	""	""	"0"	"0"	"8.1"	"14.2"	"10.9"	"10.2"	"8.2"	"8.9"	"11.6"	"16.6"	"12.6"	"31.5"	"34.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93034"	"Cullin-5 OS=Homo sapiens OX=9606 GN=CUL5 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"780"	"90.9"	"7.94"	"402.67"	"4.67"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;transport;signal transduction"	"cytosol;nucleus;other cell component"	"transporter activity;other molecular function"	"Pf00888, Pf10557"	"8065"	"ENSG00000166266"	"CUL5"	"A8K960; hsa:8065; O14766; Q93034; Q9BZC6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; Dual hijack model of Vif in HIV infection; Modulators of TCR signaling and T cell activation; 10q11.21q11.23 copy number variation syndrome"	"Neddylation; Antigen processing: Ubiquitination & Proteasome degradation; Vif-mediated degradation of APOBEC3G; Downregulation of ERBB2 signaling; Inactivation of CSF3 (G-CSF) signaling"	"9"	"0"	"9.4"	"5.6"	"12.9"	"16.3"	"10.1"	"9.8"	"34.7"	"37.3"	"71.1"	"246.2"	"392.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13084"	"39S ribosomal protein L28, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL28 PE=1 SV=4"	"0.000"	""	"7"	"2"	"3"	"2"	"256"	"30.1"	"8.29"	"733.69"	"4.65"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00830"	"10573"	"ENSG00000086504"	"MRPL28"	"B2RCM4; D3DU46; hsa:10573; Q13084; Q4TT39; Q96S26; Q9BQD8; Q9BR04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"310.0"	"324.7"	"294.4"	"356.4"	"245.2"	"252.6"	"428.9"	"441.3"	"460.2"	"1039.2"	"1774.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKJ3"	"G patch domain-containing protein 8 OS=Homo sapiens OX=9606 GN=GPATCH8 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1502"	"164.1"	"8.66"	"447.04"	"4.65"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01585, Pf12171"	"23131"	"ENSG00000186566"	"GPATCH8"	"B9EGP9; hsa:23131; O60300; Q8TB99; Q9UKJ3"	""	""	"0"	"0"	"77.0"	"70.6"	"101.6"	"116.1"	"79.0"	"76.0"	"111.1"	"124.0"	"120.0"	"252.1"	"340.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVH1"	"DnaJ homolog subfamily C member 11 OS=Homo sapiens OX=9606 GN=DNAJC11 PE=1 SV=2"	"0.000"	""	"2"	"1"	"3"	"1"	"559"	"63.2"	"8.40"	"827.02"	"4.65"	"1"	"1"	"cell organization and biogenesis"	"other membranes;mitochondrion;nucleus"	""	"Pf00226, Pf11875"	"55735"	"ENSG00000007923"	"DNAJC11"	"hsa:55735; Q4VWF5; Q5VZN0; Q6PK20; Q6PK70; Q8NDM2; Q96CL7; Q9NVH1"	""	"Cristae formation"	"1"	"0"	"4.2"	"3.4"	"0.0"	"4.3"	"0.0"	"0.0"	"4.9"	"9.6"	"14.6"	"43.3"	"86.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23258"	"Tubulin gamma-1 chain OS=Homo sapiens OX=9606 GN=TUBG1 PE=1 SV=2"	"0.000"	""	"8"	"3"	"6"	"3"	"451"	"51.1"	"6.14"	"1614.17"	"4.65"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00091, Pf03953"	"7283"	"ENSG00000131462"	"TUBG1"	"hsa:7283; P23258; Q53X79; Q9BW59"	"Alstrom syndrome"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"8"	"0"	"287.6"	"250.5"	"301.6"	"393.7"	"250.3"	"287.7"	"724.6"	"813.1"	"1340.0"	"1712.7"	"1595.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UP3"	"Zinc finger homeobox protein 4 OS=Homo sapiens OX=9606 GN=ZFHX4 PE=1 SV=1"	"0.000"	""	"0"	"1"	"2"	"1"	"3567"	"393.5"	"6.37"	"512.67"	"4.65"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf00096, Pf12874"	"79776"	"ENSG00000091656"	"ZFHX4"	"G3V138; hsa:79776; Q18PS0; Q6ZN20; Q86UP3"	"Mesodermal commitment pathway; Ectoderm differentiation; Ectoderm differentiation"	""	"3"	"0"	"50.6"	"40.3"	"65.4"	"64.0"	"54.5"	"57.9"	"71.3"	"69.7"	"77.6"	"139.3"	"205.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99959"	"Plakophilin-2 OS=Homo sapiens OX=9606 GN=PKP2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"881"	"97.4"	"9.33"	"312.64"	"4.64"	"1"	"2"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00514"	"5318"	"ENSG00000057294"	"PKP2"	"A0AV37; B8QFA1; B8QGS6; B8QGS7; D3DUW9; hsa:5318; Q4VC01; Q99959; Q99960"	"Arrhythmogenic right ventricular cardiomyopathy; Epithelial to mesenchymal transition in colorectal cancer"	"Formation of the cornified envelope"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZX2"	"Uridine-cytidine kinase 2 OS=Homo sapiens OX=9606 GN=UCK2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"261"	"29.3"	"6.70"	"544.83"	"4.64"	"1"	"1"	"other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00485"	"7371"	"ENSG00000143179"	"UCK2"	"hsa:7371; Q5VV91; Q7KZV3; Q92528; Q96KG5; Q9BU42; Q9BZX2"	"Fluoropyrimidine activity; Pyrimidine metabolism"	"Pyrimidine salvage"	"3"	"0"	"15.3"	"13.1"	"13.1"	"16.3"	"14.4"	"19.0"	"25.6"	"25.6"	"36.6"	"89.7"	"133.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12814"	"Alpha-actinin-1 OS=Homo sapiens OX=9606 GN=ACTN1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"892"	"103.0"	"5.41"	"692.76"	"4.63"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00307, Pf00435, Pf08726"	"87"	"ENSG00000072110"	"ACTN1"	"B3V8S3; B4DHH3; B7TY16; hsa:87; P12814; Q1HE25; Q9BTN1"	"Arrhythmogenic right ventricular cardiomyopathy; Focal adhesion; Ebola virus infection in host; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Regulation of actin cytoskeleton"	"Platelet degranulation ; RHOD GTPase cycle; RHOF GTPase cycle; Nephrin family interactions; Syndecan interactions; RHOBTB2 GTPase cycle; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"12"	"0"	"41.5"	"38.6"	"66.5"	"82.6"	"48.6"	"49.2"	"70.2"	"80.2"	"101.5"	"214.1"	"262.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02413"	"Desmoglein-1 OS=Homo sapiens OX=9606 GN=DSG1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1049"	"113.7"	"5.03"	"654.99"	"4.63"	"1"	"1"	"cell adhesion;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00028, Pf01049"	"1828"	"ENSG00000134760"	"DSG1"	"B7Z845; hsa:1828; Q02413"	""	"Neutrophil degranulation; Formation of the cornified envelope; RND2 GTPase cycle; RND3 GTPase cycle; Apoptotic cleavage of cell adhesion  proteins"	"6"	"0"	"14.7"	"31.9"	"180.3"	"15.2"	"6.2"	"14.1"	"34.6"	"29.6"	"35.9"	"69.0"	"94.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61026"	"Ras-related protein Rab-10 OS=Homo sapiens OX=9606 GN=RAB10 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"200"	"22.5"	"8.38"	"569.89"	"4.63"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00071"	"10890"	"ENSG00000084733"	"RAB10"	"D6W538; hsa:10890; O88386; P61026; Q6IA52; Q9D7X6; Q9H0T3"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"RAB GEFs exchange GTP for GDP on RABs; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Neutrophil degranulation; RAB geranylgeranylation"	"5"	"0"	"28.3"	"35.7"	"49.5"	"60.3"	"30.6"	"37.5"	"63.6"	"60.1"	"91.7"	"280.1"	"432.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28074"	"Proteasome subunit beta type-5 OS=Homo sapiens OX=9606 GN=PSMB5 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"263"	"28.5"	"6.92"	"554.42"	"4.63"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00227"	"5693"	"ENSG00000100804"	"PSMB5"	"B2R4N9; B4DUM9; D3DS43; E9PAV2; hsa:5693; P28074; Q16242; Q6PEW2; Q7Z3B5; Q86T01; Q9TNN9"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Separation of Sister Chromatids; The role of GTSE1 in G2/M progression after G2 checkpoint; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"62"	"0"	"3.4"	"3.7"	"4.6"	"3.9"	"0.0"	"2.4"	"5.8"	"6.9"	"10.9"	"31.9"	"89.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8MVJ9"	"Putative histone PARylation factor 1-like OS=Homo sapiens OX=9606 PE=5 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"347"	"39.7"	"8.10"	"445.28"	"4.62"	"1"	"1"	"stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf10228"	""	""	""	""	""	""	"0"	"0"	"31.8"	"30.6"	"33.0"	"50.9"	"37.0"	"31.1"	"82.1"	"77.2"	"142.1"	"574.3"	"854.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07384"	"Calpain-1 catalytic subunit OS=Homo sapiens OX=9606 GN=CAPN1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"714"	"81.8"	"5.67"	"434.41"	"4.62"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00648, Pf01067, Pf13833"	"823"	"ENSG00000014216"	"CAPN1"	"hsa:823; P07384; Q2TTR0; Q6DHV4"	"Integrin-mediated cell adhesion; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Neutrophil degranulation; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"7"	"0"	"16.4"	"15.8"	"20.4"	"28.3"	"18.3"	"19.2"	"22.0"	"37.1"	"42.1"	"116.5"	"219.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5EBL8"	"PDZ domain-containing protein 11 OS=Homo sapiens OX=9606 GN=PDZD11 PE=1 SV=2"	"0.000"	""	"13"	"2"	"4"	"1"	"140"	"16.1"	"7.21"	"641.27"	"4.62"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00595"	"51248"	"ENSG00000120509"	"PDZD11"	"D3DVU3; hsa:51248; Q5EBL8; Q6UWE1; Q9P0Q1"	""	"Ion transport by P-type ATPases; Ion influx/efflux at host-pathogen interface; Transport of vitamins, nucleosides, and related molecules; Biotin transport and metabolism; Vitamin B5 (pantothenate) metabolism"	"5"	"0"	"87.1"	"62.6"	"117.1"	"118.6"	"95.0"	"85.9"	"136.3"	"127.3"	"173.1"	"323.4"	"476.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAV0"	"Guanine nucleotide-binding protein subunit beta-4 OS=Homo sapiens OX=9606 GN=GNB4 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"340"	"37.5"	"6.00"	"382.46"	"4.60"	"1"	"1"	"signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00400"	"59345"	"ENSG00000114450"	"GNB4"	"B3KMH5; D3DNR8; hsa:59345; Q9HAV0"	"Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Ras signaling; Calcium regulation in cardiac cells"	"G alpha (i) signalling events; G alpha (z) signalling events; ADP signalling through P2Y purinoceptor 12; Extra-nuclear estrogen signaling; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; G alpha (12/13) signalling events; G alpha (q) signalling events; Thrombin signalling through proteinase activated receptors (PARs); Activation of G protein gated Potassium channels; G-protein activation; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; G beta:gamma signalling through PI3Kgamma; Prostacyclin signalling through prostacyclin receptor; Adrenaline,noradrenaline inhibits insulin secretion; Ca2+ pathway; G beta:gamma signalling through PLC beta; ADP signalling through P2Y purinoceptor 1; Glucagon-type ligand receptors; Thromboxane signalling through TP receptor; Vasopressin regulates renal water homeostasis via Aquaporins; Presynaptic function of Kainate receptors; Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding; G beta:gamma signalling through BTK; G beta:gamma signalling through CDC42; Inhibition  of voltage gated Ca2+ channels via Gbeta/gamma subunits; Glucagon signaling in metabolic regulation"	"34"	"0"	"14.7"	"13.9"	"12.5"	"15.6"	"14.5"	"11.6"	"22.7"	"27.0"	"36.3"	"127.9"	"182.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P29084"	"Transcription initiation factor IIE subunit beta OS=Homo sapiens OX=9606 GN=GTF2E2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"291"	"33.0"	"9.66"	"366.37"	"4.60"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02186, Pf18121"	"2961"	"ENSG00000197265"	"GTF2E2"	"D3DSV2; hsa:2961; P29084; Q9H2B9"	"Eukaryotic transcription initiation"	"RNA Polymerase II Pre-transcription Events; RNA polymerase II transcribes snRNA genes; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation"	"10"	"0"	"25.6"	"15.0"	"29.4"	"27.3"	"23.6"	"29.0"	"40.3"	"58.2"	"64.9"	"257.0"	"263.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15005"	"Signal peptidase complex subunit 2 OS=Homo sapiens OX=9606 GN=SPCS2 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"226"	"25.0"	"8.47"	"633.06"	"4.60"	"1"	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;ER/Golgi"	""	"Pf06703"	"9789"	"ENSG00000118363"	"SPCS2"	"hsa:9789; Q15005; Q15507; Q3KQT0; Q641R4; Q6FG65; Q6IRX0; Q6P1P4; Q96HU9"	"15q25 copy number variation"	"SRP-dependent cotranslational protein targeting to membrane; Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1); Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP); Synthesis, secretion, and deacylation of Ghrelin"	"5"	"0"	"12.6"	"14.0"	"10.3"	"12.7"	"15.5"	"10.0"	"15.6"	"20.2"	"34.4"	"60.2"	"92.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16333"	"Cytoplasmic protein NCK1 OS=Homo sapiens OX=9606 GN=NCK1 PE=1 SV=1"	"0.000"	""	"7"	"2"	"3"	"1"	"377"	"42.8"	"6.47"	"668.66"	"4.60"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018, Pf14604"	"4690"	"ENSG00000158092"	"NCK1"	"B7Z751; D3DNE3; hsa:4690; P16333"	"Pathogenic Escherichia coli infection; B cell receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Primary focal segmental glomerulosclerosis (FSGS); RAC1/PAK1/p38/MMP2 pathway; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; EGF/EGFR signaling pathway; Genes controlling nephrogenesis; GDNF signaling; ErbB signaling pathway; T-cell receptor signaling pathway"	"Generation of second messenger molecules; RHOU GTPase cycle; Activation of RAC1; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; RHO GTPases Activate WASPs and WAVEs; RHOV GTPase cycle; Nephrin family interactions; DCC mediated attractive signaling; Downstream signal transduction; VEGFA-VEGFR2 Pathway"	"26"	"1"	"39.3"	"30.2"	"47.8"	"58.5"	"28.9"	"42.9"	"118.8"	"141.5"	"286.3"	"1085.8"	"1624.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93096"	"Protein tyrosine phosphatase type IVA 1 OS=Homo sapiens OX=9606 GN=PTP4A1 PE=1 SV=2"	"0.000"	""	"7"	"1"	"3"	"1"	"173"	"19.8"	"8.97"	"925.90"	"4.60"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00782"	"7803"	"ENSG00000112245"	"PTP4A1"	"B2R6C8; hsa:7803; O00648; Q49A54; Q93096"	""	""	"0"	"0"	"37.0"	"30.2"	"50.5"	"73.6"	"38.2"	"43.5"	"73.8"	"80.1"	"131.7"	"258.8"	"333.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BT3"	"Centromere protein T OS=Homo sapiens OX=9606 GN=CENPT PE=1 SV=2"	"0.000"	""	"2"	"1"	"4"	"1"	"561"	"60.4"	"6.58"	"555.98"	"4.60"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15511, Pf16171"	"80152"	"ENSG00000102901"	"CENPT"	"hsa:80152; Q96BT3; Q96I29; Q96IC6; Q96NK9; Q9H901"	""	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Deposition of new CENPA-containing nucleosomes at the centromere"	"7"	"0"	"48.9"	"53.5"	"56.0"	"67.3"	"45.5"	"36.2"	"66.7"	"68.1"	"79.0"	"168.6"	"229.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXY0"	"Protein MAK16 homolog OS=Homo sapiens OX=9606 GN=MAK16 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"300"	"35.3"	"5.38"	"445.96"	"4.60"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01778, Pf04874"	"84549"	"ENSG00000198042"	"MAK16"	"B2RB44; hsa:84549; Q5U5T1; Q86UC4; Q96SY6; Q9BXY0"	""	""	"0"	"0"	"94.9"	"87.8"	"93.1"	"105.7"	"90.6"	"90.6"	"102.3"	"110.2"	"137.0"	"200.6"	"287.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86WA6"	"Valacyclovir hydrolase OS=Homo sapiens OX=9606 GN=BPHL PE=1 SV=1"	"0.000"	""	"6"	"3"	"4"	"3"	"291"	"32.5"	"9.14"	"646.73"	"4.59"	"2"	"2"	"other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00561"	"670"	"ENSG00000137274"	"BPHL"	"hsa:670; Q00306; Q13855; Q3KP51; Q86WA6"	""	"Phase I - Functionalization of compounds"	"1"	"0"	"41.8"	"29.5"	"55.3"	"61.6"	"46.9"	"48.6"	"83.4"	"88.4"	"134.7"	"373.0"	"584.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49407"	"Beta-arrestin-1 OS=Homo sapiens OX=9606 GN=ARRB1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"418"	"47.0"	"6.20"	"492.25"	"4.59"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00339, Pf02752"	"408"	"ENSG00000137486"	"ARRB1"	"B6V9G8; hsa:408; O75625; O75630; P49407; Q2PP20; Q9BTK8"	"Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; Chemokine signaling pathway; Hedgehog signaling pathway; Gastrin signaling pathway; Kisspeptin/kisspeptin receptor system in the ovary; GPR143 in melanocytes and retinal pigment epithelium cells; Calcium regulation in cardiac cells"	"Ub-specific processing proteases; Activation of SMO; Activated NOTCH1 Transmits Signal to the Nucleus; G alpha (s) signalling events; Lysosome Vesicle Biogenesis; Golgi Associated Vesicle Biogenesis; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); Cargo recognition for clathrin-mediated endocytosis; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"25"	"0"	"34.6"	"38.3"	"49.9"	"54.3"	"41.4"	"89.4"	"222.1"	"264.7"	"224.3"	"175.9"	"171.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z4G4"	"tRNA (guanine(10)-N2)-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT11 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"463"	"53.4"	"7.78"	"565.59"	"4.59"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170"	"60487"	"ENSG00000066651"	"TRMT11"	"E1P570; hsa:60487; Q5JY11; Q6PGQ5; Q7Z4G4; Q9HC13"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"29.8"	"27.0"	"28.9"	"43.8"	"20.9"	"27.2"	"52.4"	"57.8"	"83.9"	"266.9"	"390.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60318"	"Germinal-center associated nuclear protein OS=Homo sapiens OX=9606 GN=MCM3AP PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"1980"	"218.3"	"6.39"	"959.48"	"4.56"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03399, Pf16766, Pf16768, Pf16769"	"8888"	"ENSG00000160294"	"MCM3AP"	"C9JL56; hsa:8888; O60318; Q2M3C1; Q6PJP6; Q9BSY5; Q9UMT4"	""	""	"0"	"0"	"52.0"	"54.5"	"64.9"	"72.0"	"48.0"	"53.9"	"97.9"	"90.9"	"144.7"	"331.4"	"433.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6YN16"	"Hydroxysteroid dehydrogenase-like protein 2 OS=Homo sapiens OX=9606 GN=HSDL2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"418"	"45.4"	"7.99"	"392.12"	"4.56"	"1"	"1"	""	"mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf00106, Pf02036"	"84263"	"ENSG00000119471"	"HSDL2"	"A8K1L4; A8K8X1; A8MSV3; hsa:84263; Q658M8; Q6YN16; Q9BT58"	""	""	"0"	"0"	"8.1"	"6.1"	"10.9"	"14.3"	"9.3"	"12.7"	"18.6"	"17.5"	"28.3"	"80.9"	"108.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13042"	"Cell division cycle protein 16 homolog OS=Homo sapiens OX=9606 GN=CDC16 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"620"	"71.6"	"5.85"	"455.58"	"4.56"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf12895, Pf13424"	"8881"	"ENSG00000130177"	"CDC16"	"A2A365; hsa:8881; Q13042; Q5T8C8; Q7Z651; Q96AE6; Q9Y564"	"Cell cycle"	"Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"19"	"0"	"42.2"	"25.6"	"50.7"	"61.2"	"36.6"	"38.0"	"70.5"	"66.5"	"97.5"	"222.9"	"300.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49748"	"Very long-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADVL PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"655"	"70.3"	"8.75"	"396.29"	"4.55"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"37"	"ENSG00000072778"	"ACADVL"	"B4DEB6; F5H2A9; hsa:37; O76056; P49748; Q8WUL0"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation"	"XBP1(S) activates chaperone genes; Beta oxidation of palmitoyl-CoA to myristoyl-CoA"	"4"	"0"	"14.5"	"15.4"	"18.4"	"25.5"	"15.8"	"17.8"	"30.3"	"22.7"	"39.0"	"86.3"	"112.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TF76"	"Serine/threonine-protein kinase haspin OS=Homo sapiens OX=9606 GN=HASPIN PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"798"	"88.4"	"9.16"	""	"4.55"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf12330"	"83903"	"ENSG00000177602"	"HASPIN"	"hsa:83903; Q5U5K3; Q8TF76; Q96MN1; Q9BXS7"	""	""	"0"	"0"	"15.3"	"10.5"	"18.7"	"20.3"	"14.6"	"11.7"	"22.8"	"29.1"	"31.0"	"70.8"	"76.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95166"	"Gamma-aminobutyric acid receptor-associated protein OS=Homo sapiens OX=9606 GN=GABARAP PE=1 SV=1"	"0.000"	""	"16"	"3"	"4"	"2"	"117"	"13.9"	"8.79"	"1099.27"	"4.55"	"3"	"1"	"cell-cell signaling;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf02991"	"11337"	"ENSG00000170296"	"GABARAP"	"hsa:11337; O95166"	"2q37 copy number variation syndrome"	"Macroautophagy; TBC/RABGAPs"	"3"	"0"	"340.6"	"247.9"	"413.3"	"379.3"	"319.2"	"337.7"	"456.5"	"466.3"	"617.4"	"858.0"	"922.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20618"	"Proteasome subunit beta type-1 OS=Homo sapiens OX=9606 GN=PSMB1 PE=1 SV=2"	"0.000"	""	"8"	"1"	"2"	"1"	"241"	"26.5"	"8.13"	"394.48"	"4.54"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	""	"Pf00227"	"5689"	"ENSG00000008018"	"PSMB1"	"B5BU76; hsa:5689; P20618; Q9BWA8"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Neutrophil degranulation; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; MAPK6/MAPK4 signaling; The role of GTSE1 in G2/M progression after G2 checkpoint; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"63"	"0"	"24.4"	"30.0"	"35.4"	"39.1"	"33.6"	"25.0"	"37.7"	"45.8"	"57.1"	"121.3"	"230.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MX6"	"WD repeat-containing protein 92 OS=Homo sapiens OX=9606 GN=WDR92 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"357"	"39.7"	"8.09"	"455.03"	"4.53"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other cell component"	"other molecular function"	"Pf00400"	"116143"	"ENSG00000243667"	"DNAAF10"	"hsa:116143; Q96CR6; Q96MX6"	""	""	"0"	"0"	"38.7"	"33.2"	"41.7"	"47.8"	"32.9"	"37.7"	"62.0"	"70.1"	"104.3"	"208.8"	"303.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUH3"	"RNA-binding protein 45 OS=Homo sapiens OX=9606 GN=RBM45 PE=1 SV=1"	"0.000"	""	"4"	"3"	"5"	"3"	"476"	"53.5"	"7.17"	"774.79"	"4.51"	"3"	"2"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"129831"	"ENSG00000155636"	"RBM45"	"hsa:129831; Q6NYL0; Q8IUH3; Q8NFC9"	""	""	"0"	"0"	"583.3"	"575.5"	"625.5"	"787.9"	"510.5"	"543.3"	"738.8"	"718.6"	"768.0"	"1311.1"	"1806.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96ME7"	"Zinc finger protein 512 OS=Homo sapiens OX=9606 GN=ZNF512 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"567"	"64.6"	"9.76"	"618.33"	"4.51"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"84450"	"ENSG00000243943"	"ZNF512"	"B4DSM5; hsa:84450; Q53RZ7; Q86XK6; Q96JM0; Q96ME7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84098"	"60S ribosomal protein L19 OS=Homo sapiens OX=9606 GN=RPL19 PE=1 SV=1"	"0.000"	""	"12"	"2"	"3"	"1"	"196"	"23.5"	"11.47"	"747.65"	"4.51"	"2"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus;other cell component"	"other molecular function"	"Pf01280"	"6143"	"ENSG00000108298"	"RPL19"	"B2R4K2; hsa:6143; P14118; P22908; P84098; Q502Y6; Q7Z6E4"	"Cytoplasmic ribosomal proteins"	"Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"22.5"	"18.4"	"22.2"	"29.1"	"23.1"	"18.9"	"32.2"	"35.9"	"44.0"	"86.9"	"122.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13418"	"Integrin-linked protein kinase OS=Homo sapiens OX=9606 GN=ILK PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"452"	"51.4"	"8.07"	"272.36"	"4.51"	"1"	"2"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf07714, Pf12796"	"3611"	"ENSG00000166333"	"ILK"	"B7Z1I0; B7Z418; D3DQU0; hsa:3611; P57043; Q13418; Q68DZ3"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; PPAR signaling pathway; Eukaryotic transcription initiation; Endometrial cancer; Acute viral myocarditis; Genes controlling nephrogenesis; Development of ureteric collection system; 2q37 copy number variation syndrome"	"Localization of the PINCH-ILK-PARVIN complex to focal adhesions"	"13"	"0"	"58.0"	"51.1"	"75.3"	"82.6"	"56.0"	"55.5"	"122.1"	"137.6"	"219.2"	"361.1"	"445.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2K7"	"Lysine-specific demethylase 2A OS=Homo sapiens OX=9606 GN=KDM2A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1162"	"132.7"	"7.58"	"507.66"	"4.51"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00646, Pf02008, Pf16866, Pf17811"	"22992"	"ENSG00000173120"	"KDM2A"	"D4QA03; E9PIL6; hsa:22992; I3VM55; Q49A21; Q4G0M3; Q69YY8; Q9BVH5; Q9H7H5; Q9UK66; Q9Y2K7"	""	"HDMs demethylate histones"	"1"	"0"	"27.5"	"27.8"	"30.5"	"37.5"	"20.9"	"23.6"	"37.7"	"46.4"	"49.0"	"118.6"	"132.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86SX6"	"Glutaredoxin-related protein 5, mitochondrial OS=Homo sapiens OX=9606 GN=GLRX5 PE=1 SV=2"	"0.000"	""	"4"	"1"	"4"	"1"	"157"	"16.6"	"6.79"	"486.32"	"4.50"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00462"	"51218"	"ENSG00000182512"	"GLRX5"	"hsa:51218; Q0X088; Q3YML0; Q86SX6; Q86WY3; Q8IZ54"	"Iron-sulfur cluster biogenesis"	"Mitochondrial iron-sulfur cluster biogenesis"	"2"	"0"	"179.8"	"171.4"	"188.2"	"253.1"	"149.7"	"140.2"	"244.3"	"237.0"	"252.8"	"417.6"	"498.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75461"	"Transcription factor E2F6 OS=Homo sapiens OX=9606 GN=E2F6 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"281"	"31.8"	"5.50"	"401.55"	"4.50"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02319, Pf16421"	"1876"	"ENSG00000169016"	"E2F6"	"A8K2Z8; G5E936; hsa:1876; O60544; O75461; Q53QY9; Q6Q9Z6; Q7Z2H6"	""	"Transcriptional Regulation by E2F6; G1/S-Specific Transcription"	"2"	"0"	"24.7"	"21.4"	"24.6"	"26.5"	"18.8"	"27.7"	"34.0"	"36.7"	"53.0"	"121.0"	"139.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07919"	"Cytochrome b-c1 complex subunit 6, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRH PE=1 SV=2"	"0.001"	""	"14"	"2"	"3"	"2"	"91"	"10.7"	"4.44"	"233.04"	"4.50"	"1"	"2"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02320"	"7388"	"ENSG00000173660"	"UQCRH"	"B2R4V9; D3DQ18; hsa:7388; P07919; Q5TDF6; Q6LDB8; Q9BQ91"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	"511.4"	"400.7"	"450.6"	"419.4"	"371.5"	"294.5"	"519.7"	"541.3"	"566.0"	"1008.7"	"1279.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75153"	"Clustered mitochondria protein homolog OS=Homo sapiens OX=9606 GN=CLUH PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1309"	"146.6"	"6.13"	"468.34"	"4.50"	"1"	"1"	"cell organization and biogenesis"	"other cell component"	"nucleic acid binding activity"	"Pf12807, Pf13236, Pf13374, Pf13424, Pf15044"	"23277"	"ENSG00000132361"	"CLUH"	"hsa:23277; O75153; Q6AHY2; Q6P3X7; Q6ZUG8; Q8N4U7; Q9BTA3; Q9H979"	"Translation factors"	""	"1"	"0"	"7.2"	"7.3"	"11.9"	"12.2"	"9.7"	"10.3"	"24.9"	"18.8"	"36.3"	"105.8"	"134.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53985"	"Monocarboxylate transporter 1 OS=Homo sapiens OX=9606 GN=SLC16A1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"500"	"53.9"	"8.66"	"433.85"	"4.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"transporter activity;other molecular function"	"Pf07690"	"6566"	"ENSG00000155380; ENSG00000281917"	"SLC16A1"	"hsa:6566; P53985; Q49A45; Q5T8R6; Q9NSJ9"	"Photodynamic therapy-induced HIF-1 survival signaling; Fragile X syndrome; Glucose metabolism in triple-negative breast cancer cells"	"Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"8"	"0"	"20.7"	"26.4"	"16.1"	"22.6"	"17.1"	"19.6"	"26.3"	"30.4"	"52.1"	"73.2"	"73.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWS9"	"Chitinase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=CHID1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"393"	"44.9"	"8.63"	"690.52"	"4.50"	"2"	"1"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00704"	"66005"	"ENSG00000177830"	"CHID1"	"B3KWB0; hsa:66005; Q8NBM9; Q96CZ3; Q96S93; Q96SK0; Q9BWS9; Q9BY52"	""	"Platelet degranulation"	"1"	"0"	"284.2"	"331.6"	"205.9"	"250.6"	"238.0"	"256.5"	"365.6"	"412.5"	"453.2"	"620.8"	"573.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N9N5"	"Protein BANP OS=Homo sapiens OX=9606 GN=BANP PE=1 SV=3"	""	""	"5"	"1"	"1"	"1"	"519"	"56.5"	"5.49"	""	"4.49"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf10523"	"54971"	"ENSG00000172530"	"BANP"	"A8MU25; A8MX25; B2RCF7; B4DNJ9; F5GZM0; hsa:54971; Q8N9N5; Q96GJ7; Q9NWY1"	""	"Regulation of TP53 Activity through Association with Co-factors"	"1"	"0"	"20.3"	"26.6"	"29.1"	"28.9"	"20.5"	"26.4"	"47.8"	"30.2"	"47.2"	"76.4"	"86.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSD7"	"Cancer-related nucleoside-triphosphatase OS=Homo sapiens OX=9606 GN=NTPCR PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"190"	"20.7"	"9.54"	"442.08"	"4.48"	"1"	"1"	""	""	"other molecular function"	"Pf03266"	"84284"	"ENSG00000135778"	"NTPCR"	"hsa:84284; Q9BSD7"	""	""	"0"	"0"	"22.9"	"19.2"	"31.1"	"44.0"	"26.2"	"25.0"	"32.2"	"36.5"	"35.7"	"84.6"	"101.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NHY2"	"E3 ubiquitin-protein ligase COP1 OS=Homo sapiens OX=9606 GN=COP1 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"731"	"80.4"	"6.84"	"247.54"	"4.48"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00400, Pf13923"	"64326"	"ENSG00000143207"	"COP1"	"E9PKI0; hsa:64326; Q504W6; Q6H103; Q8NHY2; Q9H6L7; X5D9B4"	""	"Neddylation; Autodegradation of the E3 ubiquitin ligase COP1"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNY4"	"Transcription termination factor 2 OS=Homo sapiens OX=9606 GN=TTF2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1162"	"129.5"	"8.37"	"654.07"	"4.48"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf06839"	"8458"	"ENSG00000116830"	"TTF2"	"A8K4Q2; hsa:8458; O75921; Q5T2K7; Q5VVU8; Q8N6I8; Q9UNY4"	"Thyroid stimulating hormone (TSH) signaling pathway; Thyroid hormones production and peripheral downstream signaling effects"	""	"2"	"0"	"36.8"	"30.2"	"40.9"	"46.3"	"41.1"	"26.2"	"59.2"	"63.2"	"93.2"	"208.4"	"310.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P21912"	"Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial OS=Homo sapiens OX=9606 GN=SDHB PE=1 SV=3"	"0.000"	""	"12"	"4"	"5"	"4"	"280"	"31.6"	"8.76"	"1153.75"	"4.47"	"4"	"1"	"other metabolic processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf13085, Pf13534"	"6390"	"ENSG00000117118"	"SDHB"	"B2R545; hsa:6390; P21912; Q0QEY7; Q9NQ12"	"Electron transport chain: OXPHOS system in mitochondria; Metabolic reprogramming in colon cancer; Nonalcoholic fatty liver disease; Mitochondrial complex II assembly; TCA cycle (aka Krebs or citric acid cycle)"	"Respiratory electron transport; Citric acid cycle (TCA cycle)"	"7"	"0"	"334.0"	"338.4"	"305.7"	"378.8"	"256.7"	"219.9"	"467.5"	"503.4"	"633.1"	"1402.3"	"1598.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H0H5"	"Rac GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RACGAP1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"632"	"71.0"	"8.88"	""	"4.46"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00130, Pf00620"	"29127"	"ENSG00000161800"	"RACGAP1"	"hsa:29127; Q6PJ26; Q9H0H5; Q9NWN2; Q9P250; Q9P2W2"	"S1P receptor signal transduction; Wnt signaling pathway and pluripotency"	"CDC42 GTPase cycle; COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; RHOD GTPase cycle"	"13"	"0"	"8.8"	"6.5"	"6.3"	"12.4"	"9.2"	"7.4"	"13.6"	"11.3"	"20.5"	"56.2"	"78.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00264"	"Membrane-associated progesterone receptor component 1 OS=Homo sapiens OX=9606 GN=PGRMC1 PE=1 SV=3"	""	""	"16"	"1"	"1"	"1"	"195"	"21.7"	"4.70"	""	"4.45"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00173"	"10857"	"ENSG00000101856"	"PGRMC1"	"B7Z1L3; hsa:10857; O00264; Q9UGJ9"	"Primary ovarian insufficiency"	"Neutrophil degranulation"	"2"	"0"	"7.9"	"8.7"	"9.6"	"12.1"	"9.7"	"7.9"	"17.4"	"20.9"	"21.9"	"38.7"	"51.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14734"	"Acyl-coenzyme A thioesterase 8 OS=Homo sapiens OX=9606 GN=ACOT8 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"319"	"35.9"	"7.56"	""	"4.45"	""	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf13622"	"10005"	"ENSG00000101473"	"ACOT8"	"hsa:10005; O14734; O15261; Q17RX4"	""	"Peroxisomal protein import; Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol; alpha-linolenic acid (ALA) metabolism; Beta-oxidation of pristanoyl-CoA; Beta-oxidation of very long chain fatty acids"	"5"	"0"	"33.9"	"25.8"	"37.8"	"48.0"	"34.3"	"33.2"	"48.2"	"49.0"	"69.4"	"139.0"	"173.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD1"	"39S ribosomal protein L13, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL13 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"178"	"20.7"	"9.16"	"490.26"	"4.43"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00572"	"28998"	"ENSG00000172172"	"MRPL13"	"B2R4R8; hsa:28998; Q9BYD1; Q9UI04"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"25.8"	"22.8"	"24.9"	"28.1"	"21.5"	"19.8"	"29.8"	"34.7"	"37.3"	"68.5"	"104.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75962"	"Triple functional domain protein OS=Homo sapiens OX=9606 GN=TRIO PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"3097"	"346.7"	"6.37"	"428.05"	"4.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00018, Pf00069, Pf00169, Pf00435, Pf00621, Pf00650, Pf07679, Pf16609"	"7204"	"ENSG00000038382"	"TRIO"	"D3DTD1; hsa:7204; O75962; Q13458; Q59EQ7; Q6PJC9; Q6ZN05; Q8IWK8"	"Microtubule cytoskeleton regulation; Neural crest cell migration during development; Neural crest cell migration in cancer"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; G alpha (q) signalling events; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOJ GTPase cycle; DCC mediated attractive signaling"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6M4"	"Casein kinase I isoform gamma-3 OS=Homo sapiens OX=9606 GN=CSNK1G3 PE=1 SV=2"	"0.000"	""	"4"	"2"	"4"	"2"	"447"	"51.4"	"9.22"	"544.69"	"4.42"	"2"	"2"	"cell-cell signaling;protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf12605"	"1456"	"ENSG00000151292"	"CSNK1G3"	"A8K040; B4DSH2; B7Z9Q4; E7EVD0; hsa:1456; Q86WZ7; Q9Y6M3; Q9Y6M4"	"Hedgehog signaling pathway"	""	"1"	"0"	"27.0"	"25.2"	"30.6"	"43.6"	"30.9"	"24.2"	"69.3"	"65.0"	"104.2"	"417.3"	"577.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13895"	"Bystin OS=Homo sapiens OX=9606 GN=BYSL PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"437"	"49.6"	"8.12"	"554.79"	"4.41"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05291"	"705"	"ENSG00000112578"	"BYSL"	"hsa:705; Q13895; Q6P5W4; Q86W44; Q96IP8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"18.6"	"17.1"	"23.7"	"25.8"	"13.7"	"16.7"	"32.5"	"28.1"	"36.7"	"68.7"	"78.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UE8"	"Serine/threonine-protein kinase tousled-like 2 OS=Homo sapiens OX=9606 GN=TLK2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"772"	"87.6"	"8.41"	"683.43"	"4.40"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"11011"	"ENSG00000146872"	"TLK2"	"D3DU07; hsa:11011; Q86UE8; Q9UKI7; Q9Y4F7"	"miRNA regulation of DNA damage response; DNA damage response"	""	"2"	"0"	"5.6"	"3.9"	"5.3"	"8.3"	"7.6"	"5.5"	"7.7"	"12.9"	"9.8"	"22.4"	"29.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GN5"	"Cell division cycle-associated 7-like protein OS=Homo sapiens OX=9606 GN=CDCA7L PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"454"	"52.2"	"5.74"	"260.23"	"4.40"	"1"	"2"	"other biological processes"	"cytosol;nucleus"	""	"Pf10497"	"55536"	"ENSG00000164649"	"CDCA7L"	"A4D141; A6NF50; B3KTR5; B4DUT3; C9K0Y1; hsa:55536; Q6PIL4; Q86YT0; Q8IXN5; Q96C70; Q96GN5; Q9H9A2; Q9NPV2"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"19.7"	"14.4"	"20.9"	"26.4"	"20.7"	"16.4"	"27.0"	"28.4"	"33.8"	"68.3"	"75.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76080"	"AN1-type zinc finger protein 5 OS=Homo sapiens OX=9606 GN=ZFAND5 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"213"	"23.1"	"8.51"	"424.58"	"4.38"	"1"	"1"	"developmental processes;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01428, Pf01754"	"7763"	"ENSG00000107372"	"ZFAND5"	"A8K484; hsa:7763; O76080"	""	""	"0"	"0"	"29.5"	"18.7"	"30.2"	"31.3"	"27.6"	"25.1"	"52.3"	"49.3"	"69.2"	"116.1"	"132.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43678"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2 OS=Homo sapiens OX=9606 GN=NDUFA2 PE=1 SV=3"	""	""	"21"	"1"	"1"	"1"	"99"	"10.9"	"9.57"	""	"4.38"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport;developmental processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf05047"	"4695"	"ENSG00000131495"	"NDUFA2"	"D6RJD6; hsa:4695; O43678; Q6IAY8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"14.1"	"16.0"	"13.0"	"19.4"	"14.0"	"9.4"	"20.3"	"20.8"	"29.2"	"57.3"	"67.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPU6"	"Dihydropyrimidinase-related protein 5 OS=Homo sapiens OX=9606 GN=DPYSL5 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"564"	"61.4"	"7.20"	"285.23"	"4.36"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf01979"	"56896"	"ENSG00000157851"	"DPYSL5"	"hsa:56896; Q8TCL6; Q9BPU6; Q9NQC4; Q9NRY9"	""	"CRMPs in Sema3A signaling"	"1"	"0"	"37.3"	"36.9"	"44.5"	"51.4"	"32.4"	"32.0"	"86.8"	"88.8"	"130.5"	"612.7"	"1042.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15392"	"Baculoviral IAP repeat-containing protein 5 OS=Homo sapiens OX=9606 GN=BIRC5 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"142"	"16.4"	"5.90"	"366.64"	"4.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00653"	"332"	"ENSG00000089685"	"BIRC5"	"A2SUH6; B2R4R1; hsa:332; O15392; Q2I3N8; Q4VGX0; Q53F61; Q5MGC6; Q6FHL2; Q75SP2; Q9P2W8"	"Apoptosis modulation and signaling; Interleukin-11 signaling pathway; Apoptosis; Apoptosis-related network due to altered Notch3 in ovarian cancer; RAC1/PAK1/p38/MMP2 pathway; Photodynamic therapy-induced HIF-1 survival signaling; Photodynamic therapy-induced NF-kB survival signaling; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; IL-4 signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Extracellular vesicles in the crosstalk of cardiac cells; Gastrin signaling pathway; Hepatitis B infection"	"Separation of Sister Chromatids; Neddylation; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Interleukin-4 and Interleukin-13 signaling; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain"	"24"	"0"	"58.3"	"49.5"	"74.8"	"105.9"	"56.2"	"48.9"	"101.7"	"95.7"	"118.6"	"178.7"	"239.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53999"	"Activated RNA polymerase II transcriptional coactivator p15 OS=Homo sapiens OX=9606 GN=SUB1 PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"127"	"14.4"	"9.60"	"358.07"	"4.36"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02229"	"10923"	"ENSG00000113387"	"SUB1"	"hsa:10923; P53999; Q96L29"	""	""	"0"	"0"	"79.0"	"70.0"	"95.2"	"114.0"	"88.3"	"84.6"	"114.7"	"112.8"	"157.6"	"383.3"	"756.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NRW3"	"DNA dC->dU-editing enzyme APOBEC-3C OS=Homo sapiens OX=9606 GN=APOBEC3C PE=1 SV=2"	""	""	"8"	"1"	"1"	"1"	"190"	"22.8"	"7.59"	""	"4.36"	""	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf18782"	"27350"	"ENSG00000244509"	"APOBEC3C"	"B2R884; hsa:27350; Q5JZ92; Q7Z2N7; Q96F12; Q9NRW3"	""	"Formation of the Editosome"	"2"	"0"	"22.7"	"8.9"	"17.4"	"31.3"	"16.5"	"13.3"	"28.6"	"31.1"	"38.3"	"92.1"	"139.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPF5"	"DNA methyltransferase 1-associated protein 1 OS=Homo sapiens OX=9606 GN=DMAP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"467"	"53.0"	"9.50"	"533.89"	"4.35"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf05499, Pf16282"	"55929"	"ENSG00000178028"	"DMAP1"	"A8K001; D3DPY8; hsa:55929; Q0JSM4; Q5TG41; Q7Z3H7; Q9H0S8; Q9NPF5; Q9P2C2"	""	"HATs acetylate histones"	"1"	"0"	"60.9"	"59.2"	"70.6"	"80.9"	"64.6"	"64.2"	"100.8"	"105.6"	"124.9"	"238.9"	"348.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14497"	"AT-rich interactive domain-containing protein 1A OS=Homo sapiens OX=9606 GN=ARID1A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2285"	"241.9"	"6.70"	"569.09"	"4.35"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01388, Pf12031"	"8289"	"ENSG00000117713"	"ARID1A"	"D3DPL1; hsa:8289; O14497; Q53FK9; Q5T0W1; Q5T0W2; Q5T0W3; Q8NFD6; Q96T89; Q9BY33; Q9HBJ5; Q9UPZ1"	"Androgen receptor network in prostate cancer; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"7"	"0"	"9.4"	"7.9"	"7.9"	"9.4"	"9.3"	"6.1"	"11.5"	"14.5"	"17.8"	"37.7"	"47.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXW9"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 4 OS=Homo sapiens OX=9606 GN=ALKBH4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"302"	"33.8"	"6.67"	"491.35"	"4.35"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"54784"	"ENSG00000160993"	"ALKBH4"	"hsa:54784; Q53H92; Q9H6A4; Q9NXW9"	""	""	"0"	"0"	"62.1"	"62.8"	"66.6"	"81.9"	"55.0"	"52.3"	"221.5"	"239.9"	"355.7"	"608.7"	"515.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0B5"	"Palmitoyltransferase ZDHHC5 OS=Homo sapiens OX=9606 GN=ZDHHC5 PE=1 SV=2"	"0.000"	""	"5"	"2"	"2"	"2"	"715"	"77.5"	"9.01"	"286.14"	"4.34"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf01529"	"25921"	"ENSG00000156599"	"ZDHHC5"	"hsa:25921; Q2TGF0; Q6ZMF0; Q8TAK8; Q9C0B5; Q9H923; Q9UFI7"	""	"Maturation of spike protein"	"1"	"0"	"91.7"	"70.4"	"82.2"	"82.7"	"54.5"	"79.6"	"107.9"	"103.6"	"158.2"	"345.8"	"532.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12929"	"Epidermal growth factor receptor kinase substrate 8 OS=Homo sapiens OX=9606 GN=EPS8 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"822"	"91.8"	"7.50"	"623.84"	"4.32"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00018, Pf08416, Pf18016"	"2059"	"ENSG00000151491"	"EPS8"	"A6NMC3; A8K6W2; A8KA66; B4DX66; hsa:2059; Q12929; Q8N6J0"	"EGF/EGFR signaling pathway; IL-18 signaling pathway"	"Sensory processing of sound by inner hair cells of the cochlea; Sensory processing of sound by outer hair cells of the cochlea"	"4"	"0"	"44.1"	"15.9"	"42.8"	"67.9"	"38.3"	"42.3"	"50.6"	"41.4"	"45.2"	"56.9"	"72.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A8MT69"	"Centromere protein X OS=Homo sapiens OX=9606 GN=CENPX PE=1 SV=1"	"0.000"	""	"17"	"1"	"2"	"1"	"81"	"9.0"	"5.90"	"456.05"	"4.32"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf09415"	"201254"	"ENSG00000169689"	"CENPX"	"A8MT69; hsa:201254; O00281; O00282; Q96DD4; Q96F51"	"DNA repair pathways, full network"	"Fanconi Anemia Pathway; Deposition of new CENPA-containing nucleosomes at the centromere"	"3"	"0"	"5.0"	"3.0"	"5.4"	"11.4"	"4.9"	"5.5"	"27.2"	"26.9"	"55.2"	"279.8"	"452.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9C0B0"	"RING finger protein unkempt homolog OS=Homo sapiens OX=9606 GN=UNK PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"810"	"88.0"	"6.86"	"385.48"	"4.30"	"1"	"1"	"developmental processes;other biological processes"	"other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00642, Pf18384"	"85451"	"ENSG00000132478"	"UNK"	"hsa:85451; Q9C0B0"	""	""	"0"	"0"	"43.0"	"44.5"	"34.1"	"44.3"	"37.0"	"33.5"	"55.7"	"54.6"	"60.9"	"92.1"	"114.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2N5"	"RNA-binding protein 27 OS=Homo sapiens OX=9606 GN=RBM27 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"1060"	"118.6"	"9.19"	"971.77"	"4.29"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00076, Pf00642, Pf01480"	"54439"	"ENSG00000091009"	"RBM27"	"hsa:54439; Q8IYW9; Q9P2N5"	""	""	"0"	"0"	"25.8"	"23.7"	"31.2"	"42.4"	"35.1"	"22.8"	"49.0"	"61.2"	"82.2"	"238.5"	"335.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5PRF9"	"Protein Smaug homolog 2 OS=Homo sapiens OX=9606 GN=SAMD4B PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"694"	"75.4"	"6.83"	"474.98"	"4.29"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536"	"55095"	"ENSG00000179134"	"SAMD4B"	"A5Z0M6; hsa:55095; Q5PRF9; Q6P194"	""	""	"0"	"0"	"6.0"	"6.9"	"8.7"	"8.9"	"5.0"	"7.2"	"12.6"	"19.9"	"21.8"	"47.2"	"71.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VVJ2"	"Histone H2A deubiquitinase MYSM1 OS=Homo sapiens OX=9606 GN=MYSM1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"828"	"95.0"	"5.53"	"433.02"	"4.29"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf01398, Pf04433"	"114803"	"ENSG00000162601"	"MYSM1"	"A8KA54; B3KX65; hsa:114803; Q5VVJ2; Q68DD3; Q6AI53; Q7Z3G8; Q96PX3"	""	"Metalloprotease DUBs"	"1"	"0"	"0.0"	"0.0"	"0.0"	"5.5"	"0.0"	"3.2"	"4.1"	"8.1"	"11.1"	"45.1"	"70.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYB9"	"Abl interactor 2 OS=Homo sapiens OX=9606 GN=ABI2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"513"	"55.6"	"6.16"	"343.92"	"4.29"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf07815, Pf14604"	"10152"	"ENSG00000138443"	"ABI2"	"B4DSN1; hsa:10152; Q13147; Q13249; Q13801; Q9BV70; Q9NYB9"	"Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; VEGFA-VEGFR2 Pathway"	"8"	"0"	"47.7"	"48.5"	"54.1"	"63.8"	"43.0"	"53.6"	"96.6"	"91.3"	"144.9"	"290.5"	"378.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94813"	"Slit homolog 2 protein OS=Homo sapiens OX=9606 GN=SLIT2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1529"	"169.8"	"7.06"	"433.51"	"4.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00008, Pf01462, Pf01463, Pf02210, Pf12661, Pf13855"	"9353"	"ENSG00000145147"	"SLIT2"	"A0A0A6YYB8; B7ZLR5; hsa:9353; O94813; O95710; Q17RU3; Q9Y5Q7"	"Spinal cord injury; Robo4 and VEGF signaling pathways crosstalk; Genes controlling nephrogenesis; GDNF/RET signaling axis; Development of ureteric collection system"	"Regulation of expression of SLITs and ROBOs; Netrin-1 signaling; Inactivation of CDC42 and RAC1; Activation of RAC1; Regulation of commissural axon pathfinding by SLIT and ROBO; Role of ABL in ROBO-SLIT signaling; SLIT2:ROBO1 increases RHOA activity"	"13"	"0"	"12.6"	"13.3"	"14.3"	"19.6"	"13.5"	"16.0"	"26.7"	"28.7"	"32.5"	"69.2"	"108.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96017"	"Serine/threonine-protein kinase Chk2 OS=Homo sapiens OX=9606 GN=CHEK2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"543"	"60.9"	"5.91"	"479.60"	"4.29"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00498"	"11200"	"ENSG00000183765"	"CHEK2"	"A8K3Y9; B7ZBF3; B7ZBF4; B7ZBF5; hsa:11200; O96017; Q6QA03; Q6QA04; Q6QA05; Q6QA06; Q6QA07; Q6QA08; Q6QA10; Q6QA11; Q6QA12; Q6QA13; Q9HBS5; Q9HCQ8; Q9UGF0; Q9UGF1"	"miRNA regulation of DNA damage response; Cell cycle; ATM signaling in development and disease ; miRNA regulation of p53 pathway in prostate cancer; DNA damage response"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Regulation of TP53 Degradation; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Regulation of TP53 Activity through Phosphorylation; Regulation of TP53 Activity through Methylation; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; Stabilization of p53"	"13"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.6"	"2.7"	"2.4"	"31.0"	"81.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P00918"	"Carbonic anhydrase 2 OS=Homo sapiens OX=9606 GN=CA2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"260"	"29.2"	"7.40"	"376.61"	"4.28"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00194"	"760"	"ENSG00000104267"	"CA2"	"B2R7G8; hsa:760; P00918; Q6FI12; Q96ET9"	"Proximal tubule transport"	"Reversible hydration of carbon dioxide; Erythrocytes take up carbon dioxide and release oxygen; Erythrocytes take up oxygen and release carbon dioxide"	"4"	"0"	"12.4"	"11.7"	"27.5"	"30.0"	"7.7"	"9.1"	"16.6"	"22.1"	"26.1"	"60.3"	"83.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2Z2"	"Elongation factor-like GTPase 1 OS=Homo sapiens OX=9606 GN=EFL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1120"	"125.4"	"5.91"	"396.28"	"4.28"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf00679, Pf14492"	"79631"	"ENSG00000140598"	"EFL1"	"A6NKY5; B7Z6I0; hsa:79631; Q7Z2Z2; Q9H8Z6"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	"3.9"	"5.5"	"6.8"	"4.8"	"2.1"	"1.9"	"8.3"	"14.1"	"18.2"	"293.0"	"450.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVF7"	"Formin-like protein 3 OS=Homo sapiens OX=9606 GN=FMNL3 PE=1 SV=3"	"0.001"	""	"3"	"2"	"3"	"1"	"1028"	"117.1"	"6.65"	"246.48"	"4.28"	"1"	"2"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"91010"	"ENSG00000161791"	"FMNL3"	"B0JZA7; hsa:91010; Q6ZRJ1; Q8IVF7"	"VEGFA-VEGFR2 signaling"	"RHOJ GTPase cycle; RHO GTPases Activate Formins; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle"	"6"	"0"	"34.3"	"44.6"	"38.7"	"63.6"	"33.4"	"66.0"	"46.5"	"38.2"	"61.2"	"135.6"	"197.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q99961"	"Endophilin-A2 OS=Homo sapiens OX=9606 GN=SH3GL1 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"368"	"41.5"	"5.43"	""	"4.27"	""	"1"	"cell organization and biogenesis;transport;developmental processes;signal transduction"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00018, Pf03114"	"6455"	"ENSG00000141985"	"SH3GL1"	"B4DRA1; E7EVZ4; hsa:6455; M0QZV5; Q99668; Q99961"	"Fragile X syndrome"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"6"	"0"	"14.5"	"12.1"	"20.8"	"32.6"	"14.1"	"11.1"	"25.6"	"30.7"	"42.9"	"375.3"	"1228.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZN1"	"Actin-related protein 6 OS=Homo sapiens OX=9606 GN=ACTR6 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"396"	"45.8"	"5.03"	"357.86"	"4.27"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00022"	"64431"	"ENSG00000075089"	"ACTR6"	"B3KW37; B4DLG9; hsa:64431; Q53GH2; Q9BY39; Q9GZN1; Q9H8H6"	""	""	"0"	"0"	"14.5"	"13.4"	"24.6"	"28.6"	"14.9"	"15.8"	"38.1"	"31.5"	"48.1"	"274.9"	"366.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14331"	"Protein FRG1 OS=Homo sapiens OX=9606 GN=FRG1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"258"	"29.2"	"9.01"	"385.53"	"4.27"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf06229"	"2483"	"ENSG00000109536; ENSG00000275145; ENSG00000283153; ENSG00000283630"	"FRG1"	"A8K775; hsa:2483; Q14331"	""	""	"0"	"0"	"24.5"	"18.4"	"32.8"	"45.5"	"22.4"	"26.7"	"72.5"	"78.9"	"148.8"	"204.2"	"164.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86X10"	"Ral GTPase-activating protein subunit beta OS=Homo sapiens OX=9606 GN=RALGAPB PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1494"	"166.7"	"6.79"	"447.44"	"4.26"	"1"	"1"	"other biological processes"	""	"enzyme regulator activity;other molecular function"	"Pf20412"	"57148"	"ENSG00000170471"	"RALGAPB"	"A2A2E8; A2A2E9; hsa:57148; Q5TG31; Q86X10; Q8N3D1; Q8WWC0; Q9H3X8; Q9UJR1; Q9ULK1; Q9Y3G9"	""	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"1"	"0"	"9.6"	"8.7"	"14.8"	"11.0"	"10.8"	"11.0"	"52.9"	"59.9"	"74.1"	"146.2"	"169.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02241"	"Kinesin-like protein KIF23 OS=Homo sapiens OX=9606 GN=KIF23 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"960"	"110.0"	"8.51"	"620.97"	"4.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf16540"	"9493"	"ENSG00000137807"	"KIF23"	"B4E1K0; hsa:9493; Q02241; Q8WVP0"	"Pleural mesothelioma"	"MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; Mitotic Telophase/Cytokinesis"	"5"	"0"	"22.3"	"9.7"	"31.1"	"40.5"	"23.7"	"14.8"	"38.5"	"33.5"	"50.5"	"66.9"	"99.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y692"	"Glucocorticoid modulatory element-binding protein 1 OS=Homo sapiens OX=9606 GN=GMEB1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"4"	"2"	"573"	"62.6"	"4.83"	"527.82"	"4.26"	"2"	"2"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01342"	"10691"	"ENSG00000162419"	"GMEB1"	"B1AT48; hsa:10691; Q9NWH1; Q9UKD0; Q9Y692"	"2q37 copy number variation syndrome"	""	"1"	"0"	"19.2"	"18.9"	"22.9"	"19.2"	"13.2"	"11.6"	"34.7"	"27.9"	"56.8"	"203.7"	"304.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y5K5"	"Ubiquitin carboxyl-terminal hydrolase isozyme L5 OS=Homo sapiens OX=9606 GN=UCHL5 PE=1 SV=3"	""	""	"10"	"1"	"1"	"1"	"329"	"37.6"	"5.33"	""	"4.25"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01088, Pf18031"	"51377"	"ENSG00000116750"	"UCHL5"	"hsa:51377; Q5LJA6; Q5LJA7; Q8TBS4; Q96BJ9; Q9H1W5; Q9P0I3; Q9UQN2; Q9Y5K5"	""	"UCH proteinases; Downregulation of TGF-beta receptor signaling"	"2"	"0"	"3.3"	"5.4"	"6.4"	"4.8"	"7.3"	"7.2"	"6.5"	"8.6"	"11.9"	"36.4"	"37.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y223"	"Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase OS=Homo sapiens OX=9606 GN=GNE PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"722"	"79.2"	"6.80"	"487.80"	"4.25"	"1"	"1"	"cell adhesion;other metabolic processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00480, Pf02350"	"10020"	"ENSG00000159921"	"GNE"	"A6PZH2; A6PZH3; A7UNU7; B2R6E1; B7Z372; B7Z428; D3DRP7; F5H499; H0YFA7; hsa:10020; Q0VA94; Q9Y223"	""	"Sialic acid metabolism; Defective GNE causes sialuria, NK and IBM2"	"2"	"0"	"18.0"	"19.1"	"18.9"	"24.6"	"14.1"	"12.6"	"26.6"	"26.5"	"44.7"	"145.1"	"259.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15182"	"Centrin-3 OS=Homo sapiens OX=9606 GN=CETN3 PE=1 SV=2"	"0.000"	""	"12"	"1"	"2"	"1"	"167"	"19.5"	"4.74"	"583.12"	"4.25"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1070"	"ENSG00000153140"	"CETN3"	"hsa:1070; O15182; Q53YD2; Q9BS23"	"Breast cancer pathway"	""	"1"	"0"	"12.5"	"8.0"	"20.0"	"23.2"	"16.4"	"15.6"	"50.0"	"56.6"	"83.0"	"140.9"	"178.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969G3"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1 OS=Homo sapiens OX=9606 GN=SMARCE1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"411"	"46.6"	"4.88"	"277.45"	"4.25"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505"	"6605"	"ENSG00000073584"	"SMARCE1"	"B3KMC1; B4DFR4; C0IMW4; C0IMW5; C0IMW7; H7C3F6; hsa:6605; O43539; Q969G3"	"Androgen receptor signaling pathway; Pathways affected in adenoid cystic carcinoma; Tumor suppressor activity of SMARCB1; Thermogenesis"	"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; RMTs methylate histone arginines"	"6"	"0"	"74.9"	"63.4"	"86.9"	"119.6"	"76.4"	"77.1"	"127.5"	"138.8"	"188.9"	"536.5"	"719.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8H2"	"Probable ATP-dependent RNA helicase DDX31 OS=Homo sapiens OX=9606 GN=DDX31 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"851"	"94.0"	"9.99"	"589.98"	"4.24"	"1"	"1"	"other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"64794"	"ENSG00000125485"	"DDX31"	"hsa:64794; Q5K6N2; Q5K6N3; Q5K6N4; Q5VZJ4; Q5VZJ9; Q96E91; Q96NY2; Q96SX5; Q9H5K6; Q9H8H2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35244"	"Replication protein A 14 kDa subunit OS=Homo sapiens OX=9606 GN=RPA3 PE=1 SV=1"	"0.000"	""	"14"	"1"	"2"	"1"	"121"	"13.6"	"5.08"	"390.67"	"4.24"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf08661"	"6119"	"ENSG00000106399"	"RPA3"	"hsa:6119; P35244; Q549U6"	"Retinoblastoma gene in cancer; G1 to S cell cycle control; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"HSF1 activation; Fanconi Anemia Pathway; Regulation of HSF1-mediated heat shock response; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Meiotic recombination; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Formation of Incision Complex in GG-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Removal of the Flap Intermediate; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"36"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15181"	"Inorganic pyrophosphatase OS=Homo sapiens OX=9606 GN=PPA1 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"289"	"32.6"	"5.86"	""	"4.24"	""	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00719"	"5464"	"ENSG00000180817"	"PPA1"	"hsa:5464; Q15181; Q2M348; Q5SQT7; Q6P7P4; Q9UQJ5; Q9Y5B1"	""	"Cytosolic tRNA aminoacylation; Pyrophosphate hydrolysis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13625"	"Apoptosis-stimulating of p53 protein 2 OS=Homo sapiens OX=9606 GN=TP53BP2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1128"	"125.5"	"6.07"	"410.23"	"4.24"	"1"	"1"	"cell cycle OR cell proliferation;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00018, Pf00023"	"7159"	"ENSG00000143514"	"TP53BP2"	"B4DG66; hsa:7159; Q12892; Q13625; Q86X75; Q96KQ3"	""	"TP53 Regulates Transcription of Death Receptors and Ligands; Activation of PUMA and translocation to mitochondria; TP53 Regulates Transcription of Genes Involved in Cytochrome C Release; TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain; Regulation of TP53 Activity through Association with Co-factors"	"5"	"0"	"40.7"	"36.3"	"51.4"	"72.0"	"42.3"	"48.6"	"78.7"	"74.8"	"116.0"	"217.9"	"284.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60343"	"TBC1 domain family member 4 OS=Homo sapiens OX=9606 GN=TBC1D4 PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"1298"	"146.5"	"7.01"	"733.57"	"4.24"	"2"	"1"	"transport;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00566, Pf00640, Pf11830"	"9882"	"ENSG00000136111"	"TBC1D4"	"A7E2X8; B4DU25; B4E235; B6ETN8; B6ETN9; hsa:9882; O60343; Q5W0B9; Q68D14"	"Ciliary landscape; Thyroid hormones production and peripheral downstream signaling effects; Insulin signaling"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane"	"4"	"0"	"152.0"	"102.7"	"146.5"	"189.4"	"113.7"	"117.9"	"227.6"	"195.7"	"284.5"	"1347.5"	"2026.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5C9Z4"	"Nucleolar MIF4G domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NOM1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"860"	"96.2"	"8.10"	"479.11"	"4.24"	"1"	"1"	"other biological processes"	"nucleus"	""	"Pf02847, Pf02854"	"64434"	"ENSG00000146909"	"NOM1"	"hsa:64434; Q5C9Z4; Q96I08"	""	""	"0"	"0"	"42.9"	"44.0"	"52.9"	"65.8"	"42.6"	"56.7"	"72.1"	"85.2"	"106.7"	"194.0"	"296.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P36915"	"Guanine nucleotide-binding protein-like 1 OS=Homo sapiens OX=9606 GN=GNL1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"607"	"68.6"	"5.80"	"449.33"	"4.23"	"1"	"1"	"stress response;signal transduction;other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf01926"	"2794"	"ENSG00000204590; ENSG00000206492; ENSG00000226882; ENSG00000228581; ENSG00000229470; ENSG00000232143; ENSG00000235986"	"GNL1"	"B0S838; hsa:2794; P36915; Q96CT5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYD2"	"39S ribosomal protein L9, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL9 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"267"	"30.2"	"10.08"	"427.74"	"4.23"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01281"	"65005"	"ENSG00000143436"	"MRPL9"	"B2RD99; hsa:65005; Q5SZR2; Q9BSW8; Q9BYD2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"48.1"	"41.3"	"54.9"	"60.3"	"48.4"	"66.9"	"106.2"	"94.6"	"119.4"	"214.5"	"294.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T447"	"E3 ubiquitin-protein ligase HECTD3 OS=Homo sapiens OX=9606 GN=HECTD3 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"861"	"97.1"	"5.64"	"917.54"	"4.22"	"2"	"1"	"protein metabolism;other metabolic processes"	"other cell component"	"other molecular function"	"Pf00632, Pf03256"	"79654"	"ENSG00000126107"	"HECTD3"	"B3KPV7; B3KRH4; hsa:79654; Q5T447; Q5T448; Q9H783"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"6.2"	"5.4"	"6.0"	"9.9"	"5.4"	"4.0"	"14.3"	"12.3"	"26.4"	"64.1"	"86.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IUR0"	"Trafficking protein particle complex subunit 5 OS=Homo sapiens OX=9606 GN=TRAPPC5 PE=1 SV=1"	"0.001"	""	"10"	"1"	"2"	"1"	"188"	"20.8"	"9.66"	"247.45"	"4.22"	"1"	"1"	"cell organization and biogenesis;transport"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"126003"	"ENSG00000181029"	"TRAPPC5"	"A8K7I6; hsa:126003; Q8IUR0"	""	"COPII-mediated vesicle transport; RAB GEFs exchange GTP for GDP on RABs"	"2"	"0"	"23.8"	"26.1"	"31.7"	"47.3"	"29.4"	"36.0"	"74.1"	"84.1"	"136.7"	"377.8"	"473.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRT2"	"Ubiquinol-cytochrome-c reductase complex assembly factor 2 OS=Homo sapiens OX=9606 GN=UQCC2 PE=1 SV=1"	"0.000"	""	"15"	"2"	"3"	"2"	"126"	"14.9"	"7.37"	"649.38"	"4.17"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion;nucleus"	""	"Pf20180"	"84300"	"ENSG00000137288"	"UQCC2"	"B2R4I0; hsa:84300; Q9BRT2"	"Mitochondrial complex III assembly"	""	"1"	"0"	"91.7"	"95.0"	"96.6"	"120.5"	"95.7"	"84.2"	"201.4"	"240.7"	"352.7"	"663.3"	"630.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNL4"	"Inhibitor of growth protein 4 OS=Homo sapiens OX=9606 GN=ING4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"249"	"28.5"	"7.62"	"313.28"	"4.17"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf12998"	"51147"	"ENSG00000111653"	"ING4"	"A4KYM4; A4KYM6; D3DUR8; hsa:51147; Q0EF62; Q0EF63; Q4VBQ6; Q96E15; Q9H3J0; Q9UNL4"	""	"HATs acetylate histones"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB5"	"Stromal membrane-associated protein 1 OS=Homo sapiens OX=9606 GN=SMAP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"467"	"50.4"	"8.75"	"396.18"	"4.16"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01412"	"60682"	"ENSG00000112305"	"SMAP1"	"hsa:60682; Q53H70; Q5SYQ2; Q6PK24; Q8IYB5; Q8NDH4; Q96L38; Q96L39; Q9H8X4"	""	""	"0"	"0"	"51.9"	"40.7"	"41.6"	"64.0"	"43.6"	"29.2"	"71.1"	"78.2"	"104.9"	"219.4"	"256.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WXI9"	"Transcriptional repressor p66-beta OS=Homo sapiens OX=9606 GN=GATAD2B PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"593"	"65.2"	"9.70"	"592.63"	"4.16"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"57459"	"ENSG00000143614; ENSG00000261992"	"GATAD2B"	"D3DUZ2; hsa:57459; Q5VUR2; Q7LG68; Q8WXI9; Q9ULS0"	""	"RNA Polymerase I Transcription Initiation; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Regulation of TP53 Activity through Acetylation"	"6"	"0"	"232.8"	"207.9"	"216.7"	"269.2"	"188.9"	"215.8"	"291.8"	"306.7"	"354.7"	"639.3"	"791.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYB0"	"Telomeric repeat-binding factor 2-interacting protein 1 OS=Homo sapiens OX=9606 GN=TERF2IP PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"399"	"44.2"	"4.73"	"492.36"	"4.16"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08914, Pf11626, Pf16589"	"54386"	"ENSG00000166848"	"TERF2IP"	"B4DQN4; hsa:54386; Q4W4Y2; Q8WYZ3; Q9NWR2; Q9NYB0"	"Splicing factor NOVA regulated synaptic proteins; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction"	"DNA Damage/Telomere Stress Induced Senescence; Meiotic synapsis; Inhibition of DNA recombination at telomere; Recognition and association of DNA glycosylase with site containing an affected purine; Recognition and association of DNA glycosylase with site containing an affected pyrimidine; Cleavage of the damaged pyrimidine ; Cleavage of the damaged purine; Packaging Of Telomere Ends; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; Telomere Extension By Telomerase; Removal of the Flap Intermediate from the C-strand"	"16"	"0"	"29.0"	"28.4"	"27.4"	"33.4"	"28.2"	"27.2"	"47.1"	"44.5"	"50.1"	"131.9"	"193.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H081"	"Protein MIS12 homolog OS=Homo sapiens OX=9606 GN=MIS12 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"205"	"24.1"	"5.69"	"351.77"	"4.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf05859"	"79003"	"ENSG00000167842"	"MIS12"	"hsa:79003; Q96N24; Q9H081"	""	"Resolution of Sister Chromatid Cohesion; Separation of Sister Chromatids; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"37.3"	"29.1"	"29.4"	"30.5"	"24.1"	"29.1"	"66.5"	"69.1"	"99.2"	"239.8"	"286.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O77932"	"Decapping and exoribonuclease protein OS=Homo sapiens OX=9606 GN=DXO PE=2 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"396"	"44.9"	"7.69"	"344.54"	"4.14"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf08652"	"1797"	"ENSG00000204348; ENSG00000206346; ENSG00000224313; ENSG00000225682; ENSG00000234798; ENSG00000236765"	"DXO"	"A2CER3; B0UZ80; hsa:1797; O15004; O77932; O78127; O78128; Q5ST60; Q6IPZ2; Q9NPK4"	""	""	"0"	"0"	"16.0"	"18.6"	"25.7"	"37.6"	"26.3"	"23.4"	"44.2"	"46.3"	"50.1"	"124.5"	"174.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQ15"	"SOSS complex subunit B1 OS=Homo sapiens OX=9606 GN=NABP2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"211"	"22.3"	"9.06"	"393.98"	"4.13"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01336"	"79035"	"ENSG00000139579"	"NABP2"	"A6NDF8; hsa:79035; Q6XYC8; Q9BQ15"	"Mesodermal commitment pathway"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"48.6"	"26.4"	"71.3"	"71.5"	"48.0"	"64.7"	"67.5"	"70.4"	"70.4"	"131.8"	"260.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N999"	"Uncharacterized protein C12orf29 OS=Homo sapiens OX=9606 GN=C12orf29 PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"325"	"37.5"	"7.06"	""	"4.12"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	""	"other molecular function"	"Pf17720"	"91298"	"ENSG00000133641"	"RLIG1"	"hsa:91298; Q569K5; Q6AWA8; Q6PEK5; Q8IYQ5; Q8N999; Q9NT75"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z2E3"	"Aprataxin OS=Homo sapiens OX=9606 GN=APTX PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"356"	"40.7"	"9.17"	"429.57"	"4.11"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf11969, Pf16278, Pf17913"	"54840"	"ENSG00000137074"	"APTX"	"A8MTN4; D3DRK9; D3DRL0; hsa:54840; Q0P662; Q5T781; Q5T782; Q5T784; Q6JV81; Q6JV82; Q6JV85; Q7Z2E3; Q7Z2F3; Q7Z336; Q7Z5R5; Q7Z6V7; Q7Z6V8; Q9NXM5"	""	""	"0"	"0"	"49.2"	"49.7"	"49.5"	"64.9"	"43.5"	"43.8"	"84.0"	"97.3"	"130.3"	"313.4"	"467.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P16615"	"Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 OS=Homo sapiens OX=9606 GN=ATP2A2 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"1042"	"114.7"	"5.34"	""	"4.11"	""	"1"	"cell adhesion;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf00689, Pf00690, Pf08282, Pf13246"	"488"	"ENSG00000174437"	"ATP2A2"	"A6NDN7; B4DF05; hsa:488; P16614; P16615; Q86VJ2"	"Alzheimer's disease and miRNA effects; Arrhythmogenic right ventricular cardiomyopathy; Endothelin pathways; Myometrial relaxation and contraction pathways; Alzheimer's disease; Calcium regulation in cardiac cells"	"Ion homeostasis; Ion transport by P-type ATPases; Pre-NOTCH Processing in Golgi; Reduction of cytosolic Ca++ levels"	"10"	"0"	"36.4"	"33.7"	"35.8"	"46.0"	"23.5"	"34.1"	"39.4"	"45.7"	"61.0"	"153.6"	"203.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULX6"	"A-kinase anchor protein 8-like OS=Homo sapiens OX=9606 GN=AKAP8L PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"646"	"71.6"	"5.05"	"397.27"	"4.11"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"26993"	"ENSG00000011243"	"AKAP8L"	"B4DJ74; B5BU90; hsa:26993; O94792; Q96J58; Q9NRQ0; Q9UGM0; Q9ULX6"	""	"Formation of WDR5-containing histone-modifying complexes"	"1"	"0"	"45.2"	"45.7"	"57.2"	"73.8"	"49.2"	"63.3"	"96.1"	"108.2"	"148.6"	"384.7"	"592.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YM7"	"Homer protein homolog 1 OS=Homo sapiens OX=9606 GN=HOMER1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"354"	"40.3"	"5.44"	"383.26"	"4.11"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00568"	"9456"	"ENSG00000152413"	"HOMER1"	"B2R688; hsa:9456; O96003; Q86YM5; Q86YM7"	"BDNF-TrkB signaling; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Disruption of postsynaptic signaling by CNV; Orexin receptor pathway"	"Neurexins and neuroligins"	"6"	"0"	"31.3"	"34.2"	"39.0"	"55.4"	"46.5"	"42.6"	"63.6"	"61.8"	"89.0"	"148.5"	"204.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43824"	"Putative GTP-binding protein 6 OS=Homo sapiens OX=9606 GN=GTPBP6 PE=2 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"516"	"56.9"	"9.42"	"485.77"	"4.10"	"1"	"1"	""	"other cell component"	"translation activity;other molecular function"	"Pf01926, Pf13167, Pf16360"	"8225"	"ENSG00000178605"	"GTPBP6"	"H0Y2S1; hsa:8225; O43824; Q53F77; Q5HYX8"	""	""	"0"	"0"	"10.4"	"8.4"	"6.9"	"10.8"	"6.7"	"7.0"	"14.9"	"15.8"	"18.6"	"40.3"	"46.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P04181"	"Ornithine aminotransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OAT PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"439"	"48.5"	"7.03"	""	"4.09"	""	"1"	"other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00202"	"4942"	"ENSG00000065154"	"OAT"	"D3DRF0; hsa:4942; P04181; Q16068; Q16069; Q68CS0; Q6IAV9; Q9UD03"	"Amino acid metabolism; 22q11.2 copy number variation syndrome; Creatine pathway"	"Glutamate and glutamine metabolism"	"4"	"0"	"19.7"	"15.6"	"25.4"	"42.1"	"9.8"	"14.9"	"27.4"	"30.5"	"33.3"	"108.8"	"154.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HC52"	"Chromobox protein homolog 8 OS=Homo sapiens OX=9606 GN=CBX8 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"389"	"43.4"	"9.91"	"290.87"	"4.09"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"57332"	"ENSG00000141570"	"CBX8"	"hsa:57332; Q96H39; Q9HC52; Q9NR07"	""	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"8"	"0"	"47.3"	"40.4"	"54.6"	"60.2"	"49.3"	"50.2"	"72.3"	"85.5"	"100.2"	"241.1"	"375.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9C1"	"Spermatogenesis-defective protein 39 homolog OS=Homo sapiens OX=9606 GN=VIPAS39 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"493"	"57.0"	"7.40"	"349.63"	"4.09"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04840"	"63894"	"ENSG00000151445"	"VIPAS39"	"B4DPI6; hsa:63894; O95434; Q9H7E1; Q9H9C1; Q9H9I9"	""	""	"0"	"0"	"31.4"	"28.2"	"45.1"	"39.2"	"34.3"	"37.2"	"56.5"	"47.8"	"64.8"	"124.7"	"137.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7N4"	"Splicing factor, arginine/serine-rich 19 OS=Homo sapiens OX=9606 GN=SCAF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1312"	"139.2"	"9.25"	"342.26"	"4.09"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"58506"	"ENSG00000126461"	"SCAF1"	"hsa:58506; Q7Z5V7; Q8WVA1; Q9H7N4; Q9NR59"	""	""	"0"	"0"	"142.5"	"138.0"	"144.1"	"183.5"	"135.3"	"137.1"	"185.1"	"203.8"	"224.3"	"340.5"	"485.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13797"	"Plastin-3 OS=Homo sapiens OX=9606 GN=PLS3 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"630"	"70.8"	"5.60"	"401.45"	"4.08"	"1"	"1"	"cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf13499"	"5358"	"ENSG00000102024"	"PLS3"	"A8K579; B1AQ09; B4DGB4; B7Z6M1; hsa:5358; P13797; Q86YI6"	""	""	"0"	"0"	"48.4"	"39.9"	"67.1"	"169.2"	"36.9"	"29.4"	"69.8"	"87.5"	"98.9"	"316.7"	"394.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q63ZY3"	"KN motif and ankyrin repeat domain-containing protein 2 OS=Homo sapiens OX=9606 GN=KANK2 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"851"	"91.1"	"5.63"	""	"4.07"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"mitochondrion;other cell component"	""	"Pf12075, Pf12796"	"25959"	"ENSG00000197256"	"KANK2"	"B0I1P4; hsa:25959; Q3KQZ3; Q63ZY3; Q6GUF5; Q9H8S4; Q9NUP0; Q9P210"	""	""	"0"	"0"	"12.8"	"12.4"	"22.1"	"16.5"	"16.1"	"16.5"	"23.3"	"25.2"	"30.2"	"54.4"	"62.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q86WR0"	"Coiled-coil domain-containing protein 25 OS=Homo sapiens OX=9606 GN=CCDC25 PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"208"	"24.5"	"6.80"	""	"4.06"	""	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"nucleic acid binding activity"	"Pf05670"	"55246"	"ENSG00000147419"	"CCDC25"	"hsa:55246; Q0P663; Q86WR0; Q96SI2; Q9NV98"	""	""	"0"	"0"	"6.1"	"6.1"	"6.1"	"11.3"	"4.3"	"5.4"	"16.4"	"21.2"	"40.8"	"230.9"	"496.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUG6"	"p53 and DNA damage-regulated protein 1 OS=Homo sapiens OX=9606 GN=PDRG1 PE=1 SV=2"	"0.000"	""	"10"	"1"	"2"	"1"	"133"	"15.5"	"6.06"	"364.69"	"4.05"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf01920"	"81572"	"ENSG00000088356"	"PDRG1"	"B2R511; hsa:81572; Q96GP3; Q9BUW8; Q9NUG6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FK6"	"WD repeat-containing protein 89 OS=Homo sapiens OX=9606 GN=WDR89 PE=2 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"387"	"43.2"	"6.13"	"503.86"	"4.03"	"1"	"1"	"developmental processes"	""	""	"Pf00400"	"112840"	"ENSG00000140006"	"WDR89"	"hsa:112840; Q96FK6"	""	""	"0"	"0"	"16.3"	"18.2"	"26.4"	"30.6"	"21.0"	"20.3"	"43.7"	"42.3"	"68.2"	"363.0"	"392.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q12849"	"G-rich sequence factor 1 OS=Homo sapiens OX=9606 GN=GRSF1 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"480"	"53.1"	"6.19"	""	"4.03"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"2926"	"ENSG00000132463"	"GRSF1"	"B3KPW0; hsa:2926; Q12849; Q4W5S5; Q6ZST3; Q8IWD6; Q8NBD2"	"VEGFA-VEGFR2 signaling"	"Viral mRNA Translation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13685"	"Angio-associated migratory cell protein OS=Homo sapiens OX=9606 GN=AAMP PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"434"	"46.7"	"4.42"	""	"4.01"	""	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00400"	"14"	"ENSG00000127837"	"AAMP"	"hsa:14; Q13685; Q8WUJ9; Q96H92"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"NOD1/2 Signaling Pathway; Thromboxane signalling through TP receptor; Signaling by EGFR; Signaling by VEGF"	"5"	"0"	"17.5"	"13.3"	"17.9"	"17.1"	"17.9"	"16.2"	"25.7"	"19.5"	"31.2"	"77.0"	"142.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H223"	"EH domain-containing protein 4 OS=Homo sapiens OX=9606 GN=EHD4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"541"	"61.1"	"6.76"	"330.66"	"4.01"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00350, Pf12763, Pf16880, Pf18150"	"30844"	"ENSG00000103966"	"EHD4"	"hsa:30844; Q9H223; Q9HAR1; Q9NZN2"	""	""	"0"	"0"	"24.2"	"24.5"	"28.5"	"32.5"	"31.0"	"33.8"	"82.0"	"100.5"	"175.6"	"404.9"	"452.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43686"	"26S proteasome regulatory subunit 6B OS=Homo sapiens OX=9606 GN=PSMC4 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"418"	"47.3"	"5.21"	"390.81"	"4.01"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf16450, Pf17862"	"5704"	"ENSG00000013275; ENSG00000281221"	"PSMC4"	"hsa:5704; P43686; Q96FV5; Q9UBM3; Q9UEX3"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Regulation of RAS by GAPs; UCH proteinases; Ub-specific processing proteases; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Regulation of expression of SLITs and ROBOs; FCERI mediated NF-kB activation; Downstream TCR signaling; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; Orc1 removal from chromatin; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"64"	"0"	"37.7"	"37.1"	"45.3"	"48.4"	"36.6"	"43.0"	"66.7"	"72.9"	"98.9"	"245.6"	"417.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBK8"	"Methionine synthase reductase OS=Homo sapiens OX=9606 GN=MTRR PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"698"	"77.6"	"6.49"	"444.56"	"4.01"	"1"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"other molecular function"	"Pf00175, Pf00258, Pf00667"	"4552"	"ENSG00000124275"	"MTRR"	"hsa:4552; O60471; Q32MA9; Q7Z4M8; Q9UBK8"	"Vitamin B12 metabolism; Folate metabolism; One-carbon metabolism; Male infertility"	"Methylation; Cobalamin (Cbl) metabolism; Sulfur amino acid metabolism; Defective MTRR causes HMAE; Defective MTR causes HMAG"	"9"	"0"	"0.0"	"0.0"	"0.0"	"3.7"	"2.7"	"0.0"	"8.1"	"9.9"	"14.3"	"70.5"	"120.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H1A4"	"Anaphase-promoting complex subunit 1 OS=Homo sapiens OX=9606 GN=ANAPC1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1944"	"216.4"	"6.30"	"444.75"	"4.00"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf12859, Pf18122, Pf19521, Pf20518"	"64682"	"ENSG00000153107"	"ANAPC1"	"hsa:64682; Q2M3H8; Q9BSE6; Q9H1A4; Q9H8D0"	"Cell cycle; 2q13 copy number variation syndrome"	"Senescence-Associated Secretory Phenotype (SASP); Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"20"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P08183"	"ATP-dependent translocase ABCB1 OS=Homo sapiens OX=9606 GN=ABCB1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"1280"	"141.4"	"9.00"	""	"4.00"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"5243"	"ENSG00000085563"	"ABCB1"	"A8K294; B5AK60; hsa:5243; P08183; Q12755; Q14812"	"Codeine and morphine metabolism; Drug induction of bile acid pathway; Allograft rejection; Constitutive androstane receptor pathway; Pregnane X receptor pathway; Vitamin D receptor pathway; Nuclear receptors meta-pathway; Nuclear receptors in lipid metabolism and toxicity; Imatinib and chronic myeloid leukemia; lncRNA-mediated mechanisms of therapeutic resistance; Male infertility; Proximal tubule transport"	"ABC-family proteins mediated transport; Abacavir transmembrane transport; Prednisone ADME; Atorvastatin ADME"	"16"	"0"	"42.9"	"45.3"	"59.8"	"69.4"	"52.0"	"44.2"	"70.9"	"52.6"	"57.0"	"99.8"	"145.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVS5"	"tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=TRMT61B PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"477"	"52.9"	"6.62"	"405.57"	"4.00"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf08704"	"55006"	"ENSG00000171103"	"TRMT61B"	"hsa:55006; Q9BVS5; Q9H0Q9; Q9NWS7"	""	"tRNA modification in the mitochondrion"	"1"	"0"	"13.5"	"5.4"	"11.0"	"12.8"	"9.1"	"13.7"	"17.3"	"17.6"	"28.5"	"68.6"	"115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00743"	"Serine/threonine-protein phosphatase 6 catalytic subunit OS=Homo sapiens OX=9606 GN=PPP6C PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"305"	"35.1"	"5.69"	"335.15"	"4.00"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00149"	"5537"	"ENSG00000119414"	"PPP6C"	"B2R5V6; B7Z2W9; B7Z5K9; hsa:5537; O00743; Q5U0A2; Q9UIC9"	""	"Telomere Extension By Telomerase; COPII-mediated vesicle transport"	"2"	"0"	"98.3"	"22.1"	"78.1"	"57.2"	"58.3"	"46.9"	"82.4"	"63.1"	"84.4"	"191.8"	"287.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27144"	"Adenylate kinase 4, mitochondrial OS=Homo sapiens OX=9606 GN=AK4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"223"	"25.3"	"8.40"	"340.53"	"4.00"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"205"	"ENSG00000162433"	"AK4"	"B2R927; D3DQ62; hsa:205; P27144; Q6IBH4; Q6NXQ5; Q8IUU9"	"CCL18 signaling pathway"	"Interconversion of nucleotide di- and triphosphates"	"2"	"0"	"13.5"	"4.9"	"18.1"	"19.0"	"8.1"	"19.2"	"28.0"	"31.5"	"78.5"	"349.3"	"677.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIJ7"	"GTP:AMP phosphotransferase AK3, mitochondrial OS=Homo sapiens OX=9606 GN=AK3 PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"227"	"25.6"	"9.16"	"392.01"	"4.00"	"1"	"1"	"other metabolic processes;stress response"	"mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00406, Pf05191"	"50808"	"ENSG00000147853"	"AK3"	"B4DP58; D3DRI1; E7ET30; hsa:50808; Q5VYW6; Q9H576; Q9HC01; Q9NPB4; Q9UIJ7"	""	"Factors involved in megakaryocyte development and platelet production"	"1"	"0"	"10.8"	"12.0"	"12.6"	"15.6"	"11.4"	"10.7"	"15.5"	"20.0"	"31.0"	"75.6"	"166.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96Q83"	"Alpha-ketoglutarate-dependent dioxygenase alkB homolog 3 OS=Homo sapiens OX=9606 GN=ALKBH3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"286"	"33.4"	"8.40"	"280.94"	"3.99"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf13532"	"221120"	"ENSG00000166199"	"ALKBH3"	"A6NDJ1; hsa:221120; Q3SYI0; Q6NX57; Q96BU8; Q96Q83"	"Direct reversal repair; 11p11.2 copy number variation syndrome"	"ALKBH3 mediated reversal of alkylation damage"	"3"	"0"	"29.9"	"25.2"	"27.5"	"31.4"	"31.0"	"26.7"	"47.6"	"48.0"	"64.4"	"116.2"	"195.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVL6"	"Prolyl 3-hydroxylase 3 OS=Homo sapiens OX=9606 GN=P3H3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"736"	"81.8"	"6.32"	"399.61"	"3.99"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf13640"	"10536"	"ENSG00000110811"	"P3H3"	"hsa:10536; Q13512; Q15740; Q66K32; Q6NX61; Q7L2T1; Q8IVL6"	""	"Collagen biosynthesis and modifying enzymes"	"1"	"0"	"12.9"	"12.2"	"20.1"	"15.2"	"10.6"	"4.5"	"21.5"	"14.4"	"21.8"	"38.5"	"49.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96F85"	"CB1 cannabinoid receptor-interacting protein 1 OS=Homo sapiens OX=9606 GN=CNRIP1 PE=1 SV=1"	""	""	"13"	"1"	"1"	"1"	"164"	"18.6"	"7.94"	""	"3.99"	""	"1"	"other biological processes"	"plasma membrane;other membranes;other cell component"	"signal transduction activity or receptor binding"	"Pf15043"	"25927"	"ENSG00000119865"	"CNRIP1"	"B2R4D0; hsa:25927; Q49AN4; Q96F85; Q9UFZ0"	""	""	"0"	"0"	"5.0"	"9.7"	"18.3"	"22.0"	"33.0"	"67.1"	"125.4"	"130.7"	"167.4"	"207.4"	"199.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NT62"	"Ubiquitin-like-conjugating enzyme ATG3 OS=Homo sapiens OX=9606 GN=ATG3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"314"	"35.8"	"4.74"	"326.97"	"3.99"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf03987"	"64422"	"ENSG00000144848"	"ATG3"	"hsa:64422; Q6PKC5; Q9H6L9; Q9NT62"	"Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; Clock-controlled autophagy in bone metabolism"	"Macroautophagy"	"5"	"0"	"25.2"	"31.8"	"28.1"	"34.0"	"29.3"	"29.2"	"43.7"	"38.0"	"52.9"	"102.5"	"127.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZYL4"	"General transcription factor IIH subunit 5 OS=Homo sapiens OX=9606 GN=GTF2H5 PE=1 SV=1"	"0.000"	""	"21"	"1"	"2"	"1"	"71"	"8.0"	"4.65"	"408.21"	"3.98"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf06331"	"404672"	"ENSG00000272047"	"GTF2H5"	"hsa:404672; Q0P5V8; Q6ZYL4"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; TP53 Regulates Transcription of DNA Repair Genes; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"32"	"0"	"21.5"	"17.9"	"25.1"	"29.6"	"16.6"	"18.0"	"67.3"	"71.4"	"91.5"	"133.1"	"138.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94880"	"PHD finger protein 14 OS=Homo sapiens OX=9606 GN=PHF14 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"888"	"100.0"	"5.33"	"387.17"	"3.98"	"1"	"1"	""	""	"other molecular function"	"Pf00628, Pf13832"	"463265"	"ENSPTRG00000018935"	"PHF14"	"A0A2J8MED2; A0A6D2XU20; H2RCM0; ptr:463265"	""	""	"0"	"0"	"15.2"	"22.1"	"20.8"	"19.9"	"14.6"	"15.0"	"27.1"	"26.1"	"28.6"	"58.6"	"72.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q969T4"	"Ubiquitin-conjugating enzyme E2 E3 OS=Homo sapiens OX=9606 GN=UBE2E3 PE=1 SV=1"	""	""	"19"	"1"	"1"	"1"	"207"	"22.9"	"7.18"	""	"3.98"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"10477"	"ENSG00000170035"	"UBE2E3"	"B2RAD6; D3DPG3; hsa:10477; Q5U0R7; Q7Z4W4; Q969T4"	"7q11.23 copy number variation syndrome"	"Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4K4"	"Mitogen-activated protein kinase kinase kinase kinase 5 OS=Homo sapiens OX=9606 GN=MAP4K5 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"846"	"95.0"	"7.83"	"482.25"	"3.98"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"plasma membrane;other membranes;cytosol;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00780"	"11183"	"ENSG00000012983"	"MAP4K5"	"A0A0A0MQR1; hsa:11183; Q8IYF6; Q9Y4K4"	"Angiopoietin-like protein 8 regulatory pathway; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Insulin signaling"	""	"3"	"0"	"50.8"	"45.1"	"47.0"	"50.4"	"42.6"	"42.5"	"60.7"	"62.4"	"71.4"	"130.7"	"180.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVX9"	"Fatty acyl-CoA reductase 1 OS=Homo sapiens OX=9606 GN=FAR1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"515"	"59.3"	"9.17"	"440.11"	"3.96"	"1"	"1"	"other metabolic processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf03015, Pf07993"	"84188"	"ENSG00000197601"	"FAR1"	"D3DQW8; hsa:84188; Q5CZA3; Q8WVX9"	""	"Wax biosynthesis"	"1"	"0"	"19.4"	"26.3"	"10.8"	"29.9"	"13.2"	"13.5"	"39.4"	"41.2"	"61.0"	"190.3"	"232.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EH3"	"Mitochondrial assembly of ribosomal large subunit protein 1 OS=Homo sapiens OX=9606 GN=MALSU1 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"234"	"26.2"	"5.49"	"439.44"	"3.96"	"1"	"1"	"other biological processes"	"cytosol;mitochondrion"	"translation activity"	"Pf02410"	"115416"	"ENSG00000156928"	"MALSU1"	"A4D154; hsa:115416; Q96EH3"	""	""	"0"	"0"	"7.6"	"6.2"	"10.6"	"12.2"	"8.8"	"4.4"	"28.6"	"27.6"	"49.1"	"195.2"	"325.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H9J2"	"39S ribosomal protein L44, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL44 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"332"	"37.5"	"8.40"	"1130.15"	"3.96"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"plasma membrane;other membranes;mitochondrion;translational apparatus;nucleus"	"nucleic acid binding activity;other molecular function"	""	"65080"	"ENSG00000135900"	"MRPL44"	"hsa:65080; Q53S16; Q6IA62; Q9H821; Q9H9J2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"77.9"	"69.2"	"85.4"	"93.1"	"76.2"	"77.5"	"111.2"	"118.7"	"174.9"	"333.0"	"526.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51532"	"Transcription activator BRG1 OS=Homo sapiens OX=9606 GN=SMARCA4 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1647"	"184.5"	"7.88"	"388.32"	"3.95"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00439, Pf07529, Pf07533, Pf08880, Pf14619"	"6597"	"ENSG00000127616"	"SMARCA4"	"B1A8Z4; B1A8Z5; B1A8Z6; B1A8Z7; E9PBR8; hsa:6597; O95052; P51532; Q9HBD3"	"Androgen receptor network in prostate cancer; Pre-implantation embryo; Hematopoietic stem cell gene regulation by GABP alpha/beta complex; Tumor suppressor activity of SMARCB1; Rett syndrome causing genes; Thermogenesis; Kleefstra syndrome"	"Formation of the beta-catenin:TCF transactivating complex; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Interleukin-7 signaling; RMTs methylate histone arginines; EGR2 and SOX10-mediated initiation of Schwann cell myelination"	"13"	"0"	"34.6"	"31.9"	"55.3"	"61.0"	"36.1"	"42.8"	"53.9"	"53.7"	"65.2"	"157.4"	"213.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P49902"	"Cytosolic purine 5'-nucleotidase OS=Homo sapiens OX=9606 GN=NT5C2 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"561"	"64.9"	"6.14"	""	"3.95"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"kinase activity;other molecular function"	"Pf05761"	"22978"	"ENSG00000076685"	"NT5C2"	"B7Z382; D3DR91; hsa:22978; P49902; Q5JUV5"	""	"Purine catabolism; Ribavirin ADME; Abacavir metabolism"	"3"	"0"	"0.0"	"0.0"	"0.0"	"4.8"	"3.6"	"0.0"	"5.9"	"7.4"	"14.6"	"46.3"	"75.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RL1"	"BRCA1-A complex subunit RAP80 OS=Homo sapiens OX=9606 GN=UIMC1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"719"	"79.7"	"5.45"	"378.00"	"3.95"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf18282"	"51720"	"ENSG00000087206"	"UIMC1"	"A8MSA1; B3KMZ1; B4E3N2; hsa:51720; Q5XKQ1; Q7Z3W7; Q8N5B9; Q96RL1; Q9BZR1; Q9BZR5; Q9UHX7"	"5q35 copy number variation"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ); Metalloprotease DUBs"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38606"	"V-type proton ATPase catalytic subunit A OS=Homo sapiens OX=9606 GN=ATP6V1A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"617"	"68.3"	"5.52"	"372.97"	"3.95"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00006, Pf02874, Pf16886"	"523"	"ENSG00000114573"	"ATP6V1A"	"B2RBR8; B7Z1R5; D3DN75; hsa:523; P38606; Q53YD9; Q96DY6; Q9UHY3"	"Proximal tubule transport"	"Amino acids regulate mTORC1; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"6"	"0"	"10.4"	"6.9"	"11.4"	"10.9"	"6.4"	"6.7"	"16.6"	"20.2"	"24.4"	"69.5"	"90.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6Y7W6"	"GRB10-interacting GYF protein 2 OS=Homo sapiens OX=9606 GN=GIGYF2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1299"	"150.0"	"5.54"	"475.69"	"3.94"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf02213"	"26058"	"ENSG00000204120"	"GIGYF2"	"A6H8W4; B9EG55; E9PBB0; hsa:26058; O75137; Q6Y7W6; Q7Z2Z8; Q7Z3I2; Q96HU4; Q9NV82"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"25.4"	"18.9"	"23.7"	"30.3"	"28.7"	"27.7"	"35.7"	"32.8"	"34.7"	"93.7"	"122.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30084"	"Enoyl-CoA hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ECHS1 PE=1 SV=4"	"0.000"	""	"6"	"1"	"2"	"1"	"290"	"31.4"	"8.07"	"534.78"	"3.94"	"1"	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00378"	"1892"	"ENSG00000127884"	"ECHS1"	"hsa:1892; O00739; P30084; Q5VWY1; Q96H54"	"Fatty acid beta-oxidation; Fatty acid biosynthesis; Ciliary landscape; Tryptophan metabolism"	"Branched-chain amino acid catabolism; Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA; Beta oxidation of octanoyl-CoA to hexanoyl-CoA; Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA; Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA"	"10"	"0"	"24.0"	"20.4"	"37.2"	"42.4"	"18.7"	"16.0"	"38.0"	"36.3"	"40.6"	"85.9"	"109.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60341"	"Lysine-specific histone demethylase 1A OS=Homo sapiens OX=9606 GN=KDM1A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"852"	"92.8"	"6.52"	"314.14"	"3.94"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01593, Pf04433"	"23028"	"ENSG00000004487"	"KDM1A"	"A8MWP9; hsa:23028; O60341; Q5TH94; Q5TH95; Q86VT7; Q8IXK4; Q8NDP6; Q8TAZ3; Q96AW4"	"Androgen receptor signaling pathway; Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome; Thermogenesis; Vitamin D-sensitive calcium signaling in depression; Thyroid hormones production and peripheral downstream signaling effects; Neurogenesis regulation in the olfactory epithelium"	"Estrogen-dependent gene expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Factors involved in megakaryocyte development and platelet production; HDMs demethylate histones; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3"	"14"	"0"	"18.9"	"21.1"	"23.1"	"40.7"	"21.6"	"20.3"	"41.0"	"36.1"	"54.5"	"241.6"	"450.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HD47"	"Ran guanine nucleotide release factor OS=Homo sapiens OX=9606 GN=RANGRF PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"186"	"20.4"	"4.94"	"413.20"	"3.94"	"1"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04603"	"29098"	"ENSG00000108961"	"RANGRF"	"D3DTR6; hsa:29098; Q68DI3; Q9BR68; Q9HD47; Q9HD48; Q9NRU9; Q9P001; Q9P0P2"	""	"Phase 0 - rapid depolarisation"	"1"	"0"	"12.6"	"8.7"	"12.4"	"15.8"	"11.4"	"12.5"	"15.8"	"16.1"	"22.4"	"33.2"	"29.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35914"	"Hydroxymethylglutaryl-CoA lyase, mitochondrial OS=Homo sapiens OX=9606 GN=HMGCL PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"325"	"34.3"	"8.54"	"371.92"	"3.94"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00682"	"3155"	"ENSG00000117305"	"HMGCL"	"B4DUP4; B7UCC6; D3Y5K7; hsa:3155; P35914; Q6IBC0; Q96FP8"	"Amino acid metabolism"	"Peroxisomal protein import; Synthesis of Ketone Bodies"	"3"	"0"	"48.0"	"32.2"	"50.1"	"60.8"	"38.4"	"40.9"	"65.1"	"87.9"	"99.0"	"224.5"	"303.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48047"	"ATP synthase subunit O, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PO PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"213"	"23.3"	"9.96"	"469.11"	"3.93"	"1"	"1"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00213"	"539"	"ENSG00000241837"	"ATP5PO"	"B2R4E2; hsa:539; P48047; Q5U042; Q6IBI2"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"51.0"	"45.8"	"49.5"	"62.9"	"42.4"	"41.2"	"92.4"	"91.5"	"140.6"	"263.9"	"292.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P20936"	"Ras GTPase-activating protein 1 OS=Homo sapiens OX=9606 GN=RASA1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1047"	"116.3"	"6.54"	"366.16"	"3.93"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00169, Pf00616"	"5921"	"ENSG00000145715"	"RASA1"	"B2R6W3; B4DTL2; hsa:5921; P20936; Q68CU6; Q9UDI1"	"Androgen receptor network in prostate cancer; PDGF pathway; T cell receptor and co-stimulatory signaling; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; MAPK signaling pathway; Ras signaling; Acute viral myocarditis; EGF/EGFR signaling pathway; GDNF signaling; EPO receptor signaling"	"Downstream signal transduction; Regulation of RAS by GAPs; EPHB-mediated forward signaling; VEGFR2 mediated cell proliferation; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"16"	"0"	"4.7"	"4.4"	"9.6"	"8.3"	"6.5"	"6.6"	"73.7"	"89.6"	"208.0"	"999.5"	"1430.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55060"	"Exportin-2 OS=Homo sapiens OX=9606 GN=CSE1L PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"971"	"110.3"	"5.77"	"379.43"	"3.92"	"1"	"1"	"transport"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03378, Pf03810, Pf08506"	"1434"	"ENSG00000124207"	"CSE1L"	"A3RLL6; B2R5T4; E1P5Y0; F8W904; hsa:1434; O75432; P55060; Q32M40; Q9H5B7; Q9NTS0; Q9UP98; Q9UP99; Q9UPA0"	""	""	"0"	"0"	"29.3"	"20.9"	"39.6"	"30.0"	"19.8"	"21.9"	"51.9"	"36.4"	"66.5"	"203.8"	"364.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N300"	"Small vasohibin-binding protein OS=Homo sapiens OX=9606 GN=SVBP PE=1 SV=1"	"0.000"	""	"35"	"2"	"3"	"2"	"66"	"7.8"	"9.16"	"598.99"	"3.92"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;transport;developmental processes;other biological processes"	"non-structural extracellular;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf15674"	"374969"	"ENSG00000177868"	"SVBP"	"A8K5P1; D3DPW7; hsa:374969; Q8N300"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	"112.2"	"93.5"	"153.4"	"174.9"	"115.4"	"126.7"	"266.9"	"297.2"	"359.6"	"730.0"	"949.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78316"	"Nucleolar protein 14 OS=Homo sapiens OX=9606 GN=NOP14 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"857"	"97.6"	"7.58"	"561.82"	"3.92"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04147"	"8602"	"ENSG00000087269"	"NOP14"	"D3DVR6; hsa:8602; P78316; Q7LGI5; Q7Z6K0; Q8TBR6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"70.4"	"46.3"	"76.0"	"72.8"	"68.3"	"57.8"	"97.3"	"82.8"	"116.5"	"154.1"	"211.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37198"	"Nuclear pore glycoprotein p62 OS=Homo sapiens OX=9606 GN=NUP62 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"2"	"522"	"53.2"	"5.31"	"699.79"	"3.91"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"other membranes;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05064"	"23636"	"ENSG00000213024"	"NUP62"	"B3KWU5; hsa:23636; P37198; Q503A4; Q6GTM2; Q96C43; Q9NSL1"	"7q11.23 copy number variation syndrome"	"Regulation of HSF1-mediated heat shock response; Nuclear Pore Complex (NPC) Disassembly; HCMV Early Events; HCMV Late Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"30"	"0"	"221.1"	"171.3"	"234.9"	"287.5"	"174.5"	"199.3"	"295.3"	"280.4"	"301.9"	"612.4"	"843.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYV4"	"Cyclin-dependent kinase 12 OS=Homo sapiens OX=9606 GN=CDK12 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1490"	"164.1"	"9.44"	"292.56"	"3.91"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"51755"	"ENSG00000167258"	"CDK12"	"A7E2B2; B4DYX4; B9EIQ6; hsa:51755; O94978; Q9NYV4"	"17q12 copy number variation syndrome"	"TP53 Regulates Transcription of DNA Repair Genes"	"2"	"0"	"40.1"	"37.6"	"56.4"	"65.4"	"40.3"	"35.2"	"57.4"	"61.6"	"82.6"	"160.7"	"243.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22695"	"Cytochrome b-c1 complex subunit 2, mitochondrial OS=Homo sapiens OX=9606 GN=UQCRC2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"453"	"48.4"	"8.63"	"398.02"	"3.91"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00675, Pf05193"	"7385"	"ENSG00000140740"	"UQCRC2"	"B3KSN4; hsa:7385; P22695; Q9BQ05"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex III assembly"	"Respiratory electron transport"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4J0"	"Carnosine N-methyltransferase OS=Homo sapiens OX=9606 GN=CARNMT1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"409"	"47.2"	"6.32"	"461.54"	"3.91"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf07942"	"138199"	"ENSG00000156017"	"CARNMT1"	"hsa:138199; Q7Z383; Q8N4J0; Q8N7C5"	""	"Histidine catabolism"	"1"	"0"	"14.0"	"8.8"	"16.7"	"22.1"	"14.4"	"16.0"	"28.1"	"24.2"	"40.0"	"123.5"	"154.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYB7"	"DIS3-like exonuclease 2 OS=Homo sapiens OX=9606 GN=DIS3L2 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"885"	"99.2"	"6.10"	"366.26"	"3.90"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00773, Pf17216, Pf17849, Pf17877"	"129563"	"ENSG00000144535"	"DIS3L2"	"hsa:129563; Q53S79; Q580W6; Q5XKH0; Q69YG5; Q6AW99; Q7Z4T6; Q8IYB7; Q8N9K9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14579"	"Coatomer subunit epsilon OS=Homo sapiens OX=9606 GN=COPE PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"308"	"34.5"	"5.12"	"351.59"	"3.90"	"1"	"1"	"transport;other biological processes"	"other membranes;cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf04733"	"11316"	"ENSG00000105669"	"COPE"	"A6NE29; A6NKA3; hsa:11316; O14579; O76097; Q6IBB8; Q9UGP6"	""	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport"	"2"	"0"	"11.3"	"16.7"	"18.3"	"24.0"	"17.5"	"17.4"	"40.7"	"40.1"	"68.0"	"253.5"	"359.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q02978"	"Mitochondrial 2-oxoglutarate/malate carrier protein OS=Homo sapiens OX=9606 GN=SLC25A11 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"314"	"34.0"	"9.91"	"461.63"	"3.90"	"1"	"1"	"other metabolic processes;transport"	"plasma membrane;other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"8402"	"ENSG00000108528"	"SLC25A11"	"F5GY65; hsa:8402; O75537; Q02978; Q969P7"	"VEGFA-VEGFR2 signaling"	"Gluconeogenesis"	"2"	"0"	"6.6"	"3.0"	"8.0"	"11.1"	"4.0"	"5.3"	"13.9"	"17.4"	"30.2"	"89.5"	"144.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H583"	"HEAT repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=HEATR1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2144"	"242.2"	"6.54"	"483.52"	"3.89"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf08146, Pf12397"	"55127"	"ENSG00000119285"	"HEATR1"	"hsa:55127; Q5T3Q8; Q6P197; Q9H583; Q9NW23"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"29.2"	"26.7"	"31.1"	"41.7"	"24.4"	"30.8"	"52.9"	"52.1"	"97.3"	"191.2"	"202.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4U2R6"	"39S ribosomal protein L51, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL51 PE=1 SV=1"	"0.000"	""	"9"	"1"	"3"	"1"	"128"	"15.1"	"11.27"	"862.62"	"3.88"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10244"	"51258"	"ENSG00000111639"	"MRPL51"	"hsa:51258; Q4U2R6; Q96Q57; Q9BQ36; Q9P0N7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"68.0"	"74.8"	"102.3"	"113.0"	"87.4"	"71.7"	"122.8"	"141.9"	"166.5"	"340.4"	"624.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46199"	"Translation initiation factor IF-2, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"727"	"81.3"	"7.15"	"409.27"	"3.87"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00009, Pf11987"	"4528"	"ENSG00000085760"	"MTIF2"	"D6W5D0; hsa:4528; P46199"	""	"Mitochondrial translation initiation"	"1"	"0"	"22.6"	"16.4"	"26.3"	"36.2"	"24.9"	"27.0"	"54.5"	"54.6"	"84.7"	"206.3"	"249.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75347"	"Tubulin-specific chaperone A OS=Homo sapiens OX=9606 GN=TBCA PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"108"	"12.8"	"5.29"	"499.77"	"3.87"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02970"	"6902"	"ENSG00000171530"	"TBCA"	"B4DT30; hsa:6902; O75347"	"VEGFA-VEGFR2 signaling"	"Post-chaperonin tubulin folding pathway"	"2"	"0"	"28.5"	"40.2"	"42.6"	"80.8"	"23.7"	"27.0"	"50.1"	"53.4"	"63.9"	"233.1"	"414.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P587"	"Acylpyruvase FAHD1, mitochondrial OS=Homo sapiens OX=9606 GN=FAHD1 PE=1 SV=2"	"0.000"	""	"6"	"1"	"2"	"1"	"224"	"24.8"	"7.39"	"378.10"	"3.87"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf01557"	"81889"	"ENSG00000180185"	"FAHD1"	"B1AK40; B1AK41; hsa:81889; Q6FIC7; Q6P587; Q96RY1; Q9H0N6"	""	"Citric acid cycle (TCA cycle)"	"1"	"0"	"27.5"	"28.9"	"30.8"	"35.8"	"31.0"	"36.3"	"68.4"	"76.3"	"135.3"	"363.5"	"628.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQW6"	"Anillin OS=Homo sapiens OX=9606 GN=ANLN PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"1124"	"124.1"	"8.07"	"395.18"	"3.86"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00169, Pf08174, Pf16018"	"54443"	"ENSG00000011426"	"ANLN"	"hsa:54443; Q5CZ78; Q6NSK5; Q9H8Y4; Q9NQW6; Q9NVN9; Q9NVP0"	"Retinoblastoma gene in cancer; Nephrotic syndrome"	"RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"5"	"0"	"19.1"	"14.0"	"15.7"	"17.5"	"15.8"	"15.2"	"40.2"	"44.1"	"102.2"	"187.9"	"193.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75947"	"ATP synthase subunit d, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5PD PE=1 SV=3"	"0.000"	""	"11"	"1"	"2"	"1"	"161"	"18.5"	"5.30"	"323.96"	"3.86"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05873"	"10476"	"ENSG00000167863"	"ATP5PD"	"B2R5L6; hsa:10476; O75947; Q9H3J4"	"Electron transport chain: OXPHOS system in mitochondria; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"4"	"0"	"16.7"	"19.4"	"23.9"	"27.9"	"17.2"	"12.4"	"32.0"	"33.5"	"48.9"	"146.1"	"194.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2M7"	"Cingulin OS=Homo sapiens OX=9606 GN=CGN PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1197"	"136.3"	"5.54"	"521.17"	"3.86"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"26.1"	"20.6"	"40.7"	"41.2"	"25.1"	"29.6"	"42.4"	"39.9"	"46.2"	"100.2"	"136.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15004"	"PCNA-associated factor OS=Homo sapiens OX=9606 GN=PCLAF PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"111"	"12.0"	"9.83"	"344.71"	"3.86"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15715"	"9768"	"ENSG00000166803"	"PCLAF"	"A6NNU5; A8K3Y3; G9G694; G9G696; hsa:9768; Q15004"	""	"Termination of translesion DNA synthesis"	"1"	"0"	"50.8"	"41.6"	"50.8"	"53.3"	"40.5"	"33.1"	"58.9"	"53.1"	"84.7"	"117.5"	"134.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZN5"	"Rho guanine nucleotide exchange factor 12 OS=Homo sapiens OX=9606 GN=ARHGEF12 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1544"	"173.1"	"5.74"	"387.08"	"3.85"	"1"	"1"	"signal transduction;other biological processes"	"other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity"	"Pf00595, Pf00621, Pf09128, Pf17838"	"23365"	"ENSG00000196914"	"ARHGEF12"	"hsa:23365; O15086; Q6P526; Q9NZN5"	"Netrin-UNC5B signaling pathway"	"RHOC GTPase cycle; G alpha (12/13) signalling events; Sema4D induced cell migration and growth-cone collapse; RHOA GTPase cycle; CDC42 GTPase cycle; NRAGE signals death through JNK; RHOB GTPase cycle"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H444"	"Charged multivesicular body protein 4b OS=Homo sapiens OX=9606 GN=CHMP4B PE=1 SV=1"	"0.000"	""	"12"	"3"	"4"	"3"	"224"	"24.9"	"4.82"	"936.15"	"3.85"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"128866"	"ENSG00000101421"	"CHMP4B"	"E1P5N4; hsa:128866; Q53ZD6; Q9H444"	""	"Sealing of the nuclear envelope (NE) by ESCRT-III; Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Late endosomal microautophagy; Macroautophagy; Pyroptosis; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"9"	"0"	"347.8"	"226.2"	"438.5"	"570.6"	"371.8"	"362.3"	"477.2"	"503.7"	"583.9"	"960.6"	"2080.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13131"	"5'-AMP-activated protein kinase catalytic subunit alpha-1 OS=Homo sapiens OX=9606 GN=PRKAA1 PE=1 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"559"	"64.0"	"8.12"	"534.85"	"3.85"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf16579"	"5562"	"ENSG00000132356"	"PRKAA1"	"A8MTQ6; B2R7E1; hsa:5562; O00286; Q13131; Q5D0E1; Q86VS1; Q9UNQ4"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Thyroxine (thyroid hormone) production; Sterol regulatory element-binding proteins (SREBP) signaling; SREBF and miR33 in cholesterol and lipid homeostasis; Leptin signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; mir-124 predicted interactions with cell cycle and differentiation ; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Leptin and adiponectin; Lipid metabolism pathway; PI3K-Akt signaling pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Head and neck squamous cell carcinoma; IL-18 signaling pathway; Insulin signaling; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; Pleural mesothelioma; Disturbed pathways in Duchenne Muscular Dystrophy"	"Activation of AMPK downstream of NMDARs; Regulation of TP53 Activity through Phosphorylation; TP53 Regulates Metabolic Genes; Macroautophagy; Energy dependent regulation of mTOR by LKB1-AMPK"	"35"	"0"	"13.2"	"11.4"	"15.8"	"17.2"	"9.0"	"7.8"	"34.7"	"39.2"	"82.0"	"262.8"	"425.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43670"	"BUB3-interacting and GLEBS motif-containing protein ZNF207 OS=Homo sapiens OX=9606 GN=ZNF207 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"478"	"50.7"	"9.10"	"500.30"	"3.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	""	"7756"	"ENSG00000010244"	"ZNF207"	"A8K6Y6; E1P660; E1P661; E1P662; hsa:7756; O43670; Q53XS9; Q96HW5; Q9BUQ7"	""	""	"0"	"0"	"46.7"	"49.0"	"50.7"	"63.2"	"42.8"	"42.9"	"56.6"	"66.8"	"93.2"	"163.3"	"217.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UGM6"	"Tryptophan--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=WARS2 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"360"	"40.1"	"9.28"	"690.83"	"3.84"	"2"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf00579"	"10352"	"ENSG00000116874"	"WARS2"	"B1ALR1; B2R9D4; hsa:10352; Q53FT4; Q5VUD2; Q86TQ0; Q9UGM6"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"15.3"	"12.9"	"24.3"	"33.0"	"20.8"	"17.9"	"54.2"	"70.9"	"132.4"	"454.5"	"504.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46379"	"Large proline-rich protein BAG6 OS=Homo sapiens OX=9606 GN=BAG6 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1132"	"119.3"	"5.60"	"343.94"	"3.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;translation activity;other molecular function"	"Pf00240, Pf12057"	"7917"	"ENSG00000096155; ENSG00000204463; ENSG00000227761; ENSG00000228760; ENSG00000229524; ENSG00000233348; ENSG00000234651"	"BAG6"	"A2ADJ7; A3KQ42; A3KQ44; A6NGY6; A6PWF7; B0UX84; B4DZ12; B4E3V4; E7EMZ4; F8VXY4; hsa:7917; O95874; P46379; Q5HYL9; Q5SQ35; Q5SQ36; Q5SQ37; Q5SQ41; Q5SRP8; Q5SRP9; Q5STC1; Q5STX1; Q5STX3; Q96SA6; Q9BCN4"	""	"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"1"	"0"	"11.3"	"10.4"	"14.5"	"16.5"	"11.6"	"13.3"	"19.6"	"23.4"	"31.2"	"94.2"	"156.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62891"	"60S ribosomal protein L39 OS=Homo sapiens OX=9606 GN=RPL39 PE=1 SV=2"	"0.000"	""	"20"	"1"	"2"	"1"	"51"	"6.4"	"12.56"	"362.07"	"3.84"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"non-structural extracellular;cytosol;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf00832"	"6170"	"ENSG00000198918"	"RPL39"	"hsa:6170; P02404; P39025; P62891; Q9BYF2"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"144.7"	"106.9"	"173.1"	"191.9"	"156.5"	"153.7"	"191.8"	"197.2"	"215.3"	"331.8"	"515.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51946"	"Cyclin-H OS=Homo sapiens OX=9606 GN=CCNH PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"323"	"37.6"	"7.15"	"341.33"	"3.83"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"enzyme regulator activity"	"Pf00134, Pf16899"	"902"	"ENSG00000134480"	"CCNH"	"hsa:902; P51946; Q53X72; Q8TBL9"	"Cell cycle; Eukaryotic transcription initiation; G1 to S cell cycle control; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; Cyclin D associated events in G1; Cyclin A/B1/B2 associated events during G2/M transition; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Formation of Incision Complex in GG-NER; Cyclin E associated events during G1/S transition ; Cyclin A:Cdk2-associated events at S phase entry"	"39"	"0"	"15.0"	"9.3"	"14.0"	"24.4"	"15.5"	"14.1"	"64.5"	"58.7"	"127.4"	"341.1"	"607.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVM0"	"Coiled-coil domain-containing protein 50 OS=Homo sapiens OX=9606 GN=CCDC50 PE=1 SV=1"	"0.000"	""	"12"	"3"	"4"	"3"	"306"	"35.8"	"6.65"	"1408.70"	"3.82"	"3"	"1"	"other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf15295"	"152137"	"ENSG00000152492"	"CCDC50"	"hsa:152137; Q86VH7; Q8IVM0"	""	""	"0"	"0"	"208.3"	"203.1"	"238.5"	"241.8"	"179.0"	"190.5"	"448.5"	"466.0"	"746.9"	"1359.4"	"1519.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZK7"	"F-box-like/WD repeat-containing protein TBL1XR1 OS=Homo sapiens OX=9606 GN=TBL1XR1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"514"	"55.6"	"5.55"	"486.15"	"3.81"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00400, Pf08513"	"79718"	"ENSG00000177565"	"TBL1XR1"	"D3DNQ9; hsa:79718; Q14DC3; Q9BZK7; Q9H2I1; Q9H9A1"	"Rett syndrome causing genes"	"Heme signaling; Transcriptional activation of mitochondrial biogenesis; HCMV Early Events; HDACs deacetylate histones; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH1 Intracellular Domain Regulates Transcription; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Cytoprotection by HMOX1; Activation of gene expression by SREBF (SREBP); Notch-HLH transcription pathway; Loss of MECP2 binding ability to the NCoR/SMRT complex; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; RORA activates gene expression"	"20"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06481"	"Amyloid-like protein 2 OS=Homo sapiens OX=9606 GN=APLP2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"763"	"86.9"	"4.79"	"389.22"	"3.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00014, Pf02177, Pf10515, Pf12924, Pf12925"	"334"	"ENSG00000084234"	"APLP2"	"B3KXX9; H7BXI4; hsa:334; Q06481; Q13861; Q14594; Q14662; Q71U10; Q7M4L3; Q9BT36"	"Splicing factor NOVA regulated synaptic proteins"	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Platelet degranulation"	"4"	"0"	"13.9"	"17.2"	"12.2"	"20.8"	"16.4"	"9.3"	"17.6"	"20.5"	"24.4"	"77.6"	"101.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z3B4"	"Nucleoporin p54 OS=Homo sapiens OX=9606 GN=NUP54 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"507"	"55.4"	"7.02"	"371.04"	"3.81"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;nucleus"	"other molecular function"	"Pf13874, Pf18437"	"53371"	"ENSG00000138750"	"NUP54"	"B2RCK7; B4DT35; hsa:53371; Q7Z3B4; Q96EA7; Q9NVL5; Q9P0I1"	""	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Regulation of HSF1-mediated heat shock response; snRNP Assembly; ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; HCMV Late Events; HCMV Early Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; SUMOylation of SUMOylation proteins; SUMOylation of DNA replication proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00568"	"Adenylate kinase isoenzyme 1 OS=Homo sapiens OX=9606 GN=AK1 PE=1 SV=3"	""	""	"6"	"1"	"1"	"1"	"194"	"21.6"	"8.63"	""	"3.81"	""	"1"	"other metabolic processes"	"cytosol;cytoskeleton;other cell component"	"kinase activity;other molecular function"	"Pf00406"	"203"	"ENSG00000106992"	"AK1"	"hsa:203; P00568; Q9BVK9; Q9UQC7"	""	"Interconversion of nucleotide di- and triphosphates"	"1"	"0"	"9.3"	"10.1"	"9.1"	"15.3"	"12.8"	"3.9"	"18.5"	"17.8"	"27.9"	"153.6"	"399.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75531"	"Barrier-to-autointegration factor OS=Homo sapiens OX=9606 GN=BANF1 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"89"	"10.1"	"6.09"	"429.00"	"3.81"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02961"	"8815"	"ENSG00000175334"	"BANF1"	"hsa:8815; O60558; O75531; Q6FGG7"	"Envelope proteins and their potential roles in EDMD physiopathology; Familial partial lipodystrophy; Progeria-associated lipodystrophy"	"Vpr-mediated nuclear import of PICs; 2-LTR circle formation; Integration of viral DNA into host genomic DNA; Autointegration results in viral DNA circles; APOBEC3G mediated resistance to HIV-1 infection; Nuclear Envelope Breakdown; Initiation of Nuclear Envelope (NE) Reformation"	"11"	"0"	"81.5"	"125.6"	"108.1"	"217.6"	"70.9"	"77.3"	"139.5"	"142.1"	"179.4"	"348.3"	"356.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6F5"	"Coiled-coil domain-containing protein 86 OS=Homo sapiens OX=9606 GN=CCDC86 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"360"	"40.2"	"10.33"	"486.67"	"3.81"	"1"	"1"	""	"nucleus;other cell component"	""	"Pf03879"	"79080"	"ENSG00000110104"	"CCDC86"	"B4DY99; hsa:79080; Q9H6F5"	""	""	"0"	"0"	"11.8"	"10.2"	"10.9"	"14.8"	"14.1"	"11.6"	"15.9"	"13.1"	"21.9"	"38.0"	"52.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZN8"	"CCR4-NOT transcription complex subunit 2 OS=Homo sapiens OX=9606 GN=CNOT2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"540"	"59.7"	"7.66"	"502.34"	"3.80"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf04153"	"4848"	"ENSG00000111596"	"CNOT2"	"hsa:4848; Q9H3E0; Q9NSX5; Q9NWR6; Q9NZN8; Q9P028"	""	"Deadenylation of mRNA; TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"2"	"0"	"6.4"	"4.0"	"15.0"	"12.2"	"7.9"	"11.7"	"16.3"	"14.1"	"25.2"	"25.9"	"31.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BR76"	"Coronin-1B OS=Homo sapiens OX=9606 GN=CORO1B PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"489"	"54.2"	"5.88"	""	"3.79"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf08953, Pf16300"	"57175"	"ENSG00000172725"	"CORO1B"	"B2RD45; hsa:57175; Q9BR76"	""	""	"0"	"0"	"14.2"	"17.3"	"17.8"	"21.6"	"12.0"	"15.2"	"31.3"	"31.0"	"66.3"	"226.3"	"438.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14770"	"Homeobox protein Meis2 OS=Homo sapiens OX=9606 GN=MEIS2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"477"	"51.8"	"6.40"	"409.75"	"3.79"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05920, Pf16493"	"4212"	"ENSG00000134138"	"MEIS2"	"A6NJI5; A8MWD5; B3KP98; B3KPQ6; hsa:4212; O14770; Q96DI2; Q96KI4; Q96KI5; Q9NRS1; Q9NRS2; Q9NRS3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCE5"	"N6-adenosine-methyltransferase non-catalytic subunit OS=Homo sapiens OX=9606 GN=METTL14 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"456"	"52.1"	"6.21"	"439.39"	"3.79"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05063"	"57721"	"ENSG00000145388"	"METTL14"	"A6NIG1; hsa:57721; Q969V2; Q9HCE5"	"1p36 copy number variation syndrome"	"Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	"51.1"	"63.0"	"58.0"	"60.8"	"47.4"	"53.8"	"82.8"	"83.5"	"118.3"	"290.7"	"364.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62993"	"Growth factor receptor-bound protein 2 OS=Homo sapiens OX=9606 GN=GRB2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"217"	"25.2"	"6.32"	"281.70"	"3.78"	"1"	"1"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00018"	"2885"	"ENSG00000177885"	"GRB2"	"hsa:2885; P29354; P62993; Q14450; Q63057; Q63059"	"IL-5 signaling pathway; Integrin-mediated cell adhesion; Leptin signaling pathway; Prolactin signaling pathway; IL-9 signaling pathway; Pilocytic astrocytoma; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; p38 MAPK signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Thermogenesis; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; IL-2 signaling pathway; 7q11.23 copy number variation syndrome; 16p11.2 distal deletion syndrome; Modulators of TCR signaling and T cell activation; Kallmann syndrome; Pleural mesothelioma; Congenital generalized lipodystrophy; GDNF signaling; 2q13 copy number variation syndrome; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; 5q35 copy number variation; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"Signaling by ALK fusions and activated point mutants; Signaling by CSF3 (G-CSF); STAT5 activation downstream of FLT3 ITD mutants; Interleukin-15 signaling"	"68"	"0"	"50.2"	"73.0"	"49.3"	"86.2"	"50.4"	"41.1"	"74.5"	"110.8"	"162.5"	"212.5"	"289.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULW3"	"Activator of basal transcription 1 OS=Homo sapiens OX=9606 GN=ABT1 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"272"	"31.1"	"9.88"	"424.74"	"3.78"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"29777"	"ENSG00000146109"	"ABT1"	"hsa:29777; Q9ULW3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99653"	"Calcineurin B homologous protein 1 OS=Homo sapiens OX=9606 GN=CHP1 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"195"	"22.4"	"5.10"	"426.67"	"3.78"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;nucleus;other cell component"	"transporter activity;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00036"	"11261"	"ENSG00000187446"	"CHP1"	"B2R6H9; hsa:11261; Q6FHZ9; Q99653"	"T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection"	"Hyaluronan uptake and degradation"	"2"	"0"	"32.0"	"25.7"	"46.3"	"47.3"	"34.6"	"34.3"	"52.6"	"53.9"	"65.3"	"109.5"	"141.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15269"	"Periodic tryptophan protein 2 homolog OS=Homo sapiens OX=9606 GN=PWP2 PE=2 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"919"	"102.4"	"6.15"	"296.73"	"3.75"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400, Pf04003"	"5822"	"ENSG00000241945"	"PWP2"	"B2RAG8; hsa:5822; Q15269; Q96A77"	""	"rRNA modification in the nucleus and cytosol; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"34.7"	"36.5"	"47.3"	"59.9"	"38.7"	"38.2"	"99.4"	"113.1"	"168.0"	"515.8"	"740.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4B6"	"DDB1- and CUL4-associated factor 1 OS=Homo sapiens OX=9606 GN=DCAF1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1507"	"168.9"	"5.06"	"283.68"	"3.75"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	""	"9730"	"ENSG00000145041"	"DCAF1"	"hsa:9730; Q2YD74; Q8TBD9; Q9HCA1; Q9UG37; Q9Y4B6"	"Hippo-Merlin signaling dysregulation"	"Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	"30.8"	"29.3"	"27.8"	"39.9"	"34.0"	"28.4"	"46.2"	"53.4"	"62.7"	"129.1"	"165.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96C19"	"EF-hand domain-containing protein D2 OS=Homo sapiens OX=9606 GN=EFHD2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"240"	"26.7"	"5.20"	"440.69"	"3.74"	"1"	"1"	""	"other membranes"	"other molecular function"	"Pf13499"	"79180"	"ENSG00000142634"	"EFHD2"	"hsa:79180; Q5JYW9; Q96C19"	""	"RHOD GTPase cycle"	"1"	"0"	"54.5"	"39.6"	"50.5"	"81.7"	"41.3"	"53.1"	"75.8"	"90.8"	"129.1"	"271.8"	"416.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y478"	"5'-AMP-activated protein kinase subunit beta-1 OS=Homo sapiens OX=9606 GN=PRKAB1 PE=1 SV=4"	"0.000"	""	"7"	"1"	"2"	"1"	"270"	"30.4"	"6.40"	"347.56"	"3.74"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf04739, Pf16561"	"5564"	"ENSG00000111725"	"PRKAB1"	"hsa:5564; Q9UBV0; Q9UE20; Q9UEX2; Q9Y478; Q9Y6V8"	"AMP-activated protein kinase signaling; Target of rapamycin signaling; Energy metabolism; Sterol regulatory element-binding proteins (SREBP) signaling; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Angiopoietin-like protein 8 regulatory pathway; Leptin and adiponectin; Lipid metabolism pathway; Thermogenesis; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Hippo signaling regulation pathways; 1q21.1 copy number variation syndrome; Autophagy; p53 transcriptional gene network; Pleural mesothelioma"	"Regulation of TP53 Activity through Phosphorylation; Macroautophagy; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Activation of AMPK downstream of NMDARs; TP53 Regulates Metabolic Genes; Energy dependent regulation of mTOR by LKB1-AMPK; Activation of PPARGC1A (PGC-1alpha) by phosphorylation; Lipophagy"	"24"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13111"	"Chromatin assembly factor 1 subunit A OS=Homo sapiens OX=9606 GN=CHAF1A PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"956"	"106.8"	"5.94"	"377.03"	"3.74"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf11600, Pf12253, Pf15539, Pf15557"	"10036"	"ENSG00000167670"	"CHAF1A"	"hsa:10036; Q13111; Q6NXG5; Q7Z7K3; Q9UJY8"	"Nanoparticle triggered autophagic cell death"	""	"1"	"0"	"27.6"	"14.6"	"33.6"	"30.7"	"28.3"	"25.3"	"31.4"	"36.9"	"45.9"	"60.6"	"85.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BQC6"	"Ribosomal protein 63, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL57 PE=1 SV=1"	"0.000"	""	"13"	"1"	"2"	"1"	"102"	"12.3"	"11.44"	"338.30"	"3.74"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf14978"	"78988"	"ENSG00000173141"	"MRPL57"	"A2A332; hsa:78988; Q9BQC6"	""	"Mitochondrial translation elongation; Mitochondrial translation initiation; Mitochondrial translation termination"	"3"	"0"	"39.6"	"31.4"	"50.0"	"54.1"	"32.1"	"38.2"	"50.7"	"67.6"	"87.9"	"207.6"	"240.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EV8"	"Dysbindin OS=Homo sapiens OX=9606 GN=DTNBP1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"351"	"39.5"	"4.67"	"345.71"	"3.73"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf04440"	"84062"	"ENSG00000047579"	"DTNBP1"	"A8K3V3; hsa:84062; Q5THY3; Q5THY4; Q96EV8; Q96NV2; Q9H0U2; Q9H3J5"	"Alstrom syndrome"	"Golgi Associated Vesicle Biogenesis"	"2"	"0"	"40.6"	"38.8"	"40.3"	"48.9"	"39.3"	"38.1"	"59.6"	"76.5"	"95.6"	"497.8"	"853.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96B26"	"Exosome complex component RRP43 OS=Homo sapiens OX=9606 GN=EXOSC8 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"276"	"30.0"	"5.30"	"354.60"	"3.73"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"11340"	"ENSG00000120699"	"EXOSC8"	"hsa:11340; O43480; Q5TBA5; Q96B26"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"11.9"	"11.6"	"21.7"	"22.9"	"17.5"	"12.4"	"24.9"	"36.6"	"43.4"	"111.6"	"148.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95251"	"Histone acetyltransferase KAT7 OS=Homo sapiens OX=9606 GN=KAT7 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"611"	"70.6"	"8.85"	""	"3.73"	""	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01530, Pf01853, Pf17772"	"11143"	"ENSG00000136504"	"KAT7"	"B3KN74; B4DF85; B4DFB4; B4DFE0; B4DGY4; E7ER15; G5E9K7; hsa:11143; O95251"	"Androgen receptor signaling pathway"	"HATs acetylate histones"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H488"	"GDP-fucose protein O-fucosyltransferase 1 OS=Homo sapiens OX=9606 GN=POFUT1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"388"	"43.9"	"8.53"	"314.56"	"3.73"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf10250"	"23509"	"ENSG00000101346"	"POFUT1"	"A8K4R8; E1P5M4; hsa:23509; Q14685; Q5W185; Q9BW76; Q9H488"	""	"Pre-NOTCH Processing in the Endoplasmic Reticulum"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82675"	"28S ribosomal protein S5, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS5 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"430"	"48.0"	"9.92"	"407.75"	"3.72"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00333, Pf03719"	"64969"	"ENSG00000144029"	"MRPS5"	"hsa:64969; P82675; Q4ZFY5; Q96LJ6; Q9BWI4; Q9BYC4"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"37.1"	"36.0"	"48.3"	"60.6"	"44.0"	"47.5"	"54.8"	"58.6"	"61.6"	"76.8"	"138.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WWV3"	"Reticulon-4-interacting protein 1, mitochondrial OS=Homo sapiens OX=9606 GN=RTN4IP1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"396"	"43.6"	"9.11"	"405.80"	"3.71"	"1"	"1"	"developmental processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf08240, Pf13602"	"84816"	"ENSG00000130347"	"RTN4IP1"	"hsa:84816; Q8N9B3; Q8WWV3; Q8WZ66; Q9BRA4"	""	""	"0"	"0"	"8.6"	"12.3"	"9.8"	"15.8"	"10.4"	"11.2"	"20.6"	"19.6"	"34.5"	"87.6"	"129.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43865"	"S-adenosylhomocysteine hydrolase-like protein 1 OS=Homo sapiens OX=9606 GN=AHCYL1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"530"	"58.9"	"6.89"	"863.02"	"3.71"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00670, Pf05221"	"10768"	"ENSG00000168710"	"AHCYL1"	"B4E168; hsa:10768; O43865; Q2TAJ6; Q502W8; Q5VSM0; Q6P171; Q96PK4; Q9UG84"	"Trans-sulfuration, one-carbon metabolism and related pathways"	"Role of phospholipids in phagocytosis; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Ion homeostasis; Regulation of insulin secretion; VEGFR2 mediated cell proliferation; PLC beta mediated events; DAG and IP3 signaling; CLEC7A (Dectin-1) induces NFAT activation"	"11"	"0"	"78.6"	"69.7"	"84.9"	"91.0"	"78.8"	"79.5"	"112.7"	"114.1"	"141.5"	"301.5"	"436.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13952"	"Nuclear transcription factor Y subunit gamma OS=Homo sapiens OX=9606 GN=NFYC PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"458"	"50.3"	"6.10"	"354.69"	"3.71"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00125"	"4802"	"ENSG00000066136"	"NFYC"	"B4DUS6; B4DW63; D3DPV9; F8VWM3; hsa:4802; Q13952; Q59GY4; Q5T6K8; Q5T6K9; Q5T6L1; Q5TZR6; Q92869; Q9HBX1; Q9NXB5; Q9UM67; Q9UML0; Q9UMT7"	""	"PPARA activates gene expression; Activation of gene expression by SREBF (SREBP); FOXO-mediated transcription of cell death genes; ATF4 activates genes in response to endoplasmic reticulum  stress; ATF6 (ATF6-alpha) activates chaperone genes"	"5"	"0"	"29.7"	"28.5"	"47.4"	"50.2"	"29.8"	"35.3"	"61.6"	"53.6"	"99.1"	"276.5"	"312.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47756"	"F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"277"	"31.3"	"5.59"	"359.20"	"3.70"	"1"	"1"	"cell organization and biogenesis"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf01115"	"100612860; 101140941"	"ENSGGOG00000003982; ENSPPYG00000001789; ENSPTRG00000000268"	"CAPZB"	"A0A2J8KEQ9; A0A2J8T2J3; A0A6D2W7V0; A0A6D2XKL1; A0A8B6ZIG4; A0A9B0TL78; G3QN07; H2N8T0; H2R9E0"	""	""	"0"	"0"	"93.2"	"56.8"	"135.5"	"143.2"	"97.4"	"92.1"	"144.1"	"149.0"	"203.9"	"384.2"	"631.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38117"	"Electron transfer flavoprotein subunit beta OS=Homo sapiens OX=9606 GN=ETFB PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"255"	"27.8"	"8.10"	"495.69"	"3.70"	"1"	"1"	"other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01012"	"2109"	"ENSG00000105379"	"ETFB"	"A8K766; B3KNY2; hsa:2109; P38117; Q6IBH7; Q71RF6; Q9Y3S7"	""	"Respiratory electron transport; Protein methylation"	"2"	"0"	"20.8"	"10.5"	"18.7"	"30.8"	"12.3"	"18.9"	"28.0"	"30.0"	"46.2"	"91.5"	"191.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7RTN6"	"STE20-related kinase adapter protein alpha OS=Homo sapiens OX=9606 GN=STRADA PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"431"	"48.3"	"6.48"	"297.37"	"3.70"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00069"	"92335"	"ENSG00000266173"	"STRADA"	"B4DDE3; B4DW17; hsa:92335; J3KTC9; Q5JPI2; Q7RTN6; Q7Z4K9; Q8NC31; Q8NCF1; Q9H272"	"AMP-activated protein kinase signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway"	"Energy dependent regulation of mTOR by LKB1-AMPK"	"3"	"0"	"8.4"	"6.3"	"6.8"	"10.5"	"7.7"	"6.4"	"33.2"	"36.0"	"66.4"	"111.2"	"114.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H7E2"	"Tudor domain-containing protein 3 OS=Homo sapiens OX=9606 GN=TDRD3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"651"	"73.1"	"9.23"	"340.21"	"3.70"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00567, Pf00627, Pf08585"	"81550"	"ENSG00000083544"	"TDRD3"	"B2MWP9; hsa:81550; Q53XA6; Q6P992; Q9H7E2"	""	""	"0"	"0"	"4.0"	"6.2"	"9.1"	"9.4"	"5.7"	"7.4"	"10.6"	"8.9"	"9.3"	"24.9"	"33.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QD9"	"UAP56-interacting factor OS=Homo sapiens OX=9606 GN=FYTTD1 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"318"	"35.8"	"11.78"	"368.67"	"3.69"	"1"	"1"	"other metabolic processes;transport"	"nucleus"	"nucleic acid binding activity"	"Pf07078"	"84248"	"ENSG00000122068"	"FYTTD1"	"A8MY74; B2RCB2; B7Z3R4; B7Z7V1; B7Z8I0; B7ZAJ3; C9J7P6; C9JNG6; C9JTH3; C9JY50; hsa:84248; Q96QD9; Q96SL9; Q9BQI8"	""	"Transport of Mature mRNA derived from an Intron-Containing Transcript; mRNA 3'-end processing; RNA Polymerase II Transcription Termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93074"	"Mediator of RNA polymerase II transcription subunit 12 OS=Homo sapiens OX=9606 GN=MED12 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"2177"	"242.9"	"7.05"	"349.14"	"3.68"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09497, Pf12144, Pf12145"	"9968"	"ENSG00000184634"	"MED12"	"hsa:9968; O15410; O75557; Q93074; Q9UHV6; Q9UND7"	""	"Transcriptional regulation of white adipocyte differentiation; PPARA activates gene expression; Generic Transcription Pathway"	"3"	"0"	"5.7"	"8.7"	"8.3"	"11.4"	"7.3"	"7.5"	"13.8"	"10.5"	"13.7"	"46.9"	"71.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7L2H7"	"Eukaryotic translation initiation factor 3 subunit M OS=Homo sapiens OX=9606 GN=EIF3M PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"374"	"42.5"	"5.63"	""	"3.68"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01399, Pf18005"	"10480"	"ENSG00000149100"	"EIF3M"	"A8K7X4; B4E2Q4; hsa:10480; O60735; Q2F836; Q53HL6; Q7L2H7; Q9BXW1"	""	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Translation initiation complex formation; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition"	"6"	"0"	"16.8"	"21.9"	"19.8"	"25.7"	"19.9"	"22.7"	"33.9"	"39.0"	"39.4"	"156.5"	"608.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUQ8"	"ATP-binding cassette sub-family F member 3 OS=Homo sapiens OX=9606 GN=ABCF3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"709"	"79.7"	"6.34"	"497.99"	"3.68"	"1"	"1"	"stress response"	""	"other molecular function"	"Pf00005, Pf12848"	"55324"	"ENSG00000161204"	"ABCF3"	"A8K241; hsa:55324; Q86UA2; Q8NAN1; Q96GS8; Q9H7A8; Q9NUQ8"	""	""	"0"	"0"	"24.7"	"23.5"	"28.0"	"27.3"	"19.9"	"26.0"	"45.8"	"38.6"	"60.4"	"128.3"	"126.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13464"	"Rho-associated protein kinase 1 OS=Homo sapiens OX=9606 GN=ROCK1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1354"	"158.1"	"5.90"	"286.80"	"3.68"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf08912"	"6093"	"ENSG00000067900"	"ROCK1"	"B0YJ91; hsa:6093; Q13464; Q2KHM4; Q59GZ4"	"Androgen receptor signaling pathway; MicroRNAs in cardiomyocyte hypertrophy; Integrin-mediated cell adhesion; Leptin signaling pathway; Microtubule cytoskeleton regulation; Pathogenic Escherichia coli infection; AGE/RAGE pathway; Focal adhesion; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; EGF/EGFR signaling pathway; Gastrin signaling pathway; mBDNF and proBDNF regulation of GABA neurotransmission; MAP3K1 role in promoting and blocking gonadal determination; Airway smooth muscle cell contraction; RAS and bradykinin pathways in COVID-19; Regulation of actin cytoskeleton; GDNF signaling; G13 signaling pathway"	"EPHB-mediated forward signaling; Neutrophil degranulation; G alpha (12/13) signalling events; Potential therapeutics for SARS; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle; VEGFA-VEGFR2 Pathway; RND3 GTPase cycle; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases Activate ROCKs; RHOBTB1 GTPase cycle; RHOH GTPase cycle; Apoptotic cleavage of cellular proteins"	"34"	"0"	"8.1"	"7.2"	"12.8"	"14.6"	"9.6"	"13.0"	"14.6"	"15.3"	"28.0"	"113.5"	"241.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVK2"	"U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP27 PE=1 SV=1"	"0.000"	""	"17"	"2"	"3"	"2"	"155"	"18.8"	"11.62"	"1028.73"	"3.67"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf08648"	"11017"	"ENSG00000124380"	"SNRNP27"	"hsa:11017; Q15410; Q8WVK2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"117.2"	"108.4"	"94.1"	"121.0"	"95.5"	"94.7"	"190.1"	"213.0"	"340.2"	"1039.4"	"1173.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75554"	"WW domain-binding protein 4 OS=Homo sapiens OX=9606 GN=WBP4 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"376"	"42.5"	"5.57"	"399.20"	"3.67"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00397, Pf06220"	"11193"	"ENSG00000120688"	"WBP4"	"B7Z4M2; hsa:11193; O75554; Q32P29"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12532"	"Creatine kinase U-type, mitochondrial OS=Homo sapiens OX=9606 GN=CKMT1A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"417"	"47.0"	"8.34"	"457.29"	"3.66"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf00217, Pf02807"	"1159; 548596"	"ENSG00000223572; ENSG00000237289"	"CKMT1A; CKMT1B"	"B4DIT8; B7ZA09; hsa:1159; hsa:548596; P12532; Q0VAM3; Q32NF6; Q53FC4"	""	"Creatine metabolism"	"1"	"0"	"55.2"	"47.8"	"60.6"	"73.1"	"55.1"	"49.0"	"94.3"	"88.0"	"131.4"	"267.1"	"409.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5JSH3"	"WD repeat-containing protein 44 OS=Homo sapiens OX=9606 GN=WDR44 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"913"	"101.3"	"5.45"	""	"3.66"	""	"1"	""	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf00400"	"54521"	"ENSG00000131725"	"WDR44"	"B4DSE9; F8W913; hsa:54521; Q0JS52; Q0JTF3; Q5JSH2; Q5JSH3; Q6ZSC1; Q7Z365; Q7Z3P6; Q8NAU8; Q8NHU5; Q9NUV4"	"Ectoderm differentiation"	""	"1"	"0"	"13.8"	"8.3"	"13.9"	"15.3"	"11.2"	"13.0"	"29.9"	"24.5"	"38.9"	"165.6"	"260.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z739"	"YTH domain-containing family protein 3 OS=Homo sapiens OX=9606 GN=YTHDF3 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"585"	"63.8"	"9.04"	"688.86"	"3.65"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;other cell component"	"translation activity;nucleic acid binding activity"	"Pf04146"	"253943"	"ENSG00000185728"	"YTHDF3"	"B3KXL4; hsa:253943; Q63Z37; Q659A3; Q7Z739"	""	""	"0"	"0"	"258.1"	"216.5"	"231.2"	"221.5"	"207.9"	"243.0"	"323.6"	"277.5"	"347.6"	"792.7"	"1081.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UY8"	"5'-nucleotidase domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NT5DC3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"548"	"63.4"	"8.31"	"271.90"	"3.65"	"1"	"1"	""	"cytosol;other cell component"	"other molecular function"	"Pf05761"	"51559"	"ENSG00000111696"	"NT5DC3"	"hsa:51559; Q86UY8; Q9NUM7; Q9P2T2; Q9P2T3"	""	""	"0"	"0"	"67.7"	"21.4"	"103.4"	"94.9"	"75.8"	"78.0"	"77.9"	"58.3"	"83.8"	"152.4"	"236.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZ63"	"Telomere length and silencing protein 1 homolog OS=Homo sapiens OX=9606 GN=C9orf78 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"289"	"33.7"	"6.74"	"287.73"	"3.65"	"1"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf07052"	"51759"	"ENSG00000136819"	"C9orf78"	"B3KPX8; hsa:51759; Q8WVU6; Q9NT39; Q9NZ63"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"17.0"	"15.1"	"22.0"	"23.5"	"21.5"	"21.1"	"36.8"	"27.6"	"35.4"	"143.4"	"277.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5NDL2"	"EGF domain-specific O-linked N-acetylglucosamine transferase OS=Homo sapiens OX=9606 GN=EOGT PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"527"	"62.0"	"7.05"	"297.39"	"3.63"	"1"	"1"	"protein metabolism;other metabolic processes"	"ER/Golgi"	"other molecular function"	"Pf04577"	"285203"	"ENSG00000163378"	"EOGT"	"A8K2U1; B4DFH5; hsa:285203; L7X1M5; Q5NDL2; Q6MZY0; Q6P985; Q6ZTV0"	"Genetic causes of porto-sinusoidal vascular disease"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75718"	"Cartilage-associated protein OS=Homo sapiens OX=9606 GN=CRTAP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"401"	"46.5"	"5.73"	"388.69"	"3.63"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	""	""	"10491"	"ENSG00000170275"	"CRTAP"	"B2RBL6; hsa:10491; O75718"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"47.7"	"43.6"	"54.1"	"103.5"	"42.9"	"28.7"	"104.9"	"102.8"	"148.1"	"285.5"	"367.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPB8"	"Glycerophosphocholine phosphodiesterase GPCPD1 OS=Homo sapiens OX=9606 GN=GPCPD1 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"672"	"76.0"	"5.53"	"901.32"	"3.63"	"2"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf00686, Pf03009"	"56261"	"ENSG00000125772"	"GPCPD1"	"D3DW06; hsa:56261; Q9BQL8; Q9NPB8; Q9NUX0"	""	"Hydrolysis of LPC; Hydrolysis of LPE"	"2"	"0"	"7.7"	"9.1"	"8.5"	"11.1"	"10.4"	"9.9"	"62.5"	"74.9"	"160.9"	"574.9"	"696.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15139"	"Serine/threonine-protein kinase D1 OS=Homo sapiens OX=9606 GN=PRKD1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"912"	"101.6"	"6.62"	"355.91"	"3.62"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00169"	"5587"	"ENSG00000184304"	"PRKD1"	"A6NL64; B2RAF6; hsa:5587; Q15139"	"Apoptosis modulation and signaling; Cardiac hypertrophic response; Myometrial relaxation and contraction pathways; G protein signaling pathways; VEGFA-VEGFR2 signaling; Wnt signaling pathway and pluripotency; Gastrin signaling pathway; Osteoblast differentiation and related diseases; Calcium regulation in cardiac cells"	"Sphingolipid de novo biosynthesis"	"10"	"0"	"18.3"	"13.6"	"20.1"	"32.3"	"19.2"	"19.4"	"35.6"	"34.0"	"41.1"	"112.5"	"135.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16403"	"Histone H1.2 OS=Homo sapiens OX=9606 GN=H1-2 PE=1 SV=2"	"0.000"	""	"9"	"2"	"3"	"2"	"213"	"21.4"	"10.93"	"896.05"	"3.62"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00538"	"3006"	"ENSG00000187837"	"H1-2"	"A8K4I2; hsa:3006; P16403"	""	"Apoptosis induced DNA fragmentation; Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"2"	"0"	"156.1"	"119.5"	"190.7"	"276.5"	"150.4"	"166.0"	"244.5"	"264.6"	"331.0"	"521.0"	"853.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5JVF3"	"PCI domain-containing protein 2 OS=Homo sapiens OX=9606 GN=PCID2 PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"399"	"46.0"	"8.53"	""	"3.61"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf01399"	"55795"	"ENSG00000126226"	"PCID2"	"A6NK09; hsa:55795; Q3ZCX1; Q5JVF3; Q5TC57; Q5TC58; Q9H7K1; Q9HBZ7; Q9NUK6; Q9NVY1; Q9NW44; Q9NWH3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YB8"	"ERO1-like protein beta OS=Homo sapiens OX=9606 GN=ERO1B PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"467"	"53.5"	"7.99"	"289.58"	"3.61"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf04137"	"56605"	"ENSG00000086619"	"ERO1B"	"B4DF57; hsa:56605; Q5T1H4; Q86YB8; Q8IZ11; Q9NR62"	""	"Insulin processing"	"1"	"0"	"5.5"	"3.1"	"6.2"	"10.2"	"3.8"	"7.4"	"28.9"	"29.9"	"66.3"	"141.1"	"183.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14919"	"Dr1-associated corepressor OS=Homo sapiens OX=9606 GN=DRAP1 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"205"	"22.3"	"5.17"	"339.45"	"3.61"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"10589"	"ENSG00000175550"	"DRAP1"	"hsa:10589; Q13448; Q14919"	""	"Signaling by NODAL; Signaling by Activin"	"2"	"0"	"44.2"	"41.3"	"46.1"	"57.7"	"44.7"	"43.8"	"81.2"	"91.8"	"116.2"	"321.1"	"725.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BZG8"	"2-(3-amino-3-carboxypropyl)histidine synthase subunit 1 OS=Homo sapiens OX=9606 GN=DPH1 PE=1 SV=2"	""	""	"5"	"1"	"1"	"1"	"443"	"48.8"	"8.18"	""	"3.61"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"23.8"	"21.1"	"48.0"	"39.3"	"27.2"	"15.0"	"54.6"	"60.6"	"72.8"	"178.3"	"255.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HD34"	"LYR motif-containing protein 4 OS=Homo sapiens OX=9606 GN=LYRM4 PE=1 SV=1"	"0.000"	""	"15"	"1"	"2"	"1"	"91"	"10.8"	"10.73"	"455.49"	"3.61"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf05347"	"57128"	"ENSG00000214113"	"LYRM4"	"A8K543; hsa:57128; Q5XKP1; Q9HD34"	"Iron-sulfur cluster biogenesis"	"Mitochondrial iron-sulfur cluster biogenesis"	"2"	"0"	"31.8"	"19.7"	"38.7"	"53.4"	"42.1"	"38.1"	"67.1"	"67.4"	"110.1"	"226.0"	"326.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUB8"	"PHD finger protein 10 OS=Homo sapiens OX=9606 GN=PHF10 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"498"	"56.0"	"6.62"	"407.76"	"3.61"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628"	"55274"	"ENSG00000130024"	"PHF10"	"hsa:55274; Q2YDA3; Q53HG8; Q8WUB8; Q9BXD2; Q9NV26"	""	""	"0"	"0"	"8.4"	"10.3"	"7.6"	"10.3"	"9.7"	"7.4"	"10.7"	"17.4"	"16.6"	"33.7"	"30.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YP4"	"Transcriptional repressor p66-alpha OS=Homo sapiens OX=9606 GN=GATAD2A PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"633"	"68.0"	"9.94"	"409.97"	"3.61"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00320, Pf16563"	"54815"	"ENSG00000167491"	"GATAD2A"	"B5MC40; hsa:54815; Q7L3J2; Q86YP4; Q96F28; Q9NPU2; Q9NXS1"	""	"RNA Polymerase I Transcription Initiation; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; HDACs deacetylate histones; Regulation of TP53 Activity through Acetylation"	"6"	"0"	"74.9"	"85.0"	"77.2"	"88.5"	"70.8"	"65.9"	"94.4"	"102.3"	"105.2"	"265.4"	"371.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GC5"	"39S ribosomal protein L48, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL48 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"212"	"23.9"	"8.98"	"375.32"	"3.61"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf00338"	"51642"	"ENSG00000175581"	"MRPL48"	"B4DN34; hsa:51642; Q49AK7; Q4U2Q4; Q96GC5; Q9P091; Q9Y5J0"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"43.5"	"50.1"	"42.7"	"53.1"	"42.6"	"42.5"	"58.8"	"58.3"	"56.4"	"121.4"	"181.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P2X3"	"Protein IMPACT OS=Homo sapiens OX=9606 GN=IMPACT PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"320"	"36.5"	"4.97"	""	"3.60"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"other cell component"	"cytoskeletal activity;translation activity;other molecular function"	"Pf01205, Pf05773"	"55364"	"ENSG00000154059"	"IMPACT"	"A8MXG0; hsa:55364; Q49AM0; Q9H2X4; Q9P2X3"	""	"Response of EIF2AK4 (GCN2) to amino acid deficiency"	"1"	"0"	"0.0"	"3.4"	"0.0"	"2.4"	"5.7"	"1.9"	"3.9"	"3.9"	"4.8"	"24.5"	"67.1"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14530"	"Thioredoxin domain-containing protein 9 OS=Homo sapiens OX=9606 GN=TXNDC9 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"226"	"26.5"	"5.88"	"332.74"	"3.59"	"1"	"1"	"cell organization and biogenesis"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00085"	"10190"	"ENSG00000115514"	"TXNDC9"	"B2R9G8; D3DVI4; hsa:10190; O14530; Q53HG4; Q53RV8; Q6NSF5; Q8TB70; Q9BRU6"	""	""	"0"	"0"	"4.3"	"6.7"	"7.7"	"9.8"	"2.6"	"6.1"	"15.4"	"13.4"	"12.8"	"153.7"	"306.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6H8Y1"	"Transcription factor TFIIIB component B'' homolog OS=Homo sapiens OX=9606 GN=BDP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2624"	"293.7"	"5.11"	"393.36"	"3.59"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf15963"	"55814"	"ENSG00000145734; ENSG00000273873"	"BDP1"	"A6H8Y1; hsa:55814; Q68DS6; Q68DY5; Q6MZL9; Q6PIM7; Q86W98; Q96LR8; Q9C0H4; Q9H197; Q9H1A1; Q9HAW1; Q9HAW2; Q9HCY0; Q9ULH9"	""	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6U6"	"Breast carcinoma-amplified sequence 3 OS=Homo sapiens OX=9606 GN=BCAS3 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"928"	"101.2"	"6.70"	"369.29"	"3.58"	"1"	"1"	"cell-cell signaling;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf12490"	"54828"	"ENSG00000141376"	"BCAS3"	"hsa:54828; Q17RM0; Q6KF21; Q8IXI6; Q8NDR8; Q8TDL9; Q8TDM1; Q8WY55; Q9BVF0; Q9H6U6; Q9H957; Q9H9Y9; Q9NXP4"	"Ectoderm differentiation"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QT6"	"PHD finger protein 12 OS=Homo sapiens OX=9606 GN=PHF12 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1004"	"109.6"	"7.74"	"393.44"	"3.58"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00628, Pf16737"	"57649"	"ENSG00000109118"	"PHF12"	"hsa:57649; Q0VAI5; Q2TAK2; Q6ZML2; Q96QT6; Q9BV34; Q9H7U9; Q9P205"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y613"	"FH1/FH2 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FHOD1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1164"	"126.5"	"6.39"	"510.27"	"3.58"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf18382"	"29109"	"ENSG00000135723"	"FHOD1"	"hsa:29109; Q59F76; Q6Y1F2; Q76MS8; Q8N521; Q9Y613"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"35.5"	"34.4"	"57.6"	"55.4"	"44.9"	"41.7"	"73.8"	"72.1"	"77.2"	"156.8"	"178.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15118"	"[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial OS=Homo sapiens OX=9606 GN=PDK1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"436"	"49.2"	"8.81"	"529.24"	"3.58"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"mitochondrion"	"kinase activity;other molecular function"	"Pf02518, Pf10436"	"5163"	"ENSG00000152256"	"PDK1"	"B2R6T1; B7Z937; D3DPD8; E9PD65; hsa:5163; Q15118; Q308M4"	"T cell receptor and co-stimulatory signaling; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Non-small cell lung cancer; Fragile X syndrome; Translation inhibitors in chronically activated PDGFRA cells; Aspirin and miRNAs; PKC-gamma calcium signaling pathway in ataxia; Kisspeptin/kisspeptin receptor system in the ovary; TCA cycle in senescence; Pleural mesothelioma; Orexin receptor pathway; Resolvin E1 and resolvin D1 signaling pathways promoting inflammation resolution; Glucose metabolism in triple-negative breast cancer cells; EPO receptor signaling; DNA damage response (only ATM dependent)"	"Signaling by Retinoic Acid; Regulation of pyruvate dehydrogenase (PDH) complex"	"19"	"0"	"23.7"	"34.0"	"32.7"	"30.6"	"25.9"	"28.2"	"59.4"	"69.1"	"119.8"	"249.0"	"275.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR09"	"Baculoviral IAP repeat-containing protein 6 OS=Homo sapiens OX=9606 GN=BIRC6 PE=1 SV=2"	"0.000"	""	"0"	"1"	"2"	"1"	"4857"	"529.9"	"6.05"	"344.25"	"3.58"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"23.9"	"19.8"	"26.7"	"32.2"	"22.6"	"18.9"	"32.1"	"29.5"	"42.6"	"74.0"	"109.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75449"	"Katanin p60 ATPase-containing subunit A1 OS=Homo sapiens OX=9606 GN=KATNA1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"491"	"55.9"	"6.90"	"363.89"	"3.57"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00004, Pf09336, Pf17862"	"11104"	"ENSG00000186625"	"KATNA1"	"E1P5A3; hsa:11104; O75449; Q5TFA8; Q5TFA9; Q86VN2; Q9NU52"	""	""	"0"	"0"	"4.6"	"4.8"	"8.5"	"12.4"	"6.1"	"6.6"	"17.9"	"12.8"	"27.5"	"99.5"	"123.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TB45"	"DEP domain-containing mTOR-interacting protein OS=Homo sapiens OX=9606 GN=DEPTOR PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"409"	"46.3"	"8.07"	"342.65"	"3.57"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	""	""	"Pf00610"	"64798"	"ENSG00000155792"	"DEPTOR"	"B2RCL9; B4DN97; E7EV87; hsa:64798; Q8TB45; Q96EQ1; Q9H0R7; Q9H894; Q9HA07"	"Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Clear cell renal cell carcinoma pathways; Fragile X syndrome; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; p53 transcriptional gene network; Pleural mesothelioma; Network map of SARS-CoV-2 signaling pathway; DYRK1A involvement regarding cell proliferation in brain development"	""	"9"	"0"	"16.9"	"15.1"	"19.0"	"19.8"	"20.4"	"16.0"	"31.6"	"45.0"	"74.5"	"143.3"	"157.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YT6"	"E3 ubiquitin-protein ligase MIB1 OS=Homo sapiens OX=9606 GN=MIB1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1006"	"110.1"	"6.92"	"338.23"	"3.56"	"1"	"1"	"protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00569, Pf06701, Pf12796, Pf13920, Pf18346"	"57534"	"ENSG00000101752"	"MIB1"	"B0YJ38; hsa:57534; Q2TB37; Q68D01; Q6YI51; Q86YT6; Q8NBY0; Q8TCB5; Q8TCL7; Q9P2M3"	"Genes related to primary cilium development (based on CRISPR)"	"Activated NOTCH1 Transmits Signal to the Nucleus; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; NOTCH2 Activation and Transmission of Signal to the Nucleus; NOTCH3 Activation and Transmission of Signal to the Nucleus"	"7"	"0"	"19.0"	"23.8"	"24.8"	"29.9"	"20.1"	"20.7"	"35.3"	"38.4"	"61.4"	"153.5"	"179.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H270"	"Vacuolar protein sorting-associated protein 11 homolog OS=Homo sapiens OX=9606 GN=VPS11 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"941"	"107.8"	"7.05"	"302.72"	"3.56"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00637, Pf12451, Pf13923"	"55823"	""	"VPS11"	"hsa:55823; Q8WY89; Q96EP8; Q9H270; Q9H6D9; Q9HCS6"	"Network map of SARS-CoV-2 signaling pathway"	"SARS-CoV-2 modulates autophagy"	"2"	"0"	"3.0"	"4.0"	"9.9"	"8.4"	"1.8"	"5.4"	"12.1"	"11.3"	"15.2"	"32.8"	"66.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12846"	"Syntaxin-4 OS=Homo sapiens OX=9606 GN=STX4 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"297"	"34.2"	"6.28"	"317.77"	"3.56"	"1"	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00804, Pf05739"	"6810"	"ENSG00000103496"	"STX4"	"A8MXY0; hsa:6810; Q12846; Q15525; Q6FHE8"	"Insulin signaling"	"ER-Phagosome pathway; Translocation of SLC2A4 (GLUT4) to the plasma membrane; trans-Golgi Network Vesicle Budding; Disinhibition of SNARE formation; Other interleukin signaling"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96H20"	"Vacuolar-sorting protein SNF8 OS=Homo sapiens OX=9606 GN=SNF8 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"258"	"28.8"	"6.65"	"622.61"	"3.56"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04157"	"11267"	"ENSG00000159210"	"SNF8"	"hsa:11267; Q8IXY3; Q96H20; Q9UN50"	""	"Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events"	"2"	"0"	"93.1"	"69.5"	"116.9"	"163.5"	"132.2"	"188.5"	"415.1"	"435.0"	"611.5"	"1181.6"	"1400.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6KC79"	"Nipped-B-like protein OS=Homo sapiens OX=9606 GN=NIPBL PE=1 SV=2"	"0.000"	""	"1"	"2"	"3"	"2"	"2804"	"315.9"	"7.91"	"681.22"	"3.55"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12765, Pf12830"	"25836"	"ENSG00000164190"	"NIPBL"	"hsa:25836; Q6KC79; Q6KCD6; Q6N080; Q6ZT92; Q7Z2E6; Q8N4M5; Q9Y6Y3; Q9Y6Y4"	"Cohesin complex - Cornelia de Lange syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Cohesin Loading onto Chromatin"	"3"	"0"	"78.3"	"69.1"	"82.8"	"87.6"	"73.9"	"85.5"	"120.0"	"144.6"	"192.4"	"417.5"	"581.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZF9"	"Uveal autoantigen with coiled-coil domains and ankyrin repeats OS=Homo sapiens OX=9606 GN=UACA PE=1 SV=2"	"0.000"	""	"3"	"5"	"6"	"3"	"1416"	"162.4"	"7.03"	"1407.60"	"3.55"	"5"	"1"	"other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf12796"	"55075"	"ENSG00000137831"	"UACA"	"G3XAG2; hsa:55075; Q14DD3; Q8N3B8; Q96NH6; Q9BZF9; Q9HCL1; Q9NWC6"	""	"Regulation of the apoptosome activity; RHOH GTPase cycle"	"2"	"0"	"62.3"	"60.9"	"67.8"	"72.7"	"60.6"	"71.9"	"132.2"	"151.3"	"207.2"	"468.5"	"502.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14671"	"Pumilio homolog 1 OS=Homo sapiens OX=9606 GN=PUM1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1186"	"126.4"	"6.84"	"548.03"	"3.54"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00806"	"9698"	"ENSG00000134644"	"PUM1"	"A8K6W4; B4DG92; D3DPN3; E9PCJ0; hsa:9698; Q14671; Q53HH5; Q5VXY7; Q9HAN1"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48507"	"Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"274"	"30.7"	"6.02"	"396.41"	"3.54"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00248"	"2730"	"ENSG00000023909"	"GCLM"	"A8K334; D3DT45; hsa:2730; M5A959; P48507; Q6FHC1; Q9NPX9; Q9NU74"	"Glutathione metabolism; Trans-sulfuration pathway; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Transcriptional activation by NRF2 in response to phytochemicals; Photodynamic therapy-induced NFE2L2 (NRF2) survival signaling; Amino acid metabolism; Ferroptosis; NRF2-ARE regulation; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway"	"Glutathione synthesis and recycling; NFE2L2 regulating anti-oxidant/detoxification enzymes; Defective GCLC causes HAGGSD"	"14"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVF2"	"Protein AHNAK2 OS=Homo sapiens OX=9606 GN=AHNAK2 PE=1 SV=2"	"0.000"	""	"0"	"1"	"2"	"1"	"5795"	"616.2"	"5.36"	"358.67"	"3.54"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	""	"113146"	"ENSG00000185567"	"AHNAK2"	"hsa:113146; Q5BKX7; Q7Z343; Q7Z358; Q7Z394; Q7Z3G0; Q86WQ6; Q8IVF2; Q8IYY1; Q8N3G4; Q96EX9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53992"	"Protein transport protein Sec24C OS=Homo sapiens OX=9606 GN=SEC24C PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1094"	"118.2"	"7.06"	"318.51"	"3.54"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes"	"other membranes;cytosol;ER/Golgi"	"other molecular function"	"Pf00626, Pf04810, Pf04811, Pf04815, Pf08033"	"9632"	"ENSG00000176986"	"SEC24C"	"B4DZT4; hsa:9632; P53992; Q8WV25"	"Sterol regulatory element-binding proteins (SREBP) signaling"	"COPII-mediated vesicle transport; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Cargo concentration in the ER; Regulation of cholesterol biosynthesis by SREBP (SREBF)"	"7"	"0"	"16.0"	"14.7"	"20.4"	"22.8"	"21.6"	"13.8"	"31.2"	"28.4"	"53.1"	"129.3"	"230.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P49841"	"Glycogen synthase kinase-3 beta OS=Homo sapiens OX=9606 GN=GSK3B PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"420"	"46.7"	"8.78"	""	"3.54"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"2932"	"ENSG00000082701"	"GSK3B"	"D3DN89; hsa:2932; P49841; Q9BWH3; Q9UL47"	"IL-5 signaling pathway; Androgen receptor signaling pathway; Energy metabolism; MicroRNAs in cardiomyocyte hypertrophy; Cell cycle; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; IL-17 signaling pathway; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Cardiac progenitor differentiation; T cell receptor and co-stimulatory signaling; Cardiac hypertrophic response; Focal adhesion; Copper homeostasis; Melatonin metabolism and effects; Wnt signaling pathway; IL6 signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Physico-chemical features and toxicity-associated pathways; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Regulation of apoptosis by parathyroid hormone-related protein; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K/AKT/mTOR - vitamin D3 signaling; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; Acute viral myocarditis; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; NRF2-ARE regulation; Nonalcoholic fatty liver disease; Synaptic signaling pathways associated with autism spectrum disorder; Gastrin signaling pathway; Thyroid hormones production and peripheral downstream signaling effects; IL-18 signaling pathway; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Influence of laminopathies on Wnt signaling; MAP3K1 role in promoting and blocking gonadal determination; Overlap between signal transduction pathways contributing to LMNA laminopathies; Glycogen synthesis and degradation; Pleural mesothelioma; CCL18 signaling pathway; Alzheimer's disease; GDNF signaling; DYRK1A involvement regarding cell proliferation in brain development; Neurogenesis regulation in the olfactory epithelium; Sildenafil treatment; A network map of Macrophage-stimulating protein (MSP) signaling; Notch signaling pathway; ErbB signaling pathway; DNA damage response (only ATM dependent)"	"Regulation of HSF1-mediated heat shock response; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Ubiquitin-dependent degradation of Cyclin D; Regulation of RUNX2 expression and activity; Constitutive Signaling by AKT1 E17K in Cancer; B-WICH complex positively regulates rRNA expression; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; CRMPs in Sema3A signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; AKT phosphorylates targets in the cytosol; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein; Maturation of nucleoprotein"	"93"	"0"	"20.9"	"18.6"	"27.5"	"24.8"	"21.9"	"26.2"	"33.4"	"31.7"	"45.4"	"85.8"	"105.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13596"	"Sorting nexin-1 OS=Homo sapiens OX=9606 GN=SNX1 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"522"	"59.0"	"5.15"	""	"3.54"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf03700, Pf09325"	"6642"	"ENSG00000028528"	"SNX1"	"A6NM19; A8K6T7; H0Y2M5; hsa:6642; O60750; O60751; Q13596; Q6ZRJ8"	""	""	"0"	"0"	"5.4"	"3.1"	"2.3"	"7.3"	"1.8"	"3.7"	"10.8"	"10.3"	"14.8"	"63.2"	"210.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30622"	"CAP-Gly domain-containing linker protein 1 OS=Homo sapiens OX=9606 GN=CLIP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1438"	"162.1"	"5.36"	"352.56"	"3.53"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01302, Pf16641"	"6249"	"ENSG00000130779"	"CLIP1"	"A0AVD3; hsa:6249; P30622; Q17RS4; Q29RG0"	"Microtubule cytoskeleton regulation; PAFAH1B1 copy number variation"	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases activate IQGAPs; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"9.5"	"12.5"	"16.4"	"16.3"	"15.3"	"11.2"	"17.8"	"20.0"	"27.4"	"68.0"	"111.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P86790"	"Vacuolar fusion protein CCZ1 homolog B OS=Homo sapiens OX=9606 GN=CCZ1B PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"482"	"55.8"	"6.48"	""	"3.53"	""	"1"	"transport"	"other membranes;other cytoplasmic organelle;other cell component"	""	"Pf19031, Pf19032, Pf19033"	"221960; 51622"	"ENSG00000146574"	"CCZ1B"	"A2RU45; hsa:221960; hsa:51622; O95766; P86790; Q9UG65; Q9Y359"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"14.8"	"13.2"	"13.3"	"17.1"	"20.3"	"13.4"	"24.1"	"27.6"	"33.9"	"83.9"	"98.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P266"	"Junctional protein associated with coronary artery disease OS=Homo sapiens OX=9606 GN=JCAD PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"1359"	"148.3"	"7.09"	"874.88"	"3.53"	"2"	"1"	"cell adhesion;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf15351"	"57608"	"ENSG00000165757"	"JCAD"	"hsa:57608; Q5HYA7; Q5T992; Q86WZ9; Q9BYJ2; Q9P266"	""	""	"0"	"0"	"35.2"	"27.7"	"39.2"	"48.4"	"32.3"	"30.8"	"60.0"	"61.4"	"101.3"	"189.4"	"260.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13492"	"Phosphatidylinositol-binding clathrin assembly protein OS=Homo sapiens OX=9606 GN=PICALM PE=1 SV=2"	"0.000"	""	"5"	"2"	"3"	"2"	"652"	"70.7"	"7.90"	"810.64"	"3.52"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf07651"	"8301"	"ENSG00000073921"	"PICALM"	"B4DTM3; E9PN05; F8VPG7; hsa:8301; O60700; Q13492; Q4LE54; Q6GMQ6; Q86XZ9"	""	"Cargo recognition for clathrin-mediated endocytosis; Golgi Associated Vesicle Biogenesis; RND3 GTPase cycle"	"4"	"0"	"119.7"	"81.5"	"114.7"	"112.9"	"114.9"	"133.7"	"189.5"	"209.9"	"268.5"	"519.5"	"808.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13501"	"Sequestosome-1 OS=Homo sapiens OX=9606 GN=SQSTM1 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"440"	"47.7"	"5.22"	""	"3.52"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf00564, Pf00569, Pf16577"	"8878"	"ENSG00000161011; ENSG00000284099"	"SQSTM1"	"A6NFN7; B2R661; B3KUW5; hsa:8878; Q13446; Q13501; Q9BUV7; Q9BVS6; Q9UEU1"	"IL-1 signaling pathway; RANKL/RANK signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; Nuclear receptors meta-pathway; NRF2 pathway; Interleukin-1 induced activation of NF-kB; Clear cell renal cell carcinoma pathways; CAMKK2 pathway; 7q11.23 copy number variation syndrome; Opioid receptor pathways; Clock-controlled autophagy in bone metabolism; Autophagy in pancreatic ductal adenocarcinoma"	"Neddylation; Interleukin-1 signaling; Signaling by ALK fusions and activated point mutants; p75NTR recruits signalling complexes; NF-kB is activated and signals survival; Nuclear events mediated by NFE2L2; PINK1-PRKN Mediated Mitophagy; NRIF signals cell death from the nucleus; Pexophagy"	"23"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TC92"	"Ecto-NOX disulfide-thiol exchanger 1 OS=Homo sapiens OX=9606 GN=ENOX1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"643"	"73.3"	"5.54"	"350.68"	"3.52"	"1"	"1"	"other biological processes"	"non-structural extracellular;plasma membrane;other membranes"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"55068"	"ENSG00000120658"	"ENOX1"	"A4GU15; A6NMH9; B7Z5K1; hsa:55068; Q2TU81; Q5VT11; Q8TC92; Q9NWE0"	""	""	"0"	"0"	"9.2"	"7.5"	"11.7"	"11.8"	"6.5"	"11.5"	"15.3"	"13.7"	"17.6"	"32.7"	"41.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00299"	"Chloride intracellular channel protein 1 OS=Homo sapiens OX=9606 GN=CLIC1 PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"241"	"26.9"	"5.17"	"367.99"	"3.51"	"1"	"1"	"transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;mitochondrion;nucleus;other cell component"	"transporter activity"	"Pf13409, Pf13410"	"1192"	"ENSG00000206394; ENSG00000213719; ENSG00000223639; ENSG00000226248; ENSG00000226417; ENSG00000226651; ENSG00000230685"	"CLIC1"	"hsa:1192; O00299; Q15089; Q502X1"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"8.5"	"4.2"	"24.9"	"42.5"	"15.7"	"10.7"	"25.6"	"24.2"	"31.8"	"64.4"	"144.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99442"	"Translocation protein SEC62 OS=Homo sapiens OX=9606 GN=SEC62 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"399"	"45.8"	"7.12"	"399.75"	"3.51"	"1"	"1"	"transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03839"	"7095"	"ENSG00000008952"	"SEC62"	"D3DNQ0; hsa:7095; O00682; O00729; Q99442"	""	""	"0"	"0"	"20.0"	"15.2"	"19.2"	"27.4"	"31.3"	"27.9"	"51.8"	"47.3"	"89.0"	"371.9"	"508.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11216"	"Glycogen phosphorylase, brain form OS=Homo sapiens OX=9606 GN=PYGB PE=1 SV=5"	"0.000"	""	"2"	"1"	"2"	"1"	"843"	"96.6"	"6.86"	"314.47"	"3.51"	"1"	"1"	"other metabolic processes"	"non-structural extracellular;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00343"	"5834"	"ENSG00000100994"	"PYGB"	"hsa:5834; P11216; Q96AK1; Q9NPX8"	"IL-18 signaling pathway; Glycogen synthesis and degradation"	"Neutrophil degranulation; Glycogen breakdown (glycogenolysis)"	"4"	"0"	"12.0"	"7.8"	"14.2"	"25.9"	"14.3"	"11.0"	"21.6"	"23.3"	"31.8"	"78.7"	"125.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15154"	"Pericentriolar material 1 protein OS=Homo sapiens OX=9606 GN=PCM1 PE=1 SV=5"	"0.000"	""	"1"	"1"	"2"	"1"	"2024"	"228.4"	"5.02"	"318.41"	"3.51"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf15717"	"5108"	"ENSG00000078674"	"PCM1"	"A6NNN6; B4DYD5; E7ETA6; E7EV56; hsa:5108; Q15154; Q58F13; Q6P1K7; Q8NB85; Q9BWC1; Q9H4A2"	"Prader-Willi and Angelman syndrome; Joubert syndrome"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"9"	"0"	"13.1"	"8.6"	"8.9"	"11.7"	"10.5"	"10.0"	"13.3"	"14.8"	"21.4"	"33.4"	"58.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18887"	"DNA repair protein XRCC1 OS=Homo sapiens OX=9606 GN=XRCC1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"633"	"69.4"	"6.39"	"427.15"	"3.50"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"29.0"	"31.4"	"41.0"	"41.8"	"30.7"	"28.8"	"50.1"	"46.8"	"56.9"	"138.0"	"309.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P41208"	"Centrin-2 OS=Homo sapiens OX=9606 GN=CETN2 PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"172"	"19.7"	"5.00"	"393.61"	"3.50"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13499"	"1069"	"ENSG00000147400"	"CETN2"	"B2R4T4; hsa:1069; P41208; Q53XW1"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2; SUMOylation of DNA damage response and repair proteins; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER"	"13"	"0"	"39.9"	"27.3"	"43.6"	"42.4"	"43.2"	"40.6"	"97.7"	"93.4"	"110.4"	"205.7"	"257.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NBT2"	"Kinetochore protein Spc24 OS=Homo sapiens OX=9606 GN=SPC24 PE=1 SV=2"	""	""	"14"	"1"	"1"	"1"	"197"	"22.5"	"4.70"	""	"3.49"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P05783"	"Keratin, type I cytoskeletal 18 OS=Homo sapiens OX=9606 GN=KRT18 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"1"	"430"	"48.0"	"5.45"	"627.91"	"3.49"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00038"	"3875"	"ENSG00000111057"	"KRT18"	"hsa:3875; P05783; Q53G38; Q5U0N8; Q9BW26"	"Pathogenic Escherichia coli infection"	"Formation of the cornified envelope"	"3"	"0"	"21.1"	"22.1"	"20.4"	"33.8"	"15.6"	"23.2"	"41.5"	"55.5"	"66.6"	"213.0"	"274.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49916"	"DNA ligase 3 OS=Homo sapiens OX=9606 GN=LIG3 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"1009"	"112.8"	"9.01"	"1048.40"	"3.49"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"mitochondrion;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00645, Pf01068, Pf04675, Pf04679, Pf16759"	"3980"	"ENSG00000005156"	"LIG3"	"E5KLB5; E5KLB6; hsa:3980; P49916; Q16714; Q6NVK3"	"Base excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; 17q12 copy number variation syndrome"	"HDR through MMEJ (alt-NHEJ); Gap-filling DNA repair synthesis and ligation in TC-NER; Gap-filling DNA repair synthesis and ligation in GG-NER; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; Resolution of AP sites via the single-nucleotide replacement pathway"	"9"	"0"	"68.8"	"53.1"	"77.9"	"94.1"	"61.6"	"74.4"	"138.2"	"143.9"	"229.8"	"600.7"	"1047.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5J1"	"U3 small nucleolar RNA-associated protein 18 homolog OS=Homo sapiens OX=9606 GN=UTP18 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"556"	"62.0"	"8.76"	"524.03"	"3.49"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	""	""	"51096"	"ENSG00000011260"	"UTP18"	"hsa:51096; Q9H4N6; Q9Y5J1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"42.7"	"52.1"	"47.9"	"46.0"	"43.2"	"42.5"	"52.6"	"58.2"	"70.4"	"115.8"	"120.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96TC7"	"Regulator of microtubule dynamics protein 3 OS=Homo sapiens OX=9606 GN=RMDN3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"470"	"52.1"	"5.10"	"320.63"	"3.49"	"1"	"1"	"other biological processes"	"other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity"	""	"55177"	"ENSG00000137824"	"RMDN3"	"A9UMZ9; B3KRR3; hsa:55177; Q6ZWE9; Q96H23; Q96SD6; Q96TC7; Q9H6G1; Q9NVQ6"	""	""	"0"	"0"	"77.4"	"73.2"	"92.1"	"115.1"	"75.9"	"77.6"	"115.1"	"99.8"	"150.4"	"315.1"	"471.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96PV6"	"Leukocyte receptor cluster member 8 OS=Homo sapiens OX=9606 GN=LENG8 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"800"	"88.1"	"9.11"	""	"3.49"	""	"1"	""	"nucleus;other cell component"	""	"Pf03399"	"114823"	"ENSG00000167615; ENSG00000274305; ENSG00000276458; ENSG00000276681"	"LENG8"	"A0A087WTE7; B0VJY9; hsa:114823; Q8IZ27; Q8NCX6; Q96PV6"	""	""	"0"	"0"	"79.2"	"69.1"	"82.1"	"97.4"	"75.2"	"62.5"	"101.8"	"118.2"	"150.9"	"391.8"	"673.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEF9"	"Serum response factor-binding protein 1 OS=Homo sapiens OX=9606 GN=SRFBP1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"429"	"48.6"	"9.58"	"356.93"	"3.48"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf09073"	"153443"	"ENSG00000151304"	"SRFBP1"	"hsa:153443; Q5QFI2; Q8NEF9; Q96AH4; Q96DK2"	""	""	"0"	"0"	"15.0"	"12.3"	"17.5"	"16.0"	"13.0"	"17.0"	"19.0"	"18.2"	"25.7"	"59.3"	"75.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBF8"	"Phosphatidylinositol 4-kinase beta OS=Homo sapiens OX=9606 GN=PI4KB PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"816"	"91.3"	"6.25"	"450.33"	"3.48"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;signal transduction"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00454"	"5298"	"ENSG00000143393"	"PI4KB"	"B4DGI2; hsa:5298; O15096; P78405; Q5VWB9; Q5VWC0; Q5VWC1; Q9BWR6; Q9UBF8"	""	"Synthesis of PIPs at the Golgi membrane"	"1"	"0"	"10.9"	"9.4"	"4.6"	"7.6"	"4.7"	"7.1"	"14.3"	"11.3"	"20.5"	"66.4"	"79.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWB1"	"RNA binding protein fox-1 homolog 1 OS=Homo sapiens OX=9606 GN=RBFOX1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"397"	"42.8"	"6.86"	"371.58"	"3.48"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12414"	"54715"	"ENSG00000078328"	"RBFOX1"	"hsa:54715; Q7Z7I7; Q8TAE3; Q8TAF2; Q8WYB2; Q9NS20; Q9NWB1"	"MECP2 and associated Rett syndrome"	"MECP2 regulates transcription factors"	"2"	"0"	"32.3"	"32.7"	"46.1"	"59.2"	"43.8"	"43.9"	"64.0"	"59.8"	"75.6"	"178.2"	"236.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35226"	"Polycomb complex protein BMI-1 OS=Homo sapiens OX=9606 GN=BMI1 PE=1 SV=2"	"0.001"	""	"6"	"2"	"2"	"2"	"326"	"36.9"	"8.63"	"243.42"	"3.48"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf13923, Pf16207"	"100532731; 648"	"ENSG00000168283"	"BMI1"	"hsa:100532731; hsa:648; P35226; Q16030; Q5T8Z3; Q96F37"	"Pleural mesothelioma; Interactions of natural killer cells in pancreatic cancer; CCL18 signaling pathway"	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transcriptional Regulation by E2F6; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"12"	"0"	"73.4"	"76.4"	"84.1"	"129.4"	"57.2"	"52.2"	"168.1"	"171.7"	"294.4"	"751.8"	"882.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N1B4"	"Vacuolar protein sorting-associated protein 52 homolog OS=Homo sapiens OX=9606 GN=VPS52 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"723"	"82.2"	"5.99"	"370.01"	"3.47"	"1"	"1"	"transport;developmental processes;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04129"	"6293"	"ENSG00000206286; ENSG00000223501; ENSG00000224455; ENSG00000225590; ENSG00000228425; ENSG00000236014"	"VPS52"	"A2BF38; B0UZZ4; B4DNI9; hsa:6293; Q53GR4; Q5JPA0; Q5SQW1; Q8IUN6; Q8N1B4; Q9NPT5"	""	"Retrograde transport at the Trans-Golgi-Network"	"1"	"0"	"22.0"	"15.8"	"23.5"	"19.2"	"14.3"	"27.1"	"37.3"	"27.5"	"38.0"	"80.5"	"106.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75312"	"Zinc finger protein ZPR1 OS=Homo sapiens OX=9606 GN=ZPR1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"459"	"50.9"	"4.73"	"397.54"	"3.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03367"	"8882"	"ENSG00000109917"	"ZPR1"	"hsa:8882; O75312; Q2TAA0"	""	""	"0"	"0"	"114.7"	"106.4"	"116.8"	"120.2"	"107.3"	"106.1"	"152.2"	"162.5"	"179.0"	"419.3"	"641.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NZ56"	"Formin-2 OS=Homo sapiens OX=9606 GN=FMN2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1722"	"180.0"	"5.47"	""	"3.47"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity"	"Pf02181"	"56776"	"ENSG00000155816"	"FMN2"	"B0QZA7; B4DP05; hsa:56776; Q59GF6; Q5VU37; Q9NZ55; Q9NZ56"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14137"	"Ribosome biogenesis protein BOP1 OS=Homo sapiens OX=9606 GN=BOP1 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"746"	"83.6"	"6.19"	"891.17"	"3.47"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf08145"	"23246"	"ENSG00000261236; ENSG00000285301"	"BOP1"	"hsa:23246; Q14137; Q969Z6; Q96IS8; Q96Q25; Q9BSA7; Q9BVM0"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"67.3"	"83.3"	"80.9"	"74.5"	"63.1"	"56.8"	"87.7"	"88.2"	"90.8"	"170.9"	"274.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYI3"	"Hyccin OS=Homo sapiens OX=9606 GN=FAM126A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"521"	"57.6"	"8.16"	"345.14"	"3.47"	"1"	"1"	"other metabolic processes;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09790"	"84668"	"ENSG00000122591"	"HYCC1"	"A0A024RA06; A4D145; B8ZZJ1; hsa:84668; Q6N010; Q75MR4; Q7LDZ4; Q96MX1; Q96NQ6; Q9BYI3"	""	""	"0"	"0"	"66.8"	"58.2"	"72.5"	"90.0"	"56.4"	"69.7"	"159.4"	"171.5"	"313.3"	"656.2"	"739.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TAX3"	"Terminal uridylyltransferase 4 OS=Homo sapiens OX=9606 GN=TUT4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1644"	"185.0"	"7.97"	"332.78"	"3.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00098, Pf01909, Pf03828, Pf19088"	"23318"	"ENSG00000134744"	"TUT4"	"A2RRP0; B7Z8J5; D3DQ35; hsa:23318; Q12764; Q5TAX2; Q5TAX3; Q5TAX4; Q86XZ3"	""	"Deadenylation of mRNA"	"1"	"0"	"14.3"	"12.7"	"17.5"	"20.9"	"13.0"	"16.5"	"23.0"	"27.2"	"39.4"	"94.9"	"106.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q03164"	"Histone-lysine N-methyltransferase 2A OS=Homo sapiens OX=9606 GN=KMT2A PE=1 SV=5"	"0.000"	""	"0"	"1"	"2"	"1"	"3969"	"431.5"	"9.09"	"351.93"	"3.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf00856, Pf02008, Pf05964, Pf05965, Pf13771"	"4297"	"ENSG00000118058"	"KMT2A"	"E9PQG7; hsa:4297; Q03164; Q13743; Q13744; Q14845; Q16364; Q59FF2; Q6UBD1; Q9HBJ3; Q9UD94; Q9UMA3"	"Histone modifications"	"RUNX1 regulates transcription of genes involved in differentiation of HSCs; Formation of WDR5-containing histone-modifying complexes; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Transcriptional regulation of granulopoiesis; PKMTs methylate histone lysines"	"6"	"0"	"34.5"	"32.4"	"46.1"	"48.3"	"41.3"	"37.1"	"71.9"	"87.2"	"138.1"	"298.7"	"405.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q56NI9"	"N-acetyltransferase ESCO2 OS=Homo sapiens OX=9606 GN=ESCO2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"601"	"68.3"	"9.39"	"302.91"	"3.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf13878, Pf13880"	"157570"	"ENSG00000171320"	"ESCO2"	"B3KW59; hsa:157570; Q49AP4; Q56NI9"	"Cohesin complex - Cornelia de Lange syndrome"	"Establishment of Sister Chromatid Cohesion"	"2"	"0"	"39.4"	"49.2"	"46.1"	"75.0"	"35.8"	"30.5"	"79.9"	"94.4"	"109.5"	"211.4"	"305.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQS7"	"Inner centromere protein OS=Homo sapiens OX=9606 GN=INCENP PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"918"	"105.4"	"9.44"	"266.83"	"3.46"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf03941, Pf12178"	"3619"	"ENSG00000149503"	"INCENP"	"A8MQD2; hsa:3619; Q5Y192; Q9NQS7"	""	"SUMOylation of DNA replication proteins; RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"7"	"0"	"34.1"	"29.2"	"48.3"	"52.8"	"36.5"	"21.9"	"64.3"	"61.4"	"71.4"	"149.2"	"185.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWZ8"	"SURP and G-patch domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SUGP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"645"	"72.4"	"7.61"	"291.88"	"3.46"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf01585, Pf01805"	"57794"	"ENSG00000105705"	"SUGP1"	"hsa:57794; O60378; Q6P3X9; Q8IWZ8; Q8TCQ4; Q8WWT4; Q8WWT5; Q9NTG3"	"mRNA processing"	"mRNA Splicing - Major Pathway"	"2"	"0"	"76.2"	"62.8"	"87.4"	"91.3"	"80.1"	"69.6"	"99.2"	"109.2"	"118.5"	"201.8"	"282.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZ32"	"Actin-related protein 10 OS=Homo sapiens OX=9606 GN=ACTR10 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"417"	"46.3"	"7.37"	"343.42"	"3.45"	"1"	"1"	"transport"	"non-structural extracellular;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	""	"Pf00022"	"55860"	"ENSG00000131966"	"ACTR10"	"hsa:55860; Q9H9Y5; Q9NWY2; Q9NZ32"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Neutrophil degranulation"	"5"	"0"	"8.5"	"9.5"	"10.9"	"13.3"	"10.1"	"10.5"	"15.3"	"20.1"	"29.8"	"62.1"	"80.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VZ89"	"DENN domain-containing protein 4C OS=Homo sapiens OX=9606 GN=DENND4C PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1909"	"212.6"	"6.83"	"381.24"	"3.44"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity"	"Pf02141, Pf03455, Pf03456"	"55667"	"ENSG00000137145"	"DENND4C"	"A2A3R1; A2A3R2; A2A3R3; A2A3R9; hsa:55667; Q5VZ89; Q6AI48; Q6ZUB3; Q8NCY7; Q9H6N4; Q9NUT1; Q9NWA5; Q9NWT3; R4GN35; R4GNB2"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"19.0"	"20.7"	"19.2"	"34.5"	"25.7"	"21.9"	"28.8"	"29.2"	"47.0"	"112.2"	"168.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IV0"	"Peptide-N(4)-(N-acetyl-beta-glucosaminyl)asparagine amidase OS=Homo sapiens OX=9606 GN=NGLY1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"654"	"74.3"	"6.89"	"267.39"	"3.44"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01841, Pf04721, Pf09409"	"55768"	"ENSG00000151092"	"NGLY1"	"B4DJE9; hsa:55768; Q59FB1; Q6PJD8; Q96IV0; Q9BVR8; Q9NR70"	""	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"1"	"0"	"10.9"	"7.0"	"13.8"	"12.5"	"8.3"	"9.8"	"12.3"	"16.0"	"18.5"	"58.2"	"90.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0E2"	"Toll-interacting protein OS=Homo sapiens OX=9606 GN=TOLLIP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"274"	"30.3"	"5.97"	"391.48"	"3.44"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00168, Pf02845"	"54472"	"ENSG00000078902"	"TOLLIP"	"B3KXC6; hsa:54472; Q9H0E2; Q9H9E6; Q9UJ69"	"IL-1 signaling pathway; Interleukin-1 (IL-1) structural pathway; Toll-like receptor signaling related to MyD88; Signal transduction through IL1R; Toll-like receptor signaling pathway"	"Neutrophil degranulation; Interleukin-1 signaling"	"7"	"0"	"44.2"	"45.6"	"91.0"	"82.2"	"51.8"	"53.8"	"106.3"	"120.6"	"172.3"	"502.1"	"628.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08237"	"ATP-dependent 6-phosphofructokinase, muscle type OS=Homo sapiens OX=9606 GN=PFKM PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"780"	"85.1"	"7.99"	"307.28"	"3.44"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"kinase activity;other molecular function"	"Pf00365"	"5213"	"ENSG00000152556"	"PFKM"	"hsa:5213; J3KNX3; P08237; Q16814; Q16815; Q6ZTT1"	"Clear cell renal cell carcinoma pathways; Aerobic glycolysis; Insulin signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Glycolysis"	"6"	"0"	"48.8"	"42.0"	"51.2"	"63.1"	"45.5"	"42.4"	"79.9"	"78.0"	"103.7"	"163.3"	"202.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5HYJ3"	"Protein FAM76B OS=Homo sapiens OX=9606 GN=FAM76B PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"339"	"38.7"	"9.25"	""	"3.43"	""	"1"	""	"nucleus"	""	"Pf16046"	"143684"	"ENSG00000077458"	"FAM76B"	"B2R9C2; hsa:143684; Q5HYJ3; Q6PIU3; Q8TC53"	""	""	"0"	"0"	"66.3"	"82.4"	"68.4"	"123.4"	"71.0"	"36.7"	"145.5"	"172.4"	"229.0"	"380.8"	"328.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BXW9"	"Fanconi anemia group D2 protein OS=Homo sapiens OX=9606 GN=FANCD2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1451"	"164.0"	"5.88"	"340.24"	"3.43"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14631"	"2177"	"ENSG00000144554"	"FANCD2"	"hsa:2177; Q2LA86; Q69YP9; Q6PJN7; Q9BQ06; Q9BXW9; Q9H9T9"	"miRNA regulation of DNA damage response; 15q13.3 copy number variation syndrome; DNA repair pathways, full network; 15q11q13 copy number variation; DNA damage response"	"TP53 Regulates Transcription of DNA Repair Genes; Fanconi Anemia Pathway"	"7"	"0"	"5.6"	"9.9"	"11.7"	"14.9"	"9.5"	"6.6"	"17.0"	"15.6"	"32.7"	"112.7"	"144.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN4"	"Centrosomal protein of 131 kDa OS=Homo sapiens OX=9606 GN=CEP131 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1083"	"122.1"	"8.69"	"285.30"	"3.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	""	"22994"	"ENSG00000141577"	"CEP131"	"A6NHI8; B2RN11; hsa:22994; Q96F50; Q9UPN4"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"10.4"	"8.2"	"18.9"	"20.5"	"11.1"	"13.2"	"27.1"	"20.6"	"38.0"	"70.2"	"93.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWU2"	"Glucose-induced degradation protein 8 homolog OS=Homo sapiens OX=9606 GN=GID8 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"228"	"26.7"	"4.97"	"300.16"	"3.42"	"1"	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08513, Pf10607"	"54994"	"ENSG00000101193"	"GID8"	"E1P5I3; hsa:54994; Q8N5M5; Q9NWU2"	"Ciliary landscape"	""	"1"	"0"	"12.7"	"13.9"	"17.8"	"22.5"	"18.7"	"17.8"	"32.6"	"41.1"	"67.2"	"175.7"	"231.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16625"	"Occludin OS=Homo sapiens OX=9606 GN=OCLN PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"522"	"59.1"	"6.09"	"365.55"	"3.42"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01284, Pf07303"	"100506658"	"ENSG00000197822"	"OCLN"	"B5BU70; D2DU64; D2DU65; D2IGC0; D2IGC1; E2CYV9; hsa:100506658; Q16625; Q5U1V4; Q8N6K1"	"Pathogenic Escherichia coli infection; VEGFA-VEGFR2 signaling; Epithelial to mesenchymal transition in colorectal cancer; 1q21.1 copy number variation syndrome; CKAP4 signaling pathway map; 15q11q13 copy number variation"	"RUNX1 regulates expression of components of tight junctions; Apoptotic cleavage of cell adhesion  proteins"	"8"	"0"	"33.5"	"41.1"	"32.8"	"44.7"	"35.0"	"41.8"	"63.2"	"73.5"	"97.1"	"290.4"	"386.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07864"	"DNA polymerase epsilon catalytic subunit A OS=Homo sapiens OX=9606 GN=POLE PE=1 SV=5"	"0.000"	""	"1"	"1"	"2"	"1"	"2286"	"261.4"	"6.39"	"282.46"	"3.42"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;developmental processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00136, Pf03104, Pf08490"	"5426"	"ENSG00000177084"	"POLE"	"hsa:5426; Q07864; Q13533; Q86VH9"	"Retinoblastoma gene in cancer; Pyrimidine metabolism; G1 to S cell cycle control; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"19"	"0"	"8.4"	"14.5"	"11.8"	"10.6"	"10.7"	"13.9"	"21.1"	"20.7"	"26.5"	"82.1"	"113.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWV7"	"E3 ubiquitin-protein ligase UBR1 OS=Homo sapiens OX=9606 GN=UBR1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1749"	"200.1"	"6.01"	"301.49"	"3.41"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf02207, Pf02617, Pf18995"	"197131"	"ENSG00000159459"	"UBR1"	"hsa:197131; O60708; O75492; Q14D45; Q68DN9; Q8IWV7; Q8IWY6; Q96JY4"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"12.8"	"18.9"	"14.3"	"18.6"	"14.8"	"8.8"	"18.3"	"18.9"	"28.3"	"52.8"	"83.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92830"	"Histone acetyltransferase KAT2A OS=Homo sapiens OX=9606 GN=KAT2A PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"837"	"93.9"	"9.04"	"332.87"	"3.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00583, Pf06466"	"2648"	"ENSG00000108773"	"KAT2A"	"hsa:2648; Q8N1A2; Q92830; Q9UCW1"	"Notch signaling"	"Ub-specific processing proteases; B-WICH complex positively regulates rRNA expression; Pre-NOTCH Transcription and Translation; HATs acetylate histones; Formation of paraxial mesoderm; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Formation of WDR5-containing histone-modifying complexes; RNA Polymerase I Transcription Initiation; Cardiogenesis; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; NOTCH3 Intracellular Domain Regulates Transcription; Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells; NOTCH4 Intracellular Domain Regulates Transcription; RUNX3 regulates NOTCH signaling"	"17"	"0"	"0.0"	"0.0"	"3.2"	"0.0"	"2.5"	"0.0"	"5.4"	"10.4"	"15.1"	"65.3"	"53.2"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9GZM8"	"Nuclear distribution protein nudE-like 1 OS=Homo sapiens OX=9606 GN=NDEL1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"345"	"38.4"	"5.24"	"549.48"	"3.41"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04880"	"81565"	"ENSG00000166579"	"NDEL1"	"B3KP93; D3DTS0; hsa:81565; J3QT32; Q86T80; Q8TAR7; Q9GZM8; Q9UH50"	"Neurogenesis regulation in the olfactory epithelium; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"8"	"0"	"24.6"	"20.1"	"37.8"	"42.0"	"32.2"	"19.0"	"48.1"	"51.6"	"71.7"	"128.8"	"195.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWJ5"	"Splicing factor 3B subunit 5 OS=Homo sapiens OX=9606 GN=SF3B5 PE=1 SV=1"	"0.000"	""	"17"	"1"	"2"	"1"	"86"	"10.1"	"6.35"	"329.90"	"3.41"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07189"	"83443"	"ENSG00000169976"	"SF3B5"	"B2R568; hsa:83443; Q7RTV1; Q9BWJ5"	"mRNA processing"	"mRNA Splicing - Major Pathway; mRNA Splicing - Minor Pathway"	"3"	"0"	"22.9"	"30.5"	"39.1"	"41.1"	"34.1"	"33.0"	"45.5"	"43.5"	"46.6"	"98.5"	"154.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFI3"	"Cytosolic endo-beta-N-acetylglucosaminidase OS=Homo sapiens OX=9606 GN=ENGASE PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"743"	"83.9"	"6.79"	"402.88"	"3.41"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf03644"	"64772"	"ENSG00000167280"	"ENGASE"	"hsa:64772; Q659F0; Q8NFI3; Q8TB86; Q9H6U4"	""	"N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"1"	"0"	"20.1"	"15.4"	"21.1"	"26.9"	"19.4"	"22.8"	"46.0"	"64.4"	"106.3"	"235.3"	"228.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75367"	"Core histone macro-H2A.1 OS=Homo sapiens OX=9606 GN=MACROH2A1 PE=1 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"372"	"39.6"	"9.79"	"306.38"	"3.40"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00125, Pf01661, Pf16211"	"100394084; 100998964; 101131222; 101381952; 101564704; 101706296; 102008188; 102123677; 103079324; 104855290; 105467125; 105506940; 105531308; 105816031; 105869993; 108529540; 462076; 481514; 711836"	"ENSAMEG00000017887; ENSBMSG00010001156; ENSCAFG00000001076; ENSCAFG00020007175; ENSCAFG00030007355; ENSCAFG00040009734; ENSCANG00000022762; ENSCJAG00000005818; ENSCLAG00000016530; ENSCWAG00000001657; ENSFCAG00000013924; ENSGGOG00000001707; ENSLCNG00005003680; ENSMICG00000005677; ENSMLEG00000037795; ENSMMNG00015002866; ENSMNEG00000031666; ENSMPUG00000010011; ENSPANG00000002758; ENSPCOG00000013464; ENSPCTG00005011747; ENSPLOG00000000479; ENSPPAG00000029258; ENSPPYG00000015799; ENSPSMG00000021213; ENSPSNG00000019193; ENSPTRG00000017256; ENSRBIG00000034425; ENSRROG00000045755; ENSSBOG00000034640; ENSSSUG00005001976; ENSSVLG00005008251; ENSTGEG00000021330; ENSVVUG00000017487"	"H2afy; H2AFY; LOC100466888; LOC101338325; LOC101381952; LOC101564704; LOC102987354; LOC103079324; LOC103663804; LOC105869993; LOC106989149; LOC110591142; LOC111141291; LOC111182462; LOC112404331; LOC112625777; LOC112815157; LOC112861289; LOC112917035; LOC113928700; LOC114891795; LOC115516119; LOC116529369; LOC116750637; MACROH2A1"	"A0A091CNU6; A0A096N0E8; A0A2J8LRK8; A0A2J8VQ67; A0A2K5HRC8; A0A2K5W7N1; A0A2K5ZHE4; A0A2K6BUT6; A0A2K6EU20; A0A2K6LBL0; A0A2K6RXM8; A0A2K6UYW1; A0A2R9A926; A0A2U3WAW1; A0A2Y9IU30; A0A2Y9PFA0; A0A2Y9SS16; A0A340XJ26; A0A341BZA5; A0A3Q7NDG6; A0A3Q7S763; A0A484GVZ9; A0A485NYK5; A0A5S6R987; A0A667GC30; A0A673T0D7; A0A6G1ASZ6; A0A6J2AVA7; A0A6J2DX40; A0A6J3FC37; A0A6J3R528; A0A6P3F5E4; A0A6P6HX24; A0A8B7G616; A0A8C0C880; A0A8C0K484; A0A8C0S4U0; A0A8C2W4Z6; A0A8C3VQP8; A0A8C6F240; A0A8C8WAC0; A0A8C9AAB1; A0A8C9CK62; A0A8D2BC14; A0A8D2FWT2; A0A8I5UBU0; A0A8J8XTA7; A0A8M1F844; A0A8M1MQV0; A0A8P0N4A7; aju:106989149; cang:105506940; D2GVK3; dle:111182462; elk:111141291; F7HN69; G3QH59; G5BQ26; G7MUD7; ggo:101131222; H2QRI8; I2CUE9; lve:103079324; M3WJR3; M3YF29; mcf:102123677; mleu:105531308; mmur:105869993; mni:105467125; mpuf:101692673; nsu:110591142; oro:101381952; panu:100998964; pcad:102987354; pcoq:105816031; ptr:462076; rbb:108529540; sbq:101050376; umr:103663804; vvp:112917035; zca:113928700"	""	""	"0"	"0"	"45.4"	"41.3"	"71.6"	"83.1"	"56.6"	"50.9"	"89.3"	"89.5"	"140.7"	"271.0"	"392.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14677"	"Clathrin interactor 1 OS=Homo sapiens OX=9606 GN=CLINT1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"625"	"68.2"	"6.42"	"347.29"	"3.40"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01417"	"9685"	"ENSG00000113282"	"CLINT1"	"B7Z6F8; D3DQJ6; hsa:9685; Q14677; Q8NAF1; Q96E05"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"172.1"	"140.2"	"193.2"	"200.2"	"173.3"	"187.4"	"232.2"	"251.4"	"298.4"	"609.1"	"882.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N392"	"Rho GTPase-activating protein 18 OS=Homo sapiens OX=9606 GN=ARHGAP18 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"663"	"74.9"	"6.44"	"413.16"	"3.40"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity"	"Pf00620"	"93663"	"ENSG00000146376"	"ARHGAP18"	"E1P575; hsa:93663; Q58EZ3; Q6P679; Q6PJD7; Q8N392; Q96S64"	""	"RHOC GTPase cycle; RHOA GTPase cycle"	"2"	"0"	"16.0"	"11.9"	"14.9"	"16.0"	"13.0"	"13.6"	"37.6"	"31.5"	"57.9"	"337.8"	"345.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86YR5"	"G-protein-signaling modulator 1 OS=Homo sapiens OX=9606 GN=GPSM1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"675"	"74.5"	"6.54"	"395.60"	"3.40"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02188, Pf13424"	"26086"	"ENSG00000160360"	"GPSM1"	"A9Z1X4; B1B0W3; hsa:26086; Q86SR5; Q86YR5; Q969T1; Q9UFS8"	""	"G alpha (i) signalling events"	"1"	"0"	"22.2"	"15.4"	"22.9"	"26.1"	"18.2"	"18.5"	"31.9"	"25.9"	"32.2"	"77.5"	"114.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14139"	"Ubiquitin conjugation factor E4 A OS=Homo sapiens OX=9606 GN=UBE4A PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1066"	"122.5"	"5.24"	"389.37"	"3.39"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf04564, Pf10408"	"9354"	"ENSG00000110344"	"UBE4A"	"B0YJB6; hsa:9354; Q14139; Q2M1H0; Q6P5T4; Q7Z639"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"5.2"	"14.2"	"7.9"	"11.3"	"10.0"	"5.2"	"8.9"	"8.2"	"9.1"	"21.3"	"22.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43159"	"Ribosomal RNA-processing protein 8 OS=Homo sapiens OX=9606 GN=RRP8 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"456"	"50.7"	"9.42"	"344.67"	"3.39"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf05148"	"23378"	"ENSG00000132275"	"RRP8"	"hsa:23378; O43159; Q7KZ78; Q9BVM6"	""	"SIRT1 negatively regulates rRNA expression"	"1"	"0"	"8.2"	"7.0"	"7.2"	"5.8"	"8.3"	"5.3"	"21.5"	"18.1"	"35.5"	"80.9"	"74.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2G0"	"Protein EFR3 homolog B OS=Homo sapiens OX=9606 GN=EFR3B PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"817"	"92.4"	"6.70"	"307.28"	"3.39"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton"	""	""	"22979"	"ENSG00000084710"	"EFR3B"	"B7WPL8; hsa:22979; Q86XU6; Q9Y2G0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BV38"	"WD repeat-containing protein 18 OS=Homo sapiens OX=9606 GN=WDR18 PE=1 SV=2"	"0.001"	""	"3"	"1"	"2"	"1"	"432"	"47.4"	"6.70"	"257.93"	"3.38"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400, Pf14077"	"57418"	"ENSG00000065268"	"WDR18"	"hsa:57418; O60390; Q9BV38; Q9BWR2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"22.4"	"13.6"	"29.7"	"43.0"	"25.7"	"29.7"	"45.5"	"43.2"	"67.2"	"155.2"	"253.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UL18"	"Protein argonaute-1 OS=Homo sapiens OX=9606 GN=AGO1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"857"	"97.2"	"9.16"	"328.02"	"3.38"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02170, Pf02171, Pf08699, Pf16486, Pf16487, Pf16488"	"26523"	"ENSG00000092847"	"AGO1"	"hsa:26523; Q5TA57; Q6P4S0; Q9UL18"	"Modulators of TCR signaling and T cell activation"	"MAPK6/MAPK4 signaling; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Transcriptional regulation by small RNAs; Oxidative Stress Induced Senescence; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; TP53 Regulates Metabolic Genes; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Ca2+ pathway; Regulation of MECP2 expression and activity; MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Post-transcriptional silencing by small RNAs; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"22"	"0"	"22.7"	"23.1"	"33.0"	"37.6"	"37.0"	"22.7"	"32.9"	"46.1"	"49.3"	"126.2"	"178.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FZ2"	"Abasic site processing protein HMCES OS=Homo sapiens OX=9606 GN=HMCES PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"354"	"40.5"	"8.15"	"293.22"	"3.38"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02586"	"56941"	"ENSG00000183624"	"HMCES"	"A6NJR9; hsa:56941; Q96FZ2; Q96G34; Q9NRP3"	""	""	"0"	"0"	"12.2"	"23.1"	"13.7"	"24.5"	"18.8"	"12.8"	"36.6"	"45.2"	"61.1"	"159.5"	"187.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NBF2"	"NHL repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=NHLRC2 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"726"	"79.4"	"5.55"	""	"3.37"	""	"1"	""	"non-structural extracellular;cytosol;other cell component"	""	"Pf01436, Pf13905"	"374354"	"ENSG00000196865"	"NHLRC2"	"hsa:374354; Q8N1H1; Q8N5A6; Q8NBF2"	""	"Platelet degranulation"	"1"	"0"	"0.0"	"3.5"	"3.2"	"4.2"	"2.0"	"2.1"	"10.0"	"7.6"	"16.2"	"61.7"	"134.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IY81"	"pre-rRNA 2'-O-ribose RNA methyltransferase FTSJ3 OS=Homo sapiens OX=9606 GN=FTSJ3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"847"	"96.5"	"8.40"	"271.45"	"3.37"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf01728, Pf07780, Pf11861"	"117246"	"ENSG00000108592"	"FTSJ3"	"B2RCA5; D3DU22; hsa:117246; Q8IY81; Q8N3A3; Q8WXX1; Q9BWM4; Q9NXT6"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"42.9"	"33.2"	"54.8"	"67.1"	"49.0"	"47.7"	"76.4"	"81.8"	"95.9"	"304.9"	"682.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTF0"	"THUMP domain-containing protein 2 OS=Homo sapiens OX=9606 GN=THUMPD2 PE=2 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"503"	"56.4"	"7.81"	"334.86"	"3.36"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"nucleic acid binding activity;other molecular function"	"Pf01170, Pf02926"	"80745"	"ENSG00000138050"	"THUMPD2"	"A8K7I7; hsa:80745; Q53TT8; Q53TV0; Q9BTF0"	""	""	"0"	"0"	"2.7"	"4.0"	"5.2"	"9.0"	"2.2"	"1.4"	"9.6"	"9.7"	"11.0"	"37.6"	"35.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43920"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 5 OS=Homo sapiens OX=9606 GN=NDUFS5 PE=1 SV=3"	"0.000"	""	"21"	"2"	"2"	"2"	"106"	"12.5"	"9.14"	"282.08"	"3.36"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf10200"	"4725"	"ENSG00000168653"	"NDUFS5"	"hsa:4725; O43920"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"209.7"	"137.7"	"180.4"	"185.6"	"153.1"	"201.5"	"203.5"	"223.7"	"219.2"	"392.5"	"623.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRG9"	"Aladin OS=Homo sapiens OX=9606 GN=AAAS PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"546"	"59.5"	"7.50"	"402.31"	"3.36"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus"	""	"Pf00400"	"8086"	"ENSG00000094914"	"AAAS"	"hsa:8086; Q5JB47; Q9NRG9; Q9NWI6; Q9UG19"	""	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Viral Messenger RNA Synthesis; Transcriptional regulation by small RNAs; Transport of Mature mRNA derived from an Intron-Containing Transcript; HCMV Early Events; HCMV Late Events; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of DNA replication proteins; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; RHOA GTPase cycle"	"29"	"0"	"65.8"	"68.3"	"94.5"	"119.9"	"64.2"	"71.0"	"130.7"	"136.9"	"194.7"	"498.7"	"676.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NVS2"	"39S ribosomal protein S18a, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS18A PE=1 SV=1"	""	""	"8"	"1"	"1"	"1"	"196"	"22.2"	"10.33"	""	"3.35"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01084"	"55168"	"ENSG00000096080"	"MRPS18A"	"A6XND3; hsa:55168; Q5QPA4; Q9NVS2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18031"	"Tyrosine-protein phosphatase non-receptor type 1 OS=Homo sapiens OX=9606 GN=PTPN1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"435"	"49.9"	"6.27"	"291.43"	"3.35"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5770"	"ENSG00000196396"	"PTPN1"	"hsa:5770; P18031; Q5TGD8; Q9BQV9; Q9NQQ4"	"Leptin signaling pathway; Prolactin signaling pathway; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling"	"Insulin receptor recycling; Growth hormone receptor signaling; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; Negative regulation of MET activity; Integrin signaling; MECP2 regulates neuronal receptors and channels; PTK6 Down-Regulation"	"14"	"0"	"0.0"	"0.0"	"0.0"	"4.7"	"1.9"	"2.8"	"6.0"	"5.2"	"15.6"	"161.5"	"277.5"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q969S3"	"Zinc finger protein 622 OS=Homo sapiens OX=9606 GN=ZNF622 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"477"	"54.2"	"6.15"	""	"3.35"	""	"1"	"signal transduction;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf12171, Pf12756"	"90441"	"ENSG00000173545"	"ZNF622"	"hsa:90441; Q969S3"	""	""	"0"	"0"	"17.6"	"22.9"	"15.7"	"24.1"	"17.5"	"14.0"	"29.2"	"33.2"	"40.0"	"119.8"	"260.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NDI1"	"EH domain-binding protein 1 OS=Homo sapiens OX=9606 GN=EHBP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1231"	"139.9"	"5.35"	"268.65"	"3.34"	"1"	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle"	""	"Pf00307, Pf10358, Pf12130"	"23301"	"ENSG00000115504"	"EHBP1"	"hsa:23301; O94977; Q53TG7; Q53TV6; Q580X2; Q6NX72; Q6PIT3; Q6QNV2; Q8NDI1; Q9NWI9"	"Ciliary landscape"	""	"1"	"0"	"17.2"	"14.1"	"13.1"	"19.2"	"13.6"	"16.5"	"17.8"	"23.5"	"28.2"	"64.6"	"90.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q70E73"	"Ras-associated and pleckstrin homology domains-containing protein 1 OS=Homo sapiens OX=9606 GN=RAPH1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1250"	"135.2"	"8.85"	"380.33"	"3.34"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf00169, Pf00788"	"65059"	"ENSG00000173166"	"RAPH1"	"hsa:65059; Q70E73; Q96Q37; Q9C0I2"	""	""	"0"	"0"	"5.0"	"5.3"	"4.0"	"8.2"	"6.0"	"5.0"	"14.3"	"12.4"	"23.8"	"59.7"	"69.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UKU7"	"Isobutyryl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACAD8 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"415"	"45.0"	"7.85"	""	"3.34"	""	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"27034"	"ENSG00000151498"	"ACAD8"	"B7Z5W4; hsa:27034; Q6ZWP6; Q9BUS8; Q9UKU7"	""	"Branched-chain amino acid catabolism"	"1"	"0"	"244.5"	"200.4"	"272.8"	"328.6"	"216.2"	"248.7"	"289.2"	"282.6"	"334.8"	"640.3"	"1090.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14155"	"Rho guanine nucleotide exchange factor 7 OS=Homo sapiens OX=9606 GN=ARHGEF7 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"803"	"90.0"	"7.09"	"679.29"	"3.34"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00307, Pf00621, Pf07653, Pf16614, Pf16615"	"8874"	"ENSG00000102606"	"ARHGEF7"	"B1ALK6; B1ALK8; hsa:8874; Q14155; Q3LIA4; Q5W9H0; Q6P9G3; Q6PII2; Q86W63; Q8N3M1"	"Integrin-mediated cell adhesion; CAMKK2 pathway; Regulation of actin cytoskeleton"	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOJ GTPase cycle; RHOQ GTPase cycle; RHOV GTPase cycle; RHOU GTPase cycle; Ephrin signaling; EGFR downregulation"	"14"	"0"	"128.7"	"81.8"	"165.5"	"146.9"	"147.1"	"134.6"	"182.6"	"189.9"	"263.6"	"482.8"	"711.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82921"	"28S ribosomal protein S21, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS21 PE=1 SV=3"	"0.000"	""	"14"	"1"	"2"	"1"	"87"	"10.7"	"9.92"	"319.09"	"3.34"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01165"	"54460"	"ENSG00000266472"	"MRPS21"	"A0A075B746; hsa:54460; P82921; Q5TB11; Q9BST6"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"31.4"	"23.7"	"42.4"	"68.6"	"32.5"	"36.6"	"59.7"	"58.5"	"79.8"	"182.1"	"281.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P0DMN0"	"Sulfotransferase 1A4 OS=Homo sapiens OX=9606 GN=SULT1A4 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"295"	"34.2"	"6.01"	""	"3.34"	""	"1"	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00685"	"445329; 6818"	"ENSG00000213648"	"SULT1A4"	"B4DNV0; hsa:445329; hsa:6818; O95603; P0DMN0; P50224; Q1ET66; Q6ZWJ5"	"Sulfation biotransformation reaction; Metapathway biotransformation Phase I and II"	"Paracetamol ADME; Cytosolic sulfonation of small molecules"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y266"	"Nuclear migration protein nudC OS=Homo sapiens OX=9606 GN=NUDC PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"331"	"38.2"	"5.38"	"300.49"	"3.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf14050, Pf16273"	"10726"	"ENSG00000090273"	"NUDC"	"hsa:10726; Q5QP31; Q5QP35; Q9H0N2; Q9Y266; Q9Y2B6"	"Ciliary landscape; PAFAH1B1 copy number variation"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; RND2 GTPase cycle; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"9"	"0"	"36.8"	"39.0"	"52.4"	"71.6"	"38.9"	"50.4"	"58.6"	"71.4"	"87.3"	"209.0"	"573.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NHZ8"	"Anaphase-promoting complex subunit CDC26 OS=Homo sapiens OX=9606 GN=CDC26 PE=1 SV=1"	"0.000"	""	"14"	"1"	"2"	"1"	"85"	"9.8"	"6.81"	"336.78"	"3.33"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	""	"Pf10471"	"246184"	"ENSG00000176386"	"CDC26"	"hsa:246184; Q8NHZ8"	""	"Assembly of the pre-replicative complex; Separation of Sister Chromatids; Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"18"	"0"	"61.5"	"50.6"	"78.1"	"82.0"	"62.1"	"80.1"	"111.4"	"108.6"	"107.9"	"185.7"	"261.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPY8"	"Microtubule-associated protein RP/EB family member 3 OS=Homo sapiens OX=9606 GN=MAPRE3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"281"	"32.0"	"5.54"	"290.60"	"3.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf03271"	"22924"	"ENSG00000084764"	"MAPRE3"	"B7WPK5; hsa:22924; O00265; Q6FHB0; Q6FI15; Q9BZP7; Q9BZP8; Q9UPY8"	""	""	"0"	"0"	"14.2"	"18.7"	"17.8"	"23.6"	"18.4"	"20.9"	"37.0"	"42.4"	"69.3"	"109.6"	"148.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VWN6"	"Protein TASOR 2 OS=Homo sapiens OX=9606 GN=TASOR2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"2430"	"268.7"	"5.90"	"492.95"	"3.33"	"1"	"1"	"cell organization and biogenesis"	"cytosol;nucleus"	""	"Pf12480, Pf12509"	"54906"	"ENSG00000108021"	"TASOR2"	"hsa:54906; Q2YD91; Q5VWN5; Q5VWN6; Q6ZRQ8; Q8IVG4; Q9BUZ7; Q9H5J9; Q9H7A4; Q9H996; Q9NXA1"	""	""	"0"	"0"	"7.6"	"6.8"	"9.9"	"13.1"	"7.9"	"6.5"	"12.9"	"11.5"	"21.4"	"28.8"	"29.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00217"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS8 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"210"	"23.7"	"6.34"	"342.89"	"3.33"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf12838"	"4728"	"ENSG00000110717"	"NDUFS8"	"B2RB86; hsa:4728; O00217; Q0VDA8"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"41.3"	"23.9"	"54.0"	"77.1"	"46.1"	"44.4"	"92.5"	"81.1"	"162.0"	"584.5"	"778.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVK7"	"Spindle and kinetochore-associated protein 2 OS=Homo sapiens OX=9606 GN=SKA2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"121"	"14.2"	"7.33"	"382.50"	"3.33"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf16740"	"348235"	"ENSG00000182628"	"SKA2"	"A6NIL3; B3KPL3; E9PCB8; hsa:348235; Q8WVK7"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"6"	"0"	"76.1"	"54.9"	"64.9"	"91.8"	"73.0"	"75.1"	"118.7"	"132.4"	"172.2"	"334.3"	"388.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5T200"	"Zinc finger CCCH domain-containing protein 13 OS=Homo sapiens OX=9606 GN=ZC3H13 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1668"	"196.5"	"9.42"	"304.80"	"3.33"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00642"	"23091"	"ENSG00000123200"	"ZC3H13"	"A2A323; hsa:23091; O94936; Q5T1Z9; Q5T200; Q7Z7J3; Q8NDT6; Q9H0L6"	""	""	"0"	"0"	"57.7"	"49.6"	"65.4"	"79.8"	"50.1"	"59.0"	"86.1"	"88.7"	"114.0"	"237.5"	"321.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H410"	"Kinetochore-associated protein DSN1 homolog OS=Homo sapiens OX=9606 GN=DSN1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"356"	"40.0"	"7.05"	"296.14"	"3.32"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"non-structural extracellular;cytosol;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf08202"	"79980"	"ENSG00000149636"	"DSN1"	"B4DWT2; E1P5U9; hsa:79980; Q5JW55; Q5JW56; Q9H410; Q9H8P4"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Neutrophil degranulation"	"7"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT09"	"Protein canopy homolog 3 OS=Homo sapiens OX=9606 GN=CNPY3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"278"	"30.7"	"5.49"	"358.79"	"3.32"	"1"	"1"	"stress response"	"ER/Golgi"	"signal transduction activity or receptor binding"	"Pf11938"	"10695"	"ENSG00000137161"	"CNPY3"	"hsa:10695; O15412; Q0P6I2; Q8NF54; Q8WTU8; Q9BT09; Q9P0F2"	""	"Trafficking and processing of endosomal TLR"	"1"	"0"	"2.1"	"2.9"	"4.0"	"4.7"	"5.1"	"2.1"	"27.8"	"28.4"	"58.6"	"123.0"	"137.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZ29"	"Dedicator of cytokinesis protein 9 OS=Homo sapiens OX=9606 GN=DOCK9 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"2069"	"236.3"	"7.49"	"254.16"	"3.31"	"1"	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"enzyme regulator activity"	"Pf00169, Pf06920, Pf11878, Pf14429, Pf20421, Pf20422"	"23348"	"ENSG00000088387"	"DOCK9"	"B3KX25; E9PFM9; hsa:23348; Q5JUD4; Q5JUD6; Q5T2Q1; Q5TAN8; Q9BZ25; Q9BZ26; Q9BZ27; Q9BZ28; Q9BZ29; Q9UPU4"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; Factors involved in megakaryocyte development and platelet production"	"3"	"0"	"18.1"	"11.4"	"14.3"	"25.5"	"37.0"	"64.7"	"170.9"	"176.3"	"127.7"	"153.3"	"152.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYW5"	"E3 ubiquitin-protein ligase RNF168 OS=Homo sapiens OX=9606 GN=RNF168 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"571"	"65.0"	"7.96"	"389.05"	"3.31"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf14447"	"165918"	"ENSG00000163961"	"RNF168"	"hsa:165918; Q8IYW5; Q8NA67; Q96NS4"	"ATM signaling in development and disease ; 3q29 copy number variation syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; SUMOylation of DNA damage response and repair proteins; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"8"	"0"	"6.3"	"8.2"	"9.0"	"7.5"	"11.3"	"7.2"	"9.0"	"11.7"	"19.6"	"34.0"	"31.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GG9"	"DCN1-like protein 1 OS=Homo sapiens OX=9606 GN=DCUN1D1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"259"	"30.1"	"5.34"	"311.63"	"3.31"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03556, Pf14555"	"54165"	"ENSG00000043093"	"DCUN1D1"	"B2RB37; hsa:54165; Q7L3G9; Q8TEX7; Q96GG9; Q9H6M1; Q9HCT3"	""	"Neddylation"	"1"	"0"	"0.0"	"0.0"	"0.0"	"4.5"	"2.5"	"0.0"	"6.8"	"5.4"	"12.3"	"82.6"	"135.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y297"	"F-box/WD repeat-containing protein 1A OS=Homo sapiens OX=9606 GN=BTRC PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"605"	"68.8"	"7.96"	"300.28"	"3.30"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00400, Pf12125, Pf12937"	"8945"	"ENSG00000166167"	"BTRC"	"B5MD49; hsa:8945; Q5W141; Q5W142; Q9Y213; Q9Y297"	"TNF-alpha signaling pathway; Pleural mesothelioma"	"Downstream TCR signaling; Neddylation; FCERI mediated NF-kB activation; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; SCF-beta-TrCP mediated degradation of Emi1; Vpu mediated degradation of CD4; Degradation of beta-catenin by the destruction complex; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; NIK-->noncanonical NF-kB signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Regulation of PLK1 Activity at G2/M Transition; Deactivation of the beta-catenin transactivating complex; Circadian Clock; MAP3K8 (TPL2)-dependent MAPK1/3 activation; Prolactin receptor signaling"	"23"	"0"	"25.1"	"20.2"	"30.4"	"37.8"	"24.8"	"24.9"	"43.4"	"55.0"	"59.9"	"129.7"	"188.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWT3"	"Poly(A) polymerase gamma OS=Homo sapiens OX=9606 GN=PAPOLG PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"736"	"82.8"	"9.14"	"279.29"	"3.30"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01909, Pf04926, Pf04928"	"64895"	"ENSG00000115421"	"PAPOLG"	"B2RBH4; hsa:64895; Q59G05; Q969N1; Q9BWT3; Q9H8L2; Q9HAD0"	""	""	"0"	"0"	"13.9"	"11.1"	"20.3"	"20.4"	"15.2"	"17.0"	"39.0"	"38.5"	"70.6"	"114.9"	"131.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00303"	"Eukaryotic translation initiation factor 3 subunit F OS=Homo sapiens OX=9606 GN=EIF3F PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"357"	"37.5"	"5.45"	"288.53"	"3.29"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01398, Pf13012"	"8665"	"ENSG00000175390"	"EIF3F"	"A8K0S2; hsa:8665; O00303; Q6IB45; Q8N978"	"Translation factors; VEGFA-VEGFR2 signaling; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"9"	"0"	"22.3"	"16.4"	"21.2"	"29.5"	"17.9"	"11.9"	"30.0"	"31.3"	"46.2"	"85.5"	"333.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PII3"	"Coiled-coil domain-containing protein 174 OS=Homo sapiens OX=9606 GN=CCDC174 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"467"	"53.9"	"6.33"	"285.22"	"3.29"	"1"	"1"	""	"nucleus"	""	"Pf13300"	"51244"	"ENSG00000154781"	"CCDC174"	"hsa:51244; Q6PII3; Q96CS5"	""	""	"0"	"0"	"54.4"	"56.4"	"63.0"	"74.7"	"59.6"	"73.9"	"84.7"	"100.3"	"118.1"	"185.4"	"220.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92556"	"Engulfment and cell motility protein 1 OS=Homo sapiens OX=9606 GN=ELMO1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"727"	"83.8"	"6.28"	"357.15"	"3.29"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf04727, Pf11841, Pf16457"	"9844"	"ENSG00000155849"	"ELMO1"	"A4D1X6; hsa:9844; Q29R79; Q6ZTJ0; Q92556; Q96PB0; Q9H0I1"	"Chemokine signaling pathway; CCL18 signaling pathway"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; VEGFA-VEGFR2 Pathway; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Nef and signal transduction"	"7"	"0"	"9.0"	"10.0"	"18.2"	"19.2"	"27.4"	"38.2"	"87.9"	"90.9"	"75.1"	"82.0"	"99.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30048"	"Thioredoxin-dependent peroxide reductase, mitochondrial OS=Homo sapiens OX=9606 GN=PRDX3 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"256"	"27.7"	"7.78"	"298.20"	"3.29"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00578, Pf10417"	"10935"	"ENSG00000165672"	"PRDX3"	"B2R7Z0; D3DRC9; E9PH29; hsa:10935; P30048; P35690; Q0D2H1; Q13776; Q5T5V2; Q96HK4"	"Selenium micronutrient network"	"Detoxification of Reactive Oxygen Species"	"2"	"0"	"26.1"	"24.6"	"43.3"	"52.3"	"26.1"	"31.3"	"44.4"	"52.6"	"75.3"	"167.0"	"237.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H7D7"	"WD repeat-containing protein 26 OS=Homo sapiens OX=9606 GN=WDR26 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"661"	"72.1"	"6.16"	""	"3.29"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol;mitochondrion;nucleus;other cell component"	""	"Pf00400, Pf17814"	"80232"	"ENSG00000162923"	"WDR26"	"A0MNN3; hsa:80232; Q4G100; Q59EC4; Q5GLZ9; Q86UY4; Q9H3C2; Q9H7D7"	"Ciliary landscape"	""	"1"	"0"	"19.0"	"18.1"	"19.0"	"24.5"	"19.5"	"11.4"	"30.0"	"32.1"	"47.6"	"108.0"	"177.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60826"	"Coiled-coil domain-containing protein 22 OS=Homo sapiens OX=9606 GN=CCDC22 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"627"	"70.7"	"6.74"	"430.30"	"3.29"	"1"	"1"	"transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf05667"	"28952"	"ENSG00000101997"	"CCDC22"	"A8K7G1; hsa:28952; O60826"	""	"Neddylation"	"1"	"0"	"7.2"	"13.0"	"16.5"	"19.7"	"9.4"	"14.5"	"21.3"	"29.2"	"43.3"	"115.1"	"203.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L0Y3"	"tRNA methyltransferase 10 homolog C OS=Homo sapiens OX=9606 GN=TRMT10C PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"403"	"47.3"	"9.36"	"566.67"	"3.29"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01746"	"54931"	"ENSG00000174173"	"TRMT10C"	"hsa:54931; Q7L0Y3; Q9NRG5; Q9NX54; Q9Y596"	""	"tRNA processing in the mitochondrion; tRNA modification in the mitochondrion; rRNA processing in the mitochondrion"	"3"	"0"	"71.4"	"78.1"	"110.0"	"185.5"	"93.1"	"68.9"	"175.4"	"202.8"	"244.9"	"538.3"	"591.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXH7"	"Negative elongation factor C/D OS=Homo sapiens OX=9606 GN=NELFCD PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"590"	"66.2"	"5.10"	"386.75"	"3.28"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf04858"	"51497"	"ENSG00000101158"	"NELFCD"	"B4DE06; hsa:51497; Q8IXH7; Q9BYL2; Q9H405; Q9H888; Q9H8T3; Q9NVX5; Q9P029; Q9UGN1; Q9UGN2; Q9UGN3"	"Initiation of transcription and translation elongation at the HIV-1 LTR; 4p16.3 copy number variation"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"16"	"0"	"10.2"	"11.3"	"17.0"	"17.6"	"9.3"	"13.9"	"25.5"	"30.6"	"50.2"	"137.0"	"220.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13144"	"Translation initiation factor eIF-2B subunit epsilon OS=Homo sapiens OX=9606 GN=EIF2B5 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"721"	"80.3"	"5.08"	"387.56"	"3.28"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf02020"	"8893"	"ENSG00000145191"	"EIF2B5"	"hsa:8893; Q13144; Q541Z1; Q96D04"	"Translation factors; MicroRNAs in cardiomyocyte hypertrophy; DYRK1A involvement regarding cell proliferation in brain development; Primary ovarian insufficiency"	"Recycling of eIF2:GDP"	"5"	"0"	"11.9"	"14.1"	"15.9"	"19.0"	"14.2"	"13.6"	"21.2"	"24.9"	"31.4"	"101.5"	"182.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TED0"	"U3 small nucleolar RNA-associated protein 15 homolog OS=Homo sapiens OX=9606 GN=UTP15 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"518"	"58.4"	"9.11"	"293.22"	"3.28"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	""	"Pf00400, Pf09384"	"84135"	"ENSG00000164338"	"UTP15"	"B4DU75; B4DXK8; hsa:84135; Q6IA60; Q8TED0; Q96E08; Q9H9F8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16512"	"Serine/threonine-protein kinase N1 OS=Homo sapiens OX=9606 GN=PKN1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"942"	"103.9"	"6.37"	"364.13"	"3.27"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433, Pf02185"	"5585"	"ENSG00000123143"	"PKN1"	"A8K7W5; B2R9R4; B3KVN3; hsa:5585; Q15143; Q16512; Q504U4; Q8IUV5; Q9UD44"	"Apoptosis-related network due to altered Notch3 in ovarian cancer; PI3K-Akt signaling pathway; IL-18 signaling pathway; G13 signaling pathway"	"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; RAC1 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; RHOB GTPase cycle"	"10"	"0"	"53.1"	"39.5"	"56.7"	"61.6"	"47.8"	"46.0"	"76.0"	"79.7"	"116.5"	"442.2"	"626.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPA8"	"Transcription and mRNA export factor ENY2 OS=Homo sapiens OX=9606 GN=ENY2 PE=1 SV=1"	"0.001"	""	"7"	"1"	"2"	"1"	"101"	"11.5"	"9.33"	"243.97"	"3.27"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf10163"	"56943"	"ENSG00000120533"	"ENY2"	"B2RE52; G3V117; hsa:56943; Q9NPA8"	""	"HATs acetylate histones"	"1"	"0"	"61.6"	"68.1"	"86.6"	"110.6"	"78.5"	"63.8"	"120.0"	"141.8"	"149.3"	"386.8"	"496.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BTY7"	"Protein HGH1 homolog OS=Homo sapiens OX=9606 GN=HGH1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"390"	"42.1"	"4.81"	"315.08"	"3.27"	"1"	"1"	""	""	""	"Pf04063, Pf04064"	"51236"	"ENSG00000235173"	"HGH1"	"hsa:51236; P0CB43; Q9BTY7"	""	""	"0"	"0"	"4.9"	"3.9"	"5.5"	"7.6"	"6.8"	"5.3"	"6.6"	"9.9"	"14.2"	"43.5"	"42.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16637"	"Survival motor neuron protein OS=Homo sapiens OX=9606 GN=SMN1 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"294"	"31.8"	"6.55"	"521.16"	"3.26"	"2"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf06003"	"6606; 6607"	"ENSG00000172062; ENSG00000205571; ENSG00000273772; ENSG00000275349; ENSG00000277773"	"SMN1; SMN2"	"A8K0V4; hsa:6606; hsa:6607; Q13119; Q16637; Q549U5; Q96J51"	""	"SARS-CoV-2 modulates host translation machinery; snRNP Assembly"	"2"	"0"	"277.0"	"232.6"	"287.3"	"326.1"	"211.9"	"224.6"	"345.1"	"345.4"	"408.5"	"874.9"	"1303.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEQ6"	"Gem-associated protein 5 OS=Homo sapiens OX=9606 GN=GEMIN5 PE=1 SV=3"	"0.001"	""	"1"	"2"	"2"	"2"	"1508"	"168.5"	"6.62"	"251.56"	"3.26"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf00400, Pf12894"	"25929"	"ENSG00000082516"	"GEMIN5"	"hsa:25929; Q14CV0; Q8TEQ6; Q8WWV4; Q969W4; Q9H9K3; Q9UFI5"	""	"snRNP Assembly; SARS-CoV-2 modulates host translation machinery"	"2"	"0"	"8.6"	"9.7"	"12.3"	"13.1"	"13.2"	"7.1"	"23.0"	"19.6"	"38.8"	"102.5"	"201.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY5"	"Multivesicular body subunit 12A OS=Homo sapiens OX=9606 GN=MVB12A PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"273"	"28.8"	"8.91"	"395.37"	"3.26"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf10240"	"93343"	"ENSG00000141971"	"MVB12A"	"hsa:93343; Q96EY5; Q96I18"	"7q11.23 copy number variation syndrome"	"Budding and maturation of HIV virion; Membrane binding and targetting of GAG proteins; Endosomal Sorting Complex Required For Transport (ESCRT); Late endosomal microautophagy; HCMV Late Events"	"6"	"0"	"23.1"	"22.6"	"28.7"	"37.4"	"27.1"	"27.2"	"69.7"	"79.3"	"131.5"	"279.5"	"347.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32322"	"Pyrroline-5-carboxylate reductase 1, mitochondrial OS=Homo sapiens OX=9606 GN=PYCR1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"319"	"33.3"	"7.61"	"332.35"	"3.25"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"mitochondrion"	"other molecular function"	"Pf03807, Pf14748"	"5831"	"ENSG00000183010"	"PYCR1"	"A6NFM2; B4DMU0; hsa:5831; P32322; Q6FHI4; Q96DI6; Q9HBQ4"	"Amino acid metabolism; Metabolic reprogramming in colon cancer"	"Glutamate and glutamine metabolism"	"3"	"0"	"7.5"	"7.3"	"13.8"	"23.8"	"9.2"	"12.4"	"17.4"	"20.9"	"22.4"	"98.7"	"163.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NI08"	"Nuclear receptor coactivator 7 OS=Homo sapiens OX=9606 GN=NCOA7 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"942"	"106.1"	"5.59"	"586.71"	"3.25"	"2"	"1"	"stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf01476, Pf07534"	"135112"	"ENSG00000111912"	"NCOA7"	"B2RNS2; B7Z2C4; B9EH71; G8JL91; hsa:135112; Q3LID6; Q4G0V1; Q5TF95; Q6IPQ4; Q6NE83; Q86T89; Q8N1W4; Q8NI08"	"Aryl hydrocarbon receptor pathway"	""	"1"	"0"	"2.4"	"7.7"	"8.9"	"7.6"	"6.5"	"10.0"	"14.3"	"19.1"	"33.1"	"100.6"	"119.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23458"	"Tyrosine-protein kinase JAK1 OS=Homo sapiens OX=9606 GN=JAK1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1154"	"133.2"	"7.55"	"265.63"	"3.25"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;kinase activity;other molecular function"	"Pf07714, Pf17887, Pf18377, Pf18379"	"3716"	"ENSG00000162434"	"JAK1"	"hsa:3716; P23458; Q59GQ2; Q9UD26"	"IL-5 signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; IL-17 signaling pathway; Type III interferon signaling; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; IL-3 signaling pathway; TCA cycle nutrient use and invasiveness of ovarian cancer; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; PI3K-Akt signaling pathway; Immune response to tuberculosis; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; IL-10 anti-inflammatory signaling pathway ; Overview of interferons-mediated signaling pathway; Measles virus infection; Hepatitis B infection; EGFR tyrosine kinase inhibitor resistance; TGF-beta receptor signaling in skeletal dysplasias; Type I interferon induction and signaling during SARS-CoV-2 infection; Host-pathogen interaction of human coronaviruses - interferon induction; IL-2 signaling pathway; SARS coronavirus and innate immunity; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Th17 cell differentiation pathway; IL-26 signaling pathways; TGF-beta receptor signaling; Interferon type I signaling pathways; Type II interferon signaling"	"ISG15 antiviral mechanism; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Inactivation of CSF3 (G-CSF) signaling; Potential therapeutics for SARS; Interleukin receptor SHC signaling; RAF/MAP kinase cascade; Interleukin-7 signaling; Interleukin-10 signaling; Interleukin-4 and Interleukin-13 signaling; Interleukin-6 signaling; Regulation of IFNG signaling; Regulation of IFNA/IFNB signaling; MAPK3 (ERK1) activation; MAPK1 (ERK2) activation; IL-6-type cytokine receptor ligand interactions; Interleukin-20 family signaling; Interleukin-35 Signalling; Interleukin-12 signaling; Interleukin-27 signaling; IFNG signaling activates MAPKs; Interleukin-2 signaling; Other interleukin signaling; Interleukin-15 signaling; Interleukin-9 signaling; Interleukin-21 signaling"	"71"	"0"	"17.8"	"8.4"	"21.8"	"31.5"	"22.5"	"16.0"	"33.5"	"42.9"	"62.4"	"135.7"	"165.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96EY4"	"Translation machinery-associated protein 16 OS=Homo sapiens OX=9606 GN=TMA16 PE=1 SV=2"	"0.000"	""	"8"	"2"	"3"	"2"	"203"	"23.8"	"9.26"	"636.78"	"3.25"	"2"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf11176"	"55319"	"ENSG00000198498"	"TMA16"	"hsa:55319; Q0P6E4; Q0P6J1; Q96EY4; Q9NUR7"	""	""	"0"	"0"	"249.3"	"179.9"	"271.3"	"323.4"	"267.0"	"265.1"	"313.9"	"318.8"	"349.6"	"590.6"	"769.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAV7"	"GrpE protein homolog 1, mitochondrial OS=Homo sapiens OX=9606 GN=GRPEL1 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"217"	"24.3"	"8.12"	"335.16"	"3.24"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"other molecular function"	"Pf01025"	"80273"	"ENSG00000109519"	"GRPEL1"	"B2R783; hsa:80273; Q549M6; Q9HAV7"	""	"Mitochondrial protein import"	"1"	"0"	"23.1"	"17.7"	"32.6"	"45.4"	"23.5"	"27.1"	"35.5"	"37.6"	"51.3"	"100.6"	"125.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84022"	"Mothers against decapentaplegic homolog 3 OS=Homo sapiens OX=9606 GN=SMAD3 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"425"	"48.1"	"7.15"	"252.04"	"3.23"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf03165, Pf03166"	"4088"	"ENSG00000166949"	"SMAD3"	"A8K4B6; B7Z4Z5; B7Z6M9; B7Z9Q2; F5H383; hsa:4088; O09064; O09144; O14510; O35273; P84022; Q92940; Q93002; Q9GKR4"	"Androgen receptor signaling pathway; Cell cycle; AGE/RAGE pathway; Adipogenesis; Endoderm differentiation; Mesodermal commitment pathway; Extracellular vesicle-mediated signaling in recipient cells; Mesodermal commitment pathway; Ovarian infertility; Hepatitis C and hepatocellular carcinoma; Hypothesized pathways in pathogenesis of cardiovascular disease; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; Canonical and non-canonical TGF-B signaling; Chromosomal and microsatellite instability in colorectal cancer ; Epithelial to mesenchymal transition in colorectal cancer; Pancreatic adenocarcinoma pathway; Neovascularisation processes; Vitamin D in inflammatory diseases; Envelope proteins and their potential roles in EDMD physiopathology; Hippo signaling regulation pathways; Hepatitis B infection; TGF-beta receptor signaling in skeletal dysplasias; Overlap between signal transduction pathways contributing to LMNA laminopathies; Angiotensin II receptor type 1 pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Neuroinflammation and glutamatergic signaling; CCL18 signaling pathway; Progeria-associated lipodystrophy; GDNF signaling; Urotensin-II-mediated signaling pathway; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling; DNA damage response (only ATM dependent)"	"Ub-specific processing proteases; Formation of axial mesoderm; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Signaling by NODAL; FOXO-mediated transcription of cell cycle genes; Downregulation of TGF-beta receptor signaling; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Germ layer formation at gastrulation; Formation of definitive endoderm; SARS-CoV-1 targets host intracellular signalling and regulatory pathways; RUNX3 regulates BCL2L11 (BIM) transcription; Signaling by Activin; SMAD2/3 Phosphorylation Motif Mutants in Cancer; TGFBR1 KD Mutants in Cancer; Interleukin-37 signaling; RUNX3 regulates CDKN1A transcription; NOTCH4 Intracellular Domain Regulates Transcription; SMAD4 MH2 Domain Mutants in Cancer; SMAD2/3 MH2 Domain Mutants in Cancer"	"55"	"0"	"33.6"	"36.0"	"35.0"	"53.5"	"35.7"	"37.6"	"104.9"	"130.7"	"206.0"	"303.8"	"303.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14694"	"Ubiquitin carboxyl-terminal hydrolase 10 OS=Homo sapiens OX=9606 GN=USP10 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"798"	"87.1"	"5.31"	"358.99"	"3.23"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00443, Pf07145"	"9100"	"ENSG00000103194"	"USP10"	"B2RDJ8; B4DS84; hsa:9100; Q14694; Q9BWG7; Q9NSL7"	"VEGFA-VEGFR2 signaling"	"Ub-specific processing proteases; Termination of translesion DNA synthesis"	"3"	"0"	"55.7"	"42.1"	"80.7"	"102.7"	"71.2"	"54.7"	"100.5"	"90.8"	"136.7"	"303.8"	"457.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30041"	"Peroxiredoxin-6 OS=Homo sapiens OX=9606 GN=PRDX6 PE=1 SV=3"	"0.000"	""	"5"	"1"	"2"	"1"	"224"	"25.0"	"6.38"	"363.60"	"3.22"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00578, Pf10417"	"9588"	"ENSG00000117592"	"PRDX6"	"A8JZY7; hsa:9588; P30041; P32077; Q5TAH4; Q5ZEZ8"	"Nuclear receptors meta-pathway; NRF2 pathway; VEGFA-VEGFR2 signaling"	"Neutrophil degranulation; Detoxification of Reactive Oxygen Species"	"5"	"0"	"42.8"	"42.0"	"63.6"	"107.2"	"39.5"	"34.3"	"78.1"	"72.6"	"89.6"	"227.0"	"377.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P60228"	"Eukaryotic translation initiation factor 3 subunit E OS=Homo sapiens OX=9606 GN=EIF3E PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"445"	"52.2"	"6.04"	""	"3.22"	""	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf01399, Pf09440"	"3646"	"ENSG00000104408"	"EIF3E"	"hsa:3646; O43902; P60228; Q64058; Q64059; Q64252; Q6FG33; Q8WVK4"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"2.8"	"2.3"	"6.4"	"6.7"	"4.0"	"4.7"	"9.6"	"14.6"	"14.0"	"34.0"	"100.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N7R7"	"Cyclin-Y-like protein 1 OS=Homo sapiens OX=9606 GN=CCNYL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"359"	"40.7"	"6.07"	"370.68"	"3.22"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes"	"enzyme regulator activity;other molecular function"	"Pf00134"	"151195"	"ENSG00000163249"	"CCNYL1"	"hsa:151195; Q6NX60; Q8N7R7"	""	""	"0"	"0"	"139.6"	"139.5"	"145.5"	"181.2"	"118.9"	"119.1"	"257.6"	"245.9"	"386.5"	"1269.1"	"1895.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZU65"	"Ubinuclein-2 OS=Homo sapiens OX=9606 GN=UBN2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1347"	"146.0"	"9.19"	"279.28"	"3.22"	"1"	"1"	""	"nucleus"	""	"Pf08729, Pf14075"	"254048"	"ENSG00000157741"	"UBN2"	"A4D1S2; hsa:254048; Q2YDY4; Q6P1K0; Q6ZU65; Q86XN9; Q8N7D1"	""	""	"0"	"0"	"13.5"	"11.7"	"12.9"	"12.1"	"13.4"	"14.7"	"17.4"	"20.0"	"26.3"	"38.7"	"49.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00390"	"Glutathione reductase, mitochondrial OS=Homo sapiens OX=9606 GN=GSR PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"522"	"56.2"	"8.50"	""	"3.22"	""	"1"	"other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf00070, Pf02852"	"2936"	"ENSG00000104687"	"GSR"	"C8KIL8; C8KIL9; C8KIM0; D3DSV3; hsa:2936; P00390; Q7Z5C9; Q9NP63"	"Glutathione metabolism; Selenium micronutrient network; Trans-sulfuration, one-carbon metabolism and related pathways; Nuclear receptors meta-pathway; NRF2 pathway; Amino acid metabolism; Oxidative stress response; Vitamin D-sensitive calcium signaling in depression; Sulfation biotransformation reaction; Metapathway biotransformation Phase I and II"	""	"10"	"0"	"5.2"	"0.0"	"3.6"	"4.0"	"5.1"	"4.0"	"7.7"	"11.7"	"22.5"	"92.8"	"164.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P47914"	"60S ribosomal protein L29 OS=Homo sapiens OX=9606 GN=RPL29 PE=1 SV=2"	"0.000"	""	"9"	"1"	"2"	"1"	"159"	"17.7"	"11.66"	"389.00"	"3.22"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01779"	"6159"	"ENSG00000162244"	"RPL29"	"A8K0H3; B2R4M8; hsa:6159; P47914; Q6IPY3"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"19.8"	"29.0"	"45.4"	"30.2"	"25.3"	"21.9"	"33.4"	"28.7"	"37.1"	"62.5"	"101.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q92838"	"Ectodysplasin-A OS=Homo sapiens OX=9606 GN=EDA PE=1 SV=2"	""	""	"10"	"1"	"1"	"1"	"391"	"41.3"	"8.27"	""	"3.21"	""	"1"	"cell adhesion;cell-cell signaling;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding"	"Pf00229"	"1896"	"ENSG00000158813"	"EDA"	"A0AUZ2; A2A337; B7ZLU2; B7ZLU4; hsa:1896; O75910; Q5JS00; Q5JUM7; Q92838; Q9UP77; Q9Y6L0; Q9Y6L1; Q9Y6L2; Q9Y6L3; Q9Y6L4"	"Ectoderm differentiation; Ectoderm differentiation; EDA signaling in hair follicle development"	"TNFs bind their physiological receptors"	"4"	"0"	"11.3"	"9.3"	"14.4"	"20.8"	"15.4"	"17.5"	"139.5"	"170.1"	"307.3"	"862.1"	"1174.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CS2"	"HAUS augmin-like complex subunit 1 OS=Homo sapiens OX=9606 GN=HAUS1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"278"	"31.8"	"5.53"	"323.86"	"3.21"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	""	"115106"	"ENSG00000152240"	"HAUS1"	"B2RDM7; hsa:115106; Q8N837; Q96CS2"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"5.3"	"4.3"	"6.0"	"8.2"	"5.7"	"7.0"	"10.0"	"12.9"	"19.5"	"54.1"	"67.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55039"	"Developmentally-regulated GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=DRG2 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"364"	"40.7"	"8.88"	"247.47"	"3.21"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01926, Pf02824, Pf16897"	"1819"	"ENSG00000108591"	"DRG2"	"B2R8G5; hsa:1819; P55039; Q53Y50; Q9BWB2"	"Smith-Magenis and Potocki-Lupski syndrome copy number variation"	""	"1"	"0"	"3.6"	"6.4"	"7.6"	"14.4"	"4.2"	"5.3"	"12.2"	"11.8"	"12.9"	"76.5"	"114.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15678"	"Tyrosine-protein phosphatase non-receptor type 14 OS=Homo sapiens OX=9606 GN=PTPN14 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1187"	"135.2"	"8.31"	"295.82"	"3.21"	"1"	"1"	"protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102, Pf00373, Pf09379, Pf09380"	"5784"	"ENSG00000152104"	"PTPN14"	"hsa:5784; Q15678; Q5VSI0"	"VEGFA-VEGFR2 signaling"	"Interleukin-37 signaling"	"2"	"0"	"14.3"	"16.5"	"19.3"	"20.2"	"17.2"	"12.9"	"23.9"	"29.8"	"37.7"	"77.2"	"108.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14406"	"Cytochrome c oxidase subunit 7A2, mitochondrial OS=Homo sapiens OX=9606 GN=COX7A2 PE=1 SV=1"	"0.000"	""	"16"	"1"	"2"	"1"	"83"	"9.4"	"9.76"	"290.36"	"3.21"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02238"	"1347"	"ENSG00000112695"	"COX7A2"	"B2R5E1; hsa:1347; P14406; Q3MIH5; Q5TF59; Q6FGI2"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly"	""	"3"	"0"	"24.9"	"23.7"	"29.1"	"36.4"	"24.1"	"22.2"	"44.3"	"48.7"	"64.9"	"189.8"	"282.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N2Z9"	"Centromere protein S OS=Homo sapiens OX=9606 GN=CENPS PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"138"	"15.9"	"6.05"	"322.57"	"3.20"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf15630"	"100526739; 378708"	"ENSG00000175279"	"CENPS"	"hsa:100526739; hsa:378708; Q8N2Z9; Q8NFE5; Q8NFG5"	"DNA repair pathways, full network"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Fanconi Anemia Pathway; Deposition of new CENPA-containing nucleosomes at the centromere"	"9"	"0"	"18.8"	"11.1"	"17.6"	"14.3"	"21.7"	"11.9"	"21.2"	"24.3"	"29.8"	"76.7"	"97.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95163"	"Elongator complex protein 1 OS=Homo sapiens OX=9606 GN=ELP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1332"	"150.2"	"5.94"	"340.25"	"3.20"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04762"	"8518"	"ENSG00000070061"	"ELP1"	"hsa:8518; O95163; Q5JSV2; Q9H327; Q9UG87"	""	"HATs acetylate histones"	"1"	"0"	"13.6"	"8.2"	"14.7"	"16.9"	"12.5"	"17.1"	"29.2"	"28.6"	"47.2"	"189.8"	"407.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y248"	"DNA replication complex GINS protein PSF2 OS=Homo sapiens OX=9606 GN=GINS2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"2"	"1"	"185"	"21.4"	"5.44"	"283.21"	"3.20"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf05916"	"51659"	"ENSG00000131153"	"GINS2"	"D3DUM5; hsa:51659; Q6IAG9; Q9Y248"	""	"Unwinding of DNA"	"1"	"0"	"27.1"	"22.5"	"27.6"	"36.2"	"21.1"	"26.7"	"36.8"	"36.4"	"46.5"	"111.0"	"144.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42025"	"Beta-centractin OS=Homo sapiens OX=9606 GN=ACTR1B PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"376"	"42.3"	"6.40"	"304.55"	"3.20"	"1"	"1"	""	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00022"	"10120"	"ENSG00000115073"	"ACTR1B"	"D3DVH2; hsa:10120; P42025; Q53SK5; Q9BRB7"	""	"Neutrophil degranulation; MHC class II antigen presentation"	"2"	"0"	"22.6"	"13.8"	"23.4"	"27.8"	"17.5"	"20.1"	"32.0"	"38.0"	"45.3"	"119.3"	"215.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4B4"	"Helicase ARIP4 OS=Homo sapiens OX=9606 GN=RAD54L2 PE=1 SV=4"	"0.000"	""	"2"	"2"	"2"	"2"	"1467"	"162.7"	"6.09"	"261.43"	"3.19"	"1"	"1"	"cell organization and biogenesis"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271"	"23132"	"ENSG00000164080"	"RAD54L2"	"hsa:23132; Q8TB57; Q9BV54; Q9Y4B4"	"DYRK1A involvement regarding cell proliferation in brain development"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92541"	"RNA polymerase-associated protein RTF1 homolog OS=Homo sapiens OX=9606 GN=RTF1 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"710"	"80.3"	"8.15"	"400.20"	"3.19"	"1"	"1"	"cell-cell signaling;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf03126"	"23168"	"ENSG00000137815"	"RTF1"	"hsa:23168; Q92541; Q96BX6"	"Endoderm differentiation"	"Formation of RNA Pol II elongation complex ; RNA Polymerase II Pre-transcription Events; E3 ubiquitin ligases ubiquitinate target proteins"	"5"	"0"	"13.1"	"17.2"	"15.5"	"26.1"	"12.6"	"15.4"	"26.6"	"27.1"	"31.2"	"80.8"	"104.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXW5"	"Putative RNA polymerase II subunit B1 CTD phosphatase RPAP2 OS=Homo sapiens OX=9606 GN=RPAP2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"612"	"69.5"	"7.78"	"364.97"	"3.19"	"1"	"1"	"RNA metabolism OR transcription;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04181"	"79871"	"ENSG00000122484"	"RPAP2"	"C9JKB5; hsa:79871; Q49AS7; Q8IXW5; Q9H8Y2"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"8.7"	"5.9"	"11.2"	"12.5"	"7.2"	"4.5"	"13.3"	"9.5"	"13.7"	"16.2"	"27.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07602"	"Prosaposin OS=Homo sapiens OX=9606 GN=PSAP PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"524"	"58.1"	"5.17"	"362.56"	"3.19"	"1"	"1"	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02199, Pf03489, Pf05184"	"5660"	"ENSG00000197746"	"PSAP"	"hsa:5660; P07292; P07602; P15793; P78538; P78541; P78546; P78547; P78558; Q53Y86; Q6IBQ6; Q92739; Q92740; Q92741; Q92742"	"Degradation pathway of sphingolipids, including diseases"	"Glycosphingolipid metabolism; G alpha (i) signalling events; Neutrophil degranulation; Platelet degranulation ; Peptide ligand-binding receptors"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14737"	"Programmed cell death protein 5 OS=Homo sapiens OX=9606 GN=PDCD5 PE=1 SV=3"	"0.000"	""	"9"	"1"	"2"	"1"	"125"	"14.3"	"6.04"	"354.09"	"3.19"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01984"	"9141"	"ENSG00000105185"	"PDCD5"	"B4DE64; hsa:9141; O14737; Q53YC9; Q6IB70"	""	""	"0"	"0"	"33.5"	"33.1"	"47.7"	"73.6"	"49.1"	"32.5"	"87.2"	"107.5"	"183.7"	"275.8"	"629.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSG0"	"Protease-associated domain-containing protein 1 OS=Homo sapiens OX=9606 GN=PRADC1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"188"	"21.0"	"5.47"	"308.00"	"3.18"	"1"	"1"	""	"non-structural extracellular"	""	"Pf02225"	"84279"	"ENSG00000135617"	"PRADC1"	"hsa:84279; Q2Z1P2; Q9BSG0"	""	""	"0"	"0"	"36.5"	"17.4"	"33.0"	"45.9"	"24.0"	"34.2"	"40.7"	"35.8"	"41.8"	"67.1"	"82.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04114"	"Apolipoprotein B-100 OS=Homo sapiens OX=9606 GN=APOB PE=1 SV=2"	"0.000"	""	"0"	"1"	"2"	"1"	"4563"	"515.3"	"7.05"	"363.89"	"3.18"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;transporter activity;other molecular function"	"Pf01347, Pf06448, Pf09172, Pf12491"	"338"	"ENSG00000084674"	"APOB"	"hsa:338; O00502; P04114; P78479; P78480; P78481; Q13779; Q13785; Q13786; Q13787; Q13788; Q4ZG63; Q53QC8; Q7Z600; Q9UMN0"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Statin inhibition of cholesterol production; Male infertility; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins; Familial hyperlipidemia type 2; Cholesterol metabolism; Female steroid hormones in cardiomyocyte energy metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes; Enterocyte cholesterol metabolism"	"Cell surface interactions at the vascular wall; Scavenging by Class B Receptors; Regulation of TLR by endogenous ligand; Heme signaling; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Retinoid metabolism and transport; Cargo recognition for clathrin-mediated endocytosis; LDL clearance; Chylomicron clearance; Scavenging by Class A Receptors; Chylomicron assembly; Chylomicron remodeling; VLDL assembly; VLDL clearance; Scavenging by Class F Receptors; Scavenging by Class H Receptors; Platelet sensitization by LDL; LDL remodeling"	"31"	"0"	"0.0"	"0.0"	"0.0"	"0.0"	"2.8"	"0.0"	"5.8"	"6.1"	"12.0"	"59.2"	"91.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRP4"	"Proteasomal ATPase-associated factor 1 OS=Homo sapiens OX=9606 GN=PAAF1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"392"	"42.2"	"6.32"	"375.71"	"3.17"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf00400"	"80227"	"ENSG00000175575"	"PAAF1"	"A6NDR5; B4DPB0; B7ZAS9; hsa:80227; Q4G165; Q53HS9; Q7Z500; Q8TBU6; Q9BRP4; Q9HAB6"	""	""	"0"	"0"	"31.9"	"18.7"	"32.5"	"36.9"	"24.8"	"28.8"	"47.9"	"40.5"	"64.9"	"126.6"	"183.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75487"	"Glypican-4 OS=Homo sapiens OX=9606 GN=GPC4 PE=1 SV=4"	"0.000"	""	"3"	"2"	"3"	"2"	"556"	"62.4"	"6.68"	"609.68"	"3.17"	"2"	"1"	"cell adhesion;cell-cell signaling;cell organization and biogenesis;signal transduction;other biological processes"	"extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01153"	"2239"	"ENSG00000076716"	"GPC4"	"B2R6J7; B4E2C0; hsa:2239; O75487; Q6ZMA6; Q96L43; Q9NU08; Q9UJN1; Q9UPD9"	"Wnt signaling"	"A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport"	"11"	"0"	"145.2"	"144.8"	"143.3"	"187.6"	"150.4"	"130.5"	"190.9"	"205.3"	"241.0"	"523.1"	"760.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P11717"	"Cation-independent mannose-6-phosphate receptor OS=Homo sapiens OX=9606 GN=IGF2R PE=1 SV=3"	""	""	"0"	"1"	"1"	"1"	"2491"	"274.2"	"5.94"	""	"3.16"	""	"1"	"transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"kinase activity;other molecular function"	"Pf00040, Pf00878"	"3482"	"ENSG00000197081"	"IGF2R"	"hsa:3482; P11717; Q7Z7G9; Q96PT5"	"TROP2 regulatory signaling"	"Neutrophil degranulation; Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis; Retrograde transport at the Trans-Golgi-Network"	"6"	"0"	"2.4"	"0.0"	"2.2"	"4.5"	"3.1"	"0.0"	"5.5"	"10.7"	"14.3"	"74.3"	"134.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MG7"	"Non-structural maintenance of chromosomes element 3 homolog OS=Homo sapiens OX=9606 GN=NSMCE3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"304"	"34.3"	"9.28"	"382.63"	"3.16"	"1"	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01454"	"56160"	"ENSG00000185115; ENSG00000282130"	"NSMCE3"	"hsa:56160; Q8IW16; Q8TEI6; Q96MG7; Q9H214"	"15q11q13 copy number variation"	"SUMOylation of DNA damage response and repair proteins"	"2"	"0"	"21.7"	"22.5"	"21.9"	"27.9"	"20.0"	"25.8"	"38.8"	"34.1"	"40.6"	"85.4"	"102.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82932"	"28S ribosomal protein S6, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS6 PE=1 SV=3"	"0.000"	""	"10"	"1"	"2"	"1"	"125"	"14.2"	"9.26"	"272.25"	"3.16"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"nucleic acid binding activity;other molecular function"	"Pf01250"	"64968"	"ENSG00000243927"	"MRPS6"	"B2R573; hsa:64968; P82932; Q96Q64; Q9BSK8; Q9BW89"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"30.0"	"27.1"	"44.7"	"71.3"	"26.7"	"33.1"	"65.0"	"63.2"	"82.2"	"240.7"	"355.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q2VPK5"	"Cytoplasmic tRNA 2-thiolation protein 2 OS=Homo sapiens OX=9606 GN=CTU2 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"515"	"56.1"	"6.32"	"249.47"	"3.15"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10288"	"348180"	"ENSG00000174177"	"CTU2"	"B2RXK0; hsa:348180; Q0P511; Q2VPK5; Q66K78; Q6P4C8; Q86SV4"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43665"	"Regulator of G-protein signaling 10 OS=Homo sapiens OX=9606 GN=RGS10 PE=1 SV=3"	"0.000"	""	"6"	"1"	"2"	"1"	"181"	"21.2"	"7.49"	"331.63"	"3.15"	"1"	"1"	"cell-cell signaling;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00615"	"6001"	"ENSG00000148908"	"RGS10"	"A8K408; B1AMR8; hsa:6001; O43665; Q6IAZ6; Q96GN0"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Calcium regulation in cardiac cells"	"G alpha (i) signalling events"	"4"	"0"	"0.0"	"2.8"	"4.0"	"2.0"	"0.0"	"0.0"	"10.8"	"11.1"	"19.9"	"78.1"	"145.7"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TF72"	"Protein Shroom3 OS=Homo sapiens OX=9606 GN=SHROOM3 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1996"	"216.7"	"7.80"	"360.46"	"3.15"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf00595, Pf08687, Pf08688"	"57619"	"ENSG00000138771"	"SHROOM3"	"hsa:57619; Q5QTQ3; Q6ZRW3; Q8TF72; Q96IR9; Q9P247"	""	""	"0"	"0"	"8.6"	"10.0"	"12.3"	"13.9"	"6.2"	"9.9"	"13.8"	"14.8"	"18.4"	"29.5"	"29.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q68CZ1"	"Protein fantom OS=Homo sapiens OX=9606 GN=RPGRIP1L PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1315"	"151.1"	"5.35"	"271.76"	"3.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"signal transduction activity or receptor binding"	"Pf00168, Pf11618, Pf18111"	"23322"	"ENSG00000103494"	"RPGRIP1L"	"A0PJ88; hsa:23322; Q68CZ1; Q9Y2K8"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; NPHP1 deletion syndrome"	"Anchoring of the basal body to the plasma membrane; Hedgehog 'off' state"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z569"	"BRCA1-associated protein OS=Homo sapiens OX=9606 GN=BRAP PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"592"	"67.3"	"5.92"	"331.57"	"3.14"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02148, Pf07576, Pf13639"	"8315"	"ENSG00000089234"	"BRAP"	"B4DRM1; B9EGS8; hsa:8315; O43238; O75341; Q7Z569"	"Ras signaling"	"RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Negative regulation of MAPK pathway"	"6"	"0"	"37.5"	"39.4"	"35.3"	"49.1"	"39.4"	"41.7"	"69.7"	"64.2"	"93.3"	"142.0"	"140.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P12694"	"2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial OS=Homo sapiens OX=9606 GN=BCKDHA PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"445"	"50.4"	"8.27"	""	"3.14"	""	"1"	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00676"	"593"	"ENSG00000248098"	"BCKDHA"	"B4DP47; E7EW46; hsa:593; P12694; Q16034; Q16472"	"Lipid metabolism pathway"	"Glyoxylate metabolism and glycine degradation; Branched-chain amino acid catabolism"	"3"	"0"	"51.4"	"49.8"	"63.4"	"89.8"	"54.5"	"57.0"	"91.6"	"98.2"	"111.4"	"282.0"	"413.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16822"	"Phosphoenolpyruvate carboxykinase [GTP], mitochondrial OS=Homo sapiens OX=9606 GN=PCK2 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"640"	"70.7"	"7.62"	"412.12"	"3.14"	"1"	"1"	"other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00821, Pf17297"	"5106"	"ENSG00000100889; ENSG00000285241"	"PCK2"	"B4DW73; hsa:5106; O43253; Q16822; Q86U01; Q9BV62"	"Adipogenesis; Transcription factor regulation in adipogenesis; PPAR signaling pathway; PI3K-Akt signaling pathway; Krebs cycle disorders; DNA damage response (only ATM dependent)"	"Gluconeogenesis"	"7"	"0"	"34.7"	"23.2"	"48.8"	"62.6"	"30.9"	"33.8"	"56.1"	"55.2"	"74.3"	"266.8"	"468.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62910"	"60S ribosomal protein L32 OS=Homo sapiens OX=9606 GN=RPL32 PE=1 SV=2"	"0.000"	""	"7"	"1"	"2"	"1"	"135"	"15.9"	"11.33"	"287.35"	"3.14"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;other cell component"	"other molecular function"	"Pf01655"	"6161"	"ENSG00000144713"	"RPL32"	"B2R4Q3; hsa:6161; P02433; P62910"	"Cytoplasmic ribosomal proteins"	"SRP-dependent cotranslational protein targeting to membrane; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"26.5"	"34.0"	"42.4"	"47.5"	"36.6"	"33.1"	"94.5"	"112.5"	"178.2"	"398.7"	"662.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O76003"	"Glutaredoxin-3 OS=Homo sapiens OX=9606 GN=GLRX3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"335"	"37.4"	"5.39"	"365.17"	"3.13"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00085, Pf00462"	"10539"	"ENSG00000108010"	"GLRX3"	"B3KMP7; B3KMQ5; D3DRG2; hsa:10539; O76003; Q5JV01; Q96CE0; Q9P1B0; Q9P1B1"	""	"Iron uptake and transport"	"1"	"0"	"48.9"	"51.7"	"68.8"	"90.3"	"64.7"	"69.9"	"108.5"	"112.5"	"137.9"	"247.6"	"324.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IVD9"	"NudC domain-containing protein 3 OS=Homo sapiens OX=9606 GN=NUDCD3 PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"361"	"40.8"	"5.25"	""	"3.13"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf04969, Pf14050"	"23386"	"ENSG00000015676"	"NUDCD3"	"hsa:23386; Q8IVD9; Q9BTI3; Q9H7W9; Q9UPT4"	""	""	"0"	"0"	"12.2"	"8.2"	"12.4"	"11.1"	"12.4"	"7.8"	"14.7"	"15.2"	"22.5"	"44.7"	"39.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UL40"	"Zinc finger protein 346 OS=Homo sapiens OX=9606 GN=ZNF346 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"294"	"32.9"	"9.09"	""	"3.12"	""	"1"	""	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf12874"	"23567"	"ENSG00000113761"	"ZNF346"	"B7Z367; hsa:23567; Q68CV9; Q6ZMW1; Q9UL40"	"5q35 copy number variation"	""	"1"	"0"	"61.7"	"45.4"	"62.8"	"84.9"	"52.6"	"47.3"	"91.8"	"113.2"	"134.3"	"260.4"	"313.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13188"	"Serine/threonine-protein kinase 3 OS=Homo sapiens OX=9606 GN=STK3 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"2"	"491"	"56.3"	"5.24"	"552.62"	"3.11"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf11629"	"6788"	"ENSG00000104375"	"STK3"	"A8K722; B3KYA7; hsa:6788; Q13188; Q15445; Q15801; Q96FM6"	"MAPK signaling pathway; Transcription co-factors SKI and SKIL protein partners; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Hippo-YAP signaling; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Leukocyte-intrinsic Hippo pathway functions; Pleural mesothelioma"	"Signaling by Hippo"	"9"	"0"	"93.7"	"59.9"	"101.5"	"113.8"	"83.7"	"93.0"	"114.3"	"105.0"	"131.5"	"222.7"	"281.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00541"	"Pescadillo homolog OS=Homo sapiens OX=9606 GN=PES1 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"2"	"588"	"68.0"	"7.33"	"637.54"	"3.11"	"2"	"1"	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf06732, Pf16589"	"23481"	"ENSG00000100029"	"PES1"	"hsa:23481; O00541; Q6IC29"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"106.8"	"106.8"	"114.1"	"143.0"	"108.9"	"103.6"	"162.2"	"162.3"	"142.8"	"197.7"	"365.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60566"	"Mitotic checkpoint serine/threonine-protein kinase BUB1 beta OS=Homo sapiens OX=9606 GN=BUB1B PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"1050"	"119.5"	"5.27"	""	"3.10"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf08311"	"701"	"ENSG00000156970"	"BUB1B"	"B2R6U0; B4DL09; B4DLG3; hsa:701; O60501; O60566; O60627; O60758; O75389; Q59HH6; Q8WV50; Q96KM4"	"Regulation of sister chromatid separation at the metaphase-anaphase transition; 10q22q23 copy number variation"	"Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of mitotic proteins; APC-Cdc20 mediated degradation of Nek2A"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49914"	"5-formyltetrahydrofolate cyclo-ligase OS=Homo sapiens OX=9606 GN=MTHFS PE=1 SV=2"	"0.001"	""	"7"	"1"	"2"	"1"	"203"	"23.2"	"7.88"	"247.62"	"3.10"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf01812"	"10588"	"ENSG00000136371"	"MTHFS"	"H3BQ75; hsa:10588; P49914"	"Folate metabolism; One-carbon metabolism; Disorders of folate metabolism and transport"	"Metabolism of folate and pterines"	"4"	"0"	"46.2"	"32.7"	"59.5"	"63.8"	"48.9"	"48.0"	"81.6"	"101.1"	"125.9"	"285.8"	"384.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P34947"	"G protein-coupled receptor kinase 5 OS=Homo sapiens OX=9606 GN=GRK5 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"590"	"67.7"	"8.10"	""	"3.10"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00615"	"2869"	"ENSG00000198873"	"GRK5"	"D3DRD0; hsa:2869; P34947; Q5T059"	"Myometrial relaxation and contraction pathways; Chemokine signaling pathway; Comprehensive IL-17A signaling; Calcium regulation in cardiac cells"	"G alpha (q) signalling events; G alpha (s) signalling events"	"6"	"0"	"53.9"	"35.3"	"48.9"	"69.0"	"53.5"	"51.7"	"102.0"	"118.5"	"134.6"	"292.6"	"442.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969J3"	"BLOC-1-related complex subunit 5 OS=Homo sapiens OX=9606 GN=BORCS5 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"196"	"22.2"	"6.35"	"263.17"	"3.10"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf10158"	"118426"	"ENSG00000165714; ENSG00000280689"	"BORCS5"	"hsa:118426; Q969J3; Q96QS5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P09669"	"Cytochrome c oxidase subunit 6C OS=Homo sapiens OX=9606 GN=COX6C PE=1 SV=2"	"0.000"	""	"11"	"1"	"2"	"1"	"75"	"8.8"	"10.39"	"306.86"	"3.10"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	"Pf02937"	"1345"	"ENSG00000164919"	"COX6C"	"B2R4D7; hsa:1345; P09669"	"Electron transport chain: OXPHOS system in mitochondria; Ciliary landscape; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"8"	"0"	"96.0"	"120.8"	"110.9"	"145.4"	"80.5"	"104.0"	"196.6"	"223.6"	"306.4"	"1144.6"	"1837.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P14854"	"Cytochrome c oxidase subunit 6B1 OS=Homo sapiens OX=9606 GN=COX6B1 PE=1 SV=2"	"0.000"	""	"17"	"1"	"2"	"1"	"86"	"10.2"	"7.05"	"365.49"	"3.09"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf02297"	"1340"	"ENSG00000126267"	"COX6B1"	"B2R5C9; hsa:1340; P14854; Q6IBL4"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Mitochondrial complex IV assembly; 5q35 copy number variation"	"Respiratory electron transport; TP53 Regulates Metabolic Genes; Cytoprotection by HMOX1"	"7"	"0"	"36.6"	"39.7"	"48.0"	"62.2"	"63.1"	"36.4"	"72.3"	"68.9"	"79.8"	"162.1"	"211.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4X5"	"E3 ubiquitin-protein ligase ARIH1 OS=Homo sapiens OX=9606 GN=ARIH1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"557"	"64.1"	"5.08"	"285.75"	"3.09"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01485, Pf19422"	"25820"	"ENSG00000166233"	"ARIH1"	"B2R6U3; hsa:25820; O76026; Q9H3T6; Q9UEN0; Q9UP39; Q9Y4X5"	""	"ISG15 antiviral mechanism"	"1"	"0"	"15.3"	"9.3"	"20.6"	"19.8"	"15.9"	"17.2"	"32.5"	"36.6"	"51.8"	"114.5"	"111.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95983"	"Methyl-CpG-binding domain protein 3 OS=Homo sapiens OX=9606 GN=MBD3 PE=1 SV=1"	"0.000"	""	"10"	"2"	"4"	"2"	"291"	"32.8"	"5.34"	"1576.47"	"3.09"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"53615"	"ENSG00000071655"	"MBD3"	"A8K4B7; D6W5Z2; hsa:53615; O95983; Q6PIL9; Q6PJZ9; Q86XF4"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"HDACs deacetylate histones; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; Potential therapeutics for SARS; Regulation of PTEN gene transcription; RNA Polymerase I Transcription Initiation; Regulation of TP53 Activity through Acetylation"	"7"	"0"	"237.6"	"218.5"	"247.2"	"261.4"	"198.0"	"209.4"	"285.9"	"267.5"	"322.4"	"573.9"	"893.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P48729"	"Casein kinase I isoform alpha OS=Homo sapiens OX=9606 GN=CSNK1A1 PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"337"	"38.9"	"9.57"	""	"3.09"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1452"	"ENSG00000113712"	"CSNK1A1"	"D3DQG0; D3DQG1; hsa:1452; P48729; Q4JJA0; Q5U046; Q5U047; Q6FGA2; Q71TU5; Q96HD2; Q9UDK3"	"Alzheimer's disease and miRNA effects; T cell receptor and co-stimulatory signaling; Complement system; Wnt signaling pathway; Wnt/beta-catenin signaling pathway in leukemia; Regulation of Wnt / B-catenin signaling by small molecule compounds; Chromosomal and microsatellite instability in colorectal cancer ; Hedgehog signaling pathway; lncRNA in canonical Wnt signaling and colorectal cancer; Breast cancer pathway; Wnt signaling; ncRNAs involved in Wnt signaling in hepatocellular carcinoma; Influence of laminopathies on Wnt signaling; Overlap between signal transduction pathways contributing to LMNA laminopathies; Pleural mesothelioma; Alzheimer's disease; DYRK1A involvement regarding cell proliferation in brain development"	"Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Activation of SMO; Disassembly of the destruction complex and recruitment of AXIN to the membrane; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Maturation of nucleoprotein"	"32"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NZV5"	"Selenoprotein N OS=Homo sapiens OX=9606 GN=SELENON PE=1 SV=5"	""	""	"4"	"1"	"1"	"1"	"590"	"65.8"	"5.48"	""	"3.08"	""	"1"	"cell organization and biogenesis;stress response;developmental processes;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	""	"57190"	"ENSG00000162430"	"SELENON"	"A6NJG8; A8MQ64; hsa:57190; Q6PI70; Q969F6; Q9NUI6; Q9NZV5"	"Selenium micronutrient network"	""	"1"	"0"	"71.5"	"88.7"	"89.3"	"85.0"	"71.5"	"96.8"	"100.1"	"92.4"	"132.1"	"184.1"	"284.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75391"	"Sperm-associated antigen 7 OS=Homo sapiens OX=9606 GN=SPAG7 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"227"	"26.0"	"7.91"	"342.91"	"3.08"	"1"	"1"	""	"nucleus"	"nucleic acid binding activity"	"Pf01424"	"9552"	"ENSG00000091640"	"SPAG7"	"hsa:9552; O75391; Q96EU5"	""	""	"0"	"0"	"42.2"	"36.0"	"57.4"	"58.6"	"47.6"	"43.7"	"86.0"	"88.6"	"119.9"	"347.5"	"426.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB21"	"Pleckstrin homology domain-containing family A member 1 OS=Homo sapiens OX=9606 GN=PLEKHA1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"404"	"45.5"	"8.56"	"363.01"	"3.08"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59338"	"ENSG00000107679"	"PLEKHA1"	"B3KQ55; D3DRE2; hsa:59338; Q9BVK0; Q9HB21"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"27.5"	"16.3"	"29.6"	"35.5"	"30.4"	"45.0"	"102.3"	"111.3"	"156.1"	"188.2"	"195.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2I1"	"Nischarin OS=Homo sapiens OX=9606 GN=NISCH PE=1 SV=3"	"0.000"	""	"2"	"3"	"4"	"3"	"1504"	"166.5"	"5.14"	"834.51"	"3.08"	"3"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00787"	"11188"	"ENSG00000010322"	"NISCH"	"C9J245; hsa:11188; Q6PGP3; Q6PIB4; Q7L8M3; Q7Z2X6; Q9UES6; Q9UEU4; Q9UFW3; Q9Y2I1"	""	"RND3 GTPase cycle; RAC1 GTPase cycle; RND2 GTPase cycle"	"3"	"0"	"176.3"	"163.3"	"178.4"	"202.2"	"158.6"	"146.5"	"278.3"	"277.6"	"336.6"	"980.9"	"1287.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P087"	"Mitochondrial mRNA pseudouridine synthase RPUSD3 OS=Homo sapiens OX=9606 GN=RPUSD3 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"351"	"38.4"	"10.32"	"355.39"	"3.08"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf00849"	"285367"	"ENSG00000156990"	"RPUSD3"	"B4DS39; hsa:285367; Q6P087; Q6P6A9; Q8N1B2; Q8NAV3"	""	""	"0"	"0"	"13.4"	"8.3"	"12.7"	"21.5"	"8.8"	"14.3"	"23.6"	"20.7"	"26.0"	"48.2"	"86.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95801"	"Tetratricopeptide repeat protein 4 OS=Homo sapiens OX=9606 GN=TTC4 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"387"	"44.7"	"5.60"	"290.34"	"3.08"	"1"	"1"	"protein metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf18972"	"7268"	"ENSG00000243725"	"TTC4"	"hsa:7268; O95801; Q53Y95; Q5TA96; Q9H3I2"	""	""	"0"	"0"	"9.3"	"2.8"	"12.1"	"20.7"	"9.1"	"7.8"	"10.8"	"14.4"	"12.1"	"33.9"	"71.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q02388"	"Collagen alpha-1(VII) chain OS=Homo sapiens OX=9606 GN=COL7A1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"2944"	"295.0"	"6.27"	""	"3.08"	""	"1"	"cell adhesion;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;extracellular matrix;other membranes;ER/Golgi;other cell component"	"enzyme regulator activity;extracellular structural activity"	"Pf00014, Pf00041, Pf00092, Pf01391"	"1294"	"ENSG00000114270"	"COL7A1"	"hsa:1294; Q02388; Q14054; Q16507"	""	"Collagen degradation; Integrin cell surface interactions; Collagen chain trimerization; COPII-mediated vesicle transport; Cargo concentration in the ER; Laminin interactions; Anchoring fibril formation"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NW4"	"Ankyrin repeat domain-containing protein 27 OS=Homo sapiens OX=9606 GN=ANKRD27 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1050"	"116.9"	"6.87"	"361.99"	"3.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf02204, Pf12796"	"84079"	"ENSG00000105186"	"ANKRD27"	"hsa:84079; Q71MF5; Q86UC3; Q8ND80; Q96NW4; Q9H0I4"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	"38.9"	"35.0"	"34.3"	"40.8"	"33.4"	"37.2"	"62.9"	"73.6"	"90.1"	"191.4"	"232.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10644"	"cAMP-dependent protein kinase type I-alpha regulatory subunit OS=Homo sapiens OX=9606 GN=PRKAR1A PE=1 SV=1"	"0.001"	""	"5"	"1"	"2"	"1"	"381"	"43.0"	"5.35"	"242.28"	"3.07"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00027, Pf02197"	"5573"	"ENSG00000108946"	"PRKAR1A"	"hsa:5573; K7ER48; P10644; Q567S7"	"Mesodermal commitment pathway; Myometrial relaxation and contraction pathways; Mesodermal commitment pathway; G protein signaling pathways; Cannabinoid receptor signaling; Lipid metabolism pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Fragile X syndrome; Cardiomyocyte signaling pathways converging on Titin; Calcium regulation in cardiac cells; Sudden infant death syndrome (SIDS) susceptibility pathways"	"FCGR3A-mediated IL10 synthesis; GPER1 signaling; ADORA2B mediated anti-inflammatory cytokines production; ALK mutants bind TKIs; Signaling by ALK fusions and activated point mutants; Factors involved in megakaryocyte development and platelet production; Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Vasopressin regulates renal water homeostasis via Aquaporins; PKA activation; PKA activation in glucagon signalling; Hedgehog 'off' state; DARPP-32 events; CREB1 phosphorylation through the activation of Adenylate Cyclase"	"25"	"0"	"26.8"	"18.6"	"34.5"	"52.6"	"29.4"	"33.9"	"54.9"	"63.9"	"103.9"	"302.5"	"473.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WX93"	"Palladin OS=Homo sapiens OX=9606 GN=PALLD PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1383"	"150.5"	"7.09"	"326.86"	"3.06"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07679"	"23022"	"ENSG00000129116"	"PALLD"	"B3KTG2; B5MD56; B7ZMM5; hsa:23022; Q7L3E0; Q7Z3W0; Q86WE8; Q8N1M2; Q8WX93; Q9UGA0; Q9UQF5; Q9Y2J6; Q9Y3E9"	""	""	"0"	"0"	"17.2"	"13.0"	"20.2"	"21.2"	"16.9"	"19.7"	"29.3"	"31.4"	"63.3"	"165.6"	"230.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NP50"	"SIN3-HDAC complex-associated factor OS=Homo sapiens OX=9606 GN=SINHCAF PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"221"	"24.8"	"9.41"	""	"3.06"	""	"1"	"other biological processes"	"nucleus"	""	"Pf15396"	"58516"	"ENSG00000139146; ENSG00000276371"	"SINHCAF"	"D3DUV8; hsa:58516; Q9BSZ8; Q9NP50"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NS69"	"Mitochondrial import receptor subunit TOM22 homolog OS=Homo sapiens OX=9606 GN=TOMM22 PE=1 SV=3"	""	""	"18"	"1"	"1"	"1"	"142"	"15.5"	"4.34"	""	"3.06"	""	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf04281"	"56993"	"ENSG00000100216"	"TOMM22"	"hsa:56993; Q9NS69"	""	"PINK1-PRKN Mediated Mitophagy; Mitochondrial protein import"	"2"	"0"	"16.9"	"19.2"	"20.3"	"24.2"	"13.8"	"17.4"	"27.5"	"31.5"	"37.2"	"103.1"	"133.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y421"	"Protein FAM32A OS=Homo sapiens OX=9606 GN=FAM32A PE=1 SV=2"	"0.000"	""	"9"	"1"	"2"	"1"	"112"	"13.2"	"9.99"	"343.01"	"3.06"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus"	""	"Pf08555"	"26017"	"ENSG00000105058"	"FAM32A"	"hsa:26017; Q9BT02; Q9Y421"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"37.4"	"42.0"	"56.0"	"52.9"	"43.2"	"37.4"	"67.9"	"70.3"	"103.7"	"265.2"	"226.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UIF8"	"Bromodomain adjacent to zinc finger domain protein 2B OS=Homo sapiens OX=9606 GN=BAZ2B PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2168"	"240.3"	"6.54"	"274.68"	"3.06"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf01429, Pf02791, Pf15613"	"29994"	"ENSG00000123636"	"BAZ2B"	"D3DPA8; hsa:29994; Q96EA1; Q96SQ8; Q9P252; Q9UIF8; Q9Y4N8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53H47"	"Histone-lysine N-methyltransferase SETMAR OS=Homo sapiens OX=9606 GN=SETMAR PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"684"	"78.0"	"7.14"	"637.50"	"3.05"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00856, Pf01359, Pf05033, Pf17906"	"6419"	"ENSG00000170364"	"SETMAR"	"B4DY74; E7EN68; hsa:6419; Q13579; Q1G668; Q53H47; Q96F41"	"Histone modifications"	""	"1"	"0"	"39.4"	"30.3"	"39.4"	"66.9"	"36.3"	"40.3"	"96.3"	"101.7"	"175.9"	"559.9"	"759.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q53H12"	"Acylglycerol kinase, mitochondrial OS=Homo sapiens OX=9606 GN=AGK PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"422"	"47.1"	"8.09"	""	"3.05"	""	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"kinase activity;other molecular function"	"Pf00781, Pf19712"	"55750"	"ENSG00000006530; ENSG00000262327"	"AGK"	"hsa:55750; Q53H12; Q75KN1; Q96GC3; Q9NP48"	""	"Signaling by BRAF and RAF1 fusions; Glycerophospholipid biosynthesis"	"2"	"0"	"24.6"	"23.7"	"27.4"	"34.7"	"24.8"	"24.0"	"45.5"	"45.1"	"77.1"	"206.1"	"284.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95568"	"Histidine protein methyltransferase 1 homolog OS=Homo sapiens OX=9606 GN=METTL18 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"372"	"42.1"	"6.76"	"306.04"	"3.04"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13489"	"92342"	"ENSG00000171806"	"METTL18"	"B2R9T5; hsa:92342; O95568"	""	""	"0"	"0"	"7.1"	"11.1"	"15.2"	"12.5"	"8.3"	"7.3"	"16.9"	"15.7"	"27.2"	"81.1"	"94.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUT1"	"3-hydroxybutyrate dehydrogenase type 2 OS=Homo sapiens OX=9606 GN=BDH2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"245"	"26.7"	"7.65"	"323.23"	"3.04"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf13561"	"56898"	"ENSG00000164039"	"BDH2"	"A8K295; B4DUF6; hsa:56898; Q503A0; Q6IA46; Q6UWD3; Q9BUT1; Q9H8S8; Q9NRX8"	""	"Synthesis of Ketone Bodies"	"1"	"0"	"55.4"	"57.7"	"57.3"	"65.6"	"66.0"	"64.7"	"88.6"	"104.1"	"145.0"	"391.8"	"562.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3U8"	"60S ribosomal protein L36 OS=Homo sapiens OX=9606 GN=RPL36 PE=1 SV=3"	"0.000"	""	"15"	"2"	"3"	"2"	"105"	"12.2"	"11.59"	"611.50"	"3.04"	"2"	"1"	"protein metabolism;other metabolic processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf01158"	"25873"	"ENSG00000130255"	"RPL36"	"B2R4Y1; D6W634; hsa:25873; Q6FIG1; Q9UQF6; Q9Y3U8"	"Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Regulation of expression of SLITs and ROBOs; Selenocysteine synthesis; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"14"	"0"	"154.0"	"180.8"	"234.9"	"340.4"	"159.8"	"153.7"	"388.9"	"388.7"	"561.5"	"1642.8"	"2313.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6S0"	"3'-5' RNA helicase YTHDC2 OS=Homo sapiens OX=9606 GN=YTHDC2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1430"	"160.1"	"8.40"	"295.46"	"3.03"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf01424, Pf04146, Pf04408, Pf07717"	"64848"	"ENSG00000047188"	"YTHDC2"	"B2RP66; hsa:64848; Q9H6S0"	""	""	"0"	"0"	"15.3"	"16.5"	"17.9"	"22.5"	"21.1"	"19.6"	"22.4"	"24.3"	"33.9"	"82.9"	"128.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UN81"	"LINE-1 retrotransposable element ORF1 protein OS=Homo sapiens OX=9606 GN=L1RE1 PE=1 SV=1"	"0.001"	""	"5"	"1"	"2"	"1"	"338"	"40.0"	"9.51"	"243.05"	"3.03"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02994, Pf17489, Pf17490"	""	""	"L1RE1"	"Q15605; Q9UN81"	""	""	"0"	"0"	"48.6"	"28.1"	"501.7"	"42.9"	"49.8"	"31.3"	"75.3"	"55.3"	"61.6"	"158.6"	"297.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VSL9"	"Striatin-interacting protein 1 OS=Homo sapiens OX=9606 GN=STRIP1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"837"	"95.5"	"6.29"	"324.84"	"3.02"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf07923, Pf11882"	"85369"	"ENSG00000143093"	"STRIP1"	"hsa:85369; Q0V925; Q5VSL8; Q5VSL9; Q658K2; Q6ZV31; Q8N598; Q96SN2; Q9C0A2"	""	""	"0"	"0"	"33.0"	"29.1"	"41.9"	"47.7"	"35.7"	"39.2"	"60.3"	"60.9"	"80.0"	"213.7"	"349.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60220"	"Mitochondrial import inner membrane translocase subunit Tim8 A OS=Homo sapiens OX=9606 GN=TIMM8A PE=1 SV=1"	""	""	"11"	"1"	"1"	"1"	"97"	"11.0"	"5.16"	""	"3.02"	""	"1"	"cell organization and biogenesis;transport;developmental processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"1678"	"ENSG00000126953"	"TIMM8A"	"B2R5A6; hsa:1678; O60220; Q6IRW6"	""	"Mitochondrial protein import"	"1"	"0"	"25.9"	"22.1"	"24.0"	"38.1"	"18.7"	"20.9"	"44.3"	"54.4"	"66.1"	"247.0"	"455.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N335"	"Glycerol-3-phosphate dehydrogenase 1-like protein OS=Homo sapiens OX=9606 GN=GPD1L PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"351"	"38.4"	"7.02"	"336.12"	"3.02"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf01210, Pf07479"	"23171"	"ENSG00000152642"	"GPD1L"	"A8K9U3; hsa:23171; Q14702; Q8N335; Q9BRM5"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	"Synthesis of PA"	"2"	"0"	"88.1"	"83.7"	"108.8"	"125.3"	"68.9"	"80.7"	"145.7"	"147.5"	"198.9"	"534.0"	"932.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95721"	"Synaptosomal-associated protein 29 OS=Homo sapiens OX=9606 GN=SNAP29 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"258"	"29.0"	"5.81"	"323.18"	"3.01"	"1"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"9342"	"ENSG00000099940"	"SNAP29"	"hsa:9342; O95721"	"Ciliary landscape; 22q11.2 copy number variation syndrome"	"Neutrophil degranulation; Intra-Golgi traffic"	"4"	"0"	"37.6"	"32.0"	"36.2"	"41.7"	"33.1"	"32.9"	"49.8"	"58.5"	"70.0"	"106.8"	"152.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GD4"	"Aurora kinase B OS=Homo sapiens OX=9606 GN=AURKB PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"344"	"39.3"	"9.29"	"303.59"	"3.01"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"9212"	"ENSG00000178999"	"AURKB"	"B4DNM4; C7G533; C7G534; C7G535; D3DTR4; hsa:9212; J9JID1; O14630; O60446; O95083; Q96DV5; Q96GD4; Q9UQ46"	"Microtubule cytoskeleton regulation; ATM signaling in development and disease"	"Regulation of TP53 Activity through Phosphorylation; RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; SUMOylation of DNA replication proteins; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Regulation of MECP2 expression and activity"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35251"	"Replication factor C subunit 1 OS=Homo sapiens OX=9606 GN=RFC1 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1148"	"128.2"	"9.36"	"378.68"	"3.01"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00004, Pf00533, Pf08519"	"5981"	"ENSG00000035928"	"RFC1"	"A8K6E7; hsa:5981; P35251; Q5XKF5; Q6PKU0; Q86V41; Q86V46"	"miRNA regulation of DNA damage response; DNA replication; Male infertility; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair; DNA damage response"	"PCNA-Dependent Long Patch Base Excision Repair; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER"	"22"	"0"	"203.8"	"112.9"	"207.5"	"229.3"	"179.0"	"180.4"	"356.6"	"367.0"	"567.5"	"894.7"	"1036.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16342"	"Programmed cell death protein 2 OS=Homo sapiens OX=9606 GN=PDCD2 PE=1 SV=2"	"0.001"	""	"4"	"1"	"2"	"1"	"344"	"38.6"	"5.38"	"241.98"	"3.01"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01753, Pf04194"	"5134"	"ENSG00000071994"	"PDCD2"	"E9PCU7; F5GYS7; hsa:5134; Q16342; Q58HM9; Q58HN0; Q9UH12"	""	""	"0"	"0"	"15.4"	"16.8"	"11.2"	"17.6"	"17.5"	"14.9"	"34.4"	"32.5"	"47.9"	"186.4"	"279.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3D9"	"28S ribosomal protein S23, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS23 PE=1 SV=2"	"0.001"	""	"8"	"1"	"2"	"1"	"190"	"21.8"	"8.90"	"234.99"	"3.01"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus;nucleus"	"other molecular function"	"Pf10484"	"51649"	"ENSG00000181610"	"MRPS23"	"B2R6V3; hsa:51649; Q96Q24; Q9BWH8; Q9P053; Q9Y3D9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"44.6"	"41.9"	"44.4"	"51.2"	"48.6"	"41.7"	"69.5"	"69.8"	"115.4"	"203.6"	"253.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BZL1"	"Ubiquitin-like protein 5 OS=Homo sapiens OX=9606 GN=UBL5 PE=1 SV=1"	"0.000"	""	"22"	"3"	"4"	"3"	"73"	"8.5"	"8.44"	"842.41"	"3.00"	"3"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"other molecular function"	"Pf00240"	"59286"	"ENSG00000198258"	"UBL5"	"hsa:59286; Q2NL89; Q9BZL1"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"174.4"	"201.4"	"220.4"	"396.1"	"196.6"	"179.3"	"470.4"	"538.1"	"703.5"	"1884.0"	"3071.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01433"	"AMP deaminase 2 OS=Homo sapiens OX=9606 GN=AMPD2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"879"	"100.6"	"6.93"	"567.77"	"3.00"	"2"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf19326"	"271"	"ENSG00000116337"	"AMPD2"	"B4DK50; B4DZI5; E9PNG0; hsa:271; Q01433; Q14856; Q14857; Q16686; Q16687; Q16688; Q16729; Q5T693; Q5T695; Q96IA1; Q9UDX8; Q9UDX9; Q9UMU4"	""	"Purine salvage"	"1"	"0"	"24.0"	"16.6"	"32.1"	"47.8"	"27.4"	"18.2"	"60.1"	"52.6"	"70.8"	"167.8"	"307.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BH1"	"E3 ubiquitin-protein ligase RNF25 OS=Homo sapiens OX=9606 GN=RNF25 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"459"	"51.2"	"6.54"	"263.79"	"3.00"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf05773"	"64320"	"ENSG00000163481"	"RNF25"	"A8K0D6; hsa:64320; Q53HQ5; Q96BH1; Q9H874"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"9.1"	"12.9"	"8.2"	"7.5"	"7.2"	"9.1"	"12.8"	"9.5"	"22.2"	"39.6"	"33.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9T8"	"Protein KRI1 homolog OS=Homo sapiens OX=9606 GN=KRI1 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"2"	"703"	"82.5"	"5.14"	"796.26"	"3.00"	"2"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf05178, Pf12936"	"65095"	"ENSG00000129347"	"KRI1"	"hsa:65095; Q2M1R5; Q2M1R7; Q7L5J7; Q8N9T8; Q96G92; Q9BU50; Q9H6I1; Q9H978"	""	""	"0"	"0"	"346.4"	"310.5"	"391.8"	"402.1"	"322.2"	"365.1"	"432.1"	"433.2"	"513.3"	"754.9"	"1096.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6VY07"	"Phosphofurin acidic cluster sorting protein 1 OS=Homo sapiens OX=9606 GN=PACS1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"963"	"104.8"	"7.74"	"341.68"	"3.00"	"1"	"1"	"other biological processes"	"cytosol;ER/Golgi"	"other molecular function"	"Pf10254"	"55690"	"ENSG00000175115"	"PACS1"	"hsa:55690; Q6PJY6; Q6PKB6; Q6VY07; Q7Z590; Q7Z5W4; Q8N8K6; Q96MW0; Q9NW92; Q9ULP5"	""	"Nef mediated downregulation of MHC class I complex cell surface expression"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4F1"	"FERM, ARHGEF and pleckstrin domain-containing protein 1 OS=Homo sapiens OX=9606 GN=FARP1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1045"	"118.6"	"8.15"	"603.04"	"2.99"	"2"	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00169, Pf00373, Pf00621, Pf08736, Pf09379, Pf09380"	"10160"	"ENSG00000152767"	"FARP1"	"hsa:10160; Q5JVI9; Q6IQ29; Q9Y4F1"	""	"RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOF GTPase cycle"	"4"	"0"	"302.6"	"180.1"	"313.5"	"284.4"	"242.9"	"266.2"	"314.9"	"296.6"	"347.1"	"522.7"	"685.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WTS6"	"Histone-lysine N-methyltransferase SETD7 OS=Homo sapiens OX=9606 GN=SETD7 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"366"	"40.7"	"4.63"	"290.04"	"2.99"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00856, Pf02493"	"80854"	"ENSG00000145391"	"SETD7"	"B5WWL3; hsa:80854; Q0VAH3; Q4W5A9; Q8WTS6; Q9C0E6"	"Histone modifications"	"PKMTs methylate histone lysines"	"2"	"0"	"42.5"	"43.8"	"39.1"	"45.6"	"49.6"	"56.8"	"96.9"	"102.4"	"123.3"	"262.4"	"285.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NKF1"	"SAC3 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=SAC3D1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"404"	"43.5"	"8.69"	"343.31"	"2.99"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;nucleus;other cell component"	""	"Pf03399"	""	""	"SAC3D1"	"A6NKF1; A8MX08; Q99773"	""	""	"0"	"0"	"43.9"	"37.9"	"29.4"	"60.5"	"19.5"	"18.5"	"59.0"	"63.7"	"85.5"	"223.6"	"333.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q17RY0"	"Cytoplasmic polyadenylation element-binding protein 4 OS=Homo sapiens OX=9606 GN=CPEB4 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"729"	"80.1"	"7.18"	"390.11"	"2.97"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"ER/Golgi;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf16366, Pf16367"	"80315"	"ENSG00000113742"	"CPEB4"	"B7ZLQ7; hsa:80315; Q17RY0; Q7Z310; Q8N405; Q9C0J0"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	""	"2"	"0"	"29.6"	"21.5"	"33.6"	"38.8"	"22.8"	"26.1"	"43.8"	"50.4"	"77.9"	"270.1"	"372.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBZ3"	"WD repeat-containing protein 20 OS=Homo sapiens OX=9606 GN=WDR20 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"569"	"62.9"	"8.00"	"314.27"	"2.97"	"1"	"1"	""	"nucleus"	""	"Pf00400"	"91833"	"ENSG00000140153"	"WDR20"	"B4DN18; E7EUY8; F8W9S4; G3V2F8; G3V5R0; H0YJJ1; hsa:91833; Q86TU2; Q8NCN7; Q8TBZ3; Q8WXX2; Q9UF86"	""	"Ub-specific processing proteases"	"1"	"0"	"19.0"	"13.6"	"20.3"	"22.2"	"18.8"	"16.7"	"25.9"	"27.7"	"41.6"	"95.7"	"158.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25788"	"Proteasome subunit alpha type-3 OS=Homo sapiens OX=9606 GN=PSMA3 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"255"	"28.4"	"5.33"	"375.69"	"2.97"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00227, Pf10584"	"5684"	"ENSG00000100567"	"PSMA3"	"B2RCK6; hsa:5684; P25788; Q86U83; Q8N1D8; Q9BS70"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Alzheimer's disease"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2; Cross-presentation of soluble exogenous antigens (endosomes); Regulation of ornithine decarboxylase (ODC); Somitogenesis"	"62"	"0"	"115.2"	"70.1"	"166.2"	"168.4"	"123.4"	"120.5"	"160.8"	"138.9"	"157.9"	"224.3"	"400.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82930"	"28S ribosomal protein S34, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS34 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"218"	"25.6"	"9.98"	"315.97"	"2.97"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf16053"	"65993"	"ENSG00000074071"	"MRPS34"	"hsa:65993; P82930; Q9BVI7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"112.7"	"121.0"	"148.5"	"159.6"	"118.4"	"107.6"	"171.4"	"173.5"	"213.9"	"381.9"	"558.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z628"	"Neuroepithelial cell-transforming gene 1 protein OS=Homo sapiens OX=9606 GN=NET1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"596"	"67.7"	"9.23"	"327.30"	"2.96"	"1"	"1"	"stress response;signal transduction;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity"	"Pf00169, Pf00621"	"10276"	"ENSG00000173848"	"NET1"	"hsa:10276; Q12773; Q7Z628; Q96D82; Q99903; Q9UEN6"	"Apoptosis-related network due to altered Notch3 in ovarian cancer"	"RHOA GTPase cycle; RHOB GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events"	"5"	"0"	"9.3"	"9.6"	"14.2"	"13.7"	"8.4"	"10.4"	"17.2"	"18.9"	"20.3"	"31.4"	"44.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P33981"	"Dual specificity protein kinase TTK OS=Homo sapiens OX=9606 GN=TTK PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"857"	"97.0"	"8.16"	"426.39"	"2.96"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"7272"	"ENSG00000112742"	"TTK"	"A8K8U5; B2RDW2; E1P543; hsa:7272; P33981; Q15272; Q5TCS0; Q9BW51; Q9NTM0"	"Cell cycle; Retinoblastoma gene in cancer"	""	"2"	"0"	"23.7"	"13.4"	"25.1"	"38.4"	"26.3"	"28.7"	"40.8"	"37.5"	"65.5"	"197.4"	"350.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P07686"	"Beta-hexosaminidase subunit beta OS=Homo sapiens OX=9606 GN=HEXB PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"556"	"63.1"	"6.76"	"312.18"	"2.95"	"1"	"1"	"other metabolic processes"	"other cytoplasmic organelle"	"other molecular function"	"Pf00728, Pf14845"	"3074"	""	"HEXB"	"A0A024RAJ6; hsa:3074"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19623"	"Spermidine synthase OS=Homo sapiens OX=9606 GN=SRM PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"302"	"33.8"	"5.49"	"321.39"	"2.95"	"1"	"1"	"other metabolic processes;other biological processes"	"cytosol"	"other molecular function"	"Pf01564, Pf17284"	"6723"	"ENSG00000116649"	"SRM"	"B1AKP9; hsa:6723; P19623; Q15511"	"Methionine de novo and salvage pathway; Amino acid metabolism"	"Metabolism of polyamines"	"3"	"0"	"119.0"	"101.1"	"110.7"	"161.9"	"85.3"	"102.6"	"138.5"	"142.4"	"174.8"	"371.7"	"470.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95490"	"Adhesion G protein-coupled receptor L2 OS=Homo sapiens OX=9606 GN=ADGRL2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1459"	"163.2"	"6.43"	"401.20"	"2.95"	"1"	"1"	"developmental processes;signal transduction"	"other membranes;other cell component"	"other molecular function"	"Pf00002, Pf01825, Pf02140, Pf02191, Pf02354, Pf02793, Pf16489"	"23266"	"ENSG00000117114"	"ADGRL2"	"A5XEI2; B1ALT8; B1ALT9; B1ALU0; B1ALU2; B1ALU4; B1ALU5; B1ALU6; hsa:23266; O94882; O95490; Q5VX76; Q9UKY5; Q9UKY6"	"GPCRs, other; GPCRs, class B secretin-like"	""	"2"	"0"	"4.1"	"4.3"	"2.2"	"2.5"	"5.7"	"5.9"	"5.8"	"7.7"	"18.5"	"88.3"	"118.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O96008"	"Mitochondrial import receptor subunit TOM40 homolog OS=Homo sapiens OX=9606 GN=TOMM40 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"361"	"37.9"	"7.25"	"268.37"	"2.95"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;mitochondrion;other cell component"	"transporter activity"	"Pf01459"	"10452"	"ENSG00000130204"	"TOMM40"	"A0A024R0P9; hsa:10452; O96008; Q86VW4; Q8WY09; Q8WY10; Q8WY11; Q9BR95"	"IL-18 signaling pathway"	"Mitochondrial protein import; PINK1-PRKN Mediated Mitophagy"	"3"	"0"	"0.0"	"5.1"	"5.3"	"5.2"	"2.1"	"2.5"	"9.8"	"7.5"	"11.3"	"30.4"	"47.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N1G2"	"Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 OS=Homo sapiens OX=9606 GN=CMTR1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"835"	"95.3"	"7.05"	""	"2.95"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01585, Pf01728"	"23070"	"ENSG00000137200"	"CMTR1"	"A8K949; hsa:23070; Q14670; Q8N1G2; Q96FJ9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DT7"	"Zinc finger and BTB domain-containing protein 10 OS=Homo sapiens OX=9606 GN=ZBTB10 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"871"	"94.8"	"5.16"	"293.31"	"2.95"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00651, Pf13909"	"65986"	"ENSG00000205189"	"ZBTB10"	"A4FVD0; hsa:65986; Q86W96; Q8IXI9; Q96DT7; Q96MH9"	""	""	"0"	"0"	"33.7"	"24.3"	"35.0"	"36.7"	"26.6"	"34.6"	"51.9"	"51.9"	"76.1"	"130.8"	"182.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95299"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 10, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFA10 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"355"	"40.7"	"8.48"	"542.67"	"2.94"	"2"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;other cell component"	"transporter activity"	"Pf01712"	"4705"	"ENSG00000130414"	"NDUFA10"	"hsa:4705; O95299; Q8WXC9"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; 2q37 copy number variation syndrome; Oxidative phosphorylation"	"Complex I biogenesis"	"6"	"0"	"49.9"	"46.1"	"53.3"	"65.2"	"48.5"	"30.2"	"75.7"	"80.8"	"97.7"	"179.6"	"249.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51665"	"26S proteasome non-ATPase regulatory subunit 7 OS=Homo sapiens OX=9606 GN=PSMD7 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"324"	"37.0"	"6.77"	"261.70"	"2.94"	"1"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;cytosol;nucleus;other cell component"	"other molecular function"	"Pf01398, Pf13012"	"5713"	"ENSG00000103035"	"PSMD7"	"D3DWS9; hsa:5713; P51665; Q6PKI2; Q96E97"	"Proteasome degradation; Alzheimer's disease and miRNA effects; Parkin-ubiquitin proteasomal system pathway; Ciliary landscape; Alzheimer's disease"	"Neutrophil degranulation; Regulation of expression of SLITs and ROBOs; Orc1 removal from chromatin; Assembly of the pre-replicative complex; Separation of Sister Chromatids; FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"65"	"0"	"11.7"	"10.6"	"15.6"	"24.7"	"14.5"	"15.0"	"21.7"	"26.2"	"28.6"	"89.7"	"134.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51452"	"Dual specificity protein phosphatase 3 OS=Homo sapiens OX=9606 GN=DUSP3 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"185"	"20.5"	"7.80"	"304.25"	"2.94"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;cytosol;nucleus;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00782"	"1845"	"ENSG00000108861"	"DUSP3"	"D3DX45; hsa:1845; P51452; Q5U0J1; Q8IYJ9"	"MAPK signaling pathway; Fragile X syndrome"	"ERKs are inactivated"	"3"	"0"	"28.9"	"21.6"	"29.8"	"42.6"	"27.8"	"38.7"	"37.9"	"45.3"	"77.4"	"194.2"	"328.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUL8"	"Programmed cell death protein 10 OS=Homo sapiens OX=9606 GN=PDCD10 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"212"	"24.7"	"8.19"	"318.07"	"2.93"	"1"	"1"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf06840"	"11235"	"ENSG00000114209"	"PDCD10"	"A8K515; D3DNN5; hsa:11235; O14811; Q9BUL8"	""	""	"0"	"0"	"99.0"	"83.2"	"99.8"	"134.4"	"85.9"	"88.0"	"134.5"	"156.7"	"155.7"	"475.8"	"768.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82673"	"28S ribosomal protein S35, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS35 PE=1 SV=1"	"0.000"	""	"10"	"4"	"5"	"4"	"323"	"36.8"	"8.24"	"1143.31"	"2.93"	"4"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf10213"	"60488"	"ENSG00000061794"	"MRPS35"	"hsa:60488; P82673; Q32LZ1; Q6P4C6; Q7L1M6; Q8NBP4; Q96AI0; Q9H044; Q9HC14; Q9P1R5"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"445.2"	"349.8"	"433.8"	"435.7"	"371.9"	"433.8"	"541.5"	"525.7"	"668.4"	"1104.8"	"1668.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXE8"	"Pre-mRNA-splicing factor CWC25 homolog OS=Homo sapiens OX=9606 GN=CWC25 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"425"	"49.6"	"10.18"	"402.97"	"2.93"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10197, Pf12542"	"54883"	"ENSG00000273559; ENSG00000276761"	"CWC25"	"A0JLM3; hsa:54883; Q68DK5; Q9NXE8"	"17q12 copy number variation syndrome"	"mRNA Splicing - Major Pathway"	"2"	"0"	"53.7"	"44.8"	"53.7"	"65.2"	"51.2"	"42.5"	"81.1"	"90.5"	"109.5"	"149.7"	"154.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60870"	"DNA/RNA-binding protein KIN17 OS=Homo sapiens OX=9606 GN=KIN PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"393"	"45.3"	"8.95"	"398.58"	"2.93"	"1"	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10357, Pf18131"	"22944"	"ENSG00000151657"	"KIN"	"B4DX32; hsa:22944; O60870"	""	"Protein methylation"	"1"	"0"	"278.6"	"189.6"	"260.8"	"283.8"	"238.1"	"249.3"	"307.7"	"314.2"	"365.4"	"595.3"	"737.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDR0"	"TRAF3-interacting protein 1 OS=Homo sapiens OX=9606 GN=TRAF3IP1 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"691"	"78.6"	"7.93"	"593.41"	"2.92"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf10243, Pf17749"	"26146"	"ENSG00000204104"	"TRAF3IP1"	"hsa:26146; Q6PCT1; Q7L8N9; Q8TDR0; Q9NRD6; Q9Y4Q1"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; 2q37 copy number variation syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport"	"6"	"0"	"52.3"	"38.1"	"67.7"	"68.6"	"60.2"	"50.7"	"76.3"	"85.4"	"100.4"	"204.8"	"269.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95182"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 7 OS=Homo sapiens OX=9606 GN=NDUFA7 PE=1 SV=3"	"0.000"	""	"8"	"1"	"2"	"1"	"113"	"12.5"	"10.18"	"310.39"	"2.92"	"1"	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;mitochondrion;translational apparatus"	"transporter activity;other molecular function"	"Pf07347"	"4701"	"ENSG00000267855"	"NDUFA7"	"hsa:4701; O95182"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"41.7"	"57.9"	"42.0"	"51.4"	"48.7"	"39.7"	"68.6"	"101.7"	"135.4"	"323.1"	"348.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08240"	"Signal recognition particle receptor subunit alpha OS=Homo sapiens OX=9606 GN=SRPRA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"638"	"69.8"	"8.95"	"321.04"	"2.91"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00448, Pf02881, Pf04086"	"6734"	"ENSG00000182934"	"SRPRA"	"A6NIB3; B2R5Z8; B4E0H3; E9PJS4; hsa:6734; P08240; Q9BVJ4"	""	"SRP-dependent cotranslational protein targeting to membrane; XBP1(S) activates chaperone genes"	"2"	"0"	"5.5"	"7.2"	"7.4"	"7.5"	"8.1"	"7.5"	"13.8"	"16.9"	"24.0"	"56.5"	"66.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H1E3"	"Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 OS=Homo sapiens OX=9606 GN=NUCKS1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"243"	"27.3"	"5.08"	"329.18"	"2.90"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"64710"	"ENSG00000069275"	"NUCKS1"	"hsa:64710; Q54AC0; Q5PXE7; Q9H1D6; Q9H1E3; Q9H723"	""	""	"0"	"0"	"96.2"	"101.2"	"106.8"	"133.2"	"93.3"	"73.0"	"146.0"	"156.1"	"212.7"	"483.3"	"651.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75446"	"Histone deacetylase complex subunit SAP30 OS=Homo sapiens OX=9606 GN=SAP30 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"220"	"23.3"	"9.17"	"269.50"	"2.90"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13866, Pf13867"	"8819"	"ENSG00000164105"	"SAP30"	"D3DP38; hsa:8819; O75446"	"Retinoblastoma gene in cancer; Notch signaling pathway"	"Potential therapeutics for SARS; HDACs deacetylate histones; NoRC negatively regulates rRNA expression"	"5"	"0"	"8.0"	"18.0"	"10.8"	"20.7"	"10.3"	"7.6"	"26.3"	"30.3"	"59.1"	"168.6"	"254.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBB4"	"Ataxin-10 OS=Homo sapiens OX=9606 GN=ATXN10 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"475"	"53.5"	"5.25"	"554.09"	"2.90"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf09759"	"25814"	"ENSG00000130638"	"ATXN10"	"A6NLC4; B4DG05; hsa:25814; O14998; O15009; Q6I9X4; Q9UBB4"	"Ciliopathies"	""	"1"	"0"	"25.2"	"15.2"	"29.9"	"28.4"	"19.7"	"21.3"	"39.3"	"29.3"	"51.4"	"131.8"	"290.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NC96"	"Adaptin ear-binding coat-associated protein 1 OS=Homo sapiens OX=9606 GN=NECAP1 PE=1 SV=2"	"0.000"	""	"7"	"2"	"3"	"1"	"275"	"29.7"	"6.80"	"614.24"	"2.90"	"2"	"1"	"transport"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf07933"	"25977"	"ENSG00000089818"	"NECAP1"	"hsa:25977; Q2NL73; Q5XG95; Q6NWY6; Q8N153; Q8NC96; Q8NCB0; Q9BU52; Q9Y407"	""	"Golgi Associated Vesicle Biogenesis; Cargo recognition for clathrin-mediated endocytosis"	"3"	"0"	"18.0"	"18.0"	"17.4"	"24.8"	"20.8"	"36.0"	"111.9"	"106.2"	"105.8"	"103.0"	"115.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51178"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1 OS=Homo sapiens OX=9606 GN=PLCD1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"756"	"85.6"	"6.70"	"312.22"	"2.90"	"1"	"1"	"other metabolic processes;transport;signal transduction"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00168, Pf00387, Pf00388, Pf09279"	"5333"	"ENSG00000187091"	"PLCD1"	"B3KR14; hsa:5333; P51178; Q86VN8"	"Myometrial relaxation and contraction pathways; GPR40 pathway; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; Orexin receptor pathway"	"Synthesis of IP3 and IP4 in the cytosol"	"6"	"0"	"34.5"	"31.4"	"52.4"	"54.5"	"45.4"	"53.2"	"92.4"	"97.6"	"114.8"	"272.6"	"360.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBB5"	"Kelch domain-containing protein 4 OS=Homo sapiens OX=9606 GN=KLHDC4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"520"	"57.9"	"5.72"	"265.21"	"2.90"	"1"	"1"	""	""	""	"Pf07646, Pf13418, Pf13854, Pf13964"	"54758"	"ENSG00000104731"	"KLHDC4"	"D3DUN3; D3DUN4; D3DUN5; hsa:54758; Q8TBB5; Q96F29; Q9BVN3"	""	""	"0"	"0"	"4.0"	"0.0"	"4.8"	"3.2"	"3.6"	"0.0"	"7.0"	"9.1"	"16.6"	"38.8"	"46.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y485"	"DmX-like protein 1 OS=Homo sapiens OX=9606 GN=DMXL1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"3027"	"337.6"	"6.34"	"341.62"	"2.89"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf00400, Pf12234"	"1657"	"ENSG00000172869"	"DMXL1"	"hsa:1657; Q9Y485"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYG3"	"MKI67 FHA domain-interacting nucleolar phosphoprotein OS=Homo sapiens OX=9606 GN=NIFK PE=1 SV=1"	"0.000"	""	"5"	"2"	"2"	"2"	"293"	"34.2"	"9.88"	"622.74"	"2.89"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf12196"	"84365"	"ENSG00000155438"	"NIFK"	"A8K788; hsa:84365; Q8TB66; Q96ED4; Q9BYG3"	""	""	"0"	"0"	"123.8"	"163.1"	"158.1"	"184.1"	"136.0"	"139.8"	"228.9"	"216.6"	"272.1"	"561.5"	"691.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00178"	"GTP-binding protein 1 OS=Homo sapiens OX=9606 GN=GTPBP1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"669"	"72.4"	"8.34"	"310.24"	"2.89"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;other cytoplasmic organelle"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"9567"	"ENSG00000100226"	"GTPBP1"	"hsa:9567; O00178; Q6IC67"	""	""	"0"	"0"	"19.6"	"20.1"	"20.7"	"42.5"	"22.6"	"19.1"	"42.3"	"45.3"	"53.3"	"111.1"	"158.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95429"	"BAG family molecular chaperone regulator 4 OS=Homo sapiens OX=9606 GN=BAG4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"457"	"49.6"	"5.12"	"326.28"	"2.88"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf02179"	"9530"	"ENSG00000156735"	"BAG4"	"B4E217; hsa:9530; O95429; O95818"	"Oxidative damage response"	"Regulation of HSF1-mediated heat shock response; Signaling by FGFR1 in disease; Signaling by plasma membrane FGFR1 fusions; TNF signaling"	"5"	"0"	"2.4"	"3.2"	"3.3"	"7.2"	"5.0"	"1.2"	"10.1"	"9.4"	"14.9"	"44.6"	"43.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2K0"	"Translation initiation factor IF-3, mitochondrial OS=Homo sapiens OX=9606 GN=MTIF3 PE=1 SV=4"	"0.000"	""	"5"	"1"	"2"	"1"	"278"	"31.7"	"9.69"	"496.69"	"2.88"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"mitochondrion"	"translation activity;nucleic acid binding activity"	"Pf05198"	"219402"	"ENSG00000122033"	"MTIF3"	"hsa:219402; Q05BL8; Q5W0V0; Q86X68; Q9H2K0"	""	"Mitochondrial translation initiation"	"1"	"0"	"61.2"	"57.5"	"68.0"	"59.7"	"56.1"	"59.6"	"80.8"	"93.3"	"133.4"	"173.2"	"131.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P40424"	"Pre-B-cell leukemia transcription factor 1 OS=Homo sapiens OX=9606 GN=PBX1 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"430"	"46.6"	"7.03"	""	"2.88"	""	"1"	"cell cycle OR cell proliferation;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf03792"	"5087"	"ENSG00000185630"	"PBX1"	"B4DSC1; F5H4U9; hsa:5087; P40424; Q5T488"	"Mesodermal commitment pathway; Pre-implantation embryo; Mammalian disorder of sexual development; Development of ureteric collection system; Markers of kidney cell lineage; Sudden infant death syndrome (SIDS) susceptibility pathways"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; NOTCH3 Intracellular Domain Regulates Transcription; Transcriptional regulation of pluripotent stem cells"	"9"	"0"	"4.9"	"3.4"	"5.2"	"8.0"	"5.7"	"4.3"	"7.6"	"8.2"	"11.2"	"30.5"	"35.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NAN2"	"Mitoguardin 1 OS=Homo sapiens OX=9606 GN=MIGA1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"632"	"71.0"	"5.63"	""	"2.88"	""	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;mitochondrion"	"other molecular function"	"Pf10265"	"374986"	"ENSG00000180488"	"MIGA1"	"hsa:374986; Q6MZG0; Q8NAN2"	""	"Synthesis of PA"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17174"	"Aspartate aminotransferase, cytoplasmic OS=Homo sapiens OX=9606 GN=GOT1 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"413"	"46.2"	"7.01"	"362.89"	"2.88"	"1"	"1"	"other metabolic processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf00155"	"2805"	"ENSG00000120053"	"GOT1"	"B2R6R7; B7Z7E9; hsa:2805; P17174; Q5VW80"	"Alanine and aspartate metabolism; Trans-sulfuration pathway; Amino acid metabolism; NAD metabolism in oncogene-induced senescence and mitochondrial dysfunction-associated senescence; TCA cycle in senescence; Neuroinflammation and glutamatergic signaling; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Gluconeogenesis; Aspartate and asparagine metabolism; Methionine salvage pathway"	"11"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR12"	"PDZ and LIM domain protein 7 OS=Homo sapiens OX=9606 GN=PDLIM7 PE=1 SV=1"	"0.000"	""	"8"	"3"	"4"	"3"	"457"	"49.8"	"8.41"	"934.25"	"2.88"	"3"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595"	"9260"	"ENSG00000196923"	"PDLIM7"	"hsa:9260; Q14250; Q5XG82; Q6NVZ5; Q96C91; Q9BXB8; Q9BXB9; Q9NR12"	"Ebstein-Barr virus LMP1 signaling; GDNF signaling; 5q35 copy number variation"	"RET signaling"	"4"	"0"	"156.3"	"142.3"	"159.8"	"222.7"	"151.7"	"134.1"	"248.3"	"251.4"	"292.7"	"812.0"	"1091.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NB49"	"Phospholipid-transporting ATPase IG OS=Homo sapiens OX=9606 GN=ATP11C PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1132"	"129.4"	"6.67"	"303.01"	"2.88"	"1"	"1"	"cell organization and biogenesis;transport"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00122, Pf13246, Pf16209, Pf16212"	"286410"	"ENSG00000101974"	"ATP11C"	"hsa:286410; Q5JT69; Q5JT70; Q5JT71; Q5JT72; Q5JT73; Q6ZND5; Q6ZU50; Q6ZUP7; Q70IJ9; Q70IK0; Q8NB49; Q8WX24"	"Complement system in neuronal development and plasticity"	"Ion transport by P-type ATPases"	"2"	"0"	"4.1"	"2.5"	"0.0"	"8.3"	"0.0"	"1.6"	"10.0"	"8.2"	"9.5"	"42.3"	"51.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75674"	"TOM1-like protein 1 OS=Homo sapiens OX=9606 GN=TOM1L1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"476"	"53.0"	"5.24"	"337.59"	"2.88"	"1"	"1"	"protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00790, Pf03127"	"10040"	"ENSG00000141198"	"TOM1L1"	"B7Z9E2; hsa:10040; O75674; Q53G06; Q8N749"	""	""	"0"	"0"	"69.3"	"42.0"	"71.4"	"75.1"	"64.3"	"89.0"	"122.1"	"139.8"	"240.1"	"784.9"	"934.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14676"	"Mediator of DNA damage checkpoint protein 1 OS=Homo sapiens OX=9606 GN=MDC1 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2089"	"226.5"	"5.47"	"348.05"	"2.88"	"1"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf00498, Pf16770"	"9656"	"ENSG00000137337; ENSG00000206481; ENSG00000224587; ENSG00000225589; ENSG00000228575; ENSG00000231135; ENSG00000234012; ENSG00000237095"	"MDC1"	"A2AB04; A2BF04; A2RRA8; A7YY86; B0S8A2; hsa:9656; Q0EFC2; Q14676; Q2L6H7; Q2TAZ4; Q5JP55; Q5JP56; Q5ST83; Q68CQ3; Q86Z06; Q96QC2"	"ATM signaling in development and disease ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; NIPBL role in DNA damage - Cornelia de Lange syndrome"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; SUMOylation of DNA damage response and repair proteins; TP53 Regulates Transcription of DNA Repair Genes; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"9"	"0"	"81.0"	"84.0"	"102.3"	"177.8"	"69.2"	"71.5"	"136.0"	"128.9"	"188.6"	"480.2"	"584.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PJG2"	"Mitotic deacetylase-associated SANT domain protein OS=Homo sapiens OX=9606 GN=MIDEAS PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1045"	"114.9"	"9.19"	"257.52"	"2.87"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01448"	"91748"	"ENSG00000156030"	"MIDEAS"	"hsa:91748; Q6PJG2; Q6PK13; Q6PK59; Q6ZS23"	""	""	"0"	"0"	"27.1"	"28.6"	"32.9"	"35.2"	"27.1"	"25.6"	"52.1"	"58.2"	"75.9"	"248.3"	"280.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q10472"	"Polypeptide N-acetylgalactosaminyltransferase 1 OS=Homo sapiens OX=9606 GN=GALNT1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"559"	"64.2"	"7.72"	""	"2.87"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00535, Pf00652"	"2589"	"ENSG00000141429"	"GALNT1"	"hsa:2589; Q10472; Q86TJ7; Q9UM86"	"Metabolism of sphingolipids in ER and Golgi apparatus"	"COPI-independent Golgi-to-ER retrograde traffic; O-linked glycosylation of mucins; Maturation of protein 3a; Maturation of protein 3a"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NUP7"	"tRNA:m(4)X modification enzyme TRM13 homolog OS=Homo sapiens OX=9606 GN=TRMT13 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"481"	"54.2"	"8.09"	"335.61"	"2.86"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	""	"other molecular function"	"Pf05206, Pf05253, Pf11722"	"54482"	"ENSG00000122435"	"TRMT13"	"hsa:54482; Q5VVL0; Q9NUP7; Q9NW65"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52732"	"Kinesin-like protein KIF11 OS=Homo sapiens OX=9606 GN=KIF11 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1056"	"119.1"	"5.64"	"236.17"	"2.86"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf13931"	"3832"	"ENSG00000138160"	"KIF11"	"A0AV49; B2RMV3; hsa:3832; P52732; Q15716; Q5VWX0"	""	"COPI-dependent Golgi-to-ER retrograde traffic; MHC class II antigen presentation; Kinesins"	"3"	"0"	"3.9"	"3.6"	"17.9"	"0.0"	"3.9"	"4.4"	"12.3"	"5.0"	"12.3"	"24.8"	"34.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13823"	"Nucleolar GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GNL2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"731"	"83.6"	"9.25"	"300.30"	"2.86"	"1"	"1"	"other biological processes"	"nucleus"	"other molecular function"	"Pf01926, Pf08153"	"29889"	"ENSG00000134697"	"GNL2"	"hsa:29889; Q13823; Q9BWN7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95671"	"Probable bifunctional dTTP/UTP pyrophosphatase/methyltransferase protein OS=Homo sapiens OX=9606 GN=ASMTL PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"621"	"68.8"	"6.07"	"387.31"	"2.86"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00891, Pf02545, Pf16864"	"8623"	"ENSG00000169093"	"ASMTL"	"B4DX75; F5GXH4; hsa:8623; J3JS33; O95671; Q5JQ53; Q8NBH5; Q96G02; Q9BUL6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N668"	"COMM domain-containing protein 1 OS=Homo sapiens OX=9606 GN=COMMD1 PE=1 SV=1"	""	""	"11"	"1"	"1"	"1"	"190"	"21.2"	"6.20"	""	"2.85"	""	"1"	"DNA metabolism;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf07258, Pf17221"	"150684"	"ENSG00000173163"	"COMMD1"	"B4DFQ4; hsa:150684; Q8N668; Q96GS0"	"Copper homeostasis; 1p36 copy number variation syndrome"	"Neddylation"	"3"	"0"	"7.0"	"3.5"	"9.9"	"16.4"	"5.3"	"6.7"	"15.4"	"15.1"	"15.5"	"56.0"	"99.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T23"	"Remodeling and spacing factor 1 OS=Homo sapiens OX=9606 GN=RSF1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1441"	"163.7"	"5.01"	"236.78"	"2.85"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf00628, Pf15612"	"51773"	"ENSG00000048649"	"RSF1"	"hsa:51773; Q86X86; Q96T23; Q9H3L8; Q9NVZ8; Q9NYU0"	""	"Deposition of new CENPA-containing nucleosomes at the centromere"	"1"	"0"	"10.8"	"5.6"	"6.4"	"8.2"	"9.9"	"9.5"	"18.3"	"23.5"	"28.7"	"108.0"	"209.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UI95"	"Mitotic spindle assembly checkpoint protein MAD2B OS=Homo sapiens OX=9606 GN=MAD2L2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"211"	"24.3"	"6.52"	"373.00"	"2.85"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf02301"	"10459"	"ENSG00000116670"	"MAD2L2"	"B3KNE3; hsa:10459; Q5TGW7; Q9UI95; Q9UNA7; Q9Y6I6"	"Cell cycle; 10q22q23 copy number variation"	"Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI"	"5"	"0"	"67.1"	"49.8"	"103.0"	"94.7"	"67.7"	"78.6"	"100.5"	"99.3"	"152.3"	"374.6"	"559.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96L92"	"Sorting nexin-27 OS=Homo sapiens OX=9606 GN=SNX27 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"541"	"61.2"	"6.49"	"578.43"	"2.85"	"2"	"1"	"transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00595, Pf00787, Pf00788"	"81609"	"ENSG00000143376"	"SNX27"	"hsa:81609; Q32Q36; Q4AEJ5; Q5VWB0; Q5VWB1; Q5VWB2; Q6IPP6; Q86UB1; Q96D79; Q96L92; Q9H3K8"	""	""	"0"	"0"	"106.8"	"87.6"	"130.4"	"137.4"	"106.2"	"99.6"	"181.4"	"172.2"	"212.9"	"1077.8"	"1613.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15648"	"Mediator of RNA polymerase II transcription subunit 1 OS=Homo sapiens OX=9606 GN=MED1 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1581"	"168.4"	"8.73"	"628.07"	"2.84"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"nucleus"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf10744"	"5469"	"ENSG00000125686"	"MED1"	"A2RRQ6; hsa:5469; O43810; O75447; Q15648; Q6P9H7; Q6PK58; Q9HD39"	"Energy metabolism; H19 action Rb-E2F1 signaling and CDK-Beta-catenin activity; Non-genomic actions of 1,25 dihydroxyvitamin D3; 17q12 copy number variation syndrome"	"Cytoprotection by HMOX1; Estrogen-dependent gene expression; Transcriptional activation of mitochondrial biogenesis; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Nuclear Receptor transcription pathway; Activation of gene expression by SREBF (SREBP); RORA activates gene expression"	"17"	"0"	"69.5"	"63.4"	"100.0"	"98.5"	"89.4"	"82.9"	"134.7"	"153.7"	"215.2"	"302.6"	"340.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQT8"	"Kinesin-like protein KIF13B OS=Homo sapiens OX=9606 GN=KIF13B PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1826"	"202.7"	"5.88"	"272.24"	"2.84"	"1"	"1"	"transport;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf01302, Pf12423, Pf12473, Pf16183"	"23303"	"ENSG00000197892"	"KIF13B"	"B4DGY5; B5MC45; F8VPJ2; hsa:23303; O75134; Q9BYJ6; Q9NQT8"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	"5.3"	"3.0"	"2.5"	"8.8"	"5.6"	"3.3"	"9.5"	"11.7"	"19.1"	"35.5"	"51.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P49023"	"Paxillin OS=Homo sapiens OX=9606 GN=PXN PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"591"	"64.5"	"6.19"	"299.14"	"2.84"	"1"	"1"	"cell adhesion;cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00412, Pf03535"	"5829"	"ENSG00000089159"	"PXN"	"B2RAI3; B7ZMB4; hsa:5829; O14970; O14971; O60360; P49023; Q5HYA4"	"Integrin-mediated cell adhesion; Prolactin signaling pathway; Androgen receptor network in prostate cancer; Oncostatin M signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Gastrin signaling pathway; 3q29 copy number variation syndrome; Regulation of actin cytoskeleton; GDNF signaling"	"VEGFA-VEGFR2 Pathway; GAB1 signalosome; Smooth Muscle Contraction; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases; Localization of the PINCH-ILK-PARVIN complex to focal adhesions; Regulation of cytoskeletal remodeling and cell spreading by IPP complex components"	"20"	"0"	"43.3"	"25.7"	"63.3"	"52.8"	"36.5"	"41.3"	"69.0"	"58.9"	"69.5"	"112.6"	"150.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H063"	"Repressor of RNA polymerase III transcription MAF1 homolog OS=Homo sapiens OX=9606 GN=MAF1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"256"	"28.8"	"4.55"	"263.79"	"2.84"	"1"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf09174"	"84232"	"ENSG00000179632"	"MAF1"	"D3DWL4; hsa:84232; Q9H063"	""	"Regulation of PTEN gene transcription"	"1"	"0"	"16.5"	"18.2"	"28.5"	"27.7"	"32.5"	"25.9"	"50.8"	"43.9"	"66.2"	"289.5"	"407.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19823"	"Inter-alpha-trypsin inhibitor heavy chain H2 OS=Homo sapiens OX=9606 GN=ITIH2 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"946"	"106.4"	"6.86"	"603.12"	"2.83"	"2"	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;ER/Golgi"	"enzyme regulator activity;other molecular function"	"Pf00092, Pf06668, Pf08487"	"3698"	"ENSG00000151655"	"ITIH2"	"hsa:3698; P19823; Q14659; Q15484; Q5T986"	""	"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"2"	"0"	"4.6"	"0.0"	"3.7"	"4.5"	"3.1"	"6.4"	"8.1"	"5.9"	"11.2"	"24.3"	"44.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96IJ6"	"Mannose-1-phosphate guanyltransferase alpha OS=Homo sapiens OX=9606 GN=GMPPA PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"420"	"46.3"	"7.21"	"357.93"	"2.83"	"1"	"1"	"other metabolic processes"	"other cell component"	"other molecular function"	"Pf00483"	"29926"	"ENSG00000144591"	"GMPPA"	"A6NJ74; A8K3Q6; B3KMT4; hsa:29926; Q53GI0; Q96IJ6; Q9NWC3; Q9Y5P5"	"N-glycan biosynthesis"	"Synthesis of GDP-mannose"	"2"	"0"	"28.0"	"26.9"	"40.1"	"53.8"	"22.5"	"19.5"	"61.5"	"63.8"	"67.6"	"218.0"	"354.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IZH2"	"5'-3' exoribonuclease 1 OS=Homo sapiens OX=9606 GN=XRN1 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1706"	"194.0"	"7.21"	""	"2.83"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03159, Pf17846, Pf18129, Pf18332, Pf18334"	"54464"	"ENSG00000114127"	"XRN1"	"hsa:54464; Q4G0S3; Q68D88; Q6AI24; Q6MZS8; Q86WS7; Q8IZH2; Q8N8U4; Q9UF39"	"miRNA degrading enzymes"	"mRNA decay by 5' to 3' exoribonuclease; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"4"	"0"	"7.5"	"6.4"	"17.0"	"13.4"	"6.5"	"7.7"	"15.4"	"17.1"	"19.2"	"50.8"	"66.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P52735"	"Guanine nucleotide exchange factor VAV2 OS=Homo sapiens OX=9606 GN=VAV2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"878"	"101.2"	"7.08"	"331.01"	"2.83"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00017, Pf00130, Pf00169, Pf00307, Pf00621, Pf07653"	"7410"	"ENSG00000160293"	"VAV2"	"A2RUM4; A8MQ12; B6ZDF5; hsa:7410; P52735; Q5SYV3; Q5SYV4; Q5SYV5; Q6N012; Q6PIJ9; Q6Q317"	"Integrin-mediated cell adhesion; Prolactin signaling pathway; B cell receptor signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Focal adhesion; Hepatitis C and hepatocellular carcinoma; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Microglia pathogen phagocytosis pathway; Ebola virus infection in host; EGF/EGFR signaling pathway; 16p11.2 distal deletion syndrome; GDNF signaling"	"EPH-ephrin mediated repulsion of cells; Regulation of actin dynamics for phagocytic cup formation; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated phagocytosis; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOB GTPase cycle; GPVI-mediated activation cascade; DAP12 signaling; Signal transduction by L1; Azathioprine ADME; VEGFR2 mediated vascular permeability"	"34"	"0"	"3.4"	"1.8"	"3.9"	"7.8"	"3.9"	"2.5"	"8.6"	"12.3"	"24.4"	"90.4"	"122.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCE1"	"Helicase MOV-10 OS=Homo sapiens OX=9606 GN=MOV10 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1003"	"113.6"	"8.82"	"361.82"	"2.82"	"1"	"1"	"stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13087, Pf13604"	"4343"	"ENSG00000155363"	"MOV10"	"hsa:4343; Q5JR03; Q8TEF0; Q9BSY3; Q9BUJ9; Q9HCE1"	"VEGFA-VEGFR2 signaling"	"TP53 Regulates Metabolic Genes; MAPK6/MAPK4 signaling; Oxidative Stress Induced Senescence; Estrogen-dependent gene expression; Pre-NOTCH Transcription and Translation; RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function; Ca2+ pathway; Oncogene Induced Senescence; Transcriptional Regulation by VENTX; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; Regulation of RUNX1 Expression and Activity; Regulation of CDH11 mRNA translation by microRNAs; Regulation of NPAS4 mRNA translation; Competing endogenous RNAs (ceRNAs) regulate PTEN translation"	"18"	"0"	"24.1"	"20.0"	"28.4"	"45.1"	"21.5"	"24.1"	"51.2"	"59.3"	"77.9"	"196.2"	"258.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P035"	"Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase 3 OS=Homo sapiens OX=9606 GN=HACD3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"362"	"43.1"	"8.94"	"367.23"	"2.82"	"1"	"1"	"other metabolic processes;stress response;signal transduction;other biological processes"	"other membranes;ER/Golgi;nucleus"	"enzyme regulator activity;other molecular function"	"Pf04387"	"51495"	"ENSG00000074696"	"HACD3"	"A0PJA1; B4DRF4; hsa:51495; Q280Z3; Q6PD63; Q8IUI5; Q8NC86; Q8NCB1; Q96T12; Q9NQA7; Q9P035"	""	"Synthesis of very long-chain fatty acyl-CoAs"	"1"	"0"	"62.3"	"50.7"	"73.8"	"74.6"	"57.7"	"64.3"	"105.7"	"112.1"	"165.3"	"461.6"	"701.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43617"	"Trafficking protein particle complex subunit 3 OS=Homo sapiens OX=9606 GN=TRAPPC3 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"180"	"20.3"	"4.96"	"260.56"	"2.82"	"1"	"1"	"cell organization and biogenesis;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf04051"	"27095"	"ENSG00000054116"	"TRAPPC3"	"A6NDN0; B2RDN2; D3DPS2; hsa:27095; O43617"	""	"RAB GEFs exchange GTP for GDP on RABs; COPII-mediated vesicle transport"	"2"	"0"	"23.9"	"23.4"	"31.8"	"30.1"	"21.9"	"35.2"	"71.1"	"80.0"	"130.8"	"418.7"	"643.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H1Z4"	"WD repeat-containing protein 13 OS=Homo sapiens OX=9606 GN=WDR13 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"485"	"53.7"	"9.14"	""	"2.81"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"61.8"	"50.7"	"66.5"	"82.3"	"51.9"	"59.3"	"114.8"	"105.7"	"148.7"	"310.0"	"455.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H2M9"	"Rab3 GTPase-activating protein non-catalytic subunit OS=Homo sapiens OX=9606 GN=RAB3GAP2 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"1393"	"155.9"	"5.62"	"259.75"	"2.81"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf14655, Pf14656"	"25782"	"ENSG00000118873"	"RAB3GAP2"	"A6H8V0; hsa:25782; O75872; Q9H2M9; Q9HAB0; Q9UFJ7; Q9UQ15"	""	"RAB GEFs exchange GTP for GDP on RABs; COPI-independent Golgi-to-ER retrograde traffic"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0B6"	"Kinesin light chain 2 OS=Homo sapiens OX=9606 GN=KLC2 PE=1 SV=1"	"0.000"	""	"5"	"2"	"3"	"2"	"622"	"68.9"	"7.15"	"853.08"	"2.80"	"2"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity"	"Pf13424"	"64837"	"ENSG00000174996"	"KLC2"	"A8MXL7; B2RDY4; hsa:64837; Q9H0B6; Q9H9C8; Q9HA20"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	"MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins; RHO GTPases activate KTN1"	"6"	"0"	"85.2"	"61.3"	"121.8"	"116.4"	"84.2"	"90.6"	"167.0"	"164.4"	"244.6"	"622.1"	"752.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0U9"	"Testis-specific Y-encoded-like protein 1 OS=Homo sapiens OX=9606 GN=TSPYL1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"437"	"49.2"	"5.45"	"326.03"	"2.80"	"1"	"1"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"7259"	"ENSG00000189241"	"TSPYL1"	"hsa:7259; O75885; Q5TFE6; Q9H0U9"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95373"	"Importin-7 OS=Homo sapiens OX=9606 GN=IPO7 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"1038"	"119.4"	"4.82"	"252.91"	"2.80"	"1"	"1"	"stress response;transport;other biological processes"	"cytosol;nucleus"	"enzyme regulator activity;other molecular function"	"Pf03810, Pf08506"	"10527"	"ENSG00000205339"	"IPO7"	"A6NNM5; B2R786; hsa:10527; O95373; Q1RMF7; Q9H177; Q9NTE3"	""	""	"0"	"0"	"4.8"	"2.5"	"5.6"	"0.0"	"2.6"	"0.0"	"7.5"	"6.5"	"15.8"	"51.2"	"95.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BUK6"	"Protein misato homolog 1 OS=Homo sapiens OX=9606 GN=MSTO1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"570"	"61.8"	"6.11"	"282.73"	"2.79"	"1"	"1"	"cell organization and biogenesis"	"other membranes;cytosol;mitochondrion;other cell component"	""	"Pf10644, Pf14881"	"55154"	"ENSG00000125459"	"MSTO1"	"hsa:55154; Q53GR8; Q5CZ69; Q5T717; Q68CT6; Q7LBZ8; Q7Z3M7; Q7Z558; Q8TE05; Q9BUK6; Q9NQX2; Q9NVU4"	""	""	"0"	"0"	"11.4"	"9.9"	"19.7"	"22.6"	"16.1"	"18.9"	"26.3"	"26.1"	"31.6"	"66.5"	"75.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BYG5"	"Partitioning defective 6 homolog beta OS=Homo sapiens OX=9606 GN=PARD6B PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"372"	"41.2"	"5.58"	"333.31"	"2.79"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	""	"Pf00564, Pf00595"	"84612"	"ENSG00000124171"	"PARD6B"	"A2A2A7; hsa:84612; Q9BYG5; Q9Y510"	"Complement system in neuronal development and plasticity; 1p36 copy number variation syndrome"	"RHOV GTPase cycle; Tight junction interactions"	"4"	"0"	"60.0"	"130.3"	"85.2"	"101.4"	"67.0"	"77.1"	"118.7"	"144.5"	"185.2"	"463.2"	"497.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2D1"	"Chromodomain-helicase-DNA-binding protein 7 OS=Homo sapiens OX=9606 GN=CHD7 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"2997"	"335.7"	"6.34"	"599.76"	"2.78"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf07533"	"55636"	"ENSG00000171316"	"CHD7"	"D0VBA5; E9PNZ2; hsa:55636; Q05DI5; Q2TAN4; Q66K35; Q7Z6C0; Q7Z7Q2; Q9NXA0; Q9NXA3; Q9P2D1"	"Kallmann syndrome"	""	"1"	"0"	"48.7"	"26.2"	"61.7"	"64.2"	"56.4"	"48.3"	"69.0"	"57.7"	"77.2"	"81.0"	"145.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93050"	"V-type proton ATPase 116 kDa subunit a isoform 1 OS=Homo sapiens OX=9606 GN=ATP6V0A1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"837"	"96.4"	"6.43"	"277.76"	"2.78"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf01496"	"535"	"ENSG00000033627"	"ATP6V0A1"	"B7Z3B7; hsa:535; Q8N5G7; Q93050; Q9NSX0"	""	"Neutrophil degranulation; ROS and RNS production in phagocytes; Insulin receptor recycling; Transferrin endocytosis and recycling; Ion channel transport"	"5"	"0"	"3.1"	"0.0"	"3.3"	"6.8"	"2.7"	"3.6"	"6.5"	"6.4"	"12.1"	"34.2"	"55.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W34"	"Archaemetzincin-2 OS=Homo sapiens OX=9606 GN=AMZ2 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"360"	"41.2"	"8.15"	"410.50"	"2.78"	"1"	"1"	"protein metabolism"	""	"other molecular function"	"Pf07998"	"51321"	"ENSG00000196704"	"AMZ2"	"A6NLD9; B3KR44; hsa:51321; Q5XKF1; Q86W34; Q9NZE2"	""	""	"0"	"0"	"9.3"	"12.0"	"6.7"	"16.3"	"7.9"	"9.0"	"18.0"	"43.6"	"28.6"	"102.5"	"43.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q709F0"	"Acyl-CoA dehydrogenase family member 11 OS=Homo sapiens OX=9606 GN=ACAD11 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"780"	"87.2"	"8.02"	"365.85"	"2.78"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00441, Pf01636, Pf02770, Pf02771"	"84129"	"ENSG00000240303"	"ACAD11"	"hsa:84129; Q08AF0; Q658N9; Q658Y2; Q6ZND2; Q709F0; Q8WUT6; Q9H9R3"	"p53 transcriptional gene network"	"Mitochondrial Fatty Acid Beta-Oxidation"	"2"	"0"	"39.3"	"29.0"	"41.0"	"47.6"	"34.4"	"32.0"	"57.1"	"59.0"	"103.3"	"310.0"	"435.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVQ7"	"Spermatogenesis-associated protein 5-like protein 1 OS=Homo sapiens OX=9606 GN=SPATA5L1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"753"	"80.7"	"8.09"	"577.05"	"2.77"	"2"	"1"	"other biological processes"	"cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00004, Pf17862"	"79029"	"ENSG00000171763"	"AFG2B"	"C9JHR5; hsa:79029; Q9BVQ7; Q9H8W7; Q9HA41"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TDJ6"	"DmX-like protein 2 OS=Homo sapiens OX=9606 GN=DMXL2 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"3036"	"339.4"	"6.38"	""	"2.77"	""	"1"	"other biological processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00400, Pf12234"	"23312"	"ENSG00000104093"	"DMXL2"	"B2RTR3; B7ZMH3; F5GWF1; hsa:23312; O94938; Q8TDJ6"	""	""	"0"	"0"	"290.1"	"67.9"	"402.3"	"296.7"	"265.8"	"279.5"	"297.2"	"207.8"	"281.3"	"416.4"	"936.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P22735"	"Protein-glutamine gamma-glutamyltransferase K OS=Homo sapiens OX=9606 GN=TGM1 PE=1 SV=4"	"0.001"	""	"1"	"1"	"2"	"1"	"817"	"89.7"	"6.04"	"236.55"	"2.77"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol"	"other molecular function"	"Pf00868, Pf00927, Pf01841"	"7051"	"ENSG00000092295; ENSG00000285348"	"TGM1"	"B4DWR7; hsa:7051; P22735; Q197M4"	""	"Formation of the cornified envelope"	"1"	"0"	"17.2"	"22.3"	"168.6"	"5.3"	"9.3"	"8.4"	"24.9"	"19.5"	"27.7"	"46.1"	"47.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92540"	"Protein SMG7 OS=Homo sapiens OX=9606 GN=SMG7 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1137"	"127.2"	"8.72"	"285.13"	"2.77"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf10373, Pf10374"	"9887"	"ENSG00000116698"	"SMG7"	"B4DRB2; E9PCI0; E9PEH2; hsa:9887; Q5T1Q0; Q6PIE0; Q7Z7H9; Q8IXC1; Q8IXC2; Q92540"	""	"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)"	"1"	"0"	"11.5"	"4.3"	"9.7"	"12.0"	"11.9"	"9.8"	"13.9"	"16.6"	"16.5"	"38.4"	"54.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TC07"	"TBC1 domain family member 15 OS=Homo sapiens OX=9606 GN=TBC1D15 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"691"	"79.4"	"5.67"	""	"2.76"	""	"1"	"other biological processes"	"non-structural extracellular;other cell component"	"enzyme regulator activity"	"Pf00566, Pf12068"	"64786"	"ENSG00000121749"	"TBC1D15"	"B4DMT9; B9A6L6; hsa:64786; J3KNI9; Q8TC07; Q9HA83"	""	"TBC/RABGAPs"	"1"	"0"	"5.8"	"5.5"	"7.6"	"6.9"	"7.1"	"6.7"	"9.7"	"13.0"	"20.3"	"50.1"	"62.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51587"	"Breast cancer type 2 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA2 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"3418"	"384.0"	"6.71"	"264.53"	"2.76"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"4.0"	"5.5"	"6.9"	"8.1"	"6.5"	"5.0"	"9.0"	"10.1"	"14.6"	"28.1"	"36.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH99"	"SUN domain-containing protein 2 OS=Homo sapiens OX=9606 GN=SUN2 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"717"	"80.3"	"6.73"	"271.81"	"2.76"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"other membranes;nucleus;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf07738, Pf18580"	"25777"	"ENSG00000100242"	"SUN2"	"B0QY62; hsa:25777; O75156; Q2NKN8; Q2T9F7; Q504T5; Q6B4H1; Q7Z3E3; Q9UH99"	""	"Meiotic synapsis"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6PGP7"	"Tetratricopeptide repeat protein 37 OS=Homo sapiens OX=9606 GN=TTC37 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1564"	"175.4"	"7.53"	""	"2.76"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	""	"Pf13181, Pf13432"	"9652"	"ENSG00000198677"	"SKIC3"	"hsa:9652; O15077; Q6PGP7; Q6PJI3"	""	"mRNA decay by 3' to 5' exoribonuclease"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRV8"	"Suppressor of IKBKE 1 OS=Homo sapiens OX=9606 GN=SIKE1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"207"	"23.7"	"5.21"	"298.50"	"2.75"	"1"	"1"	""	"cytosol"	"other molecular function"	"Pf05769"	"80143"	"ENSG00000052723"	"SIKE1"	"hsa:80143; Q5TEZ7; Q5TEZ9; Q68DZ4; Q9BRV8; Q9H778"	"Novel intracellular components of RIG-I-like receptor pathway"	"SARS-CoV-2 activates/modulates innate and adaptive immune responses; SARS-CoV-1 activates/modulates innate immune responses; TRAF3-dependent IRF activation pathway; TRAF6 mediated IRF7 activation"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96P48"	"Arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ARAP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1450"	"162.1"	"6.23"	"306.75"	"2.75"	"1"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf00536, Pf00620, Pf00788, Pf01412"	"116985"	"ENSG00000186635"	"ARAP1"	"A3KLL7; B2RTS2; hsa:116985; O94879; Q4LDD5; Q59FI7; Q6PHS3; Q8WU51; Q96HP6; Q96L71; Q96P48"	""	"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CP2"	"FLYWCH family member 2 OS=Homo sapiens OX=9606 GN=FLYWCH2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"140"	"14.6"	"8.46"	"368.97"	"2.75"	"1"	"1"	""	""	""	"Pf15423"	"114984"	"ENSG00000162076"	"FLYWCH2"	"hsa:114984; Q96CP2"	""	""	"0"	"0"	"61.1"	"60.7"	"60.4"	"70.2"	"59.6"	"66.0"	"161.3"	"174.9"	"302.8"	"627.5"	"735.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969E8"	"Pre-rRNA-processing protein TSR2 homolog OS=Homo sapiens OX=9606 GN=TSR2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"191"	"20.9"	"4.39"	"284.85"	"2.74"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf10273"	"90121"	"ENSG00000158526"	"TSR2"	"hsa:90121; Q969E8"	""	""	"0"	"0"	"155.0"	"127.2"	"155.8"	"176.7"	"121.8"	"96.8"	"222.2"	"214.9"	"281.8"	"987.2"	"1059.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P84101"	"Small EDRK-rich factor 2 OS=Homo sapiens OX=9606 GN=SERF2 PE=1 SV=1"	"0.000"	""	"14"	"1"	"2"	"1"	"59"	"6.9"	"10.45"	"337.81"	"2.74"	"1"	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf04419"	"10169"	"ENSG00000140264"	"SERF2"	"A6NL45; B5MCG1; B9A026; hsa:10169; O75918; O88891; P84101; Q9BZH7"	""	""	"0"	"0"	"163.9"	"66.5"	"128.0"	"145.0"	"100.3"	"93.9"	"132.1"	"135.6"	"169.7"	"201.3"	"248.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAS0"	"Protein Njmu-R1 OS=Homo sapiens OX=9606 GN=C17orf75 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"396"	"44.6"	"5.03"	"350.88"	"2.74"	"1"	"1"	"cell organization and biogenesis;transport"	"ER/Golgi;other cell component"	""	"Pf15053"	"64149"	"ENSG00000108666"	"C17orf75"	"hsa:64149; Q7Z2H4; Q9HAS0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16537"	"Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform OS=Homo sapiens OX=9606 GN=PPP2R5E PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"467"	"54.7"	"6.95"	"298.21"	"2.74"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf01603"	"5529"	"ENSG00000154001"	"PPP2R5E"	"A4FU37; B7ZAW5; B7ZKK8; B7ZKK9; hsa:5529; J3KQN6; Q16537; Q52LW4"	"Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Wnt signaling pathway and pluripotency; PI3K-Akt signaling pathway; Glycogen synthesis and degradation; Cohesin complex - Cornelia de Lange syndrome; DNA damage response (only ATM dependent)"	"RHO GTPases Activate Formins; Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Negative regulation of MAPK pathway; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Disassembly of the destruction complex and recruitment of AXIN to the membrane; RAF activation; Beta-catenin phosphorylation cascade; Signaling by GSK3beta mutants; CTNNB1 S33 mutants aren't phosphorylated; CTNNB1 S37 mutants aren't phosphorylated; CTNNB1 S45 mutants aren't phosphorylated; CTNNB1 T41 mutants aren't phosphorylated; APC truncation mutants have impaired AXIN binding; AXIN missense mutants destabilize the destruction complex; Truncations of AMER1 destabilize the destruction complex; Platelet sensitization by LDL; CTLA4 inhibitory signaling"	"28"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8TDR2"	"Serine/threonine-protein kinase 35 OS=Homo sapiens OX=9606 GN=STK35 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"534"	"58.0"	"9.74"	""	"2.74"	""	"1"	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"140901"	"ENSG00000125834"	"STK35"	"B2RBM3; C7ENV8; hsa:140901; Q2NKW6; Q5T3R1; Q5T3R2; Q8TDR2; Q96AB4; Q9BZ06"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35610"	"Sterol O-acyltransferase 1 OS=Homo sapiens OX=9606 GN=SOAT1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"550"	"64.7"	"8.94"	"373.97"	"2.74"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03062"	"6646"	"ENSG00000057252"	"SOAT1"	"A6NC40; A8K3P4; A9Z1V7; B4DU95; hsa:6646; P35610; Q5T0X4; Q8N1E4"	"Statin inhibition of cholesterol production; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism"	"LDL clearance"	"4"	"0"	"29.2"	"29.3"	"30.8"	"44.3"	"32.3"	"28.1"	"46.1"	"47.4"	"78.8"	"132.6"	"166.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12830"	"Nucleosome-remodeling factor subunit BPTF OS=Homo sapiens OX=9606 GN=BPTF PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"3046"	"338.1"	"6.54"	"286.28"	"2.74"	"1"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00439, Pf00628, Pf02791, Pf15613"	"2186"	"ENSG00000171634"	"BPTF"	"hsa:2186; Q12830; Q6NX67; Q7Z7D6; Q9UIG2"	"Endoderm differentiation; 16p11.2 proximal deletion syndrome"	""	"2"	"0"	"204.5"	"192.0"	"219.6"	"254.2"	"201.8"	"188.2"	"319.3"	"325.1"	"425.7"	"1058.1"	"1360.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H089"	"Large subunit GTPase 1 homolog OS=Homo sapiens OX=9606 GN=LSG1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"658"	"75.2"	"6.38"	"301.67"	"2.74"	"1"	"1"	"transport"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf01926"	"55341"	"ENSG00000041802"	"LSG1"	"A0JLT4; A0PJK3; A6NI18; hsa:55341; Q7L9H8; Q9H089; Q9NUK8"	""	""	"0"	"0"	"48.4"	"44.2"	"49.5"	"73.9"	"49.2"	"51.8"	"68.8"	"74.3"	"97.8"	"220.9"	"326.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3Q1"	"Cdc42 effector protein 4 OS=Homo sapiens OX=9606 GN=CDC42EP4 PE=1 SV=1"	"0.000"	""	"9"	"2"	"3"	"2"	"356"	"38.0"	"5.19"	"1093.96"	"2.74"	"2"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00786, Pf14957"	"23580"	"ENSG00000179604"	"CDC42EP4"	"B3KUS7; hsa:23580; O95828; Q96FT3; Q9H3Q1"	""	"CDC42 GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RHOQ GTPase cycle"	"4"	"0"	"95.3"	"73.6"	"105.7"	"126.2"	"91.6"	"89.0"	"136.7"	"138.4"	"179.4"	"265.6"	"288.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"L0R819"	"ASNSD1 upstream open reading frame protein OS=Homo sapiens OX=9606 GN=ASDURF PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"96"	"11.2"	"8.88"	"389.15"	"2.73"	"1"	"1"	"other biological processes"	"other cell component"	""	""	""	"ENSG00000286053"	"ASDURF"	"L0R819"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYZ3"	"G2 and S phase-expressed protein 1 OS=Homo sapiens OX=9606 GN=GTSE1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"720"	"76.6"	"9.39"	"316.35"	"2.73"	"1"	"1"	"cell cycle OR cell proliferation;stress response;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus"	"cytoskeletal activity"	"Pf15259"	"51512"	"ENSG00000075218"	"GTSE1"	"B0QYM3; hsa:51512; Q20WK2; Q53GX5; Q5R3I6; Q6DHX4; Q9BRE0; Q9NYZ3; Q9UGZ9; Q9Y557"	""	"G2/M Checkpoints; The role of GTSE1 in G2/M progression after G2 checkpoint"	"2"	"0"	"23.0"	"12.0"	"36.7"	"39.9"	"20.8"	"18.2"	"28.7"	"28.0"	"27.5"	"44.1"	"56.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6J9"	"TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L OS=Homo sapiens OX=9606 GN=TAF6L PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"622"	"67.8"	"8.97"	"307.82"	"2.73"	"1"	"1"	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02969, Pf07571"	"10629"	"ENSG00000162227"	"TAF6L"	"B2RAT0; hsa:10629; Q96HA6; Q9Y6J9"	""	"HATs acetylate histones"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UHV9"	"Prefoldin subunit 2 OS=Homo sapiens OX=9606 GN=PFDN2 PE=1 SV=1"	"0.001"	""	"6"	"1"	"2"	"1"	"154"	"16.6"	"6.58"	"231.83"	"2.72"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf01920"	"5202"	"ENSG00000143256"	"PFDN2"	"hsa:5202; Q9P0P7; Q9UHV9; Q9UN05"	"Cellular proteostasis"	"Prefoldin mediated transfer of substrate  to CCT/TriC"	"2"	"0"	"35.1"	"28.9"	"50.6"	"75.0"	"38.9"	"41.4"	"66.9"	"80.8"	"121.5"	"351.7"	"515.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00401"	"Neural Wiskott-Aldrich syndrome protein OS=Homo sapiens OX=9606 GN=WASL PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"505"	"54.8"	"7.93"	"337.13"	"2.72"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity"	"Pf00568, Pf00786, Pf02205"	"8976"	"ENSG00000106299"	"WASL"	"A1JUI9; hsa:8976; O00401; Q7Z746"	"Pathogenic Escherichia coli infection; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Chemokine signaling pathway; G13 signaling pathway"	"Clathrin-mediated endocytosis; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOQ GTPase cycle; RHO GTPases Activate WASPs and WAVEs; RHOJ GTPase cycle; RHOV GTPase cycle; NOSTRIN mediated eNOS trafficking; Nephrin family interactions; EPHB-mediated forward signaling; DCC mediated attractive signaling"	"17"	"0"	"79.8"	"80.8"	"75.4"	"110.7"	"82.9"	"66.1"	"129.9"	"132.1"	"215.9"	"405.9"	"483.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15347"	"High mobility group protein B3 OS=Homo sapiens OX=9606 GN=HMGB3 PE=1 SV=4"	"0.000"	""	"11"	"2"	"3"	"2"	"200"	"23.0"	"8.37"	"977.03"	"2.72"	"2"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00505, Pf09011"	"3149"	"ENSG00000029993"	"HMGB3"	"hsa:3149; O15347; O95556; Q6NS40"	""	""	"0"	"0"	"276.9"	"239.1"	"278.3"	"300.8"	"248.2"	"266.4"	"414.1"	"455.0"	"627.8"	"1436.9"	"1615.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7L5Y9"	"E3 ubiquitin-protein transferase MAEA OS=Homo sapiens OX=9606 GN=MAEA PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"396"	"45.3"	"8.69"	""	"2.72"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10607"	"10296"	"ENSG00000090316"	"MAEA"	"hsa:10296; O95285; Q5JB54; Q6ZRD6; Q7L5Y9; Q9BQ11; Q9H9V6; Q9H9Z4; Q9NW84"	"Ciliary landscape"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q05655"	"Protein kinase C delta type OS=Homo sapiens OX=9606 GN=PRKCD PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"676"	"77.5"	"7.75"	"292.83"	"2.72"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00130, Pf00433"	"5580"	"ENSG00000163932"	"PRKCD"	"B0KZ81; B2R834; hsa:5580; Q05655; Q15144; Q86XJ6"	"Type II diabetes mellitus; Glioblastoma signaling pathways; B cell receptor signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Myometrial relaxation and contraction pathways; G protein signaling pathways; IL6 signaling pathway; MAPK signaling pathway; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Wnt signaling pathway and pluripotency; Pancreatic adenocarcinoma pathway; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Hippo signaling regulation pathways; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; IL-18 signaling pathway; Osteoblast differentiation and related diseases; Insulin signaling; Kisspeptin/kisspeptin receptor system in the ovary; Galanin receptor pathway; Orexin receptor pathway; CCL18 signaling pathway; Chronic hyperglycemia impairment of neuron function; TROP2 regulatory signaling; Calcium regulation in cardiac cells; Type II interferon signaling; T-cell receptor signaling pathway"	"CLEC7A (Dectin-1) signaling; KEAP1-NFE2L2 pathway; Neutrophil degranulation; Interferon gamma signaling; Role of phospholipids in phagocytosis; G alpha (z) signalling events; SHC1 events in ERBB2 signaling; HuR (ELAVL1) binds and stabilizes mRNA; VEGFR2 mediated cell proliferation; DAG and IP3 signaling; Effects of PIP2 hydrolysis; RHO GTPases Activate NADPH Oxidases; Calmodulin induced events; Apoptotic cleavage of cellular proteins"	"47"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30038"	"Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ALDH4A1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"563"	"61.7"	"8.07"	"315.84"	"2.72"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00171"	"8659"	"ENSG00000159423"	"ALDH4A1"	"A8K1Q7; B4DGE4; D2D4A3; hsa:8659; P30038; Q16882; Q53HU4; Q5JNV6; Q8IZ38; Q96IF0; Q9UDI6"	"22q11.2 copy number variation syndrome; p53 transcriptional gene network"	"Glyoxylate metabolism and glycine degradation; Proline catabolism"	"4"	"0"	"25.3"	"20.3"	"30.1"	"34.5"	"22.8"	"23.7"	"71.5"	"81.8"	"120.8"	"452.4"	"613.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08195"	"4F2 cell-surface antigen heavy chain OS=Homo sapiens OX=9606 GN=SLC3A2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"2"	"1"	"630"	"68.0"	"5.01"	"507.02"	"2.71"	"1"	"1"	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle;other cell component"	"transporter activity;nucleic acid binding activity"	"Pf00128, Pf16028"	"6520"	"ENSG00000168003"	"SLC3A2"	"hsa:6520; J3KPF3; P08195; Q13543"	"mRNA, protein, and metabolite inducation pathway by cyclosporin A; Ferroptosis; Proximal tubule transport; Pleural mesothelioma"	"Tryptophan catabolism; Basigin interactions; Amino acid transport across the plasma membrane; Defective SLC7A7 causes lysinuric protein intolerance (LPI)"	"8"	"0"	"11.0"	"11.2"	"10.7"	"11.2"	"7.0"	"9.0"	"18.3"	"18.8"	"26.9"	"62.6"	"94.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DV4"	"39S ribosomal protein L38, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL38 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"380"	"44.6"	"7.53"	"309.45"	"2.71"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	""	"Pf01161"	"64978"	"ENSG00000204316"	"MRPL38"	"B3KN96; hsa:64978; Q96DV4; Q96Q66; Q9P0B9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"88.9"	"72.2"	"105.2"	"125.0"	"83.1"	"63.7"	"106.6"	"120.5"	"124.4"	"348.2"	"635.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14757"	"Serine/threonine-protein kinase Chk1 OS=Homo sapiens OX=9606 GN=CHEK1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"476"	"54.4"	"8.25"	"391.87"	"2.71"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"1111"	"ENSG00000149554"	"CHEK1"	"A8K934; B4DDD0; B4DSK3; B5BTY6; F5H7S4; H2BI51; hsa:1111; O14757"	"miRNA regulation of DNA damage response; Cell cycle; Retinoblastoma gene in cancer; ATR signaling; ATM signaling in development and disease ; DNA repair pathways, full network; TROP2 regulatory signaling; DNA damage response"	"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Transcriptional Regulation by E2F6; Signaling by SCF-KIT; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex"	"18"	"0"	"36.5"	"40.7"	"39.3"	"55.6"	"38.4"	"45.2"	"64.6"	"71.9"	"95.0"	"214.8"	"303.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q71RC2"	"La-related protein 4 OS=Homo sapiens OX=9606 GN=LARP4 PE=1 SV=3"	"0.000"	""	"3"	"2"	"3"	"2"	"724"	"80.5"	"6.61"	"931.18"	"2.70"	"2"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;other cell component"	"nucleic acid binding activity"	"Pf05383"	"113251"	"ENSG00000161813"	"LARP4"	"A8K6T1; E9PDG5; G3XAA8; G5E976; hsa:113251; Q5CZ97; Q6ZV14; Q71RC2; Q96NF9"	""	""	"0"	"0"	"98.8"	"87.5"	"110.7"	"133.1"	"94.0"	"82.7"	"124.8"	"139.5"	"154.6"	"196.5"	"230.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXI1"	"Mitochondrial Rho GTPase 2 OS=Homo sapiens OX=9606 GN=RHOT2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"618"	"68.1"	"5.86"	"283.87"	"2.70"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00071, Pf08355, Pf08356"	"89941"	"ENSG00000140983"	"RHOT2"	"A2IDC2; hsa:89941; Q8IXI1; Q8NF53; Q96C13; Q96S17; Q9BT60; Q9H7M8"	""	"RHOT2 GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IWA0"	"WD repeat-containing protein 75 OS=Homo sapiens OX=9606 GN=WDR75 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"830"	"94.4"	"5.96"	""	"2.70"	""	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf00400"	"84128"	"ENSG00000115368"	"WDR75"	"hsa:84128; Q8IWA0; Q96J10; Q9H8U8; Q9H9U5; Q9H9V8; Q9UIX2"	""	"rRNA modification in the nucleus and cytosol; Major pathway of rRNA processing in the nucleolus and cytosol"	"2"	"0"	"31.1"	"18.5"	"40.1"	"37.2"	"35.1"	"33.4"	"38.9"	"46.9"	"59.7"	"135.0"	"167.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95363"	"Phenylalanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=FARS2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"451"	"52.3"	"7.46"	"293.31"	"2.69"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01409, Pf03147"	"10667"	"ENSG00000145982"	"FARS2"	"B2R664; hsa:10667; O95363; Q53F66; Q5TCS3; Q6FG29; Q9NPY7; Q9P062"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"7.2"	"6.6"	"3.4"	"5.8"	"5.7"	"5.5"	"10.6"	"10.3"	"12.9"	"36.8"	"46.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P51812"	"Ribosomal protein S6 kinase alpha-3 OS=Homo sapiens OX=9606 GN=RPS6KA3 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"740"	"83.7"	"6.89"	""	"2.69"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;kinase activity;other molecular function"	"Pf00069, Pf00433"	"6197"	"ENSG00000177189"	"RPS6KA3"	"B2R9V4; hsa:6197; P51812; Q4VAP3; Q59H26; Q5JPK8; Q7Z3Z7"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Kit receptor signaling pathway; MAPK signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Thermogenesis; EGF/EGFR signaling pathway; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; A network map of Macrophage-stimulating protein (MSP) signaling"	"Senescence-Associated Secretory Phenotype (SASP); Recycling pathway of L1; RSK activation; ERK/MAPK targets; CREB phosphorylation; Gastrin-CREB signalling pathway via PKC and MAPK"	"18"	"0"	"0.0"	"3.3"	"0.0"	"2.4"	"0.0"	"0.0"	"4.9"	"2.9"	"6.4"	"40.5"	"55.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P85037"	"Forkhead box protein K1 OS=Homo sapiens OX=9606 GN=FOXK1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"733"	"75.4"	"9.32"	"308.79"	"2.68"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00250, Pf00498"	"221937"	"ENSG00000164916"	"FOXK1"	"hsa:221937; P85037"	""	"UCH proteinases"	"1"	"0"	"11.5"	"6.8"	"9.3"	"15.3"	"9.0"	"3.9"	"18.5"	"19.1"	"25.6"	"51.6"	"103.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92552"	"28S ribosomal protein S27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS27 PE=1 SV=3"	"0.000"	""	"5"	"2"	"3"	"2"	"414"	"47.6"	"6.18"	"751.53"	"2.68"	"2"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"other membranes;mitochondrion;translational apparatus;nucleus;other cell component"	"translation activity;nucleic acid binding activity"	"Pf10037"	"23107"	"ENSG00000113048"	"MRPS27"	"B4DRT2; hsa:23107; Q6P1S1; Q92552"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"69.0"	"64.5"	"69.8"	"91.7"	"66.7"	"61.7"	"127.7"	"137.6"	"175.4"	"425.1"	"629.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TD10"	"Mirror-image polydactyly gene 1 protein OS=Homo sapiens OX=9606 GN=MIPOL1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"442"	"51.5"	"5.72"	"285.39"	"2.68"	"1"	"1"	""	"nucleus"	"other molecular function"	""	"145282"	"ENSG00000151338"	"MIPOL1"	"D3DSA4; hsa:145282; Q7Z3J0; Q8IV14; Q8TD10"	""	""	"0"	"0"	"89.8"	"62.3"	"84.7"	"97.5"	"74.5"	"69.9"	"120.2"	"112.5"	"136.3"	"343.3"	"489.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BU76"	"Multiple myeloma tumor-associated protein 2 OS=Homo sapiens OX=9606 GN=MMTAG2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"263"	"29.4"	"10.02"	"266.40"	"2.67"	"1"	"1"	""	"non-structural extracellular;other cell component"	""	"Pf10159"	"79169"	"ENSG00000143793"	"MMTAG2"	"hsa:79169; Q6P5Y0; Q6ZTZ6; Q6ZWA6; Q8IZH3; Q9BU76"	""	"Neutrophil degranulation"	"1"	"0"	"68.1"	"58.9"	"74.4"	"87.0"	"64.0"	"53.2"	"82.8"	"89.7"	"108.8"	"158.2"	"199.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GT1"	"Kelch-like protein 22 OS=Homo sapiens OX=9606 GN=KLHL22 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"634"	"71.6"	"5.49"	"329.71"	"2.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00651, Pf01344, Pf07707, Pf13415, Pf13964"	"84861"	"ENSG00000099910"	"KLHL22"	"A8K3Q4; A8MTV3; B7Z2G1; D3DX30; hsa:84861; Q53GT1; Q96B68; Q96KC6"	"22q11.2 copy number variation syndrome"	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3V6T2"	"Girdin OS=Homo sapiens OX=9606 GN=CCDC88A PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1871"	"215.9"	"6.21"	"299.52"	"2.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf19047"	"55704"	"ENSG00000115355"	"CCDC88A"	"A1IGE7; B7ZM78; C9JG83; hsa:55704; Q3V6T2; Q53SF1; Q581G3; Q5HYD0; Q7Z339; Q7Z3C5"	"Mesodermal commitment pathway"	"RND3 GTPase cycle; RND1 GTPase cycle"	"3"	"0"	"15.9"	"11.8"	"11.8"	"12.7"	"8.6"	"9.3"	"16.3"	"16.5"	"20.3"	"38.0"	"52.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15054"	"DNA polymerase delta subunit 3 OS=Homo sapiens OX=9606 GN=POLD3 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"466"	"51.4"	"9.35"	"296.45"	"2.67"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf09507"	"10714"	"ENSG00000077514"	"POLD3"	"B7ZAI6; hsa:10714; Q15054; Q32MZ9; Q32N00"	"Homologous recombination; Retinoblastoma gene in cancer; Pyrimidine metabolism; DNA replication; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching; Removal of the Flap Intermediate; Gap-filling DNA repair synthesis and ligation in GG-NER; Removal of the Flap Intermediate from the C-strand; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"26"	"0"	"14.7"	"15.0"	"18.0"	"15.2"	"14.2"	"14.7"	"27.3"	"29.9"	"35.3"	"88.3"	"121.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXQ5"	"Kelch-like protein 7 OS=Homo sapiens OX=9606 GN=KLHL7 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"586"	"65.9"	"6.48"	"286.62"	"2.67"	"1"	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00651, Pf01344, Pf07707"	"55975"	"ENSG00000122550"	"KLHL7"	"A4D144; B7Z5I9; G5E9G3; hsa:55975; Q7Z765; Q8IXQ5; Q96MV2; Q9BQF8; Q9UDQ9"	""	""	"0"	"0"	"15.8"	"11.3"	"22.5"	"28.7"	"13.7"	"17.5"	"40.6"	"38.4"	"57.7"	"258.2"	"549.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06609"	"DNA repair protein RAD51 homolog 1 OS=Homo sapiens OX=9606 GN=RAD51 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"339"	"36.9"	"5.60"	"281.11"	"2.67"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08423, Pf14520"	"5888"	"ENSG00000051180"	"RAD51"	"B0FXP0; B2R8T6; hsa:5888; Q06609; Q6FHX9; Q6ZNA8; Q9BV60"	"miRNA regulation of DNA damage response; Homologous recombination; ATM signaling pathway; RAC1/PAK1/p38/MMP2 pathway; Ovarian infertility; Breast cancer pathway; Pancreatic adenocarcinoma pathway; DNA repair pathways, full network; Primary ovarian insufficiency; DNA damage response"	"Resolution of D-loop Structures through Holliday Junction Intermediates; Transcriptional Regulation by E2F6; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51"	"23"	"0"	"3.4"	"5.3"	"2.8"	"6.8"	"4.3"	"2.1"	"8.8"	"4.7"	"11.0"	"36.5"	"40.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96CS3"	"FAS-associated factor 2 OS=Homo sapiens OX=9606 GN=FAF2 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"445"	"52.6"	"5.62"	"253.06"	"2.67"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport"	"non-structural extracellular;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00789, Pf14555"	"23197"	"ENSG00000113194"	"FAF2"	"hsa:23197; O94963; Q8IUF2; Q96CS3; Q9BRP2; Q9BVM7"	"5q35 copy number variation"	"Neutrophil degranulation; RHOA GTPase cycle"	"3"	"0"	"49.0"	"36.5"	"67.6"	"94.9"	"40.7"	"38.7"	"119.9"	"116.1"	"169.9"	"669.2"	"1088.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P26885"	"Peptidyl-prolyl cis-trans isomerase FKBP2 OS=Homo sapiens OX=9606 GN=FKBP2 PE=1 SV=2"	"0.000"	""	"13"	"2"	"3"	"2"	"142"	"15.6"	"9.13"	"637.12"	"2.66"	"2"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00254"	"2286"	"ENSG00000173486"	"FKBP2"	"hsa:2286; P26885; Q5BJH9; Q9BTS7"	"Complement system"	""	"1"	"0"	"122.4"	"108.6"	"140.8"	"169.0"	"103.2"	"104.3"	"338.3"	"347.5"	"567.6"	"1625.5"	"1789.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P82909"	"28S ribosomal protein S36, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS36 PE=1 SV=2"	"0.000"	""	"12"	"1"	"2"	"1"	"103"	"11.5"	"9.99"	"454.44"	"2.66"	"1"	"1"	"other metabolic processes"	"other membranes;mitochondrion"	""	""	"92259"	"ENSG00000134056; ENSG00000278461"	"MRPS36"	"hsa:92259; P82909; Q9H2H4"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"52.8"	"45.4"	"60.0"	"66.8"	"50.3"	"49.5"	"79.5"	"87.3"	"131.6"	"250.3"	"303.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZL9"	"Methionine adenosyltransferase 2 subunit beta OS=Homo sapiens OX=9606 GN=MAT2B PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"334"	"37.5"	"7.36"	"436.32"	"2.66"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf04321"	"27430"	"ENSG00000038274"	"MAT2B"	"B2R5Y6; hsa:27430; Q1WAI7; Q27J92; Q3LIE8; Q567T7; Q6NYC7; Q9BS89; Q9H3E1; Q9NZL9; Q9UJ54"	"Trans-sulfuration pathway; One-carbon metabolism; Trans-sulfuration, one-carbon metabolism and related pathways; Methionine de novo and salvage pathway; Methylation pathways"	"Ub-specific processing proteases; Methylation"	"7"	"0"	"41.0"	"50.5"	"52.3"	"73.8"	"38.9"	"34.0"	"71.8"	"78.8"	"87.1"	"244.7"	"385.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H0R6"	"Glutamyl-tRNA(Gln) amidotransferase subunit A, mitochondrial OS=Homo sapiens OX=9606 GN=QRSL1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"528"	"57.4"	"5.68"	"405.74"	"2.65"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf01425"	"55278"	"ENSG00000130348"	"QRSL1"	"hsa:55278; Q5VWJ4; Q9H0R6; Q9HA60; Q9NV19"	""	""	"0"	"0"	"6.5"	"5.5"	"10.1"	"10.5"	"8.8"	"9.7"	"17.6"	"15.8"	"20.7"	"36.0"	"50.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P23511"	"Nuclear transcription factor Y subunit alpha OS=Homo sapiens OX=9606 GN=NFYA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"347"	"36.9"	"8.94"	"359.12"	"2.65"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02045"	"4800"	"ENSG00000001167"	"NFYA"	"hsa:4800; P23511; Q8IXU0"	"Sterol regulatory element-binding proteins (SREBP) signaling; Wnt signaling pathway and pluripotency; Sudden infant death syndrome (SIDS) susceptibility pathways"	"PPARA activates gene expression; Activation of gene expression by SREBF (SREBP); FOXO-mediated transcription of cell death genes; ATF4 activates genes in response to endoplasmic reticulum  stress; ATF6 (ATF6-alpha) activates chaperone genes"	"8"	"0"	"191.1"	"176.2"	"180.6"	"201.2"	"149.3"	"170.9"	"295.5"	"307.4"	"433.1"	"794.8"	"559.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P265"	"Disco-interacting protein 2 homolog B OS=Homo sapiens OX=9606 GN=DIP2B PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1576"	"171.4"	"8.09"	""	"2.65"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity"	"Pf00501, Pf06464"	"57609"	"ENSG00000066084"	"DIP2B"	"hsa:57609; Q6B011; Q8N1L5; Q8NB38; Q9P265"	""	""	"0"	"0"	"7.6"	"5.2"	"9.0"	"12.9"	"5.3"	"8.5"	"16.7"	"12.2"	"23.6"	"49.4"	"71.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P83111"	"Serine beta-lactamase-like protein LACTB, mitochondrial OS=Homo sapiens OX=9606 GN=LACTB PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"547"	"60.7"	"8.53"	""	"2.65"	""	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00144"	"114294"	"ENSG00000103642"	"LACTB"	"hsa:114294; P83096; P83111"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P46459"	"Vesicle-fusing ATPase OS=Homo sapiens OX=9606 GN=NSF PE=1 SV=3"	"0.001"	""	"2"	"1"	"2"	"1"	"744"	"82.5"	"6.95"	"232.37"	"2.65"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00004, Pf02359, Pf02933, Pf17862"	"4905"	"ENSG00000073969; ENSG00000276262; ENSG00000278174"	"NSF"	"A8K2D9; B4DFA2; hsa:4905; P46459; Q8N6D7; Q9UKZ2"	"Synaptic vesicle pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway"	"COPII-mediated vesicle transport; COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Intra-Golgi traffic; Retrograde transport at the Trans-Golgi-Network; Trafficking of GluR2-containing AMPA receptors"	"8"	"0"	"3.3"	"2.1"	"6.5"	"6.9"	"1.7"	"0.0"	"6.3"	"5.6"	"8.3"	"27.6"	"52.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P30046"	"D-dopachrome decarboxylase OS=Homo sapiens OX=9606 GN=DDT PE=1 SV=3"	""	""	"9"	"1"	"1"	"1"	"118"	"12.7"	"7.30"	""	"2.64"	""	"1"	"other metabolic processes;other biological processes"	"non-structural extracellular;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf01187"	"1652"	"ENSG00000099977; ENSG00000275003"	"DDT"	"B7Z522; hsa:1652; O00774; O60787; P30046; Q13534"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13561"	"Dynactin subunit 2 OS=Homo sapiens OX=9606 GN=DCTN2 PE=1 SV=4"	"0.000"	""	"2"	"1"	"2"	"1"	"401"	"44.2"	"5.21"	"308.65"	"2.64"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf04912"	"10540"	"ENSG00000175203"	"DCTN2"	"B2RBK5; hsa:10540; Q13561; Q86YN2; Q9BW17"	""	"MHC class II antigen presentation; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; Recruitment of NuMA to mitotic centrosomes; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"11"	"0"	"49.4"	"50.3"	"58.5"	"101.9"	"52.7"	"43.7"	"111.4"	"125.7"	"202.1"	"772.4"	"1476.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P18206"	"Vinculin OS=Homo sapiens OX=9606 GN=VCL PE=1 SV=4"	"0.001"	""	"1"	"1"	"2"	"1"	"1134"	"123.7"	"5.66"	"247.39"	"2.64"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01044"	"7414"	"ENSG00000035403"	"VCL"	"hsa:7414; P18206; Q16450; Q5SWX2; Q7Z3B8; Q8IXU7"	"Integrin-mediated cell adhesion; Primary focal segmental glomerulosclerosis (FSGS); Focal adhesion; VEGFA-VEGFR2 signaling; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Melanoma; Regulation of actin cytoskeleton"	"Neutrophil degranulation; Platelet degranulation ; Signaling by BRAF and RAF1 fusions; Signaling by ALK fusions and activated point mutants; Smooth Muscle Contraction; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H582"	"Zinc finger protein 644 OS=Homo sapiens OX=9606 GN=ZNF644 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1327"	"149.5"	"8.16"	"293.21"	"2.64"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	""	"84146"	"ENSG00000122482"	"ZNF644"	"A2RU71; hsa:84146; Q2TAM0; Q5TCC0; Q6BEP7; Q6P446; Q6PI06; Q7LG67; Q9H582; Q9ULJ9"	""	""	"0"	"0"	"32.5"	"34.4"	"30.4"	"51.6"	"37.6"	"33.4"	"40.0"	"41.4"	"49.9"	"62.1"	"59.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55198"	"Protein AF-17 OS=Homo sapiens OX=9606 GN=MLLT6 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1093"	"112.0"	"8.62"	"307.74"	"2.64"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"nucleus"	"other molecular function"	"Pf00628, Pf13832"	"4302"	"ENSG00000275023; ENSG00000275851"	"MLLT6"	"hsa:4302; P55198; Q59F28; Q96IU3; Q9H5F6; Q9UF49"	"17q12 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BV73"	"Centrosome-associated protein CEP250 OS=Homo sapiens OX=9606 GN=CEP250 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"2442"	"281.0"	"5.02"	""	"2.64"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf15035"	"11190"	"ENSG00000126001"	"CEP250"	"E1P5Q3; hsa:11190; O14812; O60588; Q9BV73; Q9H450"	"Mesodermal commitment pathway"	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6ZMY9"	"Zinc finger protein 517 OS=Homo sapiens OX=9606 GN=ZNF517 PE=2 SV=2"	""	""	"4"	"1"	"1"	"1"	"492"	"54.7"	"8.97"	""	"2.64"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf01352"	"340385"	"ENSG00000197363"	"ZNF517"	"hsa:340385; Q6ZMY9"	""	"Generic Transcription Pathway"	"1"	"0"	"18.1"	"36.3"	"23.1"	"23.7"	"22.2"	"21.9"	"36.3"	"36.9"	"54.3"	"101.5"	"154.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19838"	"Nuclear factor NF-kappa-B p105 subunit OS=Homo sapiens OX=9606 GN=NFKB1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"968"	"105.3"	"5.40"	"268.55"	"2.64"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"non-structural extracellular;cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00023, Pf00531, Pf00554, Pf16179"	"4790"	"ENSG00000109320"	"NFKB1"	"A8K5Y5; B3KVE8; hsa:4790; P19838; Q68D84; Q86V43; Q8N4X7; Q9NZC0"	"Osteopontin signaling; Selenium micronutrient network; Vitamin B12 metabolism; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Folate metabolism; IL-1 signaling pathway; RANKL/RANK signaling pathway; Leptin signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; Alzheimer's disease and miRNA effects; Neural crest differentiation; IL-17 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Quercetin and Nf-kB / AP-1 induced apoptosis; PDGF pathway; Apoptosis; T cell receptor and co-stimulatory signaling; Aryl hydrocarbon receptor pathway; Ebstein-Barr virus LMP1 signaling; Cardiac hypertrophic response; Apoptosis-related network due to altered Notch3 in ovarian cancer; IL1 and megakaryocytes in obesity; Myometrial relaxation and contraction pathways; Melatonin metabolism and effects; RAC1/PAK1/p38/MMP2 pathway; Initiation of transcription and translation elongation at the HIV-1 LTR; Photodynamic therapy-induced NF-kB survival signaling; NAD metabolism, sirtuins and aging; Hepatitis C and hepatocellular carcinoma; MAPK signaling pathway; Apoptosis modulation by HSP70; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; TLR4 signaling and tolerance; Toll-like receptor signaling related to MyD88; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Novel intracellular components of RIG-I-like receptor pathway; MYD88 distinct input-output pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Chemokine signaling pathway; Oxidative damage response; IL-4 signaling pathway; Prion disease pathway; NO/cGMP/PKG mediated neuroprotection; Oxidative stress response; Fibrin complement receptor 3 signaling pathway; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Pancreatic adenocarcinoma pathway; miRNA role in immune response in sepsis; ncRNAs involved in STAT3 signaling in hepatocellular carcinoma; Non-genomic actions of 1,25 dihydroxyvitamin D3; Ciliary landscape; Nonalcoholic fatty liver disease; Supression of HMGB1 mediated inflammation by THBD; Altered glycosylation of MUC1 in tumor microenvironment; Resistin as a regulator of inflammation; Vitamin D in inflammatory diseases; Signal transduction through IL1R; Interactions between immune cells and microRNAs in tumor microenvironment; Canonical NF-kB pathway; Cancer immunotherapy by PD-1 blockade; Measles virus infection; Cytosolic DNA-sensing pathway; Small cell lung cancer; Gastrin signaling pathway; Hepatitis B infection; Head and neck squamous cell carcinoma; Aspirin and miRNAs; IL-18 signaling pathway; Autosomal recessive osteopetrosis pathways; FGF23 signaling in hypophosphatemic rickets and related disorders; TGF-beta receptor signaling in skeletal dysplasias; Kisspeptin/kisspeptin receptor system in the ovary; Activation of NLRP3 inflammasome by SARS-CoV-2; Host-pathogen interaction of human coronaviruses - interferon induction; 16p11.2 proximal deletion syndrome; STING pathway in Kawasaki-like disease and COVID-19; RAS and bradykinin pathways in COVID-19; Mitochondrial immune response to SARS-CoV-2; SARS-CoV-2 innate immunity evasion and cell-specific immune response; Modulators of TCR signaling and T cell activation; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Prostaglandin signaling; Antiviral and anti-inflammatory effects of Nrf2 on SARS-CoV-2 pathway; Inclusion body myositis; Alzheimer's disease; Th17 cell differentiation pathway; Ulcerative colitis signaling; SARS-CoV-2 mitochondrial chronic oxidative stress and endothelial dysfunction; Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids; Inflammatory bowel disease signaling; Genetic causes of porto-sinusoidal vascular disease; TROP2 regulatory signaling; Autophagy in pancreatic ductal adenocarcinoma; A network map of Macrophage-stimulating protein (MSP) signaling; Disturbed pathways in Duchenne Muscular Dystrophy; TAR syndrome; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; 10q22q23 copy number variation; TGF-beta receptor signaling; Notch signaling pathway; T-cell receptor signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways; Estrogen signaling pathway; Toll-like receptor signaling pathway"	"Neutrophil degranulation; FCERI mediated NF-kB activation; Downstream TCR signaling; Transcriptional regulation of white adipocyte differentiation; Activation of NF-kappaB in B cells; HCMV Early Events; Senescence-Associated Secretory Phenotype (SASP); Transcriptional Regulation by VENTX; PKMTs methylate histone lysines; RIP-mediated NFkB activation via ZBP1; NF-kB is activated and signals survival; TAK1-dependent IKK and NF-kappa-B activation  ; IkBA variant leads to EDA-ID; MAP3K8 (TPL2)-dependent MAPK1/3 activation; TRAF6 mediated NF-kB activation; The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection; SARS-CoV-1 activates/modulates innate immune responses; CD209 (DC-SIGN) signaling; Interleukin-1 processing; CLEC7A/inflammasome pathway; Regulated proteolysis of p75NTR; DEx/H-box helicases activate type I IFN and inflammatory cytokines production"	"142"	"0"	"64.7"	"47.0"	"88.5"	"94.3"	"57.1"	"61.7"	"91.9"	"108.1"	"143.8"	"229.4"	"342.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13308"	"Inactive tyrosine-protein kinase 7 OS=Homo sapiens OX=9606 GN=PTK7 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1070"	"118.3"	"7.09"	""	"2.63"	""	"1"	"cell adhesion;cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"kinase activity;other molecular function"	"Pf07679, Pf07714, Pf13927"	"5754"	"ENSG00000112655"	"PTK7"	"A8K974; B7Z477; E9PFZ5; hsa:5754; Q13308; Q13417; Q5T650; Q6IQ54; Q8NFA5; Q8NFA6; Q8NFA7; Q8NFA8"	""	""	"0"	"0"	"0.0"	"3.6"	"2.9"	"0.0"	"0.0"	"2.7"	"5.5"	"5.3"	"15.2"	"47.6"	"98.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96ME1"	"F-box/LRR-repeat protein 18 OS=Homo sapiens OX=9606 GN=FBXL18 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"805"	"88.3"	"8.32"	""	"2.63"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75376"	"Nuclear receptor corepressor 1 OS=Homo sapiens OX=9606 GN=NCOR1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"2440"	"270.0"	"7.11"	""	"2.62"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00249, Pf15784"	"9611"	"ENSG00000141027"	"NCOR1"	"B3DLF8; E9PGV6; hsa:9611; O75376; Q86YY0; Q9UPV5; Q9UQ18"	"Androgen receptor signaling pathway; Adipogenesis; Ovarian infertility; MECP2 and associated Rett syndrome; Pathways affected in adenoid cystic carcinoma; Rett syndrome causing genes; 22q11.2 copy number variation syndrome; Notch signaling pathway"	"PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; HCMV Early Events; Constitutive Signaling by NOTCH1 PEST Domain Mutants; Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants; Heme signaling; Transcriptional activation of mitochondrial biogenesis; HDACs deacetylate histones; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Nuclear Receptor transcription pathway; Cytoprotection by HMOX1; Nuclear signaling by ERBB4; Downregulation of SMAD2/3:SMAD4 transcriptional activity; NR1D1 (REV-ERBA) represses gene expression; NOTCH1 Intracellular Domain Regulates Transcription; Notch-HLH transcription pathway; Loss of MECP2 binding ability to the NCoR/SMRT complex; Regulation of MECP2 expression and activity; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis"	"30"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q04721"	"Neurogenic locus notch homolog protein 2 OS=Homo sapiens OX=9606 GN=NOTCH2 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2471"	"265.2"	"5.14"	"289.50"	"2.62"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00008, Pf00066, Pf06816, Pf07645, Pf07684, Pf12661, Pf12796"	"4853"	"ENSG00000134250"	"NOTCH2"	"hsa:4853; Q04721; Q5T3X7; Q99734; Q9H240"	"Neural crest differentiation; Notch signaling; Canonical and non-canonical Notch signaling; OSX and miRNAs in tooth development; Epithelial to mesenchymal transition in colorectal cancer; Breast cancer pathway; Head and neck squamous cell carcinoma; Osteoblast differentiation and related diseases; Genes controlling nephrogenesis; Primary ovarian insufficiency; Notch signaling pathway"	"NOTCH2 Activation and Transmission of Signal to the Nucleus; Pre-NOTCH Processing in Golgi; Pre-NOTCH Transcription and Translation; Notch-HLH transcription pathway; NOTCH2 intracellular domain regulates transcription; NOTCH4 Intracellular Domain Regulates Transcription; Pre-NOTCH Processing in the Endoplasmic Reticulum; Defective LFNG causes SCDO3"	"19"	"0"	"8.5"	"6.1"	"11.7"	"7.0"	"9.1"	"5.7"	"12.7"	"13.8"	"22.6"	"54.9"	"45.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O00469"	"Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 OS=Homo sapiens OX=9606 GN=PLOD2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"737"	"84.6"	"6.71"	""	"2.62"	""	"1"	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi"	"other molecular function"	"Pf03171"	"5352"	"ENSG00000152952"	"PLOD2"	"B3KWS3; hsa:5352; O00469; Q59ED2; Q8N170"	"Clear cell renal cell carcinoma pathways; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9P2F8"	"Signal-induced proliferation-associated 1-like protein 2 OS=Homo sapiens OX=9606 GN=SIPA1L2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1722"	"190.3"	"6.77"	""	"2.62"	""	"1"	"other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf00595, Pf02145, Pf11881"	"57568"	"ENSG00000116991"	"SIPA1L2"	"hsa:57568; Q2TV88; Q5VXR7; Q5VXR8; Q641Q4; Q8NA38; Q96DZ3; Q9H9F6; Q9P2F8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NG48"	"Protein Lines homolog 1 OS=Homo sapiens OX=9606 GN=LINS1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"757"	"85.8"	"6.52"	""	"2.62"	""	"1"	"other biological processes"	""	""	"Pf14694, Pf14695"	"55180"	"ENSG00000140471"	"LINS1"	"hsa:55180; Q8NG48; Q96FW2; Q9NVQ3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56381"	"ATP synthase subunit epsilon, mitochondrial OS=Homo sapiens OX=9606 GN=ATP5F1E PE=1 SV=2"	"0.000"	""	"14"	"1"	"2"	"1"	"51"	"5.8"	"9.92"	"268.52"	"2.62"	"1"	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04627"	"514"	"ENSG00000124172"	"ATP5F1E"	"B2RDD0; E1P5H6; hsa:514; P56381; Q53XU6"	"Electron transport chain: OXPHOS system in mitochondria; 7q11.23 copy number variation syndrome; Oxidative phosphorylation"	"Cristae formation; Formation of ATP by chemiosmotic coupling"	"5"	"0"	"105.3"	"136.8"	"128.6"	"133.6"	"97.5"	"73.6"	"201.8"	"219.7"	"240.6"	"499.6"	"706.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVD3"	"E3 ubiquitin-protein ligase RNF138 OS=Homo sapiens OX=9606 GN=RNF138 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"245"	"28.2"	"6.93"	"305.67"	"2.61"	"1"	"1"	"cell-cell signaling;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05605, Pf13923, Pf18574"	"51444"	"ENSG00000134758"	"RNF138"	"B2RE17; hsa:51444; Q8WVD3; Q9H8K2; Q9UF87; Q9UKI6"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"91.0"	"103.3"	"106.1"	"120.1"	"105.4"	"79.3"	"255.1"	"298.4"	"413.8"	"482.2"	"429.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y5V0"	"Zinc finger protein 706 OS=Homo sapiens OX=9606 GN=ZNF706 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"76"	"8.5"	"10.01"	""	"2.61"	""	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf04419, Pf12874"	"51123"	"ENSG00000120963"	"ZNF706"	"A8K362; hsa:51123; Q9Y5V0"	""	"Generic Transcription Pathway"	"1"	"0"	"97.8"	"139.5"	"101.5"	"106.5"	"88.4"	"61.8"	"144.5"	"168.8"	"192.3"	"175.4"	"102.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEY1"	"Neuron navigator 1 OS=Homo sapiens OX=9606 GN=NAV1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1877"	"202.3"	"8.07"	"259.61"	"2.60"	"1"	"1"	"cell organization and biogenesis;developmental processes"	"cytoskeleton;other cell component"	""	""	"89796"	"ENSG00000134369"	"NAV1"	"A8MS88; hsa:89796; Q5SVH1; Q5SVH2; Q5SVH3; Q5SVH7; Q5VUY9; Q8IVL2; Q8NEY1; Q96II1; Q9H7V9; Q9H9S9; Q9H9T5; Q9UGI1; Q9ULK7; Q9ULR9"	""	""	"0"	"0"	"13.7"	"11.1"	"10.5"	"14.3"	"8.0"	"9.7"	"14.6"	"15.0"	"19.9"	"32.3"	"40.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28702"	"Retinoic acid receptor RXR-beta OS=Homo sapiens OX=9606 GN=RXRB PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"533"	"56.9"	"8.18"	"257.71"	"2.60"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00104, Pf00105"	"6257"	"ENSG00000204231; ENSG00000206289; ENSG00000227322; ENSG00000228333; ENSG00000231321; ENSG00000235712"	"RXRB"	"hsa:6257; P28702; P28703; Q59G65; Q5JP92; Q5STQ1"	"Vitamin D metabolism; Nuclear receptors; PPAR signaling pathway; Non-small cell lung cancer; Non-genomic actions of 1,25 dihydroxyvitamin D3; Small cell lung cancer; IL-18 signaling pathway; Vitamin A1 and A5/X pathways; Vitamin A and carotenoid metabolism"	"PPARA activates gene expression; Nuclear Receptor transcription pathway; NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux; NR1H2 & NR1H3 regulate gene expression to control bile acid homeostasis; Signaling by Retinoic Acid; NR1H2 & NR1H3 regulate gene expression linked to lipogenesis; NR1H2 & NR1H3 regulate gene expression linked to triglyceride lipolysis in adipose; NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake ; NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis"	"18"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPW5"	"Cytosolic carboxypeptidase 1 OS=Homo sapiens OX=9606 GN=AGTPBP1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1226"	"138.4"	"6.15"	"261.63"	"2.59"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00246, Pf18027"	"23287"	"ENSG00000135049"	"AGTPBP1"	"B4DIT6; B4DRZ8; hsa:23287; Q5VV80; Q63HM7; Q658P5; Q6P9D6; Q9H8U6; Q9H9W8; Q9NVK1; Q9UPW5"	""	"Carboxyterminal post-translational modifications of tubulin"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NR33"	"DNA polymerase epsilon subunit 4 OS=Homo sapiens OX=9606 GN=POLE4 PE=1 SV=2"	"0.000"	""	"9"	"1"	"2"	"1"	"117"	"12.2"	"4.92"	"310.18"	"2.59"	"1"	"1"	"DNA metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00808"	"56655"	"ENSG00000115350"	"POLE4"	"hsa:56655; Q53TR2; Q9NR33"	"Pyrimidine metabolism; Base excision repair; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Activation of the pre-replicative complex; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Recognition of DNA damage by PCNA-containing replication complex; PCNA-Dependent Long Patch Base Excision Repair; Dual Incision in GG-NER; DNA replication initiation; Gap-filling DNA repair synthesis and ligation in GG-NER"	"16"	"0"	"11.8"	"8.9"	"17.3"	"27.8"	"8.8"	"5.9"	"16.9"	"24.4"	"29.0"	"68.0"	"83.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86T03"	"Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase OS=Homo sapiens OX=9606 GN=PIP4P1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"277"	"29.5"	"8.91"	"296.36"	"2.59"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf09788"	"90809"	"ENSG00000165782"	"PIP4P1"	"B2RA35; hsa:90809; Q86T03; Q86U09; Q8WUC0; Q9BU67; Q9NSU8"	""	"PI5P Regulates TP53 Acetylation; Synthesis of PIPs in the nucleus"	"2"	"0"	"8.5"	"5.8"	"13.9"	"5.4"	"6.5"	"4.2"	"14.3"	"10.3"	"18.3"	"45.0"	"76.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBB5"	"Methyl-CpG-binding domain protein 2 OS=Homo sapiens OX=9606 GN=MBD2 PE=1 SV=1"	"0.000"	""	"6"	"2"	"3"	"2"	"411"	"43.2"	"10.04"	"673.52"	"2.59"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01429, Pf14048, Pf16564"	"8932"	"ENSG00000134046"	"MBD2"	"hsa:8932; O95242; Q9UBB5; Q9UIS8"	"Effect of progerin on genes involved in Hutchinson-Gilford progeria syndrome"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Promoter Opening"	"3"	"0"	"8.1"	"9.3"	"12.8"	"15.1"	"12.6"	"14.8"	"21.8"	"18.7"	"19.8"	"58.2"	"75.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z478"	"ATP-dependent RNA helicase DHX29 OS=Homo sapiens OX=9606 GN=DHX29 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1369"	"155.1"	"8.09"	"248.22"	"2.59"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"54505"	"ENSG00000067248"	"DHX29"	"hsa:54505; O75549; Q63HN0; Q63HN3; Q7Z478; Q8IWW2; Q8N3A1; Q9UMH2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P15104"	"Glutamine synthetase OS=Homo sapiens OX=9606 GN=GLUL PE=1 SV=4"	""	""	"6"	"1"	"1"	"1"	"373"	"42.0"	"6.89"	""	"2.59"	""	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00120, Pf03951"	"2752"	"ENSG00000135821"	"GLUL"	"hsa:2752; P15104; Q499Y9; Q5T9Z1; Q7Z3W4; Q8IZ17"	"TNF-alpha signaling pathway; Amino acid metabolism"	"Glutamate and glutamine metabolism; Astrocytic Glutamate-Glutamine Uptake And Metabolism"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6IQ23"	"Pleckstrin homology domain-containing family A member 7 OS=Homo sapiens OX=9606 GN=PLEKHA7 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1121"	"127.1"	"9.35"	"293.28"	"2.59"	"1"	"1"	"cell adhesion;cell organization and biogenesis"	"other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00169"	"144100"	"ENSG00000166689"	"PLEKHA7"	"B4DK33; B4DWC3; hsa:144100; Q6IQ23; Q86VZ7"	""	""	"0"	"0"	"61.3"	"52.6"	"67.6"	"76.8"	"56.9"	"55.5"	"89.9"	"87.7"	"117.1"	"256.0"	"292.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWB7"	"Intraflagellar transport protein 57 homolog OS=Homo sapiens OX=9606 GN=IFT57 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"429"	"49.1"	"4.98"	"266.85"	"2.58"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;ER/Golgi;other cell component"	"nucleic acid binding activity"	"Pf10498"	"55081"	"ENSG00000114446"	"IFT57"	"hsa:55081; Q96DA9; Q9NWB7"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Intraflagellar transport; Hedgehog 'off' state"	"6"	"0"	"8.3"	"5.0"	"9.6"	"5.1"	"7.9"	"10.2"	"10.0"	"12.3"	"20.6"	"60.4"	"88.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16219"	"Short-chain specific acyl-CoA dehydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=ACADS PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"412"	"44.3"	"7.99"	"279.22"	"2.58"	"1"	"1"	"other metabolic processes"	"cytoskeleton;mitochondrion;nucleus"	"other molecular function"	"Pf00441, Pf02770, Pf02771"	"35"	"ENSG00000122971"	"ACADS"	"hsa:35; P16219; P78331"	"Fatty acid beta-oxidation; Mitochondrial long chain fatty acid beta-oxidation; IL-18 signaling pathway; Mitochondrial fatty acid oxidation disorders"	"Beta oxidation of hexanoyl-CoA to butanoyl-CoA; Beta oxidation of butanoyl-CoA to acetyl-CoA"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15067"	"Peroxisomal acyl-coenzyme A oxidase 1 OS=Homo sapiens OX=9606 GN=ACOX1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"660"	"74.4"	"8.16"	"312.57"	"2.58"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770, Pf14749"	"51"	"ENSG00000161533"	"ACOX1"	"A8K6X8; A8KAA0; B4DK61; F5GYQ8; hsa:51; Q12863; Q15067; Q15068; Q15101; Q16131; Q7Z3W5; Q9UD31"	"Estrogen receptor pathway; Nuclear receptors meta-pathway; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"TYSND1 cleaves peroxisomal proteins"	"8"	"0"	"111.9"	"99.6"	"135.2"	"111.3"	"99.8"	"102.3"	"182.1"	"183.4"	"279.9"	"722.9"	"1003.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z406"	"Myosin-14 OS=Homo sapiens OX=9606 GN=MYH14 PE=1 SV=2"	"0.000"	""	"1"	"2"	"2"	"1"	"1995"	"227.7"	"5.60"	"360.88"	"2.57"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"79784"	"ENSG00000105357"	"MYH14"	"B0I1S2; C3TTN4; hsa:79784; Q5CZ75; Q6XYE4; Q76B62; Q7Z406; Q8WV23; Q96I22; Q9BT27; Q9BW35; Q9H882"	""	"RHO GTPases activate CIT; EPHA-mediated growth cone collapse; Sema4D induced cell migration and growth-cone collapse; RHO GTPases activate PKNs; RHO GTPases Activate ROCKs; RHO GTPases activate PAKs"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43791"	"Speckle-type POZ protein OS=Homo sapiens OX=9606 GN=SPOP PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"374"	"42.1"	"5.80"	"288.11"	"2.57"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00651, Pf00917"	"8405"	"ENSG00000121067"	"SPOP"	"B2R6S3; D3DTW7; hsa:8405; O43791; Q53HJ1"	"mRNA processing; Hedgehog signaling pathway"	"Hedgehog 'on' state"	"3"	"0"	"6.1"	"5.0"	"8.3"	"12.6"	"7.6"	"9.0"	"12.5"	"19.6"	"28.0"	"91.2"	"135.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6D9"	"Mitotic spindle assembly checkpoint protein MAD1 OS=Homo sapiens OX=9606 GN=MAD1L1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"3"	"2"	"718"	"83.0"	"5.92"	"592.07"	"2.57"	"2"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf05557"	"8379"	"ENSG00000002822"	"MAD1L1"	"B3KR41; hsa:8379; Q13312; Q75MI0; Q86UM4; Q9UNH0; Q9Y6D9"	"Cell cycle; Regulation of sister chromatid separation at the metaphase-anaphase transition; Pleural mesothelioma; CCL18 signaling pathway"	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"10"	"0"	"205.1"	"160.6"	"328.4"	"243.3"	"168.5"	"184.4"	"315.0"	"258.6"	"287.9"	"567.9"	"675.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWS0"	"PHD finger protein 6 OS=Homo sapiens OX=9606 GN=PHF6 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"365"	"41.3"	"8.68"	"243.27"	"2.56"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf13771"	"84295"	"ENSG00000156531"	"PHF6"	"A8K230; B4E0G4; D3DTG3; E9PC97; hsa:84295; Q5JRC7; Q5JRC8; Q8IWS0; Q96JK3; Q9BRU0"	"Mesodermal commitment pathway"	""	"1"	"0"	"58.5"	"50.6"	"63.6"	"95.8"	"58.9"	"85.8"	"163.6"	"151.2"	"287.2"	"580.6"	"501.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUM4"	"Programmed cell death 6-interacting protein OS=Homo sapiens OX=9606 GN=PDCD6IP PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"868"	"96.0"	"6.52"	"317.94"	"2.56"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"non-structural extracellular;plasma membrane;cytosol;cytoskeleton;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf03097, Pf13949"	"10015"	"ENSG00000170248"	"PDCD6IP"	"C5MQH7; E9PFU1; hsa:10015; Q6NUS1; Q8WUM4; Q9BX86; Q9NUN0; Q9P2H2; Q9UKL5"	"Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells"	"Budding and maturation of HIV virion; Regulation of necroptotic cell death; Uptake and function of anthrax toxins"	"5"	"0"	"0.0"	"0.0"	"8.3"	"10.0"	"1.6"	"4.1"	"7.7"	"8.6"	"13.5"	"28.3"	"70.0"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P16383"	"GC-rich sequence DNA-binding factor 2 OS=Homo sapiens OX=9606 GN=GCFC2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"781"	"89.3"	"5.99"	"369.14"	"2.56"	"1"	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf07842"	"6936"	"ENSG00000005436"	"GCFC2"	"A4UHQ8; A4UHQ9; hsa:6936; O95032; P16383; Q53TY0; Q6P2F2"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"59.8"	"63.1"	"66.8"	"80.4"	"59.8"	"59.7"	"86.9"	"95.3"	"104.6"	"299.7"	"471.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99856"	"AT-rich interactive domain-containing protein 3A OS=Homo sapiens OX=9606 GN=ARID3A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"593"	"62.9"	"4.91"	"306.11"	"2.56"	"1"	"1"	"other biological processes"	"other membranes;cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf01388"	"1820"	"ENSG00000116017"	"ARID3A"	"hsa:1820; Q5I858; Q6P9C6; Q8IZA7; Q8N4Z3; Q99856"	""	"TP53 Regulates Transcription of Genes Involved in G1 Cell Cycle Arrest"	"1"	"0"	"6.8"	"5.4"	"11.0"	"15.6"	"10.1"	"7.9"	"10.1"	"11.7"	"11.7"	"16.4"	"20.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93075"	"Putative deoxyribonuclease TATDN2 OS=Homo sapiens OX=9606 GN=TATDN2 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"761"	"85.0"	"7.39"	"349.31"	"2.56"	"1"	"1"	""	"nucleus"	"other molecular function"	"Pf01026"	"9797"	"ENSG00000157014"	"TATDN2"	"hsa:9797; Q3MIL9; Q5BKU0; Q93075"	""	"XBP1(S) activates chaperone genes"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A4D1P6"	"WD repeat-containing protein 91 OS=Homo sapiens OX=9606 GN=WDR91 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"747"	"83.3"	"6.58"	""	"2.55"	""	"1"	"transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle"	"enzyme regulator activity"	"Pf00400"	"29062"	"ENSG00000105875"	"WDR91"	"A4D1P6; A6NK54; C9JMI4; hsa:29062; Q6FI65; Q6MZQ1; Q6P4I1; Q96AE5; Q96G63; Q9H062; Q9H9B6; Q9NVG7; Q9NZY6"	""	"CDC42 GTPase cycle"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y3D3"	"28S ribosomal protein S16, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS16 PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"137"	"15.3"	"9.50"	""	"2.55"	""	"1"	"protein metabolism;other metabolic processes"	"other membranes;cytosol;mitochondrion;translational apparatus"	"other molecular function"	"Pf00886"	"51021"	"ENSG00000182180"	"MRPS16"	"B4E032; hsa:51021; Q96Q60; Q9Y3D3"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"9.1"	"11.7"	"16.0"	"11.5"	"11.9"	"15.1"	"12.7"	"17.8"	"20.5"	"30.5"	"36.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61011"	"Signal recognition particle 54 kDa protein OS=Homo sapiens OX=9606 GN=SRP54 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"504"	"55.7"	"8.75"	"250.26"	"2.55"	"1"	"1"	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"cytosol;ER/Golgi;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00448, Pf02881, Pf02978"	"6729"	"ENSG00000100883"	"SRP54"	"B2R759; B4DUW6; hsa:6729; P13624; P61011"	"VEGFA-VEGFR2 signaling; mRNA processing"	"SRP-dependent cotranslational protein targeting to membrane"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86VU5"	"Catechol O-methyltransferase domain-containing protein 1 OS=Homo sapiens OX=9606 GN=COMTD1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"262"	"28.8"	"8.38"	"295.95"	"2.55"	"1"	"1"	"other metabolic processes"	"other membranes"	"other molecular function"	"Pf01596"	"118881"	"ENSG00000165644"	"COMTD1"	"hsa:118881; Q86VU5; Q8TE79"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WZ82"	"Esterase OVCA2 OS=Homo sapiens OX=9606 GN=OVCA2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"227"	"24.4"	"6.89"	"275.61"	"2.55"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf03959"	"124641"	"ENSG00000262664"	"OVCA2"	"hsa:124641; Q86XN3; Q8IW87; Q8WZ82; Q9UCX9"	""	""	"0"	"0"	"25.7"	"25.3"	"37.7"	"43.2"	"28.8"	"31.7"	"71.5"	"74.0"	"112.9"	"489.1"	"705.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UGY1"	"Nucleolar protein 12 OS=Homo sapiens OX=9606 GN=NOL12 PE=1 SV=1"	""	""	"10"	"1"	"1"	"1"	"213"	"24.6"	"10.23"	""	"2.55"	""	"1"	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf09805"	"79159"	"ENSG00000273899"	"NOL12"	"hsa:79159; Q9UGY1"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	"30.7"	"27.2"	"38.7"	"41.6"	"36.0"	"33.8"	"45.8"	"50.1"	"58.0"	"105.6"	"138.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969V3"	"Nicalin OS=Homo sapiens OX=9606 GN=NCLN PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"563"	"62.9"	"6.89"	"324.46"	"2.54"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"translation activity"	"Pf04389"	"56926"	"ENSG00000125912"	"NCLN"	"D6W613; hsa:56926; O75252; Q6FI60; Q6ZMB7; Q8TAT7; Q969V3; Q96H48; Q96IS7; Q9BQH9; Q9BTX4; Q9NPP2"	""	""	"0"	"0"	"6.1"	"9.9"	"6.8"	"14.4"	"9.3"	"5.8"	"17.4"	"12.9"	"33.3"	"110.2"	"125.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96QZ7"	"Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 OS=Homo sapiens OX=9606 GN=MAGI1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1491"	"164.5"	"7.58"	"365.16"	"2.54"	"1"	"1"	"cell adhesion;cell organization and biogenesis;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00397, Pf00595, Pf00625, Pf16663, Pf16666"	"9223"	"ENSG00000151276; ENSG00000282956"	"MAGI1"	"A8K188; hsa:9223; O00309; O43863; O75085; Q96QZ7; Q96QZ8; Q96QZ9"	"Pathways affected in adenoid cystic carcinoma"	""	"1"	"0"	"46.9"	"44.9"	"57.7"	"66.2"	"42.9"	"44.2"	"64.0"	"67.6"	"86.3"	"227.6"	"257.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BX10"	"GTP-binding protein 2 OS=Homo sapiens OX=9606 GN=GTPBP2 PE=1 SV=1"	"0.000"	""	"3"	"2"	"3"	"2"	"602"	"65.7"	"8.05"	"618.01"	"2.54"	"2"	"1"	"protein metabolism;other metabolic processes"	"non-structural extracellular;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00009"	"54676"	"ENSG00000172432"	"GTPBP2"	"hsa:54676; Q5T7E8; Q8ND84; Q8TAH7; Q8WUA5; Q9BX10; Q9HCS9; Q9NRU4; Q9NX60"	"Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway"	"Platelet degranulation"	"2"	"0"	"41.6"	"33.2"	"35.6"	"47.9"	"32.7"	"32.3"	"62.8"	"55.3"	"81.9"	"133.0"	"147.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75689"	"Arf-GAP with dual PH domain-containing protein 1 OS=Homo sapiens OX=9606 GN=ADAP1 PE=1 SV=2"	"0.000"	""	"6"	"3"	"4"	"2"	"374"	"43.4"	"8.97"	"845.31"	"2.54"	"3"	"1"	"signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"11033"	"ENSG00000105963"	"ADAP1"	"A4D2Q2; B3KRZ4; B4DVA6; F6XZ68; H7C2Q4; hsa:11033; O75689"	""	"Nuclear signaling by ERBB4"	"1"	"1"	"133.5"	"99.3"	"141.4"	"161.3"	"156.7"	"222.3"	"783.7"	"834.9"	"1171.3"	"1243.6"	"1152.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPF8"	"Arf-GAP with dual PH domain-containing protein 2 OS=Homo sapiens OX=9606 GN=ADAP2 PE=1 SV=1"	"0.000"	""	"4"	"2"	"3"	"1"	"381"	"44.3"	"9.36"	"554.34"	"2.54"	"2"	"1"	"developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01412"	"55803"	"ENSG00000184060"	"ADAP2"	"hsa:55803; Q8N4Q6; Q96SD5; Q9NPF8"	"TYROBP causal network in microglia"	""	"1"	"0"	"35.2"	"43.0"	"64.5"	"46.9"	"37.6"	"39.5"	"154.8"	"189.9"	"197.2"	"117.4"	"127.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JC1"	"Vam6/Vps39-like protein OS=Homo sapiens OX=9606 GN=VPS39 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"886"	"101.7"	"6.99"	"356.99"	"2.53"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;other cytoplasmic organelle;other cell component"	""	"Pf00780, Pf10366, Pf10367"	"23339"	"ENSG00000166887"	"VPS39"	"hsa:23339; O94869; Q71SQ6; Q7Z3V3; Q96B93; Q96JC1; Q96RM0"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; Perturbations to host-cell autophagy, induced by SARS-CoV-2 proteins"	"SARS-CoV-2 modulates autophagy"	"4"	"0"	"2.4"	"2.7"	"4.7"	"7.3"	"2.2"	"4.3"	"8.1"	"9.5"	"9.6"	"25.5"	"42.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P19447"	"General transcription and DNA repair factor IIH helicase subunit XPB OS=Homo sapiens OX=9606 GN=ERCC3 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"782"	"89.2"	"7.23"	"259.49"	"2.53"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04851, Pf13625, Pf16203"	"2071"	"ENSG00000163161"	"ERCC3"	"hsa:2071; P19447; Q53QM0"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	"5.4"	"4.7"	"5.8"	"5.7"	"6.6"	"10.0"	"13.4"	"12.3"	"14.5"	"22.5"	"25.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IXK0"	"Polyhomeotic-like protein 2 OS=Homo sapiens OX=9606 GN=PHC2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"858"	"90.7"	"8.69"	"307.58"	"2.53"	"1"	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00536, Pf16616"	"1912"	"ENSG00000134686"	"PHC2"	"A1L4Q1; A8KA40; D3DPR2; hsa:1912; Q2TAL3; Q5T0C1; Q6NUJ6; Q6ZQR1; Q8IXK0; Q8N306; Q8TAG8; Q96BL4; Q9Y4Y7"	""	"Regulation of PTEN gene transcription; Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"8"	"0"	"94.9"	"97.8"	"102.5"	"98.5"	"89.1"	"98.2"	"110.9"	"112.8"	"130.3"	"256.4"	"274.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRY4"	"Rho GTPase-activating protein 35 OS=Homo sapiens OX=9606 GN=ARHGAP35 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1499"	"170.4"	"6.64"	"282.76"	"2.53"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00071, Pf00620, Pf01846, Pf16512, Pf19518"	"2909"	"ENSG00000160007"	"ARHGAP35"	"A7E2A4; hsa:2909; Q14452; Q9C0E1; Q9NRY4"	"Focal adhesion; Regulation of actin cytoskeleton"	"RND3 GTPase cycle; RHOC GTPase cycle; RHOA GTPase cycle; CDC42 GTPase cycle; RAC1 GTPase cycle; RHOB GTPase cycle; RND2 GTPase cycle; RHOQ GTPase cycle; RHOG GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; RHOJ GTPase cycle; RND1 GTPase cycle; Sema4D mediated inhibition of cell attachment and migration; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"18"	"0"	"0.0"	"0.0"	"0.0"	"3.6"	"0.0"	"0.0"	"5.6"	"8.6"	"13.8"	"50.0"	"64.4"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O95870"	"Phosphatidylserine lipase ABHD16A OS=Homo sapiens OX=9606 GN=ABHD16A PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"558"	"63.2"	"8.13"	""	"2.53"	""	"1"	"other metabolic processes"	"other membranes"	"other molecular function"	"Pf00561"	"7920"	"ENSG00000204427; ENSG00000206403; ENSG00000224552; ENSG00000230475; ENSG00000231488; ENSG00000235676; ENSG00000236063"	"ABHD16A"	"A2BEY3; B7Z4R6; hsa:7920; O95870; Q5SRR1; Q5SRR2; Q8WYH0; Q9NW33"	"IL-18 signaling pathway"	""	"1"	"0"	"139.9"	"53.7"	"137.5"	"129.8"	"118.2"	"134.7"	"131.8"	"119.6"	"118.2"	"127.6"	"267.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13416"	"Origin recognition complex subunit 2 OS=Homo sapiens OX=9606 GN=ORC2 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"2"	"577"	"65.9"	"6.51"	"571.63"	"2.53"	"2"	"1"	"DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04084"	"4999"	"ENSG00000115942"	"ORC2"	"hsa:4999; Q13204; Q13416; Q53TX5"	"Cell cycle; G1 to S cell cycle control; DNA replication"	"Orc1 removal from chromatin; Activation of ATR in response to replication stress; Activation of the pre-replicative complex; E2F-enabled inhibition of pre-replication complex formation; Assembly of the ORC complex at the origin of replication; CDC6 association with the ORC:origin complex"	"10"	"0"	"318.6"	"241.6"	"276.4"	"337.0"	"254.0"	"269.4"	"410.8"	"430.5"	"559.4"	"1493.0"	"2002.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75419"	"Cell division control protein 45 homolog OS=Homo sapiens OX=9606 GN=CDC45 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"566"	"65.5"	"5.53"	"301.44"	"2.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;signal transduction"	"cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf02724"	"8318"	"ENSG00000093009"	"CDC45"	"B4DDB4; B4DDU3; E9PDH7; hsa:8318; O60856; O75419; Q20WK8; Q6UW54; Q9UP68"	"Cell cycle; Retinoblastoma gene in cancer; G1 to S cell cycle control; 22q11.2 copy number variation syndrome; DNA replication"	"Activation of ATR in response to replication stress; Activation of the pre-replicative complex; Unwinding of DNA; G1/S-Specific Transcription"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O43823"	"A-kinase anchor protein 8 OS=Homo sapiens OX=9606 GN=AKAP8 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"692"	"76.1"	"5.15"	""	"2.52"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"mitochondrion;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf04988"	"10270"	"ENSG00000105127"	"AKAP8"	"hsa:10270; O43823"	"G protein signaling pathways"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UGL1"	"Lysine-specific demethylase 5B OS=Homo sapiens OX=9606 GN=KDM5B PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"1544"	"175.5"	"6.70"	""	"2.52"	""	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf01388, Pf02373, Pf02375, Pf02928, Pf08429"	"10765"	"ENSG00000117139"	"KDM5B"	"hsa:10765; O95811; Q15752; Q9UGL1; Q9Y3Q5"	"Rett syndrome causing genes"	"HDMs demethylate histones; TFAP2 (AP-2) family regulates transcription of cell cycle factors"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NHV4"	"Protein NEDD1 OS=Homo sapiens OX=9606 GN=NEDD1 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"660"	"71.9"	"7.97"	""	"2.52"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity"	"Pf00400"	"121441"	"ENSG00000139350"	"NEDD1"	"B0AZN0; B4E145; G3V3F1; hsa:121441; Q8NA30; Q8NHV4"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"38.8"	"16.4"	"76.2"	"86.4"	"43.3"	"58.1"	"95.0"	"68.7"	"119.0"	"289.4"	"551.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00257"	"E3 SUMO-protein ligase CBX4 OS=Homo sapiens OX=9606 GN=CBX4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"560"	"61.3"	"9.36"	"292.56"	"2.52"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00385, Pf17218"	"8535"	"ENSG00000141582"	"CBX4"	"B1PJR7; hsa:8535; O00257; Q6TPI8; Q96C04"	""	"SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Oxidative Stress Induced Senescence; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription"	"8"	"0"	"109.4"	"110.8"	"128.9"	"158.7"	"115.9"	"109.7"	"181.8"	"185.5"	"245.5"	"501.1"	"587.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BRT9"	"DNA replication complex GINS protein SLD5 OS=Homo sapiens OX=9606 GN=GINS4 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"223"	"26.0"	"4.98"	"273.41"	"2.52"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	""	"Pf05916, Pf16922"	"84296"	"ENSG00000147536"	"GINS4"	"B2R8H5; D3DSY0; hsa:84296; Q8N648; Q9BRT9"	""	"Unwinding of DNA"	"1"	"0"	"7.7"	"6.3"	"7.2"	"9.1"	"4.6"	"4.2"	"11.2"	"11.5"	"10.5"	"22.2"	"21.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IX90"	"Spindle and kinetochore-associated protein 3 OS=Homo sapiens OX=9606 GN=SKA3 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"412"	"46.3"	"5.11"	""	"2.51"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;cytoskeleton;other cell component"	""	""	"221150"	"ENSG00000165480"	"SKA3"	"A2A330; A2A331; B2RBY2; hsa:221150; Q5VZV5; Q86WR2; Q8IX90; Q8NBG1; Q96D22"	""	""	"0"	"0"	"14.7"	"10.3"	"12.1"	"16.2"	"10.3"	"8.8"	"14.0"	"19.1"	"19.0"	"38.0"	"45.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P16220"	"Cyclic AMP-responsive element-binding protein 1 OS=Homo sapiens OX=9606 GN=CREB1 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"341"	"36.7"	"5.57"	""	"2.51"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170, Pf02173"	"100351999; 100477711; 100586647; 100675162; 100974672; 101010524; 101356881; 101383024; 101608568; 101964691; 102141699; 102246867; 102428529; 102531048; 102748542; 103217717; 103744440; 104680220; 105468005; 105517357; 105549382; 105580103; 105864304; 106967098; 108540349; 109691946; 1385; 459901; 607922; 708717"	"ENSAMEG00000015152; ENSCAFG00000013510; ENSCAFG00030010510; ENSCAFG00040025786; ENSCAFG00845022020; ENSCANG00000030079; ENSCATG00000037133; ENSCCNG00000003127; ENSCSAG00000010111; ENSFCAG00000008220; ENSGGOG00000024394; ENSJJAG00000013846; ENSLAFG00000013257; ENSLCNG00005016477; ENSMFAG00000039629; ENSMICG00000009731; ENSMLEG00000033904; ENSMLUG00000016119; ENSMMMG00000014914; ENSMMUG00000022601; ENSMNEG00000030274; ENSNGAG00000018967; ENSNLEG00000007124; ENSOCUG00000005427; ENSPANG00000009083; ENSPLOG00000007090; ENSPPAG00000042817; ENSPPYG00000013115; ENSPTIG00000011848; ENSPTRG00000043959; ENSRBIG00000040701; ENSRFEG00010020193; ENSRROG00000035316; ENSSDAG00000020160; ENSSSCG00005034714; ENSSSCG00015008370; ENSSSCG00025020324; ENSSSCG00030035186; ENSSSCG00035079382; ENSSSCG00040036512; ENSSSCG00045023175; ENSSSCG00050037141; ENSSSCG00055008554; ENSSSCG00060058264; ENSSSCG00065052126; ENSSSCG00070020566; ENSSSUG00005001816; ENSSTOG00000016482; ENSSVLG00005003093; ENSTGEG00000004249; ENSUAMG00000018783; ENSUMAG00000022656; ENSUPAG00010007984; ENSVVUG00000011892"	"Creb1; CREB1; LOC101356881"	"A0A024R401; A0A096MS95; A0A0D9RCK8; A0A286ZWB0; A0A2I2YCF6; A0A2J8N5U5; A0A2J8WUF2; A0A2K5I9K2; A0A2K5MQP0; A0A2K5X536; A0A2K5X539; A0A2K5YUX5; A0A2K6BKD0; A0A2K6MDT5; A0A2K6Q2B5; A0A2R9CPF8; A0A2U3WAS2; A0A2U3XPQ5; A0A2Y9R2V7; A0A384BST9; A0A3Q7QRU5; A0A3Q7SQX8; A0A452RWS8; A0A4X1V0B9; A0A5E4AFY5; A0A5N4E668; A0A667HEB5; A0A671G6M8; A0A673T0V2; A0A6D2VSK7; A0A6D2WEQ2; A0A6G1BFF3; A0A6I9IA29; A0A6J1YUG6; A0A6J2CMJ0; A0A6J2LK21; A0A6P6GX89; A0A7J7WGC8; A0A7J7XTS6; A0A7J8FQY6; A0A811ZBK8; A0A8B7V7Z4; A0A8B8T0S6; A0A8C0N7M6; A0A8C5KHE0; A0A8C5V357; A0A8C6EUY0; A0A8C6RKM3; A0A8C8WVH7; A0A8C9JRV6; A0A8C9Q947; A0A8D2AN63; A0A8D2EE05; A0A8D2H908; A0A8I3S2U7; A0A8J8XE04; A0A8J8XJ71; A0A8M1M6Z7; aju:106967098; aml:100477711; cang:105517357; caty:105580103; ccan:109691946; cfa:607922; cfr:102508765; csab:103217717; D2H8G8; F7AUB4; G1PTV7; G1R662; G1SNW9; G3TAZ1; G7N8R8; H2P8F2; H2R2Y2; I3MRM5; lav:100675162; lww:102748542; M3W964; mcc:708717; mcf:102141699; mleu:105549382; mlf:102428529; mmur:105864304; myb:102246867; ngi:103744440; ocu:100351999; oro:101383024; pdic:114495167; ptr:459901; Q5U0J5; rbb:108540349; rro:104680220; S7N6N9; tmu:101356881; umr:103659802; vpc:102531048; vvp:112922611; zca:113919503"	"IL-2 signaling pathway; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control; Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Energy metabolism; miRNAs involved in DNA damage response; Folate-alcohol and cancer pathway hypotheses; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; B cell receptor signaling pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Adipogenesis; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; ATM signaling pathway; Myometrial relaxation and contraction pathways; VEGFA-VEGFR2 signaling; Mitochondrial gene expression; p38 MAPK signaling pathway; EGF/EGFR signaling pathway; G1 to S cell cycle control; Gastrin signaling pathway; CAMKK2 pathway; Galanin receptor pathway; Neuroinflammation and glutamatergic signaling; GDNF signaling; Interferon type I signaling pathways; T-cell receptor signaling pathway; Sudden infant death syndrome (SIDS) susceptibility pathways; DNA damage response; Estrogen signaling pathway; Serotonin HTR1 group and FOS pathway; Serotonin receptor 4/6/7 and NR3C signaling; EGFR1 signaling pathway; Adipogenesis; Androgen receptor signaling pathway; p38 MAPK signaling pathway; G1 to S cell cycle control"	"NCAM signaling for neurite out-growth; CREB phosphorylation; CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling; Gastrin-CREB signalling pathway via PKC and MAPK; NGF-stimulated transcription"	"49"	"0"	"45.2"	"30.0"	"52.4"	"61.5"	"47.0"	"28.7"	"80.4"	"73.1"	"117.6"	"300.9"	"389.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH03"	"Neuronal-specific septin-3 OS=Homo sapiens OX=9606 GN=SEPTIN3 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"358"	"40.7"	"7.20"	"327.03"	"2.51"	"1"	"1"	"cell cycle OR cell proliferation"	"cytoskeleton;other cell component"	"other molecular function"	"Pf00735"	"55964"	"ENSG00000100167"	"SEPTIN3"	"B1AHR0; hsa:55964; Q2NKJ7; Q59GF7; Q6IBZ6; Q8N3P3; Q9HD35; Q9UH03"	""	""	"0"	"0"	"29.5"	"21.4"	"36.9"	"35.5"	"30.4"	"36.9"	"66.9"	"70.7"	"111.0"	"205.8"	"268.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95625"	"Zinc finger and BTB domain-containing protein 11 OS=Homo sapiens OX=9606 GN=ZBTB11 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1053"	"119.3"	"8.66"	"284.57"	"2.51"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf00651, Pf13912, Pf17921"	"27107"	"ENSG00000066422"	"ZBTB11"	"hsa:27107; O95625; Q2NKP9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6WRX3"	"Protein zyg-11 homolog A OS=Homo sapiens OX=9606 GN=ZYG11A PE=2 SV=3"	""	""	"3"	"1"	"1"	"1"	"759"	"85.8"	"7.97"	""	"2.50"	""	"1"	""	"other cell component"	""	""	"440590"	"ENSG00000203995"	"ZYG11A"	"A6NCK5; hsa:440590; Q6WRX3"	""	""	"0"	"0"	"12.8"	"13.8"	"17.2"	"19.6"	"12.1"	"8.8"	"66.4"	"74.9"	"165.0"	"415.1"	"521.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H2D6"	"TRIO and F-actin-binding protein OS=Homo sapiens OX=9606 GN=TRIOBP PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"2365"	"261.2"	"8.48"	""	"2.50"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00169"	"11078"	"ENSG00000100106"	"TRIOBP"	"B1AHD4; B1AHD7; F2Z2W0; F8W6V6; hsa:11078; O94797; Q2PZW8; Q2Q3Z9; Q2Q400; Q5R3M6; Q96DW1; Q9BT77; Q9BTL7; Q9BY98; Q9H2D6; Q9Y3L4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35558"	"Phosphoenolpyruvate carboxykinase, cytosolic [GTP] OS=Homo sapiens OX=9606 GN=PCK1 PE=1 SV=3"	"0.001"	""	"4"	"2"	"2"	"1"	"622"	"69.2"	"6.14"	"232.17"	"2.50"	"1"	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;ER/Golgi;other cell component"	"kinase activity;other molecular function"	"Pf00821, Pf17297"	"5105"	"ENSG00000124253"	"PCK1"	"A8K437; B4DT64; hsa:5105; P35558; Q8TCA3; Q9UJD2"	"Adipogenesis; TCA cycle and deficiency of pyruvate dehydrogenase complex (PDHc); Estrogen receptor pathway; Nuclear receptors meta-pathway; Angiopoietin-like protein 8 regulatory pathway; Amino acid metabolism; PPAR signaling pathway; PI3K-Akt signaling pathway; Glycolysis and gluconeogenesis; Metabolic Epileptic Disorders"	"Gluconeogenesis; Transcriptional regulation of white adipocyte differentiation; FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes; Abacavir metabolism; NR1H2 & NR1H3 regulate gene expression linked to gluconeogenesis"	"15"	"0"	"70.2"	"32.8"	"92.7"	"82.2"	"80.3"	"74.7"	"73.4"	"62.0"	"63.0"	"84.9"	"80.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O60496"	"Docking protein 2 OS=Homo sapiens OX=9606 GN=DOK2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"412"	"45.4"	"6.02"	""	"2.50"	""	"1"	"signal transduction;other biological processes"	"cytosol;other cell component"	"signal transduction activity or receptor binding"	"Pf02174"	"9046"	"ENSG00000147443"	"DOK2"	"hsa:9046; O60496; Q8N5A4"	"RAC1/PAK1/p38/MMP2 pathway; IL-4 signaling pathway; EGF/EGFR signaling pathway"	"RET signaling; Tie2 Signaling"	"5"	"0"	"140.9"	"34.8"	"256.6"	"223.9"	"150.9"	"164.1"	"184.9"	"142.1"	"186.0"	"360.2"	"668.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P06746"	"DNA polymerase beta OS=Homo sapiens OX=9606 GN=POLB PE=1 SV=3"	"0.000"	""	"7"	"2"	"3"	"2"	"335"	"38.2"	"8.95"	"783.23"	"2.50"	"2"	"1"	"DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf10391, Pf14716, Pf14791, Pf14792"	"5423"	"ENSG00000070501"	"POLB"	"B2RC78; hsa:5423; P06746; Q3KP48; Q6FI34"	"Male infertility; Base excision repair; DNA repair pathways, full network"	"Ub-specific processing proteases; APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway; POLB-Dependent Long Patch Base Excision Repair; PCNA-Dependent Long Patch Base Excision Repair; Abasic sugar-phosphate removal via the single-nucleotide replacement pathway"	"10"	"0"	"48.2"	"47.7"	"56.1"	"93.0"	"36.2"	"41.9"	"156.6"	"181.9"	"333.9"	"444.3"	"351.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43674"	"NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 5, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFB5 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"189"	"21.7"	"9.63"	"275.30"	"2.50"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;transport"	"other membranes;mitochondrion;nucleus"	"transporter activity"	"Pf09781"	"4711"	"ENSG00000136521"	"NDUFB5"	"hsa:4711; O43674; Q561V6"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"4.9"	"0.0"	"3.3"	"5.0"	"4.0"	"0.0"	"5.0"	"7.2"	"13.3"	"40.4"	"56.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9C0I1"	"Myotubularin-related protein 12 OS=Homo sapiens OX=9606 GN=MTMR12 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"747"	"86.1"	"6.62"	""	"2.49"	""	"1"	"transport"	"cytosol;cytoskeleton;ER/Golgi;other cell component"	""	"Pf06602, Pf12578"	"54545"	"ENSG00000150712"	"MTMR12"	"hsa:54545; Q69YJ4; Q6PFW3; Q96QU2; Q9C0I1; Q9NX27"	""	"Synthesis of PIPs at the early endosome membrane"	"1"	"0"	"60.5"	"39.0"	"54.5"	"76.7"	"56.6"	"66.1"	"129.2"	"136.9"	"177.0"	"287.7"	"336.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96C90"	"Protein phosphatase 1 regulatory subunit 14B OS=Homo sapiens OX=9606 GN=PPP1R14B PE=1 SV=3"	""	""	"10"	"1"	"1"	"1"	"147"	"15.9"	"4.86"	""	"2.49"	""	"1"	"stress response;other biological processes"	"other cell component"	"enzyme regulator activity"	"Pf05361"	"26472"	"ENSG00000173457"	"PPP1R14B"	"hsa:26472; Q504S7; Q7KZD7; Q96C90"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99798"	"Aconitate hydratase, mitochondrial OS=Homo sapiens OX=9606 GN=ACO2 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"780"	"85.4"	"7.61"	"236.40"	"2.49"	"1"	"1"	"other metabolic processes;stress response;developmental processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf00330, Pf00694"	"50"	"ENSG00000100412"	"ACO2"	"hsa:50; O75809; Q5JZ41; Q6FHX0; Q8TAQ6; Q99798"	"Amino acid metabolism; Metabolic reprogramming in colon cancer; Fluoroacetic acid toxicity; TCA cycle (aka Krebs or citric acid cycle)"	"Citric acid cycle (TCA cycle); Mitochondrial protein import"	"6"	"0"	"9.9"	"2.9"	"17.1"	"13.7"	"9.6"	"10.2"	"20.4"	"16.2"	"19.6"	"66.8"	"113.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6IE37"	"Ovostatin homolog 1 OS=Homo sapiens OX=9606 GN=OVOS1 PE=2 SV=2"	""	""	"2"	"1"	"1"	"1"	"1185"	"134.4"	"5.29"	""	"2.49"	""	"1"	"other biological processes"	"non-structural extracellular"	"enzyme regulator activity"	"Pf00207, Pf07677, Pf07678, Pf07703, Pf17789, Pf17791"	""	""	"OVOS1"	"Q6IE37"	""	""	"0"	"0"	"15.2"	"26.9"	"22.1"	"20.6"	"18.2"	"20.0"	"78.2"	"85.1"	"165.9"	"261.1"	"342.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HB19"	"Pleckstrin homology domain-containing family A member 2 OS=Homo sapiens OX=9606 GN=PLEKHA2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"425"	"47.2"	"8.66"	"270.00"	"2.49"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"other molecular function"	"Pf00169"	"59339"	""	"PLEKHA2"	"hsa:59339; Q9HB19"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"2.3"	"0.0"	"5.2"	"3.7"	"1.8"	"6.9"	"11.8"	"11.6"	"19.7"	"43.9"	"50.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27448"	"MAP/microtubule affinity-regulating kinase 3 OS=Homo sapiens OX=9606 GN=MARK3 PE=1 SV=5"	"0.000"	""	"2"	"1"	"2"	"1"	"753"	"84.4"	"9.57"	"408.95"	"2.49"	"1"	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00627, Pf02149"	"4140"	"ENSG00000075413"	"MARK3"	"A0A0A0MQR8; A0A0A0MST9; A0A0A0MT23; hsa:4140; O60219; P27448; Q86TT8; Q8TB41; Q8WX83; Q96RG1; Q9UMY9; Q9UN34"	"Complement system in neuronal development and plasticity"	"Signaling by BRAF and RAF1 fusions; RAF activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants"	"10"	"0"	"5.5"	"5.5"	"2.7"	"7.1"	"7.0"	"3.1"	"9.0"	"13.4"	"15.8"	"28.0"	"33.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q00796"	"Sorbitol dehydrogenase OS=Homo sapiens OX=9606 GN=SORD PE=1 SV=4"	"0.000"	""	"3"	"1"	"2"	"1"	"357"	"38.3"	"7.97"	"282.10"	"2.48"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"non-structural extracellular;other membranes;cytosol;cytoskeleton;mitochondrion"	"other molecular function"	"Pf00107, Pf08240"	"6652"	"ENSG00000140263"	"SORD"	"B2R655; B7Z3A6; hsa:6652; J3JZZ5; Q00796; Q16682; Q9UMD6"	"Disorders of fructose metabolism; Polyol pathway"	"Formation of xylulose-5-phosphate; Fructose biosynthesis"	"4"	"0"	"4.8"	"4.8"	"6.5"	"10.4"	"4.4"	"7.0"	"8.0"	"9.0"	"10.6"	"23.4"	"42.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N5L8"	"Ribonuclease P protein subunit p25-like protein OS=Homo sapiens OX=9606 GN=RPP25L PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"163"	"17.6"	"10.30"	"303.99"	"2.48"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus;other cell component"	""	"Pf01918"	"138716"	"ENSG00000164967"	"RPP25L"	"D3DRM5; hsa:138716; Q8N5L8"	""	""	"0"	"0"	"91.2"	"39.2"	"88.6"	"102.4"	"77.5"	"76.3"	"94.9"	"88.5"	"101.4"	"155.9"	"232.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ04"	"Testis-specific Y-encoded-like protein 4 OS=Homo sapiens OX=9606 GN=TSPYL4 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"414"	"45.1"	"8.57"	"316.25"	"2.48"	"1"	"1"	"cell organization and biogenesis"	"nucleus;other cell component"	"other molecular function"	"Pf00956"	"23270"	"ENSG00000187189"	"TSPYL4"	"B4DYQ2; hsa:23270; O94828; Q96GW8; Q9UJ04"	""	""	"0"	"0"	"16.4"	"18.3"	"14.8"	"16.6"	"12.7"	"13.3"	"18.3"	"16.4"	"24.4"	"30.3"	"26.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60315"	"Zinc finger E-box-binding homeobox 2 OS=Homo sapiens OX=9606 GN=ZEB2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1214"	"136.4"	"6.32"	"356.28"	"2.48"	"1"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00096, Pf05605, Pf12874"	"9839"	"ENSG00000169554"	"ZEB2"	"A0JP09; B7Z2P2; F5H814; hsa:9839; O60315; Q9UED1"	"Mammary gland development pathway - Embryonic development (Stage 1 of 4); Epithelial to mesenchymal transition in colorectal cancer; TGF-beta receptor signaling in skeletal dysplasias; CCL18 signaling pathway; Extrafollicular and follicular B cell activation by SARS-CoV-2; A network map of Macrophage-stimulating protein (MSP) signaling; TGF-beta receptor signaling"	"Regulation of CDH11 gene transcription"	"8"	"0"	"6.5"	"3.0"	"2.9"	"8.8"	"3.7"	"3.1"	"7.6"	"10.6"	"12.5"	"27.4"	"39.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10619"	"Lysosomal protective protein OS=Homo sapiens OX=9606 GN=CTSA PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"480"	"54.4"	"6.61"	"306.06"	"2.48"	"1"	"1"	"protein metabolism;transport;other biological processes"	"non-structural extracellular;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00450"	"5476"	"ENSG00000064601"	"CTSA"	"B2R798; hsa:5476; P10619; Q561W6; Q5JZH1; Q96KJ2; Q9BR08; Q9BW68"	"Ciliary landscape"	"MHC class II antigen presentation; Glycosphingolipid metabolism; Neutrophil degranulation; Sialic acid metabolism; Defective NEU1 causes sialidosis"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2S7"	"Polymerase delta-interacting protein 2 OS=Homo sapiens OX=9606 GN=POLDIP2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"368"	"42.0"	"8.63"	"421.95"	"2.48"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04379, Pf08755"	"26073"	"ENSG00000004142"	"POLDIP2"	"B2R846; hsa:26073; Q96JE4; Q9Y2S7"	""	""	"0"	"0"	"69.7"	"70.6"	"63.2"	"73.6"	"56.3"	"61.0"	"79.4"	"87.4"	"98.9"	"189.5"	"472.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51114"	"Fragile X mental retardation syndrome-related protein 1 OS=Homo sapiens OX=9606 GN=FXR1 PE=1 SV=3"	"0.000"	""	"4"	"2"	"3"	"1"	"621"	"69.7"	"6.15"	"947.45"	"2.47"	"2"	"1"	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf16097, Pf17904, Pf18336"	"8087"	"ENSG00000114416"	"FXR1"	"A8K9B8; hsa:8087; P51114; Q7Z450; Q8N6R8"	"Bile acids synthesis and enterohepatic circulation"	"Signaling by BRAF and RAF1 fusions"	"2"	"0"	"40.5"	"38.8"	"43.9"	"58.1"	"37.1"	"57.0"	"64.3"	"59.6"	"99.3"	"302.0"	"417.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P51116"	"Fragile X mental retardation syndrome-related protein 2 OS=Homo sapiens OX=9606 GN=FXR2 PE=1 SV=2"	"0.000"	""	"4"	"2"	"3"	"1"	"673"	"74.2"	"6.23"	"943.22"	"2.47"	"2"	"1"	"developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf05641, Pf12235, Pf16096, Pf17904, Pf18336"	"9513"	"ENSG00000129245"	"FXR2"	"B2R9M2; D3DTQ1; hsa:9513; P51116; Q86V09; Q8WUM2"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"12.4"	"15.9"	"13.6"	"24.3"	"12.4"	"14.5"	"27.5"	"25.7"	"33.7"	"64.8"	"88.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P62253"	"Ubiquitin-conjugating enzyme E2 G1 OS=Homo sapiens OX=9606 GN=UBE2G1 PE=1 SV=3"	""	""	"7"	"1"	"1"	"1"	"170"	"19.5"	"5.30"	""	"2.47"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00179"	"7326"	"ENSG00000132388"	"UBE2G1"	"B2R7P2; D3DTK0; hsa:7326; P62253; Q99462"	"Parkin-ubiquitin proteasomal system pathway; Parkinson's disease pathway"	"Antigen processing: Ubiquitination & Proteasome degradation; Synthesis of active ubiquitin: roles of E1 and E2 enzymes"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14185"	"Dedicator of cytokinesis protein 1 OS=Homo sapiens OX=9606 GN=DOCK1 PE=1 SV=2"	"0.000"	""	"0"	"1"	"2"	"1"	"1865"	"215.2"	"7.56"	"275.12"	"2.47"	"1"	"1"	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00018, Pf06920, Pf14429, Pf16172, Pf20421, Pf20422"	"1793"	"ENSG00000150760"	"DOCK1"	"A9Z1Z5; hsa:1793; Q14185"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; Focal adhesion; Hepatocyte growth factor receptor signaling; Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; RAC2 GTPase cycle; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHOG GTPase cycle; DCC mediated attractive signaling; VEGFA-VEGFR2 Pathway; Factors involved in megakaryocyte development and platelet production; PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases"	"14"	"0"	"33.3"	"29.7"	"35.5"	"47.6"	"36.8"	"48.7"	"217.1"	"232.8"	"213.6"	"178.4"	"199.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00423"	"Echinoderm microtubule-associated protein-like 1 OS=Homo sapiens OX=9606 GN=EML1 PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"815"	"89.8"	"7.06"	"249.58"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf03451"	"2009"	"ENSG00000066629"	"EML1"	"hsa:2009; O00423; Q86U15; Q8N536; Q8N5C4; Q8WWL6"	""	""	"0"	"0"	"51.0"	"47.3"	"61.0"	"72.8"	"53.4"	"60.8"	"102.0"	"116.2"	"162.2"	"319.4"	"339.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q6ZNB6"	"NF-X1-type zinc finger protein NFXL1 OS=Homo sapiens OX=9606 GN=NFXL1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"911"	"101.3"	"8.41"	""	"2.47"	""	"1"	"other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01422"	"152518"	"ENSG00000170448"	"NFXL1"	"B1Q2K1; hsa:152518; Q6ZNB6; Q86VG1; Q8WVH1"	""	""	"0"	"0"	"12.0"	"10.6"	"10.5"	"12.2"	"12.4"	"8.2"	"15.1"	"20.7"	"19.2"	"33.9"	"52.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3B2"	"Exosome complex component CSL4 OS=Homo sapiens OX=9606 GN=EXOSC1 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"195"	"21.4"	"8.24"	"357.68"	"2.47"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity"	"Pf10447, Pf14382"	"51013"	"ENSG00000171311"	"EXOSC1"	"B2R9B3; hsa:51013; Q5JTH3; Q9Y3B2"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"6"	"0"	"9.1"	"16.1"	"11.1"	"20.6"	"10.2"	"8.6"	"17.1"	"24.3"	"34.5"	"83.5"	"107.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MF7"	"E3 SUMO-protein ligase NSE2 OS=Homo sapiens OX=9606 GN=NSMCE2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"2"	"1"	"247"	"27.9"	"7.74"	"289.87"	"2.47"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf11789"	"286053"	"ENSG00000156831"	"NSMCE2"	"hsa:286053; Q8N549; Q96MF7"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"44.2"	"39.2"	"50.5"	"66.2"	"44.0"	"45.1"	"78.9"	"86.4"	"104.9"	"292.7"	"361.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P05549"	"Transcription factor AP-2-alpha OS=Homo sapiens OX=9606 GN=TFAP2A PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"437"	"48.0"	"8.02"	""	"2.46"	""	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03299"	"7020"	"ENSG00000137203"	"TFAP2A"	"hsa:7020; P05549; Q13777; Q5TAV5; Q8N1C6"	"Neural crest differentiation; Corticotropin-releasing hormone signaling pathway; Ectoderm differentiation; Hypothetical craniofacial development pathway; Ebola virus infection in host; lncRNA in canonical Wnt signaling and colorectal cancer; Ciliary landscape; Galanin receptor pathway; SARS-CoV-2 innate immunity evasion and cell-specific immune response; CCL18 signaling pathway"	"Activation of the TFAP2 (AP-2) family of transcription factors; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors; TFAP2 (AP-2) family regulates transcription of cell cycle factors; Negative regulation of activity of TFAP2 (AP-2) family transcription factors; TFAP2 (AP-2) family regulates transcription of other transcription factors; TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation"	"17"	"0"	"21.4"	"20.2"	"21.1"	"31.3"	"21.5"	"21.5"	"44.5"	"45.7"	"62.1"	"120.2"	"145.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NQS1"	"Cell death regulator Aven OS=Homo sapiens OX=9606 GN=AVEN PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"362"	"38.5"	"4.98"	"249.07"	"2.46"	"1"	"1"	"other biological processes"	"other membranes;cytosol;other cell component"	""	""	"57099"	"ENSG00000169857"	"AVEN"	"hsa:57099; Q9NQS1"	""	"Regulation of the apoptosome activity"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZ21"	"Phosphatase and actin regulator 4 OS=Homo sapiens OX=9606 GN=PHACTR4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"702"	"78.2"	"6.62"	"386.17"	"2.46"	"1"	"1"	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf02755"	"65979"	"ENSG00000204138"	"PHACTR4"	"A2APK6; B9ZVW0; D3DPM3; hsa:65979; Q68DD4; Q6NUN6; Q8IZ21; Q8N384; Q9H395; Q9H6X0; Q9H8W6"	""	""	"0"	"0"	"6.9"	"5.5"	"11.6"	"15.1"	"11.7"	"8.0"	"16.0"	"16.3"	"28.9"	"89.5"	"239.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q06203"	"Amidophosphoribosyltransferase OS=Homo sapiens OX=9606 GN=PPAT PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"517"	"57.4"	"6.76"	""	"2.46"	""	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf00156, Pf13522"	"5471"	"ENSG00000128059"	"PPAT"	"hsa:5471; Q06203"	"Fluoropyrimidine activity; Metabolic reprogramming in colon cancer"	"Purine ribonucleoside monophosphate biosynthesis"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94854"	"Uncharacterized protein KIAA0754 OS=Homo sapiens OX=9606 GN=KIAA0754 PE=2 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1291"	"135.1"	"4.21"	"300.54"	"2.46"	"1"	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"45.2"	"26.8"	"42.5"	"53.8"	"40.3"	"39.4"	"50.7"	"49.8"	"58.1"	"112.8"	"181.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UEG4"	"Zinc finger protein 629 OS=Homo sapiens OX=9606 GN=ZNF629 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"869"	"96.6"	"7.93"	"256.27"	"2.46"	"1"	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"23361"	"ENSG00000102870"	"ZNF629"	"hsa:23361; Q15938; Q9UEG4"	""	""	"0"	"0"	"9.6"	"8.3"	"7.8"	"13.7"	"9.1"	"5.4"	"15.7"	"15.4"	"12.0"	"21.4"	"32.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O14639"	"Actin-binding LIM protein 1 OS=Homo sapiens OX=9606 GN=ABLIM1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"778"	"87.6"	"8.59"	""	"2.46"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf02209, Pf16182"	"3983"	"ENSG00000099204"	"ABLIM1"	"A6NI16; A6NJ06; A8MXA9; B3KVH2; hsa:3983; O14639; Q15039; Q5JVV1; Q5JVV2; Q5T6N2; Q5T6N3; Q5T6N5; Q68CQ9; Q9BUP1"	"Male infertility"	"DCC mediated attractive signaling"	"2"	"0"	"17.3"	"20.3"	"19.7"	"30.5"	"22.6"	"10.6"	"29.8"	"36.3"	"44.2"	"65.5"	"112.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NFT6"	"Protein DBF4 homolog B OS=Homo sapiens OX=9606 GN=DBF4B PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"615"	"67.2"	"8.34"	"262.08"	"2.45"	"1"	"1"	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf07535"	"80174"	"ENSG00000161692"	"DBF4B"	"D3DX56; hsa:80174; Q8NFT6; Q8TEX0; Q96B19; Q9H912"	""	""	"0"	"0"	"108.2"	"96.5"	"136.8"	"208.7"	"95.2"	"102.8"	"215.1"	"235.3"	"381.3"	"1252.9"	"1895.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P08069"	"Insulin-like growth factor 1 receptor OS=Homo sapiens OX=9606 GN=IGF1R PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1367"	"154.7"	"5.80"	""	"2.45"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;nucleus;other cell component"	"signal transduction activity or receptor binding;transporter activity;kinase activity;other molecular function"	"Pf00757, Pf01030, Pf07714"	"3480"	"ENSG00000140443"	"IGF1R"	"B1B5Y2; hsa:3480; P08069; Q14CV2; Q9UCC0"	"MicroRNAs in cardiomyocyte hypertrophy; Thyroid stimulating hormone (TSH) signaling pathway; Glioblastoma signaling pathways; Apoptosis; Focal adhesion; MECP2 and associated Rett syndrome; Factors and pathways affecting insulin-like growth factor (IGF1)-Akt signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway; Somatroph axis (GH) and its relationship to dietary restriction and aging; Ebola virus infection in host; Ras signaling; Breast cancer pathway; Hippo signaling regulation pathways; Hippo-Merlin signaling dysregulation; Head and neck squamous cell carcinoma; Endochondral ossification; EGFR tyrosine kinase inhibitor resistance; Endochondral ossification with skeletal dysplasias; Insulin signaling; Pleural mesothelioma; Modulation of PI3K-Akt-mTOR signaling by bioactive sphingolipids; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 5q35 copy number variation"	"Extra-nuclear estrogen signaling; IRS-related events triggered by IGF1R; Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R); SHC-related events triggered by IGF1R"	"29"	"0"	"11.3"	"3.3"	"19.3"	"21.4"	"13.1"	"16.6"	"19.1"	"21.6"	"18.4"	"34.0"	"92.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15049"	"Membrane protein MLC1 OS=Homo sapiens OX=9606 GN=MLC1 PE=1 SV=5"	""	""	"4"	"1"	"1"	"1"	"377"	"41.1"	"7.49"	""	"2.45"	""	"1"	"transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"23209"	"ENSG00000100427"	"MLC1"	"B3KW61; B7Z659; hsa:23209; Q15049; Q5JZ83; Q8TAG4; Q96RP5; Q9UGY8"	""	""	"0"	"0"	"95.5"	"37.4"	"168.2"	"158.8"	"90.3"	"105.5"	"148.1"	"116.3"	"146.8"	"241.0"	"468.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P031"	"Thyroid transcription factor 1-associated protein 26 OS=Homo sapiens OX=9606 GN=CCDC59 PE=1 SV=2"	"0.000"	""	"5"	"1"	"2"	"1"	"241"	"28.7"	"9.88"	"289.02"	"2.44"	"1"	"1"	""	"nucleus"	""	"Pf08524"	"29080"	"ENSG00000133773"	"CCDC59"	"hsa:29080; Q9H2V5; Q9NW62; Q9P031"	""	"Surfactant metabolism"	"1"	"0"	"18.8"	"18.8"	"15.9"	"21.4"	"17.6"	"18.1"	"26.0"	"24.3"	"22.4"	"50.7"	"58.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P04632"	"Calpain small subunit 1 OS=Homo sapiens OX=9606 GN=CAPNS1 PE=1 SV=1"	""	""	"9"	"1"	"1"	"1"	"268"	"28.3"	"5.20"	""	"2.44"	""	"1"	"protein metabolism;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	""	"826"	"ENSG00000126247"	"CAPNS1"	"A8K0P1; hsa:826; P04632; Q8WTX3; Q96EW0"	"Integrin-mediated cell adhesion"	"Formation of the cornified envelope; Degradation of the extracellular matrix; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models"	"4"	"0"	"47.6"	"41.5"	"53.4"	"59.8"	"42.4"	"34.5"	"66.7"	"73.8"	"86.9"	"172.9"	"244.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28290"	"Protein ITPRID2 OS=Homo sapiens OX=9606 GN=ITPRID2 PE=1 SV=3"	"0.001"	""	"0"	"1"	"2"	"1"	"1259"	"138.3"	"5.19"	"255.93"	"2.44"	"1"	"1"	""	"plasma membrane;other membranes;cytosol;nucleus"	"signal transduction activity or receptor binding;cytoskeletal activity"	"Pf14722, Pf14723"	"6744"	"ENSG00000138434"	"ITPRID2"	"A8K6T0; hsa:6744; P28290; Q68DA6; Q7Z7L2; Q8N1L3; Q8N263; Q8N7H2; Q8NEN5; Q96E36; Q96PW1"	""	""	"0"	"0"	"125.0"	"120.7"	"137.3"	"166.6"	"103.9"	"101.2"	"172.2"	"194.2"	"208.2"	"495.7"	"780.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PU8"	"Protein quaking OS=Homo sapiens OX=9606 GN=QKI PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"341"	"37.6"	"8.56"	"261.19"	"2.43"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;transport;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00013, Pf16544, Pf16551"	"9444"	"ENSG00000112531"	"QKI"	"hsa:9444; Q2I375; Q5MJQ1; Q969L9; Q96EJ3; Q96KA3; Q96PU6; Q96PU7; Q96PU8; Q9P0X6; Q9P0X7; Q9P0X8; Q9P0X9; Q9P0Y0; Q9P0Y1"	"VEGFA-VEGFR2 signaling; Exercise-induced circadian regulation"	"Signaling by BRAF and RAF1 fusions"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UL63"	"Muskelin OS=Homo sapiens OX=9606 GN=MKLN1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"735"	"84.7"	"6.34"	"241.74"	"2.43"	"1"	"1"	"cell adhesion;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01344, Pf06588, Pf13415"	"4289"	"ENSG00000128585"	"MKLN1"	"A4D1M8; A6NG43; hsa:4289; Q9NSK4; Q9NUS8; Q9UL63"	"Ciliary landscape"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P22681"	"E3 ubiquitin-protein ligase CBL OS=Homo sapiens OX=9606 GN=CBL PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"906"	"99.6"	"6.54"	""	"2.43"	""	"1"	"protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00627, Pf02262, Pf02761, Pf02762, Pf14447"	"867"	"ENSG00000110395"	"CBL"	"A3KMP8; hsa:867; P22681"	"RANKL/RANK signaling pathway; Prolactin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Physico-chemical features and toxicity-associated pathways; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; IL-4 signaling pathway; EGF/EGFR signaling pathway; Insulin signaling; IL-2 signaling pathway; 4p16.3 copy number variation; Interferon type I signaling pathways; ErbB signaling pathway; T-cell receptor signaling pathway"	"Regulation of signaling by CBL; Regulation of KIT signaling; Negative regulation of FLT3; Cargo recognition for clathrin-mediated endocytosis; Interleukin-6 signaling; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell; Signaling by CSF1 (M-CSF) in myeloid cells; Spry regulation of FGF signaling; TGF-beta receptor signaling activates SMADs; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; Constitutive Signaling by EGFRvIII; PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1; FLT3 signaling by CBL mutants"	"38"	"0"	"14.3"	"15.3"	"16.5"	"23.8"	"14.1"	"16.3"	"35.2"	"38.6"	"58.6"	"172.8"	"224.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A3KN83"	"Protein strawberry notch homolog 1 OS=Homo sapiens OX=9606 GN=SBNO1 PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"1393"	"154.2"	"7.88"	""	"2.43"	""	"1"	"other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf13871, Pf13872"	"55206"	"ENSG00000139697"	"SBNO1"	"A3KN83; hsa:55206; Q05C06; Q3ZTS3; Q9H3T8; Q9NVB2"	""	""	"0"	"0"	"2.4"	"2.8"	"0.0"	"1.9"	"4.0"	"2.2"	"12.5"	"15.8"	"35.6"	"134.5"	"219.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BVA0"	"Katanin p80 WD40 repeat-containing subunit B1 OS=Homo sapiens OX=9606 GN=KATNB1 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"655"	"72.3"	"7.56"	"289.25"	"2.43"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00400, Pf13925"	"10300"	"ENSG00000140854"	"KATNB1"	"A6NCG6; hsa:10300; O60620; Q9BVA0"	"Genes related to primary cilium development (based on CRISPR)"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6DN90"	"IQ motif and SEC7 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=IQSEC1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"963"	"108.2"	"6.93"	"409.08"	"2.42"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"ER/Golgi;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01369, Pf16453"	"9922"	"ENSG00000144711"	"IQSEC1"	"A0A087WWK8; hsa:9922; O94863; Q6DN90; Q96D85"	"EGF/EGFR signaling pathway"	""	"1"	"0"	"57.8"	"47.8"	"64.5"	"65.3"	"63.3"	"49.3"	"98.8"	"100.9"	"156.7"	"146.1"	"157.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14686"	"Nuclear receptor coactivator 6 OS=Homo sapiens OX=9606 GN=NCOA6 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"2063"	"219.0"	"9.36"	""	"2.42"	""	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf13820"	"23054"	"ENSG00000198646"	"NCOA6"	"A6NLF1; B2RMN5; E1P5P7; hsa:23054; Q14686; Q9NTZ9; Q9UH74; Q9UK86"	"Constitutive androstane receptor pathway; Nuclear receptors meta-pathway; Kleefstra syndrome"	"Cytoprotection by HMOX1; PPARA activates gene expression; Transcriptional regulation of white adipocyte differentiation; Formation of WDR5-containing histone-modifying complexes; Heme signaling; BMAL1:CLOCK,NPAS2 activates circadian gene expression; Transcriptional activation of mitochondrial biogenesis; Activation of anterior HOX genes in hindbrain development during early embryogenesis; Activation of gene expression by SREBF (SREBP); RORA activates gene expression"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"A6NED2"	"RCC1 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RCCD1 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"376"	"40.1"	"5.27"	""	"2.42"	""	"1"	"cell organization and biogenesis"	"plasma membrane;other membranes;cytosol;other cell component"	""	"Pf00415"	"91433"	"ENSG00000166965"	"RCCD1"	"A6NED2; B2RTP9; hsa:91433; Q29RX6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92547"	"DNA topoisomerase 2-binding protein 1 OS=Homo sapiens OX=9606 GN=TOPBP1 PE=1 SV=3"	"0.000"	""	"1"	"2"	"3"	"2"	"1522"	"170.6"	"6.96"	"491.67"	"2.42"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00533"	"11073"	"ENSG00000163781"	"TOPBP1"	"B7Z7W8; hsa:11073; Q7LGC1; Q92547; Q9UEB9"	"ATR signaling"	"Regulation of TP53 Activity through Phosphorylation; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51"	"7"	"0"	"177.1"	"182.6"	"204.2"	"240.6"	"184.6"	"174.3"	"291.7"	"314.6"	"405.0"	"925.0"	"1137.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30307"	"M-phase inducer phosphatase 3 OS=Homo sapiens OX=9606 GN=CDC25C PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"473"	"53.3"	"6.79"	"287.36"	"2.41"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf00581, Pf06617"	"995"	"ENSG00000158402"	"CDC25C"	"D3DQB8; hsa:995; P30307; Q96PL3; Q9H168; Q9H2E8; Q9H2E9; Q9H2F1"	"miRNA regulation of DNA damage response; Cell cycle; ATM signaling pathway; p53 transcriptional gene network; CCL18 signaling pathway; DNA damage response; Monoamine transport"	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain; Activation of ATR in response to replication stress; Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex; RHO GTPases activate PKNs; TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest; Cyclin A/B1/B2 associated events during G2/M transition; Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; Polo-like kinase mediated events"	"15"	"0"	"4.8"	"4.2"	"8.4"	"10.1"	"5.5"	"7.3"	"11.9"	"15.5"	"22.9"	"36.1"	"43.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWA4"	"Mitofusin-1 OS=Homo sapiens OX=9606 GN=MFN1 PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"741"	"84.1"	"6.33"	"244.04"	"2.41"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf00350, Pf04799"	"55669"	"ENSG00000171109"	"MFN1"	"A0A0C4DFN1; B2RAR1; D3DNR6; hsa:55669; O15323; O60639; Q8IWA4; Q9BZB5; Q9NWQ2"	""	"Factors involved in megakaryocyte development and platelet production; PINK1-PRKN Mediated Mitophagy; RHOT2 GTPase cycle"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JTZ9"	"Alanine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=AARS2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"985"	"107.3"	"6.27"	"262.99"	"2.41"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf01411, Pf07973"	"57505"	"ENSG00000124608"	"AARS2"	"A2RRN5; hsa:57505; Q5JTZ9; Q8N198; Q96D02; Q9ULF0"	"Primary ovarian insufficiency"	"Mitochondrial tRNA aminoacylation"	"2"	"0"	"39.9"	"35.6"	"46.0"	"57.7"	"31.6"	"35.0"	"67.2"	"81.2"	"112.2"	"753.2"	"1044.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7Z589"	"BRCA2-interacting transcriptional repressor EMSY OS=Homo sapiens OX=9606 GN=EMSY PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1322"	"141.4"	"9.33"	""	"2.41"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	"Pf03735"	"56946"	"ENSG00000158636"	"EMSY"	"B7ZKT8; B7ZKU0; B7ZKU2; hsa:56946; Q17RM7; Q4G109; Q7Z589; Q8NBU6; Q8TE50; Q9H8I9; Q9NRH0"	"Mesodermal commitment pathway"	""	"1"	"0"	"7.5"	"7.5"	"9.5"	"11.6"	"11.5"	"9.0"	"17.1"	"16.4"	"30.7"	"60.8"	"80.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BSQ5"	"Cerebral cavernous malformations 2 protein OS=Homo sapiens OX=9606 GN=CCM2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"444"	"48.8"	"5.54"	"304.45"	"2.40"	"1"	"1"	"cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"mitochondrion;other cell component"	""	"Pf16545"	"83605"	"ENSG00000136280"	"CCM2"	"A4D2L4; B3KUV0; D3DVL4; E9PDJ3; F5H0E1; F5H551; hsa:83605; Q71RE5; Q8TAT4; Q9BSQ5"	""	""	"0"	"0"	"7.2"	"4.7"	"18.3"	"21.3"	"13.0"	"11.4"	"17.5"	"20.5"	"30.7"	"100.0"	"111.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96RS6"	"NudC domain-containing protein 1 OS=Homo sapiens OX=9606 GN=NUDCD1 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"583"	"66.7"	"5.11"	""	"2.40"	""	"1"	"other biological processes"	"cytosol;nucleus"	""	"Pf04969"	"84955"	"ENSG00000120526"	"NUDCD1"	"B4DVX6; hsa:84955; Q4G130; Q8NDQ5; Q8NG18; Q96RS6; Q96SI4; Q9BVR5"	""	""	"0"	"0"	"35.5"	"34.4"	"48.0"	"56.2"	"35.8"	"28.4"	"93.5"	"90.0"	"168.3"	"833.5"	"1212.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUW1"	"Protein BRICK1 OS=Homo sapiens OX=9606 GN=BRK1 PE=1 SV=1"	"0.000"	""	"9"	"1"	"2"	"1"	"75"	"8.7"	"5.45"	"284.17"	"2.40"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"55845"	"ENSG00000254999"	"BRK1"	"B2R5E2; hsa:55845; Q8WUW1; Q9P082"	"Regulation of actin cytoskeleton"	"RAC1 GTPase cycle; VEGFA-VEGFR2 Pathway; Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; RAC2 GTPase cycle; RAC3 GTPase cycle"	"8"	"0"	"61.3"	"65.8"	"81.3"	"110.3"	"70.8"	"59.8"	"129.4"	"136.5"	"229.6"	"808.9"	"1090.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NZZ3"	"Charged multivesicular body protein 5 OS=Homo sapiens OX=9606 GN=CHMP5 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"219"	"24.6"	"4.83"	"270.10"	"2.38"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf03357"	"51510"	"ENSG00000086065"	"CHMP5"	"B2RD95; B4DIR6; hsa:51510; Q5VXW2; Q96AV2; Q9HB68; Q9NYS4; Q9NZZ3; Q9Y323"	"Ferroptosis"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"3"	"0"	"84.0"	"73.8"	"106.2"	"177.2"	"90.5"	"88.8"	"182.2"	"195.2"	"246.8"	"505.1"	"830.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULR3"	"Protein phosphatase 1H OS=Homo sapiens OX=9606 GN=PPM1H PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"514"	"56.4"	"6.60"	"313.95"	"2.38"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00481"	"57460"	"ENSG00000111110"	"PPM1H"	"B1Q2A9; B2RXG4; hsa:57460; Q6PI86; Q9ULR3"	""	""	"0"	"0"	"6.0"	"2.8"	"3.8"	"9.1"	"5.2"	"6.7"	"9.5"	"10.0"	"14.3"	"70.2"	"113.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14527"	"Helicase-like transcription factor OS=Homo sapiens OX=9606 GN=HLTF PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"1009"	"113.9"	"8.60"	"353.57"	"2.37"	"1"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf08797, Pf13923"	"6596"	"ENSG00000071794"	"HLTF"	"D3DNH3; hsa:6596; Q14527; Q14536; Q16051; Q7KYJ6; Q86YA5; Q92652; Q96KM9"	"Retinoblastoma gene in cancer"	"E3 ubiquitin ligases ubiquitinate target proteins"	"2"	"0"	"11.6"	"10.7"	"12.0"	"11.0"	"11.4"	"10.5"	"8.1"	"10.3"	"16.7"	"13.0"	"22.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WVB6"	"Chromosome transmission fidelity protein 18 homolog OS=Homo sapiens OX=9606 GN=CHTF18 PE=1 SV=1"	"0.000"	""	"2"	"1"	"4"	"1"	"975"	"107.3"	"7.21"	"281.69"	"2.37"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00004"	"63922"	"ENSG00000127586"	"CHTF18"	"B7ZBA2; D3DU68; hsa:63922; Q7Z6Y4; Q7Z6Y6; Q8WVB6; Q9BR83; Q9BRG5; Q9H7K3"	"Gastric cancer network 2; 7q11.23 copy number variation syndrome"	"Polymerase switching on the C-strand of the telomere"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRK6"	"ATP-binding cassette sub-family B member 10, mitochondrial OS=Homo sapiens OX=9606 GN=ABCB10 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"738"	"79.1"	"9.85"	"299.85"	"2.37"	"1"	"1"	"other metabolic processes;stress response;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf00005, Pf00664"	"23456"	"ENSG00000135776"	"ABCB10"	"hsa:23456; Q13040; Q6P1Q8; Q9H3V0; Q9NRK6"	""	"Mitochondrial ABC transporters"	"1"	"0"	"5.0"	"4.3"	"10.5"	"13.4"	"6.4"	"4.8"	"15.5"	"14.9"	"25.8"	"90.5"	"154.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O15254"	"Peroxisomal acyl-coenzyme A oxidase 3 OS=Homo sapiens OX=9606 GN=ACOX3 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"700"	"77.6"	"7.25"	""	"2.36"	""	"1"	"other metabolic processes;other biological processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf01756, Pf02770"	"8310"	"ENSG00000087008"	"ACOX3"	"hsa:8310; O15254; Q96AJ8"	"PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Omega-3 / omega-6 fatty acid synthesis"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15363"	"Transmembrane emp24 domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TMED2 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"201"	"22.7"	"5.17"	""	"2.36"	""	"1"	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;ER/Golgi;other cell component"	"signal transduction activity or receptor binding"	"Pf01105"	"10959"	"ENSG00000086598"	"TMED2"	"hsa:10959; Q15363"	"5q35 copy number variation"	"COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; Pre-NOTCH Processing in Golgi; COPII-mediated vesicle transport; Cargo concentration in the ER"	"6"	"0"	"12.2"	"12.8"	"17.0"	"44.2"	"17.4"	"15.4"	"40.5"	"40.7"	"85.7"	"341.3"	"422.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P06396"	"Gelsolin OS=Homo sapiens OX=9606 GN=GSN PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"782"	"85.6"	"6.28"	""	"2.36"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00626"	"2934"	"ENSG00000148180"	"GSN"	"A2A418; A8MUD1; A8MYN7; B7Z373; B7Z5V1; F5H1A8; hsa:2934; P06396; Q5T0I2; Q8WVV7"	"Ebola virus infection in host; Regulation of actin cytoskeleton"	"Neutrophil degranulation; Amyloid fiber formation; Sensory processing of sound by outer hair cells of the cochlea; Caspase-mediated cleavage of cytoskeletal proteins"	"6"	"0"	"285.6"	"204.1"	"220.7"	"289.1"	"188.2"	"240.8"	"281.7"	"263.9"	"288.4"	"501.3"	"591.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3T9"	"Nucleolar complex protein 2 homolog OS=Homo sapiens OX=9606 GN=NOC2L PE=1 SV=4"	"0.000"	""	"3"	"2"	"3"	"2"	"749"	"84.9"	"5.62"	"889.41"	"2.36"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf03715"	"26155"	"ENSG00000188976"	"NOC2L"	"hsa:26155; Q5SVA3; Q9BTN6; Q9Y3T9"	"1p36 copy number variation syndrome"	"Regulation of TP53 Activity through Phosphorylation"	"2"	"0"	"24.7"	"24.2"	"32.2"	"42.8"	"26.1"	"27.8"	"44.5"	"46.6"	"66.2"	"149.4"	"220.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75569"	"Interferon-inducible double-stranded RNA-dependent protein kinase activator A OS=Homo sapiens OX=9606 GN=PRKRA PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"313"	"34.4"	"8.41"	"248.51"	"2.36"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf00035"	"8575"	"ENSG00000180228"	"PRKRA"	"A8K3I6; hsa:8575; O75569; Q53G24; Q6X7T5; Q8NDK4"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host"	"MicroRNA (miRNA) biogenesis; Small interfering RNA (siRNA) biogenesis"	"4"	"0"	"6.2"	"5.1"	"6.6"	"12.3"	"3.1"	"5.2"	"5.3"	"9.1"	"11.7"	"25.3"	"26.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56556"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 6 OS=Homo sapiens OX=9606 GN=NDUFA6 PE=1 SV=4"	"0.000"	""	"6"	"1"	"2"	"1"	"128"	"15.1"	"9.98"	"369.67"	"2.36"	"1"	"1"	"cell organization and biogenesis;other metabolic processes;stress response;transport"	"other membranes;mitochondrion"	"transporter activity"	"Pf05347"	"4700"	"ENSG00000184983; ENSG00000272765; ENSG00000273397; ENSG00000277365; ENSG00000281013"	"NDUFA6"	"B2RE54; hsa:4700; O43675; P56556; Q6FGW0; Q6IBT8; Q6IC39"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"97.5"	"101.1"	"107.0"	"128.2"	"104.7"	"96.3"	"178.6"	"183.0"	"242.2"	"635.7"	"763.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96D71"	"RalBP1-associated Eps domain-containing protein 1 OS=Homo sapiens OX=9606 GN=REPS1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"796"	"86.6"	"5.69"	""	"2.36"	""	"1"	"transport"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf12763"	"85021"	"ENSG00000135597"	"REPS1"	"B7ZBZ8; B7ZBZ9; B7ZC00; hsa:85021; J3KP76; Q5JWJ5; Q5JWJ6; Q5JWJ7; Q8NDR7; Q8WU62; Q96D71; Q9BXY9"	""	"Cargo recognition for clathrin-mediated endocytosis"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75191"	"Xylulose kinase OS=Homo sapiens OX=9606 GN=XYLB PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"536"	"58.3"	"5.86"	""	"2.36"	""	"1"	"other metabolic processes"	"cytosol"	"kinase activity;other molecular function"	"Pf00370, Pf02782"	"9942"	"ENSG00000093217"	"XYLB"	"B2RAW4; B4DDT2; B9EH64; hsa:9942; O75191"	""	"Formation of xylulose-5-phosphate"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H5Y7"	"SLIT and NTRK-like protein 6 OS=Homo sapiens OX=9606 GN=SLITRK6 PE=2 SV=3"	""	""	"2"	"1"	"1"	"1"	"841"	"95.0"	"6.52"	""	"2.36"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;other cell component"	""	"Pf13855"	"84189"	"ENSG00000184564"	"SLITRK6"	"A8K9S8; hsa:84189; Q495Q0; Q6AW93; Q9H5Y7; Q9HAA8; Q9NT60"	""	"Receptor-type tyrosine-protein phosphatases"	"1"	"0"	"58.7"	"52.3"	"57.2"	"68.4"	"42.4"	"43.7"	"95.6"	"121.7"	"135.5"	"333.3"	"477.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27708"	"CAD protein OS=Homo sapiens OX=9606 GN=CAD PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"2225"	"242.8"	"6.46"	"338.40"	"2.36"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00117, Pf00185, Pf00988, Pf01979, Pf02142, Pf02729, Pf02786, Pf02787"	"790"	"ENSG00000084774"	"CAD"	"D6W552; hsa:790; P27708; Q6P0Q0; Q96CK3"	"Endothelin pathways; Amino acid metabolism; Pyrimidine metabolism"	"Pyrimidine biosynthesis"	"4"	"0"	"58.4"	"45.3"	"66.3"	"88.6"	"52.4"	"50.9"	"84.0"	"81.8"	"105.6"	"421.6"	"701.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14617"	"AP-3 complex subunit delta-1 OS=Homo sapiens OX=9606 GN=AP3D1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1153"	"130.1"	"8.48"	"657.34"	"2.35"	"2"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01602, Pf06375"	"8943"	"ENSG00000065000"	"AP3D1"	"hsa:8943; O00202; O14617; O75262; Q59HF5; Q96G11; Q9H3C6"	""	""	"0"	"0"	"0.0"	"3.2"	"2.6"	"2.3"	"0.0"	"0.0"	"5.3"	"7.5"	"19.1"	"47.5"	"65.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61081"	"NEDD8-conjugating enzyme Ubc12 OS=Homo sapiens OX=9606 GN=UBE2M PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"183"	"20.9"	"7.69"	"275.08"	"2.35"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus"	"other molecular function"	"Pf00179"	"9040"	"ENSG00000130725"	"UBE2M"	"hsa:9040; O76069; P61081; Q8VC50"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Dectin-1 mediated noncanonical NF-kB signaling; NIK-->noncanonical NF-kB signaling; Neddylation; TGF-beta receptor signaling activates SMADs"	"5"	"0"	"52.0"	"37.5"	"75.2"	"82.2"	"59.0"	"62.5"	"80.6"	"92.5"	"95.9"	"381.4"	"1030.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BZC1"	"CUGBP Elav-like family member 4 OS=Homo sapiens OX=9606 GN=CELF4 PE=1 SV=1"	""	""	"5"	"1"	"1"	"1"	"486"	"51.9"	"8.00"	""	"2.35"	""	"1"	"cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076"	"56853"	"ENSG00000101489"	"CELF4"	"hsa:56853; Q59EN7; Q86XB9; Q8N2M6; Q9BQ96; Q9BZC1; Q9NR84; Q9NR85"	"mRNA processing"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O60911"	"Cathepsin L2 OS=Homo sapiens OX=9606 GN=CTSV PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"334"	"37.3"	"8.76"	"269.78"	"2.35"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"non-structural extracellular;other cytoplasmic organelle"	"enzyme regulator activity;other molecular function"	"Pf00112, Pf08246"	"1515"	"ENSG00000136943"	"CTSV"	"hsa:1515; O60233; O60911; Q2TB86; Q5T1U0"	"Endochondral ossification; Endochondral ossification with skeletal dysplasias; Pancreatic cancer subtypes"	"MHC class II antigen presentation; Assembly of collagen fibrils and other multimeric structures; RUNX1 regulates transcription of genes involved in differentiation of keratinocytes; Trafficking and processing of endosomal TLR; Endosomal/Vacuolar pathway; Activation of Matrix Metalloproteinases"	"10"	"0"	"37.2"	"35.5"	"61.6"	"68.5"	"30.1"	"40.9"	"262.8"	"298.1"	"438.5"	"1179.0"	"1338.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P12110"	"Collagen alpha-2(VI) chain OS=Homo sapiens OX=9606 GN=COL6A2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1019"	"108.5"	"6.21"	""	"2.35"	""	"1"	"cell adhesion;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00092, Pf01391"	"1292"	"ENSG00000142173"	"COL6A2"	"hsa:1292; P12110; Q13909; Q13910; Q13911; Q14048; Q14049; Q16259; Q16597; Q6P0Q1; Q9UML3; Q9Y4S8"	"miRNA targets in ECM and membrane receptors; Focal adhesion; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; PI3K-Akt signaling pathway"	"Collagen degradation; Signaling by PDGF; Assembly of collagen fibrils and other multimeric structures; Integrin cell surface interactions; ECM proteoglycans; NCAM1 interactions; Collagen chain trimerization"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRX2"	"39S ribosomal protein L17, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL17 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"175"	"20.0"	"10.11"	"277.77"	"2.34"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01196"	"63875"	"ENSG00000158042"	"MRPL17"	"D3DQU3; hsa:63875; Q6IAH8; Q96Q53; Q9C066; Q9NRX2"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"46.0"	"45.3"	"47.5"	"59.6"	"41.7"	"51.0"	"74.5"	"78.4"	"81.8"	"255.3"	"405.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WY36"	"HMG box transcription factor BBX OS=Homo sapiens OX=9606 GN=BBX PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"941"	"105.1"	"8.79"	"257.20"	"2.34"	"1"	"1"	"developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf09667"	"56987"	"ENSG00000114439"	"BBX"	"A2RRM7; hsa:56987; Q2TAJ1; Q7L3J8; Q7LBY8; Q8NDB0; Q8WY35; Q8WY36; Q9H0J6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NQ75"	"Cas scaffolding protein family member 4 OS=Homo sapiens OX=9606 GN=CASS4 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"786"	"87.1"	"7.08"	""	"2.33"	""	"1"	"cell adhesion;signal transduction;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	"Pf08824, Pf12026, Pf14604"	"57091"	"ENSG00000087589"	"CASS4"	"E1P5Z8; hsa:57091; Q5QPD6; Q96K09; Q9BYL5; Q9NQ75"	""	""	"0"	"0"	"22.8"	"13.9"	"22.4"	"41.3"	"31.6"	"42.8"	"96.2"	"97.6"	"126.2"	"289.0"	"363.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14202"	"Zinc finger MYM-type protein 3 OS=Homo sapiens OX=9606 GN=ZMYM3 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1370"	"152.3"	"6.35"	"240.90"	"2.33"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf06467, Pf12012"	"9203"	"ENSG00000147130"	"ZMYM3"	"D3DVV3; hsa:9203; O15089; Q14202; Q96E26"	"Orexin receptor pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P40938"	"Replication factor C subunit 3 OS=Homo sapiens OX=9606 GN=RFC3 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"356"	"40.5"	"8.34"	""	"2.33"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf13177"	"5983"	"ENSG00000133119"	"RFC3"	"C9JU95; hsa:5983; O15252; P40938; Q5W0E8"	"Gastric cancer network 2; Retinoblastoma gene in cancer; DNA replication; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum ; DNA mismatch repair"	"PCNA-Dependent Long Patch Base Excision Repair; Regulation of TP53 Activity through Phosphorylation; Activation of ATR in response to replication stress; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Termination of translesion DNA synthesis; HDR through Homologous Recombination (HRR); Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Translesion synthesis by REV1; Translesion synthesis by POLK; Translesion synthesis by POLI; Recognition of DNA damage by PCNA-containing replication complex; Dual Incision in GG-NER; Translesion Synthesis by POLH; Gap-filling DNA repair synthesis and ligation in GG-NER; Polymerase switching on the C-strand of the telomere; Polymerase switching"	"28"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z3K3"	"Pogo transposable element with ZNF domain OS=Homo sapiens OX=9606 GN=POGZ PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1410"	"155.2"	"7.40"	"243.27"	"2.33"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03184, Pf03221"	"23126"	"ENSG00000143442"	"POGZ"	"B4DTP8; B4DYL9; B7ZBY5; E9PM80; hsa:23126; O75049; Q3LIC4; Q5SZS1; Q5SZS2; Q5SZS3; Q5SZS4; Q7Z3K3; Q8TDZ7; Q9Y4X7"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P78556"	"C-C motif chemokine 20 OS=Homo sapiens OX=9606 GN=CCL20 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"96"	"10.8"	"8.94"	""	"2.32"	""	"1"	"cell-cell signaling;stress response;signal transduction;other biological processes"	"non-structural extracellular"	"signal transduction activity or receptor binding"	"Pf00048"	"6364"	"ENSG00000115009"	"CCL20"	"hsa:6364; P78556; Q53S51; Q99664"	"Ebstein-Barr virus LMP1 signaling; Glucocorticoid receptor pathway; Nuclear receptors meta-pathway; Chemokine signaling pathway; IL-18 signaling pathway; Overview of proinflammatory and profibrotic mediators; Immune infiltration in pancreatic cancer; IL-26 signaling pathways"	"G alpha (i) signalling events; Chemokine receptors bind chemokines; Interleukin-10 signaling"	"11"	"0"	"212.8"	"56.9"	"287.8"	"314.9"	"177.7"	"194.3"	"260.3"	"238.1"	"276.6"	"420.4"	"837.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14181"	"DNA polymerase alpha subunit B OS=Homo sapiens OX=9606 GN=POLA2 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"598"	"65.9"	"5.24"	""	"2.32"	""	"1"	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;transport"	"cytosol;nucleus"	"nucleic acid binding activity"	"Pf04042, Pf08418"	"23649"	"ENSG00000014138"	"POLA2"	"B4DNB4; hsa:23649; Q14181; Q9BPV3"	"Pyrimidine metabolism; G1 to S cell cycle control; DNA replication"	"Activation of the pre-replicative complex; Defective pyroptosis; Inhibition of replication initiation of damaged DNA by RB1/E2F1; Polymerase switching on the C-strand of the telomere; Telomere C-strand synthesis initiation; DNA replication initiation; Polymerase switching; Removal of the Flap Intermediate"	"12"	"0"	"16.0"	"15.6"	"20.7"	"22.8"	"13.4"	"19.2"	"47.7"	"46.9"	"78.1"	"334.2"	"488.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UNW9"	"RNA-binding protein Nova-2 OS=Homo sapiens OX=9606 GN=NOVA2 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"492"	"49.0"	"8.16"	"244.71"	"2.32"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00013"	"4858"	"ENSG00000104967"	"NOVA2"	"hsa:4858; O43267; Q9UEA1; Q9UNW9"	""	""	"0"	"0"	"116.2"	"101.5"	"118.3"	"141.8"	"118.5"	"117.3"	"151.2"	"159.4"	"162.7"	"341.7"	"486.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NVJ2"	"ADP-ribosylation factor-like protein 8B OS=Homo sapiens OX=9606 GN=ARL8B PE=1 SV=1"	""	""	"8"	"1"	"1"	"1"	"186"	"21.5"	"8.43"	""	"2.32"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00025"	"55207"	"ENSG00000134108"	"ARL8B"	"B4DI85; hsa:55207; Q9NVJ2"	"Ciliary landscape"	""	"1"	"0"	"150.4"	"39.8"	"220.0"	"181.5"	"136.2"	"165.3"	"177.4"	"141.6"	"200.5"	"313.8"	"490.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7LBR1"	"Charged multivesicular body protein 1b OS=Homo sapiens OX=9606 GN=CHMP1B PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"199"	"22.1"	"8.10"	""	"2.32"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf03357"	"57132"	"ENSG00000255112"	"CHMP1B"	"hsa:57132; Q7LBR1; Q96E89; Q9HD41"	""	""	"0"	"0"	"172.9"	"122.4"	"169.7"	"213.6"	"160.1"	"196.5"	"509.7"	"515.3"	"759.7"	"692.7"	"502.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96RG2"	"PAS domain-containing serine/threonine-protein kinase OS=Homo sapiens OX=9606 GN=PASK PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1323"	"142.8"	"4.86"	""	"2.32"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf13426"	"23178"	"ENSG00000115687"	"PASK"	"G5E9F1; hsa:23178; Q05BE4; Q68DY3; Q6GSJ5; Q86XH6; Q96RG2; Q99763; Q9UFR7"	"2q37 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BPZ3"	"Polyadenylate-binding protein-interacting protein 2 OS=Homo sapiens OX=9606 GN=PAIP2 PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"127"	"15.0"	"4.12"	"270.94"	"2.32"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07145"	"51247"	"ENSG00000120727"	"PAIP2"	"B2RBI1; D3DQC6; hsa:51247; Q49A06; Q9BPZ3; Q9H0Y5; Q9P0Q8"	""	""	"0"	"0"	"268.8"	"230.1"	"240.1"	"250.0"	"197.8"	"235.3"	"272.8"	"267.3"	"283.3"	"507.1"	"771.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1N0"	"Coiled-coil and C2 domain-containing protein 1A OS=Homo sapiens OX=9606 GN=CC2D1A PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"951"	"104.0"	"8.09"	"448.30"	"2.31"	"1"	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00168"	"54862"	"ENSG00000132024; ENSG00000288293"	"CC2D1A"	"hsa:54862; Q6P1N0; Q7Z435; Q86XV0; Q8NF89; Q9H603; Q9NXI1"	"Sudden infant death syndrome (SIDS) susceptibility pathways"	""	"1"	"0"	"74.0"	"68.9"	"78.1"	"109.1"	"75.5"	"64.9"	"93.0"	"107.5"	"144.7"	"283.6"	"490.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2T3"	"Guanine deaminase OS=Homo sapiens OX=9606 GN=GDA PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"454"	"51.0"	"5.68"	""	"2.31"	""	"1"	"other metabolic processes;developmental processes"	"cytosol"	"other molecular function"	"Pf01979"	"9615"	"ENSG00000119125"	"GDA"	"B4DTY5; hsa:9615; Q5SZC7; Q9H335; Q9ULG2; Q9Y2T3"	""	"Purine catabolism"	"1"	"0"	"336.7"	"99.8"	"404.8"	"361.6"	"295.1"	"335.1"	"295.1"	"220.8"	"248.3"	"302.8"	"712.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q3SXY8"	"ADP-ribosylation factor-like protein 13B OS=Homo sapiens OX=9606 GN=ARL13B PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"428"	"48.6"	"6.62"	"289.77"	"2.31"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00025"	"200894"	"ENSG00000169379"	"ARL13B"	"D3DN29; G3V1S8; hsa:200894; Q3SXY8; Q504W8; Q8TCL5"	"Genes related to primary cilium development (based on CRISPR); Joubert syndrome; Ciliopathies; Bardet-Biedl syndrome"	"Aggrephagy; RHOQ GTPase cycle; RHOJ GTPase cycle; Late endosomal microautophagy; ARL13B-mediated ciliary trafficking of INPP5E; Chaperone Mediated Autophagy"	"10"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3D0"	"Cytosolic iron-sulfur assembly component 2B OS=Homo sapiens OX=9606 GN=CIAO2B PE=1 SV=1"	"0.001"	""	"4"	"1"	"2"	"1"	"163"	"17.7"	"5.19"	"250.40"	"2.30"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes"	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf01883"	"51647"	"ENSG00000166595"	"CIAO2B"	"hsa:51647; Q9Y3D0"	"Iron-sulfur cluster biogenesis; 2q11.2 copy number variation syndrome"	"Cytosolic iron-sulfur cluster assembly"	"3"	"0"	"60.6"	"51.3"	"68.4"	"79.1"	"60.0"	"59.6"	"99.7"	"104.1"	"117.5"	"267.3"	"345.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96BN2"	"Transcriptional adapter 1 OS=Homo sapiens OX=9606 GN=TADA1 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"335"	"37.4"	"7.39"	"256.50"	"2.30"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf12767"	"117143"	"ENSG00000152382"	"TADA1"	"A8K4J9; hsa:117143; Q96BN2"	""	"HATs acetylate histones"	"1"	"0"	"13.8"	"7.0"	"15.2"	"26.7"	"7.2"	"7.4"	"12.5"	"15.7"	"18.9"	"71.1"	"88.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35270"	"Sepiapterin reductase OS=Homo sapiens OX=9606 GN=SPR PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"261"	"28.0"	"8.05"	"272.45"	"2.30"	"1"	"1"	"other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00106"	"6697"	"ENSG00000116096"	"SPR"	"A8K741; D6W5H2; hsa:6697; P35270; Q53GI9; Q9UBB1"	""	"eNOS activation; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	"2"	"0"	"9.9"	"8.1"	"12.6"	"17.8"	"11.7"	"8.6"	"22.1"	"21.4"	"37.1"	"117.9"	"224.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UFC0"	"Leucine-rich repeat and WD repeat-containing protein 1 OS=Homo sapiens OX=9606 GN=LRWD1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"647"	"70.8"	"7.21"	"260.67"	"2.30"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	""	"222229"	"ENSG00000161036"	"LRWD1"	"A8K4K2; B2R9G2; hsa:222229; Q8N0T9; Q8WV43; Q96GJ2; Q9UFC0"	"Male infertility"	""	"1"	"0"	"30.6"	"25.4"	"51.0"	"73.8"	"39.4"	"35.7"	"65.7"	"74.9"	"137.0"	"419.7"	"454.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P54727"	"UV excision repair protein RAD23 homolog B OS=Homo sapiens OX=9606 GN=RAD23B PE=1 SV=1"	""	""	"1"	"1"	"1"	"1"	"409"	"43.1"	"4.84"	""	"2.30"	""	"1"	"protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00627, Pf09280"	"5887"	"ENSG00000119318"	"RAD23B"	"B3KWK8; G5E9P0; hsa:5887; P54727; Q7Z5K8; Q8WUB0"	"Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"Josephin domain DUBs; Formation of Incision Complex in GG-NER; DNA Damage Recognition in GG-NER; N-glycan trimming in the ER and Calnexin/Calreticulin cycle"	"7"	"0"	"148.2"	"185.3"	"144.4"	"196.7"	"152.5"	"139.0"	"225.8"	"232.0"	"244.9"	"418.1"	"542.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13613"	"Myotubularin-related protein 1 OS=Homo sapiens OX=9606 GN=MTMR1 PE=1 SV=4"	"0.001"	""	"1"	"1"	"2"	"1"	"665"	"74.6"	"7.14"	"249.14"	"2.30"	"1"	"1"	"other metabolic processes;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf02893, Pf06602"	"8776"	"ENSG00000063601"	"MTMR1"	"A0A024RC07; hsa:8776; Q13613; Q9UBX6; Q9UEM0; Q9UQD5"	""	"RHOF GTPase cycle; Synthesis of PIPs at the plasma membrane"	"2"	"0"	"90.6"	"86.6"	"88.1"	"86.1"	"65.8"	"97.2"	"337.6"	"365.2"	"457.4"	"480.2"	"349.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P17706"	"Tyrosine-protein phosphatase non-receptor type 2 OS=Homo sapiens OX=9606 GN=PTPN2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"415"	"48.4"	"8.29"	""	"2.29"	""	"1"	"protein metabolism;other metabolic processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00102"	"5771"	"ENSG00000175354"	"PTPN2"	"A8K955; A8MXU3; hsa:5771; K7ENG3; P17706; Q96AU5; Q96HR2"	"Immune response to tuberculosis; 5q35 copy number variation"	"Negative regulation of MET activity; Interleukin-37 signaling"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12860"	"Contactin-1 OS=Homo sapiens OX=9606 GN=CNTN1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1018"	"113.2"	"5.90"	"295.98"	"2.29"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00041, Pf07679, Pf13927"	"1272"	"ENSG00000018236"	"CNTN1"	"A8K0H9; A8K0Y3; hsa:1272; Q12860; Q12861; Q14030; Q7M4P0; Q8N466"	""	"Activated NOTCH1 Transmits Signal to the Nucleus; NOTCH2 Activation and Transmission of Signal to the Nucleus; Neurofascin interactions"	"4"	"0"	"4.4"	"4.9"	"6.8"	"10.2"	"3.0"	"1.6"	"9.5"	"12.6"	"14.9"	"54.8"	"117.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15024"	"Exosome complex component RRP42 OS=Homo sapiens OX=9606 GN=EXOSC7 PE=1 SV=3"	"0.000"	""	"4"	"1"	"2"	"1"	"291"	"31.8"	"5.19"	"297.76"	"2.29"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01138, Pf03725"	"23016"	"ENSG00000075914"	"EXOSC7"	"hsa:23016; Q15024; Q96E72"	"Ciliary landscape"	"ATF4 activates genes in response to endoplasmic reticulum  stress; Major pathway of rRNA processing in the nucleolus and cytosol; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA; mRNA decay by 3' to 5' exoribonuclease"	"7"	"0"	"15.7"	"18.5"	"28.0"	"32.8"	"22.8"	"13.6"	"41.0"	"35.7"	"52.5"	"164.5"	"232.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0DPB5"	"Protein POLR1D, isoform 2 OS=Homo sapiens OX=9606 GN=POLR1D PE=1 SV=1"	"0.000"	""	"6"	"1"	"2"	"1"	"122"	"14.3"	"9.88"	"307.35"	"2.29"	"1"	"1"	""	"cytosol;nucleus"	""	""	"51082"	"ENSG00000186184"	"POLR1D"	"P0DPB5; Q5TBX2; Q96BR3; Q9Y2S0"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination"	"16"	"0"	"102.7"	"104.6"	"112.2"	"120.7"	"96.6"	"97.8"	"132.2"	"134.9"	"175.7"	"270.0"	"310.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9H977"	"WD repeat-containing protein 54 OS=Homo sapiens OX=9606 GN=WDR54 PE=1 SV=1"	""	""	"4"	"1"	"1"	"1"	"334"	"35.9"	"6.20"	""	"2.29"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytoskeleton;other cell component"	"other molecular function"	""	"84058"	"ENSG00000005448"	"WDR54"	"B9A049; D6W5I3; hsa:84058; Q53H85; Q86V45; Q9H977"	""	""	"0"	"0"	"70.0"	"20.0"	"110.9"	"181.7"	"66.2"	"60.4"	"163.6"	"152.1"	"237.8"	"415.8"	"910.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4X1"	"Regulator of cell cycle RGCC OS=Homo sapiens OX=9606 GN=RGCC PE=1 SV=1"	"0.000"	""	"8"	"1"	"2"	"1"	"137"	"14.6"	"4.75"	"313.34"	"2.29"	"1"	"1"	"cell cycle OR cell proliferation;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf15151"	"28984"	"ENSG00000102760"	"RGCC"	"hsa:28984; Q6NZ48; Q9H4X1; Q9UL69"	""	"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain"	"1"	"0"	"7.1"	"7.2"	"12.1"	"15.2"	"10.2"	"8.8"	"10.0"	"13.5"	"12.0"	"10.8"	"18.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y399"	"28S ribosomal protein S2, mitochondrial OS=Homo sapiens OX=9606 GN=MRPS2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"296"	"33.2"	"9.26"	"267.29"	"2.28"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf00318"	"51116"	"ENSG00000122140"	"MRPS2"	"hsa:51116; Q5T899; Q9BSQ4; Q9Y399"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"72.4"	"79.1"	"116.2"	"158.5"	"79.5"	"59.3"	"144.4"	"167.2"	"170.5"	"363.3"	"553.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12974"	"Protein tyrosine phosphatase type IVA 2 OS=Homo sapiens OX=9606 GN=PTP4A2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"167"	"19.1"	"8.37"	"366.71"	"2.28"	"1"	"1"	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00102"	"8073"	"ENSG00000184007"	"PTP4A2"	"A8K9I8; B4DM39; D3DPP0; E9PGJ6; hsa:8073; O00649; Q12974; Q15197; Q15259; Q15260; Q15261; R4GN50"	""	"RAB geranylgeranylation"	"1"	"0"	"43.1"	"40.4"	"51.2"	"54.9"	"34.3"	"36.9"	"82.0"	"83.5"	"104.1"	"255.0"	"358.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00338"	"L-lactate dehydrogenase A chain OS=Homo sapiens OX=9606 GN=LDHA PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"332"	"36.7"	"8.27"	""	"2.27"	""	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00056, Pf02866"	"3939"	"ENSG00000134333; ENSG00000288299"	"LDHA"	"B4DKQ2; B7Z5E3; D3DQY3; F8W819; hsa:3939; P00338; Q53G53; Q6IBM7; Q6ZNV1; Q9UDE8; Q9UDE9"	"Cori cycle; HIF1A and PPARG regulation of glycolysis; Photodynamic therapy-induced HIF-1 survival signaling; VEGFA-VEGFR2 signaling; Amino acid metabolism; Clear cell renal cell carcinoma pathways; PI3K/AKT/mTOR - vitamin D3 signaling; Metabolic reprogramming in colon cancer; Aerobic glycolysis; Glycolysis in senescence; Orexin receptor pathway; CCL18 signaling pathway; Glucose metabolism in triple-negative breast cancer cells; Warburg effect modulated by deubiquitinating enzymes and their substrates; Lactate shuttle in glial cells; Glycolysis and gluconeogenesis; A network map of Macrophage-stimulating protein (MSP) signaling; Metabolic Epileptic Disorders"	"Pyruvate metabolism"	"19"	"0"	"5.7"	"8.2"	"9.1"	"19.6"	"7.3"	"6.6"	"13.3"	"14.9"	"15.7"	"48.0"	"70.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4T8"	"Carbonyl reductase family member 4 OS=Homo sapiens OX=9606 GN=CBR4 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"237"	"25.3"	"9.33"	"272.29"	"2.27"	"1"	"1"	"cell organization and biogenesis;other metabolic processes"	"mitochondrion;other cell component"	"other molecular function"	"Pf13561"	"84869"	"ENSG00000145439"	"CBR4"	"hsa:84869; Q8N4T8; Q8WTW8; Q96K93"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	"62.6"	"71.1"	"55.9"	"67.2"	"55.1"	"63.0"	"83.2"	"76.7"	"100.8"	"198.2"	"245.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P00374"	"Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2"	""	""	"6"	"1"	"1"	"1"	"187"	"21.4"	"7.42"	""	"2.27"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00186"	"1719"	"ENSG00000228716"	"DHFR"	"B4DDD2; hsa:1719; P00374; Q14130; Q6IRW8"	"Fluoropyrimidine activity; Folate metabolism; One-carbon metabolism; Retinoblastoma gene in cancer; Trans-sulfuration, one-carbon metabolism and related pathways; Ethanol effects on histone modifications"	"G1/S-Specific Transcription; Metabolism of folate and pterines; Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation"	"9"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P41212"	"Transcription factor ETV6 OS=Homo sapiens OX=9606 GN=ETV6 PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"452"	"53.0"	"7.43"	""	"2.27"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00178, Pf02198"	"2120"	"ENSG00000139083"	"ETV6"	"A3QVP6; A8K076; hsa:2120; P41212; Q9UMF6; Q9UMF7; Q9UMG0"	"Hematopoietic stem cell gene regulation by GABP alpha/beta complex; Exercise-induced circadian regulation"	"Signaling by FLT3 fusion proteins; Signaling by membrane-tethered fusions of PDGFRA or PDGFRB"	"4"	"0"	"26.6"	"18.0"	"29.5"	"42.2"	"21.6"	"23.3"	"55.9"	"58.2"	"84.3"	"252.0"	"459.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95352"	"Ubiquitin-like modifier-activating enzyme ATG7 OS=Homo sapiens OX=9606 GN=ATG7 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"703"	"77.9"	"6.24"	"298.94"	"2.26"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf00899, Pf16420"	"10533"	"ENSG00000197548"	"ATG7"	"B4E170; E9PB95; hsa:10533; O95352; Q7L8L0; Q9BWP2; Q9UFH4"	"Nanoparticle triggered autophagic cell death; Ferroptosis; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; Clock-controlled autophagy in bone metabolism; Primary ovarian insufficiency; Autophagy in pancreatic ductal adenocarcinoma"	"Neutrophil degranulation; Antigen processing: Ubiquitination & Proteasome degradation; Signaling by BRAF and RAF1 fusions; Macroautophagy"	"11"	"0"	"29.0"	"33.0"	"27.4"	"41.9"	"26.8"	"27.2"	"51.0"	"55.7"	"68.7"	"262.4"	"530.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5T1M5"	"FK506-binding protein 15 OS=Homo sapiens OX=9606 GN=FKBP15 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1219"	"133.5"	"5.20"	""	"2.26"	""	"1"	"transport"	"other membranes;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00254"	"23307"	"ENSG00000119321"	"FKBP15"	"hsa:23307; Q05DK8; Q5T1M2; Q5T1M5; Q6DD85; Q9Y4D0"	"TYROBP causal network in microglia"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y2Z0"	"Protein SGT1 homolog OS=Homo sapiens OX=9606 GN=SUGT1 PE=1 SV=3"	""	""	"6"	"1"	"1"	"1"	"365"	"41.0"	"5.16"	""	"2.26"	""	"1"	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf04969, Pf05002"	"10910"	"ENSG00000165416"	"SUGT1"	"A2A303; hsa:10910; Q5JAK5; Q5TAM6; Q6VXY6; Q9Y2Z0"	"Nucleotide-binding oligomerization domain (NOD) pathway"	"The NLRP3 inflammasome; Purinergic signaling in leishmaniasis infection"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NSE4"	"Isoleucine--tRNA ligase, mitochondrial OS=Homo sapiens OX=9606 GN=IARS2 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1012"	"113.7"	"7.20"	"257.38"	"2.26"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"nucleic acid binding activity;other molecular function"	"Pf00133, Pf06827, Pf08264"	"55699"	"ENSG00000067704"	"IARS2"	"B2RPG8; hsa:55699; Q1M2P9; Q6PI85; Q7L439; Q86WU9; Q96D91; Q9H9Q8; Q9NSE4; Q9NW42"	""	"Mitochondrial tRNA aminoacylation"	"1"	"0"	"11.1"	"13.0"	"10.5"	"20.4"	"8.4"	"7.2"	"18.7"	"25.2"	"38.7"	"88.1"	"153.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IYI6"	"Exocyst complex component 8 OS=Homo sapiens OX=9606 GN=EXOC8 PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"725"	"81.7"	"5.49"	"299.92"	"2.26"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf08700, Pf16528"	"149371"	"ENSG00000116903"	"EXOC8"	"B3KU33; hsa:149371; Q5TE82; Q8IYI6"	"RalA downstream regulated genes; Ciliary landscape"	"Insulin processing; Translocation of SLC2A4 (GLUT4) to the plasma membrane; VxPx cargo-targeting to cilium"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8N1G1"	"RNA exonuclease 1 homolog OS=Homo sapiens OX=9606 GN=REXO1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1221"	"131.4"	"8.95"	""	"2.26"	""	"1"	""	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf15870"	"57455"	"ENSG00000079313"	"REXO1"	"hsa:57455; Q8N1G1; Q9ULT2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJW0"	"Dynactin subunit 4 OS=Homo sapiens OX=9606 GN=DCTN4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"460"	"52.3"	"7.34"	"278.80"	"2.26"	"1"	"1"	""	"cytosol;cytoskeleton;nucleus;other cell component"	""	"Pf05502"	"51164"	"ENSG00000132912"	"DCTN4"	"B3KWW0; D3DQH0; E5RGT5; hsa:51164; Q8TAN8; Q9UJW0"	""	"HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; MHC class II antigen presentation; COPI-mediated anterograde transport; COPI-independent Golgi-to-ER retrograde traffic"	"4"	"0"	"10.3"	"10.1"	"11.8"	"24.4"	"12.9"	"5.6"	"29.3"	"36.3"	"61.8"	"240.2"	"366.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q147X3"	"N-alpha-acetyltransferase 30 OS=Homo sapiens OX=9606 GN=NAA30 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"362"	"39.3"	"5.52"	"252.01"	"2.26"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00583"	"122830"	"ENSG00000139977"	"NAA30"	"hsa:122830; Q0IIN2; Q147X3"	"Metapathway biotransformation Phase I and II"	"Retrograde transport at the Trans-Golgi-Network"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NDG6"	"ATP-dependent RNA helicase TDRD9 OS=Homo sapiens OX=9606 GN=TDRD9 PE=2 SV=3"	""	""	"1"	"1"	"1"	"1"	"1382"	"155.6"	"7.05"	""	"2.25"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00567, Pf04408"	"122402"	"ENSG00000156414"	"TDRD9"	"A1A4S7; hsa:122402; Q6ZU54; Q8N7T3; Q8N827; Q8N9V5; Q8NDG6; Q96AS9"	""	"PIWI-interacting RNA (piRNA) biogenesis"	"1"	"0"	"112.9"	"137.3"	"152.6"	"203.5"	"158.8"	"102.9"	"443.3"	"521.9"	"876.8"	"2256.4"	"2799.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7L590"	"Protein MCM10 homolog OS=Homo sapiens OX=9606 GN=MCM10 PE=1 SV=2"	"0.000"	""	"2"	"2"	"3"	"1"	"875"	"98.1"	"8.75"	"473.18"	"2.25"	"2"	"1"	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf09329, Pf09332"	"55388"	"ENSG00000065328"	"MCM10"	"A8K9I6; B7ZKZ8; hsa:55388; Q3MIR3; Q7L590; Q7LD55; Q96GX4; Q96NB6; Q9H0D7; Q9H3P9; Q9P177"	"Ciliary landscape; DNA replication"	"Activation of ATR in response to replication stress; Activation of the pre-replicative complex"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96F24"	"Nuclear receptor-binding factor 2 OS=Homo sapiens OX=9606 GN=NRBF2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"287"	"32.4"	"5.87"	"284.37"	"2.25"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"other membranes;nucleus;other cytoplasmic organelle;other cell component"	""	"Pf08961, Pf17169"	"29982"	"ENSG00000148572"	"NRBF2"	"A6PW36; B4DWS0; hsa:29982; Q86UR2; Q96F24; Q96NP6; Q9H0S9; Q9H2I2"	"Alzheimer's disease and miRNA effects; Alzheimer's disease"	""	"2"	"0"	"52.6"	"41.3"	"60.4"	"71.1"	"46.8"	"43.3"	"78.9"	"78.3"	"106.9"	"244.1"	"327.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75694"	"Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"1391"	"155.1"	"6.16"	"242.10"	"2.25"	"1"	"1"	"cell-cell signaling;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;nucleus"	"other molecular function"	"Pf03177, Pf08801"	"9631"	"ENSG00000113569"	"NUP155"	"hsa:9631; O75694; Q9UBE9; Q9UFL5"	""	"SUMOylation of DNA replication proteins; HCMV Late Events; HCMV Early Events; ISG15 antiviral mechanism; Transport of the SLBP independent Mature mRNA; Transport of the SLBP Dependant Mature mRNA; Transport of Mature mRNA Derived from an Intronless Transcript; Transport of Mature mRNA derived from an Intron-Containing Transcript; Rev-mediated nuclear export of HIV RNA; Transport of Ribonucleoproteins into the Host Nucleus; NS1 Mediated Effects on Host Pathways; Viral Messenger RNA Synthesis; NEP/NS2 Interacts with the Cellular Export Machinery; Regulation of Glucokinase by Glucokinase Regulatory Protein; Nuclear import of Rev protein; Vpr-mediated nuclear import of PICs; snRNP Assembly; SUMOylation of DNA damage response and repair proteins; SUMOylation of ubiquitinylation proteins; Nuclear Pore Complex (NPC) Disassembly; Regulation of HSF1-mediated heat shock response; SUMOylation of SUMOylation proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; Transcriptional regulation by small RNAs; Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC); tRNA processing in the nucleus; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Postmitotic nuclear pore complex (NPC) reformation"	"29"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43896"	"Kinesin-like protein KIF1C OS=Homo sapiens OX=9606 GN=KIF1C PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"1103"	"122.9"	"6.90"	"299.38"	"2.25"	"1"	"1"	"transport;other biological processes"	"cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00225, Pf00498, Pf16183"	"10749"	"ENSG00000129250"	"KIF1C"	"D3DTL6; hsa:10749; O43896; O75186; Q5U618"	""	"COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"2"	"0"	"9.0"	"8.6"	"13.5"	"18.0"	"12.3"	"8.1"	"12.1"	"14.8"	"22.6"	"32.7"	"49.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7Z401"	"C-myc promoter-binding protein OS=Homo sapiens OX=9606 GN=DENND4A PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1863"	"209.1"	"7.31"	""	"2.25"	""	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity;nucleic acid binding activity"	"Pf02141, Pf03455, Pf03456"	"10260"	"ENSG00000174485"	"DENND4A"	"E7EPL3; hsa:10260; Q14655; Q7Z401; Q86T77; Q8IVX2; Q8NB93"	""	"RAB GEFs exchange GTP for GDP on RABs"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96NL6"	"Sodium channel and clathrin linker 1 OS=Homo sapiens OX=9606 GN=SCLT1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"688"	"80.9"	"6.07"	"254.16"	"2.24"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	""	"132320"	"ENSG00000151466"	"SCLT1"	"A4QN04; hsa:132320; Q0VAH2; Q6P2M4; Q96NL6"	"Genes related to primary cilium development (based on CRISPR); Ciliopathies; Bardet-Biedl syndrome"	"Anchoring of the basal body to the plasma membrane"	"4"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q16222"	"UDP-N-acetylhexosamine pyrophosphorylase OS=Homo sapiens OX=9606 GN=UAP1 PE=1 SV=3"	"0.001"	""	"2"	"1"	"2"	"1"	"522"	"58.7"	"6.33"	"238.41"	"2.24"	"1"	"1"	"other metabolic processes"	"plasma membrane;other membranes;cytosol;nucleus"	"other molecular function"	"Pf01704"	"6675"	"ENSG00000117143"	"UAP1"	"B2R6R8; hsa:6675; Q16222; Q5VTA9; Q5VTB0; Q5VTB1; Q96GM2"	""	"Synthesis of UDP-N-acetyl-glucosamine"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2L9"	"Leucine-rich repeat and calponin homology domain-containing protein 1 OS=Homo sapiens OX=9606 GN=LRCH1 PE=1 SV=3"	"0.000"	""	"1"	"1"	"2"	"1"	"728"	"80.8"	"5.94"	"281.71"	"2.24"	"1"	"1"	"other biological processes"	"other cell component"	""	"Pf00307, Pf13855"	"23143"	"ENSG00000136141"	"LRCH1"	"B7ZLL5; F8W6F0; hsa:23143; Q17R43; Q2KHR1; Q5TBU9; Q7Z5F6; Q7Z5F7; Q9Y2L9"	""	""	"0"	"0"	"19.8"	"19.3"	"31.4"	"34.1"	"24.0"	"23.7"	"50.7"	"56.8"	"89.5"	"294.5"	"406.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GJ1"	"tRNA (uracil(54)-C(5))-methyltransferase homolog OS=Homo sapiens OX=9606 GN=TRMT2B PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"504"	"56.4"	"8.81"	"296.12"	"2.24"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf05958"	"79979"	"ENSG00000188917"	"TRMT2B"	"A6NDG5; A6NEI9; A6NMG6; hsa:79979; Q5JPF0; Q5JVY6; Q96GJ1; Q96HU7; Q96IH9; Q9H9K2"	""	""	"0"	"0"	"21.9"	"18.7"	"24.1"	"38.6"	"17.7"	"29.1"	"52.7"	"45.8"	"79.0"	"174.0"	"215.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N9R8"	"Protein SCAI OS=Homo sapiens OX=9606 GN=SCAI PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"606"	"70.4"	"8.60"	"271.00"	"2.24"	"1"	"1"	"other biological processes"	"other membranes;nucleus;other cell component"	"other molecular function"	"Pf12070"	"286205"	"ENSG00000173611"	"SCAI"	"hsa:286205; Q3SXZ1; Q3SXZ2; Q5T163; Q8N1I4; Q8N9R8"	""	"RHO GTPases Activate Formins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H8G2"	"Caspase activity and apoptosis inhibitor 1 OS=Homo sapiens OX=9606 GN=CAAP1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"361"	"38.3"	"4.72"	"245.55"	"2.24"	"1"	"1"	"other biological processes"	""	""	"Pf15335"	"79886"	"ENSG00000120159"	"CAAP1"	"B4DWT4; D3DRK4; hsa:79886; Q5VY32; Q6IPE6; Q96C59; Q9H8G2"	"Acute viral myocarditis"	""	"1"	"0"	"72.1"	"73.1"	"59.2"	"79.0"	"64.4"	"59.3"	"115.2"	"121.4"	"167.5"	"395.8"	"503.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P17028"	"Zinc finger protein 24 OS=Homo sapiens OX=9606 GN=ZNF24 PE=1 SV=4"	""	""	"2"	"1"	"1"	"1"	"368"	"42.1"	"6.21"	""	"2.24"	""	"1"	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096, Pf02023"	"7572"	"ENSG00000172466"	"ZNF24"	"hsa:7572; O14754; P17028; Q53YE4; Q6ICR5; Q8IZN4"	""	""	"0"	"0"	"136.8"	"144.4"	"135.2"	"153.4"	"125.5"	"137.9"	"180.2"	"173.8"	"231.5"	"389.2"	"460.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZU35"	"Capping protein inhibiting regulator of actin dynamics OS=Homo sapiens OX=9606 GN=CRACD PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"1233"	"136.7"	"5.60"	"251.87"	"2.24"	"1"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol"	""	"Pf15262"	"57482"	"ENSG00000109265"	"CRACD"	"hsa:57482; Q6ZU35; Q9NTE2; Q9NTP8; Q9ULK9"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H4B0"	"Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial OS=Homo sapiens OX=9606 GN=OSGEPL1 PE=2 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"414"	"45.1"	"8.56"	"230.96"	"2.24"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00814"	"64172"	"ENSG00000128694"	"OSGEPL1"	"hsa:64172; Q96EV9; Q96NH5; Q9H4B0"	""	""	"0"	"0"	"45.6"	"43.2"	"52.6"	"53.7"	"55.3"	"45.3"	"195.4"	"204.8"	"359.3"	"696.9"	"588.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BS16"	"Centromere protein K OS=Homo sapiens OX=9606 GN=CENPK PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"269"	"31.6"	"4.89"	"289.33"	"2.24"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;nucleus;other cell component"	""	"Pf11802"	"64105"	"ENSG00000123219"	"CENPK"	"hsa:64105; Q9BS16; Q9H4L0"	""	"Separation of Sister Chromatids; Resolution of Sister Chromatid Cohesion; RHO GTPases Activate Formins; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal; Deposition of new CENPA-containing nucleosomes at the centromere"	"7"	"0"	"12.5"	"11.8"	"11.7"	"22.0"	"8.4"	"13.2"	"22.0"	"23.5"	"37.8"	"63.0"	"125.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75380"	"NADH dehydrogenase [ubiquinone] iron-sulfur protein 6, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFS6 PE=1 SV=1"	""	""	"20"	"1"	"1"	"1"	"124"	"13.7"	"8.28"	""	"2.23"	""	"1"	"other metabolic processes;transport"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf10276"	"4726"	"ENSG00000145494"	"NDUFS6"	"hsa:4726; O75380"	"Electron transport chain: OXPHOS system in mitochondria; Nonalcoholic fatty liver disease; Oxidative phosphorylation"	"Complex I biogenesis"	"5"	"0"	"30.2"	"6.7"	"37.3"	"36.2"	"26.9"	"34.1"	"64.0"	"52.7"	"97.6"	"268.3"	"543.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99576"	"TSC22 domain family protein 3 OS=Homo sapiens OX=9606 GN=TSC22D3 PE=1 SV=2"	"0.000"	""	"7"	"1"	"2"	"1"	"134"	"14.8"	"4.54"	"331.55"	"2.23"	"1"	"1"	"stress response;other biological processes"	"cytosol;nucleus"	""	"Pf01166"	"1831"	"ENSG00000157514"	"TSC22D3"	"hsa:1831; Q5H9S3; Q5JRI9; Q5JRJ2; Q6FIH6; Q8NAI1; Q8WVB9; Q99576; Q9UBN5; Q9UG13"	"Glucocorticoid receptor pathway; Nuclear receptors meta-pathway"	"Stimuli-sensing channels"	"3"	"0"	"45.6"	"31.7"	"53.2"	"83.5"	"46.6"	"39.9"	"79.7"	"77.7"	"95.1"	"145.8"	"169.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7KZI7"	"Serine/threonine-protein kinase MARK2 OS=Homo sapiens OX=9606 GN=MARK2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"788"	"87.9"	"9.72"	""	"2.23"	""	"1"	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;mitochondrion;nucleus;other cell component"	"enzyme regulator activity;cytoskeletal activity;kinase activity;other molecular function"	"Pf00069, Pf00627, Pf02149"	"2011"	"ENSG00000072518"	"MARK2"	"hsa:2011; Q15449; Q15524; Q5XGA3; Q68A18; Q7KZI7; Q96HB3; Q96RG0"	"Microtubule cytoskeleton regulation; Complement system in neuronal development and plasticity; Neurogenesis regulation in the olfactory epithelium"	""	"3"	"0"	"91.4"	"34.6"	"66.7"	"174.0"	"67.1"	"88.9"	"63.4"	"139.1"	"165.6"	"263.2"	"275.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13049"	"E3 ubiquitin-protein ligase TRIM32 OS=Homo sapiens OX=9606 GN=TRIM32 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"653"	"71.9"	"6.98"	"279.30"	"2.23"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf01436, Pf13445"	"22954"	"ENSG00000119401"	"TRIM32"	"hsa:22954; Q13049; Q9NQP8"	"Ciliopathies; Bardet-Biedl syndrome"	"Antigen processing: Ubiquitination & Proteasome degradation; Regulation of innate immune responses to cytosolic DNA"	"4"	"0"	"17.0"	"20.7"	"14.2"	"20.4"	"17.2"	"11.2"	"29.0"	"38.8"	"45.4"	"132.9"	"146.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P16885"	"1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 OS=Homo sapiens OX=9606 GN=PLCG2 PE=1 SV=4"	""	""	"1"	"1"	"1"	"1"	"1265"	"147.8"	"6.64"	""	"2.22"	""	"1"	"cell-cell signaling;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"other molecular function"	"Pf00017, Pf00018, Pf00168, Pf00387, Pf00388"	"5336"	"ENSG00000197943"	"PLCG2"	"D3DUL3; hsa:5336; P16885; Q3ZTS2; Q59H45; Q969T5"	"Leptin signaling pathway; Glioblastoma signaling pathways; B cell receptor signaling pathway; Corticotropin-releasing hormone signaling pathway; Myometrial relaxation and contraction pathways; Microglia pathogen phagocytosis pathway; GPR40 pathway; Ras signaling; Non-small cell lung cancer; Non-genomic actions of 1,25 dihydroxyvitamin D3; Resistin as a regulator of inflammation; EGFR tyrosine kinase inhibitor resistance; GDNF signaling; 2q13 copy number variation syndrome; ErbB signaling pathway"	"Role of phospholipids in phagocytosis; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; FCGR3A-mediated IL10 synthesis; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; Generation of second messenger molecules; CLEC7A (Dectin-1) signaling; Toll Like Receptor 4 (TLR4) Cascade; GPVI-mediated activation cascade; DAP12 signaling; Synthesis of IP3 and IP4 in the cytosol; Signaling by CSF1 (M-CSF) in myeloid cells; Erythropoietin activates Phospholipase C gamma (PLCG); Dectin-2 family"	"30"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T51"	"RUN and FYVE domain-containing protein 1 OS=Homo sapiens OX=9606 GN=RUFY1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"708"	"79.8"	"5.74"	"251.77"	"2.22"	"1"	"1"	"transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01363, Pf02759"	"80230"	"ENSG00000176783; ENSG00000284260"	"RUFY1"	"hsa:80230; Q59FF3; Q71S93; Q96T51; Q9H6I3"	""	"Synthesis of PIPs at the plasma membrane"	"1"	"0"	"10.7"	"9.1"	"10.1"	"13.3"	"10.8"	"13.2"	"15.6"	"16.8"	"25.6"	"83.2"	"164.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BWD1"	"Acetyl-CoA acetyltransferase, cytosolic OS=Homo sapiens OX=9606 GN=ACAT2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"2"	"1"	"397"	"41.3"	"6.92"	"300.51"	"2.22"	"1"	"1"	"other metabolic processes"	"cytosol;mitochondrion;other cell component"	"other molecular function"	"Pf00108, Pf02803"	"39"	"ENSG00000120437"	"ACAT2"	"B7Z233; E1P5B1; hsa:39; Q16146; Q5TCL7; Q8TDM4; Q9BWD1"	"Mevalonate pathway; Cholesterol metabolism with Bloch and Kandutsch-Russell pathways; Cholesterol metabolism; Cholesterol biosynthesis pathway in hepatocytes; Enterocyte cholesterol metabolism"	"Cholesterol biosynthesis"	"6"	"0"	"8.3"	"15.4"	"15.5"	"31.3"	"8.3"	"8.4"	"13.6"	"13.5"	"12.0"	"35.5"	"54.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96FS4"	"Signal-induced proliferation-associated protein 1 OS=Homo sapiens OX=9606 GN=SIPA1 PE=1 SV=1"	"0.000"	""	"2"	"2"	"3"	"2"	"1042"	"112.1"	"6.60"	"506.99"	"2.22"	"2"	"1"	"cell organization and biogenesis;stress response;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"enzyme regulator activity"	"Pf00595, Pf02145"	"6494"	"ENSG00000213445"	"SIPA1"	"hsa:6494; O14518; O60484; O60618; Q2YD83; Q96FS4"	"MAPK cascade"	"Rap1 signalling"	"2"	"0"	"63.3"	"53.6"	"60.5"	"91.5"	"50.4"	"52.6"	"82.1"	"84.8"	"102.9"	"299.8"	"380.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N4C6"	"Ninein OS=Homo sapiens OX=9606 GN=NIN PE=1 SV=4"	"0.000"	""	"0"	"1"	"2"	"1"	"2090"	"243.1"	"5.03"	"281.49"	"2.22"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	""	"51199"	"ENSG00000100503"	"NIN"	"A6NDB8; B7WPA3; C9JSB6; C9JSG2; C9JXL2; hsa:51199; Q5BKU3; Q6P0P6; Q8N4C6; Q9BWU6; Q9C012; Q9C013; Q9C014; Q9H5I6; Q9HAT7; Q9HBY5; Q9HCK7; Q9UH61"	""	""	"0"	"0"	"6.2"	"6.2"	"4.6"	"6.0"	"2.8"	"3.8"	"8.4"	"11.4"	"10.0"	"29.8"	"48.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9ULU4"	"Protein kinase C-binding protein 1 OS=Homo sapiens OX=9606 GN=ZMYND8 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1186"	"131.6"	"7.20"	""	"2.22"	""	"1"	"cell organization and biogenesis;DNA metabolism;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf12064"	"23613"	"ENSG00000101040"	"ZMYND8"	"B3KVL2; B7Z2A8; B7Z3E0; B7Z680; B7ZM62; E1P5U5; F5H0X3; H7C0U2; hsa:23613; J3KPU3; Q13517; Q2HXV1; Q2HXV2; Q2HXV3; Q2HXV4; Q2HXV7; Q2HXV8; Q2HXV9; Q2HXW0; Q2HXW1; Q2HXW2; Q4JJ94; Q4JJ95; Q5TH09; Q5TH11; Q6MZM1; Q8WXC5; Q9H1F3; Q9H1F4; Q9H1F5; Q9H1L8; Q9H1L9; Q9H2G5; Q9NYN3; Q9UIX6; Q9ULU4"	""	""	"0"	"0"	"6.7"	"8.4"	"22.7"	"15.0"	"5.4"	"6.5"	"16.2"	"19.3"	"27.2"	"55.4"	"80.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UL03"	"Integrator complex subunit 6 OS=Homo sapiens OX=9606 GN=INTS6 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"887"	"100.3"	"8.62"	"246.78"	"2.21"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf13519, Pf15300"	"26512"	"ENSG00000102786"	"INTS6"	"hsa:26512; Q0P664; Q6PJP4; Q9UFK0; Q9UL03; Q9Y5M9"	""	"RNA polymerase II transcribes snRNA genes"	"1"	"0"	"19.5"	"20.9"	"11.6"	"30.0"	"16.6"	"17.3"	"36.7"	"45.6"	"59.2"	"234.8"	"316.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2N2"	"Rho GTPase-activating protein 28 OS=Homo sapiens OX=9606 GN=ARHGAP28 PE=1 SV=3"	"0.001"	""	"1"	"1"	"2"	"1"	"729"	"82.0"	"7.75"	"250.15"	"2.21"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf00620"	""	"ENSG00000088756"	"ARHGAP28"	"A8MQB7; A8MU88; Q6P160; Q8N4T3; Q9NW53; Q9P2N2"	""	"RHOA GTPase cycle"	"1"	"0"	"7.1"	"7.2"	"11.5"	"13.0"	"8.7"	"8.7"	"15.5"	"15.8"	"23.5"	"49.4"	"61.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95696"	"Bromodomain-containing protein 1 OS=Homo sapiens OX=9606 GN=BRD1 PE=1 SV=1"	"0.001"	""	"1"	"1"	"2"	"1"	"1058"	"119.4"	"8.60"	"251.75"	"2.21"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00439, Pf00855, Pf10513, Pf13831, Pf13832"	"23774"	"ENSG00000100425"	"BRD1"	"A6ZJA4; hsa:23774; O95696"	"Pathways affected in adenoid cystic carcinoma"	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4A5"	"Transformation/transcription domain-associated protein OS=Homo sapiens OX=9606 GN=TRRAP PE=1 SV=3"	"0.000"	""	"0"	"2"	"3"	"2"	"3859"	"437.3"	"8.19"	"490.03"	"2.21"	"2"	"1"	"cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf00454, Pf02259, Pf20175, Pf20206"	"8295"	"ENSG00000196367"	"TRRAP"	"A4D265; hsa:8295; O75218; Q9Y4A5; Q9Y631; Q9Y6H4"	"Rett syndrome causing genes"	"Ub-specific processing proteases; Formation of the beta-catenin:TCF transactivating complex; HATs acetylate histones"	"4"	"0"	"163.8"	"175.8"	"200.0"	"240.9"	"137.4"	"145.8"	"224.7"	"236.4"	"267.4"	"470.7"	"545.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96LR5"	"Ubiquitin-conjugating enzyme E2 E2 OS=Homo sapiens OX=9606 GN=UBE2E2 PE=1 SV=1"	""	""	"7"	"1"	"1"	"1"	"201"	"22.2"	"7.71"	""	"2.21"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"other molecular function"	"Pf00179"	"7325"	"ENSG00000182247"	"UBE2E2"	"hsa:7325; Q96LR5"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"74.8"	"28.9"	"94.5"	"100.5"	"85.3"	"69.9"	"132.6"	"121.6"	"158.2"	"292.6"	"491.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVR2"	"Integrator complex subunit 10 OS=Homo sapiens OX=9606 GN=INTS10 PE=1 SV=2"	"0.000"	""	"1"	"1"	"2"	"1"	"710"	"82.2"	"7.44"	"262.64"	"2.21"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	""	""	"55174"	"ENSG00000104613"	"INTS10"	"hsa:55174; Q6IA93; Q7L538; Q7L8C8; Q9H3W8; Q9NVR2"	"1p36 copy number variation syndrome"	"RNA polymerase II transcribes snRNA genes"	"2"	"0"	"91.7"	"106.2"	"95.0"	"110.1"	"105.0"	"77.4"	"180.8"	"193.0"	"211.3"	"564.8"	"829.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42338"	"Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform OS=Homo sapiens OX=9606 GN=PIK3CB PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"1070"	"122.7"	"7.09"	"305.99"	"2.21"	"1"	"1"	"cell adhesion;cell cycle OR cell proliferation;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00454, Pf00613, Pf00792, Pf00794, Pf02192"	"5291"	"ENSG00000051382"	"PIK3CB"	"D3DNF0; hsa:5291; P42338; Q24JU2"	"AMP-activated protein kinase signaling; MicroRNAs in cardiomyocyte hypertrophy; Prolactin signaling pathway; Alzheimer's disease and miRNA effects; Glioblastoma signaling pathways; Focal adhesion; PI3K-AKT-mTOR signaling pathway and therapeutic opportunities in prostate cancer; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; Microglia pathogen phagocytosis pathway; Endometrial cancer; PI3K-Akt signaling pathway; Ebola virus infection in host; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Pancreatic adenocarcinoma pathway; Nonalcoholic fatty liver disease; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; Neural crest cell migration during development; Neural crest cell migration in cancer; Translation inhibitors in chronically activated PDGFRA cells; Cancer immunotherapy by CTLA4 blockade; Measles virus infection; Small cell lung cancer; Hepatitis B infection; Head and neck squamous cell carcinoma; Melanoma; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; mBDNF and proBDNF regulation of GABA neurotransmission; Kisspeptin/kisspeptin receptor system in the ovary; Pleural mesothelioma; Regulation of actin cytoskeleton; Alzheimer's disease; GDNF signaling; G13 signaling pathway; ErbB signaling pathway; DNA damage response (only ATM dependent); Toll-like receptor signaling pathway"	"Downstream TCR signaling; Role of phospholipids in phagocytosis; Role of LAT2/NTAL/LAB on calcium mobilization; PIP3 activates AKT signaling; Synthesis of PIPs at the plasma membrane; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; RET signaling; Erythropoietin activates Phosphoinositide-3-kinase (PI3K); Interleukin receptor SHC signaling; Regulation of signaling by CBL; Nephrin family interactions; RAF/MAP kinase cascade; PI3K Cascade; GPVI-mediated activation cascade; Downstream signal transduction; PI3K/AKT activation; Signaling by ALK; Tie2 Signaling; DAP12 signaling; VEGFA-VEGFR2 Pathway; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Signaling by CSF1 (M-CSF) in myeloid cells"	"71"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P032"	"NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 OS=Homo sapiens OX=9606 GN=NDUFAF4 PE=1 SV=1"	"0.001"	""	"3"	"1"	"2"	"1"	"175"	"20.3"	"8.82"	"250.50"	"2.20"	"1"	"1"	"cell organization and biogenesis;stress response;other biological processes"	"other membranes;cytosol;mitochondrion"	"other molecular function"	"Pf06784"	"29078"	"ENSG00000123545"	"NDUFAF4"	"B2R4J5; hsa:29078; Q9P032"	""	"Complex I biogenesis"	"1"	"0"	"284.3"	"246.8"	"267.6"	"287.9"	"217.7"	"241.3"	"364.4"	"359.4"	"447.8"	"1194.7"	"1466.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P17707"	"S-adenosylmethionine decarboxylase proenzyme OS=Homo sapiens OX=9606 GN=AMD1 PE=1 SV=2"	"0.001"	""	"4"	"1"	"2"	"1"	"334"	"38.3"	"6.00"	"231.40"	"2.20"	"1"	"1"	"other metabolic processes"	"cytosol"	"other molecular function"	"Pf01536"	"262"	"ENSG00000123505"	"AMD1"	"E1P5F7; hsa:262; P17707; Q5VXN4; Q5VXN6; Q9BWK4"	"Methionine de novo and salvage pathway"	"Metabolism of polyamines"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96RW7"	"Hemicentin-1 OS=Homo sapiens OX=9606 GN=HMCN1 PE=1 SV=2"	""	""	"0"	"1"	"1"	"1"	"5635"	"613.0"	"6.49"	""	"2.20"	""	"1"	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"extracellular matrix;plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00090, Pf07474, Pf07645, Pf07679, Pf12662, Pf13927"	"83872"	"ENSG00000143341"	"HMCN1"	"A6NGE3; hsa:83872; Q5TYR7; Q96DN3; Q96DN8; Q96RW7; Q96SC3"	""	""	"0"	"0"	"35.3"	"29.1"	"45.5"	"47.2"	"34.2"	"32.7"	"77.8"	"68.6"	"93.9"	"205.1"	"288.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30260"	"Cell division cycle protein 27 homolog OS=Homo sapiens OX=9606 GN=CDC27 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"824"	"91.8"	"7.02"	"239.54"	"2.19"	"1"	"1"	"cell cycle OR cell proliferation;protein metabolism;other metabolic processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00515, Pf12895"	"996"	"ENSG00000004897"	"CDC27"	"G3V1C4; hsa:996; P30260; Q16349; Q96F35"	"Cell cycle; 2q21.1 copy number variation syndrome"	"Senescence-Associated Secretory Phenotype (SASP); Antigen processing: Ubiquitination & Proteasome degradation; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Separation of Sister Chromatids; CDK-mediated phosphorylation and removal of Cdc6; Autodegradation of Cdh1 by Cdh1:APC/C; Assembly of the pre-replicative complex; Inactivation of APC/C via direct inhibition of the APC/C complex; APC/C:Cdc20 mediated degradation of Cyclin B; Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase; Regulation of APC/C activators between G1/S and early anaphase; Phosphorylation of the APC/C; APC-Cdc20 mediated degradation of Nek2A; Transcriptional Regulation by VENTX; Aberrant regulation of mitotic exit in cancer due to RB1 defects"	"20"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92538"	"Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=GBF1 PE=1 SV=2"	"0.000"	""	"1"	"2"	"2"	"1"	"1859"	"206.3"	"5.73"	"337.75"	"2.18"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf01369, Pf12783, Pf16213"	"8729"	"ENSG00000107862"	"GBF1"	"hsa:8729; Q149P0; Q149P1; Q5VXX3; Q92538; Q96CK6; Q96HZ3; Q9H473"	""	"VxPx cargo-targeting to cilium; COPI-dependent Golgi-to-ER retrograde traffic; COPI-mediated anterograde transport; trans-Golgi Network Vesicle Budding"	"4"	"0"	"21.6"	"12.6"	"21.1"	"29.7"	"16.8"	"16.4"	"38.4"	"36.1"	"65.6"	"206.1"	"288.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P50995"	"Annexin A11 OS=Homo sapiens OX=9606 GN=ANXA11 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"505"	"54.4"	"7.65"	"250.17"	"2.18"	"1"	"1"	"cell cycle OR cell proliferation;transport;other biological processes"	"cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00191"	"311"	"ENSG00000122359"	"ANXA11"	"B4DVE7; hsa:311; P50995"	""	""	"0"	"0"	"130.4"	"97.4"	"172.0"	"197.2"	"134.9"	"102.3"	"230.4"	"247.5"	"299.1"	"487.1"	"550.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q12767"	"Transmembrane protein 94 OS=Homo sapiens OX=9606 GN=TMEM94 PE=1 SV=1"	"0.001"	""	"0"	"1"	"2"	"1"	"1356"	"151.1"	"6.44"	"230.53"	"2.18"	"1"	"1"	""	"other membranes"	""	""	"9772"	"ENSG00000177728"	"TMEM94"	"C9JL75; hsa:9772; O75536; Q12767; Q86XF1"	""	""	"0"	"0"	"45.9"	"32.2"	"46.2"	"50.7"	"50.1"	"83.2"	"348.2"	"386.6"	"449.7"	"426.9"	"423.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q06323"	"Proteasome activator complex subunit 1 OS=Homo sapiens OX=9606 GN=PSME1 PE=1 SV=1"	"0.000"	""	"8"	"2"	"3"	"2"	"249"	"28.7"	"6.02"	"751.28"	"2.18"	"2"	"1"	"other biological processes"	"cytosol;nucleus;other cell component"	"enzyme regulator activity"	"Pf02251, Pf02252"	"5720"	"ENSG00000092010; ENSG00000284916"	"PSME1"	"A6NJG9; H0YNE3; hsa:5720; Q06323; Q6IBM2; Q9UEF4"	"Proteasome degradation"	"FCERI mediated NF-kB activation; Downstream TCR signaling; Antigen processing: Ubiquitination & Proteasome degradation; Activation of NF-kappaB in B cells; Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha; ER-Phagosome pathway; Cross-presentation of soluble exogenous antigens (endosomes); SCF-beta-TrCP mediated degradation of Emi1; APC/C:Cdc20 mediated degradation of Securin; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1; Cdc20:Phospho-APC/C mediated degradation of Cyclin A; Vpu mediated degradation of CD4; Vif-mediated degradation of APOBEC3G; Degradation of beta-catenin by the destruction complex; Regulation of activated PAK-2p34 by proteasome mediated degradation; Separation of Sister Chromatids; Autodegradation of the E3 ubiquitin ligase COP1; Regulation of ornithine decarboxylase (ODC); ABC-family proteins mediated transport; AUF1 (hnRNP D0) binds and destabilizes mRNA; Asymmetric localization of PCP proteins; Degradation of AXIN; Degradation of DVL; Hedgehog ligand biogenesis; Hh mutants are degraded by ERAD; Dectin-1 mediated noncanonical NF-kB signaling; Degradation of GLI1 by the proteasome; Degradation of GLI2 by the proteasome; GLI3 is processed to GLI3R by the proteasome; Hedgehog 'on' state; Regulation of RAS by GAPs; NIK-->noncanonical NF-kB signaling; Defective CFTR causes cystic fibrosis; MAPK6/MAPK4 signaling; UCH proteinases; Ub-specific processing proteases; Orc1 removal from chromatin; CDK-mediated phosphorylation and removal of Cdc6; G2/M Checkpoints; Ubiquitin Mediated Degradation of Phosphorylated Cdc25A; Ubiquitin-dependent degradation of Cyclin D; The role of GTSE1 in G2/M progression after G2 checkpoint; FBXL7 down-regulates AURKA during mitotic entry and in early mitosis; RUNX1 regulates transcription of genes involved in differentiation of HSCs; Regulation of RUNX2 expression and activity; Regulation of PTEN stability and activity; Neddylation; Regulation of expression of SLITs and ROBOs; Interleukin-1 signaling; KEAP1-NFE2L2 pathway; Somitogenesis; Autodegradation of Cdh1 by Cdh1:APC/C; SCF(Skp2)-mediated degradation of p27/p21; Assembly of the pre-replicative complex; Regulation of RUNX3 expression and activity; Negative regulation of NOTCH4 signaling; GSK3B and BTRC:CUL1-mediated-degradation of NFE2L2"	"60"	"0"	"142.0"	"120.7"	"142.2"	"204.3"	"125.4"	"110.7"	"186.0"	"206.1"	"247.8"	"631.1"	"745.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P61927"	"60S ribosomal protein L37 OS=Homo sapiens OX=9606 GN=RPL37 PE=1 SV=2"	"0.001"	""	"6"	"1"	"2"	"1"	"97"	"11.1"	"11.74"	"234.03"	"2.18"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01907"	"6167"	"ENSG00000145592"	"RPL37"	"B2R4H2; hsa:6167; P02403; P61927; Q6IBB4; Q99883"	"Cytoplasmic ribosomal proteins"	"Regulation of expression of SLITs and ROBOs; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC); L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Major pathway of rRNA processing in the nucleolus and cytosol; SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Response of EIF2AK4 (GCN2) to amino acid deficiency; Peptide chain elongation; Selenocysteine synthesis"	"14"	"0"	"135.7"	"208.7"	"129.0"	"183.5"	"143.5"	"124.4"	"204.4"	"235.6"	"254.6"	"468.5"	"638.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UG01"	"Intraflagellar transport protein 172 homolog OS=Homo sapiens OX=9606 GN=IFT172 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1749"	"197.5"	"6.13"	""	"2.18"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"cytoskeleton;other cell component"	""	"Pf00400"	"26160"	"ENSG00000138002"	"IFT172"	"A5PKZ0; B2RNU5; hsa:26160; Q86X44; Q96HW4; Q9UFJ9; Q9UG01; Q9ULP1"	"Ciliary landscape; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Alstrom syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport; Hedgehog 'off' state"	"7"	"0"	"181.3"	"114.6"	"230.8"	"249.2"	"157.1"	"203.9"	"227.0"	"199.7"	"241.7"	"413.2"	"708.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9C0C9"	"(E3-independent) E2 ubiquitin-conjugating enzyme OS=Homo sapiens OX=9606 GN=UBE2O PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1292"	"141.2"	"5.12"	""	"2.18"	""	"1"	"protein metabolism;other metabolic processes;transport;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"63893"	"ENSG00000175931"	"UBE2O"	"A6NDU5; hsa:63893; Q69YP4; Q6PIZ2; Q86UA4; Q8N425; Q8TBN1; Q9BSW1; Q9C0C9; Q9H6E6; Q9H7E4; Q9H9B2"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"93.4"	"82.4"	"99.6"	"125.3"	"93.5"	"87.6"	"140.6"	"146.9"	"170.7"	"324.1"	"455.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96MN5"	"Transcription elongation factor A N-terminal and central domain-containing protein 2 OS=Homo sapiens OX=9606 GN=TCEANC2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"208"	"24.1"	"10.05"	"286.76"	"2.17"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	""	"Pf08711"	"127428"	"ENSG00000116205"	"TCEANC2"	"hsa:127428; Q5T702; Q8N8N2; Q96MN5"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54277"	"PMS1 protein homolog 1 OS=Homo sapiens OX=9606 GN=PMS1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"2"	"1"	"932"	"105.8"	"6.67"	"297.61"	"2.17"	"1"	"1"	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf01119, Pf02518"	"5378"	"ENSG00000064933"	"PMS1"	"D3DPI1; hsa:5378; P54277; Q4VAL4; Q5FBZ3; Q5FBZ6; Q5FBZ8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NEP4"	"Uncharacterized protein C17orf47 OS=Homo sapiens OX=9606 GN=C17orf47 PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"570"	"63.1"	"9.20"	""	"2.17"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"29.6"	"18.5"	"50.6"	"53.0"	"37.8"	"37.4"	"56.3"	"59.1"	"79.8"	"187.7"	"301.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"B2RTY4"	"Unconventional myosin-IXa OS=Homo sapiens OX=9606 GN=MYO9A PE=1 SV=2"	"0.000"	""	"0"	"1"	"2"	"1"	"2548"	"292.5"	"8.88"	"271.60"	"2.17"	"1"	"1"	"cell organization and biogenesis;signal transduction;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"enzyme regulator activity;cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf00620, Pf00788"	"4649"	"ENSG00000066933"	"MYO9A"	"B0I1T5; B2RTY4; C9IYB3; C9JA86; hsa:4649; Q14787; Q3YLD7; Q3YLD8; Q6P986; Q9H8T5; Q9NTG2; Q9NUY2; Q9UEP3; Q9UNJ2"	""	"RHOA GTPase cycle; RHOB GTPase cycle; RHOV GTPase cycle"	"3"	"0"	"22.7"	"18.2"	"23.3"	"24.8"	"23.1"	"14.7"	"24.8"	"32.6"	"35.4"	"66.0"	"72.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P63272"	"Transcription elongation factor SPT4 OS=Homo sapiens OX=9606 GN=SUPT4H1 PE=1 SV=1"	""	""	"14"	"1"	"1"	"1"	"117"	"13.2"	"8.06"	""	"2.17"	""	"1"	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus"	"other molecular function"	"Pf06093"	"6827"	"ENSG00000213246"	"SUPT4H1"	"B2R4X8; D3DTZ4; hsa:6827; P63272; Q16550; Q62387; Q6ZP89"	"Initiation of transcription and translation elongation at the HIV-1 LTR"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes"	"16"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SU4"	"Oxysterol-binding protein-related protein 9 OS=Homo sapiens OX=9606 GN=OSBPL9 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"736"	"83.1"	"6.18"	"439.73"	"2.17"	"1"	"1"	"other metabolic processes;transport"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00169, Pf01237"	"114883"	"ENSG00000117859"	"OSBPL9"	"B1AKJ8; B3KPQ4; D3DQ31; hsa:114883; Q5TFC0; Q6IA67; Q86YQ3; Q8NB17; Q8TAS8; Q96SK4; Q96SU4; Q9H9X2"	""	"Synthesis of bile acids and bile salts"	"1"	"0"	"60.2"	"55.9"	"78.7"	"79.2"	"62.9"	"62.1"	"88.9"	"104.0"	"138.3"	"351.3"	"481.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q14457"	"Beclin-1 OS=Homo sapiens OX=9606 GN=BECN1 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"450"	"51.9"	"4.89"	""	"2.17"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf04111, Pf15285, Pf17675"	"8678"	"ENSG00000126581"	"BECN1"	"B2R6N7; hsa:8678; O75595; Q14457; Q9UNA8"	"Alzheimer's disease and miRNA effects; Nanoparticle triggered autophagic cell death; Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway; Autophagy; 7q11.23 copy number variation syndrome; Pleural mesothelioma; Alzheimer's disease; Clock-controlled autophagy in bone metabolism; Autophagy in pancreatic ductal adenocarcinoma"	"Macroautophagy; SARS-CoV-2 activates/modulates innate and adaptive immune responses; Ub-specific processing proteases; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Translation of Replicase and Assembly of the Replication Transcription Complex; Translation of Replicase and Assembly of the Replication Transcription Complex"	"15"	"0"	"76.2"	"22.5"	"340.7"	"24.3"	"15.5"	"22.0"	"87.9"	"63.0"	"67.4"	"94.5"	"193.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y320"	"Thioredoxin-related transmembrane protein 2 OS=Homo sapiens OX=9606 GN=TMX2 PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"296"	"34.0"	"8.69"	""	"2.17"	""	"1"	"developmental processes"	"other membranes;mitochondrion;ER/Golgi;other cell component"	"other molecular function"	"Pf00085"	"51075"	"ENSG00000213593"	"TMX2"	"B7Z4R4; hsa:51075; Q53G73; Q561W0; Q5J7Q7; Q8NBP9; Q9H3L1; Q9Y320"	""	""	"0"	"0"	"16.4"	"14.7"	"12.8"	"12.6"	"10.4"	"17.9"	"29.5"	"35.0"	"39.7"	"93.0"	"147.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15573"	"TATA box-binding protein-associated factor RNA polymerase I subunit A OS=Homo sapiens OX=9606 GN=TAF1A PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"450"	"52.6"	"9.10"	""	"2.17"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytoskeleton;nucleus"	"nucleic acid binding activity"	"Pf14929"	"9015"	"ENSG00000143498"	"TAF1A"	"B2RDZ8; D3DTB7; hsa:9015; Q15573; Q9NWA1"	""	"B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; SIRT1 negatively regulates rRNA expression"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4I1"	"Unconventional myosin-Va OS=Homo sapiens OX=9606 GN=MYO5A PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1855"	"215.3"	"8.48"	"256.47"	"2.16"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"other membranes;cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf00612, Pf01843"	"4644"	"ENSG00000197535"	"MYO5A"	"A8MZC5; hsa:4644; O60653; Q07902; Q16249; Q9UE30; Q9UE31; Q9Y4I1"	"Joubert syndrome; 2q37 copy number variation syndrome"	"Regulation of actin dynamics for phagocytic cup formation; FCGR3A-mediated phagocytosis; Translocation of SLC2A4 (GLUT4) to the plasma membrane; Insulin processing"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UQ4"	"ATP-binding cassette sub-family A member 13 OS=Homo sapiens OX=9606 GN=ABCA13 PE=2 SV=3"	"0.001"	""	"1"	"2"	"3"	"1"	"5058"	"575.8"	"6.46"	"253.74"	"2.16"	"1"	"1"	"transport;other biological processes"	"plasma membrane;other membranes;other cytoplasmic organelle;other cell component"	"transporter activity;other molecular function"	"Pf00005, Pf12698"	"154664"	"ENSG00000179869"	"ABCA13"	"hsa:154664; K9LC76; K9LC79; K9LCX7; K9LDK8; K9LDY4; Q6ZTT7; Q86UQ4; Q86WI2; Q8N248"	""	"Neutrophil degranulation"	"1"	"0"	"182.3"	"47.9"	"306.5"	"223.9"	"175.1"	"180.2"	"262.8"	"195.0"	"310.5"	"619.4"	"1312.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8IUX1"	"Complex I assembly factor TMEM126B, mitochondrial OS=Homo sapiens OX=9606 GN=TMEM126B PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"230"	"25.9"	"8.81"	""	"2.16"	""	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;mitochondrion"	""	"Pf07114"	"55863"	"ENSG00000171204"	"TMEM126B"	"A8K535; A8MSS0; hsa:55863; Q32Q09; Q8IUX1; Q8WVU3; Q96EP3; Q9NZ29"	""	"Complex I biogenesis"	"1"	"0"	"28.4"	"17.6"	"31.1"	"39.8"	"27.3"	"37.0"	"159.3"	"179.8"	"400.2"	"514.1"	"588.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UNA4"	"DNA polymerase iota OS=Homo sapiens OX=9606 GN=POLI PE=1 SV=3"	""	""	"3"	"1"	"1"	"1"	"740"	"83.0"	"6.07"	""	"2.16"	""	"1"	"DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00817, Pf11799"	"11201"	"ENSG00000101751"	"POLI"	"hsa:11201; Q8N590; Q9H0S1; Q9NYH6; Q9UNA4"	"DNA repair pathways, full network"	"Termination of translesion DNA synthesis; Translesion synthesis by POLI"	"3"	"0"	"11.8"	"5.8"	"14.9"	"18.0"	"16.5"	"27.9"	"173.6"	"155.9"	"298.6"	"472.2"	"1196.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08945"	"FACT complex subunit SSRP1 OS=Homo sapiens OX=9606 GN=SSRP1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"2"	"1"	"709"	"81.0"	"6.87"	"460.20"	"2.16"	"1"	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00505, Pf03531, Pf08512, Pf17292"	"6749"	"ENSG00000149136"	"SSRP1"	"hsa:6749; Q08945; Q5BJG8"	""	"Regulation of TP53 Activity through Phosphorylation; Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BYX2"	"TBC1 domain family member 2A OS=Homo sapiens OX=9606 GN=TBC1D2 PE=1 SV=3"	""	""	"2"	"1"	"1"	"1"	"928"	"105.3"	"6.58"	""	"2.16"	""	"1"	"other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf00566"	"55357"	"ENSG00000095383"	"TBC1D2"	"B3KWD1; B4DQ05; B9A6J7; hsa:55357; Q59EU0; Q5TBQ5; Q6IPC7; Q7L1K8; Q8WYT1; Q9BYX2; Q9H6A2; Q9NSH4"	""	"TBC/RABGAPs"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9NR96"	"Toll-like receptor 9 OS=Homo sapiens OX=9606 GN=TLR9 PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"1032"	"115.8"	"8.19"	""	"2.15"	""	"1"	"protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;nucleic acid binding activity;other molecular function"	"Pf01582, Pf13516, Pf13855, Pf18837"	"54106"	"ENSG00000239732"	"TLR9"	"B3Y661; D1CS56; hsa:54106; Q6UVZ2; Q9HD68; Q9HD69; Q9HD70; Q9NR96; Q9NYC2; Q9NYC3"	"Toll-like receptor signaling related to MyD88; MYD88 distinct input-output pathway; Measles virus infection; Burn wound healing; Genetic causes of porto-sinusoidal vascular disease; Induction of autophagy and toll-like receptor signaling pathways by graphene oxide ; Toll-like receptor signaling pathway"	"Potential therapeutics for SARS; TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling; PI3K Cascade; Trafficking and processing of endosomal TLR; TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation"	"14"	"0"	"31.5"	"22.7"	"32.0"	"38.5"	"24.5"	"27.5"	"68.4"	"94.4"	"140.2"	"398.8"	"722.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14807"	"Kinesin-like protein KIF22 OS=Homo sapiens OX=9606 GN=KIF22 PE=1 SV=5"	"0.000"	""	"2"	"1"	"2"	"1"	"665"	"73.2"	"9.45"	"337.31"	"2.15"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00225, Pf12836"	"3835"	"ENSG00000079616"	"KIF22"	"B2R5M0; B7Z265; hsa:3835; O60845; O94814; Q14807; Q53F58; Q9BT46"	"16p11.2 proximal deletion syndrome"	"MHC class II antigen presentation; COPI-dependent Golgi-to-ER retrograde traffic; Kinesins"	"4"	"0"	"24.7"	"23.4"	"34.5"	"48.8"	"29.7"	"25.5"	"58.3"	"55.6"	"84.6"	"209.4"	"293.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P08243"	"Asparagine synthetase [glutamine-hydrolyzing] OS=Homo sapiens OX=9606 GN=ASNS PE=1 SV=4"	"0.001"	""	"1"	"1"	"2"	"1"	"561"	"64.3"	"6.86"	"252.41"	"2.15"	"1"	"1"	"other metabolic processes;stress response;other biological processes"	"cytosol"	"other molecular function"	"Pf00733, Pf13537"	"440"	"ENSG00000070669"	"ASNS"	"A4D1I8; B4DXZ1; B7ZAA9; D6W5R3; E9PCI3; E9PCX6; hsa:440; P08184; P08243; Q15666; Q549T9; Q96HD0"	"Photodynamic therapy-induced unfolded protein response; Amino acid metabolism"	"Aspartate and asparagine metabolism; Response of EIF2AK1 (HRI) to heme deficiency; ATF4 activates genes in response to endoplasmic reticulum  stress; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"6"	"0"	"102.7"	"102.8"	"130.0"	"208.3"	"65.0"	"100.7"	"145.3"	"143.4"	"171.2"	"490.8"	"768.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UET6"	"Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase OS=Homo sapiens OX=9606 GN=FTSJ1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"2"	"1"	"329"	"36.1"	"5.69"	"250.92"	"2.15"	"1"	"1"	"protein metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf01728"	"24140"	"ENSG00000068438"	"FTSJ1"	"B2RCJ0; hsa:24140; O75670; Q9UET6"	""	"tRNA modification in the nucleus and cytosol"	"1"	"0"	"88.4"	"95.5"	"129.7"	"161.8"	"100.9"	"92.3"	"190.5"	"189.9"	"269.6"	"699.2"	"986.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96PY5"	"Formin-like protein 2 OS=Homo sapiens OX=9606 GN=FMNL2 PE=1 SV=3"	"0.000"	""	"2"	"2"	"3"	"1"	"1086"	"123.2"	"7.40"	"487.68"	"2.15"	"2"	"1"	"cell organization and biogenesis;other biological processes"	"cytosol"	"cytoskeletal activity;other molecular function"	"Pf02181, Pf06367, Pf06371"	"114793"	"ENSG00000157827"	"FMNL2"	"B2RZH5; hsa:114793; Q14CC9; Q4ZG52; Q8N3E0; Q96PY5"	"Epithelial to mesenchymal transition in colorectal cancer"	"RHO GTPases Activate Formins; CDC42 GTPase cycle; RHOC GTPase cycle"	"4"	"1"	"35.8"	"24.6"	"44.8"	"54.4"	"32.3"	"28.0"	"54.8"	"65.0"	"43.5"	"307.1"	"2292.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HCD6"	"Protein TANC2 OS=Homo sapiens OX=9606 GN=TANC2 PE=1 SV=3"	"0.000"	""	"0"	"1"	"2"	"1"	"1990"	"219.5"	"8.07"	"320.55"	"2.14"	"1"	"1"	"transport;other biological processes"	"other cell component"	""	"Pf12796, Pf13181"	"26115"	"ENSG00000170921"	"TANC2"	"hsa:26115; Q9HAC3; Q9HCD6; Q9NW88; Q9NXY9; Q9ULS2"	""	""	"0"	"0"	"18.0"	"17.4"	"31.2"	"43.5"	"21.9"	"19.8"	"45.8"	"50.6"	"70.1"	"194.9"	"264.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"G2XKQ0"	"Small ubiquitin-related modifier 5 OS=Homo sapiens OX=9606 GN=SUMO1P1 PE=1 SV=2"	""	""	"7"	"1"	"1"	"1"	"101"	"11.5"	"5.52"	""	"2.14"	""	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"nucleus"	"other molecular function"	"Pf11976"	""	""	"SUMO1P1"	"G2XKQ0"	""	""	"0"	"0"	"160.7"	"144.5"	"160.6"	"216.3"	"151.1"	"139.3"	"198.3"	"202.0"	"210.7"	"333.1"	"445.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2P8"	"RNA 3'-terminal phosphate cyclase-like protein OS=Homo sapiens OX=9606 GN=RCL1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"373"	"40.8"	"9.26"	"380.03"	"2.14"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf01137, Pf05189"	"10171"	"ENSG00000120158"	"RCL1"	"D3DRI2; hsa:10171; Q5VYW9; Q5VZU1; Q9H9D0; Q9NY00; Q9P044; Q9Y2P8"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"2"	"0"	"12.9"	"12.8"	"15.0"	"20.1"	"14.9"	"10.2"	"17.0"	"19.2"	"31.4"	"50.3"	"79.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NBZ0"	"INO80 complex subunit E OS=Homo sapiens OX=9606 GN=INO80E PE=1 SV=1"	""	""	"2"	"1"	"1"	"1"	"244"	"26.5"	"8.34"	""	"2.14"	""	"1"	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus"	""	""	"283899"	"ENSG00000169592"	"INO80E"	"hsa:283899; Q6Y2K3; Q8NBZ0"	"16p11.2 proximal deletion syndrome"	"UCH proteinases; DNA Damage Recognition in GG-NER"	"3"	"0"	"114.5"	"89.8"	"120.8"	"182.9"	"102.6"	"78.6"	"147.6"	"146.1"	"159.5"	"305.7"	"369.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P98082"	"Disabled homolog 2 OS=Homo sapiens OX=9606 GN=DAB2 PE=1 SV=3"	"0.000"	""	"3"	"2"	"4"	"2"	"770"	"82.4"	"5.53"	"487.98"	"2.14"	"2"	"1"	"cell-cell signaling;cell organization and biogenesis;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00640"	"1601"	"ENSG00000153071"	"DAB2"	"A6NES5; hsa:1601; P98082; Q13598; Q9BTY0; Q9UK04"	"Endoderm differentiation"	"Cargo recognition for clathrin-mediated endocytosis; Formation of annular gap junctions"	"5"	"0"	"42.2"	"29.8"	"53.7"	"45.1"	"33.3"	"38.9"	"78.8"	"78.3"	"116.6"	"188.3"	"195.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P38398"	"Breast cancer type 1 susceptibility protein OS=Homo sapiens OX=9606 GN=BRCA1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"2"	"1"	"1863"	"207.6"	"5.41"	"253.94"	"2.14"	"1"	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;nucleic acid binding activity;other molecular function"	"Pf00097, Pf00533, Pf12820"	"672"	"ENSG00000012048"	"BRCA1"	"E9PFZ0; hsa:672; O15129; P38398; Q1RMC1; Q3LRJ0; Q3LRJ6; Q6IN79; Q7KYU9"	"Androgen receptor signaling pathway; miRNA regulation of DNA damage response; Glioblastoma signaling pathways; Hepatitis C and hepatocellular carcinoma; Pathways affected in adenoid cystic carcinoma; PI3K-Akt signaling pathway; Breast cancer pathway; DNA repair pathways, full network; Pleural mesothelioma; Nucleotide excision repair in xeroderma pigmentosum ; SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome; Primary ovarian insufficiency; 5q35 copy number variation; DNA damage response"	"Meiotic synapsis; Resolution of D-loop Structures through Holliday Junction Intermediates; Neddylation; KEAP1-NFE2L2 pathway; SUMOylation of DNA damage response and repair proteins; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; TP53 Regulates Transcription of DNA Repair Genes; Regulation of TP53 Activity through Phosphorylation; Transcriptional Regulation by E2F6; Metalloprotease DUBs; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; Meiotic recombination; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Nonhomologous End-Joining (NHEJ); Defective DNA double strand break response due to BRCA1 loss of function; Defective DNA double strand break response due to BARD1 loss of function"	"40"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NEE6"	"Dynein regulatory complex subunit 6 OS=Homo sapiens OX=9606 GN=FBXL13 PE=2 SV=3"	"0.001"	""	"1"	"1"	"4"	"1"	"735"	"83.9"	"8.72"	"232.70"	"2.14"	"1"	"1"	"protein metabolism;other metabolic processes"	"cytosol;cytoskeleton;other cell component"	""	"Pf13516"	"222235"	"ENSG00000161040"	"FBXL13"	"C9J565; C9J566; hsa:222235; Q6UVW7; Q6UVW8; Q75MN5; Q86UJ5; Q8N7Y4; Q8NEE6; Q8TCL2; Q8WUF9; Q8WUG0"	""	"Antigen processing: Ubiquitination & Proteasome degradation; Neddylation"	"2"	"0"	"5.3"	"2.3"	"12.1"	"13.2"	"6.6"	"7.9"	"34.1"	"30.3"	"66.6"	"96.0"	"166.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P48200"	"Iron-responsive element-binding protein 2 OS=Homo sapiens OX=9606 GN=IREB2 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"963"	"105.0"	"7.05"	"284.03"	"2.13"	"1"	"1"	"other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;mitochondrion;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00330, Pf00694"	"3658"	"ENSG00000136381"	"IREB2"	"A0A0A6YY96; A8KAC7; E1CJT9; H0YKU0; hsa:3658; P48200; Q13095; Q1HE21; Q59FQ7; Q8WVK6; Q9UF17"	"Iron metabolism in placenta; Ferroptosis"	"Iron uptake and transport"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O15055"	"Period circadian protein homolog 2 OS=Homo sapiens OX=9606 GN=PER2 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1255"	"136.5"	"6.47"	""	"2.13"	""	"1"	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf08447, Pf12114"	"8864"	"ENSG00000132326"	"PER2"	"A2I2P7; hsa:8864; O15055; Q4ZG49; Q6DT41; Q9UQ45"	"Melatonin metabolism and effects; Exercise-induced circadian regulation; Orexin receptor pathway; 2q37 copy number variation syndrome"	"Circadian Clock"	"5"	"0"	"0.0"	"2.5"	"3.8"	"55.4"	"67.3"	"2.7"	"26.3"	"14.5"	"13.1"	"16.8"	"42.8"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P50402"	"Emerin OS=Homo sapiens OX=9606 GN=EMD PE=1 SV=1"	""	""	"3"	"1"	"1"	"1"	"254"	"29.0"	"5.50"	""	"2.13"	""	"1"	"cell organization and biogenesis;other biological processes"	"other membranes;cytosol;cytoskeleton;ER/Golgi;nucleus;other cell component"	"cytoskeletal activity"	"Pf03020"	"2010"	"ENSG00000102119"	"EMD"	"hsa:2010; P50402; Q6FI02"	"Arrhythmogenic right ventricular cardiomyopathy; Envelope proteins and their potential roles in EDMD physiopathology; Influence of laminopathies on Wnt signaling"	"Initiation of Nuclear Envelope (NE) Reformation; Depolymerization of the Nuclear Lamina; RHOG GTPase cycle; RAC1 GTPase cycle; RAC2 GTPase cycle; RAC3 GTPase cycle; RHOD GTPase cycle; Insertion of tail-anchored proteins into the endoplasmic reticulum membrane"	"12"	"0"	"88.4"	"97.7"	"108.5"	"114.9"	"80.1"	"85.6"	"122.4"	"138.3"	"158.3"	"318.1"	"417.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q13905"	"Rap guanine nucleotide exchange factor 1 OS=Homo sapiens OX=9606 GN=RAPGEF1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1077"	"120.5"	"5.92"	""	"2.12"	""	"1"	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00617, Pf00618"	"2889"	"ENSG00000107263"	"RAPGEF1"	"hsa:2889; Q13905; Q5JUE4; Q68DL3; Q8IV73"	"Integrin-mediated cell adhesion; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; IL-3 signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Insulin signaling; Interferon type I signaling pathways"	"RAC3 GTPase cycle; Regulation of signaling by CBL; Downstream signal transduction; Erythropoietin activates RAS; Frs2-mediated activation; MET activates RAP1 and RAC1"	"16"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q15349"	"Ribosomal protein S6 kinase alpha-2 OS=Homo sapiens OX=9606 GN=RPS6KA2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"733"	"83.2"	"8.68"	""	"2.12"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069, Pf00433"	"6196"	"ENSG00000071242"	"RPS6KA2"	"B3KTK9; hsa:6196; Q15349; Q15419; Q59GJ3; Q5TI68; Q96J38; Q9UJN5"	"Prolactin signaling pathway; Angiopoietin-like protein 8 regulatory pathway; Thermogenesis; EGF/EGFR signaling pathway; Translation inhibitors in chronically activated PDGFRA cells; Cytoplasmic ribosomal proteins; Insulin signaling; Host-pathogen interaction of human coronaviruses - MAPK signaling"	"Senescence-Associated Secretory Phenotype (SASP); Recycling pathway of L1; RSK activation; ERK/MAPK targets; CREB phosphorylation; Gastrin-CREB signalling pathway via PKC and MAPK"	"15"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8WZ42"	"Titin OS=Homo sapiens OX=9606 GN=TTN PE=1 SV=4"	""	""	"0"	"1"	"1"	"1"	"34350"	"3813.7"	"6.35"	""	"2.12"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;cytosol;cytoskeleton;nucleus"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00041, Pf00069, Pf02818, Pf07679, Pf09042, Pf18362"	"7273"	"ENSG00000155657"	"TTN"	"A6NKB1; E7EQE6; E7ET18; hsa:7273; K7ENY1; Q10465; Q10466; Q15598; Q2XUS3; Q32Q60; Q4U1Z6; Q4ZG20; Q6NSG0; Q6PDB1; Q6PJP0; Q7KYM2; Q7KYN4; Q7KYN5; Q7LDM3; Q7Z2X3; Q8TCG8; Q8WZ42; Q8WZ51; Q8WZ52; Q8WZ53; Q8WZB3; Q92761; Q92762; Q9UD97; Q9UP84; Q9Y6L9"	"Striated muscle contraction pathway; Cardiomyocyte signaling pathways converging on Titin"	"Platelet degranulation ; Striated Muscle Contraction"	"4"	"0"	"145.7"	"182.3"	"89.3"	"119.4"	"92.5"	"107.6"	"192.7"	"212.2"	"294.3"	"405.7"	"458.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5W0B1"	"ORC ubiquitin ligase 1 OS=Homo sapiens OX=9606 GN=OBI1 PE=1 SV=1"	"0.001"	""	"2"	"1"	"2"	"1"	"726"	"81.1"	"5.72"	"251.55"	"2.12"	"1"	"1"	"protein metabolism;other metabolic processes;other biological processes"	"other cell component"	"other molecular function"	"Pf13923"	"79596"	"ENSG00000152193"	"OBI1"	"B2RN99; hsa:79596; Q5W0B1; Q8TBY2; Q9H0T2; Q9H8M0"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IWJ2"	"GRIP and coiled-coil domain-containing protein 2 OS=Homo sapiens OX=9606 GN=GCC2 PE=1 SV=4"	"0.000"	""	"1"	"1"	"2"	"1"	"1684"	"195.8"	"5.14"	"269.65"	"2.12"	"1"	"1"	"cell organization and biogenesis;transport;other biological processes"	"cytosol;ER/Golgi;nucleus"	"other molecular function"	"Pf01465, Pf16704"	"9648"	"ENSG00000135968"	"GCC2"	"A6H8X8; hsa:9648; O15045; Q4ZG46; Q8IWJ2; Q8TDH3; Q9H2G8"	"Deregulation of Rab and Rab effector genes in bladder cancer"	"Signaling by ALK fusions and activated point mutants; Retrograde transport at the Trans-Golgi-Network"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9Y221"	"60S ribosome subunit biogenesis protein NIP7 homolog OS=Homo sapiens OX=9606 GN=NIP7 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"180"	"20.4"	"8.51"	""	"2.12"	""	"1"	"cell organization and biogenesis;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf03657, Pf17833"	"51388"	"ENSG00000132603"	"NIP7"	"B2RD04; hsa:51388; Q9NZZ0; Q9Y221"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UPZ3"	"Hermansky-Pudlak syndrome 5 protein OS=Homo sapiens OX=9606 GN=HPS5 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"1129"	"127.4"	"5.54"	""	"2.12"	""	"1"	"cell organization and biogenesis;stress response;transport;other biological processes"	"cytosol;other cytoplasmic organelle;other cell component"	""	""	"11234"	"ENSG00000110756; ENSG00000288445"	"HPS5"	"A8K6J8; A8K8S1; D3DQX9; D3DQY0; hsa:11234; O95942; Q8N4U0; Q9UPZ3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"P62502"	"Epididymal-specific lipocalin-6 OS=Homo sapiens OX=9606 GN=LCN6 PE=1 SV=1"	""	""	"12"	"1"	"1"	"1"	"163"	"18.0"	"4.92"	""	"2.12"	""	"1"	"other biological processes"	"non-structural extracellular"	"other molecular function"	"Pf00061"	"158062"	"ENSG00000267206"	"LCN6"	"B0QZ80; hsa:158062; P62502; Q71SF6"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q92624"	"Amyloid protein-binding protein 2 OS=Homo sapiens OX=9606 GN=APPBP2 PE=1 SV=2"	""	""	"4"	"1"	"1"	"1"	"585"	"66.8"	"6.90"	""	"2.11"	""	"1"	"protein metabolism;other metabolic processes;transport"	"other membranes;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf13374, Pf13424"	"10513"	"ENSG00000062725"	"APPBP2"	"A8K862; hsa:10513; O95095; Q8WVC9; Q92624"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q16560"	"U11/U12 small nuclear ribonucleoprotein 35 kDa protein OS=Homo sapiens OX=9606 GN=SNRNP35 PE=1 SV=1"	""	""	"6"	"1"	"1"	"1"	"246"	"29.4"	"9.86"	""	"2.11"	""	"1"	"RNA metabolism OR transcription;other metabolic processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"11066"	"ENSG00000184209"	"SNRNP35"	"A8K262; hsa:11066; Q16560; Q5XKN9"	""	"mRNA Splicing - Minor Pathway"	"1"	"0"	"113.8"	"35.6"	"179.5"	"132.1"	"119.3"	"117.6"	"117.1"	"90.7"	"96.1"	"177.0"	"498.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86SQ9"	"Dehydrodolichyl diphosphate synthase complex subunit DHDDS OS=Homo sapiens OX=9606 GN=DHDDS PE=1 SV=3"	"0.000"	""	"3"	"1"	"2"	"1"	"333"	"38.6"	"8.28"	"273.01"	"2.11"	"1"	"1"	"protein metabolism;other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf01255"	"79947"	"ENSG00000117682"	"DHDDS"	"B7Z4B9; B7ZB20; D3DPK7; D3DPK8; D3DPK9; E9KL43; hsa:79947; Q5T0A4; Q86SQ9; Q8NE90; Q9BTG5; Q9BTK3; Q9H905"	""	"Synthesis of Dolichyl-phosphate; Defective DHDDS causes RP59"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5TEU4"	"Arginine-hydroxylase NDUFAF5, mitochondrial OS=Homo sapiens OX=9606 GN=NDUFAF5 PE=1 SV=1"	"0.000"	""	"3"	"1"	"2"	"1"	"345"	"38.9"	"6.57"	"351.80"	"2.10"	"1"	"1"	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf08241"	"79133"	"ENSG00000101247"	"NDUFAF5"	"A8K166; hsa:79133; Q5TEU4; Q6GPH3; Q9H6F4"	""	"Complex I biogenesis"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q8NBQ5"	"Estradiol 17-beta-dehydrogenase 11 OS=Homo sapiens OX=9606 GN=HSD17B11 PE=1 SV=3"	""	""	"5"	"1"	"1"	"1"	"300"	"32.9"	"9.07"	""	"2.10"	""	"1"	""	""	""	""	""	""	""	""	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"O75762"	"Transient receptor potential cation channel subfamily A member 1 OS=Homo sapiens OX=9606 GN=TRPA1 PE=1 SV=3"	""	""	"1"	"1"	"1"	"1"	"1119"	"127.4"	"7.12"	""	"2.09"	""	"1"	"cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"transporter activity;other molecular function"	"Pf00023, Pf00520"	"8989"	"ENSG00000104321"	"TRPA1"	"A6NIN6; hsa:8989; O75762"	"Eicosanoid metabolism via lipooxygenases (LOX)"	"TRP channels"	"2"	"0"	"68.1"	"80.2"	"91.1"	"125.9"	"96.0"	"98.8"	"152.3"	"167.5"	"197.8"	"503.8"	"963.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9UKT8"	"F-box/WD repeat-containing protein 2 OS=Homo sapiens OX=9606 GN=FBXW2 PE=1 SV=2"	""	""	"3"	"1"	"1"	"1"	"454"	"51.5"	"6.58"	""	"2.08"	""	"1"	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00400, Pf00646"	"26190"	"ENSG00000119402"	"FBXW2"	"B3KRL8; hsa:26190; Q4VXH2; Q7Z4V6; Q8WV51; Q9HA09; Q9UKA3; Q9UKT8"	"Wnt signaling pathway and pluripotency"	"Neddylation; Antigen processing: Ubiquitination & Proteasome degradation; Association of TriC/CCT with target proteins during biosynthesis"	"4"	"0"	"219.4"	"185.4"	"229.6"	"263.7"	"228.1"	"249.7"	"292.1"	"293.9"	"330.8"	"515.4"	"685.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q5MIZ7"	"Serine/threonine-protein phosphatase 4 regulatory subunit 3B OS=Homo sapiens OX=9606 GN=PPP4R3B PE=1 SV=2"	""	""	"2"	"1"	"1"	"1"	"849"	"97.4"	"4.96"	""	"2.08"	""	"1"	"protein metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"enzyme regulator activity"	"Pf04802"	"57223"	"ENSG00000275052"	"PPP4R3B"	"hsa:57223; Q5MIZ7; Q6P9B0; Q86XB8; Q9BQJ0; Q9BRK2; Q9H913; Q9P2G0"	"16p11.2 proximal deletion syndrome"	""	"1"	"0"	"59.7"	"46.8"	"73.3"	"76.7"	"66.2"	"62.2"	"84.6"	"79.4"	"95.3"	"167.8"	"270.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q9BZJ6"	"Probable G-protein coupled receptor 63 OS=Homo sapiens OX=9606 GN=GPR63 PE=2 SV=2"	""	""	"2"	"1"	"1"	"1"	"419"	"47.5"	"9.52"	""	"2.08"	""	"1"	"signal transduction"	"plasma membrane;other membranes;cytosol;nucleus;other cell component"	"other molecular function"	"Pf00001"	"81491"	"ENSG00000112218"	"GPR63"	"hsa:81491; Q9BZJ6; Q9UJH3"	"GPCRs, class A rhodopsin-like"	""	"1"	"0"	"57.2"	"31.0"	"82.9"	"74.2"	"59.9"	"61.5"	"75.8"	"70.7"	"91.1"	"128.3"	"226.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q96BN8"	"Ubiquitin thioesterase otulin OS=Homo sapiens OX=9606 GN=OTULIN PE=1 SV=3"	""	""	"4"	"1"	"1"	"1"	"352"	"40.2"	"5.47"	""	"2.07"	""	"1"	"cell-cell signaling;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf16218"	"90268"	"ENSG00000154124"	"OTULIN"	"D3DTD3; hsa:90268; Q8NAS0; Q96BN8; Q96IA3"	""	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Regulation of TNFR1 signaling"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TBF4"	"Zinc finger CCHC-type and RNA-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=ZCRB1 PE=1 SV=2"	"0.001"	""	"5"	"1"	"2"	"1"	"217"	"24.6"	"8.53"	"253.43"	"2.07"	"1"	"1"	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00076, Pf00098"	"85437"	"ENSG00000139168"	"ZCRB1"	"hsa:85437; Q6PJX0; Q8TBF4; Q96TA6"	""	"mRNA Splicing - Minor Pathway; Replication of the SARS-CoV-1 genome; Replication of the SARS-CoV-2 genome"	"3"	"0"	"8.1"	"8.5"	"7.2"	"6.5"	"7.8"	"4.8"	"10.5"	"11.7"	"12.5"	"20.2"	"29.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	""	""	"IsMasterProtein"	"Q7RTP6"	"[F-actin]-monooxygenase MICAL3 OS=Homo sapiens OX=9606 GN=MICAL3 PE=1 SV=2"	""	""	"1"	"1"	"1"	"1"	"2002"	"224.2"	"5.55"	""	"2.07"	""	"1"	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00412, Pf01494, Pf12130"	"57553"	"ENSG00000243156"	"MICAL3"	"B2RXJ5; E9PEF0; hsa:57553; O94909; Q5U4P4; Q6ICK4; Q7RTP6; Q96DF2; Q9P2I3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3F8"	"MICAL-like protein 1 OS=Homo sapiens OX=9606 GN=MICALL1 PE=1 SV=2"	"0.000"	""	"3"	"2"	"2"	"2"	"863"	"93.4"	"7.25"	"892.17"	""	"2"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;developmental processes;other biological processes"	"other membranes;other cytoplasmic organelle"	"other molecular function"	"Pf00307, Pf00412, Pf12130"	"85377"	"ENSG00000100139"	"MICALL1"	"hsa:85377; Q5TI16; Q7RTP5; Q8N3F8; Q8N3N8; Q9BVL9; Q9BY92; Q9UH43; Q9UH44; Q9UH45"	""	""	"0"	"0"	"25.0"	"25.0"	"23.8"	"35.4"	"23.0"	"21.6"	"45.6"	"53.5"	"63.9"	"152.0"	"185.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q93008"	"Probable ubiquitin carboxyl-terminal hydrolase FAF-X OS=Homo sapiens OX=9606 GN=USP9X PE=1 SV=3"	"0.000"	""	"1"	"2"	"2"	"2"	"2570"	"292.1"	"5.80"	"776.79"	""	"2"	""	"protein metabolism;other metabolic processes"	""	"other molecular function"	"Pf00443, Pf12030"	"100971796; 465582"	"ENSPPAG00000039671; ENSPTRG00000045541"	"USP9X"	"A0A2I3RAB4; A0A2J8JDU7; A0A2R9BVD0; A0A6D2WW26"	""	""	"0"	"0"	"148.3"	"148.1"	"167.6"	"177.7"	"116.9"	"145.9"	"167.6"	"178.9"	"210.2"	"412.1"	"617.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P25490"	"Transcriptional repressor protein YY1 OS=Homo sapiens OX=9606 GN=YY1 PE=1 SV=2"	"0.000"	""	"6"	"2"	"2"	"2"	"414"	"44.7"	"6.25"	"771.64"	""	"2"	""	"cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"7528"	"ENSG00000100811"	"YY1"	"hsa:7528; P25490; Q14935"	"Sterol regulatory element-binding proteins (SREBP) signaling; Mammary gland development pathway - Pregnancy and lactation (Stage 3 of 4); Pleural mesothelioma"	"Activation of anterior HOX genes in hindbrain development during early embryogenesis; Estrogen-dependent gene expression; UCH proteinases; DNA Damage Recognition in GG-NER; TFAP2 (AP-2) family regulates transcription of growth factors and their receptors"	"8"	"0"	"491.8"	"334.6"	"454.7"	"484.7"	"419.8"	"413.7"	"499.1"	"478.0"	"524.5"	"499.1"	"665.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4VC05"	"B-cell CLL/lymphoma 7 protein family member A OS=Homo sapiens OX=9606 GN=BCL7A PE=1 SV=1"	"0.000"	""	"5"	"1"	"2"	"1"	"210"	"22.8"	"5.14"	"748.08"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	""	"Pf04714"	"605"	"ENSG00000110987; ENSG00000282873"	"BCL7A"	"B4DJN6; B7ZB21; hsa:605; Q13843; Q14CT7; Q4VC05"	""	""	"0"	"0"	"86.3"	"101.7"	"162.2"	"148.6"	"94.7"	"105.8"	"191.3"	"213.0"	"292.0"	"740.5"	"1024.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P62072"	"Mitochondrial import inner membrane translocase subunit Tim10 OS=Homo sapiens OX=9606 GN=TIMM10 PE=1 SV=1"	"0.000"	""	"16"	"1"	"1"	"1"	"90"	"10.3"	"6.29"	"741.57"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"other membranes;mitochondrion"	"other molecular function"	"Pf02953"	"26519"	"ENSG00000134809"	"TIMM10"	"A8K136; hsa:26519; P62072; Q9WV99; Q9WVA0; Q9Y5J8"	""	"Mitochondrial protein import"	"1"	"0"	"110.8"	"89.9"	"118.8"	"137.8"	"97.4"	"115.2"	"128.1"	"121.5"	"129.1"	"384.1"	"1162.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IZL8"	"Proline-, glutamic acid- and leucine-rich protein 1 OS=Homo sapiens OX=9606 GN=PELP1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1130"	"119.6"	"4.34"	"665.84"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08166, Pf08167"	"27043"	"ENSG00000141456"	"PELP1"	"hsa:27043; O15450; Q5EGN3; Q6NTE6; Q8IZL8; Q96FT1; Q9BU60"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; PTK6 Expression"	"2"	"0"	"47.3"	"46.3"	"54.7"	"71.4"	"40.0"	"19.2"	"76.9"	"83.0"	"103.1"	"220.5"	"318.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"B7ZAP0"	"Rab GTPase-activating protein 1-like, isoform 10 OS=Homo sapiens OX=9606 GN=RABGAP1L PE=1 SV=1"	"0.000"	""	"4"	"1"	"2"	"1"	"253"	"29.0"	"5.33"	"660.86"	""	"1"	""	""	""	""	""	"9910"	"ENSG00000152061"	"RABGAP1L"	"B7ZAA4; B7ZAP0; hsa:9910"	""	""	"0"	"0"	"398.3"	"320.8"	"428.7"	"569.3"	"327.5"	"327.1"	"559.8"	"541.5"	"656.6"	"1206.9"	"1447.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TEW8"	"Partitioning defective 3 homolog B OS=Homo sapiens OX=9606 GN=PARD3B PE=1 SV=2"	"0.000"	""	"2"	"2"	"2"	"2"	"1205"	"132.4"	"8.37"	"654.92"	""	"2"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00595, Pf12053"	"117583"	"ENSG00000116117"	"PARD3B"	"E9PE87; hsa:117583; Q8IUC7; Q8IUC9; Q8TEW8; Q96DK9; Q96N09; Q96NX6; Q96NX7; Q96Q29"	""	""	"0"	"0"	"49.0"	"40.1"	"58.0"	"82.8"	"41.5"	"39.1"	"97.6"	"112.4"	"144.0"	"340.1"	"412.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95926"	"Pre-mRNA-splicing factor SYF2 OS=Homo sapiens OX=9606 GN=SYF2 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"243"	"28.7"	"8.40"	"651.71"	""	"1"	""	"cell cycle OR cell proliferation;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"nucleus;other cell component"	""	"Pf08231"	"25949"	"ENSG00000117614"	"SYF2"	"hsa:25949; O95926; Q5TH73"	""	"mRNA Splicing - Major Pathway"	"1"	"0"	"16.5"	"15.4"	"10.6"	"6.3"	"10.3"	"11.5"	"11.9"	"12.5"	"9.9"	"18.1"	"33.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H6R0"	"ATP-dependent RNA helicase DHX33 OS=Homo sapiens OX=9606 GN=DHX33 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"707"	"78.8"	"8.91"	"644.36"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"translation activity;nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf04408, Pf07717"	"56919"	"ENSG00000005100"	"DHX33"	"B4DHF9; hsa:56919; Q4G149; Q5CZ73; Q9H5M9; Q9H6R0"	""	""	"0"	"0"	"29.4"	"42.7"	"25.9"	"27.5"	"29.8"	"28.6"	"36.1"	"42.8"	"47.3"	"85.8"	"134.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UN37"	"Vacuolar protein sorting-associated protein 4A OS=Homo sapiens OX=9606 GN=VPS4A PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"437"	"48.9"	"7.80"	"641.33"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"27183"	"ENSG00000132612"	"VPS4A"	"B2RCB7; hsa:27183; Q8TF07; Q9UI03; Q9UN37; Q9Y582"	"Ebola virus infection in host; Ciliary landscape"	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT); HCMV Late Events; Sealing of the nuclear envelope (NE) by ESCRT-III"	"6"	"0"	"33.4"	"37.2"	"33.2"	"43.6"	"29.2"	"23.3"	"57.3"	"61.3"	"83.9"	"201.7"	"240.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6I4"	"Ubiquitin carboxyl-terminal hydrolase 3 OS=Homo sapiens OX=9606 GN=USP3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"520"	"58.9"	"8.18"	"637.19"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response"	"nucleus;other cell component"	"other molecular function"	"Pf00443, Pf02148"	"9960"	"ENSG00000140455"	"USP3"	"B4DVU5; F5H1A6; hsa:9960; Q8WVD0; Q9Y6I4"	""	"Ub-specific processing proteases"	"1"	"0"	"85.6"	"91.4"	"98.8"	"96.2"	"86.3"	"78.6"	"140.5"	"143.2"	"150.9"	"159.3"	"144.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43237"	"Cytoplasmic dynein 1 light intermediate chain 2 OS=Homo sapiens OX=9606 GN=DYNC1LI2 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"492"	"54.1"	"6.38"	"633.80"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf05783"	"1783"	"ENSG00000135720"	"DYNC1LI2"	"A8K6V1; B4DZP4; hsa:1783; O43237; Q8TAT3"	"Intraflagellar transport proteins binding to dynein"	"COPI-mediated anterograde transport; Separation of Sister Chromatids; MHC class II antigen presentation; Resolution of Sister Chromatid Cohesion; HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand; RHO GTPases Activate Formins; COPI-independent Golgi-to-ER retrograde traffic; HCMV Early Events; Aggrephagy; EML4 and NUDC in mitotic spindle formation; Amplification  of signal from unattached  kinetochores via a MAD2  inhibitory signal"	"13"	"0"	"20.5"	"16.3"	"29.9"	"24.0"	"22.7"	"17.9"	"35.8"	"32.9"	"34.9"	"96.9"	"142.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9HAF1"	"Chromatin modification-related protein MEAF6 OS=Homo sapiens OX=9606 GN=MEAF6 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"191"	"21.6"	"9.32"	"613.51"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"nucleus;other cell component"	""	"Pf09340"	"64769"	"ENSG00000163875"	"MEAF6"	"B1AK64; hsa:64769; Q4F967; Q7Z311; Q86WE3; Q9HAF1"	""	"HATs acetylate histones; Regulation of TP53 Activity through Acetylation"	"2"	"0"	"96.0"	"60.3"	"63.7"	"73.8"	"51.2"	"70.7"	"80.0"	"81.3"	"59.3"	"53.6"	"58.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P02768"	"Serum albumin OS=Homo sapiens OX=9606 GN=ALB PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"609"	"69.3"	"6.28"	"609.93"	""	"1"	""	"stress response;other biological processes"	"non-structural extracellular;ER/Golgi;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00273"	"213"	"ENSG00000163631"	"ALB"	"E7ESS9; hsa:213; O95574; P02768; P04277; Q13140; Q645G4; Q68DN5; Q6UXK4; Q86YG0; Q8IUK7; Q9P157; Q9P1I7; Q9UHS3; Q9UJZ0"	"Selenium micronutrient network; Vitamin B12 metabolism; Folate metabolism; Complement system; VEGFA-VEGFR2 signaling"	"Scavenging of heme from plasma; Platelet degranulation ; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; Cytoprotection by HMOX1; Aspirin ADME; Ciprofloxacin ADME; Recycling of bile acids and salts; Prednisone ADME; Heme degradation; HDL remodeling; Heme biosynthesis"	"17"	"0"	"30.8"	"18.6"	"112.3"	"40.5"	"11.8"	"14.3"	"43.0"	"44.9"	"54.3"	"75.3"	"123.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TDX7"	"Serine/threonine-protein kinase Nek7 OS=Homo sapiens OX=9606 GN=NEK7 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"302"	"34.5"	"8.25"	"605.97"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf00069"	"140609"	"ENSG00000151414"	"NEK7"	"A6NGT8; hsa:140609; Q8TDX7"	"Ciliary landscape"	"EML4 and NUDC in mitotic spindle formation; Nuclear Pore Complex (NPC) Disassembly; Activation of NIMA Kinases NEK9, NEK6, NEK7"	"4"	"0"	"32.4"	"35.0"	"51.5"	"61.6"	"38.3"	"38.2"	"117.8"	"125.4"	"209.5"	"491.7"	"592.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2X9"	"Zinc finger protein 281 OS=Homo sapiens OX=9606 GN=ZNF281 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"895"	"96.9"	"8.48"	"605.74"	""	"1"	""	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00096"	"23528"	"ENSG00000162702"	"ZNF281"	"A6NF48; B3KMX2; hsa:23528; Q5RKW5; Q9NY92; Q9Y2X9"	"Mesodermal commitment pathway"	""	"1"	"0"	"17.5"	"16.8"	"18.4"	"20.7"	"17.2"	"18.5"	"24.6"	"19.3"	"21.2"	"46.2"	"67.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P63173"	"60S ribosomal protein L38 OS=Homo sapiens OX=9606 GN=RPL38 PE=1 SV=2"	"0.000"	""	"19"	"2"	"2"	"1"	"70"	"8.2"	"10.10"	"597.21"	""	"2"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01781"	"6169"	"ENSG00000172809"	"RPL38"	"B2R5A8; hsa:6169; P23411; P63173"	"Mesodermal commitment pathway; Mesodermal commitment pathway; Cytoplasmic ribosomal proteins"	"L13a-mediated translational silencing of Ceruloplasmin expression; Formation of a pool of free 40S subunits; GTP hydrolysis and joining of the 60S ribosomal subunit; Response of EIF2AK4 (GCN2) to amino acid deficiency; Regulation of expression of SLITs and ROBOs; Major pathway of rRNA processing in the nucleolus and cytosol; Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC); SRP-dependent cotranslational protein targeting to membrane; Viral mRNA Translation; Peptide chain elongation; Selenocysteine synthesis; Eukaryotic Translation Termination; Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)"	"16"	"0"	"106.0"	"53.1"	"70.5"	"94.9"	"80.4"	"101.2"	"98.7"	"91.4"	"145.6"	"191.4"	"196.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P021"	"Cysteine-rich PDZ-binding protein OS=Homo sapiens OX=9606 GN=CRIPT PE=1 SV=1"	"0.000"	""	"12"	"1"	"1"	"1"	"101"	"11.2"	"9.47"	"583.68"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf10235"	"9419"	"ENSG00000119878"	"CRIPT"	"hsa:9419; Q9P021"	""	""	"0"	"0"	"110.9"	"98.5"	"102.3"	"132.8"	"96.4"	"98.6"	"137.1"	"134.1"	"141.7"	"230.9"	"266.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IVW6"	"AT-rich interactive domain-containing protein 3B OS=Homo sapiens OX=9606 GN=ARID3B PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"561"	"60.6"	"7.52"	"579.65"	""	"1"	""	"other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf01388"	"10620"	"ENSG00000179361"	"ARID3B"	"hsa:10620; O95443; Q59HC9; Q6P9C9; Q8IVW6"	""	""	"0"	"0"	"30.5"	"24.5"	"27.6"	"29.9"	"22.6"	"29.9"	"31.5"	"40.5"	"34.7"	"58.4"	"67.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08379"	"Golgin subfamily A member 2 OS=Homo sapiens OX=9606 GN=GOLGA2 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1002"	"113.0"	"5.02"	"563.38"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf15070, Pf19046"	"2801"	"ENSG00000167110"	"GOLGA2"	"A0A0C4DGS5; hsa:2801; Q08379; Q6GRM9; Q9BRB0; Q9NYF9"	""	"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models; COPI-mediated anterograde transport; COPII-mediated vesicle transport; Golgi Cisternae Pericentriolar Stack Reorganization"	"4"	"0"	"22.9"	"20.1"	"24.0"	"29.8"	"21.0"	"17.4"	"48.9"	"56.9"	"84.9"	"203.7"	"238.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6UWZ7"	"BRCA1-A complex subunit Abraxas 1 OS=Homo sapiens OX=9606 GN=ABRAXAS1 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"409"	"46.6"	"7.05"	"558.85"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"cytoskeletal activity;other molecular function"	""	"84142"	"ENSG00000163322"	"ABRAXAS1"	"A5JJ07; hsa:84142; Q6UWZ7; Q9H8I1; Q9H9N4"	"5q35 copy number variation"	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; G2/M DNA damage checkpoint; Metalloprotease DUBs; Processing of DNA double-strand break ends; Nonhomologous End-Joining (NHEJ)"	"6"	"0"	"70.2"	"71.5"	"78.0"	"109.0"	"72.3"	"64.4"	"126.6"	"151.2"	"188.3"	"380.0"	"448.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P15336"	"Cyclic AMP-dependent transcription factor ATF-2 OS=Homo sapiens OX=9606 GN=ATF2 PE=1 SV=4"	"0.000"	""	"3"	"1"	"1"	"1"	"505"	"54.5"	"7.88"	"556.46"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"other membranes;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00170"	"1386"	"ENSG00000115966"	"ATF2"	"A1L3Z2; A4D7U4; A4D7U5; A4D7V1; D3DPE9; G8JLM5; hsa:1386; P15336; Q13000; Q3B7B7; Q4ZFU9; Q53RY2; Q8TAR1; Q96JT8"	"Energy metabolism; IL-1 signaling pathway; B cell receptor signaling pathway; AGE/RAGE pathway; ATM signaling pathway; Interleukin-1 (IL-1) structural pathway; Myometrial relaxation and contraction pathways; MAPK signaling pathway; ATM signaling in development and disease ; VEGFA-VEGFR2 signaling; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; DNA IR-double strand breaks and cellular response via ATM; Ethanol effects on histone modifications; p38 MAPK signaling pathway; PI3K-Akt signaling pathway; Thermogenesis; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Host-pathogen interaction of human coronaviruses - MAPK signaling; Pleural mesothelioma; 10q11.21q11.23 copy number variation syndrome; T-cell receptor signaling pathway"	"NGF-stimulated transcription; Heme signaling; Regulation of PTEN gene transcription; TP53 Regulates Transcription of DNA Repair Genes; Circadian Clock; Transcriptional activation of mitochondrial biogenesis; Estrogen-dependent gene expression; HATs acetylate histones; Activation of the AP-1 family of transcription factors; Response of EIF2AK4 (GCN2) to amino acid deficiency"	"34"	"0"	"23.6"	"22.2"	"30.6"	"33.1"	"21.0"	"19.9"	"25.0"	"31.1"	"36.3"	"76.9"	"94.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKK9"	"ADP-sugar pyrophosphatase OS=Homo sapiens OX=9606 GN=NUDT5 PE=1 SV=1"	"0.000"	""	"7"	"1"	"1"	"1"	"219"	"24.3"	"4.94"	"552.22"	""	"1"	""	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"11164"	"ENSG00000165609"	"NUDT5"	"A8K516; hsa:11164; Q6IAG0; Q9UH49; Q9UKK9"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	"14.5"	"9.4"	"19.9"	"22.1"	"8.8"	"6.2"	"16.4"	"15.5"	"17.0"	"27.7"	"40.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P287"	"BRCA2 and CDKN1A-interacting protein OS=Homo sapiens OX=9606 GN=BCCIP PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"314"	"36.0"	"4.61"	"547.50"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus"	"enzyme regulator activity;cytoskeletal activity"	"Pf13862"	"56647"	"ENSG00000107949"	"BCCIP"	"B3KP45; hsa:56647; Q8ND15; Q96GC4; Q9P287; Q9P288"	""	""	"0"	"0"	"9.0"	"9.2"	"14.9"	"20.1"	"6.5"	"4.5"	"18.9"	"14.6"	"18.8"	"15.9"	"33.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6BDS2"	"UHRF1-binding protein 1 OS=Homo sapiens OX=9606 GN=UHRF1BP1 PE=1 SV=1"	"0.000"	""	"1"	"2"	"2"	"2"	"1440"	"159.4"	"6.14"	"541.56"	""	"2"	""	""	"other cytoplasmic organelle"	"other molecular function"	"Pf12624"	"54887"	"ENSG00000065060"	"BLTP3A"	"hsa:54887; Q6BDS2; Q9NXE0"	""	""	"0"	"0"	"94.3"	"79.2"	"73.3"	"81.7"	"83.9"	"78.1"	"105.0"	"123.6"	"147.0"	"244.0"	"251.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92615"	"La-related protein 4B OS=Homo sapiens OX=9606 GN=LARP4B PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"738"	"80.5"	"6.92"	"540.86"	""	"1"	""	"other biological processes"	"cytosol;translational apparatus;nucleus;other cell component"	"nucleic acid binding activity"	"Pf05383"	"23185"	"ENSG00000107929"	"LARP4B"	"A7MD20; hsa:23185; Q5T3R3; Q5T3R4; Q5T3R5; Q68CY4; Q92615"	""	""	"0"	"0"	"36.7"	"38.7"	"49.1"	"56.2"	"34.9"	"38.1"	"56.9"	"57.8"	"55.8"	"85.6"	"88.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P27824"	"Calnexin OS=Homo sapiens OX=9606 GN=CANX PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"592"	"67.5"	"4.60"	"529.56"	""	"1"	""	"protein metabolism;other metabolic processes;stress response;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;translational apparatus;nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00262"	"821"	"ENSG00000127022; ENSG00000283777"	"CANX"	"B2R5V8; B4DGP8; B4E2T8; D3DWQ3; D6R9K3; hsa:821; P27824"	"15q11q13 copy number variation"	"Maturation of spike protein; MHC class II antigen presentation; Antigen Presentation: Folding, assembly and peptide loading of class I MHC; Interleukin-35 Signalling; Interleukin-27 signaling; Assembly of Viral Components at the Budding Site; Calnexin/calreticulin cycle; Maturation of spike protein"	"9"	"0"	"36.0"	"35.8"	"53.3"	"106.7"	"30.0"	"26.1"	"56.8"	"61.6"	"92.1"	"263.0"	"322.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y365"	"START domain-containing protein 10 OS=Homo sapiens OX=9606 GN=STARD10 PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"291"	"33.0"	"7.12"	"528.89"	""	"1"	""	"transport"	"other membranes;cytosol;cytoskeleton;other cell component"	"other molecular function"	"Pf01852"	"10809"	"ENSG00000214530"	"STARD10"	"hsa:10809; O60532; Q9Y365"	""	"Synthesis of PC"	"1"	"0"	"0.0"	"0.0"	"2.3"	"0.0"	"1.7"	"3.0"	"11.9"	"8.9"	"19.7"	"165.8"	"148.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P43155"	"Carnitine O-acetyltransferase OS=Homo sapiens OX=9606 GN=CRAT PE=1 SV=5"	"0.000"	""	"2"	"1"	"1"	"1"	"626"	"70.8"	"8.44"	"524.22"	""	"1"	""	"other metabolic processes"	"other membranes;cytosol;mitochondrion;ER/Golgi;other cytoplasmic organelle"	"other molecular function"	"Pf00755"	"1384"	"ENSG00000095321"	"CRAT"	"P43155; Q5T952; Q9BW16"	"Fatty acid beta-oxidation"	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"3"	"0"	"47.0"	"46.7"	"53.9"	"50.6"	"47.5"	"46.7"	"91.3"	"76.7"	"123.1"	"402.4"	"645.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6X9"	"ATPase MORC2 OS=Homo sapiens OX=9606 GN=MORC2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1032"	"117.8"	"8.38"	"522.62"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf07496, Pf13589, Pf17942"	"22880"	"ENSG00000133422"	"MORC2"	"B2RNB1; hsa:22880; Q9UF28; Q9Y6V2; Q9Y6X9"	""	"Fatty acyl-CoA biosynthesis"	"1"	"0"	"27.2"	"33.5"	"29.2"	"34.0"	"30.4"	"23.2"	"42.7"	"50.4"	"58.7"	"163.1"	"209.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15631"	"Translin OS=Homo sapiens OX=9606 GN=TSN PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"228"	"26.2"	"6.44"	"519.83"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01997"	"7247"	"ENSG00000211460"	"TSN"	"B7Z3X8; hsa:7247; Q15631; Q5U0K7"	""	"Small interfering RNA (siRNA) biogenesis"	"1"	"0"	"9.1"	"15.4"	"11.3"	"26.3"	"8.4"	"11.6"	"22.3"	"18.4"	"29.9"	"61.3"	"90.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2X3"	"Nucleolar protein 58 OS=Homo sapiens OX=9606 GN=NOP58 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"529"	"59.5"	"8.92"	"501.44"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01798, Pf08156"	"51602"	"ENSG00000055044"	"NOP58"	"hsa:51602; Q53SA4; Q6PK08; Q9P036; Q9UFN3; Q9Y2X3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol; SUMOylation of RNA binding proteins; rRNA modification in the nucleus and cytosol"	"3"	"0"	"104.5"	"99.7"	"117.3"	"146.1"	"93.8"	"111.4"	"176.2"	"195.5"	"259.8"	"596.1"	"818.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75351"	"Vacuolar protein sorting-associated protein 4B OS=Homo sapiens OX=9606 GN=VPS4B PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"444"	"49.3"	"7.23"	"498.92"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;nucleus;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00004, Pf04212, Pf09336, Pf17862"	"9525"	"ENSG00000119541"	"VPS4B"	"hsa:9525; O75351; Q69HW4; Q9GZS7"	""	"Budding and maturation of HIV virion; Endosomal Sorting Complex Required For Transport (ESCRT)"	"2"	"0"	"14.9"	"17.4"	"10.6"	"13.9"	"6.5"	"10.1"	"13.3"	"14.2"	"22.6"	"61.2"	"135.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99698"	"Lysosomal-trafficking regulator OS=Homo sapiens OX=9606 GN=LYST PE=1 SV=3"	"0.000"	""	"0"	"2"	"2"	"2"	"3801"	"428.9"	"6.61"	"498.64"	""	"2"	""	"cell organization and biogenesis;stress response;transport;other biological processes"	"other membranes;cytosol;cytoskeleton"	"other molecular function"	"Pf00400, Pf02138, Pf14844"	"1130"	"ENSG00000143669"	"LYST"	"hsa:1130; O43274; Q5T2U9; Q96TD7; Q96TD8; Q99698; Q99709; Q9H133"	""	""	"0"	"0"	"262.8"	"240.2"	"288.6"	"305.3"	"226.4"	"238.3"	"344.9"	"355.1"	"415.2"	"959.6"	"1383.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96HE7"	"ERO1-like protein alpha OS=Homo sapiens OX=9606 GN=ERO1A PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"468"	"54.4"	"5.68"	"498.30"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;transport;signal transduction;other biological processes"	"non-structural extracellular;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf04137"	"30001"	"ENSG00000197930"	"ERO1A"	"A8K9X4; A8MYW1; hsa:30001; Q7LD45; Q96HE7; Q9P1Q9; Q9UKV6"	""	"Detoxification of Reactive Oxygen Species"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P78364"	"Polyhomeotic-like protein 1 OS=Homo sapiens OX=9606 GN=PHC1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"1004"	"105.5"	"9.03"	"492.36"	""	"1"	""	"cell organization and biogenesis"	"nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00536, Pf16616"	"1911"	"ENSG00000111752"	"PHC1"	"D3DUV4; hsa:1911; P78364; Q8WVM3; Q9BU63"	"Pleural mesothelioma"	"Oxidative Stress Induced Senescence; SUMOylation of DNA damage response and repair proteins; SUMOylation of chromatin organization proteins; SUMOylation of RNA binding proteins; SUMOylation of transcription cofactors; SUMOylation of DNA methylation proteins; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known; Regulation of PTEN gene transcription; Transcriptional Regulation by E2F6"	"10"	"0"	"22.5"	"18.1"	"20.7"	"21.8"	"20.6"	"19.9"	"26.0"	"26.5"	"33.1"	"55.2"	"67.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PIJ6"	"F-box only protein 38 OS=Homo sapiens OX=9606 GN=FBXO38 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1188"	"133.9"	"6.33"	"491.64"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf00646"	"81545"	"ENSG00000145868"	"FBXO38"	"hsa:81545; Q6PIJ6; Q6PK72; Q7Z2U0; Q86VN3; Q9BXY6; Q9H837; Q9HC40"	""	""	"0"	"0"	"0.0"	"3.6"	"2.9"	"5.0"	"3.3"	"0.0"	"3.4"	"6.6"	"5.3"	"35.3"	"59.6"	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UH92"	"Max-like protein X OS=Homo sapiens OX=9606 GN=MLX PE=1 SV=2"	"0.000"	""	"2"	"1"	"2"	"1"	"298"	"33.3"	"8.06"	"487.33"	""	"1"	""	"other biological processes"	"other membranes;cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00010"	"6945"	"ENSG00000108788"	"MLX"	"A8K2J3; B2RAV8; B2RD73; hsa:6945; Q53XM6; Q96FL2; Q9H2V0; Q9H2V1; Q9H2V2; Q9NXN3; Q9UH92"	"Nonalcoholic fatty liver disease"	"ChREBP activates metabolic gene expression"	"2"	"0"	"94.7"	"131.0"	"35.1"	"240.1"	"95.3"	"86.4"	"190.0"	"1013.5"	"248.6"	"1603.5"	"237.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N3X1"	"Formin-binding protein 4 OS=Homo sapiens OX=9606 GN=FNBP4 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1017"	"110.2"	"4.74"	"485.75"	""	"1"	""	""	"nucleus"	""	"Pf00397"	"23360"	"ENSG00000109920; ENSG00000285182"	"FNBP4"	"hsa:23360; Q8N3X1; Q9H985; Q9NT81; Q9Y2L7"	""	""	"0"	"0"	"42.2"	"26.6"	"41.0"	"33.7"	"27.8"	"37.9"	"29.2"	"31.9"	"32.3"	"32.0"	"45.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6DKI1"	"60S ribosomal protein L7-like 1 OS=Homo sapiens OX=9606 GN=RPL7L1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"255"	"29.7"	"10.52"	"482.99"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes"	"cytosol;translational apparatus;nucleus"	"other molecular function"	"Pf00327, Pf08079"	"285855"	"ENSG00000146223"	"RPL7L1"	"A8K7D4; B7Z652; hsa:285855; Q5TFZ5; Q6DKI1; Q6PEK3"	""	""	"0"	"0"	"112.6"	"107.9"	"122.3"	"136.7"	"108.0"	"111.8"	"156.1"	"166.5"	"189.2"	"324.0"	"494.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P45974"	"Ubiquitin carboxyl-terminal hydrolase 5 OS=Homo sapiens OX=9606 GN=USP5 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"858"	"95.7"	"5.03"	"482.51"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"cytosol;nucleus;other cytoplasmic organelle"	"other molecular function"	"Pf00443, Pf00627, Pf02148, Pf17807"	"8078"	"ENSG00000111667"	"USP5"	"D3DUS7; D3DUS8; hsa:8078; P45974; Q96J22"	"IL-18 signaling pathway"	"Synthesis of active ubiquitin: roles of E1 and E2 enzymes; Ub-specific processing proteases"	"3"	"0"	"38.4"	"33.1"	"41.0"	"85.0"	"31.9"	"32.2"	"56.7"	"57.8"	"65.0"	"128.4"	"132.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BV44"	"THUMP domain-containing protein 3 OS=Homo sapiens OX=9606 GN=THUMPD3 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"507"	"57.0"	"6.37"	"475.28"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf01170, Pf02926"	"25917"	"ENSG00000134077"	"THUMPD3"	"hsa:25917; Q9BV44; Q9H8V6; Q9NVC1; Q9UFS3"	""	""	"0"	"0"	"11.3"	"6.9"	"16.0"	"25.5"	"10.1"	"11.6"	"18.6"	"25.2"	"38.9"	"162.5"	"237.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P32780"	"General transcription factor IIH subunit 1 OS=Homo sapiens OX=9606 GN=GTF2H1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"548"	"62.0"	"8.66"	"473.67"	""	"1"	""	"DNA metabolism;RNA metabolism OR transcription;other metabolic processes;stress response;signal transduction;other biological processes"	"nucleus"	"other molecular function"	"Pf03909, Pf08567"	"2965"	"ENSG00000110768; ENSG00000288114"	"GTF2H1"	"B3KXE0; D3DQY2; hsa:2965; P32780; Q6I9Y7; Q9H5K5; Q9NQD9"	"Eukaryotic transcription initiation; Nucleotide excision repair; DNA repair pathways, full network; Nucleotide excision repair in xeroderma pigmentosum"	"NoRC negatively regulates rRNA expression; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Formation of Incision Complex in GG-NER; Dual Incision in GG-NER"	"33"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00255"	"Menin OS=Homo sapiens OX=9606 GN=MEN1 PE=1 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"615"	"68.0"	"6.55"	"454.56"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05053"	"4221"	"ENSG00000133895"	"MEN1"	"A5HBC6; A5HBC7; A5HBC8; A5HBC9; A5HBD0; A5HBD1; A5HBD2; hsa:4221; O00255; O00632; Q9BUF0; Q9BUK2"	"10q11.21q11.23 copy number variation syndrome"	"RHO GTPases activate IQGAPs; Formation of WDR5-containing histone-modifying complexes; Formation of the beta-catenin:TCF transactivating complex; SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Deactivation of the beta-catenin transactivating complex; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation"	"8"	"0"	"6.0"	"8.5"	"8.9"	"11.7"	"8.2"	"9.0"	"11.4"	"16.3"	"27.9"	"72.8"	"86.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JJ7"	"Protein disulfide-isomerase TMX3 OS=Homo sapiens OX=9606 GN=TMX3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"454"	"51.8"	"4.91"	"445.86"	""	"1"	""	"protein metabolism;other metabolic processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00085, Pf13848"	"54495"	"ENSG00000166479"	"TMX3"	"B3KV75; hsa:54495; Q52LT7; Q8N5J0; Q96JJ7; Q9NWJ9"	""	"Platelet degranulation"	"1"	"0"	"27.1"	"21.8"	"27.1"	"31.7"	"25.1"	"25.3"	"42.4"	"40.2"	"50.4"	"142.1"	"191.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99614"	"Tetratricopeptide repeat protein 1 OS=Homo sapiens OX=9606 GN=TTC1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"292"	"33.5"	"4.84"	"445.74"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol"	"other molecular function"	"Pf00515, Pf13181"	"7265"	"ENSG00000113312"	"TTC1"	"B2RCT2; D3DQJ8; hsa:7265; Q99614; Q9BVT3"	""	""	"0"	"0"	"12.2"	"22.2"	"7.7"	"19.4"	"7.7"	"11.7"	"21.8"	"21.1"	"21.2"	"36.7"	"36.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BY32"	"Inosine triphosphate pyrophosphatase OS=Homo sapiens OX=9606 GN=ITPA PE=1 SV=2"	"0.000"	""	"6"	"1"	"1"	"1"	"194"	"21.4"	"5.66"	"445.66"	""	"1"	""	"cell organization and biogenesis;other metabolic processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf01725"	"3704"	"ENSG00000125877"	"ITPA"	"A2A2N2; A4UIM5; B2BCH7; hsa:3704; O14878; Q5JWH4; Q9BY32; Q9BYN1; Q9BYX0; Q9H3H8"	""	"Purine catabolism; Ribavirin ADME"	"2"	"0"	"41.7"	"42.4"	"64.3"	"63.0"	"40.3"	"34.3"	"92.4"	"83.8"	"103.3"	"209.7"	"248.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96GM5"	"SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1 OS=Homo sapiens OX=9606 GN=SMARCD1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"515"	"58.2"	"9.25"	"444.54"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf02201"	"6602"	"ENSG00000066117"	"SMARCD1"	"A6NN27; hsa:6602; Q92924; Q96GM5; Q9Y635"	"Androgen receptor network in prostate cancer; Tumor suppressor activity of SMARCB1; Thermogenesis; Kleefstra syndrome"	"RMTs methylate histone arginines; RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known"	"6"	"0"	"19.9"	"14.5"	"20.7"	"16.7"	"14.5"	"16.6"	"23.1"	"31.5"	"26.7"	"58.5"	"60.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94927"	"HAUS augmin-like complex subunit 5 OS=Homo sapiens OX=9606 GN=HAUS5 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"633"	"71.6"	"8.51"	"442.29"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton"	""	"Pf14817"	"23354"	"ENSG00000249115"	"HAUS5"	"B2RXK1; hsa:23354; O94927; Q6P2P7; Q7L3D5; Q96CT8"	""	"Recruitment of NuMA to mitotic centrosomes; Regulation of PLK1 Activity at G2/M Transition; Loss of Nlp from mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes; Anchoring of the basal body to the plasma membrane; AURKA Activation by TPX2"	"7"	"0"	"65.5"	"60.8"	"58.4"	"64.2"	"54.3"	"55.5"	"81.5"	"101.0"	"134.0"	"260.3"	"384.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q99418"	"Cytohesin-2 OS=Homo sapiens OX=9606 GN=CYTH2 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"400"	"46.5"	"5.54"	"439.47"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;ER/Golgi;other cell component"	"enzyme regulator activity;other molecular function"	"Pf00169, Pf01369"	"9266"	"ENSG00000105443"	"CYTH2"	"A8K8P0; hsa:9266; Q8IXY9; Q92958; Q99418"	"2q37 copy number variation syndrome"	"Intra-Golgi traffic"	"2"	"0"	"9.7"	"7.5"	"10.1"	"10.4"	"9.0"	"13.0"	"35.8"	"36.6"	"48.9"	"92.3"	"106.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92551"	"Inositol hexakisphosphate kinase 1 OS=Homo sapiens OX=9606 GN=IP6K1 PE=1 SV=3"	"0.000"	""	"3"	"1"	"1"	"1"	"441"	"50.2"	"7.24"	"438.41"	""	"1"	""	"other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"kinase activity;other molecular function"	"Pf03770"	"9807"	"ENSG00000176095"	"IP6K1"	"A8K157; A8MUX4; hsa:9807; Q7L3I7; Q92551; Q96E38"	""	"Synthesis of pyrophosphates in the cytosol; Synthesis of IPs in the nucleus"	"2"	"0"	"5.9"	"4.6"	"2.7"	"5.6"	"4.2"	"4.1"	"22.2"	"37.9"	"48.6"	"76.3"	"76.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P34741"	"Syndecan-2 OS=Homo sapiens OX=9606 GN=SDC2 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"201"	"22.1"	"4.86"	"438.30"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf01034"	"6383"	"ENSG00000169439"	"SDC2"	"B3KQA3; hsa:6383; P34741; Q6PIS6; Q9H6V1"	"miRNA targets in ECM and membrane receptors"	"EPHB-mediated forward signaling; Cell surface interactions at the vascular wall; Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs); Post-translational protein phosphorylation; A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport; Syndecan interactions"	"16"	"0"	"21.0"	"29.9"	"22.6"	"23.3"	"14.8"	"21.7"	"36.7"	"40.8"	"51.2"	"81.3"	"108.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14908"	"PDZ domain-containing protein GIPC1 OS=Homo sapiens OX=9606 GN=GIPC1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"333"	"36.0"	"6.28"	"437.47"	""	"1"	""	"cell-cell signaling;transport;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00595"	"10755"	"ENSG00000123159"	"GIPC1"	"A8K4I3; A8MZG3; hsa:10755; O14908; Q9BTC9"	"VEGFA-VEGFR2 signaling"	""	"1"	"0"	"14.4"	"18.2"	"10.3"	"22.7"	"18.2"	"16.2"	"44.3"	"44.6"	"64.5"	"163.8"	"264.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95619"	"YEATS domain-containing protein 4 OS=Homo sapiens OX=9606 GN=YEATS4 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"227"	"26.5"	"8.41"	"433.50"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"other membranes;nucleus;other cell component"	"cytoskeletal activity;other molecular function"	"Pf03366"	"8089"	"ENSG00000127337"	"YEATS4"	"hsa:8089; O95619; Q9NQD0"	""	"HATs acetylate histones; Activation of the TFAP2 (AP-2) family of transcription factors"	"2"	"0"	"136.3"	"83.4"	"146.6"	"181.7"	"113.4"	"132.3"	"196.6"	"247.9"	"220.6"	"693.9"	"905.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55199"	"RNA polymerase II elongation factor ELL OS=Homo sapiens OX=9606 GN=ELL PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"621"	"68.2"	"9.33"	"426.91"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf07303, Pf10390"	"8178"	"ENSG00000105656"	"ELL"	"hsa:8178; P55199"	"Interactome of polycomb repressive complex 2 (PRC2)"	"Formation of RNA Pol II elongation complex ; Formation of HIV elongation complex in the absence of HIV Tat; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; Transcription-Coupled Nucleotide Excision Repair (TC-NER)"	"14"	"0"	"18.3"	"18.1"	"10.2"	"13.8"	"12.9"	"17.1"	"16.9"	"16.0"	"15.4"	"28.2"	"44.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NPL8"	"Complex I assembly factor TIMMDC1, mitochondrial OS=Homo sapiens OX=9606 GN=TIMMDC1 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"285"	"32.2"	"8.50"	"426.02"	""	"1"	""	""	"other membranes;mitochondrion;nucleus"	""	"Pf02466"	"51300"	"ENSG00000113845"	"TIMMDC1"	"D3DN81; hsa:51300; Q6IAJ7; Q6UWU6; Q9NPL8; Q9NPR3; Q9NPS5; Q9P0Y6"	""	"Complex I biogenesis"	"1"	"0"	"113.2"	"89.9"	"89.8"	"102.1"	"85.8"	"87.9"	"116.1"	"130.4"	"182.2"	"347.7"	"481.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P12931"	"Proto-oncogene tyrosine-protein kinase Src OS=Homo sapiens OX=9606 GN=SRC PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"536"	"59.8"	"7.42"	"422.23"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;nucleus;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;kinase activity;other molecular function"	"Pf00017, Pf00018, Pf07714"	"6714"	"ENSG00000197122"	"SRC"	"E1P5V4; hsa:6714; P12931; Q76P87; Q86VB9; Q9H5A8"	"Androgen receptor signaling pathway; Angiogenesis; Integrin-mediated cell adhesion; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; Prolactin signaling pathway; Microtubule cytoskeleton regulation; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; AGE/RAGE pathway; Interleukin-11 signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Alpha 6 beta 4 signaling pathway; Aryl hydrocarbon receptor pathway; Bladder cancer; IL-3 signaling pathway; Aryl hydrocarbon receptor pathway; Pregnane X receptor pathway; Nuclear receptors meta-pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; Amplification and expansion of oncogenic pathways as metastatic traits; Physico-chemical features and toxicity-associated pathways; VEGFA-VEGFR2 signaling; Robo4 and VEGF signaling pathways crosstalk; Fibrin complement receptor 3 signaling pathway; Acute viral myocarditis; NRF2-ARE regulation; EGF/EGFR signaling pathway; Relationship between inflammation, COX-2 and EGFR; Mechanoregulation and pathology of YAP/TAZ via Hippo and non-Hippo mechanisms; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Thyroid hormones production and peripheral downstream signaling effects; Netrin-UNC5B signaling pathway; EGFR tyrosine kinase inhibitor resistance; Pleural mesothelioma; CCL18 signaling pathway; GDNF signaling; TROP2 regulatory signaling; A network map of Macrophage-stimulating protein (MSP) signaling; 5q35 copy number variation; EPO receptor signaling; Notch signaling pathway; ErbB signaling pathway"	"G alpha (i) signalling events; Extra-nuclear estrogen signaling; GPER1 signaling; PIP3 activates AKT signaling; Signaling by BRAF and RAF1 fusions; Regulation of RUNX3 expression and activity; RHOU GTPase cycle; Constitutive Signaling by Aberrant PI3K in Cancer; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; DCC mediated attractive signaling; Downstream signal transduction; Signaling by ERBB2; Nuclear signaling by ERBB4; RAF activation; GAB1 signalosome; MET activates PTK2 signaling; Signaling by CSF1 (M-CSF) in myeloid cells; RUNX2 regulates osteoblast differentiation; Long-term potentiation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; InlA-mediated entry of Listeria monocytogenes into host cells; Regulation of commissural axon pathfinding by SLIT and ROBO; Netrin mediated repulsion signals; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; GRB2:SOS provides linkage to MAPK signaling for Integrins ; p130Cas linkage to MAPK signaling for integrins; Activated NTRK2 signals through FYN; Downregulation of ERBB4 signaling; Regulation of RUNX1 Expression and Activity; Activated NTRK3 signals through PI3K"	"87"	"0"	"8.9"	"7.2"	"9.7"	"18.0"	"4.7"	"5.8"	"16.3"	"23.2"	"41.3"	"156.4"	"278.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86U44"	"N6-adenosine-methyltransferase catalytic subunit OS=Homo sapiens OX=9606 GN=METTL3 PE=1 SV=2"	"0.000"	""	"3"	"1"	"1"	"1"	"580"	"64.4"	"6.42"	"407.18"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf05063"	"56339"	"ENSG00000165819"	"METTL3"	"hsa:56339; O14736; Q86U44; Q86V05; Q9HB32"	"mRNA processing"	"Processing of Capped Intron-Containing Pre-mRNA"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O15460"	"Prolyl 4-hydroxylase subunit alpha-2 OS=Homo sapiens OX=9606 GN=P4HA2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"535"	"60.9"	"5.71"	"402.84"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;ER/Golgi;nucleus;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"8974"	"ENSG00000072682"	"P4HA2"	"D3DQ85; D3DQ86; hsa:8974; O15460; Q8WWN0"	"VEGFA-VEGFR2 signaling; Amino acid metabolism; Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"4"	"0"	"3.9"	"2.2"	"4.8"	"12.1"	"8.0"	"4.1"	"11.1"	"9.5"	"18.4"	"29.2"	"30.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86SQ0"	"Pleckstrin homology-like domain family B member 2 OS=Homo sapiens OX=9606 GN=PHLDB2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1253"	"142.1"	"7.43"	"394.02"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;other cell component"	""	"Pf00169"	"90102"	"ENSG00000144824"	"PHLDB2"	"A5PKZ3; hsa:90102; Q59EA8; Q68CY3; Q6NT98; Q86SQ0; Q8N8U8; Q8NAB1; Q8NCU5"	"Microtubule cytoskeleton regulation"	""	"1"	"0"	"59.8"	"61.6"	"55.1"	"98.2"	"52.6"	"38.4"	"88.3"	"120.0"	"138.1"	"206.1"	"221.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6PI78"	"Transmembrane protein 65 OS=Homo sapiens OX=9606 GN=TMEM65 PE=1 SV=2"	"0.000"	""	"6"	"1"	"1"	"1"	"240"	"25.5"	"8.60"	"393.91"	""	"1"	""	"developmental processes;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	""	"Pf10507"	"157378"	"ENSG00000164983"	"TMEM65"	"hsa:157378; Q6PI78; Q8N5G8; Q8WVK5"	""	""	"0"	"0"	"3.5"	"0.0"	"6.4"	"10.1"	"1.7"	"3.8"	"9.2"	"8.3"	"8.2"	"45.0"	"82.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O14646"	"Chromodomain-helicase-DNA-binding protein 1 OS=Homo sapiens OX=9606 GN=CHD1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1710"	"196.6"	"7.14"	"393.09"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00176, Pf00271, Pf00385, Pf13907, Pf18375"	"1105"	"ENSG00000153922"	"CHD1"	"hsa:1105; O14646; Q17RZ3"	""	"Estrogen-dependent gene expression"	"1"	"0"	"4.6"	"12.2"	"10.8"	"8.5"	"7.2"	"4.4"	"11.9"	"14.8"	"19.6"	"57.0"	"91.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UKG9"	"Peroxisomal carnitine O-octanoyltransferase OS=Homo sapiens OX=9606 GN=CROT PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"612"	"70.1"	"7.08"	"390.83"	""	"1"	""	"other metabolic processes;transport"	"cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf00755"	"54677"	"ENSG00000005469"	"CROT"	"A4D1D6; E7EQF2; hsa:54677; Q86V17; Q8IUW9; Q9UKG9; Q9Y6I2"	""	"Peroxisomal protein import; Beta-oxidation of pristanoyl-CoA"	"2"	"0"	"29.2"	"25.0"	"31.6"	"37.2"	"25.1"	"30.6"	"95.8"	"106.5"	"203.6"	"439.3"	"601.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT92"	"Trichoplein keratin filament-binding protein OS=Homo sapiens OX=9606 GN=TCHP PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"498"	"61.0"	"6.54"	"386.81"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	""	"Pf13868"	"84260"	"ENSG00000139437"	"TCHP"	"hsa:84260; Q8NAG0; Q9BT92"	""	""	"0"	"0"	"13.4"	"9.6"	"8.9"	"16.5"	"9.6"	"9.1"	"11.1"	"12.5"	"13.3"	"20.4"	"29.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14192"	"Four and a half LIM domains protein 2 OS=Homo sapiens OX=9606 GN=FHL2 PE=1 SV=3"	"0.000"	""	"4"	"1"	"1"	"1"	"279"	"32.2"	"7.55"	"382.34"	""	"1"	""	"developmental processes;other biological processes"	"cytoskeleton;nucleus"	"other molecular function"	"Pf00412"	"2274"	"ENSG00000115641"	"FHL2"	"hsa:2274; Q13229; Q13644; Q14192; Q2I5I4; Q5TM15; Q9P294"	"Androgen receptor signaling pathway; RANKL/RANK signaling pathway; Ectoderm differentiation; VEGFA-VEGFR2 signaling"	"PPARA activates gene expression"	"5"	"0"	"105.2"	"127.6"	"90.4"	"122.3"	"100.3"	"77.8"	"160.1"	"178.5"	"195.4"	"354.0"	"363.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2R4"	"Probable ATP-dependent RNA helicase DDX52 OS=Homo sapiens OX=9606 GN=DDX52 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"599"	"67.5"	"9.67"	"378.20"	""	"1"	""	""	""	""	""	""	""	""	""	""	""	"0"	"0"	"11.3"	"15.0"	"19.5"	"26.7"	"12.9"	"16.1"	"27.4"	"33.3"	"46.6"	"143.7"	"187.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P56211"	"cAMP-regulated phosphoprotein 19 OS=Homo sapiens OX=9606 GN=ARPP19 PE=1 SV=2"	"0.000"	""	"7"	"1"	"1"	"1"	"112"	"12.3"	"9.09"	"378.09"	""	"1"	""	"cell cycle OR cell proliferation;other biological processes"	"nucleus;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf04667"	"10776"	"ENSG00000128989"	"ARPP19"	"B2R497; hsa:10776; P56211; Q6IAM2; Q86TA6; Q9UD70"	""	"MASTL Facilitates Mitotic Progression"	"1"	"0"	"35.7"	"30.1"	"42.1"	"42.0"	"33.1"	"35.3"	"91.5"	"97.3"	"159.5"	"262.3"	"277.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92882"	"Osteoclast-stimulating factor 1 OS=Homo sapiens OX=9606 GN=OSTF1 PE=1 SV=2"	"0.000"	""	"6"	"1"	"1"	"1"	"214"	"23.8"	"5.68"	"375.83"	""	"1"	""	"signal transduction;other biological processes"	"other cell component"	"other molecular function"	"Pf00018, Pf12796"	"26578"	"ENSG00000134996"	"OSTF1"	"hsa:26578; Q5W126; Q92882; Q96IJ4"	""	"Neutrophil degranulation"	"1"	"0"	"8.2"	"9.7"	"12.8"	"19.0"	"8.5"	"9.9"	"17.1"	"16.3"	"15.1"	"53.8"	"66.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WUR7"	"UPF0235 protein C15orf40 OS=Homo sapiens OX=9606 GN=C15orf40 PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"153"	"16.3"	"9.83"	"374.98"	""	"1"	""	""	"other cell component"	""	"Pf02594"	"123207"	"ENSG00000169609"	"C15orf40"	"A6NIC9; B2R5E7; F5GX92; F8WD31; G5EA00; hsa:123207; Q8WUR7"	"15q25 copy number variation"	""	"1"	"0"	"62.3"	"58.9"	"58.1"	"68.4"	"70.6"	"60.8"	"104.3"	"106.5"	"146.6"	"199.1"	"183.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NVE5"	"Ubiquitin carboxyl-terminal hydrolase 40 OS=Homo sapiens OX=9606 GN=USP40 PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1235"	"140.0"	"5.67"	"368.14"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443"	"55230"	"ENSG00000085982"	"USP40"	"hsa:55230; Q6NX38; Q70EL0; Q9NVE5"	"2q37 copy number variation syndrome"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q69YH5"	"Cell division cycle-associated protein 2 OS=Homo sapiens OX=9606 GN=CDCA2 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"1023"	"112.6"	"8.40"	"361.18"	""	"1"	""	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus;other cell component"	""	"Pf15276"	"157313"	"ENSG00000184661"	"CDCA2"	"hsa:157313; Q3SX74; Q4G0W0; Q5RKN0; Q69YH5; Q69YI4; Q6P464; Q8N7C1"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y3A3"	"MOB-like protein phocein OS=Homo sapiens OX=9606 GN=MOB4 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"225"	"26.0"	"5.78"	"355.07"	""	"1"	""	""	"other membranes;cytosol;ER/Golgi;other cell component"	"other molecular function"	"Pf03637"	"25843"	"ENSG00000115540"	"MOB4"	"B4DML0; hsa:25843; Q53SE0; Q7Z4Y6; Q9H2P3; Q9H5J1; Q9Y3A3; Q9Y4T8"	""	""	"0"	"0"	"54.5"	"48.1"	"48.9"	"55.4"	"41.0"	"42.2"	"65.9"	"61.0"	"68.2"	"222.4"	"238.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DT6"	"Cysteine protease ATG4C OS=Homo sapiens OX=9606 GN=ATG4C PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"458"	"52.5"	"5.97"	"352.70"	""	"1"	""	"protein metabolism;other metabolic processes;transport"	"other cell component"	"other molecular function"	"Pf03416, Pf20166"	"84938"	"ENSG00000125703"	"ATG4C"	"A6NLR8; D3DQ58; hsa:84938; Q96DT6; Q96K04"	"Clock-controlled autophagy in bone metabolism"	"Macroautophagy"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8N983"	"39S ribosomal protein L43, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL43 PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"215"	"23.4"	"8.65"	"350.23"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf05047"	"84545"	"ENSG00000055950"	"MRPL43"	"B1AL06; B1AL07; B1AL09; B1AL10; C9J5Q3; D3DR71; hsa:84545; Q5JW06; Q7Z719; Q7Z7H6; Q86XN1; Q8N983; Q9BYC7"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"19.3"	"19.0"	"25.9"	"38.0"	"19.5"	"21.0"	"37.0"	"47.0"	"65.8"	"119.2"	"171.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9ULX3"	"RNA-binding protein NOB1 OS=Homo sapiens OX=9606 GN=NOB1 PE=1 SV=1"	"0.000"	""	"4"	"1"	"1"	"1"	"412"	"46.6"	"7.18"	"341.16"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf08772, Pf15017, Pf17146"	"28987"	"ENSG00000141101"	"NOB1"	"hsa:28987; Q7L6B7; Q7M4M4; Q7Z4B5; Q9NWB0; Q9ULX3"	""	"Major pathway of rRNA processing in the nucleolus and cytosol"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NXX6"	"Non-structural maintenance of chromosomes element 4 homolog A OS=Homo sapiens OX=9606 GN=NSMCE4A PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"385"	"44.3"	"5.38"	"333.90"	""	"1"	""	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	""	"Pf08743, Pf15412"	"54780"	"ENSG00000107672"	"NSMCE4A"	"hsa:54780; Q5SQQ5; Q6P673; Q8WY66; Q9BS90; Q9NXX6"	""	"SUMOylation of DNA damage response and repair proteins"	"1"	"0"	"73.9"	"57.7"	"75.7"	"78.1"	"70.9"	"78.6"	"98.9"	"91.9"	"117.1"	"263.4"	"338.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96SZ6"	"Mitochondrial tRNA methylthiotransferase CDK5RAP1 OS=Homo sapiens OX=9606 GN=CDK5RAP1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"601"	"67.6"	"8.21"	"333.53"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;developmental processes;other biological processes"	"cytosol;mitochondrion;nucleus"	"other molecular function"	"Pf00919, Pf01938, Pf04055"	"51654"	"ENSG00000101391"	"CDK5RAP1"	"A8K7R0; hsa:51654; Q5QP46; Q5QP47; Q5QP48; Q675N4; Q675N5; Q96SZ6; Q9BVG6; Q9BWZ5; Q9H859; Q9NZZ9; Q9Y3F0"	""	""	"0"	"0"	"6.0"	"5.1"	"8.5"	"9.1"	"6.7"	"6.7"	"13.4"	"9.0"	"14.4"	"29.3"	"31.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NHQ9"	"ATP-dependent RNA helicase DDX55 OS=Homo sapiens OX=9606 GN=DDX55 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"600"	"68.5"	"9.25"	"332.74"	""	"1"	""	""	"cytosol;nucleus"	"other molecular function"	"Pf00270, Pf00271, Pf13959"	"57696"	"ENSG00000111364"	"DDX55"	"hsa:57696; Q658L6; Q8IYH0; Q8NHQ9; Q9HCH7"	""	""	"0"	"0"	"4.7"	"8.8"	"8.7"	"6.8"	"7.3"	"5.6"	"11.6"	"8.9"	"14.2"	"38.4"	"54.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P2K5"	"Myelin expression factor 2 OS=Homo sapiens OX=9606 GN=MYEF2 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"600"	"64.1"	"8.75"	"319.89"	""	"1"	""	"developmental processes;other biological processes"	"nucleus"	"nucleic acid binding activity"	"Pf00076"	"50804"	"ENSG00000104177"	"MYEF2"	"A7MCZ9; C9J921; C9K0J4; hsa:50804; Q6NUM5; Q7L388; Q7Z4B7; Q9H922; Q9NUQ1; Q9P2K5"	"Physiological and pathological hypertrophy of the heart; MicroRNAs in cardiomyocyte hypertrophy; Transcription factors regulate miRNAs related to cardiac hypertrophy; Mitochondrial gene expression"	""	"4"	"0"	"29.6"	"20.7"	"54.3"	"46.8"	"28.9"	"36.9"	"43.9"	"39.4"	"55.1"	"91.3"	"115.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969U7"	"Proteasome assembly chaperone 2 OS=Homo sapiens OX=9606 GN=PSMG2 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"264"	"29.4"	"6.98"	"316.55"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;signal transduction;other biological processes"	"cytosol;other cell component"	"other molecular function"	"Pf09754"	"56984"	"ENSG00000128789"	"PSMG2"	"B0YJB3; hsa:56984; Q6IAH4; Q969U7; Q9NRV1; V9GYH7"	""	""	"0"	"0"	"13.0"	"7.5"	"6.6"	"16.8"	"10.3"	"9.7"	"23.6"	"36.7"	"95.9"	"261.7"	"437.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P42566"	"Epidermal growth factor receptor substrate 15 OS=Homo sapiens OX=9606 GN=EPS15 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"896"	"98.6"	"4.64"	"314.83"	""	"1"	""	"cell organization and biogenesis;transport;other biological processes"	"plasma membrane;other membranes;cytosol;other cytoplasmic organelle;other cell component"	"other molecular function"	""	"2060"	"ENSG00000085832"	"EPS15"	"B2R8J7; D3DPJ2; hsa:2060; P42566; Q5SRH4"	"VEGFA-VEGFR2 signaling; Ebola virus infection in host; EGF/EGFR signaling pathway"	"Cargo recognition for clathrin-mediated endocytosis; EGFR downregulation; Negative regulation of MET activity; InlB-mediated entry of Listeria monocytogenes into host cell"	"8"	"0"	"52.4"	"57.2"	"57.5"	"67.6"	"43.9"	"54.3"	"184.2"	"209.4"	"282.9"	"546.6"	"471.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UI08"	"Ena/VASP-like protein OS=Homo sapiens OX=9606 GN=EVL PE=1 SV=2"	"0.000"	""	"5"	"1"	"1"	"1"	"416"	"44.6"	"8.84"	"312.86"	""	"1"	""	"cell organization and biogenesis;developmental processes;signal transduction;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00568, Pf08776"	"51466"	"ENSG00000196405"	"EVL"	"A8K105; B7Z3I5; hsa:51466; O95884; Q7Z522; Q8TBV1; Q9UF25; Q9UI08; Q9UIC2"	""	"RHO GTPases Activate Formins; Generation of second messenger molecules; Signaling by ROBO receptors"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UQ84"	"Exonuclease 1 OS=Homo sapiens OX=9606 GN=EXO1 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"846"	"94.0"	"8.31"	"308.00"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"plasma membrane;other membranes;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf00752, Pf00867"	"9156"	"ENSG00000174371"	"EXO1"	"hsa:9156; O60545; O75214; O75466; Q5T396; Q96IJ1; Q9UG38; Q9UNW0; Q9UQ84"	"DNA repair pathways, full network; DNA mismatch repair; Primary ovarian insufficiency"	"Regulation of TP53 Activity through Phosphorylation; Resolution of D-loop Structures through Holliday Junction Intermediates; Processing of DNA double-strand break ends; Presynaptic phase of homologous DNA pairing and strand exchange; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha); Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)"	"19"	"0"	"6.9"	"9.7"	"7.5"	"10.6"	"10.0"	"7.4"	"11.1"	"10.6"	"9.9"	"19.2"	"23.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A1L0T0"	"2-hydroxyacyl-CoA lyase 2 OS=Homo sapiens OX=9606 GN=ILVBL PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"632"	"67.8"	"8.15"	"305.23"	""	"1"	""	"other metabolic processes"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf00205, Pf02775, Pf02776"	"10994"	"ENSG00000105135"	"ILVBL"	"A1L0T0; hsa:10994; O43341; Q96F08; Q99651; Q9BWN5; Q9UEB2"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P04818"	"Thymidylate synthase OS=Homo sapiens OX=9606 GN=TYMS PE=1 SV=3"	"0.000"	""	"6"	"1"	"1"	"1"	"313"	"35.7"	"7.01"	"304.24"	""	"1"	""	"DNA metabolism;other metabolic processes;developmental processes;other biological processes"	"other membranes;cytosol;mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00303"	"7298"	"ENSG00000176890"	"TYMS"	"hsa:7298; P04818; Q8WYK3; Q8WYK4"	"Fluoropyrimidine activity; One-carbon metabolism; Retinoblastoma gene in cancer; Trans-sulfuration, one-carbon metabolism and related pathways; Ethanol effects on histone modifications; Pyrimidine metabolism"	"Interconversion of nucleotide di- and triphosphates; G1/S-Specific Transcription"	"8"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q07889"	"Son of sevenless homolog 1 OS=Homo sapiens OX=9606 GN=SOS1 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"1333"	"152.4"	"6.84"	"295.36"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;cytosol;other cell component"	"signal transduction activity or receptor binding;enzyme regulator activity;other molecular function"	"Pf00169, Pf00617, Pf00618, Pf00621"	"6654"	"ENSG00000115904"	"SOS1"	"A8K2G3; B4DXG2; hsa:6654; Q07889"	"IL-5 signaling pathway; Integrin-mediated cell adhesion; Leptin signaling pathway; Prolactin signaling pathway; Pilocytic astrocytoma; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; Oncostatin M signaling pathway; Alpha 6 beta 4 signaling pathway; IL-3 signaling pathway; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; RAC1/PAK1/p38/MMP2 pathway; IL6 signaling pathway; Hepatitis C and hepatocellular carcinoma; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; T-cell antigen receptor (TCR) pathway during Staphylococcus aureus infection; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Endometrial cancer; PI3K-Akt signaling pathway; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Acute viral myocarditis; Thermogenesis; EGF/EGFR signaling pathway; Envelope proteins and their potential roles in EDMD physiopathology; Fragile X syndrome; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Thyroid hormones production and peripheral downstream signaling effects; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; IL-2 signaling pathway; MAPK pathway in congenital thyroid cancer; Pleural mesothelioma; Regulation of actin cytoskeleton; 4p16.3 copy number variation; 5q35 copy number variation; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent)"	"Role of LAT2/NTAL/LAB on calcium mobilization; RET signaling; Downstream signal transduction; Tie2 Signaling; Signaling by CSF1 (M-CSF) in myeloid cells; FRS-mediated FGFR1 signaling; FRS-mediated FGFR2 signaling; FRS-mediated FGFR3 signaling; FRS-mediated FGFR4 signaling; FLT3 Signaling; Activated NTRK2 signals through FRS2 and FRS3; Signaling by FLT3 ITD and TKD mutants; FCERI mediated MAPK activation; FCERI mediated Ca+2 mobilization; Potential therapeutics for SARS; Antigen activates B Cell Receptor (BCR) leading to generation of second messengers; RAC1 GTPase cycle; NRAGE signals death through JNK; G alpha (12/13) signalling events; Interleukin receptor SHC signaling; RAF/MAP kinase cascade; DAP12 signaling; Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants; Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants; Signaling by PDGFRA extracellular domain mutants; Regulation of KIT signaling; SHC1 events in ERBB2 signaling; SHC1 events in ERBB4 signaling; GRB2 events in ERBB2 signaling; Signaling by ERBB2 KD Mutants; Signaling by ERBB2 TMD/JMD mutants; GRB2 events in EGFR signaling; SHC1 events in EGFR signaling; NCAM signaling for neurite out-growth; Signaling by FGFR1 in disease; SHC-mediated cascade:FGFR1; SHC-mediated cascade:FGFR2; Signaling by FGFR2 in disease; SHC-mediated cascade:FGFR3; SHC-mediated cascade:FGFR4; Signaling by FGFR3 in disease; Activation of RAC1; Erythropoietin activates RAS; Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants; EGFR Transactivation by Gastrin; Constitutive Signaling by EGFRvIII; Signaling by ERBB2 ECD mutants; SOS-mediated signalling; Signalling to RAS; SHC-related events triggered by IGF1R; Signaling by FGFR4 in disease; MET activates RAS signaling; Activated NTRK2 signals through RAS; Activated NTRK3 signals through RAS; Constitutive Signaling by Overexpressed ERBB2; Signaling by FLT3 fusion proteins; Signal attenuation; GRB2:SOS provides linkage to MAPK signaling for Integrins ; Interleukin-15 signaling"	"115"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15386"	"Ubiquitin-protein ligase E3C OS=Homo sapiens OX=9606 GN=UBE3C PE=1 SV=3"	"0.000"	""	"1"	"1"	"1"	"1"	"1083"	"123.8"	"6.71"	"293.26"	""	"1"	""	"protein metabolism;other metabolic processes"	"other cell component"	"enzyme regulator activity;other molecular function"	"Pf00632"	"9690"	"ENSG00000009335"	"UBE3C"	"A4D235; A6NCP3; hsa:9690; Q15386; Q8TC15; Q96CR4; Q9UDU3"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	"31.2"	"18.9"	"35.4"	"52.6"	"33.7"	"35.6"	"60.5"	"53.4"	"93.6"	"175.1"	"246.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13057"	"Bifunctional coenzyme A synthase OS=Homo sapiens OX=9606 GN=COASY PE=1 SV=4"	"0.000"	""	"3"	"1"	"1"	"1"	"564"	"62.3"	"6.99"	"291.33"	""	"1"	""	"other metabolic processes"	"other membranes;mitochondrion"	"kinase activity;other molecular function"	"Pf01121, Pf01467"	"80347"	"ENSG00000068120"	"COASY"	"B2RA78; B4DLU0; hsa:80347; Q13057; Q6GS23; Q8NBM7; Q8NEW1; Q8WXD4; Q9NRM3"	"Neurodegeneration with brain iron accumulation (NBIA) subtypes pathway"	"Coenzyme A biosynthesis"	"2"	"0"	"18.5"	"23.5"	"27.3"	"21.8"	"21.4"	"23.7"	"35.9"	"37.7"	"59.6"	"121.4"	"169.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPN3"	"Microtubule-actin cross-linking factor 1, isoforms 1/2/3/5 OS=Homo sapiens OX=9606 GN=MACF1 PE=1 SV=4"	"0.000"	""	"0"	"1"	"1"	"1"	"7388"	"837.8"	"5.39"	"290.93"	""	"1"	""	"cell-cell signaling;cell organization and biogenesis;stress response;transport;signal transduction;other biological processes"	"plasma membrane;other membranes;cytoskeleton;ER/Golgi;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00307, Pf00435, Pf00681, Pf02187, Pf13499, Pf17902, Pf18373"	"23499"	"ENSG00000127603"	"MACF1"	"B1ALC5; E9PJT0; hsa:23499; O75053; Q5VW20; Q8WXY1; Q8WXY2; Q96PK2; Q9H540; Q9UKP0; Q9ULG9; Q9UPN3"	"Mesodermal commitment pathway; Mesodermal commitment pathway"	""	"2"	"0"	"27.6"	"22.4"	"33.6"	"39.1"	"19.1"	"28.8"	"49.0"	"40.0"	"60.9"	"220.7"	"321.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VX52"	"Spermatogenesis-associated protein 1 OS=Homo sapiens OX=9606 GN=SPATA1 PE=2 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"459"	"52.9"	"8.85"	"290.67"	""	"1"	""	""	"other cell component"	""	"Pf15743"	"100505741"	""	"SPATA1"	"A0A1W2PQB0; A0PJU9; hsa:100505741; Q0VDJ9; Q0VDK0; Q5VX52; Q6P386; Q9HAR4"	""	""	"0"	"0"	"119.0"	"113.7"	"150.4"	"176.5"	"108.6"	"115.6"	"198.7"	"200.8"	"251.9"	"567.9"	"781.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NYY8"	"FAST kinase domain-containing protein 2, mitochondrial OS=Homo sapiens OX=9606 GN=FASTKD2 PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"710"	"81.4"	"8.05"	"289.74"	""	"1"	""	"cell organization and biogenesis;protein metabolism;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"mitochondrion;other cell component"	"nucleic acid binding activity"	"Pf06743, Pf08368, Pf08373"	"22868"	"ENSG00000118246"	"FASTKD2"	"hsa:22868; Q9NVX6; Q9NYY8; Q9Y2H7"	""	""	"0"	"0"	"17.2"	"18.1"	"20.0"	"21.6"	"17.1"	"14.7"	"48.2"	"42.5"	"66.7"	"261.6"	"432.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P37837"	"Transaldolase OS=Homo sapiens OX=9606 GN=TALDO1 PE=1 SV=2"	"0.000"	""	"2"	"1"	"1"	"1"	"337"	"37.5"	"6.81"	"289.63"	""	"1"	""	"other metabolic processes"	"cytosol;other cell component"	"other molecular function"	"Pf00923"	"6888"	"ENSG00000177156"	"TALDO1"	"B2R8M2; hsa:6888; O00751; P37837; Q8WV32; Q8WZ45"	"Pentose phosphate metabolism; Cori cycle; Metabolic reprogramming in colon cancer"	"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; NFE2L2 regulates pentose phosphate pathway genes; Pentose phosphate pathway; Insulin effects increased synthesis of Xylulose-5-Phosphate; TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P; TALDO1 deficiency: failed conversion of  Fru(6)P, E4P to SH7P, GA3P"	"9"	"0"	"110.5"	"109.7"	"224.4"	"323.7"	"88.3"	"90.3"	"221.7"	"232.7"	"264.8"	"633.9"	"811.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96DE0"	"U8 snoRNA-decapping enzyme OS=Homo sapiens OX=9606 GN=NUDT16 PE=1 SV=2"	"0.000"	""	"8"	"1"	"1"	"1"	"195"	"21.3"	"6.89"	"284.75"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293"	"131870"	"ENSG00000198585"	"NUDT16"	"B4E3B4; E9PED4; F5GYJ1; hsa:131870; Q96DE0; Q96N82"	""	"Phosphate bond hydrolysis by NUDT proteins"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28482"	"Mitogen-activated protein kinase 1 OS=Homo sapiens OX=9606 GN=MAPK1 PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"360"	"41.4"	"6.98"	"283.85"	""	"1"	""	"cell-cell signaling;cell cycle OR cell proliferation;protein metabolism;other metabolic processes;stress response;transport;developmental processes;signal transduction;other biological processes"	"non-structural extracellular;plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cytoplasmic organelle;other cell component"	"nucleic acid binding activity;kinase activity;other molecular function"	"Pf00069"	"5594"	"ENSG00000100030"	"MAPK1"	"A8CZ64; hsa:5594; P28482"	"IL-5 signaling pathway; Osteopontin signaling; Physiological and pathological hypertrophy of the heart; Angiogenesis; MicroRNAs in cardiomyocyte hypertrophy; Type II diabetes mellitus; Heart development; Integrin-mediated cell adhesion; IL-1 signaling pathway; Thyroxine (thyroid hormone) production; RANKL/RANK signaling pathway; Thyroid stimulating hormone (TSH) signaling pathway; Leptin signaling pathway; Follicle stimulating hormone (FSH) signaling pathway; TNF-related weak inducer of apoptosis (TWEAK) signaling pathway; Prolactin signaling pathway; IL-7 signaling pathway; Alzheimer's disease and miRNA effects; IL-17 signaling pathway; Endothelin pathways; IL-9 signaling pathway; Thymic stromal lymphopoietin (TSLP) signaling pathway; Glioblastoma signaling pathways; Androgen receptor network in prostate cancer; B cell receptor signaling pathway; TNF-alpha signaling pathway; AGE/RAGE pathway; Interleukin-11 signaling pathway; Corticotropin-releasing hormone signaling pathway; Oncostatin M signaling pathway; Brain-derived neurotrophic factor (BDNF) signaling pathway; Spinal cord injury; Alpha 6 beta 4 signaling pathway; PDGF pathway; Aryl hydrocarbon receptor pathway; S1P receptor signal transduction; Ebstein-Barr virus LMP1 signaling; Common pathways underlying drug addiction; Interleukin-1 (IL-1) structural pathway; Cardiac hypertrophic response; Bladder cancer; IL-3 signaling pathway; Apoptosis-related network due to altered Notch3 in ovarian cancer; TCA cycle nutrient use and invasiveness of ovarian cancer; Kit receptor signaling pathway; Focal adhesion; Hepatocyte growth factor receptor signaling; MFAP5-mediated ovarian cancer cell motility and invasiveness; RAC1/PAK1/p38/MMP2 pathway; Wnt signaling pathway; IL6 signaling pathway; Hypothesized pathways in pathogenesis of cardiovascular disease; BDNF-TrkB signaling; Physico-chemical features and toxicity-associated pathways; MAPK signaling pathway; MAPK and NFkB signaling pathways inhibited by Yersinia YopJ; ERK pathway in Huntington's disease; Toll-like receptor signaling related to MyD88; TGF-beta signaling in thyroid cells for epithelial-mesenchymal transition; 4-hydroxytamoxifen, dexamethasone, and retinoic acids regulation of p27 expression; VEGFA-VEGFR2 signaling; Angiopoietin-like protein 8 regulatory pathway; Chemokine signaling pathway; Embryonic stem cell pluripotency pathways; Focal adhesion: PI3K-Akt-mTOR-signaling pathway; IL-4 signaling pathway; Prion disease pathway; Endometrial cancer; PI3K-Akt signaling pathway; Chromosomal and microsatellite instability in colorectal cancer ; Ebola virus infection in host; MAPK cascade; Ras signaling; Epithelial to mesenchymal transition in colorectal cancer; Non-small cell lung cancer; Breast cancer pathway; Pancreatic adenocarcinoma pathway; Acute viral myocarditis; Inhibition of exosome biogenesis and secretion by Manumycin A in CRPC cells; Neovascularisation processes; Non-genomic actions of 1,25 dihydroxyvitamin D3; EGF/EGFR signaling pathway; Bile acids synthesis and enterohepatic circulation ; Resistin as a regulator of inflammation; Relationship between inflammation, COX-2 and EGFR; Envelope proteins and their potential roles in EDMD physiopathology; Regulatory circuits of the STAT3 signaling pathway; Synaptic signaling pathways associated with autism spectrum disorder; Fragile X syndrome; FBXL10 enhancement of MAP/ERK signaling in diffuse large B-cell lymphoma; MFAP5 effect on permeability and motility of endothelial cells via cytoskeleton rearrangement; Translation inhibitors in chronically activated PDGFRA cells; Gastrin signaling pathway; Hepatitis B infection; Melanoma; Netrin-UNC5B signaling pathway; IL-18 signaling pathway; FGFR3 signaling in chondrocyte proliferation and terminal differentiation; Osteoblast differentiation and related diseases; EGFR tyrosine kinase inhibitor resistance; Insulin signaling; Regucalcin in proximal tubule epithelial kidney cells; Kisspeptin/kisspeptin receptor system in the ovary; MAP3K1 role in promoting and blocking gonadal determination; CAMKK2 pathway; Disruption of postsynaptic signaling by CNV; Host-pathogen interaction of human coronaviruses - MAPK signaling; IL-2 signaling pathway; RAS and bradykinin pathways in COVID-19; Angiotensin II receptor type 1 pathway; Kallmann syndrome; Neuroinflammation and glutamatergic signaling; Pleural mesothelioma; Orexin receptor pathway; CCL18 signaling pathway; Regulation of actin cytoskeleton; Sphingolipid metabolism in senescence; Alzheimer's disease; Th17 cell differentiation pathway; GDNF signaling; 2q11.2 copy number variation syndrome; 2q13 copy number variation syndrome; Hippocampal synaptogenesis and neurogenesis; Comprehensive IL-17A signaling; Genetic causes of porto-sinusoidal vascular disease; Female steroid hormones in cardiomyocyte energy metabolism; Cardiomyocyte signaling pathways converging on Titin; 8p23.1 copy number variation syndrome; IL-26 signaling pathways; A network map of Macrophage-stimulating protein (MSP) signaling; 4p16.3 copy number variation; Role of hypoxia, angiogenesis, and FGF pathway in OA chondrocyte hypertrophy; NPHP1 deletion syndrome; EPO receptor signaling; ErbB signaling pathway; T-cell receptor signaling pathway; DNA damage response (only ATM dependent); Estrogen signaling pathway; Vitamin A and carotenoid metabolism; Toll-like receptor signaling pathway"	"NPAS4 regulates expression of target genes; Estrogen-dependent nuclear events downstream of ESR-membrane signaling; Recycling pathway of L1; Downregulation of SMAD2/3:SMAD4 transcriptional activity; Neutrophil degranulation; Regulation of actin dynamics for phagocytic cup formation; FCERI mediated MAPK activation; FCGR3A-mediated phagocytosis; RHO GTPases Activate WASPs and WAVEs; Regulation of HSF1-mediated heat shock response; Signaling by BRAF and RAF1 fusions; Thrombin signalling through proteinase activated receptors (PARs); SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription; Oxidative Stress Induced Senescence; Regulation of PTEN gene transcription; Signaling by NODAL; PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling; Interferon gamma signaling; Oncogene Induced Senescence; Senescence-Associated Secretory Phenotype (SASP); Growth hormone receptor signaling; Regulation of the apoptosome activity; Signal transduction by L1; NCAM signaling for neurite out-growth; RUNX2 regulates osteoblast differentiation; RSK activation; Estrogen-stimulated signaling through PRKCZ; Spry regulation of FGF signaling; Suppression of apoptosis; MAPK1 (ERK2) activation; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; Signaling by RAF1 mutants; IFNG signaling activates MAPKs; Golgi Cisternae Pericentriolar Stack Reorganization; Signaling by Activin; Activation of the AP-1 family of transcription factors; MAP2K and MAPK activation; Signaling by high-kinase activity BRAF mutants; Frs2-mediated activation; Signal attenuation; Gastrin-CREB signalling pathway via PKC and MAPK; Nuclear events stimulated by ALK signaling in cancer; ESR-mediated signaling; Negative feedback regulation of MAPK pathway; Advanced glycosylation endproduct receptor signaling; RHO GTPases Activate NADPH Oxidases; ERKs are inactivated; Signaling by MAP2K mutants; phospho-PLA2 pathway; Signaling by MAPK mutants"	"200"	"0"	"70.6"	"76.7"	"105.4"	"132.5"	"75.9"	"90.6"	"197.2"	"215.0"	"284.0"	"505.9"	"670.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y6A5"	"Transforming acidic coiled-coil-containing protein 3 OS=Homo sapiens OX=9606 GN=TACC3 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"838"	"90.3"	"5.05"	"281.66"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	""	"Pf05010"	"10460"	"ENSG00000013810"	"TACC3"	"hsa:10460; Q2NKK4; Q3KQS5; Q9UMQ1; Q9Y6A5"	"4p16.3 copy number variation"	"Negative regulation of NOTCH4 signaling; NOTCH3 Activation and Transmission of Signal to the Nucleus"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8NE86"	"Calcium uniporter protein, mitochondrial OS=Homo sapiens OX=9606 GN=MCU PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"351"	"39.8"	"8.65"	"279.81"	""	"1"	""	"cell organization and biogenesis;transport;signal transduction;other biological processes"	"other membranes;mitochondrion"	"transporter activity;other molecular function"	"Pf04678"	"90550"	"ENSG00000156026"	"MCU"	"B2RDF3; B3KXV7; hsa:90550; Q8NE86; Q96FL3"	"Alzheimer's disease and miRNA effects; Pleural mesothelioma; Alzheimer's disease"	"Processing of SMDT1"	"5"	"0"	"30.3"	"18.6"	"29.8"	"42.4"	"23.3"	"31.6"	"36.4"	"36.2"	"53.8"	"70.8"	"108.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86W56"	"Poly(ADP-ribose) glycohydrolase OS=Homo sapiens OX=9606 GN=PARG PE=1 SV=1"	"0.000"	""	"1"	"1"	"1"	"1"	"976"	"111.0"	"6.43"	"278.96"	""	"1"	""	"DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;mitochondrion;nucleus;other cell component"	"other molecular function"	"Pf05028"	"670; 8505"	"ENSG00000227345"	"PARG"	"A5YBK3; B2RC24; B4DIU5; B4DYR4; hsa:8505; I6RUV3; Q6E4P6; Q6E4P7; Q7Z742; Q86W56; Q9Y4W7"	"10q11.21q11.23 copy number variation syndrome"	"POLB-Dependent Long Patch Base Excision Repair"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P28289"	"Tropomodulin-1 OS=Homo sapiens OX=9606 GN=TMOD1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"359"	"40.5"	"5.10"	"277.81"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"other membranes;cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf03250"	"7111"	"ENSG00000136842"	"TMOD1"	"B2RB77; hsa:7111; P28289; Q5T7W3; Q9BUF1"	"Striated muscle contraction pathway; VEGFA-VEGFR2 signaling"	"Striated Muscle Contraction"	"3"	"0"	"47.1"	"29.9"	"50.2"	"58.8"	"35.0"	"44.6"	"58.6"	"50.7"	"95.3"	"160.1"	"233.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P10586"	"Receptor-type tyrosine-protein phosphatase F OS=Homo sapiens OX=9606 GN=PTPRF PE=1 SV=2"	"0.000"	""	"0"	"1"	"1"	"1"	"1907"	"212.7"	"6.30"	"276.97"	""	"1"	""	"cell adhesion;cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;other cell component"	"other molecular function"	"Pf00041, Pf00102, Pf07679"	"5792"	"ENSG00000142949"	"PTPRF"	"D3DPX6; D3DPX7; hsa:5792; P10586; Q5T021; Q5T022; Q5W9G2; Q86WS0"	"Brain-derived neurotrophic factor (BDNF) signaling pathway; Insulin signaling"	"Insulin receptor recycling; Synaptic adhesion-like molecules; Receptor-type tyrosine-protein phosphatases"	"5"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6P1M0"	"Long-chain fatty acid transport protein 4 OS=Homo sapiens OX=9606 GN=SLC27A4 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"643"	"72.0"	"8.47"	"276.57"	""	"1"	""	"other metabolic processes;transport;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00501, Pf13193"	"10999"	"ENSG00000167114"	"SLC27A4"	"A8K2F7; hsa:10999; O95186; Q6P1M0; Q96G53"	"PPAR signaling pathway; Fatty acid transporters; Cholesterol metabolism; Fatty Acids and Lipoproteins Transport in Hepatocytes; Enterocyte cholesterol metabolism"	"Transport of fatty acids; Defective SLC27A4 causes ichthyosis prematurity syndrome (IPS)"	"7"	"0"	"5.2"	"6.1"	"6.9"	"7.2"	"5.2"	"2.1"	"7.4"	"9.5"	"12.8"	"28.4"	"39.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q6ZRY4"	"RNA-binding protein with multiple splicing 2 OS=Homo sapiens OX=9606 GN=RBPMS2 PE=1 SV=1"	"0.000"	""	"5"	"1"	"1"	"1"	"209"	"22.5"	"8.60"	"274.66"	""	"1"	""	"developmental processes;other biological processes"	"other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076"	"348093"	"ENSG00000166831"	"RBPMS2"	"A2RRG0; hsa:348093; Q6ZRY4"	""	""	"0"	"0"	"73.8"	"77.4"	"86.9"	"144.2"	"82.8"	"79.6"	"119.9"	"132.9"	"171.5"	"405.7"	"506.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q08426"	"Peroxisomal bifunctional enzyme OS=Homo sapiens OX=9606 GN=EHHADH PE=1 SV=3"	"0.000"	""	"2"	"1"	"1"	"1"	"723"	"79.4"	"9.14"	"273.14"	""	"1"	""	"other metabolic processes"	"cytosol;other cytoplasmic organelle"	"other molecular function"	"Pf00378, Pf00725, Pf02737"	"1962"	"ENSG00000113790"	"EHHADH"	"A8K6Y3; B4DWG3; D3DNU0; hsa:1962; Q08426; Q58EZ5"	"Constitutive androstane receptor pathway; PPAR-alpha pathway; Nuclear receptors meta-pathway; Mitochondrial long chain fatty acid beta-oxidation; Valproic acid pathway; Amino acid metabolism; PPAR signaling pathway; Eicosanoid metabolism via cyclooxygenases (COX); Eicosanoid metabolism via lipooxygenases (LOX); Mitochondrial fatty acid oxidation disorders"	"Peroxisomal protein import; Beta-oxidation of very long chain fatty acids"	"12"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15036"	"Sorting nexin-17 OS=Homo sapiens OX=9606 GN=SNX17 PE=1 SV=1"	"0.000"	""	"3"	"1"	"1"	"1"	"470"	"52.9"	"7.46"	"273.12"	""	"1"	""	"other metabolic processes;transport;developmental processes;signal transduction;other biological processes"	"other membranes;cytosol;ER/Golgi;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00787, Pf18116"	"9784"	"ENSG00000115234"	"SNX17"	"B4DQM7; hsa:9784; Q15036; Q53HN7; Q6IAS3"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q7Z7E8"	"Ubiquitin-conjugating enzyme E2 Q1 OS=Homo sapiens OX=9606 GN=UBE2Q1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"422"	"46.1"	"5.10"	"272.52"	""	"1"	""	"cell-cell signaling;protein metabolism;other metabolic processes;transport;developmental processes;other biological processes"	"cytosol;nucleus;other cell component"	"other molecular function"	"Pf00179"	"55585"	"ENSG00000160714"	"UBE2Q1"	"B4DF92; hsa:55585; Q29SN7; Q3B841; Q5I0X2; Q6IS04; Q6P7P2; Q7Z7E8; Q96MV4; Q9BVX5; Q9UGL6"	""	"Antigen processing: Ubiquitination & Proteasome degradation"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UBZ4"	"DNA-(apurinic or apyrimidinic site) lyase 2 OS=Homo sapiens OX=9606 GN=APEX2 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"518"	"57.4"	"8.29"	"271.68"	""	"1"	""	"cell cycle OR cell proliferation;DNA metabolism;other metabolic processes;stress response"	"mitochondrion;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf03372, Pf06839"	"27301"	"ENSG00000169188"	"APEX2"	"hsa:27301; Q9UBZ4; Q9Y5X7"	"Base excision repair; DNA repair pathways, full network"	""	"2"	"0"	"26.1"	"27.6"	"24.4"	"24.6"	"31.0"	"12.0"	"33.0"	"40.6"	"41.7"	"76.7"	"66.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P30086"	"Phosphatidylethanolamine-binding protein 1 OS=Homo sapiens OX=9606 GN=PEBP1 PE=1 SV=3"	"0.000"	""	"4"	"1"	"1"	"1"	"187"	"21.0"	"7.53"	"268.83"	""	"1"	""	"other biological processes"	"cytosol"	"enzyme regulator activity;other molecular function"	"Pf01161"	"5037"	"ENSG00000089220"	"PEBP1"	"B2R4S1; hsa:5037; P30086"	"Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"Signaling by BRAF and RAF1 fusions; Signaling by moderate kinase activity BRAF mutants; Paradoxical activation of RAF signaling by kinase inactive BRAF; Signaling downstream of RAS mutants; MAP2K and MAPK activation; Negative regulation of MAPK pathway; Signaling by high-kinase activity BRAF mutants"	"9"	"0"	"100.5"	"82.0"	"126.3"	"213.9"	"85.0"	"79.8"	"143.1"	"151.1"	"153.7"	"309.0"	"478.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94972"	"E3 ubiquitin-protein ligase TRIM37 OS=Homo sapiens OX=9606 GN=TRIM37 PE=1 SV=2"	"0.000"	""	"1"	"1"	"1"	"1"	"964"	"107.8"	"5.15"	"268.33"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;transport;other biological processes"	"other membranes;cytosol;other cytoplasmic organelle;other cell component"	"signal transduction activity or receptor binding;other molecular function"	"Pf00643, Pf00917"	"4591"	"ENSG00000108395"	"TRIM37"	"A8K0V9; A8K8U4; A8MZ79; B4DGZ3; F8WEE6; hsa:4591; O94972; Q7Z3E6; Q8IYF7; Q8WYF7"	"Primary ovarian insufficiency"	"Antigen processing: Ubiquitination & Proteasome degradation"	"2"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NX07"	"tRNA selenocysteine 1-associated protein 1 OS=Homo sapiens OX=9606 GN=TRNAU1AP PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"287"	"32.5"	"4.74"	"267.22"	""	"1"	""	"protein metabolism;other metabolic processes"	"nucleus;other cell component"	"nucleic acid binding activity"	"Pf00076, Pf17654"	"54952"	"ENSG00000180098"	"TRNAU1AP"	"hsa:54952; Q86SU7; Q9NX07"	""	""	"0"	"0"	"40.9"	"37.2"	"46.5"	"48.8"	"31.8"	"32.4"	"48.7"	"56.3"	"51.5"	"82.6"	"117.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P39656"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit OS=Homo sapiens OX=9606 GN=DDOST PE=1 SV=4"	"0.000"	""	"2"	"1"	"1"	"1"	"456"	"50.8"	"6.55"	"264.90"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"enzyme regulator activity"	"Pf03345"	"1650"	"ENSG00000244038"	"DDOST"	"B2RDQ4; B4DJE3; B4DLI2; hsa:1650; O43244; P39656; Q5VWA5; Q8NI93; Q9BUI2"	"AGE/RAGE pathway; N-glycan biosynthesis"	"Neutrophil degranulation; SRP-dependent cotranslational protein targeting to membrane; Advanced glycosylation endproduct receptor signaling; Asparagine N-linked glycosylation; Maturation of spike protein"	"7"	"0"	"42.6"	"53.6"	"51.0"	"51.1"	"38.9"	"41.3"	"68.5"	"75.0"	"97.9"	"319.2"	"469.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WV74"	"Nucleoside diphosphate-linked moiety X motif 8 OS=Homo sapiens OX=9606 GN=NUDT8 PE=1 SV=2"	"0.000"	""	"4"	"1"	"1"	"1"	"236"	"25.4"	"8.41"	"264.49"	""	"1"	""	"other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf00293"	"254552"	"ENSG00000167799"	"NUDT8"	"hsa:254552; Q6ZW59; Q8WV74"	""	""	"0"	"0"	"6.0"	"5.0"	"5.6"	"8.7"	"4.6"	"2.4"	"3.3"	"5.2"	"8.9"	"30.0"	"46.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96T88"	"E3 ubiquitin-protein ligase UHRF1 OS=Homo sapiens OX=9606 GN=UHRF1 PE=1 SV=1"	"0.000"	""	"2"	"1"	"1"	"1"	"793"	"89.8"	"7.56"	"263.41"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00240, Pf00628, Pf02182, Pf12148"	"29128"	"ENSG00000276043"	"UHRF1"	"A0JBR2; A8K024; B2RBA9; hsa:29128; Q2HIX7; Q8J022; Q96T88; Q9H6S6; Q9P115; Q9P1U7"	"Pathways affected in adenoid cystic carcinoma; Pleural mesothelioma"	"DNA methylation"	"3"	"0"	"9.8"	"8.8"	"13.2"	"12.8"	"12.9"	"7.8"	"16.7"	"13.0"	"19.2"	"28.0"	"34.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NRW7"	"Vacuolar protein sorting-associated protein 45 OS=Homo sapiens OX=9606 GN=VPS45 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"570"	"65.0"	"8.24"	"259.02"	""	"1"	""	"transport"	"other membranes;ER/Golgi;other cytoplasmic organelle"	""	"Pf00995"	"11311"	"ENSG00000136631"	"VPS45"	"D3DUZ9; F5H8K1; hsa:11311; Q15715; Q53FR8; Q5T4P6; Q9NRW7; Q9Y4Z6"	""	"Intra-Golgi traffic; Factors involved in megakaryocyte development and platelet production; SARS-CoV-2 modulates autophagy"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q13627"	"Dual specificity tyrosine-phosphorylation-regulated kinase 1A OS=Homo sapiens OX=9606 GN=DYRK1A PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"763"	"85.5"	"8.75"	"258.21"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"cytoskeletal activity;kinase activity;other molecular function"	"Pf00069"	"1859"	"ENSG00000157540"	"DYRK1A"	"hsa:1859; O60769; Q13627; Q92582; Q92810; Q9UNM5"	"T cell receptor and co-stimulatory signaling; DYRK1A involvement regarding cell proliferation in brain development"	"G0 and Early G1"	"3"	"0"	"113.8"	"106.2"	"131.3"	"146.3"	"111.1"	"120.4"	"190.8"	"165.2"	"204.4"	"555.0"	"1001.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9BT43"	"DNA-directed RNA polymerase III subunit RPC7-like OS=Homo sapiens OX=9606 GN=POLR3GL PE=1 SV=1"	"0.001"	""	"3"	"1"	"1"	"1"	"218"	"25.3"	"4.54"	"256.58"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes"	"cytosol;nucleus"	""	"Pf11705"	"84265"	"ENSG00000121851"	"POLR3GL"	"B1MVG5; hsa:84265; Q9BT43"	"Pyrimidine metabolism; Cytosolic DNA-sensing pathway; TAR syndrome"	"RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; RNA Polymerase III Transcription Termination; Cytosolic sensors of pathogen-associated DNA ; RNA Polymerase III Chain Elongation"	"10"	"0"	"54.1"	"43.0"	"65.7"	"60.9"	"51.1"	"59.3"	"81.7"	"82.3"	"108.3"	"270.3"	"461.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NS91"	"E3 ubiquitin-protein ligase RAD18 OS=Homo sapiens OX=9606 GN=RAD18 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"495"	"56.2"	"7.58"	"255.95"	""	"1"	""	"protein metabolism;DNA metabolism;other metabolic processes;stress response;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf02037, Pf13923"	"56852"	"ENSG00000070950"	"RAD18"	"hsa:56852; Q58F55; Q9NRT6; Q9NS91"	"SMC1/SMC3 role in DNA damage - Cornelia de Lange Syndrome"	"Recognition of DNA damage by PCNA-containing replication complex; E3 ubiquitin ligases ubiquitinate target proteins"	"3"	"0"	"119.0"	"73.4"	"129.5"	"135.8"	"97.8"	"96.6"	"121.4"	"148.5"	"177.4"	"286.5"	"368.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UPU5"	"Ubiquitin carboxyl-terminal hydrolase 24 OS=Homo sapiens OX=9606 GN=USP24 PE=1 SV=3"	"0.001"	""	"0"	"1"	"1"	"1"	"2620"	"294.2"	"6.14"	"254.90"	""	"1"	""	"protein metabolism;other metabolic processes"	"cytosol;nucleus"	"other molecular function"	"Pf00443, Pf12030"	"23358"	"ENSG00000162402"	"USP24"	"hsa:23358; Q6ZSY2; Q8N2Y4; Q9NXD1; Q9UPU5"	""	"Ub-specific processing proteases"	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P13674"	"Prolyl 4-hydroxylase subunit alpha-1 OS=Homo sapiens OX=9606 GN=P4HA1 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"534"	"61.0"	"6.01"	"254.66"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes"	"ER/Golgi;other cell component"	"other molecular function"	"Pf08336, Pf13640"	"5033"	"ENSG00000122884"	"P4HA1"	"C9JL12; hsa:5033; P13674; Q15082; Q15083; Q5VSQ5"	"Type I collagen synthesis in the context of osteogenesis imperfecta"	"Collagen biosynthesis and modifying enzymes"	"2"	"0"	"133.9"	"123.1"	"150.7"	"229.6"	"108.7"	"100.6"	"196.6"	"212.4"	"230.8"	"411.0"	"531.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O00165"	"HCLS1-associated protein X-1 OS=Homo sapiens OX=9606 GN=HAX1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"279"	"31.6"	"4.92"	"253.93"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;ER/Golgi;nucleus;other cell component"	"other molecular function"	""	"10456"	"ENSG00000143575"	"HAX1"	"A8W4W9; A8W4X0; B4DUJ7; hsa:10456; O00165; Q5VYD5; Q5VYD7; Q96AU4; Q9BS80"	"Primary ovarian insufficiency"	""	"1"	"0"	"56.7"	"52.8"	"52.6"	"76.4"	"49.2"	"63.2"	"95.7"	"95.4"	"122.3"	"402.7"	"585.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14191"	"Werner syndrome ATP-dependent helicase OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"1432"	"162.4"	"6.34"	"253.89"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;DNA metabolism;other metabolic processes;stress response;developmental processes;other biological processes"	"cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00270, Pf00271, Pf00570, Pf01612, Pf09382, Pf14493, Pf16124"	"7486"	"ENSG00000165392"	"WRN"	"A1KYY9; hsa:7486; Q14191"	"Non-homologous end joining; DNA repair pathways, full network; Progeria-associated lipodystrophy; Primary ovarian insufficiency"	"Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Resolution of D-loop Structures through Holliday Junction Intermediates; SUMOylation of DNA damage response and repair proteins; Regulation of TP53 Activity through Phosphorylation; Presynaptic phase of homologous DNA pairing and strand exchange; Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA); Defective homologous recombination repair (HRR) due to BRCA1 loss of function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA1 binding function; Defective HDR through Homologous Recombination Repair (HRR) due to PALB2 loss of BRCA2/RAD51/RAD51C binding function; Impaired BRCA2 binding to PALB2; HDR through Single Strand Annealing (SSA); Impaired BRCA2 binding to RAD51; Removal of the Flap Intermediate from the C-strand"	"21"	"0"	"5.1"	"6.9"	"11.8"	"8.0"	"6.6"	"9.4"	"13.4"	"10.2"	"14.2"	"41.8"	"46.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P11233"	"Ras-related protein Ral-A OS=Homo sapiens OX=9606 GN=RALA PE=1 SV=1"	"0.001"	""	"3"	"1"	"1"	"1"	"206"	"23.6"	"7.11"	"252.87"	""	"1"	""	"cell cycle OR cell proliferation;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;mitochondrion;other cell component"	"signal transduction activity or receptor binding;cytoskeletal activity;other molecular function"	"Pf00071"	"5898"	"ENSG00000006451"	"RALA"	"A4D1W3; hsa:5898; P11233"	"RalA downstream regulated genes; Chromosomal and microsatellite instability in colorectal cancer ; Ras signaling; Pancreatic adenocarcinoma pathway; EGF/EGFR signaling pathway"	"Translocation of SLC2A4 (GLUT4) to the plasma membrane; Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation; p38MAPK events"	"8"	"0"	"51.1"	"52.5"	"58.6"	"68.5"	"42.9"	"65.5"	"113.3"	"111.3"	"177.1"	"352.3"	"419.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y673"	"Dolichyl-phosphate beta-glucosyltransferase OS=Homo sapiens OX=9606 GN=ALG5 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"324"	"36.9"	"9.28"	"252.84"	""	"1"	""	"protein metabolism;other metabolic processes;developmental processes"	"other membranes;ER/Golgi"	"other molecular function"	"Pf00535"	"29880"	"ENSG00000120697"	"ALG5"	"B4DR37; hsa:29880; Q5TBA6; Q9Y673"	"N-glycan biosynthesis"	"Synthesis of dolichyl-phosphate-glucose"	"2"	"0"	"14.4"	"10.8"	"15.4"	"25.4"	"7.8"	"14.4"	"32.6"	"30.4"	"48.8"	"159.9"	"188.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O75146"	"Huntingtin-interacting protein 1-related protein OS=Homo sapiens OX=9606 GN=HIP1R PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"1068"	"119.3"	"6.67"	"252.41"	""	"1"	""	"cell organization and biogenesis;transport;developmental processes;other biological processes"	"plasma membrane;other membranes;cytosol;cytoskeleton;mitochondrion;other cell component"	"cytoskeletal activity;other molecular function"	"Pf01608, Pf07651, Pf16515"	"9026"	"ENSG00000130787"	"HIP1R"	"A6NHQ6; hsa:9026; O75146; Q6NXG8; Q9UED9"	"5q35 copy number variation"	"Golgi Associated Vesicle Biogenesis; Clathrin-mediated endocytosis"	"3"	"0"	"26.8"	"20.1"	"33.0"	"35.9"	"24.9"	"33.0"	"52.3"	"67.4"	"74.7"	"195.2"	"277.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P79522"	"Proline-rich protein 3 OS=Homo sapiens OX=9606 GN=PRR3 PE=1 SV=2"	"0.001"	""	"3"	"1"	"1"	"1"	"188"	"20.6"	"9.83"	"252.34"	""	"1"	""	""	""	"other molecular function"	"Pf00642"	"80742"	"ENSG00000204576; ENSG00000206491; ENSG00000223766; ENSG00000223887; ENSG00000228186; ENSG00000229202; ENSG00000233564"	"PRR3"	"A1A4H4; hsa:80742; P79522; Q5RJB5; Q5STN6"	""	""	"0"	"0"	"187.0"	"163.1"	"229.4"	"265.4"	"191.0"	"155.5"	"255.1"	"265.7"	"280.0"	"418.7"	"557.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43709"	"Probable 18S rRNA (guanine-N(7))-methyltransferase OS=Homo sapiens OX=9606 GN=BUD23 PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"281"	"31.9"	"8.73"	"252.21"	""	"1"	""	"cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf08241, Pf12589"	"114049"	"ENSG00000071462"	"BUD23"	"A8K501; C9K060; hsa:114049; O43709; Q96P12; Q9BQ58; Q9HBP9"	"7q11.23 copy number variation syndrome"	"Major pathway of rRNA processing in the nucleolus and cytosol; rRNA modification in the nucleus and cytosol"	"3"	"0"	"165.2"	"191.5"	"195.7"	"199.8"	"145.0"	"177.5"	"256.5"	"290.2"	"341.9"	"603.8"	"505.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q4V339"	"COBW domain-containing protein 6 OS=Homo sapiens OX=9606 GN=CBWD6 PE=3 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"395"	"43.9"	"4.87"	"251.75"	""	"1"	""	""	"nucleus;other cell component"	"other molecular function"	"Pf02492, Pf07683"	"644019"	"ENSG00000215126"	"ZNG1F"	"hsa:644019; Q4V339"	""	""	"0"	"0"	"72.9"	"59.4"	"78.9"	"85.6"	"61.8"	"60.9"	"105.1"	"85.1"	"116.2"	"259.0"	"322.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96RT7"	"Gamma-tubulin complex component 6 OS=Homo sapiens OX=9606 GN=TUBGCP6 PE=1 SV=3"	"0.001"	""	"0"	"1"	"1"	"1"	"1819"	"200.4"	"6.32"	"251.23"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis"	"cytosol;cytoskeleton"	"cytoskeletal activity"	"Pf04130, Pf17681, Pf19340"	"85378"	"ENSG00000128159"	"TUBGCP6"	"hsa:85378; Q5JZ80; Q6PJ40; Q86YE9; Q96RT7; Q9BY91; Q9UGX3; Q9UGX4"	"Prader-Willi and Angelman syndrome; 15q11.2 copy number variation syndrome"	"Recruitment of NuMA to mitotic centrosomes; Recruitment of mitotic centrosome proteins and complexes"	"4"	"0"	"48.9"	"45.5"	"52.7"	"78.8"	"41.9"	"42.9"	"87.0"	"96.7"	"155.4"	"511.3"	"621.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q86UX6"	"Serine/threonine-protein kinase 32C OS=Homo sapiens OX=9606 GN=STK32C PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"486"	"55.0"	"6.61"	"250.94"	""	"1"	""	"protein metabolism;other metabolic processes;signal transduction"	""	"kinase activity;other molecular function"	"Pf00069"	"282974"	"ENSG00000165752"	"STK32C"	"hsa:282974; Q5T0Q5; Q86UE1; Q86UX6"	""	""	"0"	"0"	"2.6"	"3.8"	"2.5"	"2.5"	"6.8"	"1.7"	"19.8"	"23.1"	"44.8"	"98.9"	"127.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96JX3"	"Protein SERAC1 OS=Homo sapiens OX=9606 GN=SERAC1 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"654"	"74.1"	"7.68"	"249.98"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;transport"	"extracellular matrix;other membranes;mitochondrion;ER/Golgi;other cell component"	""	""	"84947"	"ENSG00000122335"	"SERAC1"	"hsa:84947; Q49AT1; Q5VTX3; Q6PKF3; Q96JX3"	""	""	"0"	"0"	"109.8"	"35.2"	"163.7"	"142.2"	"101.4"	"113.3"	"134.1"	"114.1"	"185.9"	"334.2"	"852.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9P0M9"	"39S ribosomal protein L27, mitochondrial OS=Homo sapiens OX=9606 GN=MRPL27 PE=1 SV=1"	"0.001"	""	"4"	"1"	"1"	"1"	"148"	"16.1"	"10.42"	"249.74"	""	"1"	""	"protein metabolism;other metabolic processes"	"other membranes;mitochondrion;translational apparatus"	"other molecular function"	"Pf01016"	"51264"	"ENSG00000108826"	"MRPL27"	"B2RE14; hsa:51264; Q9P0M9"	""	"Mitochondrial translation initiation; Mitochondrial translation elongation; Mitochondrial translation termination"	"3"	"0"	"53.7"	"58.7"	"54.3"	"80.9"	"50.4"	"45.0"	"82.5"	"95.9"	"100.0"	"306.4"	"539.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8WYA0"	"Intraflagellar transport protein 81 homolog OS=Homo sapiens OX=9606 GN=IFT81 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"676"	"79.7"	"8.82"	"249.66"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;transport;other biological processes"	"cytoskeleton;other cell component"	"cytoskeletal activity"	"Pf18383"	"28981"	"ENSG00000122970"	"IFT81"	"hsa:28981; Q2YDY1; Q8NB51; Q8WYA0; Q9BSV2; Q9UNY8"	"Ciliary landscape; Intraflagellar transport proteins binding to dynein; Genes related to primary cilium development (based on CRISPR); Ciliopathies; Alstrom syndrome; Bardet-Biedl syndrome"	"Intraflagellar transport"	"7"	"0"	"45.7"	"44.8"	"53.0"	"82.4"	"46.1"	"50.0"	"90.6"	"95.3"	"130.3"	"362.5"	"477.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q15051"	"IQ calmodulin-binding motif-containing protein 1 OS=Homo sapiens OX=9606 GN=IQCB1 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"598"	"68.9"	"9.10"	"248.88"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"other molecular function"	"Pf00612"	"9657"	"ENSG00000173226"	"IQCB1"	"hsa:9657; Q15051; Q3KS08; Q3KS09; Q5DKQ7; Q8NI79; Q9BS08"	"Ciliary landscape; Ciliopathies; Bardet-Biedl syndrome"	"Anchoring of the basal body to the plasma membrane"	"4"	"0"	"9.4"	"5.3"	"9.0"	"9.7"	"7.8"	"7.8"	"11.3"	"9.8"	"11.2"	"32.8"	"41.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q96Q07"	"BTB/POZ domain-containing protein 9 OS=Homo sapiens OX=9606 GN=BTBD9 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"612"	"69.1"	"5.77"	"248.80"	""	"1"	""	"other metabolic processes;other biological processes"	"other cell component"	""	"Pf00651, Pf00754, Pf07707"	"114781"	"ENSG00000183826"	"BTBD9"	"hsa:114781; Q494V9; Q494W1; Q96M00; Q96Q07"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9UJ41"	"Rab5 GDP/GTP exchange factor OS=Homo sapiens OX=9606 GN=RABGEF1 PE=1 SV=3"	"0.001"	""	"2"	"1"	"1"	"1"	"491"	"56.9"	"7.02"	"245.96"	""	"1"	""	"protein metabolism;other metabolic processes;transport;signal transduction;other biological processes"	"other membranes;cytosol;nucleus;other cytoplasmic organelle;other cell component"	"enzyme regulator activity;nucleic acid binding activity;other molecular function"	"Pf01754, Pf02204, Pf18151"	"27342"	"ENSG00000154710"	"RABGEF1"	"B4DZM7; hsa:27342; Q3HKR2; Q3HKR3; Q53FG0; Q9UJ41"	"16p11.2 distal deletion syndrome"	"RAB GEFs exchange GTP for GDP on RABs; TBC/RABGAPs"	"3"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"High"	"High"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O94953"	"Lysine-specific demethylase 4B OS=Homo sapiens OX=9606 GN=KDM4B PE=1 SV=4"	"0.001"	""	"1"	"1"	"1"	"1"	"1096"	"121.8"	"7.09"	"245.00"	""	"1"	""	"cell organization and biogenesis;developmental processes"	"nucleus"	"other molecular function"	"Pf02373, Pf02375, Pf13831, Pf13832, Pf18104"	"23030"	"ENSG00000127663"	"KDM4B"	"B9EGN8; D6W631; hsa:23030; O75274; O94953; Q6P3R5; Q9P1V1; Q9UF40"	""	"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Estrogen-dependent gene expression; HDMs demethylate histones"	"3"	"0"	"17.7"	"15.9"	"14.8"	"17.2"	"14.3"	"16.9"	"24.2"	"24.6"	"26.8"	"22.0"	"23.6"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q01826"	"DNA-binding protein SATB1 OS=Homo sapiens OX=9606 GN=SATB1 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"763"	"85.9"	"6.54"	"242.05"	""	"1"	""	"cell organization and biogenesis;other biological processes"	"nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00046, Pf02376, Pf16534, Pf16557"	"6304"	"ENSG00000182568"	"SATB1"	"B3KXF1; C9JTR6; hsa:6304; Q01826; Q59EQ0"	"Vitamin D receptor pathway"	"SUMOylation of chromatin organization proteins; Apoptotic cleavage of cellular proteins"	"3"	"0"	"12.6"	"8.5"	"19.6"	"25.3"	"13.5"	"11.2"	"29.9"	"35.5"	"34.2"	"97.6"	"139.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9NWV8"	"BRISC and BRCA1-A complex member 1 OS=Homo sapiens OX=9606 GN=BABAM1 PE=1 SV=1"	"0.001"	""	"6"	"1"	"1"	"1"	"329"	"36.5"	"4.64"	"241.81"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;protein metabolism;DNA metabolism;other metabolic processes;stress response;signal transduction;other biological processes"	"cytosol;nucleus;other cell component"	""	""	"29086"	"ENSG00000105393"	"BABAM1"	"A8MQT0; B4DRY9; B4DVR1; hsa:29086; Q6FIA0; Q9NWV8; Q9P018"	"5q35 copy number variation"	"Metalloprotease DUBs; Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks; Processing of DNA double-strand break ends; G2/M DNA damage checkpoint; Nonhomologous End-Joining (NHEJ)"	"6"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H936"	"Mitochondrial glutamate carrier 1 OS=Homo sapiens OX=9606 GN=SLC25A22 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"323"	"34.4"	"9.29"	"241.12"	""	"1"	""	"other metabolic processes;transport;other biological processes"	"other membranes;mitochondrion"	"transporter activity"	"Pf00153"	"79751"	"ENSG00000177542"	"SLC25A22"	"A8K366; C9J1H6; E9PJD3; E9PKB2; E9PL68; E9PN26; E9PNQ3; E9PP01; E9PR97; hsa:79751; Q8TBU8; Q9H936"	""	"Organic anion transporters"	"1"	"0"	"14.6"	"11.2"	"17.8"	"29.1"	"8.0"	"15.5"	"26.3"	"23.1"	"56.2"	"185.6"	"249.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q14721"	"Potassium voltage-gated channel subfamily B member 1 OS=Homo sapiens OX=9606 GN=KCNB1 PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"858"	"95.8"	"8.07"	"240.99"	""	"1"	""	"cell organization and biogenesis;stress response;transport;developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cell component"	"transporter activity;other molecular function"	"Pf00520, Pf02214, Pf03521"	"3745"	"ENSG00000158445"	"KCNB1"	"hsa:3745; Q14193; Q14721"	"Calcium regulation in cardiac cells"	"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion; Voltage gated Potassium channels"	"3"	"0"	"24.1"	"21.2"	"36.8"	"43.2"	"30.0"	"23.9"	"50.1"	"49.3"	"71.0"	"200.4"	"550.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8TCJ2"	"Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B OS=Homo sapiens OX=9606 GN=STT3B PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"826"	"93.6"	"8.91"	"240.50"	""	"1"	""	"protein metabolism;other metabolic processes;stress response"	"other membranes;ER/Golgi;other cell component"	"other molecular function"	"Pf02516"	"201595"	"ENSG00000163527"	"STT3B"	"hsa:201595; Q8TCJ2; Q96JZ4; Q96KY7"	"N-glycan biosynthesis"	""	"1"	"0"	"70.0"	"66.3"	"82.9"	"98.4"	"73.4"	"84.9"	"114.2"	"128.8"	"163.3"	"423.7"	"642.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5VUA4"	"Zinc finger protein 318 OS=Homo sapiens OX=9606 GN=ZNF318 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"2279"	"251.0"	"7.20"	"240.38"	""	"1"	""	"cell cycle OR cell proliferation;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	""	"24149"	"ENSG00000171467"	"ZNF318"	"hsa:24149; O94796; Q4G0E4; Q5VUA4; Q8NEM6; Q9UNU8; Q9Y2W9"	"Androgen receptor signaling pathway"	""	"1"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"n/a"	"n/a"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O95759"	"TBC1 domain family member 8 OS=Homo sapiens OX=9606 GN=TBC1D8 PE=1 SV=3"	"0.001"	""	"1"	"1"	"1"	"1"	"1140"	"130.8"	"5.52"	"240.37"	""	"1"	""	"other biological processes"	"other membranes"	"enzyme regulator activity"	"Pf00566, Pf02893"	"11138"	"ENSG00000204634"	"TBC1D8"	"A6NDL4; A8K9W1; B9A6K4; hsa:11138; O95759; Q53SQ4; Q9UQ32"	""	""	"0"	"0"	"48.3"	"41.8"	"64.3"	"63.5"	"51.8"	"79.4"	"305.2"	"337.6"	"372.7"	"311.8"	"302.8"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q5JPI3"	"Uncharacterized protein C3orf38 OS=Homo sapiens OX=9606 GN=C3orf38 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"329"	"37.5"	"6.47"	"239.88"	""	"1"	""	"other biological processes"	"nucleus"	""	"Pf15008"	"285237"	"ENSG00000179021"	"C3orf38"	"B2R8X6; hsa:285237; Q5JPI3; Q8TC85"	""	""	"0"	"0"	"436.2"	"94.9"	"760.1"	"630.6"	"424.9"	"526.3"	"501.4"	"330.9"	"407.9"	"383.8"	"637.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P55884"	"Eukaryotic translation initiation factor 3 subunit B OS=Homo sapiens OX=9606 GN=EIF3B PE=1 SV=3"	"0.001"	""	"1"	"1"	"1"	"1"	"814"	"92.4"	"5.00"	"239.30"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;other biological processes"	"cytosol;translational apparatus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00076, Pf08662"	"8662"	"ENSG00000106263"	"EIF3B"	"A4D208; hsa:8662; P55884; Q2NL77; Q9UMF9"	"Translation factors; nsp1 from SARS-CoV-2 inhibits translation initiation in the host cell"	"L13a-mediated translational silencing of Ceruloplasmin expression; Translation initiation complex formation; Formation of a pool of free 40S subunits; Formation of the ternary complex, and subsequently, the 43S complex; Ribosomal scanning and start codon recognition; GTP hydrolysis and joining of the 60S ribosomal subunit"	"8"	"0"	"72.7"	"61.5"	"84.8"	"96.3"	"68.0"	"79.5"	"113.3"	"118.5"	"135.3"	"361.9"	"807.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y625"	"Glypican-6 OS=Homo sapiens OX=9606 GN=GPC6 PE=1 SV=1"	"0.001"	""	"1"	"1"	"1"	"1"	"555"	"62.7"	"5.41"	"238.55"	""	"1"	""	"other biological processes"	"non-structural extracellular;extracellular matrix;plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	""	"Pf01153"	"10082"	"ENSG00000183098"	"GPC6"	"A8K279; hsa:10082; Q96SG5; Q96SG8; Q9H1P4; Q9Y625"	"miR-509-3p alteration of YAP1/ECM axis"	"A tetrasaccharide linker sequence is required for GAG synthesis; HS-GAG biosynthesis; HS-GAG degradation; Defective B4GALT7 causes EDS, progeroid type; Defective B3GAT3 causes JDSSDHD; Defective EXT2 causes exostoses 2; Defective EXT1 causes exostoses 1, TRPS2 and CHDS; Defective B3GALT6 causes EDSP2 and SEMDJL1; Attachment and Entry; Retinoid metabolism and transport"	"11"	"0"	"15.0"	"14.2"	"13.2"	"16.4"	"17.0"	"9.0"	"18.4"	"22.5"	"25.8"	"70.1"	"97.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q53GG5"	"PDZ and LIM domain protein 3 OS=Homo sapiens OX=9606 GN=PDLIM3 PE=1 SV=1"	"0.001"	""	"4"	"1"	"1"	"1"	"364"	"39.2"	"6.89"	"237.51"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00412, Pf00595, Pf15936"	"27295"	"ENSG00000154553"	"PDLIM3"	"B2R866; hsa:27295; O43590; O60439; O60440; Q53GG5; Q8N6Y6; Q9BVP4"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y5A9"	"YTH domain-containing family protein 2 OS=Homo sapiens OX=9606 GN=YTHDF2 PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"579"	"62.3"	"8.79"	"236.96"	""	"1"	""	"cell cycle OR cell proliferation;cell organization and biogenesis;RNA metabolism OR transcription;other metabolic processes;stress response;developmental processes;other biological processes"	"cytosol;cytoskeleton;nucleus;other cell component"	"nucleic acid binding activity"	"Pf04146"	"51441"	"ENSG00000198492"	"YTHDF2"	"A6NKG4; A8K966; B4E1G7; D3DPM8; hsa:51441; Q5VSZ9; Q8TDH0; Q9BUJ5; Q9Y5A9"	""	""	"0"	"0"	"82.7"	"95.2"	"50.7"	"75.4"	"51.0"	"72.0"	"96.7"	"105.0"	"125.4"	"280.5"	"371.1"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"A6NCE7"	"Microtubule-associated proteins 1A/1B light chain 3 beta 2 OS=Homo sapiens OX=9606 GN=MAP1LC3B2 PE=2 SV=1"	"0.001"	""	"6"	"1"	"1"	"1"	"125"	"14.6"	"8.68"	"236.78"	""	"1"	""	"cell organization and biogenesis;other metabolic processes;stress response"	"other membranes;cytosol;cytoskeleton;other cytoplasmic organelle;other cell component"	"cytoskeletal activity;other molecular function"	"Pf02991"	"643246"	"ENSG00000258102"	"MAP1LC3B2"	"A6NCE7; hsa:643246"	""	""	"0"	"0"	"63.3"	"69.7"	"85.7"	"82.9"	"70.1"	"76.1"	"111.8"	"117.3"	"158.2"	"417.6"	"512.5"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y4D8"	"Probable E3 ubiquitin-protein ligase HECTD4 OS=Homo sapiens OX=9606 GN=HECTD4 PE=1 SV=5"	"0.001"	""	"0"	"1"	"1"	"1"	"3996"	"439.1"	"6.19"	"236.21"	""	"1"	""	"protein metabolism;other metabolic processes;other biological processes"	"other membranes"	"other molecular function"	"Pf00632"	""	""	"HECTD4"	"L8B0P6; Q3MJD5; Q6P0A0; Q7L530; Q8NB70; Q8WU73; Q96NT9; Q9NZS4; Q9UFT6; Q9Y4D8"	""	""	"0"	"0"	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	""	"n/a"	"n/a"	"n/a"	"High"	"n/a"	"n/a"	"n/a"	"n/a"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P53803"	"DNA-directed RNA polymerases I, II, and III subunit RPABC4 OS=Homo sapiens OX=9606 GN=POLR2K PE=1 SV=1"	"0.001"	""	"12"	"1"	"1"	"1"	"58"	"7.0"	"9.06"	"235.86"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus"	"nucleic acid binding activity;other molecular function"	"Pf03604"	"5440"	"ENSG00000147669"	"POLR2K"	"hsa:5440; P53803; Q6IBD4"	"Pyrimidine metabolism; Eukaryotic transcription initiation; Cytosolic DNA-sensing pathway; 2q13 copy number variation syndrome"	"Formation of RNA Pol II elongation complex ; Formation of the Early Elongation Complex; Formation of HIV elongation complex in the absence of HIV Tat; Formation of the HIV-1 Early Elongation Complex; RNA Pol II CTD phosphorylation and interaction with CE during HIV infection; Formation of HIV-1 elongation complex containing HIV-1 Tat; Pausing and recovery of Tat-mediated HIV elongation; Abortive elongation of HIV-1 transcript in the absence of Tat; Tat-mediated HIV elongation arrest and recovery; HIV elongation arrest and recovery; Pausing and recovery of HIV elongation; RNA Polymerase II Pre-transcription Events; TP53 Regulates Transcription of DNA Repair Genes; RNA polymerase II transcribes snRNA genes; mRNA Capping; RNA Pol II CTD phosphorylation and interaction with CE; mRNA Splicing - Major Pathway; Cytosolic sensors of pathogen-associated DNA ; Viral Messenger RNA Synthesis; HIV Transcription Initiation; RNA Polymerase II HIV Promoter Escape; RNA Polymerase II Promoter Escape; RNA Polymerase II Transcription Pre-Initiation And Promoter Opening; RNA Polymerase II Transcription Initiation; Estrogen-dependent gene expression; FGFR2 alternative splicing; mRNA Splicing - Minor Pathway; Processing of Capped Intron-Containing Pre-mRNA; Signaling by FGFR2 IIIa TM; RNA Polymerase III Abortive And Retractive Initiation; RNA Polymerase III Transcription Initiation From Type 1 Promoter; RNA Polymerase III Transcription Initiation From Type 2 Promoter; RNA Polymerase III Transcription Initiation From Type 3 Promoter; Transcriptional regulation by small RNAs; B-WICH complex positively regulates rRNA expression; NoRC negatively regulates rRNA expression; Activation of anterior HOX genes in hindbrain development during early embryogenesis; RNA Polymerase III Transcription Termination; RNA Polymerase III Chain Elongation; RNA Polymerase I Transcription Initiation; RNA Polymerase I Promoter Escape; RNA Polymerase I Transcription Termination; MicroRNA (miRNA) biogenesis; PIWI-interacting RNA (piRNA) biogenesis; Formation of TC-NER Pre-Incision Complex; Dual incision in TC-NER; Gap-filling DNA repair synthesis and ligation in TC-NER; Inhibition of DNA recombination at telomere"	"57"	"0"	"119.8"	"46.0"	"105.7"	"106.7"	"78.0"	"78.5"	"117.6"	"111.8"	"142.8"	"252.4"	"337.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q969Z3"	"Mitochondrial amidoxime reducing component 2 OS=Homo sapiens OX=9606 GN=MTARC2 PE=1 SV=1"	"0.001"	""	"2"	"1"	"1"	"1"	"335"	"38.0"	"9.16"	"235.81"	""	"1"	""	"other metabolic processes;stress response;other biological processes"	"other membranes;mitochondrion;other cytoplasmic organelle"	"other molecular function"	"Pf03473, Pf03476"	"54996"	"ENSG00000117791"	"MTARC2"	"B2D0R5; D3DTB3; hsa:54996; Q0JSK7; Q5VT67; Q5VXC7; Q7L317; Q969Z3; Q9H066; Q9NWU0"	""	"Phase I - Functionalization of compounds"	"1"	"0"	"14.0"	"14.0"	"19.0"	"26.5"	"15.7"	"13.7"	"27.9"	"33.5"	"44.3"	"148.8"	"202.4"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q92794"	"Histone acetyltransferase KAT6A OS=Homo sapiens OX=9606 GN=KAT6A PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"2004"	"224.9"	"5.68"	"235.24"	""	"1"	""	"cell organization and biogenesis;protein metabolism;other metabolic processes;stress response;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00628, Pf01853, Pf17772"	"7994"	"ENSG00000083168"	"KAT6A"	"hsa:7994; Q76L81; Q92794"	"Pathways affected in adenoid cystic carcinoma"	"Regulation of TP53 Activity through Acetylation; HATs acetylate histones"	"3"	"0"	"9.3"	"7.1"	"9.9"	"11.6"	"6.6"	"9.9"	"19.2"	"15.6"	"19.8"	"56.6"	"83.3"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9Y2K3"	"Myosin-15 OS=Homo sapiens OX=9606 GN=MYH15 PE=1 SV=5"	"0.001"	""	"0"	"1"	"1"	"1"	"1946"	"224.5"	"5.85"	"234.39"	""	"1"	""	""	"cytosol;cytoskeleton;other cell component"	"cytoskeletal activity;other molecular function"	"Pf00063, Pf01576, Pf02736"	"22989"	"ENSG00000144821"	"MYH15"	"hsa:22989; Q9Y2K3"	""	""	"0"	"0"	"43.5"	"38.8"	"46.7"	"60.9"	"40.2"	"38.3"	"73.5"	"74.6"	"77.2"	"144.3"	"218.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P0C7P0"	"CDGSH iron-sulfur domain-containing protein 3, mitochondrial OS=Homo sapiens OX=9606 GN=CISD3 PE=1 SV=1"	"0.001"	""	"5"	"1"	"1"	"1"	"127"	"14.2"	"10.55"	"234.23"	""	"1"	""	"protein metabolism;other metabolic processes"	"mitochondrion"	"other molecular function"	"Pf09360"	"284106"	"ENSG00000274768; ENSG00000277972"	"CISD3"	"hsa:284106; P0C7P0"	"17q12 copy number variation syndrome"	""	"1"	"0"	"13.6"	"9.1"	"15.3"	"19.7"	"12.0"	"16.6"	"26.5"	"24.3"	"27.5"	"81.9"	"103.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P35613"	"Basigin OS=Homo sapiens OX=9606 GN=BSG PE=1 SV=2"	"0.001"	""	"2"	"1"	"1"	"1"	"385"	"42.2"	"5.66"	"233.61"	""	"1"	""	"developmental processes;signal transduction;other biological processes"	"plasma membrane;other membranes;ER/Golgi;other cytoplasmic organelle;other cell component"	"other molecular function"	"Pf13927"	"682"	"ENSG00000172270"	"BSG"	"A6NJW1; D3YLG5; hsa:682; P35613; Q7Z796; Q8IZL7"	"Matrix metalloproteinases; VEGFA-VEGFR2 signaling; IL-18 signaling pathway"	"Degradation of the extracellular matrix; Integrin cell surface interactions; Pyruvate metabolism; Aspirin ADME; Basigin interactions; Proton-coupled monocarboxylate transport; Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT)"	"10"	"0"	"121.1"	"146.1"	"150.2"	"185.1"	"90.0"	"130.0"	"177.4"	"189.0"	"229.5"	"587.5"	"706.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q8IU60"	"m7GpppN-mRNA hydrolase OS=Homo sapiens OX=9606 GN=DCP2 PE=1 SV=3"	"0.001"	""	"1"	"1"	"1"	"1"	"420"	"48.4"	"8.00"	"233.09"	""	"1"	""	"RNA metabolism OR transcription;other metabolic processes;other biological processes"	"cytosol;nucleus;other cell component"	"nucleic acid binding activity;other molecular function"	"Pf00293, Pf05026"	"167227"	"ENSG00000172795"	"DCP2"	"C9J778; hsa:167227; Q6P2D4; Q7Z5W5; Q8IU60; Q8NBG5"	""	"mRNA decay by 5' to 3' exoribonuclease; ATF4 activates genes in response to endoplasmic reticulum  stress; KSRP (KHSRP) binds and destabilizes mRNA; Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA; Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA"	"5"	"0"	"130.6"	"147.4"	"147.4"	"161.3"	"124.7"	"91.6"	"190.1"	"182.4"	"231.6"	"386.9"	"449.0"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"P54198"	"Protein HIRA OS=Homo sapiens OX=9606 GN=HIRA PE=1 SV=2"	"0.001"	""	"1"	"1"	"1"	"1"	"1017"	"111.8"	"8.07"	"233.03"	""	"1"	""	"cell organization and biogenesis;developmental processes;other biological processes"	"nucleus;other cell component"	"other molecular function"	"Pf00400, Pf07569"	"7290"	"ENSG00000100084"	"HIRA"	"hsa:7290; P54198; Q05BU9; Q8IXN2"	"22q11.2 copy number variation syndrome; 16p11.2 proximal deletion syndrome"	"Formation of Senescence-Associated Heterochromatin Foci (SAHF)"	"3"	"0"	"77.3"	"74.5"	"70.4"	"79.1"	"67.2"	"68.1"	"107.6"	"117.6"	"155.0"	"392.8"	"502.7"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"Q9H3P7"	"Golgi resident protein GCP60 OS=Homo sapiens OX=9606 GN=ACBD3 PE=1 SV=4"	"0.001"	""	"1"	"1"	"1"	"1"	"528"	"60.6"	"5.06"	"232.70"	""	"1"	""	"other metabolic processes"	"other membranes;mitochondrion;ER/Golgi"	"other molecular function"	"Pf00887, Pf13897"	"64746"	"ENSG00000182827"	"ACBD3"	"B2RB29; hsa:64746; Q5VTJ0; Q6P9F1; Q8IZC5; Q8N4D6; Q9H3P7; Q9H6U3"	""	"Golgi Associated Vesicle Biogenesis"	"1"	"0"	"48.1"	"81.7"	"48.4"	"89.9"	"48.2"	"43.5"	"100.1"	"115.3"	"111.1"	"207.9"	"261.9"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""
"False"	"High"	"n/a"	"IsMasterProtein"	"O43708"	"Maleylacetoacetate isomerase OS=Homo sapiens OX=9606 GN=GSTZ1 PE=1 SV=3"	"0.001"	""	"3"	"1"	"1"	"1"	"216"	"24.2"	"8.54"	"231.33"	""	"1"	""	"other metabolic processes;other biological processes"	"cytosol;mitochondrion"	"other molecular function"	"Pf13417, Pf14497"	"2954"	"ENSG00000100577"	"GSTZ1"	"A6NED0; A6NNB8; A8MWD7; B2RCK3; hsa:2954; O15308; O43708; O75430; Q6IB17; Q7Z610; Q9BV63"	"Metapathway biotransformation Phase I and II"	"Regulation of pyruvate dehydrogenase (PDH) complex; Glutathione conjugation; Tyrosine catabolism"	"4"	"0"	"75.7"	"80.7"	"67.7"	"80.0"	"52.8"	"68.0"	"164.5"	"168.2"	"309.7"	"935.7"	"1043.2"	""	""	""	""	""	""	""	""	""	""	""	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"High"	"1"	""